Queries 2001 to 3000

GO:0004252

tr|M9NE75|M9NE75_DROME
Uncharacterized protein
Search

tr|M9NE78|M9NE78_DROME
Uncharacterized protein
Search

tr|M9NE79|M9NE79_DROME
Uncharacterized protein
Search

0.76	GO:0043152	induction of bacterial agglutination
0.53	GO:0032504	multicellular organism reproduction

0.70	GO:0030246	carbohydrate binding
0.45	GO:0036094	small molecule binding

0.62

GO:0005576

extracellular region

tr|M9NE84|M9NE84_DROME
Uncharacterized protein, isoform A
Search

0.10	peritrophin-1

0.78

GO:0006030

chitin metabolic process

0.77

GO:0008061

chitin binding

0.66	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|M9NE97|M9NE97_DROME
Copper transporter 1A, isoform C
Search

0.82	High affinity copper uptake protein 1

0.81	GO:0035434	copper ion transmembrane transport
0.53	GO:0002027	regulation of heart rate
0.51	GO:0006878	cellular copper ion homeostasis
0.33	GO:0010038	response to metal ion
0.33	GO:0015677	copper ion import
0.33	GO:0007283	spermatogenesis

0.82

GO:0005375

copper ion transmembrane transporter activity

0.41	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|M9NE98|M9NE98_DROME
CG5114, isoform B
Search

AAMP

0.57	angio-associated migratory cell protein

0.71	GO:0042273	ribosomal large subunit biogenesis
0.44	GO:0031163	metallo-sulfur cluster assembly
0.41	GO:0006790	sulfur compound metabolic process
0.40	GO:0051188	cofactor biosynthetic process

0.66	GO:0051082	unfolded protein binding
0.36	GO:0051539	4 iron, 4 sulfur cluster binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046872	metal ion binding

0.74	GO:0030687	preribosome, large subunit precursor
0.48	GO:0097361	CIA complex
0.46	GO:0019013	viral nucleocapsid
0.39	GO:0005634	nucleus

tr|M9NEA1|M9NEA1_DROME
Stathmin, isoform D
Search

0.63

Stathmin

0.84	GO:0031110	regulation of microtubule polymerization or depolymerization
0.54	GO:0051124	synaptic growth at neuromuscular junction
0.53	GO:0008354	germ cell migration
0.53	GO:0007298	border follicle cell migration
0.53	GO:0008088	axo-dendritic transport
0.40	GO:0007019	microtubule depolymerization
0.38	GO:0031175	neuron projection development

0.48

GO:0015631

tubulin binding

0.52	GO:0031594	neuromuscular junction
0.50	GO:0043005	neuron projection
0.41	GO:0005875	microtubule associated complex
0.40	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|M9NEB2|M9NEB2_DROME
Myosin binding subunit, isoform O
Search

LOC108089430

0.88	Myosin binding subunit, isoform O

0.58	GO:1904059	regulation of locomotor rhythm
0.58	GO:0045314	regulation of compound eye photoreceptor development
0.58	GO:0030725	germline ring canal formation
0.56	GO:0035317	imaginal disc-derived wing hair organization
0.55	GO:0007391	dorsal closure
0.55	GO:0048675	axon extension
0.53	GO:0048477	oogenesis
0.31	GO:0050790	regulation of catalytic activity
0.31	GO:0007165	signal transduction

0.78	GO:0019901	protein kinase binding
0.31	GO:0019208	phosphatase regulator activity

0.56	GO:0045179	apical cortex
0.52	GO:0043296	apical junction complex
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|M9NEB4|M9NEB4_DROME
Uncharacterized protein
Search

tr|M9NEB5|M9NEB5_DROME
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|M9NEC4|M9NEC4_DROME
Uncharacterized protein, isoform C
Search

0.11	rho GTPase-activating protein gacU

0.34

GO:0007018

microtubule-based movement

0.34	GO:0003777	microtubule motor activity
0.34	GO:0008017	microtubule binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

tr|M9NEG0|M9NEG0_DROME
Uncharacterized protein, isoform A
Search

0.61	GO:0010593	negative regulation of lamellipodium assembly
0.61	GO:2000504	positive regulation of blood vessel remodeling
0.60	GO:2001027	negative regulation of endothelial cell chemotaxis
0.60	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway
0.59	GO:0033629	negative regulation of cell adhesion mediated by integrin
0.59	GO:0002839	positive regulation of immune response to tumor cell
0.58	GO:0051894	positive regulation of focal adhesion assembly
0.58	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.57	GO:0030193	regulation of blood coagulation
0.56	GO:0030168	platelet activation

0.58	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.57	GO:0043395	heparan sulfate proteoglycan binding
0.57	GO:0019865	immunoglobulin binding
0.56	GO:0008201	heparin binding
0.51	GO:0005102	receptor binding
0.47	GO:0008270	zinc ion binding
0.46	GO:0004867	serine-type endopeptidase inhibitor activity
0.46	GO:0020037	heme binding
0.43	GO:0005544	calcium-dependent phospholipid binding
0.40	GO:0005509	calcium ion binding

0.51	GO:0036019	endolysosome
0.51	GO:0009986	cell surface
0.49	GO:0072562	blood microparticle
0.39	GO:0005634	nucleus
0.39	GO:0019013	viral nucleocapsid
0.39	GO:0061474	phagolysosome membrane
0.38	GO:0031093	platelet alpha granule lumen
0.37	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0070062	extracellular exosome
0.36	GO:0000785	chromatin

0.35

GO:0004674

tr|M9NEH1|M9NEH1_DROME
Uncharacterized protein
Search

0.69	GO:0043401	steroid hormone mediated signaling pathway
0.55	GO:0006351	transcription, DNA-templated
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:2001141	regulation of RNA biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.50	GO:0006030	chitin metabolic process
0.50	GO:0030522	intracellular receptor signaling pathway

0.70	GO:0003707	steroid hormone receptor activity
0.61	GO:0043565	sequence-specific DNA binding
0.60	GO:0008270	zinc ion binding
0.58	GO:0003700	DNA binding transcription factor activity
0.51	GO:0005496	steroid binding
0.50	GO:0008061	chitin binding

0.58	GO:0005634	nucleus
0.46	GO:0005576	extracellular region

tr|M9NEH9|M9NEH9_DROME
Mushroom-body expressed, isoform K
Search

0.70	Mushroom-body expressed, isoform K

0.52	GO:0040040	thermosensory behavior
0.50	GO:0000381	regulation of alternative mRNA splicing, via spliceosome

0.59	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.38

GO:0005634

nucleus

0.32

GO:0016787

tr|M9NEI3|M9NEI3_DROME
Cyclic nucleotide-gated ion channel-like, isoform E
Search

CNGL

0.97	Cyclic nucleotide-gated ion channel-like, isoform E

0.60	GO:0034220	ion transmembrane transport
0.50	GO:0019935	cyclic-nucleotide-mediated signaling
0.42	GO:0006812	cation transport
0.40	GO:0042391	regulation of membrane potential
0.32	GO:0006468	protein phosphorylation
0.32	GO:0034765	regulation of ion transmembrane transport

0.69	GO:0005216	ion channel activity
0.47	GO:0022834	ligand-gated channel activity
0.42	GO:0008324	cation transmembrane transporter activity
0.42	GO:0015318	inorganic molecular entity transmembrane transporter activity
0.40	GO:0022832	voltage-gated channel activity
0.33	GO:0004692	cGMP-dependent protein kinase activity

0.54	GO:0017071	intracellular cyclic nucleotide activated cation channel complex
0.38	GO:0005887	integral component of plasma membrane
0.36	GO:0005622	intracellular

0.33

EC:2.7.11.12

GO:0004692

tr|M9NEJ1|M9NEJ1_DROME
Uncharacterized protein
Search

tr|M9NEL0|M9NEL0_DROME
Uncharacterized protein
Search

tr|M9NEQ6|M9NEQ6_DROME
Uncharacterized protein
Search

tr|M9NET3|M9NET3_DROME
Uncharacterized protein
Search

tr|M9NET9|M9NET9_DROME
Uncharacterized protein
Search

tr|M9NEV5|M9NEV5_DROME
Uncharacterized protein, isoform A
Search

tr|M9NEV9|M9NEV9_DROME
Uncharacterized protein
Search

0.19	protein EMRE homolog, mitochondrial

0.86	GO:0036444	mitochondrial calcium uptake
0.85	GO:0051560	mitochondrial calcium ion homeostasis

0.86

GO:1990246

uniplex complex

tr|M9NEW0|M9NEW0_DROME
LD39232p2
Search

0.72	NADH dehydrogenase (Ubiquinone) 1 alpha subcomplex assembly factor 2

0.61	GO:0022900	electron transport chain
0.35	GO:0045333	cellular respiration

0.69	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.62	GO:0009055	electron transfer activity

0.30

GO:0016020

membrane

0.69

GO:0008137

tr|M9NEW7|M9NEW7_DROME
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|M9NEX2|M9NEX2_DROME
Uncharacterized protein
Search

tr|M9NEY2|M9NEY2_DROME
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

sp|M9NEY8|DMAD_DROME
DNA N6-methyl adenine demethylase
Search

0.86	LOW QUALITY PROTEIN: DNA N6-methyl adenine demethylase

0.42	GO:0055114	oxidation-reduction process
0.38	GO:0032259	methylation
0.35	GO:0098508	endothelial to hematopoietic transition
0.35	GO:0060319	primitive erythrocyte differentiation
0.35	GO:0070988	demethylation
0.32	GO:1901537	positive regulation of DNA demethylation
0.32	GO:0035510	DNA dealkylation
0.32	GO:0007281	germ cell development
0.32	GO:0045944	positive regulation of transcription by RNA polymerase II
0.32	GO:0044728	DNA methylation or demethylation

0.59	GO:0008270	zinc ion binding
0.52	GO:0003677	DNA binding
0.51	GO:0051213	dioxygenase activity
0.38	GO:0008168	methyltransferase activity
0.32	GO:0035516	oxidative DNA demethylase activity

0.31

GO:0005634

nucleus

0.38

GO:0008168

tr|M9NEZ1|M9NEZ1_DROME
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|M9NEZ8|M9NEZ8_DROME
Uncharacterized protein
Search

0.50	GO:0032392	DNA geometric change
0.36	GO:0055114	oxidation-reduction process

0.51	GO:0004003	ATP-dependent DNA helicase activity
0.42	GO:0030554	adenyl nucleotide binding
0.42	GO:0003677	DNA binding
0.42	GO:0032555	purine ribonucleotide binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0051213	dioxygenase activity

0.30

GO:0044425

membrane part

tr|M9NF14|M9NF14_DROME
IGF-II mRNA-binding protein, isoform L
Search

0.82	Insulin growth factor 2 mRNA-binding protein 3

0.54	GO:0048680	positive regulation of axon regeneration
0.53	GO:0051124	synaptic growth at neuromuscular junction
0.53	GO:0016322	neuron remodeling
0.49	GO:0007283	spermatogenesis
0.49	GO:0042594	response to starvation
0.42	GO:0000398	mRNA splicing, via spliceosome
0.42	GO:0005975	carbohydrate metabolic process
0.33	GO:0055085	transmembrane transport

0.59

GO:0003723

RNA binding

0.50	GO:0043025	neuronal cell body
0.50	GO:0030424	axon
0.45	GO:0071011	precatalytic spliceosome
0.44	GO:0071013	catalytic step 2 spliceosome
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|M9NF24|M9NF24_DROME
Uncharacterized protein
Search

0.84	Proteoglycan-4-like protein (Fragment)

0.48	GO:0006508	proteolysis
0.42	GO:0007160	cell-matrix adhesion
0.41	GO:0006030	chitin metabolic process
0.40	GO:0010951	negative regulation of endopeptidase activity
0.40	GO:0006955	immune response
0.39	GO:0016192	vesicle-mediated transport
0.39	GO:0098657	import into cell
0.39	GO:0034608	vulval location
0.39	GO:0034606	response to hermaphrodite contact
0.38	GO:0007016	cytoskeletal anchoring at plasma membrane

0.51	GO:0004252	serine-type endopeptidase activity
0.41	GO:0005044	scavenger receptor activity
0.41	GO:0004867	serine-type endopeptidase inhibitor activity
0.41	GO:0001871	pattern binding
0.41	GO:0008061	chitin binding
0.40	GO:0004181	metallocarboxypeptidase activity
0.39	GO:0005509	calcium ion binding
0.39	GO:0030246	carbohydrate binding
0.37	GO:0008270	zinc ion binding
0.37	GO:0005515	protein binding

0.44	GO:0005576	extracellular region
0.38	GO:0016010	dystrophin-associated glycoprotein complex
0.37	GO:0005618	cell wall
0.37	GO:0097730	non-motile cilium
0.37	GO:0043025	neuronal cell body
0.34	GO:0005581	collagen trimer
0.34	GO:0031526	brush border membrane
0.34	GO:0005902	microvillus
0.34	GO:0016324	apical plasma membrane
0.32	GO:0005622	intracellular

0.51

GO:0004252

tr|M9NF32|M9NF32_DROME
CG3793, isoform B
Search

0.62	Leucine carboxyl methyltransferase

0.63	GO:0032259	methylation
0.48	GO:0018410	C-terminal protein amino acid modification
0.46	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint
0.45	GO:0008213	protein alkylation
0.45	GO:0010906	regulation of glucose metabolic process
0.45	GO:0031333	negative regulation of protein complex assembly
0.43	GO:0042981	regulation of apoptotic process
0.34	GO:0000086	G2/M transition of mitotic cell cycle

0.63	GO:0008168	methyltransferase activity
0.40	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0005515	protein binding

0.44	GO:0005829	cytosol
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.63

GO:0008168

tr|M9NF55|M9NF55_DROME
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|M9NF77|M9NF77_DROME
Uncharacterized protein, isoform A
Search

tr|M9NF92|M9NF92_DROME
Uncharacterized protein
Search

tr|M9NFC6|M9NFC6_DROME
Uncharacterized protein, isoform B
Search

tr|M9NFE3|M9NFE3_DROME
Uncharacterized protein
Search

tr|M9NFF9|M9NFF9_DROME
Ada2a-containing complex component 3, isoform D
Search

0.97	ankyrin repeat domain-containing protein 11 isoform X1

0.69	GO:0016573	histone acetylation
0.69	GO:0006338	chromatin remodeling
0.58	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0050968	detection of chemical stimulus involved in sensory perception of pain
0.33	GO:0007635	chemosensory behavior
0.33	GO:0034220	ion transmembrane transport
0.33	GO:0016310	phosphorylation
0.32	GO:0007165	signal transduction

0.71	GO:0004402	histone acetyltransferase activity
0.58	GO:0044212	transcription regulatory region DNA binding
0.52	GO:0046982	protein heterodimerization activity
0.52	GO:0042803	protein homodimerization activity
0.44	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005216	ion channel activity
0.33	GO:0016301	kinase activity
0.33	GO:0022834	ligand-gated channel activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0140096	catalytic activity, acting on a protein

0.75	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.30	GO:0016020	membrane

0.71

GO:0004402

tr|M9NFG6|M9NFG6_DROME
Uncharacterized protein
Search

0.12	cytochrome b-c1 complex subunit 10

0.61

GO:0022900

electron transport chain

0.74

GO:0008121

ubiquinol-cytochrome-c reductase activity

0.41	GO:0031966	mitochondrial membrane
0.41	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.74

EC:1.10.2.2

GO:0008121

tr|M9NFH8|M9NFH8_DROME
CG9674, isoform F
Search

0.42	Glutamate synthase

0.77	GO:0006537	glutamate biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.40	GO:0019676	ammonia assimilation cycle

0.81	GO:0016040	glutamate synthase (NADH) activity
0.66	GO:0010181	FMN binding
0.63	GO:0051540	metal cluster binding
0.62	GO:0050660	flavin adenine dinucleotide binding
0.59	GO:0005506	iron ion binding
0.33	GO:0008483	transaminase activity

0.33

GO:0005737

cytoplasm

0.81	EC:1.4.1.14	GO:0016040
0.81	KEGG:R00093	GO:0016040

tr|M9NFI9|M9NFI9_DROME
Spinophilin, isoform J
Search

0.88

GO:1905519

negative regulation of presynaptic active zone assembly

0.85

GO:0042043

neurexin family protein binding

0.71	GO:0045179	apical cortex
0.69	GO:0070938	contractile ring

tr|M9NFK6|M9NFK6_DROME
Uncharacterized protein, isoform A
Search

0.30

GO:0044425

membrane part

tr|M9NFL7|M9NFL7_DROME
CG5665, isoform C
Search

0.33	Vitellogenin-1

0.57	GO:0006629	lipid metabolic process
0.38	GO:0045116	protein neddylation
0.37	GO:1901575	organic substance catabolic process
0.37	GO:0045995	regulation of embryonic development
0.37	GO:0032501	multicellular organismal process
0.36	GO:0009617	response to bacterium
0.35	GO:0000003	reproduction
0.35	GO:0048856	anatomical structure development
0.33	GO:0035725	sodium ion transmembrane transport
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.70	GO:0052689	carboxylic ester hydrolase activity
0.41	GO:0016298	lipase activity
0.38	GO:0019781	NEDD8 activating enzyme activity
0.36	GO:0016881	acid-amino acid ligase activity
0.34	GO:0000166	nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005272	sodium channel activity
0.33	GO:0016746	transferase activity, transferring acyl groups

0.66	GO:0005576	extracellular region
0.37	GO:0043186	P granule
0.34	GO:0000176	nuclear exosome (RNase complex)
0.30	GO:0016020	membrane

0.70	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.70	KEGG:R00630	GO:0052689

tr|M9NFM7|M9NFM7_DROME
Diabetes and obesity regulated, isoform G
Search

0.72	GO:0010506	regulation of autophagy
0.67	GO:0097306	cellular response to alcohol
0.64	GO:0008285	negative regulation of cell proliferation
0.64	GO:0035075	response to ecdysone
0.64	GO:0036315	cellular response to sterol
0.63	GO:0045893	positive regulation of transcription, DNA-templated
0.62	GO:1901655	cellular response to ketone
0.62	GO:0030518	intracellular steroid hormone receptor signaling pathway
0.54	GO:0072703	cellular response to methyl methanesulfonate
0.54	GO:0006357	regulation of transcription by RNA polymerase II

0.63	GO:0035258	steroid hormone receptor binding
0.62	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.44	GO:0016209	antioxidant activity
0.34	GO:0001106	RNA polymerase II transcription corepressor activity
0.34	GO:0019212	phosphatase inhibitor activity
0.33	GO:0003682	chromatin binding
0.33	GO:0016301	kinase activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.55	GO:0005776	autophagosome
0.45	GO:0005634	nucleus
0.44	GO:0005829	cytosol
0.35	GO:0043233	organelle lumen
0.35	GO:0031410	cytoplasmic vesicle
0.34	GO:0044446	intracellular organelle part
0.33	GO:0000428	DNA-directed RNA polymerase complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle

tr|M9NFN6|M9NFN6_DROME
Uncharacterized protein
Search

tr|M9NFN8|M9NFN8_DROME
Uncharacterized protein
Search

tr|M9NFN9|M9NFN9_DROME
Uncharacterized protein
Search

tr|M9NFP0|M9NFP0_DROME
Uncharacterized protein
Search

tr|M9NFP5|M9NFP5_DROME
Uncharacterized protein, isoform C
Search

0.44	Gamma-glutamyl transpeptidase

0.79	GO:0006751	glutathione catabolic process
0.61	GO:0006508	proteolysis
0.42	GO:0009416	response to light stimulus
0.34	GO:0032504	multicellular organism reproduction

0.80	GO:0036374	glutathione hydrolase activity
0.49	GO:0102953	hypoglycin A gamma-glutamyl transpeptidase activity
0.49	GO:0103068	leukotriene C4 gamma-glutamyl transferase activity

0.41	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.80	EC:3.4.19.13	GO:0036374
0.80	KEGG:R00494	GO:0036374

tr|M9NFP8|M9NFP8_DROME
Uncharacterized protein, isoform H
Search

0.55	SRSF protein kinase 2

0.37	GO:0006468	protein phosphorylation
0.31	GO:0006508	proteolysis

0.37	GO:0004672	protein kinase activity
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0008237	metallopeptidase activity

0.30

GO:0031224

intrinsic component of membrane

tr|M9NFQ7|M9NFQ7_DROME
RNA-binding Fox protein 1, isoform H
Search

LOC108089717

0.97	RNA-binding Fox protein 1, isoform H

0.59	GO:0030706	germarium-derived oocyte differentiation
0.59	GO:0007474	imaginal disc-derived wing vein specification
0.57	GO:0007613	memory
0.53	GO:0017148	negative regulation of translation
0.52	GO:0007399	nervous system development
0.51	GO:0045893	positive regulation of transcription, DNA-templated
0.39	GO:0043484	regulation of RNA splicing
0.37	GO:0050684	regulation of mRNA processing
0.33	GO:0008380	RNA splicing
0.32	GO:0006397	mRNA processing

0.59	GO:0003723	RNA binding
0.52	GO:0044212	transcription regulatory region DNA binding
0.51	GO:0008134	transcription factor binding

0.45	GO:0005634	nucleus
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0005737	cytoplasm
0.39	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|M9NFS2|M9NFS2_DROME
Uncharacterized protein, isoform B
Search

tr|M9NFU6|M9NFU6_DROME
Uncharacterized protein
Search

tr|M9NFW1|M9NFW1_DROME
Uncharacterized protein
Search

tr|M9NFW5|M9NFW5_DROME
Uncharacterized protein
Search

tr|M9NFY9|M9NFY9_DROME
Uncharacterized protein
Search

tr|M9NG60|M9NG60_DROME
Uncharacterized protein, isoform A
Search

tr|M9NGC6|M9NGC6_DROME
Serine-arginine protein kinase at 79D, isoform K
Search

0.97	Serine-arginine protein kinase at 79D, isoform K

0.63	GO:0006468	protein phosphorylation
0.63	GO:0048789	cytoskeletal matrix organization at active zone
0.58	GO:1990709	presynaptic active zone organization
0.55	GO:0042742	defense response to bacterium
0.55	GO:0007268	chemical synaptic transmission
0.46	GO:0000245	spliceosomal complex assembly
0.43	GO:0045070	positive regulation of viral genome replication
0.42	GO:0045071	negative regulation of viral genome replication
0.41	GO:0050684	regulation of mRNA processing
0.41	GO:0008284	positive regulation of cell proliferation

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0000287	magnesium ion binding
0.37	GO:0071889	14-3-3 protein binding
0.33	GO:0003723	RNA binding
0.33	GO:0009982	pseudouridine synthase activity

0.57	GO:0048786	presynaptic active zone
0.55	GO:0043679	axon terminus
0.40	GO:0005634	nucleus
0.38	GO:0005829	cytosol
0.38	GO:0031974	membrane-enclosed lumen
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

EC:5.4.99.12

GO:0009982

tr|M9NGE9|M9NGE9_DROME
Uncharacterized protein
Search

0.86	LOW QUALITY PROTEIN: putative nuclease HARBI1

0.30

GO:0044425

membrane part

tr|M9NGF1|M9NGF1_DROME
Uncharacterized protein
Search

tr|M9NGJ4|M9NGJ4_DROME
Uncharacterized protein, isoform D
Search

0.39	Lincomycin resistance protein lmrB

0.30

GO:0044425

membrane part

tr|M9NGP0|M9NGP0_DROME
Mnt, isoform I
Search

MNT

0.97	Mnt, isoform I

0.61	GO:0030308	negative regulation of cell growth
0.59	GO:0000122	negative regulation of transcription by RNA polymerase II
0.56	GO:0051726	regulation of cell cycle
0.39	GO:2001234	negative regulation of apoptotic signaling pathway
0.39	GO:0007569	cell aging
0.32	GO:0032259	methylation
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:0016310	phosphorylation

0.68	GO:0046983	protein dimerization activity
0.51	GO:0043565	sequence-specific DNA binding
0.47	GO:0003700	DNA binding transcription factor activity
0.38	GO:0001012	RNA polymerase II regulatory region DNA binding
0.38	GO:0003682	chromatin binding
0.37	GO:0003690	double-stranded DNA binding
0.32	GO:0008168	methyltransferase activity
0.32	GO:0016301	kinase activity

0.51	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.32

GO:0008168

tr|M9NGR4|M9NGR4_DROME
Uncharacterized protein
Search

tr|M9NGY4|M9NGY4_DROME
ZAP3, isoform E
Search

LOC108097552

0.79	collagen alpha-1(I) chain-like isoform X2

0.33	GO:0032204	regulation of telomere maintenance
0.33	GO:0000122	negative regulation of transcription by RNA polymerase II
0.32	GO:0006351	transcription, DNA-templated
0.31	GO:0098869	cellular oxidant detoxification

0.65	GO:0008157	protein phosphatase 1 binding
0.33	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.32	GO:0003723	RNA binding
0.31	GO:0004601	peroxidase activity

0.61	GO:0005634	nucleus
0.43	GO:0005581	collagen trimer
0.38	GO:0005829	cytosol
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.32	GO:0032040	small-subunit processome
0.30	GO:0016020	membrane

0.31	EC:1.11.1.7	GO:0004601
0.31	KEGG:R03532	GO:0004601

tr|M9PAZ8|M9PAZ8_DROME
CG7420, isoform B
Search

0.59	secretion-regulating guanine nucleotide exchange factor

0.52	GO:0050709	negative regulation of protein secretion
0.50	GO:0016567	protein ubiquitination
0.48	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.45	GO:0010224	response to UV-B
0.41	GO:0015940	pantothenate biosynthetic process
0.38	GO:0007165	signal transduction
0.36	GO:0055114	oxidation-reduction process

0.51	GO:0004842	ubiquitin-protein transferase activity
0.48	GO:0016874	ligase activity
0.46	GO:0004252	serine-type endopeptidase activity
0.43	GO:0009881	photoreceptor activity
0.42	GO:0042803	protein homodimerization activity
0.42	GO:0008677	2-dehydropantoate 2-reductase activity
0.38	GO:0003676	nucleic acid binding

0.52	GO:0016235	aggresome
0.49	GO:0044428	nuclear part
0.46	GO:0031461	cullin-RING ubiquitin ligase complex
0.45	GO:0005829	cytosol
0.45	GO:0031974	membrane-enclosed lumen

0.48	EC:6	GO:0016874
0.51	KEGG:R03876	GO:0004842

tr|M9PB01|M9PB01_DROME
CG7337, isoform G
Search

0.64	GO:0007346	regulation of mitotic cell cycle
0.50	GO:0007052	mitotic spindle organization
0.49	GO:0016310	phosphorylation
0.43	GO:0008380	RNA splicing

0.50	GO:0016301	kinase activity
0.38	GO:0003723	RNA binding

0.74	GO:0031021	interphase microtubule organizing center
0.67	GO:0072686	mitotic spindle
0.49	GO:0000922	spindle pole
0.46	GO:0071011	precatalytic spliceosome
0.45	GO:0005682	U5 snRNP
0.45	GO:0071013	catalytic step 2 spliceosome

tr|M9PB06|M9PB06_DROME
Uncharacterized protein, isoform D
Search

CC28B

0.72	Coiled-coil domain-containing protein 28B

0.71	GO:0060271	cilium assembly
0.50	GO:0016192	vesicle-mediated transport
0.40	GO:0015031	protein transport

0.39

GO:0004386

helicase activity

0.70	GO:0005813	centrosome
0.30	GO:0031224	intrinsic component of membrane

tr|M9PB21|M9PB21_DROME
Fatty acid synthase 2, isoform B
Search

0.52	Fatty acid synthase S-acetyltransferase

0.61	GO:0071329	cellular response to sucrose stimulus
0.55	GO:1902321	methyl-branched fatty acid biosynthetic process
0.54	GO:0006723	cuticle hydrocarbon biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.48	GO:0019432	triglyceride biosynthetic process
0.45	GO:0044042	glucan metabolic process
0.44	GO:0044264	cellular polysaccharide metabolic process
0.40	GO:0006091	generation of precursor metabolites and energy

0.85	GO:0004317	3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
0.85	GO:0004313	[acyl-carrier-protein] S-acetyltransferase activity
0.85	GO:0016295	myristoyl-[acyl-carrier-protein] hydrolase activity
0.85	GO:0016296	palmitoyl-[acyl-carrier-protein] hydrolase activity
0.85	GO:0004320	oleoyl-[acyl-carrier-protein] hydrolase activity
0.84	GO:0004319	enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity
0.77	GO:0004314	[acyl-carrier-protein] S-malonyltransferase activity
0.76	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
0.75	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity
0.74	GO:0031177	phosphopantetheine binding

0.30

GO:0016020

membrane

0.85	EC:4.2.1.61	GO:0004317
0.85	KEGG:R04462	GO:0004317

tr|M9PB26|M9PB26_DROME
Uncharacterized protein
Search

0.70

GO:0030246

carbohydrate binding

tr|M9PB30|M9PB30_DROME
Dumpy, isoform Q
Search

0.69	GO:0040005	chitin-based cuticle attachment to epithelium
0.67	GO:0007475	apposition of dorsal and ventral imaginal disc-derived wing surfaces
0.66	GO:0008362	chitin-based embryonic cuticle biosynthetic process
0.66	GO:0044719	regulation of imaginal disc-derived wing size
0.63	GO:0007424	open tracheal system development
0.52	GO:2001141	regulation of RNA biosynthetic process
0.52	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.37	GO:0010466	negative regulation of peptidase activity
0.33	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

0.70	GO:0005509	calcium ion binding
0.58	GO:0005201	extracellular matrix structural constituent
0.57	GO:0008270	zinc ion binding
0.56	GO:0003700	DNA binding transcription factor activity
0.37	GO:0030414	peptidase inhibitor activity
0.33	GO:0043021	ribonucleoprotein complex binding
0.32	GO:0003682	chromatin binding

0.56	GO:0005634	nucleus
0.54	GO:0031012	extracellular matrix
0.33	GO:0030687	preribosome, large subunit precursor
0.32	GO:0070013	intracellular organelle lumen
0.32	GO:0035003	subapical complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044446	intracellular organelle part
0.32	GO:0016324	apical plasma membrane
0.32	GO:0030139	endocytic vesicle
0.32	GO:0005770	late endosome

tr|M9PB41|M9PB41_DROME
CG4230, isoform C
Search

0.11	V-type proton ATPase subunit S1

0.30

GO:0044425

membrane part

tr|M9PB43|M9PB43_DROME
Uncharacterized protein, isoform B
Search

0.65	transmembrane protein 231

0.69	GO:0007030	Golgi organization
0.66	GO:0045930	negative regulation of mitotic cell cycle
0.41	GO:0060271	cilium assembly
0.40	GO:0032880	regulation of protein localization

0.43	GO:0060170	ciliary membrane
0.42	GO:0035869	ciliary transition zone
0.30	GO:0031224	intrinsic component of membrane

tr|M9PB71|M9PB71_DROME
CG8086, isoform I
Search

0.80	GO:0007605	sensory perception of sound
0.39	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.39	GO:0010469	regulation of receptor activity

0.40	GO:0005184	neuropeptide hormone activity
0.40	GO:0000175	3'-5'-exoribonuclease activity
0.34	GO:0003676	nucleic acid binding

0.40

EC:3.1.13

GO:0000175

tr|M9PB92|M9PB92_DROME
Cnot 4 homologue, isoform K
Search

CNOT4

0.97	CCR4-NOT transcription complex subunit 4, isoform K

0.56	GO:0046427	positive regulation of JAK-STAT cascade
0.45	GO:0016567	protein ubiquitination
0.39	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.36	GO:0006457	protein folding

0.59	GO:0003723	RNA binding
0.54	GO:0046872	metal ion binding
0.46	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0051082	unfolded protein binding
0.32	GO:0003677	DNA binding

0.39	GO:0030014	CCR4-NOT complex
0.37	GO:0016272	prefoldin complex
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.46

GO:0004842

tr|M9PBA3|M9PBA3_DROME
Uncharacterized protein, isoform A
Search

0.90	Kazal domain-containing peptide

0.63	GO:0010951	negative regulation of endopeptidase activity
0.52	GO:0032504	multicellular organism reproduction
0.47	GO:0006508	proteolysis
0.39	GO:0009405	pathogenesis

0.65	GO:0004867	serine-type endopeptidase inhibitor activity
0.48	GO:0008233	peptidase activity
0.40	GO:0090729	toxin activity
0.38	GO:0005509	calcium ion binding
0.37	GO:0008270	zinc ion binding
0.35	GO:0003676	nucleic acid binding

0.50	GO:0005615	extracellular space
0.30	GO:0044425	membrane part

0.48

GO:0008233

tr|M9PBB0|M9PBB0_DROME
Uncharacterized protein
Search

tr|M9PBB4|M9PBB4_DROME
Nimrod C1, isoform B
Search

0.54	GO:0006909	phagocytosis
0.51	GO:0042742	defense response to bacterium
0.38	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.36	GO:0006898	receptor-mediated endocytosis
0.34	GO:0007154	cell communication
0.34	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.34	GO:0048856	anatomical structure development
0.33	GO:0090287	regulation of cellular response to growth factor stimulus
0.33	GO:0023052	signaling
0.33	GO:0032501	multicellular organismal process

0.41	GO:0005509	calcium ion binding
0.39	GO:0005201	extracellular matrix structural constituent
0.37	GO:0005044	scavenger receptor activity
0.32	GO:0003676	nucleic acid binding

0.42	GO:0005886	plasma membrane
0.38	GO:0005578	proteinaceous extracellular matrix
0.32	GO:0005622	intracellular
0.30	GO:0044425	membrane part

tr|M9PBB7|M9PBB7_DROME
Uncharacterized protein
Search

tr|M9PBC6|M9PBC6_DROME
Bub3 interacting GLEBS and zinc finger domain protein, isoform F
Search

0.68	Bub3 interacting GLEBS and zinc finger domain protein, isoform F

0.59	GO:0048813	dendrite morphogenesis
0.41	GO:0090307	mitotic spindle assembly
0.40	GO:0008608	attachment of spindle microtubules to kinetochore
0.40	GO:0007094	mitotic spindle assembly checkpoint
0.35	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.34	GO:0009405	pathogenesis

0.51	GO:0003676	nucleic acid binding
0.39	GO:0008017	microtubule binding

0.42	GO:1990047	spindle matrix
0.40	GO:0000776	kinetochore
0.36	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|M9PBD0|M9PBD0_DROME
Uncharacterized protein
Search

tr|M9PBE1|M9PBE1_DROME
Uncharacterized protein, isoform C
Search

0.60	rho guanine nucleotide exchange factor 18

0.78	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.47	GO:0046579	positive regulation of Ras protein signal transduction
0.37	GO:0016310	phosphorylation
0.37	GO:0035556	intracellular signal transduction

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.38	GO:0016301	kinase activity
0.34	GO:0046872	metal ion binding

0.33

GO:0005622

intracellular

tr|M9PBE2|M9PBE2_DROME
Hakai, isoform F
Search

HAKAI

0.75	E3 ubiquitin-protein ligase Hakai

0.61	GO:0007427	epithelial cell migration, open tracheal system
0.60	GO:0008258	head involution
0.60	GO:0007494	midgut development
0.59	GO:0040003	chitin-based cuticle development
0.59	GO:0007391	dorsal closure
0.57	GO:0035282	segmentation
0.56	GO:0016567	protein ubiquitination
0.53	GO:0007015	actin filament organization
0.46	GO:0030155	regulation of cell adhesion
0.46	GO:0045807	positive regulation of endocytosis

0.56	GO:0045296	cadherin binding
0.55	GO:0016874	ligase activity
0.48	GO:0004842	ubiquitin-protein transferase activity
0.46	GO:0061659	ubiquitin-like protein ligase activity
0.42	GO:0042802	identical protein binding
0.40	GO:0008270	zinc ion binding
0.34	GO:0003743	translation initiation factor activity
0.33	GO:0008271	secondary active sulfate transmembrane transporter activity
0.32	GO:0016787	hydrolase activity

0.55	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0031410	cytoplasmic vesicle
0.43	GO:0005886	plasma membrane
0.43	GO:0016607	nuclear speck
0.33	GO:0000151	ubiquitin ligase complex
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.55	EC:6	GO:0016874
0.48	KEGG:R03876	GO:0004842

tr|M9PBF3|M9PBF3_DROME
Uncharacterized protein
Search

tr|M9PBI0|M9PBI0_DROME
Uncharacterized protein, isoform B
Search

0.61	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

tr|M9PBJ1|M9PBJ1_DROME
Zormin, isoform J
Search

0.69	GO:0007076	mitotic chromosome condensation
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:2001141	regulation of RNA biosynthetic process
0.40	GO:0010468	regulation of gene expression

0.46	GO:0003779	actin binding
0.42	GO:0003700	DNA binding transcription factor activity
0.39	GO:0003677	DNA binding

0.70	GO:0000796	condensin complex
0.51	GO:0031430	M band
0.50	GO:0030018	Z disc
0.30	GO:0031224	intrinsic component of membrane

tr|M9PBM5|M9PBM5_DROME
Uncharacterized protein, isoform B
Search

0.50	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.49	GO:0046784	viral mRNA export from host cell nucleus
0.49	GO:0051028	mRNA transport
0.48	GO:0006405	RNA export from nucleus
0.46	GO:0048666	neuron development
0.41	GO:0010467	gene expression
0.39	GO:0006468	protein phosphorylation
0.36	GO:0006265	DNA topological change
0.36	GO:0006654	phosphatidic acid biosynthetic process
0.36	GO:0018212	peptidyl-tyrosine modification

0.44	GO:0003729	mRNA binding
0.39	GO:0004672	protein kinase activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0003917	DNA topoisomerase type I activity
0.36	GO:0004630	phospholipase D activity
0.36	GO:0004601	peroxidase activity
0.36	GO:0042302	structural constituent of cuticle
0.36	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity

0.52	GO:0000445	THO complex part of transcription export complex
0.46	GO:0000784	nuclear chromosome, telomeric region
0.38	GO:0016607	nuclear speck
0.36	GO:0030123	AP-3 adaptor complex
0.36	GO:0009341	beta-galactosidase complex
0.34	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.37	EC:5.99.1.2	GO:0003917
0.36	KEGG:R03532	GO:0004601

tr|M9PBM9|M9PBM9_DROME
Uncharacterized protein, isoform A
Search

0.39	GO:0016570	histone modification
0.39	GO:0018205	peptidyl-lysine modification
0.38	GO:1904263	positive regulation of TORC1 signaling
0.38	GO:0016236	macroautophagy
0.37	GO:0090114	COPII-coated vesicle budding
0.37	GO:0006475	internal protein amino acid acetylation
0.37	GO:0007155	cell adhesion
0.36	GO:0001522	pseudouridine synthesis
0.36	GO:0008213	protein alkylation
0.36	GO:0006397	mRNA processing

0.44	GO:0003676	nucleic acid binding
0.38	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.38	GO:0043130	ubiquitin binding
0.38	GO:0004402	histone acetyltransferase activity
0.37	GO:0005198	structural molecule activity
0.37	GO:0031177	phosphopantetheine binding
0.36	GO:0009982	pseudouridine synthase activity
0.36	GO:0046872	metal ion binding
0.36	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups

0.38	GO:0044451	nucleoplasm part
0.38	GO:0005581	collagen trimer
0.38	GO:1990234	transferase complex
0.37	GO:0031012	extracellular matrix
0.37	GO:0030127	COPII vesicle coat
0.36	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.38

GO:0004402

tr|M9PBN2|M9PBN2_DROME
Neural lazarillo, isoform B
Search

0.53	Neural Lazarillo

0.71	GO:0070328	triglyceride homeostasis
0.70	GO:0008340	determination of adult lifespan
0.67	GO:0033500	carbohydrate homeostasis
0.60	GO:0006979	response to oxidative stress
0.47	GO:0032504	multicellular organism reproduction
0.38	GO:0006869	lipid transport
0.34	GO:0052200	response to host defenses
0.34	GO:0051807	evasion or tolerance of defense response of other organism involved in symbiotic interaction

0.85	GO:0031409	pigment binding
0.38	GO:0008289	lipid binding

0.61	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

tr|M9PBN5|M9PBN5_DROME
Uncharacterized protein
Search

tr|M9PBR0|M9PBR0_DROME
Blimp-1, isoform B
Search

BLIMP-1

0.34	Blimp-1, isoform B

0.56	GO:0035074	pupation
0.54	GO:0071390	cellular response to ecdysone
0.53	GO:0035152	regulation of tube architecture, open tracheal system
0.51	GO:0000122	negative regulation of transcription by RNA polymerase II
0.38	GO:1990654	sebum secreting cell proliferation
0.38	GO:0033082	regulation of extrathymic T cell differentiation
0.38	GO:0051136	regulation of NK T cell differentiation
0.38	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway
0.38	GO:0060576	intestinal epithelial cell development
0.38	GO:0032823	regulation of natural killer cell differentiation

0.53	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0003676	nucleic acid binding
0.37	GO:1990841	promoter-specific chromatin binding
0.37	GO:0042826	histone deacetylase binding
0.33	GO:0042302	structural constituent of cuticle

0.43	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm

tr|M9PBR6|M9PBR6_DROME
Uncharacterized protein, isoform F
Search

0.64	LOW QUALITY PROTEIN: motile sperm domain-containing protein 2

0.34	GO:0019464	glycine decarboxylation via glycine cleavage system
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.31	GO:0009059	macromolecule biosynthetic process

0.33	GO:0016746	transferase activity, transferring acyl groups
0.32	GO:0003676	nucleic acid binding
0.32	GO:0003735	structural constituent of ribosome

0.45	GO:0012505	endomembrane system
0.41	GO:0005856	cytoskeleton
0.35	GO:0005960	glycine cleavage complex
0.33	GO:0031984	organelle subcompartment
0.32	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.33

EC:2.3

GO:0016746

tr|M9PBT0|M9PBT0_DROME
Uncharacterized protein
Search

tr|M9PBV2|M9PBV2_DROME
NTPase, isoform F
Search

0.61	Ectonucleoside triphosphate diphosphohydrolase 5 precursor

0.35	GO:0046048	UDP metabolic process
0.34	GO:0046710	GDP metabolic process
0.33	GO:0006487	protein N-linked glycosylation
0.32	GO:0055085	transmembrane transport

0.53	GO:0045134	uridine-diphosphatase activity
0.52	GO:0004382	guanosine-diphosphatase activity
0.32	GO:0022857	transmembrane transporter activity
0.32	GO:0046872	metal ion binding

0.37	GO:0005737	cytoplasm
0.34	GO:0012505	endomembrane system
0.33	GO:0043227	membrane-bounded organelle
0.33	GO:0043229	intracellular organelle
0.33	GO:0044422	organelle part
0.32	GO:0031974	membrane-enclosed lumen
0.30	GO:0016020	membrane

0.53	EC:3.6.1.6	GO:0045134
0.53	KEGG:R00155	GO:0045134

tr|M9PBV9|M9PBV9_DROME
Uncharacterized protein
Search

tr|M9PBX3|M9PBX3_DROME
Uncharacterized protein, isoform H
Search

0.21	Abc transporter

0.39	GO:0030301	cholesterol transport
0.34	GO:0015716	organic phosphonate transport
0.34	GO:0015748	organophosphate ester transport
0.34	GO:0099133	ATP hydrolysis coupled anion transmembrane transport
0.33	GO:0055085	transmembrane transport

0.61	GO:0016887	ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0017127	cholesterol transporter activity
0.38	GO:1901618	organic hydroxy compound transmembrane transporter activity
0.37	GO:0015399	primary active transmembrane transporter activity
0.34	GO:0015604	organic phosphonate transmembrane transporter activity
0.34	GO:0015605	organophosphate ester transmembrane transporter activity

0.35	GO:0005886	plasma membrane
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.61

GO:0016887

tr|M9PBZ2|M9PBZ2_DROME
RNA-binding protein 9, isoform J
Search

0.20	RNA-binding protein 9, isoform J

0.55	GO:0036093	germ cell proliferation
0.53	GO:0060856	establishment of blood-brain barrier
0.50	GO:0048477	oogenesis
0.42	GO:0008049	male courtship behavior
0.40	GO:0048646	anatomical structure formation involved in morphogenesis
0.40	GO:0050684	regulation of mRNA processing

0.59

GO:0003723

RNA binding

0.37	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm

tr|M9PBZ7|M9PBZ7_DROME
Uncharacterized protein
Search

0.42	GO:0006030	chitin metabolic process
0.38	GO:0006508	proteolysis
0.38	GO:0007160	cell-matrix adhesion
0.37	GO:0006338	chromatin remodeling
0.37	GO:0032501	multicellular organismal process
0.36	GO:0005975	carbohydrate metabolic process
0.36	GO:0035725	sodium ion transmembrane transport
0.35	GO:0048856	anatomical structure development
0.35	GO:0009057	macromolecule catabolic process
0.35	GO:0030154	cell differentiation

0.46	GO:0030246	carbohydrate binding
0.45	GO:0008061	chitin binding
0.39	GO:0052689	carboxylic ester hydrolase activity
0.38	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.38	GO:0005509	calcium ion binding
0.38	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.37	GO:0008270	zinc ion binding
0.37	GO:0017171	serine hydrolase activity
0.36	GO:0005272	sodium channel activity
0.36	GO:0005201	extracellular matrix structural constituent

0.46	GO:0005576	extracellular region
0.37	GO:0070603	SWI/SNF superfamily-type complex
0.36	GO:0005618	cell wall
0.34	GO:0000145	exocyst
0.34	GO:0035869	ciliary transition zone
0.34	GO:1990234	transferase complex
0.33	GO:0090575	RNA polymerase II transcription factor complex
0.33	GO:0005886	plasma membrane
0.33	GO:0044451	nucleoplasm part
0.32	GO:0098533	ATPase dependent transmembrane transport complex

0.39	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.39	KEGG:R00630	GO:0052689

tr|M9PC26|M9PC26_DROME
Uncharacterized protein, isoform E
Search

0.55

GO:0016310

phosphorylation

0.57

GO:0016301

kinase activity

0.30

GO:0044425

membrane part

tr|M9PC42|M9PC42_DROME
Uncharacterized protein, isoform A
Search

0.56	histidine-rich glycoprotein

0.48	GO:0016236	macroautophagy
0.46	GO:0043044	ATP-dependent chromatin remodeling
0.38	GO:0000395	mRNA 5'-splice site recognition
0.38	GO:0006357	regulation of transcription by RNA polymerase II
0.38	GO:0048519	negative regulation of biological process
0.38	GO:0051336	regulation of hydrolase activity
0.37	GO:0000387	spliceosomal snRNP assembly
0.37	GO:0009966	regulation of signal transduction
0.36	GO:0043086	negative regulation of catalytic activity
0.36	GO:0048246	macrophage chemotaxis

0.48	GO:0043130	ubiquitin binding
0.44	GO:0008270	zinc ion binding
0.41	GO:0003723	RNA binding
0.38	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.38	GO:0098772	molecular function regulator
0.38	GO:0003677	DNA binding
0.37	GO:0030246	carbohydrate binding
0.36	GO:0019863	IgE binding
0.36	GO:0043236	laminin binding
0.36	GO:0004672	protein kinase activity

0.46	GO:0016514	SWI/SNF complex
0.40	GO:0019867	outer membrane
0.38	GO:0000243	commitment complex
0.38	GO:0071004	U2-type prespliceosome
0.38	GO:0005685	U1 snRNP
0.37	GO:0031251	PAN complex
0.36	GO:0001772	immunological synapse
0.35	GO:0030428	cell septum
0.35	GO:0031012	extracellular matrix
0.33	GO:0031966	mitochondrial membrane

0.35

EC:2.3.2.4

GO:0003839

tr|M9PC46|M9PC46_DROME
Roundabout 2, isoform B
Search

ROBO2

0.65	Roundabout 2

0.83	GO:0042685	cardioblast cell fate specification
0.80	GO:0007432	salivary gland boundary specification
0.79	GO:0048036	central complex development
0.79	GO:2000274	regulation of epithelial cell migration, open tracheal system
0.77	GO:0007419	ventral cord development
0.76	GO:0008039	synaptic target recognition
0.75	GO:0016319	mushroom body development
0.74	GO:0003151	outflow tract morphogenesis
0.73	GO:0035050	embryonic heart tube development
0.72	GO:0001764	neuron migration

0.65	GO:0042803	protein homodimerization activity
0.45	GO:0004872	receptor activity
0.35	GO:0008201	heparin binding

0.69	GO:0030424	axon
0.36	GO:0071666	Slit-Robo signaling complex
0.35	GO:0030426	growth cone
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.34	GO:0031982	vesicle
0.33	GO:0043234	protein complex
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|M9PC53|M9PC53_DROME
Uncharacterized protein, isoform A
Search

tr|M9PC61|M9PC61_DROME
Uncharacterized protein, isoform C
Search

0.20	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

0.46	GO:0016310	phosphorylation
0.46	GO:0043043	peptide biosynthetic process
0.44	GO:0044267	cellular protein metabolic process
0.43	GO:0010467	gene expression
0.42	GO:0009059	macromolecule biosynthetic process

0.48	GO:0003735	structural constituent of ribosome
0.47	GO:0016301	kinase activity
0.42	GO:0016853	isomerase activity

0.47	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.42

GO:0016853

tr|M9PC68|M9PC68_DROME
CG6175, isoform D
Search

0.11	homeobox protein cut

0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.34	GO:1905499	trichome papilla formation
0.34	GO:0010091	trichome branching
0.34	GO:0009911	positive regulation of flower development
0.34	GO:0034220	ion transmembrane transport
0.34	GO:0010114	response to red light
0.34	GO:0010218	response to far red light

0.54	GO:0003677	DNA binding
0.35	GO:0005216	ion channel activity
0.34	GO:0003713	transcription coactivator activity
0.34	GO:0004491	methylmalonate-semialdehyde dehydrogenase (acylating) activity
0.33	GO:0046983	protein dimerization activity
0.33	GO:0004402	histone acetyltransferase activity
0.32	GO:0008270	zinc ion binding

0.61	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0008540	proteasome regulatory particle, base subcomplex
0.33	GO:0031248	protein acetyltransferase complex
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.34

EC:1.2.1.27

GO:0004491

tr|M9PC80|M9PC80_DROME
Dynein, axonemal, intermediate chain 2, isoform C
Search

0.73	Axonemal outer arm dynein intermediate chain 1

0.85	GO:0036158	outer dynein arm assembly
0.78	GO:0046692	sperm competition
0.76	GO:0010996	response to auditory stimulus
0.71	GO:0007605	sensory perception of sound
0.61	GO:0003341	cilium movement
0.51	GO:0007368	determination of left/right symmetry
0.35	GO:0007186	G-protein coupled receptor signaling pathway

0.58	GO:0045504	dynein heavy chain binding
0.58	GO:0045503	dynein light chain binding
0.57	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed
0.38	GO:0008017	microtubule binding
0.37	GO:0003723	RNA binding
0.35	GO:0004930	G-protein coupled receptor activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0120038	plasma membrane bounded cell projection part
0.70	GO:0043025	neuronal cell body
0.70	GO:0097447	dendritic tree
0.59	GO:0030286	dynein complex
0.58	GO:0005929	cilium
0.56	GO:0099568	cytoplasmic region
0.51	GO:0097223	sperm part
0.50	GO:0009897	external side of plasma membrane
0.36	GO:0005874	microtubule
0.30	GO:0016021	integral component of membrane

0.57

EC:3.6.4.4

GO:0008574

tr|M9PC99|M9PC99_DROME
Sec24CD ortholog, isoform C
Search

0.91	Putative vesicle coat complex copii subunit sec24/subunit sfb2

0.78	GO:0006888	ER to Golgi vesicle-mediated transport
0.69	GO:0006886	intracellular protein transport
0.52	GO:0048081	positive regulation of cuticle pigmentation
0.51	GO:0003331	positive regulation of extracellular matrix constituent secretion
0.51	GO:0035158	regulation of tube diameter, open tracheal system
0.50	GO:0035149	lumen formation, open tracheal system
0.50	GO:0016203	muscle attachment
0.49	GO:0034394	protein localization to cell surface
0.49	GO:0071711	basement membrane organization
0.49	GO:0040003	chitin-based cuticle development

0.63	GO:0008270	zinc ion binding
0.34	GO:0070403	NAD+ binding
0.34	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0030127	COPII vesicle coat
0.49	GO:0070971	endoplasmic reticulum exit site
0.37	GO:0000139	Golgi membrane
0.34	GO:0034464	BBSome
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.4.19.12

GO:0036459

tr|M9PCB0|M9PCB0_DROME
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|M9PCB8|M9PCB8_DROME
Uncharacterized protein, isoform C
Search

0.69	GO:0010923	negative regulation of phosphatase activity
0.49	GO:0010469	regulation of receptor activity
0.42	GO:0099120	socially cooperative development
0.41	GO:0006368	transcription elongation from RNA polymerase II promoter
0.40	GO:0035023	regulation of Rho protein signal transduction
0.40	GO:0016570	histone modification
0.37	GO:0006468	protein phosphorylation
0.37	GO:0035556	intracellular signal transduction

0.50	GO:0008083	growth factor activity
0.40	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.39	GO:0004674	protein serine/threonine kinase activity
0.38	GO:0032550	purine ribonucleoside binding
0.38	GO:0019001	guanyl nucleotide binding
0.37	GO:0004871	signal transducer activity
0.35	GO:0003677	DNA binding
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0032555	purine ribonucleotide binding
0.35	GO:0008144	drug binding

0.45	GO:0005576	extracellular region
0.41	GO:0016593	Cdc73/Paf1 complex
0.36	GO:0005886	plasma membrane
0.34	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.39

GO:0004674

tr|M9PCB9|M9PCB9_DROME
Uncharacterized protein, isoform A
Search

tr|M9PCC8|M9PCC8_DROME
Uncharacterized protein, isoform D
Search

tr|M9PCC9|M9PCC9_DROME
Uncharacterized protein
Search

tr|M9PCD4|M9PCD4_DROME
Liprin-alpha, isoform E
Search

0.75	Liprin-alpha

0.81	GO:0050808	synapse organization
0.57	GO:0045467	R7 cell development
0.56	GO:0007412	axon target recognition
0.56	GO:0008594	photoreceptor cell morphogenesis
0.56	GO:0048490	anterograde synaptic vesicle transport
0.55	GO:0048841	regulation of axon extension involved in axon guidance
0.55	GO:0031290	retinal ganglion cell axon guidance
0.54	GO:0048675	axon extension
0.45	GO:0022607	cellular component assembly

0.38	GO:0005515	protein binding
0.31	GO:1901265	nucleoside phosphate binding
0.31	GO:0036094	small molecule binding

0.75	GO:0045202	synapse
0.54	GO:1904115	axon cytoplasm
0.52	GO:0005925	focal adhesion
0.43	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

tr|M9PCE3|M9PCE3_DROME
Uncharacterized protein, isoform D
Search

LOC108088150

0.32	Sodium/hydrogen exchanger

0.74	GO:0010506	regulation of autophagy
0.38	GO:0006885	regulation of pH
0.37	GO:0035725	sodium ion transmembrane transport
0.35	GO:1902600	hydrogen ion transmembrane transport
0.35	GO:0006468	protein phosphorylation

0.44	GO:0004419	hydroxymethylglutaryl-CoA lyase activity
0.38	GO:0015385	sodium:proton antiporter activity
0.35	GO:0004672	protein kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

0.73	GO:0005615	extracellular space
0.41	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.44	EC:4.1.3.4	GO:0004419
0.44	KEGG:R01360	GO:0004419

tr|M9PCE9|M9PCE9_DROME
Ral guanine nucleotide dissociation stimulator-like, isoform E
Search

0.70	Ral guanine nucleotide dissociation stimulator 1

0.76	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.43	GO:0046578	regulation of Ras protein signal transduction

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.65	GO:0017160	Ral GTPase binding
0.33	GO:0003779	actin binding

0.45	GO:0005622	intracellular
0.30	GO:0044425	membrane part

tr|M9PCF9|M9PCF9_DROME
CG9541, isoform D
Search

0.18	Uridylate kinase

0.57	GO:0016310	phosphorylation
0.49	GO:1901360	organic cyclic compound metabolic process
0.49	GO:0046483	heterocycle metabolic process
0.49	GO:0006725	cellular aromatic compound metabolic process
0.45	GO:0006807	nitrogen compound metabolic process
0.34	GO:0090407	organophosphate biosynthetic process
0.33	GO:0044281	small molecule metabolic process
0.33	GO:0044249	cellular biosynthetic process
0.32	GO:0043094	cellular metabolic compound salvage
0.32	GO:1901137	carbohydrate derivative biosynthetic process

0.72	GO:0019205	nucleobase-containing compound kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0016776	phosphotransferase activity, phosphate group as acceptor

0.34	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.35

EC:2.7.4

GO:0016776

tr|M9PCG2|M9PCG2_DROME
Sox21b, isoform C
Search

0.75	transcription factor SOX-8

0.43	GO:0048731	system development
0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.42	GO:0010468	regulation of gene expression
0.42	GO:0022405	hair cycle process
0.42	GO:0048863	stem cell differentiation
0.41	GO:0008544	epidermis development
0.40	GO:0006366	transcription by RNA polymerase II
0.40	GO:0060429	epithelium development
0.40	GO:1902680	positive regulation of RNA biosynthetic process

0.55	GO:0003677	DNA binding
0.42	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0001067	regulatory region nucleic acid binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.33	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

tr|M9PCG3|M9PCG3_DROME
Zizimin ortholog, isoform K
Search

ZIZ

0.75	Dedicator of cytokinesis protein 9

0.77	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.44	GO:0035023	regulation of Rho protein signal transduction

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.44	GO:0017048	Rho GTPase binding
0.32	GO:0008270	zinc ion binding

0.45

GO:0005622

intracellular

tr|M9PCH1|M9PCH1_DROME
Uncharacterized protein, isoform A
Search

0.10	kunitz-type U1-aranetoxin-Av1a

0.76

GO:0010951

negative regulation of endopeptidase activity

0.79

GO:0004867

serine-type endopeptidase inhibitor activity

tr|M9PCH5|M9PCH5_DROME
Uncharacterized protein, isoform D
Search

0.43

GO:0006468

protein phosphorylation

0.45	GO:0004674	protein serine/threonine kinase activity
0.39	GO:0030554	adenyl nucleotide binding
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding

0.45

GO:0004674

tr|M9PCH7|M9PCH7_DROME
Uncharacterized protein
Search

tr|M9PCI1|M9PCI1_DROME
Uncharacterized protein, isoform B
Search

0.33	GO:0035335	peptidyl-tyrosine dephosphorylation
0.33	GO:0050482	arachidonic acid secretion
0.32	GO:0006030	chitin metabolic process
0.32	GO:0000272	polysaccharide catabolic process
0.32	GO:0006644	phospholipid metabolic process
0.32	GO:0032259	methylation
0.32	GO:0060255	regulation of macromolecule metabolic process

0.34	GO:0005509	calcium ion binding
0.33	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0008061	chitin binding
0.33	GO:0030246	carbohydrate binding
0.33	GO:0004623	phospholipase A2 activity
0.33	GO:0003682	chromatin binding
0.32	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.32	GO:0008168	methyltransferase activity

0.33	GO:0070701	mucus layer
0.30	GO:0016020	membrane

0.33

GO:0004725

tr|M9PCI3|M9PCI3_DROME
Uncharacterized protein
Search

0.76	GO:0010951	negative regulation of endopeptidase activity
0.51	GO:0009617	response to bacterium

0.79

GO:0004867

serine-type endopeptidase inhibitor activity

tr|M9PCI9|M9PCI9_DROME
Uncharacterized protein
Search

tr|M9PCK0|M9PCK0_DROME
Uncharacterized protein, isoform D
Search

0.10	Regulator of G-protein signaling 7-binding protein

0.51	GO:0016192	vesicle-mediated transport
0.38	GO:0006869	lipid transport
0.37	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.37	GO:0006754	ATP biosynthetic process
0.37	GO:0099132	ATP hydrolysis coupled cation transmembrane transport

0.37

GO:0046933

proton-transporting ATP synthase activity, rotational mechanism

0.30

GO:0031224

intrinsic component of membrane

tr|M9PCM2|M9PCM2_DROME
Uncharacterized protein, isoform B
Search

0.10	Fibronectin-attachment protein (FAP) (Fragment)

0.55

GO:0009890

negative regulation of biosynthetic process

0.62

GO:0005509

calcium ion binding

0.30

GO:0044425

membrane part

tr|M9PCP3|M9PCP3_DROME
CG9044, isoform C
Search

LOC108088132

0.49	serine/threonine-protein kinase 11-interacting protein isoform X1

0.54	GO:0016310	phosphorylation
0.48	GO:0008104	protein localization

0.56	GO:0016301	kinase activity
0.55	GO:0019901	protein kinase binding
0.36	GO:0003676	nucleic acid binding
0.33	GO:0008484	sulfuric ester hydrolase activity

0.40	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.1.6

GO:0008484

tr|M9PCR1|M9PCR1_DROME
Uncharacterized protein, isoform C
Search

tr|M9PCS7|M9PCS7_DROME
Uncharacterized protein
Search

tr|M9PCT4|M9PCT4_DROME
Ionotropic receptor 31a, isoform C
Search

IR31A

0.70	glutamate receptor ionotropic, kainate 5

0.71	GO:0035235	ionotropic glutamate receptor signaling pathway
0.61	GO:0050907	detection of chemical stimulus involved in sensory perception
0.38	GO:0055085	transmembrane transport
0.35	GO:0070084	protein initiator methionine removal
0.33	GO:0006508	proteolysis

0.72	GO:0004970	ionotropic glutamate receptor activity
0.35	GO:0070006	metalloaminopeptidase activity
0.33	GO:0046872	metal ion binding

0.30

GO:0031224

intrinsic component of membrane

tr|M9PCT6|M9PCT6_DROME
Uncharacterized protein
Search

0.53

GO:0006030

chitin metabolic process

0.56

GO:0008061

chitin binding

0.48

GO:0005576

extracellular region

tr|M9PCU5|M9PCU5_DROME
Lipase 4, isoform C
Search

0.44	Alpha/beta-hydrolase lipase region

0.60	GO:0016042	lipid catabolic process
0.33	GO:0032504	multicellular organism reproduction

0.58	GO:0016788	hydrolase activity, acting on ester bonds
0.32	GO:0003677	DNA binding

0.33	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.58

GO:0016788

tr|M9PCW4|M9PCW4_DROME
Uncharacterized protein, isoform B
Search

tr|M9PCX5|M9PCX5_DROME
Uncharacterized protein, isoform B
Search

0.34	GO:0060079	excitatory postsynaptic potential
0.33	GO:0034220	ion transmembrane transport

0.35	GO:0022848	acetylcholine-gated cation-selective channel activity
0.34	GO:0099600	transmembrane receptor activity

0.71	GO:0005730	nucleolus
0.43	GO:0005654	nucleoplasm
0.40	GO:0005829	cytosol
0.34	GO:0045211	postsynaptic membrane
0.34	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

tr|M9PCY6|M9PCY6_DROME
Uncharacterized protein
Search

0.86	GO:0045572	positive regulation of imaginal disc growth
0.85	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.85	GO:0042067	establishment of ommatidial planar polarity
0.84	GO:0035218	leg disc development
0.51	GO:0007018	microtubule-based movement
0.45	GO:0035332	positive regulation of hippo signaling
0.45	GO:0090251	protein localization involved in establishment of planar polarity

0.75	GO:0051015	actin filament binding
0.54	GO:0000146	microfilament motor activity
0.51	GO:0003777	microtubule motor activity
0.51	GO:0032947	protein complex scaffold activity
0.51	GO:0008017	microtubule binding
0.43	GO:0016887	ATPase activity
0.42	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0016459	myosin complex
0.48	GO:0005737	cytoplasm
0.44	GO:0016327	apicolateral plasma membrane

0.43

GO:0016887

tr|M9PCZ4|M9PCZ4_DROME
Uncharacterized protein
Search

tr|M9PCZ5|M9PCZ5_DROME
Uncharacterized protein
Search

tr|M9PCZ7|M9PCZ7_DROME
SoxNeuro, isoform B
Search

0.35	LOW QUALITY PROTEIN: GATA zinc finger domain-containing protein 10

0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0007399	nervous system development
0.55	GO:0010468	regulation of gene expression
0.51	GO:0035293	chitin-based larval cuticle pattern formation
0.50	GO:0007367	segment polarity determination
0.50	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.50	GO:0000904	cell morphogenesis involved in differentiation
0.49	GO:0120036	plasma membrane bounded cell projection organization
0.48	GO:0090090	negative regulation of canonical Wnt signaling pathway

0.55	GO:0003677	DNA binding
0.52	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.49	GO:0003682	chromatin binding
0.39	GO:0005515	protein binding
0.35	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0001067	regulatory region nucleic acid binding
0.33	GO:0070001	aspartic-type peptidase activity
0.32	GO:0004175	endopeptidase activity
0.32	GO:0008270	zinc ion binding

0.61	GO:0005634	nucleus
0.33	GO:0005667	transcription factor complex
0.30	GO:0031224	intrinsic component of membrane

tr|M9PCZ8|M9PCZ8_DROME
Uncharacterized protein, isoform A
Search

0.86	male-specific sperm protein Mst84Dc

tr|M9PD03|M9PD03_DROME
CG9586, isoform C
Search

0.52	coiled-coil domain-containing protein 43

0.55	GO:0016829	lyase activity
0.45	GO:0003723	RNA binding
0.37	GO:0016787	hydrolase activity

0.55

EC:4

GO:0016829

tr|M9PD06|M9PD06_DROME
Ubiquitin specific protease 32, isoform B
Search

0.66	Ubiquitin carboxyl-terminal hydrolase 32

0.76	GO:0016579	protein deubiquitination
0.71	GO:0006511	ubiquitin-dependent protein catabolic process

0.76	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.67	GO:0005509	calcium ion binding

tr|M9PD12|M9PD12_DROME
Spichthyin, isoform B
Search

0.84	Non imprinted in Prader-Willi/Angelman syndrome 2 (human)

0.77	GO:1903830	magnesium ion transmembrane transport
0.53	GO:0048687	positive regulation of sprouting of injured axon
0.53	GO:0048690	regulation of axon extension involved in regeneration
0.53	GO:0045886	negative regulation of synaptic growth at neuromuscular junction
0.51	GO:0030514	negative regulation of BMP signaling pathway
0.51	GO:0045773	positive regulation of axon extension
0.41	GO:0008344	adult locomotory behavior
0.33	GO:0016192	vesicle-mediated transport

0.78

GO:0015095

magnesium ion transmembrane transporter activity

0.40	GO:0043025	neuronal cell body
0.36	GO:0005769	early endosome
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|M9PD23|M9PD23_DROME
DnaJ homolog, isoform C
Search

DNAJA2

0.47	Molecular chaperone

0.69	GO:0006457	protein folding
0.61	GO:0009408	response to heat
0.47	GO:0032781	positive regulation of ATPase activity
0.35	GO:0018885	carbon tetrachloride metabolic process
0.34	GO:2000312	regulation of kainate selective glutamate receptor activity
0.34	GO:0006508	proteolysis
0.34	GO:0008284	positive regulation of cell proliferation
0.33	GO:0035966	response to topologically incorrect protein
0.32	GO:0006260	DNA replication

0.77	GO:0031072	heat shock protein binding
0.71	GO:0051082	unfolded protein binding
0.53	GO:0046872	metal ion binding
0.47	GO:0001671	ATPase activator activity
0.47	GO:0032559	adenyl ribonucleotide binding
0.46	GO:0008144	drug binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0051087	chaperone binding
0.35	GO:0004177	aminopeptidase activity
0.32	GO:0003677	DNA binding

0.45	GO:0005829	cytosol
0.35	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.35

EC:3.4.11

GO:0004177

tr|M9PD30|M9PD30_DROME
CG5850, isoform G
Search

0.57	Organic solute transporter ostalpha

0.33	GO:0051567	histone H3-K9 methylation
0.33	GO:0006457	protein folding
0.33	GO:0006231	dTMP biosynthetic process
0.33	GO:0048477	oogenesis
0.32	GO:0006357	regulation of transcription by RNA polymerase II

0.35	GO:0005215	transporter activity
0.33	GO:0051082	unfolded protein binding
0.33	GO:0043035	chromatin insulator sequence binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0004799	thymidylate synthase activity

0.33	GO:0005783	endoplasmic reticulum
0.33	GO:0005705	polytene chromosome interband
0.33	GO:0000790	nuclear chromatin
0.30	GO:0016020	membrane

0.33	EC:2.1.1.45	GO:0004799
0.33	KEGG:R02101	GO:0004799

tr|M9PD53|M9PD53_DROME
Lim3, isoform G
Search

0.62	LIM homeodomain transcription factor

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0008045	motor neuron axon guidance
0.56	GO:0010468	regulation of gene expression
0.45	GO:0021526	medial motor column neuron differentiation
0.44	GO:0021521	ventral spinal cord interneuron specification
0.44	GO:0021527	spinal cord association neuron differentiation
0.43	GO:0021520	spinal cord motor neuron cell fate specification
0.43	GO:0021983	pituitary gland development
0.42	GO:0048839	inner ear development

0.64	GO:0043565	sequence-specific DNA binding
0.54	GO:0046872	metal ion binding
0.43	GO:0001085	RNA polymerase II transcription factor binding
0.42	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.41	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.41	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.40	GO:0001012	RNA polymerase II regulatory region DNA binding
0.39	GO:0003690	double-stranded DNA binding
0.32	GO:0016740	transferase activity

0.61	GO:0005634	nucleus
0.40	GO:0005667	transcription factor complex
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.32

GO:0016740

tr|M9PD66|M9PD66_DROME
Uncharacterized protein
Search

tr|M9PD67|M9PD67_DROME
Uncharacterized protein, isoform C
Search

0.63

GO:0006468

protein phosphorylation

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

tr|M9PD70|M9PD70_DROME
Alkaline phosphatase 1, isoform B
Search

0.44	alkaline phosphatase

0.68	GO:0016311	dephosphorylation
0.43	GO:0035094	response to nicotine
0.41	GO:0001666	response to hypoxia
0.32	GO:0007165	signal transduction

0.77	GO:0004035	alkaline phosphatase activity
0.33	GO:0005509	calcium ion binding

0.39	GO:0009986	cell surface
0.33	GO:0005578	proteinaceous extracellular matrix
0.33	GO:0031225	anchored component of membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.77

EC:3.1.3.1

GO:0004035

tr|M9PD84|M9PD84_DROME
Ca2+-channel-protein-beta-subunit, isoform L
Search

0.62	Voltage-dependent L-type calcium channel subunit beta-2

0.77	GO:0070588	calcium ion transmembrane transport
0.51	GO:0016322	neuron remodeling
0.49	GO:0019722	calcium-mediated signaling
0.37	GO:1901385	regulation of voltage-gated calcium channel activity
0.36	GO:0007528	neuromuscular junction development
0.36	GO:0007268	chemical synaptic transmission
0.32	GO:0016310	phosphorylation

0.82	GO:0005245	voltage-gated calcium channel activity
0.32	GO:0016301	kinase activity

0.81	GO:0005891	voltage-gated calcium channel complex
0.36	GO:0005622	intracellular

tr|M9PD88|M9PD88_DROME
Antioxidant 1 copper chaperone, isoform B
Search

0.41	Heavy metal transporter

0.66	GO:0030001	metal ion transport
0.58	GO:0055070	copper ion homeostasis
0.40	GO:0046916	cellular transition metal ion homeostasis
0.39	GO:0006979	response to oxidative stress
0.38	GO:0046907	intracellular transport

0.54	GO:0046872	metal ion binding
0.42	GO:0016530	metallochaperone activity

0.34

GO:0005737

cytoplasm

tr|M9PD96|M9PD96_DROME
Uncharacterized protein
Search

tr|M9PDC4|M9PDC4_DROME
Misexpression suppressor of ras 3, isoform B
Search

MESR3

0.39	Misexpression suppressor of ras 3

0.84

GO:0046580

negative regulation of Ras protein signal transduction

tr|M9PDC8|M9PDC8_DROME
Uncharacterized protein
Search

tr|M9PDD8|M9PDD8_DROME
Uncharacterized protein, isoform D
Search

LOC108092919

0.92	Cuticular protein PpolCPG15

0.35	GO:0006369	termination of RNA polymerase II transcription
0.35	GO:0032784	regulation of DNA-templated transcription, elongation
0.34	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0001172	transcription, RNA-templated
0.34	GO:0006364	rRNA processing
0.33	GO:0008033	tRNA processing
0.33	GO:0032259	methylation

0.37	GO:0003723	RNA binding
0.36	GO:0000991	transcription factor activity, core RNA polymerase II binding
0.35	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.35	GO:0046983	protein dimerization activity
0.34	GO:0003677	DNA binding
0.34	GO:0003968	RNA-directed 5'-3' RNA polymerase activity
0.33	GO:0008168	methyltransferase activity

0.36	GO:0019013	viral nucleocapsid
0.35	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0000428	DNA-directed RNA polymerase complex
0.34	GO:0000785	chromatin
0.30	GO:0016020	membrane

0.35

GO:0003899

tr|M9PDE6|M9PDE6_DROME
Uncharacterized protein, isoform K
Search

0.34	GO:0016567	protein ubiquitination
0.33	GO:0016310	phosphorylation

0.85	GO:0008157	protein phosphatase 1 binding
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0016301	kinase activity

0.72

GO:0016328

lateral plasma membrane

0.34

GO:0004842

tr|M9PDE7|M9PDE7_DROME
Uncharacterized protein, isoform O
Search

0.77	GO:0043410	positive regulation of MAPK cascade
0.41	GO:0051568	histone H3-K4 methylation
0.34	GO:0006413	translational initiation

0.85	GO:0005078	MAP-kinase scaffold activity
0.39	GO:0045322	unmethylated CpG binding
0.38	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.36	GO:0046872	metal ion binding
0.34	GO:0003743	translation initiation factor activity

0.41	GO:0035097	histone methyltransferase complex
0.30	GO:0016020	membrane

tr|M9PDI0|M9PDI0_DROME
Midkine and pleiotrophin 2, isoform D
Search

MIPLE2

0.92	Midkine and pleiotrophin 2, isoform D

0.76	GO:0010469	regulation of receptor activity
0.67	GO:0008340	determination of adult lifespan
0.50	GO:0048332	mesoderm morphogenesis
0.32	GO:0008610	lipid biosynthetic process
0.32	GO:0055114	oxidation-reduction process

0.78	GO:0008083	growth factor activity
0.66	GO:0008201	heparin binding
0.32	GO:0003676	nucleic acid binding
0.32	GO:0005506	iron ion binding
0.32	GO:0016491	oxidoreductase activity

0.55	GO:0005576	extracellular region
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016491

tr|M9PDL5|M9PDL5_DROME
Uncharacterized protein
Search

0.51	GO:0006812	cation transport
0.50	GO:0034220	ion transmembrane transport
0.44	GO:0006461	protein complex assembly
0.37	GO:0099131	ATP hydrolysis coupled ion transmembrane transport
0.37	GO:0022900	electron transport chain
0.37	GO:2000274	regulation of epithelial cell migration, open tracheal system
0.37	GO:0006357	regulation of transcription by RNA polymerase II
0.37	GO:0010312	detoxification of zinc ion
0.37	GO:0065009	regulation of molecular function
0.36	GO:0042069	regulation of catecholamine metabolic process

0.52	GO:0008324	cation transmembrane transporter activity
0.46	GO:0016151	nickel cation binding
0.43	GO:0015318	inorganic molecular entity transmembrane transporter activity
0.42	GO:0042302	structural constituent of cuticle
0.40	GO:0003924	GTPase activity
0.38	GO:0042625	ATPase coupled ion transmembrane transporter activity
0.37	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.37	GO:0098772	molecular function regulator
0.36	GO:0005549	odorant binding
0.36	GO:0030554	adenyl nucleotide binding

0.41	GO:0005886	plasma membrane
0.37	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0005615	extracellular space
0.36	GO:0008021	synaptic vesicle
0.36	GO:0043025	neuronal cell body
0.36	GO:0034705	potassium channel complex
0.35	GO:0030424	axon
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0044446	intracellular organelle part
0.35	GO:0031975	envelope

0.36

GO:0016676

tr|M9PDM4|M9PDM4_DROME
Phosphatidylinositol 4-kinase III alpha, isoform D
Search

0.66	Phosphatidylinositol 4-kinase alpha

0.81	GO:0048015	phosphatidylinositol-mediated signaling
0.75	GO:0046854	phosphatidylinositol phosphorylation
0.53	GO:0071711	basement membrane organization
0.53	GO:0007293	germarium-derived egg chamber formation
0.53	GO:0008582	regulation of synaptic growth at neuromuscular junction
0.52	GO:0035329	hippo signaling
0.52	GO:0048599	oocyte development
0.51	GO:0007009	plasma membrane organization
0.51	GO:0030010	establishment of cell polarity
0.49	GO:0030036	actin cytoskeleton organization

0.60	GO:0016301	kinase activity
0.39	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.36	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.35	GO:0018024	histone-lysine N-methyltransferase activity
0.34	GO:0045296	cadherin binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005622	intracellular
0.36	GO:0005886	plasma membrane
0.35	GO:0019034	viral replication complex
0.30	GO:0016021	integral component of membrane

0.39

GO:0016773

tr|M9PDN5|M9PDN5_DROME
Uncharacterized protein
Search

tr|M9PDP1|M9PDP1_DROME
Uncharacterized protein, isoform B
Search

0.72	Membrane associated ring-CH-type finger 5

0.48	GO:0000209	protein polyubiquitination
0.45	GO:0090140	regulation of mitochondrial fission
0.45	GO:0090344	negative regulation of cell aging
0.44	GO:0051865	protein autoubiquitination
0.43	GO:0010822	positive regulation of mitochondrion organization
0.42	GO:0070585	protein localization to mitochondrion
0.42	GO:0051094	positive regulation of developmental process

0.63	GO:0008270	zinc ion binding
0.50	GO:0016874	ligase activity
0.45	GO:0004842	ubiquitin-protein transferase activity
0.41	GO:0051020	GTPase binding

0.47	GO:0005741	mitochondrial outer membrane
0.45	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.50	EC:6	GO:0016874
0.45	KEGG:R03876	GO:0004842

tr|M9PDQ9|M9PDQ9_DROME
Uncharacterized protein, isoform D
Search

0.50	Calcium and calcium/calmodulin-dependent serine/threonine-protein kinase

0.40	GO:0016310	phosphorylation
0.35	GO:0032509	endosome transport via multivesicular body sorting pathway

0.51	GO:0016740	transferase activity
0.35	GO:0032266	phosphatidylinositol-3-phosphate binding
0.35	GO:0043130	ubiquitin binding

0.35

GO:0000814

ESCRT II complex

0.51

GO:0016740

tr|M9PDR0|M9PDR0_DROME
Thioester-containing protein 4, isoform C
Search

0.97	Thiolester containing protein IV

0.76	GO:0010951	negative regulation of endopeptidase activity
0.53	GO:0009620	response to fungus
0.43	GO:0032504	multicellular organism reproduction
0.41	GO:0050829	defense response to Gram-negative bacterium

0.76

GO:0004866

endopeptidase inhibitor activity

0.73	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

tr|M9PDR6|M9PDR6_DROME
Uncharacterized protein, isoform B
Search

0.41	GO:0097659	nucleic acid-templated transcription
0.40	GO:1903506	regulation of nucleic acid-templated transcription
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression
0.39	GO:0010467	gene expression
0.39	GO:0034645	cellular macromolecule biosynthetic process
0.38	GO:0016310	phosphorylation

0.54	GO:0003677	DNA binding
0.39	GO:0016301	kinase activity

0.42

GO:0005634

nucleus

tr|M9PDT0|M9PDT0_DROME
Uncharacterized protein, isoform C
Search

tr|M9PDT9|M9PDT9_DROME
Myosuppressin receptor 2, isoform C
Search

0.40	G-protein coupled receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.66	GO:0008344	adult locomotory behavior
0.61	GO:0008345	larval locomotory behavior
0.60	GO:0002209	behavioral defense response
0.32	GO:0035556	intracellular signal transduction

0.78

GO:0008528

G-protein coupled peptide receptor activity

0.54	GO:0005887	integral component of plasma membrane
0.31	GO:0005622	intracellular

tr|M9PDV2|M9PDV2_DROME
Tetraspanin
Search

0.58	Tetraspanin

0.37	GO:0007166	cell surface receptor signaling pathway
0.34	GO:0035188	hatching
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.33	GO:0016477	cell migration
0.33	GO:0045747	positive regulation of Notch signaling pathway
0.33	GO:0030707	ovarian follicle cell development
0.33	GO:0090132	epithelium migration
0.33	GO:0042098	T cell proliferation

0.35	GO:0043565	sequence-specific DNA binding
0.35	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005178	integrin binding

0.37	GO:0005887	integral component of plasma membrane
0.35	GO:0005634	nucleus
0.32	GO:0005604	basement membrane

tr|M9PDW8|M9PDW8_DROME
Uncharacterized protein, isoform T
Search

0.84	GO:0007498	mesoderm development
0.34	GO:1903474	anchoring of the mitotic actomyosin contractile ring to the plasma membrane

0.74

GO:0003779

actin binding

0.30	GO:0016020	membrane
0.30	GO:0005623	cell

tr|M9PDX2|M9PDX2_DROME
CG4577, isoform B
Search

0.53	GO:0007350	blastoderm segmentation
0.52	GO:0044324	regulation of transcription involved in anterior/posterior axis specification
0.51	GO:0000578	embryonic axis specification
0.51	GO:0032793	positive regulation of CREB transcription factor activity
0.51	GO:0007400	neuroblast fate determination
0.51	GO:0008293	torso signaling pathway
0.49	GO:0045944	positive regulation of transcription by RNA polymerase II
0.48	GO:0051289	protein homotetramerization
0.48	GO:0000122	negative regulation of transcription by RNA polymerase II
0.46	GO:0042594	response to starvation

0.49	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.49	GO:0008140	cAMP response element binding protein binding
0.49	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.42	GO:0046983	protein dimerization activity
0.42	GO:0003723	RNA binding
0.40	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding
0.40	GO:0050825	ice binding
0.40	GO:0003777	microtubule motor activity
0.40	GO:0008017	microtubule binding
0.39	GO:0045182	translation regulator activity

0.48	GO:0005634	nucleus
0.40	GO:0000785	chromatin
0.38	GO:0005737	cytoplasm
0.38	GO:0044815	DNA packaging complex
0.37	GO:0032993	protein-DNA complex
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.39

EC:2.4.1.198

GO:0017176

tr|M9PDX8|M9PDX8_DROME
Nervana 3, isoform E
Search

0.88	sodium/potassium-transporting ATPase subunit beta-2

0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.46	GO:0007605	sensory perception of sound
0.45	GO:0010996	response to auditory stimulus
0.42	GO:0035158	regulation of tube diameter, open tracheal system
0.42	GO:0060857	establishment of glial blood-brain barrier
0.42	GO:0061343	cell adhesion involved in heart morphogenesis
0.42	GO:0019991	septate junction assembly
0.41	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.39	GO:0090662	ATP hydrolysis coupled transmembrane transport

0.41	GO:0005391	sodium:potassium-exchanging ATPase activity
0.34	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.33	GO:0005509	calcium ion binding

0.85	GO:0005890	sodium:potassium-exchanging ATPase complex
0.41	GO:0005918	septate junction
0.40	GO:0030424	axon

0.41	EC:3.6.3.9	GO:0005391
0.34	KEGG:R05982 KEGG:R06722	GO:0004571

tr|M9PDY1|M9PDY1_DROME
Uncharacterized protein, isoform C
Search

0.30

GO:0044425

membrane part

tr|M9PDZ8|M9PDZ8_DROME
Ubr3 ubiquitin ligase, isoform B
Search

0.63	Zinc finger protein 650

0.58	GO:0034126	positive regulation of MyD88-dependent toll-like receptor signaling pathway
0.55	GO:0045880	positive regulation of smoothened signaling pathway
0.55	GO:0070936	protein K48-linked ubiquitination
0.54	GO:0051865	protein autoubiquitination
0.51	GO:0043066	negative regulation of apoptotic process
0.45	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway
0.36	GO:0007015	actin filament organization

0.60	GO:0008270	zinc ion binding
0.52	GO:0016874	ligase activity
0.51	GO:0061630	ubiquitin protein ligase activity
0.37	GO:0030674	protein binding, bridging
0.37	GO:0051015	actin filament binding
0.33	GO:0016829	lyase activity

0.47	GO:0005829	cytosol
0.41	GO:0000151	ubiquitin ligase complex
0.37	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.52

GO:0016874

tr|M9PE01|M9PE01_DROME
Ecdysone-induced protein 63E, isoform N
Search

0.36	Cell division protein kinase

0.63	GO:0006468	protein phosphorylation
0.53	GO:0002168	instar larval development
0.52	GO:0001700	embryonic development via the syncytial blastoderm
0.51	GO:0007552	metamorphosis
0.50	GO:0051726	regulation of cell cycle
0.49	GO:0048589	developmental growth
0.49	GO:0002009	morphogenesis of an epithelium
0.44	GO:0000086	G2/M transition of mitotic cell cycle
0.43	GO:0060828	regulation of canonical Wnt signaling pathway
0.39	GO:0051301	cell division

0.64	GO:0004672	protein kinase activity
0.56	GO:0020037	heme binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0030332	cyclin binding
0.46	GO:0060089	molecular transducer activity

0.46	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex
0.44	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane
0.39	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|M9PE19|M9PE19_DROME
Uncharacterized protein, isoform H
Search

0.42	Purine nucleoside phosphorylase

0.66	GO:0009116	nucleoside metabolic process
0.32	GO:0022904	respiratory electron transport chain

0.78	GO:0004731	purine-nucleoside phosphorylase activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0009055	electron transfer activity
0.32	GO:0032553	ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

0.78

EC:2.4.2.1

GO:0004731

tr|M9PE32|M9PE32_DROME
Fife, isoform D
Search

0.69	regulating synaptic membrane exocytosis protein 1

0.87	GO:2000809	positive regulation of synaptic vesicle clustering
0.86	GO:0001956	positive regulation of neurotransmitter secretion
0.86	GO:1904071	presynaptic active zone assembly
0.86	GO:0097091	synaptic vesicle clustering
0.32	GO:0016310	phosphorylation
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.32	GO:0043565	sequence-specific DNA binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0016301	kinase activity

0.85	GO:0048788	cytoskeleton of presynaptic active zone
0.30	GO:0016021	integral component of membrane

tr|M9PE35|M9PE35_DROME
RabX6, isoform B
Search

0.42	Rablike [Tribolium castaneum]

0.40	GO:0034389	lipid particle organization
0.39	GO:0032482	Rab protein signal transduction
0.36	GO:0016192	vesicle-mediated transport
0.34	GO:0000012	single strand break repair

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004767	sphingomyelin phosphodiesterase activity
0.33	GO:0003684	damaged DNA binding

0.47	GO:0043025	neuronal cell body
0.37	GO:0005794	Golgi apparatus
0.36	GO:0031982	vesicle
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.35	EC:3.1.4.12	GO:0004767
0.35	KEGG:R02541	GO:0004767

tr|M9PE53|M9PE53_DROME
Multiple wing hairs, isoform C
Search

MWH

0.81	Multiple wing hairs, isoform C

0.72	GO:0030036	actin cytoskeleton organization
0.70	GO:0035320	imaginal disc-derived wing hair site selection
0.62	GO:0030837	negative regulation of actin filament polymerization

0.76	GO:0017048	Rho GTPase binding
0.74	GO:0003779	actin binding
0.31	GO:0003677	DNA binding

0.37	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|M9PE54|M9PE54_DROME
CG3597, isoform B
Search

DHDH

0.63	Dimeric dihydrodiol dehydrogenase

0.52	GO:0055114	oxidation-reduction process
0.41	GO:0042843	D-xylose catabolic process
0.33	GO:0042981	regulation of apoptotic process
0.32	GO:0009058	biosynthetic process

0.54	GO:0016491	oxidoreductase activity
0.33	GO:0016779	nucleotidyltransferase activity
0.32	GO:0003723	RNA binding

0.30

GO:0031224

intrinsic component of membrane

0.54

GO:0016491

tr|M9PE65|M9PE65_DROME
Axotactin, isoform C
Search

0.60	Contactin-associated protein 2

0.72	GO:0010951	negative regulation of endopeptidase activity
0.54	GO:0019226	transmission of nerve impulse
0.34	GO:0000413	protein peptidyl-prolyl isomerization

0.74	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0005509	calcium ion binding
0.34	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.40	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.34

EC:5.2.1.8

GO:0003755

tr|M9PE71|M9PE71_DROME
Neuronal synaptobrevin, isoform J
Search

0.58	Vesicle-associated membrane protein 2

0.69	GO:0016192	vesicle-mediated transport
0.51	GO:0090174	organelle membrane fusion
0.50	GO:0016050	vesicle organization
0.41	GO:0097480	establishment of synaptic vesicle localization
0.41	GO:0099504	synaptic vesicle cycle
0.41	GO:0099643	signal release from synapse
0.41	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.40	GO:0140056	organelle localization by membrane tethering
0.40	GO:0006836	neurotransmitter transport
0.39	GO:0001505	regulation of neurotransmitter levels

0.51	GO:0000149	SNARE binding
0.50	GO:0005484	SNAP receptor activity
0.35	GO:0018024	histone-lysine N-methyltransferase activity
0.32	GO:0003735	structural constituent of ribosome

0.51	GO:0043195	terminal bouton
0.51	GO:0031201	SNARE complex
0.50	GO:0048786	presynaptic active zone
0.50	GO:0008021	synaptic vesicle
0.40	GO:0005886	plasma membrane
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.35

GO:0018024

tr|M9PE88|M9PE88_DROME
Receptor protein serine/threonine kinase
Search

0.52	Receptor protein serine/threonine kinase

0.79	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.66	GO:0023014	signal transduction by protein phosphorylation
0.61	GO:0051094	positive regulation of developmental process
0.60	GO:0051240	positive regulation of multicellular organismal process
0.59	GO:2000026	regulation of multicellular organismal development
0.58	GO:0045927	positive regulation of growth
0.58	GO:1904398	positive regulation of neuromuscular junction development
0.57	GO:0048638	regulation of developmental growth
0.57	GO:0048731	system development
0.56	GO:0007274	neuromuscular synaptic transmission

