Queries 6001 to 7000

GO:0004702

sp|P27106|MIS_MOUSE
Muellerian-inhibiting factor
Search

AMH

0.87	Muellerian-inhibiting factor

0.83	GO:0008406	gonad development
0.78	GO:0001880	Mullerian duct regression
0.76	GO:0010469	regulation of receptor activity
0.67	GO:0007498	mesoderm development
0.66	GO:0060485	mesenchyme development
0.65	GO:0001655	urogenital system development
0.60	GO:0007267	cell-cell signaling
0.59	GO:2000355	negative regulation of ovarian follicle development
0.59	GO:0048162	multi-layer follicle stage
0.56	GO:0010628	positive regulation of gene expression

0.78	GO:0008083	growth factor activity
0.63	GO:0005179	hormone activity
0.62	GO:0005160	transforming growth factor beta receptor binding
0.34	GO:0008270	zinc ion binding
0.33	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.39	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus

sp|P27467|WNT3A_MOUSE
Protein Wnt-3a
Search

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.61	GO:0007498	mesoderm development
0.60	GO:0060322	head development
0.60	GO:0050922	negative regulation of chemotaxis
0.59	GO:0072089	stem cell proliferation
0.59	GO:0001649	osteoblast differentiation
0.59	GO:0010771	negative regulation of cell morphogenesis involved in differentiation
0.58	GO:0061387	regulation of extent of cell growth
0.58	GO:0048640	negative regulation of developmental growth

0.73	GO:0005102	receptor binding
0.54	GO:0019904	protein domain specific binding
0.54	GO:0030545	receptor regulator activity
0.52	GO:0039706	co-receptor binding
0.48	GO:0003713	transcription coactivator activity

0.76	GO:0005578	proteinaceous extracellular matrix
0.53	GO:1990851	Wnt-Frizzled-LRP5/6 complex
0.50	GO:0005615	extracellular space
0.47	GO:0009986	cell surface
0.38	GO:0005788	endoplasmic reticulum lumen
0.37	GO:1990909	Wnt signalosome
0.37	GO:0005796	Golgi lumen
0.37	GO:0098805	whole membrane
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0030139	endocytic vesicle

sp|P27512|TNR5_MOUSE
Tumor necrosis factor receptor superfamily member 5
Search

CD40

0.97	Tumor necrosis factor receptor superfamily member 5

0.84	GO:0042113	B cell activation
0.72	GO:0050776	regulation of immune response
0.66	GO:0090037	positive regulation of protein kinase C signaling
0.65	GO:2000353	positive regulation of endothelial cell apoptotic process
0.65	GO:0051023	regulation of immunoglobulin secretion
0.64	GO:0042832	defense response to protozoan
0.64	GO:0032735	positive regulation of interleukin-12 production
0.64	GO:0043491	protein kinase B signaling
0.64	GO:0002639	positive regulation of immunoglobulin production
0.63	GO:0030890	positive regulation of B cell proliferation

0.65	GO:0004872	receptor activity
0.59	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0003823	antigen binding
0.44	GO:0004871	signal transducer activity
0.43	GO:0019904	protein domain specific binding

0.81	GO:0009897	external side of plasma membrane
0.65	GO:0035631	CD40 receptor complex
0.48	GO:0043196	varicosity
0.45	GO:0043231	intracellular membrane-bounded organelle
0.45	GO:0043025	neuronal cell body
0.42	GO:0005615	extracellular space
0.41	GO:1903561	extracellular vesicle
0.36	GO:0005737	cytoplasm

sp|P27545|CERS1_MOUSE
Ceramide synthase 1
Search

CERS1

0.96	Cytokine receptor like factor 1

0.50	GO:0046513	ceramide biosynthetic process
0.42	GO:0072721	cellular response to dithiothreitol
0.41	GO:0036146	cellular response to mycotoxin
0.41	GO:0071492	cellular response to UV-A
0.40	GO:0051974	negative regulation of telomerase activity
0.39	GO:0035690	cellular response to drug
0.37	GO:0007420	brain development
0.36	GO:0010469	regulation of receptor activity
0.36	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.36	GO:0060395	SMAD protein signal transduction

0.52	GO:0050291	sphingosine N-acyltransferase activity
0.36	GO:0048018	receptor ligand activity
0.36	GO:0005160	transforming growth factor beta receptor binding

0.45	GO:0005783	endoplasmic reticulum
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.35	GO:0005576	extracellular region
0.34	GO:0044431	Golgi apparatus part
0.34	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

0.52

EC:2.3.1.24

GO:0050291

sp|P27546|MAP4_MOUSE
Microtubule-associated protein 4
Search

MAP4

0.59	Microtubule-associated protein (Fragment)

0.53	GO:1902856	negative regulation of non-motile cilium assembly
0.51	GO:0051012	microtubule sliding
0.49	GO:0051294	establishment of spindle orientation
0.48	GO:0007052	mitotic spindle organization
0.43	GO:0031175	neuron projection development
0.43	GO:0051301	cell division

0.74

GO:0015631

tubulin binding

0.73	GO:0005874	microtubule
0.49	GO:0005737	cytoplasm
0.48	GO:0120025	plasma membrane bounded cell projection
0.48	GO:0097458	neuron part
0.47	GO:0072686	mitotic spindle
0.47	GO:0032279	asymmetric synapse
0.47	GO:0099572	postsynaptic specialization
0.44	GO:0044463	cell projection part
0.42	GO:0005875	microtubule associated complex
0.39	GO:0005886	plasma membrane

sp|P27548|CD40L_MOUSE
CD40 ligand
Search

sp|P27573|MYP0_MOUSE
Myelin protein P0
Search

MPZ

0.97	Myelin protein zero

0.59	GO:0098743	cell aggregation
0.58	GO:0042552	myelination
0.55	GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules
0.45	GO:0023052	signaling
0.45	GO:0007154	cell communication
0.43	GO:0051716	cellular response to stimulus
0.41	GO:0065007	biological regulation
0.39	GO:0045217	cell-cell junction maintenance
0.35	GO:0060028	convergent extension involved in axis elongation

0.35	GO:0000062	fatty-acyl-CoA binding
0.35	GO:0005515	protein binding
0.34	GO:0005198	structural molecule activity

0.77	GO:0043209	myelin sheath
0.67	GO:0005887	integral component of plasma membrane
0.39	GO:0016323	basolateral plasma membrane
0.39	GO:0005791	rough endoplasmic reticulum
0.38	GO:0005764	lysosome
0.33	GO:0005925	focal adhesion
0.33	GO:0009986	cell surface

sp|P27577|ETS1_MOUSE
Protein C-ets-1
Search

ETS1

0.71	ETS proto-oncogene 1, transcription factor

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0030578	PML body organization
0.55	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell
0.54	GO:0061614	pri-miRNA transcription by RNA polymerase II
0.54	GO:0045648	positive regulation of erythrocyte differentiation
0.53	GO:0010595	positive regulation of endothelial cell migration
0.52	GO:0043535	regulation of blood vessel endothelial cell migration
0.51	GO:0045765	regulation of angiogenesis

0.65	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.49	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0042802	identical protein binding
0.47	GO:0003690	double-stranded DNA binding
0.40	GO:0035035	histone acetyltransferase binding
0.34	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.45	GO:0070013	intracellular organelle lumen
0.41	GO:0044446	intracellular organelle part
0.33	GO:0042025	host cell nucleus
0.33	GO:0005737	cytoplasm

sp|P27600|GNA12_MOUSE
Guanine nucleotide-binding protein subunit alpha-12
Search

GNA12

0.95	Guanine nucleotide-binding protein subunit alpha-12

0.72	GO:0007264	small GTPase mediated signal transduction
0.68	GO:0007186	G-protein coupled receptor signaling pathway
0.49	GO:0048598	embryonic morphogenesis
0.49	GO:0043149	stress fiber assembly
0.48	GO:0060973	cell migration involved in heart development
0.48	GO:0014003	oligodendrocyte development
0.48	GO:0090504	epiboly
0.47	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin
0.47	GO:0009826	unidimensional cell growth
0.46	GO:0001667	ameboidal-type cell migration

0.78	GO:0031683	G-protein beta/gamma-subunit complex binding
0.76	GO:0001664	G-protein coupled receptor binding
0.65	GO:0003924	GTPase activity
0.63	GO:0019001	guanyl nucleotide binding
0.63	GO:0032550	purine ribonucleoside binding
0.62	GO:0004871	signal transducer activity
0.52	GO:0032555	purine ribonucleotide binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0045296	cadherin binding
0.35	GO:0046872	metal ion binding

0.44	GO:0031526	brush border membrane
0.44	GO:0005622	intracellular
0.42	GO:1905360	GTPase complex
0.41	GO:0019897	extrinsic component of plasma membrane
0.41	GO:0009898	cytoplasmic side of plasma membrane
0.40	GO:0016328	lateral plasma membrane
0.39	GO:0098797	plasma membrane protein complex
0.38	GO:0005925	focal adhesion

sp|P27601|GNA13_MOUSE
Guanine nucleotide-binding protein subunit alpha-13
Search

GNA13

0.93	Heterotrimeric guanine nucleotide binding protein subunit alpha-13

0.74	GO:0007264	small GTPase mediated signal transduction
0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.49	GO:0002009	morphogenesis of an epithelium
0.48	GO:0072359	circulatory system development
0.48	GO:0009790	embryo development
0.47	GO:0043149	stress fiber assembly
0.46	GO:0019933	cAMP-mediated signaling
0.46	GO:0031584	activation of phospholipase D activity
0.46	GO:0030154	cell differentiation
0.45	GO:0009826	unidimensional cell growth

0.80	GO:0031683	G-protein beta/gamma-subunit complex binding
0.78	GO:0001664	G-protein coupled receptor binding
0.66	GO:0003924	GTPase activity
0.64	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.63	GO:0004871	signal transducer activity
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0045296	cadherin binding
0.35	GO:0005089	Rho guanyl-nucleotide exchange factor activity

0.45	GO:0031526	brush border membrane
0.44	GO:0005622	intracellular
0.42	GO:1905360	GTPase complex
0.41	GO:0019897	extrinsic component of plasma membrane
0.41	GO:0009898	cytoplasmic side of plasma membrane
0.38	GO:0098797	plasma membrane protein complex
0.38	GO:0005925	focal adhesion
0.38	GO:0031982	vesicle
0.38	GO:0043230	extracellular organelle
0.37	GO:0005615	extracellular space

sp|P27612|PLAP_MOUSE
Phospholipase A-2-activating protein
Search

PLAA

0.91	phospholipase A-2-activating protein isoform X1

0.86	GO:0032430	positive regulation of phospholipase A2 activity
0.86	GO:1900045	negative regulation of protein K63-linked ubiquitination
0.86	GO:1903423	positive regulation of synaptic vesicle recycling
0.85	GO:2001224	positive regulation of neuron migration
0.85	GO:1903861	positive regulation of dendrite extension
0.83	GO:0006692	prostanoid metabolic process
0.81	GO:0071222	cellular response to lipopolysaccharide
0.81	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
0.79	GO:0016236	macroautophagy
0.76	GO:0006954	inflammatory response

0.86	GO:0016005	phospholipase A2 activator activity
0.63	GO:0043130	ubiquitin binding
0.38	GO:0016905	myosin heavy chain kinase activity

0.78	GO:0070062	extracellular exosome
0.73	GO:0045202	synapse
0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.46	GO:0030054	cell junction

0.38

EC:2.7.11.7

GO:0016905

sp|P27641|XRCC5_MOUSE
X-ray repair cross-complementing protein 5
Search

XRCC5

0.93	X-ray repair cross-complementing protein 5

0.78	GO:0006303	double-strand break repair via nonhomologous end joining
0.76	GO:0000723	telomere maintenance
0.68	GO:0032508	DNA duplex unwinding
0.63	GO:0006310	DNA recombination
0.60	GO:1904430	negative regulation of t-circle formation
0.59	GO:0010212	response to ionizing radiation
0.58	GO:0060218	hematopoietic stem cell differentiation
0.57	GO:0032212	positive regulation of telomere maintenance via telomerase
0.56	GO:0048660	regulation of smooth muscle cell proliferation
0.56	GO:1990823	response to leukemia inhibitory factor

0.80	GO:0042162	telomeric DNA binding
0.71	GO:0003684	damaged DNA binding
0.70	GO:0004003	ATP-dependent DNA helicase activity
0.59	GO:0051575	5'-deoxyribose-5-phosphate lyase activity
0.55	GO:0008022	protein C-terminus binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0044212	transcription regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.49	GO:0044877	macromolecular complex binding
0.47	GO:0030554	adenyl nucleotide binding

0.81	GO:0043564	Ku70:Ku80 complex
0.58	GO:0070419	nonhomologous end joining complex
0.56	GO:0000784	nuclear chromosome, telomeric region
0.50	GO:0032993	protein-DNA complex
0.48	GO:0005654	nucleoplasm
0.45	GO:0030529	intracellular ribonucleoprotein complex
0.42	GO:0005886	plasma membrane
0.39	GO:0005737	cytoplasm
0.36	GO:0005730	nucleolus
0.35	GO:0031983	vesicle lumen

sp|P27656|LIPC_MOUSE
Hepatic triacylglycerol lipase
Search

LIPC

0.97	Hepatic triacylglycerol lipase

0.61	GO:0006629	lipid metabolic process
0.55	GO:0034372	very-low-density lipoprotein particle remodeling
0.55	GO:0034374	low-density lipoprotein particle remodeling
0.55	GO:0034375	high-density lipoprotein particle remodeling
0.53	GO:0070328	triglyceride homeostasis
0.53	GO:0042632	cholesterol homeostasis
0.52	GO:0030301	cholesterol transport
0.50	GO:1902652	secondary alcohol metabolic process
0.46	GO:0072330	monocarboxylic acid biosynthetic process
0.44	GO:0044248	cellular catabolic process

0.78	GO:0004806	triglyceride lipase activity
0.41	GO:0008201	heparin binding
0.38	GO:0034185	apolipoprotein binding
0.38	GO:0030169	low-density lipoprotein particle binding
0.37	GO:0035478	chylomicron binding
0.36	GO:0004620	phospholipase activity
0.36	GO:0043395	heparan sulfate proteoglycan binding
0.36	GO:0047372	acylglycerol lipase activity
0.34	GO:0008289	lipid binding
0.33	GO:0016746	transferase activity, transferring acyl groups

0.65	GO:0005576	extracellular region
0.41	GO:1990777	lipoprotein particle
0.35	GO:0005902	microvillus
0.35	GO:0005770	late endosome
0.35	GO:0005769	early endosome
0.35	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0009986	cell surface

0.78

EC:3.1.1.3

GO:0004806

sp|P27659|RL3_MOUSE
60S ribosomal protein L3
Search

RPL3

0.61	Ribosomal protein L3

0.59	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.50	GO:0071353	cellular response to interleukin-4
0.46	GO:0031017	exocrine pancreas development
0.43	GO:0000027	ribosomal large subunit assembly
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.62	GO:0003735	structural constituent of ribosome
0.38	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.60	GO:0005840	ribosome
0.47	GO:0005730	nucleolus
0.46	GO:0005829	cytosol
0.41	GO:0043234	protein complex
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome

0.32

GO:0016787

sp|P27661|H2AX_MOUSE
Histone H2AX
Search

sp|P27664|PDE6A_MOUSE
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha
Search

PDE6A

0.54	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha

0.61	GO:0007165	signal transduction
0.60	GO:0007601	visual perception
0.59	GO:0051480	regulation of cytosolic calcium ion concentration
0.56	GO:0046037	GMP metabolic process
0.47	GO:0060041	retina development in camera-type eye
0.45	GO:0009583	detection of light stimulus
0.37	GO:0045494	photoreceptor cell maintenance
0.37	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.36	GO:0071482	cellular response to light stimulus
0.35	GO:0198738	cell-cell signaling by wnt

0.80	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.54	GO:0046872	metal ion binding

0.48	GO:0001750	photoreceptor outer segment
0.39	GO:0060170	ciliary membrane

0.80

EC:3.1.4.17

GO:0004114

sp|P27671|RGRF1_MOUSE
Ras-specific guanine nucleotide-releasing factor 1
Search

RASGRF1

0.97	RAS protein-specific guanine nucleotide-releasing factor 1

0.78	GO:0035023	regulation of Rho protein signal transduction
0.76	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.53	GO:0035020	regulation of Rac protein signal transduction
0.53	GO:0034976	response to endoplasmic reticulum stress
0.52	GO:1900449	regulation of glutamate receptor signaling pathway
0.52	GO:0048168	regulation of neuronal synaptic plasticity
0.50	GO:1904062	regulation of cation transmembrane transport
0.49	GO:0008283	cell proliferation
0.49	GO:0031175	neuron projection development

0.77	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.53	GO:0035254	glutamate receptor binding
0.35	GO:0030971	receptor tyrosine kinase binding
0.35	GO:0008022	protein C-terminus binding
0.35	GO:0008234	cysteine-type peptidase activity
0.34	GO:0005096	GTPase activator activity
0.34	GO:0005516	calmodulin binding
0.33	GO:0004797	thymidine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.51	GO:0030426	growth cone
0.45	GO:0005829	cytosol
0.37	GO:0005783	endoplasmic reticulum
0.36	GO:0097440	apical dendrite
0.35	GO:0016327	apicolateral plasma membrane
0.35	GO:0016323	basolateral plasma membrane
0.35	GO:0043025	neuronal cell body
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.35

GO:0008234

sp|P27681|GBRG3_MOUSE
Gamma-aminobutyric acid receptor subunit gamma-3
Search

0.94	Gamma-aminobutyric acid type A receptor epsilon subunit

0.81	GO:0007214	gamma-aminobutyric acid signaling pathway
0.72	GO:0006821	chloride transport
0.59	GO:0034220	ion transmembrane transport
0.37	GO:0042493	response to drug
0.36	GO:0007268	chemical synaptic transmission

0.80	GO:0004890	GABA-A receptor activity
0.72	GO:0005230	extracellular ligand-gated ion channel activity
0.40	GO:0005254	chloride channel activity
0.35	GO:0050811	GABA receptor binding

0.53	GO:0005886	plasma membrane
0.41	GO:0034707	chloride channel complex
0.40	GO:0098794	postsynapse
0.40	GO:0030054	cell junction
0.34	GO:0043235	receptor complex

sp|P27699|CREM_MOUSE
cAMP-responsive element modulator
Search

CREM

0.92	cAMP-responsive element modulator

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:1902679	negative regulation of RNA biosynthetic process
0.45	GO:0006687	glycosphingolipid metabolic process
0.44	GO:0007283	spermatogenesis
0.42	GO:1902680	positive regulation of RNA biosynthetic process
0.40	GO:0048384	retinoic acid receptor signaling pathway
0.39	GO:0042752	regulation of circadian rhythm
0.39	GO:0048511	rhythmic process

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.50	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0008140	cAMP response element binding protein binding

0.61	GO:0005634	nucleus
0.43	GO:0005667	transcription factor complex
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P27773|PDIA3_MOUSE
Protein disulfide-isomerase A3
Search

PDIA3

0.61	Protein disulfide-isomerase A3

0.68	GO:0045454	cell redox homeostasis
0.68	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway
0.64	GO:0034976	response to endoplasmic reticulum stress
0.53	GO:0006457	protein folding
0.53	GO:1904148	cellular response to nonylphenol
0.52	GO:1901423	response to benzene
0.51	GO:1903334	positive regulation of protein folding
0.51	GO:0033595	response to genistein
0.49	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.49	GO:0071305	cellular response to vitamin D

0.72	GO:0003756	protein disulfide isomerase activity
0.64	GO:0015037	peptide disulfide oxidoreductase activity
0.59	GO:0042802	identical protein binding
0.50	GO:0019153	protein-disulfide reductase (glutathione) activity
0.49	GO:0042288	MHC class I protein binding
0.46	GO:0004629	phospholipase C activity
0.44	GO:0004197	cysteine-type endopeptidase activity
0.43	GO:0003723	RNA binding

0.75	GO:0042470	melanosome
0.73	GO:0005788	endoplasmic reticulum lumen
0.65	GO:0043209	myelin sheath
0.63	GO:0009986	cell surface
0.59	GO:0005615	extracellular space
0.53	GO:0005925	focal adhesion
0.52	GO:1903561	extracellular vesicle
0.49	GO:0042825	TAP complex
0.48	GO:0005790	smooth endoplasmic reticulum
0.47	GO:0055038	recycling endosome membrane

0.72

EC:5.3.4.1

GO:0003756

sp|P27782|LEF1_MOUSE
Lymphoid enhancer-binding factor 1
Search

LEF1

0.94	Lymphoid enhancer-binding factor 1

0.76	GO:0016055	Wnt signaling pathway
0.69	GO:0006357	regulation of transcription by RNA polymerase II
0.65	GO:0061152	trachea submucosa development
0.64	GO:0021943	formation of radial glial scaffolds
0.64	GO:0021861	forebrain radial glial cell differentiation
0.64	GO:0071865	regulation of apoptotic process in bone marrow
0.63	GO:0032696	negative regulation of interleukin-13 production
0.63	GO:0032714	negative regulation of interleukin-5 production
0.63	GO:0021873	forebrain neuroblast division
0.63	GO:0048341	paraxial mesoderm formation

0.82	GO:0008013	beta-catenin binding
0.63	GO:0070016	armadillo repeat domain binding
0.63	GO:0045295	gamma-catenin binding
0.61	GO:0070742	C2H2 zinc finger domain binding
0.61	GO:0030331	estrogen receptor binding
0.60	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.60	GO:0030284	estrogen receptor activity
0.60	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.60	GO:0008301	DNA binding, bending
0.59	GO:0035326	enhancer binding

0.60	GO:1990907	beta-catenin-TCF complex
0.51	GO:0032993	protein-DNA complex
0.40	GO:0005737	cytoplasm
0.36	GO:0005654	nucleoplasm

sp|P27784|CCL6_MOUSE
C-C motif chemokine 6
Search

0.55	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.66	GO:0071674	mononuclear cell migration
0.65	GO:0072676	lymphocyte migration
0.64	GO:1990266	neutrophil migration
0.63	GO:0071347	cellular response to interleukin-1
0.63	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.62	GO:0071356	cellular response to tumor necrosis factor
0.62	GO:0070098	chemokine-mediated signaling pathway

0.84	GO:0008009	chemokine activity
0.66	GO:0048020	CCR chemokine receptor binding
0.53	GO:0004698	calcium-dependent protein kinase C activity
0.52	GO:0042056	chemoattractant activity
0.52	GO:0016004	phospholipase activator activity
0.42	GO:0042802	identical protein binding
0.38	GO:0008201	heparin binding
0.35	GO:0003735	structural constituent of ribosome

0.73	GO:0005615	extracellular space
0.43	GO:0005829	cytosol
0.36	GO:0015934	large ribosomal subunit

0.53

GO:0004698

sp|P27786|CP17A_MOUSE
Steroid 17-alpha-hydroxylase/17,20 lyase
Search

CYP17A1

0.93	steroid 17-alpha-hydroxylase/17,20 lyase precursor

0.71	GO:0006694	steroid biosynthetic process
0.67	GO:0042448	progesterone metabolic process
0.65	GO:0007548	sex differentiation
0.60	GO:0042446	hormone biosynthetic process
0.58	GO:0008211	glucocorticoid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.41	GO:0042181	ketone biosynthetic process
0.38	GO:0008209	androgen metabolic process
0.37	GO:0018879	biphenyl metabolic process
0.37	GO:0018963	phthalate metabolic process

0.84	GO:0004508	steroid 17-alpha-monooxygenase activity
0.83	GO:0047442	17-alpha-hydroxyprogesterone aldolase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.46	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
0.35	GO:0019825	oxygen binding
0.32	GO:0070330	aromatase activity

0.53	GO:0043025	neuronal cell body
0.53	GO:0030424	axon
0.44	GO:0005739	mitochondrion
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:1.14.99.9

GO:0004508

sp|P27790|CENPB_MOUSE
Major centromere autoantigen B
Search

CENPB

0.94	Major centromere autoantigen B

0.36	GO:0048666	neuron development
0.36	GO:0120036	plasma membrane bounded cell projection organization
0.36	GO:0042273	ribosomal large subunit biogenesis
0.34	GO:0050794	regulation of cellular process
0.34	GO:0051716	cellular response to stimulus
0.34	GO:0006996	organelle organization
0.34	GO:0023052	signaling
0.34	GO:0007154	cell communication
0.34	GO:0065004	protein-DNA complex assembly
0.34	GO:0051641	cellular localization

0.80	GO:0003696	satellite DNA binding
0.68	GO:0003682	chromatin binding
0.39	GO:0019237	centromeric DNA binding
0.34	GO:0005198	structural molecule activity
0.34	GO:0046872	metal ion binding
0.34	GO:0004871	signal transducer activity
0.33	GO:0003723	RNA binding
0.33	GO:0004872	receptor activity
0.33	GO:0005515	protein binding
0.33	GO:0140110	transcription regulator activity

0.69	GO:0000775	chromosome, centromeric region
0.61	GO:0005720	nuclear heterochromatin
0.58	GO:0000794	condensed nuclear chromosome
0.57	GO:0016604	nuclear body
0.37	GO:0005883	neurofilament
0.36	GO:0017053	transcriptional repressor complex
0.36	GO:0005730	nucleolus
0.34	GO:0012505	endomembrane system
0.33	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0043005	neuron projection

0.33	EC:2.3.1.48	GO:0004402
0.32	KEGG:R00093	GO:0016040

sp|P27792|LYL1_MOUSE
Protein lyl-1
Search

LYL1

0.90	Lymphoblastic leukemia-associated hematopoiesis regulator 1

0.63	GO:0060216	definitive hemopoiesis
0.60	GO:0071695	anatomical structure maturation
0.59	GO:0001568	blood vessel development
0.59	GO:0002521	leukocyte differentiation
0.55	GO:0042113	B cell activation
0.55	GO:0045893	positive regulation of transcription, DNA-templated
0.51	GO:0060217	hemangioblast cell differentiation
0.51	GO:0060375	regulation of mast cell differentiation
0.50	GO:0060018	astrocyte fate commitment
0.50	GO:0006357	regulation of transcription by RNA polymerase II

0.68	GO:0046983	protein dimerization activity
0.53	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.51	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.48	GO:0001158	enhancer sequence-specific DNA binding
0.47	GO:0042826	histone deacetylase binding
0.47	GO:0001085	RNA polymerase II transcription factor binding
0.46	GO:0000987	proximal promoter sequence-specific DNA binding
0.45	GO:0003682	chromatin binding
0.38	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity
0.36	GO:0000049	tRNA binding

0.50	GO:0033193	Lsd1/2 complex
0.46	GO:0000118	histone deacetylase complex
0.44	GO:0005667	transcription factor complex
0.44	GO:0000790	nuclear chromatin
0.30	GO:0016020	membrane

0.38

GO:0004809

sp|P27808|MGAT1_MOUSE
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
Search

MGAT1

0.90	N-acetylglucosaminyltransferase I mutant

0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.60	GO:0036211	protein modification process
0.57	GO:0006049	UDP-N-acetylglucosamine catabolic process
0.56	GO:0044267	cellular protein metabolic process
0.51	GO:0001701	in utero embryonic development
0.44	GO:0035283	central nervous system segmentation
0.44	GO:0035010	encapsulation of foreign target
0.43	GO:0016319	mushroom body development
0.42	GO:0008340	determination of adult lifespan

0.77	GO:0008375	acetylglucosaminyltransferase activity
0.49	GO:0140103	catalytic activity, acting on a glycoprotein
0.35	GO:0046872	metal ion binding
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005797	Golgi medial cisterna
0.38	GO:0000139	Golgi membrane
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.77

GO:0008375

sp|P27811|KLRBA_MOUSE
Killer cell lectin-like receptor subfamily B member 1A
Search

0.97	Killer cell lectin like receptor B1

0.45	GO:0042269	regulation of natural killer cell mediated cytotoxicity
0.44	GO:0002716	negative regulation of natural killer cell mediated immunity
0.44	GO:0001911	negative regulation of leukocyte mediated cytotoxicity
0.38	GO:0002717	positive regulation of natural killer cell mediated immunity
0.38	GO:0001912	positive regulation of leukocyte mediated cytotoxicity
0.38	GO:0030101	natural killer cell activation
0.34	GO:0007166	cell surface receptor signaling pathway

0.69	GO:0030246	carbohydrate binding
0.42	GO:0042803	protein homodimerization activity
0.40	GO:0004872	receptor activity
0.34	GO:0004871	signal transducer activity

0.44	GO:0009897	external side of plasma membrane
0.40	GO:0005887	integral component of plasma membrane

sp|P27812|KRBBA_MOUSE
Killer cell lectin-like receptor subfamily B member 1B allele A
Search

0.97	Killer cell lectin like receptor B1

0.46	GO:0042269	regulation of natural killer cell mediated cytotoxicity
0.45	GO:0002716	negative regulation of natural killer cell mediated immunity
0.45	GO:0001911	negative regulation of leukocyte mediated cytotoxicity
0.38	GO:0002717	positive regulation of natural killer cell mediated immunity
0.38	GO:0001912	positive regulation of leukocyte mediated cytotoxicity
0.38	GO:0030101	natural killer cell activation
0.34	GO:0007166	cell surface receptor signaling pathway

0.69	GO:0030246	carbohydrate binding
0.42	GO:0042803	protein homodimerization activity
0.41	GO:0004872	receptor activity
0.34	GO:0004871	signal transducer activity

0.44	GO:0009897	external side of plasma membrane
0.40	GO:0005887	integral component of plasma membrane

sp|P27814|KLRBC_MOUSE
Killer cell lectin-like receptor subfamily B member 1C
Search

0.97	Killer cell lectin like receptor B1

0.46	GO:0042269	regulation of natural killer cell mediated cytotoxicity
0.44	GO:0002716	negative regulation of natural killer cell mediated immunity
0.44	GO:0001911	negative regulation of leukocyte mediated cytotoxicity
0.39	GO:0002717	positive regulation of natural killer cell mediated immunity
0.38	GO:0001912	positive regulation of leukocyte mediated cytotoxicity
0.38	GO:0030101	natural killer cell activation
0.34	GO:0007166	cell surface receptor signaling pathway

0.69	GO:0030246	carbohydrate binding
0.42	GO:0042803	protein homodimerization activity
0.40	GO:0004872	receptor activity
0.33	GO:0004871	signal transducer activity

0.44	GO:0009897	external side of plasma membrane
0.40	GO:0005887	integral component of plasma membrane

sp|P27870|VAV_MOUSE
Proto-oncogene vav
Search

VAV1

0.97	Vav 1 guanine nucleotide exchange factor

0.77	GO:0035023	regulation of Rho protein signal transduction
0.72	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.59	GO:0030593	neutrophil chemotaxis
0.58	GO:0008361	regulation of cell size
0.56	GO:0050778	positive regulation of immune response
0.56	GO:0007229	integrin-mediated signaling pathway
0.55	GO:0042269	regulation of natural killer cell mediated cytotoxicity
0.55	GO:0001912	positive regulation of leukocyte mediated cytotoxicity
0.54	GO:0045785	positive regulation of cell adhesion

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.59	GO:0048365	Rac GTPase binding
0.55	GO:0001784	phosphotyrosine residue binding
0.52	GO:0046872	metal ion binding
0.47	GO:0005154	epidermal growth factor receptor binding
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.34	GO:0005070	SH3/SH2 adaptor activity
0.34	GO:0005096	GTPase activator activity
0.33	GO:0003700	DNA binding transcription factor activity

0.50	GO:0005911	cell-cell junction
0.45	GO:0005622	intracellular
0.38	GO:0005886	plasma membrane
0.35	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|P27889|HNF1B_MOUSE
Hepatocyte nuclear factor 1-beta
Search

HNF1B

0.95	Hepatocyte nuclear factor 1-beta-A

0.73	GO:0045893	positive regulation of transcription, DNA-templated
0.59	GO:0035565	regulation of pronephros size
0.59	GO:0061296	negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
0.58	GO:0072181	mesonephric duct formation
0.58	GO:1900211	regulation of mesenchymal cell apoptotic process involved in metanephros development
0.58	GO:0039020	pronephric nephron tubule development
0.58	GO:0061017	hepatoblast differentiation
0.57	GO:0072095	regulation of branch elongation involved in ureteric bud branching
0.57	GO:0060677	ureteric bud elongation
0.57	GO:0072217	negative regulation of metanephros development

0.55	GO:0003677	DNA binding
0.54	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.53	GO:0001067	regulatory region nucleic acid binding
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0046982	protein heterodimerization activity
0.38	GO:0032403	protein complex binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.48	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P27931|IL1R2_MOUSE
Interleukin-1 receptor type 2
Search

IL1R2

0.97	Interleukin-1 receptor type II

0.79	GO:0019221	cytokine-mediated signaling pathway
0.72	GO:0032690	negative regulation of interleukin-1 alpha production
0.71	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway
0.70	GO:0050705	regulation of interleukin-1 alpha secretion
0.69	GO:0050711	negative regulation of interleukin-1 secretion
0.69	GO:1900016	negative regulation of cytokine production involved in inflammatory response
0.66	GO:0010955	negative regulation of protein processing
0.38	GO:0071347	cellular response to interleukin-1
0.37	GO:0006955	immune response

0.87	GO:0004910	interleukin-1, Type II, blocking receptor activity
0.69	GO:0019966	interleukin-1 binding

0.42	GO:0005737	cytoplasm
0.42	GO:0005576	extracellular region
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P28028|BRAF_MOUSE
Serine/threonine-protein kinase B-raf
Search

BRAF

0.88	Serine/threonine-protein kinase B-raf

0.63	GO:0006468	protein phosphorylation
0.61	GO:0035556	intracellular signal transduction
0.56	GO:2000301	negative regulation of synaptic vesicle exocytosis
0.56	GO:0002318	myeloid progenitor cell differentiation
0.56	GO:0010764	negative regulation of fibroblast migration
0.55	GO:0048680	positive regulation of axon regeneration
0.55	GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment
0.54	GO:0030878	thyroid gland development
0.54	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.54	GO:2000352	negative regulation of endothelial cell apoptotic process

0.76	GO:0005057	signal transducer activity, downstream of receptor
0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.50	GO:0031434	mitogen-activated protein kinase kinase binding
0.48	GO:0042802	identical protein binding
0.38	GO:0031267	small GTPase binding

0.51	GO:0044297	cell body
0.50	GO:0043005	neuron projection
0.46	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.42	GO:0005886	plasma membrane
0.37	GO:0005634	nucleus
0.33	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.69

GO:0004674

sp|P28033|CEBPB_MOUSE
CCAAT/enhancer-binding protein beta
Search

CEBPB

0.92	CCAAT enhancer binding protein beta

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0001889	liver development
0.56	GO:0045600	positive regulation of fat cell differentiation
0.55	GO:0045669	positive regulation of osteoblast differentiation
0.55	GO:0045444	fat cell differentiation
0.53	GO:0001892	embryonic placenta development
0.53	GO:0009617	response to bacterium
0.52	GO:0008285	negative regulation of cell proliferation

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0035035	histone acetyltransferase binding
0.51	GO:0019900	kinase binding
0.51	GO:0042803	protein homodimerization activity
0.50	GO:0042826	histone deacetylase binding
0.50	GO:0001047	core promoter binding
0.48	GO:0044389	ubiquitin-like protein ligase binding
0.47	GO:0003682	chromatin binding

0.50	GO:0016363	nuclear matrix
0.50	GO:0005654	nucleoplasm
0.48	GO:0000779	condensed chromosome, centromeric region
0.47	GO:0000790	nuclear chromatin
0.46	GO:0090575	RNA polymerase II transcription factor complex
0.37	GO:0005737	cytoplasm
0.35	GO:0005730	nucleolus
0.32	GO:0005886	plasma membrane

sp|P28047|WNT7B_MOUSE
Protein Wnt-7b
Search

sp|P28063|PSB8_MOUSE
Proteasome subunit beta type-8
Search

PSMB8

0.53	Proteasome subunit beta type

0.71	GO:0051603	proteolysis involved in cellular protein catabolic process
0.53	GO:0045444	fat cell differentiation
0.49	GO:0019882	antigen processing and presentation
0.49	GO:0052548	regulation of endopeptidase activity
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0060337	type I interferon signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation

0.77	GO:0070003	threonine-type peptidase activity
0.64	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding

0.75	GO:0005839	proteasome core complex
0.61	GO:0005634	nucleus
0.55	GO:1990111	spermatoproteasome complex
0.48	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part

sp|P28076|PSB9_MOUSE
Proteasome subunit beta type-9
Search

PSMB9

0.53	Proteasome subunit beta type

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.67	GO:0002376	immune system process
0.55	GO:2000116	regulation of cysteine-type endopeptidase activity
0.46	GO:0043632	modification-dependent macromolecule catabolic process
0.37	GO:0071347	cellular response to interleukin-1
0.36	GO:1901423	response to benzene
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0071257	cellular response to electrical stimulus
0.36	GO:0014889	muscle atrophy
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

0.77	GO:0004298	threonine-type endopeptidase activity
0.35	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding

0.76	GO:0005839	proteasome core complex
0.59	GO:0005634	nucleus
0.49	GO:0005829	cytosol
0.45	GO:1990111	spermatoproteasome complex
0.36	GO:0070062	extracellular exosome
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0044446	intracellular organelle part

0.77

EC:3.4.25

GO:0004298

sp|P28078|DMA_MOUSE
Class II histocompatibility antigen, M alpha chain
Search

HLA-DMA

0.64	Histocompatibility antigen DM heterodimer heavy chain

0.79	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
0.73	GO:0006955	immune response
0.57	GO:0002399	MHC class II protein complex assembly
0.56	GO:0002501	peptide antigen assembly with MHC protein complex
0.38	GO:0002478	antigen processing and presentation of exogenous peptide antigen
0.37	GO:0002636	positive regulation of germinal center formation
0.37	GO:0045059	positive thymic T cell selection
0.36	GO:0002922	positive regulation of humoral immune response
0.36	GO:0045582	positive regulation of T cell differentiation
0.36	GO:0002449	lymphocyte mediated immunity

0.56	GO:0023026	MHC class II protein complex binding
0.36	GO:0032395	MHC class II receptor activity

0.75	GO:0042613	MHC class II protein complex
0.49	GO:0009986	cell surface
0.42	GO:0043227	membrane-bounded organelle
0.40	GO:0043229	intracellular organelle
0.37	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space
0.36	GO:0098805	whole membrane
0.36	GO:0005581	collagen trimer
0.35	GO:0012505	endomembrane system
0.34	GO:0044422	organelle part

sp|P28184|MT3_MOUSE
Metallothionein-3
Search

0.75	Metallothionein-II, hippocampal

0.59	GO:0071248	cellular response to metal ion
0.57	GO:0097214	positive regulation of lysosomal membrane permeability
0.57	GO:0045926	negative regulation of growth
0.57	GO:2000376	positive regulation of oxygen metabolic process
0.57	GO:0055073	cadmium ion homeostasis
0.55	GO:0010940	positive regulation of necrotic cell death
0.55	GO:0060547	negative regulation of necrotic cell death
0.55	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
0.55	GO:0071732	cellular response to nitric oxide
0.55	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress

0.56	GO:0046870	cadmium ion binding
0.54	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.52	GO:0030295	protein kinase activator activity
0.48	GO:0008270	zinc ion binding
0.48	GO:0005507	copper ion binding
0.40	GO:0008144	drug binding
0.35	GO:0005515	protein binding
0.34	GO:0016209	antioxidant activity

0.56	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0016234	inclusion body
0.51	GO:0008021	synaptic vesicle
0.43	GO:0005634	nucleus
0.42	GO:0097450	astrocyte end-foot
0.41	GO:0043197	dendritic spine
0.40	GO:0014069	postsynaptic density
0.40	GO:0005791	rough endoplasmic reticulum
0.40	GO:0030424	axon
0.39	GO:0005741	mitochondrial outer membrane

sp|P28229|CXG1_MOUSE
Gap junction gamma-1 protein
Search

GJC1

0.64	Gap junction gamma-1 protein (Fragment)

0.61	GO:0086053	AV node cell to bundle of His cell communication by electrical coupling
0.61	GO:0016264	gap junction assembly
0.57	GO:0001570	vasculogenesis
0.56	GO:0048738	cardiac muscle tissue development
0.54	GO:0007601	visual perception
0.53	GO:0007268	chemical synaptic transmission
0.52	GO:0048468	cell development
0.45	GO:0034220	ion transmembrane transport
0.37	GO:0086021	SA node cell to atrial cardiac muscle cell communication by electrical coupling
0.36	GO:0009636	response to toxic substance

0.61	GO:1903763	gap junction channel activity involved in cell communication by electrical coupling
0.50	GO:0005216	ion channel activity
0.33	GO:0005515	protein binding

0.83	GO:0005922	connexin complex
0.38	GO:0043209	myelin sheath
0.35	GO:0014704	intercalated disc
0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

sp|P28230|CXB1_MOUSE
Gap junction beta-1 protein
Search

GJB1

0.64	Gap junction beta-1 protein (Fragment)

0.60	GO:0007154	cell communication
0.45	GO:0016264	gap junction assembly
0.40	GO:1905867	epididymis development
0.39	GO:0015868	purine ribonucleotide transport
0.37	GO:0023052	signaling
0.37	GO:0055085	transmembrane transport
0.36	GO:0051259	protein oligomerization
0.34	GO:0007399	nervous system development
0.34	GO:0007605	sensory perception of sound

0.52	GO:0042802	identical protein binding
0.47	GO:0046983	protein dimerization activity
0.46	GO:0005243	gap junction channel activity

0.83	GO:0005922	connexin complex
0.39	GO:0005737	cytoplasm
0.38	GO:0016328	lateral plasma membrane
0.36	GO:0012505	endomembrane system
0.35	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

sp|P28231|CXB3_MOUSE
Gap junction beta-3 protein
Search

GJB3

0.64	Gap junction beta-3 protein (Fragment)

0.59	GO:0007154	cell communication
0.51	GO:0001890	placenta development
0.45	GO:0042048	olfactory behavior
0.42	GO:0007608	sensory perception of smell
0.39	GO:0001701	in utero embryonic development
0.39	GO:0071300	cellular response to retinoic acid
0.38	GO:0043588	skin development
0.38	GO:0007283	spermatogenesis
0.36	GO:1905867	epididymis development
0.35	GO:0048568	embryonic organ development

0.35	GO:0005243	gap junction channel activity
0.33	GO:0005515	protein binding

0.81	GO:0005922	connexin complex
0.42	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:0005737	cytoplasm
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

sp|P28235|CXA4_MOUSE
Gap junction alpha-4 protein
Search

GJA4

0.64	Gap junction protein alpha 4

0.60	GO:0007154	cell communication
0.57	GO:0032501	multicellular organismal process
0.49	GO:0048856	anatomical structure development
0.43	GO:0055085	transmembrane transport
0.39	GO:0008016	regulation of heart contraction
0.39	GO:0006816	calcium ion transport
0.36	GO:0006950	response to stress
0.36	GO:0023052	signaling
0.35	GO:0007043	cell-cell junction assembly
0.34	GO:0043473	pigmentation

0.62	GO:0005243	gap junction channel activity
0.33	GO:0005515	protein binding

0.84	GO:0005922	connexin complex
0.34	GO:0005887	integral component of plasma membrane

sp|P28236|CXA8_MOUSE
Gap junction alpha-8 protein
Search

GJA8

0.64	Gap junction alpha-8 protein (Fragment)

0.60	GO:0007154	cell communication
0.57	GO:0002088	lens development in camera-type eye
0.50	GO:0007601	visual perception
0.42	GO:0051260	protein homooligomerization
0.42	GO:0055085	transmembrane transport
0.41	GO:0048050	post-embryonic eye morphogenesis
0.41	GO:0003161	cardiac conduction system development
0.40	GO:0055008	cardiac muscle tissue morphogenesis
0.39	GO:0008016	regulation of heart contraction
0.38	GO:0023052	signaling

0.58	GO:0005243	gap junction channel activity
0.34	GO:0005515	protein binding

0.84	GO:0005922	connexin complex
0.35	GO:0005887	integral component of plasma membrane

sp|P28271|ACOC_MOUSE
Cytoplasmic aconitate hydratase
Search

ACO1

0.92	Cytoplasmic aconitate hydratase

0.86	GO:0010040	response to iron(II) ion
0.76	GO:0006879	cellular iron ion homeostasis
0.50	GO:0050892	intestinal absorption
0.46	GO:0009791	post-embryonic development
0.46	GO:0006101	citrate metabolic process
0.44	GO:0006417	regulation of translation
0.41	GO:0009060	aerobic respiration
0.37	GO:0001889	liver development
0.30	GO:0044238	primary metabolic process

0.79	GO:0003994	aconitate hydratase activity
0.67	GO:0051539	4 iron, 4 sulfur cluster binding
0.53	GO:0030350	iron-responsive element binding
0.48	GO:0051538	3 iron, 4 sulfur cluster binding
0.38	GO:0046872	metal ion binding
0.37	GO:0048027	mRNA 5'-UTR binding
0.34	GO:0005515	protein binding

0.49	GO:0005737	cytoplasm
0.43	GO:0012505	endomembrane system
0.39	GO:0070062	extracellular exosome
0.39	GO:0043231	intracellular membrane-bounded organelle

0.79

EC:4.2.1.3

GO:0003994

sp|P28293|CATG_MOUSE
Cathepsin G
Search

0.92	Endogenous granzyme B

0.67	GO:0001909	leukocyte mediated cytotoxicity
0.63	GO:0002443	leukocyte mediated immunity
0.63	GO:0008626	granzyme-mediated apoptotic signaling pathway
0.61	GO:0006508	proteolysis
0.57	GO:0006955	immune response
0.57	GO:0006952	defense response
0.52	GO:0051851	modification by host of symbiont morphology or physiology
0.51	GO:0044130	negative regulation of growth of symbiont in host
0.50	GO:0009620	response to fungus
0.49	GO:0051883	killing of cells in other organism involved in symbiotic interaction

0.69	GO:0004252	serine-type endopeptidase activity
0.49	GO:0008201	heparin binding
0.35	GO:0005515	protein binding

0.65	GO:0030141	secretory granule
0.48	GO:0010494	cytoplasmic stress granule
0.46	GO:0031012	extracellular matrix
0.46	GO:0005615	extracellular space
0.40	GO:0005886	plasma membrane
0.38	GO:0044194	cytolytic granule
0.35	GO:0005882	intermediate filament
0.35	GO:0005766	primary lysosome
0.35	GO:0060205	cytoplasmic vesicle lumen
0.35	GO:0005775	vacuolar lumen

0.69

GO:0004252

sp|P28301|LYOX_MOUSE
Protein-lysine 6-oxidase
Search

LOX

0.86	Lysyl oxidase a

0.57	GO:0048251	elastic fiber assembly
0.56	GO:0035904	aorta development
0.56	GO:0030199	collagen fibril organization
0.55	GO:0030324	lung development
0.54	GO:0048514	blood vessel morphogenesis
0.53	GO:0007507	heart development
0.53	GO:0055114	oxidation-reduction process
0.43	GO:0051216	cartilage development
0.43	GO:0007517	muscle organ development
0.41	GO:0022008	neurogenesis

0.77	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
0.72	GO:0005507	copper ion binding
0.44	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0005515	protein binding
0.34	GO:0035091	phosphatidylinositol binding

0.52	GO:0005581	collagen trimer
0.51	GO:0005578	proteinaceous extracellular matrix
0.51	GO:0005615	extracellular space
0.37	GO:0005634	nucleus

0.77

EC:1.4.3

GO:0016641

sp|P28309|DEFA2_MOUSE
Alpha-defensin 2
Search

0.97	Cryptdin i

0.72	GO:0006952	defense response
0.70	GO:0009617	response to bacterium
0.46	GO:0071216	cellular response to biotic stimulus
0.45	GO:0033993	response to lipid
0.44	GO:1901700	response to oxygen-containing compound
0.43	GO:0071310	cellular response to organic substance
0.43	GO:0019730	antimicrobial humoral response
0.42	GO:0042493	response to drug
0.38	GO:0051673	membrane disruption in other organism
0.36	GO:0031640	killing of cells of other organism

0.37	GO:0008289	lipid binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity
0.33	GO:0043168	anion binding
0.33	GO:0097367	carbohydrate derivative binding

0.73	GO:0005615	extracellular space
0.36	GO:0030141	secretory granule

sp|P28310|DEFA3_MOUSE
Alpha-defensin 3
Search

0.97	Myeloid alpha defensin 9

0.72	GO:0006952	defense response
0.68	GO:0009617	response to bacterium
0.45	GO:0071216	cellular response to biotic stimulus
0.44	GO:0033993	response to lipid
0.42	GO:1901700	response to oxygen-containing compound
0.42	GO:0071310	cellular response to organic substance
0.42	GO:0019730	antimicrobial humoral response
0.41	GO:0042493	response to drug
0.38	GO:0031640	killing of cells of other organism
0.37	GO:0051673	membrane disruption in other organism

0.36	GO:0008289	lipid binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0046982	protein heterodimerization activity
0.33	GO:0043168	anion binding
0.33	GO:0097367	carbohydrate derivative binding

0.73	GO:0005615	extracellular space
0.35	GO:0030141	secretory granule

sp|P28311|DEFA4_MOUSE
Alpha-defensin 4
Search

0.97	Cryptdin i

0.72	GO:0006952	defense response
0.67	GO:0009617	response to bacterium
0.44	GO:0071216	cellular response to biotic stimulus
0.43	GO:0033993	response to lipid
0.43	GO:0019730	antimicrobial humoral response
0.42	GO:1901700	response to oxygen-containing compound
0.42	GO:0071310	cellular response to organic substance
0.41	GO:0042493	response to drug
0.38	GO:0051673	membrane disruption in other organism
0.38	GO:0031640	killing of cells of other organism

0.38	GO:0008289	lipid binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity
0.34	GO:0043168	anion binding
0.33	GO:0097367	carbohydrate derivative binding

0.73	GO:0005615	extracellular space
0.36	GO:0030141	secretory granule

sp|P28312|DEFA5_MOUSE
Alpha-defensin 5
Search

0.97	Cryptdin i

0.72	GO:0006952	defense response
0.69	GO:0009617	response to bacterium
0.45	GO:0071216	cellular response to biotic stimulus
0.44	GO:0033993	response to lipid
0.43	GO:1901700	response to oxygen-containing compound
0.43	GO:0019730	antimicrobial humoral response
0.42	GO:0071310	cellular response to organic substance
0.41	GO:0042493	response to drug
0.38	GO:0051673	membrane disruption in other organism
0.37	GO:0031640	killing of cells of other organism

0.37	GO:0008289	lipid binding
0.37	GO:0042803	protein homodimerization activity
0.36	GO:0046982	protein heterodimerization activity
0.33	GO:0043168	anion binding
0.33	GO:0097367	carbohydrate derivative binding

0.73	GO:0005615	extracellular space
0.35	GO:0030141	secretory granule

sp|P28322|ETV4_MOUSE
ETS translocation variant 4
Search

ETV4

0.97	ETS translocation variant 4

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:1902680	positive regulation of RNA biosynthetic process
0.50	GO:0030154	cell differentiation
0.48	GO:0007422	peripheral nervous system development
0.46	GO:0006366	transcription by RNA polymerase II
0.42	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.41	GO:0120036	plasma membrane bounded cell projection organization
0.41	GO:0033600	negative regulation of mammary gland epithelial cell proliferation

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.49	GO:0031974	membrane-enclosed lumen
0.45	GO:0043232	intracellular non-membrane-bounded organelle
0.44	GO:0044446	intracellular organelle part

sp|P28334|5HT1B_MOUSE
5-hydroxytryptamine receptor 1B
Search

HTR1B

0.97	5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

0.82	GO:0046849	bone remodeling
0.81	GO:0042310	vasoconstriction
0.80	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.79	GO:0050795	regulation of behavior
0.79	GO:0007631	feeding behavior
0.73	GO:0007268	chemical synaptic transmission
0.64	GO:0014063	negative regulation of serotonin secretion
0.62	GO:0071312	cellular response to alkaloid
0.59	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.59	GO:0071502	cellular response to temperature stimulus

0.81	GO:0099589	serotonin receptor activity
0.77	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.77	GO:0008227	G-protein coupled amine receptor activity
0.58	GO:0051378	serotonin binding
0.41	GO:0008144	drug binding
0.33	GO:0005515	protein binding

0.63	GO:0005887	integral component of plasma membrane
0.39	GO:0005737	cytoplasm

sp|P28352|APEX1_MOUSE
DNA-(apurinic or apyrimidinic site) lyase
Search

APEX1

0.65	DNA-(apurinic or apyrimidinic site) lyase

0.64	GO:0006281	DNA repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.57	GO:0043247	telomere maintenance in response to DNA damage
0.56	GO:0080111	DNA demethylation
0.55	GO:0043488	regulation of mRNA stability
0.51	GO:0042981	regulation of apoptotic process
0.48	GO:0045454	cell redox homeostasis
0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.42	GO:0014912	negative regulation of smooth muscle cell migration
0.42	GO:0071320	cellular response to cAMP

0.77	GO:0140080	class III/IV DNA-(apurinic or apyrimidinic site) lyase activity
0.77	GO:0140078	class I DNA-(apurinic or apyrimidinic site) lyase activity
0.65	GO:0004519	endonuclease activity
0.58	GO:0008309	double-stranded DNA exodeoxyribonuclease activity
0.56	GO:0003691	double-stranded telomeric DNA binding
0.55	GO:0031490	chromatin DNA binding
0.53	GO:0046872	metal ion binding
0.53	GO:0003713	transcription coactivator activity
0.51	GO:0008408	3'-5' exonuclease activity
0.50	GO:0003684	damaged DNA binding

0.58	GO:0005634	nucleus
0.58	GO:0005739	mitochondrion
0.53	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005813	centrosome
0.48	GO:0031974	membrane-enclosed lumen
0.41	GO:0005783	endoplasmic reticulum
0.39	GO:0005667	transcription factor complex
0.35	GO:0000781	chromosome, telomeric region
0.33	GO:0005840	ribosome

0.49

EC:3.1.4

GO:0008081

sp|P28357|HXD9_MOUSE
Homeobox protein Hox-D9
Search

HOXD9

0.73	Homeobox protein Hox-D9

0.64	GO:0007275	multicellular organism development
0.57	GO:0008344	adult locomotory behavior
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0007338	single fertilization
0.56	GO:0010468	regulation of gene expression
0.56	GO:0014706	striated muscle tissue development
0.55	GO:0006351	transcription, DNA-templated
0.55	GO:0061061	muscle structure development
0.54	GO:0051254	positive regulation of RNA metabolic process

0.64	GO:0043565	sequence-specific DNA binding
0.56	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.56	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0003690	double-stranded DNA binding
0.33	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.32	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.44	GO:0043232	intracellular non-membrane-bounded organelle
0.40	GO:0005667	transcription factor complex
0.37	GO:0016235	aggresome
0.37	GO:0005739	mitochondrion

sp|P28359|HXD10_MOUSE
Homeobox protein Hox-D10
Search

HOXD10

0.97	Homeobox protein Hox-D10 isoform A

0.58	GO:0021520	spinal cord motor neuron cell fate specification
0.57	GO:0048935	peripheral nervous system neuron development
0.57	GO:0035137	hindlimb morphogenesis
0.57	GO:0035136	forelimb morphogenesis
0.57	GO:0009954	proximal/distal pattern formation
0.56	GO:0050905	neuromuscular process
0.55	GO:0008344	adult locomotory behavior
0.55	GO:0030326	embryonic limb morphogenesis
0.55	GO:0048704	embryonic skeletal system morphogenesis
0.55	GO:0007519	skeletal muscle tissue development

0.61	GO:0043565	sequence-specific DNA binding
0.54	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.52	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003682	chromatin binding
0.50	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.59	GO:0005634	nucleus
0.53	GO:0036464	cytoplasmic ribonucleoprotein granule
0.48	GO:0005829	cytosol
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part

sp|P28474|ADHX_MOUSE
Alcohol dehydrogenase class-3
Search

ADH5

0.60	S-(hydroxymethyl)glutathione dehydrogenase

0.80	GO:0006069	ethanol oxidation
0.52	GO:0018119	peptidyl-cysteine S-nitrosylation
0.52	GO:0003016	respiratory system process
0.51	GO:0045777	positive regulation of blood pressure
0.50	GO:0051775	response to redox state
0.50	GO:0001523	retinoid metabolic process
0.50	GO:0051409	response to nitrosative stress
0.49	GO:0032496	response to lipopolysaccharide
0.48	GO:0046294	formaldehyde catabolic process
0.35	GO:0006068	ethanol catabolic process

0.81	GO:0051903	S-(hydroxymethyl)glutathione dehydrogenase activity
0.62	GO:0008270	zinc ion binding
0.53	GO:0018467	formaldehyde dehydrogenase activity
0.52	GO:0005504	fatty acid binding
0.50	GO:0004022	alcohol dehydrogenase (NAD) activity
0.46	GO:0042803	protein homodimerization activity
0.33	GO:0009055	electron transfer activity

0.41	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.81	EC:1.1.1.284	GO:0051903
0.81	KEGG:R06983 KEGG:R07140	GO:0051903

sp|P28481|CO2A1_MOUSE
Collagen alpha-1(II) chain
Search

COL2A1

0.88	Collagen type II alpha 1 chain

0.65	GO:0060272	embryonic skeletal joint morphogenesis
0.64	GO:0060174	limb bud formation
0.64	GO:0001502	cartilage condensation
0.63	GO:0071599	otic vesicle development
0.63	GO:0030199	collagen fibril organization
0.63	GO:0001958	endochondral ossification
0.63	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.63	GO:0060351	cartilage development involved in endochondral bone morphogenesis
0.63	GO:0030903	notochord development
0.62	GO:0002062	chondrocyte differentiation

0.80	GO:0005201	extracellular matrix structural constituent
0.66	GO:0048407	platelet-derived growth factor binding
0.65	GO:0042289	MHC class II protein binding
0.55	GO:0042802	identical protein binding
0.36	GO:0046872	metal ion binding

0.74	GO:0005581	collagen trimer
0.65	GO:0098643	banded collagen fibril
0.59	GO:0005604	basement membrane
0.55	GO:0005615	extracellular space
0.41	GO:0005737	cytoplasm
0.35	GO:0012505	endomembrane system
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0043231	intracellular membrane-bounded organelle

sp|P28563|DUS1_MOUSE
Dual specificity protein phosphatase 1
Search

DUSP1

0.71	Dual specificity protein phosphatase

0.85	GO:0000188	inactivation of MAPK activity
0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.50	GO:0035970	peptidyl-threonine dephosphorylation
0.50	GO:0001706	endoderm formation
0.48	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.44	GO:0042981	regulation of apoptotic process
0.41	GO:0071850	mitotic cell cycle arrest
0.40	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint
0.40	GO:0033574	response to testosterone
0.40	GO:0051447	negative regulation of meiotic cell cycle

0.85	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.75	GO:0004725	protein tyrosine phosphatase activity
0.51	GO:0008330	protein tyrosine/threonine phosphatase activity
0.48	GO:1990439	MAP kinase serine/threonine phosphatase activity
0.39	GO:0019838	growth factor binding
0.35	GO:0016301	kinase activity

0.46	GO:0005634	nucleus
0.40	GO:0043233	organelle lumen
0.38	GO:0005737	cytoplasm
0.38	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.85

EC:3.1.3

GO:0017017

sp|P28571|SC6A9_MOUSE
Sodium- and chloride-dependent glycine transporter 1
Search

SLC6A9

0.56	Solute carrier family 6 (neurotransmitter transporter, glycine), member 9

0.76	GO:0006836	neurotransmitter transport
0.69	GO:0003333	amino acid transmembrane transport
0.53	GO:0060092	regulation of synaptic transmission, glycinergic
0.53	GO:0015807	L-amino acid transport
0.52	GO:0007268	chemical synaptic transmission
0.52	GO:0015804	neutral amino acid transport
0.49	GO:0015893	drug transport
0.48	GO:0007626	locomotory behavior
0.47	GO:0060078	regulation of postsynaptic membrane potential
0.46	GO:0099643	signal release from synapse

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.73	GO:0005283	sodium:amino acid symporter activity
0.57	GO:0015187	glycine transmembrane transporter activity

0.63	GO:0005887	integral component of plasma membrane
0.51	GO:0044456	synapse part
0.44	GO:0097458	neuron part

sp|P28574|MAX_MOUSE
Protein max
Search

MAX

0.95	MYC associated factor X

0.52

GO:0000122

negative regulation of transcription by RNA polymerase II

0.68	GO:0046983	protein dimerization activity
0.57	GO:0070888	E-box binding
0.56	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding
0.55	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0042802	identical protein binding

0.82	GO:0071339	MLL1 complex
0.76	GO:0090575	RNA polymerase II transcription factor complex
0.51	GO:0000790	nuclear chromatin
0.50	GO:0032993	protein-DNA complex

sp|P28575|IPP_MOUSE
Actin-binding protein IPP
Search

IPP

0.94	Intracisternal A particle-promoted polypeptide

0.47	GO:0016567	protein ubiquitination
0.36	GO:0043551	regulation of phosphatidylinositol 3-kinase activity
0.34	GO:0006511	ubiquitin-dependent protein catabolic process
0.34	GO:0045893	positive regulation of transcription, DNA-templated
0.33	GO:0048741	skeletal muscle fiber development
0.33	GO:0035914	skeletal muscle cell differentiation
0.33	GO:0045214	sarcomere organization
0.33	GO:0097659	nucleic acid-templated transcription
0.32	GO:0010467	gene expression
0.32	GO:0034645	cellular macromolecule biosynthetic process

0.69	GO:0003779	actin binding
0.47	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0035014	phosphatidylinositol 3-kinase regulator activity
0.36	GO:0003676	nucleic acid binding
0.33	GO:0003700	DNA binding transcription factor activity
0.31	GO:0046872	metal ion binding

0.50	GO:0031463	Cul3-RING ubiquitin ligase complex
0.36	GO:0005942	phosphatidylinositol 3-kinase complex
0.36	GO:0015629	actin cytoskeleton
0.33	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.47

GO:0004842

sp|P28649|CP19A_MOUSE
Aromatase
Search

CYP19A1

0.81

Aromatase

0.62	GO:2000866	positive regulation of estradiol secretion
0.61	GO:0006710	androgen catabolic process
0.61	GO:0002677	negative regulation of chronic inflammatory response
0.61	GO:0010760	negative regulation of macrophage chemotaxis
0.60	GO:0061370	testosterone biosynthetic process
0.60	GO:0060736	prostate gland growth
0.59	GO:0030540	female genitalia development
0.59	GO:0060065	uterus development
0.58	GO:0008585	female gonad development
0.55	GO:0030879	mammary gland development

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.65	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.34	GO:0019825	oxygen binding
0.33	GO:0009055	electron transfer activity

0.50	GO:0005783	endoplasmic reticulum
0.38	GO:0044297	cell body
0.38	GO:0043195	terminal bouton
0.37	GO:0030425	dendrite
0.35	GO:0044309	neuron spine
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0008021	synaptic vesicle
0.35	GO:0031984	organelle subcompartment
0.35	GO:0098794	postsynapse
0.34	GO:0005829	cytosol

0.68

GO:0016705

sp|P28650|PURA1_MOUSE
Adenylosuccinate synthetase isozyme 1
Search

ADSSL1

0.45	Adenylosuccinate synthetase

0.72	GO:0044208	'de novo' AMP biosynthetic process
0.46	GO:0046040	IMP metabolic process
0.44	GO:0071257	cellular response to electrical stimulus
0.42	GO:0006531	aspartate metabolic process
0.40	GO:0014850	response to muscle activity
0.39	GO:0014074	response to purine-containing compound
0.39	GO:0060359	response to ammonium ion
0.38	GO:0035690	cellular response to drug
0.38	GO:0042594	response to starvation
0.37	GO:0006541	glutamine metabolic process

0.79	GO:0004019	adenylosuccinate synthase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.58	GO:0000287	magnesium ion binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0003779	actin binding
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0032403	protein complex binding
0.37	GO:0017048	Rho GTPase binding

0.47	GO:0005737	cytoplasm
0.37	GO:0005886	plasma membrane
0.35	GO:0070062	extracellular exosome

0.79	EC:6.3.4.4	GO:0004019
0.79	KEGG:R01135	GO:0004019

sp|P28651|CAH8_MOUSE
Carbonic anhydrase-related protein
Search

CA8

0.97	Carbonic anhydrase VIII

0.68	GO:0006730	one-carbon metabolic process
0.56	GO:0048015	phosphatidylinositol-mediated signaling
0.48	GO:0036269	swimming behavior
0.46	GO:0021549	cerebellum development
0.45	GO:0043009	chordate embryonic development

0.74	GO:0004089	carbonate dehydratase activity
0.60	GO:0008270	zinc ion binding
0.35	GO:0005515	protein binding

0.40	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.74

EC:4.2.1.1

GO:0004089

sp|P28652|KCC2B_MOUSE
Calcium/calmodulin-dependent protein kinase type II subunit beta
Search

CAMK2B

0.92	Calmodulin dependent protein kinase II beta subunit

0.63	GO:0006468	protein phosphorylation
0.46	GO:0018210	peptidyl-threonine modification
0.45	GO:0018209	peptidyl-serine modification
0.42	GO:0007399	nervous system development
0.42	GO:0090129	positive regulation of synapse maturation
0.42	GO:0060999	positive regulation of dendritic spine development
0.42	GO:0030154	cell differentiation
0.41	GO:0099175	regulation of postsynapse organization
0.41	GO:0010770	positive regulation of cell morphogenesis involved in differentiation
0.40	GO:0031346	positive regulation of cell projection organization

0.81	GO:0004683	calmodulin-dependent protein kinase activity
0.78	GO:0005516	calmodulin binding
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.48	GO:0042803	protein homodimerization activity
0.37	GO:0043274	phospholipase binding
0.35	GO:0019901	protein kinase binding
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.43	GO:0043005	neuron projection
0.41	GO:0033017	sarcoplasmic reticulum membrane
0.39	GO:0005815	microtubule organizing center
0.38	GO:0051233	spindle midzone
0.38	GO:0014069	postsynaptic density
0.37	GO:0005829	cytosol
0.36	GO:0043204	perikaryon
0.35	GO:0030666	endocytic vesicle membrane
0.35	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0005654	nucleoplasm

0.81

EC:2.7.11.17

GO:0004683

sp|P28653|PGS1_MOUSE
Biglycan
Search

BGN

0.96

Biglycan

0.60	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
0.49	GO:0046426	negative regulation of JAK-STAT cascade
0.47	GO:0006469	negative regulation of protein kinase activity
0.47	GO:0019221	cytokine-mediated signaling pathway
0.42	GO:0001974	blood vessel remodeling
0.37	GO:0030207	chondroitin sulfate catabolic process
0.37	GO:0030208	dermatan sulfate biosynthetic process
0.36	GO:0030206	chondroitin sulfate biosynthetic process
0.35	GO:0030198	extracellular matrix organization

0.57	GO:0050840	extracellular matrix binding
0.53	GO:0005539	glycosaminoglycan binding
0.48	GO:0004860	protein kinase inhibitor activity
0.35	GO:0005201	extracellular matrix structural constituent
0.31	GO:0005515	protein binding

0.75	GO:0005578	proteinaceous extracellular matrix
0.56	GO:0042383	sarcolemma
0.54	GO:0030133	transport vesicle
0.53	GO:0009986	cell surface
0.51	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:0043202	lysosomal lumen
0.36	GO:0005796	Golgi lumen

sp|P28654|PGS2_MOUSE
Decorin
Search

DCN

0.97

Decorin

0.60	GO:0050654	chondroitin sulfate proteoglycan metabolic process
0.60	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway
0.60	GO:0051901	positive regulation of mitochondrial depolarization
0.59	GO:0090141	positive regulation of mitochondrial fission
0.58	GO:0010596	negative regulation of endothelial cell migration
0.57	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.57	GO:0016239	positive regulation of macroautophagy
0.56	GO:0016525	negative regulation of angiogenesis
0.56	GO:0018149	peptide cross-linking
0.56	GO:1903510	mucopolysaccharide metabolic process

0.83	GO:0005518	collagen binding
0.56	GO:0050840	extracellular matrix binding
0.52	GO:0005539	glycosaminoglycan binding
0.48	GO:0004860	protein kinase inhibitor activity
0.41	GO:0047485	protein N-terminus binding
0.36	GO:0098633	collagen fibril binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0003723	RNA binding

0.76	GO:0005578	proteinaceous extracellular matrix
0.51	GO:0005615	extracellular space
0.43	GO:0098647	collagen beaded filament
0.40	GO:0005581	collagen trimer
0.36	GO:0005737	cytoplasm
0.33	GO:0012505	endomembrane system
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.32	GO:0043231	intracellular membrane-bounded organelle

sp|P28656|NP1L1_MOUSE
Nucleosome assembly protein 1-like 1
Search

NAP1L1

0.90	Nucleosome assembly protein 1 like 1

0.76	GO:0006334	nucleosome assembly
0.38	GO:0060215	primitive hemopoiesis
0.38	GO:0001878	response to yeast
0.37	GO:0007283	spermatogenesis
0.37	GO:0030154	cell differentiation
0.37	GO:0051260	protein homooligomerization
0.36	GO:0048522	positive regulation of cellular process
0.36	GO:0010557	positive regulation of macromolecule biosynthetic process
0.36	GO:0010628	positive regulation of gene expression
0.36	GO:0051173	positive regulation of nitrogen compound metabolic process

0.37	GO:0030332	cyclin binding
0.37	GO:0042393	histone binding
0.34	GO:0019900	kinase binding
0.34	GO:0003723	RNA binding

0.59	GO:0005634	nucleus
0.41	GO:0042470	melanosome
0.34	GO:0043005	neuron projection
0.30	GO:0016020	membrane

sp|P28658|ATX10_MOUSE
Ataxin-10
Search

ATXN10

0.94

HUMEEP

0.75	GO:0031175	neuron projection development
0.74	GO:0060271	cilium assembly
0.51	GO:0070207	protein homotrimerization

0.46	GO:0042802	identical protein binding
0.45	GO:0019899	enzyme binding
0.34	GO:0005509	calcium ion binding

0.78	GO:0048471	perinuclear region of cytoplasm
0.78	GO:0043025	neuronal cell body
0.77	GO:0030425	dendrite
0.66	GO:0005829	cytosol
0.54	GO:0005886	plasma membrane
0.42	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

sp|P28659|CELF1_MOUSE
CUGBP Elav-like family member 1
Search

CELF1

0.96	CUG triplet repeat RNA-binding protein 1

0.52	GO:0040018	positive regulation of multicellular organism growth
0.51	GO:0006376	mRNA splice site selection
0.51	GO:0007286	spermatid development
0.38	GO:1990402	embryonic liver development
0.38	GO:0043484	regulation of RNA splicing
0.38	GO:0061113	pancreas morphogenesis
0.38	GO:0061031	endodermal digestive tract morphogenesis
0.37	GO:0061014	positive regulation of mRNA catabolic process
0.37	GO:0001889	liver development
0.37	GO:0048588	developmental cell growth

0.59	GO:0003723	RNA binding
0.51	GO:0031369	translation initiation factor binding
0.35	GO:0000900	translation repressor activity, nucleic acid binding

0.46	GO:0005654	nucleoplasm
0.38	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P28660|NCKP1_MOUSE
Nck-associated protein 1
Search

NCKAP1

0.82	Nck-associated protein 1

0.73	GO:0016601	Rac protein signal transduction
0.73	GO:0010592	positive regulation of lamellipodium assembly
0.71	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation
0.57	GO:0045175	basal protein localization
0.56	GO:0048617	embryonic foregut morphogenesis
0.56	GO:0048340	paraxial mesoderm morphogenesis
0.55	GO:0007354	zygotic determination of anterior/posterior axis, embryo
0.55	GO:0048570	notochord morphogenesis
0.55	GO:0008078	mesodermal cell migration
0.55	GO:0045176	apical protein localization

0.71	GO:0048365	Rac GTPase binding
0.62	GO:0032403	protein complex binding

0.72	GO:0031209	SCAR complex
0.70	GO:0031258	lamellipodium membrane
0.59	GO:0031941	filamentous actin
0.57	GO:0001726	ruffle
0.52	GO:0005925	focal adhesion
0.52	GO:0070062	extracellular exosome
0.42	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|P28661|SEPT4_MOUSE
Septin-4
Search

SEPT4

0.94	Septin-4 isoform 1

0.54	GO:0030382	sperm mitochondrion organization
0.53	GO:0048240	sperm capacitation
0.53	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.51	GO:0031398	positive regulation of protein ubiquitination
0.49	GO:0051260	protein homooligomerization
0.49	GO:0007420	brain development
0.37	GO:0007179	transforming growth factor beta receptor signaling pathway
0.36	GO:0051301	cell division
0.36	GO:0007049	cell cycle
0.36	GO:0035335	peptidyl-tyrosine dephosphorylation

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0042803	protein homodimerization activity
0.45	GO:0003924	GTPase activity
0.44	GO:0000287	magnesium ion binding
0.37	GO:0004722	protein serine/threonine phosphatase activity
0.36	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0004672	protein kinase activity

0.55	GO:0097227	sperm annulus
0.53	GO:0031105	septin complex
0.50	GO:0043209	myelin sheath
0.44	GO:0005654	nucleoplasm
0.42	GO:0005739	mitochondrion

0.36

GO:0004725

sp|P28662|BRI3_MOUSE
Brain protein I3
Search

BRI3

0.97	Brain protein I3 isoform b

0.38

GO:0043312

neutrophil degranulation

0.52

GO:0042802

identical protein binding

0.44	GO:0005765	lysosomal membrane
0.38	GO:0042582	azurophil granule
0.37	GO:0030667	secretory granule membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P28663|SNAB_MOUSE
Beta-soluble NSF attachment protein
Search

NAPB

0.93	N-ethylmaleimide-sensitive factor attachment protein, beta a

0.69	GO:0006886	intracellular protein transport
0.64	GO:0035494	SNARE complex disassembly
0.63	GO:0010807	regulation of synaptic vesicle priming
0.61	GO:0035249	synaptic transmission, glutamatergic
0.50	GO:0045176	apical protein localization
0.47	GO:0007420	brain development
0.46	GO:0030182	neuron differentiation
0.45	GO:0061025	membrane fusion
0.39	GO:0045494	photoreceptor cell maintenance
0.38	GO:0043462	regulation of ATPase activity

0.61	GO:0019905	syntaxin binding
0.54	GO:0005483	soluble NSF attachment protein activity
0.37	GO:0032403	protein complex binding
0.35	GO:0008081	phosphoric diester hydrolase activity
0.34	GO:0004620	phospholipase activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0004871	signal transducer activity

0.63	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex
0.58	GO:0043209	myelin sheath
0.49	GO:0005774	vacuolar membrane
0.38	GO:0043195	terminal bouton
0.38	GO:0070062	extracellular exosome
0.34	GO:0005886	plasma membrane
0.34	GO:0000139	Golgi membrane
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.35

EC:3.1.4

GO:0008081

sp|P28665|MUG1_MOUSE
Murinoglobulin-1
Search

A2M

0.64	Alpha-macroglobulin

0.76	GO:0010951	negative regulation of endopeptidase activity
0.53	GO:0001869	negative regulation of complement activation, lectin pathway
0.45	GO:0007565	female pregnancy
0.42	GO:0032502	developmental process
0.38	GO:0006953	acute-phase response
0.36	GO:0009611	response to wounding
0.36	GO:0002438	acute inflammatory response to antigenic stimulus
0.36	GO:0002576	platelet degranulation
0.35	GO:0010037	response to carbon dioxide
0.35	GO:0022617	extracellular matrix disassembly

0.76	GO:0004866	endopeptidase inhibitor activity
0.53	GO:0043120	tumor necrosis factor binding
0.52	GO:0019959	interleukin-8 binding
0.51	GO:0019966	interleukin-1 binding
0.50	GO:0048306	calcium-dependent protein binding
0.49	GO:0002020	protease binding
0.45	GO:0005102	receptor binding
0.39	GO:0048403	brain-derived neurotrophic factor binding
0.39	GO:0048406	nerve growth factor binding
0.35	GO:0032403	protein complex binding

0.73	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.36	GO:0031093	platelet alpha granule lumen
0.34	GO:0005829	cytosol
0.32	GO:0019866	organelle inner membrane
0.32	GO:0031966	mitochondrial membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P28666|MUG2_MOUSE
Murinoglobulin-2
Search

A2M

0.64	Alpha-macroglobulin

0.76	GO:0010951	negative regulation of endopeptidase activity
0.52	GO:0001869	negative regulation of complement activation, lectin pathway
0.44	GO:0007565	female pregnancy
0.41	GO:0032502	developmental process
0.37	GO:0006953	acute-phase response
0.36	GO:0009611	response to wounding
0.35	GO:0002438	acute inflammatory response to antigenic stimulus
0.35	GO:0002576	platelet degranulation
0.35	GO:0022617	extracellular matrix disassembly
0.35	GO:0010037	response to carbon dioxide

0.76	GO:0004866	endopeptidase inhibitor activity
0.52	GO:0043120	tumor necrosis factor binding
0.52	GO:0019959	interleukin-8 binding
0.51	GO:0019966	interleukin-1 binding
0.49	GO:0048306	calcium-dependent protein binding
0.49	GO:0002020	protease binding
0.45	GO:0005102	receptor binding
0.39	GO:0048403	brain-derived neurotrophic factor binding
0.39	GO:0048406	nerve growth factor binding
0.35	GO:0032403	protein complex binding

0.73	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.36	GO:0031093	platelet alpha granule lumen
0.34	GO:0005829	cytosol
0.32	GO:0019866	organelle inner membrane
0.32	GO:0031966	mitochondrial membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P28667|MRP_MOUSE
MARCKS-related protein
Search

MARCKSL1

0.97	Myristoylated alanine rich protein kinase C substrate

0.53	GO:0008284	positive regulation of cell proliferation
0.41	GO:0051764	actin crosslink formation
0.40	GO:0051017	actin filament bundle assembly
0.39	GO:0051260	protein homooligomerization
0.38	GO:0010842	retina layer formation
0.38	GO:0035914	skeletal muscle cell differentiation
0.37	GO:0007420	brain development
0.37	GO:0060541	respiratory system development
0.36	GO:0003381	epithelial cell morphogenesis involved in gastrulation
0.36	GO:0016310	phosphorylation

0.79	GO:0005516	calmodulin binding
0.44	GO:0003779	actin binding
0.41	GO:0005080	protein kinase C binding
0.39	GO:0032403	protein complex binding
0.38	GO:0042802	identical protein binding
0.37	GO:0016301	kinase activity
0.33	GO:0001786	phosphatidylserine binding

0.43	GO:0071944	cell periphery
0.42	GO:0042585	germinal vesicle
0.40	GO:0032432	actin filament bundle
0.39	GO:0005813	centrosome
0.39	GO:0070062	extracellular exosome
0.39	GO:0099568	cytoplasmic region
0.34	GO:0005925	focal adhesion
0.34	GO:0044307	dendritic branch
0.33	GO:0032059	bleb
0.33	GO:0001520	outer dense fiber

sp|P28700|RXRA_MOUSE
Retinoic acid receptor RXR-alpha
Search

RXRA

0.91	Retinoic acid receptor RXR-alpha

0.77	GO:0043401	steroid hormone mediated signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
0.44	GO:0060687	regulation of branching involved in prostate gland morphogenesis
0.44	GO:0035357	peroxisome proliferator activated receptor signaling pathway
0.44	GO:0048384	retinoic acid receptor signaling pathway
0.44	GO:0060038	cardiac muscle cell proliferation

0.79	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.60	GO:0003700	DNA binding transcription factor activity
0.45	GO:0050692	DBD domain binding
0.45	GO:0050693	LBD domain binding
0.44	GO:0042809	vitamin D receptor binding
0.44	GO:0001972	retinoic acid binding
0.44	GO:0016922	ligand-dependent nuclear receptor binding
0.43	GO:0031490	chromatin DNA binding

0.60	GO:0005634	nucleus
0.41	GO:0043235	receptor complex
0.40	GO:0005667	transcription factor complex
0.40	GO:0000785	chromatin
0.39	GO:0070013	intracellular organelle lumen
0.35	GO:0030424	axon

sp|P28704|RXRB_MOUSE
Retinoic acid receptor RXR-beta
Search

RXRB

0.97	Retinoid X nuclear receptor beta

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0030522	intracellular receptor signaling pathway
0.51	GO:0051254	positive regulation of RNA metabolic process
0.50	GO:0010557	positive regulation of macromolecule biosynthetic process
0.50	GO:0031328	positive regulation of cellular biosynthetic process
0.39	GO:0060038	cardiac muscle cell proliferation

0.79	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.38	GO:0042809	vitamin D receptor binding
0.37	GO:0035326	enhancer binding
0.36	GO:0050692	DBD domain binding
0.36	GO:0050693	LBD domain binding

0.61	GO:0005634	nucleus
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:0043235	receptor complex
0.35	GO:0005581	collagen trimer
0.35	GO:0005667	transcription factor complex
0.34	GO:0000785	chromatin
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

sp|P28705|RXRG_MOUSE
Retinoic acid receptor RXR-gamma
Search

RXRG

0.89	Retinoid X receptor gamma

0.79	GO:0043401	steroid hormone mediated signaling pathway
0.63	GO:0048384	retinoic acid receptor signaling pathway
0.61	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
0.61	GO:0051289	protein homotetramerization
0.58	GO:0006351	transcription, DNA-templated

0.80	GO:0003707	steroid hormone receptor activity
0.67	GO:0004886	9-cis retinoic acid receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.58	GO:0001012	RNA polymerase II regulatory region DNA binding
0.54	GO:0003690	double-stranded DNA binding
0.36	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.61

GO:0005634

nucleus

sp|P28738|KIF5C_MOUSE
Kinesin heavy chain isoform 5C
Search

KIF5C

0.85	Kinesin heavy chain isoform 5C

0.74	GO:0007018	microtubule-based movement
0.62	GO:0030705	cytoskeleton-dependent intracellular transport
0.59	GO:0097120	receptor localization to synapse
0.54	GO:0007411	axon guidance
0.50	GO:0016192	vesicle-mediated transport
0.46	GO:1905152	positive regulation of voltage-gated sodium channel activity
0.44	GO:0008104	protein localization
0.44	GO:0035617	stress granule disassembly
0.44	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.43	GO:0031340	positive regulation of vesicle fusion

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.58	GO:0019894	kinesin binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0042623	ATPase activity, coupled
0.44	GO:0008432	JUN kinase binding
0.42	GO:0016307	phosphatidylinositol phosphate kinase activity

0.66	GO:0035253	ciliary rootlet
0.60	GO:0032839	dendrite cytoplasm
0.56	GO:0043025	neuronal cell body
0.54	GO:0005871	kinesin complex
0.49	GO:0005874	microtubule
0.48	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0044295	axonal growth cone
0.42	GO:0045335	phagocytic vesicle
0.41	GO:0005829	cytosol
0.40	GO:0005815	microtubule organizing center

0.42

GO:0016307

sp|P28740|KIF2A_MOUSE
Kinesin-like protein KIF2A
Search

sp|P28741|KIF3A_MOUSE
Kinesin-like protein KIF3A
Search

sp|P28776|I23O1_MOUSE
Indoleamine 2,3-dioxygenase 1
Search

IDO1

0.81	Indoleamine 2,3-dioxygenase

0.78	GO:0019441	tryptophan catabolic process to kynurenine
0.63	GO:0002534	cytokine production involved in inflammatory response
0.62	GO:0002678	positive regulation of chronic inflammatory response
0.62	GO:0002666	positive regulation of T cell tolerance induction
0.61	GO:0070234	positive regulation of T cell apoptotic process
0.61	GO:0034276	kynurenic acid biosynthetic process
0.61	GO:0036269	swimming behavior
0.61	GO:0002830	positive regulation of type 2 immune response
0.60	GO:0032693	negative regulation of interleukin-10 production
0.60	GO:0046007	negative regulation of activated T cell proliferation

0.65	GO:0033754	indoleamine 2,3-dioxygenase activity
0.63	GO:0020037	heme binding
0.57	GO:0004833	tryptophan 2,3-dioxygenase activity
0.54	GO:0046872	metal ion binding
0.36	GO:0019825	oxygen binding
0.36	GO:0016597	amino acid binding
0.35	GO:0004222	metalloendopeptidase activity
0.35	GO:0005515	protein binding
0.34	GO:0009055	electron transfer activity

0.61	GO:0030485	smooth muscle contractile fiber
0.58	GO:0032421	stereocilium bundle
0.38	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.65

EC:1.13.11.52

GO:0033754

sp|P28798|GRN_MOUSE
Granulins
Search

0.56

Granulins

0.69	GO:0048675	axon extension
0.52	GO:0071340	skeletal muscle acetylcholine-gated channel clustering
0.50	GO:0001889	liver development
0.38	GO:0006470	protein dephosphorylation
0.30	GO:0050679	positive regulation of epithelial cell proliferation
0.30	GO:0009790	embryo development
0.30	GO:0009966	regulation of signal transduction
0.30	GO:0022414	reproductive process
0.30	GO:0035188	hatching
0.30	GO:0065009	regulation of molecular function

0.40	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.30	GO:0005515	protein binding
0.30	GO:0030545	receptor regulator activity

0.62	GO:0005764	lysosome
0.60	GO:0005768	endosome
0.57	GO:0005783	endoplasmic reticulum
0.39	GO:0005886	plasma membrane
0.30	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane
0.30	GO:0005739	mitochondrion

0.40

EC:3.1.3

GO:0008138

sp|P28825|MEP1A_MOUSE
Meprin A subunit alpha
Search

MEP1A

0.91	Meprin A subunit alpha

0.61	GO:0006508	proteolysis
0.43	GO:1901998	toxin transport
0.43	GO:0045766	positive regulation of angiogenesis
0.37	GO:0007586	digestion

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.42	GO:0042802	identical protein binding
0.35	GO:0005509	calcium ion binding

0.47	GO:0017090	meprin A complex
0.40	GO:0070062	extracellular exosome
0.35	GO:0005887	integral component of plasma membrane

0.70

GO:0004222

sp|P28828|PTPRM_MOUSE
Receptor-type tyrosine-protein phosphatase mu
Search

PTPRM

0.43	Receptor-type tyrosine-protein phosphatase mu

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.57	GO:0010842	retina layer formation
0.57	GO:0031290	retinal ganglion cell axon guidance
0.57	GO:0001937	negative regulation of endothelial cell proliferation
0.57	GO:0010596	negative regulation of endothelial cell migration
0.55	GO:0016525	negative regulation of angiogenesis
0.53	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.49	GO:0042493	response to drug
0.45	GO:0007165	signal transduction
0.38	GO:0097755	positive regulation of blood vessel diameter

0.74	GO:0004725	protein tyrosine phosphatase activity
0.59	GO:0019198	transmembrane receptor protein phosphatase activity
0.54	GO:0045296	cadherin binding
0.48	GO:0042802	identical protein binding

0.55	GO:0005913	cell-cell adherens junction
0.55	GO:0030027	lamellipodium
0.53	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.74

GO:0004725

sp|P28843|DPP4_MOUSE
Dipeptidyl peptidase 4
Search

DPP4

0.84	Venom dipeptidylpeptidase IV

0.61

GO:0006508

proteolysis

0.69

GO:0004252

serine-type endopeptidase activity

0.30

GO:0031224

intrinsic component of membrane

0.69

GO:0004252

sp|P28862|MMP3_MOUSE
Stromelysin-1
Search

0.71	Matrix metalloproteinase

0.62	GO:0030574	collagen catabolic process
0.61	GO:0006508	proteolysis
0.58	GO:0010727	negative regulation of hydrogen peroxide metabolic process
0.55	GO:0032461	positive regulation of protein oligomerization
0.50	GO:0022617	extracellular matrix disassembly
0.49	GO:0030334	regulation of cell migration
0.47	GO:0003417	growth plate cartilage development
0.47	GO:0001958	endochondral ossification
0.47	GO:0030282	bone mineralization
0.40	GO:1903209	positive regulation of oxidative stress-induced cell death

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.48	GO:0005518	collagen binding
0.43	GO:0005509	calcium ion binding
0.38	GO:0004252	serine-type endopeptidase activity
0.37	GO:0001047	core promoter binding
0.35	GO:0043565	sequence-specific DNA binding
0.34	GO:0001968	fibronectin binding
0.34	GO:0050750	low-density lipoprotein particle receptor binding
0.33	GO:0048306	calcium-dependent protein binding

0.74	GO:0031012	extracellular matrix
0.47	GO:0042406	extrinsic component of endoplasmic reticulum membrane
0.41	GO:0005615	extracellular space
0.36	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.35	GO:0030425	dendrite
0.35	GO:0044297	cell body
0.35	GO:0005581	collagen trimer
0.35	GO:0005739	mitochondrion
0.34	GO:0046581	intercellular canaliculus

0.70

GO:0004222

sp|P28867|KPCD_MOUSE
Protein kinase C delta type
Search

PRKCD

0.97	Protein kinase C delta type

0.68	GO:0006915	apoptotic process
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.60	GO:2000753	positive regulation of glucosylceramide catabolic process
0.60	GO:2000755	positive regulation of sphingomyelin catabolic process
0.60	GO:1900163	positive regulation of phospholipid scramblase activity
0.59	GO:0023021	termination of signal transduction
0.59	GO:2000304	positive regulation of ceramide biosynthetic process
0.59	GO:0051490	negative regulation of filopodium assembly
0.58	GO:0032613	interleukin-10 production

0.82	GO:0004697	protein kinase C activity
0.57	GO:0043560	insulin receptor substrate binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0046872	metal ion binding
0.52	GO:0019901	protein kinase binding
0.50	GO:0008047	enzyme activator activity
0.38	GO:0004715	non-membrane spanning protein tyrosine kinase activity

0.67	GO:0048471	perinuclear region of cytoplasm
0.55	GO:0005634	nucleus
0.51	GO:0005911	cell-cell junction
0.48	GO:0005783	endoplasmic reticulum
0.48	GO:0005829	cytosol
0.47	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.42	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0042582	azurophil granule

0.82

EC:2.7.11.13

GO:0004697

sp|P29037|TBP_MOUSE
TATA-box-binding protein
Search

TBP

0.63	TATA-binding protein 1

0.69	GO:0006352	DNA-templated transcription, initiation
0.56	GO:0006359	regulation of transcription by RNA polymerase III
0.55	GO:0006366	transcription by RNA polymerase II
0.55	GO:0006383	transcription by RNA polymerase III
0.51	GO:0065004	protein-DNA complex assembly
0.44	GO:0007369	gastrulation
0.42	GO:0006402	mRNA catabolic process
0.37	GO:0007283	spermatogenesis
0.37	GO:0045893	positive regulation of transcription, DNA-templated
0.36	GO:0009792	embryo development ending in birth or egg hatching