0.79	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.78	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0036122	BMP binding
0.42	GO:0046872	metal ion binding
0.35	GO:0004334	fumarylacetoacetase activity
0.35	GO:0016831	carboxy-lyase activity

0.57	GO:0098820	trans-synaptic protein complex
0.55	GO:0045202	synapse
0.55	GO:0055037	recycling endosome
0.53	GO:0005769	early endosome
0.45	GO:0005901	caveola
0.45	GO:0005913	cell-cell adherens junction
0.43	GO:0009986	cell surface
0.43	GO:0097458	neuron part
0.41	GO:0005654	nucleoplasm
0.40	GO:0005887	integral component of plasma membrane

0.79	EC:2.7.11	GO:0004675
0.35	KEGG:R01364	GO:0004334

tr|M9PEA2|M9PEA2_DROME
CDK2-associated protein 1, isoform B
Search

0.66	Cyclin-dependent kinase 2-associated protein 1

0.55	GO:0016310	phosphorylation
0.50	GO:0001934	positive regulation of protein phosphorylation

0.57	GO:0016301	kinase activity
0.55	GO:0070182	DNA polymerase binding

0.44	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|M9PEA4|M9PEA4_DROME
Uncharacterized protein, isoform B
Search

0.84	GO:0038202	TORC1 signaling
0.72	GO:0009967	positive regulation of signal transduction
0.36	GO:0055085	transmembrane transport

0.81

GO:0005070

SH3/SH2 adaptor activity

0.44	GO:0005622	intracellular
0.30	GO:0044425	membrane part

tr|M9PEC0|M9PEC0_DROME
Myosuppressin receptor 1, isoform B
Search

0.40	G-protein coupled receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.67	GO:0008344	adult locomotory behavior
0.55	GO:0008345	larval locomotory behavior
0.55	GO:0002209	behavioral defense response
0.33	GO:0035556	intracellular signal transduction

0.78

GO:0008528

G-protein coupled peptide receptor activity

0.55	GO:0005887	integral component of plasma membrane
0.32	GO:0005622	intracellular

tr|M9PED9|M9PED9_DROME
Uncharacterized protein, isoform C
Search

101893659

0.36	Leucine Rich repeat protein

0.58	GO:0043085	positive regulation of catalytic activity
0.54	GO:0006508	proteolysis

0.66	GO:0019211	phosphatase activator activity
0.61	GO:0004222	metalloendopeptidase activity
0.60	GO:0016758	transferase activity, transferring hexosyl groups
0.55	GO:0008270	zinc ion binding

0.64	GO:0031012	extracellular matrix
0.62	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.61

EC:3.4.24

GO:0004222

tr|M9PEE4|M9PEE4_DROME
Uncharacterized protein, isoform A
Search

0.81	GO:0090175	regulation of establishment of planar polarity
0.37	GO:0009967	positive regulation of signal transduction
0.34	GO:0007165	signal transduction
0.32	GO:0055085	transmembrane transport

0.43	GO:0046872	metal ion binding
0.38	GO:0005070	SH3/SH2 adaptor activity
0.33	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.30

GO:0044425

membrane part

tr|M9PEE6|M9PEE6_DROME
Tetraspanin 66A, isoform E
Search

TSP66A

0.92	Tetraspanin 66A, isoform E

0.30

GO:0044425

membrane part

tr|M9PEG1|M9PEG1_DROME
Uncharacterized protein
Search

0.34	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

0.57

GO:0016310

phosphorylation

0.60

GO:0016301

kinase activity

tr|M9PEG2|M9PEG2_DROME
Uncharacterized protein, isoform C
Search

0.35

GO:0006508

proteolysis

0.36	GO:0008237	metallopeptidase activity
0.34	GO:0004175	endopeptidase activity

0.30

GO:0031224

intrinsic component of membrane

tr|M9PEG6|M9PEG6_DROME
Zinc transporter 63C, isoform F
Search

0.53	Cation efflux protein/ zinc transporter

0.61	GO:0098655	cation transmembrane transport
0.52	GO:0010312	detoxification of zinc ion
0.50	GO:0006882	cellular zinc ion homeostasis
0.49	GO:0006829	zinc II ion transport
0.42	GO:0098660	inorganic ion transmembrane transport
0.41	GO:0061088	regulation of sequestering of zinc ion
0.33	GO:0010469	regulation of receptor activity
0.33	GO:0006310	DNA recombination
0.32	GO:0055114	oxidation-reduction process

0.61	GO:0008324	cation transmembrane transporter activity
0.45	GO:0015562	efflux transmembrane transporter activity
0.42	GO:0015318	inorganic molecular entity transmembrane transporter activity
0.34	GO:0070035	purine NTP-dependent helicase activity
0.34	GO:0008083	growth factor activity
0.33	GO:0042623	ATPase activity, coupled
0.33	GO:0008270	zinc ion binding
0.33	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.49	GO:0016323	basolateral plasma membrane
0.48	GO:0016324	apical plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

GO:0032440

tr|M9PEH8|M9PEH8_DROME
Uncharacterized protein, isoform D
Search

PP6R2

0.68	serine/threonine-protein phosphatase 6 regulatory subunit 3

0.85	GO:0046329	negative regulation of JNK cascade
0.36	GO:0031591	wybutosine biosynthetic process
0.32	GO:0055114	oxidation-reduction process

0.35	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
0.34	GO:0000049	tRNA binding

0.30

GO:0016020

membrane

0.35

EC:1.14.11

GO:0016706

tr|M9PEI0|M9PEI0_DROME
Uncharacterized protein, isoform D
Search

0.77

GO:0006030

chitin metabolic process

0.76	GO:0008061	chitin binding
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.32	GO:0003723	RNA binding

0.66	GO:0005576	extracellular region
0.36	GO:0005581	collagen trimer
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016747

tr|M9PEI6|M9PEI6_DROME
Dikar, isoform F
Search

DIKAR

0.95	Dikar, isoform F

0.81	GO:0007616	long-term memory
0.46	GO:0043044	ATP-dependent chromatin remodeling
0.37	GO:0045454	cell redox homeostasis
0.35	GO:0006886	intracellular protein transport
0.34	GO:0021915	neural tube development
0.32	GO:0009058	biosynthetic process
0.32	GO:0032259	methylation

0.37	GO:0140034	methylation-dependent protein binding
0.37	GO:0042393	histone binding
0.34	GO:0030170	pyridoxal phosphate binding
0.34	GO:0016853	isomerase activity
0.33	GO:0016740	transferase activity
0.32	GO:0003723	RNA binding
0.31	GO:0046872	metal ion binding

0.50	GO:0090537	CERF complex
0.37	GO:0016589	NURF complex
0.35	GO:0005581	collagen trimer
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016853

tr|M9PEJ0|M9PEJ0_DROME
CG7120, isoform F
Search

0.46	Lipoteichoic acid synthase 2

0.38	GO:0032504	multicellular organism reproduction
0.30	GO:0008152	metabolic process

0.33	GO:0005509	calcium ion binding
0.30	GO:0003824	catalytic activity

0.37	GO:0005615	extracellular space
0.30	GO:0044425	membrane part

tr|M9PEJ6|M9PEJ6_DROME
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|M9PEK4|M9PEK4_DROME
Uncharacterized protein
Search

tr|M9PEM1|M9PEM1_DROME
Syntaxin 17, isoform B
Search

STX17

0.65	Syntaxin 17, isoform B

0.86	GO:0097111	endoplasmic reticulum-Golgi intermediate compartment organization
0.85	GO:0097352	autophagosome maturation
0.78	GO:0006888	ER to Golgi vesicle-mediated transport
0.68	GO:0070050	neuron cellular homeostasis
0.61	GO:0009267	cellular response to starvation
0.58	GO:0010506	regulation of autophagy
0.55	GO:0061025	membrane fusion
0.46	GO:0016081	synaptic vesicle docking
0.41	GO:0048284	organelle fusion
0.41	GO:0016050	vesicle organization

0.82	GO:0000149	SNARE binding
0.63	GO:0005484	SNAP receptor activity
0.59	GO:0032403	protein complex binding
0.36	GO:0005509	calcium ion binding

0.67	GO:0000421	autophagosome membrane
0.64	GO:0031201	SNARE complex
0.43	GO:0098793	presynapse
0.38	GO:0012505	endomembrane system
0.37	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|M9PEM2|M9PEM2_DROME
Uncharacterized protein, isoform E
Search

LOC108089841

0.58	UHRF1-binding protein 1 isoform X3

0.47	GO:0035725	sodium ion transmembrane transport
0.38	GO:0000395	mRNA 5'-splice site recognition
0.38	GO:0000387	spliceosomal snRNP assembly

0.48	GO:0005272	sodium channel activity
0.44	GO:0042826	histone deacetylase binding
0.41	GO:0042802	identical protein binding
0.38	GO:0030619	U1 snRNA binding
0.37	GO:0003729	mRNA binding
0.37	GO:0004386	helicase activity
0.36	GO:0008270	zinc ion binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0000243	commitment complex
0.38	GO:0071004	U2-type prespliceosome
0.38	GO:0005685	U1 snRNP
0.30	GO:0016020	membrane

tr|M9PEN8|M9PEN8_DROME
Rh50, isoform B
Search

0.38	Ammonium transporter Rh type B-A

0.77	GO:0072488	ammonium transmembrane transport
0.42	GO:0019755	one-carbon compound transport
0.41	GO:0015695	organic cation transport
0.38	GO:0060586	multicellular organismal iron ion homeostasis
0.38	GO:0048821	erythrocyte development
0.36	GO:0015669	gas transport
0.36	GO:0006873	cellular ion homeostasis
0.36	GO:0042886	amide transport
0.36	GO:0097272	ammonia homeostasis
0.35	GO:0015893	drug transport

0.77	GO:0008519	ammonium transmembrane transporter activity
0.39	GO:0022842	narrow pore channel activity
0.38	GO:0030506	ankyrin binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.39

GO:0005887

integral component of plasma membrane

tr|M9PEP2|M9PEP2_DROME
Adenylyl cyclase 35C, isoform C
Search

AC13E

0.63	adenylate cyclase type 9

0.75	GO:0009190	cyclic nucleotide biosynthetic process
0.62	GO:0035556	intracellular signal transduction
0.59	GO:0046058	cAMP metabolic process
0.52	GO:0009152	purine ribonucleotide biosynthetic process
0.42	GO:0046068	cGMP metabolic process
0.35	GO:0006281	DNA repair
0.33	GO:0043547	positive regulation of GTPase activity
0.33	GO:0008610	lipid biosynthetic process
0.32	GO:0055114	oxidation-reduction process

0.74	GO:0016849	phosphorus-oxygen lyase activity
0.59	GO:0009975	cyclase activity
0.52	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.34	GO:0003677	DNA binding
0.33	GO:0005096	GTPase activator activity
0.33	GO:0005506	iron ion binding
0.32	GO:0016491	oxidoreductase activity

0.45	GO:0005622	intracellular
0.37	GO:0043234	protein complex
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.74

EC:4.6

GO:0016849

tr|M9PEP7|M9PEP7_DROME
Uncharacterized protein
Search

0.78	GO:0006030	chitin metabolic process
0.41	GO:0055085	transmembrane transport

0.77	GO:0008061	chitin binding
0.45	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.41	GO:0030554	adenyl nucleotide binding
0.40	GO:0032555	purine ribonucleotide binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|M9PEP9|M9PEP9_DROME
Uncharacterized protein, isoform I
Search

0.36

GO:0016310

phosphorylation

0.37

GO:0016301

kinase activity

0.30

GO:0044425

membrane part

tr|M9PEQ7|M9PEQ7_DROME
Uncharacterized protein, isoform B
Search

0.46	PR domain zinc finger protein 8

0.46	GO:0014003	oligodendrocyte development
0.38	GO:0045892	negative regulation of transcription, DNA-templated
0.36	GO:0021540	corpus callosum morphogenesis
0.36	GO:0021957	corticospinal tract morphogenesis
0.36	GO:0051567	histone H3-K9 methylation
0.33	GO:0007166	cell surface receptor signaling pathway
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:0006414	translational elongation

0.51	GO:0003676	nucleic acid binding
0.40	GO:0003714	transcription corepressor activity
0.39	GO:0003682	chromatin binding
0.36	GO:0046974	histone methyltransferase activity (H3-K9 specific)
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.39	GO:0005634	nucleus
0.33	GO:0034708	methyltransferase complex
0.32	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|M9PER1|M9PER1_DROME
Autophagy-related 18a, isoform E
Search

LOC108089017

0.73	WD repeat domain phosphoinositide-interacting protein 2

0.83	GO:0000045	autophagosome assembly
0.50	GO:0061723	glycophagy
0.50	GO:0035096	larval midgut cell programmed cell death
0.50	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling
0.48	GO:0050688	regulation of defense response to virus
0.46	GO:0009267	cellular response to starvation
0.46	GO:0051607	defense response to virus
0.45	GO:0010506	regulation of autophagy
0.38	GO:0006497	protein lipidation
0.38	GO:0044804	autophagy of nucleus

0.85	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.83	GO:0032266	phosphatidylinositol-3-phosphate binding

0.83	GO:0000407	phagophore assembly site
0.47	GO:0005776	autophagosome
0.37	GO:0098805	whole membrane
0.37	GO:0005829	cytosol
0.36	GO:0019898	extrinsic component of membrane
0.35	GO:0005654	nucleoplasm
0.34	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

tr|M9PER3|M9PER3_DROME
Uncharacterized protein, isoform D
Search

0.72	GO:1903507	negative regulation of nucleic acid-templated transcription
0.58	GO:0006351	transcription, DNA-templated
0.38	GO:0035024	negative regulation of Rho protein signal transduction
0.35	GO:0030336	negative regulation of cell migration
0.33	GO:0006355	regulation of transcription, DNA-templated

0.81	GO:0003714	transcription corepressor activity
0.31	GO:0005515	protein binding

0.37	GO:0005634	nucleus
0.34	GO:0012505	endomembrane system
0.33	GO:0031967	organelle envelope
0.33	GO:0031090	organelle membrane
0.33	GO:0005737	cytoplasm
0.31	GO:0031974	membrane-enclosed lumen
0.30	GO:0016021	integral component of membrane

tr|M9PET2|M9PET2_DROME
Target of wingless, isoform E
Search

TOW

0.97	Target of wingless, isoform E

0.83	GO:0035317	imaginal disc-derived wing hair organization
0.82	GO:0045879	negative regulation of smoothened signaling pathway
0.80	GO:0001736	establishment of planar polarity
0.37	GO:0032922	circadian regulation of gene expression
0.37	GO:0009648	photoperiodism
0.36	GO:0045893	positive regulation of transcription, DNA-templated
0.36	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0009266	response to temperature stimulus
0.35	GO:0043412	macromolecule modification
0.35	GO:0007366	periodic partitioning by pair rule gene

0.37	GO:0005515	protein binding
0.36	GO:0004674	protein serine/threonine kinase activity
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0140110	transcription regulator activity
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0003677	DNA binding
0.34	GO:0005545	1-phosphatidylinositol binding
0.34	GO:0005452	inorganic anion exchanger activity

0.59	GO:0005634	nucleus
0.35	GO:0005667	transcription factor complex
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:0000785	chromatin
0.34	GO:0030136	clathrin-coated vesicle
0.33	GO:0012505	endomembrane system
0.33	GO:0031967	organelle envelope
0.30	GO:0016020	membrane

0.36

GO:0004674

tr|M9PET5|M9PET5_DROME
CG6282, isoform D
Search

0.15	Oxidoreductase

0.61	GO:0006629	lipid metabolic process
0.51	GO:0055114	oxidation-reduction process
0.33	GO:0035556	intracellular signal transduction
0.33	GO:1901575	organic substance catabolic process

0.66	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.34	GO:0004435	phosphatidylinositol phospholipase C activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0016846	carbon-sulfur lyase activity
0.33	GO:0004871	signal transducer activity

0.48	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.66	EC:1.3	GO:0016627
0.34	KEGG:R03435	GO:0004435

tr|M9PEU1|M9PEU1_DROME
Uncharacterized protein, isoform G
Search

0.49	Proton-coupled amino acid transporter 4

0.36	GO:0003333	amino acid transmembrane transport
0.33	GO:0016311	dephosphorylation

0.36	GO:0015171	amino acid transmembrane transporter activity
0.33	GO:0003993	acid phosphatase activity
0.32	GO:0046872	metal ion binding

0.36	GO:0005774	vacuolar membrane
0.30	GO:0016021	integral component of membrane

0.33

EC:3.1.3.2

GO:0003993

tr|M9PEV1|M9PEV1_DROME
CG8564, isoform C
Search

0.37	zinc carboxypeptidase

0.61	GO:0006508	proteolysis
0.34	GO:0006486	protein glycosylation
0.34	GO:0071555	cell wall organization
0.33	GO:0000272	polysaccharide catabolic process

0.78	GO:0004181	metallocarboxypeptidase activity
0.63	GO:0008270	zinc ion binding
0.34	GO:0008378	galactosyltransferase activity
0.33	GO:0030246	carbohydrate binding

0.39	GO:0005615	extracellular space
0.34	GO:0005773	vacuole
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:3.4.17

GO:0004181

tr|M9PEW1|M9PEW1_DROME
Uncharacterized protein, isoform E
Search

0.34	Acyl-protein thioesterase

0.48	GO:0002084	protein depalmitoylation
0.35	GO:0006631	fatty acid metabolic process
0.34	GO:0007411	axon guidance
0.33	GO:0006357	regulation of transcription by RNA polymerase II
0.33	GO:0006414	translational elongation

0.51	GO:0016787	hydrolase activity
0.45	GO:0045296	cadherin binding
0.39	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0003746	translation elongation factor activity
0.32	GO:0003735	structural constituent of ribosome

0.44	GO:0005795	Golgi stack
0.35	GO:0070062	extracellular exosome
0.33	GO:0070449	elongin complex
0.33	GO:0005829	cytosol
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.51

GO:0016787

tr|M9PEY2|M9PEY2_DROME
Uncharacterized protein
Search

tr|M9PEY3|M9PEY3_DROME
Uncharacterized protein
Search

tr|M9PEZ6|M9PEZ6_DROME
Uncharacterized protein, isoform F
Search

0.32

GO:0055085

transmembrane transport

0.33

GO:0016874

ligase activity

0.30

GO:0044425

membrane part

0.33

GO:0016874

tr|M9PF00|M9PF00_DROME
Corazonin receptor, isoform B
Search

CRZR

0.65	gonadotropin-releasing hormone receptor

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.66	GO:0006117	acetaldehyde metabolic process
0.63	GO:0071361	cellular response to ethanol
0.62	GO:0048149	behavioral response to ethanol
0.34	GO:0097211	cellular response to gonadotropin-releasing hormone
0.33	GO:0007602	phototransduction
0.33	GO:0007601	visual perception
0.33	GO:0018298	protein-chromophore linkage
0.33	GO:0046887	positive regulation of hormone secretion
0.33	GO:0071482	cellular response to light stimulus

0.71	GO:0004930	G-protein coupled receptor activity
0.58	GO:0001653	peptide receptor activity
0.37	GO:0016500	protein-hormone receptor activity
0.33	GO:0009881	photoreceptor activity
0.33	GO:0042277	peptide binding

0.51	GO:0005887	integral component of plasma membrane
0.33	GO:0043204	perikaryon
0.33	GO:0030424	axon
0.32	GO:0005654	nucleoplasm

tr|M9PF07|M9PF07_DROME
Uncharacterized protein, isoform A
Search

tr|M9PF20|M9PF20_DROME
Trailer hitch, isoform H
Search

TRAL

0.66	Trailer hitch, isoform H

0.76	GO:0000226	microtubule cytoskeleton organization
0.73	GO:0030036	actin cytoskeleton organization
0.34	GO:0006468	protein phosphorylation
0.34	GO:0035556	intracellular signal transduction

0.53	GO:0005515	protein binding
0.35	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046872	metal ion binding

0.86	GO:0045169	fusome
0.85	GO:0043186	P granule
0.70	GO:0005783	endoplasmic reticulum
0.57	GO:0005829	cytosol

0.35

GO:0004674

tr|M9PF47|M9PF47_DROME
Forkhead box K, isoform N
Search

0.75	Fork head transcription factor long isoform

0.69	GO:0007495	visceral mesoderm-endoderm interaction involved in midgut development
0.62	GO:0098586	cellular response to virus
0.58	GO:0051607	defense response to virus
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0010604	positive regulation of macromolecule metabolic process
0.40	GO:0030154	cell differentiation
0.40	GO:0009653	anatomical structure morphogenesis
0.38	GO:0045935	positive regulation of nucleobase-containing compound metabolic process

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.39	GO:0001012	RNA polymerase II regulatory region DNA binding
0.38	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.34	GO:0044599	AP-5 adaptor complex
0.30	GO:0016021	integral component of membrane

tr|M9PF56|M9PF56_DROME
Dyschronic, isoform G
Search

LOC108086918

0.97	membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 isoform X6

0.81	GO:0007605	sensory perception of sound
0.78	GO:0050953	sensory perception of light stimulus
0.51	GO:1900074	negative regulation of neuromuscular synaptic transmission
0.50	GO:0072499	photoreceptor cell axon guidance
0.50	GO:0042052	rhabdomere development
0.49	GO:0045475	locomotor rhythm
0.49	GO:0046716	muscle cell cellular homeostasis
0.49	GO:0008582	regulation of synaptic growth at neuromuscular junction
0.48	GO:0032414	positive regulation of ion transmembrane transporter activity
0.35	GO:0016310	phosphorylation

0.36	GO:0016301	kinase activity
0.33	GO:0004252	serine-type endopeptidase activity
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0045202	synapse
0.30	GO:0031224	intrinsic component of membrane
0.30	GO:0005623	cell

0.33

GO:0004252

tr|M9PF57|M9PF57_DROME
Uncharacterized protein, isoform M
Search

0.82	GO:0007498	mesoderm development
0.33	GO:0006508	proteolysis
0.33	GO:0006886	intracellular protein transport
0.33	GO:0006888	ER to Golgi vesicle-mediated transport
0.33	GO:0031047	gene silencing by RNA
0.32	GO:0006413	translational initiation
0.32	GO:0032774	RNA biosynthetic process

0.35	GO:0005544	calcium-dependent phospholipid binding
0.35	GO:0005509	calcium ion binding
0.34	GO:0016853	isomerase activity
0.34	GO:0008237	metallopeptidase activity
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0003743	translation initiation factor activity
0.32	GO:0008270	zinc ion binding

0.33	GO:0030127	COPII vesicle coat
0.30	GO:0016021	integral component of membrane

0.34

GO:0016853

tr|M9PF59|M9PF59_DROME
Uncharacterized protein, isoform B
Search

0.12

hornerin

0.80	GO:0007480	imaginal disc-derived leg morphogenesis
0.71	GO:0035023	regulation of Rho protein signal transduction
0.61	GO:0065009	regulation of molecular function
0.57	GO:0046579	positive regulation of Ras protein signal transduction
0.41	GO:0071897	DNA biosynthetic process
0.41	GO:0006260	DNA replication

0.71	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.49	GO:0050825	ice binding
0.42	GO:0003887	DNA-directed DNA polymerase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0003677	DNA binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0009360	DNA polymerase III complex
0.30	GO:0016020	membrane

0.42

GO:0003887

tr|M9PF61|M9PF61_DROME
CG6084, isoform C
Search

0.38	Aldo-keto reductase

0.53	GO:0055114	oxidation-reduction process
0.36	GO:0001523	retinoid metabolic process
0.35	GO:0016488	farnesol catabolic process
0.35	GO:0044598	doxorubicin metabolic process
0.35	GO:0044597	daunorubicin metabolic process
0.34	GO:0006081	cellular aldehyde metabolic process
0.34	GO:0007586	digestion
0.34	GO:0008202	steroid metabolic process

0.54	GO:0016491	oxidoreductase activity
0.34	GO:0005536	glucose binding
0.34	GO:0070401	NADP+ binding
0.34	GO:0070402	NADPH binding
0.33	GO:0005515	protein binding

0.34	GO:0005829	cytosol
0.34	GO:0070062	extracellular exosome
0.34	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0012505	endomembrane system
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.54

GO:0016491

tr|M9PF64|M9PF64_DROME
Uncharacterized protein, isoform C
Search

0.11	52 kDa repressor of the inhibitor of the protein kinase

0.37

GO:0016310

phosphorylation

0.55	GO:0003677	DNA binding
0.38	GO:0016301	kinase activity

tr|M9PF67|M9PF67_DROME
Black match, isoform F
Search

BMA

0.96	Black match, isoform F

0.62

GO:0006468

protein phosphorylation

0.62	GO:0004672	protein kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|M9PF73|M9PF73_DROME
Uncharacterized protein, isoform C
Search

0.78

GO:0006030

chitin metabolic process

0.77

GO:0008061

chitin binding

0.66

GO:0005576

extracellular region

tr|M9PF78|M9PF78_DROME
Sarcoglycan alpha, isoform C
Search

0.84	Epsilon-sarcoglycan

0.39	GO:0003012	muscle system process
0.37	GO:0061024	membrane organization
0.35	GO:0006629	lipid metabolic process
0.33	GO:0055114	oxidation-reduction process

0.65	GO:0005509	calcium ion binding
0.46	GO:0008307	structural constituent of muscle
0.35	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors

0.85	GO:0016012	sarcoglycan complex
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:1.3

GO:0016627

tr|M9PF79|M9PF79_DROME
Simjang, isoform E
Search

SIMJ

0.97	Simjang, isoform E

0.83	GO:0060912	cardiac cell fate specification
0.80	GO:0046959	habituation
0.79	GO:0045887	positive regulation of synaptic growth at neuromuscular junction
0.69	GO:0000122	negative regulation of transcription by RNA polymerase II
0.42	GO:0045879	negative regulation of smoothened signaling pathway
0.38	GO:0042742	defense response to bacterium
0.34	GO:0043044	ATP-dependent chromatin remodeling
0.32	GO:0006351	transcription, DNA-templated

0.49	GO:0043565	sequence-specific DNA binding
0.49	GO:0008270	zinc ion binding
0.48	GO:0003700	DNA binding transcription factor activity
0.45	GO:0005515	protein binding
0.35	GO:0031492	nucleosomal DNA binding
0.35	GO:0035326	enhancer binding
0.34	GO:0001012	RNA polymerase II regulatory region DNA binding
0.34	GO:0003690	double-stranded DNA binding

0.76	GO:0090545	CHD-type complex
0.74	GO:0090568	nuclear transcriptional repressor complex
0.73	GO:0000118	histone deacetylase complex
0.36	GO:0005576	extracellular region
0.34	GO:0016607	nuclear speck
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

tr|M9PF81|M9PF81_DROME
CG7906, isoform B
Search

0.59

GO:0003723

RNA binding

tr|M9PF84|M9PF84_DROME
Klumpfuss, isoform B
Search

0.97

Klumpfuss

0.66	GO:0046672	positive regulation of compound eye retinal cell programmed cell death
0.65	GO:0030536	larval feeding behavior
0.65	GO:2000035	regulation of stem cell division
0.65	GO:0014019	neuroblast development
0.65	GO:0016360	sensory organ precursor cell fate determination
0.63	GO:0002052	positive regulation of neuroblast proliferation
0.63	GO:0097150	neuronal stem cell population maintenance
0.53	GO:0006099	tricarboxylic acid cycle
0.48	GO:0046580	negative regulation of Ras protein signal transduction
0.32	GO:0090501	RNA phosphodiester bond hydrolysis

0.57	GO:0035326	enhancer binding
0.47	GO:0043565	sequence-specific DNA binding
0.32	GO:0004540	ribonuclease activity
0.32	GO:0003723	RNA binding
0.31	GO:0004519	endonuclease activity
0.31	GO:0000287	magnesium ion binding
0.31	GO:0008270	zinc ion binding
0.31	GO:0003700	DNA binding transcription factor activity

0.48	GO:0005634	nucleus
0.32	GO:0009898	cytoplasmic side of plasma membrane
0.31	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|M9PF86|M9PF86_DROME
CG3919, isoform C
Search

0.12	transcription factor Adf-1

0.58	GO:0097659	nucleic acid-templated transcription
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0010467	gene expression
0.53	GO:0034645	cellular macromolecule biosynthetic process

0.55

GO:0003677

DNA binding

0.61

GO:0005634

nucleus

tr|M9PFA9|M9PFA9_DROME
Uncharacterized protein, isoform B
Search

0.10	zinc finger protein 93

0.46	GO:1903506	regulation of nucleic acid-templated transcription
0.46	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:0010468	regulation of gene expression
0.44	GO:0007284	spermatogonial cell division
0.41	GO:0006351	transcription, DNA-templated

0.52	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.45	GO:0003700	DNA binding transcription factor activity
0.32	GO:0005515	protein binding

0.54

GO:0005634

nucleus

tr|M9PFC1|M9PFC1_DROME
Uncharacterized protein, isoform B
Search

0.10	cell surface glycoprotein 1

0.61	GO:0006030	chitin metabolic process
0.44	GO:0006508	proteolysis
0.38	GO:0009057	macromolecule catabolic process
0.37	GO:1901136	carbohydrate derivative catabolic process
0.37	GO:0000270	peptidoglycan metabolic process
0.37	GO:0030243	cellulose metabolic process
0.36	GO:0051568	histone H3-K4 methylation
0.36	GO:1901565	organonitrogen compound catabolic process
0.36	GO:0044275	cellular carbohydrate catabolic process
0.36	GO:0006468	protein phosphorylation

0.61	GO:0008061	chitin binding
0.46	GO:0004252	serine-type endopeptidase activity
0.38	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
0.37	GO:0030246	carbohydrate binding
0.37	GO:0008270	zinc ion binding
0.37	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.36	GO:0016798	hydrolase activity, acting on glycosyl bonds
0.36	GO:0004672	protein kinase activity
0.35	GO:0001871	pattern binding
0.35	GO:0003993	acid phosphatase activity

0.55	GO:0005576	extracellular region
0.44	GO:0005618	cell wall
0.37	GO:0044666	MLL3/4 complex
0.36	GO:0012511	monolayer-surrounded lipid storage body
0.30	GO:0031224	intrinsic component of membrane

0.46

GO:0004252

tr|M9PFD1|M9PFD1_DROME
Uncharacterized protein
Search

tr|M9PFD5|M9PFD5_DROME
CG9760, isoform D
Search

0.37	Type II inositol 1,4,5-trisphosphate 5-phosphatase

0.35	GO:0018298	protein-chromophore linkage
0.34	GO:0007186	G-protein coupled receptor signaling pathway

0.35	GO:0009881	photoreceptor activity
0.34	GO:0004930	G-protein coupled receptor activity
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0044425

membrane part

tr|M9PFG1|M9PFG1_DROME
Lethal (3) 72Dn, isoform B
Search

0.49	U3 small nucleolar RNA-associated protein 4 homolog

0.44	GO:0030490	maturation of SSU-rRNA
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression

0.42	GO:0030246	carbohydrate binding
0.38	GO:0003677	DNA binding

0.47	GO:0034455	t-UTP complex
0.46	GO:0001650	fibrillar center
0.41	GO:0005694	chromosome
0.30	GO:0044425	membrane part

tr|M9PFG6|M9PFG6_DROME
Sox21a, isoform B
Search

0.10	transcription factor SOX-14

0.59	GO:1903703	enterocyte differentiation
0.54	GO:0072089	stem cell proliferation
0.52	GO:0045596	negative regulation of cell differentiation
0.42	GO:1903506	regulation of nucleic acid-templated transcription
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.42	GO:0010468	regulation of gene expression
0.35	GO:0048513	animal organ development
0.34	GO:0022405	hair cycle process
0.34	GO:0048863	stem cell differentiation
0.34	GO:0008544	epidermis development

0.55	GO:0003677	DNA binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0001067	regulatory region nucleic acid binding

0.61

GO:0005634

nucleus

0.34

GO:0032440

tr|M9PFH7|M9PFH7_DROME
Tartan, isoform B
Search

0.68	Leucine-rich repeat neuronal protein 3

0.61	GO:0007436	larval salivary gland morphogenesis
0.60	GO:0035147	branch fusion, open tracheal system
0.58	GO:0008045	motor neuron axon guidance
0.47	GO:0072499	photoreceptor cell axon guidance
0.45	GO:0007416	synapse assembly
0.45	GO:0007155	cell adhesion
0.43	GO:0016477	cell migration
0.33	GO:0006032	chitin catabolic process
0.32	GO:0016998	cell wall macromolecule catabolic process

0.33	GO:0005515	protein binding
0.33	GO:0004568	chitinase activity

0.48	GO:0035230	cytoneme
0.47	GO:0036194	muscle cell projection
0.30	GO:0016020	membrane

0.33

EC:3.2.1.14

GO:0004568

tr|M9PFI7|M9PFI7_DROME
Uncharacterized protein
Search

tr|M9PFK3|M9PFK3_DROME
Uncharacterized protein, isoform B
Search

0.11

atherin

0.44	GO:0018298	protein-chromophore linkage
0.44	GO:0007186	G-protein coupled receptor signaling pathway
0.42	GO:0006886	intracellular protein transport
0.41	GO:0007602	phototransduction
0.41	GO:0051260	protein homooligomerization
0.41	GO:0007601	visual perception
0.38	GO:0009966	regulation of signal transduction
0.37	GO:1903077	negative regulation of protein localization to plasma membrane
0.36	GO:0065009	regulation of molecular function
0.36	GO:0043066	negative regulation of apoptotic process

0.60	GO:0005544	calcium-dependent phospholipid binding
0.53	GO:0005509	calcium ion binding
0.45	GO:0009881	photoreceptor activity
0.44	GO:0004930	G-protein coupled receptor activity
0.38	GO:0016918	retinal binding
0.38	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.37	GO:0005123	death receptor binding
0.36	GO:0003713	transcription coactivator activity
0.34	GO:0003676	nucleic acid binding
0.34	GO:0032559	adenyl ribonucleotide binding

0.36	GO:0005765	lysosomal membrane
0.36	GO:0010008	endosome membrane
0.36	GO:0070603	SWI/SNF superfamily-type complex
0.35	GO:0005794	Golgi apparatus
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

GO:0016787

tr|M9PFK5|M9PFK5_DROME
CG7510, isoform B
Search

0.46	Integral membrane protein GPR155

0.59	GO:0035556	intracellular signal transduction
0.54	GO:0055085	transmembrane transport
0.37	GO:0006030	chitin metabolic process
0.33	GO:0007166	cell surface receptor signaling pathway

0.36	GO:0008061	chitin binding
0.33	GO:0099600	transmembrane receptor activity
0.33	GO:0038023	signaling receptor activity

0.43	GO:0005622	intracellular
0.35	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

tr|M9PFM8|M9PFM8_DROME
Uncharacterized protein, isoform D
Search

0.30

GO:0044425

membrane part

tr|M9PFN0|M9PFN0_DROME
CG5830, isoform B
Search

0.43	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase

0.68	GO:0016311	dephosphorylation
0.38	GO:0036211	protein modification process
0.37	GO:0044267	cellular protein metabolic process
0.34	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.34	GO:0006857	oligopeptide transport
0.33	GO:0001933	negative regulation of protein phosphorylation
0.32	GO:0055085	transmembrane transport

0.69	GO:0016791	phosphatase activity
0.37	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0044548	S100 protein binding
0.34	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0015631	tubulin binding
0.32	GO:0022857	transmembrane transporter activity
0.32	GO:0046872	metal ion binding

0.35	GO:0000139	Golgi membrane
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.69

EC:3.1.3 EC:3.1.3.41

GO:0016791

tr|M9PFN6|M9PFN6_DROME
Uncharacterized protein, isoform A
Search

tr|M9PFR2|M9PFR2_DROME
TMS1, isoform F
Search

0.51	Serine incorporator 1

0.58	GO:0006658	phosphatidylserine metabolic process
0.55	GO:0006665	sphingolipid metabolic process
0.49	GO:0042552	myelination
0.44	GO:0009597	detection of virus
0.43	GO:0015825	L-serine transport
0.41	GO:0045087	innate immune response
0.41	GO:0051607	defense response to virus
0.36	GO:1904219	positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity
0.36	GO:1904222	positive regulation of serine C-palmitoyltransferase activity
0.35	GO:0008654	phospholipid biosynthetic process

0.43	GO:0015194	L-serine transmembrane transporter activity
0.33	GO:0030674	protein binding, bridging
0.33	GO:0051537	2 iron, 2 sulfur cluster binding

0.43	GO:0012505	endomembrane system
0.42	GO:0043209	myelin sheath
0.41	GO:0031984	organelle subcompartment
0.39	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0044444	cytoplasmic part
0.36	GO:0005886	plasma membrane
0.34	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

tr|M9PFR6|M9PFR6_DROME
Multiprotein bridging factor 1, isoform E
Search

0.76	Multiprotein bridging factor

0.48	GO:0007424	open tracheal system development
0.47	GO:0043388	positive regulation of DNA binding
0.46	GO:0007417	central nervous system development
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.36	GO:0030154	cell differentiation
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0003158	endothelium development
0.34	GO:0019216	regulation of lipid metabolic process
0.33	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.32	GO:0009966	regulation of signal transduction

0.64	GO:0043565	sequence-specific DNA binding
0.52	GO:0003713	transcription coactivator activity
0.46	GO:0030674	protein binding, bridging
0.37	GO:0005516	calmodulin binding
0.35	GO:0004402	histone acetyltransferase activity
0.34	GO:0008168	methyltransferase activity
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0004864	protein phosphatase inhibitor activity
0.33	GO:0003723	RNA binding

0.45	GO:0005669	transcription factor TFIID complex
0.43	GO:0005730	nucleolus
0.42	GO:0005829	cytosol
0.35	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.35

GO:0004402

tr|M9PFR8|M9PFR8_DROME
Uncharacterized protein, isoform B
Search

0.46	Importin beta-4

0.68	GO:0006886	intracellular protein transport
0.43	GO:0006610	ribosomal protein import into nucleus
0.43	GO:0006607	NLS-bearing protein import into nucleus
0.38	GO:0043248	proteasome assembly
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.79	GO:0008536	Ran GTPase binding
0.43	GO:0008139	nuclear localization sequence binding
0.39	GO:0008565	protein transporter activity
0.34	GO:0043565	sequence-specific DNA binding
0.33	GO:0003700	DNA binding transcription factor activity

0.55	GO:0005634	nucleus
0.38	GO:0012505	endomembrane system
0.38	GO:0031974	membrane-enclosed lumen
0.37	GO:0031967	organelle envelope
0.37	GO:0031090	organelle membrane
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|M9PFS9|M9PFS9_DROME
Uncharacterized protein
Search

tr|M9PFU0|M9PFU0_DROME
Uncharacterized protein, isoform A
Search

0.33	GO:1902476	chloride transmembrane transport
0.33	GO:0009909	regulation of flower development
0.33	GO:0050832	defense response to fungus
0.33	GO:0002009	morphogenesis of an epithelium
0.33	GO:0048608	reproductive structure development
0.33	GO:0009887	animal organ morphogenesis
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression
0.33	GO:0035285	appendage segmentation

0.50	GO:0045735	nutrient reservoir activity
0.36	GO:0003677	DNA binding
0.33	GO:0005254	chloride channel activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0004651	polynucleotide 5'-phosphatase activity
0.33	GO:0005515	protein binding
0.32	GO:0016779	nucleotidyltransferase activity
0.32	GO:0008168	methyltransferase activity
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0005509	calcium ion binding

0.38	GO:0005634	nucleus
0.34	GO:0034707	chloride channel complex
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0005886	plasma membrane
0.32	GO:0044446	intracellular organelle part
0.32	GO:0005911	cell-cell junction
0.32	GO:0005578	proteinaceous extracellular matrix
0.32	GO:0009986	cell surface
0.32	GO:0005829	cytosol
0.32	GO:0043234	protein complex

0.33

EC:3.1.3.33

GO:0004651

tr|M9PFU2|M9PFU2_DROME
CREB-regulated transcription coactivator, isoform B
Search

0.69	Transducer of regulated CREB activity

0.84	GO:0032793	positive regulation of CREB transcription factor activity
0.81	GO:0051289	protein homotetramerization
0.58	GO:0042594	response to starvation
0.54	GO:0006979	response to oxidative stress
0.45	GO:0043970	histone H3-K9 acetylation
0.43	GO:0042593	glucose homeostasis
0.43	GO:1901998	toxin transport
0.42	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:0019319	hexose biosynthetic process
0.41	GO:0006006	glucose metabolic process

0.84	GO:0008140	cAMP response element binding protein binding
0.36	GO:0005254	chloride channel activity
0.35	GO:0003682	chromatin binding
0.35	GO:0001104	RNA polymerase II transcription cofactor activity
0.35	GO:0008270	zinc ion binding
0.35	GO:0003676	nucleic acid binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.40	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part
0.36	GO:0034707	chloride channel complex
0.35	GO:0033588	Elongator holoenzyme complex
0.35	GO:0070062	extracellular exosome
0.33	GO:0005886	plasma membrane
0.33	GO:1905369	endopeptidase complex
0.33	GO:0098588	bounding membrane of organelle

0.33

EC:2.6.1

GO:0008483

tr|M9PFU4|M9PFU4_DROME
Uncharacterized protein
Search

tr|M9PFU5|M9PFU5_DROME
Uncharacterized protein, isoform K
Search

0.47

GO:0006413

translational initiation

0.56	GO:0016874	ligase activity
0.48	GO:0003743	translation initiation factor activity

0.30

GO:0031224

intrinsic component of membrane

0.56

GO:0016874

tr|M9PFV3|M9PFV3_DROME
Nimrod B1, isoform B
Search

0.47	von Willebrand factor D and EGF domain-containing protein

0.51	GO:0042742	defense response to bacterium
0.51	GO:0006909	phagocytosis
0.37	GO:0007154	cell communication
0.37	GO:0007275	multicellular organism development
0.33	GO:0023052	signaling
0.33	GO:0065007	biological regulation
0.33	GO:0051716	cellular response to stimulus

0.44	GO:0005509	calcium ion binding
0.36	GO:0005201	extracellular matrix structural constituent
0.33	GO:0008270	zinc ion binding
0.33	GO:0003700	DNA binding transcription factor activity

0.40	GO:0005886	plasma membrane
0.39	GO:0005576	extracellular region
0.34	GO:0045095	keratin filament
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|M9PFV8|M9PFV8_DROME
Regeneration, isoform B
Search

0.52	Regeneration, isoform B

0.76	GO:0042246	tissue regeneration
0.41	GO:0006402	mRNA catabolic process
0.40	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.40	GO:0006364	rRNA processing
0.39	GO:0008033	tRNA processing
0.37	GO:0043213	bacteriocin transport
0.37	GO:0009405	pathogenesis
0.36	GO:0071108	protein K48-linked deubiquitination
0.36	GO:0032456	endocytic recycling
0.35	GO:0006936	muscle contraction

0.48	GO:0030246	carbohydrate binding
0.43	GO:0008995	ribonuclease E activity
0.40	GO:0004521	endoribonuclease activity
0.39	GO:0008270	zinc ion binding
0.39	GO:0000287	magnesium ion binding
0.38	GO:0003723	RNA binding
0.37	GO:0005509	calcium ion binding
0.37	GO:0019784	NEDD8-specific protease activity
0.36	GO:0005515	protein binding
0.36	GO:0004843	thiol-dependent ubiquitin-specific protease activity

0.42	GO:0009898	cytoplasmic side of plasma membrane
0.36	GO:0005737	cytoplasm
0.35	GO:0005634	nucleus
0.35	GO:0044430	cytoskeletal part
0.34	GO:0015629	actin cytoskeleton
0.34	GO:0012505	endomembrane system
0.34	GO:0019867	outer membrane
0.34	GO:0000777	condensed chromosome kinetochore
0.33	GO:0030686	90S preribosome
0.33	GO:0030687	preribosome, large subunit precursor

0.33	EC:3.4.22	GO:0004197
0.34	KEGG:R03876	GO:0004842

tr|M9PFX3|M9PFX3_DROME
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|M9PFX4|M9PFX4_DROME
Cuticular protein 76Bd, isoform C
Search

0.80	endochitinase A

0.46

GO:0040003

chitin-based cuticle development

0.77	GO:0042302	structural constituent of cuticle
0.32	GO:0016757	transferase activity, transferring glycosyl groups

0.43	GO:0031012	extracellular matrix
0.32	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016757

tr|M9PFY3|M9PFY3_DROME
Uncharacterized protein, isoform C
Search

0.71	Ankyrin repeat and BTB/POZ domain-containing protein 2

0.41	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.40	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.40	GO:0030162	regulation of proteolysis
0.33	GO:0060395	SMAD protein signal transduction

0.74	GO:0046982	protein heterodimerization activity
0.41	GO:0031625	ubiquitin protein ligase binding
0.38	GO:0003677	DNA binding
0.33	GO:0070001	aspartic-type peptidase activity
0.33	GO:0004175	endopeptidase activity

0.44	GO:0000786	nucleosome
0.42	GO:0019005	SCF ubiquitin ligase complex
0.40	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|M9PFZ1|M9PFZ1_DROME
Nopp140, isoform E
Search

NOLC1

0.64	Treacher Collins-Franceschetti syndrome 1 transcript variant 2

0.63	GO:0000451	rRNA 2'-O-methylation
0.46	GO:0048562	embryonic organ morphogenesis
0.45	GO:1904888	cranial skeletal system development
0.44	GO:0048706	embryonic skeletal system development
0.44	GO:0048705	skeletal system morphogenesis
0.42	GO:0001522	pseudouridine synthesis
0.40	GO:0009303	rRNA transcription
0.40	GO:0061371	determination of heart left/right asymmetry
0.40	GO:0035050	embryonic heart tube development
0.40	GO:0003007	heart morphogenesis

0.48	GO:0003723	RNA binding
0.36	GO:0008168	methyltransferase activity
0.36	GO:0046872	metal ion binding
0.34	GO:0031369	translation initiation factor binding
0.33	GO:0043022	ribosome binding
0.33	GO:0003677	DNA binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding

0.62	GO:0005730	nucleolus
0.45	GO:0072588	box H/ACA RNP complex
0.39	GO:1902494	catalytic complex
0.37	GO:0019013	viral nucleocapsid
0.36	GO:0015030	Cajal body
0.34	GO:0010494	cytoplasmic stress granule
0.34	GO:0022627	cytosolic small ribosomal subunit
0.34	GO:0033290	eukaryotic 48S preinitiation complex
0.33	GO:0044427	chromosomal part
0.33	GO:0044815	DNA packaging complex

0.36

GO:0008168

tr|M9PG08|M9PG08_DROME
Rho-related BTB domain containing, isoform B
Search

0.68	G protein RhoBTB

0.76	GO:0007264	small GTPase mediated signal transduction
0.53	GO:0035011	melanotic encapsulation of foreign target
0.33	GO:0051056	regulation of small GTPase mediated signal transduction

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.45	GO:0005622	intracellular
0.32	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|M9PG15|M9PG15_DROME
Secretory pathway calcium atpase, isoform G
Search

0.34	Secretory pathway calcium atpase, isoform G

0.87	GO:0051208	sequestering of calcium ion
0.84	GO:0042044	fluid transport
0.84	GO:0019722	calcium-mediated signaling
0.83	GO:0071421	manganese ion transmembrane transport
0.77	GO:0070588	calcium ion transmembrane transport
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport

0.87	GO:0015410	manganese-transporting ATPase activity
0.81	GO:0005388	calcium-transporting ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.76	GO:0005777	peroxisome
0.72	GO:0005794	Golgi apparatus
0.70	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.87

EC:3.6.3.35

GO:0015410

tr|M9PG24|M9PG24_DROME
Uncharacterized protein
Search

tr|M9PG41|M9PG41_DROME
Uncharacterized protein
Search

tr|M9PG65|M9PG65_DROME
Seminal fluid protein 78E, isoform B
Search

0.20	Seminal fluid protein 78E, isoform B

0.77

GO:0032504

multicellular organism reproduction

0.73

GO:0005615

extracellular space

tr|M9PG80|M9PG80_DROME
Traffic jam, isoform C
Search

0.95	Traffic jam

0.62	GO:0035262	gonad morphogenesis
0.60	GO:0007298	border follicle cell migration
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0006351	transcription, DNA-templated
0.56	GO:0001708	cell fate specification
0.54	GO:0051254	positive regulation of RNA metabolic process
0.54	GO:0010557	positive regulation of macromolecule biosynthetic process
0.54	GO:0031328	positive regulation of cellular biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.43	GO:0046982	protein heterodimerization activity
0.39	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0043522	leucine zipper domain binding
0.33	GO:0003713	transcription coactivator activity
0.33	GO:0042803	protein homodimerization activity
0.32	GO:0016829	lyase activity
0.32	GO:0003735	structural constituent of ribosome
0.32	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.32	GO:0005829	cytosol
0.32	GO:0043233	organelle lumen
0.32	GO:0005840	ribosome
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.32

EC:4

GO:0016829

tr|M9PG91|M9PG91_DROME
Uncharacterized protein
Search

tr|M9PG98|M9PG98_DROME
alpha-1,2-Mannosidase
Search

0.39	alpha-1,2-Mannosidase

0.60	GO:0097466	ubiquitin-dependent glycoprotein ERAD pathway
0.56	GO:0030968	endoplasmic reticulum unfolded protein response
0.52	GO:0036509	trimming of terminal mannose on B branch
0.52	GO:0008340	determination of adult lifespan
0.52	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol
0.50	GO:0035977	protein deglycosylation involved in glycoprotein catabolic process
0.45	GO:0006491	N-glycan processing
0.35	GO:0036512	trimming of second mannose on A branch
0.35	GO:0036511	trimming of first mannose on A branch
0.35	GO:0036510	trimming of terminal mannose on C branch

0.82	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.70	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding

0.51	GO:0005783	endoplasmic reticulum
0.40	GO:0044446	intracellular organelle part
0.33	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

0.82	EC:3.2.1.113	GO:0004571
0.82	KEGG:R05982 KEGG:R06722	GO:0004571

tr|M9PG99|M9PG99_DROME
Uncharacterized protein, isoform B
Search

tr|M9PGC0|M9PGC0_DROME
M6, isoform F
Search

0.52	Myelin proteolipid

0.55	GO:0046956	positive phototaxis
0.51	GO:0001745	compound eye morphogenesis
0.50	GO:0048477	oogenesis
0.33	GO:0006508	proteolysis

0.34	GO:0008234	cysteine-type peptidase activity
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

0.40	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.34

GO:0008234

tr|M9PGC5|M9PGC5_DROME
Wnk kinase, isoform M
Search

WNK

0.96	Wnk kinase, isoform M

0.68	GO:1903288	positive regulation of potassium ion import
0.63	GO:0006468	protein phosphorylation
0.60	GO:0007411	axon guidance
0.59	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.59	GO:0035220	wing disc development
0.34	GO:0000186	activation of MAPKK activity
0.34	GO:0006338	chromatin remodeling
0.34	GO:0035556	intracellular signal transduction
0.32	GO:2000651	positive regulation of sodium ion transmembrane transporter activity
0.32	GO:0070373	negative regulation of ERK1 and ERK2 cascade

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.31	GO:0046872	metal ion binding

0.37	GO:0005737	cytoplasm
0.34	GO:0070603	SWI/SNF superfamily-type complex
0.31	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0004674

tr|M9PGD0|M9PGD0_DROME
CG3711, isoform D
Search

LZTR1

0.72	Leucine zipper like transcription regulator 1

0.40	GO:0006281	DNA repair
0.36	GO:0055114	oxidation-reduction process

0.42	GO:0008094	DNA-dependent ATPase activity
0.41	GO:0051537	2 iron, 2 sulfur cluster binding
0.39	GO:0050660	flavin adenine dinucleotide binding
0.39	GO:0003723	RNA binding
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0003677	DNA binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0046872	metal ion binding

0.41	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0016491

tr|M9PGG2|M9PGG2_DROME
Jim, isoform F
Search

0.43	GO:0048813	dendrite morphogenesis
0.43	GO:0031935	regulation of chromatin silencing
0.32	GO:0006508	proteolysis

0.51	GO:0003676	nucleic acid binding
0.34	GO:0003779	actin binding
0.33	GO:0004252	serine-type endopeptidase activity
0.32	GO:0046872	metal ion binding

0.30

GO:0016020

membrane

0.33

GO:0004252

tr|M9PGG8|M9PGG8_DROME
Uncharacterized protein, isoform B
Search

0.59	caltractin

0.40	GO:0000226	microtubule cytoskeleton organization
0.39	GO:0022027	interkinetic nuclear migration
0.39	GO:0034605	cellular response to heat
0.39	GO:0070925	organelle assembly
0.38	GO:0032465	regulation of cytokinesis
0.37	GO:0044782	cilium organization
0.37	GO:0120031	plasma membrane bounded cell projection assembly
0.37	GO:0006289	nucleotide-excision repair
0.36	GO:0007049	cell cycle
0.35	GO:0007283	spermatogenesis

0.70	GO:0005509	calcium ion binding
0.43	GO:0032795	heterotrimeric G-protein binding
0.40	GO:0031683	G-protein beta/gamma-subunit complex binding
0.40	GO:0016174	NAD(P)H oxidase activity
0.39	GO:0008017	microtubule binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity

0.45	GO:0005814	centriole
0.44	GO:0005813	centrosome
0.42	GO:0000922	spindle pole
0.42	GO:0032391	photoreceptor connecting cilium
0.39	GO:0071942	XPC complex
0.35	GO:0036064	ciliary basal body
0.34	GO:0030008	TRAPP complex
0.30	GO:0016020	membrane

0.40

EC:1.6.3.1

GO:0016174

tr|M9PGH7|M9PGH7_DROME
G9a, isoform B
Search

0.57	Euchromatic histone-lysine N-methyltransferase

0.79	GO:0034968	histone lysine methylation
0.69	GO:1900111	positive regulation of histone H3-K9 dimethylation
0.69	GO:0046959	habituation
0.68	GO:0008345	larval locomotory behavior
0.68	GO:0007614	short-term memory
0.68	GO:0035076	ecdysone receptor-mediated signaling pathway
0.67	GO:0050775	positive regulation of dendrite morphogenesis
0.67	GO:0061647	histone H3-K9 modification
0.66	GO:0007616	long-term memory
0.65	GO:0050688	regulation of defense response to virus

0.79	GO:0018024	histone-lysine N-methyltransferase activity
0.63	GO:0008270	zinc ion binding
0.59	GO:0002039	p53 binding
0.35	GO:0003924	GTPase activity
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0032561	guanyl ribonucleotide binding
0.34	GO:0003677	DNA binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005549	odorant binding
0.32	GO:0004674	protein serine/threonine kinase activity

0.67	GO:0005705	polytene chromosome interband
0.65	GO:0000791	euchromatin
0.61	GO:0005634	nucleus

0.79

GO:0018024

tr|M9PGH9|M9PGH9_DROME
Ca[2+]-channel protein alpha[[1]] subunit T, isoform F
Search

CA-ALPHA1T

0.54	Voltage-dependent T-type calcium channel subunit alpha

0.71	GO:0070588	calcium ion transmembrane transport
0.54	GO:0034765	regulation of ion transmembrane transport
0.42	GO:0019228	neuronal action potential
0.42	GO:0086010	membrane depolarization during action potential
0.40	GO:0035725	sodium ion transmembrane transport
0.39	GO:0070509	calcium ion import
0.37	GO:0030488	tRNA methylation
0.32	GO:0071805	potassium ion transmembrane transport

0.75	GO:0005245	voltage-gated calcium channel activity
0.42	GO:0005248	voltage-gated sodium channel activity
0.39	GO:0016428	tRNA (cytosine-5-)-methyltransferase activity
0.35	GO:0003723	RNA binding
0.32	GO:0005249	voltage-gated potassium channel activity

0.72	GO:0005891	voltage-gated calcium channel complex
0.37	GO:0005887	integral component of plasma membrane
0.32	GO:0034705	potassium channel complex

0.39

GO:0016428

tr|M9PGI6|M9PGI6_DROME
Sec22 ortholog, isoform B
Search

0.81	Vesicle transport protein SEC22

0.67	GO:0016192	vesicle-mediated transport
0.50	GO:0061355	Wnt protein secretion
0.41	GO:0090174	organelle membrane fusion
0.41	GO:0016050	vesicle organization
0.38	GO:0046907	intracellular transport
0.34	GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process
0.33	GO:0008643	carbohydrate transport
0.33	GO:1902600	hydrogen ion transmembrane transport

0.41	GO:0005484	SNAP receptor activity
0.40	GO:0000149	SNARE binding
0.34	GO:0004326	tetrahydrofolylpolyglutamate synthase activity
0.34	GO:0005351	sugar:proton symporter activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0031201	SNARE complex
0.37	GO:0012507	ER to Golgi transport vesicle membrane
0.37	GO:0000139	Golgi membrane
0.35	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.34

EC:6.3.2.17

GO:0004326

tr|M9PGK1|M9PGK1_DROME
CG3655, isoform C
Search

0.20	Glycosyl transferase

0.38

GO:0006491

N-glycan processing

0.39

GO:0016740

transferase activity

0.33	GO:0043229	intracellular organelle
0.30	GO:0031224	intrinsic component of membrane

0.39

GO:0016740

tr|M9PGK3|M9PGK3_DROME
Uncharacterized protein, isoform I
Search

0.50	GO:0007018	microtubule-based movement
0.42	GO:0016310	phosphorylation
0.41	GO:0006338	chromatin remodeling
0.39	GO:0035314	scab formation
0.39	GO:0035165	embryonic crystal cell differentiation
0.39	GO:0007486	imaginal disc-derived female genitalia development
0.39	GO:0042675	compound eye cone cell differentiation
0.39	GO:0046672	positive regulation of compound eye retinal cell programmed cell death
0.39	GO:0045467	R7 cell development
0.38	GO:0000122	negative regulation of transcription by RNA polymerase II

0.50	GO:0003777	microtubule motor activity
0.43	GO:0016301	kinase activity
0.37	GO:0003676	nucleic acid binding
0.36	GO:0008658	penicillin binding
0.35	GO:0003700	DNA binding transcription factor activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046872	metal ion binding

0.47	GO:0046695	SLIK (SAGA-like) complex
0.46	GO:0000124	SAGA complex
0.46	GO:0005669	transcription factor TFIID complex
0.41	GO:0070603	SWI/SNF superfamily-type complex
0.30	GO:0016020	membrane

tr|M9PGK7|M9PGK7_DROME
Klarsicht, isoform E
Search

KLAR

0.95	serine-rich adhesin for platelets isoform X2

0.75	GO:0045855	negative regulation of pole plasm oskar mRNA localization
0.73	GO:0031887	lipid droplet transport along microtubule
0.72	GO:0007523	larval visceral muscle development
0.72	GO:0060361	flight
0.71	GO:0035149	lumen formation, open tracheal system
0.70	GO:0048085	adult chitin-containing cuticle pigmentation
0.69	GO:0042051	compound eye photoreceptor development
0.68	GO:0007097	nuclear migration
0.67	GO:0034453	microtubule anchoring
0.65	GO:0006997	nucleus organization

0.67

GO:0019894

kinesin binding

0.69	GO:0005640	nuclear outer membrane
0.66	GO:0005881	cytoplasmic microtubule
0.65	GO:0005811	lipid droplet
0.63	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016021	integral component of membrane

tr|M9PGQ5|M9PGQ5_DROME
Uncharacterized protein, isoform C
Search

0.62

GO:0044255

cellular lipid metabolic process

0.68

GO:0052689

carboxylic ester hydrolase activity

0.30

GO:0016021

integral component of membrane

0.68	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.68	KEGG:R00630	GO:0052689

tr|M9PGR0|M9PGR0_DROME
Dorsal interacting protein 1, isoform B
Search

DLIP1

0.95	Dorsal interacting protein 1

0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.44	GO:0042802	identical protein binding

0.61

GO:0005634

nucleus

tr|M9PGT2|M9PGT2_DROME
Uncharacterized protein, isoform C
Search

0.44	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|M9PGY6|M9PGY6_DROME
CG2278, isoform B
Search

0.56	GO:0006468	protein phosphorylation
0.42	GO:0060255	regulation of macromolecule metabolic process
0.42	GO:0031323	regulation of cellular metabolic process
0.42	GO:0051171	regulation of nitrogen compound metabolic process
0.42	GO:0080090	regulation of primary metabolic process
0.41	GO:0032502	developmental process
0.41	GO:0009889	regulation of biosynthetic process
0.40	GO:0051347	positive regulation of transferase activity
0.40	GO:0032501	multicellular organismal process
0.40	GO:1902533	positive regulation of intracellular signal transduction

0.56	GO:0004672	protein kinase activity
0.49	GO:0030554	adenyl nucleotide binding
0.48	GO:0097367	carbohydrate derivative binding
0.48	GO:0008144	drug binding
0.48	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0019901	protein kinase binding
0.41	GO:0005057	signal transducer activity, downstream of receptor
0.39	GO:0140110	transcription regulator activity
0.39	GO:0003676	nucleic acid binding
0.38	GO:0003682	chromatin binding

0.40	GO:0005634	nucleus
0.36	GO:0005703	polytene chromosome puff
0.36	GO:0005705	polytene chromosome interband
0.35	GO:0035327	transcriptionally active chromatin
0.35	GO:0000178	exosome (RNase complex)
0.35	GO:0000932	P-body
0.34	GO:0005667	transcription factor complex
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.35

GO:0042578

tr|M9PGZ8|M9PGZ8_DROME
Smrter, isoform G
Search

SMR

0.95	SANT domain protein SMRTER

0.68	GO:0045746	negative regulation of Notch signaling pathway
0.66	GO:0030707	ovarian follicle cell development
0.61	GO:0007346	regulation of mitotic cell cycle
0.53	GO:0045892	negative regulation of transcription, DNA-templated
0.43	GO:0006357	regulation of transcription by RNA polymerase II

0.62	GO:0003682	chromatin binding
0.59	GO:0003714	transcription corepressor activity
0.55	GO:0003677	DNA binding
0.50	GO:0016922	ligand-dependent nuclear receptor binding

0.67	GO:0005700	polytene chromosome
0.65	GO:0017053	transcriptional repressor complex
0.60	GO:0005634	nucleus
0.52	GO:0005829	cytosol
0.51	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.41	GO:1902494	catalytic complex
0.30	GO:0031224	intrinsic component of membrane

tr|M9PH18|M9PH18_DROME
Uncharacterized protein, isoform B
Search

0.10

mucin-2

0.37

GO:0006030

chitin metabolic process

0.49	GO:0042302	structural constituent of cuticle
0.37	GO:0008061	chitin binding

0.36	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|M9PH26|M9PH26_DROME
Helix loop helix protein 4C, isoform B
Search

0.68	helix-loop-helix protein 1

0.48	GO:0006366	transcription by RNA polymerase II
0.48	GO:0006357	regulation of transcription by RNA polymerase II
0.47	GO:0045893	positive regulation of transcription, DNA-templated
0.43	GO:0007617	mating behavior
0.43	GO:0042698	ovulation cycle
0.36	GO:0030154	cell differentiation
0.35	GO:0007275	multicellular organism development
0.34	GO:0051091	positive regulation of DNA binding transcription factor activity

0.68	GO:0046983	protein dimerization activity
0.51	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.50	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.43	GO:0001102	RNA polymerase II activating transcription factor binding
0.42	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.42	GO:0000987	proximal promoter sequence-specific DNA binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005634	nucleus
0.33	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

tr|M9PH32|M9PH32_DROME
Meiotic P26, isoform C
Search

0.95	E3 ubiquitin-protein ligase TRIM33 isoform X1

0.53	GO:0007281	germ cell development
0.52	GO:0051321	meiotic cell cycle
0.44	GO:0016567	protein ubiquitination

0.61	GO:0008270	zinc ion binding
0.45	GO:0004842	ubiquitin-protein transferase activity
0.39	GO:0016874	ligase activity
0.35	GO:0003676	nucleic acid binding

0.45

GO:0005622

intracellular

0.39	EC:6	GO:0016874
0.45	KEGG:R03876	GO:0004842

tr|M9PH36|M9PH36_DROME
Uncharacterized protein, isoform E
Search

0.46

GO:0018345

protein palmitoylation

0.69	GO:0016409	palmitoyltransferase activity
0.68	GO:0019707	protein-cysteine S-acyltransferase activity

0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0016409

tr|M9PH63|M9PH63_DROME
Uncharacterized protein, isoform B
Search

0.36

GO:0016310

phosphorylation

0.37

GO:0016301

kinase activity

tr|M9PHA0|M9PHA0_DROME
Bifocal, isoform F
Search

BIF

0.84	Protein phosphatase 1-binding protein Bifocal

0.86	GO:0030517	negative regulation of axon extension
0.81	GO:0007411	axon guidance
0.77	GO:0016321	female meiosis chromosome segregation

0.78	GO:0051015	actin filament binding
0.74	GO:0008017	microtubule binding
0.32	GO:0004386	helicase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0003676	nucleic acid binding

0.49

GO:0005737

cytoplasm

tr|M9PHA4|M9PHA4_DROME
XK-related protein
Search

0.30

GO:0044425

membrane part

tr|M9PHB8|M9PHB8_DROME
Sarcoplasmic calcium-binding protein, isoform C
Search

CBP

0.67	Sarcoplasmic calcium-binding protein, isoform C

0.59

GO:0050829

defense response to Gram-negative bacterium

0.70	GO:0005509	calcium ion binding
0.34	GO:0008270	zinc ion binding
0.33	GO:0003676	nucleic acid binding

0.42	GO:0005654	nucleoplasm
0.41	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|M9PHC0|M9PHC0_DROME
Uncharacterized protein, isoform C
Search

0.30

GO:0044425

membrane part

tr|M9PHF7|M9PHF7_DROME
Uncharacterized protein, isoform C
Search

tr|M9PHH0|M9PHH0_DROME
C12.2, isoform B
Search

0.63	von Willebrand factor A domain-containing protein 8

0.61	GO:0016887	ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.61

GO:0016887

tr|M9PHH9|M9PHH9_DROME
Uncharacterized protein
Search

tr|M9PHI0|M9PHI0_DROME
Hyperkinetic, isoform M
Search

0.97	Hyperkinetic, isoform M

0.72	GO:0071805	potassium ion transmembrane transport
0.60	GO:0050802	circadian sleep/wake cycle, sleep
0.59	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep
0.50	GO:0051259	protein oligomerization
0.47	GO:0065009	regulation of molecular function

0.76	GO:0005249	voltage-gated potassium channel activity
0.57	GO:0015459	potassium channel regulator activity

0.53	GO:0008076	voltage-gated potassium channel complex
0.48	GO:0005737	cytoplasm

tr|M9PHI7|M9PHI7_DROME
Krishah, isoform B
Search

0.40	Uracil phosphoribosyltransferase

0.66	GO:0009116	nucleoside metabolic process
0.41	GO:0008655	pyrimidine-containing compound salvage
0.40	GO:0006206	pyrimidine nucleobase metabolic process
0.40	GO:0009174	pyrimidine ribonucleoside monophosphate biosynthetic process
0.39	GO:0009218	pyrimidine ribonucleotide metabolic process
0.39	GO:0006221	pyrimidine nucleotide biosynthetic process
0.39	GO:1901659	glycosyl compound biosynthetic process
0.38	GO:0009260	ribonucleotide biosynthetic process
0.34	GO:0007595	lactation
0.34	GO:0007565	female pregnancy

0.56	GO:0016757	transferase activity, transferring glycosyl groups
0.42	GO:0004849	uridine kinase activity
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0032561	guanyl ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.39	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.56

GO:0016757

tr|M9PHI8|M9PHI8_DROME
Uncharacterized protein, isoform B
Search

0.10	Regulator of G-protein signaling 7

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.62	GO:0035556	intracellular signal transduction
0.38	GO:0043547	positive regulation of GTPase activity
0.34	GO:0006310	DNA recombination
0.34	GO:0007601	visual perception
0.34	GO:0009968	negative regulation of signal transduction

0.63	GO:0004871	signal transducer activity
0.38	GO:0005096	GTPase activator activity
0.35	GO:0000150	recombinase activity
0.33	GO:0003677	DNA binding
0.33	GO:0005515	protein binding

0.80	GO:1905360	GTPase complex
0.79	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.65	GO:0098797	plasma membrane protein complex
0.36	GO:0001750	photoreceptor outer segment
0.35	GO:0001917	photoreceptor inner segment
0.35	GO:0060170	ciliary membrane
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|M9PHK6|M9PHK6_DROME
Uncharacterized protein, isoform C
Search

0.69	GO:0045454	cell redox homeostasis
0.40	GO:0006165	nucleoside diphosphate phosphorylation

0.42

GO:0004550

nucleoside diphosphate kinase activity

0.34	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

0.42

EC:2.7.4.6

GO:0004550

tr|M9PHM9|M9PHM9_DROME
Uncharacterized protein, isoform A
Search

0.30

GO:0044425

membrane part

tr|M9PHQ2|M9PHQ2_DROME
Histone deacetylase 4, isoform G
Search

0.46	Histone deacetylase

0.80	GO:0070932	histone H3 deacetylation
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0007616	long-term memory
0.55	GO:0010468	regulation of gene expression
0.52	GO:0016573	histone acetylation

0.81	GO:0004407	histone deacetylase activity
0.78	GO:0034979	NAD-dependent protein deacetylase activity
0.52	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding

0.79	GO:0000118	histone deacetylase complex
0.39	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:3.5.1.98

GO:0004407

tr|M9PHR3|M9PHR3_DROME
Uncharacterized protein, isoform B
Search

0.47	GO:0006508	proteolysis
0.39	GO:0007165	signal transduction

0.56	GO:0004181	metallocarboxypeptidase activity
0.48	GO:0008270	zinc ion binding
0.40	GO:0004871	signal transducer activity
0.35	GO:0005509	calcium ion binding

0.44

GO:0031301

integral component of organelle membrane

0.56

EC:3.4.17

GO:0004181

tr|M9PHS6|M9PHS6_DROME
Down syndrome cell adhesion molecule 4, isoform I
Search

0.71	Down syndrome cell adhesion molecule, isoform A

0.39	GO:0007155	cell adhesion
0.34	GO:0048812	neuron projection morphogenesis
0.31	GO:0006260	DNA replication

0.39	GO:0042802	identical protein binding
0.31	GO:0003677	DNA binding

0.38

GO:0005887

integral component of plasma membrane

tr|M9PHS8|M9PHS8_DROME
CG9784, isoform C
Search

0.44	Skeletal muscle and kidney-enriched inositol phosphatase

0.81	GO:0046856	phosphatidylinositol dephosphorylation
0.35	GO:0048741	skeletal muscle fiber development
0.35	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.35	GO:0043010	camera-type eye development
0.33	GO:0007528	neuromuscular junction development
0.33	GO:0061053	somite development
0.33	GO:0007165	signal transduction

0.51

GO:0016787

hydrolase activity

0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.51

GO:0016787

tr|M9PHT1|M9PHT1_DROME
Grunge, isoform J
Search

LOC108088992

0.88	Transcriptional corepressor Atro

0.62	GO:0002121	inter-male aggressive behavior
0.61	GO:0007526	larval somatic muscle development
0.61	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.60	GO:0007480	imaginal disc-derived leg morphogenesis
0.60	GO:0045879	negative regulation of smoothened signaling pathway
0.60	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.58	GO:0035065	regulation of histone acetylation
0.58	GO:0009880	embryonic pattern specification
0.57	GO:0035282	segmentation
0.56	GO:0016575	histone deacetylation

0.59	GO:0070491	repressing transcription factor binding
0.57	GO:0003714	transcription corepressor activity
0.56	GO:0004407	histone deacetylase activity
0.55	GO:0003677	DNA binding
0.43	GO:0034979	NAD-dependent protein deacetylase activity
0.39	GO:0001784	phosphotyrosine residue binding
0.35	GO:0004871	signal transducer activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.60	GO:0005705	polytene chromosome interband
0.32	GO:0005829	cytosol

0.56

EC:3.5.1.98

GO:0004407

tr|M9PHT8|M9PHT8_DROME
CG4991, isoform D
Search

0.38	Amino acid transmembrane transporter

0.39

GO:0003333

amino acid transmembrane transport

0.39	GO:0015171	amino acid transmembrane transporter activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.38	GO:0005774	vacuolar membrane
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|M9PHU0|M9PHU0_DROME
Uncharacterized protein, isoform C
Search

0.77	GO:0035023	regulation of Rho protein signal transduction
0.74	GO:0007480	imaginal disc-derived leg morphogenesis
0.66	GO:0065009	regulation of molecular function
0.55	GO:0046579	positive regulation of Ras protein signal transduction

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.34	GO:0050825	ice binding

tr|M9PHU7|M9PHU7_DROME
Uncharacterized protein, isoform G
Search

0.43	GO:0006417	regulation of translation
0.37	GO:0007288	sperm axoneme assembly
0.37	GO:0007291	sperm individualization
0.37	GO:0007141	male meiosis I
0.37	GO:0008049	male courtship behavior
0.37	GO:0007616	long-term memory
0.37	GO:0008356	asymmetric cell division
0.36	GO:0034250	positive regulation of cellular amide metabolic process
0.36	GO:0034249	negative regulation of cellular amide metabolic process
0.35	GO:0032270	positive regulation of cellular protein metabolic process

0.47	GO:0003730	mRNA 3'-UTR binding
0.47	GO:0045182	translation regulator activity
0.42	GO:0008289	lipid binding
0.35	GO:0043022	ribosome binding
0.35	GO:0042802	identical protein binding
0.34	GO:0008135	translation factor activity, RNA binding

0.46	GO:0012505	endomembrane system
0.38	GO:0043227	membrane-bounded organelle
0.38	GO:0044444	cytoplasmic part
0.37	GO:0044292	dendrite terminus
0.37	GO:0043229	intracellular organelle
0.37	GO:0043679	axon terminus
0.36	GO:0044297	cell body
0.36	GO:1990124	messenger ribonucleoprotein complex
0.36	GO:0097060	synaptic membrane
0.35	GO:0030424	axon

tr|M9PHV4|M9PHV4_DROME
Uncharacterized protein, isoform F
Search

0.30

GO:0044425

membrane part

tr|M9PHV5|M9PHV5_DROME
Glutamate receptor IB, isoform B
Search

0.62	Ionotropic glutamate receptor subunit IB

0.75	GO:0060079	excitatory postsynaptic potential
0.74	GO:0035235	ionotropic glutamate receptor signaling pathway
0.57	GO:0006811	ion transport
0.43	GO:0055085	transmembrane transport
0.34	GO:0009253	peptidoglycan catabolic process
0.32	GO:0006396	RNA processing

0.77	GO:0005234	extracellularly glutamate-gated ion channel activity
0.74	GO:0004970	ionotropic glutamate receptor activity
0.47	GO:0099094	ligand-gated cation channel activity
0.44	GO:0005272	sodium channel activity
0.43	GO:0098782	mechanosensitived potassium channel activity
0.34	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0004000	adenosine deaminase activity
0.32	GO:0003723	RNA binding

0.74	GO:0045211	postsynaptic membrane
0.70	GO:0030054	cell junction
0.49	GO:0008328	ionotropic glutamate receptor complex
0.39	GO:0034703	cation channel complex

0.34

EC:3.5.1.28

GO:0008745

tr|M9PHX0|M9PHX0_DROME
Uncharacterized protein
Search

0.47	GO:0007186	G-protein coupled receptor signaling pathway
0.42	GO:0047497	mitochondrion transport along microtubule
0.42	GO:0061162	establishment of monopolar cell polarity
0.42	GO:0045773	positive regulation of axon extension
0.42	GO:0032387	negative regulation of intracellular transport
0.42	GO:0048675	axon extension
0.41	GO:0016358	dendrite development
0.41	GO:0001578	microtubule bundle formation
0.38	GO:0015074	DNA integration
0.37	GO:0006508	proteolysis

0.47	GO:0004930	G-protein coupled receptor activity
0.42	GO:0005519	cytoskeletal regulatory protein binding
0.39	GO:0008017	microtubule binding
0.38	GO:0008237	metallopeptidase activity
0.34	GO:0003676	nucleic acid binding

0.41	GO:0043197	dendritic spine
0.41	GO:0001750	photoreceptor outer segment
0.41	GO:0014069	postsynaptic density
0.40	GO:0005875	microtubule associated complex
0.39	GO:0030054	cell junction
0.39	GO:0005874	microtubule
0.38	GO:0005829	cytosol
0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|M9PHX2|M9PHX2_DROME
Visgun, isoform E
Search

0.80	LOW QUALITY PROTEIN: sialomucin core protein 24

0.66	GO:0048149	behavioral response to ethanol
0.65	GO:0007616	long-term memory
0.59	GO:0042127	regulation of cell proliferation
0.45	GO:0032504	multicellular organism reproduction
0.42	GO:0061188	negative regulation of chromatin silencing at rDNA
0.42	GO:0033169	histone H3-K9 demethylation
0.39	GO:0006030	chitin metabolic process
0.36	GO:0009250	glucan biosynthetic process
0.35	GO:0070267	oncosis
0.35	GO:0046937	phytochelatin metabolic process

0.42	GO:0032454	histone demethylase activity (H3-K9 specific)
0.41	GO:0035064	methylated histone binding
0.40	GO:0003712	transcription cofactor activity
0.39	GO:0008061	chitin binding
0.38	GO:0046872	metal ion binding
0.37	GO:0052861	glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group
0.36	GO:0046527	glucosyltransferase activity
0.35	GO:0047849	dextransucrase activity
0.35	GO:0016756	glutathione gamma-glutamylcysteinyltransferase activity
0.35	GO:0008168	methyltransferase activity

0.71	GO:0098549	somatic ring canal
0.68	GO:0035324	female germline ring canal
0.56	GO:0031410	cytoplasmic vesicle
0.40	GO:0000776	kinetochore
0.39	GO:0005730	nucleolus
0.38	GO:0070701	mucus layer
0.35	GO:0000779	condensed chromosome, centromeric region
0.34	GO:0005654	nucleoplasm
0.34	GO:0009897	external side of plasma membrane
0.34	GO:0009277	fungal-type cell wall

0.37

EC:3.2.1.6

GO:0052861

tr|M9PHY7|M9PHY7_DROME
Suppressor of cytokine signaling at 16D, isoform B
Search

SOCS16D

0.92	Suppressor of cytokine signaling at 16D, isoform B

0.61	GO:0035556	intracellular signal transduction
0.54	GO:0040008	regulation of growth
0.52	GO:0016567	protein ubiquitination
0.44	GO:0046426	negative regulation of JAK-STAT cascade
0.42	GO:0006469	negative regulation of protein kinase activity
0.42	GO:0019221	cytokine-mediated signaling pathway
0.40	GO:0010498	proteasomal protein catabolic process
0.40	GO:0050868	negative regulation of T cell activation
0.33	GO:0043687	post-translational protein modification
0.33	GO:0001678	cellular glucose homeostasis

0.57	GO:0017022	myosin binding
0.43	GO:0004860	protein kinase inhibitor activity
0.32	GO:0008270	zinc ion binding
0.31	GO:0003676	nucleic acid binding

0.44	GO:0005622	intracellular
0.42	GO:0001772	immunological synapse
0.30	GO:0016021	integral component of membrane

tr|M9PHZ1|M9PHZ1_DROME
Transcriptional adaptor 3, isoform C
Search

0.92	transcriptional adapter 3-B

0.84	GO:0043970	histone H3-K9 acetylation
0.84	GO:0044154	histone H3-K14 acetylation
0.84	GO:0043983	histone H4-K12 acetylation
0.84	GO:0043987	histone H3-S10 phosphorylation
0.83	GO:0048096	chromatin-mediated maintenance of transcription
0.81	GO:0035066	positive regulation of histone acetylation
0.45	GO:0006357	regulation of transcription by RNA polymerase II

0.75	GO:0004402	histone acetyltransferase activity
0.72	GO:0003682	chromatin binding
0.48	GO:0003713	transcription coactivator activity
0.40	GO:0005515	protein binding
0.36	GO:0042302	structural constituent of cuticle

0.82	GO:0005703	polytene chromosome puff
0.82	GO:0005705	polytene chromosome interband
0.80	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.75	GO:0000124	SAGA complex

0.75

GO:0004402

tr|M9PI02|M9PI02_DROME
Beadex, isoform D
Search

0.78	Rhombotin-1

0.54	GO:0035483	gastric emptying
0.52	GO:0036011	imaginal disc-derived leg segmentation
0.51	GO:0042220	response to cocaine
0.51	GO:0022416	chaeta development
0.51	GO:0045475	locomotor rhythm
0.50	GO:0007476	imaginal disc-derived wing morphogenesis
0.50	GO:0008593	regulation of Notch signaling pathway
0.46	GO:1903508	positive regulation of nucleic acid-templated transcription
0.46	GO:0010628	positive regulation of gene expression
0.45	GO:0022414	reproductive process

0.54	GO:0046872	metal ion binding
0.38	GO:0005515	protein binding
0.32	GO:0016740	transferase activity

0.38

GO:0005634

nucleus

0.32

GO:0016740

tr|M9PI06|M9PI06_DROME
Uncharacterized protein, isoform B
Search

0.46	Mechanosensory protein 2

0.44

GO:0097206

nephrocyte filtration

0.33

GO:0005515

protein binding

0.35	GO:0005917	nephrocyte diaphragm
0.30	GO:0044425	membrane part

tr|M9PI08|M9PI08_DROME
RunxA, isoform D
Search

RUNXA

0.72	RunxA, isoform D

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0048813	dendrite morphogenesis
0.33	GO:0051254	positive regulation of RNA metabolic process
0.33	GO:0010557	positive regulation of macromolecule biosynthetic process
0.33	GO:0031328	positive regulation of cellular biosynthetic process
0.32	GO:0006351	transcription, DNA-templated

0.60	GO:0003700	DNA binding transcription factor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|M9PI14|M9PI14_DROME
N(Alpha)-acetyltransferase 20, isoform B
Search

0.28	N-alpha-acetyltransferase

0.46	GO:0006473	protein acetylation
0.45	GO:0018206	peptidyl-methionine modification
0.43	GO:0031365	N-terminal protein amino acid modification
0.42	GO:0043524	negative regulation of neuron apoptotic process
0.41	GO:0051604	protein maturation
0.41	GO:0016570	histone modification
0.40	GO:0018205	peptidyl-lysine modification
0.34	GO:0000001	mitochondrion inheritance
0.34	GO:0030433	ubiquitin-dependent ERAD pathway
0.34	GO:0032956	regulation of actin cytoskeleton organization

0.68	GO:0008080	N-acetyltransferase activity
0.34	GO:0016433	rRNA (adenine) methyltransferase activity

0.50	GO:0031416	NatB complex
0.35	GO:0005634	nucleus
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.68

GO:0008080

tr|M9PI24|M9PI24_DROME
Anoctamin
Search

0.62

Anoctamin

0.38	GO:1902476	chloride transmembrane transport
0.32	GO:0061588	calcium activated phospholipid scrambling
0.30	GO:0008152	metabolic process

0.68	GO:0046983	protein dimerization activity
0.41	GO:0061778	intracellular chloride channel activity
0.38	GO:0022839	ion gated channel activity
0.38	GO:0008381	mechanosensitive ion channel activity
0.30	GO:0003824	catalytic activity

0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|M9PI37|M9PI37_DROME
Sodium chloride cotransporter 69, isoform E
Search

0.34	Bumetanide-sensitive sodium-(Potassium)-chloride cotransporter

0.72	GO:1902476	chloride transmembrane transport
0.48	GO:0006813	potassium ion transport
0.38	GO:0003333	amino acid transmembrane transport

0.80	GO:0015377	cation:chloride symporter activity
0.38	GO:0015171	amino acid transmembrane transporter activity

0.41	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|M9PI41|M9PI41_DROME
Sticky, isoform B
Search

0.69	Citron Rho-interacting kinase

0.68	GO:0000281	mitotic cytokinesis
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.60	GO:2000431	regulation of cytokinesis, actomyosin contractile ring assembly
0.60	GO:0007112	male meiosis cytokinesis
0.58	GO:0044837	actomyosin contractile ring organization
0.58	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis
0.51	GO:0006325	chromatin organization
0.46	GO:0051402	neuron apoptotic process
0.46	GO:0007419	ventral cord development

0.70	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0046872	metal ion binding
0.46	GO:0097110	scaffold protein binding
0.46	GO:0030165	PDZ domain binding
0.35	GO:0017048	Rho GTPase binding
0.34	GO:0017124	SH3 domain binding

0.57	GO:0005826	actomyosin contractile ring
0.36	GO:0097610	cell surface furrow
0.36	GO:0030496	midbody
0.36	GO:0043025	neuronal cell body
0.36	GO:0031985	Golgi cisterna
0.35	GO:0001726	ruffle
0.35	GO:0005773	vacuole
0.33	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane

0.70

GO:0004674

tr|M9PI45|M9PI45_DROME
Mirror, isoform C
Search

0.84	homeobox protein caupolican

0.65	GO:0045317	equator specification
0.63	GO:0097374	sensory neuron axon guidance
0.61	GO:0046843	dorsal appendage formation
0.61	GO:0007476	imaginal disc-derived wing morphogenesis
0.60	GO:0045926	negative regulation of growth
0.59	GO:0001700	embryonic development via the syncytial blastoderm
0.59	GO:0007422	peripheral nervous system development
0.58	GO:0007224	smoothened signaling pathway
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.65	GO:0043565	sequence-specific DNA binding
0.54	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.54	GO:0042803	protein homodimerization activity

0.61

GO:0005634

nucleus

tr|M9PI51|M9PI51_DROME
Uncharacterized protein, isoform E
Search

0.66	Dual specificity protein phosphatase 22

0.72	GO:0006470	protein dephosphorylation
0.41	GO:0000188	inactivation of MAPK activity
0.35	GO:0046330	positive regulation of JNK cascade
0.35	GO:0007179	transforming growth factor beta receptor signaling pathway
0.35	GO:0042127	regulation of cell proliferation
0.33	GO:0016310	phosphorylation

0.78	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.43	GO:0004725	protein tyrosine phosphatase activity
0.41	GO:0033549	MAP kinase phosphatase activity
0.34	GO:0005515	protein binding
0.33	GO:0016301	kinase activity

0.35	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.78

GO:0008138

tr|M9PI57|M9PI57_DROME
Nanchung, isoform B
Search

0.67	TRP channel protein nanchung

0.60	GO:0034220	ion transmembrane transport
0.60	GO:0009270	response to humidity
0.60	GO:0048060	negative gravitaxis
0.57	GO:0050884	neuromuscular process controlling posture
0.57	GO:0010996	response to auditory stimulus
0.57	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch
0.57	GO:0001964	startle response
0.57	GO:0007628	adult walking behavior
0.54	GO:0007605	sensory perception of sound
0.41	GO:0006816	calcium ion transport

0.70	GO:0005216	ion channel activity
0.41	GO:0015085	calcium ion transmembrane transporter activity
0.35	GO:0005515	protein binding
0.32	GO:0015081	sodium ion transmembrane transporter activity

0.39	GO:0034703	cation channel complex
0.37	GO:0005887	integral component of plasma membrane
0.34	GO:0097730	non-motile cilium

tr|M9PI70|M9PI70_DROME
pH-sensitive chloride channel, isoform N
Search

0.97	pH-sensitive chloride channel, isoform N

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.44	GO:0006821	chloride transport

0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0099600	transmembrane receptor activity
0.65	GO:0038023	signaling receptor activity
0.50	GO:0061797	pH-gated chloride channel activity

0.55	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|M9PI93|M9PI93_DROME
Uncharacterized protein, isoform E
Search

tr|M9PI97|M9PI97_DROME
Misexpression suppressor of ras 6, isoform B
Search

0.84

GO:0046580

negative regulation of Ras protein signal transduction

tr|M9PIC9|M9PIC9_DROME
Spc105-related, isoform B
Search

0.84	GO:0051382	kinetochore assembly
0.83	GO:0008608	attachment of spindle microtubules to kinetochore

0.82

GO:0000940

condensed chromosome outer kinetochore

tr|M9PID8|M9PID8_DROME
Adenylyl cyclase 78C, isoform E
Search

AC78C

0.77	adenylate cyclase type 8

0.76	GO:0006171	cAMP biosynthetic process
0.75	GO:0010353	response to trehalose
0.73	GO:0001582	detection of chemical stimulus involved in sensory perception of sweet taste
0.73	GO:0031000	response to caffeine
0.71	GO:0009744	response to sucrose
0.62	GO:0035556	intracellular signal transduction
0.41	GO:0006182	cGMP biosynthetic process
0.36	GO:0043547	positive regulation of GTPase activity
0.32	GO:0006352	DNA-templated transcription, initiation
0.32	GO:2001141	regulation of RNA biosynthetic process

0.76	GO:0004016	adenylate cyclase activity
0.51	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.41	GO:0004383	guanylate cyclase activity
0.36	GO:0005096	GTPase activator activity
0.33	GO:0046982	protein heterodimerization activity
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0043168	anion binding

0.54	GO:0005886	plasma membrane
0.45	GO:0005622	intracellular
0.37	GO:0043234	protein complex
0.32	GO:0061695	transferase complex, transferring phosphorus-containing groups
0.32	GO:0043233	organelle lumen
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.76

EC:4.6.1.1

GO:0004016

tr|M9PIG4|M9PIG4_DROME
Golgi complex-localized glycoprotein 1, isoform B
Search

0.84	Metabotropic GABA-B receptor 1

0.34

GO:0016311

dephosphorylation

0.39	GO:0017134	fibroblast growth factor binding
0.34	GO:0016791	phosphatase activity

0.74	GO:0000139	Golgi membrane
0.48	GO:0000138	Golgi trans cisterna
0.48	GO:0005797	Golgi medial cisterna
0.47	GO:0000137	Golgi cis cisterna
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.1.3 EC:3.1.3.41

GO:0016791

tr|M9PIH9|M9PIH9_DROME
Transcription factor AP-2, isoform D
Search

0.70	Transcription factor AP-2-epsilon

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.53	GO:0048728	proboscis development
0.52	GO:0016348	imaginal disc-derived leg joint morphogenesis
0.52	GO:0002121	inter-male aggressive behavior
0.52	GO:0007548	sex differentiation
0.51	GO:0035215	genital disc development
0.51	GO:0008343	adult feeding behavior
0.51	GO:0008049	male courtship behavior