0.60	GO:0001034	RNA polymerase III transcription factor activity, sequence-specific DNA binding
0.57	GO:0001093	TFIIB-class transcription factor binding
0.57	GO:0017162	aryl hydrocarbon receptor binding
0.55	GO:0001129	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly
0.55	GO:0003677	DNA binding
0.55	GO:0070491	repressing transcription factor binding
0.50	GO:0001067	regulatory region nucleic acid binding
0.48	GO:0019899	enzyme binding

0.56	GO:0097550	transcriptional preinitiation complex
0.56	GO:0001940	male pronucleus
0.56	GO:0001939	female pronucleus
0.54	GO:0005719	nuclear euchromatin
0.54	GO:0005669	transcription factor TFIID complex
0.53	GO:0005672	transcription factor TFIIA complex
0.38	GO:0005737	cytoplasm
0.35	GO:0000120	RNA polymerase I transcription factor complex

sp|P29121|PCSK4_MOUSE
Proprotein convertase subtilisin/kexin type 4
Search

FURIN

0.93	Furin, paired basic amino acid cleaving enzyme

0.61	GO:0006508	proteolysis
0.55	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process
0.55	GO:0032902	nerve growth factor production
0.54	GO:0051604	protein maturation
0.54	GO:0032911	negative regulation of transforming growth factor beta1 production
0.54	GO:0048240	sperm capacitation
0.54	GO:0007340	acrosome reaction
0.53	GO:0007339	binding of sperm to zona pellucida
0.53	GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process
0.49	GO:0008283	cell proliferation

0.69	GO:0004252	serine-type endopeptidase activity
0.54	GO:0048406	nerve growth factor binding
0.51	GO:0002020	protease binding
0.49	GO:0042277	peptide binding
0.49	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0046872	metal ion binding
0.34	GO:0008942	nitrite reductase [NAD(P)H] activity

0.54	GO:0002080	acrosomal membrane
0.50	GO:0030140	trans-Golgi network transport vesicle
0.49	GO:0098857	membrane microdomain
0.49	GO:0005802	trans-Golgi network
0.48	GO:0009986	cell surface
0.47	GO:0000139	Golgi membrane
0.46	GO:0005783	endoplasmic reticulum
0.37	GO:0010008	endosome membrane
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0005576	extracellular region

0.69	EC:3.4.21	GO:0004252
0.34	KEGG:R00787 KEGG:R00789	GO:0008942

sp|P29268|CTGF_MOUSE
Connective tissue growth factor
Search

CTGF

0.95	Connective tissue growth factor XCTGF

0.73	GO:0001558	regulation of cell growth
0.59	GO:0035988	chondrocyte proliferation
0.58	GO:0001502	cartilage condensation
0.57	GO:0051496	positive regulation of stress fiber assembly
0.57	GO:0032330	regulation of chondrocyte differentiation
0.56	GO:0046330	positive regulation of JNK cascade
0.55	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.55	GO:0030324	lung development
0.55	GO:0008543	fibroblast growth factor receptor signaling pathway
0.55	GO:0001894	tissue homeostasis

0.77	GO:0005520	insulin-like growth factor binding
0.58	GO:0005178	integrin binding
0.57	GO:0008201	heparin binding
0.55	GO:0008022	protein C-terminus binding
0.39	GO:0001968	fibronectin binding
0.37	GO:0008083	growth factor activity

0.63	GO:0005576	extracellular region
0.38	GO:0005801	cis-Golgi network
0.38	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005938	cell cortex
0.36	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane

sp|P29319|EPHA3_MOUSE
Ephrin type-A receptor 3
Search

EPHA3

0.91	Eph receptor A3, like

0.84	GO:0048013	ephrin receptor signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.68	GO:0071300	cellular response to retinoic acid
0.68	GO:0045806	negative regulation of endocytosis
0.67	GO:0051893	regulation of focal adhesion assembly
0.67	GO:1903078	positive regulation of protein localization to plasma membrane
0.65	GO:0010976	positive regulation of neuron projection development
0.63	GO:0070507	regulation of microtubule cytoskeleton organization
0.61	GO:0032956	regulation of actin cytoskeleton organization
0.60	GO:0043087	regulation of GTPase activity

0.85	GO:0005003	ephrin receptor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.65	GO:0005887	integral component of plasma membrane
0.63	GO:0005769	early endosome

sp|P29341|PABP1_MOUSE
Polyadenylate-binding protein 1
Search

PABPC1

0.60	Polyadenylate-binding protein 1-A

0.45	GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.44	GO:0045070	positive regulation of viral genome replication
0.40	GO:0007507	heart development
0.37	GO:0060212	negative regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.37	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.36	GO:0048255	mRNA stabilization
0.36	GO:0031047	gene silencing by RNA
0.35	GO:0006417	regulation of translation
0.35	GO:0006397	mRNA processing
0.34	GO:0043043	peptide biosynthetic process

0.59	GO:0003723	RNA binding
0.42	GO:0008022	protein C-terminus binding
0.37	GO:0031370	eukaryotic initiation factor 4G binding
0.36	GO:0043621	protein self-association

0.48	GO:0005737	cytoplasm
0.42	GO:0071013	catalytic step 2 spliceosome
0.41	GO:0035770	ribonucleoprotein granule
0.36	GO:0005844	polysome

sp|P29351|PTN6_MOUSE
Tyrosine-protein phosphatase non-receptor type 6
Search

PTPN6

0.61	Tyrosine-protein phosphatase non-receptor type

0.73	GO:0035335	peptidyl-tyrosine dephosphorylation
0.59	GO:0033277	abortive mitotic cell cycle
0.58	GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin
0.58	GO:0050859	negative regulation of B cell receptor signaling pathway
0.57	GO:0050860	negative regulation of T cell receptor signaling pathway
0.57	GO:0042267	natural killer cell mediated cytotoxicity
0.57	GO:0035855	megakaryocyte development
0.57	GO:0030220	platelet formation
0.57	GO:0033630	positive regulation of cell adhesion mediated by integrin
0.56	GO:0045577	regulation of B cell differentiation

0.74	GO:0004725	protein tyrosine phosphatase activity
0.59	GO:0140031	phosphorylation-dependent protein binding
0.58	GO:0019198	transmembrane receptor protein phosphatase activity
0.56	GO:0042169	SH2 domain binding
0.55	GO:0001784	phosphotyrosine residue binding
0.52	GO:0050839	cell adhesion molecule binding
0.52	GO:0017124	SH3 domain binding
0.52	GO:0019901	protein kinase binding
0.36	GO:0046703	natural killer cell lectin-like receptor binding

0.58	GO:0042105	alpha-beta T cell receptor complex
0.51	GO:0005911	cell-cell junction
0.50	GO:0005730	nucleolus
0.44	GO:0005737	cytoplasm
0.43	GO:0043234	protein complex
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0097708	intracellular vesicle
0.34	GO:0005654	nucleoplasm
0.33	GO:0012505	endomembrane system

0.74

GO:0004725

sp|P29352|PTN22_MOUSE
Tyrosine-protein phosphatase non-receptor type 22
Search

PTPN22

0.44	Tyrosine-protein phosphatase

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.64	GO:0035644	phosphoanandamide dephosphorylation
0.63	GO:1902523	positive regulation of protein K63-linked ubiquitination
0.63	GO:2000566	positive regulation of CD8-positive, alpha-beta T cell proliferation
0.63	GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
0.63	GO:0071663	positive regulation of granzyme B production
0.62	GO:0034157	positive regulation of toll-like receptor 7 signaling pathway
0.62	GO:1903753	negative regulation of p38MAPK cascade
0.62	GO:0071225	cellular response to muramyl dipeptide
0.62	GO:2000483	negative regulation of interleukin-8 secretion

0.74	GO:0004725	protein tyrosine phosphatase activity
0.61	GO:0017124	SH3 domain binding
0.55	GO:0019900	kinase binding
0.39	GO:0031625	ubiquitin protein ligase binding

0.54	GO:0009898	cytoplasmic side of plasma membrane
0.50	GO:0002102	podosome
0.47	GO:0005634	nucleus
0.44	GO:0005829	cytosol
0.39	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005925	focal adhesion
0.34	GO:0042995	cell projection
0.33	GO:0070013	intracellular organelle lumen
0.30	GO:0016021	integral component of membrane

0.74

GO:0004725

sp|P29387|GBB4_MOUSE
Guanine nucleotide-binding protein subunit beta-4
Search

GNB4

0.97	Guanine nucleotide-binding protein subunit beta-4

0.61	GO:0007165	signal transduction
0.42	GO:0060041	retina development in camera-type eye
0.41	GO:0050909	sensory perception of taste
0.41	GO:0008283	cell proliferation
0.38	GO:0010659	cardiac muscle cell apoptotic process
0.38	GO:0071377	cellular response to glucagon stimulus
0.38	GO:0070208	protein heterotrimerization
0.37	GO:0071456	cellular response to hypoxia
0.37	GO:0021762	substantia nigra development
0.37	GO:0007204	positive regulation of cytosolic calcium ion concentration

0.54	GO:0032403	protein complex binding
0.45	GO:0051020	GTPase binding
0.40	GO:0003924	GTPase activity
0.39	GO:0004871	signal transducer activity
0.39	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity
0.38	GO:0031702	type 1 angiotensin receptor binding
0.37	GO:0030507	spectrin binding
0.37	GO:0005246	calcium channel regulator activity

0.57	GO:0043209	myelin sheath
0.43	GO:0048471	perinuclear region of cytoplasm
0.42	GO:1905360	GTPase complex
0.42	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.42	GO:0001750	photoreceptor outer segment
0.40	GO:0005765	lysosomal membrane
0.40	GO:0044297	cell body
0.39	GO:0070062	extracellular exosome
0.39	GO:0098797	plasma membrane protein complex
0.38	GO:0060170	ciliary membrane

0.39

EC:3.1.4.39

GO:0047391

sp|P29391|FRIL1_MOUSE
Ferritin light chain 1
Search

FTL

0.55	Ferritin light chain

0.76	GO:0006879	cellular iron ion homeostasis
0.75	GO:0006826	iron ion transport
0.56	GO:0051238	sequestering of metal ion
0.53	GO:0051651	maintenance of location in cell
0.36	GO:0010288	response to lead ion
0.35	GO:0043312	neutrophil degranulation
0.33	GO:0055114	oxidation-reduction process

0.75	GO:0008199	ferric iron binding
0.38	GO:0042802	identical protein binding
0.37	GO:0016724	oxidoreductase activity, oxidizing metal ions, oxygen as acceptor
0.32	GO:0016874	ligase activity

0.49	GO:0070288	ferritin complex
0.41	GO:0044754	autolysosome
0.37	GO:0060205	cytoplasmic vesicle lumen
0.36	GO:0070062	extracellular exosome
0.35	GO:0005766	primary lysosome
0.35	GO:0030139	endocytic vesicle
0.35	GO:0005775	vacuolar lumen
0.34	GO:0030141	secretory granule
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.37

EC:1.16.3

GO:0016724

sp|P29416|HEXA_MOUSE
Beta-hexosaminidase subunit alpha
Search

HEXA

0.48	Beta-hexosaminidase subunit alpha

0.60	GO:0005975	carbohydrate metabolic process
0.56	GO:0006689	ganglioside catabolic process
0.56	GO:0050885	neuromuscular process controlling balance
0.55	GO:0050884	neuromuscular process controlling posture
0.55	GO:0042552	myelination
0.55	GO:0007040	lysosome organization
0.54	GO:0007628	adult walking behavior
0.54	GO:0019915	lipid storage
0.54	GO:0060395	SMAD protein signal transduction
0.53	GO:0007605	sensory perception of sound

0.79	GO:0004563	beta-N-acetylhexosaminidase activity
0.69	GO:0102148	N-acetyl-beta-D-galactosaminidase activity
0.41	GO:0008375	acetylglucosaminyltransferase activity
0.40	GO:0046982	protein heterodimerization activity
0.38	GO:0042803	protein homodimerization activity
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0003723	RNA binding
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.52	GO:0005764	lysosome
0.42	GO:0030141	secretory granule
0.39	GO:0005615	extracellular space
0.39	GO:0097223	sperm part
0.37	GO:1903561	extracellular vesicle
0.35	GO:0005775	vacuolar lumen
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.79

EC:3.2.1.52

GO:0004563

sp|P29452|CASP1_MOUSE
Caspase-1
Search

CASP1

0.87	Caspase 4, apoptosis-related cysteine peptidase

0.69	GO:0042981	regulation of apoptotic process
0.60	GO:0006508	proteolysis
0.56	GO:0012501	programmed cell death
0.55	GO:0050727	regulation of inflammatory response
0.55	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway
0.53	GO:0050718	positive regulation of interleukin-1 beta secretion
0.51	GO:0071260	cellular response to mechanical stimulus
0.50	GO:0051882	mitochondrial depolarization
0.50	GO:0050717	positive regulation of interleukin-1 alpha secretion
0.49	GO:0071310	cellular response to organic substance

0.75	GO:0004197	cysteine-type endopeptidase activity
0.54	GO:0050700	CARD domain binding
0.46	GO:0019900	kinase binding
0.45	GO:0042802	identical protein binding
0.37	GO:0097110	scaffold protein binding
0.36	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.34	GO:0002020	protease binding

0.62	GO:0097169	AIM2 inflammasome complex
0.62	GO:0072559	NLRP3 inflammasome complex
0.61	GO:0072557	IPAF inflammasome complex
0.57	GO:0072558	NLRP1 inflammasome complex
0.52	GO:0097179	protease inhibitor complex
0.43	GO:0005783	endoplasmic reticulum
0.42	GO:0005576	extracellular region
0.41	GO:0005739	mitochondrion
0.36	GO:0043005	neuron projection
0.35	GO:0005886	plasma membrane

0.75

EC:3.4.22

GO:0004197

sp|P29477|NOS2_MOUSE
Nitric oxide synthase, inducible
Search

NOS2

0.72	Nitric oxide synthase

0.83	GO:0006809	nitric oxide biosynthetic process
0.62	GO:0072604	interleukin-6 secretion
0.62	GO:0032310	prostaglandin secretion
0.61	GO:0072606	interleukin-8 secretion
0.61	GO:0018119	peptidyl-cysteine S-nitrosylation
0.59	GO:1900015	regulation of cytokine production involved in inflammatory response
0.57	GO:0009617	response to bacterium
0.56	GO:0071346	cellular response to interferon-gamma
0.55	GO:0050796	regulation of insulin secretion
0.55	GO:0098542	defense response to other organism

0.84	GO:0004517	nitric-oxide synthase activity
0.78	GO:0005516	calmodulin binding
0.69	GO:0010181	FMN binding
0.68	GO:0050661	NADP binding
0.65	GO:0050660	flavin adenine dinucleotide binding
0.62	GO:0020037	heme binding
0.62	GO:0005506	iron ion binding
0.60	GO:0034617	tetrahydrobiopterin binding
0.54	GO:0034618	arginine binding
0.51	GO:0042803	protein homodimerization activity

0.53	GO:0030863	cortical cytoskeleton
0.53	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005777	peroxisome
0.48	GO:0005829	cytosol
0.35	GO:0012506	vesicle membrane
0.34	GO:0005615	extracellular space
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.84

EC:1.14.13.39

GO:0004517

sp|P29533|VCAM1_MOUSE
Vascular cell adhesion protein 1
Search

0.64	Vascular cell adhesion molecule

0.77	GO:0098609	cell-cell adhesion
0.30	GO:0060711	labyrinthine layer development
0.30	GO:0051251	positive regulation of lymphocyte activation
0.30	GO:0050670	regulation of lymphocyte proliferation
0.30	GO:0071331	cellular response to hexose stimulus
0.30	GO:0040011	locomotion
0.30	GO:0016032	viral process
0.30	GO:0061032	visceral serous pericardium development
0.30	GO:0022409	positive regulation of cell-cell adhesion
0.30	GO:0007160	cell-matrix adhesion

0.30	GO:0050839	cell adhesion molecule binding
0.30	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
0.30	GO:0032403	protein complex binding
0.30	GO:0005102	receptor binding

0.30	GO:0045177	apical part of cell
0.30	GO:0043234	protein complex
0.30	GO:0044459	plasma membrane part
0.30	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane
0.30	GO:0005769	early endosome
0.30	GO:0120025	plasma membrane bounded cell projection
0.30	GO:0005783	endoplasmic reticulum
0.30	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0005794	Golgi apparatus

0.30

EC:1.4.3

GO:0016641

sp|P29594|CASP2_MOUSE
Caspase-2
Search

CASP2

0.96	Caspase 2, apoptosis-related cysteine peptidase

0.85	GO:0097194	execution phase of apoptosis
0.73	GO:0042981	regulation of apoptotic process
0.60	GO:0006508	proteolysis
0.60	GO:0035234	ectopic germ cell programmed cell death
0.60	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
0.59	GO:0038034	signal transduction in absence of ligand
0.58	GO:0071260	cellular response to mechanical stimulus
0.58	GO:0097191	extrinsic apoptotic signaling pathway
0.56	GO:0043068	positive regulation of programmed cell death
0.53	GO:0009967	positive regulation of signal transduction

0.85	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis
0.53	GO:0019904	protein domain specific binding
0.52	GO:0042802	identical protein binding
0.34	GO:0019899	enzyme binding

0.46	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P29595|NEDD8_MOUSE
NEDD8
Search

NEDD8

0.75	Neural precursor cell expressed, developmentally down-regulated 8

0.77	GO:0045116	protein neddylation
0.60	GO:0036099	female germ-line stem cell population maintenance
0.59	GO:0030431	sleep
0.59	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:2000736	regulation of stem cell differentiation
0.58	GO:0008589	regulation of smoothened signaling pathway
0.56	GO:0051438	regulation of ubiquitin-protein transferase activity
0.55	GO:0008104	protein localization
0.55	GO:0008283	cell proliferation
0.55	GO:0031647	regulation of protein stability

0.66	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0016791	phosphatase activity
0.39	GO:0031386	protein tag
0.37	GO:0004252	serine-type endopeptidase activity
0.36	GO:0004519	endonuclease activity

0.59	GO:0005654	nucleoplasm
0.58	GO:0005829	cytosol
0.42	GO:0070062	extracellular exosome

0.45

EC:3.1.3 EC:3.1.3.41

GO:0016791

sp|P29621|SPA3C_MOUSE
Serine protease inhibitor A3C
Search

0.73	Serine protease inhibitor

0.56	GO:0010951	negative regulation of endopeptidase activity
0.43	GO:0043434	response to peptide hormone
0.42	GO:0034097	response to cytokine
0.39	GO:0006954	inflammatory response
0.37	GO:0006508	proteolysis
0.37	GO:0006955	immune response
0.37	GO:0002576	platelet degranulation
0.36	GO:0034516	response to vitamin B6
0.35	GO:0071320	cellular response to cAMP
0.35	GO:0071385	cellular response to glucocorticoid stimulus

0.58	GO:0004867	serine-type endopeptidase inhibitor activity
0.38	GO:0008233	peptidase activity
0.36	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.35	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.73	GO:0005615	extracellular space
0.43	GO:0042583	chromaffin granule
0.37	GO:1903561	extracellular vesicle
0.36	GO:0034774	secretory granule lumen
0.35	GO:0005766	primary lysosome
0.35	GO:0031091	platelet alpha granule
0.35	GO:0005775	vacuolar lumen
0.34	GO:0042827	platelet dense granule
0.34	GO:0005634	nucleus
0.33	GO:0005794	Golgi apparatus

0.38

GO:0008233

sp|P29699|FETUA_MOUSE
Alpha-2-HS-glycoprotein
Search

AHSG

0.97

Fetuin-A

0.76	GO:0010951	negative regulation of endopeptidase activity
0.68	GO:0070168	negative regulation of biomineral tissue development
0.65	GO:0006953	acute-phase response
0.65	GO:0050766	positive regulation of phagocytosis
0.64	GO:0030279	negative regulation of ossification
0.64	GO:0030500	regulation of bone mineralization
0.61	GO:0050727	regulation of inflammatory response
0.61	GO:0001503	ossification
0.39	GO:0046627	negative regulation of insulin receptor signaling pathway
0.38	GO:0048731	system development

0.83	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.39	GO:0019210	kinase inhibitor activity
0.36	GO:0019887	protein kinase regulator activity
0.35	GO:0005515	protein binding

0.71	GO:0005615	extracellular space
0.57	GO:0031012	extracellular matrix
0.54	GO:0005794	Golgi apparatus
0.41	GO:0043230	extracellular organelle
0.39	GO:0031982	vesicle
0.36	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0005886	plasma membrane
0.34	GO:0043234	protein complex

sp|P29752|LALBA_MOUSE
Alpha-lactalbumin
Search

LALBA

0.91	Alpha-lactalbumin protein variant D

0.86	GO:0005989	lactose biosynthetic process
0.45	GO:0050830	defense response to Gram-positive bacterium
0.45	GO:0050829	defense response to Gram-negative bacterium
0.43	GO:1903494	response to dehydroepiandrosterone
0.43	GO:1903496	response to 11-deoxycorticosterone
0.43	GO:0016998	cell wall macromolecule catabolic process
0.42	GO:0032570	response to progesterone
0.42	GO:0032355	response to estradiol
0.34	GO:0006915	apoptotic process
0.34	GO:0007267	cell-cell signaling

0.86	GO:0004461	lactose synthase activity
0.68	GO:0005509	calcium ion binding
0.50	GO:0003796	lysozyme activity
0.35	GO:0005515	protein binding
0.32	GO:0003777	microtubule motor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005576	extracellular region
0.36	GO:0005815	microtubule organizing center
0.35	GO:0005796	Golgi lumen
0.34	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:2.4.1.22

GO:0004461

sp|P29754|AGTRA_MOUSE
Type-1A angiotensin II receptor
Search

AGTR1

0.97	Type-1 angiotensin II receptor

0.85	GO:0038166	angiotensin-activated signaling pathway
0.82	GO:0019229	regulation of vasoconstriction
0.42	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.42	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.41	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin
0.41	GO:0042756	drinking behavior
0.41	GO:0003071	renal system process involved in regulation of systemic arterial blood pressure
0.41	GO:0071549	cellular response to dexamethasone stimulus
0.41	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
0.40	GO:0045777	positive regulation of blood pressure

0.85	GO:0004945	angiotensin type II receptor activity
0.44	GO:0001596	angiotensin type I receptor activity
0.41	GO:0031711	bradykinin receptor binding
0.40	GO:0017046	peptide hormone binding
0.40	GO:0043621	protein self-association
0.38	GO:0031748	D1 dopamine receptor binding
0.37	GO:0001965	G-protein alpha-subunit binding
0.37	GO:0046982	protein heterodimerization activity
0.36	GO:0019901	protein kinase binding

0.40	GO:0031983	vesicle lumen
0.39	GO:0016323	basolateral plasma membrane
0.38	GO:0012506	vesicle membrane
0.37	GO:0055037	recycling endosome
0.37	GO:0030425	dendrite
0.36	GO:0031968	organelle outer membrane
0.35	GO:0005794	Golgi apparatus
0.34	GO:0005887	integral component of plasma membrane

sp|P29755|AGTRB_MOUSE
Type-1B angiotensin II receptor
Search

AGTR1

0.97	Type-1 angiotensin II receptor

0.85	GO:0038166	angiotensin-activated signaling pathway
0.82	GO:0019229	regulation of vasoconstriction
0.42	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.42	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.41	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin
0.41	GO:0042756	drinking behavior
0.41	GO:0003071	renal system process involved in regulation of systemic arterial blood pressure
0.41	GO:0071549	cellular response to dexamethasone stimulus
0.41	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
0.41	GO:0045777	positive regulation of blood pressure

0.85	GO:0004945	angiotensin type II receptor activity
0.44	GO:0001596	angiotensin type I receptor activity
0.41	GO:0031711	bradykinin receptor binding
0.40	GO:0017046	peptide hormone binding
0.40	GO:0043621	protein self-association
0.38	GO:0031748	D1 dopamine receptor binding
0.37	GO:0001965	G-protein alpha-subunit binding
0.37	GO:0046982	protein heterodimerization activity
0.36	GO:0019901	protein kinase binding

0.40	GO:0031983	vesicle lumen
0.39	GO:0016323	basolateral plasma membrane
0.38	GO:0012506	vesicle membrane
0.37	GO:0055037	recycling endosome
0.37	GO:0030425	dendrite
0.36	GO:0031968	organelle outer membrane
0.35	GO:0005794	Golgi apparatus
0.34	GO:0005887	integral component of plasma membrane

sp|P29758|OAT_MOUSE
Ornithine aminotransferase, mitochondrial
Search

OAT

0.54	Ornithine aminotransferaseserine-threonine

0.56	GO:0034214	protein hexamerization
0.38	GO:0055129	L-proline biosynthetic process
0.34	GO:0007601	visual perception
0.34	GO:0006591	ornithine metabolic process

0.83	GO:0004587	ornithine-oxo-acid transaminase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.43	GO:0042802	identical protein binding
0.34	GO:0003992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
0.33	GO:0008453	alanine-glyoxylate transaminase activity

0.48	GO:0005654	nucleoplasm
0.44	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.83	EC:2.6.1.13	GO:0004587
0.34	KEGG:R02283	GO:0003992

sp|P29788|VTNC_MOUSE
Vitronectin
Search

VTN

0.95	Serum-spreading factor

0.71	GO:0006955	immune response
0.69	GO:0006898	receptor-mediated endocytosis
0.65	GO:0061302	smooth muscle cell-matrix adhesion
0.63	GO:0014911	positive regulation of smooth muscle cell migration
0.62	GO:0033627	cell adhesion mediated by integrin
0.62	GO:0048709	oligodendrocyte differentiation
0.61	GO:0010811	positive regulation of cell-substrate adhesion
0.61	GO:0035987	endodermal cell differentiation
0.61	GO:0048260	positive regulation of receptor-mediated endocytosis
0.60	GO:0032092	positive regulation of protein binding

0.77	GO:0005044	scavenger receptor activity
0.75	GO:0001871	pattern binding
0.67	GO:0030246	carbohydrate binding
0.61	GO:0050840	extracellular matrix binding
0.60	GO:0005178	integrin binding
0.45	GO:0008201	heparin binding
0.43	GO:0005518	collagen binding
0.41	GO:0042802	identical protein binding
0.35	GO:0046872	metal ion binding
0.34	GO:0003677	DNA binding

0.56	GO:0005578	proteinaceous extracellular matrix
0.55	GO:0005615	extracellular space
0.52	GO:0005783	endoplasmic reticulum
0.45	GO:0005796	Golgi lumen
0.43	GO:0044420	extracellular matrix component
0.40	GO:1903561	extracellular vesicle
0.38	GO:0071062	alphav-beta3 integrin-vitronectin complex
0.34	GO:0005634	nucleus

sp|P29812|TYRP2_MOUSE
L-dopachrome tautomerase
Search

DCT

0.97	L-dopachrome tautomerase variant

0.60	GO:0006583	melanin biosynthetic process from tyrosine
0.59	GO:0021847	ventricular zone neuroblast division
0.56	GO:0002052	positive regulation of neuroblast proliferation
0.55	GO:0048066	developmental pigmentation
0.52	GO:0055114	oxidation-reduction process
0.50	GO:0048468	cell development
0.36	GO:0043438	acetoacetic acid metabolic process
0.36	GO:0048023	positive regulation of melanin biosynthetic process
0.35	GO:0032438	melanosome organization
0.35	GO:0008544	epidermis development

0.60	GO:0004167	dopachrome isomerase activity
0.54	GO:0016491	oxidoreductase activity
0.54	GO:0046872	metal ion binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0046982	protein heterodimerization activity

0.56	GO:0042470	melanosome
0.48	GO:0005829	cytosol
0.44	GO:0090741	pigment granule membrane
0.43	GO:0045009	chitosome
0.40	GO:0030659	cytoplasmic vesicle membrane
0.39	GO:0098805	whole membrane
0.35	GO:0045334	clathrin-coated endocytic vesicle
0.35	GO:0044440	endosomal part
0.30	GO:0016021	integral component of membrane

0.60	EC:5.3.3.12	GO:0004167
0.60	KEGG:R03673	GO:0004167

sp|P29974|CNGA1_MOUSE
cGMP-gated cation channel alpha-1
Search

CNGA1

0.97	Cyclic nucleotide-gated channel rod photoreceptor subunit alpha

0.73	GO:0007601	visual perception
0.60	GO:0034220	ion transmembrane transport
0.59	GO:0006812	cation transport
0.46	GO:0042391	regulation of membrane potential
0.36	GO:0050896	response to stimulus
0.35	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.35	GO:0051480	regulation of cytosolic calcium ion concentration
0.35	GO:0007283	spermatogenesis
0.33	GO:0023052	signaling
0.33	GO:0007154	cell communication

0.83	GO:0005221	intracellular cyclic nucleotide activated cation channel activity
0.51	GO:0005249	voltage-gated potassium channel activity
0.44	GO:0030553	cGMP binding
0.36	GO:0030552	cAMP binding
0.33	GO:0005515	protein binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0003700	DNA binding transcription factor activity

0.52	GO:0042622	photoreceptor outer segment membrane
0.42	GO:0005887	integral component of plasma membrane
0.37	GO:1902495	transmembrane transporter complex
0.35	GO:0043195	terminal bouton
0.33	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm

sp|P30051|TEAD1_MOUSE
Transcriptional enhancer factor TEF-1
Search

TEAD1

0.86	Transcriptional enhancer factor TEF-1

0.84	GO:0035329	hippo signaling
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0006351	transcription, DNA-templated
0.47	GO:0051254	positive regulation of RNA metabolic process
0.47	GO:0010557	positive regulation of macromolecule biosynthetic process
0.47	GO:0031328	positive regulation of cellular biosynthetic process
0.45	GO:0048568	embryonic organ development
0.40	GO:1902459	positive regulation of stem cell population maintenance

0.61	GO:0003700	DNA binding transcription factor activity
0.51	GO:0003677	DNA binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0001085	RNA polymerase II transcription factor binding
0.41	GO:0001223	transcription coactivator binding
0.40	GO:0001134	transcription factor activity, transcription factor recruiting
0.38	GO:0046982	protein heterodimerization activity

0.57	GO:0005634	nucleus
0.43	GO:0005667	transcription factor complex
0.43	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part

sp|P30115|GSTA3_MOUSE
Glutathione S-transferase A3
Search

0.43	Glutathione S-transferase alpha I

0.48	GO:0006749	glutathione metabolic process
0.46	GO:0060429	epithelium development
0.45	GO:0043651	linoleic acid metabolic process
0.44	GO:0046222	aflatoxin metabolic process
0.44	GO:0042221	response to chemical
0.43	GO:1901377	organic heteropentacyclic compound catabolic process
0.42	GO:0030154	cell differentiation
0.41	GO:0001823	mesonephros development
0.40	GO:1901687	glutathione derivative biosynthetic process
0.39	GO:0035295	tube development

0.76	GO:0004364	glutathione transferase activity
0.42	GO:0004602	glutathione peroxidase activity
0.40	GO:0043295	glutathione binding
0.34	GO:0008144	drug binding
0.34	GO:0005515	protein binding

0.46	GO:0005829	cytosol
0.43	GO:0070062	extracellular exosome
0.40	GO:0005640	nuclear outer membrane

0.76

EC:2.5.1.18

GO:0004364

sp|P30204|MSRE_MOUSE
Macrophage scavenger receptor types I and II
Search

MSR1

0.95	Macrophage scavenger receptor types I and II

0.71	GO:0006898	receptor-mediated endocytosis
0.61	GO:0097242	amyloid-beta clearance
0.61	GO:0010886	positive regulation of cholesterol storage
0.60	GO:0010744	positive regulation of macrophage derived foam cell differentiation
0.59	GO:0034381	plasma lipoprotein particle clearance
0.58	GO:0006911	phagocytosis, engulfment
0.57	GO:0030301	cholesterol transport
0.54	GO:0042953	lipoprotein transport
0.49	GO:0010629	negative regulation of gene expression
0.45	GO:0034755	iron ion transmembrane transport

0.80	GO:0005044	scavenger receptor activity
0.60	GO:0030169	low-density lipoprotein particle binding
0.58	GO:0001540	amyloid-beta binding
0.50	GO:0070287	ferritin receptor activity
0.36	GO:0051879	Hsp90 protein binding
0.36	GO:0005201	extracellular matrix structural constituent
0.36	GO:0030544	Hsp70 protein binding
0.35	GO:0042802	identical protein binding
0.35	GO:0019899	enzyme binding
0.33	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor

0.45	GO:0005886	plasma membrane
0.44	GO:0034362	low-density lipoprotein particle
0.44	GO:0005581	collagen trimer
0.42	GO:0009986	cell surface
0.37	GO:0031410	cytoplasmic vesicle
0.36	GO:0005604	basement membrane
0.36	GO:0012506	vesicle membrane
0.36	GO:0098552	side of membrane
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle

0.33

EC:1.4.3

GO:0016641

sp|P30275|KCRU_MOUSE
Creatine kinase U-type, mitochondrial
Search

0.91	Creatine kinase U-typeserine-threonine

0.57	GO:0016310	phosphorylation
0.47	GO:0032091	negative regulation of protein binding
0.45	GO:0043066	negative regulation of apoptotic process
0.37	GO:0006600	creatine metabolic process
0.36	GO:0021549	cerebellum development
0.36	GO:0007519	skeletal muscle tissue development
0.36	GO:0048565	digestive tract development
0.36	GO:0001822	kidney development

0.60	GO:0016301	kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor
0.35	GO:0005515	protein binding

0.46	GO:0043209	myelin sheath
0.43	GO:0005739	mitochondrion
0.39	GO:0019866	organelle inner membrane
0.38	GO:0070062	extracellular exosome
0.36	GO:0043204	perikaryon
0.30	GO:0044425	membrane part

0.40

EC:2.7.3

GO:0016775

sp|P30276|CCNB2_MOUSE
G2/mitotic-specific cyclin-B2
Search

CCNB2

0.97	Mitotic specific cyclin B2

0.55	GO:0043029	T cell homeostasis
0.55	GO:0048538	thymus development
0.54	GO:0001701	in utero embryonic development
0.51	GO:0040007	growth
0.46	GO:2000775	histone H3-S10 phosphorylation involved in chromosome condensation
0.46	GO:0031662	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle
0.45	GO:1905448	positive regulation of mitochondrial ATP synthesis coupled electron transport
0.44	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore
0.44	GO:0048146	positive regulation of fibroblast proliferation
0.44	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint

0.54	GO:0045296	cadherin binding
0.45	GO:0005113	patched binding
0.44	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity
0.42	GO:0044389	ubiquitin-like protein ligase binding
0.42	GO:0019901	protein kinase binding
0.38	GO:0016301	kinase activity
0.34	GO:0016874	ligase activity
0.34	GO:0060089	molecular transducer activity
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0140096	catalytic activity, acting on a protein

0.61	GO:0005634	nucleus
0.55	GO:0005813	centrosome
0.51	GO:0005829	cytosol
0.46	GO:0097125	cyclin B1-CDK1 complex
0.43	GO:0000940	condensed chromosome outer kinetochore
0.42	GO:0000922	spindle pole
0.41	GO:0005759	mitochondrial matrix
0.30	GO:0016020	membrane

0.34

GO:0016874

sp|P30280|CCND2_MOUSE
G1/S-specific cyclin-D2
Search

CCND2

0.94	G1/S-specific cyclin-D2

0.67	GO:0007049	cell cycle
0.60	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.59	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.59	GO:1901992	positive regulation of mitotic cell cycle phase transition
0.59	GO:0071481	cellular response to X-ray
0.57	GO:0007616	long-term memory
0.57	GO:1902808	positive regulation of cell cycle G1/S phase transition
0.56	GO:0008284	positive regulation of cell proliferation
0.56	GO:0008344	adult locomotory behavior
0.53	GO:0043066	negative regulation of apoptotic process

0.56	GO:0019901	protein kinase binding
0.46	GO:0070064	proline-rich region binding
0.45	GO:0042826	histone deacetylase binding
0.44	GO:0003714	transcription corepressor activity
0.44	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.42	GO:0008134	transcription factor binding
0.39	GO:0004672	protein kinase activity
0.35	GO:0032403	protein complex binding
0.33	GO:0060089	molecular transducer activity
0.32	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.60	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.51	GO:0070013	intracellular organelle lumen
0.50	GO:0000785	chromatin
0.48	GO:0005829	cytosol
0.48	GO:0012505	endomembrane system
0.45	GO:0031967	organelle envelope
0.45	GO:0031090	organelle membrane
0.44	GO:0017053	transcriptional repressor complex
0.43	GO:0005923	bicellular tight junction

0.44

GO:0016538

sp|P30282|CCND3_MOUSE
G1/S-specific cyclin-D3
Search

CCND3

0.88	Cyclin D3 (Predicted)

0.67	GO:0007049	cell cycle
0.60	GO:0042098	T cell proliferation
0.60	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.59	GO:0046626	regulation of insulin receptor signaling pathway
0.57	GO:0000122	negative regulation of transcription by RNA polymerase II
0.56	GO:0042127	regulation of cell proliferation
0.47	GO:0007165	signal transduction
0.44	GO:0070141	response to UV-A
0.43	GO:0044783	G1 DNA damage checkpoint
0.43	GO:2000045	regulation of G1/S transition of mitotic cell cycle

0.59	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.57	GO:0019901	protein kinase binding
0.42	GO:0070064	proline-rich region binding
0.41	GO:0042826	histone deacetylase binding
0.41	GO:0003714	transcription corepressor activity
0.41	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.39	GO:0008134	transcription factor binding
0.36	GO:0032403	protein complex binding

0.61	GO:0005634	nucleus
0.59	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.41	GO:0017053	transcriptional repressor complex
0.41	GO:0005737	cytoplasm
0.41	GO:0005923	bicellular tight junction
0.39	GO:0070013	intracellular organelle lumen
0.37	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.59

EC:2.7.11.22

GO:0004693

sp|P30285|CDK4_MOUSE
Cyclin-dependent kinase 4
Search

CDK4

0.80	Cyclin dependent protein kinase

0.63	GO:0006468	protein phosphorylation
0.59	GO:0042127	regulation of cell proliferation
0.58	GO:0051726	regulation of cell cycle
0.57	GO:0043697	cell dedifferentiation
0.56	GO:1904628	cellular response to phorbol 13-acetate 12-myristate
0.56	GO:1904636	response to ionomycin
0.55	GO:0071362	cellular response to ether
0.55	GO:0000082	G1/S transition of mitotic cell cycle
0.53	GO:0071353	cellular response to interleukin-4
0.53	GO:0060612	adipose tissue development

0.67	GO:0004674	protein serine/threonine kinase activity
0.65	GO:0097472	cyclin-dependent protein kinase activity
0.55	GO:0030332	cyclin binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.41	GO:0098770	FBXO family protein binding
0.39	GO:0032403	protein complex binding
0.36	GO:0030234	enzyme regulator activity

0.56	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.50	GO:0005923	bicellular tight junction
0.50	GO:0031965	nuclear membrane
0.48	GO:0005667	transcription factor complex
0.47	GO:0005730	nucleolus
0.47	GO:0005829	cytosol
0.46	GO:0000785	chromatin
0.39	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0001726	ruffle
0.38	GO:0005654	nucleoplasm

0.67

GO:0004674

sp|P30306|MPIP2_MOUSE
M-phase inducer phosphatase 2
Search

CDC25B

0.90	Cell division cycle 25 homolog B

0.84	GO:1902751	positive regulation of cell cycle G2/M phase transition
0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.65	GO:0007144	female meiosis I
0.64	GO:0045931	positive regulation of mitotic cell cycle
0.64	GO:0001556	oocyte maturation
0.62	GO:0032467	positive regulation of cytokinesis
0.58	GO:0045860	positive regulation of protein kinase activity
0.49	GO:0006468	protein phosphorylation
0.49	GO:0009794	regulation of mitotic cell cycle, embryonic
0.48	GO:0051301	cell division

0.75	GO:0004725	protein tyrosine phosphatase activity
0.62	GO:0019901	protein kinase binding
0.45	GO:0051087	chaperone binding

0.59	GO:0000922	spindle pole
0.58	GO:0005813	centrosome
0.50	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm

0.75

GO:0004725

sp|P30355|AL5AP_MOUSE
Arachidonate 5-lipoxygenase-activating protein
Search

ALOX5AP

0.97	Arachidonate 5-lipoxygenase-activating protein isoform 1

0.86	GO:0006691	leukotriene metabolic process
0.73	GO:0043085	positive regulation of catalytic activity
0.66	GO:0002540	leukotriene production involved in inflammatory response
0.65	GO:0046456	icosanoid biosynthetic process
0.44	GO:0001525	angiogenesis
0.42	GO:0019372	lipoxygenase pathway
0.42	GO:0070207	protein homotrimerization
0.40	GO:0002675	positive regulation of acute inflammatory response
0.40	GO:0071277	cellular response to calcium ion
0.37	GO:2001300	lipoxin metabolic process

0.75	GO:0008047	enzyme activator activity
0.54	GO:0004464	leukotriene-C4 synthase activity
0.49	GO:0050544	arachidonic acid binding
0.49	GO:0004364	glutathione transferase activity
0.49	GO:0004602	glutathione peroxidase activity
0.41	GO:0004051	arachidonate 5-lipoxygenase activity
0.40	GO:0047485	protein N-terminus binding
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0046982	protein heterodimerization activity
0.37	GO:0019899	enzyme binding

0.49	GO:0005634	nucleus
0.47	GO:0005783	endoplasmic reticulum
0.43	GO:0031967	organelle envelope
0.43	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.42	GO:0031984	organelle subcompartment
0.40	GO:0031090	organelle membrane
0.37	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.54	EC:4.4.1.20	GO:0004464
0.54	KEGG:R03059	GO:0004464

sp|P30412|PPIC_MOUSE
Peptidyl-prolyl cis-trans isomerase C
Search

PPIC

0.47	Peptidyl-prolyl cis-trans isomerase C

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.68	GO:0006457	protein folding
0.47	GO:0044829	positive regulation by host of viral genome replication
0.46	GO:0040018	positive regulation of multicellular organism growth
0.45	GO:0060348	bone development
0.44	GO:0050821	protein stabilization
0.36	GO:1901873	regulation of post-translational protein modification
0.34	GO:0051169	nuclear transport

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.57	GO:0016018	cyclosporin A binding
0.43	GO:0070063	RNA polymerase binding
0.42	GO:0032403	protein complex binding
0.33	GO:0051082	unfolded protein binding
0.33	GO:0003723	RNA binding

0.47	GO:0034663	endoplasmic reticulum chaperone complex
0.44	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005634	nucleus
0.38	GO:0042470	melanosome
0.38	GO:0005788	endoplasmic reticulum lumen
0.38	GO:0005790	smooth endoplasmic reticulum
0.38	GO:0070062	extracellular exosome
0.35	GO:0005925	focal adhesion
0.30	GO:0016020	membrane

0.72

GO:0003755

sp|P30415|NKTR_MOUSE
NK-tumor recognition protein
Search

NKTR

0.90	Natural killer cell triggering receptor

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.65	GO:0006457	protein folding

0.72

GO:0003755

peptidyl-prolyl cis-trans isomerase activity

0.59	GO:0005654	nucleoplasm
0.58	GO:0005829	cytosol
0.52	GO:0005739	mitochondrion
0.48	GO:0005886	plasma membrane

0.72

GO:0003755

sp|P30416|FKBP4_MOUSE
Peptidyl-prolyl cis-trans isomerase FKBP4
Search

FKBP4

0.52	Peptidyl-prolyl cis-trans isomerase FKBP4

0.86	GO:0006463	steroid hormone receptor complex assembly
0.85	GO:0031111	negative regulation of microtubule polymerization or depolymerization
0.85	GO:0010977	negative regulation of neuron projection development
0.83	GO:0007566	embryo implantation
0.82	GO:0030521	androgen receptor signaling pathway
0.82	GO:0030850	prostate gland development
0.79	GO:0061077	chaperone-mediated protein folding
0.79	GO:0046661	male sex differentiation
0.77	GO:0031503	protein complex localization
0.74	GO:0031113	regulation of microtubule polymerization

0.85	GO:0048156	tau protein binding
0.85	GO:0005528	FK506 binding
0.85	GO:0035259	glucocorticoid receptor binding
0.81	GO:0032767	copper-dependent protein binding
0.79	GO:0051219	phosphoprotein binding
0.78	GO:0031072	heat shock protein binding
0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.62	GO:0032550	purine ribonucleoside binding
0.62	GO:0019001	guanyl nucleotide binding
0.52	GO:0030674	protein binding, bridging

0.86	GO:0044295	axonal growth cone
0.73	GO:0005874	microtubule
0.70	GO:0043025	neuronal cell body
0.69	GO:0048471	perinuclear region of cytoplasm
0.69	GO:0005829	cytosol
0.66	GO:0005654	nucleoplasm
0.63	GO:0070062	extracellular exosome
0.61	GO:0005739	mitochondrion
0.53	GO:0043234	protein complex