0.61	GO:0003700	DNA binding transcription factor activity
0.44	GO:0043565	sequence-specific DNA binding
0.43	GO:0044212	transcription regulatory region DNA binding
0.40	GO:0046983	protein dimerization activity
0.39	GO:0003690	double-stranded DNA binding
0.36	GO:0004148	dihydrolipoyl dehydrogenase activity
0.34	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.39	GO:0043233	organelle lumen
0.38	GO:0005739	mitochondrion
0.37	GO:0044446	intracellular organelle part
0.32	GO:0005829	cytosol

0.36

EC:1.8.1.4

GO:0004148

tr|M9PIM3|M9PIM3_DROME
Uncharacterized protein
Search

0.47	GO:0007166	cell surface receptor signaling pathway
0.47	GO:0007186	G-protein coupled receptor signaling pathway

0.47

GO:0004930

G-protein coupled receptor activity

0.30

GO:0044425

membrane part

tr|M9PIQ9|M9PIQ9_DROME
Uncharacterized protein, isoform C
Search

0.30

GO:0044425

membrane part

tr|M9PJ12|M9PJ12_DROME
Uncharacterized protein, isoform E
Search

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.34	GO:0016310	phosphorylation
0.30	GO:0051253	negative regulation of RNA metabolic process
0.30	GO:0009890	negative regulation of biosynthetic process

0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.35	GO:0016301	kinase activity

0.61	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|M9PJ28|M9PJ28_DROME
Uncharacterized protein, isoform B
Search

tr|M9PJG1|M9PJG1_DROME
Sp1, isoform F
Search

SP9

0.77	Sp zinc finger transcription factor

0.56	GO:0035107	appendage morphogenesis
0.50	GO:0007478	leg disc morphogenesis
0.49	GO:0060173	limb development
0.49	GO:0048737	imaginal disc-derived appendage development
0.47	GO:0048598	embryonic morphogenesis
0.43	GO:0009954	proximal/distal pattern formation
0.43	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway
0.43	GO:0033339	pectoral fin development
0.43	GO:0009953	dorsal/ventral pattern formation
0.42	GO:1903506	regulation of nucleic acid-templated transcription

0.51	GO:0003676	nucleic acid binding
0.44	GO:0003700	DNA binding transcription factor activity
0.34	GO:0046872	metal ion binding

0.42	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|M9PJJ5|M9PJJ5_DROME
Uncharacterized protein
Search

0.40	Pyridoxal phosphate phosphatase

0.47	GO:0016311	dephosphorylation
0.36	GO:0006464	cellular protein modification process

0.51	GO:0016787	hydrolase activity
0.39	GO:0046983	protein dimerization activity
0.36	GO:0140096	catalytic activity, acting on a protein

0.39	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.51

GO:0016787

tr|M9PJN5|M9PJN5_DROME
Histone deacetylase 6, isoform G
Search

HDAC6

0.54	Histone deacetylase

0.80	GO:0070932	histone H3 deacetylation
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.54	GO:0099643	signal release from synapse
0.54	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.51	GO:0006836	neurotransmitter transport
0.50	GO:0001505	regulation of neurotransmitter levels
0.49	GO:0006099	tricarboxylic acid cycle

0.80	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
0.60	GO:0008270	zinc ion binding
0.34	GO:0033819	lipoyl(octanoyl) transferase activity
0.33	GO:0008408	3'-5' exonuclease activity
0.32	GO:0003676	nucleic acid binding

0.60	GO:0005634	nucleus
0.53	GO:0098793	presynapse
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.80

EC:3.5.1.98

GO:0032041

tr|M9PJP8|M9PJP8_DROME
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|M9PJQ1|M9PJQ1_DROME
Uncharacterized protein, isoform E
Search

LOC108098079

0.92	endochitinase A isoform X1

0.35

GO:0016310

phosphorylation

0.36

GO:0016301

kinase activity

0.34	GO:0044538	host cell periphery
0.33	GO:0020036	Maurer's cleft
0.30	GO:0031224	intrinsic component of membrane

tr|M9PJR1|M9PJR1_DROME
CG7884, isoform B
Search

0.42	GO:0006030	chitin metabolic process
0.36	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0045991	carbon catabolite activation of transcription
0.35	GO:0048663	neuron fate commitment
0.35	GO:0006606	protein import into nucleus
0.34	GO:0007411	axon guidance
0.34	GO:0006366	transcription by RNA polymerase II

0.42	GO:0008061	chitin binding
0.40	GO:0003723	RNA binding
0.40	GO:0003677	DNA binding
0.36	GO:0050825	ice binding
0.35	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.35	GO:0008270	zinc ion binding
0.34	GO:0001104	RNA polymerase II transcription cofactor activity
0.34	GO:0001067	regulatory region nucleic acid binding

0.40	GO:0005576	extracellular region
0.36	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.33	GO:0043234	protein complex
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|M9PJS6|M9PJS6_DROME
Uncharacterized protein, isoform D
Search

0.11	Transmembrane protein 176A

0.41	GO:0050941	negative regulation of pigment cell differentiation
0.41	GO:0042683	negative regulation of compound eye cone cell fate specification
0.40	GO:0035106	operant conditioning
0.40	GO:0046533	negative regulation of photoreceptor cell differentiation
0.40	GO:0007474	imaginal disc-derived wing vein specification
0.39	GO:0045475	locomotor rhythm
0.39	GO:1904396	regulation of neuromuscular junction development
0.39	GO:0042308	negative regulation of protein import into nucleus
0.39	GO:0008306	associative learning
0.39	GO:0007528	neuromuscular junction development

0.40	GO:0004711	ribosomal protein S6 kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0043204	perikaryon
0.39	GO:0031594	neuromuscular junction
0.38	GO:0098793	presynapse
0.30	GO:0016020	membrane

0.40

GO:0004711

tr|N0ACE7|N0ACE7_DROME
GH11688p2
Search

sp|O01346|EGH_DROME
Beta-1,4-mannosyltransferase egh
Search

0.35	Glycosphingolipid synthetase

0.78	GO:0097502	mannosylation
0.50	GO:0042248	maintenance of polarity of follicular epithelium
0.49	GO:0001744	optic lobe placode formation
0.49	GO:0007299	ovarian follicle cell-cell adhesion
0.49	GO:0045434	negative regulation of female receptivity, post-mating
0.48	GO:0030720	oocyte localization involved in germarium-derived egg chamber formation
0.48	GO:0016325	oocyte microtubule cytoskeleton organization
0.48	GO:0006688	glycosphingolipid biosynthetic process
0.47	GO:0046662	regulation of oviposition
0.47	GO:0048934	peripheral nervous system neuron differentiation

0.85	GO:0019187	beta-1,4-mannosyltransferase activity
0.34	GO:0003883	CTP synthase activity
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005737	cytoplasm
0.33	GO:0005730	nucleolus
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.85

EC:2.4.1

GO:0019187

sp|O01352|DJ_DROME
Sperm-specific protein Don juan
Search

0.97	Sperm-specific protein Don juan

0.75	GO:0007291	sperm individualization
0.42	GO:0055114	oxidation-reduction process
0.38	GO:0006006	glucose metabolic process
0.37	GO:0007288	sperm axoneme assembly
0.37	GO:0030001	metal ion transport
0.35	GO:0006757	ATP generation from ADP
0.35	GO:0006090	pyruvate metabolic process
0.35	GO:0016052	carbohydrate catabolic process
0.35	GO:0019362	pyridine nucleotide metabolic process

0.39	GO:0016491	oxidoreductase activity
0.38	GO:0050661	NADP binding
0.38	GO:0051287	NAD binding
0.37	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.84	GO:0016007	mitochondrial derivative
0.70	GO:0031514	motile cilium
0.70	GO:0005930	axoneme
0.55	GO:0005634	nucleus
0.44	GO:0097223	sperm part
0.37	GO:0005747	mitochondrial respiratory chain complex I
0.33	GO:0019028	viral capsid

0.39

GO:0016491

sp|O01367|HOW_DROME
Protein held out wings
Search

0.94	Quaking protein A

0.71	GO:0006417	regulation of translation
0.37	GO:0007438	oenocyte development
0.37	GO:0007284	spermatogonial cell division
0.37	GO:0007521	muscle cell fate determination
0.36	GO:0007475	apposition of dorsal and ventral imaginal disc-derived wing surfaces
0.36	GO:0008078	mesodermal cell migration
0.36	GO:0016203	muscle attachment
0.36	GO:0007525	somatic muscle development
0.36	GO:0030718	germ-line stem cell population maintenance
0.36	GO:0008347	glial cell migration

0.79	GO:0003727	single-stranded RNA binding
0.36	GO:0003730	mRNA 3'-UTR binding
0.33	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.33	GO:0140101	catalytic activity, acting on a tRNA

0.33	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.33

EC:6.1

GO:0016875

sp|O01382|DRICE_DROME
Caspase
Search

0.63	Caspase short class

0.61	GO:0006508	proteolysis
0.54	GO:0045476	nurse cell apoptotic process
0.52	GO:0016322	neuron remodeling
0.51	GO:0097194	execution phase of apoptosis
0.49	GO:0046672	positive regulation of compound eye retinal cell programmed cell death
0.48	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
0.48	GO:0035070	salivary gland histolysis
0.47	GO:0010165	response to X-ray
0.47	GO:0032933	SREBP signaling pathway
0.46	GO:0048515	spermatid differentiation

0.75	GO:0004197	cysteine-type endopeptidase activity
0.55	GO:1990525	BIR domain binding
0.33	GO:0004813	alanine-tRNA ligase activity
0.33	GO:0000049	tRNA binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008270	zinc ion binding

0.38	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.75

EC:3.4.22

GO:0004197

sp|O01404|PHM_DROME
Peptidylglycine alpha-hydroxylating monooxygenase
Search

0.94	Peptidylglycine alpha-hydroxylating monooxygenase

0.59	GO:0006518	peptide metabolic process
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0044719	regulation of imaginal disc-derived wing size
0.48	GO:0007613	memory
0.48	GO:0009620	response to fungus
0.35	GO:0032504	multicellular organism reproduction
0.32	GO:0006979	response to oxidative stress
0.32	GO:0098869	cellular oxidant detoxification
0.32	GO:0006468	protein phosphorylation

0.84	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.72	GO:0005507	copper ion binding
0.38	GO:0004598	peptidylamidoglycolate lyase activity
0.35	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.34	GO:0008270	zinc ion binding
0.32	GO:0004601	peroxidase activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0020037	heme binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.35	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.84	EC:1.14.17	GO:0016715
0.32	KEGG:R03532	GO:0004601

sp|O01666|ATPG_DROME
ATP synthase subunit gamma, mitochondrial
Search

0.71	ATP synthase subunit gamma

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.35	GO:0006400	tRNA modification
0.33	GO:0006518	peptide metabolic process
0.33	GO:0043604	amide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0009059	macromolecule biosynthetic process

0.72	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.37	GO:0008193	tRNA guanylyltransferase activity
0.34	GO:0000287	magnesium ion binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0003723	RNA binding

0.72	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.34	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.37

EC:2.7.7

GO:0008193

sp|O01668|OPS6_DROME
Opsin Rh6
Search

LWRH

0.56	Long wavelength-sensitive visual pigment

0.79	GO:0007602	phototransduction
0.77	GO:0007601	visual perception
0.73	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.49	GO:0043052	thermotaxis
0.48	GO:0009584	detection of visible light
0.48	GO:0043153	entrainment of circadian clock by photoperiod
0.46	GO:0007605	sensory perception of sound
0.45	GO:0000122	negative regulation of transcription by RNA polymerase II

0.78	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.48	GO:0016028	rhabdomere
0.30	GO:0016020	membrane

sp|O01939|MST_DROME
Protein misato
Search

0.77

Misato

0.83	GO:0090307	mitotic spindle assembly
0.77	GO:0000070	mitotic sister chromatid segregation
0.48	GO:0007005	mitochondrion organization
0.34	GO:0008380	RNA splicing

0.36	GO:0005200	structural constituent of cytoskeleton
0.35	GO:0003924	GTPase activity
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0005737	cytoplasm
0.44	GO:0005856	cytoskeleton
0.40	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0099512	supramolecular fiber
0.35	GO:0044446	intracellular organelle part
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

sp|O02002|CASP1_DROME
Caspase-1
Search

0.63	Caspase short class

0.61	GO:0006508	proteolysis
0.54	GO:0045476	nurse cell apoptotic process
0.53	GO:0097194	execution phase of apoptosis
0.53	GO:0016322	neuron remodeling
0.49	GO:1900074	negative regulation of neuromuscular synaptic transmission
0.47	GO:0016239	positive regulation of macroautophagy
0.45	GO:0046672	positive regulation of compound eye retinal cell programmed cell death
0.45	GO:0009267	cellular response to starvation
0.45	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
0.45	GO:0035070	salivary gland histolysis

0.75	GO:0004197	cysteine-type endopeptidase activity
0.56	GO:1990525	BIR domain binding

0.40	GO:0005739	mitochondrion
0.34	GO:0005829	cytosol

0.75

EC:3.4.22

GO:0004197

sp|O02193|MOF_DROME
Males-absent on the first protein
Search

0.41	Histone acetyltransferase

0.78	GO:0016573	histone acetylation
0.59	GO:2000873	regulation of histone H4 acetylation involved in response to DNA damage stimulus
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0030330	DNA damage response, signal transduction by p53 class mediator
0.55	GO:0071479	cellular response to ionizing radiation
0.53	GO:0000077	DNA damage checkpoint
0.52	GO:0043066	negative regulation of apoptotic process
0.49	GO:0044093	positive regulation of molecular function

0.80	GO:0004402	histone acetyltransferase activity
0.51	GO:0003682	chromatin binding
0.38	GO:0140034	methylation-dependent protein binding
0.38	GO:0008134	transcription factor binding
0.38	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
0.38	GO:0042393	histone binding
0.37	GO:0019899	enzyme binding
0.36	GO:0003713	transcription coactivator activity
0.36	GO:0003729	mRNA binding
0.36	GO:0046872	metal ion binding

0.84	GO:0072487	MSL complex
0.59	GO:0016456	X chromosome located dosage compensation complex, transcription activating
0.58	GO:0044545	NSL complex
0.57	GO:0005705	polytene chromosome interband
0.50	GO:0005667	transcription factor complex
0.49	GO:0000228	nuclear chromosome
0.38	GO:0071339	MLL1 complex
0.38	GO:0000776	kinetochore
0.38	GO:0000786	nucleosome
0.37	GO:0035267	NuA4 histone acetyltransferase complex

0.80

GO:0004402

sp|O02194|PSN_DROME
Presenilin homolog
Search

0.74	Presenilin

0.82	GO:0007219	Notch signaling pathway
0.75	GO:0016485	protein processing
0.59	GO:0007220	Notch receptor processing
0.57	GO:0015677	copper ion import
0.57	GO:0007614	short-term memory
0.57	GO:0048190	wing disc dorsal/ventral pattern formation
0.56	GO:0008593	regulation of Notch signaling pathway
0.56	GO:0008306	associative learning
0.55	GO:0002027	regulation of heart rate
0.52	GO:0098609	cell-cell adhesion

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.51	GO:0042803	protein homodimerization activity

0.74	GO:0000139	Golgi membrane
0.72	GO:0005789	endoplasmic reticulum membrane
0.58	GO:0070765	gamma-secretase complex
0.54	GO:0055037	recycling endosome
0.54	GO:0016324	apical plasma membrane
0.53	GO:0005770	late endosome
0.52	GO:0005938	cell cortex
0.48	GO:0005887	integral component of plasma membrane
0.41	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0035253	ciliary rootlet

sp|O02195|EIF3I_DROME
Eukaryotic translation initiation factor 3 subunit I
Search

0.68	Eukaryotic translation initiation factor 3 subunit I

0.73	GO:0001731	formation of translation preinitiation complex
0.72	GO:0006446	regulation of translational initiation
0.42	GO:0002040	sprouting angiogenesis
0.42	GO:0001889	liver development
0.32	GO:0016310	phosphorylation

0.73	GO:0003743	translation initiation factor activity
0.33	GO:0016301	kinase activity
0.33	GO:0008080	N-acetyltransferase activity

0.78	GO:0005852	eukaryotic translation initiation factor 3 complex
0.72	GO:0016282	eukaryotic 43S preinitiation complex
0.72	GO:0033290	eukaryotic 48S preinitiation complex
0.30	GO:0016020	membrane

0.33

GO:0008080

sp|O02372|OB76A_DROME
General odorant-binding protein lush
Search

0.57	General odorant-binding protein lush

0.74	GO:0007619	courtship behavior
0.73	GO:0042048	olfactory behavior
0.69	GO:0019236	response to pheromone
0.64	GO:0007608	sensory perception of smell
0.50	GO:0045471	response to ethanol

0.82	GO:0035275	dibutyl phthalate binding
0.81	GO:0035274	diphenyl phthalate binding
0.80	GO:0005549	odorant binding
0.53	GO:0035276	ethanol binding

0.57

GO:0005576

extracellular region

sp|O02373|UGDH_DROME
UDP-glucose 6-dehydrogenase
Search

0.44	UDP-glucose 6-dehydrogenase

0.53	GO:0007369	gastrulation
0.53	GO:0055114	oxidation-reduction process
0.47	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
0.46	GO:0007427	epithelial cell migration, open tracheal system
0.46	GO:0008078	mesodermal cell migration
0.46	GO:0007367	segment polarity determination
0.46	GO:0006024	glycosaminoglycan biosynthetic process
0.45	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process
0.45	GO:0030204	chondroitin sulfate metabolic process
0.45	GO:0048332	mesoderm morphogenesis

0.76	GO:0003979	UDP-glucose 6-dehydrogenase activity
0.68	GO:0051287	NAD binding
0.33	GO:0009055	electron transfer activity
0.32	GO:0003676	nucleic acid binding

0.44	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol
0.35	GO:0070062	extracellular exosome
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.76	EC:1.1.1.22	GO:0003979
0.76	KEGG:R00286	GO:0003979

sp|O02649|CH60_DROME
60 kDa heat shock protein, mitochondrial
Search

0.62	Heat shock protein, mitochondrial

0.76	GO:0042026	protein refolding
0.46	GO:0007301	female germline ring canal formation
0.44	GO:0007424	open tracheal system development
0.44	GO:0030707	ovarian follicle cell development
0.43	GO:0007283	spermatogenesis
0.42	GO:0007005	mitochondrion organization
0.41	GO:0034605	cellular response to heat
0.39	GO:0006458	'de novo' protein folding
0.38	GO:1990542	mitochondrial transmembrane transport
0.38	GO:0044743	protein transmembrane import into intracellular organelle

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0044183	protein binding involved in protein folding
0.37	GO:0051082	unfolded protein binding
0.34	GO:0036402	proteasome-activating ATPase activity
0.34	GO:0015299	solute:proton antiporter activity

0.49	GO:0005737	cytoplasm
0.37	GO:0019866	organelle inner membrane
0.37	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0031974	membrane-enclosed lumen
0.30	GO:0016021	integral component of membrane

sp|O15943|CADN_DROME
Neural-cadherin
Search

LOC108100355

0.93	Neural-cadherin

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.37	GO:0045463	R8 cell development
0.36	GO:0001736	establishment of planar polarity
0.36	GO:0045467	R7 cell development
0.36	GO:0044331	cell-cell adhesion mediated by cadherin
0.36	GO:0007412	axon target recognition
0.36	GO:0050774	negative regulation of dendrite morphogenesis
0.36	GO:1902284	neuron projection extension involved in neuron projection guidance
0.36	GO:0048841	regulation of axon extension involved in axon guidance
0.36	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

0.70	GO:0005509	calcium ion binding
0.36	GO:0050839	cell adhesion molecule binding
0.35	GO:0008013	beta-catenin binding
0.35	GO:0042803	protein homodimerization activity
0.34	GO:0004872	receptor activity
0.33	GO:0032403	protein complex binding

0.56	GO:0005886	plasma membrane
0.35	GO:0030054	cell junction
0.35	GO:0120025	plasma membrane bounded cell projection
0.35	GO:0036477	somatodendritic compartment
0.34	GO:0044463	cell projection part
0.34	GO:0031254	cell trailing edge
0.33	GO:0045178	basal part of cell
0.30	GO:0016021	integral component of membrane

sp|O15945|ARNT_DROME
Aryl hydrocarbon receptor nuclear translocator homolog
Search

0.79	Aryl hydrocarbon receptor nuclear translocator

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0006351	transcription, DNA-templated
0.52	GO:0045676	regulation of R7 cell differentiation
0.50	GO:0008347	glial cell migration
0.49	GO:0071456	cellular response to hypoxia
0.49	GO:0032869	cellular response to insulin stimulus
0.49	GO:0060173	limb development
0.48	GO:0048477	oogenesis

0.66	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.49	GO:0017022	myosin binding
0.48	GO:0003677	DNA binding
0.34	GO:0003989	acetyl-CoA carboxylase activity

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.34

EC:6.4.1.2

GO:0003989

tr|O15971|O15971_DROME
LD39986p
Search

0.58	ADP ribosylation factor

0.53	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane
0.51	GO:0071786	endoplasmic reticulum tubular network organization
0.50	GO:0032869	cellular response to insulin stimulus
0.48	GO:0072659	protein localization to plasma membrane
0.48	GO:0016197	endosomal transport
0.47	GO:0016192	vesicle-mediated transport
0.47	GO:0098609	cell-cell adhesion
0.47	GO:0110010	basolateral protein secretion
0.47	GO:0019882	antigen processing and presentation
0.46	GO:0061864	basement membrane constituent secretion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0098641	cadherin binding involved in cell-cell adhesion
0.51	GO:0031489	myosin V binding

0.55	GO:0032593	insulin-responsive compartment
0.50	GO:0071782	endoplasmic reticulum tubular network
0.50	GO:0055037	recycling endosome
0.49	GO:0005913	cell-cell adherens junction
0.49	GO:0070382	exocytic vesicle
0.47	GO:0005929	cilium
0.47	GO:0005794	Golgi apparatus
0.46	GO:0005789	endoplasmic reticulum membrane
0.45	GO:0031254	cell trailing edge
0.44	GO:0045178	basal part of cell

sp|O16011|MBL_DROME
Protein muscleblind
Search

MBL

0.75	Protein muscleblind

0.36	GO:0045924	regulation of female receptivity
0.36	GO:0042052	rhabdomere development
0.36	GO:0007525	somatic muscle development
0.36	GO:0046716	muscle cell cellular homeostasis
0.36	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.36	GO:0007422	peripheral nervous system development
0.35	GO:0007517	muscle organ development
0.35	GO:0007601	visual perception
0.35	GO:0006915	apoptotic process
0.33	GO:0050896	response to stimulus

0.54	GO:0046872	metal ion binding
0.33	GO:0003677	DNA binding

0.37	GO:0031673	H zone
0.36	GO:0030018	Z disc
0.35	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|O16043|O16043_DROME
Anon1A4
Search

0.94	Decondensation factor 31

0.76	GO:0006334	nucleosome assembly
0.37	GO:0043666	regulation of phosphoprotein phosphatase activity
0.35	GO:0046907	intracellular transport
0.34	GO:0006508	proteolysis

0.77	GO:0042393	histone binding
0.37	GO:0019888	protein phosphatase regulator activity
0.36	GO:0004198	calcium-dependent cysteine-type endopeptidase activity

0.81	GO:0005700	polytene chromosome
0.70	GO:0000785	chromatin
0.59	GO:0005634	nucleus
0.37	GO:0030289	protein phosphatase 4 complex
0.36	GO:0005856	cytoskeleton
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|O16102|CHD3_DROME
Chromodomain-helicase-DNA-binding protein 3
Search

0.53	Chromodomain-helicase-DNA-binding protein 3

0.64	GO:0006325	chromatin organization
0.63	GO:0007098	centrosome cycle
0.62	GO:0007051	spindle organization
0.54	GO:0071824	protein-DNA complex subunit organization
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression
0.33	GO:0016567	protein ubiquitination

0.62	GO:0070615	nucleosome-dependent ATPase activity
0.58	GO:0031491	nucleosome binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0004386	helicase activity
0.52	GO:0046872	metal ion binding
0.49	GO:0003677	DNA binding
0.33	GO:0004842	ubiquitin-protein transferase activity

0.66	GO:0090545	CHD-type complex
0.64	GO:0090568	nuclear transcriptional repressor complex
0.63	GO:0000118	histone deacetylase complex
0.59	GO:0035327	transcriptionally active chromatin
0.33	GO:0005829	cytosol
0.32	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004842

tr|O16117|O16117_DROME
Shaven, isoform A
Search

0.97	paired box protein Pax-2-A isoform X5

0.70	GO:0007275	multicellular organism development
0.65	GO:0042682	regulation of compound eye cone cell fate specification
0.63	GO:0061074	regulation of neural retina development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0051960	regulation of nervous system development
0.56	GO:0060284	regulation of cell development
0.54	GO:1902680	positive regulation of RNA biosynthetic process

0.60	GO:0001158	enhancer sequence-specific DNA binding
0.60	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.35	GO:0016301	kinase activity
0.34	GO:0000987	proximal promoter sequence-specific DNA binding
0.33	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.34	GO:0034451	centriolar satellite
0.33	GO:0005794	Golgi apparatus
0.33	GO:0043233	organelle lumen
0.30	GO:0016020	membrane

sp|O16129|SYFM_DROME
Probable phenylalanine--tRNA ligase, mitochondrial
Search

0.63	Phenylalanyl-tRNA synthetase mitochondrial

0.77	GO:0006432	phenylalanyl-tRNA aminoacylation
0.34	GO:0008033	tRNA processing
0.34	GO:0070127	tRNA aminoacylation for mitochondrial protein translation

0.76	GO:0004826	phenylalanine-tRNA ligase activity
0.69	GO:0000049	tRNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005737	cytoplasm
0.38	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0044446	intracellular organelle part
0.35	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.76

EC:6.1.1.20

GO:0004826

sp|O16130|RL39_DROME
60S ribosomal protein L39
Search

RPL39

0.80	Ribosomal protein rpl39

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0006886	intracellular protein transport
0.34	GO:0016192	vesicle-mediated transport
0.34	GO:0043413	macromolecule glycosylation
0.34	GO:0009100	glycoprotein metabolic process
0.33	GO:1901137	carbohydrate derivative biosynthetic process
0.33	GO:0036211	protein modification process

0.64	GO:0003735	structural constituent of ribosome
0.35	GO:0003723	RNA binding
0.33	GO:0016757	transferase activity, transferring glycosyl groups

0.61	GO:0005840	ribosome
0.43	GO:0044445	cytosolic part
0.39	GO:0044446	intracellular organelle part
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016757

tr|O16158|O16158_DROME
Calcium-binding protein
Search

0.44	Juvenile hormone diol kinase

0.38

GO:0016310

phosphorylation

0.70	GO:0005509	calcium ion binding
0.46	GO:0003924	GTPase activity
0.39	GO:0016301	kinase activity

tr|O16528|O16528_DROME
Bearded
Search

BRD

0.97

Bearded

0.84	GO:0001708	cell fate specification
0.82	GO:0007219	Notch signaling pathway
0.79	GO:0007423	sensory organ development
0.72	GO:0060582	cell fate determination involved in pattern specification
0.71	GO:0010160	formation of animal organ boundary

0.53

GO:0005515

protein binding

sp|O16797|RL3_DROME
60S ribosomal protein L3
Search

RPL3

0.61	Ribosomal protein L3

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.36	GO:0000027	ribosomal large subunit assembly

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.36	GO:0044445	cytosolic part
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|O16810|ORC1_DROME
Origin recognition complex subunit 1
Search

ORC1

0.63	Origin recognition complex subunit 1

0.54	GO:0006277	DNA amplification
0.52	GO:0006270	DNA replication initiation
0.50	GO:0008283	cell proliferation
0.40	GO:0051301	cell division
0.38	GO:0042023	DNA endoreduplication
0.34	GO:0070318	positive regulation of G0 to G1 transition
0.34	GO:0001878	response to yeast
0.34	GO:1903047	mitotic cell cycle process
0.34	GO:0048661	positive regulation of smooth muscle cell proliferation
0.34	GO:0040014	regulation of multicellular organism growth

0.71	GO:0003682	chromatin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0003677	DNA binding
0.33	GO:0005515	protein binding
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0004497	monooxygenase activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0020037	heme binding

0.55	GO:0005664	nuclear origin of replication recognition complex
0.43	GO:0000784	nuclear chromosome, telomeric region
0.40	GO:0005730	nucleolus
0.39	GO:0005829	cytosol
0.36	GO:0005886	plasma membrane
0.34	GO:0005654	nucleoplasm
0.33	GO:0036387	pre-replicative complex
0.33	GO:0043596	nuclear replication fork
0.33	GO:0000790	nuclear chromatin
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016705

sp|O16829|CECC_DROME
Cecropin-C
Search

0.96	Sarcotoxin-G

0.85	GO:0019731	antibacterial humoral response
0.77	GO:0045087	innate immune response
0.52	GO:0050830	defense response to Gram-positive bacterium
0.52	GO:0050829	defense response to Gram-negative bacterium
0.37	GO:0019835	cytolysis

0.66	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|O16844|COS_DROME
Kinesin-like protein costa
Search

COS

0.89	Kinesin-like protein costa

0.74	GO:0007018	microtubule-based movement
0.69	GO:0007228	positive regulation of hh target transcription factor activity
0.64	GO:0007476	imaginal disc-derived wing morphogenesis
0.64	GO:0043433	negative regulation of DNA binding transcription factor activity
0.62	GO:0031503	protein complex localization
0.62	GO:0030705	cytoskeleton-dependent intracellular transport
0.61	GO:0031647	regulation of protein stability
0.61	GO:0044782	cilium organization
0.58	GO:0042981	regulation of apoptotic process
0.55	GO:0006886	intracellular protein transport

0.74	GO:0003777	microtubule motor activity
0.73	GO:0008017	microtubule binding
0.70	GO:0005119	smoothened binding
0.60	GO:0019901	protein kinase binding
0.58	GO:0042803	protein homodimerization activity
0.57	GO:0008134	transcription factor binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0042623	ATPase activity, coupled

0.69	GO:0035301	Hedgehog signaling complex
0.59	GO:0005875	microtubule associated complex
0.59	GO:0005929	cilium
0.59	GO:0012506	vesicle membrane
0.46	GO:0005886	plasma membrane
0.42	GO:0005874	microtubule
0.42	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.35	EC:3.1.4.11	GO:0004435
0.35	KEGG:R03435	GO:0004435

sp|O16867|TAP_DROME
Basic helix-loop-helix neural transcription factor TAP
Search

0.86	Basic helix-loop-helix neural transcription factor TAP

0.74	GO:0022008	neurogenesis
0.56	GO:0048513	animal organ development
0.56	GO:0051960	regulation of nervous system development
0.56	GO:0060284	regulation of cell development
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.53	GO:0051241	negative regulation of multicellular organismal process
0.52	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.52	GO:0050922	negative regulation of chemotaxis

0.68	GO:0046983	protein dimerization activity
0.49	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0003682	chromatin binding
0.47	GO:0000989	transcription factor activity, transcription factor binding
0.44	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.43	GO:0001047	core promoter binding
0.42	GO:0042802	identical protein binding
0.36	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0008009	chemokine activity

0.45	GO:0043204	perikaryon
0.45	GO:0005634	nucleus
0.32	GO:0005829	cytosol
0.32	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|O16868|FUZZY_DROME
Protein fuzzy
Search

0.91	Fuzzy, isoform B

0.78	GO:0007163	establishment or maintenance of cell polarity
0.49	GO:0001737	establishment of imaginal disc-derived wing hair orientation

0.46	GO:0005856	cytoskeleton
0.38	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|O17432|O17432_DROME
Cyclin-dependent kinase 9
Search

0.68	Cell division protein kinase

0.63	GO:0006468	protein phosphorylation
0.47	GO:0006368	transcription elongation from RNA polymerase II promoter
0.47	GO:0002230	positive regulation of defense response to virus by host
0.46	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0051726	regulation of cell cycle
0.45	GO:0061026	cardiac muscle tissue regeneration
0.44	GO:0060043	regulation of cardiac muscle cell proliferation
0.43	GO:0009408	response to heat
0.40	GO:0051301	cell division
0.37	GO:1903839	positive regulation of mRNA 3'-UTR binding

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.49	GO:0097472	cyclin-dependent protein kinase activity
0.41	GO:0030332	cyclin binding
0.40	GO:0044212	transcription regulatory region DNA binding
0.39	GO:0008134	transcription factor binding
0.36	GO:0097322	7SK snRNA binding

0.47	GO:0008023	transcription elongation factor complex
0.47	GO:0005703	polytene chromosome puff
0.42	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex
0.41	GO:0032806	carboxy-terminal domain protein kinase complex
0.36	GO:0016605	PML body
0.35	GO:0036464	cytoplasmic ribonucleoprotein granule
0.30	GO:0016020	membrane

0.68

GO:0004674

sp|O17444|VACHT_DROME
Vesicular acetylcholine transporter
Search

0.42	Vesicular acetylcholine transporter

0.68	GO:0006855	drug transmembrane transport
0.45	GO:1901374	acetate ester transport
0.41	GO:0072488	ammonium transmembrane transport
0.41	GO:0015695	organic cation transport
0.41	GO:0006836	neurotransmitter transport
0.36	GO:0043051	regulation of pharyngeal pumping
0.36	GO:0007271	synaptic transmission, cholinergic
0.36	GO:0046928	regulation of neurotransmitter secretion
0.36	GO:0002119	nematode larval development
0.35	GO:0006937	regulation of muscle contraction

0.67	GO:0015238	drug transmembrane transporter activity
0.45	GO:1901375	acetate ester transmembrane transporter activity
0.44	GO:0042166	acetylcholine binding
0.42	GO:0015101	organic cation transmembrane transporter activity
0.41	GO:0005326	neurotransmitter transporter activity
0.41	GO:0008519	ammonium transmembrane transporter activity
0.40	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0008237	metallopeptidase activity
0.33	GO:0008270	zinc ion binding

0.44	GO:0030121	AP-1 adaptor complex
0.43	GO:0030122	AP-2 adaptor complex
0.39	GO:0005887	integral component of plasma membrane
0.36	GO:0060076	excitatory synapse
0.35	GO:0008021	synaptic vesicle
0.35	GO:0043005	neuron projection
0.34	GO:0099501	exocytic vesicle membrane
0.33	GO:0031301	integral component of organelle membrane
0.33	GO:0030054	cell junction

0.40

EC:2.3

GO:0016746

sp|O17445|RL15_DROME
60S ribosomal protein L15
Search

0.66	Ribosomal protein L15

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process

0.64	GO:0003735	structural constituent of ribosome
0.35	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.37	GO:0044445	cytosolic part
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|O17452|O17452_DROME
LD20793p
Search

0.77	Cuticular protein analogous to peritrophins 3-D

0.78	GO:0006030	chitin metabolic process
0.37	GO:0032504	multicellular organism reproduction

0.77

GO:0008061

chitin binding

0.66	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|O17468|HIRA_DROME
Protein HIRA homolog
Search

0.72	GO:0006325	chromatin organization
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0043412	macromolecule modification
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:0010468	regulation of gene expression
0.54	GO:0035039	male pronucleus assembly
0.54	GO:0065004	protein-DNA complex assembly
0.53	GO:0006323	DNA packaging
0.43	GO:1902275	regulation of chromatin organization

0.51	GO:0003682	chromatin binding
0.43	GO:0003714	transcription corepressor activity
0.41	GO:0044877	macromolecular complex binding
0.34	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.45	GO:0000785	chromatin
0.43	GO:0031974	membrane-enclosed lumen
0.39	GO:0043234	protein complex
0.35	GO:0070062	extracellular exosome

tr|O18332|O18332_DROME
FI01544p
Search

0.70	Rab protein 1

0.49	GO:1905345	protein localization to cleavage furrow
0.47	GO:0007112	male meiosis cytokinesis
0.47	GO:0050775	positive regulation of dendrite morphogenesis
0.47	GO:0008089	anterograde axonal transport
0.46	GO:0032024	positive regulation of insulin secretion
0.46	GO:0034067	protein localization to Golgi apparatus
0.45	GO:0007030	Golgi organization
0.45	GO:0000281	mitotic cytokinesis
0.45	GO:0033500	carbohydrate homeostasis
0.44	GO:0030334	regulation of cell migration

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.46	GO:1904115	axon cytoplasm
0.46	GO:0032154	cleavage furrow
0.44	GO:0005794	Golgi apparatus
0.39	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0098588	bounding membrane of organelle
0.34	GO:0043025	neuronal cell body
0.34	GO:0000145	exocyst
0.34	GO:0031982	vesicle

tr|O18333|O18333_DROME
GH01619p
Search

0.62	ADP ribosylation factor

0.45	GO:0007030	Golgi organization
0.39	GO:0016192	vesicle-mediated transport
0.37	GO:0032482	Rab protein signal transduction
0.37	GO:0015031	protein transport
0.35	GO:0006470	protein dephosphorylation
0.34	GO:0043687	post-translational protein modification
0.34	GO:0006106	fumarate metabolic process
0.34	GO:0000469	cleavage involved in rRNA processing
0.33	GO:0042274	ribosomal small subunit biogenesis
0.33	GO:0046907	intracellular transport

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0004767	sphingomyelin phosphodiesterase activity
0.35	GO:0004721	phosphoprotein phosphatase activity
0.35	GO:0005515	protein binding
0.34	GO:0004333	fumarate hydratase activity
0.33	GO:0004521	endoribonuclease activity

0.47	GO:0005794	Golgi apparatus
0.41	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.39	GO:0042470	melanosome
0.38	GO:0031984	organelle subcompartment
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0044432	endoplasmic reticulum part
0.36	GO:0043025	neuronal cell body
0.34	GO:0005634	nucleus
0.34	GO:0005765	lysosomal membrane
0.34	GO:0070062	extracellular exosome

0.36	EC:3.1.4.12	GO:0004767
0.36	KEGG:R02541	GO:0004767

sp|O18334|RAB6_DROME
Ras-related protein Rab6
Search

RAB6A

0.40	ADP ribosylation factor

0.46	GO:0045467	R7 cell development
0.46	GO:0008103	oocyte microtubule cytoskeleton polarization
0.46	GO:0045451	pole plasm oskar mRNA localization
0.45	GO:0007293	germarium-derived egg chamber formation
0.44	GO:0016192	vesicle-mediated transport
0.44	GO:0050832	defense response to fungus
0.44	GO:0016482	cytosolic transport
0.43	GO:0007411	axon guidance
0.43	GO:0016197	endosomal transport
0.43	GO:0060078	regulation of postsynaptic membrane potential

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.38	GO:0031489	myosin V binding
0.36	GO:0019904	protein domain specific binding
0.34	GO:0051117	ATPase binding
0.34	GO:0001671	ATPase activator activity
0.34	GO:0003779	actin binding
0.33	GO:0004252	serine-type endopeptidase activity

0.47	GO:0005794	Golgi apparatus
0.42	GO:0031410	cytoplasmic vesicle
0.41	GO:0005829	cytosol
0.38	GO:0031984	organelle subcompartment
0.37	GO:0098588	bounding membrane of organelle
0.35	GO:0070062	extracellular exosome
0.35	GO:0043204	perikaryon
0.34	GO:0045202	synapse
0.34	GO:0030054	cell junction
0.34	GO:0012506	vesicle membrane

0.33

GO:0004252

tr|O18335|O18335_DROME
Drab11
Search

0.57	ADP ribosylation factor

0.46	GO:0046664	dorsal closure, amnioserosa morphology change
0.46	GO:1990182	exosomal secretion
0.46	GO:0032482	Rab protein signal transduction
0.46	GO:0048210	Golgi vesicle fusion to target membrane
0.46	GO:0030723	ovarian fusome organization
0.46	GO:0007394	dorsal closure, elongation of leading edge cells
0.46	GO:0008103	oocyte microtubule cytoskeleton polarization
0.46	GO:0016360	sensory organ precursor cell fate determination
0.46	GO:0048137	spermatocyte division
0.46	GO:0007317	regulation of pole plasm oskar mRNA localization

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.46	GO:0032794	GTPase activating protein binding
0.42	GO:0032403	protein complex binding
0.41	GO:0031489	myosin V binding
0.39	GO:0019003	GDP binding
0.38	GO:0045296	cadherin binding
0.34	GO:0008017	microtubule binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0030554	adenyl nucleotide binding

0.48	GO:0055037	recycling endosome
0.47	GO:0070732	spindle envelope
0.46	GO:0060187	cell pole
0.45	GO:0045169	fusome
0.45	GO:0097610	cell surface furrow
0.44	GO:0043195	terminal bouton
0.44	GO:0005776	autophagosome
0.44	GO:0032155	cell division site part
0.43	GO:0030140	trans-Golgi network transport vesicle
0.43	GO:0048471	perinuclear region of cytoplasm

0.33

GO:0004674

tr|O18338|O18338_DROME
LD44762p
Search

RAB8A

0.74	Rab protein 8

0.48	GO:0061865	polarized secretion of basement membrane proteins in epithelium
0.46	GO:0008582	regulation of synaptic growth at neuromuscular junction
0.45	GO:0006904	vesicle docking involved in exocytosis
0.44	GO:0048210	Golgi vesicle fusion to target membrane
0.43	GO:0072659	protein localization to plasma membrane
0.43	GO:0017157	regulation of exocytosis
0.42	GO:0060271	cilium assembly
0.41	GO:0010506	regulation of autophagy
0.40	GO:0009306	protein secretion
0.39	GO:0007275	multicellular organism development

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.44	GO:0019003	GDP binding
0.44	GO:0031489	myosin V binding
0.38	GO:0017137	Rab GTPase binding
0.35	GO:0019901	protein kinase binding
0.33	GO:0005102	receptor binding

0.49	GO:0055037	recycling endosome
0.47	GO:0045202	synapse
0.47	GO:0097458	neuron part
0.45	GO:0044297	cell body
0.44	GO:0030133	transport vesicle
0.43	GO:0045335	phagocytic vesicle
0.43	GO:0030667	secretory granule membrane
0.43	GO:0005794	Golgi apparatus
0.42	GO:0097546	ciliary base
0.42	GO:0097730	non-motile cilium

tr|O18339|O18339_DROME
RE48347p
Search

0.77	Putative rab subfamily protein of small gtpase

0.44	GO:0035526	retrograde transport, plasma membrane to Golgi
0.43	GO:0090382	phagosome maturation
0.42	GO:0007030	Golgi organization
0.41	GO:0071346	cellular response to interferon-gamma
0.40	GO:1901998	toxin transport
0.39	GO:0019068	virion assembly
0.36	GO:0032482	Rab protein signal transduction
0.35	GO:0051382	kinetochore assembly
0.35	GO:0043547	positive regulation of GTPase activity
0.34	GO:0070507	regulation of microtubule cytoskeleton organization

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0004767	sphingomyelin phosphodiesterase activity
0.35	GO:0005515	protein binding
0.35	GO:0005096	GTPase activator activity
0.33	GO:0000049	tRNA binding

0.47	GO:0005794	Golgi apparatus
0.46	GO:0043025	neuronal cell body
0.44	GO:0045202	synapse
0.42	GO:0031410	cytoplasmic vesicle
0.34	GO:0070062	extracellular exosome
0.34	GO:0005874	microtubule
0.33	GO:0012506	vesicle membrane
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0031984	organelle subcompartment

0.36	EC:3.1.4.12	GO:0004767
0.36	KEGG:R02541	GO:0004767

sp|O18373|SPS1_DROME
Selenide, water dikinase
Search

0.46	Selenophosphate synthetase

0.76	GO:0016260	selenocysteine biosynthetic process
0.57	GO:0016310	phosphorylation
0.38	GO:2000378	negative regulation of reactive oxygen species metabolic process
0.38	GO:0007444	imaginal disc development
0.37	GO:0008283	cell proliferation
0.37	GO:0008284	positive regulation of cell proliferation
0.37	GO:0007005	mitochondrion organization
0.36	GO:0006541	glutamine metabolic process
0.35	GO:0046041	ITP metabolic process
0.34	GO:0006172	ADP biosynthetic process

0.80	GO:0004756	selenide, water dikinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0042802	identical protein binding
0.35	GO:0046899	nucleoside triphosphate adenylate kinase activity
0.34	GO:0004017	adenylate kinase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.34	GO:0005759	mitochondrial matrix
0.30	GO:0016020	membrane

0.80	EC:2.7.9.3	GO:0004756
0.80	KEGG:R03595	GO:0004756

sp|O18381|PAX6_DROME
Paired box protein Pax-6
Search

0.70	Paired box protein Pax-6

0.69	GO:0007275	multicellular organism development
0.65	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.64	GO:0007628	adult walking behavior
0.63	GO:0040018	positive regulation of multicellular organism growth
0.62	GO:0001708	cell fate specification
0.61	GO:0030307	positive regulation of cell growth
0.60	GO:0042593	glucose homeostasis
0.59	GO:0060322	head development
0.59	GO:0008284	positive regulation of cell proliferation
0.58	GO:0016477	cell migration

0.62	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.62	GO:0043565	sequence-specific DNA binding
0.58	GO:0001012	RNA polymerase II regulatory region DNA binding
0.55	GO:0003690	double-stranded DNA binding
0.37	GO:0005515	protein binding
0.34	GO:0005096	GTPase activator activity
0.33	GO:0004930	G-protein coupled receptor activity

0.61	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|O18388|IMB_DROME
Importin subunit beta
Search

0.55	Importin subunit beta

0.68	GO:0006886	intracellular protein transport
0.50	GO:0006607	NLS-bearing protein import into nucleus
0.44	GO:0006610	ribosomal protein import into nucleus
0.40	GO:0007079	mitotic chromosome movement towards spindle pole
0.40	GO:0031291	Ran protein signal transduction
0.40	GO:0030953	astral microtubule organization
0.39	GO:0007080	mitotic metaphase plate congression
0.39	GO:0090307	mitotic spindle assembly
0.39	GO:0040001	establishment of mitotic spindle localization
0.35	GO:0007304	chorion-containing eggshell formation

0.79	GO:0008536	Ran GTPase binding
0.41	GO:0008139	nuclear localization sequence binding
0.40	GO:0008565	protein transporter activity
0.39	GO:0051879	Hsp90 protein binding
0.38	GO:0019904	protein domain specific binding
0.34	GO:0046982	protein heterodimerization activity
0.32	GO:0003677	DNA binding
0.31	GO:0046873	metal ion transmembrane transporter activity

0.47	GO:0043186	P granule
0.47	GO:0005635	nuclear envelope
0.40	GO:0034399	nuclear periphery
0.39	GO:0071782	endoplasmic reticulum tubular network
0.37	GO:0005654	nucleoplasm
0.37	GO:0031090	organelle membrane
0.36	GO:0005829	cytosol
0.36	GO:0043234	protein complex
0.34	GO:0000786	nucleosome
0.30	GO:0016021	integral component of membrane

sp|O18391|KRAK_DROME
Probable serine hydrolase
Search

0.29	Valacyclovir hydrolase

0.57	GO:0007586	digestion
0.49	GO:0009636	response to toxic substance
0.36	GO:0007275	multicellular organism development
0.34	GO:1901071	glucosamine-containing compound metabolic process
0.34	GO:0009234	menaquinone biosynthetic process
0.33	GO:0006022	aminoglycan metabolic process
0.33	GO:0005975	carbohydrate metabolic process
0.32	GO:0017144	drug metabolic process

0.46	GO:0016787	hydrolase activity
0.36	GO:0003723	RNA binding
0.34	GO:0070205	2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity
0.34	GO:0005198	structural molecule activity
0.34	GO:0016740	transferase activity
0.34	GO:0008061	chitin binding
0.32	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses

0.36	GO:0005882	intermediate filament
0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.46	EC:3	GO:0016787
0.34	KEGG:R08166	GO:0070205

tr|O18399|O18399_DROME
EG:152A3.5 protein (Fbgn0003116;pn protein)
Search

0.68	Prune exopolyphosphatase 1

0.61	GO:0019889	pteridine metabolic process
0.60	GO:0090297	positive regulation of mitochondrial DNA replication
0.60	GO:0048072	compound eye pigmentation
0.59	GO:0043951	negative regulation of cAMP-mediated signaling
0.57	GO:0006198	cAMP catabolic process
0.56	GO:0001745	compound eye morphogenesis
0.47	GO:0031113	regulation of microtubule polymerization
0.45	GO:0050767	regulation of neurogenesis
0.42	GO:0016311	dephosphorylation
0.36	GO:0006468	protein phosphorylation

0.58	GO:0016462	pyrophosphatase activity
0.53	GO:0004112	cyclic-nucleotide phosphodiesterase activity
0.43	GO:0015631	tubulin binding
0.42	GO:0016791	phosphatase activity
0.36	GO:0004672	protein kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046872	metal ion binding

0.52	GO:0005759	mitochondrial matrix
0.42	GO:0005829	cytosol
0.35	GO:0005925	focal adhesion
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.58

EC:3.6.1

GO:0016462

sp|O18400|PITX_DROME
Pituitary homeobox homolog Ptx1
Search

0.96	Pituitary homeobox homolog Ptx1

0.68	GO:0007275	multicellular organism development
0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.45	GO:2000288	positive regulation of myoblast proliferation
0.44	GO:0003228	atrial cardiac muscle tissue development
0.44	GO:0048857	neural nucleus development
0.44	GO:0051145	smooth muscle cell differentiation
0.43	GO:0007520	myoblast fusion
0.43	GO:0043388	positive regulation of DNA binding

0.62	GO:0043565	sequence-specific DNA binding
0.49	GO:0003700	DNA binding transcription factor activity
0.44	GO:0001105	RNA polymerase II transcription coactivator activity
0.44	GO:0001102	RNA polymerase II activating transcription factor binding
0.43	GO:0031490	chromatin DNA binding
0.41	GO:0044212	transcription regulatory region DNA binding
0.40	GO:0003690	double-stranded DNA binding
0.34	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.33	GO:0051219	phosphoprotein binding
0.33	GO:0042803	protein homodimerization activity

0.61	GO:0005634	nucleus
0.42	GO:0005667	transcription factor complex
0.35	GO:0005737	cytoplasm
0.32	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part

sp|O18404|HCD2_DROME
3-hydroxyacyl-CoA dehydrogenase type-2
Search

0.34	Short-chain alcohol dehydrogenase/3-hydroxyacyl-CoA dehydrogenase

0.53	GO:0055114	oxidation-reduction process
0.48	GO:0008205	ecdysone metabolic process
0.47	GO:0090646	mitochondrial tRNA processing
0.47	GO:0008209	androgen metabolic process
0.47	GO:0008210	estrogen metabolic process
0.42	GO:0035383	thioester metabolic process
0.41	GO:0006631	fatty acid metabolic process
0.40	GO:0006732	coenzyme metabolic process
0.37	GO:0006793	phosphorus metabolic process
0.35	GO:0099116	tRNA 5'-end processing

0.54	GO:0016491	oxidoreductase activity
0.34	GO:0004526	ribonuclease P activity
0.33	GO:0004312	fatty acid synthase activity
0.33	GO:0000049	tRNA binding

0.49	GO:0030678	mitochondrial ribonuclease P complex
0.34	GO:0005829	cytosol

0.54

GO:0016491

sp|O18405|SURF4_DROME
Surfeit locus protein 4 homolog
Search

0.92

Surfeit 4

0.33

GO:0007186

G-protein coupled receptor signaling pathway

0.33	GO:0003924	GTPase activity
0.33	GO:0005525	GTP binding
0.33	GO:0004930	G-protein coupled receptor activity

0.47	GO:0045169	fusome
0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|O18408|AMYR_DROME
Alpha-amylase-related protein
Search

AMYREL

0.42	Alpha-amylase

0.60

GO:0005975

carbohydrate metabolic process

0.77	GO:0103025	alpha-amylase activity (releasing maltohexaose)
0.76	GO:0004556	alpha-amylase activity
0.53	GO:0043169	cation binding

0.44

GO:0005576

extracellular region

0.76

GO:0004556

sp|O18412|FZO_DROME
Transmembrane GTPase fzo
Search

MFN2

0.65	Transmembrane GTPase Marf

0.85	GO:0008053	mitochondrial fusion
0.63	GO:0048662	negative regulation of smooth muscle cell proliferation
0.50	GO:0051646	mitochondrion localization
0.50	GO:0007287	Nebenkern assembly
0.48	GO:0030382	sperm mitochondrion organization
0.44	GO:0007275	multicellular organism development
0.44	GO:1905461	positive regulation of vascular associated smooth muscle cell apoptotic process
0.44	GO:0061734	parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
0.44	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.43	GO:0034497	protein localization to phagophore assembly site

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.41	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0003676	nucleic acid binding
0.31	GO:0003700	DNA binding transcription factor activity

0.77	GO:0005741	mitochondrial outer membrane
0.44	GO:0098573	intrinsic component of mitochondrial membrane
0.42	GO:1904115	axon cytoplasm
0.39	GO:0015630	microtubule cytoskeleton
0.34	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|O18413|PRS8_DROME
26S protease regulatory subunit 8
Search

0.67	26S protease regulatory subunit

0.80	GO:1901800	positive regulation of proteasomal protein catabolic process
0.70	GO:0030163	protein catabolic process
0.52	GO:0006508	proteolysis
0.44	GO:0043632	modification-dependent macromolecule catabolic process
0.42	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.40	GO:0034976	response to endoplasmic reticulum stress
0.40	GO:0010243	response to organonitrogen compound
0.39	GO:0044267	cellular protein metabolic process
0.39	GO:0006378	mRNA polyadenylation
0.38	GO:0045892	negative regulation of transcription, DNA-templated

0.82	GO:0036402	proteasome-activating ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0008233	peptidase activity
0.44	GO:0031531	thyrotropin-releasing hormone receptor binding
0.42	GO:0008134	transcription factor binding
0.38	GO:0003729	mRNA binding
0.37	GO:0043021	ribonucleoprotein complex binding
0.34	GO:0008568	microtubule-severing ATPase activity

0.52	GO:1905369	endopeptidase complex
0.49	GO:0005737	cytoplasm
0.46	GO:0043234	protein complex
0.42	GO:0005634	nucleus
0.41	GO:0043233	organelle lumen
0.38	GO:0097708	intracellular vesicle
0.38	GO:0044446	intracellular organelle part
0.38	GO:0030687	preribosome, large subunit precursor
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.50

GO:0008233

sp|O18475|DPOLQ_DROME
DNA polymerase theta
Search

0.49	DNA polymerase theta

0.70	GO:0006261	DNA-dependent DNA replication
0.66	GO:0071897	DNA biosynthetic process
0.64	GO:0097681	double-strand break repair via alternative nonhomologous end joining
0.50	GO:2000042	negative regulation of double-strand break repair via homologous recombination
0.48	GO:0006289	nucleotide-excision repair
0.47	GO:0016446	somatic hypermutation of immunoglobulin genes
0.46	GO:0051260	protein homooligomerization
0.44	GO:0006284	base-excision repair
0.38	GO:0010501	RNA secondary structure unwinding
0.34	GO:0000724	double-strand break repair via homologous recombination

0.71	GO:0003887	DNA-directed DNA polymerase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0003677	DNA binding
0.50	GO:0051575	5'-deoxyribose-5-phosphate lyase activity
0.47	GO:0043142	single-stranded DNA-dependent ATPase activity
0.46	GO:0008409	5'-3' exonuclease activity
0.45	GO:0003682	chromatin binding
0.41	GO:0004386	helicase activity

0.42	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.71

GO:0003887

sp|O18640|GBLP_DROME
Guanine nucleotide-binding protein subunit beta-like protein
Search

0.77	Receptor for activated protein kinase C

0.66	GO:0016243	regulation of autophagosome size
0.64	GO:0044829	positive regulation by host of viral genome replication
0.64	GO:0075522	IRES-dependent viral translational initiation
0.63	GO:0045725	positive regulation of glycogen biosynthetic process
0.63	GO:0018991	oviposition
0.62	GO:0046716	muscle cell cellular homeostasis
0.61	GO:0042335	cuticle development
0.60	GO:0035220	wing disc development
0.59	GO:0007626	locomotory behavior
0.58	GO:0048477	oogenesis

0.55	GO:0016301	kinase activity
0.38	GO:0004402	histone acetyltransferase activity
0.37	GO:0003743	translation initiation factor activity

0.60	GO:0005776	autophagosome
0.39	GO:0071011	precatalytic spliceosome
0.38	GO:0071013	catalytic step 2 spliceosome
0.36	GO:0005829	cytosol
0.35	GO:0005840	ribosome

0.38

GO:0004402

tr|O18645|O18645_DROME
Non-specific serine/threonine protein kinase
Search

0.61	Non-specific serine/threonine protein kinase

0.64	GO:0042595	behavioral response to starvation
0.63	GO:0006468	protein phosphorylation
0.63	GO:0030730	sequestering of triglyceride
0.63	GO:0042331	phototaxis
0.62	GO:0045792	negative regulation of cell size
0.61	GO:0044058	regulation of digestive system process
0.61	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.60	GO:0032007	negative regulation of TOR signaling
0.60	GO:0048813	dendrite morphogenesis
0.57	GO:0007411	axon guidance

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0060089	molecular transducer activity
0.43	GO:0035173	histone kinase activity

0.48	GO:0005634	nucleus
0.46	GO:0031588	nucleotide-activated protein kinase complex
0.34	GO:0000139	Golgi membrane

0.69

GO:0004674

tr|O18680|O18680_DROME
5-aminolevulinate synthase
Search

0.66	5-aminolevulinate synthase, erythroid-specific

0.72	GO:0006782	protoporphyrinogen IX biosynthetic process
0.49	GO:0040003	chitin-based cuticle development
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.83	GO:0003870	5-aminolevulinate synthase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.36	GO:0016874	ligase activity
0.33	GO:0008483	transaminase activity
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0003676	nucleic acid binding

0.73	GO:0005759	mitochondrial matrix
0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.83	EC:2.3.1.37	GO:0003870
0.83	KEGG:R00830	GO:0003870

sp|O44081|DKC1_DROME
H/ACA ribonucleoprotein complex subunit 4
Search

DKC1

0.32	Pseudouridine synthase

0.72	GO:0001522	pseudouridine synthesis
0.63	GO:0006396	RNA processing
0.50	GO:0033979	box H/ACA snoRNA metabolic process
0.47	GO:0090669	telomerase RNA stabilization
0.46	GO:0016072	rRNA metabolic process
0.46	GO:1904851	positive regulation of establishment of protein localization to telomere
0.46	GO:0007004	telomere maintenance via telomerase
0.46	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.46	GO:0042254	ribosome biogenesis
0.45	GO:0051973	positive regulation of telomerase activity

0.72	GO:0009982	pseudouridine synthase activity
0.59	GO:0003723	RNA binding
0.45	GO:0003720	telomerase activity
0.36	GO:0004730	pseudouridylate synthase activity
0.34	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.51	GO:0019013	viral nucleocapsid
0.49	GO:0030529	intracellular ribonucleoprotein complex
0.48	GO:0005730	nucleolus
0.44	GO:0015030	Cajal body
0.40	GO:1902494	catalytic complex
0.32	GO:0005737	cytoplasm

0.72	EC:5.4.99.12	GO:0009982
0.36	KEGG:R01055	GO:0004730

tr|O44226|O44226_DROME
Elongin B
Search

0.59	RNA polymerase II transcription elongation factor elongin

0.60	GO:0006414	translational elongation
0.52	GO:0007526	larval somatic muscle development
0.52	GO:0007474	imaginal disc-derived wing vein specification
0.36	GO:0016567	protein ubiquitination
0.36	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0045893	positive regulation of transcription, DNA-templated
0.35	GO:0071456	cellular response to hypoxia
0.35	GO:0043620	regulation of DNA-templated transcription in response to stress
0.35	GO:0043687	post-translational protein modification
0.34	GO:0006368	transcription elongation from RNA polymerase II promoter

0.61	GO:0003746	translation elongation factor activity
0.41	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0003713	transcription coactivator activity
0.35	GO:0032403	protein complex binding
0.34	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0003743	translation initiation factor activity
0.32	GO:0003677	DNA binding
0.32	GO:0046872	metal ion binding

0.61	GO:0070449	elongin complex
0.55	GO:0030891	VCB complex
0.43	GO:0031466	Cul5-RING ubiquitin ligase complex
0.43	GO:0031462	Cul2-RING ubiquitin ligase complex
0.36	GO:0070062	extracellular exosome
0.35	GO:0005667	transcription factor complex
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.34

GO:0004842

sp|O44252|ROST_DROME
Protein rolling stone
Search

ROST

0.69	Rolling stone, isoform B

0.69	GO:0007520	myoblast fusion
0.37	GO:0007275	multicellular organism development

0.30

GO:0044425

membrane part

sp|O44342|WBL_DROME
Protein windbeutel
Search

0.71	Endoplasmic reticulum resident protein 29

0.70	GO:0009306	protein secretion
0.58	GO:0034975	protein folding in endoplasmic reticulum
0.58	GO:0009950	dorsal/ventral axis specification
0.57	GO:0040014	regulation of multicellular organism growth
0.52	GO:0016485	protein processing
0.39	GO:0007309	oocyte axis specification
0.38	GO:0009792	embryo development ending in birth or egg hatching
0.35	GO:0006886	intracellular protein transport
0.35	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.32	GO:0045454	cell redox homeostasis

0.52	GO:0042803	protein homodimerization activity
0.35	GO:0016853	isomerase activity
0.35	GO:0003796	lysozyme activity
0.34	GO:0005509	calcium ion binding
0.33	GO:0140096	catalytic activity, acting on a protein

0.84	GO:0005788	endoplasmic reticulum lumen
0.38	GO:0042470	melanosome
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0016853

sp|O44386|ITA3_DROME
Integrin alpha-PS3
Search

0.81	Putative vitronectin receptor alpha subunit

0.80	GO:0007229	integrin-mediated signaling pathway
0.72	GO:0007155	cell adhesion
0.62	GO:0001555	oocyte growth
0.61	GO:0007508	larval heart development
0.60	GO:0035001	dorsal trunk growth, open tracheal system
0.59	GO:0003344	pericardium morphogenesis
0.58	GO:0045886	negative regulation of synaptic growth at neuromuscular junction
0.58	GO:0048149	behavioral response to ethanol
0.57	GO:0007391	dorsal closure
0.57	GO:0043277	apoptotic cell clearance

0.51	GO:0046982	protein heterodimerization activity
0.39	GO:0050839	cell adhesion molecule binding
0.36	GO:0004872	receptor activity
0.34	GO:0070006	metalloaminopeptidase activity
0.32	GO:0050840	extracellular matrix binding
0.32	GO:0046872	metal ion binding
0.32	GO:0032403	protein complex binding
0.32	GO:0042802	identical protein binding
0.32	GO:0005102	receptor binding
0.32	GO:0003676	nucleic acid binding

0.81	GO:0008305	integrin complex
0.57	GO:0009925	basal plasma membrane
0.55	GO:0016324	apical plasma membrane
0.39	GO:0005737	cytoplasm
0.39	GO:0016328	lateral plasma membrane
0.39	GO:0005925	focal adhesion
0.33	GO:0009897	external side of plasma membrane
0.33	GO:0031982	vesicle
0.33	GO:0032587	ruffle membrane
0.32	GO:0043230	extracellular organelle

sp|O44424|DGC14_DROME
Protein DGCR14 homolog
Search

0.70	Splicing factor ESS-2 homolog

0.55	GO:0000398	mRNA splicing, via spliceosome
0.54	GO:0007399	nervous system development
0.42	GO:0006351	transcription, DNA-templated
0.42	GO:1903506	regulation of nucleic acid-templated transcription
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.42	GO:0010468	regulation of gene expression
0.42	GO:0007179	transforming growth factor beta receptor signaling pathway

0.44	GO:0003700	DNA binding transcription factor activity
0.41	GO:0003677	DNA binding
0.37	GO:0046872	metal ion binding

0.61	GO:0071013	catalytic step 2 spliceosome
0.40	GO:0005667	transcription factor complex
0.39	GO:0005615	extracellular space
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|O44434|O44434_DROME
QKR58E-3
Search

0.81	KH domain-containing, RNA-binding, signal transduction-associated protein 2

0.48	GO:0048024	regulation of mRNA splicing, via spliceosome
0.45	GO:0046833	positive regulation of RNA export from nucleus
0.43	GO:0045948	positive regulation of translational initiation
0.42	GO:0006915	apoptotic process
0.41	GO:0009967	positive regulation of signal transduction
0.40	GO:0051259	protein oligomerization
0.40	GO:0007166	cell surface receptor signaling pathway
0.40	GO:0045892	negative regulation of transcription, DNA-templated
0.36	GO:0007283	spermatogenesis
0.35	GO:0007349	cellularization

0.59	GO:0003723	RNA binding
0.43	GO:0005070	SH3/SH2 adaptor activity
0.41	GO:0019904	protein domain specific binding
0.40	GO:0042802	identical protein binding
0.34	GO:0032403	protein complex binding
0.32	GO:0003677	DNA binding

0.47	GO:0016607	nuclear speck
0.35	GO:0070618	Grb2-Sos complex
0.35	GO:0005737	cytoplasm
0.34	GO:0071011	precatalytic spliceosome
0.33	GO:0071013	catalytic step 2 spliceosome
0.30	GO:0031224	intrinsic component of membrane

sp|O44437|SMD3_DROME
Small nuclear ribonucleoprotein Sm D3
Search

0.78	LOW QUALITY PROTEIN: small nuclear ribonucleoprotein Sm D3

0.81	GO:0000387	spliceosomal snRNP assembly
0.48	GO:0045451	pole plasm oskar mRNA localization
0.48	GO:0048542	lymph gland development
0.46	GO:0007422	peripheral nervous system development
0.45	GO:0007517	muscle organ development
0.45	GO:0007417	central nervous system development
0.44	GO:0030182	neuron differentiation
0.44	GO:0000245	spliceosomal complex assembly
0.42	GO:0006479	protein methylation
0.34	GO:0000278	mitotic cell cycle

0.48	GO:0071209	U7 snRNA binding
0.47	GO:0071208	histone pre-mRNA DCP binding
0.47	GO:0030620	U2 snRNA binding
0.47	GO:0070034	telomerase RNA binding
0.42	GO:0019899	enzyme binding
0.35	GO:1990446	U1 snRNP binding

0.76	GO:0005681	spliceosomal complex
0.60	GO:0019013	viral nucleocapsid
0.50	GO:0005687	U4 snRNP
0.50	GO:0034715	pICln-Sm protein complex
0.50	GO:0034719	SMN-Sm protein complex
0.48	GO:0005685	U1 snRNP
0.48	GO:0005683	U7 snRNP
0.47	GO:0045495	pole plasm
0.47	GO:0034709	methylosome
0.47	GO:0005697	telomerase holoenzyme complex

sp|O44783|SPY_DROME
Protein sprouty
Search

0.11

Sprouty

0.67	GO:0007275	multicellular organism development
0.66	GO:0009966	regulation of signal transduction
0.59	GO:0001736	establishment of planar polarity
0.59	GO:0048747	muscle fiber development
0.59	GO:0061138	morphogenesis of a branching epithelium
0.58	GO:0090288	negative regulation of cellular response to growth factor stimulus
0.58	GO:2000027	regulation of organ morphogenesis
0.57	GO:0007163	establishment or maintenance of cell polarity
0.55	GO:0051960	regulation of nervous system development
0.55	GO:0060284	regulation of cell development

0.37	GO:0003677	DNA binding
0.36	GO:0019899	enzyme binding
0.36	GO:0098772	molecular function regulator
0.35	GO:0005543	phospholipid binding
0.35	GO:0003700	DNA binding transcription factor activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.33	GO:0050825	ice binding

0.44	GO:0005886	plasma membrane
0.39	GO:0005634	nucleus
0.36	GO:0045177	apical part of cell
0.35	GO:0005912	adherens junction
0.34	GO:0000428	DNA-directed RNA polymerase complex
0.34	GO:0005667	transcription factor complex
0.34	GO:0015630	microtubule cytoskeleton
0.34	GO:0005829	cytosol
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part

0.33

EC:2.7

GO:0016772

sp|O46036|CTBP_DROME
C-terminal-binding protein
Search

CTBP

0.47	2-hydroxyacid dehydrogenase

0.53	GO:0055114	oxidation-reduction process
0.36	GO:1903507	negative regulation of nucleic acid-templated transcription
0.35	GO:0016360	sensory organ precursor cell fate determination
0.35	GO:0022416	chaeta development
0.35	GO:0001700	embryonic development via the syncytial blastoderm
0.35	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.35	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.35	GO:0035220	wing disc development
0.35	GO:0043044	ATP-dependent chromatin remodeling
0.34	GO:0045944	positive regulation of transcription by RNA polymerase II

0.68	GO:0051287	NAD binding
0.66	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.37	GO:0003714	transcription corepressor activity
0.36	GO:0042803	protein homodimerization activity
0.35	GO:0070491	repressing transcription factor binding
0.34	GO:0003713	transcription coactivator activity

0.35	GO:0005829	cytosol
0.35	GO:0005700	polytene chromosome
0.35	GO:0031010	ISWI-type complex

0.66

EC:1.1.1

GO:0016616

sp|O46037|VINC_DROME
Vinculin
Search

VINC

0.84

Vinculin

0.72	GO:0007155	cell adhesion
0.36	GO:0007016	cytoskeletal anchoring at plasma membrane

0.78	GO:0051015	actin filament binding
0.57	GO:0005198	structural molecule activity

0.68	GO:0015629	actin cytoskeleton
0.49	GO:0098592	cytoplasmic side of apical plasma membrane
0.35	GO:0005925	focal adhesion
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|O46040|MSTAA_DROME
Protein msta, isoform A
Search

0.74	GO:0034968	histone lysine methylation
0.64	GO:0010629	negative regulation of gene expression

0.80	GO:0042826	histone deacetylase binding
0.64	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity

0.71	GO:0000790	nuclear chromatin
0.38	GO:0005737	cytoplasm

sp|O46043|PARG_DROME
Poly(ADP-ribose) glycohydrolase
Search

0.75	Poly glycohydrolase

0.60	GO:0005975	carbohydrate metabolic process
0.51	GO:0036099	female germ-line stem cell population maintenance
0.51	GO:0030576	Cajal body organization
0.50	GO:0051457	maintenance of protein location in nucleus
0.49	GO:0035065	regulation of histone acetylation
0.48	GO:0043484	regulation of RNA splicing
0.48	GO:0006342	chromatin silencing
0.46	GO:0009408	response to heat
0.45	GO:1990966	ATP generation from poly-ADP-D-ribose
0.34	GO:0016045	detection of bacterium

0.85	GO:0004649	poly(ADP-ribose) glycohydrolase activity
0.36	GO:0046872	metal ion binding
0.34	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.34	GO:0003682	chromatin binding
0.32	GO:0008168	methyltransferase activity
0.31	GO:0003677	DNA binding

0.46	GO:0005654	nucleoplasm
0.39	GO:0005829	cytosol
0.33	GO:0000785	chromatin
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:3.2.1.143

GO:0004649

tr|O46048|O46048_DROME
EG:133E12.4 protein
Search

0.88	GO:0000705	achiasmate meiosis I
0.86	GO:0016321	female meiosis chromosome segregation
0.86	GO:0090235	regulation of metaphase plate congression
0.83	GO:0007552	metamorphosis
0.68	GO:0010629	negative regulation of gene expression

0.84	GO:0005700	polytene chromosome
0.70	GO:0005654	nucleoplasm
0.57	GO:0000228	nuclear chromosome
0.57	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

tr|O46050|O46050_DROME
EG:152A3.1 protein
Search

0.69	60S ribosomal export protein NMD3

0.65	GO:0015031	protein transport
0.42	GO:0033750	ribosome localization
0.42	GO:0071166	ribonucleoprotein complex localization
0.42	GO:0051169	nuclear transport
0.41	GO:0051656	establishment of organelle localization
0.40	GO:0051236	establishment of RNA localization
0.40	GO:0050657	nucleic acid transport
0.39	GO:0034613	cellular protein localization
0.39	GO:0042254	ribosome biogenesis

0.42	GO:0043023	ribosomal large subunit binding
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0016787	hydrolase activity
0.32	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0044446	intracellular organelle part
0.34	GO:1990904	ribonucleoprotein complex

0.33

GO:0016773

sp|O46051|C4D14_DROME
Probable cytochrome P450 4d14
Search

0.39	p450 monooxygenase

0.53	GO:0055114	oxidation-reduction process
0.33	GO:0030258	lipid modification
0.33	GO:0006631	fatty acid metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding

0.37	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

tr|O46052|O46052_DROME
CG3630, isoform A
Search

ABRA

0.60	Actin-binding Rho-activating protein (Fragment)

0.84	GO:0035025	positive regulation of Rho protein signal transduction
0.56	GO:0000060	protein import into nucleus, translocation
0.53	GO:0051091	positive regulation of DNA binding transcription factor activity
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:0008015	blood circulation
0.41	GO:0007507	heart development
0.36	GO:0035775	pronephric glomerulus morphogenesis
0.35	GO:0006751	glutathione catabolic process
0.34	GO:0006351	transcription, DNA-templated
0.33	GO:0006508	proteolysis

0.71	GO:0003779	actin binding
0.35	GO:0036374	glutathione hydrolase activity

0.54	GO:0015629	actin cytoskeleton
0.53	GO:0030016	myofibril
0.42	GO:0005886	plasma membrane
0.37	GO:0044449	contractile fiber part
0.30	GO:0016021	integral component of membrane

0.35	EC:3.4.19.13	GO:0036374
0.35	KEGG:R00494	GO:0036374

sp|O46054|C4AE1_DROME
Cytochrome P450 4ae1
Search

0.11	Putative cytochrome

0.53	GO:0055114	oxidation-reduction process
0.33	GO:0035725	sodium ion transmembrane transport
0.32	GO:0006508	proteolysis

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.33	GO:0005272	sodium channel activity
0.33	GO:0017171	serine hydrolase activity
0.32	GO:0070011	peptidase activity, acting on L-amino acid peptides

0.39	GO:0005783	endoplasmic reticulum
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.35	GO:0031090	organelle membrane
0.32	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

tr|O46067|O46067_DROME
CG2918, isoform A
Search

0.73	hypoxia up-regulated protein 1

0.38	GO:1903297	regulation of hypoxia-induced intrinsic apoptotic signaling pathway
0.38	GO:1900038	negative regulation of cellular response to hypoxia
0.37	GO:1903382	negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway
0.37	GO:0071456	cellular response to hypoxia
0.37	GO:0002931	response to ischemia
0.36	GO:0034976	response to endoplasmic reticulum stress
0.36	GO:0006888	ER to Golgi vesicle-mediated transport
0.35	GO:0032504	multicellular organism reproduction
0.34	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.34	GO:0006368	transcription elongation from RNA polymerase II promoter

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity

0.46	GO:0005615	extracellular space
0.37	GO:0012505	endomembrane system
0.35	GO:0031974	membrane-enclosed lumen
0.35	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0044446	intracellular organelle part
0.34	GO:0044444	cytoplasmic part
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.34

GO:0032440

tr|O46070|O46070_DROME
CG2865, isoform A
Search

0.11	SERTA motif protein

0.44

GO:0006891

intra-Golgi vesicle-mediated transport

0.44

GO:0030173

integral component of Golgi membrane

sp|O46072|KZ_DROME
Probable ATP-dependent RNA helicase kurz
Search

0.42	ATP-dependent RNA helicase kurz

0.38	GO:0006396	RNA processing
0.37	GO:0048026	positive regulation of mRNA splicing, via spliceosome

0.67	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.43	GO:0016887	ATPase activity
0.37	GO:0140098	catalytic activity, acting on RNA

0.40	GO:0005730	nucleolus
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.43

GO:0016887

sp|O46077|OR2A_DROME
Odorant receptor 2a
Search

0.51	Odorant receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.61	GO:0007165	signal transduction

0.80	GO:0005549	odorant binding
0.76	GO:0004984	olfactory receptor activity

0.56	GO:0005886	plasma membrane
0.45	GO:0030425	dendrite
0.45	GO:0031252	cell leading edge
0.30	GO:0031224	intrinsic component of membrane

tr|O46079|O46079_DROME
CG3587
Search

KTI12

0.97	Putative rna polymerase ii elongator associated protein (Fragment)

0.81	GO:0080178	5-carbamoylmethyl uridine residue modification
0.77	GO:0010449	root meristem growth
0.75	GO:0009933	meristem structural organization
0.71	GO:0048366	leaf development
0.68	GO:0002098	tRNA wobble uridine modification
0.65	GO:0006357	regulation of transcription by RNA polymerase II
0.40	GO:0006351	transcription, DNA-templated
0.39	GO:0042254	ribosome biogenesis
0.36	GO:0046939	nucleotide phosphorylation
0.35	GO:0055114	oxidation-reduction process

0.69	GO:0005516	calmodulin binding
0.45	GO:0003682	chromatin binding
0.43	GO:0019153	protein-disulfide reductase (glutathione) activity
0.41	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0004017	adenylate kinase activity
0.35	GO:0003676	nucleic acid binding
0.35	GO:0016787	hydrolase activity

0.71	GO:0033588	Elongator holoenzyme complex
0.47	GO:0005634	nucleus
0.39	GO:0031974	membrane-enclosed lumen
0.39	GO:0005737	cytoplasm
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.43

EC:1.8.4.2

GO:0019153

sp|O46080|SMG9_DROME
Protein SMG9
Search

0.86	GO:0042332	gravitaxis
0.50	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

0.42	GO:0032550	purine ribonucleoside binding
0.42	GO:0019001	guanyl nucleotide binding
0.38	GO:0032555	purine ribonucleotide binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003924	GTPase activity

0.37	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|O46084|PGAM5_DROME
Serine/threonine-protein phosphatase Pgam5, mitochondrial
Search

PGAM5

0.40	Phosphoglycerate mutase

0.69	GO:0090141	positive regulation of mitochondrial fission
0.67	GO:0035970	peptidyl-threonine dephosphorylation
0.65	GO:0072347	response to anesthetic
0.61	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.58	GO:0009408	response to heat
0.38	GO:0012501	programmed cell death
0.33	GO:0007165	signal transduction

0.64	GO:0043539	protein serine/threonine kinase activator activity
0.60	GO:0019900	kinase binding
0.59	GO:0004722	protein serine/threonine phosphatase activity
0.39	GO:0004619	phosphoglycerate mutase activity
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0005741	mitochondrial outer membrane
0.36	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.39

EC:5.4.2.1

GO:0004619

tr|O46085|O46085_DROME
GH08708p
Search

0.39	peroxisomal targeting signal 1 receptor

0.82	GO:0072347	response to anesthetic
0.78	GO:0007031	peroxisome organization
0.53	GO:0015919	peroxisomal membrane transport
0.52	GO:0044743	protein transmembrane import into intracellular organelle
0.49	GO:0065002	intracellular protein transmembrane transport
0.48	GO:0006605	protein targeting
0.39	GO:0035023	regulation of Rho protein signal transduction
0.38	GO:0007264	small GTPase mediated signal transduction
0.37	GO:0065009	regulation of molecular function
0.36	GO:0006635	fatty acid beta-oxidation

0.58	GO:0005052	peroxisome matrix targeting signal-1 binding
0.39	GO:0005515	protein binding
0.39	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.38	GO:0060090	molecular adaptor activity
0.37	GO:0098772	molecular function regulator
0.35	GO:0003677	DNA binding

0.55	GO:0005777	peroxisome
0.53	GO:0031903	microbody membrane
0.47	GO:0005829	cytosol
0.39	GO:1990429	peroxisomal importomer complex
0.38	GO:0000786	nucleosome
0.36	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.39

GO:0016747

sp|O46089|MMS22_DROME
Protein MMS22-like
Search

0.79	GO:0031297	replication fork processing
0.72	GO:0000724	double-strand break repair via homologous recombination

0.77	GO:0043596	nuclear replication fork
0.30	GO:0031224	intrinsic component of membrane

tr|O46094|O46094_DROME
EG:86E4.5 protein
Search

0.42	Inositol polyphosphate 5-phosphatase

0.81	GO:0046856	phosphatidylinositol dephosphorylation
0.58	GO:0007165	signal transduction
0.53	GO:2000431	regulation of cytokinesis, actomyosin contractile ring assembly
0.52	GO:0032187	actomyosin contractile ring localization
0.49	GO:0000281	mitotic cytokinesis
0.46	GO:0006897	endocytosis
0.39	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process
0.38	GO:0043547	positive regulation of GTPase activity
0.35	GO:0032402	melanosome transport
0.35	GO:0039023	pronephric duct morphogenesis

0.64	GO:0052745	inositol phosphate phosphatase activity
0.53	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity
0.41	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity
0.40	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity
0.40	GO:0004438	phosphatidylinositol-3-phosphatase activity
0.38	GO:0005096	GTPase activator activity
0.35	GO:0004527	exonuclease activity
0.34	GO:0004519	endonuclease activity
0.32	GO:0070003	threonine-type peptidase activity
0.32	GO:0016846	carbon-sulfur lyase activity

0.50	GO:0055037	recycling endosome
0.49	GO:0005770	late endosome
0.49	GO:0005769	early endosome
0.39	GO:0030479	actin cortical patch
0.32	GO:0019773	proteasome core complex, alpha-subunit complex
0.30	GO:0016020	membrane

0.64

GO:0052745

sp|O46098|BCN92_DROME
Protein bcn92
Search

0.64	LYR motif-containing protein 4

0.44	GO:0008270	zinc ion binding
0.39	GO:0003676	nucleic acid binding

tr|O46099|O46099_DROME
EG:8D8.2 protein
Search

0.48	GO:0005975	carbohydrate metabolic process
0.44	GO:0006508	proteolysis

0.54	GO:0030246	carbohydrate binding
0.52	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.48	GO:0070001	aspartic-type peptidase activity
0.46	GO:0004175	endopeptidase activity

0.59	GO:0070701	mucus layer
0.30	GO:0044425	membrane part

0.52

GO:0004553

tr|O46100|O46100_DROME
EG:8D8.3 protein
Search

0.55	Na-K-Cl cotransporter

0.55	GO:0055085	transmembrane transport
0.41	GO:0006821	chloride transport
0.40	GO:0071804	cellular potassium ion transport
0.37	GO:0006865	amino acid transport
0.37	GO:0060271	cilium assembly
0.36	GO:0016192	vesicle-mediated transport
0.35	GO:0006886	intracellular protein transport

0.43	GO:0015379	potassium:chloride symporter activity
0.41	GO:0022820	potassium ion symporter activity
0.37	GO:0015171	amino acid transmembrane transporter activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0005247	voltage-gated chloride channel activity

0.35	GO:0030117	membrane coat
0.30	GO:0016021	integral component of membrane

sp|O46101|TSN2A_DROME
Tetraspanin-2A
Search

0.59	Tetraspanin

0.65	GO:0090528	smooth septate junction assembly
0.63	GO:0090557	establishment of endothelial intestinal barrier
0.38	GO:0007166	cell surface receptor signaling pathway

0.35

GO:0005515

protein binding

0.64	GO:0005920	smooth septate junction
0.61	GO:0016327	apicolateral plasma membrane
0.37	GO:0005887	integral component of plasma membrane

sp|O46102|PAPD1_DROME
Poly(A) RNA polymerase, mitochondrial
Search

0.93	Poly(A) RNA polymerase, mitochondrial

0.82	GO:0036415	regulation of tRNA stability
0.82	GO:1902371	negative regulation of tRNA catabolic process
0.79	GO:0090616	mitochondrial mRNA 3'-end processing
0.74	GO:0043489	RNA stabilization
0.69	GO:0006378	mRNA polyadenylation
0.41	GO:0006309	apoptotic DNA fragmentation
0.37	GO:0043248	proteasome assembly
0.37	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.36	GO:0051028	mRNA transport
0.36	GO:0006405	RNA export from nucleus

0.68	GO:1990817	RNA adenylyltransferase activity
0.41	GO:0003676	nucleic acid binding
0.40	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity
0.39	GO:0070546	L-phenylalanine aminotransferase activity
0.38	GO:0008144	drug binding
0.38	GO:0043168	anion binding
0.38	GO:0050265	RNA uridylyltransferase activity
0.37	GO:0036094	small molecule binding
0.37	GO:0046872	metal ion binding
0.37	GO:0097367	carbohydrate derivative binding

0.53	GO:0005739	mitochondrion
0.37	GO:0008541	proteasome regulatory particle, lid subcomplex
0.37	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.40	EC:2.6.1.1	GO:0004069
0.40	KEGG:R00355	GO:0004069

sp|O46106|NOI_DROME
Splicing factor 3A subunit 3
Search

SF3A3

0.77	Splicing factor 3A subunit

0.75	GO:0000398	mRNA splicing, via spliceosome
0.46	GO:0009566	fertilization
0.42	GO:0060218	hematopoietic stem cell differentiation
0.35	GO:0046856	phosphatidylinositol dephosphorylation
0.34	GO:0000278	mitotic cell cycle
0.33	GO:0022618	ribonucleoprotein complex assembly
0.33	GO:0007165	signal transduction

0.63	GO:0008270	zinc ion binding
0.59	GO:0003723	RNA binding
0.35	GO:0052745	inositol phosphate phosphatase activity
0.34	GO:0008970	phosphatidylcholine 1-acylhydrolase activity
0.33	GO:0005515	protein binding

0.76	GO:0005681	spliceosomal complex
0.45	GO:0005654	nucleoplasm
0.42	GO:1902494	catalytic complex
0.35	GO:0005686	U2 snRNP
0.33	GO:0005576	extracellular region

0.35

GO:0052745

sp|O46107|LIP1_DROME
Lipase 1
Search

0.48	Putative triglyceride lipase-cholesterol esterase

0.65	GO:0016042	lipid catabolic process
0.51	GO:0007586	digestion
0.43	GO:0070328	triglyceride homeostasis
0.42	GO:0042632	cholesterol homeostasis
0.34	GO:0006915	apoptotic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.60	GO:0016788	hydrolase activity, acting on ester bonds
0.34	GO:0044212	transcription regulatory region DNA binding
0.33	GO:0003700	DNA binding transcription factor activity

0.40	GO:0031410	cytoplasmic vesicle
0.35	GO:0005576	extracellular region
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.60

GO:0016788

sp|O46108|LIP3_DROME
Lipase 3
Search

0.48	Gastric triacylglycerol lipase

0.62	GO:0006629	lipid metabolic process
0.54	GO:1901575	organic substance catabolic process
0.37	GO:0070328	triglyceride homeostasis
0.37	GO:0042632	cholesterol homeostasis
0.34	GO:0032504	multicellular organism reproduction

0.57

GO:0016788

hydrolase activity, acting on ester bonds

0.35	GO:0031410	cytoplasmic vesicle
0.34	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.57

GO:0016788

sp|O46197|A29AB_DROME
Accessory gland protein Acp29AB
Search

ACP29AB

0.94	Accessory gland protein Acp29AB

0.87	GO:0046693	sperm storage
0.58	GO:0007610	behavior

0.53	GO:0030246	carbohydrate binding
0.39	GO:0036094	small molecule binding

0.51

GO:0005576

extracellular region

sp|O46199|A53E_DROME
Accessory gland protein Acp53Ea
Search

ACP53EA

0.63	Accessory gland protein Acp53Ea

0.87	GO:0046692	sperm competition
0.79	GO:0007610	behavior

0.73

GO:0005615

extracellular space

sp|O46200|A63F_DROME
Accessory gland protein Acp63F
Search

0.79	GO:0007610	behavior
0.77	GO:0032504	multicellular organism reproduction

0.73

GO:0005615

extracellular space

sp|O46201|A98AB_DROME
Accessory gland protein 98AB
Search

0.40	Accessory gland protein 98AB

0.87	GO:0045434	negative regulation of female receptivity, post-mating
0.75	GO:0010469	regulation of receptor activity

0.79

GO:0005179

hormone activity

0.73

GO:0005615

extracellular space

sp|O46202|A62F_DROME
Accessory gland protein Acp62F
Search

ACP62F

0.97	Accessory gland peptide 62F

0.86	GO:0046692	sperm competition
0.74	GO:0010951	negative regulation of endopeptidase activity
0.44	GO:0007610	behavior
0.38	GO:0006030	chitin metabolic process
0.37	GO:0007399	nervous system development
0.37	GO:0030154	cell differentiation

0.77	GO:0004867	serine-type endopeptidase inhibitor activity
0.38	GO:0008061	chitin binding

0.73

GO:0005615

extracellular space

sp|O46203|A32CD_DROME
Accessory gland protein Acp32CD
Search

0.10	Accessory gland protein Acp32CD

0.68	GO:0045434	negative regulation of female receptivity, post-mating
0.57	GO:0010469	regulation of receptor activity
0.57	GO:0045893	positive regulation of transcription, DNA-templated
0.56	GO:0032912	negative regulation of transforming growth factor beta2 production
0.56	GO:0007493	endodermal cell fate determination
0.56	GO:0110024	positive regulation of cardiac muscle myoblast proliferation
0.56	GO:0032911	negative regulation of transforming growth factor beta1 production
0.56	GO:0060486	Clara cell differentiation
0.56	GO:0060947	cardiac vascular smooth muscle cell differentiation
0.56	GO:0060510	Type II pneumocyte differentiation