0.72

GO:0003755

sp|P30545|ADA2B_MOUSE
Alpha-2B adrenergic receptor
Search

ADRA2B

0.84	LOW QUALITY PROTEIN: alpha-2B adrenergic receptor

0.85	GO:0071875	adrenergic receptor signaling pathway
0.85	GO:0006940	regulation of smooth muscle contraction
0.85	GO:0019229	regulation of vasoconstriction
0.85	GO:0030168	platelet activation
0.52	GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
0.50	GO:0032148	activation of protein kinase B activity
0.48	GO:0045666	positive regulation of neuron differentiation
0.47	GO:0043410	positive regulation of MAPK cascade
0.42	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.40	GO:0007267	cell-cell signaling

0.86	GO:0004938	alpha2-adrenergic receptor activity
0.51	GO:0051379	epinephrine binding
0.34	GO:0005515	protein binding
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0008270	zinc ion binding

0.51	GO:0005886	plasma membrane
0.34	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.33

GO:0004222

sp|P30548|NK1R_MOUSE
Substance-P receptor
Search

TACR1

0.97	Neuromedin-K receptor

0.85	GO:0007217	tachykinin receptor signaling pathway
0.60	GO:1902093	positive regulation of flagellated sperm motility
0.55	GO:0070472	regulation of uterine smooth muscle contraction
0.54	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.54	GO:0048265	response to pain
0.48	GO:0045987	positive regulation of smooth muscle contraction
0.44	GO:0007268	chemical synaptic transmission
0.42	GO:0072347	response to anesthetic
0.42	GO:0043279	response to alkaloid
0.41	GO:0060359	response to ammonium ion

0.86	GO:0004995	tachykinin receptor activity
0.34	GO:0050254	rhodopsin kinase activity
0.33	GO:0005515	protein binding

0.59	GO:0097225	sperm midpiece
0.58	GO:0061827	sperm head
0.56	GO:0005886	plasma membrane
0.38	GO:0030425	dendrite
0.38	GO:0044297	cell body
0.37	GO:0009986	cell surface
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.34

GO:0050254

sp|P30549|NK2R_MOUSE
Substance-K receptor
Search

TACR2

0.92	Neuromedin-K receptor

0.85	GO:0007217	tachykinin receptor signaling pathway
0.66	GO:1902093	positive regulation of flagellated sperm motility
0.61	GO:0070472	regulation of uterine smooth muscle contraction
0.50	GO:0045987	positive regulation of smooth muscle contraction
0.44	GO:0007267	cell-cell signaling
0.43	GO:0035106	operant conditioning
0.43	GO:0032224	positive regulation of synaptic transmission, cholinergic
0.43	GO:0043117	positive regulation of vascular permeability
0.42	GO:0033685	negative regulation of luteinizing hormone secretion
0.42	GO:0051602	response to electrical stimulus

0.86	GO:0004995	tachykinin receptor activity
0.34	GO:0050254	rhodopsin kinase activity
0.34	GO:0005515	protein binding

0.64	GO:0097225	sperm midpiece
0.61	GO:0061827	sperm head
0.56	GO:0005886	plasma membrane
0.38	GO:0030425	dendrite
0.38	GO:0044297	cell body
0.36	GO:0031252	cell leading edge
0.35	GO:0009986	cell surface
0.34	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.34

GO:0050254

sp|P30554|MAS_MOUSE
Proto-oncogene Mas
Search

MAS1

0.94	MAS1 proto-oncogene, G protein-coupled receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.69	GO:0070528	protein kinase C signaling
0.67	GO:0007250	activation of NF-kappaB-inducing kinase activity
0.66	GO:1904385	cellular response to angiotensin
0.62	GO:0050727	regulation of inflammatory response
0.40	GO:0060732	positive regulation of inositol phosphate biosynthetic process
0.40	GO:0034698	response to gonadotropin
0.39	GO:0014823	response to activity
0.39	GO:0021766	hippocampus development
0.39	GO:0045740	positive regulation of DNA replication

0.72	GO:0004930	G-protein coupled receptor activity
0.61	GO:0042277	peptide binding
0.61	GO:0001653	peptide receptor activity
0.39	GO:0042562	hormone binding

0.47	GO:0005886	plasma membrane
0.40	GO:0005622	intracellular
0.37	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|P30557|PE2R3_MOUSE
Prostaglandin E2 receptor EP3 subtype
Search

PTGER3

0.97	Prostaglandin E receptor 3

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0060455	negative regulation of gastric acid secretion
0.52	GO:0014827	intestine smooth muscle contraction
0.41	GO:0031622	positive regulation of fever generation
0.39	GO:0035810	positive regulation of urine volume
0.39	GO:0001660	fever generation
0.38	GO:0015701	bicarbonate transport
0.38	GO:0032496	response to lipopolysaccharide
0.38	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.37	GO:1990767	prostaglandin receptor internalization

0.85	GO:0004957	prostaglandin E receptor activity
0.49	GO:0004960	thromboxane receptor activity
0.35	GO:0005515	protein binding
0.33	GO:0004958	prostaglandin F receptor activity
0.32	GO:0046872	metal ion binding

0.37	GO:1990769	proximal neuron projection
0.36	GO:0005635	nuclear envelope
0.36	GO:0005886	plasma membrane
0.36	GO:0005903	brush border
0.35	GO:0043025	neuronal cell body
0.35	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0009986	cell surface
0.33	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

sp|P30558|PAR1_MOUSE
Proteinase-activated receptor 1
Search

F2R

0.96	Coagulation factor II thrombin receptor

0.85	GO:0070493	thrombin-activated receptor signaling pathway
0.82	GO:0007596	blood coagulation
0.70	GO:1900133	regulation of renin secretion into blood stream
0.69	GO:0035025	positive regulation of Rho protein signal transduction
0.67	GO:2000484	positive regulation of interleukin-8 secretion
0.66	GO:2000778	positive regulation of interleukin-6 secretion
0.66	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.66	GO:1903524	positive regulation of blood circulation
0.65	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.65	GO:0030193	regulation of blood coagulation

0.85	GO:0015057	thrombin-activated receptor activity
0.69	GO:0031681	G-protein beta-subunit binding
0.67	GO:0001965	G-protein alpha-subunit binding
0.51	GO:0005102	receptor binding
0.38	GO:0032795	heterotrimeric G-protein binding
0.37	GO:0004994	somatostatin receptor activity
0.33	GO:0008233	peptidase activity

0.63	GO:0031094	platelet dense tubular network
0.59	GO:0005769	early endosome
0.59	GO:0005901	caveola
0.55	GO:0005770	late endosome
0.52	GO:0009986	cell surface
0.51	GO:0031594	neuromuscular junction
0.48	GO:0045211	postsynaptic membrane
0.48	GO:0031143	pseudopodium
0.47	GO:0005887	integral component of plasma membrane
0.35	GO:0005794	Golgi apparatus

0.33

GO:0008233

sp|P30561|AHR_MOUSE
Aryl hydrocarbon receptor
Search

AHR

0.74	Aryl hydrocarbon receptor

0.79	GO:0030522	intracellular receptor signaling pathway
0.77	GO:0009410	response to xenobiotic stimulus
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0006351	transcription, DNA-templated
0.55	GO:0014070	response to organic cyclic compound
0.52	GO:0051254	positive regulation of RNA metabolic process
0.52	GO:0010557	positive regulation of macromolecule biosynthetic process
0.52	GO:0031328	positive regulation of cellular biosynthetic process

0.85	GO:0004874	aryl hydrocarbon receptor activity
0.65	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0070888	E-box binding
0.50	GO:0001094	TFIID-class transcription factor binding
0.49	GO:0001223	transcription coactivator binding
0.49	GO:0051879	Hsp90 protein binding
0.48	GO:0035326	enhancer binding
0.47	GO:0017025	TBP-class protein binding
0.38	GO:0051087	chaperone binding

0.85	GO:0034751	aryl hydrocarbon receptor complex
0.58	GO:0005634	nucleus
0.46	GO:0005667	transcription factor complex
0.40	GO:0005737	cytoplasm
0.36	GO:0044446	intracellular organelle part
0.34	GO:0070013	intracellular organelle lumen
0.30	GO:0016020	membrane

sp|P30658|CBX2_MOUSE
Chromobox protein homolog 2
Search

CBX2

0.96	Chromobox protein like protein 2

0.68	GO:0045137	development of primary sexual characteristics
0.66	GO:0000122	negative regulation of transcription by RNA polymerase II
0.40	GO:0016569	covalent chromatin modification
0.38	GO:0016925	protein sumoylation
0.37	GO:0030154	cell differentiation
0.36	GO:0006351	transcription, DNA-templated

0.68	GO:0140034	methylation-dependent protein binding
0.65	GO:0042393	histone binding
0.63	GO:0003682	chromatin binding
0.40	GO:0032183	SUMO binding
0.39	GO:0051219	phosphoprotein binding
0.38	GO:0003727	single-stranded RNA binding
0.38	GO:0044212	transcription regulatory region DNA binding
0.36	GO:0019899	enzyme binding
0.33	GO:0019789	SUMO transferase activity

0.73	GO:0035102	PRC1 complex
0.68	GO:0000791	euchromatin
0.66	GO:0000792	heterochromatin
0.60	GO:0005654	nucleoplasm

sp|P30677|GNA14_MOUSE
Guanine nucleotide-binding protein subunit alpha-14
Search

GNA14

0.80	G protein subunit alpha q

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.59	GO:0045634	regulation of melanocyte differentiation
0.57	GO:0001508	action potential
0.56	GO:0048066	developmental pigmentation
0.55	GO:0007603	phototransduction, visible light
0.54	GO:0009649	entrainment of circadian clock
0.54	GO:0001501	skeletal system development
0.53	GO:0007507	heart development
0.53	GO:0095500	acetylcholine receptor signaling pathway
0.52	GO:0042711	maternal behavior

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.81	GO:0001664	G-protein coupled receptor binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0005096	GTPase activator activity
0.39	GO:0002046	opsin binding

0.57	GO:1905360	GTPase complex
0.56	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.53	GO:0001750	photoreceptor outer segment
0.49	GO:0098797	plasma membrane protein complex
0.48	GO:0030425	dendrite
0.48	GO:0044297	cell body
0.39	GO:0097232	lamellar body membrane
0.38	GO:0070062	extracellular exosome

sp|P30678|GNA15_MOUSE
Guanine nucleotide-binding protein subunit alpha-15
Search

GNA15

0.85	Guanine nucleotide binding protein, q polypeptide

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.53	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.37	GO:0010033	response to organic substance
0.37	GO:1903831	signal transduction involved in cellular response to ammonium ion
0.37	GO:1901700	response to oxygen-containing compound
0.37	GO:0071495	cellular response to endogenous stimulus
0.36	GO:0035690	cellular response to drug
0.36	GO:0007202	activation of phospholipase C activity
0.36	GO:0030168	platelet activation
0.35	GO:0007264	small GTPase mediated signal transduction

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.76	GO:0001664	G-protein coupled receptor binding
0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.64	GO:0004871	signal transducer activity
0.35	GO:0046872	metal ion binding
0.35	GO:0005095	GTPase inhibitor activity
0.34	GO:0016247	channel regulator activity

0.50	GO:1905360	GTPase complex
0.49	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.44	GO:0098797	plasma membrane protein complex
0.34	GO:0001750	photoreceptor outer segment
0.34	GO:0055044	symplast
0.34	GO:0005911	cell-cell junction
0.34	GO:0012505	endomembrane system
0.33	GO:0031984	organelle subcompartment
0.33	GO:0031410	cytoplasmic vesicle
0.32	GO:0043231	intracellular membrane-bounded organelle

sp|P30681|HMGB2_MOUSE
High mobility group protein B2
Search

HMGB2

0.88	High mobility group box 2

0.68	GO:0002437	inflammatory response to antigenic stimulus
0.63	GO:0050830	defense response to Gram-positive bacterium
0.62	GO:0050829	defense response to Gram-negative bacterium
0.61	GO:0032496	response to lipopolysaccharide
0.60	GO:0072091	regulation of stem cell proliferation
0.60	GO:0032392	DNA geometric change
0.57	GO:0045595	regulation of cell differentiation
0.57	GO:2000026	regulation of multicellular organismal development
0.56	GO:0043388	positive regulation of DNA binding
0.56	GO:0001938	positive regulation of endothelial cell proliferation

0.75	GO:0008301	DNA binding, bending
0.72	GO:0097100	supercoiled DNA binding
0.72	GO:0000400	four-way junction DNA binding
0.62	GO:0000405	bubble DNA binding
0.60	GO:0001158	enhancer sequence-specific DNA binding
0.55	GO:0008134	transcription factor binding
0.55	GO:0050786	RAGE receptor binding
0.54	GO:0042056	chemoattractant activity
0.50	GO:0003684	damaged DNA binding
0.47	GO:0019904	protein domain specific binding

0.61	GO:0005634	nucleus
0.57	GO:0005615	extracellular space
0.55	GO:0000785	chromatin
0.52	GO:0070013	intracellular organelle lumen
0.52	GO:0000793	condensed chromosome
0.50	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0035868	alphav-beta3 integrin-HMGB1 complex
0.42	GO:0017053	transcriptional repressor complex
0.42	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.41	GO:0009986	cell surface

0.38

EC:4

GO:0016829

sp|P30728|DRD3_MOUSE
D(3) dopamine receptor
Search

DRD3

0.91	Dopamine receptor 3

0.84	GO:0007212	dopamine receptor signaling pathway
0.80	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.65	GO:0060160	negative regulation of dopamine receptor signaling pathway
0.64	GO:0048148	behavioral response to cocaine
0.63	GO:0060134	prepulse inhibition
0.63	GO:0034776	response to histamine
0.63	GO:0014059	regulation of dopamine secretion
0.63	GO:0043278	response to morphine
0.63	GO:0001975	response to amphetamine
0.62	GO:0045776	negative regulation of blood pressure

0.85	GO:0004952	dopamine neurotransmitter receptor activity
0.53	GO:0035240	dopamine binding
0.43	GO:0042802	identical protein binding
0.43	GO:0031748	D1 dopamine receptor binding
0.42	GO:0004935	adrenergic receptor activity
0.40	GO:0019904	protein domain specific binding
0.37	GO:0035255	ionotropic glutamate receptor binding
0.35	GO:0046982	protein heterodimerization activity
0.35	GO:0015459	potassium channel regulator activity

0.65	GO:0005887	integral component of plasma membrane
0.46	GO:0060170	ciliary membrane
0.45	GO:0097730	non-motile cilium
0.45	GO:0030425	dendrite
0.45	GO:0030424	axon
0.43	GO:0031410	cytoplasmic vesicle
0.41	GO:0098793	presynapse
0.40	GO:0045177	apical part of cell
0.40	GO:0012506	vesicle membrane
0.39	GO:0098805	whole membrane

sp|P30730|LSHR_MOUSE
Lutropin-choriogonadotropic hormone receptor
Search

LHCGR

0.80	Lutropin-choriogonadotropic hormone receptor

0.80	GO:0042700	luteinizing hormone signaling pathway
0.68	GO:0001541	ovarian follicle development
0.63	GO:0071371	cellular response to gonadotropin stimulus
0.63	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process
0.63	GO:0046544	development of secondary male sexual characteristics
0.62	GO:0007190	activation of adenylate cyclase activity
0.62	GO:0060065	uterus development
0.61	GO:0008584	male gonad development
0.61	GO:0090030	regulation of steroid hormone biosynthetic process
0.60	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway

0.84	GO:0016500	protein-hormone receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.64	GO:0038106	choriogonadotropin hormone binding
0.47	GO:0001653	peptide receptor activity
0.37	GO:0017046	peptide hormone binding
0.36	GO:0051117	ATPase binding
0.35	GO:0042803	protein homodimerization activity

0.53	GO:0005886	plasma membrane
0.40	GO:0009986	cell surface
0.38	GO:0005622	intracellular
0.37	GO:0031982	vesicle
0.36	GO:0012505	endomembrane system
0.36	GO:0043235	receptor complex
0.35	GO:0098552	side of membrane
0.35	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

sp|P30731|GPR83_MOUSE
Probable G-protein coupled receptor 83
Search

GPR83

0.85	G protein-coupled receptor 83

0.79	GO:0007218	neuropeptide signaling pathway
0.53	GO:0051384	response to glucocorticoid
0.33	GO:0006302	double-strand break repair
0.32	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.84	GO:0004983	neuropeptide Y receptor activity
0.33	GO:0030145	manganese ion binding
0.33	GO:0004519	endonuclease activity

0.52	GO:0097730	non-motile cilium
0.34	GO:0005886	plasma membrane
0.32	GO:0005634	nucleus
0.30	GO:0044425	membrane part

sp|P30873|SSR1_MOUSE
Somatostatin receptor type 1
Search

SSTR1

0.97	Somatostatin receptor type 1 subtype A

0.86	GO:0038169	somatostatin receptor signaling pathway
0.77	GO:0009755	hormone-mediated signaling pathway
0.55	GO:0007218	neuropeptide signaling pathway
0.54	GO:1990823	response to leukemia inhibitory factor
0.52	GO:0071345	cellular response to cytokine stimulus
0.51	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.51	GO:0007215	glutamate receptor signaling pathway
0.50	GO:0071392	cellular response to estradiol stimulus
0.48	GO:0008285	negative regulation of cell proliferation
0.44	GO:0071385	cellular response to glucocorticoid stimulus

0.86	GO:0004994	somatostatin receptor activity
0.53	GO:0042923	neuropeptide binding
0.42	GO:0030165	PDZ domain binding
0.36	GO:0046982	protein heterodimerization activity
0.36	GO:0017046	peptide hormone binding
0.35	GO:0042803	protein homodimerization activity
0.33	GO:0004985	opioid receptor activity

0.48	GO:0043005	neuron projection
0.45	GO:0005886	plasma membrane
0.39	GO:0005829	cytosol
0.36	GO:0043235	receptor complex
0.30	GO:0016021	integral component of membrane

sp|P30875|SSR2_MOUSE
Somatostatin receptor type 2
Search

SSTR2

0.97	Somatostatin receptor type 2

0.85	GO:0038169	somatostatin receptor signaling pathway
0.76	GO:0009755	hormone-mediated signaling pathway
0.56	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.53	GO:0007218	neuropeptide signaling pathway
0.51	GO:0071385	cellular response to glucocorticoid stimulus
0.50	GO:0071392	cellular response to estradiol stimulus
0.48	GO:0008285	negative regulation of cell proliferation
0.40	GO:0030432	peristalsis
0.39	GO:0021549	cerebellum development
0.38	GO:0006937	regulation of muscle contraction

0.85	GO:0004994	somatostatin receptor activity
0.56	GO:0030165	PDZ domain binding
0.51	GO:0042923	neuropeptide binding
0.35	GO:0017046	peptide hormone binding
0.34	GO:0046982	protein heterodimerization activity

0.48	GO:0005829	cytosol
0.47	GO:0043005	neuron projection
0.43	GO:0005887	integral component of plasma membrane
0.35	GO:0098802	plasma membrane receptor complex

sp|P30882|CCL5_MOUSE
C-C motif chemokine 5
Search

CCL5

0.75	C-C motif chemokine

0.82	GO:0070098	chemokine-mediated signaling pathway
0.82	GO:0060326	cell chemotaxis
0.79	GO:0006954	inflammatory response
0.75	GO:0009615	response to virus
0.74	GO:0006955	immune response
0.73	GO:0010469	regulation of receptor activity
0.63	GO:0010820	positive regulation of T cell chemotaxis
0.62	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin
0.62	GO:2000503	positive regulation of natural killer cell chemotaxis
0.62	GO:0031584	activation of phospholipase D activity

0.86	GO:0031729	CCR4 chemokine receptor binding
0.86	GO:0031726	CCR1 chemokine receptor binding
0.86	GO:0031730	CCR5 chemokine receptor binding
0.84	GO:0008009	chemokine activity
0.63	GO:0046817	chemokine receptor antagonist activity
0.62	GO:0016004	phospholipase activator activity
0.61	GO:0030298	receptor signaling protein tyrosine kinase activator activity
0.60	GO:0042056	chemoattractant activity
0.58	GO:0043621	protein self-association
0.56	GO:0004435	phosphatidylinositol phospholipase C activity

0.73	GO:0005615	extracellular space
0.39	GO:0005737	cytoplasm

0.56	EC:3.1.4.11	GO:0004435
0.56	KEGG:R03435	GO:0004435

sp|P30933|SVS5_MOUSE
Seminal vesicle secretory protein 5
Search

SVS5

0.97	Seminal vesicle secretory protein 5

0.73

GO:0005615

extracellular space

sp|P30935|SSR3_MOUSE
Somatostatin receptor type 3
Search

SSTR3

0.95	Type-three somatostatin receptor subtype B

0.86	GO:0038169	somatostatin receptor signaling pathway
0.77	GO:0009755	hormone-mediated signaling pathway
0.49	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.49	GO:0090276	regulation of peptide hormone secretion
0.49	GO:0032467	positive regulation of cytokinesis
0.48	GO:0007268	chemical synaptic transmission
0.47	GO:0042593	glucose homeostasis
0.47	GO:0050708	regulation of protein secretion
0.46	GO:0007218	neuropeptide signaling pathway
0.46	GO:0071385	cellular response to glucocorticoid stimulus

0.86	GO:0004994	somatostatin receptor activity
0.52	GO:0042923	neuropeptide binding
0.50	GO:0005102	receptor binding
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0060170	ciliary membrane
0.55	GO:0097730	non-motile cilium
0.48	GO:0043005	neuron projection
0.44	GO:0005887	integral component of plasma membrane
0.36	GO:0005581	collagen trimer
0.34	GO:0005576	extracellular region
0.34	GO:0005737	cytoplasm

sp|P30966|5HT5A_MOUSE
5-hydroxytryptamine receptor 5A
Search

HTR5A

0.97	5-hydroxytryptamine (Serotonin) receptor 5A, G protein-coupled

0.83	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.58	GO:0019933	cAMP-mediated signaling
0.49	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.41	GO:0032355	response to estradiol
0.41	GO:0021766	hippocampus development

0.83	GO:0099589	serotonin receptor activity
0.80	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.80	GO:0008227	G-protein coupled amine receptor activity
0.51	GO:0051378	serotonin binding
0.33	GO:0008144	drug binding

0.62	GO:0005887	integral component of plasma membrane
0.41	GO:0043204	perikaryon
0.40	GO:0005791	rough endoplasmic reticulum
0.40	GO:0030425	dendrite
0.38	GO:0005794	Golgi apparatus

sp|P30987|TA2R_MOUSE
Thromboxane A2 receptor
Search

TBXA2R

0.97	Thromboxane A2 receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.60	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis
0.59	GO:0032496	response to lipopolysaccharide
0.59	GO:0019229	regulation of vasoconstriction
0.59	GO:0045987	positive regulation of smooth muscle contraction
0.57	GO:0019932	second-messenger-mediated signaling
0.55	GO:0006954	inflammatory response
0.49	GO:0045777	positive regulation of blood pressure
0.48	GO:1903524	positive regulation of blood circulation
0.47	GO:0071799	cellular response to prostaglandin D stimulus

0.85	GO:0004954	prostanoid receptor activity
0.35	GO:0005515	protein binding
0.34	GO:0098772	molecular function regulator

0.55	GO:0016607	nuclear speck
0.45	GO:0005886	plasma membrane
0.42	GO:0001669	acrosomal vesicle
0.40	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|P30993|C5AR1_MOUSE
C5a anaphylatoxin chemotactic receptor 1
Search

C5AR1

0.92	G protein-coupled receptor 77

0.84	GO:0038178	complement component C5a signaling pathway
0.67	GO:0006935	chemotaxis
0.66	GO:0050679	positive regulation of epithelial cell proliferation
0.65	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.63	GO:0071622	regulation of granulocyte chemotaxis
0.63	GO:0042789	mRNA transcription by RNA polymerase II
0.63	GO:1902622	regulation of neutrophil migration
0.61	GO:1905523	positive regulation of macrophage migration
0.60	GO:0010758	regulation of macrophage chemotaxis
0.60	GO:0010575	positive regulation of vascular endothelial growth factor production

0.85	GO:0004875	complement receptor activity
0.85	GO:0001847	opsonin receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.43	GO:0001856	complement component C5a binding
0.36	GO:0019956	chemokine binding
0.36	GO:0015026	coreceptor activity
0.34	GO:0004672	protein kinase activity
0.34	GO:0042923	neuropeptide binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0008144	drug binding

0.62	GO:0016323	basolateral plasma membrane
0.61	GO:0045177	apical part of cell
0.45	GO:0005887	integral component of plasma membrane
0.44	GO:0031410	cytoplasmic vesicle
0.44	GO:0045178	basal part of cell
0.38	GO:0009986	cell surface
0.36	GO:0012506	vesicle membrane
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0012505	endomembrane system

sp|P30999|CTND1_MOUSE
Catenin delta-1
Search

CTNND1

0.93	Catenin (Cadherin-associated protein), delta 1

0.75	GO:0098609	cell-cell adhesion
0.53	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.39	GO:0060690	epithelial cell differentiation involved in salivary gland development
0.38	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation
0.38	GO:0072102	glomerulus morphogenesis
0.38	GO:0010954	positive regulation of protein processing
0.37	GO:0007435	salivary gland morphogenesis
0.37	GO:0030216	keratinocyte differentiation
0.37	GO:0001738	morphogenesis of a polarized epithelium
0.36	GO:0007420	brain development

0.79	GO:0045296	cadherin binding
0.48	GO:0005102	receptor binding
0.37	GO:0019899	enzyme binding
0.36	GO:0019904	protein domain specific binding

0.52	GO:0030496	midbody
0.50	GO:0005911	cell-cell junction
0.46	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.41	GO:0005886	plasma membrane
0.38	GO:0030027	lamellipodium
0.38	GO:0005912	adherens junction
0.37	GO:0043197	dendritic spine
0.37	GO:0030426	growth cone
0.37	GO:0070062	extracellular exosome

sp|P31001|DESM_MOUSE
Desmin
Search

DES

0.97	Muscle-specific intermediate filament desmin (Predicted)

0.58	GO:0045109	intermediate filament organization
0.47	GO:0006936	muscle contraction
0.47	GO:0007517	muscle organ development
0.46	GO:0007626	locomotory behavior
0.44	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling
0.43	GO:0045214	sarcomere organization
0.43	GO:0060047	heart contraction
0.42	GO:0014706	striated muscle tissue development
0.36	GO:0045107	intermediate filament polymerization
0.36	GO:0033275	actin-myosin filament sliding

0.62	GO:0005198	structural molecule activity
0.50	GO:0042802	identical protein binding
0.49	GO:0008092	cytoskeletal protein binding
0.34	GO:1990254	keratin filament binding
0.34	GO:0097110	scaffold protein binding
0.34	GO:0008022	protein C-terminus binding
0.33	GO:0019904	protein domain specific binding
0.33	GO:0003725	double-stranded RNA binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding

0.79	GO:0005882	intermediate filament
0.59	GO:0030018	Z disc
0.58	GO:0005916	fascia adherens
0.58	GO:0097512	cardiac myofibril
0.57	GO:0042383	sarcolemma
0.56	GO:0031594	neuromuscular junction
0.45	GO:0005634	nucleus
0.44	GO:0097433	dense body
0.36	GO:0070062	extracellular exosome
0.35	GO:0005921	gap junction

0.33

GO:0004674

sp|P31041|CD28_MOUSE
T-cell-specific surface glycoprotein CD28
Search

CD28

0.97	T-cell-specific surface glycoprotein CD28

0.73	GO:0006955	immune response
0.67	GO:0045086	positive regulation of interleukin-2 biosynthetic process
0.63	GO:0042102	positive regulation of T cell proliferation
0.63	GO:0045840	positive regulation of mitotic nuclear division
0.61	GO:0032753	positive regulation of interleukin-4 production
0.61	GO:0045066	regulatory T cell differentiation
0.61	GO:0032733	positive regulation of interleukin-10 production
0.60	GO:0048304	positive regulation of isotype switching to IgG isotypes
0.60	GO:0002863	positive regulation of inflammatory response to antigenic stimulus
0.60	GO:0045060	negative thymic T cell selection

0.58	GO:0005070	SH3/SH2 adaptor activity
0.57	GO:0002020	protease binding
0.53	GO:0019901	protein kinase binding
0.39	GO:0015026	coreceptor activity
0.37	GO:0042802	identical protein binding
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0046983	protein dimerization activity

0.58	GO:0001772	immunological synapse
0.56	GO:0009897	external side of plasma membrane
0.55	GO:0098636	protein complex involved in cell adhesion
0.40	GO:0044214	spanning component of plasma membrane
0.36	GO:0045121	membrane raft
0.34	GO:0005829	cytosol

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|P31230|AIMP1_MOUSE
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1
Search

AIMP1

0.93	Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

0.55	GO:0001937	negative regulation of endothelial cell proliferation
0.53	GO:0050900	leukocyte migration
0.50	GO:0007267	cell-cell signaling
0.46	GO:0006954	inflammatory response
0.44	GO:0010469	regulation of receptor activity
0.42	GO:0006418	tRNA aminoacylation for protein translation
0.40	GO:0070094	positive regulation of glucagon secretion
0.40	GO:0048514	blood vessel morphogenesis
0.37	GO:0051607	defense response to virus
0.37	GO:0006915	apoptotic process

0.69	GO:0000049	tRNA binding
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0051020	GTPase binding
0.46	GO:0005125	cytokine activity
0.40	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.40	GO:0140101	catalytic activity, acting on a tRNA

0.58	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
0.50	GO:0009986	cell surface
0.48	GO:0017102	methionyl glutamyl tRNA synthetase complex
0.47	GO:0005829	cytosol
0.37	GO:0030133	transport vesicle
0.36	GO:0005615	extracellular space
0.36	GO:0005794	Golgi apparatus
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.40

EC:6.1

GO:0016875

sp|P31240|PDGFB_MOUSE
Platelet-derived growth factor subunit B
Search

PDGFB

0.97	Platelet-derived growth factor subunit B

0.76	GO:0010469	regulation of receptor activity
0.65	GO:0072126	positive regulation of glomerular mesangial cell proliferation
0.65	GO:2000591	positive regulation of metanephric mesenchymal cell migration
0.65	GO:1900238	regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
0.65	GO:1900127	positive regulation of hyaluronan biosynthetic process
0.65	GO:1905176	positive regulation of vascular smooth muscle cell dedifferentiation
0.64	GO:1905064	negative regulation of vascular smooth muscle cell differentiation
0.63	GO:0010512	negative regulation of phosphatidylinositol biosynthetic process
0.63	GO:0010544	negative regulation of platelet activation
0.63	GO:0031954	positive regulation of protein autophosphorylation

0.78	GO:0008083	growth factor activity
0.63	GO:0005161	platelet-derived growth factor receptor binding
0.63	GO:0016176	superoxide-generating NADPH oxidase activator activity
0.62	GO:0048407	platelet-derived growth factor binding
0.61	GO:0042056	chemoattractant activity
0.58	GO:0005518	collagen binding
0.55	GO:0042803	protein homodimerization activity
0.53	GO:0046982	protein heterodimerization activity
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.55	GO:0009986	cell surface
0.45	GO:0005615	extracellular space
0.42	GO:0016323	basolateral plasma membrane
0.38	GO:0005622	intracellular
0.38	GO:0031012	extracellular matrix
0.36	GO:0031983	vesicle lumen
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0012505	endomembrane system

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|P31245|HXA2_MOUSE
Homeobox protein Hox-A2
Search

HOXA2

0.79	Homeobox protein Hox-A2

0.67	GO:0007275	multicellular organism development
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.38	GO:0002076	osteoblast development
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:0071300	cellular response to retinoic acid
0.37	GO:0045668	negative regulation of osteoblast differentiation
0.37	GO:0001709	cell fate determination
0.37	GO:1904888	cranial skeletal system development

0.64	GO:0043565	sequence-specific DNA binding
0.59	GO:0003700	DNA binding transcription factor activity
0.36	GO:0001012	RNA polymerase II regulatory region DNA binding
0.36	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P31254|UBA1Y_MOUSE
Ubiquitin-like modifier-activating enzyme 1 Y
Search

UBA1

0.76	Ubiquitin activating enzyme

0.58	GO:0036211	protein modification process
0.54	GO:0044267	cellular protein metabolic process
0.47	GO:0006974	cellular response to DNA damage stimulus
0.45	GO:0007409	axonogenesis
0.44	GO:0043632	modification-dependent macromolecule catabolic process
0.43	GO:0030163	protein catabolic process
0.40	GO:0006508	proteolysis
0.35	GO:0007283	spermatogenesis

0.74	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0016881	acid-amino acid ligase activity
0.35	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding

0.55	GO:0030057	desmosome
0.53	GO:0030867	rough endoplasmic reticulum membrane
0.53	GO:0000792	heterochromatin
0.53	GO:0005765	lysosomal membrane
0.52	GO:0010008	endosome membrane
0.48	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.44	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:6.3.2

GO:0016881

sp|P31257|HXC10_MOUSE
Homeobox protein Hox-C10
Search

HOXC10

0.96	LOW QUALITY PROTEIN: homeobox protein Hox-C10

0.66	GO:0009954	proximal/distal pattern formation
0.66	GO:0021520	spinal cord motor neuron cell fate specification
0.64	GO:0030326	embryonic limb morphogenesis
0.63	GO:0050905	neuromuscular process
0.63	GO:0009952	anterior/posterior pattern specification
0.62	GO:0001501	skeletal system development
0.58	GO:0006366	transcription by RNA polymerase II
0.58	GO:0045944	positive regulation of transcription by RNA polymerase II
0.48	GO:0007338	single fertilization
0.46	GO:0048935	peripheral nervous system neuron development

0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.60	GO:0001012	RNA polymerase II regulatory region DNA binding
0.56	GO:0003690	double-stranded DNA binding
0.43	GO:0003682	chromatin binding
0.41	GO:0042826	histone deacetylase binding
0.40	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex
0.56	GO:0016604	nuclear body
0.44	GO:0036464	cytoplasmic ribonucleoprotein granule
0.41	GO:0005829	cytosol
0.39	GO:0005667	transcription factor complex

sp|P31266|SUH_MOUSE
Recombining binding protein suppressor of hairless
Search

RBPJ

0.94	Recombination signal binding protein for immunoglobulin kappa J region b

0.73	GO:0072148	epithelial cell fate commitment
0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.70	GO:0060840	artery development
0.70	GO:0001756	somitogenesis
0.69	GO:0035270	endocrine system development
0.68	GO:1905068	positive regulation of canonical Wnt signaling pathway involved in heart development
0.68	GO:1901189	positive regulation of ephrin receptor signaling pathway
0.68	GO:0060485	mesenchyme development
0.67	GO:1901295	regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
0.67	GO:0001525	angiogenesis

0.80	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.80	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.65	GO:0001103	RNA polymerase II repressing transcription factor binding
0.62	GO:0047485	protein N-terminus binding
0.61	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.57	GO:0003682	chromatin binding
0.38	GO:0032403	protein complex binding

0.68	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex
0.61	GO:0005634	nucleus
0.61	GO:0017053	transcriptional repressor complex
0.56	GO:0005667	transcription factor complex
0.52	GO:0070013	intracellular organelle lumen
0.48	GO:0043232	intracellular non-membrane-bounded organelle
0.47	GO:0044446	intracellular organelle part
0.41	GO:0005737	cytoplasm
0.38	GO:0032993	protein-DNA complex

sp|P31310|HXA10_MOUSE
Homeobox protein Hox-A10
Search

HOXA10

0.89	Homeobox protein Hox-A10

0.63	GO:0009954	proximal/distal pattern formation
0.62	GO:0030326	embryonic limb morphogenesis
0.60	GO:0009952	anterior/posterior pattern specification
0.59	GO:0001501	skeletal system development
0.59	GO:0060065	uterus development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0008584	male gonad development
0.56	GO:0006366	transcription by RNA polymerase II
0.56	GO:0010468	regulation of gene expression

0.65	GO:0043565	sequence-specific DNA binding
0.59	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.58	GO:0001012	RNA polymerase II regulatory region DNA binding
0.57	GO:0042826	histone deacetylase binding
0.54	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.52	GO:0005667	transcription factor complex
0.47	GO:0150005	enzyme activator complex
0.47	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.42	GO:0043233	organelle lumen
0.39	GO:0005737	cytoplasm
0.39	GO:0044446	intracellular organelle part

sp|P31311|HXA11_MOUSE
Homeobox protein Hox-A11
Search

HOXA11

0.93	Homeobox protein Hox-A11 (Predicted)

0.61	GO:0007501	mesodermal cell fate specification
0.60	GO:0032332	positive regulation of chondrocyte differentiation
0.60	GO:0060272	embryonic skeletal joint morphogenesis
0.60	GO:0060351	cartilage development involved in endochondral bone morphogenesis
0.59	GO:0060065	uterus development
0.59	GO:0001759	organ induction
0.59	GO:0001658	branching involved in ureteric bud morphogenesis
0.59	GO:0035115	embryonic forelimb morphogenesis
0.59	GO:0009954	proximal/distal pattern formation
0.58	GO:0042733	embryonic digit morphogenesis

0.62	GO:0043565	sequence-specific DNA binding
0.34	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.53	GO:0005667	transcription factor complex
0.51	GO:0032993	protein-DNA complex
0.48	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part

sp|P31313|HXC11_MOUSE
Homeobox protein Hox-C11
Search

HOXC11

0.97	Homeobox protein Hox-3H

0.58	GO:0060272	embryonic skeletal joint morphogenesis
0.57	GO:0001759	organ induction
0.57	GO:0009954	proximal/distal pattern formation
0.56	GO:0042733	embryonic digit morphogenesis
0.56	GO:0001656	metanephros development
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.54	GO:0009952	anterior/posterior pattern specification
0.52	GO:0006366	transcription by RNA polymerase II

0.62	GO:0043565	sequence-specific DNA binding
0.55	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding

0.60	GO:0005634	nucleus
0.48	GO:0005829	cytosol
0.48	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part

sp|P31315|GSX1_MOUSE
GS homeobox 1
Search

GSX1

0.96	Developmental transcription factor

0.64	GO:0021527	spinal cord association neuron differentiation
0.61	GO:0021984	adenohypophysis development
0.61	GO:0048663	neuron fate commitment
0.61	GO:0021854	hypothalamus development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0006366	transcription by RNA polymerase II
0.53	GO:1902680	positive regulation of RNA biosynthetic process
0.43	GO:0021798	forebrain dorsal/ventral pattern formation

0.65	GO:0043565	sequence-specific DNA binding
0.57	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.32	GO:0030529	intracellular ribonucleoprotein complex

sp|P31316|GSX2_MOUSE
GS homeobox 2
Search

GSX2

0.89	Developmental transcription factor

0.67	GO:0021527	spinal cord association neuron differentiation
0.65	GO:0060163	subpallium neuron fate commitment
0.64	GO:0021798	forebrain dorsal/ventral pattern formation
0.63	GO:0021889	olfactory bulb interneuron differentiation
0.63	GO:0048714	positive regulation of oligodendrocyte differentiation
0.63	GO:0002087	regulation of respiratory gaseous exchange by neurological system process
0.63	GO:0021978	telencephalon regionalization
0.63	GO:0048853	forebrain morphogenesis
0.61	GO:0048665	neuron fate specification
0.61	GO:0021575	hindbrain morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.46	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.43	GO:0003690	double-stranded DNA binding
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.35	GO:0005874	microtubule
0.33	GO:0030529	intracellular ribonucleoprotein complex

sp|P31324|KAP3_MOUSE
cAMP-dependent protein kinase type II-beta regulatory subunit
Search

PRKAR2B

0.97	cAMP-dependent protein kinase type II-beta regulatory subunit

0.75	GO:0045859	regulation of protein kinase activity
0.57	GO:0033673	negative regulation of kinase activity
0.55	GO:0007612	learning
0.54	GO:0001933	negative regulation of protein phosphorylation
0.51	GO:0016310	phosphorylation
0.48	GO:0006631	fatty acid metabolic process
0.42	GO:0097338	response to clozapine
0.37	GO:0071377	cellular response to glucagon stimulus
0.37	GO:0003091	renal water homeostasis
0.36	GO:0007596	blood coagulation

0.85	GO:0008603	cAMP-dependent protein kinase regulator activity
0.84	GO:0030552	cAMP binding
0.61	GO:0034236	protein kinase A catalytic subunit binding
0.61	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.56	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0016301	kinase activity
0.46	GO:0019904	protein domain specific binding
0.33	GO:0003735	structural constituent of ribosome

0.83	GO:0005952	cAMP-dependent protein kinase complex
0.56	GO:0097546	ciliary base
0.56	GO:0043198	dendritic shaft
0.55	GO:0005813	centrosome
0.55	GO:0043197	dendritic spine
0.47	GO:0098857	membrane microdomain
0.46	GO:0031588	nucleotide-activated protein kinase complex
0.45	GO:0005930	axoneme
0.44	GO:0005886	plasma membrane
0.39	GO:0043025	neuronal cell body

sp|P31360|PO3F2_MOUSE
POU domain, class 3, transcription factor 2
Search

0.58	POU domain, class 3, transcription factor 2-B

0.75	GO:0007420	brain development
0.67	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.50	GO:0061351	neural precursor cell proliferation
0.50	GO:0030182	neuron differentiation
0.49	GO:0014002	astrocyte development
0.49	GO:0008284	positive regulation of cell proliferation
0.48	GO:0022011	myelination in peripheral nervous system
0.48	GO:0040018	positive regulation of multicellular organism growth
0.48	GO:2001054	negative regulation of mesenchymal cell apoptotic process

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.48	GO:0001105	RNA polymerase II transcription coactivator activity
0.45	GO:0042802	identical protein binding
0.43	GO:0071837	HMG box domain binding
0.32	GO:0016817	hydrolase activity, acting on acid anhydrides
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.61	GO:0005634	nucleus
0.44	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

0.32

EC:3.6

GO:0016817

sp|P31361|PO3F3_MOUSE
POU domain, class 3, transcription factor 3
Search

0.97	POU domain, class 3, transcription factor 3

0.76	GO:0007420	brain development
0.68	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.51	GO:0072227	metanephric macula densa development
0.51	GO:0072069	DCT cell differentiation
0.50	GO:0061351	neural precursor cell proliferation
0.50	GO:0043066	negative regulation of apoptotic process
0.50	GO:0072233	metanephric thick ascending limb development
0.50	GO:0072221	metanephric distal convoluted tubule development
0.50	GO:0072218	metanephric ascending thin limb development

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.49	GO:0071837	HMG box domain binding
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003690	double-stranded DNA binding
0.42	GO:0001105	RNA polymerase II transcription coactivator activity
0.39	GO:0042802	identical protein binding
0.32	GO:0016817	hydrolase activity, acting on acid anhydrides
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding

0.61	GO:0005634	nucleus
0.39	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

0.32

EC:3.6

GO:0016817

sp|P31362|PO2F3_MOUSE
POU domain, class 2, transcription factor 3
Search

POU2F3

0.73	POU domain, class 2, transcription factor 3

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0043922	negative regulation by host of viral transcription
0.57	GO:0006355	regulation of transcription, DNA-templated
0.52	GO:1903508	positive regulation of nucleic acid-templated transcription
0.51	GO:0010628	positive regulation of gene expression
0.46	GO:0002380	immunoglobulin secretion involved in immune response
0.44	GO:0002335	mature B cell differentiation
0.43	GO:0048469	cell maturation
0.38	GO:0008544	epidermis development
0.37	GO:0043588	skin development

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding
0.41	GO:0019904	protein domain specific binding
0.35	GO:0046983	protein dimerization activity

0.61	GO:0005634	nucleus
0.39	GO:0043233	organelle lumen
0.37	GO:0044446	intracellular organelle part
0.36	GO:0005667	transcription factor complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P31387|5HT5B_MOUSE
5-hydroxytryptamine receptor 5B
Search

HTR5A

0.96	5-hydroxytryptamine (Serotonin) receptor 5A, G protein-coupled

0.83	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.55	GO:0019933	cAMP-mediated signaling
0.48	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.40	GO:0032355	response to estradiol
0.40	GO:0021766	hippocampus development

0.83	GO:0099589	serotonin receptor activity
0.80	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.80	GO:0008227	G-protein coupled amine receptor activity
0.51	GO:0051378	serotonin binding
0.34	GO:0008144	drug binding

0.62	GO:0005887	integral component of plasma membrane
0.40	GO:0043204	perikaryon
0.39	GO:0005791	rough endoplasmic reticulum
0.39	GO:0030425	dendrite
0.37	GO:0005794	Golgi apparatus

sp|P31428|DPEP1_MOUSE
Dipeptidase 1
Search

DPEP1

0.57	Dipeptidase

0.60	GO:0006508	proteolysis
0.58	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.56	GO:0030336	negative regulation of cell migration
0.56	GO:0050667	homocysteine metabolic process
0.55	GO:0035690	cellular response to drug
0.54	GO:0006915	apoptotic process
0.53	GO:0016999	antibiotic metabolic process
0.44	GO:0071731	response to nitric oxide
0.44	GO:1902170	cellular response to reactive nitrogen species
0.44	GO:0071277	cellular response to calcium ion

0.77	GO:0016805	dipeptidase activity
0.74	GO:0008239	dipeptidyl-peptidase activity
0.70	GO:0008235	metalloexopeptidase activity
0.59	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.54	GO:0046872	metal ion binding
0.52	GO:0072341	modified amino acid binding
0.45	GO:0034235	GPI anchor binding
0.33	GO:0005515	protein binding

0.77	GO:0031225	anchored component of membrane
0.55	GO:0045177	apical part of cell
0.50	GO:0030054	cell junction
0.44	GO:0005634	nucleus
0.44	GO:0005886	plasma membrane
0.42	GO:0005902	microvillus
0.40	GO:0005615	extracellular space
0.40	GO:0120038	plasma membrane bounded cell projection part
0.37	GO:1903561	extracellular vesicle
0.34	GO:0005789	endoplasmic reticulum membrane

0.77

EC:3.4.13

GO:0016805

sp|P31482|PA2GA_MOUSE
Phospholipase A2, membrane associated
Search

PLA2G2A

0.64	Group IID secretory phospholipase A2

0.82	GO:0050482	arachidonic acid secretion
0.72	GO:0016042	lipid catabolic process
0.67	GO:0006644	phospholipid metabolic process
0.47	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.44	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
0.44	GO:0009405	pathogenesis
0.43	GO:0046486	glycerolipid metabolic process
0.43	GO:0042130	negative regulation of T cell proliferation
0.37	GO:0042742	defense response to bacterium
0.37	GO:0034374	low-density lipoprotein particle remodeling

0.82	GO:0004623	phospholipase A2 activity
0.78	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.78	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.70	GO:0005509	calcium ion binding
0.46	GO:0090729	toxin activity
0.44	GO:0005543	phospholipid binding
0.43	GO:0043395	heparan sulfate proteoglycan binding
0.42	GO:0008201	heparin binding

0.66	GO:0005576	extracellular region
0.43	GO:0005783	endoplasmic reticulum
0.38	GO:0072556	other organism presynaptic membrane
0.37	GO:0030141	secretory granule
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0035792	other organism postsynaptic membrane
0.35	GO:0005886	plasma membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.82

EC:3.1.1.4

GO:0004623

sp|P31532|SAA4_MOUSE
Serum amyloid A-4 protein
Search

0.94	Serum amyloid A protein (Fragment)

0.85	GO:0006953	acute-phase response
0.56	GO:0050918	positive chemotaxis
0.54	GO:0060326	cell chemotaxis
0.41	GO:0007596	blood coagulation
0.40	GO:0010739	positive regulation of protein kinase A signaling
0.40	GO:0043473	pigmentation
0.40	GO:0050996	positive regulation of lipid catabolic process
0.40	GO:0043410	positive regulation of MAPK cascade
0.39	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.39	GO:0070372	regulation of ERK1 and ERK2 cascade

0.57	GO:0042056	chemoattractant activity
0.40	GO:0008201	heparin binding
0.36	GO:0035662	Toll-like receptor 4 binding
0.35	GO:0001664	G-protein coupled receptor binding

0.85	GO:0034364	high-density lipoprotein particle
0.42	GO:0070062	extracellular exosome
0.42	GO:0031084	BLOC-2 complex
0.37	GO:0071682	endocytic vesicle lumen
0.36	GO:0005881	cytoplasmic microtubule
0.30	GO:0016020	membrane

sp|P31648|SC6A1_MOUSE
Sodium- and chloride-dependent GABA transporter 1
Search

SLC6A1

0.58	Sodium- and chloride-dependent GABA transporter 1

0.85	GO:0015812	gamma-aminobutyric acid transport
0.66	GO:0032229	negative regulation of synaptic transmission, GABAergic
0.66	GO:0014054	positive regulation of gamma-aminobutyric acid secretion
0.65	GO:0010288	response to lead ion
0.63	GO:0042220	response to cocaine
0.62	GO:0009744	response to sucrose
0.62	GO:0032355	response to estradiol
0.61	GO:0043090	amino acid import
0.61	GO:0051592	response to calcium ion
0.60	GO:0007612	learning

0.86	GO:0005332	gamma-aminobutyric acid:sodium symporter activity
0.43	GO:0046872	metal ion binding
0.41	GO:0005515	protein binding

0.67	GO:0005887	integral component of plasma membrane
0.65	GO:0030424	axon
0.55	GO:0009986	cell surface

sp|P31649|S6A13_MOUSE
Sodium- and chloride-dependent GABA transporter 2
Search

SLC6A13

0.56	Solute carrier family 6 member 13

0.76	GO:0006836	neurotransmitter transport
0.58	GO:0015718	monocarboxylic acid transport
0.55	GO:0006865	amino acid transport
0.55	GO:0055085	transmembrane transport

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.65	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity
0.64	GO:0015355	secondary active monocarboxylate transmembrane transporter activity
0.60	GO:0005283	sodium:amino acid symporter activity
0.59	GO:0015296	anion:cation symporter activity

0.55

GO:0005887

integral component of plasma membrane

sp|P31650|S6A11_MOUSE
Sodium- and chloride-dependent GABA transporter 3
Search

SLC6A11

0.43	Sodium- and chloride-dependent GABA transporter 3

0.76	GO:0006836	neurotransmitter transport
0.60	GO:0015718	monocarboxylic acid transport
0.57	GO:0006865	amino acid transport
0.55	GO:0055085	transmembrane transport
0.37	GO:0007420	brain development
0.36	GO:0042493	response to drug
0.32	GO:0006812	cation transport

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.68	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity
0.67	GO:0015355	secondary active monocarboxylate transmembrane transporter activity
0.62	GO:0005283	sodium:amino acid symporter activity
0.62	GO:0015296	anion:cation symporter activity
0.38	GO:0042165	neurotransmitter binding
0.34	GO:0015193	L-proline transmembrane transporter activity

0.56	GO:0005887	integral component of plasma membrane
0.36	GO:0042995	cell projection
0.33	GO:0005737	cytoplasm

sp|P31651|S6A12_MOUSE
Sodium- and chloride-dependent betaine transporter
Search

SLC6A12

0.49	Sodium- and chloride-dependent betaine transporter

0.74	GO:0015812	gamma-aminobutyric acid transport
0.54	GO:0055085	transmembrane transport
0.36	GO:0009992	cellular water homeostasis
0.35	GO:0071474	cellular hyperosmotic response
0.34	GO:0010033	response to organic substance
0.34	GO:0032259	methylation

0.78	GO:0005332	gamma-aminobutyric acid:sodium symporter activity
0.34	GO:0008168	methyltransferase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.33	GO:0003677	DNA binding

0.60	GO:0005887	integral component of plasma membrane
0.33	GO:0005634	nucleus

0.34

GO:0008168

sp|P31695|NOTC4_MOUSE
Neurogenic locus notch homolog protein 4
Search

0.81	GO:0007219	Notch signaling pathway
0.71	GO:0030154	cell differentiation
0.68	GO:0007275	multicellular organism development
0.66	GO:0050793	regulation of developmental process
0.51	GO:2001141	regulation of RNA biosynthetic process
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.51	GO:0010468	regulation of gene expression
0.45	GO:0097150	neuronal stem cell population maintenance
0.45	GO:0009888	tissue development
0.45	GO:0048646	anatomical structure formation involved in morphogenesis

0.69	GO:0005509	calcium ion binding
0.57	GO:0004872	receptor activity
0.40	GO:0005112	Notch binding
0.38	GO:0003682	chromatin binding
0.37	GO:0030234	enzyme regulator activity
0.37	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.36	GO:0001047	core promoter binding
0.36	GO:0046982	protein heterodimerization activity
0.36	GO:0043565	sequence-specific DNA binding
0.35	GO:0003700	DNA binding transcription factor activity

0.50	GO:0009986	cell surface
0.39	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex
0.39	GO:0031410	cytoplasmic vesicle
0.38	GO:0012505	endomembrane system
0.38	GO:0005912	adherens junction
0.38	GO:0005634	nucleus
0.37	GO:0035003	subapical complex
0.37	GO:0043235	receptor complex
0.36	GO:0016324	apical plasma membrane
0.36	GO:0005764	lysosome

sp|P31725|S10A9_MOUSE
Protein S100-A9
Search

0.44	EF-HAND 2 containing protein

0.88	GO:0035606	peptidyl-cysteine S-trans-nitrosylation
0.88	GO:0070488	neutrophil aggregation
0.87	GO:0045113	regulation of integrin biosynthetic process
0.86	GO:0002523	leukocyte migration involved in inflammatory response
0.86	GO:0014002	astrocyte development
0.86	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.85	GO:0030194	positive regulation of blood coagulation
0.85	GO:0030593	neutrophil chemotaxis
0.85	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.85	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process

0.87	GO:0035662	Toll-like receptor 4 binding
0.87	GO:0050544	arachidonic acid binding
0.86	GO:0050786	RAGE receptor binding
0.74	GO:0008017	microtubule binding
0.70	GO:0005509	calcium ion binding
0.63	GO:0008270	zinc ion binding

0.75	GO:0030054	cell junction
0.73	GO:0005615	extracellular space
0.70	GO:0005654	nucleoplasm
0.68	GO:0005829	cytosol

sp|P31750|AKT1_MOUSE
RAC-alpha serine/threonine-protein kinase
Search

AKT1

0.42	RAC-alpha serine/threonine-protein kinase

0.63	GO:0006468	protein phosphorylation
0.62	GO:1990418	response to insulin-like growth factor stimulus
0.59	GO:0060416	response to growth hormone
0.55	GO:1903721	positive regulation of I-kappaB phosphorylation
0.55	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.55	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport
0.55	GO:0006924	activation-induced cell death of T cells
0.55	GO:0031999	negative regulation of fatty acid beta-oxidation
0.55	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.55	GO:0035655	interleukin-18-mediated signaling pathway

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030235	nitric-oxide synthase regulator activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0071889	14-3-3 protein binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.54	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.53	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.51	GO:0004712	protein serine/threonine/tyrosine kinase activity

0.52	GO:0036064	ciliary basal body
0.49	GO:0005819	spindle
0.49	GO:0005911	cell-cell junction
0.47	GO:0031982	vesicle
0.46	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.43	GO:0005739	mitochondrion
0.42	GO:0043234	protein complex
0.41	GO:0005886	plasma membrane
0.35	GO:0019028	viral capsid

0.70

GO:0004674

sp|P31786|ACBP_MOUSE
Acyl-CoA-binding protein
Search

DBI

0.61	Benzodiazepine receptor ligand

0.47	GO:0036151	phosphatidylcholine acyl-chain remodeling
0.38	GO:0021670	lateral ventricle development
0.37	GO:0001662	behavioral fear response
0.37	GO:0032228	regulation of synaptic transmission, GABAergic
0.37	GO:0060291	long-term synaptic potentiation
0.37	GO:0001942	hair follicle development
0.37	GO:0007611	learning or memory
0.36	GO:0006641	triglyceride metabolic process
0.36	GO:0001300	chronological cell aging
0.36	GO:0042761	very long-chain fatty acid biosynthetic process

0.82	GO:0000062	fatty-acyl-CoA binding
0.41	GO:0046983	protein dimerization activity
0.40	GO:0008289	lipid binding
0.35	GO:0030156	benzodiazepine receptor binding
0.33	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0008483	transaminase activity
0.33	GO:0030170	pyridoxal phosphate binding
0.32	GO:0016853	isomerase activity

0.40	GO:0005794	Golgi apparatus
0.39	GO:0005783	endoplasmic reticulum
0.37	GO:0008021	synaptic vesicle
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005576	extracellular region
0.35	GO:0043292	contractile fiber
0.34	GO:0005739	mitochondrion
0.34	GO:0044446	intracellular organelle part
0.34	GO:0043209	myelin sheath
0.33	GO:0005886	plasma membrane

0.33

GO:0016746

sp|P31809|CEAM1_MOUSE
Carcinoembryonic antigen-related cell adhesion molecule 1
Search

0.82	Pregnancy-specific beta-1-glycoprotein 8

0.52	GO:0043317	regulation of cytotoxic T cell degranulation
0.51	GO:0002859	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.50	GO:0001915	negative regulation of T cell mediated cytotoxicity
0.49	GO:0043301	negative regulation of leukocyte degranulation
0.49	GO:0050860	negative regulation of T cell receptor signaling pathway
0.48	GO:0044319	wound healing, spreading of cells
0.47	GO:0050868	negative regulation of T cell activation
0.47	GO:2000346	negative regulation of hepatocyte proliferation
0.47	GO:0038016	insulin receptor internalization
0.47	GO:1903385	regulation of homophilic cell adhesion

0.51	GO:0031005	filamin binding
0.49	GO:1990782	protein tyrosine kinase binding
0.49	GO:0019903	protein phosphatase binding
0.46	GO:0042803	protein homodimerization activity
0.45	GO:0015125	bile acid transmembrane transporter activity
0.45	GO:0003779	actin binding
0.45	GO:0005130	granulocyte colony-stimulating factor receptor binding
0.44	GO:0046790	virion binding
0.44	GO:0035325	Toll-like receptor binding
0.44	GO:0001618	virus receptor activity

0.50	GO:0042101	T cell receptor complex
0.47	GO:0009986	cell surface
0.46	GO:0005911	cell-cell junction
0.46	GO:0031528	microvillus membrane
0.45	GO:0009925	basal plasma membrane
0.44	GO:0016328	lateral plasma membrane
0.44	GO:0005615	extracellular space
0.43	GO:0016324	apical plasma membrane
0.43	GO:0098552	side of membrane
0.43	GO:0005912	adherens junction

0.32

EC:3.4.23

GO:0004190

sp|P31938|MP2K1_MOUSE
Dual specificity mitogen-activated protein kinase kinase 1
Search

MAP2K1

0.88	Dual specificity mitogen-activated protein kinase kinase 1

0.62	GO:0006468	protein phosphorylation
0.60	GO:0060502	epithelial cell proliferation involved in lung morphogenesis
0.59	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA
0.59	GO:0060440	trachea formation
0.58	GO:0090398	cellular senescence
0.57	GO:0030878	thyroid gland development
0.57	GO:0060020	Bergmann glial cell differentiation
0.57	GO:0048679	regulation of axon regeneration
0.56	GO:0048538	thymus development
0.56	GO:0060324	face development

0.68	GO:0004674	protein serine/threonine kinase activity
0.59	GO:0004728	signal transducer, downstream of receptor, with protein tyrosine phosphatase activity
0.58	GO:0004708	MAP kinase kinase activity
0.57	GO:0097110	scaffold protein binding
0.56	GO:0047485	protein N-terminus binding
0.56	GO:0043539	protein serine/threonine kinase activator activity
0.55	GO:0008022	protein C-terminus binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding

0.49	GO:0005783	endoplasmic reticulum
0.49	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.42	GO:0005815	microtubule organizing center
0.38	GO:0005925	focal adhesion
0.38	GO:0005770	late endosome
0.38	GO:0005769	early endosome
0.38	GO:0005634	nucleus
0.37	GO:0070062	extracellular exosome
0.37	GO:0005794	Golgi apparatus

0.68

GO:0004674

sp|P31955|AREG_MOUSE
Amphiregulin
Search

AREG

0.97	Amphiregulin short form

0.69	GO:0060598	dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis
0.67	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation
0.67	GO:0060744	mammary gland branching involved in thelarche
0.66	GO:0007173	epidermal growth factor receptor signaling pathway
0.65	GO:0060749	mammary gland alveolus development
0.65	GO:0032355	response to estradiol
0.65	GO:0045740	positive regulation of DNA replication
0.63	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.61	GO:0008284	positive regulation of cell proliferation
0.55	GO:0007186	G-protein coupled receptor signaling pathway

0.54	GO:0005154	epidermal growth factor receptor binding
0.50	GO:0008083	growth factor activity
0.42	GO:0005125	cytokine activity

0.58	GO:0009986	cell surface
0.57	GO:0005615	extracellular space
0.49	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm
0.36	GO:0012506	vesicle membrane
0.36	GO:0097708	intracellular vesicle
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0031984	organelle subcompartment

sp|P31996|CD68_MOUSE
Macrosialin
Search

CD68

0.97	macrosialin

0.57	GO:0071310	cellular response to organic substance
0.38	GO:0043312	neutrophil degranulation
0.33	GO:0006413	translational initiation
0.33	GO:0023014	signal transduction by protein phosphorylation
0.32	GO:0000160	phosphorelay signal transduction system
0.32	GO:0005975	carbohydrate metabolic process

0.34	GO:0004004	ATP-dependent RNA helicase activity
0.33	GO:0003743	translation initiation factor activity
0.33	GO:0000155	phosphorelay sensor kinase activity
0.32	GO:0008061	chitin binding
0.32	GO:0005509	calcium ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.82	GO:0005765	lysosomal membrane
0.38	GO:0005766	primary lysosome
0.38	GO:0030667	secretory granule membrane
0.37	GO:0010008	endosome membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.7.3

GO:0000155

sp|P32020|NLTP_MOUSE
Non-specific lipid-transfer protein
Search

SCP2

0.60	Sterol carrier protein 2

0.60	GO:1901373	lipid hydroperoxide transport
0.59	GO:0032379	positive regulation of intracellular lipid transport
0.58	GO:0032380	regulation of intracellular sterol transport
0.57	GO:0032376	positive regulation of cholesterol transport
0.52	GO:0007031	peroxisome organization
0.45	GO:0015918	sterol transport
0.43	GO:0015914	phospholipid transport
0.43	GO:0006694	steroid biosynthetic process
0.40	GO:0032959	inositol trisphosphate biosynthetic process
0.39	GO:0042448	progesterone metabolic process

0.64	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.59	GO:0070538	oleic acid binding
0.58	GO:0036042	long-chain fatty acyl-CoA binding
0.55	GO:0032934	sterol binding
0.54	GO:0043178	alcohol binding
0.49	GO:0005102	receptor binding
0.45	GO:0015248	sterol transporter activity
0.39	GO:0008526	phosphatidylinositol transporter activity
0.37	GO:0005518	collagen binding
0.36	GO:1904121	phosphatidylethanolamine transporter activity

0.52	GO:0005777	peroxisome
0.48	GO:0005654	nucleoplasm
0.44	GO:0005739	mitochondrion
0.43	GO:0043234	protein complex
0.38	GO:0005615	extracellular space
0.37	GO:0031907	microbody lumen
0.36	GO:1903561	extracellular vesicle
0.36	GO:0031012	extracellular matrix
0.35	GO:0031312	extrinsic component of organelle membrane
0.34	GO:0031968	organelle outer membrane

0.64

GO:0016747

sp|P32037|GTR3_MOUSE
Solute carrier family 2, facilitated glucose transporter member 3
Search

SLC2A3

0.76	Glucose transporter

0.73	GO:1904659	glucose transmembrane transport
0.54	GO:0070837	dehydroascorbic acid transport
0.40	GO:0071548	response to dexamethasone
0.40	GO:0032868	response to insulin
0.37	GO:1904016	response to Thyroglobulin triiodothyronine
0.37	GO:0042149	cellular response to glucose starvation
0.37	GO:0007275	multicellular organism development
0.36	GO:0046323	glucose import
0.36	GO:0006461	protein complex assembly
0.36	GO:0019852	L-ascorbic acid metabolic process

0.74	GO:0005355	glucose transmembrane transporter activity
0.54	GO:0033300	dehydroascorbic acid transmembrane transporter activity
0.44	GO:0005536	glucose binding
0.39	GO:0043621	protein self-association
0.37	GO:0042802	identical protein binding
0.36	GO:0033222	xylose binding
0.36	GO:0016936	galactoside binding
0.36	GO:0019900	kinase binding
0.34	GO:0042910	xenobiotic transmembrane transporter activity

0.51	GO:0002080	acrosomal membrane
0.42	GO:0005886	plasma membrane
0.38	GO:0030496	midbody
0.38	GO:0030864	cortical actin cytoskeleton
0.38	GO:0045121	membrane raft
0.38	GO:0001939	female pronucleus
0.38	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:0045177	apical part of cell
0.35	GO:0101003	ficolin-1-rich granule membrane

sp|P32043|HXC5_MOUSE
Homeobox protein Hox-C5
Search

HOXC5

0.72	homeobox protein Hox-C5

0.65	GO:0007275	multicellular organism development
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.36	GO:0006351	transcription, DNA-templated

0.61	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity

0.59	GO:0005634	nucleus
0.42	GO:0030054	cell junction
0.40	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part

sp|P32067|LA_MOUSE
Lupus La protein homolog
Search

SSB

0.91	Sjogren syndrome antigen B

0.76	GO:0071045	nuclear histone mRNA catabolic process
0.73	GO:1903608	protein localization to cytoplasmic stress granule
0.73	GO:0075522	IRES-dependent viral translational initiation
0.71	GO:0071431	tRNA-containing ribonucleoprotein complex export from nucleus
0.70	GO:0051031	tRNA transport
0.69	GO:0097064	ncRNA export from nucleus
0.64	GO:0001682	tRNA 5'-leader removal
0.64	GO:0042780	tRNA 3'-end processing

0.73	GO:1990825	sequence-specific mRNA binding
0.70	GO:0008266	poly(U) RNA binding
0.57	GO:0000049	tRNA binding

0.61	GO:0005634	nucleus
0.61	GO:0030529	intracellular ribonucleoprotein complex
0.43	GO:0005737	cytoplasm

sp|P32082|GHRHR_MOUSE
Growth hormone-releasing hormone receptor
Search

GHRHR

0.97	Pituitary growth hormone-releasing hormone receptor

0.67	GO:0007166	cell surface receptor signaling pathway
0.67	GO:0007186	G-protein coupled receptor signaling pathway
0.59	GO:0060133	somatotropin secreting cell development
0.58	GO:0030252	growth hormone secretion
0.58	GO:0060124	positive regulation of growth hormone secretion
0.57	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.56	GO:0040018	positive regulation of multicellular organism growth
0.55	GO:0030104	water homeostasis
0.55	GO:0043627	response to estrogen
0.55	GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway

0.68	GO:0004930	G-protein coupled receptor activity
0.56	GO:0017046	peptide hormone binding
0.54	GO:0019838	growth factor binding

0.56	GO:0005640	nuclear outer membrane
0.55	GO:0016363	nuclear matrix
0.54	GO:0005637	nuclear inner membrane
0.53	GO:0030141	secretory granule
0.51	GO:0009986	cell surface
0.49	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P32114|PAX2_MOUSE
Paired box protein Pax-2
Search

PAX2

0.93	Paired box protein Pax-2

0.69	GO:0007275	multicellular organism development
0.61	GO:0045918	negative regulation of cytolysis
0.58	GO:2000378	negative regulation of reactive oxygen species metabolic process
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0061138	morphogenesis of a branching epithelium
0.56	GO:0010468	regulation of gene expression
0.56	GO:0050679	positive regulation of epithelial cell proliferation

0.54	GO:0003677	DNA binding
0.52	GO:0001067	regulatory region nucleic acid binding
0.50	GO:0008134	transcription factor binding
0.42	GO:0016175	superoxide-generating NADPH oxidase activity
0.40	GO:0070742	C2H2 zinc finger domain binding
0.38	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.58	GO:0034451	centriolar satellite
0.50	GO:0005794	Golgi apparatus
0.48	GO:0070013	intracellular organelle lumen
0.39	GO:0032993	protein-DNA complex
0.39	GO:0005764	lysosome
0.36	GO:0043234	protein complex

0.42

EC:1.6.3

GO:0016175

sp|P32115|PAX4_MOUSE
Paired box protein Pax-4
Search

PAX4

0.89	Paired box protein Pax-4

0.71	GO:0031016	pancreas development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0045597	positive regulation of cell differentiation
0.52	GO:0051253	negative regulation of RNA metabolic process
0.52	GO:0010558	negative regulation of macromolecule biosynthetic process
0.52	GO:0031327	negative regulation of cellular biosynthetic process
0.48	GO:0060041	retina development in camera-type eye

0.63	GO:0043565	sequence-specific DNA binding
0.58	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding
0.56	GO:0035326	enhancer binding
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0003690	double-stranded DNA binding
0.46	GO:0070410	co-SMAD binding
0.46	GO:0071837	HMG box domain binding
0.46	GO:0070412	R-SMAD binding
0.46	GO:0035035	histone acetyltransferase binding
0.44	GO:0001047	core promoter binding

0.61	GO:0005634	nucleus
0.42	GO:0070013	intracellular organelle lumen
0.41	GO:0000785	chromatin
0.40	GO:0005829	cytosol
0.36	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

0.35

GO:0004842

sp|P32211|ACM4_MOUSE
Muscarinic acetylcholine receptor M4
Search

CHRM4

0.81	Muscarinic acetylcholine receptor

0.84	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.70	GO:0040012	regulation of locomotion
0.60	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.58	GO:0008016	regulation of heart contraction
0.51	GO:0007271	synaptic transmission, cholinergic
0.50	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.44	GO:0009615	response to virus
0.44	GO:0006940	regulation of smooth muscle contraction
0.37	GO:1903523	negative regulation of blood circulation
0.35	GO:0007194	negative regulation of adenylate cyclase activity

0.85	GO:0016907	G-protein coupled acetylcholine receptor activity
0.49	GO:1990763	arrestin family protein binding
0.34	GO:0005085	guanyl-nucleotide exchange factor activity
0.33	GO:0008144	drug binding

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.66	GO:0005887	integral component of plasma membrane
0.39	GO:0032280	symmetric synapse
0.39	GO:0043679	axon terminus
0.39	GO:0032279	asymmetric synapse
0.38	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.35	GO:0042383	sarcolemma
0.35	GO:0099572	postsynaptic specialization

sp|P32233|DRG1_MOUSE
Developmentally-regulated GTP-binding protein 1
Search

DRG1

0.89	Developmentally-regulated GTP-binding protein 1

0.33	GO:0007275	multicellular organism development
0.33	GO:0006351	transcription, DNA-templated

0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0042802	identical protein binding
0.34	GO:0008134	transcription factor binding

0.52	GO:0005844	polysome
0.50	GO:0016604	nuclear body
0.46	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P32240|PE2R4_MOUSE
Prostaglandin E2 receptor EP4 subtype
Search

PTGER4

0.88	Prostaglandin E receptor 4

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.67	GO:2000419	regulation of eosinophil extravasation
0.67	GO:2000417	negative regulation of eosinophil migration
0.66	GO:0033624	negative regulation of integrin activation
0.65	GO:0002692	negative regulation of cellular extravasation
0.61	GO:0050728	negative regulation of inflammatory response
0.61	GO:0042093	T-helper cell differentiation
0.60	GO:0050710	negative regulation of cytokine secretion
0.60	GO:0071260	cellular response to mechanical stimulus
0.59	GO:0050715	positive regulation of cytokine secretion

0.85	GO:0004957	prostaglandin E receptor activity
0.34	GO:0005515	protein binding

0.37	GO:0005886	plasma membrane
0.36	GO:0044306	neuron projection terminus
0.36	GO:0043025	neuronal cell body
0.36	GO:0031965	nuclear membrane
0.30	GO:0016021	integral component of membrane

sp|P32261|ANT3_MOUSE
Antithrombin-III
Search

SERPINC1

0.97	Serpin peptidase inhibitor clade C member 1

0.85	GO:2000266	regulation of blood coagulation, intrinsic pathway
0.73	GO:0010951	negative regulation of endopeptidase activity
0.45	GO:0071391	cellular response to estrogen stimulus
0.44	GO:0002438	acute inflammatory response to antigenic stimulus
0.44	GO:0007595	lactation
0.42	GO:0007584	response to nutrient
0.41	GO:0007596	blood coagulation
0.39	GO:0042129	regulation of T cell proliferation
0.37	GO:0010608	posttranscriptional regulation of gene expression
0.37	GO:0046628	positive regulation of insulin receptor signaling pathway

0.78	GO:0008201	heparin binding
0.76	GO:0004867	serine-type endopeptidase inhibitor activity
0.58	GO:0002020	protease binding
0.53	GO:0042802	identical protein binding
0.39	GO:0003730	mRNA 3'-UTR binding
0.34	GO:0046872	metal ion binding
0.34	GO:0035613	RNA stem-loop binding
0.33	GO:0016874	ligase activity
0.32	GO:0008233	peptidase activity

0.73	GO:0005615	extracellular space
0.41	GO:0060205	cytoplasmic vesicle lumen
0.39	GO:0043025	neuronal cell body
0.39	GO:0030141	secretory granule
0.39	GO:1903561	extracellular vesicle
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0005886	plasma membrane
0.33	GO:0000932	P-body
0.33	GO:0010494	cytoplasmic stress granule

0.33

GO:0016874

sp|P32299|BKRB2_MOUSE
B2 bradykinin receptor
Search

BDKRB2

0.97	Bradykinin receptor, beta 2

0.82	GO:0006939	smooth muscle contraction
0.82	GO:0042310	vasoconstriction
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.63	GO:1902238	regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
0.62	GO:0006950	response to stress
0.62	GO:1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
0.60	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
0.60	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.59	GO:0042311	vasodilation
0.57	GO:0050482	arachidonic acid secretion

0.86	GO:0004947	bradykinin receptor activity
0.63	GO:0031702	type 1 angiotensin receptor binding
0.59	GO:0002020	protease binding
0.53	GO:0046982	protein heterodimerization activity
0.37	GO:0031698	beta-2 adrenergic receptor binding
0.35	GO:0004435	phosphatidylinositol phospholipase C activity
0.35	GO:0070915	lysophosphatidic acid receptor activity
0.33	GO:0019957	C-C chemokine binding
0.33	GO:0016493	C-C chemokine receptor activity
0.33	GO:0001594	trace-amine receptor activity

0.54	GO:0005768	endosome
0.44	GO:0005886	plasma membrane
0.33	GO:0005884	actin filament
0.33	GO:0031965	nuclear membrane
0.32	GO:0005654	nucleoplasm
0.32	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.35	EC:3.1.4.11	GO:0004435
0.35	KEGG:R03435	GO:0004435

sp|P32300|OPRD_MOUSE
Delta-type opioid receptor
Search

OPRD1

0.97	Delta-type opioid receptor

0.86	GO:0038003	opioid receptor signaling pathway
0.62	GO:0007218	neuropeptide signaling pathway
0.58	GO:0032460	negative regulation of protein oligomerization
0.58	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.57	GO:0000060	protein import into nucleus, translocation
0.56	GO:0030534	adult behavior
0.56	GO:0051881	regulation of mitochondrial membrane potential
0.56	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.55	GO:0071456	cellular response to hypoxia
0.55	GO:0007626	locomotory behavior

0.86	GO:0004985	opioid receptor activity
0.52	GO:0042923	neuropeptide binding
0.52	GO:0004977	melanocortin receptor activity
0.51	GO:0008188	neuropeptide receptor activity
0.51	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.44	GO:0001965	G-protein alpha-subunit binding
0.41	GO:0031681	G-protein beta-subunit binding
0.37	GO:0005245	voltage-gated calcium channel activity
0.36	GO:0031005	filamin binding
0.36	GO:0008022	protein C-terminus binding

0.49	GO:0031226	intrinsic component of plasma membrane
0.48	GO:0043005	neuron projection
0.42	GO:0045203	integral component of cell outer membrane
0.41	GO:0036477	somatodendritic compartment
0.41	GO:0031256	leading edge membrane
0.41	GO:0031253	cell projection membrane
0.40	GO:0098857	membrane microdomain
0.40	GO:0098794	postsynapse
0.40	GO:0031982	vesicle
0.39	GO:0097060	synaptic membrane

sp|P32304|5HT7R_MOUSE
5-hydroxytryptamine receptor 7
Search

HTR7

0.91	Serotonin 5-hydroxytryptamine 7-a receptor

0.84	GO:0006939	smooth muscle contraction
0.83	GO:0042310	vasoconstriction
0.83	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.80	GO:0007623	circadian rhythm
0.76	GO:0007268	chemical synaptic transmission
0.46	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.37	GO:0007192	adenylate cyclase-activating serotonin receptor signaling pathway
0.36	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep
0.36	GO:0014063	negative regulation of serotonin secretion
0.36	GO:0051412	response to corticosterone

0.84	GO:0099589	serotonin receptor activity
0.80	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.80	GO:0008227	G-protein coupled amine receptor activity
0.47	GO:0051378	serotonin binding

0.49	GO:0005887	integral component of plasma membrane
0.35	GO:0043679	axon terminus
0.35	GO:0005791	rough endoplasmic reticulum
0.35	GO:0008021	synaptic vesicle
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite

sp|P32442|MEOX1_MOUSE
Homeobox protein MOX-1
Search

MEOX1

0.94	Homeobox protein MOX-1

0.69	GO:0001757	somite specification
0.64	GO:0061056	sclerotome development
0.60	GO:0006366	transcription by RNA polymerase II
0.60	GO:0045944	positive regulation of transcription by RNA polymerase II
0.51	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis
0.50	GO:0070997	neuron death
0.50	GO:0061061	muscle structure development
0.49	GO:0060021	palate development
0.49	GO:0060173	limb development
0.48	GO:0014706	striated muscle tissue development

0.64	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0071837	HMG box domain binding
0.60	GO:0001012	RNA polymerase II regulatory region DNA binding
0.59	GO:0001047	core promoter binding
0.57	GO:0003690	double-stranded DNA binding
0.56	GO:0003682	chromatin binding
0.51	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.49	GO:0035326	enhancer binding

0.60	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part

sp|P32443|MEOX2_MOUSE
Homeobox protein MOX-2
Search

MEOX2

0.97	Homeobox protein MOX-2

0.67	GO:0001757	somite specification
0.64	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis
0.62	GO:0070997	neuron death
0.61	GO:0060021	palate development
0.60	GO:0007519	skeletal muscle tissue development
0.60	GO:0060173	limb development
0.58	GO:0001525	angiogenesis
0.58	GO:0006366	transcription by RNA polymerase II
0.58	GO:0045944	positive regulation of transcription by RNA polymerase II
0.46	GO:0061056	sclerotome development

0.63	GO:0043565	sequence-specific DNA binding
0.63	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.62	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.61	GO:0035326	enhancer binding
0.59	GO:0001012	RNA polymerase II regulatory region DNA binding
0.56	GO:0003690	double-stranded DNA binding
0.45	GO:0071837	HMG box domain binding
0.43	GO:0001047	core promoter binding
0.43	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part

sp|P32507|NECT2_MOUSE
Nectin-2
Search

0.97	Poliovirus receptor

0.71	GO:0007286	spermatid development
0.64	GO:0007155	cell adhesion
0.64	GO:0060370	susceptibility to T cell mediated cytotoxicity
0.63	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity
0.62	GO:0002857	positive regulation of natural killer cell mediated immune response to tumor cell
0.62	GO:0002858	regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.61	GO:0046814	coreceptor-mediated virion attachment to host cell
0.60	GO:0030382	sperm mitochondrion organization
0.59	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.59	GO:0044409	entry into host

0.71	GO:0050839	cell adhesion molecule binding
0.66	GO:0042803	protein homodimerization activity
0.64	GO:0046982	protein heterodimerization activity
0.47	GO:0005102	receptor binding
0.44	GO:0004872	receptor activity
0.39	GO:0104005	hijacked molecular function
0.35	GO:0045503	dynein light chain binding
0.34	GO:0004871	signal transducer activity
0.33	GO:0008320	protein transmembrane transporter activity

0.67	GO:0005911	cell-cell junction
0.58	GO:0005912	adherens junction
0.52	GO:0009986	cell surface
0.45	GO:0005887	integral component of plasma membrane
0.41	GO:0030055	cell-substrate junction
0.41	GO:0070062	extracellular exosome
0.34	GO:0005741	mitochondrial outer membrane

sp|P32648|VIP_MOUSE
VIP peptides
Search

VIP

0.97	Vasoactive intestinal polypeptide

0.76	GO:0070459	prolactin secretion
0.76	GO:0010469	regulation of receptor activity
0.72	GO:0048255	mRNA stabilization
0.60	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.60	GO:0019933	cAMP-mediated signaling
0.54	GO:0045732	positive regulation of protein catabolic process
0.54	GO:0032880	regulation of protein localization
0.45	GO:0007218	neuropeptide signaling pathway
0.43	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production
0.43	GO:0010562	positive regulation of phosphorus metabolic process

0.79	GO:0005179	hormone activity
0.44	GO:0051428	peptide hormone receptor binding
0.37	GO:0005057	signal transducer activity, downstream of receptor
0.36	GO:0031858	pituitary adenylate cyclase-activating polypeptide receptor binding

0.66	GO:0005576	extracellular region
0.38	GO:0005622	intracellular
0.38	GO:0097458	neuron part
0.37	GO:0044297	cell body
0.36	GO:0120025	plasma membrane bounded cell projection
0.34	GO:0044456	synapse part
0.34	GO:0044463	cell projection part
0.30	GO:0016020	membrane

sp|P32766|CST8_MOUSE
Cystatin-8
Search

CST8

0.69

Cystatin

0.76	GO:0010951	negative regulation of endopeptidase activity
0.59	GO:2000116	regulation of cysteine-type endopeptidase activity

0.83	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.60	GO:0002020	protease binding

0.64	GO:0009986	cell surface
0.58	GO:0005576	extracellular region
0.44	GO:0005737	cytoplasm

sp|P32848|PRVA_MOUSE
Parvalbumin alpha
Search

PVALB

0.85	Parvalbumin alpha

0.39

GO:0051480

regulation of cytosolic calcium ion concentration

0.70	GO:0005509	calcium ion binding
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0046982	protein heterodimerization activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0030424	axon
0.43	GO:0043679	axon terminus
0.42	GO:0036477	somatodendritic compartment
0.39	GO:0044297	cell body
0.38	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus
0.35	GO:0043234	protein complex
0.32	GO:0031514	motile cilium

sp|P32883|RASK_MOUSE
GTPase KRas
Search

KRAS

0.90	-Ha-ras Harvey rat sarcoma viral oncogene homolog b

0.61	GO:0007165	signal transduction
0.56	GO:0038002	endocrine signaling
0.55	GO:0021897	forebrain astrocyte development
0.54	GO:0035022	positive regulation of Rac protein signal transduction
0.53	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.53	GO:0060441	epithelial tube branching involved in lung morphogenesis
0.52	GO:0048873	homeostasis of number of cells within a tissue
0.52	GO:0032228	regulation of synaptic transmission, GABAergic
0.52	GO:0008542	visual learning
0.52	GO:0008284	positive regulation of cell proliferation

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.48	GO:0032403	protein complex binding
0.41	GO:0019002	GMP binding
0.40	GO:0030275	LRR domain binding
0.40	GO:0019003	GDP binding
0.36	GO:0042802	identical protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding

0.51	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.40	GO:0005737	cytoplasm
0.39	GO:0098857	membrane microdomain
0.36	GO:0005925	focal adhesion
0.35	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0020002	host cell plasma membrane
0.33	GO:0012505	endomembrane system

sp|P32921|SYWC_MOUSE
Tryptophan--tRNA ligase, cytoplasmic
Search

WARS

0.57	Tryptophanyl-tRNA synthetase

0.78	GO:0006436	tryptophanyl-tRNA aminoacylation
0.58	GO:0010835	regulation of protein ADP-ribosylation
0.53	GO:0045765	regulation of angiogenesis
0.53	GO:0006469	negative regulation of protein kinase activity
0.52	GO:0031334	positive regulation of protein complex assembly
0.49	GO:0010628	positive regulation of gene expression
0.40	GO:0001525	angiogenesis
0.34	GO:0008285	negative regulation of cell proliferation
0.34	GO:0031204	posttranslational protein targeting to membrane, translocation

0.78	GO:0004830	tryptophan-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0019210	kinase inhibitor activity
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0019901	protein kinase binding
0.51	GO:0019904	protein domain specific binding
0.51	GO:0042803	protein homodimerization activity

0.49	GO:0005737	cytoplasm
0.44	GO:0005634	nucleus
0.44	GO:0043234	protein complex
0.36	GO:0070062	extracellular exosome
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.78

EC:6.1.1.2

GO:0004830

sp|P32958|ROM1_MOUSE
Rod outer segment membrane protein 1
Search

ROM1

0.94	Retinal outer segment membrane protein 1

0.78	GO:0007601	visual perception
0.59	GO:0060041	retina development in camera-type eye
0.55	GO:0001754	eye photoreceptor cell differentiation
0.54	GO:0048593	camera-type eye morphogenesis
0.53	GO:0001944	vasculature development
0.46	GO:0007166	cell surface receptor signaling pathway
0.42	GO:0060255	regulation of macromolecule metabolic process
0.40	GO:0007155	cell adhesion
0.34	GO:1903525	regulation of membrane tubulation
0.34	GO:0009645	response to low light intensity stimulus

0.34	GO:0005515	protein binding
0.34	GO:0004637	phosphoribosylamine-glycine ligase activity

0.60	GO:0001750	photoreceptor outer segment
0.55	GO:0060170	ciliary membrane
0.44	GO:0005887	integral component of plasma membrane
0.33	GO:0055037	recycling endosome
0.33	GO:0005795	Golgi stack
0.33	GO:0005783	endoplasmic reticulum
0.32	GO:0043234	protein complex

0.34	EC:6.3.4.13	GO:0004637
0.34	KEGG:R04144	GO:0004637

sp|P32972|TNFL8_MOUSE
Tumor necrosis factor ligand superfamily member 8
Search

TNFSF8

0.96	Tumor necrosis factor ligand superfamily member 8

0.73	GO:0006955	immune response
0.73	GO:0043374	CD8-positive, alpha-beta T cell differentiation
0.69	GO:0050830	defense response to Gram-positive bacterium
0.62	GO:0045944	positive regulation of transcription by RNA polymerase II
0.57	GO:0010469	regulation of receptor activity
0.38	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.37	GO:0008283	cell proliferation
0.37	GO:0006915	apoptotic process
0.36	GO:0007267	cell-cell signaling

0.83	GO:0005164	tumor necrosis factor receptor binding
0.60	GO:0005125	cytokine activity

0.56	GO:0005615	extracellular space
0.35	GO:0005887	integral component of plasma membrane

sp|P33033|MC3R_MOUSE
Melanocortin receptor 3
Search

MC3R

0.97	Melanocortin receptor 3

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.54	GO:0019933	cAMP-mediated signaling
0.54	GO:0060259	regulation of feeding behavior
0.54	GO:0045475	locomotor rhythm
0.53	GO:0032922	circadian regulation of gene expression
0.41	GO:0042309	homoiothermy
0.40	GO:0055078	sodium ion homeostasis
0.39	GO:0002027	regulation of heart rate
0.39	GO:0008217	regulation of blood pressure
0.35	GO:0030819	positive regulation of cAMP biosynthetic process

0.84	GO:0004977	melanocortin receptor activity
0.55	GO:0042923	neuropeptide binding
0.40	GO:0042562	hormone binding
0.35	GO:0005515	protein binding
0.34	GO:0008188	neuropeptide receptor activity

0.54	GO:0005886	plasma membrane
0.37	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|P33146|CAD15_MOUSE
Cadherin-15
Search

CDH15

0.89	Putative cadherin egf lag seven-pass g-type receptor

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.43	GO:0007162	negative regulation of cell adhesion
0.42	GO:0055096	low-density lipoprotein particle mediated signaling
0.42	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.42	GO:0050678	regulation of epithelial cell proliferation
0.42	GO:0048514	blood vessel morphogenesis
0.42	GO:0051049	regulation of transport
0.42	GO:0043616	keratinocyte proliferation
0.42	GO:0016601	Rac protein signal transduction
0.42	GO:0031328	positive regulation of cellular biosynthetic process

0.70	GO:0005509	calcium ion binding
0.50	GO:0042802	identical protein binding
0.46	GO:0046983	protein dimerization activity
0.43	GO:0045296	cadherin binding
0.42	GO:0030169	low-density lipoprotein particle binding
0.41	GO:0045295	gamma-catenin binding
0.41	GO:0055100	adiponectin binding
0.40	GO:0032794	GTPase activating protein binding
0.40	GO:0030506	ankyrin binding
0.39	GO:0008013	beta-catenin binding

0.61	GO:0005901	caveola
0.58	GO:0031594	neuromuscular junction
0.52	GO:0005794	Golgi apparatus
0.50	GO:0005829	cytosol
0.41	GO:0005615	extracellular space
0.41	GO:0120025	plasma membrane bounded cell projection
0.40	GO:0098552	side of membrane
0.40	GO:0070161	anchoring junction
0.40	GO:0097458	neuron part
0.40	GO:0016342	catenin complex

sp|P33173|KIF1A_MOUSE
Kinesin-like protein KIF1A
Search

KIF1A

0.94	Kinesin family member 1Aa

0.74	GO:0007018	microtubule-based movement
0.47	GO:0030705	cytoskeleton-dependent intracellular transport
0.39	GO:0022027	interkinetic nuclear migration
0.36	GO:0006886	intracellular protein transport

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0042802	identical protein binding
0.41	GO:0016887	ATPase activity
0.36	GO:0046983	protein dimerization activity

0.47	GO:0005871	kinesin complex
0.38	GO:1904115	axon cytoplasm
0.37	GO:0008021	synaptic vesicle
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.37	GO:0098794	postsynapse
0.36	GO:0005874	microtubule
0.36	GO:0005829	cytosol

0.41

GO:0016887

sp|P33174|KIF4_MOUSE
Chromosome-associated kinesin KIF4
Search

KIF4A

0.96	Kinesin family member 4

0.74	GO:0007018	microtubule-based movement
0.48	GO:0051256	mitotic spindle midzone assembly
0.45	GO:0000281	mitotic cytokinesis
0.38	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.37	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.35	GO:0030705	cytoskeleton-dependent intracellular transport
0.34	GO:0006629	lipid metabolic process
0.33	GO:0022008	neurogenesis
0.33	GO:0030030	cell projection organization

0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0042623	ATPase activity, coupled
0.36	GO:0008889	glycerophosphodiester phosphodiesterase activity
0.35	GO:0003677	DNA binding