0.59	GO:0005179	hormone activity
0.54	GO:0001103	RNA polymerase II repressing transcription factor binding
0.53	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.51	GO:0043565	sequence-specific DNA binding
0.50	GO:0008270	zinc ion binding
0.50	GO:0019901	protein kinase binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003682	chromatin binding
0.47	GO:0003690	double-stranded DNA binding
0.47	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.56	GO:0005615	extracellular space
0.52	GO:0005634	nucleus
0.48	GO:0005667	transcription factor complex
0.45	GO:0000793	condensed chromosome
0.43	GO:0044427	chromosomal part
0.43	GO:0012505	endomembrane system
0.42	GO:0070013	intracellular organelle lumen
0.41	GO:0031967	organelle envelope
0.41	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

sp|O46227|A33A_DROME
Accessory gland peptide Acp33A
Search

0.17	Accessory gland peptide Acp33A

0.87	GO:0045434	negative regulation of female receptivity, post-mating
0.75	GO:0010469	regulation of receptor activity

0.79

GO:0005179

hormone activity

0.73

GO:0005615

extracellular space

tr|O46307|O46307_DROME
EG:8D8.4 protein
Search

0.49	Deoxyribonuclease II

0.33

GO:0045454

cell redox homeostasis

0.31

GO:0046872

metal ion binding

0.61	GO:0005634	nucleus
0.30	GO:0044425	membrane part

tr|O46308|O46308_DROME
EG:8D8.5 protein
Search

0.52	Sperm motility kinase

0.63	GO:0006468	protein phosphorylation
0.50	GO:0045977	positive regulation of mitotic cell cycle, embryonic
0.50	GO:0007343	egg activation
0.45	GO:1990260	negative regulation of transcription from RNA polymerase II promoter by transcription factor localization involved in response to DNA damage checkpoint signaling
0.45	GO:0072434	signal transduction involved in mitotic G2 DNA damage checkpoint
0.43	GO:0048478	replication fork protection
0.37	GO:0032147	activation of protein kinase activity
0.37	GO:0043406	positive regulation of MAP kinase activity
0.36	GO:0010311	lateral root formation
0.36	GO:0007112	male meiosis cytokinesis

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0004871	signal transducer activity
0.35	GO:0017048	Rho GTPase binding
0.35	GO:0016849	phosphorus-oxygen lyase activity
0.34	GO:0099600	transmembrane receptor activity
0.33	GO:0003677	DNA binding

0.47	GO:1902554	serine/threonine protein kinase complex
0.43	GO:0035861	site of double-strand break
0.41	GO:0000790	nuclear chromatin
0.36	GO:0009524	phragmoplast
0.33	GO:0005938	cell cortex
0.33	GO:0032155	cell division site part
0.33	GO:0000131	incipient cellular bud site
0.33	GO:0005934	cellular bud tip
0.33	GO:0005935	cellular bud neck
0.33	GO:0005829	cytosol

0.35	EC:4.6	GO:0016849
0.32	KEGG:R03876	GO:0004842

sp|O46339|HTH_DROME
Homeobox protein homothorax
Search

LOC108740886

0.84	Homeobox protein homothorax

0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.49	GO:0007383	specification of segmental identity, antennal segment
0.48	GO:2000497	positive regulation of cell proliferation involved in compound eye morphogenesis
0.48	GO:0007481	haltere disc morphogenesis
0.47	GO:0090098	positive regulation of decapentaplegic signaling pathway
0.47	GO:0007482	haltere development
0.46	GO:0001752	compound eye photoreceptor fate commitment
0.46	GO:0072002	Malpighian tubule development

0.54	GO:0003677	DNA binding
0.46	GO:0001223	transcription coactivator binding
0.45	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.42	GO:0001067	regulatory region nucleic acid binding
0.42	GO:0046982	protein heterodimerization activity

0.60	GO:0005634	nucleus
0.42	GO:0005667	transcription factor complex
0.41	GO:0032993	protein-DNA complex
0.35	GO:0005829	cytosol
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|O46341|A6_DROME
Protein a6
Search

0.85

GO:0001700

embryonic development via the syncytial blastoderm

0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003676	nucleic acid binding

0.30

GO:0044425

membrane part

sp|O61231|RL10_DROME
60S ribosomal protein L10
Search

RPL10

0.55	Similar to Drosophila melanogaster qm (Fragment)

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.36	GO:0000027	ribosomal large subunit assembly
0.35	GO:1990403	embryonic brain development
0.34	GO:0007420	brain development
0.33	GO:0006417	regulation of translation

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding
0.34	GO:0045182	translation regulator activity

0.61	GO:0005840	ribosome
0.44	GO:0043025	neuronal cell body
0.36	GO:0044445	cytosolic part
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0005634	nucleus

sp|O61267|LOK_DROME
Ovarian-specific serine/threonine-protein kinase Lok
Search

0.79	Ovarian-specific serine/threonine-protein kinase Lok

0.63	GO:0006468	protein phosphorylation
0.54	GO:0071480	cellular response to gamma radiation
0.54	GO:0035234	ectopic germ cell programmed cell death
0.53	GO:0030717	karyosome formation
0.53	GO:0044773	mitotic DNA damage checkpoint
0.53	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.53	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.52	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.50	GO:0051091	positive regulation of DNA binding transcription factor activity
0.49	GO:2001020	regulation of response to DNA damage stimulus

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0031625	ubiquitin protein ligase binding
0.37	GO:0019901	protein kinase binding
0.37	GO:0042803	protein homodimerization activity
0.32	GO:0030247	polysaccharide binding
0.32	GO:0008410	CoA-transferase activity

0.44	GO:0005634	nucleus
0.37	GO:0000781	chromosome, telomeric region
0.37	GO:0070013	intracellular organelle lumen
0.36	GO:0005794	Golgi apparatus
0.35	GO:0036038	MKS complex
0.33	GO:0042597	periplasmic space
0.32	GO:0016282	eukaryotic 43S preinitiation complex
0.32	GO:0033290	eukaryotic 48S preinitiation complex
0.32	GO:0005852	eukaryotic translation initiation factor 3 complex
0.30	GO:0016020	membrane

0.32

EC:2.8.3

GO:0008410

sp|O61305|DDX19_DROME
DEAD-box helicase Dbp80
Search

DBP80

0.39	DEAD box ATP-dependent RNA helicase

0.42	GO:0010501	RNA secondary structure unwinding
0.41	GO:0006413	translational initiation
0.40	GO:0008380	RNA splicing
0.36	GO:0060255	regulation of macromolecule metabolic process
0.35	GO:0051028	mRNA transport
0.34	GO:0015031	protein transport
0.32	GO:0006796	phosphate-containing compound metabolic process

0.56	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.41	GO:0008186	RNA-dependent ATPase activity
0.37	GO:0140098	catalytic activity, acting on RNA
0.34	GO:0004427	inorganic diphosphatase activity
0.33	GO:0000287	magnesium ion binding

0.42	GO:0071013	catalytic step 2 spliceosome
0.40	GO:0005730	nucleolus
0.36	GO:0044614	nuclear pore cytoplasmic filaments
0.35	GO:0031965	nuclear membrane
0.35	GO:0005737	cytoplasm

0.34	EC:3.6.1.1	GO:0004427
0.34	KEGG:R00004	GO:0004427

sp|O61307|TENM_DROME
Teneurin-m
Search

0.62	Teneurin-m

0.58	GO:0097264	self proteolysis
0.43	GO:0008045	motor neuron axon guidance
0.42	GO:0016200	synaptic target attraction
0.41	GO:0048058	compound eye corneal lens development
0.41	GO:0048499	synaptic vesicle membrane organization
0.41	GO:0048790	maintenance of presynaptic active zone structure
0.41	GO:0045467	R7 cell development
0.40	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.40	GO:0097090	presynaptic membrane organization
0.40	GO:2000331	regulation of terminal button organization

0.40	GO:0031005	filamin binding
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0046982	protein heterodimerization activity
0.30	GO:0003824	catalytic activity

0.39	GO:0031594	neuromuscular junction
0.39	GO:0043025	neuronal cell body
0.39	GO:0045211	postsynaptic membrane
0.38	GO:0005887	integral component of plasma membrane
0.38	GO:0043005	neuron projection
0.38	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0030054	cell junction
0.33	GO:0005737	cytoplasm

sp|O61345|PENG_DROME
Protein penguin
Search

0.75	GO:0007475	apposition of dorsal and ventral imaginal disc-derived wing surfaces
0.40	GO:0006417	regulation of translation
0.33	GO:0016567	protein ubiquitination
0.32	GO:0006886	intracellular protein transport
0.32	GO:0016192	vesicle-mediated transport

0.59	GO:0003723	RNA binding
0.33	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0016874	ligase activity

0.41	GO:0005730	nucleolus
0.33	GO:0030123	AP-3 adaptor complex

0.32	EC:6	GO:0016874
0.33	KEGG:R03876	GO:0004842

tr|O61348|O61348_DROME
Bobby sox
Search

BBX

0.68	HMG box transcription factor BBX

0.37	GO:0060348	bone development
0.33	GO:0000122	negative regulation of transcription by RNA polymerase II
0.32	GO:0055114	oxidation-reduction process

0.55	GO:0003677	DNA binding
0.33	GO:0016853	isomerase activity
0.32	GO:0016491	oxidoreductase activity

0.61	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.36	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part

0.33

GO:0016853

tr|O61351|O61351_DROME
La costa
Search

0.92

La costa

0.43	GO:0019538	protein metabolic process
0.42	GO:0043043	peptide biosynthetic process
0.40	GO:0010467	gene expression
0.40	GO:0009059	macromolecule biosynthetic process
0.40	GO:0044260	cellular macromolecule metabolic process
0.39	GO:0043412	macromolecule modification
0.38	GO:0016310	phosphorylation
0.37	GO:0006030	chitin metabolic process
0.36	GO:0007165	signal transduction
0.36	GO:0055114	oxidation-reduction process

0.45	GO:0005198	structural molecule activity
0.45	GO:0003723	RNA binding
0.41	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0008658	penicillin binding
0.39	GO:0071949	FAD binding
0.39	GO:0016301	kinase activity
0.39	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.38	GO:0097367	carbohydrate derivative binding
0.37	GO:0017171	serine hydrolase activity
0.37	GO:0030554	adenyl nucleotide binding

0.46	GO:0015935	small ribosomal subunit
0.44	GO:0005581	collagen trimer
0.37	GO:0005576	extracellular region
0.36	GO:0019028	viral capsid
0.35	GO:0030176	integral component of endoplasmic reticulum membrane
0.35	GO:0071944	cell periphery
0.35	GO:0009360	DNA polymerase III complex
0.35	GO:0000131	incipient cellular bud site
0.33	GO:0005634	nucleus

0.39	EC:2.7.1	GO:0016773
0.36	KEGG:R04148	GO:0008939

tr|O61360|O61360_DROME
CROL ALPHA
Search

0.81	CROL ALPHA

0.60	GO:0070868	heterochromatin organization involved in chromatin silencing
0.58	GO:0031935	regulation of chromatin silencing
0.58	GO:0007476	imaginal disc-derived wing morphogenesis
0.57	GO:0030178	negative regulation of Wnt signaling pathway
0.57	GO:0045931	positive regulation of mitotic cell cycle
0.52	GO:0007155	cell adhesion
0.51	GO:0006357	regulation of transcription by RNA polymerase II

0.51

GO:0003676

nucleic acid binding

0.57	GO:0000792	heterochromatin
0.46	GO:0005634	nucleus

sp|O61365|NACH_DROME
Sodium channel protein Nach
Search

0.44	Sodium channel protein Nach

0.77	GO:0035725	sodium ion transmembrane transport
0.55	GO:0035002	liquid clearance, open tracheal system
0.43	GO:0008049	male courtship behavior
0.42	GO:0019236	response to pheromone

0.81

GO:0005272

sodium channel activity

0.30

GO:0031224

intrinsic component of membrane

sp|O61366|GPRS_DROME
Serine-enriched protein
Search

0.66	serine-enriched protein isoform X3

0.46

GO:0005975

carbohydrate metabolic process

0.57	GO:0103025	alpha-amylase activity (releasing maltohexaose)
0.57	GO:0004556	alpha-amylase activity
0.42	GO:0043169	cation binding

0.30

GO:0044425

membrane part

0.57

GO:0004556

sp|O61443|MK14B_DROME
Mitogen-activated protein kinase 14B
Search

0.58	Mitogen-activated protein kinase

0.80	GO:0000165	MAPK cascade
0.54	GO:0048082	regulation of adult chitin-containing cuticle pigmentation
0.54	GO:0038001	paracrine signaling
0.53	GO:0071243	cellular response to arsenic-containing substance
0.52	GO:0045793	positive regulation of cell size
0.52	GO:0071276	cellular response to cadmium ion
0.51	GO:1900407	regulation of cellular response to oxidative stress
0.51	GO:0008340	determination of adult lifespan
0.51	GO:0042542	response to hydrogen peroxide
0.50	GO:0050832	defense response to fungus

0.82	GO:0004707	MAP kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle

0.82	EC:2.7.11.24	GO:0004707
0.82	KEGG:R00162	GO:0004707

tr|O61444|O61444_DROME
MAP kinase kinase 4, isoform A
Search

0.76	Dual specificity mitogen-activated protein kinase kinase

0.63	GO:0006468	protein phosphorylation
0.51	GO:0048082	regulation of adult chitin-containing cuticle pigmentation
0.51	GO:0031098	stress-activated protein kinase signaling cascade
0.50	GO:0043507	positive regulation of JUN kinase activity
0.50	GO:0032147	activation of protein kinase activity
0.46	GO:0048666	neuron development
0.45	GO:2000672	negative regulation of motor neuron apoptotic process
0.44	GO:0071260	cellular response to mechanical stimulus
0.44	GO:0034393	positive regulation of smooth muscle cell apoptotic process
0.41	GO:0009611	response to wounding

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0004708	MAP kinase kinase activity
0.38	GO:0005057	signal transducer activity, downstream of receptor
0.36	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.34	GO:0004713	protein tyrosine kinase activity

0.48	GO:0030424	axon
0.37	GO:0005622	intracellular
0.36	GO:0043204	perikaryon
0.35	GO:0030425	dendrite
0.33	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.68

GO:0004674

sp|O61491|FLOT1_DROME
Flotillin-1
Search

0.71	Flotillin-1

0.51	GO:0006629	lipid metabolic process
0.45	GO:0055114	oxidation-reduction process
0.44	GO:0007275	multicellular organism development
0.42	GO:0045454	cell redox homeostasis
0.42	GO:0055085	transmembrane transport
0.41	GO:0032259	methylation

0.54	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.47	GO:0016972	thiol oxidase activity
0.43	GO:0022857	transmembrane transporter activity
0.41	GO:0005198	structural molecule activity
0.41	GO:0008168	methyltransferase activity

0.52	GO:0016600	flotillin complex
0.46	GO:0005737	cytoplasm
0.45	GO:0019866	organelle inner membrane
0.42	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.54

EC:1.3

GO:0016627

sp|O61492|FLOT2_DROME
Flotillin-2
Search

0.50

Flotillin

0.57	GO:0061357	positive regulation of Wnt protein secretion
0.57	GO:0035011	melanotic encapsulation of foreign target
0.54	GO:0007155	cell adhesion
0.43	GO:0055114	oxidation-reduction process

0.51	GO:0050660	flavin adenine dinucleotide binding
0.50	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.44	GO:0005198	structural molecule activity
0.41	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.40	GO:0140101	catalytic activity, acting on a tRNA

0.57	GO:0016600	flotillin complex
0.48	GO:0030139	endocytic vesicle
0.47	GO:0005829	cytosol
0.46	GO:0005768	endosome
0.30	GO:0016021	integral component of membrane

0.50

EC:1.1

GO:0016614

sp|O61613|NMT_DROME
Glycylpeptide N-tetradecanoyltransferase
Search

0.73	Glycylpeptide N-tetradecanoyltransferase

0.85	GO:0006499	N-terminal protein myristoylation
0.49	GO:0018201	peptidyl-glycine modification
0.36	GO:0007391	dorsal closure
0.34	GO:0006177	GMP biosynthetic process
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression

0.85	GO:0004379	glycylpeptide N-tetradecanoyltransferase activity
0.35	GO:0008080	N-acetyltransferase activity
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.34	GO:0000062	fatty-acyl-CoA binding
0.34	GO:0008097	5S rRNA binding
0.34	GO:0003922	GMP synthase (glutamine-hydrolyzing) activity
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0019898	extrinsic component of membrane
0.41	GO:0005794	Golgi apparatus
0.40	GO:0005829	cytosol
0.37	GO:0005886	plasma membrane
0.33	GO:0005840	ribosome
0.33	GO:0005739	mitochondrion

0.85

EC:2.3.1.97

GO:0004379

sp|O61643|INHB_DROME
Inhibin beta chain
Search

0.72	LOW QUALITY PROTEIN: inhibin beta chain

0.76	GO:0010469	regulation of receptor activity
0.52	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.52	GO:0060395	SMAD protein signal transduction
0.48	GO:0043408	regulation of MAPK cascade
0.46	GO:0048699	generation of neurons
0.45	GO:0032332	positive regulation of chondrocyte differentiation
0.45	GO:0060389	pathway-restricted SMAD protein phosphorylation
0.45	GO:0048468	cell development
0.45	GO:0032924	activin receptor signaling pathway
0.45	GO:0030509	BMP signaling pathway

0.78	GO:0008083	growth factor activity
0.49	GO:0005160	transforming growth factor beta receptor binding
0.47	GO:0005125	cytokine activity
0.40	GO:0042803	protein homodimerization activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.33	GO:0005750	mitochondrial respiratory chain complex III
0.30	GO:0016021	integral component of membrane

sp|O61661|CHK1_DROME
Serine/threonine-protein kinase grp
Search

0.48	Non-specific serine/threonine protein kinase

0.74	GO:0000077	DNA damage checkpoint
0.63	GO:0006468	protein phosphorylation
0.54	GO:0007348	regulation of syncytial blastoderm mitotic cell cycle
0.54	GO:1902750	negative regulation of cell cycle G2/M phase transition
0.53	GO:0044774	mitotic DNA integrity checkpoint
0.52	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.52	GO:0051299	centrosome separation
0.51	GO:1901991	negative regulation of mitotic cell cycle phase transition
0.51	GO:0000076	DNA replication checkpoint
0.50	GO:0007050	cell cycle arrest

0.66	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0035173	histone kinase activity

0.44	GO:0005634	nucleus
0.37	GO:0000785	chromatin
0.37	GO:0005657	replication fork
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:0005813	centrosome
0.35	GO:0000793	condensed chromosome
0.35	GO:0005829	cytosol

0.66

GO:0004674

tr|O61722|O61722_DROME
PRL-1 phosphatase, isoform A
Search

0.40	Tyrosine phosphatase type IVA

0.71	GO:0006470	protein dephosphorylation
0.43	GO:0043542	endothelial cell migration
0.42	GO:1901224	positive regulation of NIK/NF-kappaB signaling
0.41	GO:1904951	positive regulation of establishment of protein localization
0.40	GO:0043117	positive regulation of vascular permeability
0.40	GO:1900746	regulation of vascular endothelial growth factor signaling pathway
0.39	GO:1990830	cellular response to leukemia inhibitory factor
0.38	GO:0007219	Notch signaling pathway
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.77	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.42	GO:0004725	protein tyrosine phosphatase activity

0.39	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.37	GO:0005886	plasma membrane
0.33	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system
0.30	GO:0016021	integral component of membrane

0.77

GO:0008138

sp|O61734|CYCL_DROME
Protein cycle
Search

0.78	Circadian transcription modulator

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0003053	circadian regulation of heart rate
0.48	GO:0045187	regulation of circadian sleep/wake cycle, sleep
0.45	GO:0042594	response to starvation
0.40	GO:0009648	photoperiodism
0.38	GO:0010604	positive regulation of macromolecule metabolic process
0.37	GO:0008062	eclosion rhythm

0.68	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.45	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.38	GO:0003682	chromatin binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.37	GO:0000785	chromatin
0.34	GO:0031974	membrane-enclosed lumen
0.30	GO:0016020	membrane

sp|O61735|CLOCK_DROME
Circadian locomoter output cycles protein kaput
Search

0.57	Circadian locomoter output cycles protein kaput

0.62	GO:0003053	circadian regulation of heart rate
0.58	GO:0045187	regulation of circadian sleep/wake cycle, sleep
0.58	GO:0009649	entrainment of circadian clock
0.58	GO:0045475	locomotor rhythm
0.57	GO:0032922	circadian regulation of gene expression
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.53	GO:0043066	negative regulation of apoptotic process
0.52	GO:0009266	response to temperature stimulus

0.68	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.53	GO:0003682	chromatin binding
0.51	GO:0008134	transcription factor binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part

tr|O62526|O62526_DROME
ADP/ATP translocase
Search

0.56	Adenine nucleotide translocase

0.55	GO:0055085	transmembrane transport
0.39	GO:0031532	actin cytoskeleton reorganization
0.39	GO:0006839	mitochondrial transport
0.38	GO:0007155	cell adhesion
0.36	GO:0015866	ADP transport
0.35	GO:0007005	mitochondrion organization
0.35	GO:0090559	regulation of membrane permeability
0.35	GO:0015867	ATP transport
0.35	GO:0060546	negative regulation of necroptotic process
0.34	GO:0006915	apoptotic process

0.57	GO:0022857	transmembrane transporter activity
0.39	GO:0003779	actin binding
0.33	GO:0008233	peptidase activity

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.34	GO:0043209	myelin sheath
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008233

tr|O62530|O62530_DROME
Adaptor protein complex 2, mu subunit, isoform A
Search

0.78	Clathrin coat associated protein ap-50

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.43	GO:0033227	dsRNA transport
0.41	GO:0098657	import into cell
0.35	GO:1900244	positive regulation of synaptic vesicle endocytosis
0.34	GO:0002092	positive regulation of receptor internalization
0.34	GO:0036465	synaptic vesicle recycling
0.34	GO:0097480	establishment of synaptic vesicle localization
0.34	GO:0006915	apoptotic process
0.34	GO:0016050	vesicle organization

0.70	GO:0008289	lipid binding
0.40	GO:0097718	disordered domain specific binding
0.39	GO:0008565	protein transporter activity
0.34	GO:0050750	low-density lipoprotein particle receptor binding
0.34	GO:0005048	signal sequence binding
0.33	GO:0020037	heme binding
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0046872	metal ion binding

0.79	GO:0030131	clathrin adaptor complex
0.43	GO:0005905	clathrin-coated pit
0.43	GO:0030128	clathrin coat of endocytic vesicle
0.39	GO:0098797	plasma membrane protein complex
0.36	GO:0005739	mitochondrion
0.34	GO:0043195	terminal bouton

0.32

GO:0016491

tr|O62531|O62531_DROME
Adaptor protein complex 1, mu subunit
Search

0.75	Clathrin coat assembly protein ap-1

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.44	GO:0016050	vesicle organization
0.44	GO:0035646	endosome to melanosome transport
0.43	GO:2001136	negative regulation of endocytic recycling
0.41	GO:0045746	negative regulation of Notch signaling pathway
0.40	GO:0048749	compound eye development
0.39	GO:0010256	endomembrane system organization
0.34	GO:0048565	digestive tract development
0.34	GO:0007420	brain development

0.38	GO:0008565	protein transporter activity
0.34	GO:0030276	clathrin binding
0.33	GO:0003887	DNA-directed DNA polymerase activity
0.33	GO:0003676	nucleic acid binding

0.79	GO:0030131	clathrin adaptor complex
0.42	GO:0035976	transcription factor AP-1 complex
0.41	GO:0030665	clathrin-coated vesicle membrane
0.40	GO:0030140	trans-Golgi network transport vesicle
0.39	GO:0030658	transport vesicle membrane
0.39	GO:0030120	vesicle coat
0.39	GO:0030660	Golgi-associated vesicle membrane
0.39	GO:0005794	Golgi apparatus
0.34	GO:0005760	gamma DNA polymerase complex
0.34	GO:0070062	extracellular exosome

0.33

GO:0003887

sp|O62589|GD_DROME
Serine protease gd
Search

0.65	Serine protease gd

0.68	GO:0007370	ventral furrow formation
0.66	GO:0008063	Toll signaling pathway
0.66	GO:0009950	dorsal/ventral axis specification
0.60	GO:0006508	proteolysis
0.56	GO:0051604	protein maturation
0.42	GO:0007309	oocyte axis specification
0.35	GO:0006956	complement activation
0.33	GO:0009620	response to fungus
0.32	GO:0009617	response to bacterium
0.32	GO:0006898	receptor-mediated endocytosis

0.68	GO:0004252	serine-type endopeptidase activity
0.33	GO:0005044	scavenger receptor activity
0.32	GO:0005509	calcium ion binding

0.38	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.68

GO:0004252

tr|O62602|O62602_DROME
Licorne
Search

0.46	Dual specificity mitogen-activated protein kinase kinase

0.63	GO:0006468	protein phosphorylation
0.50	GO:0048082	regulation of adult chitin-containing cuticle pigmentation
0.49	GO:0002385	mucosal immune response
0.49	GO:0045793	positive regulation of cell size
0.49	GO:0040018	positive regulation of multicellular organism growth
0.49	GO:0007309	oocyte axis specification
0.48	GO:0032147	activation of protein kinase activity
0.47	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.47	GO:0043406	positive regulation of MAP kinase activity
0.42	GO:0035556	intracellular signal transduction

0.64	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.49	GO:0004708	MAP kinase kinase activity
0.37	GO:0005057	signal transducer activity, downstream of receptor

0.36	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.64

GO:0004674

tr|O62609|O62609_DROME
Mothers against decapentaplegic homolog
Search

0.55	Mothers against decapentaplegic homolog

0.81	GO:0007179	transforming growth factor beta receptor signaling pathway
0.63	GO:0045887	positive regulation of synaptic growth at neuromuscular junction
0.62	GO:0042078	germ-line stem cell division
0.62	GO:0007480	imaginal disc-derived leg morphogenesis
0.62	GO:0031290	retinal ganglion cell axon guidance
0.62	GO:0030718	germ-line stem cell population maintenance
0.61	GO:0035019	somatic stem cell population maintenance
0.61	GO:0009950	dorsal/ventral axis specification
0.60	GO:0007476	imaginal disc-derived wing morphogenesis
0.60	GO:0030707	ovarian follicle cell development

0.60	GO:0003700	DNA binding transcription factor activity
0.55	GO:0030616	transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
0.52	GO:0003677	DNA binding
0.43	GO:0005515	protein binding

0.73	GO:0005667	transcription factor complex
0.60	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|O62618|MK14A_DROME
Mitogen-activated protein kinase 14A
Search

0.58	Mitogen-activated protein kinase

0.79	GO:0000165	MAPK cascade
0.54	GO:0048082	regulation of adult chitin-containing cuticle pigmentation
0.54	GO:0038001	paracrine signaling
0.53	GO:0071243	cellular response to arsenic-containing substance
0.53	GO:0045793	positive regulation of cell size
0.52	GO:0071276	cellular response to cadmium ion
0.51	GO:1900407	regulation of cellular response to oxidative stress
0.51	GO:0008340	determination of adult lifespan
0.51	GO:0042542	response to hydrogen peroxide
0.50	GO:0050832	defense response to fungus

0.81	GO:0004707	MAP kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0017154	semaphorin receptor activity

0.45	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.81	EC:2.7.11.24	GO:0004707
0.81	KEGG:R00162	GO:0004707

sp|O62619|KPYK_DROME
Pyruvate kinase
Search

0.47	Pyruvate kinase

0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.46	GO:0007525	somatic muscle development
0.46	GO:0009744	response to sucrose
0.46	GO:0007520	myoblast fusion
0.44	GO:0042593	glucose homeostasis
0.33	GO:0031167	rRNA methylation

0.78	GO:0004743	pyruvate kinase activity
0.77	GO:0030955	potassium ion binding
0.64	GO:0000287	magnesium ion binding
0.60	GO:0016301	kinase activity
0.34	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.46	GO:0043186	P granule
0.41	GO:0005829	cytosol

0.78

EC:2.7.1.40

GO:0004743

sp|O62621|COPB2_DROME
Coatomer subunit beta'
Search

0.44	Coatomer subunit beta'

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.46	GO:0010883	regulation of lipid storage
0.44	GO:0030903	notochord development
0.44	GO:0061053	somite development
0.38	GO:1901998	toxin transport
0.34	GO:0009966	regulation of signal transduction
0.34	GO:0006470	protein dephosphorylation
0.33	GO:0010951	negative regulation of endopeptidase activity

0.62	GO:0005198	structural molecule activity
0.34	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0016740	transferase activity

0.75	GO:0030117	membrane coat
0.74	GO:0030663	COPI-coated vesicle membrane
0.68	GO:0000139	Golgi membrane
0.44	GO:0005795	Golgi stack
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0004721

sp|O76206|RIFK_DROME
Putative riboflavin kinase
Search

RFK

0.63	Riboflavin kinase

0.73	GO:0006771	riboflavin metabolic process
0.73	GO:0042727	flavin-containing compound biosynthetic process
0.67	GO:0042364	water-soluble vitamin biosynthetic process
0.57	GO:0016310	phosphorylation
0.47	GO:0033864	positive regulation of NAD(P)H oxidase activity
0.44	GO:0046444	FMN metabolic process
0.42	GO:0006915	apoptotic process
0.41	GO:0072593	reactive oxygen species metabolic process
0.40	GO:0009156	ribonucleoside monophosphate biosynthetic process
0.40	GO:0009260	ribonucleotide biosynthetic process

0.79	GO:0008531	riboflavin kinase activity
0.35	GO:0046872	metal ion binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0005515	protein binding
0.32	GO:0008897	holo-[acyl-carrier-protein] synthase activity
0.32	GO:0016787	hydrolase activity
0.32	GO:0005215	transporter activity

0.41	GO:0005739	mitochondrion
0.38	GO:0019866	organelle inner membrane
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:2.7.1.26	GO:0008531
0.79	KEGG:R00549	GO:0008531

sp|O76324|DCO_DROME
Discs overgrown protein kinase
Search

0.79	Discs overgrown protein kinase

0.63	GO:0006468	protein phosphorylation
0.52	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.52	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.52	GO:0042752	regulation of circadian rhythm
0.51	GO:0007623	circadian rhythm
0.49	GO:0007555	regulation of ecdysteroid secretion
0.49	GO:0120036	plasma membrane bounded cell projection organization
0.48	GO:0007446	imaginal disc growth
0.48	GO:0018209	peptidyl-serine modification
0.47	GO:0048148	behavioral response to cocaine

0.65	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.44	GO:0045296	cadherin binding
0.40	GO:0050321	tau-protein kinase activity
0.36	GO:0042277	peptide binding

0.45	GO:0005876	spindle microtubule
0.44	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005634	nucleus
0.43	GO:0005813	centrosome
0.42	GO:0005794	Golgi apparatus
0.40	GO:0005886	plasma membrane
0.36	GO:0043005	neuron projection
0.36	GO:0005829	cytosol
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:0098588	bounding membrane of organelle

0.65

GO:0004674

tr|O76339|O76339_DROME
AT04446p
Search

0.40	Methylated-DNA--protein-cysteine methyltransferase AdaB

0.65	GO:0006281	DNA repair
0.63	GO:0032259	methylation
0.53	GO:0035510	DNA dealkylation
0.39	GO:0006351	transcription, DNA-templated
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression

0.78	GO:0003908	methylated-DNA-[protein]-cysteine S-methyltransferase activity
0.42	GO:0043565	sequence-specific DNA binding
0.41	GO:0003700	DNA binding transcription factor activity
0.40	GO:0008270	zinc ion binding

0.35	GO:0005737	cytoplasm
0.35	GO:0005634	nucleus

0.78

EC:2.1.1.63

GO:0003908

sp|O76454|PHS_DROME
Pterin-4-alpha-carbinolamine dehydratase
Search

0.55	Pterin-4-alpha-carbinolamine dehydratase

0.80	GO:0046146	tetrahydrobiopterin metabolic process
0.80	GO:0034312	diol biosynthetic process
0.72	GO:0042559	pteridine-containing compound biosynthetic process
0.65	GO:0009108	coenzyme biosynthetic process
0.47	GO:0051291	protein heterooligomerization
0.47	GO:0051289	protein homotetramerization
0.37	GO:0055114	oxidation-reduction process
0.37	GO:0043496	regulation of protein homodimerization activity
0.36	GO:0045893	positive regulation of transcription, DNA-templated
0.35	GO:0006558	L-phenylalanine metabolic process

0.81	GO:0008124	4-alpha-hydroxytetrahydrobiopterin dehydratase activity
0.47	GO:0004505	phenylalanine 4-monooxygenase activity
0.43	GO:0042802	identical protein binding
0.36	GO:0003713	transcription coactivator activity
0.35	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0046983	protein dimerization activity
0.32	GO:0003677	DNA binding

0.42	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol
0.35	GO:0070062	extracellular exosome
0.32	GO:0005739	mitochondrion

0.81	EC:4.2.1.96	GO:0008124
0.81	KEGG:R04734	GO:0008124

sp|O76460|RAD54_DROME
DNA repair and recombination protein RAD54-like
Search

0.75	DNA repair and recombination protein RAD54

0.55	GO:0010212	response to ionizing radiation
0.52	GO:0000724	double-strand break repair via homologous recombination
0.50	GO:0000733	DNA strand renaturation
0.50	GO:0000711	meiotic DNA repair synthesis
0.50	GO:0030716	oocyte fate determination
0.48	GO:0008340	determination of adult lifespan
0.47	GO:0007131	reciprocal meiotic recombination
0.47	GO:0048477	oogenesis
0.46	GO:0006338	chromatin remodeling
0.43	GO:0042493	response to drug

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0036310	annealing helicase activity
0.42	GO:0004386	helicase activity
0.38	GO:0003677	DNA binding
0.38	GO:0008094	DNA-dependent ATPase activity
0.34	GO:0004826	phenylalanine-tRNA ligase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.45	GO:0005634	nucleus
0.43	GO:0043233	organelle lumen
0.40	GO:0043234	protein complex
0.40	GO:0044446	intracellular organelle part

0.34

EC:6.1.1.20

GO:0004826

tr|O76462|O76462_DROME
Bem46
Search

0.67	Hydrolase activity

0.32

GO:0006508

proteolysis

0.41	GO:0016787	hydrolase activity
0.33	GO:0140101	catalytic activity, acting on a tRNA
0.32	GO:0140096	catalytic activity, acting on a protein

0.30

GO:0031224

intrinsic component of membrane

0.41

GO:0016787

sp|O76464|NFT1_DROME
Nitrilase and fragile histidine triad fusion protein NitFhit
Search

0.38	Nitrilase and fragile histidine triad fusion protein NitFhit

0.45	GO:0006807	nitrogen compound metabolic process
0.37	GO:0046483	heterocycle metabolic process
0.37	GO:1901360	organic cyclic compound metabolic process
0.37	GO:0006725	cellular aromatic compound metabolic process
0.35	GO:0046686	response to cadmium ion
0.30	GO:0044238	primary metabolic process

0.53	GO:0047710	bis(5'-adenosyl)-triphosphatase activity
0.38	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
0.37	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0000166	nucleotide binding

0.33

GO:0009536

plastid

0.53	EC:3.6.1.29	GO:0047710
0.53	KEGG:R00187	GO:0047710

sp|O76511|TYSY_DROME
Thymidylate synthase
Search

0.41	Bifunctional dihydrofolate reductase-thymidylate synthase

0.78	GO:0006231	dTMP biosynthetic process
0.63	GO:0032259	methylation
0.49	GO:0046654	tetrahydrofolate biosynthetic process
0.48	GO:0006730	one-carbon metabolic process
0.40	GO:0055114	oxidation-reduction process
0.36	GO:0006235	dTTP biosynthetic process
0.34	GO:0009256	10-formyltetrahydrofolate metabolic process
0.34	GO:0043086	negative regulation of catalytic activity
0.34	GO:0009966	regulation of signal transduction
0.34	GO:0060041	retina development in camera-type eye

0.80	GO:0004799	thymidylate synthase activity
0.51	GO:0004146	dihydrofolate reductase activity
0.35	GO:0019212	phosphatase inhibitor activity
0.35	GO:0004633	phosphopantothenoylcysteine decarboxylase activity
0.34	GO:0010181	FMN binding
0.33	GO:0016763	transferase activity, transferring pentosyl groups

0.38	GO:0034399	nuclear periphery
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.80	EC:2.1.1.45	GO:0004799
0.80	KEGG:R02101	GO:0004799

tr|O76513|O76513_DROME
Cyclin H
Search

0.77	CDK activating kinase

0.75	GO:0045859	regulation of protein kinase activity
0.57	GO:0006351	transcription, DNA-templated
0.47	GO:0051726	regulation of cell cycle
0.45	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain
0.44	GO:0045944	positive regulation of transcription by RNA polymerase II
0.44	GO:0006468	protein phosphorylation
0.43	GO:0050821	protein stabilization
0.42	GO:0033674	positive regulation of kinase activity
0.35	GO:0007049	cell cycle
0.34	GO:0006294	nucleotide-excision repair, preincision complex assembly

0.81	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.52	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.48	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.40	GO:0008094	DNA-dependent ATPase activity
0.36	GO:0000990	transcription factor activity, core RNA polymerase binding
0.34	GO:0005179	hormone activity
0.33	GO:0003676	nucleic acid binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.84	GO:0070985	TFIIK complex
0.47	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.44	GO:0150005	enzyme activator complex
0.33	GO:0005576	extracellular region
0.33	GO:0016592	mediator complex
0.30	GO:0016020	membrane

0.81

GO:0016538

tr|O76521|O76521_DROME
Importin subunit alpha
Search

0.61	Importin subunit alpha

0.80	GO:0006606	protein import into nucleus
0.49	GO:0007283	spermatogenesis
0.36	GO:0045454	cell redox homeostasis
0.36	GO:0098926	postsynaptic signal transduction
0.35	GO:0006309	apoptotic DNA fragmentation
0.34	GO:0000018	regulation of DNA recombination
0.34	GO:0055114	oxidation-reduction process
0.34	GO:0075733	intracellular transport of virus
0.34	GO:0044068	modulation by symbiont of host cellular process
0.33	GO:0019048	modulation by virus of host morphology or physiology

0.83	GO:0061608	nuclear import signal receptor activity
0.68	GO:0008565	protein transporter activity
0.46	GO:0008139	nuclear localization sequence binding
0.35	GO:0005094	Rho GDP-dissociation inhibitor activity
0.34	GO:0103025	alpha-amylase activity (releasing maltohexaose)
0.34	GO:0004556	alpha-amylase activity
0.34	GO:0005515	protein binding
0.34	GO:0016491	oxidoreductase activity
0.34	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.33	GO:0003924	GTPase activity

0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.41	GO:0012505	endomembrane system
0.39	GO:0031975	envelope
0.39	GO:0030425	dendrite
0.38	GO:0043234	protein complex
0.33	GO:0044216	other organism cell
0.33	GO:0018995	host

0.34

GO:0004556

tr|O76742|O76742_DROME
CG5915 protein
Search

RAB7A

0.64	CCAP receptor

0.48	GO:0061883	clathrin-dependent endocytosis involved in vitellogenesis
0.47	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway
0.47	GO:1990182	exosomal secretion
0.46	GO:0044130	negative regulation of growth of symbiont in host
0.46	GO:0048190	wing disc dorsal/ventral pattern formation
0.46	GO:0033227	dsRNA transport
0.45	GO:0007298	border follicle cell migration
0.45	GO:0008593	regulation of Notch signaling pathway
0.36	GO:0061191	positive regulation of vacuole fusion, non-autophagic
0.36	GO:0000011	vacuole inheritance

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0032403	protein complex binding

0.45	GO:0031902	late endosome membrane
0.43	GO:0005938	cell cortex
0.37	GO:0070062	extracellular exosome
0.36	GO:1990816	vacuole-mitochondrion membrane contact site
0.35	GO:0030906	retromer, cargo-selective complex
0.35	GO:0000329	fungal-type vacuole membrane
0.35	GO:0043025	neuronal cell body
0.34	GO:0045202	synapse
0.34	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane

tr|O76752|O76752_DROME
CG12117-PA
Search

0.42	Sepiapterin reductase

0.79	GO:0046146	tetrahydrobiopterin metabolic process
0.79	GO:0034312	diol biosynthetic process
0.71	GO:0042559	pteridine-containing compound biosynthetic process
0.64	GO:0009108	coenzyme biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.37	GO:0006633	fatty acid biosynthetic process

0.86	GO:0004757	sepiapterin reductase activity
0.39	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
0.37	GO:0051287	NAD binding
0.36	GO:0102131	3-oxo-glutaryl-[acp] methyl ester reductase activity
0.36	GO:0102132	3-oxo-pimeloyl-[acp] methyl ester reductase activity

0.30

GO:0031224

intrinsic component of membrane

0.86

EC:1.1.1.153

GO:0004757

sp|O76767|ERD2_DROME
ER lumen protein-retaining receptor
Search

0.67	ER lumen protein-retaining receptor

0.84	GO:0006621	protein retention in ER lumen
0.65	GO:0015031	protein transport
0.33	GO:0016192	vesicle-mediated transport

0.84	GO:0046923	ER retention sequence binding
0.32	GO:0003676	nucleic acid binding

0.71	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

tr|O76857|O76857_DROME
BCL7-like
Search

BCL7A

0.80	B-cell CLL/lymphoma 7 protein family member B-B

0.47

GO:0045892

negative regulation of transcription, DNA-templated

0.43

GO:0005515

protein binding

tr|O76861|O76861_DROME
CG2685
Search

WBP11

0.75	WW domain-binding protein 11

0.63	GO:0006396	RNA processing
0.39	GO:0016071	mRNA metabolic process
0.33	GO:0016072	rRNA metabolic process
0.32	GO:0042254	ribosome biogenesis
0.32	GO:0030001	metal ion transport
0.32	GO:0055085	transmembrane transport

0.36	GO:0003723	RNA binding
0.35	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.32	GO:0046873	metal ion transmembrane transporter activity

0.40	GO:0005681	spliceosomal complex
0.36	GO:1902494	catalytic complex
0.31	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.35

EC:2.4.2.30

GO:0003950

tr|O76863|O76863_DROME
EG:100G10.3 protein
Search

EIF2B2

0.61	Translation initiation factor

0.59	GO:0006413	translational initiation
0.49	GO:0071456	cellular response to hypoxia
0.41	GO:1904628	cellular response to phorbol 13-acetate 12-myristate
0.40	GO:0014003	oligodendrocyte development
0.40	GO:0001541	ovarian follicle development
0.40	GO:0042552	myelination
0.37	GO:0065009	regulation of molecular function
0.36	GO:0006355	regulation of transcription, DNA-templated
0.34	GO:0006511	ubiquitin-dependent protein catabolic process
0.34	GO:0016567	protein ubiquitination

0.59	GO:0003743	translation initiation factor activity
0.39	GO:0005085	guanyl-nucleotide exchange factor activity
0.37	GO:0032550	purine ribonucleoside binding
0.37	GO:0032561	guanyl ribonucleotide binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.33	GO:0008270	zinc ion binding

0.42	GO:0005851	eukaryotic translation initiation factor 2B complex
0.34	GO:0005829	cytosol
0.33	GO:0005634	nucleus

tr|O76865|O76865_DROME
Csat, isoform B
Search

0.43	UDP-N-acetylgalactosamine transmembrane transporter

0.69	GO:0008643	carbohydrate transport
0.63	GO:1902600	hydrogen ion transmembrane transport
0.50	GO:0090481	pyrimidine nucleotide-sugar transmembrane transport
0.43	GO:0098656	anion transmembrane transport
0.43	GO:0015711	organic anion transport

0.79	GO:0005351	sugar:proton symporter activity
0.50	GO:0005463	UDP-N-acetylgalactosamine transmembrane transporter activity
0.48	GO:0005459	UDP-galactose transmembrane transporter activity
0.39	GO:0005456	CMP-N-acetylneuraminate transmembrane transporter activity
0.39	GO:0005461	UDP-glucuronic acid transmembrane transporter activity
0.39	GO:0005464	UDP-xylose transmembrane transporter activity

0.74	GO:0000139	Golgi membrane
0.47	GO:0005797	Golgi medial cisterna
0.33	GO:0005783	endoplasmic reticulum
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|O76870|O76870_DROME
EG:100G7.5 protein
Search

0.30

GO:0044425

membrane part

tr|O76874|O76874_DROME
CG3777, isoform A
Search

0.55	GO:0006508	proteolysis
0.45	GO:0035725	sodium ion transmembrane transport
0.37	GO:0006030	chitin metabolic process
0.36	GO:0007155	cell adhesion
0.36	GO:0006468	protein phosphorylation
0.35	GO:0000272	polysaccharide catabolic process
0.35	GO:2000142	regulation of DNA-templated transcription, initiation
0.35	GO:0006352	DNA-templated transcription, initiation

0.61	GO:0004252	serine-type endopeptidase activity
0.46	GO:0005272	sodium channel activity
0.37	GO:0004674	protein serine/threonine kinase activity
0.37	GO:0008061	chitin binding
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.36	GO:0005509	calcium ion binding
0.35	GO:0004222	metalloendopeptidase activity
0.35	GO:0000996	promoter selection factor activity
0.35	GO:0008270	zinc ion binding
0.34	GO:0032559	adenyl ribonucleotide binding

0.41	GO:0005576	extracellular region
0.36	GO:0005618	cell wall
0.30	GO:0031224	intrinsic component of membrane

0.61

GO:0004252

tr|O76876|O76876_DROME
EG:132E8.1 protein
Search

0.73	GO:0000380	alternative mRNA splicing, via spliceosome
0.70	GO:0007530	sex determination
0.43	GO:0042742	defense response to bacterium
0.36	GO:0007548	sex differentiation
0.35	GO:0006261	DNA-dependent DNA replication
0.35	GO:0007446	imaginal disc growth
0.35	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.35	GO:0007549	dosage compensation
0.35	GO:0030154	cell differentiation
0.35	GO:0071897	DNA biosynthetic process

0.59	GO:0003723	RNA binding
0.35	GO:0003887	DNA-directed DNA polymerase activity
0.35	GO:0000900	translation repressor activity, nucleic acid binding
0.34	GO:0008168	methyltransferase activity
0.33	GO:0005515	protein binding
0.33	GO:0003677	DNA binding
0.32	GO:0008409	5'-3' exonuclease activity

0.34	GO:0005634	nucleus
0.33	GO:0043234	protein complex
0.32	GO:0005762	mitochondrial large ribosomal subunit
0.30	GO:0016020	membrane

0.35

GO:0003887

tr|O76877|O76877_DROME
CG3719
Search

0.41	thioredoxin, mitochondrial

0.69	GO:0045454	cell redox homeostasis
0.66	GO:0006662	glycerol ether metabolic process
0.48	GO:0055114	oxidation-reduction process
0.33	GO:0007165	signal transduction

0.63	GO:0015035	protein disulfide oxidoreductase activity
0.32	GO:0016853	isomerase activity

0.34	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.32

GO:0016853

sp|O76878|RIPL_DROME
RILP-like protein homolog
Search

LOC108097118

0.94	JNK SAPK-associated protein-1

0.43

GO:0060271

cilium assembly

0.60	GO:0046983	protein dimerization activity
0.45	GO:0051959	dynein light intermediate chain binding
0.42	GO:0031267	small GTPase binding

0.44	GO:0036064	ciliary basal body
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|O76879|CCCP_DROME
Circadian clock-controlled protein
Search

0.57	Circadian clock-controlled protein

0.82	GO:0007623	circadian rhythm
0.46	GO:0032504	multicellular organism reproduction

0.45

GO:0005615

extracellular space

tr|O76888|O76888_DROME
Uncharacterized protein
Search

0.40	Cysteine-rich protein 2-binding protein

0.43	GO:0032012	regulation of ARF protein signal transduction
0.40	GO:0006457	protein folding
0.39	GO:0065009	regulation of molecular function
0.39	GO:0006281	DNA repair
0.39	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.38	GO:0006629	lipid metabolic process

0.43	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.42	GO:0031072	heat shock protein binding
0.41	GO:0003684	damaged DNA binding
0.41	GO:0051082	unfolded protein binding
0.39	GO:0004519	endonuclease activity
0.36	GO:0046872	metal ion binding

0.38	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|O76892|O76892_DROME
EG:4F1.1 protein
Search

SGCD

0.89	Sarcoglycan, delta (Dystrophin-associated glycoprotein)

0.54	GO:0060047	heart contraction
0.52	GO:0061061	muscle structure development
0.50	GO:0009888	tissue development
0.49	GO:0048468	cell development
0.48	GO:0031032	actomyosin structure organization
0.48	GO:0010927	cellular component assembly involved in morphogenesis
0.45	GO:0097435	supramolecular fiber organization
0.45	GO:0007507	heart development
0.44	GO:0070925	organelle assembly
0.41	GO:0048798	swim bladder inflation

0.37	GO:0008307	structural constituent of muscle
0.32	GO:0005515	protein binding
0.30	GO:0003824	catalytic activity

0.85	GO:0016012	sarcoglycan complex
0.50	GO:0043034	costamere
0.48	GO:0042383	sarcolemma
0.36	GO:0005654	nucleoplasm
0.34	GO:0005856	cytoskeleton
0.33	GO:0005887	integral component of plasma membrane

tr|O76894|O76894_DROME
EG:56G7.1 protein
Search

0.72	GO:0006030	chitin metabolic process
0.35	GO:0006468	protein phosphorylation
0.34	GO:0007162	negative regulation of cell adhesion
0.34	GO:0007155	cell adhesion
0.34	GO:0010951	negative regulation of endopeptidase activity
0.34	GO:0006898	receptor-mediated endocytosis
0.34	GO:0009405	pathogenesis
0.33	GO:0006950	response to stress
0.33	GO:0006508	proteolysis
0.33	GO:0055114	oxidation-reduction process

0.71	GO:0008061	chitin binding
0.56	GO:0005201	extracellular matrix structural constituent
0.35	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.35	GO:0016301	kinase activity
0.35	GO:0005518	collagen binding
0.34	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.34	GO:0005044	scavenger receptor activity
0.34	GO:0001871	pattern binding
0.34	GO:0032559	adenyl ribonucleotide binding

0.67	GO:0042600	chorion
0.63	GO:0005576	extracellular region
0.34	GO:0046658	anchored component of plasma membrane
0.34	GO:0005618	cell wall
0.33	GO:0005669	transcription factor TFIID complex
0.33	GO:0055044	symplast
0.33	GO:0005911	cell-cell junction
0.31	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.35

GO:0016773

tr|O76895|O76895_DROME
Arginase
Search

0.59

Arginase

0.71	GO:0000050	urea cycle
0.71	GO:0006525	arginine metabolic process
0.55	GO:0090368	regulation of ornithine metabolic process
0.50	GO:0006591	ornithine metabolic process
0.50	GO:0009065	glutamine family amino acid catabolic process
0.33	GO:0016311	dephosphorylation

0.82	GO:0004053	arginase activity
0.55	GO:0090369	ornithine carbamoyltransferase inhibitor activity
0.53	GO:0046872	metal ion binding
0.33	GO:0016791	phosphatase activity

0.46	GO:0005829	cytosol
0.36	GO:0005739	mitochondrion

0.82

EC:3.5.3.1

GO:0004053

tr|O76896|O76896_DROME
CG4293, isoform A
Search

0.10	endoplasmic reticulum-Golgi intermediate compartment protein 2

0.43	GO:0006888	ER to Golgi vesicle-mediated transport
0.34	GO:0043968	histone H2A acetylation
0.34	GO:0043967	histone H4 acetylation
0.33	GO:0006468	protein phosphorylation
0.33	GO:0006338	chromatin remodeling
0.33	GO:0045892	negative regulation of transcription, DNA-templated
0.33	GO:0046854	phosphatidylinositol phosphorylation
0.33	GO:0051716	cellular response to stimulus
0.32	GO:0032259	methylation
0.32	GO:0006950	response to stress

0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0016301	kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0099600	transmembrane receptor activity
0.32	GO:0008168	methyltransferase activity
0.32	GO:0038023	signaling receptor activity

0.43	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.33	GO:0035267	NuA4 histone acetyltransferase complex
0.30	GO:0016020	membrane

0.34

GO:0016773

tr|O76899|O76899_DROME
EG:80H7.2 protein
Search

0.64	Transmembrane protein 56-B

0.57	GO:0035002	liquid clearance, open tracheal system
0.57	GO:0060857	establishment of glial blood-brain barrier
0.56	GO:0019991	septate junction assembly
0.56	GO:0035151	regulation of tube size, open tracheal system
0.35	GO:0006508	proteolysis

0.37

GO:0004252

serine-type endopeptidase activity

0.56	GO:0005918	septate junction
0.30	GO:0044425	membrane part

0.37

GO:0004252

tr|O76901|O76901_DROME
EG:80H7.4 protein
Search

RAB27A

0.71	GTP-binding nuclear protein RAN1, putative

0.52	GO:0045921	positive regulation of exocytosis
0.49	GO:0071985	multivesicular body sorting pathway
0.47	GO:1990182	exosomal secretion
0.46	GO:0032402	melanosome transport
0.39	GO:0032482	Rab protein signal transduction
0.35	GO:0045055	regulated exocytosis
0.34	GO:0090522	vesicle tethering involved in exocytosis
0.34	GO:2000294	positive regulation of defecation
0.33	GO:1903364	positive regulation of cellular protein catabolic process

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0031489	myosin V binding
0.47	GO:0019904	protein domain specific binding

0.52	GO:0042470	melanosome
0.52	GO:0032585	multivesicular body membrane
0.49	GO:0030140	trans-Golgi network transport vesicle
0.48	GO:0005795	Golgi stack
0.45	GO:0099503	secretory vesicle
0.40	GO:0098793	presynapse
0.37	GO:0016324	apical plasma membrane
0.37	GO:0031225	anchored component of membrane
0.37	GO:0030658	transport vesicle membrane
0.36	GO:0031300	intrinsic component of organelle membrane

sp|O76902|PKHF1_DROME
Pleckstrin homology domain-containing family F member 1 homolog
Search

0.74	Pleckstrin domain-containing family F member

0.44	GO:0008333	endosome to lysosome transport
0.43	GO:0007032	endosome organization
0.40	GO:0006897	endocytosis
0.33	GO:0015031	protein transport
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.53	GO:0046872	metal ion binding
0.41	GO:0035091	phosphatidylinositol binding
0.35	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.33	GO:0003735	structural constituent of ribosome

0.44	GO:0031410	cytoplasmic vesicle
0.42	GO:0012505	endomembrane system
0.35	GO:0016324	apical plasma membrane
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0005938	cell cortex
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005840	ribosome
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.35	EC:3.2.1.113	GO:0004571
0.35	KEGG:R05982 KEGG:R06722	GO:0004571

tr|O76904|O76904_DROME
EG:8D8.1 protein
Search

0.87	GO:0007305	vitelline membrane formation involved in chorion-containing eggshell formation
0.86	GO:0007362	terminal region determination
0.30	GO:0007306	eggshell chorion assembly

0.37	GO:0008080	N-acetyltransferase activity
0.30	GO:0097367	carbohydrate derivative binding
0.30	GO:0043167	ion binding
0.30	GO:1901681	sulfur compound binding

0.87	GO:0060388	vitelline envelope
0.86	GO:0045172	germline ring canal
0.81	GO:0009897	external side of plasma membrane
0.48	GO:0005737	cytoplasm

0.37

GO:0008080

sp|O76906|CRM_DROME
Protein cramped
Search

0.49	GO:0007379	segment specification
0.39	GO:0006351	transcription, DNA-templated
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression
0.34	GO:0006414	translational elongation

0.46	GO:0003682	chromatin binding
0.44	GO:0003677	DNA binding
0.34	GO:0003746	translation elongation factor activity
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.57	GO:0005634	nucleus
0.34	GO:0005576	extracellular region
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|O76908|VILYA_DROME
RING finger protein vilya
Search

0.92	RING finger protein vilya

0.88	GO:1903343	positive regulation of meiotic DNA double-strand break formation
0.79	GO:0007143	female meiotic nuclear division

0.40

GO:0046872

metal ion binding

0.87	GO:0005713	recombination nodule
0.85	GO:0000795	synaptonemal complex
0.76	GO:0035861	site of double-strand break

tr|O76912|O76912_DROME
CG2701
Search

ASCC2

0.62	LOW QUALITY PROTEIN: activating signal cointegrator 1 complex subunit 2

0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.42	GO:2001141	regulation of RNA biosynthetic process
0.42	GO:0010468	regulation of gene expression
0.41	GO:0055114	oxidation-reduction process
0.37	GO:0003333	amino acid transmembrane transport

0.48	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.46	GO:0020037	heme binding
0.46	GO:0005506	iron ion binding
0.37	GO:0015171	amino acid transmembrane transporter activity
0.34	GO:0003676	nucleic acid binding

0.59	GO:0099053	activating signal cointegrator 1 complex
0.44	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.48

GO:0016705

sp|O76922|AUB_DROME
Protein aubergine
Search

0.85

Aubergine

0.79	GO:0031047	gene silencing by RNA
0.60	GO:0007279	pole cell formation
0.59	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.58	GO:0010529	negative regulation of transposition
0.56	GO:0009994	oocyte differentiation
0.55	GO:0016441	posttranscriptional gene silencing
0.54	GO:0006342	chromatin silencing
0.54	GO:0007317	regulation of pole plasm oskar mRNA localization
0.53	GO:0046843	dorsal appendage formation
0.53	GO:0007028	cytoplasm organization

0.54	GO:0034584	piRNA binding
0.36	GO:0003743	translation initiation factor activity
0.34	GO:0005515	protein binding
0.33	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.33	GO:0019843	rRNA binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0004519	endonuclease activity
0.33	GO:0046872	metal ion binding
0.31	GO:0030554	adenyl nucleotide binding
0.31	GO:0097367	carbohydrate derivative binding

0.52	GO:0043186	P granule
0.48	GO:0070725	Yb body
0.47	GO:0031933	telomeric heterochromatin
0.46	GO:0010369	chromocenter
0.46	GO:0000791	euchromatin
0.45	GO:0005700	polytene chromosome
0.41	GO:0005654	nucleoplasm
0.36	GO:0071011	precatalytic spliceosome
0.36	GO:0071013	catalytic step 2 spliceosome
0.33	GO:0005829	cytosol

0.33

EC:3.4.19.12

GO:0036459

sp|O76924|ARI2_DROME
Potential E3 ubiquitin-protein ligase ariadne-2
Search

0.58	Potential E3 ubiquitin-protein ligase ariadne-2

0.73	GO:0016567	protein ubiquitination
0.49	GO:0071425	hematopoietic stem cell proliferation
0.48	GO:1903955	positive regulation of protein targeting to mitochondrion
0.47	GO:0048588	developmental cell growth
0.47	GO:0006511	ubiquitin-dependent protein catabolic process
0.44	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.32	GO:0055114	oxidation-reduction process

0.73	GO:0004842	ubiquitin-protein transferase activity
0.54	GO:0046872	metal ion binding
0.51	GO:0031624	ubiquitin conjugating enzyme binding
0.47	GO:0016874	ligase activity
0.42	GO:0061659	ubiquitin-like protein ligase activity
0.34	GO:0031418	L-ascorbic acid binding
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0003676	nucleic acid binding

0.50	GO:0031466	Cul5-RING ubiquitin ligase complex
0.43	GO:0005654	nucleoplasm
0.37	GO:0005737	cytoplasm

0.47	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

sp|O76927|RS21_DROME
40S ribosomal protein S21
Search

RPS21

0.70	Ribosomal protein S21

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.46	GO:0048542	lymph gland development
0.44	GO:0016072	rRNA metabolic process
0.44	GO:0042254	ribosome biogenesis
0.43	GO:0006417	regulation of translation
0.43	GO:0042127	regulation of cell proliferation
0.39	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.64	GO:0003735	structural constituent of ribosome
0.46	GO:0047485	protein N-terminus binding
0.43	GO:0043022	ribosome binding
0.33	GO:0035091	phosphatidylinositol binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0003723	RNA binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.46	GO:0005844	polysome
0.44	GO:0044445	cytosolic part
0.40	GO:0044446	intracellular organelle part
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0005769	early endosome
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0098562	cytoplasmic side of membrane
0.33	GO:0098588	bounding membrane of organelle

tr|O76928|O76928_DROME
Carmine, isoform A
Search

AP3M1

0.82	Adaptor protein-3 subunit

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.50	GO:0008089	anterograde axonal transport
0.49	GO:0047496	vesicle transport along microtubule
0.48	GO:0097480	establishment of synaptic vesicle localization
0.47	GO:0033060	ocellus pigmentation
0.47	GO:0007220	Notch receptor processing
0.46	GO:0006726	eye pigment biosynthetic process
0.45	GO:0008340	determination of adult lifespan
0.42	GO:0044550	secondary metabolite biosynthetic process

0.46	GO:0017137	Rab GTPase binding
0.34	GO:0008565	protein transporter activity

0.79	GO:0030131	clathrin adaptor complex
0.49	GO:1904115	axon cytoplasm
0.38	GO:0030659	cytoplasmic vesicle membrane
0.37	GO:0005794	Golgi apparatus
0.35	GO:0030123	AP-3 adaptor complex
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0005764	lysosome
0.34	GO:0030136	clathrin-coated vesicle
0.34	GO:0044437	vacuolar part

sp|O76932|PP4C_DROME
Serine/threonine-protein phosphatase 4 catalytic subunit
Search

0.51	Serine/threonine-protein phosphatase 4 catalytic subunit

0.71	GO:0006470	protein dephosphorylation
0.48	GO:0010569	regulation of double-strand break repair via homologous recombination
0.45	GO:0045879	negative regulation of smoothened signaling pathway
0.42	GO:0007346	regulation of mitotic cell cycle
0.41	GO:0000278	mitotic cell cycle
0.41	GO:0007017	microtubule-based process
0.36	GO:0038061	NIK/NF-kappaB signaling
0.34	GO:0006801	superoxide metabolic process
0.33	GO:0006886	intracellular protein transport
0.33	GO:0016192	vesicle-mediated transport

0.72	GO:0004721	phosphoprotein phosphatase activity
0.37	GO:0004704	NF-kappaB-inducing kinase activity
0.35	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding
0.33	GO:0005198	structural molecule activity

0.51	GO:0030289	protein phosphatase 4 complex
0.44	GO:0005815	microtubule organizing center
0.43	GO:0005634	nucleus
0.42	GO:0000775	chromosome, centromeric region
0.42	GO:0005829	cytosol
0.38	GO:0005886	plasma membrane
0.33	GO:0030117	membrane coat
0.33	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.72

GO:0004721

tr|O76994|O76994_DROME
GM13959p
Search

0.72	TGF beta-inducible nuclear protein 1

0.56	GO:0006412	translation
0.47	GO:0000470	maturation of LSU-rRNA
0.46	GO:0000460	maturation of 5.8S rRNA

0.60

GO:0003735

structural constituent of ribosome

0.60	GO:1990904	ribonucleoprotein complex
0.58	GO:0043232	intracellular non-membrane-bounded organelle
0.53	GO:0044444	cytoplasmic part
0.42	GO:0031981	nuclear lumen

sp|O77051|E2F2_DROME
Transcription factor E2F2
Search

0.82	E2F transcription factor 2, isoform B

0.59	GO:0042023	DNA endoreduplication
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0051053	negative regulation of DNA metabolic process
0.54	GO:0043066	negative regulation of apoptotic process
0.50	GO:1902679	negative regulation of RNA biosynthetic process
0.40	GO:0007113	endomitotic cell cycle

0.64	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.53	GO:0001067	regulatory region nucleic acid binding
0.51	GO:0008134	transcription factor binding
0.34	GO:0003993	acid phosphatase activity
0.34	GO:0004527	exonuclease activity

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.60	GO:0031523	Myb complex
0.51	GO:0000785	chromatin
0.31	GO:0005737	cytoplasm

0.34

EC:3.1.3.2

GO:0003993

sp|O77059|CRY1_DROME
Cryptochrome-1
Search

CRY1

0.24	FAD binding domain of DNA photolyase

0.77	GO:0050958	magnetoreception
0.76	GO:0043153	entrainment of circadian clock by photoperiod
0.74	GO:0071000	response to magnetism
0.73	GO:0032922	circadian regulation of gene expression
0.72	GO:0000060	protein import into nucleus, translocation
0.72	GO:0042332	gravitaxis
0.70	GO:0050962	detection of light stimulus involved in sensory perception
0.70	GO:0045187	regulation of circadian sleep/wake cycle, sleep
0.70	GO:0045475	locomotor rhythm
0.69	GO:0009785	blue light signaling pathway

0.69	GO:0009882	blue light photoreceptor activity
0.63	GO:0071949	FAD binding
0.53	GO:0016829	lyase activity
0.50	GO:0035257	nuclear hormone receptor binding
0.47	GO:0019901	protein kinase binding
0.47	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.43	GO:0008020	G-protein coupled photoreceptor activity
0.39	GO:0140097	catalytic activity, acting on DNA
0.38	GO:0019902	phosphatase binding
0.37	GO:0000989	transcription factor activity, transcription factor binding

0.73	GO:0005641	nuclear envelope lumen
0.50	GO:0043234	protein complex
0.49	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0016607	nuclear speck
0.47	GO:0005829	cytosol
0.41	GO:0005739	mitochondrion
0.35	GO:0005576	extracellular region

0.53

EC:4

GO:0016829

tr|O77062|O77062_DROME
Amino acid transporter
Search

0.45	Amino acid transporter

0.55	GO:0089712	L-aspartate transmembrane transport
0.54	GO:0014853	regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
0.52	GO:0008345	larval locomotory behavior
0.52	GO:0089711	L-glutamate transmembrane transport
0.50	GO:0008340	determination of adult lifespan
0.47	GO:0007268	chemical synaptic transmission
0.43	GO:1903712	cysteine transmembrane transport
0.43	GO:0140016	D-aspartate import across plasma membrane
0.42	GO:1903802	L-glutamate(1-) import across plasma membrane
0.42	GO:0001504	neurotransmitter uptake

0.72	GO:0015293	symporter activity
0.52	GO:0015183	L-aspartate transmembrane transporter activity
0.52	GO:0005313	L-glutamate transmembrane transporter activity
0.48	GO:0015081	sodium ion transmembrane transporter activity
0.46	GO:0022853	active ion transmembrane transporter activity
0.43	GO:0033229	cysteine transmembrane transporter activity
0.39	GO:0015108	chloride transmembrane transporter activity
0.35	GO:0016595	glutamate binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding

0.50	GO:0043195	terminal bouton
0.50	GO:0031594	neuromuscular junction
0.40	GO:0016324	apical plasma membrane
0.37	GO:0005887	integral component of plasma membrane
0.33	GO:0070062	extracellular exosome

sp|O77086|C3G_DROME
Guanine nucleotide-releasing factor 2
Search

C3G

0.78	Guanine nucleotide-releasing factor 2

0.76	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.52	GO:0016203	muscle attachment
0.52	GO:0007525	somatic muscle development
0.51	GO:0045214	sarcomere organization

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.47	GO:0017016	Ras GTPase binding
0.38	GO:0017124	SH3 domain binding

0.45

GO:0005622

intracellular

tr|O77134|O77134_DROME
9 kD basic protein
Search

0.71	Mitochondrial ATP synthase subunit e

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.38	GO:0050909	sensory perception of taste
0.35	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.33	GO:0007165	signal transduction

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.36	GO:0016887	ATPase activity
0.35	GO:0022853	active ion transmembrane transporter activity
0.35	GO:0015399	primary active transmembrane transporter activity
0.34	GO:0005525	GTP binding
0.34	GO:0004871	signal transducer activity

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.36

GO:0016887

tr|O77135|O77135_DROME
FI03211p
Search

SPN-B

0.89

Spindle B

0.69	GO:0009951	polarity specification of dorsal/ventral axis
0.67	GO:0009949	polarity specification of anterior/posterior axis
0.67	GO:0007294	germarium-derived oocyte fate determination
0.66	GO:0030717	karyosome formation
0.65	GO:0006281	DNA repair
0.63	GO:0008298	intracellular mRNA localization
0.43	GO:0007127	meiosis I
0.43	GO:0035825	homologous recombination
0.42	GO:0090735	DNA repair complex assembly
0.41	GO:0006312	mitotic recombination

0.70	GO:0008094	DNA-dependent ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0000150	recombinase activity
0.38	GO:0004520	endodeoxyribonuclease activity
0.34	GO:0046982	protein heterodimerization activity

0.41	GO:0033061	DNA recombinase mediator complex
0.38	GO:0005657	replication fork
0.38	GO:0044428	nuclear part
0.33	GO:0035861	site of double-strand break
0.30	GO:0016020	membrane

sp|O77150|IM02_DROME
Immune-induced peptide 2
Search

0.97	Immune-induced peptide 2

0.70	GO:0009617	response to bacterium
0.66	GO:0006952	defense response
0.50	GO:0006955	immune response

0.61	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|O77215|UNC4_DROME
Homeobox protein unc-4
Search

UNC-4

0.73	Homeobox protein unc-4

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.39	GO:0007399	nervous system development
0.38	GO:0030154	cell differentiation
0.36	GO:0097659	nucleic acid-templated transcription
0.35	GO:0010467	gene expression
0.35	GO:0034645	cellular macromolecule biosynthetic process

0.61

GO:0043565

sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|O77237|PELI_DROME
Protein pellino
Search

0.93	Adaptor protein pellino

0.85	GO:0008063	Toll signaling pathway
0.49	GO:1902524	positive regulation of protein K48-linked ubiquitination
0.48	GO:0008348	negative regulation of antimicrobial humoral response
0.48	GO:0045751	negative regulation of Toll signaling pathway
0.46	GO:0042325	regulation of phosphorylation
0.41	GO:1902533	positive regulation of intracellular signal transduction
0.41	GO:0010562	positive regulation of phosphorus metabolic process
0.41	GO:0000209	protein polyubiquitination
0.40	GO:0006955	immune response
0.34	GO:0070498	interleukin-1-mediated signaling pathway

0.44	GO:0019207	kinase regulator activity
0.41	GO:0061630	ubiquitin protein ligase activity
0.38	GO:0016874	ligase activity
0.34	GO:0004252	serine-type endopeptidase activity
0.33	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0005515	protein binding

0.38	GO:0005886	plasma membrane
0.36	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.38

GO:0016874

tr|O77259|O77259_DROME
EG:115C2.5 protein
Search

0.65	vacuolar protein sorting-associated protein 37C

0.82	GO:0032509	endosome transport via multivesicular body sorting pathway
0.65	GO:0015031	protein transport
0.48	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

0.83

GO:0000813

ESCRT I complex

tr|O77260|O77260_DROME
EG:115C2.6 protein
Search

0.55	histone H4 transcription factor

0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:0010468	regulation of gene expression

0.51	GO:0003676	nucleic acid binding
0.40	GO:0003713	transcription coactivator activity
0.36	GO:0003700	DNA binding transcription factor activity
0.33	GO:0046872	metal ion binding

0.36

GO:0005634

nucleus

tr|O77262|O77262_DROME
CG4025
Search

0.70	DNA damage-regulated autophagy modulator protein 1

0.72	GO:0007601	visual perception
0.69	GO:0010506	regulation of autophagy
0.35	GO:0045494	photoreceptor cell maintenance
0.34	GO:0006508	proteolysis

0.35

GO:0008234

cysteine-type peptidase activity

0.41	GO:0005764	lysosome
0.35	GO:0001917	photoreceptor inner segment
0.34	GO:0016324	apical plasma membrane
0.33	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0008234

sp|O77263|TRMB_DROME
tRNA (guanine-N(7)-)-methyltransferase
Search

0.55	tRNA (guanine-N(7)-)-methyltransferase

0.79	GO:0106004	tRNA (guanine-N7)-methylation
0.34	GO:0016192	vesicle-mediated transport
0.34	GO:0007076	mitotic chromosome condensation
0.34	GO:0006836	neurotransmitter transport
0.32	GO:0005975	carbohydrate metabolic process
0.32	GO:0055085	transmembrane transport
0.32	GO:0055114	oxidation-reduction process

0.80	GO:0008176	tRNA (guanine-N7-)-methyltransferase activity
0.69	GO:0000049	tRNA binding
0.34	GO:0051537	2 iron, 2 sulfur cluster binding
0.34	GO:0005328	neurotransmitter:sodium symporter activity
0.33	GO:0008061	chitin binding
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding
0.32	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.44	GO:0043527	tRNA methyltransferase complex
0.42	GO:0005829	cytosol
0.41	GO:0031974	membrane-enclosed lumen
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.80

EC:2.1.1.33

GO:0008176

sp|O77264|RTCA_DROME
RNA 3'-terminal phosphate cyclase
Search

0.43	RNA terminal phosphate cyclase domain 1

0.63	GO:0006396	RNA processing
0.59	GO:0048681	negative regulation of axon regeneration
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.31	GO:0010468	regulation of gene expression

0.85	GO:0003963	RNA-3'-phosphate cyclase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0008144	drug binding
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0032561	guanyl ribonucleotide binding

0.46	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:6.5.1.4

GO:0003963

sp|O77277|TORS_DROME
Torsin-like protein
Search

0.95

Torsin a

0.59	GO:0051085	chaperone cofactor-dependent protein refolding
0.56	GO:1903741	negative regulation of phosphatidate phosphatase activity
0.56	GO:0043104	positive regulation of GTP cyclohydrolase I activity
0.55	GO:0007504	larval fat body development
0.54	GO:0008057	eye pigment granule organization
0.53	GO:0048085	adult chitin-containing cuticle pigmentation
0.53	GO:0042053	regulation of dopamine metabolic process
0.53	GO:0070050	neuron cellular homeostasis
0.52	GO:0070328	triglyceride homeostasis
0.52	GO:0010883	regulation of lipid storage

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.41	GO:0008092	cytoskeletal protein binding
0.41	GO:0051082	unfolded protein binding
0.40	GO:0016887	ATPase activity
0.36	GO:0016757	transferase activity, transferring glycosyl groups
0.35	GO:0051787	misfolded protein binding

0.66	GO:0005635	nuclear envelope
0.64	GO:0005783	endoplasmic reticulum
0.49	GO:0070013	intracellular organelle lumen
0.42	GO:0045202	synapse
0.40	GO:0032299	ribonuclease H2 complex
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0031982	vesicle
0.35	GO:0031312	extrinsic component of organelle membrane
0.34	GO:0097458	neuron part
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

0.40

GO:0016887

sp|O77286|U239_DROME
Protein anon-73B1
Search

0.30

GO:0044425

membrane part

sp|O77410|EIF3E_DROME
Eukaryotic translation initiation factor 3 subunit E
Search

0.70	Eukaryotic translation initiation factor 3 subunit E

0.73	GO:0001731	formation of translation preinitiation complex
0.71	GO:0006446	regulation of translational initiation
0.43	GO:1902416	positive regulation of mRNA binding
0.41	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.40	GO:0045727	positive regulation of translation

0.73	GO:0003743	translation initiation factor activity
0.42	GO:0047485	protein N-terminus binding
0.41	GO:0045296	cadherin binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.78	GO:0005852	eukaryotic translation initiation factor 3 complex
0.72	GO:0016282	eukaryotic 43S preinitiation complex
0.72	GO:0033290	eukaryotic 48S preinitiation complex
0.47	GO:0005634	nucleus
0.38	GO:0005829	cytosol
0.38	GO:0043233	organelle lumen
0.36	GO:0044446	intracellular organelle part
0.34	GO:0005783	endoplasmic reticulum

tr|O77424|O77424_DROME
EG:114D9.1 protein
Search

0.13	calcineurin B homologous protein 2

0.50

GO:0010923

negative regulation of phosphatase activity

0.70

GO:0005509

calcium ion binding

0.40

GO:0005886

plasma membrane

tr|O77425|O77425_DROME
Ribokinase
Search

0.50	Ribokinase

0.76	GO:0006014	D-ribose metabolic process
0.71	GO:0046835	carbohydrate phosphorylation
0.71	GO:0019323	pentose catabolic process

0.77	GO:0004747	ribokinase activity
0.51	GO:0030554	adenyl nucleotide binding
0.50	GO:0097367	carbohydrate derivative binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0046872	metal ion binding
0.38	GO:0047590	5-dehydro-2-deoxygluconokinase activity
0.38	GO:0008865	fructokinase activity

0.55	GO:0005634	nucleus
0.46	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.77

EC:2.7.1.15

GO:0004747

tr|O77430|O77430_DROME
GEO01111p1
Search

0.72	S-phase kinase associate protein A

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.47	GO:0016310	phosphorylation
0.44	GO:0045886	negative regulation of synaptic growth at neuromuscular junction
0.44	GO:0042023	DNA endoreduplication
0.44	GO:0016322	neuron remodeling
0.44	GO:0046329	negative regulation of JNK cascade
0.44	GO:0046627	negative regulation of insulin receptor signaling pathway
0.43	GO:0051298	centrosome duplication
0.43	GO:0010498	proteasomal protein catabolic process
0.42	GO:0045931	positive regulation of mitotic cell cycle

0.49	GO:0016301	kinase activity
0.39	GO:0097602	cullin family protein binding
0.39	GO:0008013	beta-catenin binding
0.38	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0019904	protein domain specific binding
0.37	GO:0061659	ubiquitin-like protein ligase activity
0.37	GO:0016874	ligase activity
0.34	GO:0004806	triglyceride lipase activity
0.33	GO:0004721	phosphoprotein phosphatase activity

0.49	GO:0019005	SCF ubiquitin ligase complex
0.47	GO:0031467	Cul7-RING ubiquitin ligase complex
0.40	GO:0005829	cytosol
0.40	GO:0005813	centrosome
0.38	GO:0031519	PcG protein complex
0.35	GO:0070062	extracellular exosome
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.37	EC:6	GO:0016874
0.38	KEGG:R03876	GO:0004842

tr|O77436|O77436_DROME
EG:34F3.5 protein
Search

0.38	Ribosomal RNA large subunit methyltransferase L

0.40	GO:0032259	methylation
0.39	GO:0016310	phosphorylation

0.51

GO:0016740

transferase activity

0.35	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.51

GO:0016740

sp|O77438|FRIZ3_DROME
Frizzled-3
Search

FZ3

0.84	Frizzled-3

0.74	GO:0016055	Wnt signaling pathway
0.68	GO:0007275	multicellular organism development
0.42	GO:0007163	establishment or maintenance of cell polarity
0.41	GO:0007186	G-protein coupled receptor signaling pathway

0.70	GO:0099600	transmembrane receptor activity
0.65	GO:0038023	signaling receptor activity
0.46	GO:0017147	Wnt-protein binding
0.37	GO:0003723	RNA binding

0.30

GO:0031224

intrinsic component of membrane

sp|O77459|KEN_DROME
Transcription factor Ken
Search

KEN

0.87	Transcription factor Ken

0.71	GO:0045497	female analia development
0.71	GO:0045496	male analia development
0.66	GO:0030540	female genitalia development
0.65	GO:0030539	male genitalia development
0.62	GO:0046425	regulation of JAK-STAT cascade
0.47	GO:1903506	regulation of nucleic acid-templated transcription
0.47	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.46	GO:0010468	regulation of gene expression
0.41	GO:0007620	copulation
0.41	GO:0007259	JAK-STAT cascade

0.51	GO:0003676	nucleic acid binding
0.49	GO:0003700	DNA binding transcription factor activity
0.39	GO:0046872	metal ion binding
0.32	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.32	GO:0000829	inositol heptakisphosphate kinase activity

0.49	GO:0005634	nucleus
0.37	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part
0.33	GO:0048471	perinuclear region of cytoplasm

sp|O77460|IPYR_DROME
Inorganic pyrophosphatase
Search

0.41	Inorganic pyrophosphatase

0.55	GO:0006796	phosphate-containing compound metabolic process
0.49	GO:0035206	regulation of hemocyte proliferation
0.48	GO:0035076	ecdysone receptor-mediated signaling pathway
0.48	GO:0042766	nucleosome mobilization
0.47	GO:0045747	positive regulation of Notch signaling pathway
0.39	GO:0006351	transcription, DNA-templated
0.34	GO:0016569	covalent chromatin modification
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:0010468	regulation of gene expression

0.78	GO:0004427	inorganic diphosphatase activity
0.64	GO:0000287	magnesium ion binding
0.36	GO:0070615	nucleosome-dependent ATPase activity
0.33	GO:0016853	isomerase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.49	GO:0005737	cytoplasm
0.47	GO:0016589	NURF complex
0.30	GO:0031224	intrinsic component of membrane

0.78	EC:3.6.1.1	GO:0004427
0.78	KEGG:R00004	GO:0004427

sp|O77475|CPESY_DROME
Ceramide phosphoethanolamine synthase
Search

0.28	Ceramide phosphoethanolamine synthase

0.41	GO:0044255	cellular lipid metabolic process
0.40	GO:0008610	lipid biosynthetic process
0.39	GO:0090407	organophosphate biosynthetic process
0.37	GO:0006796	phosphate-containing compound metabolic process
0.35	GO:0044249	cellular biosynthetic process
0.33	GO:1901564	organonitrogen compound metabolic process

0.51	GO:0004386	helicase activity
0.43	GO:0030554	adenyl nucleotide binding
0.43	GO:0097367	carbohydrate derivative binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0008144	drug binding
0.41	GO:0016780	phosphotransferase activity, for other substituted phosphate groups

0.37	GO:0000139	Golgi membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.41

EC:2.7.8

GO:0016780

tr|O77477|O77477_DROME
CG4882, isoform A
Search

0.46

GO:0006413

translational initiation

0.46

GO:0003743

translation initiation factor activity

0.52	GO:0044444	cytoplasmic part
0.50	GO:1990904	ribonucleoprotein complex
0.50	GO:0043229	intracellular organelle
0.49	GO:0043228	non-membrane-bounded organelle
0.45	GO:0043227	membrane-bounded organelle
0.30	GO:0044425	membrane part

tr|O96067|O96067_DROME
DJTB-like protein
Search

0.81	Jumping translocation breakpoint protein

0.34

GO:0006955

immune response

0.35

GO:0005164

tumor necrosis factor receptor binding

0.30

GO:0044425

membrane part

tr|O96299|O96299_DROME
LD47736p
Search

0.37	sorbitol dehydrogenase

0.53

GO:0055114

oxidation-reduction process

0.61	GO:0008270	zinc ion binding
0.52	GO:0016491	oxidoreductase activity

0.30

GO:0044425

membrane part

0.52

GO:0016491

tr|O96395|O96395_DROME
LD05664p
Search

0.58	Meiotic central spindle, isoform B

0.47	GO:1903506	regulation of nucleic acid-templated transcription
0.47	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.47	GO:0010468	regulation of gene expression
0.41	GO:0040034	regulation of development, heterochronic
0.37	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage
0.37	GO:1902679	negative regulation of RNA biosynthetic process
0.36	GO:0044092	negative regulation of molecular function
0.35	GO:0045668	negative regulation of osteoblast differentiation
0.35	GO:0060041	retina development in camera-type eye
0.34	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.46	GO:0046872	metal ion binding
0.41	GO:0003700	DNA binding transcription factor activity
0.39	GO:0042826	histone deacetylase binding
0.37	GO:0003682	chromatin binding
0.33	GO:0005044	scavenger receptor activity
0.33	GO:0005543	phospholipid binding

0.53	GO:0005876	spindle microtubule
0.50	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.35	GO:0043233	organelle lumen
0.33	GO:0015629	actin cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

sp|O96433|CCNT_DROME
Cyclin-T
Search

CYCT

0.78

Cyclin-T

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.51	GO:0009408	response to heat
0.46	GO:0006351	transcription, DNA-templated
0.43	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.41	GO:1902680	positive regulation of RNA biosynthetic process
0.40	GO:0007419	ventral cord development
0.40	GO:0019085	early viral transcription
0.40	GO:0019086	late viral transcription

0.75	GO:0019901	protein kinase binding
0.43	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.42	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.39	GO:0097322	7SK snRNA binding
0.39	GO:0001223	transcription coactivator binding
0.37	GO:0070063	RNA polymerase binding
0.37	GO:0003682	chromatin binding
0.32	GO:0016491	oxidoreductase activity

0.59	GO:0008024	cyclin/CDK positive transcription elongation factor complex
0.57	GO:0005703	polytene chromosome puff
0.57	GO:0032783	ELL-EAF complex
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005829	cytosol
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.43

GO:0016538

tr|O96532|O96532_DROME
Rad17
Search

RAD17

0.55	cell cycle checkpoint protein RAD17

0.67	GO:0007049	cell cycle
0.65	GO:0006281	DNA repair
0.43	GO:0000076	DNA replication checkpoint
0.42	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle
0.42	GO:0000077	DNA damage checkpoint

0.42	GO:0003689	DNA clamp loader activity
0.41	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.40	GO:0000785	chromatin
0.39	GO:0031974	membrane-enclosed lumen

sp|O96539|ATE1_DROME
Arginyl-tRNA--protein transferase 1
Search

0.76	Arginyl-tRNA--protein transferase 1

0.82	GO:0016598	protein arginylation
0.38	GO:0010498	proteasomal protein catabolic process

0.82

GO:0004057

arginyltransferase activity

0.35	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.82

EC:2.3.2.8

GO:0004057

sp|O96553|C1TC_DROME
C-1-tetrahydrofolate synthase, cytoplasmic
Search

0.68	Methylenetetrahydrofolate dehydrogenase

0.52	GO:0055114	oxidation-reduction process
0.42	GO:0009257	10-formyltetrahydrofolate biosynthetic process
0.39	GO:0009113	purine nucleobase biosynthetic process
0.36	GO:0035999	tetrahydrofolate interconversion
0.35	GO:0009086	methionine biosynthetic process
0.35	GO:0000105	histidine biosynthetic process
0.35	GO:0006164	purine nucleotide biosynthetic process

0.80	GO:0004329	formate-tetrahydrofolate ligase activity
0.77	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity

0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.80	EC:6.3.4.3	GO:0004329
0.77	KEGG:R01220	GO:0004488

sp|O96651|TOP3B_DROME
DNA topoisomerase 3-beta
Search

0.55	DNA topoisomerase

0.72	GO:0006265	DNA topological change
0.48	GO:0051965	positive regulation of synapse assembly
0.44	GO:0007059	chromosome segregation

0.77	GO:0003917	DNA topoisomerase type I activity
0.55	GO:0003677	DNA binding
0.33	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.45	GO:0000793	condensed chromosome
0.38	GO:0005634	nucleus

0.77

EC:5.99.1.2

GO:0003917

tr|O96660|O96660_DROME
Mothers against decapentaplegic homolog
Search

0.54	Mothers against decapentaplegic homolog

0.79	GO:0007179	transforming growth factor beta receptor signaling pathway
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0006351	transcription, DNA-templated
0.54	GO:0090256	regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis
0.51	GO:0016319	mushroom body development
0.49	GO:0008340	determination of adult lifespan
0.48	GO:0007411	axon guidance
0.46	GO:0007346	regulation of mitotic cell cycle

0.59	GO:0003700	DNA binding transcription factor activity
0.53	GO:0003677	DNA binding
0.47	GO:0003682	chromatin binding
0.36	GO:0005515	protein binding

0.71	GO:0005667	transcription factor complex
0.59	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|O96689|O96689_DROME
FI11703p
Search

0.61	Double-strand-break repair protein rad21

0.58	GO:0016322	neuron remodeling
0.57	GO:0070193	synaptonemal complex organization
0.55	GO:0007064	mitotic sister chromatid cohesion
0.50	GO:0010628	positive regulation of gene expression
0.40	GO:0006302	double-strand break repair
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process

0.45	GO:0003682	chromatin binding
0.37	GO:0003924	GTPase activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003735	structural constituent of ribosome

0.71	GO:0000228	nuclear chromosome
0.58	GO:0005705	polytene chromosome interband
0.58	GO:0008278	cohesin complex
0.56	GO:0005721	pericentric heterochromatin
0.34	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

sp|O96690|PDF_DROME
Protein PDF
Search

PDF

0.84	Pigment-dispersing hormone

0.76	GO:0009416	response to light stimulus
0.76	GO:0010469	regulation of receptor activity
0.66	GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness
0.65	GO:1904059	regulation of locomotor rhythm
0.64	GO:0042332	gravitaxis
0.64	GO:0042745	circadian sleep/wake cycle
0.62	GO:0009649	entrainment of circadian clock
0.62	GO:0045475	locomotor rhythm
0.61	GO:0007617	mating behavior
0.60	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.39	GO:0005622	intracellular
0.30	GO:0016020	membrane

tr|O96692|O96692_DROME
RE63021p
Search

0.73	Putative rab subfamily protein of small gtpase

0.61	GO:0007165	signal transduction
0.50	GO:0031954	positive regulation of protein autophosphorylation
0.47	GO:0030336	negative regulation of cell migration
0.47	GO:0032501	multicellular organismal process
0.45	GO:0034109	homotypic cell-cell adhesion
0.44	GO:0030033	microvillus assembly
0.44	GO:0098727	maintenance of cell number
0.43	GO:0007599	hemostasis
0.43	GO:0061097	regulation of protein tyrosine kinase activity
0.43	GO:0050773	regulation of dendrite development

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0019904	protein domain specific binding
0.38	GO:0000287	magnesium ion binding

0.49	GO:0055038	recycling endosome membrane
0.44	GO:0044291	cell-cell contact zone
0.44	GO:0070062	extracellular exosome
0.43	GO:0005829	cytosol
0.43	GO:0005923	bicellular tight junction
0.43	GO:0045121	membrane raft
0.39	GO:0005886	plasma membrane
0.36	GO:0030496	midbody
0.30	GO:0016021	integral component of membrane

tr|O96824|O96824_DROME
EG:131F2.3 protein
Search

0.85	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.74	GO:0071230	cellular response to amino acid stimulus
0.73	GO:1904263	positive regulation of TORC1 signaling
0.70	GO:0019079	viral genome replication

0.85

GO:0071986

Ragulator complex

sp|O96827|EF1B_DROME
Probable elongation factor 1-beta
Search

0.61	Eukaryotic translation elongation factor 1 beta

0.70

GO:0006414

translational elongation

0.71

GO:0003746

translation elongation factor activity

0.84	GO:0005853	eukaryotic translation elongation factor 1 complex
0.30	GO:0031224	intrinsic component of membrane

sp|O96838|FYV1_DROME
Putative 1-phosphatidylinositol 3-phosphate 5-kinase
Search

0.57	1-phosphatidylinositol-3-phosphate 5-kinase

0.74	GO:0046854	phosphatidylinositol phosphorylation
0.63	GO:0097352	autophagosome maturation
0.63	GO:0008333	endosome to lysosome transport
0.58	GO:0035556	intracellular signal transduction
0.43	GO:0006458	'de novo' protein folding
0.42	GO:0061077	chaperone-mediated protein folding
0.37	GO:0042147	retrograde transport, endosome to Golgi
0.34	GO:2000785	regulation of autophagosome assembly
0.33	GO:0032288	myelin assembly
0.32	GO:0034504	protein localization to nucleus