0.48	GO:0005871	kinesin complex
0.45	GO:0045171	intercellular bridge
0.44	GO:0030496	midbody
0.42	GO:0005874	microtubule
0.41	GO:0005654	nucleoplasm
0.37	GO:0016363	nuclear matrix
0.37	GO:0005694	chromosome
0.36	GO:0005829	cytosol
0.35	GO:1904115	axon cytoplasm
0.35	GO:0005819	spindle

0.36

EC:3.1.4.46

GO:0008889

sp|P33175|KIF5A_MOUSE
Kinesin heavy chain isoform 5A
Search

KIF5A

0.92	Neuronal kinesin heavy chain

0.74	GO:0007018	microtubule-based movement
0.59	GO:0030705	cytoskeleton-dependent intracellular transport
0.59	GO:0097120	receptor localization to synapse
0.50	GO:0016192	vesicle-mediated transport
0.48	GO:0120036	plasma membrane bounded cell projection organization
0.47	GO:0048667	cell morphogenesis involved in neuron differentiation
0.47	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.45	GO:0006935	chemotaxis
0.42	GO:0008104	protein localization
0.40	GO:0051654	establishment of mitochondrion localization

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.58	GO:0019894	kinesin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0042623	ATPase activity, coupled
0.41	GO:0016307	phosphatidylinositol phosphate kinase activity
0.37	GO:0097110	scaffold protein binding
0.35	GO:0032403	protein complex binding

0.60	GO:0035253	ciliary rootlet
0.59	GO:0032839	dendrite cytoplasm
0.55	GO:0043025	neuronal cell body
0.48	GO:0005871	kinesin complex
0.41	GO:0005874	microtubule
0.41	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0030424	axon
0.38	GO:0090724	central region of growth cone
0.37	GO:0097440	apical dendrite
0.36	GO:0005829	cytosol

0.41

GO:0016307

sp|P33215|NEDD1_MOUSE
Protein NEDD1
Search

NEDD1

0.97	Neural cell expressed developmentally down-regulated protein 1

0.71	GO:0071539	protein localization to centrosome
0.41	GO:0051301	cell division
0.41	GO:0007049	cell cycle
0.41	GO:0097711	ciliary basal body-plasma membrane docking
0.41	GO:0007019	microtubule depolymerization
0.39	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.39	GO:0070201	regulation of establishment of protein localization

0.36	GO:0005515	protein binding
0.33	GO:0043531	ADP binding

0.83	GO:0000242	pericentriolar material
0.79	GO:0036064	ciliary basal body
0.78	GO:0005814	centriole
0.75	GO:0000922	spindle pole
0.75	GO:0045177	apical part of cell
0.41	GO:0008274	gamma-tubulin ring complex
0.37	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P33242|STF1_MOUSE
Steroidogenic factor 1
Search

NR5A1

0.92	Steroidogenic factor 1 nuclear receptor

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.60	GO:2000195	negative regulation of female gonad development
0.59	GO:2000020	positive regulation of male gonad development
0.59	GO:0030325	adrenal gland development
0.59	GO:0001553	luteinization
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0051457	maintenance of protein location in nucleus
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:0008584	male gonad development

0.79	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0035326	enhancer binding
0.57	GO:0003682	chromatin binding
0.56	GO:0001012	RNA polymerase II regulatory region DNA binding
0.55	GO:0005543	phospholipid binding
0.54	GO:0003690	double-stranded DNA binding
0.49	GO:0019899	enzyme binding

0.61	GO:0005634	nucleus
0.56	GO:0005667	transcription factor complex
0.46	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm
0.35	GO:0043233	organelle lumen
0.33	GO:0005694	chromosome
0.33	GO:1905369	endopeptidase complex

sp|P33267|CP2F2_MOUSE
Cytochrome P450 2F2
Search

CYP2F1

0.87	Cytochrome P450 family 2 subfamily F member 1

0.58	GO:0019369	arachidonic acid metabolic process
0.53	GO:0090420	naphthalene-containing compound metabolic process
0.53	GO:0055114	oxidation-reduction process
0.43	GO:0009636	response to toxic substance
0.41	GO:0018979	trichloroethylene metabolic process
0.36	GO:0032501	multicellular organismal process
0.36	GO:0006587	serotonin biosynthetic process from tryptophan
0.35	GO:0042416	dopamine biosynthetic process
0.35	GO:0044703	multi-organism reproductive process
0.35	GO:0043651	linoleic acid metabolic process

0.72	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.58	GO:0019825	oxygen binding
0.58	GO:0008391	arachidonic acid monooxygenase activity
0.57	GO:0008395	steroid hydroxylase activity
0.35	GO:0071614	linoleic acid epoxygenase activity
0.34	GO:0005515	protein binding

0.42	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0031090	organelle membrane
0.32	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.72

EC:1.14.14

GO:0016712

sp|P33434|MMP2_MOUSE
72 kDa type IV collagenase
Search

MMP2

0.55	Matrix metalloproteinase

0.61	GO:0006508	proteolysis
0.45	GO:0001957	intramembranous ossification
0.45	GO:0060346	bone trabecula formation
0.44	GO:0001955	blood vessel maturation
0.44	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.44	GO:0030574	collagen catabolic process
0.44	GO:0060325	face morphogenesis
0.44	GO:0035987	endodermal cell differentiation
0.43	GO:0071230	cellular response to amino acid stimulus
0.42	GO:0001666	response to hypoxia

0.70	GO:0004222	metalloendopeptidase activity
0.62	GO:0008270	zinc ion binding
0.38	GO:0005509	calcium ion binding
0.36	GO:0016746	transferase activity, transferring acyl groups
0.30	GO:0004252	serine-type endopeptidase activity

0.74	GO:0031012	extracellular matrix
0.42	GO:0030017	sarcomere
0.40	GO:0005615	extracellular space
0.37	GO:0005739	mitochondrion
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane
0.30	GO:0005634	nucleus

0.70

GO:0004222

sp|P33435|MMP13_MOUSE
Collagenase 3
Search

MMP13

0.72	Matrix metalloproteinase

0.82	GO:0030574	collagen catabolic process
0.61	GO:0006508	proteolysis
0.59	GO:0022617	extracellular matrix disassembly
0.57	GO:0003417	growth plate cartilage development
0.56	GO:0001958	endochondral ossification
0.56	GO:0030282	bone mineralization
0.44	GO:0010727	negative regulation of hydrogen peroxide metabolic process
0.43	GO:0032461	positive regulation of protein oligomerization
0.42	GO:0030334	regulation of cell migration
0.42	GO:0044267	cellular protein metabolic process

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.56	GO:0005518	collagen binding
0.50	GO:0005509	calcium ion binding
0.37	GO:0004252	serine-type endopeptidase activity
0.36	GO:0001968	fibronectin binding
0.36	GO:0050750	low-density lipoprotein particle receptor binding
0.35	GO:0048306	calcium-dependent protein binding
0.34	GO:0001047	core promoter binding
0.32	GO:0043565	sequence-specific DNA binding

0.74	GO:0031012	extracellular matrix
0.40	GO:0005581	collagen trimer
0.37	GO:0005615	extracellular space
0.36	GO:0046581	intercellular canaliculus
0.35	GO:0005764	lysosome
0.34	GO:0005794	Golgi apparatus
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.70

GO:0004222

sp|P33534|OPRK_MOUSE
Kappa-type opioid receptor
Search

OPRK1

0.97	Kappa-type opioid receptor

0.85	GO:0038003	opioid receptor signaling pathway
0.57	GO:0019233	sensory perception of pain
0.57	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.57	GO:0046877	regulation of saliva secretion
0.52	GO:0051607	defense response to virus
0.52	GO:0007626	locomotory behavior
0.51	GO:0007218	neuropeptide signaling pathway
0.51	GO:0006955	immune response
0.46	GO:0007268	chemical synaptic transmission
0.43	GO:0043278	response to morphine

0.85	GO:0004985	opioid receptor activity
0.50	GO:0042923	neuropeptide binding
0.43	GO:0004977	melanocortin receptor activity
0.43	GO:0008188	neuropeptide receptor activity
0.43	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.36	GO:0005515	protein binding
0.34	GO:0005245	voltage-gated calcium channel activity

0.49	GO:0005887	integral component of plasma membrane
0.48	GO:0005829	cytosol
0.47	GO:0043005	neuron projection
0.45	GO:0005634	nucleus
0.41	GO:0043204	perikaryon
0.39	GO:0120038	plasma membrane bounded cell projection part
0.39	GO:0098793	presynapse
0.36	GO:0045203	integral component of cell outer membrane
0.33	GO:0005768	endosome

sp|P33587|PROC_MOUSE
Vitamin K-dependent protein C
Search

PROC

0.86	Vitamin K-dependent protein C

0.76	GO:0007596	blood coagulation
0.64	GO:1901552	positive regulation of endothelial cell development
0.63	GO:1903140	regulation of establishment of endothelial barrier
0.61	GO:0050819	negative regulation of coagulation
0.60	GO:0050728	negative regulation of inflammatory response
0.60	GO:0006508	proteolysis
0.60	GO:1900047	negative regulation of hemostasis
0.59	GO:0061045	negative regulation of wound healing
0.59	GO:0030193	regulation of blood coagulation
0.58	GO:0044537	regulation of circulating fibrinogen levels

0.68	GO:0004252	serine-type endopeptidase activity
0.66	GO:0005509	calcium ion binding
0.42	GO:0070012	oligopeptidase activity
0.39	GO:0043621	protein self-association
0.34	GO:0003677	DNA binding

0.63	GO:0005576	extracellular region
0.53	GO:0005794	Golgi apparatus
0.52	GO:0005783	endoplasmic reticulum
0.36	GO:0043233	organelle lumen
0.35	GO:0005634	nucleus
0.34	GO:0044446	intracellular organelle part

0.68

GO:0004252

sp|P33609|DPOLA_MOUSE
DNA polymerase alpha catalytic subunit
Search

POLA1

0.48	DNA polymerase alpha catalytic subunit

0.67	GO:0071897	DNA biosynthetic process
0.65	GO:0006260	DNA replication
0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.49	GO:0022616	DNA strand elongation
0.48	GO:0006303	double-strand break repair via nonhomologous end joining
0.41	GO:0070914	UV-damage excision repair
0.41	GO:0008283	cell proliferation
0.39	GO:0016070	RNA metabolic process
0.36	GO:0006289	nucleotide-excision repair
0.36	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle

0.71	GO:0008408	3'-5' exonuclease activity
0.71	GO:0003887	DNA-directed DNA polymerase activity
0.65	GO:0051539	4 iron, 4 sulfur cluster binding
0.64	GO:0001882	nucleoside binding
0.55	GO:0003677	DNA binding
0.53	GO:0046872	metal ion binding
0.52	GO:1901265	nucleoside phosphate binding
0.50	GO:0046982	protein heterodimerization activity
0.40	GO:0003682	chromatin binding
0.39	GO:0019901	protein kinase binding

0.60	GO:0005634	nucleus
0.53	GO:0000428	DNA-directed RNA polymerase complex
0.53	GO:0030894	replisome
0.50	GO:0031974	membrane-enclosed lumen
0.48	GO:0005829	cytosol
0.39	GO:0000785	chromatin
0.38	GO:0012505	endomembrane system
0.37	GO:0031967	organelle envelope
0.35	GO:0016035	zeta DNA polymerase complex

0.71

GO:0003887

sp|P33610|PRI2_MOUSE
DNA primase large subunit
Search

PRIM2

0.72	DNA primase large subunit

0.73	GO:0006269	DNA replication, synthesis of RNA primer
0.44	GO:0071897	DNA biosynthetic process
0.36	GO:0032201	telomere maintenance via semi-conservative replication
0.35	GO:0000082	G1/S transition of mitotic cell cycle
0.35	GO:0006270	DNA replication initiation

0.76	GO:0003896	DNA primase activity
0.63	GO:0051539	4 iron, 4 sulfur cluster binding
0.51	GO:0046872	metal ion binding
0.50	GO:0003677	DNA binding
0.45	GO:0003887	DNA-directed DNA polymerase activity
0.35	GO:0005515	protein binding

0.51	GO:0005658	alpha DNA polymerase:primase complex
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.76

EC:2.7.7

GO:0003896

sp|P33611|DPOA2_MOUSE
DNA polymerase alpha subunit B
Search

POLA2

0.74	DNA polymerase alpha subunit B

0.67	GO:0071897	DNA biosynthetic process
0.66	GO:0006260	DNA replication
0.60	GO:0000060	protein import into nucleus, translocation
0.35	GO:0000082	G1/S transition of mitotic cell cycle
0.35	GO:0000723	telomere maintenance
0.34	GO:0019725	cellular homeostasis
0.33	GO:0006508	proteolysis
0.33	GO:0048193	Golgi vesicle transport
0.33	GO:0043087	regulation of GTPase activity
0.32	GO:0055085	transmembrane transport

0.70	GO:0003887	DNA-directed DNA polymerase activity
0.55	GO:0046982	protein heterodimerization activity
0.54	GO:0003677	DNA binding
0.35	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.34	GO:0005509	calcium ion binding
0.32	GO:0022857	transmembrane transporter activity

0.62	GO:0005658	alpha DNA polymerase:primase complex
0.50	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.35	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0003887

sp|P33622|APOC3_MOUSE
Apolipoprotein C-III
Search

APOC3

0.97	Apolipoprotein C-III

0.78	GO:0010987	negative regulation of high-density lipoprotein particle clearance
0.76	GO:0010897	negative regulation of triglyceride catabolic process
0.76	GO:0010989	negative regulation of low-density lipoprotein particle clearance
0.76	GO:0010915	regulation of very-low-density lipoprotein particle clearance
0.75	GO:0042157	lipoprotein metabolic process
0.75	GO:0051005	negative regulation of lipoprotein lipase activity
0.74	GO:0006869	lipid transport
0.73	GO:0060621	negative regulation of cholesterol import
0.72	GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling
0.72	GO:0071830	triglyceride-rich lipoprotein particle clearance

0.76	GO:0070653	high-density lipoprotein particle receptor binding
0.72	GO:0008289	lipid binding
0.71	GO:0055102	lipase inhibitor activity
0.46	GO:0043168	anion binding
0.40	GO:0005319	lipid transporter activity
0.39	GO:0043178	alcohol binding
0.33	GO:0097159	organic cyclic compound binding

0.75	GO:0034363	intermediate-density lipoprotein particle
0.74	GO:0034366	spherical high-density lipoprotein particle
0.72	GO:0042627	chylomicron
0.72	GO:0034361	very-low-density lipoprotein particle
0.59	GO:0031012	extracellular matrix
0.44	GO:0070062	extracellular exosome
0.39	GO:0005769	early endosome
0.39	GO:0005829	cytosol

sp|P33680|GUC2A_MOUSE
Guanylin
Search

GUCA2A

0.97	Preprouroguanylin

0.86	GO:0031284	positive regulation of guanylate cyclase activity
0.38	GO:0007586	digestion
0.37	GO:0010469	regulation of receptor activity

0.86	GO:0030250	guanylate cyclase activator activity
0.38	GO:0005179	hormone activity

0.66	GO:0005576	extracellular region
0.40	GO:0031982	vesicle

sp|P33766|FPR1_MOUSE
fMet-Leu-Phe receptor
Search

0.96	Formyl peptide receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.55	GO:0002430	complement receptor mediated signaling pathway
0.52	GO:0050900	leukocyte migration
0.51	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.51	GO:0060326	cell chemotaxis
0.51	GO:0006954	inflammatory response
0.48	GO:1904646	cellular response to amyloid-beta
0.48	GO:0090026	positive regulation of monocyte chemotaxis
0.46	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.46	GO:0019722	calcium-mediated signaling

0.85	GO:0004982	N-formyl peptide receptor activity
0.55	GO:0004875	complement receptor activity
0.51	GO:0005124	scavenger receptor binding
0.39	GO:0050786	RAGE receptor binding
0.36	GO:0038024	cargo receptor activity

0.45	GO:0005887	integral component of plasma membrane
0.38	GO:0101003	ficolin-1-rich granule membrane
0.36	GO:0035577	azurophil granule membrane
0.35	GO:0035579	specific granule membrane
0.35	GO:0070821	tertiary granule membrane

sp|P33896|INAR1_MOUSE
Interferon alpha/beta receptor 1
Search

IFNAR1

0.96	Interferon alpha and beta receptor subunit 1

0.70	GO:0019221	cytokine-mediated signaling pathway
0.68	GO:0071357	cellular response to type I interferon
0.53	GO:0035457	cellular response to interferon-alpha
0.50	GO:0032496	response to lipopolysaccharide
0.48	GO:0045351	type I interferon biosynthetic process
0.47	GO:0050718	positive regulation of interleukin-1 beta secretion
0.47	GO:0032728	positive regulation of interferon-beta production
0.46	GO:0032729	positive regulation of interferon-gamma production
0.45	GO:0042110	T cell activation
0.45	GO:0050730	regulation of peptidyl-tyrosine phosphorylation

0.82	GO:0004904	interferon receptor activity
0.57	GO:0004920	interleukin-10 receptor activity
0.56	GO:0019962	type I interferon binding

0.53	GO:0005887	integral component of plasma membrane
0.46	GO:0005770	late endosome
0.46	GO:0005764	lysosome

sp|P34022|RANG_MOUSE
Ran-specific GTPase-activating protein
Search

RANBP1

0.89	RAN-binding protein 1

0.69	GO:0046907	intracellular transport
0.58	GO:0046604	positive regulation of mitotic centrosome separation
0.53	GO:0007051	spindle organization
0.49	GO:0000082	G1/S transition of mitotic cell cycle
0.48	GO:0006606	protein import into nucleus
0.46	GO:0043547	positive regulation of GTPase activity
0.46	GO:0006405	RNA export from nucleus
0.45	GO:0006511	ubiquitin-dependent protein catabolic process
0.39	GO:0072750	cellular response to leptomycin B
0.38	GO:0051592	response to calcium ion

0.48	GO:0008536	Ran GTPase binding
0.46	GO:0005096	GTPase activator activity
0.38	GO:0005092	GDP-dissociation inhibitor activity
0.38	GO:0045296	cadherin binding

0.52	GO:0005813	centrosome
0.44	GO:0005829	cytosol
0.41	GO:0005634	nucleus
0.38	GO:1904115	axon cytoplasm
0.33	GO:0012505	endomembrane system
0.33	GO:0031967	organelle envelope
0.30	GO:0031224	intrinsic component of membrane

sp|P34056|AP2A_MOUSE
Transcription factor AP-2-alpha
Search

TFAP2A

0.57	Transcription factor AP-2 alpha (Activating enhancer binding protein 2 alpha)

0.59	GO:0042472	inner ear morphogenesis
0.56	GO:0070172	positive regulation of tooth mineralization
0.56	GO:0010944	negative regulation of transcription by competitive promoter binding
0.56	GO:0043010	camera-type eye development
0.54	GO:0071281	cellular response to iron ion
0.54	GO:2000378	negative regulation of reactive oxygen species metabolic process
0.54	GO:0030501	positive regulation of bone mineralization
0.54	GO:0048646	anatomical structure formation involved in morphogenesis
0.54	GO:0060021	palate development
0.53	GO:0043525	positive regulation of neuron apoptotic process

0.60	GO:0003700	DNA binding transcription factor activity
0.53	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.51	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0003713	transcription coactivator activity
0.45	GO:0046983	protein dimerization activity
0.38	GO:0003682	chromatin binding
0.37	GO:0001106	RNA polymerase II transcription corepressor activity
0.37	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.37	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.34	GO:0042802	identical protein binding

0.60	GO:0005634	nucleus
0.50	GO:0005813	centrosome
0.47	GO:0005794	Golgi apparatus
0.46	GO:0005829	cytosol
0.45	GO:0070013	intracellular organelle lumen
0.34	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|P34057|RECO_MOUSE
Recoverin
Search

RCVRN

0.97	Recoverin a

0.57	GO:0009416	response to light stimulus
0.53	GO:0051924	regulation of calcium ion transport
0.52	GO:0007601	visual perception
0.51	GO:0009582	detection of abiotic stimulus
0.51	GO:0009581	detection of external stimulus
0.44	GO:0007165	signal transduction
0.35	GO:0031284	positive regulation of guanylate cyclase activity
0.33	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.33	GO:0051028	mRNA transport
0.33	GO:0006405	RNA export from nucleus

0.70	GO:0005509	calcium ion binding
0.35	GO:0008048	calcium sensitive guanylate cyclase activator activity
0.33	GO:0005515	protein binding
0.33	GO:0017171	serine hydrolase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0042626	ATPase activity, coupled to transmembrane movement of substances

0.40	GO:0030425	dendrite
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P34152|FAK1_MOUSE
Focal adhesion kinase 1
Search

PTK2

0.87	PTK2 protein tyrosine kinase 2 isoform b variant (Fragment)

0.85	GO:0007172	signal complex assembly
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.66	GO:2000811	negative regulation of anoikis
0.65	GO:0060396	growth hormone receptor signaling pathway
0.65	GO:0033628	regulation of cell adhesion mediated by integrin
0.64	GO:1900024	regulation of substrate adhesion-dependent cell spreading
0.64	GO:0090109	regulation of cell-substrate junction assembly
0.64	GO:1903391	regulation of adherens junction organization
0.64	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.63	GO:0051897	positive regulation of protein kinase B signaling

0.77	GO:0004713	protein tyrosine kinase activity
0.67	GO:0008432	JUN kinase binding
0.65	GO:0042169	SH2 domain binding
0.64	GO:0004871	signal transducer activity
0.56	GO:0003779	actin binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0005102	receptor binding

0.81	GO:0005925	focal adhesion
0.67	GO:0005856	cytoskeleton
0.59	GO:0030027	lamellipodium
0.58	GO:0016324	apical plasma membrane
0.53	GO:0005829	cytosol
0.49	GO:0005634	nucleus
0.48	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.47	GO:0044446	intracellular organelle part

0.77

GO:0004713

sp|P34821|BMP8A_MOUSE
Bone morphogenetic protein 8A
Search

0.82	bone morphogenetic protein 7

0.75	GO:0010469	regulation of receptor activity
0.57	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.57	GO:0060395	SMAD protein signal transduction
0.56	GO:0030509	BMP signaling pathway
0.53	GO:0043408	regulation of MAPK cascade
0.52	GO:0048468	cell development
0.51	GO:0042981	regulation of apoptotic process
0.45	GO:0002024	diet induced thermogenesis
0.45	GO:0001503	ossification
0.45	GO:2000505	regulation of energy homeostasis

0.77	GO:0008083	growth factor activity
0.58	GO:0070700	BMP receptor binding
0.55	GO:0005160	transforming growth factor beta receptor binding
0.53	GO:0005125	cytokine activity
0.36	GO:0008201	heparin binding
0.34	GO:0008410	CoA-transferase activity
0.33	GO:0008017	microtubule binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.65	GO:0005576	extracellular region
0.35	GO:0031982	vesicle
0.30	GO:0016020	membrane

0.34

EC:2.8.3

GO:0008410

sp|P34884|MIF_MOUSE
Macrophage migration inhibitory factor
Search

MIF

0.85	Macrophage migration inhibitory factor

0.79	GO:0010760	negative regulation of macrophage chemotaxis
0.78	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.78	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
0.77	GO:0010739	positive regulation of protein kinase A signaling
0.76	GO:0090344	negative regulation of cell aging
0.76	GO:0070207	protein homotrimerization
0.76	GO:0048146	positive regulation of fibroblast proliferation
0.75	GO:0071157	negative regulation of cell cycle arrest
0.75	GO:0046457	prostanoid biosynthetic process
0.75	GO:0030890	positive regulation of B cell proliferation

0.85	GO:0050178	phenylpyruvate tautomerase activity
0.84	GO:0004167	dopachrome isomerase activity
0.76	GO:0042056	chemoattractant activity
0.74	GO:0005125	cytokine activity
0.68	GO:0005126	cytokine receptor binding
0.66	GO:0002020	protease binding
0.64	GO:0042802	identical protein binding
0.49	GO:0042289	MHC class II protein binding
0.38	GO:0032403	protein complex binding
0.33	GO:0003676	nucleic acid binding

0.68	GO:0005615	extracellular space
0.66	GO:0009986	cell surface
0.65	GO:0043209	myelin sheath
0.61	GO:0005654	nucleoplasm
0.60	GO:0005829	cytosol
0.42	GO:1903561	extracellular vesicle
0.40	GO:1904813	ficolin-1-rich granule lumen
0.39	GO:0034774	secretory granule lumen

0.85	EC:5.3.2.1	GO:0050178
0.84	KEGG:R03673	GO:0004167

sp|P34902|IL2RG_MOUSE
Cytokine receptor common subunit gamma
Search

IL2RG

0.93	Common cytokine receptor gamma chain variant b

0.79	GO:0019221	cytokine-mediated signaling pathway
0.51	GO:0032831	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
0.50	GO:0033089	positive regulation of T cell differentiation in thymus
0.50	GO:0045579	positive regulation of B cell differentiation
0.44	GO:0010628	positive regulation of gene expression
0.39	GO:0098756	response to interleukin-21
0.39	GO:0071355	cellular response to interleukin-9
0.38	GO:0098761	cellular response to interleukin-7
0.38	GO:0071350	cellular response to interleukin-15
0.38	GO:0071352	cellular response to interleukin-2

0.80	GO:0004896	cytokine receptor activity
0.52	GO:0019976	interleukin-2 binding
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.33	GO:0019970	interleukin-11 binding
0.33	GO:0019981	interleukin-6 binding
0.33	GO:0005127	ciliary neurotrophic factor receptor binding
0.33	GO:0005138	interleukin-6 receptor binding

0.48	GO:0009897	external side of plasma membrane
0.36	GO:0005768	endosome
0.35	GO:0005829	cytosol
0.35	GO:0005887	integral component of plasma membrane
0.32	GO:0043025	neuronal cell body
0.32	GO:0030425	dendrite
0.32	GO:0098802	plasma membrane receptor complex

sp|P34914|HYES_MOUSE
Bifunctional epoxide hydrolase 2
Search

EPHX2

0.72	Soluble epoxide hydrolase

0.62	GO:0046272	stilbene catabolic process
0.61	GO:0097176	epoxide metabolic process
0.59	GO:0090181	regulation of cholesterol metabolic process
0.57	GO:0042632	cholesterol homeostasis
0.55	GO:0046839	phospholipid dephosphorylation
0.51	GO:0010628	positive regulation of gene expression
0.38	GO:0060841	venous blood vessel development
0.38	GO:0002539	prostaglandin production involved in inflammatory response
0.38	GO:0009636	response to toxic substance
0.38	GO:0033559	unsaturated fatty acid metabolic process

0.60	GO:0004301	epoxide hydrolase activity
0.59	GO:0042577	lipid phosphatase activity
0.56	GO:0015643	toxic substance binding
0.52	GO:0042803	protein homodimerization activity
0.51	GO:0005102	receptor binding
0.47	GO:0000287	magnesium ion binding
0.44	GO:0033885	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity

0.53	GO:0005777	peroxisome
0.49	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome

0.60	EC:3.3.2.10	GO:0004301
0.44	KEGG:R07582	GO:0033885

sp|P34927|ASGR1_MOUSE
Asialoglycoprotein receptor 1
Search

0.96	Asialoglycoprotein receptor 1

0.49	GO:0031668	cellular response to extracellular stimulus
0.47	GO:0055088	lipid homeostasis
0.46	GO:0031647	regulation of protein stability
0.45	GO:0009100	glycoprotein metabolic process
0.41	GO:0006897	endocytosis
0.38	GO:0030282	bone mineralization
0.37	GO:0018196	peptidyl-asparagine modification
0.36	GO:0043413	macromolecule glycosylation
0.34	GO:1901137	carbohydrate derivative biosynthetic process
0.34	GO:0007166	cell surface receptor signaling pathway

0.69	GO:0030246	carbohydrate binding
0.50	GO:0042803	protein homodimerization activity
0.45	GO:0004873	asialoglycoprotein receptor activity
0.35	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.34	GO:0005887	integral component of plasma membrane
0.34	GO:0005576	extracellular region

sp|P34928|APOC1_MOUSE
Apolipoprotein C-I
Search

APOC1

0.97	Apolipoprotein C-I, acidic form

0.75	GO:0042157	lipoprotein metabolic process
0.68	GO:0010900	negative regulation of phosphatidylcholine catabolic process
0.67	GO:0006869	lipid transport
0.66	GO:0034447	very-low-density lipoprotein particle clearance
0.66	GO:0010915	regulation of very-low-density lipoprotein particle clearance
0.65	GO:0071830	triglyceride-rich lipoprotein particle clearance
0.65	GO:0051005	negative regulation of lipoprotein lipase activity
0.65	GO:0010985	negative regulation of lipoprotein particle clearance
0.64	GO:0032375	negative regulation of cholesterol transport
0.64	GO:0048261	negative regulation of receptor-mediated endocytosis

0.63	GO:0004859	phospholipase inhibitor activity
0.62	GO:0005504	fatty acid binding
0.39	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity
0.39	GO:0031210	phosphatidylcholine binding

0.69	GO:0034361	very-low-density lipoprotein particle
0.62	GO:0034364	high-density lipoprotein particle
0.52	GO:0005783	endoplasmic reticulum
0.41	GO:0070062	extracellular exosome
0.39	GO:0042627	chylomicron

sp|P34960|MMP12_MOUSE
Macrophage metalloelastase
Search

MMP12

0.66	Macrophage metalloelastase

0.61	GO:0042060	wound healing
0.61	GO:0006508	proteolysis
0.57	GO:1902741	positive regulation of interferon-alpha secretion
0.57	GO:0060340	positive regulation of type I interferon-mediated signaling pathway
0.56	GO:0016477	cell migration
0.55	GO:0090504	epiboly
0.55	GO:0050691	regulation of defense response to virus by host
0.55	GO:0008284	positive regulation of cell proliferation
0.54	GO:0098586	cellular response to virus
0.54	GO:0030574	collagen catabolic process

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.54	GO:0005518	collagen binding
0.54	GO:0001047	core promoter binding
0.48	GO:0005509	calcium ion binding
0.46	GO:0043565	sequence-specific DNA binding
0.37	GO:0042802	identical protein binding
0.37	GO:0004252	serine-type endopeptidase activity
0.32	GO:0016746	transferase activity, transferring acyl groups

0.74	GO:0031012	extracellular matrix
0.53	GO:0005615	extracellular space
0.44	GO:0005634	nucleus
0.41	GO:0005887	integral component of plasma membrane
0.40	GO:0030017	sarcomere
0.36	GO:0005739	mitochondrion
0.35	GO:0042406	extrinsic component of endoplasmic reticulum membrane
0.33	GO:0005581	collagen trimer

0.70

GO:0004222

sp|P34968|5HT2C_MOUSE
5-hydroxytryptamine receptor 2C
Search

HTR2C

0.97	5-hydroxytryptamine (Serotonin) receptor 2C long isoform

0.82	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.81	GO:0007631	feeding behavior
0.78	GO:0007626	locomotory behavior
0.65	GO:0043397	regulation of corticotropin-releasing hormone secretion
0.64	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process
0.62	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
0.62	GO:0001662	behavioral fear response
0.61	GO:0032098	regulation of appetite
0.61	GO:0051209	release of sequestered calcium ion into cytosol
0.61	GO:0031644	regulation of neurological system process

0.82	GO:0099589	serotonin receptor activity
0.79	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.79	GO:0008227	G-protein coupled amine receptor activity
0.66	GO:0071886	1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
0.64	GO:0051378	serotonin binding
0.34	GO:0005515	protein binding

0.64	GO:0005887	integral component of plasma membrane
0.38	GO:0009897	external side of plasma membrane
0.33	GO:0005622	intracellular

sp|P34971|ADRB1_MOUSE
Beta-1 adrenergic receptor
Search

0.95	Beta-1 adrenergic receptor

0.84	GO:0071875	adrenergic receptor signaling pathway
0.82	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.73	GO:0045823	positive regulation of heart contraction
0.70	GO:0002025	norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
0.66	GO:0001659	temperature homeostasis
0.65	GO:0002024	diet induced thermogenesis
0.64	GO:0040015	negative regulation of multicellular organism growth
0.62	GO:0002027	regulation of heart rate
0.62	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine
0.61	GO:0043950	positive regulation of cAMP-mediated signaling

0.85	GO:0004939	beta-adrenergic receptor activity
0.64	GO:0031690	adrenergic receptor binding
0.63	GO:0051380	norepinephrine binding
0.57	GO:0051379	epinephrine binding
0.55	GO:0005057	signal transducer activity, downstream of receptor
0.55	GO:0030165	PDZ domain binding
0.54	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.52	GO:0046983	protein dimerization activity
0.47	GO:0042802	identical protein binding
0.37	GO:0050824	water binding

0.56	GO:0005769	early endosome
0.54	GO:0005886	plasma membrane
0.48	GO:0043235	receptor complex
0.36	GO:0005634	nucleus
0.35	GO:0098794	postsynapse
0.34	GO:0045177	apical part of cell
0.30	GO:0016021	integral component of membrane

0.34

EC:2.6.1

GO:0008483

sp|P34983|O1537_MOUSE
Olfactory receptor 1537
Search

0.46	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.40	GO:0051967	negative regulation of synaptic transmission, glutamatergic
0.40	GO:0051481	negative regulation of cytosolic calcium ion concentration
0.40	GO:0001963	synaptic transmission, dopaminergic
0.40	GO:0048148	behavioral response to cocaine
0.39	GO:0014059	regulation of dopamine secretion
0.39	GO:1901386	negative regulation of voltage-gated calcium channel activity
0.39	GO:0007194	negative regulation of adenylate cyclase activity
0.39	GO:0048149	behavioral response to ethanol

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.57	GO:0005549	odorant binding
0.40	GO:0035240	dopamine binding
0.37	GO:0030594	neurotransmitter receptor activity

0.55	GO:0005886	plasma membrane
0.39	GO:0030672	synaptic vesicle membrane
0.30	GO:0016021	integral component of membrane

sp|P34984|OLF13_MOUSE
Olfactory receptor 13
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:0032467	positive regulation of cytokinesis
0.34	GO:0032956	regulation of actin cytoskeleton organization

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.56	GO:0005886	plasma membrane
0.37	GO:0090543	Flemming body
0.37	GO:0097431	mitotic spindle pole
0.37	GO:0032154	cleavage furrow
0.37	GO:1990023	mitotic spindle midzone
0.36	GO:0055037	recycling endosome
0.30	GO:0016021	integral component of membrane

sp|P34985|OL143_MOUSE
Olfactory receptor 143
Search

0.46	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.57	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P34986|OLF6_MOUSE
Olfactory receptor 6
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.50	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P35123|UBP4_MOUSE
Ubiquitin carboxyl-terminal hydrolase 4
Search

USP4

0.92	Ubiquitin carboxyl-terminal hydrolase 4

0.76	GO:0016579	protein deubiquitination
0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.60	GO:0034394	protein localization to cell surface
0.59	GO:0000244	spliceosomal tri-snRNP complex assembly
0.59	GO:0031397	negative regulation of protein ubiquitination
0.56	GO:0031647	regulation of protein stability
0.44	GO:0034122	negative regulation of toll-like receptor signaling pathway
0.38	GO:0060389	pathway-restricted SMAD protein phosphorylation
0.37	GO:0030509	BMP signaling pathway
0.37	GO:0007179	transforming growth factor beta receptor signaling pathway

0.77	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.63	GO:0031685	adenosine receptor binding
0.53	GO:0042802	identical protein binding
0.39	GO:0061649	ubiquitin modification-dependent histone binding
0.38	GO:0005160	transforming growth factor beta receptor binding
0.38	GO:0046332	SMAD binding
0.36	GO:0004197	cysteine-type endopeptidase activity
0.35	GO:0046872	metal ion binding

0.51	GO:0005829	cytosol
0.48	GO:0005634	nucleus
0.44	GO:0005886	plasma membrane
0.35	GO:0005764	lysosome
0.32	GO:0005739	mitochondrion

0.36

EC:3.4.22

GO:0004197

sp|P35173|CYT3_MOUSE
Stefin-3
Search

CSTA

0.87	Leukocyte cysteine proteinase inhibitor 1

0.76	GO:0010951	negative regulation of endopeptidase activity
0.55	GO:0030216	keratinocyte differentiation
0.54	GO:0018149	peptide cross-linking
0.51	GO:0098609	cell-cell adhesion
0.37	GO:0008344	adult locomotory behavior
0.34	GO:0043043	peptide biosynthetic process
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process
0.33	GO:0032259	methylation

0.83	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.57	GO:0002020	protease binding
0.54	GO:0030674	protein binding, bridging
0.46	GO:0005198	structural molecule activity
0.33	GO:0008168	methyltransferase activity

0.57	GO:0001533	cornified envelope
0.52	GO:0005615	extracellular space
0.49	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.39	GO:0031012	extracellular matrix
0.36	GO:1903561	extracellular vesicle
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0044446	intracellular organelle part
0.33	GO:0030529	intracellular ribonucleoprotein complex

0.33

GO:0008168

sp|P35174|CYT2_MOUSE
Stefin-2
Search

0.76	Cystatin-A

0.76	GO:0010951	negative regulation of endopeptidase activity
0.47	GO:0030216	keratinocyte differentiation
0.47	GO:0018149	peptide cross-linking
0.45	GO:0098609	cell-cell adhesion
0.40	GO:0008344	adult locomotory behavior
0.34	GO:0032259	methylation
0.34	GO:0043043	peptide biosynthetic process
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process

0.82	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.53	GO:0002020	protease binding
0.49	GO:0030674	protein binding, bridging
0.42	GO:0005198	structural molecule activity
0.34	GO:0008168	methyltransferase activity

0.52	GO:0001533	cornified envelope
0.48	GO:0005615	extracellular space
0.45	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.42	GO:0031012	extracellular matrix
0.38	GO:1903561	extracellular vesicle
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0044446	intracellular organelle part

0.34

GO:0008168

sp|P35175|CYT1_MOUSE
Stefin-1
Search

CSTA

0.88	Leukocyte cysteine proteinase inhibitor

0.76	GO:0010951	negative regulation of endopeptidase activity
0.56	GO:0030216	keratinocyte differentiation
0.56	GO:0018149	peptide cross-linking
0.52	GO:0098609	cell-cell adhesion

0.83	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.57	GO:0002020	protease binding
0.55	GO:0030674	protein binding, bridging
0.46	GO:0005198	structural molecule activity

0.58	GO:0001533	cornified envelope
0.51	GO:0005615	extracellular space
0.49	GO:0005829	cytosol
0.46	GO:0005634	nucleus
0.37	GO:0031012	extracellular matrix
0.30	GO:0016021	integral component of membrane

sp|P35230|REG3B_MOUSE
Regenerating islet-derived protein 3-beta
Search

0.97	Pancreatic beta cell growth factor

0.67	GO:0044278	cell wall disruption in other organism
0.63	GO:0045617	negative regulation of keratinocyte differentiation
0.63	GO:0010838	positive regulation of keratinocyte proliferation
0.62	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.61	GO:0050830	defense response to Gram-positive bacterium
0.60	GO:0090303	positive regulation of wound healing
0.59	GO:0050829	defense response to Gram-negative bacterium
0.59	GO:0051715	cytolysis in other organism
0.59	GO:0006953	acute-phase response
0.51	GO:0002755	MyD88-dependent toll-like receptor signaling pathway

0.62	GO:0070492	oligosaccharide binding
0.56	GO:0042834	peptidoglycan binding
0.54	GO:0042802	identical protein binding
0.43	GO:0008083	growth factor activity
0.40	GO:0019838	growth factor binding
0.40	GO:0019903	protein phosphatase binding
0.37	GO:0046983	protein dimerization activity
0.37	GO:2001065	mannan binding
0.35	GO:0008201	heparin binding
0.33	GO:0008270	zinc ion binding

0.52	GO:0030141	secretory granule
0.52	GO:0005576	extracellular region
0.42	GO:0044216	other organism cell
0.41	GO:0032809	neuronal cell body membrane
0.41	GO:0032590	dendrite membrane
0.41	GO:0045178	basal part of cell
0.40	GO:0030426	growth cone
0.40	GO:0045177	apical part of cell
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0043234	protein complex

sp|P35235|PTN11_MOUSE
Tyrosine-protein phosphatase non-receptor type 11
Search

PTPN11

0.61	Tyrosine-protein phosphatase non-receptor type

0.73	GO:0035335	peptidyl-tyrosine dephosphorylation
0.60	GO:0051463	negative regulation of cortisol secretion
0.60	GO:0060125	negative regulation of growth hormone secretion
0.59	GO:0061582	intestinal epithelial cell migration
0.59	GO:0033277	abortive mitotic cell cycle
0.58	GO:0036302	atrioventricular canal development
0.58	GO:2001275	positive regulation of glucose import in response to insulin stimulus
0.58	GO:0033629	negative regulation of cell adhesion mediated by integrin
0.58	GO:0060020	Bergmann glial cell differentiation
0.57	GO:0071364	cellular response to epidermal growth factor stimulus

0.73	GO:0004725	protein tyrosine phosphatase activity
0.57	GO:0005158	insulin receptor binding
0.57	GO:0051428	peptide hormone receptor binding
0.56	GO:0005070	SH3/SH2 adaptor activity
0.55	GO:0030971	receptor tyrosine kinase binding
0.53	GO:0050839	cell adhesion molecule binding
0.40	GO:0031748	D1 dopamine receptor binding
0.40	GO:0043274	phospholipase binding
0.39	GO:0043560	insulin receptor substrate binding
0.37	GO:0019904	protein domain specific binding

0.45	GO:0005737	cytoplasm
0.45	GO:0005634	nucleus
0.44	GO:0043234	protein complex
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.73	EC:3.1.3.48	GO:0004725
0.36	KEGG:R04545	GO:0046934

sp|P35242|SFTPA_MOUSE
Pulmonary surfactant-associated protein A
Search

SFTPA1

0.89	Pulmonary surfactant-associated protein A

0.59	GO:0007585	respiratory gaseous exchange
0.52	GO:0008228	opsonization
0.46	GO:0002253	activation of immune response
0.45	GO:0033189	response to vitamin A
0.45	GO:0071732	cellular response to nitric oxide
0.44	GO:0055093	response to hyperoxia
0.44	GO:0070741	response to interleukin-6
0.44	GO:0070849	response to epidermal growth factor
0.44	GO:0050766	positive regulation of phagocytosis
0.44	GO:0071260	cellular response to mechanical stimulus

0.53	GO:0030246	carbohydrate binding
0.42	GO:0005201	extracellular matrix structural constituent
0.42	GO:0046872	metal ion binding
0.37	GO:0005319	lipid transporter activity
0.36	GO:0036094	small molecule binding
0.36	GO:0005515	protein binding
0.36	GO:0004478	methionine adenosyltransferase activity
0.35	GO:0042302	structural constituent of cuticle
0.34	GO:0044877	macromolecular complex binding
0.34	GO:0004867	serine-type endopeptidase inhibitor activity

0.72	GO:0005581	collagen trimer
0.55	GO:0005578	proteinaceous extracellular matrix
0.54	GO:0005615	extracellular space
0.44	GO:0005771	multivesicular body
0.43	GO:0005783	endoplasmic reticulum
0.43	GO:0042599	lamellar body
0.42	GO:0044420	extracellular matrix component
0.42	GO:0045334	clathrin-coated endocytic vesicle
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment

0.36

EC:2.5.1.6

GO:0004478

sp|P35276|RAB3D_MOUSE
Ras-related protein Rab-3D
Search

RAB3D

0.89	GTP-binding protein Rab-3D

0.57	GO:0018125	peptidyl-cysteine methylation
0.54	GO:0045453	bone resorption
0.53	GO:1903307	positive regulation of regulated secretory pathway
0.40	GO:0051944	positive regulation of catecholamine uptake involved in synaptic transmission
0.40	GO:0097494	regulation of vesicle size
0.40	GO:0051584	regulation of dopamine uptake involved in synaptic transmission
0.40	GO:0032226	positive regulation of synaptic transmission, dopaminergic
0.39	GO:2001025	positive regulation of response to drug
0.38	GO:0043270	positive regulation of ion transport
0.38	GO:0002376	immune system process

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.55	GO:0031489	myosin V binding
0.55	GO:0030742	GTP-dependent protein binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.34	GO:0008168	methyltransferase activity
0.32	GO:0046872	metal ion binding

0.54	GO:0042588	zymogen granule
0.51	GO:0005881	cytoplasmic microtubule
0.42	GO:0005739	mitochondrion
0.42	GO:0030133	transport vesicle
0.39	GO:0098793	presynapse
0.38	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0035577	azurophil granule membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.1.4.17

GO:0004114

sp|P35278|RAB5C_MOUSE
Ras-related protein Rab-5C
Search

RAB5C

0.90	RAB5C, member RAS oncogene family

0.70	GO:0048227	plasma membrane to endosome transport
0.57	GO:0030100	regulation of endocytosis
0.46	GO:0001702	gastrulation with mouth forming second
0.45	GO:0007032	endosome organization
0.45	GO:0001525	angiogenesis
0.44	GO:0098609	cell-cell adhesion
0.41	GO:0019882	antigen processing and presentation

0.68	GO:0003924	GTPase activity
0.66	GO:0019003	GDP binding
0.66	GO:0005525	GTP binding
0.45	GO:0030742	GTP-dependent protein binding