0.81	GO:0016307	phosphatidylinositol phosphate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.44	GO:0044183	protein binding involved in protein folding
0.41	GO:0051082	unfolded protein binding
0.32	GO:0032266	phosphatidylinositol-3-phosphate binding

0.57	GO:0005768	endosome
0.42	GO:0005832	chaperonin-containing T-complex
0.41	GO:0044433	cytoplasmic vesicle part
0.41	GO:0098805	whole membrane
0.40	GO:0098588	bounding membrane of organelle
0.40	GO:0012506	vesicle membrane
0.32	GO:0048471	perinuclear region of cytoplasm
0.32	GO:0005911	cell-cell junction
0.32	GO:0035032	phosphatidylinositol 3-kinase complex, class III
0.32	GO:0000324	fungal-type vacuole

0.81

GO:0016307

sp|O96860|DYL2_DROME
Dynein light chain 2, cytoplasmic
Search

0.65	Dynein light chain cytoplasmic

0.72	GO:0007017	microtubule-based process
0.48	GO:2000582	positive regulation of ATP-dependent microtubule motor activity, plus-end-directed
0.46	GO:0030705	cytoskeleton-dependent intracellular transport
0.45	GO:0060271	cilium assembly
0.42	GO:0006928	movement of cell or subcellular component
0.41	GO:1902857	positive regulation of non-motile cilium assembly
0.39	GO:0042326	negative regulation of phosphorylation
0.39	GO:0031503	protein complex localization
0.39	GO:0007286	spermatid development
0.38	GO:0012501	programmed cell death

0.48	GO:0045505	dynein intermediate chain binding
0.47	GO:0051959	dynein light intermediate chain binding
0.47	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed
0.43	GO:0008092	cytoskeletal protein binding
0.40	GO:0019904	protein domain specific binding
0.39	GO:0008022	protein C-terminus binding
0.38	GO:0030235	nitric-oxide synthase regulator activity
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0097110	scaffold protein binding
0.36	GO:0046982	protein heterodimerization activity

0.79	GO:0030286	dynein complex
0.42	GO:0005815	microtubule organizing center
0.41	GO:0072686	mitotic spindle
0.40	GO:0000776	kinetochore
0.40	GO:0008180	COP9 signalosome
0.40	GO:0005929	cilium
0.37	GO:1904115	axon cytoplasm
0.37	GO:0005874	microtubule
0.37	GO:0005829	cytosol
0.37	GO:0030141	secretory granule

0.47

EC:3.6.4.4

GO:0008574

sp|O96863|CSK2C_DROME
Casein kinase II subunit beta'
Search

0.56	Casein kinase II subunit beta'

0.76	GO:0045859	regulation of protein kinase activity
0.47	GO:0016310	phosphorylation
0.40	GO:0007310	oocyte dorsal/ventral axis specification
0.39	GO:0060810	intracellular mRNA localization involved in pattern specification process
0.39	GO:0016319	mushroom body development
0.39	GO:0045475	locomotor rhythm
0.38	GO:0001934	positive regulation of protein phosphorylation
0.38	GO:0033211	adiponectin-activated signaling pathway
0.38	GO:0032927	positive regulation of activin receptor signaling pathway
0.38	GO:0061154	endothelial tube morphogenesis

0.79	GO:0019887	protein kinase regulator activity
0.48	GO:0016301	kinase activity
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.36	GO:0019209	kinase activator activity
0.36	GO:0003682	chromatin binding
0.36	GO:0019904	protein domain specific binding
0.36	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0042802	identical protein binding
0.35	GO:0008134	transcription factor binding
0.35	GO:0005102	receptor binding

0.83	GO:0005956	protein kinase CK2 complex
0.37	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.35	GO:0005929	cilium
0.34	GO:0043204	perikaryon
0.34	GO:0044446	intracellular organelle part
0.34	GO:0005886	plasma membrane
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon
0.33	GO:0005694	chromosome

0.37

GO:0016773

tr|O96880|O96880_DROME
GH11150p
Search

0.77	Transcription initiation factor IIE subunit alpha

0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.44	GO:0051254	positive regulation of RNA metabolic process
0.44	GO:0010557	positive regulation of macromolecule biosynthetic process
0.44	GO:0031328	positive regulation of cellular biosynthetic process
0.41	GO:0006413	translational initiation
0.36	GO:0018108	peptidyl-tyrosine phosphorylation
0.34	GO:0042795	snRNA transcription by RNA polymerase II

0.64	GO:0043565	sequence-specific DNA binding
0.41	GO:0003743	translation initiation factor activity
0.36	GO:0004713	protein tyrosine kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046872	metal ion binding
0.32	GO:0005515	protein binding

0.50	GO:0090575	RNA polymerase II transcription factor complex
0.50	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
0.47	GO:0097550	transcriptional preinitiation complex
0.41	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0004713

tr|O96881|O96881_DROME
Transcription initiation factor IIE subunit beta
Search

0.75	Transcription initiation factor IIE subunit beta

0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0006413	translational initiation
0.44	GO:0051254	positive regulation of RNA metabolic process
0.43	GO:0010557	positive regulation of macromolecule biosynthetic process
0.43	GO:0031328	positive regulation of cellular biosynthetic process
0.35	GO:0032392	DNA geometric change
0.34	GO:0005975	carbohydrate metabolic process

0.55	GO:0003677	DNA binding
0.50	GO:0003743	translation initiation factor activity
0.37	GO:0004563	beta-N-acetylhexosaminidase activity
0.36	GO:0043140	ATP-dependent 3'-5' DNA helicase activity
0.35	GO:0008408	3'-5' exonuclease activity
0.34	GO:0016307	phosphatidylinositol phosphate kinase activity
0.34	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.84	GO:0005673	transcription factor TFIIE complex
0.36	GO:0016607	nuclear speck
0.36	GO:0005669	transcription factor TFIID complex
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.37

EC:3.2.1.52

GO:0004563

tr|O96989|O96989_DROME
CDC45L
Search

CDC45

0.56	Cell division control protein 45

0.75	GO:0006270	DNA replication initiation
0.54	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.54	GO:0006277	DNA amplification
0.52	GO:0051301	cell division
0.48	GO:0030261	chromosome condensation
0.47	GO:0032392	DNA geometric change
0.43	GO:1902977	mitotic DNA replication preinitiation complex assembly
0.42	GO:1902299	pre-replicative complex assembly involved in cell cycle DNA replication
0.42	GO:0031938	regulation of chromatin silencing at telomere
0.42	GO:0000727	double-strand break repair via break-induced replication

0.51	GO:0043138	3'-5' DNA helicase activity
0.50	GO:0003682	chromatin binding
0.40	GO:0003688	DNA replication origin binding
0.39	GO:0003697	single-stranded DNA binding
0.34	GO:0008408	3'-5' exonuclease activity
0.34	GO:0005515	protein binding
0.33	GO:0008270	zinc ion binding

0.54	GO:0005656	nuclear pre-replicative complex
0.41	GO:0031298	replication fork protection complex
0.41	GO:0031261	DNA replication preinitiation complex
0.37	GO:0005737	cytoplasm
0.37	GO:0005813	centrosome
0.30	GO:0016020	membrane

tr|O97042|O97042_DROME
KAZ1-type serine protease inhibitor-like protein type epsilon
Search

KAZ1-ORFB

0.92	KAZ1-type serine protease inhibitor-like protein type epsilon

0.48	GO:0006508	proteolysis
0.37	GO:0006904	vesicle docking involved in exocytosis

0.49

GO:0008233

peptidase activity

0.66	GO:0005576	extracellular region
0.60	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.49

GO:0008233

tr|O97059|O97059_DROME
Ccp84Ab
Search

0.50	larval cuticle protein A2B

0.45	GO:0040003	chitin-based cuticle development
0.35	GO:0032504	multicellular organism reproduction
0.32	GO:0007218	neuropeptide signaling pathway

0.77

GO:0042302

structural constituent of cuticle

0.41	GO:0031012	extracellular matrix
0.35	GO:0005615	extracellular space
0.33	GO:0070701	mucus layer
0.30	GO:0016020	membrane

tr|O97060|O97060_DROME
Ccp84Ac
Search

0.68	Pupal cuticle protein Edg-84A

0.38	GO:0040003	chitin-based cuticle development
0.33	GO:0000724	double-strand break repair via homologous recombination
0.33	GO:0048598	embryonic morphogenesis
0.32	GO:0006260	DNA replication

0.79	GO:0042302	structural constituent of cuticle
0.31	GO:0003677	DNA binding
0.31	GO:0046872	metal ion binding

0.36	GO:0031012	extracellular matrix
0.34	GO:0072669	tRNA-splicing ligase complex
0.34	GO:0030915	Smc5-Smc6 complex
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|O97061|O97061_DROME
Ccp84Ad
Search

0.53	larval cuticle protein A2B

0.43	GO:0040003	chitin-based cuticle development
0.36	GO:0032504	multicellular organism reproduction
0.32	GO:0007218	neuropeptide signaling pathway

0.77

GO:0042302

structural constituent of cuticle

0.40	GO:0031012	extracellular matrix
0.35	GO:0005615	extracellular space
0.34	GO:0070701	mucus layer
0.30	GO:0016020	membrane

tr|O97062|O97062_DROME
Ccp84Ae
Search

0.52	Pupal cuticle protein Edg-84A

0.44	GO:0040003	chitin-based cuticle development
0.37	GO:0048598	embryonic morphogenesis
0.34	GO:0032504	multicellular organism reproduction

0.79

GO:0042302

structural constituent of cuticle

0.41	GO:0031012	extracellular matrix
0.38	GO:0072669	tRNA-splicing ligase complex
0.34	GO:0005615	extracellular space
0.30	GO:0016020	membrane

tr|O97063|O97063_DROME
Ccp84Af
Search

CUA2B

0.57	Cuticular protein 5C

0.43	GO:0040003	chitin-based cuticle development
0.35	GO:0032504	multicellular organism reproduction

0.78

GO:0042302

structural constituent of cuticle

0.40	GO:0031012	extracellular matrix
0.34	GO:0005615	extracellular space
0.30	GO:0016020	membrane

tr|O97064|O97064_DROME
Ccp84Ag
Search

0.54	Cuticular protein RR-2 motif 69

0.44	GO:0040003	chitin-based cuticle development
0.35	GO:0048598	embryonic morphogenesis
0.34	GO:0032504	multicellular organism reproduction

0.79

GO:0042302

structural constituent of cuticle

0.41	GO:0031012	extracellular matrix
0.36	GO:0072669	tRNA-splicing ligase complex
0.34	GO:0005615	extracellular space
0.30	GO:0016020	membrane

tr|O97066|O97066_DROME
Signal peptidase complex catalytic subunit SEC11
Search

0.72	Signal peptidase complex catalytic subunit SEC11

0.80	GO:0006465	signal peptide processing
0.34	GO:0045116	protein neddylation

0.67	GO:0017171	serine hydrolase activity
0.62	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.34	GO:0019781	NEDD8 activating enzyme activity
0.33	GO:0016881	acid-amino acid ligase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.82	GO:0005787	signal peptidase complex
0.30	GO:0016021	integral component of membrane

0.33

EC:6.3.2

GO:0016881

sp|O97067|PTH2_DROME
Probable peptidyl-tRNA hydrolase 2
Search

0.38	Peptidyl-trna hydrolase

0.35	GO:0007030	Golgi organization
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.79

GO:0004045

aminoacyl-tRNA hydrolase activity

0.34	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:3.1.1.29

GO:0004045

sp|O97069|ASSY_DROME
Argininosuccinate synthase
Search

0.43	Argininosuccinate synthase

0.72	GO:0006526	arginine biosynthetic process
0.44	GO:0000053	argininosuccinate metabolic process
0.43	GO:0000050	urea cycle
0.37	GO:0071499	cellular response to laminar fluid shear stress
0.36	GO:0000052	citrulline metabolic process
0.36	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.36	GO:1903038	negative regulation of leukocyte cell-cell adhesion
0.36	GO:0006531	aspartate metabolic process
0.36	GO:0007623	circadian rhythm

0.80	GO:0004055	argininosuccinate synthase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0016597	amino acid binding
0.35	GO:0042802	identical protein binding

0.41	GO:0005737	cytoplasm
0.36	GO:0043209	myelin sheath
0.34	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0044446	intracellular organelle part

0.80

EC:6.3.4.5

GO:0004055

tr|O97102|O97102_DROME
Small ubiquitin-related modifier
Search

0.76	Small ubiquitin-related modifier

0.81	GO:0016925	protein sumoylation
0.45	GO:0034126	positive regulation of MyD88-dependent toll-like receptor signaling pathway
0.44	GO:0035186	syncytial blastoderm mitotic cell cycle
0.44	GO:0035073	pupariation
0.44	GO:0060997	dendritic spine morphogenesis
0.44	GO:0046843	dorsal appendage formation
0.43	GO:0016926	protein desumoylation
0.43	GO:0021952	central nervous system projection neuron axonogenesis
0.43	GO:1903078	positive regulation of protein localization to plasma membrane
0.43	GO:0046579	positive regulation of Ras protein signal transduction

0.43	GO:0031386	protein tag
0.36	GO:0005509	calcium ion binding
0.36	GO:0019899	enzyme binding
0.35	GO:0019887	protein kinase regulator activity
0.35	GO:0043022	ribosome binding
0.34	GO:0001222	transcription corepressor binding
0.34	GO:0019789	SUMO transferase activity
0.33	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.33	GO:0017171	serine hydrolase activity
0.33	GO:0030554	adenyl nucleotide binding

0.59	GO:0005634	nucleus
0.42	GO:0030496	midbody
0.42	GO:0000940	condensed chromosome outer kinetochore
0.40	GO:0070013	intracellular organelle lumen
0.33	GO:0005737	cytoplasm
0.33	GO:0045277	respiratory chain complex IV
0.32	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.32

GO:0016676

tr|O97111|O97111_DROME
LD29223p
Search

0.57	Partitioning defective 6 like protein gamma

0.78	GO:0007163	establishment or maintenance of cell polarity
0.52	GO:0007430	terminal branching, open tracheal system
0.51	GO:0010592	positive regulation of lamellipodium assembly
0.51	GO:0055059	asymmetric neuroblast division
0.51	GO:0051491	positive regulation of filopodium assembly
0.50	GO:0007298	border follicle cell migration
0.50	GO:0007416	synapse assembly
0.48	GO:0006469	negative regulation of protein kinase activity
0.39	GO:0007043	cell-cell junction assembly
0.37	GO:0045176	apical protein localization

0.34	GO:0005515	protein binding
0.34	GO:0016780	phosphotransferase activity, for other substituted phosphate groups
0.33	GO:0005509	calcium ion binding
0.33	GO:0004252	serine-type endopeptidase activity

0.52	GO:0097482	muscle cell postsynaptic specialization
0.51	GO:0045179	apical cortex
0.50	GO:0043195	terminal bouton
0.48	GO:0016324	apical plasma membrane
0.37	GO:0035003	subapical complex
0.34	GO:0005923	bicellular tight junction
0.34	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.7.8

GO:0016780

sp|O97125|HSP68_DROME
Heat shock protein 68
Search

0.63	Major heat shock 70 kDa protein Bbb

0.44	GO:0008340	determination of adult lifespan
0.42	GO:0042594	response to starvation
0.42	GO:0035080	heat shock-mediated polytene chromosome puffing
0.40	GO:0001666	response to hypoxia
0.38	GO:0006986	response to unfolded protein
0.34	GO:0010918	positive regulation of mitochondrial membrane potential
0.34	GO:0070584	mitochondrion morphogenesis
0.34	GO:0000422	autophagy of mitochondrion
0.33	GO:0006457	protein folding
0.33	GO:0009636	response to toxic substance

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0051082	unfolded protein binding
0.33	GO:0043565	sequence-specific DNA binding

0.33

GO:0005739

mitochondrion

tr|O97132|O97132_DROME
Anoctamin
Search

0.64

Anoctamin

0.64	GO:0032837	distributive segregation
0.63	GO:0016321	female meiosis chromosome segregation
0.61	GO:0000212	meiotic spindle organization
0.40	GO:1902476	chloride transmembrane transport
0.36	GO:0098655	cation transmembrane transport
0.34	GO:0061588	calcium activated phospholipid scrambling

0.42	GO:0061778	intracellular chloride channel activity
0.41	GO:0005227	calcium activated cation channel activity
0.33	GO:0046983	protein dimerization activity

0.61	GO:0005640	nuclear outer membrane
0.55	GO:0005819	spindle
0.55	GO:0005938	cell cortex
0.52	GO:0005783	endoplasmic reticulum
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|O97143|PLK4_DROME
Serine/threonine-protein kinase PLK4
Search

SAK

0.34	Serine/threonine protein kinase

0.85	GO:0007099	centriole replication
0.63	GO:0006468	protein phosphorylation
0.56	GO:0035186	syncytial blastoderm mitotic cell cycle
0.55	GO:0046599	regulation of centriole replication
0.55	GO:0007288	sperm axoneme assembly
0.53	GO:0007140	male meiotic nuclear division
0.51	GO:0045732	positive regulation of protein catabolic process
0.50	GO:0031647	regulation of protein stability
0.39	GO:0010825	positive regulation of centrosome duplication
0.39	GO:0098535	de novo centriole assembly involved in multi-ciliated epithelial cell differentiation

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0042802	identical protein binding
0.33	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.33	GO:0005509	calcium ion binding

0.83	GO:0005814	centriole
0.39	GO:0098536	deuterosome
0.37	GO:0001741	XY body
0.36	GO:0005730	nucleolus
0.36	GO:0005813	centrosome
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.70

GO:0004674

sp|O97148|MTH_DROME
G-protein coupled receptor Mth
Search

0.76	G-protein coupled receptor Mth

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.62	GO:0006950	response to stress
0.46	GO:0008340	determination of adult lifespan
0.44	GO:0031667	response to nutrient levels
0.37	GO:0016079	synaptic vesicle exocytosis
0.36	GO:0009266	response to temperature stimulus
0.36	GO:1901700	response to oxygen-containing compound
0.36	GO:0010033	response to organic substance
0.35	GO:0009636	response to toxic substance

0.72	GO:0004930	G-protein coupled receptor activity
0.36	GO:0042277	peptide binding
0.36	GO:0001653	peptide receptor activity
0.34	GO:0005549	odorant binding
0.34	GO:0005515	protein binding
0.34	GO:0004984	olfactory receptor activity
0.32	GO:0043565	sequence-specific DNA binding

0.38	GO:0005886	plasma membrane
0.36	GO:0098793	presynapse
0.31	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|O97159|CHDM_DROME
Chromodomain-helicase-DNA-binding protein Mi-2 homolog
Search

0.72	Chromodomain-helicase-DNA-binding protein Mi-2

0.64	GO:0007098	centrosome cycle
0.62	GO:0007051	spindle organization
0.57	GO:0006325	chromatin organization
0.38	GO:0071923	negative regulation of cohesin loading
0.38	GO:0051312	chromosome decondensation
0.36	GO:0007283	spermatogenesis
0.36	GO:0000122	negative regulation of transcription by RNA polymerase II
0.36	GO:0030261	chromosome condensation
0.36	GO:0071824	protein-DNA complex subunit organization
0.35	GO:0006351	transcription, DNA-templated

0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.52	GO:0004386	helicase activity
0.45	GO:0003677	DNA binding
0.41	GO:0016887	ATPase activity
0.37	GO:0031491	nucleosome binding
0.35	GO:0003899	DNA-directed 5'-3' RNA polymerase activity

0.67	GO:0090545	CHD-type complex
0.65	GO:0090568	nuclear transcriptional repressor complex
0.64	GO:0000118	histone deacetylase complex
0.37	GO:0035327	transcriptionally active chromatin
0.37	GO:0005700	polytene chromosome
0.36	GO:0005829	cytosol
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.41	EC:3.6.1.3	GO:0016887
0.34	KEGG:R03876	GO:0004842

sp|O97172|U729_DROME
UPF0729 protein CG18508
Search

0.35	Putative secreted protein (Fragment)

0.57

GO:0007165

signal transduction

0.59

GO:0004871

signal transducer activity

0.30

GO:0031224

intrinsic component of membrane

sp|O97176|ESM1_DROME
Enhancer of split M1 protein
Search

0.80	Enhancer of split region protein HLHm1

0.63	GO:0010951	negative regulation of endopeptidase activity
0.49	GO:0006508	proteolysis

0.65	GO:0004867	serine-type endopeptidase inhibitor activity
0.49	GO:0008233	peptidase activity
0.46	GO:0005509	calcium ion binding

0.30

GO:0044425

membrane part

0.49

GO:0008233

sp|O97177|ESM2_DROME
Enhancer of split M2 protein
Search

0.97	Enhancer of split m2 protein (Fragment)

0.82	GO:0007219	Notch signaling pathway
0.81	GO:0001708	cell fate specification
0.79	GO:0007423	sensory organ development
0.43	GO:0007399	nervous system development

0.30

GO:0003824

catalytic activity

sp|O97178|ESMA_DROME
Enhancer of split malpha protein
Search

MALPHA

0.97	Enhancer of split region protein HLHma

0.82	GO:0007219	Notch signaling pathway
0.79	GO:0007423	sensory organ development
0.65	GO:0001708	cell fate specification

0.62

GO:0031625

ubiquitin protein ligase binding

sp|O97179|ESM6_DROME
Enhancer of split m6 protein
Search

0.84	GO:0001708	cell fate specification
0.79	GO:0007423	sensory organ development
0.51	GO:0007219	Notch signaling pathway
0.48	GO:0007399	nervous system development

0.50

GO:0031625

ubiquitin protein ligase binding

tr|O97182|O97182_DROME
Actin related complex p41 subunit
Search

0.75	Actin-related protein 2/3 complex subunit

0.79	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.49	GO:0030589	pseudocleavage involved in syncytial blastoderm formation
0.48	GO:0030037	actin filament reorganization involved in cell cycle
0.48	GO:0008407	chaeta morphogenesis
0.47	GO:0033627	cell adhesion mediated by integrin
0.47	GO:0007413	axonal fasciculation
0.47	GO:0051491	positive regulation of filopodium assembly
0.46	GO:0045747	positive regulation of Notch signaling pathway
0.46	GO:0001745	compound eye morphogenesis
0.45	GO:0007409	axonogenesis

0.71	GO:0003779	actin binding
0.43	GO:0032403	protein complex binding
0.35	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0003774	motor activity

0.79	GO:0005885	Arp2/3 protein complex
0.52	GO:0036195	muscle cell projection membrane
0.48	GO:0005737	cytoplasm
0.35	GO:0070062	extracellular exosome
0.33	GO:0016459	myosin complex

tr|O97183|O97183_DROME
GH07456p
Search

0.50	DNA-directed RNA polymerase II polypeptide

0.58	GO:0006351	transcription, DNA-templated
0.44	GO:0034605	cellular response to heat
0.34	GO:0006744	ubiquinone biosynthetic process
0.34	GO:0035019	somatic stem cell population maintenance
0.34	GO:0060964	regulation of gene silencing by miRNA
0.34	GO:0008543	fibroblast growth factor receptor signaling pathway
0.34	GO:0016073	snRNA metabolic process
0.34	GO:0050434	positive regulation of viral transcription
0.34	GO:0006283	transcription-coupled nucleotide-excision repair
0.34	GO:0000398	mRNA splicing, via spliceosome

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.68	GO:0046983	protein dimerization activity
0.50	GO:0003677	DNA binding
0.33	GO:0030170	pyridoxal phosphate binding

0.54	GO:0005665	DNA-directed RNA polymerase II, core complex
0.47	GO:0005703	polytene chromosome puff
0.45	GO:0015630	microtubule cytoskeleton
0.44	GO:0005829	cytosol

0.70

GO:0003899

tr|O97365|O97365_DROME
BM-40
Search

0.84	Secreted protein acidic and rich in cysteine Ca binding region

0.61	GO:0007165	signal transduction
0.53	GO:0007504	larval fat body development
0.52	GO:0070278	extracellular matrix constituent secretion
0.52	GO:0061327	anterior Malpighian tubule development
0.52	GO:0030536	larval feeding behavior
0.51	GO:0070831	basement membrane assembly
0.51	GO:0007443	Malpighian tubule morphogenesis
0.51	GO:0060438	trachea development
0.49	GO:0007498	mesoderm development
0.36	GO:0007155	cell adhesion

0.84	GO:0050840	extracellular matrix binding
0.83	GO:0005518	collagen binding
0.70	GO:0005509	calcium ion binding
0.36	GO:0046982	protein heterodimerization activity
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.34	GO:0003677	DNA binding
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.76	GO:0005578	proteinaceous extracellular matrix
0.70	GO:0005615	extracellular space
0.36	GO:0000786	nucleosome
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

GO:0008138

sp|O97394|SDK_DROME
Protein sidekick
Search

0.86	Fibronectin type-III domain-containing protein 3A

0.32	GO:0042675	compound eye cone cell differentiation
0.31	GO:0046533	negative regulation of photoreceptor cell differentiation
0.31	GO:0050931	pigment cell differentiation
0.31	GO:0007155	cell adhesion

0.32	GO:0098595	perivitelline space
0.31	GO:0005887	integral component of plasma membrane

tr|O97418|O97418_DROME
EG:152A3.7 protein
Search

0.29	NADH dehydrogenase

0.69

GO:0042773

ATP synthesis coupled electron transport

0.69	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.36	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0032561	guanyl ribonucleotide binding
0.35	GO:0009055	electron transfer activity
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.44	GO:0045271	respiratory chain complex I
0.42	GO:0098798	mitochondrial protein complex
0.41	GO:1990204	oxidoreductase complex
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|O97420|U184_DROME
UPF0184 protein CG14818
Search

sp|O97422|B3GI_DROME
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase I
Search

0.76	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase I

0.74	GO:0006486	protein glycosylation
0.52	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process
0.47	GO:0030204	chondroitin sulfate metabolic process
0.46	GO:0015012	heparan sulfate proteoglycan biosynthetic process
0.42	GO:0051216	cartilage development
0.41	GO:0030198	extracellular matrix organization
0.40	GO:0050651	dermatan sulfate proteoglycan biosynthetic process
0.39	GO:0006024	glycosaminoglycan biosynthetic process
0.39	GO:0005975	carbohydrate metabolic process
0.38	GO:0090316	positive regulation of intracellular protein transport

0.85	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
0.54	GO:0046872	metal ion binding
0.39	GO:0072542	protein phosphatase activator activity
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.34	GO:0004824	lysine-tRNA ligase activity
0.34	GO:0004725	protein tyrosine phosphatase activity
0.32	GO:0003676	nucleic acid binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.74	GO:0000139	Golgi membrane
0.38	GO:0005801	cis-Golgi network
0.30	GO:0016021	integral component of membrane

0.85

EC:2.4.1.135

GO:0015018

tr|O97428|O97428_DROME
Ciboulot, isoform A
Search

0.90	Thymosin-repeated protein 1

0.75	GO:0007015	actin filament organization
0.42	GO:0035193	larval central nervous system remodeling
0.39	GO:0007420	brain development

0.85

GO:0003785

actin monomer binding

0.37

GO:0005829

cytosol

tr|O97454|O97454_DROME
GEO08125p1
Search

0.68	Cell cycle control protein cwf14

0.44	GO:2000825	positive regulation of androgen receptor activity
0.44	GO:0000398	mRNA splicing, via spliceosome

0.42	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.42	GO:0035257	nuclear hormone receptor binding
0.34	GO:0008430	selenium binding

0.61	GO:0005634	nucleus
0.40	GO:0030529	intracellular ribonucleoprotein complex
0.40	GO:0000785	chromatin
0.38	GO:0031974	membrane-enclosed lumen
0.38	GO:1902494	catalytic complex
0.30	GO:0031224	intrinsic component of membrane

sp|O97477|INO1_DROME
Inositol-3-phosphate synthase
Search

0.53	Myo-inositol phosphate synthase

0.82	GO:0006021	inositol biosynthetic process
0.68	GO:0008654	phospholipid biosynthetic process
0.40	GO:0001522	pseudouridine synthesis
0.39	GO:0042254	ribosome biogenesis
0.33	GO:0006468	protein phosphorylation
0.32	GO:0055114	oxidation-reduction process

0.83	GO:0004512	inositol-3-phosphate synthase activity
0.33	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.33	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.36	GO:0005737	cytoplasm
0.32	GO:0043231	intracellular membrane-bounded organelle

0.83	EC:5.5.1.4	GO:0004512
0.83	KEGG:R07324	GO:0004512

tr|O97479|O97479_DROME
FI05212p
Search

0.37	sorbitol dehydrogenase

0.53

GO:0055114

oxidation-reduction process

0.61	GO:0008270	zinc ion binding
0.52	GO:0016491	oxidoreductase activity

0.30

GO:0044425

membrane part

0.52

GO:0016491

sp|P00334|ADH_DROME
Alcohol dehydrogenase
Search

ADH

0.44	Alcohol dehydrogenase

0.72	GO:0006066	alcohol metabolic process
0.53	GO:0055114	oxidation-reduction process
0.37	GO:0006627	protein processing involved in protein targeting to mitochondrion
0.36	GO:1901616	organic hydroxy compound catabolic process
0.35	GO:0006117	acetaldehyde metabolic process
0.35	GO:0044282	small molecule catabolic process
0.35	GO:0048149	behavioral response to ethanol
0.33	GO:0017144	drug metabolic process
0.32	GO:0007165	signal transduction

0.80	GO:0004022	alcohol dehydrogenase (NAD) activity
0.35	GO:0004222	metalloendopeptidase activity
0.35	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.34	GO:0042803	protein homodimerization activity
0.33	GO:0046872	metal ion binding

0.34	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol
0.33	GO:0043234	protein complex

0.80

EC:1.1.1.1

GO:0004022

sp|P00399|COX1_DROME
Cytochrome c oxidase subunit 1
Search

COI

0.29	Cytochrome c oxidase subunit 1

0.64	GO:0006119	oxidative phosphorylation
0.64	GO:0009060	aerobic respiration
0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0020037	heme binding
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.63	GO:0005506	iron ion binding
0.62	GO:0009055	electron transfer activity

0.73	GO:0045277	respiratory chain complex IV
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.35	GO:0098798	mitochondrial protein complex
0.30	GO:0016021	integral component of membrane

0.65

GO:0016676

sp|P00408|COX2_DROME
Cytochrome c oxidase subunit 2
Search

MT:COII

0.40	Cytochrome c oxidase subunit 2

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.33	GO:0006119	oxidative phosphorylation
0.33	GO:0045333	cellular respiration

0.72	GO:0005507	copper ion binding
0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.34	GO:0098798	mitochondrial protein complex
0.33	GO:0070069	cytochrome complex
0.33	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.65

GO:0016676

sp|P00417|COX3_DROME
Cytochrome c oxidase subunit 3
Search

COX3

0.44	Cytochrome c oxidase subunit 3

0.76	GO:0019646	aerobic electron transport chain
0.63	GO:1902600	hydrogen ion transmembrane transport

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.61	GO:0005739	mitochondrion
0.34	GO:0019866	organelle inner membrane
0.30	GO:0044425	membrane part

0.65

GO:0016676

sp|P00522|ABL_DROME
Tyrosine-protein kinase Abl
Search

0.67	Tyrosine-protein kinase Abl

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.41	GO:0046777	protein autophosphorylation
0.41	GO:0007303	cytoplasmic transport, nurse cell to oocyte
0.41	GO:0021785	branchiomotor neuron axon guidance
0.41	GO:0007370	ventral furrow formation
0.41	GO:0072499	photoreceptor cell axon guidance
0.41	GO:0045087	innate immune response
0.41	GO:0016199	axon midline choice point recognition
0.41	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.41	GO:0007419	ventral cord development

0.81	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0005102	receptor binding
0.33	GO:0003723	RNA binding

0.41	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.41	GO:0005927	muscle tendon junction
0.40	GO:0045179	apical cortex
0.40	GO:0070938	contractile ring
0.39	GO:0030424	axon
0.38	GO:0005911	cell-cell junction
0.37	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0004715

sp|P00528|SRC64_DROME
Tyrosine-protein kinase Src64B
Search

0.57	Tyrosine-protein kinase

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.42	GO:0007166	cell surface receptor signaling pathway
0.42	GO:0002376	immune system process
0.42	GO:0046777	protein autophosphorylation
0.42	GO:0032024	positive regulation of insulin secretion
0.41	GO:0002764	immune response-regulating signaling pathway
0.41	GO:0016477	cell migration
0.40	GO:0050778	positive regulation of immune response
0.40	GO:0042127	regulation of cell proliferation
0.40	GO:0030154	cell differentiation

0.79	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0005102	receptor binding
0.36	GO:0071253	connexin binding
0.36	GO:0042169	SH2 domain binding
0.35	GO:0097110	scaffold protein binding
0.35	GO:0044325	ion channel binding

0.41	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.36	GO:0045172	germline ring canal
0.36	GO:0005829	cytosol
0.35	GO:0002102	podosome
0.35	GO:0032587	ruffle membrane
0.35	GO:0005901	caveola
0.35	GO:0005884	actin filament
0.35	GO:0005770	late endosome
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005764	lysosome

0.79

GO:0004715

sp|P00850|ATP6_DROME
ATP synthase subunit a
Search

ATP6

0.44	ATP synthase subunit a

0.67	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.66	GO:0006754	ATP biosynthetic process
0.35	GO:0070050	neuron cellular homeostasis
0.35	GO:0046716	muscle cell cellular homeostasis
0.35	GO:0008340	determination of adult lifespan
0.34	GO:0006839	mitochondrial transport
0.33	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.33	GO:0046907	intracellular transport
0.33	GO:0040011	locomotion

0.60	GO:0015078	hydrogen ion transmembrane transporter activity
0.34	GO:0036442	proton-exporting ATPase activity
0.34	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.34	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism

0.68	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.59	GO:0031966	mitochondrial membrane
0.59	GO:0019866	organelle inner membrane
0.34	GO:0098798	mitochondrial protein complex
0.30	GO:0016021	integral component of membrane

sp|P00967|PUR2_DROME
Trifunctional purine biosynthetic protein adenosine-3
Search

0.75	Trifunctional purine biosynthetic protein adenosine-3

0.73	GO:0009113	purine nucleobase biosynthetic process
0.69	GO:0006189	'de novo' IMP biosynthetic process
0.42	GO:0032259	methylation
0.36	GO:0003360	brainstem development
0.36	GO:0021549	cerebellum development
0.36	GO:0021987	cerebral cortex development
0.35	GO:0046654	tetrahydrofolate biosynthetic process
0.34	GO:0006544	glycine metabolic process
0.34	GO:0010035	response to inorganic substance
0.34	GO:0010033	response to organic substance

0.76	GO:0004637	phosphoribosylamine-glycine ligase activity
0.76	GO:0004641	phosphoribosylformylglycinamidine cyclo-ligase activity
0.73	GO:0004644	phosphoribosylglycinamide formyltransferase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.42	GO:0008168	methyltransferase activity

0.47	GO:0005737	cytoplasm
0.34	GO:0070062	extracellular exosome

0.76	EC:6.3.4.13	GO:0004637
0.76	KEGG:R04144	GO:0004637

sp|P02255|H1_DROME
Histone H1
Search

HIS1

0.97

Histone 1

0.79	GO:0006334	nucleosome assembly
0.35	GO:0031057	negative regulation of histone modification
0.35	GO:0006342	chromatin silencing

0.55	GO:0003677	DNA binding
0.40	GO:0003682	chromatin binding
0.37	GO:0046982	protein heterodimerization activity

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

sp|P02283|H2B_DROME
Histone H2B
Search

0.41	GO:0006334	nucleosome assembly
0.33	GO:0006352	DNA-templated transcription, initiation

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.42	GO:0031248	protein acetyltransferase complex
0.40	GO:0031974	membrane-enclosed lumen
0.38	GO:0043234	protein complex

sp|P02299|H3_DROME
Histone H3
Search

0.43	GO:0006334	nucleosome assembly
0.35	GO:0006352	DNA-templated transcription, initiation

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.39	GO:0031491	nucleosome binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.36	GO:0005700	polytene chromosome
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P02515|HSP22_DROME
Heat shock protein 22
Search

0.56	Small heat shock protein 4

0.70	GO:0061077	chaperone-mediated protein folding
0.69	GO:0008340	determination of adult lifespan
0.67	GO:0009408	response to heat
0.59	GO:0006979	response to oxidative stress
0.56	GO:0009631	cold acclimation
0.51	GO:0001666	response to hypoxia
0.50	GO:0042026	protein refolding
0.38	GO:0060047	heart contraction
0.38	GO:0030239	myofibril assembly
0.38	GO:0007519	skeletal muscle tissue development

0.64	GO:0051082	unfolded protein binding
0.61	GO:0042802	identical protein binding
0.59	GO:0005212	structural constituent of eye lens
0.40	GO:0017022	myosin binding
0.40	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.36	GO:0003779	actin binding
0.36	GO:0046872	metal ion binding

0.61	GO:0005759	mitochondrial matrix
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.40

EC:3.1.4.17

GO:0004114

sp|P02516|HSP23_DROME
Heat shock protein 23
Search

HSP23

0.88	Alpha crystallin

0.82	GO:0009631	cold acclimation
0.79	GO:0061077	chaperone-mediated protein folding
0.76	GO:0042026	protein refolding
0.75	GO:0009408	response to heat
0.70	GO:0008340	determination of adult lifespan
0.66	GO:0001666	response to hypoxia
0.61	GO:0042595	behavioral response to starvation
0.56	GO:0050832	defense response to fungus
0.54	GO:0042742	defense response to bacterium

0.71	GO:0051082	unfolded protein binding
0.61	GO:0017022	myosin binding
0.40	GO:0003779	actin binding

0.35	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm

sp|P02517|HSP26_DROME
Heat shock protein 26
Search

HSP27

0.80	Alpha crystallin

0.82	GO:0009631	cold acclimation
0.79	GO:0061077	chaperone-mediated protein folding
0.78	GO:0008340	determination of adult lifespan
0.76	GO:0042026	protein refolding
0.75	GO:0009408	response to heat
0.60	GO:0042595	behavioral response to starvation
0.56	GO:0050832	defense response to fungus
0.55	GO:0001666	response to hypoxia
0.53	GO:0042742	defense response to bacterium

0.71	GO:0051082	unfolded protein binding
0.71	GO:0017022	myosin binding
0.37	GO:0003779	actin binding

0.35	GO:0005737	cytoplasm
0.35	GO:0005634	nucleus

sp|P02518|HSP27_DROME
Heat shock protein 27
Search

HSP27

0.90	Heat shock protein 27

0.83	GO:0042595	behavioral response to starvation
0.79	GO:0061077	chaperone-mediated protein folding
0.78	GO:0008340	determination of adult lifespan
0.76	GO:0042026	protein refolding
0.75	GO:0009408	response to heat
0.75	GO:0050832	defense response to fungus
0.70	GO:0042742	defense response to bacterium
0.63	GO:0009631	cold acclimation
0.55	GO:0001666	response to hypoxia

0.71	GO:0051082	unfolded protein binding
0.45	GO:0017022	myosin binding
0.37	GO:0003779	actin binding

0.38	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

sp|P02572|ACT2_DROME
Actin-42A
Search

0.54	Cytoplasmic actin

0.43	GO:0000281	mitotic cytokinesis
0.34	GO:0007010	cytoskeleton organization

0.50	GO:0030554	adenyl nucleotide binding
0.50	GO:0097367	carbohydrate derivative binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005200	structural constituent of cytoskeleton

0.45	GO:0035060	brahma complex
0.40	GO:0097433	dense body
0.40	GO:0005856	cytoskeleton
0.39	GO:0005925	focal adhesion
0.35	GO:0005886	plasma membrane
0.34	GO:0099512	supramolecular fiber

sp|P02574|ACT4_DROME
Actin, larval muscle
Search

0.51	Actin, indirect flight muscle

0.47	GO:0098529	neuromuscular junction development, skeletal muscle fiber
0.44	GO:0043486	histone exchange
0.43	GO:0050807	regulation of synapse organization
0.43	GO:0000281	mitotic cytokinesis
0.42	GO:0016573	histone acetylation
0.40	GO:0071689	muscle thin filament assembly
0.39	GO:0014866	skeletal myofibril assembly
0.34	GO:0007507	heart development

0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005200	structural constituent of cytoskeleton

0.43	GO:0035267	NuA4 histone acetyltransferase complex
0.39	GO:0005856	cytoskeleton
0.36	GO:0099512	supramolecular fiber
0.34	GO:0005737	cytoplasm
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P02825|HSP71_DROME
Major heat shock 70 kDa protein Ab
Search

0.58	Major heat shock 70 kDa protein Bbb

0.43	GO:0008340	determination of adult lifespan
0.43	GO:0035080	heat shock-mediated polytene chromosome puffing
0.42	GO:0042594	response to starvation
0.40	GO:0001666	response to hypoxia
0.39	GO:0006986	response to unfolded protein
0.34	GO:0010918	positive regulation of mitochondrial membrane potential
0.34	GO:0070584	mitochondrion morphogenesis
0.34	GO:0000422	autophagy of mitochondrion
0.33	GO:0009636	response to toxic substance
0.33	GO:0006457	protein folding

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0051082	unfolded protein binding
0.33	GO:0043565	sequence-specific DNA binding

0.33

GO:0005739

mitochondrion

0.34

GO:0032440

sp|P02828|HSP83_DROME
Heat shock protein 83
Search

0.56	Heat shock proetein 90

0.69	GO:0006457	protein folding
0.62	GO:0006950	response to stress
0.50	GO:1901389	negative regulation of transforming growth factor beta activation
0.48	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.48	GO:1905323	telomerase holoenzyme complex assembly
0.47	GO:0071157	negative regulation of cell cycle arrest
0.47	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.47	GO:0032516	positive regulation of phosphoprotein phosphatase activity
0.47	GO:2000010	positive regulation of protein localization to cell surface
0.46	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

0.71	GO:0051082	unfolded protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.48	GO:0019904	protein domain specific binding
0.47	GO:0043008	ATP-dependent protein binding
0.47	GO:1990226	histone methyltransferase binding
0.46	GO:0070182	DNA polymerase binding
0.45	GO:0042826	histone deacetylase binding

0.47	GO:0034751	aryl hydrocarbon receptor complex
0.45	GO:0005705	polytene chromosome interband
0.44	GO:0008180	COP9 signalosome
0.43	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0005813	centrosome
0.41	GO:0005576	extracellular region
0.41	GO:0005829	cytosol
0.40	GO:0042470	melanosome
0.39	GO:1990917	ooplasm
0.38	GO:1990913	sperm head plasma membrane

0.34

GO:0016887

sp|P02833|ANTP_DROME
Homeotic protein antennapedia
Search

ANTP

0.88	Homeotic protein antennapedia

0.67	GO:0007275	multicellular organism development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.43	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
0.41	GO:0051254	positive regulation of RNA metabolic process
0.41	GO:0010557	positive regulation of macromolecule biosynthetic process
0.41	GO:0031328	positive regulation of cellular biosynthetic process
0.41	GO:0030154	cell differentiation
0.41	GO:0006366	transcription by RNA polymerase II

0.64	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.41	GO:0001012	RNA polymerase II regulatory region DNA binding
0.40	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.39	GO:0005829	cytosol
0.39	GO:0043233	organelle lumen
0.37	GO:0044446	intracellular organelle part
0.32	GO:0012505	endomembrane system
0.32	GO:0031090	organelle membrane
0.32	GO:0031975	envelope

sp|P02835|FTZ_DROME
Segmentation protein fushi tarazu
Search

FTZ

0.97	Segmentation protein fushi tarazu

0.65	GO:0007506	gonadal mesoderm development
0.62	GO:0008354	germ cell migration
0.60	GO:0035282	segmentation
0.57	GO:0000122	negative regulation of transcription by RNA polymerase II
0.56	GO:0006366	transcription by RNA polymerase II
0.55	GO:0045944	positive regulation of transcription by RNA polymerase II
0.42	GO:0009952	anterior/posterior pattern specification
0.41	GO:0009880	embryonic pattern specification
0.39	GO:0001708	cell fate specification
0.39	GO:0060322	head development

0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0035326	enhancer binding
0.61	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.59	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0001012	RNA polymerase II regulatory region DNA binding
0.54	GO:0003690	double-stranded DNA binding
0.36	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.33	GO:0043233	organelle lumen
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044446	intracellular organelle part

sp|P02836|HMEN_DROME
Segmentation polarity homeobox protein engrailed
Search

0.69	Segmentation polarity homeobox protein engrailed

0.69	GO:0007275	multicellular organism development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0048867	stem cell fate determination
0.56	GO:0010468	regulation of gene expression
0.53	GO:0043524	negative regulation of neuron apoptotic process
0.51	GO:0002009	morphogenesis of an epithelium
0.51	GO:0007548	sex differentiation
0.50	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.50	GO:0060322	head development

0.65	GO:0043565	sequence-specific DNA binding
0.53	GO:0035326	enhancer binding
0.52	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P02839|LCP1_DROME
Larval cuticle protein 1
Search

0.87	Larval cuticle protein 1

0.41	GO:0040003	chitin-based cuticle development
0.39	GO:0002168	instar larval development
0.39	GO:0007591	molting cycle, chitin-based cuticle
0.39	GO:0042381	hemolymph coagulation
0.32	GO:0035556	intracellular signal transduction

0.79

GO:0042302

structural constituent of cuticle

0.48	GO:0031012	extracellular matrix
0.31	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|P02840|SGS3_DROME
Salivary glue protein Sgs-3
Search

0.79	Salivary glue protein Sgs-3

0.86

GO:0071390

cellular response to ecdysone

0.82

GO:0005201

extracellular matrix structural constituent

0.74

GO:0031012

extracellular matrix

sp|P02841|SGS7_DROME
Salivary glue protein Sgs-7
Search

0.95	Salivary glue protein Sgs-7

0.64

GO:0071390

cellular response to ecdysone

0.66

GO:0005615

extracellular space

sp|P02842|SGS8_DROME
Salivary glue protein Sgs-8
Search

0.84	GO:0071390	cellular response to ecdysone
0.47	GO:0006284	base-excision repair
0.47	GO:0006289	nucleotide-excision repair

0.58	GO:0005201	extracellular matrix structural constituent
0.49	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity
0.49	GO:0140080	class III/IV DNA-(apurinic or apyrimidinic site) lyase activity
0.49	GO:0140078	class I DNA-(apurinic or apyrimidinic site) lyase activity
0.47	GO:0003684	damaged DNA binding
0.43	GO:0008270	zinc ion binding

0.54

GO:0031012

extracellular matrix

0.49

EC:3.2.2.23

GO:0008534

sp|P02843|VIT1_DROME
Vitellogenin-1
Search

YP1

0.82	Yolk polypeptide

0.41	GO:0045995	regulation of embryonic development
0.40	GO:0009792	embryo development ending in birth or egg hatching
0.40	GO:0009617	response to bacterium
0.35	GO:0007548	sex differentiation

0.70

GO:0052689

carboxylic ester hydrolase activity

0.66	GO:0005576	extracellular region
0.42	GO:0043186	P granule
0.30	GO:0031224	intrinsic component of membrane

0.70	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.70	KEGG:R00630	GO:0052689

sp|P02844|VIT2_DROME
Vitellogenin-2
Search

0.56	Yolk protein D

0.36	GO:0032502	developmental process
0.36	GO:0045995	regulation of embryonic development
0.35	GO:0009617	response to bacterium
0.35	GO:0022414	reproductive process
0.34	GO:0032501	multicellular organismal process

0.70

GO:0052689

carboxylic ester hydrolase activity

0.66	GO:0005576	extracellular region
0.37	GO:0016590	ACF complex
0.36	GO:0043186	P granule

0.70	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.70	KEGG:R00630	GO:0052689

sp|P03896|NU2M_DROME
NADH-ubiquinone oxidoreductase chain 2
Search

ND2

0.42	NADH-ubiquinone oxidoreductase chain 2

0.74

GO:0006120

mitochondrial electron transport, NADH to ubiquinone

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.34	GO:0030964	NADH dehydrogenase complex
0.34	GO:0098798	mitochondrial protein complex
0.34	GO:1990204	oxidoreductase complex
0.33	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.69

GO:0008137

sp|P04052|RPB1_DROME
DNA-directed RNA polymerase II subunit RPB1
Search

RPB1

0.48	DNA-directed RNA polymerase subunit

0.72

GO:0006366

transcription by RNA polymerase II

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.55	GO:0003677	DNA binding
0.31	GO:0046872	metal ion binding

0.78	GO:0005665	DNA-directed RNA polymerase II, core complex
0.39	GO:0005703	polytene chromosome puff
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0003899

sp|P04197|MYB_DROME
Myb protein
Search

0.54	GO:0090282	positive regulation of transcription involved in G2/M transition of mitotic cell cycle
0.54	GO:0007307	eggshell chorion gene amplification
0.52	GO:0045792	negative regulation of cell size
0.51	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
0.51	GO:0007099	centriole replication
0.50	GO:0007030	Golgi organization
0.49	GO:0000281	mitotic cytokinesis
0.49	GO:0033043	regulation of organelle organization
0.49	GO:0007051	spindle organization
0.49	GO:0008283	cell proliferation

0.55	GO:0003677	DNA binding
0.50	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.44	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.33	GO:0005515	protein binding
0.33	GO:0008270	zinc ion binding

0.53	GO:0031523	Myb complex
0.51	GO:0005719	nuclear euchromatin
0.51	GO:0005700	polytene chromosome
0.34	GO:0016363	nuclear matrix
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

sp|P04357|MT1_DROME
Metallothionein-1
Search

MTNA

0.81	Metallothionein A

0.63	GO:0010038	response to metal ion
0.61	GO:0055065	metal ion homeostasis
0.35	GO:0055085	transmembrane transport

0.52	GO:0046872	metal ion binding
0.38	GO:0015267	channel activity

0.49	GO:0005854	nascent polypeptide-associated complex
0.30	GO:0016021	integral component of membrane

sp|P04359|RL32_DROME
60S ribosomal protein L32
Search

RPL32

0.46	Ribosomal protein L32

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process

0.64

GO:0003735

structural constituent of ribosome

0.61	GO:0005840	ribosome
0.48	GO:0000228	nuclear chromosome
0.48	GO:0005730	nucleolus
0.34	GO:0044445	cytosolic part
0.30	GO:0031224	intrinsic component of membrane

sp|P04388|RAS2_DROME
Ras-like protein 2
Search

0.62	Ras oncogene

0.61	GO:0007165	signal transduction
0.44	GO:1901214	regulation of neuron death
0.44	GO:0030335	positive regulation of cell migration
0.36	GO:0001649	osteoblast differentiation
0.34	GO:0008284	positive regulation of cell proliferation
0.34	GO:0045199	maintenance of epithelial cell apical/basal polarity

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity

0.35	GO:0005925	focal adhesion
0.35	GO:0070062	extracellular exosome
0.35	GO:0005622	intracellular
0.34	GO:0005886	plasma membrane
0.33	GO:0012505	endomembrane system
0.30	GO:0016021	integral component of membrane

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

sp|P04412|EGFR_DROME
Epidermal growth factor receptor
Search

EGFR

0.65	Receptor protein-tyrosine kinase

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.70	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.59	GO:0023014	signal transduction by protein phosphorylation
0.56	GO:0035556	intracellular signal transduction
0.43	GO:0008071	maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded
0.42	GO:0035310	notum cell fate specification
0.42	GO:0046673	negative regulation of compound eye retinal cell programmed cell death
0.42	GO:0007395	dorsal closure, spreading of leading edge cells
0.42	GO:0016330	second mitotic wave involved in compound eye morphogenesis
0.42	GO:0007479	leg disc proximal/distal pattern formation

0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.75	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding

0.42	GO:0035230	cytoneme
0.42	GO:0005622	intracellular
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.80

GO:0004714

sp|P04657|CYC1_DROME
Cytochrome c-1
Search

0.38	Mitochondrial cytochrome C

0.61	GO:0022900	electron transport chain
0.48	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.46	GO:0046669	regulation of compound eye retinal cell programmed cell death
0.46	GO:0007291	sperm individualization
0.38	GO:0006119	oxidative phosphorylation
0.37	GO:0009060	aerobic respiration
0.37	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.36	GO:0042743	hydrogen peroxide metabolic process
0.35	GO:0006518	peptide metabolic process
0.35	GO:0043604	amide biosynthetic process

0.63	GO:0020037	heme binding
0.62	GO:0009055	electron transfer activity
0.53	GO:0046872	metal ion binding
0.35	GO:0003735	structural constituent of ribosome
0.33	GO:0008176	tRNA (guanine-N7-)-methyltransferase activity
0.33	GO:0000049	tRNA binding

0.61	GO:0070469	respiratory chain
0.59	GO:0005739	mitochondrion
0.43	GO:0031970	organelle envelope lumen
0.41	GO:0005829	cytosol
0.35	GO:0005840	ribosome
0.33	GO:0005634	nucleus
0.33	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.1.1.33

GO:0008176

sp|P04755|ACH3_DROME
Acetylcholine receptor subunit beta-like 1
Search

0.91	Nicotinic acetylcholine receptor beta subunit

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.47	GO:0007271	synaptic transmission, cholinergic

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.32	GO:0008146	sulfotransferase activity

0.78	GO:0045211	postsynaptic membrane
0.73	GO:0030054	cell junction
0.35	GO:0005892	acetylcholine-gated channel complex

0.32

EC:2.8.2

GO:0008146

sp|P04814|TRYA_DROME
Trypsin alpha
Search

0.46	Dvtry-1 trypsin precusor

0.61	GO:0006508	proteolysis
0.37	GO:0007596	blood coagulation

0.69	GO:0004252	serine-type endopeptidase activity
0.35	GO:0005509	calcium ion binding

0.43	GO:0005615	extracellular space
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004252

sp|P04950|OPS3_DROME
Opsin Rh3
Search

0.78	Ultraviolet wavelength sensitive opsin

0.79	GO:0007602	phototransduction
0.78	GO:0007601	visual perception
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.67	GO:0018298	protein-chromophore linkage
0.56	GO:0009589	detection of UV
0.52	GO:0034644	cellular response to UV
0.51	GO:0009584	detection of visible light
0.50	GO:0016039	absorption of UV light

0.72	GO:0004930	G-protein coupled receptor activity
0.71	GO:0009881	photoreceptor activity

0.30

GO:0044425

membrane part

sp|P05031|DDC_DROME
Aromatic-L-amino-acid decarboxylase
Search

DDC

0.55	Aromatic-L-amino-acid decarboxylase

0.60	GO:0006520	cellular amino acid metabolic process
0.56	GO:0007615	anesthesia-resistant memory
0.55	GO:0048082	regulation of adult chitin-containing cuticle pigmentation
0.55	GO:0043052	thermotaxis
0.55	GO:0040040	thermosensory behavior
0.55	GO:0042416	dopamine biosynthetic process
0.54	GO:0048085	adult chitin-containing cuticle pigmentation
0.54	GO:0042427	serotonin biosynthetic process
0.53	GO:0007616	long-term memory
0.52	GO:0035220	wing disc development

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding

0.30

GO:0016020

membrane

0.68

EC:4.1.1

GO:0016831

sp|P05049|SNAK_DROME
Serine protease snake
Search

0.49	Serine protease snake

0.61	GO:0006508	proteolysis
0.53	GO:0008063	Toll signaling pathway
0.47	GO:0051604	protein maturation
0.39	GO:0007311	maternal specification of dorsal/ventral axis, oocyte, germ-line encoded
0.34	GO:0051103	DNA ligation involved in DNA repair
0.33	GO:0016310	phosphorylation
0.33	GO:0071897	DNA biosynthetic process
0.33	GO:0006260	DNA replication
0.33	GO:0006310	DNA recombination

0.69	GO:0004252	serine-type endopeptidase activity
0.33	GO:0003910	DNA ligase (ATP) activity
0.33	GO:0016301	kinase activity
0.33	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005576	extracellular region
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P05084|HUNB_DROME
Protein hunchback
Search

0.70

Hunchback

0.61	GO:0044324	regulation of transcription involved in anterior/posterior axis specification
0.60	GO:0007400	neuroblast fate determination
0.60	GO:0007362	terminal region determination
0.60	GO:0008293	torso signaling pathway
0.53	GO:0000122	negative regulation of transcription by RNA polymerase II
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.47	GO:0040034	regulation of development, heterochronic
0.39	GO:0007355	anterior region determination
0.39	GO:0007402	ganglion mother cell fate determination
0.39	GO:0035289	posterior head segmentation

0.58	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.57	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.37	GO:0046872	metal ion binding

0.40

GO:0005634

nucleus

sp|P05130|KPC1_DROME
Protein kinase C, brain isozyme
Search

0.75	Protein kinase C, brain isozyme

0.63	GO:0006468	protein phosphorylation
0.60	GO:0035556	intracellular signal transduction
0.47	GO:2000370	positive regulation of clathrin-dependent endocytosis
0.47	GO:0035206	regulation of hemocyte proliferation
0.38	GO:0018209	peptidyl-serine modification
0.32	GO:0018212	peptidyl-tyrosine modification

0.83	GO:0004697	protein kinase C activity
0.62	GO:0008270	zinc ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.33	GO:0004713	protein tyrosine kinase activity

0.44	GO:0005622	intracellular
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.83

EC:2.7.11.13

GO:0004697

sp|P05205|HP1_DROME
Heterochromatin protein 1
Search

0.87	Heterochromatin protein 1

0.64	GO:1905644	regulation of FACT complex assembly
0.64	GO:1905632	protein localization to euchromatin
0.64	GO:0033697	positive regulation of extent of heterochromatin assembly
0.62	GO:0045892	negative regulation of transcription, DNA-templated
0.62	GO:0044026	DNA hypermethylation
0.62	GO:0090309	positive regulation of methylation-dependent chromatin silencing
0.61	GO:1900111	positive regulation of histone H3-K9 dimethylation
0.60	GO:1905634	regulation of protein localization to chromatin
0.60	GO:0031507	heterochromatin assembly
0.60	GO:0034773	histone H4-K20 trimethylation

0.61	GO:0099122	RNA polymerase II C-terminal domain binding
0.61	GO:0003696	satellite DNA binding
0.59	GO:0030544	Hsp70 protein binding
0.59	GO:0000182	rDNA binding
0.56	GO:0030674	protein binding, bridging
0.55	GO:0003682	chromatin binding
0.45	GO:0003723	RNA binding
0.38	GO:1990226	histone methyltransferase binding
0.38	GO:0035064	methylated histone binding
0.36	GO:0019904	protein domain specific binding

0.73	GO:0000791	euchromatin
0.65	GO:0000790	nuclear chromatin
0.61	GO:0035012	polytene chromosome, telomeric region
0.61	GO:0010369	chromocenter
0.61	GO:0005704	polytene chromosome band
0.60	GO:0005703	polytene chromosome puff
0.60	GO:0005705	polytene chromosome interband
0.59	GO:0000792	heterochromatin
0.56	GO:0000780	condensed nuclear chromosome, centromeric region
0.36	GO:0005819	spindle

0.33

GO:0018024

sp|P05303|EF1A2_DROME
Elongation factor 1-alpha 2
Search

0.44	Elongation factor 1-alpha

0.70

GO:0006414

translational elongation

0.71	GO:0003746	translation elongation factor activity
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005737	cytoplasm
0.33	GO:0043234	protein complex
0.33	GO:0043231	intracellular membrane-bounded organelle

sp|P05389|RLA2_DROME
60S acidic ribosomal protein P2
Search

0.69	Ribosomal protein LP2

0.69	GO:0006414	translational elongation
0.38	GO:0002181	cytoplasmic translation
0.37	GO:0042254	ribosome biogenesis
0.32	GO:0008213	protein alkylation
0.32	GO:0043414	macromolecule methylation

0.63	GO:0003735	structural constituent of ribosome
0.32	GO:0008168	methyltransferase activity

0.61	GO:0005840	ribosome
0.40	GO:0044445	cytosolic part
0.36	GO:0044446	intracellular organelle part

0.32

GO:0008168

sp|P05527|HMIN_DROME
Homeobox protein invected
Search

0.55	Homeobox protein invected

0.69	GO:0007275	multicellular organism development
0.62	GO:0048867	stem cell fate determination
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0002009	morphogenesis of an epithelium
0.56	GO:0050832	defense response to fungus
0.41	GO:0043524	negative regulation of neuron apoptotic process
0.41	GO:0007548	sex differentiation
0.40	GO:0120039	plasma membrane bounded cell projection morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.42	GO:0035326	enhancer binding
0.41	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0001012	RNA polymerase II regulatory region DNA binding
0.39	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P05552|ADF1_DROME
Transcription factor Adf-1
Search

ADF1

0.70	Alcohol dehydrogenase transcription factor

0.60	GO:0007416	synapse assembly
0.60	GO:0007613	memory
0.60	GO:0050773	regulation of dendrite development
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:1902680	positive regulation of RNA biosynthetic process
0.39	GO:0008355	olfactory learning
0.39	GO:0008345	larval locomotory behavior

0.59	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0003677	DNA binding
0.34	GO:0016798	hydrolase activity, acting on glycosyl bonds
0.32	GO:0004222	metalloendopeptidase activity
0.32	GO:0046872	metal ion binding

0.62	GO:0005705	polytene chromosome interband
0.61	GO:0005634	nucleus
0.33	GO:0017087	mitochondrial processing peptidase complex
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.2

GO:0016798

sp|P05623|A70A_DROME
Accessory gland-specific peptide 70A
Search

ACP70A

0.97	Sex peptide

0.87	GO:0046008	regulation of female receptivity, post-mating
0.76	GO:0010469	regulation of receptor activity
0.53	GO:0007621	negative regulation of female receptivity
0.52	GO:0018991	oviposition
0.48	GO:0046662	regulation of oviposition
0.48	GO:0007556	regulation of juvenile hormone metabolic process
0.47	GO:0006718	juvenile hormone biosynthetic process
0.47	GO:0045297	post-mating behavior
0.45	GO:0008343	adult feeding behavior
0.45	GO:0007186	G-protein coupled receptor signaling pathway

0.79	GO:0005179	hormone activity
0.48	GO:0001664	G-protein coupled receptor binding

0.66

GO:0005576

extracellular region

sp|P05661|MYSA_DROME
Myosin heavy chain, muscle
Search

MHC

0.93	Myosin heavy chain, muscle

0.74	GO:0007018	microtubule-based movement
0.35	GO:0071689	muscle thin filament assembly
0.35	GO:0030241	skeletal muscle myosin thick filament assembly
0.35	GO:0060361	flight
0.35	GO:0007527	adult somatic muscle development
0.35	GO:0007427	epithelial cell migration, open tracheal system
0.35	GO:0007298	border follicle cell migration
0.34	GO:0045214	sarcomere organization
0.34	GO:0006936	muscle contraction
0.34	GO:0007517	muscle organ development

0.78	GO:0051015	actin filament binding
0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0016887	ATPase activity
0.35	GO:0008307	structural constituent of muscle
0.34	GO:0005516	calmodulin binding
0.34	GO:0042803	protein homodimerization activity

0.77	GO:0016459	myosin complex
0.35	GO:0005703	polytene chromosome puff
0.35	GO:0031672	A band

0.37

GO:0016887

sp|P05709|SIM_DROME
Protein single-minded
Search

0.78	Single-minded

0.57	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0035225	determination of genital disc primordium
0.54	GO:0007418	ventral midline development
0.53	GO:0007419	ventral cord development
0.52	GO:0007628	adult walking behavior
0.50	GO:0007411	axon guidance
0.49	GO:0007420	brain development

0.68	GO:0046983	protein dimerization activity
0.60	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.33	GO:0003887	DNA-directed DNA polymerase activity
0.32	GO:0000293	ferric-chelate reductase activity
0.32	GO:0000287	magnesium ion binding
0.32	GO:0015238	drug transmembrane transporter activity
0.32	GO:0015297	antiporter activity
0.31	GO:0030554	adenyl nucleotide binding

0.69	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.32	GO:0009360	DNA polymerase III complex
0.30	GO:0016020	membrane

0.33

GO:0003887

sp|P05812|HSP6A_DROME
Heat shock protein 67B1
Search

0.66	Heat shock protein 27

0.72	GO:0009408	response to heat
0.55	GO:0042026	protein refolding
0.48	GO:0000380	alternative mRNA splicing, via spliceosome
0.47	GO:0007530	sex determination
0.46	GO:0061077	chaperone-mediated protein folding

0.44	GO:0051082	unfolded protein binding
0.39	GO:0003723	RNA binding
0.39	GO:0005212	structural constituent of eye lens

0.30

GO:0031224

intrinsic component of membrane

sp|P05990|PYR1_DROME
CAD protein
Search

0.20	Carbamoyl-phosphate synthase large chain

0.70	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process
0.66	GO:0006541	glutamine metabolic process
0.38	GO:0000050	urea cycle
0.36	GO:0006526	arginine biosynthetic process
0.35	GO:0021644	vagus nerve morphogenesis
0.35	GO:0021615	glossopharyngeal nerve morphogenesis
0.35	GO:0044205	'de novo' UMP biosynthetic process
0.35	GO:0021636	trigeminal nerve morphogenesis
0.35	GO:0021610	facial nerve morphogenesis
0.35	GO:1900746	regulation of vascular endothelial growth factor signaling pathway

0.72	GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
0.64	GO:0004070	aspartate carbamoyltransferase activity
0.61	GO:0016597	amino acid binding
0.61	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.39	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity
0.36	GO:0004565	beta-galactosidase activity

0.33

GO:0005737

cytoplasm

0.72	EC:6.3.5.5	GO:0004088
0.64	KEGG:R01397	GO:0004070

sp|P06002|OPS1_DROME
Opsin Rh1
Search

0.49	Long wavelength sensitive opsin

0.76	GO:0007602	phototransduction
0.74	GO:0007601	visual perception
0.71	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.53	GO:0046673	negative regulation of compound eye retinal cell programmed cell death
0.53	GO:0009589	detection of UV
0.53	GO:0071632	optomotor response
0.52	GO:0009584	detection of visible light
0.52	GO:0043052	thermotaxis
0.52	GO:0042331	phototaxis

0.76	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005515	protein binding

0.53	GO:0016029	subrhabdomeral cisterna
0.52	GO:0016027	inaD signaling complex
0.51	GO:0005767	secondary lysosome
0.50	GO:0097038	perinuclear endoplasmic reticulum
0.50	GO:0005771	multivesicular body
0.49	GO:0005791	rough endoplasmic reticulum
0.48	GO:0005769	early endosome
0.30	GO:0016021	integral component of membrane

sp|P06601|PRD_DROME
Segmentation protein paired
Search

0.72	Segmentation protein paired

0.70	GO:0007275	multicellular organism development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:1902680	positive regulation of RNA biosynthetic process
0.41	GO:0060025	regulation of synaptic activity
0.39	GO:0007268	chemical synaptic transmission
0.38	GO:0030154	cell differentiation
0.38	GO:0009653	anatomical structure morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.56	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding
0.34	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm

0.34

GO:0004000

sp|P06602|EVE_DROME
Segmentation protein even-skipped
Search

EVE

0.94	Pair-rule transcription factor even-skipped

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0007376	cephalic furrow formation
0.54	GO:0009997	negative regulation of cardioblast cell fate specification
0.54	GO:0007377	germ-band extension
0.53	GO:0007512	adult heart development
0.53	GO:1901739	regulation of myoblast fusion
0.52	GO:0008045	motor neuron axon guidance
0.50	GO:0050770	regulation of axonogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.51	GO:0035326	enhancer binding
0.51	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.39	GO:0043233	organelle lumen
0.37	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P06603|TBA1_DROME
Tubulin alpha-1 chain
Search

0.53	Tubulin alpha chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.43	GO:1903047	mitotic cell cycle process
0.43	GO:0019730	antimicrobial humoral response
0.42	GO:0071173	spindle assembly checkpoint
0.42	GO:0045841	negative regulation of mitotic metaphase/anaphase transition
0.39	GO:0061640	cytoskeleton-dependent cytokinesis
0.32	GO:0055085	transmembrane transport

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0017022	myosin binding
0.33	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding

0.73	GO:0005874	microtubule
0.47	GO:0005737	cytoplasm
0.43	GO:0005818	aster
0.41	GO:0005813	centrosome
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P06604|TBA2_DROME
Tubulin alpha-2 chain
Search

0.53	Tubulin alpha chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.43	GO:0007094	mitotic spindle assembly checkpoint
0.36	GO:0019730	antimicrobial humoral response

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0019901	protein kinase binding

0.73	GO:0005874	microtubule
0.45	GO:0005737	cytoplasm
0.36	GO:0005818	aster
0.35	GO:0005813	centrosome

sp|P06605|TBA3_DROME
Tubulin alpha-3 chain
Search

0.53	Tubulin alpha chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.41	GO:1903047	mitotic cell cycle process
0.40	GO:0019730	antimicrobial humoral response
0.40	GO:0071173	spindle assembly checkpoint
0.39	GO:0045841	negative regulation of mitotic metaphase/anaphase transition
0.39	GO:0061640	cytoskeleton-dependent cytokinesis
0.32	GO:0055085	transmembrane transport

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0017022	myosin binding
0.33	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding

0.73	GO:0005874	microtubule
0.47	GO:0005737	cytoplasm
0.40	GO:0005818	aster
0.39	GO:0005813	centrosome
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P06606|TBA4_DROME
Tubulin alpha-4 chain
Search

0.53	Tubulin alpha chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.48	GO:0035046	pronuclear migration
0.48	GO:0035038	female pronucleus assembly
0.48	GO:0040016	embryonic cleavage
0.46	GO:0007422	peripheral nervous system development
0.45	GO:0000280	nuclear division
0.44	GO:1903047	mitotic cell cycle process
0.44	GO:0009792	embryo development ending in birth or egg hatching
0.44	GO:0007417	central nervous system development

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004421	hydroxymethylglutaryl-CoA synthase activity
0.33	GO:0005515	protein binding

0.73	GO:0005874	microtubule
0.48	GO:0005737	cytoplasm
0.40	GO:0045298	tubulin complex
0.38	GO:0005816	spindle pole body
0.37	GO:0071944	cell periphery
0.36	GO:0005819	spindle
0.35	GO:0034399	nuclear periphery
0.30	GO:0016020	membrane

0.34	EC:2.3.3.10	GO:0004421
0.34	KEGG:R01978	GO:0004421

sp|P06607|VIT3_DROME
Vitellogenin-3
Search

YP1

0.80	Vitellogenin-3

0.51	GO:0045995	regulation of embryonic development
0.49	GO:0009792	embryo development ending in birth or egg hatching
0.48	GO:0009617	response to bacterium
0.37	GO:0007548	sex differentiation

0.69

GO:0052689

carboxylic ester hydrolase activity

0.65	GO:0005576	extracellular region
0.52	GO:0043186	P granule
0.36	GO:0016590	ACF complex

0.69	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.69	KEGG:R00630	GO:0052689

sp|P06742|MLC1_DROME
Myosin light chain alkali
Search

MLC1

0.87	Myosin light chain alkali

0.48	GO:0007498	mesoderm development
0.35	GO:0006936	muscle contraction

0.69	GO:0005509	calcium ion binding
0.36	GO:0000146	microfilament motor activity
0.33	GO:0015631	tubulin binding

0.51	GO:0005859	muscle myosin complex
0.34	GO:0005829	cytosol
0.33	GO:0005874	microtubule
0.30	GO:0044425	membrane part

sp|P07140|ACES_DROME
Acetylcholinesterase
Search

0.40	Ace-orthologous acetylcholinesterase

0.86	GO:0001507	acetylcholine catabolic process in synaptic cleft
0.49	GO:0042331	phototaxis
0.48	GO:0042426	choline catabolic process

0.86	GO:0003990	acetylcholinesterase activity
0.50	GO:0043199	sulfate binding
0.44	GO:0042803	protein homodimerization activity

0.85	GO:0043083	synaptic cleft
0.39	GO:0005886	plasma membrane
0.37	GO:0031225	anchored component of membrane
0.37	GO:0030054	cell junction
0.36	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.86

EC:3.1.1.7

GO:0003990

sp|P07182|CH36_DROME
Chorion protein S36
Search

CP36

0.97	Chorion protein 36

0.86	GO:0007305	vitelline membrane formation involved in chorion-containing eggshell formation
0.85	GO:0007306	eggshell chorion assembly

0.86

GO:0005213

structural constituent of chorion

0.85	GO:0042600	chorion
0.43	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|P07183|CH38_DROME
Chorion protein S38
Search

CP38

0.97	Chorion protein 38, isoform B

0.46	GO:0006812	cation transport
0.44	GO:0044267	cellular protein metabolic process
0.44	GO:0036211	protein modification process
0.42	GO:0034220	ion transmembrane transport
0.42	GO:0099131	ATP hydrolysis coupled ion transmembrane transport
0.39	GO:0006518	peptide metabolic process
0.39	GO:0043604	amide biosynthetic process
0.39	GO:0042665	regulation of ectodermal cell fate specification
0.39	GO:0060803	BMP signaling pathway involved in mesodermal cell fate specification
0.38	GO:0070488	neutrophil aggregation

0.46	GO:0008324	cation transmembrane transporter activity
0.44	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.43	GO:0042625	ATPase coupled ion transmembrane transporter activity
0.43	GO:0003746	translation elongation factor activity
0.40	GO:0043130	ubiquitin binding
0.40	GO:0030554	adenyl nucleotide binding
0.39	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0008144	drug binding

0.47	GO:0005853	eukaryotic translation elongation factor 1 complex
0.38	GO:0005886	plasma membrane
0.37	GO:0043229	intracellular organelle
0.37	GO:0043227	membrane-bounded organelle
0.36	GO:0030054	cell junction
0.36	GO:0009295	nucleoid
0.36	GO:0043228	non-membrane-bounded organelle
0.36	GO:0005615	extracellular space
0.35	GO:0044422	organelle part
0.35	GO:0005829	cytosol

0.44	EC:5.2.1.8	GO:0003755
0.39	KEGG:R03876	GO:0004842

sp|P07184|CH18_DROME
Chorion protein S18
Search

0.69	GO:0007275	multicellular organism development
0.34	GO:0002183	cytoplasmic translational initiation
0.34	GO:0031047	gene silencing by RNA

0.45	GO:0005213	structural constituent of chorion
0.34	GO:0003743	translation initiation factor activity
0.33	GO:0004386	helicase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.85	GO:0042600	chorion
0.44	GO:0005576	extracellular region
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P07185|CH15_DROME
Chorion protein S15
Search

CP15

0.97	Chorion protein 15

0.68	GO:0007275	multicellular organism development
0.37	GO:0016560	protein import into peroxisome matrix, docking

0.36

GO:0003723

RNA binding

0.85	GO:0042600	chorion
0.44	GO:0005576	extracellular region
0.36	GO:0042579	microbody
0.30	GO:0044425	membrane part

sp|P07186|CH19_DROME
Chorion protein S19
Search

CP19

0.97	Chorion protein 19

0.65	GO:0007275	multicellular organism development
0.50	GO:0055078	sodium ion homeostasis
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.43	GO:0010468	regulation of gene expression

0.48	GO:0005509	calcium ion binding
0.33	GO:0003723	RNA binding

0.80	GO:0042600	chorion
0.45	GO:0005576	extracellular region
0.43	GO:0005829	cytosol
0.41	GO:0005634	nucleus

sp|P07187|LCP2_DROME
Larval cuticle protein 2
Search

0.70	Larval cuticle protein 2

0.41	GO:0040003	chitin-based cuticle development
0.39	GO:0002168	instar larval development
0.39	GO:0007591	molting cycle, chitin-based cuticle
0.39	GO:0042381	hemolymph coagulation
0.32	GO:0035556	intracellular signal transduction

0.79

GO:0042302

structural constituent of cuticle

0.48	GO:0031012	extracellular matrix
0.31	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|P07188|LCP3_DROME
Larval cuticle protein 3
Search

0.89	Endocuticle structural glycoprotein SgAbd-3

0.43	GO:0040003	chitin-based cuticle development
0.37	GO:0002168	instar larval development
0.37	GO:0007591	molting cycle, chitin-based cuticle

0.79

GO:0042302

structural constituent of cuticle

0.49	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

sp|P07189|LCP4_DROME
Larval cuticle protein 4
Search

0.96	Larval cuticle protein III/IV

0.42	GO:0040003	chitin-based cuticle development
0.38	GO:0002168	instar larval development
0.38	GO:0007591	molting cycle, chitin-based cuticle

0.79

GO:0042302

structural constituent of cuticle

0.48	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

sp|P07190|MAL1_DROME
Maltase A1
Search

0.35	Alpha amylase

0.60	GO:0005975	carbohydrate metabolic process
0.37	GO:0006428	isoleucyl-tRNA aminoacylation
0.37	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity

0.39	GO:0032450	maltose alpha-glucosidase activity
0.39	GO:0004558	alpha-1,4-glucosidase activity
0.37	GO:0004822	isoleucine-tRNA ligase activity
0.37	GO:0002161	aminoacyl-tRNA editing activity
0.36	GO:0000049	tRNA binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.39	EC:3.2.1.20	GO:0032450
0.37	KEGG:R03656	GO:0004822

sp|P07191|MAL2_DROME
Maltase A2
Search

0.35	Alpha amylase

0.60	GO:0005975	carbohydrate metabolic process
0.30	GO:0009987	cellular process

0.41	GO:0032450	maltose alpha-glucosidase activity
0.40	GO:0004558	alpha-1,4-glucosidase activity
0.33	GO:0008146	sulfotransferase activity

0.30

GO:0031224

intrinsic component of membrane

0.41

EC:3.2.1.20

GO:0032450

sp|P07192|MAL3_DROME
Maltase A3
Search

0.27	Alpha amylase

0.60	GO:0005975	carbohydrate metabolic process
0.34	GO:0006428	isoleucyl-tRNA aminoacylation
0.33	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.32	GO:0055114	oxidation-reduction process

0.40	GO:0032450	maltose alpha-glucosidase activity
0.40	GO:0004558	alpha-1,4-glucosidase activity
0.34	GO:0103025	alpha-amylase activity (releasing maltohexaose)
0.34	GO:0004822	isoleucine-tRNA ligase activity
0.34	GO:0004556	alpha-amylase activity
0.33	GO:0002161	aminoacyl-tRNA editing activity
0.33	GO:0000049	tRNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.40	EC:3.2.1.20	GO:0032450
0.34	KEGG:R03656	GO:0004822

sp|P07207|NOTCH_DROME
Neurogenic locus Notch protein
Search

0.11

Notch

0.80	GO:0007219	Notch signaling pathway
0.71	GO:0030154	cell differentiation
0.69	GO:0007275	multicellular organism development
0.67	GO:0050793	regulation of developmental process
0.51	GO:0035172	hemocyte proliferation
0.51	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin
0.51	GO:0060250	germ-line stem-cell niche homeostasis
0.51	GO:0002213	defense response to insect
0.51	GO:0009608	response to symbiont
0.50	GO:0043697	cell dedifferentiation

0.68	GO:0005509	calcium ion binding
0.46	GO:0003682	chromatin binding
0.39	GO:0005044	scavenger receptor activity
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.32	GO:0003677	DNA binding
0.32	GO:0016787	hydrolase activity
0.31	GO:0005515	protein binding

0.50	GO:0035003	subapical complex
0.47	GO:0030139	endocytic vesicle
0.47	GO:0005770	late endosome
0.47	GO:0005912	adherens junction
0.46	GO:0005764	lysosome
0.45	GO:0009986	cell surface
0.41	GO:0005634	nucleus
0.40	GO:0043234	protein complex
0.32	GO:0005796	Golgi lumen
0.32	GO:0005788	endoplasmic reticulum lumen

0.34

GO:0032440

sp|P07247|KRUP_DROME
Protein krueppel
Search

0.30

Kruepple

0.60	GO:0061332	Malpighian tubule bud morphogenesis
0.58	GO:0007400	neuroblast fate determination
0.57	GO:0035206	regulation of hemocyte proliferation
0.55	GO:0048749	compound eye development
0.53	GO:0007411	axon guidance
0.53	GO:0006342	chromatin silencing
0.52	GO:0000122	negative regulation of transcription by RNA polymerase II
0.41	GO:0035282	segmentation
0.39	GO:0007402	ganglion mother cell fate determination
0.38	GO:0007419	ventral cord development

0.55	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.51	GO:0003676	nucleic acid binding
0.35	GO:0046872	metal ion binding

0.45	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P07486|G3P1_DROME
Glyceraldehyde-3-phosphate dehydrogenase 1
Search

0.51	Glyceraldehyde-3-phosphate dehydrogenase

0.67	GO:0006006	glucose metabolic process
0.66	GO:0006757	ATP generation from ADP
0.64	GO:0006090	pyruvate metabolic process
0.63	GO:0016052	carbohydrate catabolic process
0.63	GO:0019362	pyridine nucleotide metabolic process
0.53	GO:0055114	oxidation-reduction process
0.43	GO:0042593	glucose homeostasis
0.40	GO:0007525	somatic muscle development
0.40	GO:0007520	myoblast fusion
0.34	GO:0006000	fructose metabolic process

0.77	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
0.65	GO:0050661	NADP binding
0.64	GO:0051287	NAD binding
0.34	GO:0003873	6-phosphofructo-2-kinase activity
0.33	GO:0008886	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032553	ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0031430	M band
0.40	GO:0030018	Z disc
0.35	GO:0015630	microtubule cytoskeleton

0.77	EC:1.2.1.12	GO:0004365
0.34	KEGG:R02732	GO:0003873

sp|P07487|G3P2_DROME
Glyceraldehyde-3-phosphate dehydrogenase 2
Search

0.50	Glyceraldehyde-3-phosphate dehydrogenase

0.67	GO:0006006	glucose metabolic process
0.66	GO:0006757	ATP generation from ADP
0.65	GO:0006090	pyruvate metabolic process
0.64	GO:0016052	carbohydrate catabolic process
0.64	GO:0019362	pyridine nucleotide metabolic process
0.53	GO:0055114	oxidation-reduction process
0.43	GO:0042593	glucose homeostasis
0.40	GO:0007525	somatic muscle development
0.40	GO:0007520	myoblast fusion
0.34	GO:0006000	fructose metabolic process

0.78	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
0.66	GO:0050661	NADP binding
0.64	GO:0051287	NAD binding
0.34	GO:0003873	6-phosphofructo-2-kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032553	ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0031430	M band
0.39	GO:0030018	Z disc
0.35	GO:0015630	microtubule cytoskeleton

0.78	EC:1.2.1.12	GO:0004365
0.34	KEGG:R02732	GO:0003873

sp|P07548|DFD_DROME
Homeotic protein deformed
Search

0.79	Homeotic protein deformed

0.64	GO:0007275	multicellular organism development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:1902339	positive regulation of apoptotic process involved in morphogenesis
0.52	GO:0060323	head morphogenesis
0.47	GO:0051254	positive regulation of RNA metabolic process
0.47	GO:0010557	positive regulation of macromolecule biosynthetic process
0.47	GO:0031328	positive regulation of cellular biosynthetic process
0.46	GO:0051253	negative regulation of RNA metabolic process

0.64	GO:0043565	sequence-specific DNA binding
0.58	GO:0003700	DNA binding transcription factor activity
0.52	GO:0033613	activating transcription factor binding
0.52	GO:0035326	enhancer binding
0.49	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003690	double-stranded DNA binding
0.33	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33

GO:0004000

sp|P07663|PER_DROME
Period circadian protein
Search

PER

0.65	period circadian protein isoform X1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0048511	rhythmic process
0.47	GO:0045187	regulation of circadian sleep/wake cycle, sleep
0.45	GO:0007562	eclosion
0.45	GO:0010243	response to organonitrogen compound
0.45	GO:0048609	multicellular organismal reproductive process
0.45	GO:1904059	regulation of locomotor rhythm
0.45	GO:0019953	sexual reproduction

0.46	GO:0046982	protein heterodimerization activity
0.42	GO:0003714	transcription corepressor activity
0.42	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.42	GO:0017022	myosin binding
0.41	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.41	GO:0042803	protein homodimerization activity
0.40	GO:0008134	transcription factor binding
0.39	GO:0043565	sequence-specific DNA binding
0.38	GO:0001012	RNA polymerase II regulatory region DNA binding
0.37	GO:0003690	double-stranded DNA binding

0.47	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0005634	nucleus
0.39	GO:0005829	cytosol
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.37	GO:0043234	protein complex

sp|P07664|SRYD_DROME
Serendipity locus protein delta
Search

SRY-DELTA

0.47

Sry-delta

0.70	GO:0045450	bicoid mRNA localization
0.60	GO:0006366	transcription by RNA polymerase II
0.60	GO:0045944	positive regulation of transcription by RNA polymerase II
0.33	GO:0000724	double-strand break repair via homologous recombination
0.32	GO:0042254	ribosome biogenesis
0.32	GO:0006352	DNA-templated transcription, initiation
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0036211	protein modification process
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0016310	phosphorylation

0.64	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0003676	nucleic acid binding
0.38	GO:0046872	metal ion binding
0.32	GO:0017056	structural constituent of nuclear pore
0.32	GO:0046982	protein heterodimerization activity
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0030554	adenyl nucleotide binding

0.73	GO:0005705	polytene chromosome interband
0.53	GO:0005634	nucleus
0.32	GO:0012505	endomembrane system
0.32	GO:0032991	macromolecular complex
0.32	GO:0031967	organelle envelope
0.31	GO:0044444	cytoplasmic part

sp|P07665|SRYB_DROME
Serendipity locus protein beta
Search

SRY-BETA

0.50	Serendipity beta

0.51	GO:0045450	bicoid mRNA localization
0.46	GO:0006366	transcription by RNA polymerase II
0.46	GO:0045944	positive regulation of transcription by RNA polymerase II

0.51	GO:0003676	nucleic acid binding
0.48	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0046872	metal ion binding

0.67	GO:0005705	polytene chromosome interband
0.50	GO:0005634	nucleus

sp|P07666|SRYA_DROME
Serendipity locus protein alpha
Search

SRY-ALPHA

0.96	Serendipity alpha

0.85	GO:0007349	cellularization
0.65	GO:0007015	actin filament organization
0.42	GO:0044837	actomyosin contractile ring organization
0.42	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis

0.39

GO:0003779

actin binding

0.75	GO:0031941	filamentous actin
0.75	GO:0032154	cleavage furrow
0.60	GO:0005829	cytosol
0.51	GO:0005886	plasma membrane

sp|P07668|CLAT_DROME
Choline O-acetyltransferase
Search

0.85	Choline O-acetyltransferase

0.54	GO:0008292	acetylcholine biosynthetic process
0.52	GO:0007274	neuromuscular synaptic transmission
0.36	GO:0007399	nervous system development
0.35	GO:0006855	drug transmembrane transport

0.63	GO:0016746	transferase activity, transferring acyl groups
0.35	GO:0015238	drug transmembrane transporter activity

0.35	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.63

EC:2.3

GO:0016746

sp|P07701|SGS5_DROME
Salivary glue protein Sgs-5
Search

0.93	Salivary glue protein Sgs-5

sp|P07713|DECA_DROME
Protein decapentaplegic
Search

DPP

0.76	Decapentaplegic transforming growth factor beta

0.76	GO:0010469	regulation of receptor activity
0.60	GO:0035156	fusion cell fate specification
0.60	GO:0030721	spectrosome organization
0.60	GO:0061352	cell chemotaxis involved in Malpighian tubule morphogenesis
0.59	GO:0035217	labial disc development
0.59	GO:0035168	larval lymph gland hemocyte differentiation
0.59	GO:0007516	hemocyte development
0.59	GO:0035224	genital disc anterior/posterior pattern formation
0.59	GO:0035263	genital disc sexually dimorphic development
0.59	GO:0007458	progression of morphogenetic furrow involved in compound eye morphogenesis

0.78	GO:0008083	growth factor activity
0.54	GO:0005518	collagen binding
0.54	GO:0008201	heparin binding
0.50	GO:0042803	protein homodimerization activity
0.50	GO:0046982	protein heterodimerization activity
0.39	GO:0005160	transforming growth factor beta receptor binding
0.39	GO:0005125	cytokine activity
0.38	GO:0016015	morphogen activity
0.34	GO:0070700	BMP receptor binding

0.66	GO:0005576	extracellular region
0.59	GO:0035230	cytoneme
0.51	GO:0005768	endosome
0.30	GO:0016020	membrane

sp|P07764|ALF_DROME
Fructose-bisphosphate aldolase
Search

0.56	Fructose-bisphosphate aldolase

0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.35	GO:0007498	mesoderm development
0.35	GO:0042593	glucose homeostasis

0.79

GO:0004332

fructose-bisphosphate aldolase activity

0.35	GO:0031430	M band
0.35	GO:0030018	Z disc
0.34	GO:0005829	cytosol

0.79

EC:4.1.2.13

GO:0004332

sp|P07909|ROA1_DROME
Heterogeneous nuclear ribonucleoprotein A1
Search

0.76	Putative rna-binding protein musashi/mrna cleavage and polyadenylation factor i complex

0.54	GO:0001745	compound eye morphogenesis
0.54	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.51	GO:0036099	female germ-line stem cell population maintenance
0.50	GO:0033119	negative regulation of RNA splicing
0.50	GO:0003006	developmental process involved in reproduction
0.48	GO:0007292	female gamete generation
0.47	GO:0022412	cellular process involved in reproduction in multicellular organism
0.47	GO:0045727	positive regulation of translation
0.46	GO:0048468	cell development
0.43	GO:0061458	reproductive system development

0.59	GO:0003723	RNA binding
0.45	GO:0043565	sequence-specific DNA binding
0.34	GO:0003777	microtubule motor activity
0.34	GO:0008017	microtubule binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0051082	unfolded protein binding

0.55	GO:0005703	polytene chromosome puff
0.55	GO:0019013	viral nucleocapsid
0.53	GO:0030529	intracellular ribonucleoprotein complex
0.47	GO:0035062	omega speckle
0.44	GO:0000792	heterochromatin
0.32	GO:0030286	dynein complex
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P08044|SNAI_DROME
Protein snail
Search

SNAI2

0.79	Snail family transcriptional repressor 2

0.57	GO:0045216	cell-cell junction organization
0.56	GO:0007370	ventral furrow formation
0.56	GO:0055059	asymmetric neuroblast division
0.56	GO:0031065	positive regulation of histone deacetylation
0.55	GO:0007443	Malpighian tubule morphogenesis
0.55	GO:0000122	negative regulation of transcription by RNA polymerase II
0.53	GO:0048749	compound eye development
0.51	GO:0007417	central nervous system development
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.48	GO:0070563	negative regulation of vitamin D receptor signaling pathway