0.64	GO:0005768	endosome
0.61	GO:0005811	lipid droplet
0.53	GO:0030139	endocytic vesicle
0.44	GO:0070062	extracellular exosome
0.40	GO:0005886	plasma membrane
0.39	GO:0098993	anchored component of synaptic vesicle membrane
0.37	GO:0043231	intracellular membrane-bounded organelle

sp|P35279|RAB6A_MOUSE
Ras-related protein Rab-6A
Search

0.43	Putative rab subfamily protein of small gtpase

0.46	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.46	GO:0006891	intra-Golgi vesicle-mediated transport
0.46	GO:0042147	retrograde transport, endosome to Golgi
0.40	GO:0045467	R7 cell development
0.40	GO:0008103	oocyte microtubule cytoskeleton polarization
0.40	GO:0045451	pole plasm oskar mRNA localization
0.40	GO:0007293	germarium-derived egg chamber formation
0.39	GO:0072600	establishment of protein localization to Golgi
0.39	GO:0018125	peptidyl-cysteine methylation
0.39	GO:0050832	defense response to fungus

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0031489	myosin V binding
0.37	GO:0019904	protein domain specific binding
0.35	GO:0051117	ATPase binding
0.34	GO:0001671	ATPase activator activity

0.51	GO:0005794	Golgi apparatus
0.42	GO:0005829	cytosol
0.40	GO:0031410	cytoplasmic vesicle
0.38	GO:0098588	bounding membrane of organelle
0.37	GO:0031984	organelle subcompartment
0.36	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.36	GO:0070062	extracellular exosome
0.34	GO:0012506	vesicle membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0044432	endoplasmic reticulum part

sp|P35282|RAB21_MOUSE
Ras-related protein Rab-21
Search

RAB21

0.95	RAB21, member RAS oncogene family

0.54	GO:2000643	positive regulation of early endosome to late endosome transport
0.54	GO:0030100	regulation of endocytosis
0.53	GO:0050775	positive regulation of dendrite morphogenesis
0.50	GO:0017157	regulation of exocytosis
0.41	GO:0008089	anterograde axonal transport
0.40	GO:0030516	regulation of axon extension
0.37	GO:0015031	protein transport
0.32	GO:0043547	positive regulation of GTPase activity

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.34	GO:0005515	protein binding
0.32	GO:0005096	GTPase activator activity

0.55	GO:0098559	cytoplasmic side of early endosome membrane
0.50	GO:0032580	Golgi cisterna membrane
0.49	GO:0005802	trans-Golgi network
0.49	GO:0012506	vesicle membrane
0.49	GO:0043005	neuron projection
0.48	GO:0009898	cytoplasmic side of plasma membrane
0.40	GO:0032154	cleavage furrow
0.39	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.38	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0005925	focal adhesion

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

sp|P35283|RAB12_MOUSE
Ras-related protein Rab-12
Search

RAB12

0.96	RAB12, member RAS oncogene family

0.55	GO:0008333	endosome to lysosome transport
0.54	GO:0071346	cellular response to interferon-gamma
0.54	GO:0016239	positive regulation of macroautophagy
0.48	GO:0044257	cellular protein catabolic process
0.39	GO:0006914	autophagy
0.37	GO:0015031	protein transport
0.33	GO:0032869	cellular response to insulin stimulus
0.33	GO:0017157	regulation of exocytosis
0.33	GO:0006904	vesicle docking involved in exocytosis
0.33	GO:0002790	peptide secretion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.55	GO:0055038	recycling endosome membrane
0.53	GO:0005776	autophagosome
0.53	GO:0045335	phagocytic vesicle
0.51	GO:0005764	lysosome
0.43	GO:0005794	Golgi apparatus
0.39	GO:0098852	lytic vacuole membrane
0.37	GO:0031984	organelle subcompartment
0.36	GO:0030141	secretory granule
0.34	GO:0005829	cytosol
0.33	GO:0005769	early endosome

sp|P35285|RB22A_MOUSE
Ras-related protein Rab-22A
Search

RAB22A

0.97	Ras-related protein Rab-22A isoform B

0.58	GO:0097494	regulation of vesicle size
0.54	GO:0007032	endosome organization
0.53	GO:0006897	endocytosis
0.48	GO:0043001	Golgi to plasma membrane protein transport
0.47	GO:0090382	phagosome maturation
0.47	GO:0032869	cellular response to insulin stimulus
0.46	GO:0045055	regulated exocytosis
0.45	GO:0043112	receptor metabolic process
0.34	GO:0002283	neutrophil activation involved in immune response
0.34	GO:0002446	neutrophil mediated immunity

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.33	GO:0015035	protein disulfide oxidoreductase activity

0.59	GO:0045335	phagocytic vesicle
0.58	GO:0005769	early endosome
0.49	GO:0015629	actin cytoskeleton
0.48	GO:0032588	trans-Golgi network membrane
0.42	GO:0005886	plasma membrane
0.40	GO:0030666	endocytic vesicle membrane
0.38	GO:0005770	late endosome
0.38	GO:0010008	endosome membrane
0.38	GO:0001726	ruffle
0.37	GO:0070062	extracellular exosome

sp|P35288|RAB23_MOUSE
Ras-related protein Rab-23
Search

RAB23

0.97	RAB23, member RAS oncogene family

0.58	GO:0006968	cellular defense response
0.58	GO:0097094	craniofacial suture morphogenesis
0.57	GO:0000045	autophagosome assembly
0.57	GO:0042992	negative regulation of transcription factor import into nucleus
0.53	GO:0060271	cilium assembly
0.52	GO:0046039	GTP metabolic process
0.47	GO:0035469	determination of pancreatic left/right asymmetry
0.47	GO:0071910	determination of liver left/right asymmetry
0.47	GO:0003140	determination of left/right asymmetry in lateral mesoderm
0.45	GO:0061371	determination of heart left/right asymmetry

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.58	GO:0005776	autophagosome
0.55	GO:0045335	phagocytic vesicle
0.53	GO:0005813	centrosome
0.51	GO:0030054	cell junction
0.48	GO:0005829	cytosol
0.47	GO:0010008	endosome membrane
0.42	GO:0005886	plasma membrane
0.37	GO:0030666	endocytic vesicle membrane
0.36	GO:0070062	extracellular exosome

sp|P35290|RAB24_MOUSE
Ras-related protein Rab-24
Search

RAB24

0.95	Max dimerization protein 3

0.36	GO:0006914	autophagy
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0015031	protein transport

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding

0.58	GO:0005776	autophagosome
0.44	GO:0005739	mitochondrion
0.35	GO:0030667	secretory granule membrane
0.35	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane

sp|P35292|RAB17_MOUSE
Ras-related protein Rab-17
Search

RAB17

0.95	Ras-related protein Rab-17

0.47	GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor
0.46	GO:0046847	filopodium assembly
0.46	GO:0032456	endocytic recycling
0.45	GO:0032402	melanosome transport
0.45	GO:0051489	regulation of filopodium assembly
0.44	GO:0051963	regulation of synapse assembly
0.44	GO:0050773	regulation of dendrite development
0.43	GO:0060271	cilium assembly
0.42	GO:0030100	regulation of endocytosis
0.37	GO:0015031	protein transport

0.66	GO:0003924	GTPase activity
0.64	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding

0.46	GO:0055038	recycling endosome membrane
0.45	GO:0042470	melanosome
0.45	GO:0030139	endocytic vesicle
0.44	GO:0016323	basolateral plasma membrane
0.44	GO:0016324	apical plasma membrane
0.44	GO:0043025	neuronal cell body
0.43	GO:0030425	dendrite
0.43	GO:0005769	early endosome
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P35293|RAB18_MOUSE
Ras-related protein Rab-18
Search

RAB18

0.92	RAB18, member RAS oncogene family

0.62	GO:0034389	lipid particle organization
0.60	GO:0071786	endoplasmic reticulum tubular network organization
0.47	GO:0051170	nuclear import
0.39	GO:0001654	eye development
0.39	GO:0043009	chordate embryonic development
0.36	GO:0007420	brain development

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.58	GO:0071782	endoplasmic reticulum tubular network
0.46	GO:0005794	Golgi apparatus

sp|P35294|RAB19_MOUSE
Ras-related protein Rab-19
Search

RAB19

0.97	RAB19, member RAS oncogene family

0.46	GO:0035526	retrograde transport, plasma membrane to Golgi
0.44	GO:0090382	phagosome maturation
0.43	GO:0007030	Golgi organization
0.42	GO:0071346	cellular response to interferon-gamma
0.41	GO:1901998	toxin transport
0.40	GO:0019068	virion assembly

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0031410	cytoplasmic vesicle
0.47	GO:0005794	Golgi apparatus
0.37	GO:0070062	extracellular exosome
0.36	GO:0005886	plasma membrane
0.35	GO:0012506	vesicle membrane
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P35295|RAB20_MOUSE
Ras-related protein Rab-20
Search

RAB20

0.96	RAB20, member RAS oncogene family

0.76	GO:0090383	phagosome acidification
0.76	GO:0090385	phagosome-lysosome fusion
0.71	GO:0071346	cellular response to interferon-gamma
0.54	GO:0030100	regulation of endocytosis

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.70	GO:0045335	phagocytic vesicle
0.61	GO:0005794	Golgi apparatus
0.54	GO:0005769	early endosome
0.42	GO:0005886	plasma membrane

sp|P35329|CD22_MOUSE
B-cell receptor CD22
Search

CD22

0.84	B-cell receptor CD22

0.40	GO:0007155	cell adhesion
0.38	GO:0007166	cell surface receptor signaling pathway
0.33	GO:0048468	cell development
0.33	GO:0050765	negative regulation of phagocytosis
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0030182	neuron differentiation
0.33	GO:0120036	plasma membrane bounded cell projection organization
0.33	GO:0006955	immune response
0.32	GO:0075512	clathrin-dependent endocytosis of virus by host cell
0.32	GO:0031034	myosin filament assembly

0.41	GO:0015026	coreceptor activity
0.40	GO:0030246	carbohydrate binding
0.37	GO:0005515	protein binding
0.33	GO:0046790	virion binding
0.33	GO:0004930	G-protein coupled receptor activity
0.32	GO:0005509	calcium ion binding
0.32	GO:0097493	structural molecule activity conferring elasticity
0.32	GO:0008307	structural constituent of muscle
0.32	GO:0044877	macromolecular complex binding
0.32	GO:0004672	protein kinase activity

0.43	GO:0009897	external side of plasma membrane
0.39	GO:0005887	integral component of plasma membrane
0.39	GO:0070062	extracellular exosome
0.33	GO:0044853	plasma membrane raft
0.33	GO:0030139	endocytic vesicle
0.33	GO:0005770	late endosome
0.33	GO:0005769	early endosome
0.33	GO:0005764	lysosome
0.32	GO:0005859	muscle myosin complex
0.32	GO:0031430	M band

sp|P35330|ICAM2_MOUSE
Intercellular adhesion molecule 2
Search

ICAM2

0.97	Intercellular adhesion molecule 2

0.77	GO:0098609	cell-cell adhesion
0.46	GO:0006909	phagocytosis
0.38	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.38	GO:0030198	extracellular matrix organization

0.68

GO:0005178

integrin binding

0.66	GO:0001931	uropod
0.65	GO:0032154	cleavage furrow
0.63	GO:0005902	microvillus
0.54	GO:0005887	integral component of plasma membrane
0.41	GO:0070062	extracellular exosome

sp|P35343|CXCR2_MOUSE
C-X-C chemokine receptor type 2
Search

0.97	High affinity interleukin-8 receptor B

0.83	GO:0070098	chemokine-mediated signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.70	GO:0006935	chemotaxis
0.56	GO:0038112	interleukin-8-mediated signaling pathway
0.53	GO:0031623	receptor internalization
0.49	GO:0006968	cellular defense response
0.49	GO:0042119	neutrophil activation
0.49	GO:0050900	leukocyte migration
0.45	GO:0008284	positive regulation of cell proliferation
0.45	GO:0006955	immune response

0.85	GO:0016494	C-X-C chemokine receptor activity
0.79	GO:0019959	interleukin-8 binding
0.45	GO:0016493	C-C chemokine receptor activity
0.39	GO:0019957	C-C chemokine binding
0.37	GO:0051916	granulocyte colony-stimulating factor binding
0.34	GO:0005044	scavenger receptor activity
0.34	GO:0031727	CCR2 chemokine receptor binding
0.34	GO:0019960	C-X3-C chemokine binding
0.33	GO:0008289	lipid binding

0.48	GO:0042629	mast cell granule
0.46	GO:0009986	cell surface
0.40	GO:0005886	plasma membrane
0.38	GO:0097225	sperm midpiece
0.38	GO:0097228	sperm principal piece
0.37	GO:0030667	secretory granule membrane
0.36	GO:0098552	side of membrane
0.33	GO:0005576	extracellular region
0.32	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

sp|P35347|CRFR1_MOUSE
Corticotropin-releasing factor receptor 1
Search

CRHR1

0.95	Corticotrophin-releasing factor type 1 alpha receptor

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.49	GO:0051458	corticotropin secretion
0.49	GO:2000852	regulation of corticosterone secretion
0.49	GO:0071376	cellular response to corticotropin-releasing hormone stimulus
0.46	GO:0019933	cAMP-mediated signaling
0.45	GO:0051867	general adaptation syndrome, behavioral process
0.43	GO:0030325	adrenal gland development
0.43	GO:0042596	fear response
0.43	GO:0048149	behavioral response to ethanol

0.72	GO:0004930	G-protein coupled receptor activity
0.42	GO:0043404	corticotropin-releasing hormone receptor activity
0.40	GO:0051424	corticotropin-releasing hormone binding
0.40	GO:0001965	G-protein alpha-subunit binding
0.38	GO:0032403	protein complex binding

0.48	GO:0005886	plasma membrane
0.41	GO:0005768	endosome
0.39	GO:0043025	neuronal cell body
0.38	GO:0030425	dendrite
0.38	GO:0045177	apical part of cell
0.38	GO:0005802	trans-Golgi network
0.37	GO:0044309	neuron spine
0.36	GO:0098794	postsynapse
0.30	GO:0016021	integral component of membrane

sp|P35363|5HT2A_MOUSE
5-hydroxytryptamine receptor 2A
Search

HTR2A

0.97	5-hydroxytryptamine (Serotonin) receptor 2 A

0.81	GO:0006939	smooth muscle contraction
0.80	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.79	GO:0050795	regulation of behavior
0.78	GO:0046883	regulation of hormone secretion
0.60	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process
0.59	GO:0007202	activation of phospholipase C activity
0.57	GO:0051209	release of sequestered calcium ion into cytosol
0.57	GO:0014065	phosphatidylinositol 3-kinase signaling
0.57	GO:0045821	positive regulation of glycolytic process
0.56	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.80	GO:0099589	serotonin receptor activity
0.77	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.77	GO:0008227	G-protein coupled amine receptor activity
0.61	GO:0071886	1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
0.60	GO:0051378	serotonin binding
0.41	GO:0001965	G-protein alpha-subunit binding
0.39	GO:0032403	protein complex binding
0.36	GO:0018738	S-formylglutathione hydrolase activity
0.36	GO:0104005	hijacked molecular function

0.82	GO:0043198	dendritic shaft
0.63	GO:0005887	integral component of plasma membrane
0.45	GO:0005901	caveola
0.44	GO:0030424	axon
0.42	GO:0070852	cell body fiber
0.42	GO:0031410	cytoplasmic vesicle
0.40	GO:0043025	neuronal cell body
0.37	GO:0005829	cytosol

0.36	EC:3.1.2.12	GO:0018738
0.36	KEGG:R00527	GO:0018738

sp|P35374|AGTR2_MOUSE
Type-2 angiotensin II receptor
Search

AGTR2

0.97	Type-2 angiotensin II receptor

0.80	GO:0038166	angiotensin-activated signaling pathway
0.75	GO:0097746	regulation of blood vessel diameter
0.73	GO:0006954	inflammatory response
0.68	GO:0042981	regulation of apoptotic process
0.67	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway
0.66	GO:0032516	positive regulation of phosphoprotein phosphatase activity
0.62	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
0.62	GO:0035566	regulation of metanephros size
0.62	GO:0002035	brain renin-angiotensin system
0.62	GO:0003072	renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure

0.83	GO:0004945	angiotensin type II receptor activity
0.52	GO:0001626	nociceptin receptor activity
0.42	GO:0042277	peptide binding
0.40	GO:0042562	hormone binding
0.38	GO:0008134	transcription factor binding
0.38	GO:0016520	growth hormone-releasing hormone receptor activity
0.37	GO:0001965	G-protein alpha-subunit binding
0.36	GO:0048019	receptor antagonist activity
0.36	GO:0050254	rhodopsin kinase activity
0.35	GO:0008022	protein C-terminus binding

0.40	GO:0005887	integral component of plasma membrane
0.39	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0043005	neuron projection
0.36	GO:0031410	cytoplasmic vesicle
0.34	GO:0005576	extracellular region
0.33	GO:0012505	endomembrane system
0.32	GO:0005654	nucleoplasm

0.36

GO:0050254

sp|P35375|PE2R1_MOUSE
Prostaglandin E2 receptor EP1 subtype
Search

PTGER1

0.97	Prostaglandin E receptor 1

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.66	GO:0032496	response to lipopolysaccharide
0.48	GO:0071798	response to prostaglandin D
0.47	GO:0071379	cellular response to prostaglandin stimulus
0.47	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.46	GO:0032355	response to estradiol
0.44	GO:0008284	positive regulation of cell proliferation
0.44	GO:0043066	negative regulation of apoptotic process
0.42	GO:0010628	positive regulation of gene expression
0.34	GO:0007567	parturition

0.85	GO:0004955	prostaglandin receptor activity
0.53	GO:0004960	thromboxane receptor activity

0.41	GO:0005886	plasma membrane
0.40	GO:0005576	extracellular region
0.36	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|P35377|OPRX_MOUSE
Nociceptin receptor
Search

OPRL1

0.97	Nociceptin receptor

0.86	GO:0038003	opioid receptor signaling pathway
0.64	GO:0019233	sensory perception of pain
0.62	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.59	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.49	GO:0007218	neuropeptide signaling pathway
0.47	GO:0007268	chemical synaptic transmission
0.44	GO:0060454	positive regulation of gastric acid secretion
0.44	GO:1904058	positive regulation of sensory perception of pain
0.43	GO:0044849	estrous cycle
0.43	GO:0106072	negative regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway

0.87	GO:0001626	nociceptin receptor activity
0.52	GO:0042923	neuropeptide binding
0.41	GO:0008022	protein C-terminus binding

0.52	GO:0005887	integral component of plasma membrane
0.47	GO:0043005	neuron projection
0.41	GO:0031410	cytoplasmic vesicle

sp|P35378|FSHR_MOUSE
Follicle-stimulating hormone receptor
Search

FSHR

0.83	Follicle-stimulating hormone receptor

0.86	GO:0042699	follicle-stimulating hormone signaling pathway
0.64	GO:0001545	primary ovarian follicle growth
0.60	GO:0060408	regulation of acetylcholine metabolic process
0.60	GO:0045670	regulation of osteoclast differentiation
0.59	GO:0060011	Sertoli cell proliferation
0.59	GO:0009992	cellular water homeostasis
0.58	GO:0035093	spermatogenesis, exchange of chromosomal proteins
0.58	GO:0045779	negative regulation of bone resorption
0.58	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
0.58	GO:0060009	Sertoli cell development

0.86	GO:0004963	follicle-stimulating hormone receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.45	GO:0001653	peptide receptor activity
0.41	GO:0017046	peptide hormone binding
0.35	GO:0005515	protein binding

0.54	GO:0005886	plasma membrane
0.51	GO:0009986	cell surface
0.39	GO:0005768	endosome
0.30	GO:0016021	integral component of membrane

sp|P35383|P2RY2_MOUSE
P2Y purinoceptor 2
Search

P2RY2

0.97	Purinergic receptor P2Y, G-protein coupled, 2

0.85	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway
0.78	GO:0070257	positive regulation of mucus secretion
0.74	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.71	GO:0097746	regulation of blood vessel diameter
0.67	GO:0030321	transepithelial chloride transport
0.50	GO:0071380	cellular response to prostaglandin E stimulus
0.37	GO:0006873	cellular ion homeostasis
0.37	GO:0060406	positive regulation of penile erection
0.36	GO:0032308	positive regulation of prostaglandin secretion
0.36	GO:0071415	cellular response to purine-containing compound

0.85	GO:0045028	G-protein coupled purinergic nucleotide receptor activity
0.53	GO:0045030	UTP-activated nucleotide receptor activity
0.37	GO:0031686	A1 adenosine receptor binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0019103	pyrimidine nucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0016323	basolateral plasma membrane
0.39	GO:0016324	apical plasma membrane
0.35	GO:0005769	early endosome
0.35	GO:0005764	lysosome
0.35	GO:0005887	integral component of plasma membrane
0.33	GO:0005739	mitochondrion

sp|P35385|HSPB7_MOUSE
Heat shock protein beta-7
Search

HSPB7

0.97	Heat shock protein beta-7

0.78	GO:0007507	heart development
0.47	GO:0071907	determination of digestive tract left/right asymmetry
0.47	GO:0070121	Kupffer's vesicle development
0.47	GO:0060972	left/right pattern formation
0.44	GO:0048568	embryonic organ development
0.44	GO:0002009	morphogenesis of an epithelium
0.44	GO:0048598	embryonic morphogenesis
0.44	GO:0016477	cell migration
0.43	GO:0048646	anatomical structure formation involved in morphogenesis
0.36	GO:0008016	regulation of heart contraction

0.60	GO:0031005	filamin binding
0.36	GO:0008022	protein C-terminus binding

0.61	GO:0016235	aggresome
0.52	GO:0015629	actin cytoskeleton
0.52	GO:0005654	nucleoplasm
0.46	GO:0005739	mitochondrion

sp|P35396|PPARD_MOUSE
Peroxisome proliferator-activated receptor delta
Search

PPARD

0.96	Peroxisome proliferator-activated receptor delta b

0.78	GO:0030522	intracellular receptor signaling pathway
0.77	GO:0043401	steroid hormone mediated signaling pathway
0.60	GO:0051546	keratinocyte migration
0.59	GO:0043415	positive regulation of skeletal muscle tissue regeneration
0.59	GO:2000288	positive regulation of myoblast proliferation
0.59	GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II
0.59	GO:0043616	keratinocyte proliferation
0.58	GO:0014842	regulation of skeletal muscle satellite cell proliferation
0.58	GO:0045662	negative regulation of myoblast differentiation
0.57	GO:0060612	adipose tissue development

0.81	GO:0004879	nuclear receptor activity
0.78	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0070539	linoleic acid binding
0.62	GO:0008270	zinc ion binding
0.55	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.51	GO:0008134	transcription factor binding
0.51	GO:0046982	protein heterodimerization activity
0.42	GO:0008144	drug binding
0.41	GO:0003713	transcription coactivator activity

0.61	GO:0005634	nucleus
0.50	GO:0000785	chromatin
0.48	GO:0070013	intracellular organelle lumen

sp|P35412|GPR12_MOUSE
G-protein coupled receptor 12
Search

GPR12

0.66	G-protein coupled receptor

0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.55	GO:0006874	cellular calcium ion homeostasis
0.43	GO:0090520	sphingolipid mediated signaling pathway
0.35	GO:0040020	regulation of meiotic nuclear division

0.70	GO:0004930	G-protein coupled receptor activity
0.56	GO:0031210	phosphatidylcholine binding

0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P35413|GPR3_MOUSE
G-protein coupled receptor 3
Search

GPR3

0.65	G-protein coupled receptor

0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.56	GO:0040020	regulation of meiotic nuclear division
0.50	GO:0090520	sphingolipid mediated signaling pathway
0.49	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.37	GO:0030816	positive regulation of cAMP metabolic process
0.37	GO:0019933	cAMP-mediated signaling
0.36	GO:1904145	negative regulation of meiotic cell cycle process involved in oocyte maturation
0.35	GO:0008285	negative regulation of cell proliferation

0.70	GO:0004930	G-protein coupled receptor activity
0.36	GO:0031210	phosphatidylcholine binding
0.33	GO:0005515	protein binding

0.36	GO:0005886	plasma membrane
0.35	GO:0031965	nuclear membrane
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|P35419|PERT_MOUSE
Thyroid peroxidase
Search

TPO

0.97	homologue of mammlian thyroid peroxidase precursor

0.84	GO:0006590	thyroid hormone generation
0.68	GO:0006979	response to oxidative stress
0.66	GO:0098869	cellular oxidant detoxification
0.58	GO:0035162	embryonic hemopoiesis
0.51	GO:0055114	oxidation-reduction process
0.42	GO:0042446	hormone biosynthetic process
0.42	GO:0042744	hydrogen peroxide catabolic process
0.37	GO:1902170	cellular response to reactive nitrogen species
0.37	GO:0097366	response to bronchodilator
0.36	GO:0071241	cellular response to inorganic substance

0.85	GO:0004447	iodide peroxidase activity
0.63	GO:0005509	calcium ion binding
0.60	GO:0020037	heme binding

0.46	GO:0005615	extracellular space
0.45	GO:0005739	mitochondrion
0.37	GO:0009986	cell surface
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.85

EC:1.11.1.8

GO:0004447

sp|P35428|HES1_MOUSE
Transcription factor HES-1
Search

HES1

0.91	BHLH-WRPW transcription factor

0.59	GO:0061106	negative regulation of stomach neuroendocrine cell differentiation
0.59	GO:2000974	negative regulation of pro-B cell differentiation
0.58	GO:0007262	STAT protein import into nucleus
0.58	GO:2000227	negative regulation of pancreatic A cell differentiation
0.58	GO:0021536	diencephalon development
0.58	GO:0007219	Notch signaling pathway
0.58	GO:0072141	renal interstitial fibroblast development
0.58	GO:0006351	transcription, DNA-templated
0.58	GO:0035910	ascending aorta morphogenesis
0.58	GO:0045977	positive regulation of mitotic cell cycle, embryonic

0.68	GO:0046983	protein dimerization activity
0.59	GO:0071820	N-box binding
0.54	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0042826	histone deacetylase binding
0.50	GO:0051087	chaperone binding
0.50	GO:0042802	identical protein binding
0.40	GO:0008134	transcription factor binding
0.36	GO:0008432	JUN kinase binding
0.36	GO:0070888	E-box binding
0.35	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0005694	chromosome
0.30	GO:0016020	membrane

0.34

EC:3.2.1.23

GO:0004565

sp|P35436|NMDE1_MOUSE
Glutamate receptor ionotropic, NMDA 2A
Search

GRIN2A

0.97	Glutamate ionotropic receptor NMDA type subunit 2A

0.78	GO:0060079	excitatory postsynaptic potential
0.75	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0034220	ion transmembrane transport
0.58	GO:0033058	directional locomotion
0.57	GO:1900273	positive regulation of long-term synaptic potentiation
0.56	GO:0051930	regulation of sensory perception of pain
0.56	GO:0001975	response to amphetamine
0.56	GO:0042428	serotonin metabolic process
0.56	GO:0042417	dopamine metabolic process
0.56	GO:0001964	startle response

0.80	GO:0005234	extracellularly glutamate-gated ion channel activity
0.75	GO:0004970	ionotropic glutamate receptor activity
0.55	GO:0099604	ligand-gated calcium channel activity
0.52	GO:0022843	voltage-gated cation channel activity
0.39	GO:0042165	neurotransmitter binding
0.38	GO:0016597	amino acid binding
0.37	GO:0008270	zinc ion binding
0.36	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding
0.34	GO:0098772	molecular function regulator

0.76	GO:0098794	postsynapse
0.72	GO:0097060	synaptic membrane
0.67	GO:0030054	cell junction
0.59	GO:0017146	NMDA selective glutamate receptor complex
0.54	GO:0032279	asymmetric synapse
0.53	GO:0008021	synaptic vesicle
0.51	GO:0043005	neuron projection
0.50	GO:0009986	cell surface
0.48	GO:0005783	endoplasmic reticulum
0.42	GO:0044422	organelle part

sp|P35438|NMDZ1_MOUSE
Glutamate receptor ionotropic, NMDA 1
Search

GRIN1

0.93	Glutamate ionotropic receptor NMDA type subunit 1

0.77	GO:0060079	excitatory postsynaptic potential
0.74	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0034220	ion transmembrane transport
0.54	GO:0018964	propylene metabolic process
0.53	GO:0021586	pons maturation
0.53	GO:0001661	conditioned taste aversion
0.52	GO:1905429	response to glycine
0.52	GO:0060134	prepulse inhibition
0.52	GO:0043278	response to morphine
0.52	GO:0008355	olfactory learning

0.79	GO:0005234	extracellularly glutamate-gated ion channel activity
0.75	GO:0004970	ionotropic glutamate receptor activity
0.53	GO:0016594	glycine binding
0.51	GO:0016595	glutamate binding
0.51	GO:0099094	ligand-gated cation channel activity
0.49	GO:1904315	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
0.49	GO:0022843	voltage-gated cation channel activity
0.49	GO:0005262	calcium channel activity
0.48	GO:0005516	calmodulin binding
0.46	GO:0005102	receptor binding

0.76	GO:0045211	postsynaptic membrane
0.72	GO:0030054	cell junction
0.54	GO:0017146	NMDA selective glutamate receptor complex
0.50	GO:0043197	dendritic spine
0.50	GO:0014069	postsynaptic density
0.49	GO:0008021	synaptic vesicle
0.47	GO:0009986	cell surface
0.45	GO:0005783	endoplasmic reticulum
0.40	GO:0044422	organelle part
0.38	GO:0043083	synaptic cleft

sp|P35441|TSP1_MOUSE
Thrombospondin-1
Search

THBS1

0.67	Thrombospondin 1

0.84	GO:0016525	negative regulation of angiogenesis
0.81	GO:0030198	extracellular matrix organization
0.80	GO:0006954	inflammatory response
0.71	GO:0007155	cell adhesion
0.62	GO:0002605	negative regulation of dendritic cell antigen processing and presentation
0.61	GO:0010754	negative regulation of cGMP-mediated signaling
0.61	GO:0010751	negative regulation of nitric oxide mediated signal transduction
0.61	GO:2001027	negative regulation of endothelial cell chemotaxis
0.61	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport
0.60	GO:0010757	negative regulation of plasminogen activation

0.84	GO:0050840	extracellular matrix binding
0.83	GO:0008201	heparin binding
0.69	GO:0005509	calcium ion binding
0.61	GO:0070052	collagen V binding
0.61	GO:0070051	fibrinogen binding
0.59	GO:0030169	low-density lipoprotein particle binding
0.59	GO:0001968	fibronectin binding
0.58	GO:0017134	fibroblast growth factor binding
0.58	GO:0001786	phosphatidylserine binding
0.57	GO:0005178	integrin binding

0.74	GO:0031012	extracellular matrix
0.73	GO:0005615	extracellular space
0.58	GO:0031091	platelet alpha granule
0.55	GO:0009897	external side of plasma membrane
0.44	GO:0043234	protein complex
0.36	GO:0016529	sarcoplasmic reticulum
0.34	GO:1903561	extracellular vesicle
0.33	GO:0034774	secretory granule lumen
0.33	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

sp|P35454|NEU1_MOUSE
Oxytocin-neurophysin 1
Search

OXT

0.96	Prepropeptide for oxytocin and neurophysin

0.76	GO:0010469	regulation of receptor activity
0.52	GO:0032094	response to food
0.50	GO:0070528	protein kinase C signaling
0.50	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.49	GO:0070371	ERK1 and ERK2 cascade
0.48	GO:0009612	response to mechanical stimulus
0.48	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.48	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.46	GO:0006915	apoptotic process
0.45	GO:0002125	maternal aggressive behavior

0.86	GO:0005185	neurohypophyseal hormone activity
0.53	GO:0031894	V1A vasopressin receptor binding
0.49	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.44	GO:0031855	oxytocin receptor binding
0.41	GO:0004871	signal transducer activity
0.41	GO:0004672	protein kinase activity
0.40	GO:0031895	V1B vasopressin receptor binding
0.36	GO:0031896	V2 vasopressin receptor binding
0.34	GO:0052795	exo-alpha-(2->6)-sialidase activity
0.34	GO:0052796	exo-alpha-(2->8)-sialidase activity

0.66	GO:0005576	extracellular region
0.42	GO:0030141	secretory granule
0.42	GO:0043005	neuron projection
0.41	GO:0120038	plasma membrane bounded cell projection part
0.40	GO:0098793	presynapse
0.38	GO:0036477	somatodendritic compartment
0.34	GO:0030665	clathrin-coated vesicle membrane
0.34	GO:0044297	cell body
0.33	GO:0005829	cytosol
0.30	GO:0044425	membrane part

0.34

EC:3.2.1.18

GO:0052795

sp|P35455|NEU2_MOUSE
Vasopressin-neurophysin 2-copeptin
Search

0.96	Prepropeptide for oxytocin and neurophysin

0.75	GO:0010469	regulation of receptor activity
0.52	GO:0070528	protein kinase C signaling
0.52	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.51	GO:0070371	ERK1 and ERK2 cascade
0.50	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.50	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.49	GO:0032094	response to food
0.47	GO:0006915	apoptotic process
0.46	GO:0009612	response to mechanical stimulus
0.45	GO:0008015	blood circulation

0.86	GO:0005185	neurohypophyseal hormone activity
0.55	GO:0031894	V1A vasopressin receptor binding
0.51	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.42	GO:0004871	signal transducer activity
0.42	GO:0004672	protein kinase activity
0.42	GO:0031895	V1B vasopressin receptor binding
0.42	GO:0031855	oxytocin receptor binding
0.37	GO:0031896	V2 vasopressin receptor binding
0.33	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0052795	exo-alpha-(2->6)-sialidase activity

0.66	GO:0005576	extracellular region
0.44	GO:0043005	neuron projection
0.43	GO:0120038	plasma membrane bounded cell projection part
0.42	GO:0030141	secretory granule
0.42	GO:0036477	somatodendritic compartment
0.39	GO:0044297	cell body
0.38	GO:0098793	presynapse
0.35	GO:0030665	clathrin-coated vesicle membrane
0.34	GO:0005829	cytosol
0.30	GO:0044425	membrane part

0.33	EC:3.2.1.18	GO:0052795
0.33	KEGG:R03876	GO:0004842

sp|P35456|UPAR_MOUSE
Urokinase plasminogen activator surface receptor
Search

PLAUR

0.97	Urokinase plasminogen activator surface receptor

0.87	GO:0038195	urokinase plasminogen activator signaling pathway
0.74	GO:0030162	regulation of proteolysis
0.70	GO:0090200	positive regulation of release of cytochrome c from mitochondria
0.70	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
0.68	GO:0043388	positive regulation of DNA binding
0.68	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.62	GO:0001934	positive regulation of protein phosphorylation
0.60	GO:0051346	negative regulation of hydrolase activity
0.58	GO:0032269	negative regulation of cellular protein metabolic process
0.47	GO:0016310	phosphorylation

0.87	GO:0030377	urokinase plasminogen activator receptor activity
0.62	GO:0019904	protein domain specific binding
0.59	GO:0005102	receptor binding
0.58	GO:0019899	enzyme binding
0.49	GO:0016301	kinase activity

0.61	GO:0009986	cell surface
0.55	GO:0005887	integral component of plasma membrane
0.50	GO:0031225	anchored component of membrane
0.49	GO:0071438	invadopodium membrane
0.45	GO:0030054	cell junction
0.41	GO:0070062	extracellular exosome
0.39	GO:0045177	apical part of cell
0.39	GO:0035579	specific granule membrane
0.38	GO:0005788	endoplasmic reticulum lumen
0.36	GO:0019898	extrinsic component of membrane

sp|P35459|LY6D_MOUSE
Lymphocyte antigen 6D
Search

LY6D

0.97	Lymphocyte antigen 6 family member D

0.85	GO:0035634	response to stilbenoid
0.77	GO:0030098	lymphocyte differentiation
0.43	GO:0006501	C-terminal protein lipidation
0.40	GO:0007155	cell adhesion
0.37	GO:0001971	negative regulation of activation of membrane attack complex

0.71	GO:0009986	cell surface
0.51	GO:0031225	anchored component of membrane
0.41	GO:0005886	plasma membrane
0.38	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|P35460|LY6F_MOUSE
Lymphocyte antigen 6F
Search

0.97	Lymphocyte antigen 6F

0.43

GO:0005515

protein binding

0.76	GO:0031225	anchored component of membrane
0.64	GO:0009897	external side of plasma membrane
0.37	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|P35461|LY6G_MOUSE
Lymphocyte antigen 6G (Fragment)
Search

0.97	Lymphocyte antigen 6G

0.43

GO:0005515

protein binding

0.80	GO:0031225	anchored component of membrane
0.66	GO:0009897	external side of plasma membrane
0.36	GO:0005622	intracellular

sp|P35486|ODPA_MOUSE
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
Search

PDHA1

0.52	Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial

0.79	GO:0006086	acetyl-CoA biosynthetic process from pyruvate
0.52	GO:0055114	oxidation-reduction process
0.45	GO:0006101	citrate metabolic process
0.42	GO:0019362	pyridine nucleotide metabolic process
0.41	GO:0006091	generation of precursor metabolites and energy
0.41	GO:0006006	glucose metabolic process
0.37	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate

0.78	GO:0004738	pyruvate dehydrogenase activity
0.75	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
0.45	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0005515	protein binding

0.55	GO:0043231	intracellular membrane-bounded organelle
0.49	GO:0045254	pyruvate dehydrogenase complex
0.47	GO:0043209	myelin sheath
0.47	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.42	GO:0043232	intracellular non-membrane-bounded organelle

0.75

EC:1.2.4

GO:0016624

sp|P35487|ODPAT_MOUSE
Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
Search

PDHA1

0.52	Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial

0.80	GO:0006086	acetyl-CoA biosynthetic process from pyruvate
0.52	GO:0055114	oxidation-reduction process
0.46	GO:0006101	citrate metabolic process
0.43	GO:0019362	pyridine nucleotide metabolic process
0.41	GO:0006091	generation of precursor metabolites and energy
0.41	GO:0006006	glucose metabolic process
0.37	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate

0.78	GO:0004738	pyruvate dehydrogenase activity
0.75	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
0.47	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0005515	protein binding

0.55	GO:0043231	intracellular membrane-bounded organelle
0.49	GO:0045254	pyruvate dehydrogenase complex
0.48	GO:0031974	membrane-enclosed lumen
0.47	GO:0043209	myelin sheath
0.43	GO:0044446	intracellular organelle part
0.43	GO:0043232	intracellular non-membrane-bounded organelle

0.75

EC:1.2.4

GO:0016624

sp|P35492|HUTH_MOUSE
Histidine ammonia-lyase
Search

HAL

0.58	Histidine ammonia-lyase

0.76	GO:0019557	histidine catabolic process to glutamate and formate
0.76	GO:0043606	formamide metabolic process
0.45	GO:0060218	hematopoietic stem cell differentiation

0.80

GO:0004397

histidine ammonia-lyase activity

0.48

GO:0005737

cytoplasm

0.80

EC:4.3.1.3

GO:0004397

sp|P35505|FAAA_MOUSE
Fumarylacetoacetase
Search

FAH

0.50	Fumarylacetoacetate hydrolase

0.69	GO:0009072	aromatic amino acid family metabolic process
0.50	GO:0006527	arginine catabolic process
0.39	GO:1902222	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process
0.37	GO:0042737	drug catabolic process
0.36	GO:1901361	organic cyclic compound catabolic process
0.36	GO:0019439	aromatic compound catabolic process
0.34	GO:0006396	RNA processing
0.33	GO:0090501	RNA phosphodiester bond hydrolysis
0.33	GO:0001510	RNA methylation
0.33	GO:0006399	tRNA metabolic process

0.83	GO:0004334	fumarylacetoacetase activity
0.34	GO:0046872	metal ion binding
0.34	GO:0016829	lyase activity
0.33	GO:0140098	catalytic activity, acting on RNA
0.33	GO:0005515	protein binding
0.33	GO:0030170	pyridoxal phosphate binding
0.33	GO:0004518	nuclease activity
0.33	GO:0008168	methyltransferase activity
0.32	GO:0003723	RNA binding
0.31	GO:0003677	DNA binding

0.36	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol

0.83	EC:3.7.1.2	GO:0004334
0.83	KEGG:R01364	GO:0004334

sp|P35545|UBIM_MOUSE
Ubiquitin-like protein FUBI
Search

FAU

0.97	Ubiquitin-like protein FUBI

0.80	GO:0002227	innate immune response in mucosa
0.78	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.77	GO:0019731	antibacterial humoral response
0.75	GO:0050830	defense response to Gram-positive bacterium

0.54	GO:0003723	RNA binding
0.50	GO:0003735	structural constituent of ribosome
0.49	GO:0005515	protein binding

0.72	GO:0022627	cytosolic small ribosomal subunit
0.66	GO:0005615	extracellular space

sp|P35546|RET_MOUSE
Proto-oncogene tyrosine-protein kinase receptor Ret
Search

RET

0.94	Proto-oncogene tyrosine-protein kinase receptor Ret

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.74	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.63	GO:0061146	Peyer's patch morphogenesis
0.63	GO:0048484	enteric nervous system development
0.62	GO:0035799	ureter maturation
0.62	GO:0072300	positive regulation of metanephric glomerulus development
0.62	GO:0001755	neural crest cell migration
0.61	GO:0007158	neuron cell-cell adhesion
0.61	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.60	GO:0033630	positive regulation of cell adhesion mediated by integrin

0.76	GO:0004713	protein tyrosine kinase activity
0.67	GO:0005509	calcium ion binding
0.67	GO:0019199	transmembrane receptor protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.38	GO:0005515	protein binding
0.38	GO:0003777	microtubule motor activity
0.37	GO:0008376	acetylgalactosaminyltransferase activity

0.68	GO:0098857	membrane microdomain
0.54	GO:0043235	receptor complex
0.54	GO:0010008	endosome membrane
0.50	GO:0005829	cytosol
0.49	GO:0005886	plasma membrane
0.46	GO:0098796	membrane protein complex
0.44	GO:0043231	intracellular membrane-bounded organelle
0.40	GO:0043025	neuronal cell body
0.40	GO:0030425	dendrite
0.40	GO:0005769	early endosome

0.76

GO:0004713

sp|P35550|FBRL_MOUSE
rRNA 2'-O-methyltransferase fibrillarin
Search

FBL

0.76	LOW QUALITY PROTEIN: rRNA 2'-O-methyltransferase fibrillarin

0.66	GO:0006364	rRNA processing
0.64	GO:0008033	tRNA processing
0.61	GO:0032259	methylation
0.55	GO:0016074	snoRNA metabolic process
0.54	GO:0048254	snoRNA localization
0.50	GO:0016570	histone modification
0.50	GO:0008213	protein alkylation
0.47	GO:0043628	ncRNA 3'-end processing
0.43	GO:0009451	RNA modification
0.38	GO:0001649	osteoblast differentiation

0.61	GO:0008168	methyltransferase activity
0.57	GO:0003723	RNA binding
0.53	GO:0001094	TFIID-class transcription factor binding
0.51	GO:0051117	ATPase binding
0.45	GO:0140102	catalytic activity, acting on a rRNA
0.43	GO:0140096	catalytic activity, acting on a protein

0.57	GO:0001650	fibrillar center
0.55	GO:0015030	Cajal body
0.53	GO:0001652	granular component
0.50	GO:0031428	box C/D snoRNP complex
0.48	GO:0032040	small-subunit processome
0.41	GO:0001651	dense fibrillar component
0.37	GO:0070062	extracellular exosome
0.36	GO:0005694	chromosome
0.30	GO:0016020	membrane

0.61

GO:0008168

sp|P35561|KCNJ2_MOUSE
Inward rectifier potassium channel 2
Search

KCNJ2

0.84	Inward rectifier potassium channel

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.62	GO:0014861	regulation of skeletal muscle contraction via regulation of action potential
0.62	GO:0090076	relaxation of skeletal muscle
0.61	GO:0098655	cation transmembrane transport
0.61	GO:0055119	relaxation of cardiac muscle
0.60	GO:0086013	membrane repolarization during cardiac muscle cell action potential
0.59	GO:0086002	cardiac muscle cell action potential involved in contraction
0.59	GO:0086091	regulation of heart rate by cardiac conduction
0.58	GO:0051289	protein homotetramerization

0.84	GO:0005242	inward rectifier potassium channel activity
0.60	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
0.57	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.51	GO:0042802	identical protein binding

0.54	GO:0008076	voltage-gated potassium channel complex
0.40	GO:0005790	smooth endoplasmic reticulum
0.39	GO:0030315	T-tubule
0.39	GO:0014704	intercalated disc
0.39	GO:0043197	dendritic spine
0.38	GO:0005791	rough endoplasmic reticulum
0.38	GO:0043025	neuronal cell body
0.37	GO:0005794	Golgi apparatus

sp|P35564|CALX_MOUSE
Calnexin
Search

CANX

0.86	LOW QUALITY PROTEIN: calnexin

0.69	GO:0006457	protein folding
0.56	GO:0048488	synaptic vesicle endocytosis
0.49	GO:0072583	clathrin-dependent endocytosis
0.42	GO:0048916	posterior lateral line development
0.39	GO:0007568	aging
0.36	GO:0070757	interleukin-35-mediated signaling pathway
0.36	GO:0070106	interleukin-27-mediated signaling pathway
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
0.34	GO:0007339	binding of sperm to zona pellucida