0.54	GO:0001106	RNA polymerase II transcription corepressor activity
0.54	GO:0070491	repressing transcription factor binding
0.51	GO:0003676	nucleic acid binding
0.46	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.41	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.39	GO:0003682	chromatin binding
0.35	GO:0046872	metal ion binding

0.46	GO:0005634	nucleus
0.42	GO:0000785	chromatin
0.41	GO:0070013	intracellular organelle lumen
0.34	GO:0005737	cytoplasm

sp|P08099|OPS2_DROME
Opsin Rh2
Search

0.47	Long wavelength-sensitive visual pigment

0.79	GO:0007602	phototransduction
0.76	GO:0007601	visual perception
0.73	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.53	GO:0009584	detection of visible light
0.51	GO:0043052	thermotaxis
0.49	GO:0046673	negative regulation of compound eye retinal cell programmed cell death
0.49	GO:0009589	detection of UV
0.49	GO:0071632	optomotor response
0.48	GO:0042331	phototaxis

0.78	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005515	protein binding

0.51	GO:0016028	rhabdomere
0.49	GO:0120082	smooth endoplasmic reticulum cisterna
0.47	GO:0005767	secondary lysosome
0.47	GO:0097038	perinuclear endoplasmic reticulum
0.47	GO:0005771	multivesicular body
0.46	GO:0005791	rough endoplasmic reticulum
0.45	GO:0005769	early endosome
0.44	GO:0019897	extrinsic component of plasma membrane
0.44	GO:0120038	plasma membrane bounded cell projection part
0.41	GO:0098797	plasma membrane protein complex

sp|P08111|L2GL_DROME
Lethal(2) giant larvae protein
Search

0.91	Lethal giant larva

0.87	GO:0090163	establishment of epithelial cell planar polarity
0.86	GO:0045175	basal protein localization
0.86	GO:0098725	symmetric cell division
0.86	GO:0035072	ecdysone-mediated induction of salivary gland cell autophagic cell death
0.85	GO:0035293	chitin-based larval cuticle pattern formation
0.85	GO:0045196	establishment or maintenance of neuroblast polarity
0.85	GO:0045167	asymmetric protein localization involved in cell fate determination
0.85	GO:0035212	cell competition in a multicellular organism
0.85	GO:0016334	establishment or maintenance of polarity of follicular epithelium
0.85	GO:0016325	oocyte microtubule cytoskeleton organization

0.86	GO:0045159	myosin II binding
0.80	GO:0000149	SNARE binding
0.80	GO:0004860	protein kinase inhibitor activity
0.49	GO:0017137	Rab GTPase binding
0.48	GO:0005096	GTPase activator activity

0.86	GO:0005920	smooth septate junction
0.84	GO:0016327	apicolateral plasma membrane
0.77	GO:0030863	cortical cytoskeleton
0.75	GO:0005578	proteinaceous extracellular matrix
0.46	GO:0016323	basolateral plasma membrane
0.46	GO:0008021	synaptic vesicle
0.42	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|P08120|CO4A1_DROME
Collagen alpha-1(IV) chain
Search

LET-2

0.67	C-terminal tandem repeated domain in type 4 procollagen

0.54	GO:0035848	oviduct morphogenesis
0.53	GO:0048621	post-embryonic digestive tract morphogenesis
0.52	GO:0060729	intestinal epithelial structure maintenance
0.50	GO:0055013	cardiac muscle cell development
0.38	GO:0007391	dorsal closure
0.35	GO:1903354	regulation of distal tip cell migration
0.35	GO:0035262	gonad morphogenesis
0.34	GO:0048846	axon extension involved in axon guidance
0.34	GO:0071711	basement membrane organization
0.33	GO:0008104	protein localization

0.82	GO:0005201	extracellular matrix structural constituent
0.35	GO:0005515	protein binding
0.34	GO:0004838	L-tyrosine:2-oxoglutarate aminotransferase activity
0.33	GO:0005459	UDP-galactose transmembrane transporter activity
0.33	GO:0070279	vitamin B6 binding
0.32	GO:0005351	sugar:proton symporter activity
0.32	GO:0050662	coenzyme binding
0.32	GO:0016787	hydrolase activity
0.32	GO:0043168	anion binding

0.82	GO:0005604	basement membrane
0.79	GO:0005581	collagen trimer
0.40	GO:0098645	collagen network
0.33	GO:0005634	nucleus
0.33	GO:0005797	Golgi medial cisterna
0.32	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.6.1.5

GO:0004838

sp|P08144|AMYA_DROME
Alpha-amylase A
Search

0.43	Alpha-amylase A

0.60

GO:0005975

carbohydrate metabolic process

0.71	GO:0103025	alpha-amylase activity (releasing maltohexaose)
0.70	GO:0004556	alpha-amylase activity
0.53	GO:0043169	cation binding

0.33

GO:0005576

extracellular region

0.70

GO:0004556

sp|P08155|KRH1_DROME
Krueppel homolog 1
Search

0.34	Krueppel ous protein 1

0.58	GO:0042480	negative regulation of eye photoreceptor cell development
0.57	GO:0045314	regulation of compound eye photoreceptor development
0.55	GO:0035075	response to ecdysone
0.54	GO:0010977	negative regulation of neuron projection development
0.53	GO:0007552	metamorphosis
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:0010468	regulation of gene expression

0.51	GO:0003676	nucleic acid binding
0.35	GO:0046872	metal ion binding
0.35	GO:0003700	DNA binding transcription factor activity

0.35

GO:0005634

nucleus

sp|P08171|EST6_DROME
Esterase-6
Search

0.43	Carboxylic ester hydrolase

0.58	GO:0042811	pheromone biosynthetic process
0.56	GO:0007619	courtship behavior
0.44	GO:1901575	organic substance catabolic process
0.38	GO:0046693	sperm storage
0.38	GO:0046008	regulation of female receptivity, post-mating
0.37	GO:0030728	ovulation
0.37	GO:0046662	regulation of oviposition
0.32	GO:0006508	proteolysis

0.58	GO:0052689	carboxylic ester hydrolase activity
0.32	GO:0046872	metal ion binding
0.32	GO:0004222	metalloendopeptidase activity

0.51	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.58	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.58	KEGG:R00630	GO:0052689

sp|P08175|MS87F_DROME
Male-specific sperm protein Mst87F
Search

0.97	Testis-specific RNA

0.67	GO:0007283	spermatogenesis
0.58	GO:0007281	germ cell development
0.57	GO:0030317	flagellated sperm motility
0.57	GO:0035082	axoneme assembly
0.49	GO:0007275	multicellular organism development
0.47	GO:0001558	regulation of cell growth

0.48	GO:0005520	insulin-like growth factor binding
0.40	GO:0019904	protein domain specific binding
0.39	GO:0005198	structural molecule activity

0.67	GO:0036126	sperm flagellum
0.51	GO:0044441	ciliary part
0.49	GO:0099513	polymeric cytoskeletal fiber
0.42	GO:0005576	extracellular region
0.39	GO:0005581	collagen trimer
0.36	GO:0045111	intermediate filament cytoskeleton
0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P08181|CSK2A_DROME
Casein kinase II subunit alpha
Search

0.51	Casein kinase II subunit alpha

0.63	GO:0006468	protein phosphorylation
0.48	GO:0046331	lateral inhibition
0.48	GO:0007228	positive regulation of hh target transcription factor activity
0.47	GO:0007310	oocyte dorsal/ventral axis specification
0.47	GO:0060810	intracellular mRNA localization involved in pattern specification process
0.47	GO:0022416	chaeta development
0.47	GO:0045475	locomotor rhythm
0.47	GO:0045880	positive regulation of smoothened signaling pathway
0.46	GO:0031397	negative regulation of protein ubiquitination
0.46	GO:0048749	compound eye development

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.45	GO:0005956	protein kinase CK2 complex
0.41	GO:0005829	cytosol
0.39	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.70

GO:0004674

sp|P08182|CSK2B_DROME
Casein kinase II subunit beta
Search

0.55	Casein kinase II subunit beta

0.76	GO:0045859	regulation of protein kinase activity
0.48	GO:0016310	phosphorylation
0.42	GO:0007310	oocyte dorsal/ventral axis specification
0.42	GO:0060810	intracellular mRNA localization involved in pattern specification process
0.42	GO:0016319	mushroom body development
0.42	GO:0045475	locomotor rhythm
0.39	GO:0033211	adiponectin-activated signaling pathway
0.39	GO:0032927	positive regulation of activin receptor signaling pathway
0.39	GO:0061154	endothelial tube morphogenesis
0.39	GO:0043537	negative regulation of blood vessel endothelial cell migration

0.79	GO:0019887	protein kinase regulator activity
0.50	GO:0016301	kinase activity
0.38	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.37	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0003682	chromatin binding
0.37	GO:0019904	protein domain specific binding
0.37	GO:0042802	identical protein binding
0.36	GO:0008134	transcription factor binding
0.36	GO:0005102	receptor binding
0.34	GO:0046872	metal ion binding

0.83	GO:0005956	protein kinase CK2 complex
0.40	GO:0031519	PcG protein complex
0.38	GO:0005829	cytosol
0.34	GO:0005886	plasma membrane

0.38

GO:0016773

sp|P08255|OPS4_DROME
Opsin Rh4
Search

0.82	Short wavelength-sensitive opsin

0.79	GO:0007602	phototransduction
0.78	GO:0007601	visual perception
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.70	GO:0018298	protein-chromophore linkage
0.57	GO:0009589	detection of UV
0.53	GO:0034644	cellular response to UV
0.52	GO:0009584	detection of visible light
0.47	GO:0016039	absorption of UV light

0.74	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.30

GO:0044425

membrane part

sp|P08266|RPB2_DROME
DNA-directed RNA polymerase II subunit RPB2
Search

RPB2

0.41	DNA-directed RNA polymerase subunit beta

0.58	GO:0006351	transcription, DNA-templated
0.34	GO:0006801	superoxide metabolic process

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.65	GO:0001882	nucleoside binding
0.55	GO:0003677	DNA binding
0.33	GO:0046872	metal ion binding

0.41	GO:0005665	DNA-directed RNA polymerase II, core complex
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0003899

sp|P08510|KCNAS_DROME
Potassium voltage-gated channel protein Shaker
Search

0.84	Potassium voltage-gated channel protein Shaker

0.77	GO:0051260	protein homooligomerization
0.77	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071804	cellular potassium ion transport
0.62	GO:0098662	inorganic cation transmembrane transport
0.44	GO:0007637	proboscis extension reflex
0.43	GO:0048047	mating behavior, sex discrimination
0.43	GO:0060025	regulation of synaptic activity
0.43	GO:1903351	cellular response to dopamine
0.43	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep
0.43	GO:0045838	positive regulation of membrane potential

0.78	GO:0005249	voltage-gated potassium channel activity
0.33	GO:0005515	protein binding

0.78

GO:0008076

voltage-gated potassium channel complex

sp|P08570|RLA1_DROME
60S acidic ribosomal protein P1
Search

0.74	Ribosomal protein 7

0.69	GO:0006414	translational elongation
0.36	GO:0032147	activation of protein kinase activity
0.36	GO:0002181	cytoplasmic translation
0.35	GO:0009264	deoxyribonucleotide catabolic process
0.33	GO:0016567	protein ubiquitination
0.33	GO:0006281	DNA repair

0.63	GO:0003735	structural constituent of ribosome
0.37	GO:0030295	protein kinase activator activity
0.35	GO:0004139	deoxyribose-phosphate aldolase activity
0.33	GO:0005515	protein binding
0.33	GO:0004842	ubiquitin-protein transferase activity

0.61	GO:0005840	ribosome
0.36	GO:0044445	cytosolic part
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.35	EC:4.1.2.4	GO:0004139
0.35	KEGG:R01066	GO:0004139

sp|P08630|BTKL_DROME
Tyrosine-protein kinase Btk29A
Search

0.55	Tyrosine-protein kinase

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.53	GO:0046960	sensitization
0.53	GO:0007301	female germline ring canal formation
0.53	GO:0030723	ovarian fusome organization
0.52	GO:0007485	imaginal disc-derived male genitalia development
0.52	GO:0035277	spiracle morphogenesis, open tracheal system
0.52	GO:0044719	regulation of imaginal disc-derived wing size
0.52	GO:0030717	karyosome formation
0.52	GO:0035556	intracellular signal transduction
0.52	GO:0008258	head involution

0.80	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0005102	receptor binding
0.33	GO:0046872	metal ion binding
0.33	GO:0048038	quinone binding
0.33	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.33	GO:0051539	4 iron, 4 sulfur cluster binding

0.52	GO:0045172	germline ring canal
0.48	GO:0045177	apical part of cell
0.40	GO:0005622	intracellular
0.40	GO:0005886	plasma membrane
0.38	GO:0098562	cytoplasmic side of membrane
0.38	GO:0019898	extrinsic component of membrane

0.80

GO:0004715

sp|P08645|RAS3_DROME
Ras-like protein 3
Search

0.56	ADP ribosylation factor

0.61	GO:0007165	signal transduction
0.48	GO:0006930	substrate-dependent cell migration, cell extension
0.48	GO:0035099	hemocyte migration
0.48	GO:0016476	regulation of embryonic cell shape
0.47	GO:0042067	establishment of ommatidial planar polarity
0.47	GO:0007391	dorsal closure
0.47	GO:0030718	germ-line stem cell population maintenance
0.46	GO:0034333	adherens junction assembly
0.44	GO:0022409	positive regulation of cell-cell adhesion
0.38	GO:0040002	collagen and cuticulin-based cuticle development

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004767	sphingomyelin phosphodiesterase activity
0.33	GO:0005515	protein binding
0.33	GO:0016746	transferase activity, transferring acyl groups

0.45	GO:0031252	cell leading edge
0.35	GO:0005622	intracellular
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.35	EC:3.1.4.12	GO:0004767
0.35	KEGG:R02541	GO:0004767

sp|P08646|RAS1_DROME
Ras-like protein 1
Search

0.48	ADP ribosylation factor

0.61	GO:0007165	signal transduction
0.49	GO:0035208	positive regulation of hemocyte proliferation
0.48	GO:0002164	larval development
0.48	GO:0046673	negative regulation of compound eye retinal cell programmed cell death
0.48	GO:0007395	dorsal closure, spreading of leading edge cells
0.48	GO:0030381	chorion-containing eggshell pattern formation
0.48	GO:0046534	positive regulation of photoreceptor cell differentiation
0.48	GO:0048569	post-embryonic animal organ development
0.47	GO:0035099	hemocyte migration
0.47	GO:0007426	tracheal outgrowth, open tracheal system

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.41	GO:0043274	phospholipase binding
0.41	GO:0017034	Rap guanyl-nucleotide exchange factor activity
0.39	GO:0019901	protein kinase binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.32	GO:0003676	nucleic acid binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding

0.39	GO:0071944	cell periphery
0.38	GO:0099568	cytoplasmic region
0.33	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

sp|P08736|EF1A1_DROME
Elongation factor 1-alpha 1
Search

0.43	Elongation factor 1-alpha

0.70	GO:0006414	translational elongation
0.41	GO:0008340	determination of adult lifespan

0.71	GO:0003746	translation elongation factor activity
0.67	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding

0.43	GO:0005737	cytoplasm
0.34	GO:0043234	protein complex

sp|P08761|MSRA_DROME
Peptide methionine sulfoxide reductase
Search

0.55	Methionine sulfoxide reductase-ecdysone inducible

0.53	GO:0055114	oxidation-reduction process
0.40	GO:0006464	cellular protein modification process
0.36	GO:0008340	determination of adult lifespan
0.35	GO:0034599	cellular response to oxidative stress
0.34	GO:0000096	sulfur amino acid metabolic process

0.78

GO:0008113

peptide-methionine (S)-S-oxide reductase activity

0.30

GO:0031224

intrinsic component of membrane

0.78

EC:1.8.4 EC:1.8.4.11

GO:0008113

sp|P08841|TBB3_DROME
Tubulin beta-3 chain
Search

0.50	Tubulin beta chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.45	GO:0030537	larval behavior
0.43	GO:0007411	axon guidance
0.42	GO:0009416	response to light stimulus
0.34	GO:0007507	heart development

0.77	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0005874	microtubule
0.44	GO:0005737	cytoplasm
0.34	GO:0044441	ciliary part

sp|P08879|NDKA_DROME
Nucleoside diphosphate kinase
Search

0.46	Nucleoside diphosphate kinase

0.79	GO:0006228	UTP biosynthetic process
0.79	GO:0006183	GTP biosynthetic process
0.75	GO:0046036	CTP metabolic process
0.70	GO:0006165	nucleoside diphosphate phosphorylation
0.47	GO:0007427	epithelial cell migration, open tracheal system
0.47	GO:0016334	establishment or maintenance of polarity of follicular epithelium
0.46	GO:0035152	regulation of tube architecture, open tracheal system
0.46	GO:0034332	adherens junction organization
0.45	GO:0046777	protein autophosphorylation
0.45	GO:0018105	peptidyl-serine phosphorylation

0.79	GO:0004550	nucleoside diphosphate kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0008017	microtubule binding
0.41	GO:0019001	guanyl nucleotide binding
0.40	GO:0000287	magnesium ion binding
0.36	GO:0043024	ribosomal small subunit binding
0.34	GO:0019215	intermediate filament binding

0.47	GO:0005880	nuclear microtubule
0.38	GO:0001726	ruffle
0.38	GO:0043209	myelin sheath
0.37	GO:0030027	lamellipodium
0.35	GO:0005925	focal adhesion
0.35	GO:0005829	cytosol
0.35	GO:0031256	leading edge membrane
0.35	GO:0070062	extracellular exosome
0.35	GO:0031253	cell projection membrane
0.35	GO:0005739	mitochondrion

0.79

EC:2.7.4.6

GO:0004550

sp|P08928|LAM0_DROME
Lamin Dm0
Search

0.85	Nuclear envelope protein lamin

0.52	GO:0070870	heterochromatin maintenance involved in chromatin silencing
0.52	GO:1905832	positive regulation of spindle assembly
0.51	GO:0007110	meiosis I cytokinesis
0.51	GO:0007430	terminal branching, open tracheal system
0.51	GO:0048137	spermatocyte division
0.51	GO:2000433	positive regulation of cytokinesis, actomyosin contractile ring assembly
0.51	GO:0071763	nuclear membrane organization
0.51	GO:0007112	male meiosis cytokinesis
0.51	GO:0035262	gonad morphogenesis
0.51	GO:0031081	nuclear pore distribution

0.62	GO:0005198	structural molecule activity
0.45	GO:0005102	receptor binding

0.79	GO:0005882	intermediate filament
0.53	GO:0070732	spindle envelope
0.51	GO:0005652	nuclear lamina
0.46	GO:0005635	nuclear envelope
0.37	GO:0036338	viral membrane
0.36	GO:0000922	spindle pole
0.34	GO:0019866	organelle inner membrane
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P08953|TOLL_DROME
Protein toll
Search

0.92	Toll-like-2. Transmembrane receptor with TIR domain binding (Fragment)

0.75	GO:0045087	innate immune response
0.60	GO:0007165	signal transduction
0.44	GO:0002807	positive regulation of antimicrobial peptide biosynthetic process
0.41	GO:0002810	regulation of antifungal peptide biosynthetic process
0.40	GO:0002804	positive regulation of antifungal peptide production
0.39	GO:0035172	hemocyte proliferation
0.39	GO:0035007	regulation of melanization defense response
0.39	GO:0007352	zygotic specification of dorsal/ventral axis
0.39	GO:0016201	synaptic target inhibition
0.39	GO:0002229	defense response to oomycetes

0.43	GO:0005121	Toll binding
0.41	GO:0015026	coreceptor activity
0.39	GO:0019901	protein kinase binding
0.39	GO:0070976	TIR domain binding
0.38	GO:0019955	cytokine binding
0.36	GO:0042802	identical protein binding
0.36	GO:0004888	transmembrane signaling receptor activity
0.34	GO:0004721	phosphoprotein phosphatase activity

0.38	GO:0097610	cell surface furrow
0.37	GO:0009897	external side of plasma membrane
0.37	GO:0032155	cell division site part
0.37	GO:0005769	early endosome
0.34	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.34

GO:0004721

sp|P08970|SUHW_DROME
Protein suppressor of hairy wing
Search

SU(HW)

0.91	LOW QUALITY PROTEIN: protein suppressor of hairy wing

0.57	GO:0035075	response to ecdysone
0.56	GO:0031936	negative regulation of chromatin silencing
0.49	GO:0045892	negative regulation of transcription, DNA-templated
0.43	GO:0006351	transcription, DNA-templated
0.37	GO:0016569	covalent chromatin modification
0.33	GO:0040034	regulation of development, heterochronic
0.32	GO:0015074	DNA integration
0.32	GO:0006310	DNA recombination
0.32	GO:0006357	regulation of transcription by RNA polymerase II
0.32	GO:0043044	ATP-dependent chromatin remodeling

0.59	GO:0043035	chromatin insulator sequence binding
0.47	GO:0043565	sequence-specific DNA binding
0.38	GO:0046872	metal ion binding
0.36	GO:0044212	transcription regulatory region DNA binding
0.36	GO:0003690	double-stranded DNA binding
0.35	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0008168	methyltransferase activity

0.55	GO:0005700	polytene chromosome
0.50	GO:0000785	chromatin
0.45	GO:0005634	nucleus
0.32	GO:0005789	endoplasmic reticulum membrane
0.32	GO:0043233	organelle lumen
0.31	GO:1904949	ATPase complex
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0008168

sp|P08985|H2AV_DROME
Histone H2A.v
Search

0.47	GO:0036098	male germ-line stem cell population maintenance
0.45	GO:0071168	protein localization to chromatin
0.45	GO:0006342	chromatin silencing
0.45	GO:0035019	somatic stem cell population maintenance
0.37	GO:0071392	cellular response to estradiol stimulus
0.36	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0007275	multicellular organism development
0.33	GO:0006281	DNA repair
0.33	GO:0007165	signal transduction

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.37	GO:0031491	nucleosome binding
0.36	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0050840	extracellular matrix binding
0.34	GO:0005518	collagen binding
0.33	GO:0003774	motor activity
0.33	GO:0005509	calcium ion binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.46	GO:0005701	polytene chromosome chromocenter
0.45	GO:0031974	membrane-enclosed lumen
0.44	GO:0035861	site of double-strand break
0.42	GO:0031248	protein acetyltransferase complex
0.38	GO:0043234	protein complex
0.37	GO:0000791	euchromatin
0.37	GO:0000792	heterochromatin
0.35	GO:0005615	extracellular space

sp|P09040|DSK_DROME
Drosulfakinins
Search

DSK

0.97	Callisulfakinin

0.67	GO:0007218	neuropeptide signaling pathway
0.61	GO:0008345	larval locomotory behavior
0.61	GO:0008343	adult feeding behavior
0.59	GO:0033555	multicellular organismal response to stress
0.59	GO:0006939	smooth muscle contraction
0.59	GO:0006940	regulation of smooth muscle contraction
0.59	GO:0007528	neuromuscular junction development
0.58	GO:0008344	adult locomotory behavior
0.58	GO:0010469	regulation of receptor activity
0.57	GO:0007204	positive regulation of cytosolic calcium ion concentration

0.61	GO:0071855	neuropeptide receptor binding
0.60	GO:0005179	hormone activity
0.35	GO:0019781	NEDD8 activating enzyme activity
0.34	GO:0016881	acid-amino acid ligase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane
0.30	GO:0005623	cell

0.34

EC:6.3.2

GO:0016881

sp|P09052|VASA1_DROME
ATP-dependent RNA helicase vasa, isoform A
Search

0.40	ATP-dependent RNA helicase vasa

0.47	GO:0045727	positive regulation of translation
0.47	GO:0007059	chromosome segregation
0.47	GO:0007316	pole plasm RNA localization
0.46	GO:0007293	germarium-derived egg chamber formation
0.44	GO:0010501	RNA secondary structure unwinding
0.44	GO:0000280	nuclear division
0.44	GO:1903608	protein localization to cytoplasmic stress granule
0.44	GO:0051276	chromosome organization
0.43	GO:0071243	cellular response to arsenic-containing substance
0.43	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors

0.66	GO:0004386	helicase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.51	GO:0003676	nucleic acid binding
0.48	GO:0008186	RNA-dependent ATPase activity
0.45	GO:0043273	CTPase activity
0.43	GO:0008190	eukaryotic initiation factor 4E binding
0.43	GO:0043024	ribosomal small subunit binding

0.50	GO:0036464	cytoplasmic ribonucleoprotein granule
0.48	GO:0045170	spectrosome
0.48	GO:0060293	germ plasm
0.44	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0022627	cytosolic small ribosomal subunit
0.41	GO:0005852	eukaryotic translation initiation factor 3 complex
0.40	GO:0005634	nucleus
0.39	GO:0070013	intracellular organelle lumen
0.36	GO:0000775	chromosome, centromeric region
0.35	GO:0000793	condensed chromosome

0.34

EC:2.7.7

GO:0016779

sp|P09077|SCR_DROME
Homeotic protein Sex combs reduced
Search

SCR

0.62	Homeotic protein Sex combs reduced

0.65	GO:0007275	multicellular organism development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0045617	negative regulation of keratinocyte differentiation
0.48	GO:0045656	negative regulation of monocyte differentiation
0.47	GO:0002686	negative regulation of leukocyte migration
0.47	GO:0001953	negative regulation of cell-matrix adhesion
0.45	GO:0048863	stem cell differentiation
0.45	GO:0051254	positive regulation of RNA metabolic process

0.64	GO:0043565	sequence-specific DNA binding
0.58	GO:0003700	DNA binding transcription factor activity
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003690	double-stranded DNA binding
0.43	GO:0008134	transcription factor binding
0.39	GO:0042803	protein homodimerization activity
0.33	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.41	GO:0012505	endomembrane system
0.41	GO:0043233	organelle lumen
0.39	GO:0031967	organelle envelope
0.39	GO:0031090	organelle membrane

0.33

GO:0004000

sp|P09081|BCD_DROME
Homeotic protein bicoid
Search

BCD

0.97	Homeotic protein bicoid

0.64	GO:0007355	anterior region determination
0.61	GO:0007367	segment polarity determination
0.57	GO:0048477	oogenesis
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.54	GO:0034249	negative regulation of cellular amide metabolic process
0.53	GO:1902680	positive regulation of RNA biosynthetic process
0.52	GO:0032269	negative regulation of cellular protein metabolic process
0.51	GO:0010558	negative regulation of macromolecule biosynthetic process

0.62	GO:0043565	sequence-specific DNA binding
0.60	GO:0030371	translation repressor activity
0.59	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.58	GO:0003730	mRNA 3'-UTR binding
0.41	GO:0016015	morphogen activity
0.36	GO:0004402	histone acetyltransferase activity
0.36	GO:0003713	transcription coactivator activity
0.34	GO:0019104	DNA N-glycosylase activity
0.34	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0008430	selenium binding

0.60	GO:0005634	nucleus
0.35	GO:0031248	protein acetyltransferase complex
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0044815	DNA packaging complex
0.33	GO:0032993	protein-DNA complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0031410	cytoplasmic vesicle
0.32	GO:0005667	transcription factor complex
0.32	GO:0005829	cytosol

0.36

GO:0004402

sp|P09082|GSB_DROME
Protein gooseberry
Search

0.90	Segmentation protein paired

0.70	GO:0007275	multicellular organism development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0060025	regulation of synaptic activity
0.47	GO:0030154	cell differentiation
0.46	GO:0007268	chemical synaptic transmission
0.44	GO:0009653	anatomical structure morphogenesis
0.35	GO:1902680	positive regulation of RNA biosynthetic process

0.63	GO:0043565	sequence-specific DNA binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.37	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.33	GO:0008061	chitin binding

0.61	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|P09083|GSBN_DROME
Protein gooseberry-neuro
Search

0.83	Gooseberry-neuro

0.70	GO:0007275	multicellular organism development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0030154	cell differentiation
0.45	GO:0060025	regulation of synaptic activity
0.42	GO:0007268	chemical synaptic transmission
0.40	GO:0009653	anatomical structure morphogenesis
0.34	GO:0006030	chitin metabolic process

0.63	GO:0043565	sequence-specific DNA binding
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003690	double-stranded DNA binding
0.34	GO:0008061	chitin binding
0.34	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.33	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.33	GO:0005576	extracellular region

0.33

GO:0004000

sp|P09085|CAD_DROME
Homeotic protein caudal
Search

CAD

0.96	Homeotic protein caudal

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.55	GO:0007275	multicellular organism development
0.46	GO:0009653	anatomical structure morphogenesis
0.45	GO:1902680	positive regulation of RNA biosynthetic process
0.44	GO:0014807	regulation of somitogenesis
0.44	GO:0006366	transcription by RNA polymerase II
0.42	GO:0060429	epithelium development
0.42	GO:0030154	cell differentiation

0.65	GO:0043565	sequence-specific DNA binding
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.45	GO:0003690	double-stranded DNA binding
0.43	GO:0035326	enhancer binding
0.43	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.40	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.39	GO:0003682	chromatin binding
0.32	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm

sp|P09087|ABDB_DROME
Homeobox protein abdominal-B
Search

0.84	Homeobox protein abdominal-B

0.62	GO:0048094	male pigmentation
0.61	GO:0007385	specification of segmental identity, abdomen
0.61	GO:0035261	external genitalia morphogenesis
0.60	GO:0007486	imaginal disc-derived female genitalia development
0.60	GO:0035224	genital disc anterior/posterior pattern formation
0.60	GO:0035263	genital disc sexually dimorphic development
0.60	GO:0009997	negative regulation of cardioblast cell fate specification
0.60	GO:1902339	positive regulation of apoptotic process involved in morphogenesis
0.60	GO:0035225	determination of genital disc primordium
0.60	GO:0046693	sperm storage

0.63	GO:0043565	sequence-specific DNA binding
0.56	GO:0035326	enhancer binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.45	GO:0003700	DNA binding transcription factor activity
0.34	GO:0004000	adenosine deaminase activity

0.61

GO:0005634

nucleus

0.34

GO:0004000

sp|P09089|ZEN1_DROME
Protein zerknuellt 1
Search

ZEN

0.86

Zerknullt

0.60	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:1902680	positive regulation of RNA biosynthetic process
0.49	GO:0010605	negative regulation of macromolecule metabolic process
0.42	GO:0048337	positive regulation of mesodermal cell fate specification
0.40	GO:0009653	anatomical structure morphogenesis
0.38	GO:0050679	positive regulation of epithelial cell proliferation
0.38	GO:0040026	positive regulation of vulval development

0.65	GO:0043565	sequence-specific DNA binding
0.58	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.39	GO:0044212	transcription regulatory region DNA binding
0.38	GO:0003690	double-stranded DNA binding
0.34	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.33	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.36	GO:0005667	transcription factor complex
0.35	GO:0044446	intracellular organelle part
0.33	GO:0005829	cytosol
0.33	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004000

sp|P09090|ZEN2_DROME
Protein zerknuellt 2
Search

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0007275	multicellular organism development
0.49	GO:0050905	neuromuscular process
0.49	GO:0008344	adult locomotory behavior
0.48	GO:0001708	cell fate specification
0.48	GO:0007338	single fertilization
0.48	GO:0014706	striated muscle tissue development
0.47	GO:0061061	muscle structure development

0.65	GO:0043565	sequence-specific DNA binding
0.47	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003682	chromatin binding
0.44	GO:0003690	double-stranded DNA binding
0.32	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.47	GO:0036464	cytoplasmic ribonucleoprotein granule
0.43	GO:0005829	cytosol
0.43	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P09180|RL4_DROME
60S ribosomal protein L4
Search

RPL4

0.60	Ribosomal protein L4

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0003360	brainstem development
0.34	GO:0045773	positive regulation of axon extension
0.34	GO:0071417	cellular response to organonitrogen compound
0.34	GO:0007420	brain development

0.64	GO:0003735	structural constituent of ribosome
0.36	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.39	GO:0044445	cytosolic part
0.37	GO:0005791	rough endoplasmic reticulum
0.36	GO:0044446	intracellular organelle part
0.35	GO:0005634	nucleus
0.34	GO:0031672	A band
0.34	GO:0005925	focal adhesion
0.34	GO:0070062	extracellular exosome
0.33	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

sp|P09208|INSR_DROME
Insulin-like receptor
Search

INR

0.53	Tyrosine-protein kinase receptor

0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.55	GO:0071469	cellular response to alkaline pH
0.54	GO:0007285	primary spermatocyte growth
0.53	GO:0042321	negative regulation of circadian sleep/wake cycle, sleep
0.53	GO:0007446	imaginal disc growth
0.53	GO:0060250	germ-line stem-cell niche homeostasis
0.53	GO:2000252	negative regulation of feeding behavior
0.52	GO:0048133	male germ-line stem cell asymmetric division
0.52	GO:0048132	female germ-line stem cell asymmetric division

0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.50	GO:0016500	protein-hormone receptor activity
0.46	GO:0042802	identical protein binding
0.40	GO:0043560	insulin receptor substrate binding
0.40	GO:0043548	phosphatidylinositol 3-kinase binding
0.39	GO:0043559	insulin binding

0.53	GO:0005899	insulin receptor complex
0.47	GO:0005911	cell-cell junction

0.80

GO:0004714

sp|P09478|ACH1_DROME
Acetylcholine receptor subunit alpha-like 1
Search

0.80	Nicotinic acetyl choline receptor alpha-subunit

0.78	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.37	GO:0017085	response to insecticide
0.37	GO:0007271	synaptic transmission, cholinergic
0.34	GO:0006812	cation transport

0.81	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity

0.77	GO:0045211	postsynaptic membrane
0.72	GO:0030054	cell junction
0.37	GO:0005892	acetylcholine-gated channel complex

sp|P09491|TPM2_DROME
Tropomyosin-2
Search

0.63	Tropomyosin invertebrate

0.84	GO:0060298	positive regulation of sarcomere organization
0.74	GO:0007507	heart development
0.50	GO:0006936	muscle contraction
0.47	GO:0007015	actin filament organization

0.52	GO:0008307	structural constituent of muscle
0.48	GO:0051015	actin filament binding
0.41	GO:0004813	alanine-tRNA ligase activity

0.53	GO:0005862	muscle thin filament tropomyosin
0.50	GO:0005884	actin filament
0.30	GO:0031224	intrinsic component of membrane

0.41

EC:6.1.1.7

GO:0004813

sp|P09615|WNTG_DROME
Protein wingless
Search

sp|P09774|AST3_DROME
Achaete-scute complex protein T3
Search

L(1)SC

0.96	Lethal of scute

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.61	GO:0061382	Malpighian tubule tip cell differentiation
0.60	GO:0007400	neuroblast fate determination
0.57	GO:0061331	epithelial cell proliferation involved in Malpighian tubule morphogenesis
0.51	GO:0045893	positive regulation of transcription, DNA-templated
0.49	GO:0008407	chaeta morphogenesis
0.46	GO:0007422	peripheral nervous system development
0.44	GO:0035883	enteroendocrine cell differentiation
0.43	GO:0007530	sex determination
0.42	GO:0043066	negative regulation of apoptotic process

0.68	GO:0046983	protein dimerization activity
0.55	GO:0003677	DNA binding
0.53	GO:0001067	regulatory region nucleic acid binding
0.45	GO:0003700	DNA binding transcription factor activity
0.41	GO:0008134	transcription factor binding
0.39	GO:0042802	identical protein binding

0.51	GO:0005667	transcription factor complex
0.38	GO:0005634	nucleus
0.35	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

sp|P09775|AST8_DROME
Achaete-scute complex protein T8
Search

ASE

0.97	Achaete-scute complex protein T8

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.65	GO:0061382	Malpighian tubule tip cell differentiation
0.65	GO:0061331	epithelial cell proliferation involved in Malpighian tubule morphogenesis
0.62	GO:0007400	neuroblast fate determination
0.61	GO:0008407	chaeta morphogenesis
0.55	GO:0045839	negative regulation of mitotic nuclear division
0.53	GO:0045893	positive regulation of transcription, DNA-templated
0.45	GO:0007422	peripheral nervous system development
0.41	GO:0002805	regulation of antimicrobial peptide biosynthetic process
0.41	GO:0050767	regulation of neurogenesis

0.68	GO:0046983	protein dimerization activity
0.56	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.51	GO:0042802	identical protein binding
0.39	GO:0003700	DNA binding transcription factor activity

0.47	GO:0005634	nucleus
0.46	GO:0005667	transcription factor complex
0.36	GO:0044446	intracellular organelle part

sp|P09956|ZEST_DROME
Regulatory protein zeste
Search

0.97	Regulatory protein zeste

0.62	GO:0046158	ocellus pigment metabolic process
0.61	GO:0031937	positive regulation of chromatin silencing
0.61	GO:0006726	eye pigment biosynthetic process
0.56	GO:0006351	transcription, DNA-templated
0.54	GO:0045893	positive regulation of transcription, DNA-templated
0.53	GO:0044550	secondary metabolite biosynthetic process
0.40	GO:0006357	regulation of transcription by RNA polymerase II
0.40	GO:0031149	sorocarp stalk cell differentiation
0.39	GO:0045595	regulation of cell differentiation
0.39	GO:1905904	positive regulation of mesoderm formation

0.52	GO:0003677	DNA binding
0.50	GO:0005515	protein binding
0.39	GO:0001104	RNA polymerase II transcription cofactor activity
0.38	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.38	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.37	GO:0003714	transcription corepressor activity
0.37	GO:0003713	transcription coactivator activity
0.37	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.37	GO:0003700	DNA binding transcription factor activity
0.37	GO:0005545	1-phosphatidylinositol binding

0.65	GO:0005725	intercalary heterochromatin
0.61	GO:0005705	polytene chromosome interband
0.60	GO:0035102	PRC1 complex
0.37	GO:0000131	incipient cellular bud site
0.37	GO:0005934	cellular bud tip
0.37	GO:0043332	mating projection tip
0.37	GO:0005935	cellular bud neck
0.37	GO:0010494	cytoplasmic stress granule
0.37	GO:0044451	nucleoplasm part
0.36	GO:0005938	cell cortex

0.37	EC:3.2.1.113	GO:0004571
0.37	KEGG:R05982 KEGG:R06722	GO:0004571

sp|P09957|YELL_DROME
Protein yellow
Search

0.88

Yellow-y

0.85	GO:0060179	male mating behavior
0.84	GO:0042438	melanin biosynthetic process
0.58	GO:0048082	regulation of adult chitin-containing cuticle pigmentation
0.58	GO:0048067	cuticle pigmentation
0.56	GO:0007619	courtship behavior
0.36	GO:0006570	tyrosine metabolic process
0.33	GO:0035725	sodium ion transmembrane transport

0.33

GO:0005272

sodium channel activity

0.59	GO:0070451	cell hair
0.47	GO:0005576	extracellular region
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P0C919|MOC2A_DROME
Molybdopterin synthase sulfur carrier subunit
Search

0.49	Molybdopterin synthase sulfur carrier subunit

0.72	GO:0006777	Mo-molybdopterin cofactor biosynthetic process
0.42	GO:0018315	molybdenum incorporation into molybdenum-molybdopterin complex
0.40	GO:0009734	auxin-activated signaling pathway
0.35	GO:0043086	negative regulation of catalytic activity
0.35	GO:0032324	molybdopterin cofactor biosynthetic process

0.83	GO:0030366	molybdopterin synthase activity
0.50	GO:1901265	nucleoside phosphate binding
0.48	GO:0036094	small molecule binding
0.36	GO:0004857	enzyme inhibitor activity

0.72	GO:0019008	molybdopterin synthase complex
0.67	GO:0005829	cytosol

0.83

EC:2.8.1.12

GO:0030366

sp|P0CG69|UBIQP_DROME
Polyubiquitin
Search

0.45	Polyubiquitin

0.76	GO:0035096	larval midgut cell programmed cell death
0.69	GO:0007623	circadian rhythm
0.66	GO:0006914	autophagy
0.62	GO:0016567	protein ubiquitination

0.72

GO:0031386

protein tag

0.60	GO:0005654	nucleoplasm
0.59	GO:0005829	cytosol

sp|P0DKM0|COA3_DROME
Cytochrome c oxidase assembly factor 3, mitochondrial
Search

COA3

0.87	Cytochrome c oxidase assembly factor 3

0.59	GO:0097034	mitochondrial respiratory chain complex IV biogenesis
0.51	GO:0031167	rRNA methylation
0.46	GO:0070131	positive regulation of mitochondrial translation
0.45	GO:0008535	respiratory chain complex IV assembly
0.44	GO:0033108	mitochondrial respiratory chain complex assembly

0.55	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity
0.45	GO:0003723	RNA binding

0.48	GO:0005739	mitochondrion
0.43	GO:0031301	integral component of organelle membrane
0.40	GO:0031967	organelle envelope

0.55

GO:0000179

sp|P10035|HMH2_DROME
Homeobox protein H2.0
Search

0.92	Homeobox protein H2.0

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0045629	negative regulation of T-helper 2 cell differentiation
0.49	GO:0045627	positive regulation of T-helper 1 cell differentiation
0.48	GO:0048557	embryonic digestive tract morphogenesis
0.48	GO:0048484	enteric nervous system development
0.47	GO:0046622	positive regulation of organ growth
0.47	GO:0001889	liver development
0.46	GO:0007519	skeletal muscle tissue development

0.64	GO:0043565	sequence-specific DNA binding
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.32

GO:0016787

sp|P10040|CRB_DROME
Protein crumbs
Search

0.39	GO:0007219	Notch signaling pathway
0.38	GO:0030154	cell differentiation
0.37	GO:0050793	regulation of developmental process
0.33	GO:0006518	peptide metabolic process
0.33	GO:0043604	amide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:1901566	organonitrogen compound biosynthetic process
0.33	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process
0.32	GO:0106036	assembly of apicomedial cortex actomyosin

0.70	GO:0005509	calcium ion binding
0.35	GO:0008270	zinc ion binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0003723	RNA binding
0.32	GO:0005080	protein kinase C binding
0.32	GO:0030507	spectrin binding

0.34	GO:0015935	small ribosomal subunit
0.32	GO:0035003	subapical complex
0.32	GO:0016028	rhabdomere
0.32	GO:0005918	septate junction
0.32	GO:0016327	apicolateral plasma membrane
0.32	GO:0016324	apical plasma membrane
0.31	GO:0005819	spindle
0.30	GO:0016021	integral component of membrane

sp|P10041|DL_DROME
Neurogenic locus protein delta
Search

0.86	Delta, isoform B

0.78	GO:0007219	Notch signaling pathway
0.69	GO:0007275	multicellular organism development
0.55	GO:0046331	lateral inhibition
0.55	GO:0030720	oocyte localization involved in germarium-derived egg chamber formation
0.55	GO:0030713	ovarian follicle cell stalk formation
0.53	GO:0030718	germ-line stem cell population maintenance
0.53	GO:0007298	border follicle cell migration
0.52	GO:0007498	mesoderm development
0.51	GO:0048863	stem cell differentiation
0.51	GO:0051961	negative regulation of nervous system development

0.69	GO:0005509	calcium ion binding
0.53	GO:0005112	Notch binding
0.38	GO:0005044	scavenger receptor activity
0.32	GO:0003677	DNA binding
0.31	GO:0016787	hydrolase activity
0.31	GO:0016740	transferase activity

0.55	GO:0035003	subapical complex
0.51	GO:0030139	endocytic vesicle
0.50	GO:0005912	adherens junction
0.48	GO:0009986	cell surface
0.48	GO:0005768	endosome
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.31

GO:0016787

sp|P10083|AST5_DROME
Achaete-scute complex protein T5
Search

0.91	Lethal of scute

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.65	GO:0061382	Malpighian tubule tip cell differentiation
0.62	GO:0061331	epithelial cell proliferation involved in Malpighian tubule morphogenesis
0.60	GO:0008407	chaeta morphogenesis
0.56	GO:0007400	neuroblast fate determination
0.56	GO:0007422	peripheral nervous system development
0.54	GO:0002805	regulation of antimicrobial peptide biosynthetic process
0.48	GO:0045893	positive regulation of transcription, DNA-templated
0.44	GO:0035883	enteroendocrine cell differentiation
0.43	GO:0007530	sex determination

0.68	GO:0046983	protein dimerization activity
0.55	GO:0003677	DNA binding
0.50	GO:0001067	regulatory region nucleic acid binding
0.43	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.41	GO:0008134	transcription factor binding
0.40	GO:0042802	identical protein binding

0.54	GO:0005667	transcription factor complex
0.45	GO:0005634	nucleus
0.36	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P10084|AST4_DROME
Achaete-scute complex protein T4
Search

0.97	Achaete-scute complex protein T4

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.64	GO:0061382	Malpighian tubule tip cell differentiation
0.64	GO:0007400	neuroblast fate determination
0.61	GO:0008407	chaeta morphogenesis
0.58	GO:0035883	enteroendocrine cell differentiation
0.56	GO:0007422	peripheral nervous system development
0.56	GO:0007530	sex determination
0.54	GO:0045893	positive regulation of transcription, DNA-templated
0.53	GO:0043066	negative regulation of apoptotic process
0.52	GO:0006366	transcription by RNA polymerase II

0.68	GO:0046983	protein dimerization activity
0.56	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.55	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0008134	transcription factor binding
0.38	GO:0042802	identical protein binding

0.54	GO:0005667	transcription factor complex
0.38	GO:0005634	nucleus
0.35	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P10090|WHITE_DROME
Protein white
Search

WHITE

0.37	ABC membrane transporter

0.51	GO:0070731	cGMP transport
0.50	GO:0006856	eye pigment precursor transport
0.50	GO:0051615	histamine uptake
0.50	GO:1903716	guanine transmembrane transport
0.49	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle
0.49	GO:0033060	ocellus pigmentation
0.49	GO:0048072	compound eye pigmentation
0.49	GO:1903790	guanine nucleotide transmembrane transport
0.49	GO:0006726	eye pigment biosynthetic process
0.48	GO:0042332	gravitaxis

0.59	GO:0016887	ATPase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0015208	guanine transmembrane transporter activity
0.49	GO:0001409	guanine nucleotide transmembrane transporter activity
0.47	GO:0005346	purine ribonucleotide transmembrane transporter activity
0.44	GO:0005275	amine transmembrane transporter activity
0.43	GO:0031409	pigment binding
0.42	GO:0008514	organic anion transmembrane transporter activity

0.50	GO:0090740	integral component of pigment granule membrane
0.45	GO:0098793	presynapse
0.34	GO:0005886	plasma membrane

0.59

GO:0016887

sp|P10105|LAB_DROME
Homeotic protein labial
Search

LAB

0.96	Homeodomain transcription factor labial

0.61	GO:0035283	central nervous system segmentation
0.61	GO:0090098	positive regulation of decapentaplegic signaling pathway
0.58	GO:0060323	head morphogenesis
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0007420	brain development
0.51	GO:0051254	positive regulation of RNA metabolic process
0.51	GO:0010557	positive regulation of macromolecule biosynthetic process
0.51	GO:0031328	positive regulation of cellular biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.57	GO:0035326	enhancer binding
0.57	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.52	GO:0046982	protein heterodimerization activity
0.33	GO:0004000	adenosine deaminase activity
0.33	GO:0004743	pyruvate kinase activity
0.33	GO:0030955	potassium ion binding
0.32	GO:0000287	magnesium ion binding
0.32	GO:0016301	kinase activity

0.61	GO:0005634	nucleus
0.31	GO:0005737	cytoplasm

0.33

GO:0004000

sp|P10180|CUT_DROME
Homeobox protein cut
Search

0.64	Homeobox protein cut

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0006351	transcription, DNA-templated
0.56	GO:0010468	regulation of gene expression
0.48	GO:0061332	Malpighian tubule bud morphogenesis
0.48	GO:0060288	formation of a compartment boundary
0.48	GO:0048098	antennal joint development
0.47	GO:0030713	ovarian follicle cell stalk formation
0.47	GO:0070983	dendrite guidance
0.47	GO:0035277	spiracle morphogenesis, open tracheal system

0.64	GO:0043565	sequence-specific DNA binding
0.44	GO:0001012	RNA polymerase II regulatory region DNA binding
0.43	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.43	GO:0000139	Golgi membrane
0.32	GO:0000428	DNA-directed RNA polymerase complex
0.32	GO:0005667	transcription factor complex
0.32	GO:0043233	organelle lumen

sp|P10181|ROUGH_DROME
Homeobox protein rough
Search

0.96	Homeobox protein rough

0.63	GO:0007463	R2/R5 cell fate commitment
0.58	GO:0042067	establishment of ommatidial planar polarity
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:1902680	positive regulation of RNA biosynthetic process
0.43	GO:0045680	negative regulation of R8 cell differentiation
0.42	GO:0045464	R8 cell fate specification
0.41	GO:0007601	visual perception
0.37	GO:0001712	ectodermal cell fate commitment

0.64	GO:0043565	sequence-specific DNA binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.36	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.35	GO:0003690	double-stranded DNA binding
0.34	GO:0004000	adenosine deaminase activity
0.33	GO:0004640	phosphoribosylanthranilate isomerase activity
0.33	GO:0004425	indole-3-glycerol-phosphate synthase activity
0.32	GO:0003735	structural constituent of ribosome
0.32	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.35	GO:0000793	condensed chromosome
0.34	GO:0043233	organelle lumen
0.34	GO:0000776	kinetochore
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.34	EC:3.5.4.4	GO:0004000
0.33	KEGG:R03509	GO:0004640

sp|P10333|MS2A_DROME
Accessory gland-specific peptide 26Aa
Search

ACP26AA

0.97	Accessory gland-specific peptide 26Aa

0.85	GO:0007618	mating
0.66	GO:0030728	ovulation
0.50	GO:0007610	behavior
0.46	GO:0048042	regulation of post-mating oviposition
0.42	GO:0044706	multi-multicellular organism process

0.56

GO:0042802

identical protein binding

0.66

GO:0005576

extracellular region

sp|P10334|MS2B_DROME
Accessory gland-specific peptide 26Ab
Search

ACP26AB

0.97	Accessory gland-specific peptide 26Ab

0.85

GO:0007617

mating behavior

0.66

GO:0005576

extracellular region

sp|P10351|XDH_DROME
Xanthine dehydrogenase
Search

XDH

0.43	Molybdopterin-binding domain of aldehyde dehydrogenase

0.59	GO:0045471	response to ethanol
0.58	GO:0008340	determination of adult lifespan
0.54	GO:0006144	purine nucleobase metabolic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0006206	pyrimidine nucleobase metabolic process
0.52	GO:0006568	tryptophan metabolic process
0.51	GO:0006525	arginine metabolic process
0.51	GO:0006650	glycerophospholipid metabolic process
0.49	GO:0006091	generation of precursor metabolites and energy
0.40	GO:0046113	nucleobase catabolic process

0.68	GO:0043546	molybdopterin cofactor binding
0.64	GO:0016727	oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor
0.63	GO:0004854	xanthine dehydrogenase activity
0.61	GO:0050660	flavin adenine dinucleotide binding
0.60	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.56	GO:0051537	2 iron, 2 sulfur cluster binding
0.51	GO:0005506	iron ion binding
0.50	GO:0009055	electron transfer activity
0.38	GO:0003908	methylated-DNA-[protein]-cysteine S-methyltransferase activity
0.37	GO:0030151	molybdenum ion binding

0.40	GO:0005777	peroxisome
0.34	GO:0005829	cytosol

0.64

EC:1.17.3

GO:0016727

sp|P10379|UZIP_DROME
Protein unzipped
Search

0.96

Unzipped

0.77	GO:0007413	axonal fasciculation
0.71	GO:0007411	axon guidance

0.30

GO:0044425

membrane part

sp|P10383|OTU_DROME
Protein ovarian tumor locus
Search

0.85	GO:0032877	positive regulation of DNA endoreduplication
0.54	GO:0019099	female germ-line sex determination
0.48	GO:0048477	oogenesis
0.47	GO:0016579	protein deubiquitination
0.41	GO:0006468	protein phosphorylation
0.36	GO:0007155	cell adhesion

0.48	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.41	GO:0004672	protein kinase activity
0.39	GO:0030554	adenyl nucleotide binding
0.38	GO:0032555	purine ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0051015	actin filament binding
0.35	GO:0005198	structural molecule activity

0.47	GO:0005737	cytoplasm
0.36	GO:0015629	actin cytoskeleton
0.30	GO:0016020	membrane

sp|P10552|FMRF_DROME
FMRFamide-related peptides
Search

0.96	FMRFamide-related peptides

0.80	GO:0007218	neuropeptide signaling pathway
0.76	GO:1900075	positive regulation of neuromuscular synaptic transmission
0.73	GO:0010459	negative regulation of heart rate
0.72	GO:0008345	larval locomotory behavior
0.71	GO:0002209	behavioral defense response
0.69	GO:0006942	regulation of striated muscle contraction
0.68	GO:0008344	adult locomotory behavior
0.41	GO:0010469	regulation of receptor activity
0.33	GO:0005975	carbohydrate metabolic process

0.71	GO:0071855	neuropeptide receptor binding
0.42	GO:0005179	hormone activity
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.61

GO:0005615

extracellular space

0.33

GO:0004553

sp|P10627|TWIST_DROME
Protein twist
Search

TWI

0.85	Twist, isoform C

0.66	GO:0007370	ventral furrow formation
0.65	GO:0001710	mesodermal cell fate commitment
0.65	GO:0007443	Malpighian tubule morphogenesis
0.63	GO:0007435	salivary gland morphogenesis
0.62	GO:0048747	muscle fiber development
0.62	GO:0016202	regulation of striated muscle tissue development
0.61	GO:0031032	actomyosin structure organization
0.56	GO:0045944	positive regulation of transcription by RNA polymerase II
0.52	GO:0010629	negative regulation of gene expression
0.42	GO:0007499	ectoderm and mesoderm interaction

0.68	GO:0046983	protein dimerization activity
0.62	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.56	GO:0042802	identical protein binding
0.45	GO:0003677	DNA binding
0.33	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.33	GO:0003682	chromatin binding
0.33	GO:0019904	protein domain specific binding

0.49	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm
0.33	GO:0043233	organelle lumen
0.33	GO:0005667	transcription factor complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0044446	intracellular organelle part

sp|P10674|FAS1_DROME
Fasciclin-1
Search

0.92	Fasciclin-1

0.55	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.54	GO:0030198	extracellular matrix organization
0.53	GO:0008038	neuron recognition
0.51	GO:0007411	axon guidance
0.50	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

0.50

GO:0050839

cell adhesion molecule binding

0.54	GO:0031225	anchored component of membrane
0.51	GO:0005578	proteinaceous extracellular matrix
0.50	GO:0005615	extracellular space
0.43	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P10676|NINAC_DROME
Neither inactivation nor afterpotential protein C
Search

0.68	Neither inactivation nor afterpotential protein C

0.69	GO:0018108	peptidyl-tyrosine phosphorylation
0.60	GO:1990146	protein localization to rhabdomere
0.59	GO:0007604	phototransduction, UV
0.59	GO:0016062	adaptation of rhodopsin mediated signaling
0.58	GO:0016059	deactivation of rhodopsin mediated signaling
0.57	GO:0007018	microtubule-based movement
0.56	GO:0045494	photoreceptor cell maintenance
0.56	GO:0033227	dsRNA transport
0.49	GO:0007010	cytoskeleton organization
0.48	GO:0006886	intracellular protein transport

0.73	GO:0003779	actin binding
0.72	GO:0003774	motor activity
0.69	GO:0004713	protein tyrosine kinase activity
0.58	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0005516	calmodulin binding
0.51	GO:0035091	phosphatidylinositol binding
0.49	GO:0004674	protein serine/threonine kinase activity

0.76	GO:0016459	myosin complex
0.59	GO:0033583	rhabdomere membrane
0.58	GO:0016027	inaD signaling complex
0.44	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.38	GO:0032433	filopodium tip
0.38	GO:0031941	filamentous actin
0.35	GO:0005578	proteinaceous extracellular matrix

0.69

GO:0004713

sp|P10734|KNIR_DROME
Zygotic gap protein knirps
Search

KNI

0.93	Zygotic gap protein knirps

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0007088	regulation of mitotic nuclear division
0.51	GO:1902679	negative regulation of RNA biosynthetic process
0.41	GO:0046845	branched duct epithelial cell fate determination, open tracheal system
0.40	GO:0007427	epithelial cell migration, open tracheal system
0.40	GO:0007417	central nervous system development
0.40	GO:0035151	regulation of tube size, open tracheal system

0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0070491	repressing transcription factor binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P10735|RT12_DROME
40S ribosomal protein S12, mitochondrial
Search

0.38	Technical knockout

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.37	GO:0008654	phospholipid biosynthetic process
0.36	GO:0007638	mechanosensory behavior
0.36	GO:0008049	male courtship behavior
0.35	GO:0001666	response to hypoxia
0.35	GO:0007605	sensory perception of sound

0.64	GO:0003735	structural constituent of ribosome
0.37	GO:0016780	phosphotransferase activity, for other substituted phosphate groups
0.33	GO:0000049	tRNA binding
0.32	GO:0016746	transferase activity, transferring acyl groups
0.32	GO:0019843	rRNA binding

0.70	GO:0015935	small ribosomal subunit
0.39	GO:0005761	mitochondrial ribosome
0.30	GO:0016020	membrane

0.37

EC:2.7.8

GO:0016780

sp|P10981|ACT5_DROME
Actin-87E
Search

0.48	Actin, indirect flight muscle

0.47	GO:0055002	striated muscle cell development
0.44	GO:0007528	neuromuscular junction development
0.43	GO:0014902	myotube differentiation
0.43	GO:0043486	histone exchange
0.43	GO:0007519	skeletal muscle tissue development
0.43	GO:0050807	regulation of synapse organization
0.43	GO:0000281	mitotic cytokinesis
0.42	GO:0016573	histone acetylation
0.41	GO:0031032	actomyosin structure organization
0.41	GO:0010927	cellular component assembly involved in morphogenesis

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005200	structural constituent of cytoskeleton

0.42	GO:0035267	NuA4 histone acetyltransferase complex
0.38	GO:0005856	cytoskeleton
0.35	GO:0099512	supramolecular fiber
0.34	GO:0005737	cytoplasm
0.32	GO:0005886	plasma membrane

sp|P10987|ACT1_DROME
Actin-5C
Search

0.47	Alpha-actin

0.36	GO:0000281	mitotic cytokinesis
0.35	GO:0007291	sperm individualization
0.34	GO:0035148	tube formation
0.34	GO:0032507	maintenance of protein location in cell
0.34	GO:0006338	chromatin remodeling
0.33	GO:0007010	cytoskeleton organization

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0005515	protein binding

0.37	GO:0005856	cytoskeleton
0.37	GO:0035060	brahma complex
0.35	GO:0097433	dense body
0.34	GO:0005925	focal adhesion
0.34	GO:0031011	Ino80 complex
0.33	GO:0099512	supramolecular fiber
0.32	GO:0005886	plasma membrane

sp|P11046|LAMB1_DROME
Laminin subunit beta-1
Search

0.67	Laminin subunit beta-1 (inferred by orthology to a human protein)

0.71	GO:0070831	basement membrane assembly
0.70	GO:0033627	cell adhesion mediated by integrin
0.69	GO:0055013	cardiac muscle cell development
0.69	GO:0034446	substrate adhesion-dependent cell spreading
0.68	GO:0003143	embryonic heart tube morphogenesis
0.66	GO:0008406	gonad development
0.63	GO:0016477	cell migration
0.48	GO:0050829	defense response to Gram-negative bacterium
0.48	GO:0045089	positive regulation of innate immune response
0.40	GO:0018108	peptidyl-tyrosine phosphorylation

0.44	GO:0003944	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity
0.41	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.34	GO:0005230	extracellular ligand-gated ion channel activity
0.33	GO:0003777	microtubule motor activity
0.33	GO:0003676	nucleic acid binding
0.33	GO:0016887	ATPase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.70	GO:0005605	basal lamina
0.34	GO:0030286	dynein complex
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.44

EC:3.1.4.45

GO:0003944

sp|P11146|HSP7B_DROME
Heat shock 70 kDa protein cognate 2
Search

0.60	Heat shock protein cognate 2

0.41	GO:0008340	determination of adult lifespan
0.40	GO:0042594	response to starvation
0.35	GO:0006457	protein folding
0.34	GO:0010918	positive regulation of mitochondrial membrane potential
0.34	GO:0070584	mitochondrion morphogenesis
0.34	GO:0000422	autophagy of mitochondrion
0.33	GO:0055114	oxidation-reduction process

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.35	GO:0051082	unfolded protein binding
0.33	GO:0043565	sequence-specific DNA binding

0.34	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.36

GO:0032440

sp|P11147|HSP7D_DROME
Heat shock 70 kDa protein cognate 4
Search

0.59	Heat shock protein cognate 4

0.47	GO:0061738	late endosomal microautophagy
0.45	GO:0070868	heterochromatin organization involved in chromatin silencing
0.45	GO:0007413	axonal fasciculation
0.45	GO:0001700	embryonic development via the syncytial blastoderm
0.44	GO:0016246	RNA interference
0.44	GO:0030707	ovarian follicle cell development
0.44	GO:0099643	signal release from synapse
0.44	GO:0035967	cellular response to topologically incorrect protein
0.44	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.43	GO:0007411	axon guidance

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0051087	chaperone binding
0.38	GO:0004672	protein kinase activity
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0051082	unfolded protein binding

0.46	GO:0005726	perichromatin fibrils
0.44	GO:0030018	Z disc
0.43	GO:0098793	presynapse
0.38	GO:0031966	mitochondrial membrane
0.38	GO:0019866	organelle inner membrane
0.35	GO:0071011	precatalytic spliceosome
0.34	GO:0071013	catalytic step 2 spliceosome
0.34	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016021	integral component of membrane

0.34

GO:0032440

sp|P11346|KRAF1_DROME
Raf homolog serine/threonine-protein kinase phl
Search

BRAF

0.75	RAF proto-oncogene serine/threonine-protein kinase

0.63	GO:0006468	protein phosphorylation
0.61	GO:0035556	intracellular signal transduction
0.55	GO:0035171	lamellocyte differentiation
0.54	GO:0008069	dorsal/ventral axis specification, ovarian follicular epithelium
0.54	GO:0046534	positive regulation of photoreceptor cell differentiation
0.54	GO:0035309	wing and notum subfield formation
0.53	GO:0007362	terminal region determination
0.53	GO:0008293	torso signaling pathway
0.53	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.52	GO:0002168	instar larval development

0.76	GO:0005057	signal transducer activity, downstream of receptor
0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.42	GO:0031434	mitogen-activated protein kinase kinase binding
0.39	GO:0042802	identical protein binding
0.37	GO:0046332	SMAD binding

0.44	GO:0005622	intracellular
0.39	GO:0044297	cell body
0.38	GO:0043005	neuron projection
0.37	GO:0005886	plasma membrane
0.36	GO:0043227	membrane-bounded organelle
0.34	GO:0031143	pseudopodium
0.33	GO:0012505	endomembrane system
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044422	organelle part
0.30	GO:0016021	integral component of membrane

0.69

GO:0004674

sp|P11420|DA_DROME
Protein daughterless
Search

0.70	Putative helix loop helix transcription factor

0.62	GO:0061382	Malpighian tubule tip cell differentiation
0.62	GO:0030237	female sex determination
0.62	GO:0007400	neuroblast fate determination
0.62	GO:0061101	neuroendocrine cell differentiation
0.61	GO:0008407	chaeta morphogenesis
0.60	GO:0035019	somatic stem cell population maintenance
0.59	GO:0048663	neuron fate commitment
0.57	GO:0048477	oogenesis
0.54	GO:0006366	transcription by RNA polymerase II
0.54	GO:0045944	positive regulation of transcription by RNA polymerase II

0.68	GO:0046983	protein dimerization activity
0.57	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.53	GO:0042802	identical protein binding
0.52	GO:0008134	transcription factor binding
0.40	GO:0000987	proximal promoter sequence-specific DNA binding

0.53	GO:0005667	transcription factor complex
0.46	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P11449|VTU1_DROME
Vitelline membrane protein Vm26Aa
Search

0.87	GO:0007305	vitelline membrane formation involved in chorion-containing eggshell formation
0.60	GO:0007343	egg activation
0.54	GO:0009617	response to bacterium
0.36	GO:0009950	dorsal/ventral axis specification
0.35	GO:0045292	mRNA cis splicing, via spliceosome

0.59	GO:0008316	structural constituent of vitelline membrane
0.35	GO:0000339	RNA cap binding
0.34	GO:0004386	helicase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.85	GO:0060388	vitelline envelope
0.49	GO:0005576	extracellular region
0.35	GO:0005846	nuclear cap binding complex
0.30	GO:0016020	membrane

sp|P11450|FCP3C_DROME
Follicle cell protein 3C-1
Search

0.86	Follicle cell protein 3C-1

0.43

GO:0006468

protein phosphorylation

0.43	GO:0004672	protein kinase activity
0.39	GO:0030554	adenyl nucleotide binding
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

sp|P11455|TERM_DROME
Protein terminus
Search

0.42

GO:0007275

multicellular organism development

0.51	GO:0003676	nucleic acid binding
0.37	GO:0046872	metal ion binding

sp|P11536|E74EB_DROME
Ecdysone-induced protein 74EF isoform B
Search

EIP74EF

0.84	Ecdysone-induced protein 74EF isoform B

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0035071	salivary gland cell autophagic cell death
0.49	GO:0006914	autophagy
0.49	GO:0006366	transcription by RNA polymerase II
0.48	GO:1902680	positive regulation of RNA biosynthetic process
0.43	GO:0040034	regulation of development, heterochronic
0.41	GO:0048477	oogenesis
0.33	GO:0001787	natural killer cell proliferation

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005267	potassium channel activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P11584|ITBX_DROME
Integrin beta-PS
Search

0.70	Integrin beta

0.80	GO:0007229	integrin-mediated signaling pathway
0.72	GO:0007155	cell adhesion
0.39	GO:0007508	larval heart development
0.38	GO:0035001	dorsal trunk growth, open tracheal system
0.38	GO:0007377	germ-band extension
0.38	GO:0035160	maintenance of epithelial integrity, open tracheal system
0.38	GO:0006930	substrate-dependent cell migration, cell extension
0.38	GO:0048803	imaginal disc-derived male genitalia morphogenesis
0.38	GO:0090129	positive regulation of synapse maturation
0.38	GO:0035099	hemocyte migration

0.38	GO:1990430	extracellular matrix protein binding
0.36	GO:0046982	protein heterodimerization activity
0.30	GO:0050839	cell adhesion molecule binding
0.30	GO:0004872	receptor activity

0.38	GO:0005927	muscle tendon junction
0.38	GO:0043034	costamere
0.38	GO:0009925	basal plasma membrane
0.38	GO:0042734	presynaptic membrane
0.37	GO:0016328	lateral plasma membrane
0.37	GO:0005925	focal adhesion
0.37	GO:0008305	integrin complex
0.37	GO:0030425	dendrite
0.37	GO:0031252	cell leading edge
0.37	GO:0045211	postsynaptic membrane

sp|P11596|TRSF_DROME
Female-specific protein transformer
Search

TRA

0.95	Female-specific protein transformer

0.71	GO:0046660	female sex differentiation
0.69	GO:0030237	female sex determination
0.68	GO:0045433	male courtship behavior, veined wing generated song production
0.66	GO:0006397	mRNA processing
0.63	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
0.49	GO:0022618	ribonucleoprotein complex assembly
0.45	GO:0030154	cell differentiation
0.43	GO:0018993	somatic sex determination
0.42	GO:0043484	regulation of RNA splicing
0.41	GO:0017148	negative regulation of translation

0.64	GO:0036002	pre-mRNA binding
0.48	GO:0003729	mRNA binding
0.38	GO:0005515	protein binding
0.38	GO:0046872	metal ion binding
0.38	GO:0030882	lipid antigen binding
0.36	GO:0001530	lipopolysaccharide binding
0.34	GO:0016301	kinase activity
0.34	GO:0018024	histone-lysine N-methyltransferase activity
0.33	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.58	GO:0005634	nucleus
0.48	GO:0120114	Sm-like protein family complex
0.44	GO:0044446	intracellular organelle part
0.43	GO:0031974	membrane-enclosed lumen
0.41	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0048786	presynaptic active zone
0.33	GO:0005694	chromosome
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.34

GO:0018024

sp|P11612|PPY_DROME
Serine/threonine-protein phosphatase PP-Y
Search

0.49	Diadenosine tetraphosphatase

0.72	GO:0006470	protein dephosphorylation
0.49	GO:1905213	negative regulation of mitotic chromosome condensation
0.49	GO:0090233	negative regulation of spindle checkpoint
0.48	GO:0051315	attachment of mitotic spindle microtubules to kinetochore
0.48	GO:0045842	positive regulation of mitotic metaphase/anaphase transition
0.48	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint
0.39	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.38	GO:0090029	negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
0.35	GO:0019953	sexual reproduction
0.35	GO:1904886	beta-catenin destruction complex disassembly

0.72	GO:0004721	phosphoprotein phosphatase activity
0.52	GO:0046872	metal ion binding
0.35	GO:0048037	cofactor binding
0.33	GO:0005515	protein binding

0.67	GO:0000164	protein phosphatase type 1 complex
0.52	GO:0072357	PTW/PP1 phosphatase complex
0.49	GO:1990567	DPS complex
0.49	GO:0035839	non-growing cell tip
0.49	GO:0061638	CENP-A containing chromatin
0.48	GO:0035838	growing cell tip
0.47	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex
0.46	GO:0030139	endocytic vesicle
0.44	GO:0000790	nuclear chromatin
0.44	GO:0005938	cell cortex

0.72

GO:0004721

sp|P11929|BSG2_DROME
Blastoderm-specific protein 25D
Search

BSG25D

0.79	Blastoderm-specific protein 25D

0.80	GO:0034994	microtubule organizing center attachment site organization
0.58	GO:0007275	multicellular organism development
0.46	GO:0016192	vesicle-mediated transport
0.39	GO:0005992	trehalose biosynthetic process
0.37	GO:0007018	microtubule-based movement
0.36	GO:0006487	protein N-linked glycosylation
0.36	GO:0097502	mannosylation
0.35	GO:0006633	fatty acid biosynthetic process

0.62	GO:0008017	microtubule binding
0.52	GO:0005509	calcium ion binding
0.38	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.38	GO:0051015	actin filament binding
0.38	GO:0003777	microtubule motor activity
0.37	GO:0000009	alpha-1,6-mannosyltransferase activity
0.37	GO:0102756	very-long-chain 3-ketoacyl-CoA synthase activity
0.37	GO:0102338	3-oxo-lignoceronyl-CoA synthase activity
0.37	GO:0102336	3-oxo-arachidoyl-CoA synthase activity
0.37	GO:0102337	3-oxo-cerotoyl-CoA synthase activity

0.70	GO:0000242	pericentriolar material
0.38	GO:0016459	myosin complex
0.37	GO:0000136	alpha-1,6-mannosyltransferase complex

0.37

EC:2.4.1

GO:0000009

sp|P11956|MT2_DROME
Metallothionein-2
Search

0.86	Metallothionein B

0.65	GO:0010038	response to metal ion
0.63	GO:0055065	metal ion homeostasis

0.54	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding

sp|P11995|LSP1A_DROME
Larval serum protein 1 alpha chain
Search

0.91	Larval serum protein 1 alpha chain

0.54

GO:0045735

nutrient reservoir activity

0.87	GO:0005616	larval serum protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P11996|LSP1B_DROME
Larval serum protein 1 beta chain
Search

0.85	Arylphorin subunit alpha

0.52

GO:0045735

nutrient reservoir activity

0.87	GO:0005616	larval serum protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P11997|LSP1G_DROME
Larval serum protein 1 gamma chain
Search

0.88	Larval serum protein 1 gamma chain

0.51

GO:0045735

nutrient reservoir activity

0.87	GO:0005616	larval serum protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P12024|CHAO_DROME
Chaoptin
Search

CHP

0.45	LOW QUALITY PROTEIN: chaoptin

0.41	GO:0032528	microvillus organization
0.41	GO:0042052	rhabdomere development
0.40	GO:0007601	visual perception
0.39	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.39	GO:0007093	mitotic cell cycle checkpoint
0.37	GO:0006468	protein phosphorylation
0.36	GO:0050896	response to stimulus
0.34	GO:0006470	protein dephosphorylation
0.33	GO:0060271	cilium assembly
0.32	GO:0051239	regulation of multicellular organismal process

0.37	GO:0004672	protein kinase activity
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0008144	drug binding
0.34	GO:0004721	phosphoprotein phosphatase activity
0.32	GO:0005496	steroid binding
0.32	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0004871	signal transducer activity
0.32	GO:0099600	transmembrane receptor activity

0.42	GO:0035996	rhabdomere microvillus
0.40	GO:1990423	RZZ complex
0.40	GO:0046658	anchored component of plasma membrane
0.33	GO:0031012	extracellular matrix
0.32	GO:0005768	endosome
0.32	GO:0030015	CCR4-NOT core complex
0.32	GO:1905360	GTPase complex
0.32	GO:0016593	Cdc73/Paf1 complex
0.32	GO:0000932	P-body
0.32	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane

0.34	EC:3.1.3.16	GO:0004721
0.32	KEGG:R03876	GO:0004842

sp|P12080|ITA2_DROME
Integrin alpha-PS2
Search

0.78	Integrin alpha

0.80	GO:0007229	integrin-mediated signaling pathway
0.72	GO:0007155	cell adhesion
0.56	GO:0035160	maintenance of epithelial integrity, open tracheal system
0.56	GO:0007414	axonal defasciculation
0.56	GO:0035099	hemocyte migration
0.55	GO:0021551	central nervous system morphogenesis
0.55	GO:0007419	ventral cord development
0.55	GO:0016203	muscle attachment
0.54	GO:0007298	border follicle cell migration
0.53	GO:0007435	salivary gland morphogenesis

0.56	GO:1990430	extracellular matrix protein binding
0.53	GO:0050840	extracellular matrix binding
0.48	GO:0046982	protein heterodimerization activity
0.38	GO:0050839	cell adhesion molecule binding
0.36	GO:0004872	receptor activity
0.32	GO:0016301	kinase activity
0.32	GO:0004871	signal transducer activity
0.31	GO:0046872	metal ion binding

0.80	GO:0008305	integrin complex
0.54	GO:0009925	basal plasma membrane
0.53	GO:0042383	sarcolemma
0.52	GO:0005925	focal adhesion
0.39	GO:0016328	lateral plasma membrane
0.38	GO:0016324	apical plasma membrane
0.33	GO:0009986	cell surface
0.33	GO:0055120	striated muscle dense body
0.33	GO:0031430	M band

sp|P12297|SUWA_DROME
Protein suppressor of white apricot
Search

SU(W[A])

0.81	Suppressor of white-apricot

0.63	GO:0006396	RNA processing
0.42	GO:0022618	ribonucleoprotein complex assembly
0.41	GO:0016071	mRNA metabolic process
0.40	GO:0019310	inositol catabolic process
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.35	GO:0055114	oxidation-reduction process
0.33	GO:1903312	negative regulation of mRNA metabolic process

0.59	GO:0003723	RNA binding
0.41	GO:0050113	inositol oxygenase activity
0.36	GO:0005506	iron ion binding
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding

0.39	GO:0016607	nuclear speck
0.34	GO:0005737	cytoplasm
0.33	GO:0031012	extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

0.41	EC:1.13.99.1	GO:0050113
0.41	KEGG:R01184	GO:0050113

sp|P12370|KAPC_DROME
cAMP-dependent protein kinase catalytic subunit
Search

0.57	cAMP-dependent protein kinase catalytic subunit alpha

0.63	GO:0006468	protein phosphorylation
0.43	GO:0008359	regulation of bicoid mRNA localization
0.42	GO:0048682	sprouting of injured axon
0.42	GO:0007615	anesthesia-resistant memory
0.42	GO:0007228	positive regulation of hh target transcription factor activity
0.42	GO:0007448	anterior/posterior pattern specification, imaginal disc
0.42	GO:0008103	oocyte microtubule cytoskeleton polarization
0.42	GO:0045879	negative regulation of smoothened signaling pathway
0.42	GO:0007317	regulation of pole plasm oskar mRNA localization
0.41	GO:0040040	thermosensory behavior

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0060089	molecular transducer activity
0.34	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0000287	magnesium ion binding

0.40	GO:0030425	dendrite
0.40	GO:0044297	cell body
0.35	GO:0005886	plasma membrane
0.34	GO:0005952	cAMP-dependent protein kinase complex
0.34	GO:0097546	ciliary base
0.34	GO:0005829	cytosol
0.34	GO:0045171	intercellular bridge
0.34	GO:0005813	centrosome
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004674

sp|P12426|APT_DROME
Adenine phosphoribosyltransferase
Search

APRT

0.42	Adenine phosphoribosyl transferases

0.78	GO:0006168	adenine salvage
0.66	GO:0009116	nucleoside metabolic process
0.59	GO:0044209	AMP salvage
0.55	GO:1901659	glycosyl compound biosynthetic process
0.43	GO:0007625	grooming behavior
0.34	GO:0043312	neutrophil degranulation
0.34	GO:0007595	lactation
0.33	GO:0032869	cellular response to insulin stimulus
0.32	GO:0009174	pyrimidine ribonucleoside monophosphate biosynthetic process
0.32	GO:0009218	pyrimidine ribonucleotide metabolic process

0.78	GO:0003999	adenine phosphoribosyltransferase activity
0.44	GO:0002055	adenine binding
0.41	GO:0016208	AMP binding
0.33	GO:0017061	S-methyl-5-thioadenosine phosphorylase activity
0.33	GO:0008484	sulfuric ester hydrolase activity
0.32	GO:0004588	orotate phosphoribosyltransferase activity
0.32	GO:0046872	metal ion binding

0.48	GO:0005737	cytoplasm
0.39	GO:0005654	nucleoplasm
0.34	GO:0097311	biofilm matrix
0.34	GO:0031983	vesicle lumen
0.33	GO:0070062	extracellular exosome
0.33	GO:0097708	intracellular vesicle
0.32	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:2.4.2.7

GO:0003999

sp|P12428|BROWN_DROME
Protein brown
Search

0.86

Brown

0.43	GO:0033060	ocellus pigmentation
0.43	GO:0006726	eye pigment biosynthetic process
0.43	GO:0006856	eye pigment precursor transport
0.43	GO:0055085	transmembrane transport
0.42	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle
0.40	GO:0044550	secondary metabolite biosynthetic process
0.39	GO:0030301	cholesterol transport
0.39	GO:0007605	sensory perception of sound
0.37	GO:0006506	GPI anchor biosynthetic process
0.36	GO:0018130	heterocycle biosynthetic process

0.60	GO:0016887	ATPase activity
0.54	GO:0005524	ATP binding
0.43	GO:0031409	pigment binding
0.40	GO:0017127	cholesterol transporter activity
0.39	GO:0005275	amine transmembrane transporter activity
0.38	GO:1901618	organic hydroxy compound transmembrane transporter activity
0.38	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity
0.38	GO:0015399	primary active transmembrane transporter activity
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0015604	organic phosphonate transmembrane transporter activity

0.40	GO:0098793	presynapse
0.37	GO:0090740	integral component of pigment granule membrane
0.35	GO:0005886	plasma membrane
0.33	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0012505	endomembrane system
0.32	GO:0098805	whole membrane
0.32	GO:0031984	organelle subcompartment

0.60

GO:0016887

sp|P12613|TCPA_DROME
T-complex protein 1 subunit alpha
Search

0.59	T-complex protein subunit alpha

0.68	GO:0006457	protein folding
0.46	GO:0030707	ovarian follicle cell development
0.38	GO:0070121	Kupffer's vesicle development

0.70	GO:0051082	unfolded protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0044183	protein binding involved in protein folding
0.32	GO:0016740	transferase activity

0.47	GO:0005737	cytoplasm
0.41	GO:0101031	chaperone complex
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016740

sp|P12646|G6PD_DROME
Glucose-6-phosphate 1-dehydrogenase
Search

0.43	Glucose-6-phosphate 1-dehydrogenase

0.71	GO:0006006	glucose metabolic process
0.70	GO:0006098	pentose-phosphate shunt
0.53	GO:0055114	oxidation-reduction process
0.33	GO:0015074	DNA integration

0.79	GO:0004345	glucose-6-phosphate dehydrogenase activity
0.70	GO:0050661	NADP binding
0.32	GO:0003676	nucleic acid binding

0.30

GO:0031224

intrinsic component of membrane

0.79

EC:1.1.1.49

GO:0004345

sp|P12881|PSA1_DROME
Proteasome subunit alpha type-1
Search

0.49	Proteasome endopeptidase complex

0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.48	GO:0007370	ventral furrow formation
0.44	GO:0007290	spermatid nucleus elongation
0.44	GO:0007291	sperm individualization
0.36	GO:0010498	proteasomal protein catabolic process
0.36	GO:0008063	Toll signaling pathway
0.35	GO:0007623	circadian rhythm
0.34	GO:0050829	defense response to Gram-negative bacterium
0.34	GO:0045824	negative regulation of innate immune response

0.77	GO:0070003	threonine-type peptidase activity
0.65	GO:0004175	endopeptidase activity

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.60	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|P12982|PP12_DROME
Serine/threonine-protein phosphatase alpha-2 isoform
Search

0.52	Serine/threonine-protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.45	GO:0046692	sperm competition
0.44	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.42	GO:0008355	olfactory learning
0.42	GO:0008542	visual learning
0.41	GO:0007080	mitotic metaphase plate congression
0.41	GO:0008344	adult locomotory behavior
0.41	GO:0051225	spindle assembly
0.40	GO:0048477	oogenesis
0.40	GO:0007411	axon guidance

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.54	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding

0.84	GO:0000164	protein phosphatase type 1 complex
0.55	GO:0072357	PTW/PP1 phosphatase complex
0.41	GO:0005700	polytene chromosome
0.35	GO:0005829	cytosol
0.34	GO:0000784	nuclear chromosome, telomeric region
0.34	GO:0005741	mitochondrial outer membrane
0.33	GO:0005730	nucleolus
0.32	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P13002|ELF1_DROME
Protein grainyhead
Search

0.86	GO:0007464	R3/R4 cell fate commitment
0.86	GO:0007426	tracheal outgrowth, open tracheal system
0.86	GO:0008362	chitin-based embryonic cuticle biosynthetic process
0.85	GO:0035159	regulation of tube length, open tracheal system
0.85	GO:0042052	rhabdomere development
0.84	GO:0003382	epithelial cell morphogenesis
0.81	GO:0061041	regulation of wound healing
0.80	GO:0007009	plasma membrane organization
0.74	GO:0042127	regulation of cell proliferation
0.73	GO:0045944	positive regulation of transcription by RNA polymerase II

0.73	GO:0042803	protein homodimerization activity
0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.36	GO:0004252	serine-type endopeptidase activity

0.61

GO:0005634

nucleus

0.36

GO:0004252

sp|P13008|RS26_DROME
40S ribosomal protein S26
Search

0.65	40S ribosomal protein S26

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.37	GO:0033119	negative regulation of RNA splicing

0.64	GO:0003735	structural constituent of ribosome
0.42	GO:0003729	mRNA binding
0.37	GO:0045296	cadherin binding

0.61	GO:0005840	ribosome
0.46	GO:0044445	cytosolic part
0.40	GO:0044446	intracellular organelle part
0.40	GO:0005844	polysome
0.38	GO:0005791	rough endoplasmic reticulum
0.37	GO:0098562	cytoplasmic side of membrane
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0098588	bounding membrane of organelle
0.34	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|P13054|KNRL_DROME
Knirps-related protein
Search

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0007088	regulation of mitotic nuclear division
0.52	GO:1902679	negative regulation of RNA biosynthetic process
0.43	GO:0046845	branched duct epithelial cell fate determination, open tracheal system
0.42	GO:0007427	epithelial cell migration, open tracheal system
0.41	GO:0035151	regulation of tube size, open tracheal system
0.41	GO:0007417	central nervous system development

0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P13055|E75BB_DROME
Ecdysone-induced protein 75B, isoform B
Search

0.78	Nuclear receptor subfamily 1 group D member

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.76	GO:0030522	intracellular receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0007553	regulation of ecdysteroid metabolic process
0.49	GO:0018990	ecdysis, chitin-based cuticle
0.49	GO:0035075	response to ecdysone
0.48	GO:0019730	antimicrobial humoral response

0.82	GO:0004887	thyroid hormone receptor activity
0.79	GO:0003707	steroid hormone receptor activity
0.58	GO:0043565	sequence-specific DNA binding
0.57	GO:0008270	zinc ion binding
0.41	GO:0020037	heme binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P13060|EF2_DROME
Elongation factor 2
Search

0.41	Eukaryotic translation elongation factor

0.61

GO:0006414

translational elongation

0.67	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.62	GO:0003746	translation elongation factor activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0019013	viral nucleocapsid
0.35	GO:1990904	ribonucleoprotein complex
0.33	GO:0005829	cytosol

sp|P13095|ESM4_DROME
Enhancer of split m4 protein
Search

0.82	GO:0007219	Notch signaling pathway
0.79	GO:0007423	sensory organ development
0.70	GO:0001708	cell fate specification
0.39	GO:0007399	nervous system development

0.67

GO:0031625

ubiquitin protein ligase binding

0.37

GO:0005634

nucleus

sp|P13096|ESM5_DROME
Enhancer of split m5 protein
Search

0.80	Basic helix-loop-helix transcription factor

0.60	GO:0000122	negative regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.56	GO:0016360	sensory organ precursor cell fate determination
0.54	GO:0048749	compound eye development
0.53	GO:0048813	dendrite morphogenesis
0.53	GO:0007498	mesoderm development
0.37	GO:0007398	ectoderm development
0.37	GO:0008587	imaginal disc-derived wing margin morphogenesis
0.36	GO:0007173	epidermal growth factor receptor signaling pathway
0.36	GO:0007422	peripheral nervous system development

0.68	GO:0046983	protein dimerization activity
0.64	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.58	GO:0042802	identical protein binding
0.55	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P13097|ESM7_DROME
Enhancer of split m7 protein
Search

0.82	Enhancer of split region protein HLHmg

0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0002052	positive regulation of neuroblast proliferation
0.50	GO:0051253	negative regulation of RNA metabolic process
0.50	GO:0010558	negative regulation of macromolecule biosynthetic process
0.50	GO:0031327	negative regulation of cellular biosynthetic process
0.45	GO:0048190	wing disc dorsal/ventral pattern formation
0.45	GO:0097150	neuronal stem cell population maintenance

0.68	GO:0046983	protein dimerization activity
0.54	GO:0003677	DNA binding
0.51	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.49	GO:0008134	transcription factor binding
0.41	GO:0001067	regulatory region nucleic acid binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P13098|ESM8_DROME
Enhancer of split m8 protein
Search

0.81	Basic helix-loop-helix transcription factor

0.65	GO:0016360	sensory organ precursor cell fate determination
0.63	GO:0000122	negative regulation of transcription by RNA polymerase II
0.62	GO:0048813	dendrite morphogenesis
0.62	GO:0048749	compound eye development
0.61	GO:0007498	mesoderm development
0.58	GO:0006351	transcription, DNA-templated
0.39	GO:0007398	ectoderm development
0.39	GO:0008587	imaginal disc-derived wing margin morphogenesis
0.39	GO:0007173	epidermal growth factor receptor signaling pathway
0.38	GO:0007422	peripheral nervous system development

0.68	GO:0046983	protein dimerization activity
0.68	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.60	GO:0042802	identical protein binding
0.55	GO:0003677	DNA binding

0.61

GO:0005634

nucleus

sp|P13217|PIPA_DROME
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
Search

0.53	Phosphoinositide phospholipase C

0.72	GO:0016042	lipid catabolic process
0.63	GO:0035556	intracellular signal transduction
0.44	GO:0046673	negative regulation of compound eye retinal cell programmed cell death
0.44	GO:0016059	deactivation of rhodopsin mediated signaling
0.44	GO:2000370	positive regulation of clathrin-dependent endocytosis
0.43	GO:0043052	thermotaxis
0.43	GO:0016056	rhodopsin mediated signaling pathway
0.43	GO:0043153	entrainment of circadian clock by photoperiod
0.43	GO:0002385	mucosal immune response
0.43	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste

0.82	GO:0004435	phosphatidylinositol phospholipase C activity
0.68	GO:0005509	calcium ion binding
0.64	GO:0004871	signal transducer activity
0.35	GO:0005096	GTPase activator activity
0.33	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.44	GO:0016027	inaD signaling complex

0.82	EC:3.1.4.11	GO:0004435
0.82	KEGG:R03435	GO:0004435

sp|P13238|VTU2_DROME
Vitelline membrane protein Vm26Ab
Search

VM26AB

0.40	Low-density lipoprotein receptor-related protein 4 (Fragment)

0.85	GO:0007305	vitelline membrane formation involved in chorion-containing eggshell formation
0.76	GO:0007343	egg activation
0.67	GO:0009617	response to bacterium
0.49	GO:0009950	dorsal/ventral axis specification
0.35	GO:0051301	cell division
0.35	GO:0007049	cell cycle
0.34	GO:0007059	chromosome segregation
0.33	GO:0071897	DNA biosynthetic process
0.33	GO:0006260	DNA replication

0.46	GO:0008316	structural constituent of vitelline membrane
0.34	GO:0003887	DNA-directed DNA polymerase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0003677	DNA binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.86	GO:0060388	vitelline envelope
0.43	GO:0005576	extracellular region
0.34	GO:0009360	DNA polymerase III complex
0.33	GO:0005886	plasma membrane
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.34

GO:0003887

sp|P13360|GLAS_DROME
Protein glass
Search

0.11

Glass

0.36	GO:0007601	visual perception
0.36	GO:1904640	response to methionine
0.35	GO:0032026	response to magnesium ion
0.35	GO:1902074	response to salt
0.35	GO:0030182	neuron differentiation
0.35	GO:0010226	response to lithium ion
0.35	GO:0010446	response to alkaline pH
0.35	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:0007635	chemosensory behavior
0.35	GO:0050921	positive regulation of chemotaxis

0.51	GO:0003676	nucleic acid binding
0.34	GO:0005118	sevenless binding
0.34	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.34	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.33	GO:0046872	metal ion binding
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P13368|7LESS_DROME
Protein sevenless
Search

0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.64	GO:0045464	R8 cell fate specification
0.63	GO:0045678	positive regulation of R7 cell differentiation
0.63	GO:0007465	R7 cell fate commitment
0.61	GO:0042067	establishment of ommatidial planar polarity
0.44	GO:0045467	R7 cell development
0.43	GO:0007601	visual perception
0.42	GO:0008595	anterior/posterior axis specification, embryo
0.39	GO:0006357	regulation of transcription by RNA polymerase II

0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0005515	protein binding

0.49	GO:0005887	integral component of plasma membrane
0.33	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0009986	cell surface

0.80

GO:0004714

sp|P13395|SPTCA_DROME
Spectrin alpha chain
Search

0.52	Spectrin alpha chain, non-erythrocytic

0.30	GO:0110053	regulation of actin filament organization
0.30	GO:0040011	locomotion
0.30	GO:0042221	response to chemical
0.30	GO:0051494	negative regulation of cytoskeleton organization
0.30	GO:0007009	plasma membrane organization
0.30	GO:0030182	neuron differentiation
0.30	GO:0031110	regulation of microtubule polymerization or depolymerization
0.30	GO:0097435	supramolecular fiber organization
0.30	GO:0032989	cellular component morphogenesis
0.30	GO:0007274	neuromuscular synaptic transmission

0.70	GO:0005509	calcium ion binding
0.30	GO:0005516	calmodulin binding
0.30	GO:0008017	microtubule binding
0.30	GO:0003779	actin binding

0.30	GO:0071944	cell periphery
0.30	GO:0016020	membrane
0.30	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0012505	endomembrane system
0.30	GO:0031594	neuromuscular junction
0.30	GO:0044422	organelle part
0.30	GO:0099568	cytoplasmic region
0.30	GO:0045169	fusome

sp|P13468|K10_DROME
DNA-binding protein K10
Search

K10

0.93	DNA-binding protein K10

0.77	GO:0019094	pole plasm mRNA localization
0.72	GO:0030707	ovarian follicle cell development
0.48	GO:0009953	dorsal/ventral pattern formation
0.45	GO:0017148	negative regulation of translation
0.42	GO:0008104	protein localization
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0051301	cell division
0.34	GO:0007049	cell cycle
0.34	GO:0035023	regulation of Rho protein signal transduction

0.45	GO:0003677	DNA binding
0.38	GO:0003723	RNA binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0005634	nucleus
0.33	GO:1902494	catalytic complex
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P13469|MODU_DROME
DNA-binding protein modulo
Search

0.95	DNA-binding protein modulo

0.72	GO:0008283	cell proliferation
0.35	GO:0016070	RNA metabolic process
0.35	GO:0010467	gene expression
0.34	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0042254	ribosome biogenesis
0.34	GO:0098507	polynucleotide 5' dephosphorylation
0.34	GO:0032259	methylation
0.34	GO:0051128	regulation of cellular component organization
0.34	GO:0034654	nucleobase-containing compound biosynthetic process
0.34	GO:0009725	response to hormone

0.59	GO:0043565	sequence-specific DNA binding
0.58	GO:0003723	RNA binding
0.41	GO:0005515	protein binding
0.34	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.34	GO:0005509	calcium ion binding
0.34	GO:0004651	polynucleotide 5'-phosphatase activity
0.33	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0003887	DNA-directed DNA polymerase activity
0.33	GO:0016987	bacterial sigma factor activity
0.33	GO:0016757	transferase activity, transferring glycosyl groups

0.66	GO:0005730	nucleolus
0.55	GO:0043234	protein complex
0.46	GO:0005737	cytoplasm
0.34	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
0.30	GO:0016020	membrane

0.34

EC:3.1.3.33

GO:0004651

sp|P13496|DCTN1_DROME
Dynactin subunit 1
Search

0.61	Dynactin subunit

0.81	GO:0010970	transport along microtubule
0.58	GO:0099519	dense core granule cytoskeletal transport
0.57	GO:0061670	evoked neurotransmitter secretion
0.56	GO:0016330	second mitotic wave involved in compound eye morphogenesis
0.55	GO:0051256	mitotic spindle midzone assembly
0.55	GO:0035011	melanotic encapsulation of foreign target
0.55	GO:0042052	rhabdomere development
0.55	GO:0099514	synaptic vesicle cytoskeletal transport
0.55	GO:0045198	establishment of epithelial cell apical/basal polarity
0.54	GO:0007098	centrosome cycle

0.84	GO:0070840	dynein complex binding
0.53	GO:0045505	dynein intermediate chain binding
0.51	GO:0008017	microtubule binding
0.40	GO:0019901	protein kinase binding
0.37	GO:0003774	motor activity
0.33	GO:0042802	identical protein binding
0.32	GO:0003676	nucleic acid binding

0.82	GO:0005869	dynactin complex
0.56	GO:0061176	type Ib terminal bouton
0.54	GO:0031616	spindle pole centrosome
0.54	GO:0005818	aster
0.53	GO:1904115	axon cytoplasm
0.53	GO:0005828	kinetochore microtubule
0.53	GO:0000776	kinetochore
0.52	GO:0030496	midbody
0.43	GO:0035371	microtubule plus-end
0.43	GO:0120103	centriolar subdistal appendage

sp|P13582|EAST_DROME
Serine protease easter
Search

0.44	Fat body serine protease

0.61	GO:0006508	proteolysis
0.49	GO:0007370	ventral furrow formation
0.48	GO:0009950	dorsal/ventral axis specification
0.44	GO:0009620	response to fungus
0.43	GO:0035006	melanization defense response
0.40	GO:0008063	Toll signaling pathway
0.39	GO:0002816	regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria
0.39	GO:0002804	positive regulation of antifungal peptide production
0.39	GO:0045752	positive regulation of Toll signaling pathway
0.39	GO:0006964	positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria

0.69	GO:0004252	serine-type endopeptidase activity
0.35	GO:0098808	mRNA cap binding
0.33	GO:0003743	translation initiation factor activity

0.50	GO:0098595	perivitelline space
0.34	GO:0016282	eukaryotic 43S preinitiation complex
0.34	GO:0033290	eukaryotic 48S preinitiation complex
0.34	GO:0005852	eukaryotic translation initiation factor 3 complex
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P13607|ATNA_DROME
Sodium/potassium-transporting ATPase subunit alpha
Search

0.64	Sodium/potassium-transporting ATPase subunit alpha

0.85	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.76	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.47	GO:0007630	jump response
0.47	GO:0035158	regulation of tube diameter, open tracheal system
0.46	GO:0060439	trachea morphogenesis
0.46	GO:0019991	septate junction assembly
0.46	GO:0051124	synaptic growth at neuromuscular junction
0.45	GO:0001700	embryonic development via the syncytial blastoderm

0.85	GO:0005391	sodium:potassium-exchanging ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0046872	metal ion binding

0.46	GO:0005918	septate junction
0.44	GO:0016323	basolateral plasma membrane
0.38	GO:0005634	nucleus
0.35	GO:0005890	sodium:potassium-exchanging ATPase complex
0.32	GO:0005737	cytoplasm

0.85

EC:3.6.3.9

GO:0005391

sp|P13677|KPC2_DROME
Protein kinase C, eye isozyme
Search

0.87	Protein kinase C, brain isozyme

0.63	GO:0006468	protein phosphorylation
0.61	GO:0035556	intracellular signal transduction
0.55	GO:2000370	positive regulation of clathrin-dependent endocytosis
0.51	GO:0030845	phospholipase C-inhibiting G-protein coupled receptor signaling pathway
0.51	GO:0016062	adaptation of rhodopsin mediated signaling
0.51	GO:0016059	deactivation of rhodopsin mediated signaling
0.49	GO:0050962	detection of light stimulus involved in sensory perception
0.48	GO:0045471	response to ethanol
0.48	GO:0008585	female gonad development
0.46	GO:0016477	cell migration

0.83	GO:0004697	protein kinase C activity
0.62	GO:0008270	zinc ion binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.42	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.35	GO:0035403	histone kinase activity (H3-T6 specific)
0.35	GO:0050681	androgen receptor binding
0.34	GO:0005080	protein kinase C binding

0.50	GO:0016028	rhabdomere
0.45	GO:0005768	endosome
0.35	GO:0019897	extrinsic component of plasma membrane
0.35	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0098797	plasma membrane protein complex
0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.83

EC:2.7.11.13

GO:0004697

sp|P13678|KPC3_DROME
Protein kinase C
Search

PRKCE

0.90	Calcium-independent protein kinase C

0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.54	GO:0045471	response to ethanol
0.51	GO:0007610	behavior
0.50	GO:0035669	TRAM-dependent toll-like receptor 4 signaling pathway
0.50	GO:2001031	positive regulation of cellular glucuronidation
0.49	GO:0002281	macrophage activation involved in immune response
0.49	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.49	GO:0010763	positive regulation of fibroblast migration
0.49	GO:0070257	positive regulation of mucus secretion

0.83	GO:0004697	protein kinase C activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.54	GO:0046872	metal ion binding
0.49	GO:0030546	receptor activator activity
0.49	GO:0071889	14-3-3 protein binding
0.47	GO:0003785	actin monomer binding
0.46	GO:0043178	alcohol binding

0.47	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0005794	Golgi apparatus
0.42	GO:0005783	endoplasmic reticulum
0.42	GO:0005829	cytosol
0.41	GO:0005856	cytoskeleton
0.41	GO:0005634	nucleus
0.40	GO:0005739	mitochondrion
0.39	GO:0005886	plasma membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0031984	organelle subcompartment

0.83

EC:2.7.11.13

GO:0004697

sp|P13706|GPDA_DROME
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
Search

GPDH

0.67	Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

0.79	GO:0046168	glycerol-3-phosphate catabolic process
0.60	GO:0005975	carbohydrate metabolic process
0.53	GO:0055114	oxidation-reduction process
0.48	GO:0007629	flight behavior
0.47	GO:0055093	response to hyperoxia
0.45	GO:0006067	ethanol metabolic process
0.45	GO:0006641	triglyceride metabolic process
0.38	GO:0006650	glycerophospholipid metabolic process

0.79	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity
0.75	GO:0042803	protein homodimerization activity
0.68	GO:0051287	NAD binding

0.76	GO:0009331	glycerol-3-phosphate dehydrogenase complex
0.47	GO:0031430	M band
0.46	GO:0030018	Z disc

0.79	EC:1.1.1.8 EC:1.1.1.94	GO:0004367
0.79	KEGG:R00842	GO:0004367

sp|P13709|FSH_DROME
Homeotic protein female sterile
Search

0.56	Homeotic protein female sterile

0.66	GO:0006413	translational initiation
0.61	GO:0007362	terminal region determination
0.58	GO:0048813	dendrite morphogenesis
0.56	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.51	GO:0045892	negative regulation of transcription, DNA-templated

0.67

GO:0003743

translation initiation factor activity

0.46	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P14003|HAIR_DROME
Protein hairy
Search

0.56	Putative transcriptional repressors of the hairy/espl family

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0007435	salivary gland morphogenesis
0.51	GO:0007424	open tracheal system development
0.50	GO:0001666	response to hypoxia
0.49	GO:0035239	tube morphogenesis
0.48	GO:0048869	cellular developmental process
0.48	GO:0051253	negative regulation of RNA metabolic process

0.68	GO:0046983	protein dimerization activity
0.55	GO:0003677	DNA binding
0.54	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0008134	transcription factor binding
0.36	GO:0042826	histone deacetylase binding
0.34	GO:0051087	chaperone binding
0.34	GO:0042802	identical protein binding
0.32	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|P14083|LOV_DROME
Protein jim lovell
Search

0.47	GO:0008346	larval walking behavior
0.45	GO:0048060	negative gravitaxis
0.44	GO:0030536	larval feeding behavior
0.44	GO:0007418	ventral midline development
0.44	GO:0008049	male courtship behavior
0.42	GO:0048477	oogenesis
0.41	GO:0006357	regulation of transcription by RNA polymerase II
0.32	GO:0006508	proteolysis

0.53	GO:0003677	DNA binding
0.33	GO:0008234	cysteine-type peptidase activity
0.32	GO:0046872	metal ion binding

0.38	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33

GO:0008234

sp|P14199|REF2P_DROME
Protein ref(2)P
Search

0.85	Refractory to sigma P

0.80	GO:0030382	sperm mitochondrion organization
0.44	GO:0006511	ubiquitin-dependent protein catabolic process
0.40	GO:0006351	transcription, DNA-templated
0.34	GO:0006030	chitin metabolic process
0.32	GO:0005975	carbohydrate metabolic process

0.63	GO:0008270	zinc ion binding
0.47	GO:0043130	ubiquitin binding
0.44	GO:0042802	identical protein binding
0.39	GO:0003677	DNA binding
0.34	GO:0008061	chitin binding
0.33	GO:0030246	carbohydrate binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.73	GO:0005776	autophagosome
0.49	GO:0016235	aggresome
0.41	GO:0005634	nucleus
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.33

GO:0004553

sp|P14318|MP20_DROME
Muscle-specific protein 20
Search

0.72	Muscle-specific protein 20

0.71	GO:0031032	actomyosin structure organization
0.63	GO:1901739	regulation of myoblast fusion
0.62	GO:0007520	myoblast fusion
0.35	GO:0005975	carbohydrate metabolic process

0.65	GO:0003779	actin binding
0.45	GO:0005516	calmodulin binding
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.36	GO:0046872	metal ion binding

0.36

GO:0004553

sp|P14484|CUPP_DROME
Pupal cuticle protein
Search

0.72	Larval cuticle protein LCP-14

0.42

GO:0040003

chitin-based cuticle development

0.79

GO:0042302

structural constituent of cuticle

0.40	GO:0031012	extracellular matrix
0.30	GO:0044425	membrane part

sp|P14599|A4_DROME
Beta-amyloid-like protein
Search

0.38	GO:0051602	response to electrical stimulus
0.38	GO:0007614	short-term memory
0.38	GO:0016319	mushroom body development
0.38	GO:0048678	response to axon injury
0.38	GO:0007616	long-term memory
0.37	GO:0007422	peripheral nervous system development
0.37	GO:1901215	negative regulation of neuron death
0.37	GO:0050808	synapse organization
0.37	GO:0048812	neuron projection morphogenesis

0.79	GO:0008201	heparin binding
0.56	GO:0046914	transition metal ion binding
0.35	GO:0005515	protein binding

0.35	GO:0005576	extracellular region
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P14734|FKH_DROME
Protein fork head
Search

0.80	LOW QUALITY PROTEIN: protein fork head

0.57	GO:0006355	regulation of transcription, DNA-templated
0.48	GO:0035072	ecdysone-mediated induction of salivary gland cell autophagic cell death
0.48	GO:0061101	neuroendocrine cell differentiation
0.48	GO:0051093	negative regulation of developmental process
0.47	GO:0051241	negative regulation of multicellular organismal process
0.47	GO:0007443	Malpighian tubule morphogenesis
0.47	GO:0042023	DNA endoreduplication
0.46	GO:1903508	positive regulation of nucleic acid-templated transcription
0.46	GO:0040014	regulation of multicellular organism growth
0.46	GO:0030308	negative regulation of cell growth

0.75	GO:0019904	protein domain specific binding
0.71	GO:0008134	transcription factor binding
0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.46	GO:0005700	polytene chromosome
0.40	GO:0030054	cell junction
0.38	GO:0070013	intracellular organelle lumen
0.36	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm

sp|P14773|HMDH_DROME
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Search

0.56	3-hydroxy-3-methylglutaryl-coenzyme A reductase

0.74	GO:0015936	coenzyme A metabolic process
0.70	GO:0008299	isoprenoid biosynthetic process
0.59	GO:0035232	germ cell attraction
0.57	GO:0007280	pole cell migration
0.56	GO:0018990	ecdysis, chitin-based cuticle
0.54	GO:0035050	embryonic heart tube development
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0007626	locomotory behavior
0.40	GO:0016126	sterol biosynthetic process
0.37	GO:0046579	positive regulation of Ras protein signal transduction

0.82	GO:0004420	hydroxymethylglutaryl-CoA reductase (NADPH) activity
0.69	GO:0050661	NADP binding
0.35	GO:0003839	gamma-glutamylcyclotransferase activity
0.34	GO:0042282	hydroxymethylglutaryl-CoA reductase activity
0.32	GO:0043168	anion binding

0.71	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0031903	microbody membrane
0.40	GO:0044439	peroxisomal part
0.30	GO:0031224	intrinsic component of membrane

0.82	EC:1.1.1.34	GO:0004420
0.82	KEGG:R02082	GO:0004420

sp|P14785|CCNA_DROME
G2/mitotic-specific cyclin-A
Search

0.67	Cyclin A [Nasonia vitripennis]

0.54	GO:0035186	syncytial blastoderm mitotic cell cycle
0.53	GO:0009794	regulation of mitotic cell cycle, embryonic
0.52	GO:0035561	regulation of chromatin binding
0.52	GO:0055059	asymmetric neuroblast division
0.51	GO:1902808	positive regulation of cell cycle G1/S phase transition
0.50	GO:0007096	regulation of exit from mitosis
0.49	GO:0000070	mitotic sister chromatid segregation
0.47	GO:0045859	regulation of protein kinase activity
0.38	GO:0007422	peripheral nervous system development
0.37	GO:0045841	negative regulation of mitotic metaphase/anaphase transition

0.50	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.35	GO:0030246	carbohydrate binding
0.35	GO:0005515	protein binding
0.34	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0030170	pyridoxal phosphate binding
0.33	GO:0022857	transmembrane transporter activity

0.61	GO:0005634	nucleus
0.54	GO:0045170	spectrosome
0.35	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

0.50

GO:0016538

sp|P14954|CECA_DROME
Cecropin-A1/A2
Search

0.96	Sarcotoxin-G

0.85	GO:0019731	antibacterial humoral response
0.77	GO:0045087	innate immune response
0.52	GO:0050830	defense response to Gram-positive bacterium
0.52	GO:0050829	defense response to Gram-negative bacterium
0.38	GO:0019835	cytolysis

0.66	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|P14956|CECB_DROME
Cecropin-B
Search

0.96	Sarcotoxin-G

0.85	GO:0019731	antibacterial humoral response
0.77	GO:0045087	innate immune response
0.52	GO:0050830	defense response to Gram-positive bacterium
0.52	GO:0050829	defense response to Gram-negative bacterium
0.37	GO:0019835	cytolysis

0.66	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|P15007|ENO_DROME
Enolase
Search

0.39

Enolase

0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0046496	nicotinamide nucleotide metabolic process
0.47	GO:0042593	glucose homeostasis

0.78	GO:0004634	phosphopyruvate hydratase activity
0.64	GO:0000287	magnesium ion binding

0.77	GO:0000015	phosphopyruvate hydratase complex
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.78

EC:4.2.1.11

GO:0004634

sp|P15215|LAMC1_DROME
Laminin subunit gamma-1
Search

0.83	Laminin subunit gamma-1

0.75	GO:0061031	endodermal digestive tract morphogenesis
0.74	GO:0070831	basement membrane assembly
0.73	GO:0007494	midgut development
0.73	GO:0033627	cell adhesion mediated by integrin
0.71	GO:0034446	substrate adhesion-dependent cell spreading
0.71	GO:0007435	salivary gland morphogenesis
0.34	GO:0009190	cyclic nucleotide biosynthetic process
0.33	GO:0035556	intracellular signal transduction

0.34	GO:0016849	phosphorus-oxygen lyase activity
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.72	GO:0005605	basal lamina
0.32	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.34

EC:4.6

GO:0016849

sp|P15278|FAS3_DROME
Fasciclin-3
Search

FAS3

0.91	Fasciclin-3

0.39	GO:0016200	synaptic target attraction
0.39	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.38	GO:0007413	axonal fasciculation
0.38	GO:0030707	ovarian follicle cell development
0.38	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.37	GO:0007411	axon guidance

0.38	GO:0050839	cell adhesion molecule binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0005102	receptor binding
0.36	GO:0004872	receptor activity
0.35	GO:0016787	hydrolase activity

0.39	GO:0005920	smooth septate junction
0.38	GO:0005913	cell-cell adherens junction
0.38	GO:0016328	lateral plasma membrane
0.38	GO:0031594	neuromuscular junction
0.37	GO:0055037	recycling endosome
0.37	GO:0016323	basolateral plasma membrane
0.37	GO:0031965	nuclear membrane
0.36	GO:0005887	integral component of plasma membrane
0.36	GO:0005829	cytosol

0.35

GO:0016787

sp|P15330|DORS_DROME
Embryonic polarity protein dorsal
Search

0.76	Embryonic polarity protein dorsal

0.61	GO:0006357	regulation of transcription by RNA polymerase II
0.53	GO:0042387	plasmatocyte differentiation
0.53	GO:0006964	positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria
0.52	GO:0035206	regulation of hemocyte proliferation
0.52	GO:0035006	melanization defense response
0.51	GO:0048935	peripheral nervous system neuron development
0.47	GO:0006366	transcription by RNA polymerase II
0.46	GO:0045893	positive regulation of transcription, DNA-templated
0.44	GO:0010629	negative regulation of gene expression
0.42	GO:0001715	ectodermal cell fate specification

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0070379	high mobility group box 1 binding
0.55	GO:0003677	DNA binding
0.50	GO:0070491	repressing transcription factor binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0042802	identical protein binding
0.39	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.53	GO:0071212	subsynaptic reticulum
0.50	GO:0031594	neuromuscular junction
0.42	GO:0033256	I-kappaB/NF-kappaB complex
0.37	GO:0005829	cytosol
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part

sp|P15348|TOP2_DROME
DNA topoisomerase 2
Search

0.64	DNA topoisomerase 2-beta

0.72	GO:0006265	DNA topological change
0.51	GO:0007060	male meiosis chromosome segregation
0.49	GO:0000819	sister chromatid segregation
0.49	GO:0051310	metaphase plate congression
0.49	GO:1903047	mitotic cell cycle process
0.48	GO:0006342	chromatin silencing
0.47	GO:0030261	chromosome condensation
0.44	GO:0000712	resolution of meiotic recombination intermediates
0.42	GO:0031570	DNA integrity checkpoint
0.42	GO:0048513	animal organ development

0.74	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity
0.55	GO:0030554	adenyl nucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0003682	chromatin binding
0.46	GO:0003729	mRNA binding
0.40	GO:0005080	protein kinase C binding
0.39	GO:0042826	histone deacetylase binding

0.51	GO:0008623	CHRAC
0.47	GO:0000793	condensed chromosome
0.38	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)
0.37	GO:0005654	nucleoplasm
0.37	GO:0016590	ACF complex
0.37	GO:0005814	centriole
0.37	GO:0000792	heterochromatin
0.36	GO:0005730	nucleolus
0.35	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0005829	cytosol

0.74

EC:5.99.1.3

GO:0003918

sp|P15357|RS27A_DROME
Ubiquitin-40S ribosomal protein S27a
Search

RPS27A

0.63	Ubiquitin ribosomal fusion protein S27

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.34	GO:0007623	circadian rhythm
0.33	GO:0036211	protein modification process

0.64	GO:0003735	structural constituent of ribosome
0.35	GO:0046872	metal ion binding
0.34	GO:0031386	protein tag

0.61	GO:0005840	ribosome
0.42	GO:0043209	myelin sheath
0.42	GO:0044445	cytosolic part
0.38	GO:0044446	intracellular organelle part
0.36	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen

sp|P15364|AMAL_DROME
Protein amalgam
Search

0.48	GO:0019991	septate junction assembly
0.42	GO:0010951	negative regulation of endopeptidase activity
0.41	GO:0006508	proteolysis
0.35	GO:0030198	extracellular matrix organization
0.34	GO:0006030	chitin metabolic process

0.42	GO:0004867	serine-type endopeptidase inhibitor activity
0.41	GO:0008233	peptidase activity
0.35	GO:0005201	extracellular matrix structural constituent
0.34	GO:0005509	calcium ion binding
0.34	GO:0008061	chitin binding

0.54	GO:0005886	plasma membrane
0.48	GO:0005918	septate junction
0.45	GO:0031225	anchored component of membrane
0.39	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.41

GO:0008233

sp|P15370|EGON_DROME
Protein embryonic gonad
Search

0.81	Eagle, isoform C

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:0007417	central nervous system development
0.41	GO:0007088	regulation of mitotic nuclear division
0.39	GO:1902679	negative regulation of RNA biosynthetic process
0.36	GO:0030154	cell differentiation
0.34	GO:0007427	epithelial cell migration, open tracheal system
0.34	GO:0035151	regulation of tube size, open tracheal system

0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P15372|ARRA_DROME
Phosrestin-2
Search

ARR1

0.70	Phosrestin ii

0.61	GO:0007165	signal transduction
0.50	GO:0016060	metarhodopsin inactivation
0.50	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin
0.47	GO:0045494	photoreceptor cell maintenance
0.44	GO:0007608	sensory perception of smell
0.43	GO:0006897	endocytosis
0.38	GO:1900136	regulation of chemokine activity
0.37	GO:0001919	regulation of receptor recycling
0.36	GO:0007601	visual perception
0.34	GO:0043086	negative regulation of catalytic activity

0.36	GO:0002046	opsin binding
0.35	GO:0008073	ornithine decarboxylase inhibitor activity
0.32	GO:0016301	kinase activity

0.48	GO:0016028	rhabdomere
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P15425|CYPR_DROME
Peptidyl-prolyl cis-trans isomerase, rhodopsin-specific isozyme
Search

0.46	Peptidyl-prolyl cis-trans isomerase, rhodopsin-specific isozyme

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.67	GO:0006457	protein folding
0.52	GO:0016063	rhodopsin biosynthetic process
0.51	GO:0007603	phototransduction, visible light
0.50	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.50	GO:0006517	protein deglycosylation
0.49	GO:0006491	N-glycan processing
0.38	GO:0007601	visual perception
0.34	GO:0006508	proteolysis

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.52	GO:0016018	cyclosporin A binding
0.35	GO:0004252	serine-type endopeptidase activity

0.49	GO:0005788	endoplasmic reticulum lumen
0.45	GO:0031410	cytoplasmic vesicle
0.37	GO:0016028	rhabdomere
0.36	GO:0031965	nuclear membrane
0.30	GO:0031224	intrinsic component of membrane

0.72

EC:5.2.1.8

GO:0003755

sp|P15619|SRYC_DROME
Serendipity locus protein H-1
Search

0.38	GO:0007275	multicellular organism development
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0097659	nucleic acid-templated transcription
0.36	GO:0010468	regulation of gene expression
0.35	GO:0010467	gene expression
0.35	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.36	GO:0046872	metal ion binding
0.32	GO:0003700	DNA binding transcription factor activity

0.49	GO:0005634	nucleus
0.33	GO:0019013	viral nucleocapsid
0.32	GO:0030529	intracellular ribonucleoprotein complex

sp|P16163|URIC_DROME
Uricase
Search

0.52

Uricase

0.79	GO:0019628	urate catabolic process
0.74	GO:0006144	purine nucleobase metabolic process
0.52	GO:0055114	oxidation-reduction process
0.52	GO:0045471	response to ethanol
0.38	GO:0019428	allantoin biosynthetic process
0.37	GO:0007031	peroxisome organization
0.34	GO:0009877	nodulation

0.85	GO:0004846	urate oxidase activity
0.32	GO:0008270	zinc ion binding

0.70

GO:0042579

microbody

0.85

EC:1.7.3.3

GO:0004846

sp|P16241|CF1A_DROME
POU domain protein CF1A
Search

0.57	POU domain, class 3, transcription factor 3-A

0.64	GO:0007420	brain development
0.58	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.37	GO:0007425	epithelial cell fate determination, open tracheal system
0.37	GO:0035283	central nervous system segmentation
0.37	GO:0002807	positive regulation of antimicrobial peptide biosynthetic process
0.36	GO:0008045	motor neuron axon guidance
0.36	GO:0048814	regulation of dendrite morphogenesis
0.36	GO:0048813	dendrite morphogenesis
0.36	GO:0007422	peripheral nervous system development

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.36	GO:0035326	enhancer binding
0.35	GO:0001012	RNA polymerase II regulatory region DNA binding
0.35	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P16371|GROU_DROME
Protein groucho
Search

GRO

0.94	Groucho protein (Enhancer of split)

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.43	GO:0045879	negative regulation of smoothened signaling pathway
0.43	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.40	GO:0007399	nervous system development
0.40	GO:1902679	negative regulation of RNA biosynthetic process
0.37	GO:0007541	sex determination, primary response to X:A ratio
0.35	GO:0016055	Wnt signaling pathway
0.34	GO:0030154	cell differentiation

0.46	GO:0071906	CRD domain binding
0.44	GO:0071837	HMG box domain binding
0.43	GO:0001106	RNA polymerase II transcription corepressor activity
0.43	GO:0070491	repressing transcription factor binding
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding
0.33	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.37	GO:0043234	protein complex
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.33

GO:0016705

sp|P16376|7UP2_DROME
Steroid receptor seven-up, isoform A
Search

0.85	Steroid receptor seven-up, isoform A

0.80	GO:0030522	intracellular receptor signaling pathway
0.79	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0007510	cardioblast cell fate determination
0.49	GO:0050673	epithelial cell proliferation
0.49	GO:0014019	neuroblast development
0.49	GO:0042331	phototaxis

0.82	GO:0004879	nuclear receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.61	GO:0043565	sequence-specific DNA binding
0.60	GO:0008270	zinc ion binding
0.50	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0042803	protein homodimerization activity
0.44	GO:0046982	protein heterodimerization activity
0.40	GO:0001012	RNA polymerase II regulatory region DNA binding
0.39	GO:0001972	retinoic acid binding
0.39	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.40	GO:0005829	cytosol
0.40	GO:0070013	intracellular organelle lumen
0.37	GO:0044446	intracellular organelle part

sp|P16378|GNAO_DROME
G protein alpha o subunit
Search

0.63	GTP binding protein alpha subunit Go

0.82	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.48	GO:0014045	establishment of endothelial blood-brain barrier
0.48	GO:0042595	behavioral response to starvation
0.47	GO:0060857	establishment of glial blood-brain barrier
0.47	GO:0061343	cell adhesion involved in heart morphogenesis
0.47	GO:0001737	establishment of imaginal disc-derived wing hair orientation
0.47	GO:0019991	septate junction assembly
0.47	GO:0007419	ventral cord development
0.47	GO:0032291	axon ensheathment in central nervous system
0.47	GO:0045886	negative regulation of synaptic growth at neuromuscular junction

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0043495	protein membrane anchor
0.38	GO:0001664	G-protein coupled receptor binding
0.37	GO:0019901	protein kinase binding

0.46	GO:1905360	GTPase complex
0.45	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.41	GO:0098797	plasma membrane protein complex
0.37	GO:0005938	cell cortex
0.30	GO:0031224	intrinsic component of membrane

sp|P16395|ACM1_DROME
Muscarinic acetylcholine receptor DM1
Search

0.81	Muscarinic acetylcholine receptor DM1

0.84	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.59	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.42	GO:0007271	synaptic transmission, cholinergic
0.41	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.35	GO:0046541	saliva secretion
0.34	GO:0050890	cognition
0.34	GO:0040012	regulation of locomotion

0.84

GO:0016907

G-protein coupled acetylcholine receptor activity

0.66	GO:0005887	integral component of plasma membrane
0.39	GO:0045202	synapse
0.39	GO:0098590	plasma membrane region
0.38	GO:0030054	cell junction

sp|P16548|A95EF_DROME
Accessory gland-specific peptide 95EF
Search

0.26	Accessory gland-specific peptide 95EF

0.79	GO:0007610	behavior
0.77	GO:0032504	multicellular organism reproduction
0.75	GO:0010469	regulation of receptor activity

0.79

GO:0005179

hormone activity

0.73

GO:0005615

extracellular space

sp|P16554|NUMB_DROME
Protein numb
Search

0.96	Putative adaptor protein numb

0.85	GO:0045035	sensory organ precursor cell division
0.85	GO:0061320	pericardial nephrocyte differentiation
0.85	GO:0061382	Malpighian tubule tip cell differentiation
0.85	GO:0042694	muscle cell fate specification
0.85	GO:0014019	neuroblast development
0.85	GO:0016360	sensory organ precursor cell fate determination
0.85	GO:0009786	regulation of asymmetric cell division
0.84	GO:0007406	negative regulation of neuroblast proliferation
0.83	GO:0055059	asymmetric neuroblast division
0.82	GO:0051642	centrosome localization

0.44	GO:0005112	Notch binding
0.38	GO:0003924	GTPase activity
0.38	GO:0032555	purine ribonucleotide binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0032550	purine ribonucleoside binding
0.37	GO:0019001	guanyl nucleotide binding
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0008144	drug binding

0.71	GO:0005938	cell cortex
0.43	GO:0045178	basal part of cell
0.38	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P16568|BICD_DROME
Protein bicaudal D
Search

BICD

0.90	Microtubule-associated protein Bicaudal-D

0.38	GO:2000302	positive regulation of synaptic vesicle exocytosis
0.37	GO:0007312	oocyte nucleus migration involved in oocyte dorsal/ventral axis specification
0.37	GO:2000370	positive regulation of clathrin-dependent endocytosis
0.37	GO:0008103	oocyte microtubule cytoskeleton polarization
0.37	GO:0007294	germarium-derived oocyte fate determination
0.37	GO:0048488	synaptic vesicle endocytosis
0.36	GO:0008298	intracellular mRNA localization
0.36	GO:0072385	minus-end-directed organelle transport along microtubule
0.36	GO:0000042	protein targeting to Golgi
0.36	GO:0051028	mRNA transport

0.85	GO:0008093	cytoskeletal adaptor activity
0.84	GO:0070840	dynein complex binding
0.37	GO:0017137	Rab GTPase binding
0.37	GO:0032050	clathrin heavy chain binding
0.36	GO:0034452	dynactin binding
0.35	GO:0051959	dynein light intermediate chain binding
0.35	GO:0003729	mRNA binding

0.36	GO:0030669	clathrin-coated endocytic vesicle membrane
0.36	GO:0005642	annulate lamellae
0.36	GO:0005856	cytoskeleton
0.36	GO:0005829	cytosol
0.35	GO:0045202	synapse
0.35	GO:0005643	nuclear pore
0.34	GO:0005794	Golgi apparatus
0.33	GO:0005886	plasma membrane
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

sp|P16620|PTP69_DROME
Tyrosine-protein phosphatase 69D
Search

0.88	Receptor-type tyrosine-protein phosphatase alpha, putative

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.56	GO:0097155	fasciculation of sensory neuron axon
0.56	GO:0007415	defasciculation of motor neuron axon
0.53	GO:0008045	motor neuron axon guidance
0.53	GO:0048813	dendrite morphogenesis
0.36	GO:0007155	cell adhesion
0.33	GO:0006468	protein phosphorylation
0.33	GO:0050852	T cell receptor signaling pathway
0.32	GO:0018212	peptidyl-tyrosine modification
0.31	GO:0032259	methylation

0.75	GO:0004725	protein tyrosine phosphatase activity
0.55	GO:0019198	transmembrane receptor protein phosphatase activity
0.36	GO:0050254	rhodopsin kinase activity
0.32	GO:0004713	protein tyrosine kinase activity
0.32	GO:0030246	carbohydrate binding
0.31	GO:0008168	methyltransferase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0003676	nucleic acid binding

0.51	GO:0030424	axon
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.75

GO:0004725

sp|P16621|LAR_DROME
Tyrosine-protein phosphatase Lar
Search

LOC108737100

0.74	Receptor-type tyrosine-protein phosphatase F

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.35	GO:0006468	protein phosphorylation
0.30	GO:0048869	cellular developmental process
0.30	GO:0051270	regulation of cellular component movement
0.30	GO:0001654	eye development
0.30	GO:0040011	locomotion
0.30	GO:0040012	regulation of locomotion
0.30	GO:0031346	positive regulation of cell projection organization
0.30	GO:0042221	response to chemical
0.30	GO:0010769	regulation of cell morphogenesis involved in differentiation

0.75	GO:0004725	protein tyrosine phosphatase activity
0.38	GO:0050254	rhodopsin kinase activity
0.30	GO:0099600	transmembrane receptor activity
0.30	GO:0005515	protein binding
0.30	GO:0097367	carbohydrate derivative binding
0.30	GO:0004871	signal transducer activity
0.30	GO:0043167	ion binding
0.30	GO:1901681	sulfur compound binding

0.30	GO:0016020	membrane
0.30	GO:0044464	cell part
0.30	GO:0070161	anchoring junction
0.30	GO:0030055	cell-substrate junction

0.75

GO:0004725

sp|P16905|KAPR1_DROME
cAMP-dependent protein kinase type I regulatory subunit
Search

0.42	cAMP-dependent protein kinase type I regulatory subunit

0.75	GO:0045859	regulation of protein kinase activity
0.52	GO:0016310	phosphorylation
0.46	GO:0036211	protein modification process
0.44	GO:0044267	cellular protein metabolic process
0.36	GO:0008103	oocyte microtubule cytoskeleton polarization
0.35	GO:2000253	positive regulation of feeding behavior
0.35	GO:0008355	olfactory learning
0.35	GO:0007419	ventral cord development
0.35	GO:0007591	molting cycle, chitin-based cuticle
0.35	GO:0007274	neuromuscular synaptic transmission

0.85	GO:0008603	cAMP-dependent protein kinase regulator activity
0.83	GO:0030552	cAMP binding
0.60	GO:0004691	cAMP-dependent protein kinase activity
0.33	GO:0004715	non-membrane spanning protein tyrosine kinase activity

0.84

GO:0005952

cAMP-dependent protein kinase complex

0.60

EC:2.7.11.11

GO:0004691

sp|P16909|18C_DROME
Histone-like protein 18C
Search

0.86	GO:0035092	sperm chromatin condensation
0.78	GO:0043486	histone exchange

0.72	GO:0000785	chromatin
0.56	GO:0036126	sperm flagellum
0.51	GO:0044454	nuclear chromosome part

sp|P16911|KDC1_DROME
Protein kinase DC1
Search

PRKX

0.52	cAMP-dependent protein kinase catalytic subunit alpha

0.63	GO:0006468	protein phosphorylation
0.44	GO:0001935	endothelial cell proliferation
0.44	GO:2000696	regulation of epithelial cell differentiation involved in kidney development
0.43	GO:0018209	peptidyl-serine modification
0.43	GO:0043542	endothelial cell migration
0.43	GO:0060993	kidney morphogenesis
0.42	GO:0001525	angiogenesis
0.42	GO:0030099	myeloid cell differentiation
0.42	GO:0031589	cell-substrate adhesion
0.42	GO:0060562	epithelial tube morphogenesis

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0060089	molecular transducer activity
0.36	GO:0034237	protein kinase A regulatory subunit binding
0.34	GO:0030553	cGMP binding
0.33	GO:0016307	phosphatidylinositol phosphate kinase activity
0.33	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0003774	motor activity

0.38	GO:0005634	nucleus
0.36	GO:0031588	nucleotide-activated protein kinase complex
0.36	GO:0005952	cAMP-dependent protein kinase complex
0.35	GO:0005737	cytoplasm
0.35	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.33	GO:0016459	myosin complex
0.30	GO:0016021	integral component of membrane

0.69

GO:0004674

sp|P16912|KDC2_DROME
Protein kinase DC2
Search

0.55	Putative camp-dependent protein kinase catalytic subunit

0.63	GO:0006468	protein phosphorylation
0.49	GO:0060562	epithelial tube morphogenesis
0.48	GO:0035120	post-embryonic appendage morphogenesis
0.48	GO:0035114	imaginal disc-derived appendage morphogenesis
0.48	GO:0035220	wing disc development
0.48	GO:0048563	post-embryonic animal organ morphogenesis
0.48	GO:0048707	instar larval or pupal morphogenesis
0.48	GO:0007552	metamorphosis
0.40	GO:2000696	regulation of epithelial cell differentiation involved in kidney development
0.40	GO:0001935	endothelial cell proliferation

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0060089	molecular transducer activity
0.34	GO:0005515	protein binding

0.36	GO:0005952	cAMP-dependent protein kinase complex
0.35	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.69

GO:0004674

sp|P16914|ELAV_DROME
Protein elav
Search

ELAV

0.26	Embryonic lethal abnormal vision

0.49	GO:0031441	negative regulation of mRNA 3'-end processing
0.45	GO:0048856	anatomical structure development
0.45	GO:0036093	germ cell proliferation
0.43	GO:0022412	cellular process involved in reproduction in multicellular organism
0.42	GO:0007292	female gamete generation
0.42	GO:0003006	developmental process involved in reproduction
0.41	GO:0030154	cell differentiation
0.37	GO:0007319	negative regulation of oskar mRNA translation

0.59	GO:0003723	RNA binding
0.36	GO:0000900	translation repressor activity, nucleic acid binding

0.48	GO:0015030	Cajal body
0.30	GO:0031224	intrinsic component of membrane

sp|P17133|RU17_DROME
U1 small nuclear ribonucleoprotein 70 kDa
Search

0.82	U1 small nuclear ribonucleoprotein 70 kDa

0.43	GO:0048024	regulation of mRNA splicing, via spliceosome
0.43	GO:0060218	hematopoietic stem cell differentiation
0.42	GO:0033119	negative regulation of RNA splicing
0.41	GO:0048477	oogenesis
0.40	GO:0007283	spermatogenesis
0.40	GO:0000398	mRNA splicing, via spliceosome
0.40	GO:0050686	negative regulation of mRNA processing
0.37	GO:0050685	positive regulation of mRNA processing
0.37	GO:0033120	positive regulation of RNA splicing
0.34	GO:0071300	cellular response to retinoic acid

0.83	GO:0030619	U1 snRNA binding
0.43	GO:0003729	mRNA binding
0.35	GO:1990446	U1 snRNP binding
0.31	GO:0005515	protein binding

0.59	GO:0019013	viral nucleocapsid
0.52	GO:0030529	intracellular ribonucleoprotein complex
0.41	GO:0120114	Sm-like protein family complex
0.38	GO:0044428	nuclear part
0.35	GO:0031974	membrane-enclosed lumen
0.32	GO:0005737	cytoplasm
0.31	GO:1902494	catalytic complex
0.30	GO:0016020	membrane

sp|P17205|SER1_DROME
Serine proteases 1/2
Search

0.79	Serine protease 1

0.61

GO:0006508

proteolysis

0.69

GO:0004252

serine-type endopeptidase activity

0.32	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004252

sp|P17207|SER3_DROME
Serine protease 3
Search

0.76	Serine protease 3

0.61	GO:0006508	proteolysis
0.37	GO:0006898	receptor-mediated endocytosis
0.34	GO:0007596	blood coagulation
0.33	GO:0007586	digestion
0.33	GO:0006429	leucyl-tRNA aminoacylation
0.32	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity

0.69	GO:0004252	serine-type endopeptidase activity
0.38	GO:0005044	scavenger receptor activity
0.33	GO:0008234	cysteine-type peptidase activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0004823	leucine-tRNA ligase activity
0.32	GO:0002161	aminoacyl-tRNA editing activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.33	GO:0005576	extracellular region
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.69	EC:3.4.21	GO:0004252
0.33	KEGG:R03657	GO:0004823

sp|P17210|KINH_DROME
Kinesin heavy chain
Search

0.51	Kinesin heavy chain

0.74	GO:0007018	microtubule-based movement
0.48	GO:0035617	stress granule disassembly
0.48	GO:0008103	oocyte microtubule cytoskeleton polarization
0.48	GO:0007317	regulation of pole plasm oskar mRNA localization
0.48	GO:0045451	pole plasm oskar mRNA localization
0.47	GO:0008345	larval locomotory behavior
0.47	GO:0007310	oocyte dorsal/ventral axis specification
0.47	GO:0046843	dorsal appendage formation
0.47	GO:0051299	centrosome separation
0.47	GO:0007097	nuclear migration

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0005523	tropomyosin binding
0.42	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.32	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.69	GO:0005874	microtubule
0.48	GO:0030478	actin cap
0.47	GO:0032839	dendrite cytoplasm
0.46	GO:0005871	kinesin complex
0.46	GO:1904115	axon cytoplasm
0.46	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)
0.44	GO:0045202	synapse
0.34	GO:0005635	nuclear envelope
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|P17276|PH4H_DROME
Protein henna
Search

0.49	Biopterin-dependent aromatic amino acid hydroxylase

0.77	GO:0006559	L-phenylalanine catabolic process
0.53	GO:0055114	oxidation-reduction process
0.48	GO:0006726	eye pigment biosynthetic process
0.47	GO:0007616	long-term memory
0.39	GO:0071391	cellular response to estrogen stimulus
0.36	GO:0042427	serotonin biosynthetic process
0.33	GO:0006508	proteolysis

0.83	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
0.63	GO:0005506	iron ion binding
0.35	GO:0018683	camphor 5-monooxygenase activity
0.33	GO:0004252	serine-type endopeptidase activity

0.30

GO:0016020

membrane

0.83

EC:1.14.16

GO:0016714

sp|P17336|CATA_DROME
Catalase
Search

0.53

Catalase

0.76	GO:0042744	hydrogen peroxide catabolic process
0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.53	GO:0055114	oxidation-reduction process
0.47	GO:0038001	paracrine signaling
0.47	GO:1901700	response to oxygen-containing compound
0.47	GO:0036335	intestinal stem cell homeostasis
0.47	GO:0035206	regulation of hemocyte proliferation
0.45	GO:0009650	UV protection
0.45	GO:0020027	hemoglobin metabolic process

0.77	GO:0004096	catalase activity
0.63	GO:0020037	heme binding
0.53	GO:0046872	metal ion binding
0.44	GO:0004046	aminoacylase activity
0.41	GO:0042803	protein homodimerization activity
0.40	GO:0005102	receptor binding
0.40	GO:0019899	enzyme binding
0.40	GO:0050661	NADP binding

0.44	GO:0005777	peroxisome
0.42	GO:0031903	microbody membrane
0.39	GO:0005739	mitochondrion
0.34	GO:0031970	organelle envelope lumen
0.34	GO:0005764	lysosome
0.33	GO:0005615	extracellular space
0.33	GO:0005794	Golgi apparatus
0.33	GO:0005783	endoplasmic reticulum
0.33	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane

0.77

EC:1.11.1.6

GO:0004096

sp|P17644|ACH2_DROME
Acetylcholine receptor subunit alpha-like 2
Search

0.83	Acetylcholine receptor subunit alpha

0.76	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.49	GO:0007271	synaptic transmission, cholinergic
0.40	GO:0006812	cation transport
0.35	GO:0017085	response to insecticide
0.33	GO:0006508	proteolysis

0.79	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.33	GO:0004252	serine-type endopeptidase activity

0.76	GO:0045211	postsynaptic membrane
0.70	GO:0030054	cell junction
0.49	GO:0005892	acetylcholine-gated channel complex

0.33

GO:0004252

sp|P17704|RS17_DROME
40S ribosomal protein S17
Search

RPS17

0.65	Ribosomal protein S17

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.40	GO:0000028	ribosomal small subunit assembly
0.34	GO:0007062	sister chromatid cohesion
0.34	GO:0000724	double-strand break repair via homologous recombination
0.33	GO:0006631	fatty acid metabolic process
0.32	GO:0055114	oxidation-reduction process

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity

0.61	GO:0005840	ribosome
0.38	GO:0044445	cytosolic part
0.35	GO:0044446	intracellular organelle part
0.34	GO:0106068	SUMO ligase complex
0.34	GO:0000793	condensed chromosome
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:1.1.1.35

GO:0003857

sp|P17719|DYR_DROME
Dihydrofolate reductase
Search

0.40	Dihydrofolate reductase

0.75	GO:0046654	tetrahydrofolate biosynthetic process
0.74	GO:0006545	glycine biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.46	GO:0006730	one-carbon metabolic process
0.41	GO:0006231	dTMP biosynthetic process
0.38	GO:0032259	methylation
0.37	GO:0046452	dihydrofolate metabolic process
0.35	GO:0006260	DNA replication
0.35	GO:0016310	phosphorylation
0.33	GO:0000027	ribosomal large subunit assembly

0.79	GO:0004146	dihydrofolate reductase activity
0.68	GO:0050661	NADP binding
0.42	GO:0004799	thymidylate synthase activity
0.36	GO:0003729	mRNA binding
0.35	GO:0016301	kinase activity
0.34	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0031981	nuclear lumen
0.32	GO:0044444	cytoplasmic part
0.30	GO:0016020	membrane

0.79	EC:1.5.1.3	GO:0004146
0.42	KEGG:R02101	GO:0004799

sp|P17886|CRN_DROME
Protein crooked neck
Search

0.58	Fatty alcohol acetyltransferase

0.63	GO:0006396	RNA processing
0.48	GO:0007438	oenocyte development
0.47	GO:0007443	Malpighian tubule morphogenesis
0.47	GO:0022618	ribonucleoprotein complex assembly
0.46	GO:0008347	glial cell migration
0.46	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.45	GO:0008366	axon ensheathment
0.45	GO:0016071	mRNA metabolic process

0.40	GO:0003723	RNA binding
0.34	GO:0016740	transferase activity
0.33	GO:0005515	protein binding

0.50	GO:0071013	catalytic step 2 spliceosome
0.48	GO:0005684	U2-type spliceosomal complex
0.45	GO:0016607	nuclear speck
0.44	GO:0071012	catalytic step 1 spliceosome
0.44	GO:0071011	precatalytic spliceosome
0.44	GO:0000974	Prp19 complex
0.43	GO:0071010	prespliceosome
0.43	GO:0071014	post-mRNA release spliceosomal complex
0.36	GO:0005737	cytoplasm

0.34

GO:0016740

sp|P17917|PCNA_DROME
Proliferating cell nuclear antigen
Search

0.66	Proliferating cell nuclear antigen

0.77	GO:0006275	regulation of DNA replication
0.66	GO:0006260	DNA replication
0.48	GO:0019985	translesion synthesis
0.47	GO:0032077	positive regulation of deoxyribonuclease activity
0.46	GO:0045739	positive regulation of DNA repair
0.46	GO:0019730	antimicrobial humoral response
0.46	GO:0034644	cellular response to UV
0.45	GO:0007052	mitotic spindle organization
0.45	GO:0030855	epithelial cell differentiation
0.45	GO:0006298	mismatch repair

0.84	GO:0030337	DNA polymerase processivity factor activity
0.55	GO:0003677	DNA binding
0.49	GO:0000701	purine-specific mismatch base pair DNA N-glycosylase activity
0.48	GO:0032405	MutLalpha complex binding
0.47	GO:0070182	DNA polymerase binding
0.47	GO:0035035	histone acetyltransferase binding
0.46	GO:0030971	receptor tyrosine kinase binding
0.44	GO:0003682	chromatin binding
0.43	GO:0042802	identical protein binding
0.34	GO:0030331	estrogen receptor binding

0.61	GO:0005634	nucleus
0.49	GO:0043626	PCNA complex
0.44	GO:0005813	centrosome
0.43	GO:0005657	replication fork
0.41	GO:0070013	intracellular organelle lumen
0.34	GO:0070062	extracellular exosome
0.34	GO:0000781	chromosome, telomeric region
0.33	GO:0032993	protein-DNA complex
0.30	GO:0016020	membrane

0.49

EC:3.2.2

GO:0000701

sp|P17970|KCNAB_DROME
Potassium voltage-gated channel protein Shab
Search

0.84	Potassium voltage-gated channel protein Shab

0.75	GO:0051260	protein homooligomerization
0.74	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.38	GO:0060025	regulation of synaptic activity
0.38	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep
0.38	GO:0008345	larval locomotory behavior
0.37	GO:0001508	action potential
0.37	GO:0008016	regulation of heart contraction
0.36	GO:0007268	chemical synaptic transmission

0.78

GO:0005249

voltage-gated potassium channel activity

0.78

GO:0008076

voltage-gated potassium channel complex

sp|P17971|KCNAL_DROME
Potassium voltage-gated channel protein Shal
Search

0.52	Potassium voltage-gated channel protein Shal

0.77	GO:0051260	protein homooligomerization
0.77	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.46	GO:0008306	associative learning
0.44	GO:0007268	chemical synaptic transmission
0.34	GO:0019228	neuronal action potential
0.34	GO:0045475	locomotor rhythm
0.34	GO:0019233	sensory perception of pain

0.78

GO:0005249

voltage-gated potassium channel activity

0.78	GO:0008076	voltage-gated potassium channel complex
0.36	GO:0043025	neuronal cell body
0.36	GO:0030425	dendrite
0.34	GO:0044309	neuron spine
0.34	GO:0045211	postsynaptic membrane

sp|P17972|KCNAW_DROME
Potassium voltage-gated channel protein Shaw
Search

0.47	Potassium voltage-gated channel protein Shaw

0.75	GO:0051260	protein homooligomerization
0.75	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.35	GO:0030431	sleep
0.34	GO:0006379	mRNA cleavage
0.32	GO:0006351	transcription, DNA-templated

0.78	GO:0005249	voltage-gated potassium channel activity
0.34	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.78

GO:0008076

voltage-gated potassium channel complex

0.34

EC:3.1.4.17

GO:0004114

sp|P18053|PSA4_DROME
Proteasome subunit alpha type-4
Search

0.47	Proteasome subunit alpha type

0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.35	GO:0010498	proteasomal protein catabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.34	GO:0070498	interleukin-1-mediated signaling pathway

0.77	GO:0070003	threonine-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.34	GO:0005515	protein binding
0.33	GO:0008234	cysteine-type peptidase activity
0.32	GO:0003676	nucleic acid binding
0.32	GO:0016301	kinase activity

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.40	GO:0035770	ribonucleoprotein granule
0.35	GO:0070062	extracellular exosome
0.34	GO:0043233	organelle lumen
0.34	GO:0099023	tethering complex
0.33	GO:0044446	intracellular organelle part
0.32	GO:0071944	cell periphery
0.30	GO:0016021	integral component of membrane

0.33

GO:0008234

sp|P18091|ACTN_DROME
Alpha-actinin, sarcomeric
Search

ACTN

0.79	Alpha-actinin sarcomeric

0.36	GO:0051017	actin filament bundle assembly
0.35	GO:0045214	sarcomere organization
0.35	GO:0007016	cytoskeletal anchoring at plasma membrane
0.35	GO:0035335	peptidyl-tyrosine dephosphorylation
0.35	GO:0051764	actin crosslink formation
0.35	GO:0031532	actin cytoskeleton reorganization
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:0043666	regulation of phosphoprotein phosphatase activity

0.72	GO:0003779	actin binding
0.70	GO:0005509	calcium ion binding
0.36	GO:0032403	protein complex binding
0.35	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0004930	G-protein coupled receptor activity
0.32	GO:0019888	protein phosphatase regulator activity

0.35	GO:0030018	Z disc
0.35	GO:0005925	focal adhesion
0.32	GO:0000159	protein phosphatase type 2A complex
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0004725

sp|P18101|RL40_DROME
Ubiquitin-60S ribosomal protein L40
Search

0.64	Anopheles stephensi ubiquitin

0.60	GO:0006518	peptide metabolic process
0.59	GO:0043604	amide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:1901566	organonitrogen compound biosynthetic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.38	GO:0017085	response to insecticide
0.36	GO:0007623	circadian rhythm
0.35	GO:0035635	entry of bacterium into host cell
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0031386	protein tag
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.46	GO:0005829	cytosol
0.43	GO:0005783	endoplasmic reticulum
0.43	GO:0005654	nucleoplasm
0.38	GO:0005886	plasma membrane
0.37	GO:0005765	lysosomal membrane
0.36	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0030666	endocytic vesicle membrane

sp|P18102|TLL_DROME
Protein tailless
Search

TLL

0.60	Nuclear receptor

0.77	GO:0043401	steroid hormone mediated signaling pathway
0.61	GO:0035271	ring gland development
0.60	GO:0001748	optic lobe placode development
0.59	GO:0002121	inter-male aggressive behavior
0.59	GO:0014019	neuroblast development
0.59	GO:0007362	terminal region determination
0.59	GO:0008293	torso signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0055057	neuroblast division
0.57	GO:0016319	mushroom body development

0.77	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.37	GO:0004824	lysine-tRNA ligase activity
0.35	GO:0001012	RNA polymerase II regulatory region DNA binding
0.35	GO:0005515	protein binding
0.35	GO:0003690	double-stranded DNA binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding

0.61	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.37

EC:6.1.1.6

GO:0004824

sp|P18105|NOD_DROME
Kinesin-like protein Nod
Search

0.91	Kinesin-like protein Nod

0.74	GO:0007018	microtubule-based movement
0.53	GO:0051296	establishment of meiotic spindle orientation
0.53	GO:0032837	distributive segregation
0.53	GO:0007057	spindle assembly involved in female meiosis I
0.50	GO:0031116	positive regulation of microtubule polymerization
0.39	GO:0030705	cytoskeleton-dependent intracellular transport
0.37	GO:0000301	retrograde transport, vesicle recycling within Golgi
0.37	GO:0071963	establishment or maintenance of cell polarity regulating cell shape
0.36	GO:0007005	mitochondrion organization
0.35	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0016887	ATPase activity
0.35	GO:0000213	tRNA-intron endonuclease activity
0.34	GO:0003676	nucleic acid binding
0.33	GO:0003779	actin binding

0.62	GO:0005874	microtubule
0.51	GO:0005871	kinesin complex
0.35	GO:0005737	cytoplasm
0.34	GO:0031967	organelle envelope
0.34	GO:0031090	organelle membrane
0.34	GO:0044441	ciliary part
0.33	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0090543	Flemming body
0.33	GO:0051233	spindle midzone
0.32	GO:0071944	cell periphery

0.39

GO:0016887

sp|P18106|FER_DROME
Tyrosine-protein kinase Fer
Search

0.28	Tyrosine-protein kinase Fer

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.49	GO:0046664	dorsal closure, amnioserosa morphology change
0.49	GO:0007394	dorsal closure, elongation of leading edge cells
0.46	GO:0051017	actin filament bundle assembly
0.45	GO:0007411	axon guidance
0.40	GO:0046777	protein autophosphorylation
0.39	GO:0045087	innate immune response
0.39	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.39	GO:0016477	cell migration
0.39	GO:0042127	regulation of cell proliferation

0.76	GO:0004713	protein tyrosine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0005102	receptor binding
0.38	GO:0005543	phospholipid binding
0.35	GO:0008270	zinc ion binding
0.35	GO:0019135	deoxyhypusine monooxygenase activity
0.33	GO:0003676	nucleic acid binding

0.45	GO:0005912	adherens junction
0.44	GO:0019898	extrinsic component of membrane
0.39	GO:0009898	cytoplasmic side of plasma membrane
0.33	GO:0044424	intracellular part

0.76

GO:0004713

sp|P18167|ESTP_DROME
Esterase P
Search

0.43	Carboxylic ester hydrolase

0.55	GO:0042811	pheromone biosynthetic process
0.53	GO:0007619	courtship behavior
0.43	GO:1901575	organic substance catabolic process
0.37	GO:0046693	sperm storage
0.37	GO:0046008	regulation of female receptivity, post-mating
0.36	GO:0030728	ovulation
0.36	GO:0046662	regulation of oviposition
0.33	GO:0060179	male mating behavior

0.58

GO:0052689

carboxylic ester hydrolase activity

0.50	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

0.58	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.58	KEGG:R00630	GO:0052689

sp|P18168|SERR_DROME
Protein serrate
Search

0.75	GO:0007219	Notch signaling pathway
0.65	GO:0007275	multicellular organism development
0.34	GO:0006898	receptor-mediated endocytosis
0.30	GO:0002683	negative regulation of immune system process
0.30	GO:0045746	negative regulation of Notch signaling pathway
0.30	GO:0060429	epithelium development
0.30	GO:0045610	regulation of hemocyte differentiation
0.30	GO:0046331	lateral inhibition
0.30	GO:0009653	anatomical structure morphogenesis
0.30	GO:0045596	negative regulation of cell differentiation

0.74	GO:0005112	Notch binding
0.65	GO:0005509	calcium ion binding
0.34	GO:0005044	scavenger receptor activity
0.31	GO:0016740	transferase activity

0.30	GO:0030673	axolemma
0.30	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane
0.30	GO:0016324	apical plasma membrane

0.31

GO:0016740

sp|P18171|DEC13_DROME
Defective chorion-1 protein, FC177 isoform
Search

DEC-1

0.97	Defective chorion 1, isoform G

0.85	GO:0007304	chorion-containing eggshell formation
0.60	GO:0010927	cellular component assembly involved in morphogenesis
0.36	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0009966	regulation of signal transduction
0.34	GO:0048522	positive regulation of cellular process
0.34	GO:0023056	positive regulation of signaling
0.34	GO:0032053	ciliary basal body organization
0.34	GO:0048584	positive regulation of response to stimulus
0.34	GO:0051568	histone H3-K4 methylation
0.34	GO:0007288	sperm axoneme assembly

0.86	GO:0005213	structural constituent of chorion
0.37	GO:0001104	RNA polymerase II transcription cofactor activity
0.34	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.34	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.33	GO:0042302	structural constituent of cuticle
0.33	GO:0003713	transcription coactivator activity
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0008168	methyltransferase activity
0.33	GO:0001095	TFIIE-class transcription factor binding

0.85	GO:0042600	chorion
0.65	GO:0005576	extracellular region
0.37	GO:0044451	nucleoplasm part
0.35	GO:0043234	protein complex
0.34	GO:1990234	transferase complex
0.33	GO:0036064	ciliary basal body
0.33	GO:0005814	centriole
0.33	GO:0005700	polytene chromosome
0.32	GO:0000812	Swr1 complex
0.32	GO:1905368	peptidase complex

0.33

GO:0008168

sp|P18173|DHGL_DROME
Glucose dehydrogenase [FAD, quinone]
Search

GLD

0.38	Glucose dehydrogenase

0.53	GO:0046693	sperm storage
0.53	GO:0055114	oxidation-reduction process
0.37	GO:0008364	pupal chitin-based cuticle development
0.34	GO:0006006	glucose metabolic process
0.34	GO:0030245	cellulose catabolic process

0.66	GO:0050660	flavin adenine dinucleotide binding
0.65	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.34	GO:0008810	cellulase activity
0.32	GO:0016874	ligase activity

0.35	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.65

EC:1.1

GO:0016614

sp|P18289|JRA_DROME
Transcription factor AP-1
Search

0.87	LOW QUALITY PROTEIN: transcription factor AP-1

0.63	GO:0006357	regulation of transcription by RNA polymerase II
0.57	GO:0046844	micropyle formation
0.56	GO:0008348	negative regulation of antimicrobial humoral response
0.55	GO:0046528	imaginal disc fusion
0.54	GO:0051124	synaptic growth at neuromuscular junction
0.54	GO:0046843	dorsal appendage formation
0.54	GO:0045823	positive regulation of heart contraction
0.54	GO:0007391	dorsal closure
0.53	GO:0007254	JNK cascade
0.52	GO:0010259	multicellular organism aging

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.48	GO:0046982	protein heterodimerization activity
0.40	GO:0003713	transcription coactivator activity
0.40	GO:0001067	regulatory region nucleic acid binding
0.39	GO:0008013	beta-catenin binding
0.37	GO:0008134	transcription factor binding
0.33	GO:0003682	chromatin binding
0.33	GO:0003723	RNA binding

0.56	GO:0005634	nucleus
0.50	GO:0005667	transcription factor complex
0.38	GO:0000785	chromatin
0.38	GO:0005737	cytoplasm
0.37	GO:0070013	intracellular organelle lumen
0.30	GO:0016020	membrane

sp|P18431|SGG_DROME
Protein kinase shaggy
Search

SGG

0.46	Glycogen synthase kinase-3 beta

0.63	GO:0006468	protein phosphorylation
0.36	GO:0090163	establishment of epithelial cell planar polarity
0.36	GO:0030589	pseudocleavage involved in syncytial blastoderm formation
0.36	GO:0035309	wing and notum subfield formation
0.36	GO:0035293	chitin-based larval cuticle pattern formation
0.36	GO:0046959	habituation
0.36	GO:0045610	regulation of hemocyte differentiation
0.36	GO:0043508	negative regulation of JUN kinase activity
0.36	GO:0008355	olfactory learning
0.36	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.33	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.36	GO:0035324	female germline ring canal
0.36	GO:0045169	fusome
0.35	GO:0031594	neuromuscular junction
0.35	GO:0072686	mitotic spindle
0.35	GO:0030424	axon
0.35	GO:0005813	centrosome
0.35	GO:0005938	cell cortex
0.34	GO:0030054	cell junction
0.34	GO:0005654	nucleoplasm
0.34	GO:0005829	cytosol

sp|P18432|MLR_DROME
Myosin regulatory light chain 2
Search

0.77	Myosin regulatory light chain

0.51	GO:0060361	flight
0.49	GO:0030239	myofibril assembly
0.48	GO:0003012	muscle system process
0.36	GO:0006801	superoxide metabolic process
0.32	GO:0032506	cytokinetic process
0.32	GO:0033512	L-lysine catabolic process to acetyl-CoA via saccharopine
0.32	GO:0006099	tricarboxylic acid cycle

0.69	GO:0005509	calcium ion binding
0.33	GO:0042834	peptidoglycan binding
0.32	GO:0016751	S-succinyltransferase activity
0.31	GO:0140096	catalytic activity, acting on a protein

0.47	GO:0030016	myofibril
0.36	GO:0016459	myosin complex
0.33	GO:0030428	cell septum
0.32	GO:0005887	integral component of plasma membrane
0.32	GO:0045252	oxoglutarate dehydrogenase complex

0.32

GO:0016751

sp|P18459|TY3H_DROME
Tyrosine 3-monooxygenase
Search

0.73	Biopterin-dependent aromatic amino acid hydroxylase

0.83	GO:0042423	catecholamine biosynthetic process
0.69	GO:0009072	aromatic amino acid family metabolic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:2000274	regulation of epithelial cell migration, open tracheal system
0.52	GO:0048082	regulation of adult chitin-containing cuticle pigmentation
0.52	GO:0043052	thermotaxis
0.52	GO:0040040	thermosensory behavior
0.51	GO:0048085	adult chitin-containing cuticle pigmentation
0.51	GO:0042417	dopamine metabolic process
0.51	GO:0008049	male courtship behavior

0.85	GO:0004511	tyrosine 3-monooxygenase activity
0.63	GO:0005506	iron ion binding
0.37	GO:0003924	GTPase activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0016020

membrane

0.85

EC:1.14.16.2

GO:0004511

sp|P18475|TORSO_DROME
Tyrosine-protein kinase receptor torso
Search

0.86	Tyrosine-protein kinase receptor torso

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.70	GO:0046957	negative phototaxis
0.70	GO:0007278	pole cell fate determination
0.68	GO:0007280	pole cell migration
0.67	GO:0007362	terminal region determination
0.66	GO:0040015	negative regulation of multicellular organism growth
0.64	GO:0007552	metamorphosis
0.62	GO:0007369	gastrulation
0.62	GO:0046777	protein autophosphorylation
0.48	GO:0048477	oogenesis

0.77	GO:0004713	protein tyrosine kinase activity
0.60	GO:0019199	transmembrane receptor protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.35	GO:0046872	metal ion binding
0.34	GO:0005102	receptor binding
0.33	GO:0042802	identical protein binding

0.46	GO:0005886	plasma membrane
0.35	GO:0005911	cell-cell junction
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0019898	extrinsic component of membrane
0.33	GO:0005622	intracellular
0.33	GO:0001726	ruffle
0.32	GO:0031974	membrane-enclosed lumen
0.32	GO:0044422	organelle part
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.77

GO:0004713

sp|P18486|L2AM_DROME
Alpha-methyldopa hypersensitive protein
Search

AMD

0.96	Alpha methyl dopa-resistant

0.60	GO:0006520	cellular amino acid metabolic process
0.49	GO:0040003	chitin-based cuticle development
0.48	GO:0006584	catecholamine metabolic process

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.44	GO:0019239	deaminase activity
0.37	GO:0042302	structural constituent of cuticle

0.68

EC:4.1.1

GO:0016831

sp|P18487|A37C_DROME
Protein anon-37Cs
Search

0.42	Flavin containing amine oxidoreductase

0.53	GO:0055114	oxidation-reduction process
0.38	GO:0016117	carotenoid biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.54	GO:0016491	oxidoreductase activity
0.33	GO:0020037	heme binding
0.33	GO:0046914	transition metal ion binding
0.32	GO:0003677	DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.42	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.54

GO:0016491

sp|P18488|EMS_DROME
Homeotic protein empty spiracles
Search

0.89	Homeotic protein empty spiracles

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0007420	brain development
0.54	GO:0035283	central nervous system segmentation
0.53	GO:0014019	neuroblast development
0.53	GO:0035277	spiracle morphogenesis, open tracheal system
0.53	GO:0030182	neuron differentiation
0.52	GO:0007419	ventral cord development
0.51	GO:0001700	embryonic development via the syncytial blastoderm

0.64	GO:0043565	sequence-specific DNA binding
0.50	GO:0035326	enhancer binding
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003690	double-stranded DNA binding
0.32	GO:0005515	protein binding

0.61

GO:0005634

nucleus

sp|P18489|SYB_DROME
Synaptobrevin
Search

SYB

0.63	Vesicle-associated membrane protein 8

0.69	GO:0016192	vesicle-mediated transport
0.44	GO:0090174	organelle membrane fusion
0.43	GO:0016050	vesicle organization
0.39	GO:0097480	establishment of synaptic vesicle localization
0.39	GO:0099504	synaptic vesicle cycle
0.39	GO:0099643	signal release from synapse
0.39	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.38	GO:0140056	organelle localization by membrane tethering
0.38	GO:0006836	neurotransmitter transport
0.37	GO:0001505	regulation of neurotransmitter levels

0.44	GO:0000149	SNARE binding
0.44	GO:0005484	SNAP receptor activity

0.44	GO:0031201	SNARE complex
0.43	GO:0043195	terminal bouton
0.43	GO:0008021	synaptic vesicle
0.42	GO:0048786	presynaptic active zone
0.36	GO:0005886	plasma membrane
0.35	GO:0099501	exocytic vesicle membrane
0.34	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

sp|P18490|PCX_DROME
Protein pecanex
Search

0.45	GO:0007029	endoplasmic reticulum organization
0.45	GO:0007219	Notch signaling pathway
0.43	GO:0007399	nervous system development
0.42	GO:0030154	cell differentiation

0.42	GO:0005783	endoplasmic reticulum
0.30	GO:0044425	membrane part

sp|P18491|EMC_DROME
Protein extra-macrochaetae
Search

EMC

0.59	Helix-loop-helix DNA-binding domain protein

0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.62	GO:0007458	progression of morphogenetic furrow involved in compound eye morphogenesis
0.62	GO:0042675	compound eye cone cell differentiation
0.61	GO:0030381	chorion-containing eggshell pattern formation
0.61	GO:0048056	R3/R4 cell differentiation
0.60	GO:0045466	R7 cell differentiation
0.60	GO:0008258	head involution
0.60	GO:0007494	midgut development
0.60	GO:0046552	photoreceptor cell fate commitment
0.60	GO:0046843	dorsal appendage formation

0.68	GO:0046983	protein dimerization activity
0.58	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.37	GO:0003677	DNA binding
0.33	GO:0001104	RNA polymerase II transcription cofactor activity
0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0008168	methyltransferase activity
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.33	GO:0031514	motile cilium
0.32	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0008168

sp|P18502|PTC_DROME
Protein patched
Search

0.71

Patched

0.57	GO:0055034	Bolwig's organ development
0.57	GO:0035225	determination of genital disc primordium
0.57	GO:2000274	regulation of epithelial cell migration, open tracheal system
0.56	GO:0007455	eye-antennal disc morphogenesis
0.55	GO:0045879	negative regulation of smoothened signaling pathway
0.53	GO:0007476	imaginal disc-derived wing morphogenesis
0.53	GO:0007224	smoothened signaling pathway
0.53	GO:0008406	gonad development
0.53	GO:0055088	lipid homeostasis
0.52	GO:0048592	eye morphogenesis

0.73	GO:0008158	hedgehog receptor activity
0.55	GO:0030228	lipoprotein particle receptor activity
0.35	GO:0005515	protein binding
0.35	GO:0004149	dihydrolipoyllysine-residue succinyltransferase activity
0.34	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0015485	cholesterol binding
0.33	GO:0008201	heparin binding
0.33	GO:0044877	macromolecular complex binding

0.55	GO:0045169	fusome
0.52	GO:0030139	endocytic vesicle
0.51	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005929	cilium
0.46	GO:0005887	integral component of plasma membrane
0.36	GO:0005794	Golgi apparatus
0.35	GO:0045252	oxoglutarate dehydrogenase complex
0.34	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.34	GO:0044294	dendritic growth cone
0.34	GO:0044295	axonal growth cone

0.35

EC:2.3.1.61

GO:0004149

sp|P18537|FRIZ_DROME
Frizzled
Search

0.79	Wnt-activated receptor

0.76	GO:0016055	Wnt signaling pathway
0.65	GO:0007275	multicellular organism development
0.52	GO:0022606	establishment of proximal/distal cell polarity
0.52	GO:0031346	positive regulation of cell projection organization
0.51	GO:0010720	positive regulation of cell development
0.51	GO:0051962	positive regulation of nervous system development
0.51	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.50	GO:0022412	cellular process involved in reproduction in multicellular organism
0.50	GO:0000904	cell morphogenesis involved in differentiation
0.50	GO:0035206	regulation of hemocyte proliferation

0.83	GO:0042813	Wnt-activated receptor activity
0.54	GO:0017147	Wnt-protein binding
0.44	GO:0001540	amyloid-beta binding
0.44	GO:0030165	PDZ domain binding
0.44	GO:0019955	cytokine binding
0.43	GO:0031625	ubiquitin protein ligase binding
0.42	GO:0042803	protein homodimerization activity
0.41	GO:0046982	protein heterodimerization activity
0.40	GO:0004930	G-protein coupled receptor activity

0.46	GO:0106003	amyloid-beta complex
0.45	GO:0005768	endosome
0.43	GO:0030425	dendrite
0.43	GO:0005887	integral component of plasma membrane
0.42	GO:0009986	cell surface
0.42	GO:0005911	cell-cell junction
0.33	GO:0030669	clathrin-coated endocytic vesicle membrane
0.33	GO:0070062	extracellular exosome

sp|P18824|ARM_DROME
Armadillo segment polarity protein
Search

ARM

0.71	Armadillo/beta-catenin/plakoglobin

0.85	GO:0034333	adherens junction assembly
0.61	GO:0007165	signal transduction
0.44	GO:0007367	segment polarity determination
0.43	GO:0014016	neuroblast differentiation
0.42	GO:0046667	compound eye retinal cell programmed cell death
0.42	GO:0048526	imaginal disc-derived wing expansion
0.42	GO:0035153	epithelial cell type specification, open tracheal system
0.42	GO:0090254	cell elongation involved in imaginal disc-derived wing morphogenesis
0.42	GO:0071896	protein localization to adherens junction
0.41	GO:0198738	cell-cell signaling by wnt

0.64	GO:0004871	signal transducer activity
0.41	GO:0001105	RNA polymerase II transcription coactivator activity
0.40	GO:0045296	cadherin binding
0.39	GO:0019899	enzyme binding
0.39	GO:0008134	transcription factor binding
0.39	GO:0045294	alpha-catenin binding
0.38	GO:0032403	protein complex binding
0.33	GO:0022836	gated channel activity
0.33	GO:0005216	ion channel activity

0.43	GO:0016342	catenin complex
0.42	GO:0005912	adherens junction
0.41	GO:1990907	beta-catenin-TCF complex
0.40	GO:0016324	apical plasma membrane
0.40	GO:0030139	endocytic vesicle
0.39	GO:0043296	apical junction complex
0.39	GO:0030424	axon
0.34	GO:0005654	nucleoplasm
0.34	GO:0005829	cytosol
0.33	GO:0005856	cytoskeleton

sp|P18929|NU1M_DROME
NADH-ubiquinone oxidoreductase chain 1
Search

ND1

0.47	NADH-ubiquinone oxidoreductase chain 1

0.53	GO:0055114	oxidation-reduction process
0.33	GO:0006091	generation of precursor metabolites and energy

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.36	GO:0070469	respiratory chain
0.35	GO:0030964	NADH dehydrogenase complex
0.34	GO:0098798	mitochondrial protein complex
0.34	GO:1990204	oxidoreductase complex
0.33	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|P18930|NU3M_DROME
NADH-ubiquinone oxidoreductase chain 3
Search

ND3

0.47	NADH-ubiquinone oxidoreductase chain 3

0.53

GO:0055114

oxidation-reduction process

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.60	GO:0070469	respiratory chain
0.60	GO:0031967	organelle envelope
0.59	GO:0031090	organelle membrane
0.36	GO:0030964	NADH dehydrogenase complex
0.35	GO:1990204	oxidoreductase complex
0.34	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|P18931|NU4M_DROME
NADH-ubiquinone oxidoreductase chain 4
Search

MT:ND4

0.45	NADH-ubiquinone oxidoreductase chain 4

0.72

GO:0006120

mitochondrial electron transport, NADH to ubiquinone

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.30	GO:0031967	organelle envelope
0.30	GO:0070469	respiratory chain
0.30	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|P18932|NU5M_DROME
NADH-ubiquinone oxidoreductase chain 5
Search

ND5

0.46	NADH-ubiquinone oxidoreductase chain 5

0.69

GO:0042773

ATP synthesis coupled electron transport

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|P18933|NU6M_DROME
NADH-ubiquinone oxidoreductase chain 6
Search

ND6

0.49	NADH-ubiquinone oxidoreductase chain 6

0.53

GO:0055114

oxidation-reduction process

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.34	GO:0070469	respiratory chain
0.34	GO:0031967	organelle envelope
0.34	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|P18934|NU4LM_DROME
NADH-ubiquinone oxidoreductase chain 4L
Search

MT:ND4L

0.50	NADH-ubiquinone oxidoreductase chain 4L

0.66

GO:0042773

ATP synthesis coupled electron transport

0.66

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.35	GO:0070469	respiratory chain
0.34	GO:0031967	organelle envelope
0.34	GO:0031090	organelle membrane
0.34	GO:0030964	NADH dehydrogenase complex
0.33	GO:1990204	oxidoreductase complex
0.33	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.66

GO:0008137

sp|P18935|CYB_DROME
Cytochrome b
Search

CYTB

0.41	Cytochrome b

0.67	GO:0022904	respiratory electron transport chain
0.54	GO:0006119	oxidative phosphorylation
0.34	GO:0007283	spermatogenesis

0.62	GO:0009055	electron transfer activity
0.62	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.52	GO:0046872	metal ion binding

0.61	GO:0045275	respiratory chain complex III
0.61	GO:0005739	mitochondrion
0.60	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.62

EC:1.10.2

GO:0016681

sp|P19018|TRA2_DROME
Transformer-2 sex-determining protein
Search

0.88	Transformer-2 protein like protein beta

0.54	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.50	GO:0000398	mRNA splicing, via spliceosome
0.50	GO:0021796	cerebral cortex regionalization
0.49	GO:1990403	embryonic brain development
0.49	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.49	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.49	GO:0030237	female sex determination
0.48	GO:0071333	cellular response to glucose stimulus
0.44	GO:0051259	protein oligomerization
0.37	GO:0019102	male somatic sex determination

0.59	GO:0003723	RNA binding
0.49	GO:0042802	identical protein binding
0.45	GO:0019904	protein domain specific binding
0.36	GO:0008233	peptidase activity
0.33	GO:0003872	6-phosphofructokinase activity

0.47	GO:0005637	nuclear inner membrane
0.46	GO:0005681	spliceosomal complex
0.43	GO:0005654	nucleoplasm
0.35	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0008233

sp|P19107|ARRB_DROME
Phosrestin-1
Search

0.74	Arrestin (Or S-antigen)

0.61	GO:0007165	signal transduction
0.49	GO:0016060	metarhodopsin inactivation
0.48	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin
0.48	GO:0036367	light adaption
0.46	GO:0045494	photoreceptor cell maintenance
0.45	GO:0007605	sensory perception of sound
0.44	GO:0071482	cellular response to light stimulus
0.44	GO:0009584	detection of visible light
0.43	GO:0007608	sensory perception of smell
0.39	GO:0007601	visual perception

0.36	GO:0002046	opsin binding
0.34	GO:0008073	ornithine decarboxylase inhibitor activity
0.33	GO:0004022	alcohol dehydrogenase (NAD) activity

0.48	GO:0016029	subrhabdomeral cisterna
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:1.1.1.1

GO:0004022

sp|P19109|DDX17_DROME
ATP-dependent RNA helicase p62
Search

DDX17

0.38	DEAD box ATP-dependent RNA helicase

0.43	GO:0016246	RNA interference
0.43	GO:0019730	antimicrobial humoral response
0.43	GO:0050688	regulation of defense response to virus
0.37	GO:0006468	protein phosphorylation
0.36	GO:0010501	RNA secondary structure unwinding
0.34	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0045893	positive regulation of transcription, DNA-templated
0.33	GO:0006508	proteolysis
0.30	GO:0006950	response to stress
0.30	GO:0000381	regulation of alternative mRNA splicing, via spliceosome

0.66	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.37	GO:0004672	protein kinase activity
0.35	GO:0008186	RNA-dependent ATPase activity
0.34	GO:0004222	metalloendopeptidase activity
0.34	GO:0140098	catalytic activity, acting on RNA
0.33	GO:0008270	zinc ion binding

0.44	GO:0005703	polytene chromosome puff
0.38	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.32	GO:0005737	cytoplasm
0.30	GO:1990904	ribonucleoprotein complex
0.30	GO:0016020	membrane
0.30	GO:1902494	catalytic complex

0.34

EC:3.4.24

GO:0004222

sp|P19334|TRP_DROME
Transient receptor potential protein
Search

0.59	Short transient receptor potential channel

0.77	GO:0070588	calcium ion transmembrane transport
0.54	GO:0008377	light-induced release of internally sequestered calcium ion
0.52	GO:0071454	cellular response to anoxia
0.52	GO:0008355	olfactory learning
0.51	GO:0050908	detection of light stimulus involved in visual perception
0.50	GO:0001895	retina homeostasis
0.49	GO:0007605	sensory perception of sound
0.46	GO:0007005	mitochondrion organization
0.43	GO:0008104	protein localization
0.41	GO:0006828	manganese ion transport

0.80	GO:0005262	calcium channel activity
0.51	GO:0010461	light-activated ion channel activity
0.46	GO:0042803	protein homodimerization activity
0.46	GO:0046982	protein heterodimerization activity
0.36	GO:0005516	calmodulin binding

0.53	GO:0035997	rhabdomere microvillus membrane
0.53	GO:0016027	inaD signaling complex
0.47	GO:0034703	cation channel complex
0.38	GO:0005887	integral component of plasma membrane

sp|P19339|SXL_DROME
Protein sex-lethal
Search

SXL

0.36	Sex lethal

0.77	GO:0000380	alternative mRNA splicing, via spliceosome
0.74	GO:0007530	sex determination
0.40	GO:0042742	defense response to bacterium
0.37	GO:0007548	sex differentiation
0.37	GO:0007446	imaginal disc growth
0.36	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.36	GO:0007549	dosage compensation
0.36	GO:0030154	cell differentiation
0.36	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.36	GO:0007224	smoothened signaling pathway

0.59	GO:0003723	RNA binding
0.36	GO:0000900	translation repressor activity, nucleic acid binding
0.34	GO:0005515	protein binding

0.34	GO:0005634	nucleus
0.33	GO:0043234	protein complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P19351|TNNT_DROME
Troponin T, skeletal muscle
Search

0.95	Troponin T, skeletal muscle

0.83	GO:0006937	regulation of muscle contraction
0.35	GO:0030240	skeletal muscle thin filament assembly
0.35	GO:0046716	muscle cell cellular homeostasis
0.35	GO:0045214	sarcomere organization
0.35	GO:0048644	muscle organ morphogenesis
0.34	GO:0007498	mesoderm development
0.34	GO:0006874	cellular calcium ion homeostasis
0.34	GO:0007005	mitochondrion organization

0.33

GO:0005509

calcium ion binding

0.84

GO:0005861

troponin complex

sp|P19538|CI_DROME
Transcriptional activator cubitus interruptus
Search

0.74	Transcriptional activator cubitus interruptus

0.58	GO:0035217	labial disc development
0.57	GO:0048100	wing disc anterior/posterior pattern formation
0.57	GO:0035224	genital disc anterior/posterior pattern formation
0.56	GO:0035277	spiracle morphogenesis, open tracheal system
0.56	GO:0007367	segment polarity determination
0.56	GO:0035017	cuticle pattern formation
0.55	GO:0002385	mucosal immune response
0.55	GO:0060914	heart formation
0.54	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.54	GO:0030858	positive regulation of epithelial cell differentiation

0.55	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.54	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.52	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.49	GO:0042803	protein homodimerization activity
0.35	GO:0046872	metal ion binding
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0003682	chromatin binding

0.57	GO:0035301	Hedgehog signaling complex
0.44	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

GO:0004252

sp|P19889|RLA0_DROME
60S acidic ribosomal protein P0
Search

0.67	60S acidic ribosomal protein P0

0.66	GO:0042254	ribosome biogenesis
0.42	GO:0006284	base-excision repair
0.39	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.34	GO:0002181	cytoplasmic translation

0.43	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity
0.41	GO:0005509	calcium ion binding
0.40	GO:0004519	endonuclease activity
0.39	GO:0000287	magnesium ion binding
0.35	GO:0003735	structural constituent of ribosome
0.33	GO:0005515	protein binding

0.60	GO:0005840	ribosome
0.45	GO:0016363	nuclear matrix
0.41	GO:0005829	cytosol
0.41	GO:0005654	nucleoplasm
0.35	GO:0036464	cytoplasmic ribonucleoprotein granule
0.35	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.43

EC:4.2.99.18

GO:0003906

sp|P19967|CYB5R_DROME
Cytochrome b5-related protein
Search

0.41	Putative delta 6-fatty acid desaturase/delta-8 sphingolipid desaturase

0.62	GO:0006629	lipid metabolic process
0.49	GO:0055114	oxidation-reduction process

0.58	GO:0020037	heme binding
0.50	GO:0046872	metal ion binding
0.50	GO:0016491	oxidoreductase activity
0.33	GO:0016758	transferase activity, transferring hexosyl groups

0.42	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.50

GO:0016491

sp|P20007|PCKG_DROME
Phosphoenolpyruvate carboxykinase [GTP]
Search

0.46	Phosphoenolpyruvate carboxykinase

0.73	GO:0006094	gluconeogenesis
0.49	GO:0016310	phosphorylation
0.35	GO:0090664	response to high population density

0.82	GO:0004613	phosphoenolpyruvate carboxykinase (GTP) activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0016301	kinase activity
0.34	GO:0004612	phosphoenolpyruvate carboxykinase (ATP) activity
0.33	GO:0046872	metal ion binding

0.35

GO:0005739

mitochondrion

0.82	EC:4.1.1.32	GO:0004613
0.34	KEGG:R00341	GO:0004612

sp|P20009|DLL_DROME
Homeotic protein distal-less
Search

DLL

0.74	Homeotic transcription factor dll

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.38	GO:0007487	analia development
0.38	GO:0035213	clypeo-labral disc development
0.38	GO:0021553	olfactory nerve development
0.38	GO:0007479	leg disc proximal/distal pattern formation
0.38	GO:0048264	determination of ventral identity
0.38	GO:0007485	imaginal disc-derived male genitalia development
0.38	GO:0007469	antennal development

0.61

GO:0043565

sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P20028|RPA2_DROME
DNA-directed RNA polymerase I subunit RPA2
Search

0.41	DNA-directed RNA polymerase subunit beta

0.58	GO:0006351	transcription, DNA-templated
0.51	GO:0045793	positive regulation of cell size
0.48	GO:0016049	cell growth
0.35	GO:0017126	nucleologenesis
0.35	GO:0007566	embryo implantation
0.33	GO:0016072	rRNA metabolic process
0.31	GO:2001141	regulation of RNA biosynthetic process
0.31	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.31	GO:0010468	regulation of gene expression

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.65	GO:0001882	nucleoside binding
0.55	GO:0003677	DNA binding
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding
0.32	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.39	GO:0000428	DNA-directed RNA polymerase complex
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0044446	intracellular organelle part
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0003899

sp|P20153|USP_DROME
Protein ultraspiracle
Search

USP

0.92	Ultraspiracle RXR

0.76	GO:0043401	steroid hormone mediated signaling pathway
0.65	GO:0006697	ecdysone biosynthetic process
0.65	GO:0035073	pupariation
0.63	GO:0071390	cellular response to ecdysone
0.63	GO:0016322	neuron remodeling
0.63	GO:0016319	mushroom body development
0.62	GO:0007298	border follicle cell migration
0.61	GO:0046620	regulation of organ growth
0.60	GO:0007552	metamorphosis
0.58	GO:0006351	transcription, DNA-templated

0.77	GO:0003707	steroid hormone receptor activity
0.67	GO:0035100	ecdysone binding
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0001047	core promoter binding
0.55	GO:0042803	protein homodimerization activity
0.55	GO:0046982	protein heterodimerization activity
0.54	GO:0005102	receptor binding
0.54	GO:0003690	double-stranded DNA binding

0.67	GO:0008232	activator ecdysone receptor complex
0.58	GO:0030425	dendrite
0.40	GO:0005700	polytene chromosome

sp|P20193|SUV37_DROME
Protein suppressor of variegation 3-7
Search

0.82	Protein suppressor of variegation 3-7

0.79	GO:0090053	positive regulation of chromatin silencing at centromere
0.76	GO:0009047	dosage compensation by hyperactivation of X chromosome
0.74	GO:0031453	positive regulation of heterochromatin assembly

0.64	GO:0003682	chromatin binding
0.54	GO:0003677	DNA binding
0.40	GO:0005515	protein binding
0.38	GO:0046872	metal ion binding

0.70	GO:0005721	pericentric heterochromatin
0.61	GO:0005634	nucleus
0.49	GO:0005701	polytene chromosome chromocenter

sp|P20227|TBP_DROME
TATA-box-binding protein
Search

TBP

0.27	Putative tata-box binding protein tbp component of tfiid and tfiiib

0.69	GO:0006352	DNA-templated transcription, initiation
0.47	GO:0042796	snRNA transcription by RNA polymerase III
0.47	GO:0042795	snRNA transcription by RNA polymerase II
0.47	GO:0006359	regulation of transcription by RNA polymerase III
0.46	GO:0042797	tRNA transcription by RNA polymerase III
0.46	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter
0.44	GO:0001035	transcription by RNA polymerase III
0.43	GO:0065004	protein-DNA complex assembly
0.37	GO:0009790	embryo development
0.36	GO:0060962	regulation of ribosomal protein gene transcription by RNA polymerase II

0.55	GO:0003677	DNA binding
0.48	GO:0001092	TFIIA-class transcription factor binding
0.47	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly
0.46	GO:0001129	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly
0.43	GO:0001067	regulatory region nucleic acid binding
0.43	GO:0003682	chromatin binding
0.41	GO:0001034	RNA polymerase III transcription factor activity, sequence-specific DNA binding
0.35	GO:0003743	translation initiation factor activity
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0097506	deaminated base DNA N-glycosylase activity

0.46	GO:0005669	transcription factor TFIID complex
0.45	GO:0000126	transcription factor TFIIIB complex
0.35	GO:0005666	DNA-directed RNA polymerase III complex
0.32	GO:0005737	cytoplasm

0.34

GO:0032440

sp|P20228|DCE_DROME
Glutamate decarboxylase
Search

0.41	Glutamate decarboxylase

0.57	GO:0019752	carboxylic acid metabolic process
0.49	GO:0045213	neurotransmitter receptor metabolic process
0.48	GO:0008355	olfactory learning
0.48	GO:0008345	larval locomotory behavior
0.47	GO:0007528	neuromuscular junction development
0.46	GO:0007416	synapse assembly
0.46	GO:0009612	response to mechanical stimulus
0.45	GO:0042136	neurotransmitter biosynthetic process
0.41	GO:0016054	organic acid catabolic process
0.41	GO:0051932	synaptic transmission, GABAergic

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.33	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.32	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.31	GO:0030554	adenyl nucleotide binding
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0060077	inhibitory synapse
0.40	GO:0030424	axon
0.40	GO:0098793	presynapse
0.39	GO:0070382	exocytic vesicle
0.39	GO:0043025	neuronal cell body
0.36	GO:0044306	neuron projection terminus
0.35	GO:0005938	cell cortex
0.34	GO:0005829	cytosol
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.68

EC:4.1.1

GO:0016831

sp|P20232|TFS2_DROME
Transcription elongation factor S-II
Search

0.74	Transcription elongation factor TFIIS

0.59	GO:0006414	translational elongation
0.58	GO:0006351	transcription, DNA-templated
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.37	GO:0034622	cellular macromolecular complex assembly
0.36	GO:0002183	cytoplasmic translational initiation
0.36	GO:0043413	macromolecule glycosylation
0.36	GO:0009101	glycoprotein biosynthetic process
0.36	GO:0071826	ribonucleoprotein complex subunit organization

0.63	GO:0008270	zinc ion binding
0.59	GO:0003746	translation elongation factor activity
0.37	GO:0001139	transcription factor activity, core RNA polymerase II recruiting
0.36	GO:0043022	ribosome binding
0.35	GO:0003743	translation initiation factor activity
0.35	GO:0030246	carbohydrate binding
0.35	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.33	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.36	GO:0016282	eukaryotic 43S preinitiation complex
0.36	GO:0033290	eukaryotic 48S preinitiation complex
0.36	GO:0005852	eukaryotic translation initiation factor 3 complex
0.35	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

0.35

GO:0016757

sp|P20240|OTE_DROME
Otefin
Search

0.92

Otefin

0.85	GO:0060250	germ-line stem-cell niche homeostasis
0.84	GO:0048132	female germ-line stem cell asymmetric division
0.82	GO:0031468	nuclear envelope reassembly
0.81	GO:0030718	germ-line stem cell population maintenance
0.81	GO:0030513	positive regulation of BMP signaling pathway
0.67	GO:0045892	negative regulation of transcription, DNA-templated
0.42	GO:0007049	cell cycle
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.33	GO:0006396	RNA processing

0.76	GO:0003714	transcription corepressor activity
0.68	GO:0008134	transcription factor binding
0.33	GO:0008408	3'-5' exonuclease activity
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding
0.32	GO:0003676	nucleic acid binding

0.77	GO:0005637	nuclear inner membrane
0.76	GO:0034399	nuclear periphery
0.46	GO:0000922	spindle pole
0.45	GO:0005815	microtubule organizing center
0.45	GO:0005654	nucleoplasm
0.42	GO:0005694	chromosome
0.37	GO:0005737	cytoplasm
0.34	GO:0000176	nuclear exosome (RNase complex)
0.30	GO:0031224	intrinsic component of membrane

sp|P20241|NRG_DROME
Neuroglian
Search

NRG

0.81	Cell adhesion molecule

0.37	GO:0021682	nerve maturation
0.37	GO:0008050	female courtship behavior
0.36	GO:0048036	central complex development
0.36	GO:0060857	establishment of glial blood-brain barrier
0.36	GO:0072499	photoreceptor cell axon guidance
0.36	GO:0061343	cell adhesion involved in heart morphogenesis
0.36	GO:0035011	melanotic encapsulation of foreign target
0.36	GO:0007158	neuron cell-cell adhesion
0.36	GO:0045924	regulation of female receptivity
0.36	GO:0019991	septate junction assembly

0.34	GO:0005509	calcium ion binding
0.34	GO:0003714	transcription corepressor activity
0.34	GO:0042393	histone binding
0.33	GO:0004896	cytokine receptor activity

0.37	GO:0005919	pleated septate junction
0.36	GO:0035230	cytoneme
0.36	GO:0016328	lateral plasma membrane
0.36	GO:0030175	filopodium
0.35	GO:0005923	bicellular tight junction
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P20348|JANA_DROME
Sex-regulated protein janus-A
Search

JANA

0.91	Sex-regulated protein janus-A

0.76	GO:0007548	sex differentiation
0.55	GO:0030154	cell differentiation
0.55	GO:0035971	peptidyl-histidine dephosphorylation
0.38	GO:0043248	proteasome assembly
0.38	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.37	GO:0051028	mRNA transport
0.37	GO:0006405	RNA export from nucleus
0.34	GO:0010467	gene expression

0.42	GO:0101006	protein histidine phosphatase activity
0.35	GO:0008270	zinc ion binding
0.34	GO:0003676	nucleic acid binding

0.45	GO:0005829	cytosol
0.38	GO:0008541	proteasome regulatory particle, lid subcomplex
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P20349|JANB_DROME
Sex-regulated protein janus-B
Search

JANB

0.97	Sex-regulated protein janus-B

0.81	GO:0007548	sex differentiation
0.67	GO:0030154	cell differentiation
0.50	GO:0035971	peptidyl-histidine dephosphorylation

0.43	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P20350|RHOM_DROME
Protein rhomboid
Search

0.58	Rhomboid-like protein (Fragment)

0.61	GO:0006508	proteolysis
0.53	GO:0007424	open tracheal system development
0.51	GO:0045165	cell fate commitment
0.51	GO:0038004	epidermal growth factor receptor ligand maturation
0.50	GO:0007438	oenocyte development
0.50	GO:0009887	animal organ morphogenesis
0.50	GO:0030182	neuron differentiation
0.50	GO:0061331	epithelial cell proliferation involved in Malpighian tubule morphogenesis
0.50	GO:0035309	wing and notum subfield formation
0.49	GO:0035215	genital disc development

0.69	GO:0004252	serine-type endopeptidase activity
0.43	GO:0005509	calcium ion binding

0.51	GO:0045177	apical part of cell
0.46	GO:0012505	endomembrane system
0.41	GO:0043231	intracellular membrane-bounded organelle
0.41	GO:0044444	cytoplasmic part
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0031984	organelle subcompartment
0.33	GO:0005887	integral component of plasma membrane

0.69

GO:0004252

sp|P20351|T23O_DROME
Tryptophan 2,3-dioxygenase
Search

0.62	Tryptophan 2,3-dioxygenase

0.78	GO:0019441	tryptophan catabolic process to kynurenine
0.75	GO:0033060	ocellus pigmentation
0.74	GO:0006726	eye pigment biosynthetic process
0.63	GO:0044550	secondary metabolite biosynthetic process
0.54	GO:0051289	protein homotetramerization
0.53	GO:0055114	oxidation-reduction process
0.52	GO:1901216	positive regulation of neuron death
0.48	GO:0018130	heterocycle biosynthetic process
0.48	GO:1901362	organic cyclic compound biosynthetic process
0.48	GO:0019438	aromatic compound biosynthetic process

0.83	GO:0004833	tryptophan 2,3-dioxygenase activity
0.63	GO:0020037	heme binding
0.54	GO:0046872	metal ion binding
0.40	GO:0042802	identical protein binding
0.39	GO:0008234	cysteine-type peptidase activity
0.34	GO:0005089	Rho guanyl-nucleotide exchange factor activity

0.32	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.83

EC:1.13.11.11

GO:0004833

sp|P20353|GNAI_DROME
G protein alpha i subunit
Search

0.68	G protein alpha i subunit

0.82	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.49	GO:0007212	dopamine receptor signaling pathway
0.49	GO:0016239	positive regulation of macroautophagy
0.49	GO:0051301	cell division
0.47	GO:0032880	regulation of protein localization
0.47	GO:0014045	establishment of endothelial blood-brain barrier
0.46	GO:0060857	establishment of glial blood-brain barrier
0.46	GO:0045167	asymmetric protein localization involved in cell fate determination
0.46	GO:0019991	septate junction assembly
0.46	GO:0046039	GTP metabolic process

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.64	GO:0004871	signal transducer activity
0.50	GO:0019003	GDP binding
0.46	GO:0001664	G-protein coupled receptor binding
0.38	GO:0032794	GTPase activating protein binding
0.37	GO:0003677	DNA binding
0.36	GO:0019904	protein domain specific binding
0.35	GO:0046872	metal ion binding

0.53	GO:0030496	midbody
0.51	GO:0005813	centrosome
0.50	GO:0099738	cell cortex region
0.48	GO:0005730	nucleolus
0.45	GO:1905360	GTPase complex
0.45	GO:0000139	Golgi membrane
0.45	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.45	GO:0005789	endoplasmic reticulum membrane
0.44	GO:0045177	apical part of cell
0.41	GO:0098797	plasma membrane protein complex

sp|P20354|GNAS_DROME
G protein alpha s subunit
Search

0.82	G protein alpha s subunit

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.47	GO:0010353	response to trehalose
0.47	GO:2000253	positive regulation of feeding behavior
0.46	GO:0050916	sensory perception of sweet taste
0.46	GO:0007528	neuromuscular junction development
0.46	GO:0007476	imaginal disc-derived wing morphogenesis
0.44	GO:0007268	chemical synaptic transmission
0.40	GO:0019933	cAMP-mediated signaling
0.36	GO:0007608	sensory perception of smell
0.35	GO:0048148	behavioral response to cocaine

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0001664	G-protein coupled receptor binding
0.34	GO:0046872	metal ion binding

0.47	GO:1905360	GTPase complex
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.44	GO:0005604	basement membrane
0.42	GO:0098797	plasma membrane protein complex
0.30	GO:0016021	integral component of membrane

sp|P20385|CF2_DROME
Chorion transcription factor Cf2
Search

0.91	Chorion transcription factor Cf2

0.44	GO:1903506	regulation of nucleic acid-templated transcription
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.39	GO:0007527	adult somatic muscle development
0.39	GO:0006351	transcription, DNA-templated
0.37	GO:1902680	positive regulation of RNA biosynthetic process
0.34	GO:1902679	negative regulation of RNA biosynthetic process
0.34	GO:0044789	modulation by host of viral release from host cell
0.34	GO:1902188	positive regulation of viral release from host cell
0.34	GO:0044794	positive regulation by host of viral process

0.51	GO:0003676	nucleic acid binding
0.42	GO:0046872	metal ion binding
0.42	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003682	chromatin binding
0.33	GO:0004827	proline-tRNA ligase activity
0.33	GO:0004818	glutamate-tRNA ligase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005634	nucleus
0.33	GO:0005667	transcription factor complex
0.32	GO:0005829	cytosol
0.32	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

EC:6.1.1.15

GO:0004827

sp|P20432|GSTD1_DROME
Glutathione S-transferase D1
Search

GSTD1

0.43	Glutathione S-transferase

0.43	GO:0006749	glutathione metabolic process
0.34	GO:0009636	response to toxic substance
0.33	GO:0070887	cellular response to chemical stimulus

0.50	GO:0018833	DDT-dehydrochlorinase activity
0.49	GO:0016740	transferase activity
0.34	GO:0004602	glutathione peroxidase activity

0.33

GO:0005737

cytoplasm

0.50	EC:4.5.1.1	GO:0018833
0.50	KEGG:R04522	GO:0018833

sp|P20439|CCNB_DROME
G2/mitotic-specific cyclin-B
Search

0.54

Cyclin b

0.51	GO:0035186	syncytial blastoderm mitotic cell cycle
0.51	GO:0007079	mitotic chromosome movement towards spindle pole
0.50	GO:0035561	regulation of chromatin binding
0.49	GO:0000920	cell separation after cytokinesis
0.48	GO:0008608	attachment of spindle microtubules to kinetochore
0.47	GO:0000281	mitotic cytokinesis
0.46	GO:0045859	regulation of protein kinase activity
0.38	GO:0001700	embryonic development via the syncytial blastoderm
0.38	GO:0000086	G2/M transition of mitotic cell cycle
0.35	GO:0043029	T cell homeostasis

0.48	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.36	GO:0005515	protein binding
0.35	GO:0043539	protein serine/threonine kinase activator activity
0.34	GO:0017110	nucleoside-diphosphatase activity
0.33	GO:0005216	ion channel activity
0.33	GO:0016301	kinase activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0097493	structural molecule activity conferring elasticity

0.61	GO:0005634	nucleus
0.49	GO:0051233	spindle midzone
0.48	GO:0072686	mitotic spindle
0.37	GO:0000775	chromosome, centromeric region
0.36	GO:0005815	microtubule organizing center
0.35	GO:0072687	meiotic spindle
0.34	GO:0005829	cytosol
0.34	GO:0000785	chromatin
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0005859	muscle myosin complex

0.48

GO:0016538

sp|P20477|GLNA1_DROME
Glutamine synthetase 1, mitochondrial
Search

0.46	Glutamine synthetase

0.76	GO:0006542	glutamine biosynthetic process
0.47	GO:0006909	phagocytosis
0.44	GO:0007005	mitochondrion organization
0.39	GO:0008283	cell proliferation
0.39	GO:0009749	response to glucose
0.38	GO:0009267	cellular response to starvation
0.36	GO:0051968	positive regulation of synaptic transmission, glutamatergic
0.36	GO:0019676	ammonia assimilation cycle
0.36	GO:0032024	positive regulation of insulin secretion
0.36	GO:0050679	positive regulation of epithelial cell proliferation

0.76	GO:0004356	glutamate-ammonia ligase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0042802	identical protein binding
0.36	GO:0016595	glutamate binding
0.36	GO:0045503	dynein light chain binding
0.35	GO:0004351	glutamate decarboxylase activity
0.34	GO:0030145	manganese ion binding
0.34	GO:0000287	magnesium ion binding

0.42	GO:0005739	mitochondrion
0.39	GO:0097386	glial cell projection
0.38	GO:0043209	myelin sheath
0.38	GO:0044297	cell body
0.38	GO:0005829	cytosol
0.36	GO:0043679	axon terminus
0.35	GO:0005791	rough endoplasmic reticulum
0.35	GO:0036477	somatodendritic compartment
0.34	GO:0070062	extracellular exosome
0.33	GO:0043234	protein complex

0.76	EC:6.3.1.2	GO:0004356
0.76	KEGG:R00253	GO:0004356

sp|P20478|GLNA2_DROME
Glutamine synthetase 2 cytoplasmic
Search

0.46	Glutamine synthetase 2 cytoplasmic

0.76	GO:0006542	glutamine biosynthetic process
0.46	GO:0045213	neurotransmitter receptor metabolic process
0.44	GO:0007416	synapse assembly
0.43	GO:0006538	glutamate catabolic process
0.34	GO:0032094	response to food
0.34	GO:0019676	ammonia assimilation cycle
0.34	GO:0031532	actin cytoskeleton reorganization
0.33	GO:0007155	cell adhesion

0.76	GO:0004356	glutamate-ammonia ligase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003779	actin binding
0.32	GO:0003723	RNA binding

0.34	GO:0034399	nuclear periphery
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.76	EC:6.3.1.2	GO:0004356
0.76	KEGG:R00253	GO:0004356

sp|P20480|NCD_DROME
Protein claret segregational
Search

NCD

0.96	Kinesin protein Ncd

0.74	GO:0007018	microtubule-based movement
0.60	GO:0032837	distributive segregation
0.58	GO:0000022	mitotic spindle elongation
0.58	GO:0032888	regulation of mitotic spindle elongation
0.58	GO:0007100	mitotic centrosome separation
0.57	GO:0090306	spindle assembly involved in meiosis
0.57	GO:1901673	regulation of mitotic spindle assembly
0.55	GO:0090307	mitotic spindle assembly
0.55	GO:0001578	microtubule bundle formation
0.51	GO:0051028	mRNA transport

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0042803	protein homodimerization activity
0.38	GO:0016887	ATPase activity
0.33	GO:0004826	phenylalanine-tRNA ligase activity
0.33	GO:0003676	nucleic acid binding
0.32	GO:0000287	magnesium ion binding

0.68	GO:0005874	microtubule
0.58	GO:0030981	cortical microtubule cytoskeleton
0.57	GO:0072687	meiotic spindle
0.54	GO:0072686	mitotic spindle
0.53	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005813	centrosome
0.45	GO:0005634	nucleus
0.40	GO:0005871	kinesin complex
0.36	GO:0005818	aster
0.35	GO:0000777	condensed chromosome kinetochore

0.38

GO:0016887

sp|P20482|CNC_DROME
Segmentation protein cap'n'collar
Search

0.63	Segmentation protein cap'n'collar

0.61	GO:0008359	regulation of bicoid mRNA localization
0.60	GO:0051663	oocyte nucleus localization involved in oocyte dorsal/ventral axis specification
0.59	GO:0008103	oocyte microtubule cytoskeleton polarization
0.59	GO:0060465	pharynx development
0.59	GO:0007317	regulation of pole plasm oskar mRNA localization
0.58	GO:0045451	pole plasm oskar mRNA localization
0.58	GO:0036335	intestinal stem cell homeostasis
0.58	GO:0045450	bicoid mRNA localization
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.51	GO:0046982	protein heterodimerization activity
0.39	GO:0001067	regulatory region nucleic acid binding

0.61	GO:0005634	nucleus
0.58	GO:0005703	polytene chromosome puff
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P20483|MPIP_DROME
M-phase inducer phosphatase
Search

0.55	M-phase inducer phosphatase

0.84	GO:1902751	positive regulation of cell cycle G2/M phase transition
0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.62	GO:0009794	regulation of mitotic cell cycle, embryonic
0.57	GO:0060305	regulation of cell diameter
0.56	GO:0007488	histoblast morphogenesis
0.55	GO:0045792	negative regulation of cell size
0.55	GO:0045931	positive regulation of mitotic cell cycle
0.54	GO:0040019	positive regulation of embryonic development
0.54	GO:0044839	cell cycle G2/M phase transition
0.54	GO:0010256	endomembrane system organization

0.75	GO:0004725	protein tyrosine phosphatase activity
0.38	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.35	GO:0005515	protein binding
0.34	GO:0004792	thiosulfate sulfurtransferase activity

0.46	GO:0005694	chromosome
0.46	GO:0005634	nucleus
0.42	GO:0005819	spindle
0.34	GO:0005813	centrosome
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.75	EC:3.1.3.48	GO:0004725
0.34	KEGG:R01931	GO:0004792

sp|P20659|TRX_DROME
Histone-lysine N-methyltransferase trithorax
Search

0.42	Histone-lysine N-methyltransferase trithorax

0.74	GO:0034968	histone lysine methylation
0.69	GO:0007482	haltere development
0.67	GO:0008354	germ cell migration
0.65	GO:0043966	histone H3 acetylation
0.62	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.62	GO:0007411	axon guidance
0.61	GO:0001654	eye development
0.55	GO:0006351	transcription, DNA-templated
0.32	GO:0000128	flocculation

0.74	GO:0018024	histone-lysine N-methyltransferase activity
0.66	GO:0008157	protein phosphatase 1 binding
0.61	GO:0004402	histone acetyltransferase activity
0.60	GO:0043565	sequence-specific DNA binding
0.60	GO:0008270	zinc ion binding
0.60	GO:0003682	chromatin binding
0.58	GO:0042803	protein homodimerization activity
0.58	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005199	structural constituent of cell wall
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity

0.69	GO:0035097	histone methyltransferase complex
0.64	GO:0005700	polytene chromosome
0.61	GO:0008023	transcription elongation factor complex
0.59	GO:0000123	histone acetyltransferase complex
0.30	GO:0016020	membrane

0.74

GO:0018024

sp|P20905|5HT1R_DROME
5-hydroxytryptamine receptor 1
Search

0.82	Serotonin receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.60	GO:0016546	male courtship behavior, proboscis-mediated licking
0.60	GO:0016543	male courtship behavior, orientation prior to leg tapping and wing vibration
0.57	GO:0016545	male courtship behavior, veined wing vibration
0.56	GO:0060180	female mating behavior
0.55	GO:0007210	serotonin receptor signaling pathway
0.42	GO:0095500	acetylcholine receptor signaling pathway
0.38	GO:0019933	cAMP-mediated signaling
0.35	GO:0018108	peptidyl-tyrosine phosphorylation

0.72	GO:0004930	G-protein coupled receptor activity
0.61	GO:0030594	neurotransmitter receptor activity
0.55	GO:0099589	serotonin receptor activity
0.40	GO:0051378	serotonin binding
0.35	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.35	GO:0001653	peptide receptor activity

0.54	GO:0005887	integral component of plasma membrane
0.33	GO:0005622	intracellular

0.35

GO:0004715

sp|P21187|PABP_DROME
Polyadenylate-binding protein
Search

0.62	Polyadenylate-binding protein (Fragment)

0.43	GO:0045314	regulation of compound eye photoreceptor development
0.42	GO:0007112	male meiosis cytokinesis
0.42	GO:0007289	spermatid nucleus differentiation
0.41	GO:0048477	oogenesis
0.41	GO:1901215	negative regulation of neuron death
0.41	GO:0009953	dorsal/ventral pattern formation
0.41	GO:0010608	posttranscriptional regulation of gene expression
0.40	GO:0034250	positive regulation of cellular amide metabolic process
0.40	GO:0007268	chemical synaptic transmission
0.40	GO:0032270	positive regulation of cellular protein metabolic process

0.59	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding
0.32	GO:0016491	oxidoreductase activity

0.47	GO:0005737	cytoplasm
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.36	GO:0005634	nucleus
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:1902494	catalytic complex
0.33	GO:0044446	intracellular organelle part

0.32

GO:0016491

sp|P21461|SINA_DROME
E3 ubiquitin-protein ligase sina
Search

0.53	E3 ubiquitin-protein ligase sina

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.73	GO:0016567	protein ubiquitination
0.70	GO:0007275	multicellular organism development
0.48	GO:2000027	regulation of organ morphogenesis
0.47	GO:0051960	regulation of nervous system development
0.46	GO:0060284	regulation of cell development
0.45	GO:0010498	proteasomal protein catabolic process
0.44	GO:0030154	cell differentiation
0.39	GO:0007601	visual perception
0.35	GO:0050896	response to stimulus

0.63	GO:0008270	zinc ion binding
0.48	GO:0043621	protein self-association
0.44	GO:0042802	identical protein binding
0.44	GO:0016874	ligase activity
0.34	GO:0004842	ubiquitin-protein transferase activity

0.61	GO:0005634	nucleus
0.45	GO:0000151	ubiquitin ligase complex
0.37	GO:0005737	cytoplasm

0.44	EC:6	GO:0016874
0.34	KEGG:R03876	GO:0004842

sp|P21519|MAM_DROME
Neurogenic protein mastermind
Search

MAM

0.75	LOW QUALITY PROTEIN: neurogenic protein mastermind

0.79	GO:0007219	Notch signaling pathway
0.78	GO:0007500	mesodermal cell fate determination
0.76	GO:0007475	apposition of dorsal and ventral imaginal disc-derived wing surfaces
0.76	GO:0007418	ventral midline development
0.75	GO:0008407	chaeta morphogenesis
0.73	GO:0030718	germ-line stem cell population maintenance
0.73	GO:0035019	somatic stem cell population maintenance
0.72	GO:0045944	positive regulation of transcription by RNA polymerase II
0.71	GO:0008356	asymmetric cell division
0.70	GO:0030707	ovarian follicle cell development

0.76	GO:0003713	transcription coactivator activity
0.46	GO:0003777	microtubule motor activity
0.42	GO:0008017	microtubule binding
0.34	GO:0003998	acylphosphatase activity

0.77	GO:0016607	nuclear speck
0.74	GO:0005703	polytene chromosome puff
0.42	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.6.1.7

GO:0003998

sp|P21520|SCA_DROME
Protein scabrous
Search

0.83	GO:0016318	ommatidial rotation
0.83	GO:0008407	chaeta morphogenesis
0.82	GO:0008587	imaginal disc-derived wing margin morphogenesis
0.75	GO:0097305	response to alcohol
0.69	GO:0007399	nervous system development
0.51	GO:0045468	regulation of R8 cell spacing in compound eye
0.49	GO:0046331	lateral inhibition
0.48	GO:0016321	female meiosis chromosome segregation
0.46	GO:0007219	Notch signaling pathway
0.39	GO:1903506	regulation of nucleic acid-templated transcription

0.44	GO:0008134	transcription factor binding
0.40	GO:0004871	signal transducer activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0030674	protein binding, bridging
0.34	GO:0005102	receptor binding

0.45	GO:0005770	late endosome
0.42	GO:0005576	extracellular region
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|P21521|SY65_DROME
Synaptotagmin 1
Search

0.73	Synaptotagmin I

0.82	GO:0099643	signal release from synapse
0.82	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.75	GO:0006836	neurotransmitter transport
0.72	GO:0001505	regulation of neurotransmitter levels
0.68	GO:0051649	establishment of localization in cell
0.45	GO:0060627	regulation of vesicle-mediated transport
0.44	GO:0060024	rhythmic synaptic transmission
0.44	GO:1900073	regulation of neuromuscular synaptic transmission
0.44	GO:0007317	regulation of pole plasm oskar mRNA localization
0.44	GO:0017156	calcium ion regulated exocytosis

0.81	GO:0005544	calcium-dependent phospholipid binding
0.43	GO:0000149	SNARE binding
0.43	GO:0001786	phosphatidylserine binding
0.40	GO:0005509	calcium ion binding
0.40	GO:0042803	protein homodimerization activity
0.38	GO:0030276	clathrin binding
0.34	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity

0.81	GO:0008021	synaptic vesicle
0.43	GO:0043195	terminal bouton
0.42	GO:0031594	neuromuscular junction
0.39	GO:0099501	exocytic vesicle membrane
0.34	GO:0031301	integral component of organelle membrane
0.34	GO:0030054	cell junction
0.34	GO:0005886	plasma membrane

0.34	EC:2.7.1.154	GO:0035005
0.34	KEGG:R05795	GO:0035005

sp|P21525|FOSLA_DROME
Transcription factor kayak, isoforms A/B/F
Search

KAY

0.90	Transcription factor kayak

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.66	GO:0048674	collateral sprouting of injured axon
0.65	GO:0031660	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle
0.65	GO:0016330	second mitotic wave involved in compound eye morphogenesis
0.64	GO:0007464	R3/R4 cell fate commitment
0.64	GO:0046528	imaginal disc fusion
0.63	GO:0048085	adult chitin-containing cuticle pigmentation
0.63	GO:0051124	synaptic growth at neuromuscular junction
0.62	GO:0045475	locomotor rhythm
0.61	GO:0007391	dorsal closure

0.61	GO:0003700	DNA binding transcription factor activity
0.61	GO:0070491	repressing transcription factor binding
0.55	GO:0003677	DNA binding
0.54	GO:0046982	protein heterodimerization activity
0.40	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0003777	microtubule motor activity
0.32	GO:0008017	microtubule binding
0.32	GO:0046872	metal ion binding

0.55	GO:0005667	transcription factor complex
0.50	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.39	GO:0070013	intracellular organelle lumen
0.37	GO:0044446	intracellular organelle part
0.33	GO:0098595	perivitelline space
0.33	GO:0030425	dendrite
0.32	GO:0030424	axon
0.32	GO:0099512	supramolecular fiber
0.32	GO:0015630	microtubule cytoskeleton

0.40

GO:0004674

sp|P21663|ANDP_DROME
Andropin
Search

ANP

0.97

Andropin

0.87	GO:0006962	male-specific antibacterial humoral response
0.86	GO:0002816	regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria
0.85	GO:0006963	positive regulation of antibacterial peptide biosynthetic process
0.75	GO:0045087	innate immune response
0.50	GO:0032504	multicellular organism reproduction

0.66

GO:0005576

extracellular region

sp|P21750|SALA_DROME
Protein spalt-accessory
Search

0.58	GO:0007369	gastrulation
0.39	GO:0009607	response to biotic stimulus
0.39	GO:0006812	cation transport
0.38	GO:0009408	response to heat
0.37	GO:0034220	ion transmembrane transport
0.37	GO:0006457	protein folding
0.37	GO:0007508	larval heart development
0.37	GO:0006461	protein complex assembly
0.37	GO:0006260	DNA replication
0.36	GO:0061343	cell adhesion involved in heart morphogenesis

0.42	GO:0003723	RNA binding
0.38	GO:0031072	heat shock protein binding
0.38	GO:0016757	transferase activity, transferring glycosyl groups
0.38	GO:0008324	cation transmembrane transporter activity
0.38	GO:0046872	metal ion binding
0.37	GO:0051082	unfolded protein binding
0.36	GO:0004252	serine-type endopeptidase activity
0.36	GO:0030248	cellulose binding
0.36	GO:0003924	GTPase activity
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.48	GO:0005576	extracellular region
0.36	GO:0005581	collagen trimer
0.35	GO:0019867	outer membrane
0.34	GO:0005886	plasma membrane
0.34	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.38

GO:0016757

sp|P21914|SDHB_DROME
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Search

0.69	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

0.71	GO:0006099	tricarboxylic acid cycle
0.60	GO:0022900	electron transport chain
0.40	GO:0006119	oxidative phosphorylation
0.34	GO:0007264	small GTPase mediated signal transduction
0.33	GO:0065009	regulation of molecular function

0.78	GO:0051538	3 iron, 4 sulfur cluster binding
0.78	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.70	GO:0051537	2 iron, 2 sulfur cluster binding
0.66	GO:0051539	4 iron, 4 sulfur cluster binding
0.61	GO:0009055	electron transfer activity
0.53	GO:0046872	metal ion binding
0.40	GO:0048039	ubiquinone binding
0.34	GO:0005085	guanyl-nucleotide exchange factor activity

0.61	GO:0031966	mitochondrial membrane
0.61	GO:0019866	organelle inner membrane
0.48	GO:0045257	succinate dehydrogenase complex (ubiquinone)
0.48	GO:0045283	fumarate reductase complex
0.44	GO:0098798	mitochondrial protein complex
0.44	GO:0000329	fungal-type vacuole membrane
0.33	GO:0005654	nucleoplasm
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.78	EC:1.3.5.1	GO:0008177
0.78	KEGG:R02164	GO:0008177

sp|P22058|CPD1_DROME
Chromosomal protein D1
Search

0.95	Chromosomal protein D1

0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:1903506	regulation of nucleic acid-templated transcription
0.44	GO:0010468	regulation of gene expression

0.66	GO:0003696	satellite DNA binding
0.65	GO:0003680	AT DNA binding
0.35	GO:0008270	zinc ion binding

0.63	GO:0005700	polytene chromosome
0.62	GO:0000785	chromatin
0.57	GO:0044815	DNA packaging complex
0.55	GO:0032993	protein-DNA complex
0.54	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm

sp|P22265|TSH_DROME
Protein teashirt
Search

0.81	LOW QUALITY PROTEIN: protein teashirt

0.85	GO:0048730	epidermis morphogenesis
0.84	GO:0048749	compound eye development
0.78	GO:0000122	negative regulation of transcription by RNA polymerase II
0.70	GO:0061330	Malpighian tubule stellate cell differentiation
0.69	GO:0007380	specification of segmental identity, head
0.68	GO:0007384	specification of segmental identity, thorax
0.68	GO:2000497	positive regulation of cell proliferation involved in compound eye morphogenesis
0.67	GO:0007473	wing disc proximal/distal pattern formation
0.65	GO:0007479	leg disc proximal/distal pattern formation
0.64	GO:0008258	head involution

0.61	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0003676	nucleic acid binding
0.40	GO:0003682	chromatin binding
0.39	GO:0046872	metal ion binding
0.37	GO:0005515	protein binding

0.49	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm
0.37	GO:0043233	organelle lumen
0.36	GO:0044446	intracellular organelle part

sp|P22270|OAR_DROME
Tyramine/octopamine receptor
Search

0.97	Octopamine-tyramine receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.63	GO:0042310	vasoconstriction
0.62	GO:0007210	serotonin receptor signaling pathway
0.62	GO:0050795	regulation of behavior
0.61	GO:0046883	regulation of hormone secretion
0.59	GO:0008283	cell proliferation
0.59	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
0.56	GO:0045761	regulation of adenylate cyclase activity
0.51	GO:0014062	regulation of serotonin secretion
0.51	GO:0007608	sensory perception of smell

0.82	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.82	GO:0008227	G-protein coupled amine receptor activity
0.63	GO:0099589	serotonin receptor activity
0.51	GO:0090722	receptor-receptor interaction
0.43	GO:0051378	serotonin binding
0.34	GO:0001965	G-protein alpha-subunit binding
0.32	GO:0008144	drug binding

0.57	GO:0005887	integral component of plasma membrane
0.34	GO:0043203	axon hillock
0.33	GO:0005622	intracellular

sp|P22293|SUS_DROME
Protein suppressor of sable
Search

0.74	Protein suppressor of sable

0.67	GO:0071027	nuclear RNA surveillance
0.58	GO:0045892	negative regulation of transcription, DNA-templated
0.37	GO:0071897	DNA biosynthetic process
0.35	GO:0006351	transcription, DNA-templated

0.54	GO:0046872	metal ion binding
0.49	GO:0003723	RNA binding
0.37	GO:0003887	DNA-directed DNA polymerase activity
0.35	GO:0003677	DNA binding
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.67	GO:0035327	transcriptionally active chromatin
0.66	GO:0005700	polytene chromosome
0.57	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0003887

sp|P22464|ANXB9_DROME
Annexin B9
Search

0.67

Annexin

0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression
0.30	GO:0051036	regulation of endosome size
0.30	GO:0048731	system development
0.30	GO:0007163	establishment or maintenance of cell polarity
0.30	GO:0016197	endosomal transport
0.30	GO:0016192	vesicle-mediated transport
0.30	GO:0009953	dorsal/ventral pattern formation
0.30	GO:0060429	epithelium development

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.33	GO:0003700	DNA binding transcription factor activity
0.30	GO:0008092	cytoskeletal protein binding

0.30	GO:0016020	membrane
0.30	GO:0044464	cell part

sp|P22465|ANX10_DROME
Annexin B10
Search

0.64

Annexin

0.35

GO:0006783

heme biosynthetic process

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.36	GO:0004325	ferrochelatase activity
0.34	GO:0003779	actin binding

0.30

GO:0016020

membrane

0.36	EC:4.99.1.1	GO:0004325
0.36	KEGG:R00310	GO:0004325

sp|P22468|GDL_DROME
Gonadal protein gdl
Search

GDL

0.97	DiGeorge syndrome critical region gene 6

sp|P22469|Z600_DROME
Protein Z600
Search

0.87	GO:0007370	ventral furrow formation
0.84	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle
0.82	GO:0045839	negative regulation of mitotic nuclear division
0.43	GO:0051301	cell division
0.43	GO:0007049	cell cycle

0.83

GO:0030332

cyclin binding

0.49	GO:0005737	cytoplasm
0.41	GO:0005634	nucleus

sp|P22700|ATC1_DROME
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type
Search

0.59	Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

0.77	GO:0070588	calcium ion transmembrane transport
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.47	GO:1901896	positive regulation of calcium-transporting ATPase activity
0.46	GO:0007629	flight behavior
0.46	GO:1990845	adaptive thermogenesis
0.46	GO:0036335	intestinal stem cell homeostasis
0.46	GO:0030322	stabilization of membrane potential
0.46	GO:0010884	positive regulation of lipid storage
0.45	GO:0007274	neuromuscular synaptic transmission
0.45	GO:0060047	heart contraction

0.80	GO:0005388	calcium-transporting ATPase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.48	GO:0016529	sarcoplasmic reticulum
0.44	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

0.80

EC:3.6.3.8

GO:0005388

sp|P22711|TIN_DROME
Muscle-specific homeobox protein tinman
Search

0.97	Muscle-specific homeobox protein tinman

0.70	GO:0007507	heart development
0.67	GO:0048615	embryonic anterior midgut (ectodermal) morphogenesis
0.66	GO:0061320	pericardial nephrocyte differentiation
0.66	GO:0007506	gonadal mesoderm development
0.66	GO:0007368	determination of left/right symmetry
0.65	GO:0014706	striated muscle tissue development
0.65	GO:0061101	neuroendocrine cell differentiation
0.65	GO:0051146	striated muscle cell differentiation
0.64	GO:1903779	regulation of cardiac conduction
0.64	GO:0048542	lymph gland development

0.65	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.65	GO:0043565	sequence-specific DNA binding
0.62	GO:0035326	enhancer binding
0.62	GO:0001012	RNA polymerase II regulatory region DNA binding
0.58	GO:0003690	double-stranded DNA binding
0.47	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.47	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.46	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0003682	chromatin binding
0.45	GO:0001104	RNA polymerase II transcription cofactor activity

0.61	GO:0005634	nucleus
0.45	GO:0005667	transcription factor complex
0.44	GO:0032993	protein-DNA complex
0.39	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|P22745|BAM_DROME
Protein bag-of-marbles
Search

BAM

0.97	Bag of marbles

0.87	GO:0098729	germline stem cell symmetric division
0.87	GO:0007284	spermatogonial cell division
0.87	GO:0045478	fusome organization
0.87	GO:0007282	cystoblast division
0.87	GO:0048132	female germ-line stem cell asymmetric division
0.87	GO:0035212	cell competition in a multicellular organism
0.87	GO:0030727	germarium-derived female germ-line cyst formation
0.85	GO:0030718	germ-line stem cell population maintenance
0.77	GO:0017148	negative regulation of translation
0.44	GO:0007140	male meiotic nuclear division

0.86	GO:0000900	translation repressor activity, nucleic acid binding
0.84	GO:0003730	mRNA 3'-UTR binding
0.38	GO:0005515	protein binding

0.87	GO:0045170	spectrosome
0.86	GO:0045169	fusome

sp|P22769|PSA71_DROME
Proteasome subunit alpha type-7-1
Search

0.48	Proteasome endopeptidase complex

0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.36	GO:0010498	proteasomal protein catabolic process
0.35	GO:0008063	Toll signaling pathway
0.35	GO:0007623	circadian rhythm

0.77	GO:0070003	threonine-type peptidase activity
0.65	GO:0004175	endopeptidase activity

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.60	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

sp|P22807|SLOU_DROME
Homeobox protein slou
Search

0.89	Homeobox protein slou

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.42	GO:0007521	muscle cell fate determination
0.42	GO:0007501	mesodermal cell fate specification
0.40	GO:0007517	muscle organ development
0.38	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0051960	regulation of nervous system development

0.65	GO:0043565	sequence-specific DNA binding
0.33	GO:0004000	adenosine deaminase activity

0.61

GO:0005634

nucleus

0.33

GO:0004000

sp|P22808|VND_DROME
Homeobox protein vnd
Search

VND

0.89	Homeobox protein vnd

0.62	GO:0001709	cell fate determination
0.62	GO:0021782	glial cell development
0.62	GO:0014019	neuroblast development
0.61	GO:0014017	neuroblast fate commitment
0.58	GO:0007417	central nervous system development
0.57	GO:0045944	positive regulation of transcription by RNA polymerase II
0.56	GO:0048513	animal organ development
0.56	GO:0060322	head development
0.55	GO:0000122	negative regulation of transcription by RNA polymerase II
0.47	GO:0009953	dorsal/ventral pattern formation

0.64	GO:0043565	sequence-specific DNA binding
0.55	GO:0008134	transcription factor binding
0.52	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.44	GO:0003713	transcription coactivator activity
0.43	GO:0003682	chromatin binding
0.43	GO:0044212	transcription regulatory region DNA binding
0.42	GO:0003690	double-stranded DNA binding
0.33	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

GO:0004000

sp|P22809|BAGP_DROME
Homeobox protein bagpipe
Search

0.82	Homeobox protein bagpipe

0.58	GO:0007498	mesoderm development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0051254	positive regulation of RNA metabolic process
0.53	GO:0010557	positive regulation of macromolecule biosynthetic process
0.53	GO:0031328	positive regulation of cellular biosynthetic process
0.45	GO:0035295	tube development
0.44	GO:0009790	embryo development
0.44	GO:0055123	digestive system development

0.64	GO:0043565	sequence-specific DNA binding
0.59	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.43	GO:0044212	transcription regulatory region DNA binding
0.42	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.42	GO:0003690	double-stranded DNA binding
0.40	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.40	GO:0004882	androgen receptor activity
0.40	GO:0030284	estrogen receptor activity
0.40	GO:0030331	estrogen receptor binding
0.39	GO:0043621	protein self-association

0.61	GO:0005634	nucleus
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

GO:0004000

sp|P22810|HMOC_DROME
Homeotic protein ocelliless
Search

0.76	Homeotic protein ocelliless

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.54	GO:0007275	multicellular organism development
0.45	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.45	GO:0000904	cell morphogenesis involved in differentiation
0.44	GO:0120036	plasma membrane bounded cell projection organization
0.44	GO:0006366	transcription by RNA polymerase II
0.43	GO:0051254	positive regulation of RNA metabolic process
0.43	GO:0010557	positive regulation of macromolecule biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.48	GO:0003700	DNA binding transcription factor activity
0.44	GO:0001012	RNA polymerase II regulatory region DNA binding
0.42	GO:0003690	double-stranded DNA binding
0.35	GO:0046982	protein heterodimerization activity
0.34	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0008190	eukaryotic initiation factor 4E binding
0.34	GO:0042803	protein homodimerization activity

0.61	GO:0005634	nucleus
0.46	GO:0030426	growth cone
0.39	GO:0043234	protein complex
0.32	GO:0005737	cytoplasm

sp|P22812|TUBE_DROME
Protein Tube
Search

0.85	GO:0007526	larval somatic muscle development
0.85	GO:0019732	antifungal humoral response
0.85	GO:0048262	determination of dorsal/ventral asymmetry
0.84	GO:0008063	Toll signaling pathway
0.47	GO:0035172	hemocyte proliferation
0.45	GO:0009950	dorsal/ventral axis specification
0.43	GO:0030097	hemopoiesis
0.43	GO:0045087	innate immune response
0.43	GO:0006915	apoptotic process
0.39	GO:0006468	protein phosphorylation

0.75	GO:0019904	protein domain specific binding
0.41	GO:0004674	protein serine/threonine kinase activity
0.40	GO:0004871	signal transducer activity
0.33	GO:0046982	protein heterodimerization activity

0.67	GO:0005829	cytosol
0.54	GO:0005886	plasma membrane
0.39	GO:0005634	nucleus
0.33	GO:0000428	DNA-directed RNA polymerase complex
0.33	GO:0005667	transcription factor complex
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.41

GO:0004674

sp|P22813|HSF_DROME
Heat shock factor protein
Search

0.74	Heat shock factor-b

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.38	GO:0043388	positive regulation of DNA binding
0.37	GO:0050832	defense response to fungus
0.36	GO:0042742	defense response to bacterium
0.36	GO:0009408	response to heat
0.36	GO:0051254	positive regulation of RNA metabolic process
0.36	GO:0010557	positive regulation of macromolecule biosynthetic process
0.36	GO:0031328	positive regulation of cellular biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.36	GO:0042802	identical protein binding

0.61	GO:0005634	nucleus
0.37	GO:0005700	polytene chromosome
0.36	GO:0000785	chromatin
0.30	GO:0031224	intrinsic component of membrane

sp|P22814|RUNT_DROME
Segmentation protein Runt
Search

RUN

0.84	Segmentation protein Runt

0.60	GO:0007377	germ-band extension
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0048592	eye morphogenesis
0.54	GO:0007411	axon guidance
0.51	GO:1902680	positive regulation of RNA biosynthetic process
0.50	GO:1902679	negative regulation of RNA biosynthetic process
0.39	GO:0007366	periodic partitioning by pair rule gene
0.39	GO:0007540	sex determination, establishment of X:A ratio

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.38	GO:0005779	integral component of peroxisomal membrane

sp|P22815|BOSS_DROME
Protein bride of sevenless
Search

BOSS

0.97	Bride of sevenless

0.78	GO:0007601	visual perception
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.66	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity
0.62	GO:0009749	response to glucose
0.61	GO:0055088	lipid homeostasis
0.61	GO:0050730	regulation of peptidyl-tyrosine phosphorylation
0.60	GO:0042593	glucose homeostasis
0.42	GO:0045470	R8 cell-mediated photoreceptor organization
0.42	GO:0051966	regulation of synaptic transmission, glutamatergic
0.41	GO:0007465	R7 cell fate commitment

0.87	GO:0005118	sevenless binding
0.72	GO:0004930	G-protein coupled receptor activity
0.67	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.40	GO:0008066	glutamate receptor activity

0.65	GO:0031528	microvillus membrane
0.64	GO:0005771	multivesicular body
0.52	GO:0005887	integral component of plasma membrane

sp|P22816|MYOD_DROME
Myogenic-determination protein
Search

0.58	Transcription factor SUM-1

0.81	GO:0007517	muscle organ development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0007526	larval somatic muscle development
0.49	GO:0007267	cell-cell signaling
0.48	GO:1901741	positive regulation of myoblast fusion
0.45	GO:0007518	myoblast fate determination
0.44	GO:0045663	positive regulation of myoblast differentiation
0.44	GO:0043503	skeletal muscle fiber adaptation

0.68	GO:0046983	protein dimerization activity
0.55	GO:0003677	DNA binding
0.45	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.44	GO:0001067	regulatory region nucleic acid binding
0.43	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.42	GO:0035257	nuclear hormone receptor binding
0.41	GO:0031625	ubiquitin protein ligase binding
0.40	GO:0003713	transcription coactivator activity
0.40	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.41	GO:0030016	myofibril
0.40	GO:0005667	transcription factor complex
0.39	GO:0000785	chromatin
0.39	GO:0070013	intracellular organelle lumen
0.39	GO:0005829	cytosol
0.33	GO:0005581	collagen trimer
0.30	GO:0016020	membrane

sp|P22817|IDE_DROME
Insulin-degrading enzyme
Search

IDE

0.44	Insulin-degrading enzyme

0.60	GO:0006508	proteolysis
0.56	GO:1901143	insulin catabolic process
0.55	GO:0090062	regulation of trehalose metabolic process
0.55	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling
0.54	GO:0046662	regulation of oviposition
0.54	GO:0002021	response to dietary excess
0.52	GO:0008340	determination of adult lifespan
0.51	GO:0045926	negative regulation of growth
0.50	GO:0048638	regulation of developmental growth
0.43	GO:1990798	pancreas regeneration

0.69	GO:0004222	metalloendopeptidase activity
0.54	GO:0046872	metal ion binding
0.32	GO:0003735	structural constituent of ribosome

0.41	GO:0005886	plasma membrane
0.38	GO:0005737	cytoplasm
0.33	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.31	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.69

EC:3.4.24

GO:0004222

sp|P22977|CH16_DROME
Chorion protein S16
Search

0.79	GO:0046843	dorsal appendage formation
0.70	GO:0007275	multicellular organism development

0.85	GO:0042600	chorion
0.42	GO:0005576	extracellular region

sp|P22978|HS6B_DROME
Heat shock protein 67B2
Search

0.39	Sulfurtransferase

0.67

GO:0004792

thiosulfate sulfurtransferase activity

0.30

GO:0044425

membrane part

0.67	EC:2.8.1.1	GO:0004792
0.67	KEGG:R01931	GO:0004792

sp|P22979|HSP6C_DROME
Heat shock protein 67B3
Search

HSP27

0.85	Alpha-crystallin B chain

0.80	GO:1903061	positive regulation of protein lipidation
0.75	GO:0009408	response to heat
0.75	GO:0010998	regulation of translational initiation by eIF2 alpha phosphorylation
0.65	GO:0010506	regulation of autophagy
0.62	GO:0061077	chaperone-mediated protein folding
0.58	GO:0042026	protein refolding
0.57	GO:0009631	cold acclimation
0.56	GO:0042595	behavioral response to starvation
0.55	GO:0008340	determination of adult lifespan
0.52	GO:0050832	defense response to fungus

0.57	GO:0051082	unfolded protein binding
0.40	GO:0017022	myosin binding
0.36	GO:0005212	structural constituent of eye lens
0.36	GO:0003779	actin binding

0.73	GO:0030018	Z disc
0.34	GO:0005634	nucleus

sp|P23023|DSX_DROME
Protein doublesex
Search

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.34	GO:0048071	sex-specific pigmentation
0.34	GO:0045496	male analia development
0.34	GO:0045497	female analia development
0.34	GO:0019101	female somatic sex determination
0.34	GO:0048086	negative regulation of developmental pigmentation
0.33	GO:0007486	imaginal disc-derived female genitalia development
0.33	GO:0045498	sex comb development

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0046872	metal ion binding
0.33	GO:0001012	RNA polymerase II regulatory region DNA binding
0.33	GO:0042803	protein homodimerization activity
0.32	GO:0003690	double-stranded DNA binding

0.61

GO:0005634

nucleus

sp|P23128|DDX6_DROME
Putative ATP-dependent RNA helicase me31b
Search

0.39	DEAD box ATP-dependent RNA helicase

0.49	GO:0033962	cytoplasmic mRNA processing body assembly
0.48	GO:0090328	regulation of olfactory learning
0.47	GO:0007279	pole cell formation
0.47	GO:0046959	habituation
0.45	GO:0050688	regulation of defense response to virus
0.45	GO:0030707	ovarian follicle cell development
0.45	GO:0035195	gene silencing by miRNA
0.43	GO:0006413	translational initiation
0.39	GO:0010501	RNA secondary structure unwinding
0.37	GO:0008340	determination of adult lifespan

0.67	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.38	GO:0008186	RNA-dependent ATPase activity
0.35	GO:0140098	catalytic activity, acting on RNA
0.33	GO:0005515	protein binding

0.47	GO:0043186	P granule
0.47	GO:0000932	P-body
0.40	GO:0010494	cytoplasmic stress granule
0.38	GO:1990124	messenger ribonucleoprotein complex
0.37	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

sp|P23226|MA205_DROME
205 kDa microtubule-associated protein
Search

MAP205

0.97	Microtubule-associated protein 205, isoform B

0.81	GO:0007098	centrosome cycle
0.74	GO:0000278	mitotic cell cycle
0.35	GO:0046601	positive regulation of centriole replication
0.35	GO:0007160	cell-matrix adhesion
0.35	GO:1904781	positive regulation of protein localization to centrosome
0.35	GO:1903438	positive regulation of mitotic cytokinetic process
0.35	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.35	GO:0098534	centriole assembly
0.35	GO:0051310	metaphase plate congression
0.35	GO:0045840	positive regulation of mitotic nuclear division

0.53	GO:0008017	microtubule binding
0.35	GO:0051425	PTB domain binding
0.35	GO:0046966	thyroid hormone receptor binding
0.35	GO:0042169	SH2 domain binding
0.35	GO:0051879	Hsp90 protein binding
0.35	GO:0030544	Hsp70 protein binding
0.35	GO:0030159	receptor signaling complex scaffold activity
0.34	GO:0043130	ubiquitin binding
0.34	GO:0017056	structural constituent of nuclear pore
0.34	GO:0005509	calcium ion binding

0.82	GO:0030496	midbody
0.76	GO:0005819	spindle
0.75	GO:0005875	microtubule associated complex
0.53	GO:0005874	microtubule
0.40	GO:0005737	cytoplasm
0.35	GO:0070701	mucus layer
0.35	GO:0044613	nuclear pore central transport channel
0.34	GO:0031965	nuclear membrane
0.34	GO:0005813	centrosome
0.33	GO:0030529	intracellular ribonucleoprotein complex

sp|P23257|TBG1_DROME
Tubulin gamma-1 chain
Search

0.70	Tubulin gamma chain

0.84	GO:0031122	cytoplasmic microtubule organization
0.81	GO:0007020	microtubule nucleation
0.47	GO:0000212	meiotic spindle organization
0.47	GO:0000280	nuclear division
0.47	GO:0007312	oocyte nucleus migration involved in oocyte dorsal/ventral axis specification
0.46	GO:0098813	nuclear chromosome segregation
0.45	GO:0010457	centriole-centriole cohesion
0.43	GO:0051225	spindle assembly
0.42	GO:0051304	chromosome separation
0.42	GO:1903047	mitotic cell cycle process

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0051011	microtubule minus-end binding
0.37	GO:0042802	identical protein binding
0.35	GO:0005200	structural constituent of cytoskeleton

0.84	GO:0000930	gamma-tubulin complex
0.73	GO:0005874	microtubule
0.50	GO:0005813	centrosome
0.50	GO:0005819	spindle
0.39	GO:0036064	ciliary basal body
0.39	GO:0055037	recycling endosome
0.39	GO:0097730	non-motile cilium
0.39	GO:0005814	centriole
0.38	GO:0045177	apical part of cell
0.38	GO:0031252	cell leading edge

sp|P23380|VATL_DROME
V-type proton ATPase 16 kDa proteolipid subunit
Search

0.61	V-type proton ATPase proteolipid subunit

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.45	GO:0033227	dsRNA transport
0.40	GO:0007042	lysosomal lumen acidification
0.40	GO:0030177	positive regulation of Wnt signaling pathway
0.35	GO:0060036	notochord cell vacuolation
0.35	GO:0001878	response to yeast
0.35	GO:0060059	embryonic retina morphogenesis in camera-type eye
0.34	GO:0070588	calcium ion transmembrane transport

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.39	GO:0031625	ubiquitin protein ligase binding
0.38	GO:0036442	proton-exporting ATPase activity
0.37	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.34	GO:0005245	voltage-gated calcium channel activity

0.79	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.76	GO:0005774	vacuolar membrane
0.47	GO:0033181	plasma membrane proton-transporting V-type ATPase complex
0.46	GO:0045169	fusome
0.34	GO:0048786	presynaptic active zone
0.34	GO:0008021	synaptic vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|P23487|MEX1_DROME
Protein midgut expression 1
Search

0.70	Putative conserved protein with signal anchor

0.39

GO:0007275

multicellular organism development

0.30

GO:0044425

membrane part

sp|P23488|OPAP_DROME
Male-specific opa-containing protein
Search

MSOPA

0.92	Male-specific opa containing gene, isoform B

0.43	GO:0006413	translational initiation
0.42	GO:0006950	response to stress
0.41	GO:0032504	multicellular organism reproduction
0.40	GO:0006090	pyruvate metabolic process
0.39	GO:0065009	regulation of molecular function
0.38	GO:0035023	regulation of Rho protein signal transduction
0.38	GO:0051716	cellular response to stimulus
0.38	GO:0007121	bipolar cellular bud site selection
0.37	GO:0007625	grooming behavior
0.37	GO:0051666	actin cortical patch localization

0.44	GO:0003743	translation initiation factor activity
0.43	GO:0004742	dihydrolipoyllysine-residue acetyltransferase activity
0.42	GO:0005525	GTP binding
0.42	GO:0003924	GTPase activity
0.41	GO:0003779	actin binding
0.40	GO:0098772	molecular function regulator
0.39	GO:0003735	structural constituent of ribosome
0.39	GO:0046872	metal ion binding
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0008144	drug binding

0.42	GO:0045254	pyruvate dehydrogenase complex
0.40	GO:0005615	extracellular space
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.38	GO:0070013	intracellular organelle lumen
0.38	GO:0044448	cell cortex part
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.38	GO:0044446	intracellular organelle part
0.37	GO:0000131	incipient cellular bud site
0.37	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0033202	DNA helicase complex

0.43	EC:2.3.1.12	GO:0004742
0.38	KEGG:R00209	GO:0034604

sp|P23572|CDK1_DROME
Cyclin-dependent kinase 1
Search

CDK1

0.50	Eukaryotic translation initiation factor 3 subunit F

0.63	GO:0006468	protein phosphorylation
0.50	GO:0007346	regulation of mitotic cell cycle
0.49	GO:0044772	mitotic cell cycle phase transition
0.48	GO:0051301	cell division
0.47	GO:0031572	G2 DNA damage checkpoint
0.47	GO:0030727	germarium-derived female germ-line cyst formation
0.47	GO:0010948	negative regulation of cell cycle process
0.47	GO:0044839	cell cycle G2/M phase transition
0.46	GO:0140013	meiotic nuclear division
0.46	GO:0007405	neuroblast proliferation

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097472	cyclin-dependent protein kinase activity
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0000993	RNA polymerase II core binding
0.39	GO:0042393	histone binding
0.37	GO:0035173	histone kinase activity
0.37	GO:0030544	Hsp70 protein binding

0.44	GO:0015630	microtubule cytoskeleton
0.44	GO:0044430	cytoskeletal part
0.42	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.41	GO:0005634	nucleus
0.39	GO:0005935	cellular bud neck
0.39	GO:0099512	supramolecular fiber
0.39	GO:0010494	cytoplasmic stress granule
0.37	GO:0005783	endoplasmic reticulum
0.37	GO:0030496	midbody
0.36	GO:0005759	mitochondrial matrix

0.69

GO:0004674

sp|P23573|CDK2_DROME
Cyclin-dependent kinase 2
Search

CDK2

0.49	Cell division protein kinase

0.63	GO:0006468	protein phosphorylation
0.48	GO:0046427	positive regulation of JAK-STAT cascade
0.46	GO:0051726	regulation of cell cycle
0.45	GO:0044772	mitotic cell cycle phase transition
0.45	GO:0051301	cell division
0.44	GO:2000105	positive regulation of DNA-dependent DNA replication
0.44	GO:0044843	cell cycle G1/S phase transition
0.43	GO:0000226	microtubule cytoskeleton organization
0.42	GO:2000241	regulation of reproductive process
0.42	GO:0008284	positive regulation of cell proliferation

0.67	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.50	GO:0097472	cyclin-dependent protein kinase activity
0.42	GO:0030332	cyclin binding
0.41	GO:0035173	histone kinase activity
0.39	GO:0019904	protein domain specific binding
0.38	GO:0000993	RNA polymerase II core binding

0.45	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.43	GO:0000806	Y chromosome
0.43	GO:0015630	microtubule cytoskeleton
0.42	GO:0044430	cytoskeletal part
0.42	GO:0000805	X chromosome
0.41	GO:0015030	Cajal body
0.40	GO:0000781	chromosome, telomeric region
0.39	GO:0000793	condensed chromosome
0.39	GO:0005768	endosome
0.39	GO:0005667	transcription factor complex

0.67

GO:0004674

sp|P23625|GNAQ_DROME
G protein alpha q subunit
Search

0.74	Heterotrimeric GTP-binding protein alpha subunit G-alpha-q

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.40	GO:0007603	phototransduction, visible light
0.39	GO:0035690	cellular response to drug
0.39	GO:0009649	entrainment of circadian clock
0.38	GO:1903831	signal transduction involved in cellular response to ammonium ion
0.38	GO:1905144	response to acetylcholine
0.38	GO:0051345	positive regulation of hydrolase activity
0.38	GO:1901701	cellular response to oxygen-containing compound
0.38	GO:0042391	regulation of membrane potential
0.37	GO:0019933	cAMP-mediated signaling

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.80	GO:0001664	G-protein coupled receptor binding
0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.64	GO:0004871	signal transducer activity
0.37	GO:0005096	GTPase activator activity
0.33	GO:0046872	metal ion binding
0.33	GO:0016874	ligase activity

0.40	GO:1905360	GTPase complex
0.40	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.38	GO:0001750	photoreceptor outer segment
0.37	GO:0098797	plasma membrane protein complex
0.35	GO:0031965	nuclear membrane
0.35	GO:0016028	rhabdomere
0.34	GO:0005765	lysosomal membrane
0.34	GO:0070062	extracellular exosome
0.34	GO:0030425	dendrite
0.34	GO:0044297	cell body

0.33

GO:0016874

sp|P23645|BIB_DROME
Neurogenic protein big brain
Search

BIB

0.83	Neurogenic protein big brain

0.55	GO:0055085	transmembrane transport
0.40	GO:0046331	lateral inhibition
0.39	GO:0044719	regulation of imaginal disc-derived wing size
0.39	GO:0007398	ectoderm development
0.38	GO:0030707	ovarian follicle cell development
0.38	GO:0007498	mesoderm development
0.38	GO:0007219	Notch signaling pathway
0.37	GO:0098609	cell-cell adhesion
0.37	GO:0007399	nervous system development
0.36	GO:0007084	mitotic nuclear envelope reassembly

0.69	GO:0015267	channel activity
0.40	GO:0005372	water transmembrane transporter activity
0.36	GO:0051721	protein phosphatase 2A binding
0.35	GO:0008324	cation transmembrane transporter activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005912	adherens junction
0.37	GO:0031410	cytoplasmic vesicle
0.37	GO:0005887	integral component of plasma membrane
0.32	GO:0005634	nucleus

sp|P23647|FUSED_DROME
Serine/threonine-protein kinase fused
Search

0.51	Serine-threonine kinase Fused

0.63	GO:0006468	protein phosphorylation
0.58	GO:0007228	positive regulation of hh target transcription factor activity
0.57	GO:0007367	segment polarity determination
0.56	GO:0007293	germarium-derived egg chamber formation
0.55	GO:0030514	negative regulation of BMP signaling pathway
0.54	GO:0042073	intraciliary transport
0.53	GO:0031398	positive regulation of protein ubiquitination
0.52	GO:0031647	regulation of protein stability
0.36	GO:0030162	regulation of proteolysis
0.34	GO:0060271	cilium assembly

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding

0.58	GO:0035301	Hedgehog signaling complex
0.51	GO:0005929	cilium
0.36	GO:0005829	cytosol
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

GO:0016705

sp|P23654|NRT_DROME
Neurotactin
Search

0.30	Carboxylesterase

0.63	GO:0007413	axonal fasciculation
0.59	GO:0007411	axon guidance
0.57	GO:0007417	central nervous system development
0.37	GO:0007155	cell adhesion
0.34	GO:0005975	carbohydrate metabolic process
0.32	GO:0001507	acetylcholine catabolic process in synaptic cleft

0.40	GO:0052689	carboxylic ester hydrolase activity
0.35	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.59	GO:0016323	basolateral plasma membrane
0.33	GO:0005737	cytoplasm
0.32	GO:0043083	synaptic cleft
0.30	GO:0016021	integral component of membrane

0.40	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.40	KEGG:R00630	GO:0052689

sp|P23696|PP2A_DROME
Serine/threonine-protein phosphatase PP2A
Search

0.50	Serine/threonine-protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.52	GO:0045596	negative regulation of cell differentiation
0.51	GO:0051241	negative regulation of multicellular organismal process
0.50	GO:0009888	tissue development
0.50	GO:0010717	regulation of epithelial to mesenchymal transition
0.49	GO:0001932	regulation of protein phosphorylation
0.48	GO:0033674	positive regulation of kinase activity
0.47	GO:0031401	positive regulation of protein modification process
0.46	GO:0007465	R7 cell fate commitment
0.45	GO:0055059	asymmetric neuroblast division

0.72	GO:0004721	phosphoprotein phosphatase activity
0.52	GO:0050811	GABA receptor binding
0.50	GO:0008022	protein C-terminus binding
0.47	GO:0046982	protein heterodimerization activity
0.43	GO:0019208	phosphatase regulator activity
0.35	GO:0046872	metal ion binding
0.35	GO:1990405	protein antigen binding
0.35	GO:0031698	beta-2 adrenergic receptor binding
0.35	GO:0048156	tau protein binding
0.35	GO:0043422	protein kinase B binding

0.51	GO:0000159	protein phosphatase type 2A complex
0.47	GO:0000775	chromosome, centromeric region
0.45	GO:0005829	cytosol
0.44	GO:0005814	centriole
0.40	GO:0005886	plasma membrane
0.39	GO:0000922	spindle pole
0.36	GO:0005634	nucleus
0.36	GO:0033267	axon part
0.36	GO:0070062	extracellular exosome
0.34	GO:0043679	axon terminus

0.72

GO:0004721

sp|P23757|POXM_DROME
Paired box pox-meso protein
Search

0.73	Paired box protein Pax-9

0.70	GO:0007275	multicellular organism development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0009653	anatomical structure morphogenesis
0.52	GO:0007525	somatic muscle development
0.51	GO:0030154	cell differentiation
0.50	GO:0036037	CD8-positive, alpha-beta T cell activation
0.50	GO:0016358	dendrite development

0.59	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.45	GO:0001067	regulatory region nucleic acid binding

0.61	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|P23758|POXN_DROME
Paired box pox-neuro protein
Search

0.91	Paired box pox-neuro protein (Fragment)

0.69	GO:0007275	multicellular organism development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0008343	adult feeding behavior
0.54	GO:0008049	male courtship behavior
0.51	GO:0009415	response to water
0.50	GO:0002009	morphogenesis of an epithelium
0.37	GO:0030154	cell differentiation

0.55	GO:0003677	DNA binding
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0005515	protein binding
0.32	GO:0016301	kinase activity

0.61	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P23779|CYTL_DROME
Cystatin-like protein
Search

0.76	GO:0010951	negative regulation of endopeptidase activity
0.40	GO:0032504	multicellular organism reproduction
0.40	GO:0006508	proteolysis

0.83	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.43	GO:0008234	cysteine-type peptidase activity

0.39	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.43

GO:0008234

sp|P23792|DISC_DROME
Protein disconnected
Search

0.85	Protein disconnected

0.56	GO:0008062	eclosion rhythm
0.55	GO:0007479	leg disc proximal/distal pattern formation
0.54	GO:0007469	antennal development
0.53	GO:0045475	locomotor rhythm
0.49	GO:0007420	brain development
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II
0.43	GO:0048526	imaginal disc-derived wing expansion
0.42	GO:0060232	delamination
0.41	GO:0001837	epithelial to mesenchymal transition
0.40	GO:0045494	photoreceptor cell maintenance

0.52	GO:0001158	enhancer sequence-specific DNA binding
0.36	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding

0.42	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P23803|ODD_DROME
Protein odd-skipped
Search

0.93	Protein odd-skipped

0.56	GO:0007366	periodic partitioning by pair rule gene
0.56	GO:0016348	imaginal disc-derived leg joint morphogenesis
0.54	GO:0007443	Malpighian tubule morphogenesis
0.49	GO:0000122	negative regulation of transcription by RNA polymerase II
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.35	GO:0003700	DNA binding transcription factor activity
0.34	GO:0046872	metal ion binding

0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P23938|NG1_DROME
Protein new-glue 1
Search

0.41	GO:0030245	cellulose catabolic process
0.41	GO:0007264	small GTPase mediated signal transduction
0.39	GO:0016573	histone acetylation
0.39	GO:0006367	transcription initiation from RNA polymerase II promoter
0.38	GO:0065009	regulation of molecular function
0.38	GO:0016204	determination of muscle attachment site
0.38	GO:0007526	larval somatic muscle development
0.37	GO:0071555	cell wall organization
0.37	GO:0006508	proteolysis
0.36	GO:0034765	regulation of ion transmembrane transport

0.45	GO:0030248	cellulose binding
0.42	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.40	GO:0005085	guanyl-nucleotide exchange factor activity
0.39	GO:0004402	histone acetyltransferase activity
0.38	GO:0003712	transcription cofactor activity
0.37	GO:0008270	zinc ion binding
0.37	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.37	GO:0045330	aspartyl esterase activity
0.37	GO:0030599	pectinesterase activity
0.37	GO:0005245	voltage-gated calcium channel activity

0.49	GO:0005576	extracellular region
0.39	GO:0005672	transcription factor TFIIA complex
0.38	GO:0005618	cell wall
0.37	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.37	GO:0009897	external side of plasma membrane
0.37	GO:0005891	voltage-gated calcium channel complex
0.36	GO:0031982	vesicle

0.42

GO:0004553

sp|P24014|SLIT_DROME
Protein slit
Search

0.77	LOW QUALITY PROTEIN: protein slit

0.61	GO:0050929	induction of negative chemotaxis
0.60	GO:0007502	digestive tract mesoderm development
0.59	GO:0007432	salivary gland boundary specification
0.59	GO:2000274	regulation of epithelial cell migration, open tracheal system
0.59	GO:0007509	mesoderm migration involved in gastrulation
0.58	GO:0007427	epithelial cell migration, open tracheal system
0.58	GO:0016199	axon midline choice point recognition
0.57	GO:0035385	Roundabout signaling pathway
0.56	GO:0008347	glial cell migration
0.56	GO:0003151	outflow tract morphogenesis

0.70	GO:0005509	calcium ion binding
0.59	GO:0048495	Roundabout binding
0.54	GO:0008201	heparin binding
0.35	GO:0005549	odorant binding
0.32	GO:0004714	transmembrane receptor protein tyrosine kinase activity

0.61	GO:0071666	Slit-Robo signaling complex
0.60	GO:0005576	extracellular region
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.32

GO:0004714

sp|P24156|L2CC_DROME
Protein l(2)37Cc
Search

0.46	Prohibitin protein WPH

0.44	GO:0071456	cellular response to hypoxia
0.43	GO:0045917	positive regulation of complement activation
0.42	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway
0.42	GO:0050847	progesterone receptor signaling pathway
0.42	GO:0010944	negative regulation of transcription by competitive promoter binding
0.42	GO:0060766	negative regulation of androgen receptor signaling pathway
0.42	GO:0071354	cellular response to interleukin-6
0.42	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
0.41	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.41	GO:0042177	negative regulation of protein catabolic process

0.43	GO:0001850	complement component C3a binding
0.43	GO:0001851	complement component C3b binding
0.43	GO:0031871	proteinase activated receptor binding
0.41	GO:0042826	histone deacetylase binding
0.41	GO:0008022	protein C-terminus binding
0.39	GO:0044212	transcription regulatory region DNA binding
0.39	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.32	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.31	GO:0030554	adenyl nucleotide binding
0.31	GO:0097367	carbohydrate derivative binding

0.40	GO:0043209	myelin sheath
0.40	GO:0009986	cell surface
0.40	GO:0005769	early endosome
0.38	GO:0005654	nucleoplasm
0.37	GO:0005887	integral component of plasma membrane
0.37	GO:0005739	mitochondrion
0.37	GO:0019866	organelle inner membrane
0.35	GO:0031312	extrinsic component of organelle membrane
0.35	GO:0031968	organelle outer membrane
0.34	GO:0070062	extracellular exosome

0.32

GO:0004714

sp|P24350|IPOU_DROME
Inhibitory POU protein
Search

0.54	Abnormal chemosensory jump 6

0.57	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0007636	chemosensory jump behavior
0.48	GO:0070983	dendrite guidance
0.48	GO:0008039	synaptic target recognition
0.45	GO:0007411	axon guidance
0.44	GO:0007600	sensory perception
0.44	GO:0051254	positive regulation of RNA metabolic process

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.46	GO:0003714	transcription corepressor activity
0.36	GO:0035326	enhancer binding
0.36	GO:0003713	transcription coactivator activity
0.35	GO:0003697	single-stranded DNA binding
0.35	GO:0001012	RNA polymerase II regulatory region DNA binding
0.35	GO:0003682	chromatin binding
0.35	GO:0051020	GTPase binding
0.35	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.35	GO:0043005	neuron projection
0.35	GO:0000785	chromatin
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P24492|DIP_DROME
Diptericin
Search

0.97	Antimicrobial peptide diptericin

0.78	GO:0042742	defense response to bacterium
0.76	GO:0006959	humoral immune response
0.74	GO:0055093	response to hyperoxia
0.44	GO:0045087	innate immune response
0.41	GO:0045089	positive regulation of innate immune response

0.55

GO:0005576

extracellular region

sp|P24785|MLE_DROME
Dosage compensation regulator
Search

MLE

0.93	Dosage compensation regulator

0.55	GO:0045433	male courtship behavior, veined wing generated song production
0.54	GO:0031453	positive regulation of heterochromatin assembly
0.53	GO:0007549	dosage compensation
0.52	GO:0048675	axon extension
0.52	GO:0008340	determination of adult lifespan
0.51	GO:0045944	positive regulation of transcription by RNA polymerase II
0.47	GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity
0.47	GO:1905698	positive regulation of polysome binding
0.46	GO:0046833	positive regulation of RNA export from nucleus
0.46	GO:1904973	positive regulation of viral translation

0.67	GO:0004386	helicase activity
0.60	GO:0001069	regulatory region RNA binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0003682	chromatin binding
0.47	GO:1905172	RISC complex binding
0.47	GO:1905538	polysome binding
0.46	GO:0045142	triplex DNA binding

0.54	GO:0000805	X chromosome
0.52	GO:0072487	MSL complex
0.52	GO:0005700	polytene chromosome
0.50	GO:0000228	nuclear chromosome
0.50	GO:0005665	DNA-directed RNA polymerase II, core complex
0.50	GO:0000785	chromatin
0.46	GO:0097165	nuclear stress granule
0.46	GO:0070937	CRD-mediated mRNA stability complex
0.46	GO:0070578	RISC-loading complex
0.45	GO:0035068	micro-ribonucleoprotein complex

0.42

EC:3.6.1.19

GO:0047429

sp|P25007|PPIA_DROME
Peptidyl-prolyl cis-trans isomerase
Search

0.49	Peptidyl-prolyl cis-trans isomerase

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.69	GO:0006457	protein folding
0.37	GO:0010759	positive regulation of macrophage chemotaxis
0.37	GO:0050918	positive chemotaxis
0.36	GO:0060326	cell chemotaxis
0.36	GO:0009704	de-etiolation
0.36	GO:0045836	positive regulation of meiotic nuclear division
0.36	GO:0009585	red, far-red light phototransduction
0.36	GO:0009742	brassinosteroid mediated signaling pathway
0.36	GO:0009735	response to cytokinin

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.37	GO:0042056	chemoattractant activity
0.37	GO:0008009	chemokine activity
0.36	GO:0016018	cyclosporin A binding
0.32	GO:0016301	kinase activity

0.36	GO:0005829	cytosol
0.36	GO:0034967	Set3 complex
0.35	GO:0048046	apoplast
0.35	GO:0005758	mitochondrial intermembrane space
0.35	GO:0030445	yeast-form cell wall
0.35	GO:0097311	biofilm matrix
0.34	GO:0005886	plasma membrane

0.72

EC:5.2.1.8

GO:0003755

sp|P25008|CCNC_DROME
Cyclin-C
Search

0.90	CDK8 kinase-activating protein cyclin C

0.76	GO:0045859	regulation of protein kinase activity
0.48	GO:0045498	sex comb development
0.47	GO:0036011	imaginal disc-derived leg segmentation
0.46	GO:0022416	chaeta development
0.46	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain
0.45	GO:0034472	snRNA 3'-end processing
0.44	GO:0045787	positive regulation of cell cycle
0.43	GO:0033674	positive regulation of kinase activity
0.42	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0072015	glomerular visceral epithelial cell development

0.82	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.44	GO:0001104	RNA polymerase II transcription cofactor activity
0.39	GO:0016301	kinase activity
0.34	GO:0004605	phosphatidate cytidylyltransferase activity
0.34	GO:0005515	protein binding
0.34	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.77	GO:0016592	mediator complex
0.45	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.34	GO:0000151	ubiquitin ligase complex

0.82

GO:0016538

sp|P25028|FSYA_DROME
Mitosis initiation protein fs(1)Ya
Search

0.95	Mitosis initiation protein fs(1)Ya

0.87	GO:0007344	pronuclear fusion
0.76	GO:0006333	chromatin assembly or disassembly
0.74	GO:0030261	chromosome condensation
0.73	GO:0000278	mitotic cell cycle
0.64	GO:0006260	DNA replication
0.52	GO:0042078	germ-line stem cell division
0.52	GO:0030718	germ-line stem cell population maintenance
0.50	GO:0048477	oogenesis
0.40	GO:0005977	glycogen metabolic process
0.36	GO:0016310	phosphorylation

0.45	GO:0005515	protein binding
0.37	GO:0016301	kinase activity
0.36	GO:0003676	nucleic acid binding

0.85	GO:0005652	nuclear lamina
0.74	GO:0005635	nuclear envelope
0.54	GO:0070725	Yb body
0.48	GO:0005737	cytoplasm
0.47	GO:0005654	nucleoplasm
0.36	GO:0005886	plasma membrane

sp|P25123|GBRB_DROME
Gamma-aminobutyric acid receptor subunit beta
Search

0.80	Gamma-aminobutyric acid receptor subunit beta

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.40	GO:0006821	chloride transport
0.39	GO:0090328	regulation of olfactory learning
0.39	GO:0002121	inter-male aggressive behavior
0.39	GO:0030431	sleep
0.39	GO:0042749	regulation of circadian sleep/wake cycle
0.39	GO:0050805	negative regulation of synaptic transmission
0.38	GO:0009612	response to mechanical stimulus
0.36	GO:0042493	response to drug

0.84	GO:0004890	GABA-A receptor activity
0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.40	GO:0005254	chloride channel activity
0.40	GO:0030594	neurotransmitter receptor activity
0.39	GO:0099095	ligand-gated anion channel activity

0.56	GO:0005886	plasma membrane
0.41	GO:0034707	chloride channel complex
0.40	GO:0098794	postsynapse
0.39	GO:0030054	cell junction
0.38	GO:0030425	dendrite
0.38	GO:0030424	axon

sp|P25153|UBCD6_DROME
Ubiquitin-conjugating enzyme E2-17 kDa
Search

0.48	Ubiquitin conjugating enzyme

0.47	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.46	GO:0016567	protein ubiquitination
0.46	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.45	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
0.45	GO:0051299	centrosome separation
0.44	GO:0000422	autophagy of mitochondrion
0.44	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.44	GO:0032456	endocytic recycling
0.43	GO:0006281	DNA repair
0.43	GO:0016570	histone modification

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0031625	ubiquitin protein ligase binding
0.44	GO:0002039	p53 binding
0.43	GO:0004842	ubiquitin-protein transferase activity
0.43	GO:0061650	ubiquitin-like protein conjugating enzyme activity
0.43	GO:0061659	ubiquitin-like protein ligase activity
0.42	GO:0019904	protein domain specific binding
0.39	GO:0016874	ligase activity

0.48	GO:0033503	HULC complex
0.43	GO:0000790	nuclear chromatin
0.43	GO:0001741	XY body
0.37	GO:0005737	cytoplasm
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.39	EC:6	GO:0016874
0.43	KEGG:R03876	GO:0004842

sp|P25157|GNAL_DROME
Guanine nucleotide-binding protein subunit alpha homolog
Search

0.59	Guanine nucleotide-binding protein subunit alpha

0.75	GO:0007264	small GTPase mediated signal transduction
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.49	GO:0002009	morphogenesis of an epithelium
0.48	GO:0009790	embryo development
0.47	GO:0003371	establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration
0.46	GO:0048383	mesectoderm development
0.46	GO:0030154	cell differentiation
0.46	GO:0019933	cAMP-mediated signaling
0.46	GO:0043519	regulation of myosin II filament organization
0.45	GO:0030168	platelet activation

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.79	GO:0001664	G-protein coupled receptor binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046872	metal ion binding
0.34	GO:0045296	cadherin binding

0.44	GO:0005622	intracellular
0.44	GO:0031526	brush border membrane
0.43	GO:1905360	GTPase complex
0.42	GO:0019897	extrinsic component of plasma membrane
0.42	GO:0009898	cytoplasmic side of plasma membrane
0.39	GO:0098797	plasma membrane protein complex
0.35	GO:0005925	focal adhesion
0.35	GO:0031982	vesicle
0.35	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space

sp|P25158|OSKA_DROME
Maternal effect protein oskar
Search

0.85	Maternal effect protein oskar

0.89	GO:0007359	posterior abdomen determination
0.87	GO:0030719	P granule organization
0.87	GO:0008103	oocyte microtubule cytoskeleton polarization
0.86	GO:0040040	thermosensory behavior
0.85	GO:0008542	visual learning
0.84	GO:0043488	regulation of mRNA stability
0.55	GO:0007318	pole plasm protein localization
0.55	GO:0046011	regulation of oskar mRNA translation
0.55	GO:0007279	pole cell formation
0.54	GO:0019094	pole plasm mRNA localization

0.76

GO:0003729

mRNA binding

0.85	GO:0043186	P granule
0.76	GO:0005938	cell cortex

sp|P25159|STAU_DROME
Maternal effect protein staufen
Search

LOC108093935

0.86	Maternal effect protein staufen

0.66	GO:0007318	pole plasm protein localization
0.65	GO:0007317	regulation of pole plasm oskar mRNA localization
0.64	GO:0007316	pole plasm RNA localization
0.64	GO:0045887	positive regulation of synaptic growth at neuromuscular junction
0.64	GO:0035418	protein localization to synapse
0.63	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression
0.30	GO:0072089	stem cell proliferation

0.61	GO:0003730	mRNA 3'-UTR binding
0.32	GO:0003700	DNA binding transcription factor activity
0.31	GO:0003677	DNA binding
0.30	GO:0003725	double-stranded RNA binding
0.30	GO:0008017	microtubule binding

0.66	GO:0071212	subsynaptic reticulum
0.65	GO:0045180	basal cortex
0.63	GO:0045179	apical cortex
0.63	GO:0009925	basal plasma membrane
0.62	GO:0060293	germ plasm
0.60	GO:0016324	apical plasma membrane
0.59	GO:0000932	P-body
0.30	GO:0044422	organelle part
0.30	GO:0015630	microtubule cytoskeleton
0.30	GO:0043234	protein complex

sp|P25160|ARL1_DROME
ADP-ribosylation factor-like protein 1
Search

0.55	ADP ribosylation factor

0.50	GO:0034067	protein localization to Golgi apparatus
0.48	GO:0007030	Golgi organization
0.46	GO:0031584	activation of phospholipase D activity
0.46	GO:0090158	endoplasmic reticulum membrane organization
0.46	GO:0060628	regulation of ER to Golgi vesicle-mediated transport
0.46	GO:0070861	regulation of protein exit from endoplasmic reticulum
0.46	GO:0033363	secretory granule organization
0.45	GO:0033227	dsRNA transport
0.45	GO:0007431	salivary gland development
0.44	GO:0035220	wing disc development

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0019904	protein domain specific binding
0.42	GO:0008047	enzyme activator activity
0.40	GO:0003924	GTPase activity
0.38	GO:0046872	metal ion binding

0.48	GO:0005802	trans-Golgi network
0.40	GO:0005829	cytosol
0.35	GO:0000139	Golgi membrane
0.34	GO:0098793	presynapse
0.34	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P25161|PSMD3_DROME
Probable 26S proteasome non-ATPase regulatory subunit 3
Search

0.66	26S proteasome non-ATPase regulatory subunit

0.77	GO:0042176	regulation of protein catabolic process
0.69	GO:0050790	regulation of catalytic activity
0.39	GO:0006511	ubiquitin-dependent protein catabolic process
0.35	GO:0008063	Toll signaling pathway
0.35	GO:0007623	circadian rhythm
0.34	GO:0010498	proteasomal protein catabolic process

0.70	GO:0030234	enzyme regulator activity
0.41	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding

0.72	GO:1905369	endopeptidase complex
0.59	GO:0043234	protein complex
0.45	GO:0044424	intracellular part
0.34	GO:0043233	organelle lumen
0.33	GO:0043227	membrane-bounded organelle

sp|P25162|ACH4_DROME
Acetylcholine receptor subunit beta-like 2
Search

0.89	Nicotinic acetylcholine receptor alpha subunit

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.49	GO:0017085	response to insecticide
0.48	GO:0007271	synaptic transmission, cholinergic
0.33	GO:0006468	protein phosphorylation

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.78	GO:0045211	postsynaptic membrane
0.73	GO:0030054	cell junction
0.36	GO:0005892	acetylcholine-gated channel complex

sp|P25167|RPC2_DROME
DNA-directed RNA polymerase III subunit RPC2
Search

0.41	DNA-directed RNA polymerase subunit beta

0.58	GO:0006351	transcription, DNA-templated
0.45	GO:0032728	positive regulation of interferon-beta production
0.43	GO:0045089	positive regulation of innate immune response
0.38	GO:0031017	exocrine pancreas development
0.37	GO:0048565	digestive tract development
0.36	GO:0034660	ncRNA metabolic process
0.33	GO:0001510	RNA methylation
0.33	GO:0042254	ribosome biogenesis
0.33	GO:0006396	RNA processing

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.65	GO:0001882	nucleoside binding
0.55	GO:0003677	DNA binding
0.34	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity
0.33	GO:0003723	RNA binding
0.32	GO:0046872	metal ion binding

0.47

GO:0005666

DNA-directed RNA polymerase III complex

0.70

GO:0003899

sp|P25171|RCC1_DROME
Regulator of chromosome condensation
Search

0.78	Putative alpha-tubulin suppressor

0.70	GO:0051290	protein heterotetramerization
0.69	GO:0007346	regulation of mitotic cell cycle
0.67	GO:0000082	G1/S transition of mitotic cell cycle
0.66	GO:0007052	mitotic spindle organization
0.66	GO:0051225	spindle assembly
0.63	GO:0051783	regulation of nuclear division
0.61	GO:0010564	regulation of cell cycle process
0.59	GO:0007059	chromosome segregation
0.58	GO:0006607	NLS-bearing protein import into nucleus
0.56	GO:0065009	regulation of molecular function

0.74	GO:0043199	sulfate binding
0.71	GO:0005087	Ran guanyl-nucleotide exchange factor activity
0.70	GO:0003682	chromatin binding
0.64	GO:0042393	histone binding
0.60	GO:0046982	protein heterodimerization activity
0.59	GO:0044877	macromolecular complex binding
0.47	GO:0003677	DNA binding
0.40	GO:0008157	protein phosphatase 1 binding
0.39	GO:0003735	structural constituent of ribosome
0.39	GO:0019888	protein phosphatase regulator activity

0.69	GO:0000793	condensed chromosome
0.67	GO:0031965	nuclear membrane
0.61	GO:0000790	nuclear chromatin
0.59	GO:0005654	nucleoplasm
0.50	GO:0043234	protein complex
0.44	GO:0005737	cytoplasm
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016021	integral component of membrane

sp|P25172|SUZ2_DROME
Protein suppressor 2 of zeste
Search

0.56	GO:0031062	positive regulation of histone methylation
0.53	GO:0006342	chromatin silencing
0.40	GO:0007275	multicellular organism development
0.32	GO:0016925	protein sumoylation
0.32	GO:0055114	oxidation-reduction process
0.31	GO:0055085	transmembrane transport

0.54	GO:0046872	metal ion binding
0.41	GO:0003677	DNA binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.32	GO:0019789	SUMO transferase activity
0.32	GO:0003682	chromatin binding
0.31	GO:0003700	DNA binding transcription factor activity

0.56	GO:0035102	PRC1 complex
0.47	GO:0005725	intercalary heterochromatin
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0032440

sp|P25228|RAB3_DROME
Ras-related protein Rab-3
Search

0.73	Synaptic vesicle-associated GTP-binding protein (Fragment)

0.45	GO:0048790	maintenance of presynaptic active zone structure
0.45	GO:0048789	cytoskeletal matrix organization at active zone
0.42	GO:0017157	regulation of exocytosis
0.40	GO:0019882	antigen processing and presentation
0.39	GO:0016192	vesicle-mediated transport
0.36	GO:0051588	regulation of neurotransmitter transport
0.36	GO:0050804	modulation of chemical synaptic transmission
0.35	GO:0032482	Rab protein signal transduction
0.35	GO:0065008	regulation of biological quality
0.35	GO:0060341	regulation of cellular localization

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0031489	myosin V binding
0.43	GO:0030742	GTP-dependent protein binding
0.35	GO:0004767	sphingomyelin phosphodiesterase activity
0.34	GO:0008168	methyltransferase activity
0.33	GO:0004871	signal transducer activity

0.46	GO:0008021	synaptic vesicle
0.42	GO:0048786	presynaptic active zone
0.41	GO:0048471	perinuclear region of cytoplasm
0.34	GO:1905360	GTPase complex
0.34	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.34	GO:0030054	cell junction
0.34	GO:0030141	secretory granule
0.33	GO:0005829	cytosol
0.33	GO:0098797	plasma membrane protein complex

0.35	EC:3.1.4.12	GO:0004767
0.35	KEGG:R02541	GO:0004767

sp|P25439|BRM_DROME
ATP-dependent helicase brm
Search

0.35	ATP-dependent helicase brm

0.78	GO:0006338	chromatin remodeling
0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.39	GO:0043974	histone H3-K27 acetylation
0.38	GO:0035172	hemocyte proliferation
0.38	GO:0070983	dendrite guidance
0.38	GO:0043697	cell dedifferentiation
0.38	GO:0036335	intestinal stem cell homeostasis
0.38	GO:0007419	ventral cord development

0.79	GO:0042393	histone binding
0.61	GO:0016887	ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0004386	helicase activity
0.36	GO:0003677	DNA binding
0.32	GO:0016740	transferase activity

0.82	GO:0016514	SWI/SNF complex
0.38	GO:0035060	brahma complex
0.37	GO:0016586	RSC-type complex
0.30	GO:0016021	integral component of membrane

0.61