0.71	GO:0051082	unfolded protein binding
0.70	GO:0005509	calcium ion binding
0.40	GO:0034185	apolipoprotein binding
0.40	GO:0035255	ionotropic glutamate receptor binding
0.38	GO:0030246	carbohydrate binding
0.34	GO:0044183	protein binding involved in protein folding
0.34	GO:0003723	RNA binding
0.33	GO:0005198	structural molecule activity

0.70	GO:0005783	endoplasmic reticulum
0.54	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.54	GO:0044233	ER-mitochondrion membrane contact site
0.53	GO:0043209	myelin sheath
0.52	GO:0031984	organelle subcompartment
0.51	GO:0045202	synapse
0.40	GO:0042470	melanosome
0.40	GO:0032839	dendrite cytoplasm
0.39	GO:0044309	neuron spine
0.39	GO:0043025	neuronal cell body

sp|P35569|IRS1_MOUSE
Insulin receptor substrate 1
Search

IRS1

0.93	Insulin receptor substrate 1

0.85	GO:0048009	insulin-like growth factor receptor signaling pathway
0.85	GO:0032000	positive regulation of fatty acid beta-oxidation
0.85	GO:0045725	positive regulation of glycogen biosynthetic process
0.85	GO:2001275	positive regulation of glucose import in response to insulin stimulus
0.84	GO:0046676	negative regulation of insulin secretion
0.84	GO:0008286	insulin receptor signaling pathway
0.83	GO:0014065	phosphatidylinositol 3-kinase signaling
0.50	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
0.46	GO:0008284	positive regulation of cell proliferation
0.46	GO:0046628	positive regulation of insulin receptor signaling pathway

0.85	GO:0005158	insulin receptor binding
0.85	GO:0043548	phosphatidylinositol 3-kinase binding
0.85	GO:0005159	insulin-like growth factor receptor binding
0.81	GO:0001784	phosphotyrosine residue binding
0.53	GO:0042169	SH2 domain binding
0.52	GO:0004871	signal transducer activity
0.46	GO:0019901	protein kinase binding
0.44	GO:0035591	signaling adaptor activity
0.44	GO:0030674	protein binding, bridging
0.42	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity

0.79	GO:0005901	caveola
0.67	GO:0005829	cytosol
0.60	GO:0005634	nucleus
0.47	GO:0005899	insulin receptor complex
0.45	GO:0036064	ciliary basal body

0.42	EC:2.7.1.153	GO:0046934
0.42	KEGG:R04545	GO:0046934

sp|P35576|G6PC_MOUSE
Glucose-6-phosphatase
Search

G6PC

0.84	Acipenser baerii glucose-6-phosphatase mRNA

0.66	GO:0016311	dephosphorylation
0.64	GO:0006094	gluconeogenesis
0.57	GO:0015712	hexose phosphate transport
0.54	GO:0046415	urate metabolic process
0.54	GO:0035264	multicellular organism growth
0.54	GO:0042632	cholesterol homeostasis
0.54	GO:0042593	glucose homeostasis
0.52	GO:0006641	triglyceride metabolic process
0.52	GO:0005980	glycogen catabolic process
0.51	GO:0051156	glucose 6-phosphate metabolic process

0.85	GO:0004346	glucose-6-phosphatase activity
0.52	GO:0042301	phosphate ion binding
0.44	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.35	GO:0008131	primary amine oxidase activity
0.34	GO:0048038	quinone binding
0.34	GO:0005507	copper ion binding

0.62	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0008537	proteasome activator complex
0.30	GO:0016021	integral component of membrane

0.85	EC:3.1.3.9	GO:0004346
0.85	KEGG:R00303	GO:0004346

sp|P35582|FOXA1_MOUSE
Hepatocyte nuclear factor 3-alpha
Search

FOXA1

0.93	Hepatocyte nuclear factor 3-alpha

0.63	GO:1902691	respiratory basal cell differentiation
0.62	GO:0061144	alveolar secondary septum development
0.62	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.62	GO:0060741	prostate gland stromal morphogenesis
0.62	GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development
0.61	GO:0060743	epithelial cell maturation involved in prostate gland development
0.61	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
0.61	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
0.59	GO:0021904	dorsal/ventral neural tube patterning
0.59	GO:0060487	lung epithelial cell differentiation

0.76	GO:0019904	protein domain specific binding
0.72	GO:0008134	transcription factor binding
0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0044212	transcription regulatory region DNA binding
0.45	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.57	GO:0005902	microvillus
0.50	GO:0070013	intracellular organelle lumen
0.45	GO:0044446	intracellular organelle part
0.44	GO:0043232	intracellular non-membrane-bounded organelle
0.40	GO:0030054	cell junction

sp|P35583|FOXA2_MOUSE
Hepatocyte nuclear factor 3-beta
Search

FOXA2

0.95	Hepatocyte nuclear factor 3-alpha

0.62	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.59	GO:0071542	dopaminergic neuron differentiation
0.58	GO:0031018	endocrine pancreas development
0.57	GO:0051090	regulation of DNA binding transcription factor activity
0.57	GO:1900046	regulation of hemostasis
0.57	GO:0050818	regulation of coagulation
0.57	GO:0061041	regulation of wound healing
0.56	GO:0045893	positive regulation of transcription, DNA-templated
0.54	GO:0006357	regulation of transcription by RNA polymerase II
0.54	GO:0032101	regulation of response to external stimulus

0.76	GO:0019904	protein domain specific binding
0.72	GO:0008134	transcription factor binding
0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0044212	transcription regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.36	GO:0046332	SMAD binding
0.35	GO:0019900	kinase binding

0.61	GO:0005634	nucleus
0.52	GO:0030054	cell junction
0.50	GO:0070013	intracellular organelle lumen
0.45	GO:0044446	intracellular organelle part
0.43	GO:0005902	microvillus
0.38	GO:0005700	polytene chromosome
0.34	GO:0005737	cytoplasm

sp|P35584|FOXA3_MOUSE
Hepatocyte nuclear factor 3-gamma
Search

FOXA3

0.84	Forkhead box protein A2

0.69	GO:0042593	glucose homeostasis
0.66	GO:0045944	positive regulation of transcription by RNA polymerase II
0.64	GO:0007283	spermatogenesis
0.63	GO:0009267	cellular response to starvation
0.60	GO:0055082	cellular chemical homeostasis
0.56	GO:0009653	anatomical structure morphogenesis
0.55	GO:1902691	respiratory basal cell differentiation
0.55	GO:0021915	neural tube development
0.54	GO:0061144	alveolar secondary septum development
0.54	GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development

0.73	GO:0019904	protein domain specific binding
0.69	GO:0008134	transcription factor binding
0.66	GO:0044212	transcription regulatory region DNA binding
0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.36	GO:0003690	double-stranded DNA binding

0.62	GO:0005654	nucleoplasm
0.61	GO:0015629	actin cytoskeleton
0.50	GO:0005902	microvillus
0.50	GO:0001650	fibrillar center

sp|P35585|AP1M1_MOUSE
AP-1 complex subunit mu-1
Search

AP1M1

0.86	AP-1 complex subunit mu-1

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.57	GO:0035646	endosome to melanosome transport
0.56	GO:0032438	melanosome organization
0.43	GO:0048565	digestive tract development
0.42	GO:0048513	animal organ development
0.42	GO:0060322	head development
0.42	GO:0007417	central nervous system development
0.39	GO:2001136	negative regulation of endocytic recycling
0.39	GO:0033363	secretory granule organization

0.36	GO:0008565	protein transporter activity
0.34	GO:0005515	protein binding
0.33	GO:0003676	nucleic acid binding

0.79	GO:0030131	clathrin adaptor complex
0.41	GO:0030665	clathrin-coated vesicle membrane
0.39	GO:0035976	transcription factor AP-1 complex
0.39	GO:0005794	Golgi apparatus
0.38	GO:0030140	trans-Golgi network transport vesicle
0.37	GO:0030658	transport vesicle membrane
0.37	GO:0030120	vesicle coat
0.37	GO:0030660	Golgi-associated vesicle membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0035579	specific granule membrane

sp|P35601|RFC1_MOUSE
Replication factor C subunit 1
Search

RFC1

0.73	Replication factor C subunit 1

0.65	GO:0006260	DNA replication
0.64	GO:0006281	DNA repair
0.40	GO:0000122	negative regulation of transcription by RNA polymerase II
0.39	GO:0045893	positive regulation of transcription, DNA-templated
0.34	GO:0006351	transcription, DNA-templated

0.83	GO:0003689	DNA clamp loader activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0019904	protein domain specific binding
0.39	GO:0003690	double-stranded DNA binding
0.37	GO:0043565	sequence-specific DNA binding

0.82	GO:0005663	DNA replication factor C complex
0.55	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.39	GO:0070062	extracellular exosome
0.34	GO:0005737	cytoplasm

sp|P35639|DDIT3_MOUSE
DNA damage-inducible transcript 3 protein
Search

DDIT3

0.97	DNA damage-inducible transcript 3

0.79	GO:0007050	cell cycle arrest
0.79	GO:0006986	response to unfolded protein
0.78	GO:1990442	intrinsic apoptotic signaling pathway in response to nitrosative stress
0.77	GO:2000016	negative regulation of determination of dorsal identity
0.77	GO:0044324	regulation of transcription involved in anterior/posterior axis specification
0.76	GO:0032792	negative regulation of CREB transcription factor activity
0.75	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
0.74	GO:0001955	blood vessel maturation
0.74	GO:0006983	ER overload response
0.74	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

0.75	GO:0043522	leucine zipper domain binding
0.73	GO:0008140	cAMP response element binding protein binding
0.68	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.67	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.63	GO:0042803	protein homodimerization activity
0.62	GO:0046982	protein heterodimerization activity
0.53	GO:0003714	transcription corepressor activity

0.77	GO:0036488	CHOP-C/EBP complex
0.77	GO:1990617	CHOP-ATF4 complex
0.77	GO:1990622	CHOP-ATF3 complex
0.75	GO:0035976	transcription factor AP-1 complex
0.67	GO:0005770	late endosome
0.60	GO:0032993	protein-DNA complex
0.36	GO:0005654	nucleoplasm
0.36	GO:0005829	cytosol

sp|P35689|ERCC5_MOUSE
DNA repair protein complementing XP-G cells homolog
Search

ERCC5

0.90	Excision repair cross-complementing rodent repair deficiency, complementation group 5

0.73	GO:0006289	nucleotide-excision repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.51	GO:0010225	response to UV-C
0.48	GO:0009650	UV protection
0.47	GO:0043066	negative regulation of apoptotic process
0.46	GO:0035264	multicellular organism growth
0.46	GO:0008340	determination of adult lifespan

0.73	GO:0003697	single-stranded DNA binding
0.66	GO:0004519	endonuclease activity
0.51	GO:0000405	bubble DNA binding
0.49	GO:0004536	deoxyribonuclease activity
0.49	GO:0047485	protein N-terminus binding
0.46	GO:0042803	protein homodimerization activity
0.45	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.47	GO:1902554	serine/threonine protein kinase complex
0.46	GO:0000428	DNA-directed RNA polymerase complex
0.46	GO:0005667	transcription factor complex
0.43	GO:0030894	replisome
0.43	GO:0031974	membrane-enclosed lumen

sp|P35700|PRDX1_MOUSE
Peroxiredoxin-1
Search

PRDX1

0.84	Boundary element associated factor

0.69	GO:0098869	cellular oxidant detoxification
0.68	GO:0045454	cell redox homeostasis
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0030101	natural killer cell activation
0.52	GO:0042267	natural killer cell mediated cytotoxicity
0.51	GO:0042345	regulation of NF-kappaB import into nucleus
0.50	GO:0034101	erythrocyte homeostasis
0.49	GO:0032872	regulation of stress-activated MAPK cascade
0.49	GO:0042744	hydrogen peroxide catabolic process
0.49	GO:0008283	cell proliferation

0.73	GO:0051920	peroxiredoxin activity
0.50	GO:0045296	cadherin binding
0.48	GO:0004601	peroxidase activity
0.46	GO:0042802	identical protein binding
0.34	GO:0008430	selenium binding
0.34	GO:0003676	nucleic acid binding
0.33	GO:0046983	protein dimerization activity
0.33	GO:0020037	heme binding

0.50	GO:0043209	myelin sheath
0.43	GO:0005634	nucleus
0.42	GO:0005739	mitochondrion
0.36	GO:0031012	extracellular matrix
0.36	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.35	GO:0031907	microbody lumen
0.35	GO:0042470	melanosome
0.35	GO:0000791	euchromatin
0.34	GO:0044439	peroxisomal part

0.73	EC:1.11.1.15	GO:0051920
0.48	KEGG:R03532	GO:0004601

sp|P35710|SOX5_MOUSE
Transcription factor SOX-5
Search

SOX5

0.97	SRY-box-containing protein 5

0.77	GO:2000741	positive regulation of mesenchymal stem cell differentiation
0.74	GO:0032332	positive regulation of chondrocyte differentiation
0.74	GO:0055059	asymmetric neuroblast division
0.69	GO:0071560	cellular response to transforming growth factor beta stimulus

0.55

GO:0003677

DNA binding

0.61

GO:0005634

nucleus

sp|P35737|DMB_MOUSE
Class II histocompatibility antigen, M beta 1 chain
Search

0.39	Histocompatibility antigen DM heterodimer light chain

0.77	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
0.71	GO:0006955	immune response
0.54	GO:0002478	antigen processing and presentation of exogenous peptide antigen
0.52	GO:0051085	chaperone cofactor-dependent protein refolding
0.41	GO:2001190	positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
0.40	GO:0002399	MHC class II protein complex assembly
0.40	GO:0002501	peptide antigen assembly with MHC protein complex
0.39	GO:0042102	positive regulation of T cell proliferation
0.33	GO:0006629	lipid metabolic process
0.33	GO:0035556	intracellular signal transduction

0.56	GO:0023026	MHC class II protein complex binding
0.35	GO:0004435	phosphatidylinositol phospholipase C activity

0.73	GO:0042613	MHC class II protein complex
0.52	GO:0005771	multivesicular body
0.51	GO:0005765	lysosomal membrane
0.50	GO:0010008	endosome membrane
0.34	GO:0005581	collagen trimer
0.30	GO:0016021	integral component of membrane

0.35	EC:3.1.4.11	GO:0004435
0.35	KEGG:R03435	GO:0004435

sp|P35761|TTK_MOUSE
Dual specificity protein kinase TTK
Search

TTK

0.92	Dual specificity protein kinase TTK

0.80	GO:0007093	mitotic cell cycle checkpoint
0.79	GO:0051304	chromosome separation
0.64	GO:1903096	protein localization to meiotic spindle midzone
0.63	GO:0006468	protein phosphorylation
0.61	GO:0016321	female meiosis chromosome segregation
0.61	GO:0044779	meiotic spindle checkpoint
0.59	GO:0034501	protein localization to kinetochore
0.58	GO:0018210	peptidyl-threonine modification
0.57	GO:0071173	spindle assembly checkpoint
0.57	GO:0018209	peptidyl-serine modification

0.81	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0042803	protein homodimerization activity
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0004674	protein serine/threonine kinase activity
0.39	GO:0004713	protein tyrosine kinase activity
0.38	GO:0043515	kinetochore binding

0.55	GO:0000776	kinetochore
0.40	GO:0005737	cytoplasm
0.35	GO:0005819	spindle
0.30	GO:0016021	integral component of membrane

0.81

EC:2.7.12.1

GO:0004712

sp|P35762|CD81_MOUSE
CD81 antigen
Search

CD81

0.59	Tetraspanin

0.58	GO:0043126	regulation of 1-phosphatidylinositol 4-kinase activity
0.55	GO:1904352	positive regulation of protein catabolic process in the vacuole
0.55	GO:0090218	positive regulation of lipid kinase activity
0.54	GO:0071404	cellular response to low-density lipoprotein particle stimulus
0.54	GO:1903727	positive regulation of phospholipid metabolic process
0.53	GO:0061462	protein localization to lysosome
0.53	GO:0030890	positive regulation of B cell proliferation
0.53	GO:0000187	activation of MAPK activity
0.53	GO:0031623	receptor internalization
0.53	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation

0.54	GO:1990459	transferrin receptor binding
0.54	GO:0104005	hijacked molecular function

0.53	GO:0001772	immunological synapse
0.51	GO:0016323	basolateral plasma membrane
0.51	GO:0070062	extracellular exosome
0.47	GO:0005887	integral component of plasma membrane

sp|P35802|GPM6A_MOUSE
Neuronal membrane glycoprotein M6-a
Search

GPM6A

0.94	Proteolipid protein DM beta

0.54	GO:0001764	neuron migration
0.53	GO:0048863	stem cell differentiation
0.53	GO:0003407	neural retina development
0.52	GO:0031175	neuron projection development
0.50	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.46	GO:0051489	regulation of filopodium assembly
0.41	GO:0120034	positive regulation of plasma membrane bounded cell projection assembly
0.41	GO:0007416	synapse assembly
0.38	GO:0070588	calcium ion transmembrane transport

0.38	GO:0005262	calcium channel activity
0.34	GO:0005515	protein binding

0.54	GO:0044295	axonal growth cone
0.41	GO:0030175	filopodium
0.40	GO:0043025	neuronal cell body
0.40	GO:0043197	dendritic spine
0.36	GO:0070062	extracellular exosome
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P35803|GPM6B_MOUSE
Neuronal membrane glycoprotein M6-b
Search

GPM6B

0.95	Neuronal membrane glycoprotein M6-b

0.54	GO:0030501	positive regulation of bone mineralization
0.54	GO:0051893	regulation of focal adhesion assembly
0.54	GO:0085029	extracellular matrix assembly
0.50	GO:0032956	regulation of actin cytoskeleton organization
0.40	GO:0051612	negative regulation of serotonin uptake
0.39	GO:2000009	negative regulation of protein localization to cell surface
0.38	GO:0001503	ossification
0.36	GO:0007399	nervous system development
0.35	GO:0015031	protein transport
0.35	GO:0030154	cell differentiation

0.38	GO:0045121	membrane raft
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P35821|PTN1_MOUSE
Tyrosine-protein phosphatase non-receptor type 1
Search

PTPN1

0.75	Tyrosine-protein phosphatase non-receptor type

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.58	GO:1903898	negative regulation of PERK-mediated unfolded protein response
0.57	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway
0.57	GO:0035791	platelet-derived growth factor receptor-beta signaling pathway
0.57	GO:2000646	positive regulation of receptor catabolic process
0.57	GO:0036498	IRE1-mediated unfolded protein response
0.56	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.56	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway
0.55	GO:0007257	activation of JUN kinase activity
0.54	GO:0008286	insulin receptor signaling pathway

0.75	GO:0004725	protein tyrosine phosphatase activity
0.54	GO:0046875	ephrin receptor binding
0.54	GO:0030971	receptor tyrosine kinase binding
0.52	GO:0045296	cadherin binding
0.44	GO:0008270	zinc ion binding
0.41	GO:0005158	insulin receptor binding
0.41	GO:0051721	protein phosphatase 2A binding
0.34	GO:0003723	RNA binding

0.57	GO:0097443	sorting endosome
0.55	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane
0.52	GO:0005769	early endosome
0.41	GO:0005886	plasma membrane
0.38	GO:0005829	cytosol
0.35	GO:0031225	anchored component of membrane
0.30	GO:0016021	integral component of membrane

0.75

GO:0004725

sp|P35822|PTPRK_MOUSE
Receptor-type tyrosine-protein phosphatase kappa
Search

PTPRK

0.86	Mutant receptor type protein tyrosine phosphatase K

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.65	GO:0010839	negative regulation of keratinocyte proliferation
0.65	GO:0048041	focal adhesion assembly
0.64	GO:0034394	protein localization to cell surface
0.61	GO:0034644	cellular response to UV
0.61	GO:0007179	transforming growth factor beta receptor signaling pathway
0.60	GO:0030336	negative regulation of cell migration
0.57	GO:0016477	cell migration
0.57	GO:0045786	negative regulation of cell cycle
0.56	GO:0034614	cellular response to reactive oxygen species

0.74	GO:0004725	protein tyrosine phosphatase activity
0.65	GO:0045295	gamma-catenin binding
0.61	GO:0008013	beta-catenin binding
0.58	GO:0019901	protein kinase binding

0.62	GO:0001750	photoreceptor outer segment
0.61	GO:0031256	leading edge membrane
0.59	GO:0043025	neuronal cell body
0.59	GO:0030425	dendrite
0.59	GO:0030424	axon
0.57	GO:0005911	cell-cell junction
0.56	GO:0009986	cell surface
0.45	GO:0043227	membrane-bounded organelle
0.43	GO:0043229	intracellular organelle
0.30	GO:0016021	integral component of membrane

0.74

GO:0004725

sp|P35831|PTN12_MOUSE
Tyrosine-protein phosphatase non-receptor type 12
Search

PTPN12

0.66	Tyrosine-protein phosphatase

0.73	GO:0035335	peptidyl-tyrosine dephosphorylation
0.63	GO:0071364	cellular response to epidermal growth factor stimulus
0.61	GO:0042058	regulation of epidermal growth factor receptor signaling pathway
0.41	GO:0042246	tissue regeneration
0.37	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway
0.37	GO:0038128	ERBB2 signaling pathway
0.36	GO:1901185	negative regulation of ERBB signaling pathway
0.35	GO:0071345	cellular response to cytokine stimulus

0.73	GO:0004725	protein tyrosine phosphatase activity
0.58	GO:0017124	SH3 domain binding

0.62	GO:0002102	podosome
0.52	GO:0005829	cytosol
0.38	GO:0005925	focal adhesion
0.36	GO:0042995	cell projection
0.34	GO:0005654	nucleoplasm

0.73

GO:0004725

sp|P35846|FOLR1_MOUSE
Folate receptor alpha
Search

0.70	Folate receptor alpha

0.85	GO:0015884	folic acid transport
0.59	GO:0071231	cellular response to folic acid
0.53	GO:0061713	anterior neural tube closure
0.52	GO:0003147	neural crest cell migration involved in heart formation
0.51	GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis
0.51	GO:0061626	pharyngeal arch artery morphogenesis
0.50	GO:0031103	axon regeneration
0.49	GO:0001947	heart looping
0.48	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
0.47	GO:0060828	regulation of canonical Wnt signaling pathway

0.85	GO:0008517	folic acid transmembrane transporter activity
0.84	GO:0005542	folic acid binding
0.59	GO:0061714	folic acid receptor activity
0.58	GO:0051870	methotrexate binding
0.34	GO:0005344	oxygen carrier activity
0.34	GO:0019825	oxygen binding
0.34	GO:0046914	transition metal ion binding
0.33	GO:0020037	heme binding

0.55	GO:0031362	anchored component of external side of plasma membrane
0.48	GO:0016324	apical plasma membrane
0.48	GO:0016323	basolateral plasma membrane
0.41	GO:0031526	brush border membrane
0.41	GO:0005634	nucleus
0.39	GO:0031982	vesicle
0.38	GO:0005576	extracellular region
0.36	GO:0012505	endomembrane system
0.35	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.34	GO:0005833	hemoglobin complex

sp|P35917|VGFR3_MOUSE
Vascular endothelial growth factor receptor 3
Search

FLT4

0.93	Fms related tyrosine kinase 4

0.85	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.85	GO:0038084	vascular endothelial growth factor signaling pathway
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.66	GO:0001946	lymphangiogenesis
0.66	GO:0090037	positive regulation of protein kinase C signaling
0.65	GO:0010575	positive regulation of vascular endothelial growth factor production
0.63	GO:0001938	positive regulation of endothelial cell proliferation
0.63	GO:0060312	regulation of blood vessel remodeling
0.63	GO:0010595	positive regulation of endothelial cell migration
0.62	GO:0046330	positive regulation of JNK cascade

0.85	GO:0005021	vascular endothelial growth factor-activated receptor activity
0.62	GO:0019903	protein phosphatase binding
0.61	GO:0019838	growth factor binding
0.57	GO:0042803	protein homodimerization activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0036332	placental growth factor-activated receptor activity

0.67	GO:0005887	integral component of plasma membrane
0.59	GO:0043235	receptor complex
0.54	GO:0005654	nucleoplasm
0.34	GO:0015629	actin cytoskeleton

sp|P35918|VGFR2_MOUSE
Vascular endothelial growth factor receptor 2
Search

KDR

0.58	Vascular endothelial growth factor receptor

0.84	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.84	GO:0038084	vascular endothelial growth factor signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.65	GO:1904881	cellular response to hydrogen sulfide
0.63	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process
0.63	GO:0051901	positive regulation of mitochondrial depolarization
0.63	GO:2001028	positive regulation of endothelial cell chemotaxis
0.62	GO:0090141	positive regulation of mitochondrial fission
0.62	GO:0050927	positive regulation of positive chemotaxis
0.62	GO:0051894	positive regulation of focal adhesion assembly

0.85	GO:0005021	vascular endothelial growth factor-activated receptor activity
0.80	GO:0019838	growth factor binding
0.59	GO:0005178	integrin binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.54	GO:0042802	identical protein binding
0.36	GO:0051879	Hsp90 protein binding
0.36	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity

0.57	GO:0098857	membrane microdomain
0.55	GO:0005768	endosome
0.52	GO:0005794	Golgi apparatus
0.52	GO:0005783	endoplasmic reticulum
0.51	GO:0005887	integral component of plasma membrane
0.39	GO:0030054	cell junction
0.38	GO:0009897	external side of plasma membrane
0.36	GO:0005634	nucleus
0.35	GO:0043025	neuronal cell body
0.35	GO:0005576	extracellular region

0.36

GO:0004716

sp|P35922|FMR1_MOUSE
Synaptic functional regulator FMR1
Search

FMR1

0.95	Fragile X mental retardation 1

0.66	GO:1901254	positive regulation of intracellular transport of viral material
0.65	GO:0044830	modulation by host of viral RNA genome replication
0.64	GO:0098908	regulation of neuronal action potential
0.64	GO:0033129	positive regulation of histone phosphorylation
0.64	GO:1902416	positive regulation of mRNA binding
0.62	GO:2000637	positive regulation of gene silencing by miRNA
0.62	GO:0002092	positive regulation of receptor internalization
0.61	GO:0060998	regulation of dendritic spine development
0.61	GO:1902373	negative regulation of mRNA catabolic process
0.61	GO:0051489	regulation of filopodium assembly

0.63	GO:0034046	poly(G) binding
0.63	GO:1990825	sequence-specific mRNA binding
0.62	GO:0035613	RNA stem-loop binding
0.62	GO:0035197	siRNA binding
0.62	GO:0035198	miRNA binding
0.62	GO:0002151	G-quadruplex RNA binding
0.61	GO:0030371	translation repressor activity
0.61	GO:0008266	poly(U) RNA binding
0.60	GO:0033592	RNA strand annealing activity
0.60	GO:0044325	ion channel binding

0.65	GO:0019034	viral replication complex
0.63	GO:1990124	messenger ribonucleoprotein complex
0.61	GO:0032797	SMN complex
0.61	GO:0043204	perikaryon
0.60	GO:0030426	growth cone
0.59	GO:0005844	polysome
0.57	GO:0048471	perinuclear region of cytoplasm
0.57	GO:0036464	cytoplasmic ribonucleoprotein granule
0.54	GO:0005730	nucleolus
0.52	GO:0005654	nucleoplasm

sp|P35951|LDLR_MOUSE
Low-density lipoprotein receptor
Search

LDLR

0.85	Low density lipoprotein receptor a

0.55	GO:0090118	receptor-mediated endocytosis involved in cholesterol transport
0.52	GO:0061889	negative regulation of astrocyte activation
0.52	GO:0061771	response to caloric restriction
0.51	GO:1903979	negative regulation of microglial cell activation
0.51	GO:0030299	intestinal cholesterol absorption
0.51	GO:0070508	cholesterol import
0.51	GO:1905167	positive regulation of lysosomal protein catabolic process
0.51	GO:0010899	regulation of phosphatidylcholine catabolic process
0.51	GO:0034383	low-density lipoprotein particle clearance
0.51	GO:1905907	negative regulation of amyloid fibril formation

0.70	GO:0005509	calcium ion binding
0.54	GO:0005041	low-density lipoprotein receptor activity
0.51	GO:0030229	very-low-density lipoprotein particle receptor activity
0.51	GO:0030169	low-density lipoprotein particle binding
0.48	GO:0001540	amyloid-beta binding
0.48	GO:0002020	protease binding
0.45	GO:0042802	identical protein binding
0.33	GO:0032050	clathrin heavy chain binding
0.33	GO:0104005	hijacked molecular function
0.33	GO:0004930	G-protein coupled receptor activity

0.52	GO:1990666	PCSK9-LDLR complex
0.50	GO:0097443	sorting endosome
0.50	GO:0005905	clathrin-coated pit
0.49	GO:0005770	late endosome
0.49	GO:0005769	early endosome
0.49	GO:0005764	lysosome
0.47	GO:0009897	external side of plasma membrane
0.47	GO:0016323	basolateral plasma membrane
0.47	GO:0034362	low-density lipoprotein particle
0.47	GO:0043235	receptor complex

sp|P35969|VGFR1_MOUSE
Vascular endothelial growth factor receptor 1
Search

FLT1

0.58	Kinase insert domain receptor like

0.82	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.82	GO:0038084	vascular endothelial growth factor signaling pathway
0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.65	GO:1905563	negative regulation of vascular endothelial cell proliferation
0.64	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
0.63	GO:0010863	positive regulation of phospholipase C activity
0.63	GO:0002548	monocyte chemotaxis
0.63	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
0.61	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.60	GO:0045766	positive regulation of angiogenesis

0.82	GO:0005021	vascular endothelial growth factor-activated receptor activity
0.67	GO:0036332	placental growth factor-activated receptor activity
0.61	GO:0019838	growth factor binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0042802	identical protein binding
0.38	GO:0019903	protein phosphatase binding
0.37	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity

0.63	GO:0005887	integral component of plasma membrane
0.58	GO:0043235	receptor complex
0.54	GO:0015629	actin cytoskeleton
0.38	GO:0005768	endosome
0.38	GO:0005925	focal adhesion
0.37	GO:0005615	extracellular space
0.36	GO:0005634	nucleus
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part

0.37

GO:0004716

sp|P35979|RL12_MOUSE
60S ribosomal protein L12
Search

RPL12

0.71	Alpha-tubulin N-acetyltransferase 1 (Fragment)

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.50	GO:0000027	ribosomal large subunit assembly
0.34	GO:0045901	positive regulation of translational elongation
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.45	GO:0019843	rRNA binding
0.34	GO:0005515	protein binding
0.32	GO:0016740	transferase activity

0.61	GO:0005840	ribosome
0.47	GO:0044445	cytosolic part
0.42	GO:0044446	intracellular organelle part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016740

sp|P35980|RL18_MOUSE
60S ribosomal protein L18
Search

RPL18

0.73	Ribosomal protein L18

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0097421	liver regeneration
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis

0.64	GO:0003735	structural constituent of ribosome
0.39	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.47	GO:0005844	polysome
0.47	GO:0044445	cytosolic part
0.44	GO:0005730	nucleolus
0.43	GO:0005783	endoplasmic reticulum
0.36	GO:0005925	focal adhesion
0.30	GO:0031224	intrinsic component of membrane

sp|P35991|BTK_MOUSE
Tyrosine-protein kinase BTK
Search

BTK

0.60	Tyrosine-protein kinase

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.61	GO:0002344	B cell affinity maturation
0.61	GO:0098761	cellular response to interleukin-7
0.61	GO:0035556	intracellular signal transduction
0.58	GO:0030889	negative regulation of B cell proliferation
0.55	GO:0001818	negative regulation of cytokine production
0.55	GO:0048469	cell maturation
0.48	GO:0046777	protein autophosphorylation
0.46	GO:0045087	innate immune response
0.46	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

0.80	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.59	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0042802	identical protein binding
0.44	GO:0005102	receptor binding
0.34	GO:0046872	metal ion binding

0.56	GO:0045121	membrane raft
0.50	GO:0031410	cytoplasmic vesicle
0.50	GO:0005829	cytosol
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.45	GO:0005634	nucleus
0.40	GO:0042629	mast cell granule
0.38	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005739	mitochondrion

0.80

GO:0004715

sp|P36363|FGF7_MOUSE
Fibroblast growth factor 7
Search

FGF7

0.63	Fibroblast growth factor

0.84	GO:0008543	fibroblast growth factor receptor signaling pathway
0.75	GO:0010469	regulation of receptor activity
0.66	GO:0061033	secretion by lung epithelial cell involved in lung growth
0.65	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis
0.64	GO:0051549	positive regulation of keratinocyte migration
0.64	GO:0010838	positive regulation of keratinocyte proliferation
0.64	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
0.63	GO:0010463	mesenchymal cell proliferation
0.63	GO:0034394	protein localization to cell surface
0.62	GO:0060445	branching involved in salivary gland morphogenesis

0.85	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.63	GO:0042056	chemoattractant activity
0.45	GO:0008201	heparin binding
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0004713	protein tyrosine kinase activity
0.34	GO:0004335	galactokinase activity
0.34	GO:0005534	galactose binding

0.66	GO:0005576	extracellular region
0.52	GO:0005794	Golgi apparatus
0.33	GO:0009986	cell surface
0.32	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|P36368|EGFB2_MOUSE
Epidermal growth factor-binding protein type B
Search

0.97	Epidermal growth factor-binding protein type B

0.61	GO:0006508	proteolysis
0.40	GO:0002675	positive regulation of acute inflammatory response
0.39	GO:0051604	protein maturation
0.39	GO:0007584	response to nutrient
0.39	GO:0008284	positive regulation of cell proliferation
0.38	GO:0043065	positive regulation of apoptotic process
0.38	GO:0008015	blood circulation
0.37	GO:0002936	bradykinin biosynthetic process
0.37	GO:0002255	tissue kallikrein-kinin cascade
0.37	GO:0035296	regulation of tube diameter

0.69	GO:0004252	serine-type endopeptidase activity
0.43	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.38	GO:0005057	signal transducer activity, downstream of receptor
0.36	GO:0008083	growth factor activity
0.34	GO:0046872	metal ion binding
0.33	GO:0090729	toxin activity
0.33	GO:0019899	enzyme binding

0.48	GO:0005615	extracellular space
0.41	GO:0030141	secretory granule
0.41	GO:1903561	extracellular vesicle
0.40	GO:0005634	nucleus
0.40	GO:0043234	protein complex
0.39	GO:0097223	sperm part
0.39	GO:0045177	apical part of cell
0.34	GO:0005766	primary lysosome
0.34	GO:0060205	cytoplasmic vesicle lumen
0.34	GO:0005775	vacuolar lumen

0.69

GO:0004252

sp|P36369|K1B26_MOUSE
Kallikrein 1-related peptidase b26
Search

0.97	Epidermal growth factor-binding protein type B

0.61	GO:0006508	proteolysis
0.40	GO:0002675	positive regulation of acute inflammatory response
0.39	GO:0051604	protein maturation
0.39	GO:0007584	response to nutrient
0.39	GO:0008284	positive regulation of cell proliferation
0.39	GO:0043065	positive regulation of apoptotic process
0.38	GO:0008015	blood circulation
0.37	GO:0002936	bradykinin biosynthetic process
0.37	GO:0002255	tissue kallikrein-kinin cascade
0.37	GO:0035296	regulation of tube diameter

0.69	GO:0004252	serine-type endopeptidase activity
0.44	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.38	GO:0005057	signal transducer activity, downstream of receptor
0.36	GO:0008083	growth factor activity
0.35	GO:0090729	toxin activity
0.35	GO:0046872	metal ion binding
0.33	GO:0019899	enzyme binding

0.49	GO:0005615	extracellular space
0.41	GO:1903561	extracellular vesicle
0.41	GO:0030141	secretory granule
0.40	GO:0043234	protein complex
0.40	GO:0005634	nucleus
0.39	GO:0097223	sperm part
0.39	GO:0045177	apical part of cell
0.34	GO:0005766	primary lysosome
0.34	GO:0060205	cytoplasmic vesicle lumen
0.34	GO:0005775	vacuolar lumen

0.69

GO:0004252

sp|P36371|TAP2_MOUSE
Antigen peptide transporter 2
Search

TAP2

0.31	Major histocompatibility complex class I

0.85	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
0.64	GO:0042886	amide transport
0.61	GO:0071702	organic substance transport
0.55	GO:0055085	transmembrane transport
0.52	GO:0002489	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent
0.51	GO:0002481	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
0.49	GO:0001916	positive regulation of T cell mediated cytotoxicity
0.47	GO:0046967	cytosol to ER transport
0.46	GO:0002237	response to molecule of bacterial origin
0.43	GO:0006955	immune response

0.85	GO:0042287	MHC protein binding
0.85	GO:0015440	peptide-transporting ATPase activity
0.63	GO:0046977	TAP binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0046980	tapasin binding
0.37	GO:0042605	peptide antigen binding
0.36	GO:0042803	protein homodimerization activity
0.35	GO:0046982	protein heterodimerization activity

0.86	GO:0042825	TAP complex
0.41	GO:0016607	nuclear speck
0.40	GO:0042613	MHC class II protein complex
0.40	GO:0005815	microtubule organizing center
0.37	GO:0005739	mitochondrion
0.37	GO:0030670	phagocytic vesicle membrane
0.36	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.34	GO:0005839	proteasome core complex
0.33	GO:0005887	integral component of plasma membrane

0.85

EC:3.6.3.43

GO:0015440

sp|P36423|THAS_MOUSE
Thromboxane-A synthase
Search

TBXAS1

0.96	Thromboxane-A synthase

0.53	GO:0055114	oxidation-reduction process
0.44	GO:0046457	prostanoid biosynthetic process
0.44	GO:0006693	prostaglandin metabolic process
0.40	GO:0030644	cellular chloride ion homeostasis
0.39	GO:0045907	positive regulation of vasoconstriction
0.39	GO:0070542	response to fatty acid
0.39	GO:0045471	response to ethanol
0.36	GO:0019369	arachidonic acid metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.65	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.62	GO:0004796	thromboxane-A synthase activity
0.37	GO:0036134	12-hydroxyheptadecatrienoic acid synthase activity

0.40	GO:0005789	endoplasmic reticulum membrane
0.32	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.68	EC:1.14	GO:0016705
0.62	KEGG:R02268	GO:0004796

sp|P36536|SAR1A_MOUSE
GTP-binding protein SAR1a
Search

SAR1A

0.84	Secretion associated Ras related GTPase 1A

0.69	GO:0090110	cargo loading into COPII-coated vesicle
0.69	GO:0006886	intracellular protein transport
0.49	GO:0030299	intestinal cholesterol absorption
0.47	GO:0048703	embryonic viscerocranium morphogenesis
0.47	GO:0035265	organ growth
0.44	GO:0007417	central nervous system development

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.71	GO:0005794	Golgi apparatus
0.70	GO:0005783	endoplasmic reticulum
0.63	GO:0030127	COPII vesicle coat
0.55	GO:0031984	organelle subcompartment

sp|P36552|HEM6_MOUSE
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial
Search

CPOX

0.45	Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial

0.71	GO:0006779	porphyrin-containing compound biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0042168	heme metabolic process
0.48	GO:0046148	pigment biosynthetic process
0.46	GO:0042541	hemoglobin biosynthetic process
0.40	GO:0010288	response to lead ion
0.40	GO:0051597	response to methylmercury
0.40	GO:0017085	response to insecticide
0.39	GO:0010039	response to iron ion
0.38	GO:0046685	response to arsenic-containing substance

0.78	GO:0004109	coproporphyrinogen oxidase activity
0.55	GO:0005212	structural constituent of eye lens
0.51	GO:0042803	protein homodimerization activity
0.36	GO:0005391	sodium:potassium-exchanging ATPase activity
0.34	GO:0003723	RNA binding

0.48	GO:0005829	cytosol
0.44	GO:0005739	mitochondrion
0.38	GO:0031970	organelle envelope lumen
0.35	GO:0019866	organelle inner membrane
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.78	EC:1.3.3.3	GO:0004109
0.78	KEGG:R03220	GO:0004109

sp|P36895|BMR1A_MOUSE
Bone morphogenetic protein receptor type-1A
Search

BMPR1A

0.61	Receptor protein serine/threonine kinase

0.80	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.66	GO:0023014	signal transduction by protein phosphorylation
0.60	GO:0002062	chondrocyte differentiation
0.59	GO:0021998	neural plate mediolateral regionalization
0.59	GO:1905285	fibrous ring of heart morphogenesis
0.59	GO:0048352	paraxial mesoderm structural organization
0.59	GO:1904414	positive regulation of cardiac ventricle development
0.59	GO:0071773	cellular response to BMP stimulus
0.58	GO:0001880	Mullerian duct regression
0.58	GO:0048378	regulation of lateral mesodermal cell fate specification

0.83	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.80	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.55	GO:0046332	SMAD binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.39	GO:0046872	metal ion binding

0.54	GO:0005901	caveola
0.53	GO:0009897	external side of plasma membrane
0.46	GO:0043235	receptor complex
0.39	GO:0005887	integral component of plasma membrane
0.38	GO:0043025	neuronal cell body
0.38	GO:0030425	dendrite
0.37	GO:0089717	spanning component of membrane

0.83

GO:0004675

sp|P36898|BMR1B_MOUSE
Bone morphogenetic protein receptor type-1B
Search

BMPR1B

0.60	Receptor protein serine/threonine kinase

0.80	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.72	GO:1902731	negative regulation of chondrocyte proliferation
0.70	GO:0002063	chondrocyte development
0.69	GO:0061036	positive regulation of cartilage development
0.68	GO:0060350	endochondral bone morphogenesis
0.67	GO:0030166	proteoglycan biosynthetic process
0.66	GO:0023014	signal transduction by protein phosphorylation
0.56	GO:0071773	cellular response to BMP stimulus
0.55	GO:0030501	positive regulation of bone mineralization
0.55	GO:0045669	positive regulation of osteoblast differentiation

0.83	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.80	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0046332	SMAD binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0046872	metal ion binding

0.41	GO:0005886	plasma membrane
0.38	GO:0043235	receptor complex
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.35	GO:0089717	spanning component of membrane

0.83

GO:0004675

sp|P36916|GNL1_MOUSE
Guanine nucleotide-binding protein-like 1
Search

GNL1

0.91	G protein nucleolar 1 (putative)

0.57	GO:0006974	cellular response to DNA damage stimulus
0.49	GO:0042254	ribosome biogenesis

0.66	GO:0001883	purine nucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.65	GO:0032549	ribonucleoside binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0003924	GTPase activity

sp|P36993|PPM1B_MOUSE
Protein phosphatase 1B
Search

sp|P37040|NCPR_MOUSE
NADPH--cytochrome P450 reductase
Search

POR

0.66	NADPH--cytochrome P450 reductase

0.55	GO:0090345	cellular organohalogen metabolic process
0.53	GO:0032770	positive regulation of monooxygenase activity
0.52	GO:0055114	oxidation-reduction process
0.40	GO:0043602	nitrate catabolic process
0.40	GO:0003420	regulation of growth plate cartilage chondrocyte proliferation
0.40	GO:0046210	nitric oxide catabolic process
0.39	GO:0045542	positive regulation of cholesterol biosynthetic process
0.39	GO:0090031	positive regulation of steroid hormone biosynthetic process
0.39	GO:0071372	cellular response to follicle-stimulating hormone stimulus
0.39	GO:0060192	negative regulation of lipase activity

0.81	GO:0003958	NADPH-hemoprotein reductase activity
0.69	GO:0010181	FMN binding
0.64	GO:0050661	NADP binding
0.61	GO:0050660	flavin adenine dinucleotide binding
0.40	GO:0047726	iron-cytochrome-c reductase activity
0.38	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H
0.38	GO:0008941	nitric oxide dioxygenase activity
0.36	GO:0019899	enzyme binding
0.35	GO:0009055	electron transfer activity
0.34	GO:0016787	hydrolase activity

0.67	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.81

EC:1.6.2.4

GO:0003958

sp|P37172|ACVR1_MOUSE
Activin receptor type-1
Search

ACVR1

0.61	Serine/threonine-protein kinase receptor

0.80	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.66	GO:0023014	signal transduction by protein phosphorylation
0.62	GO:0061445	endocardial cushion cell fate commitment
0.61	GO:0003289	atrial septum primum morphogenesis
0.61	GO:2000017	positive regulation of determination of dorsal identity
0.61	GO:0003274	endocardial cushion fusion
0.60	GO:0060923	cardiac muscle cell fate commitment
0.60	GO:1905007	positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
0.60	GO:0003183	mitral valve morphogenesis
0.59	GO:0032926	negative regulation of activin receptor signaling pathway

0.82	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.79	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.60	GO:0048185	activin binding
0.60	GO:0050431	transforming growth factor beta binding
0.57	GO:0046332	SMAD binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.52	GO:0042803	protein homodimerization activity

0.60	GO:0048179	activin receptor complex
0.54	GO:0045177	apical part of cell
0.39	GO:0070724	BMP receptor complex
0.37	GO:0005938	cell cortex

0.82

GO:0004675

sp|P37217|CD69_MOUSE
Early activation antigen CD69
Search

CD69

0.97	Type II membrane protein CD69 splice variant

0.69	GO:0035690	cellular response to drug
0.44	GO:0001867	complement activation, lectin pathway
0.35	GO:0007165	signal transduction

0.69	GO:0030246	carbohydrate binding
0.65	GO:0042803	protein homodimerization activity
0.43	GO:0005509	calcium ion binding
0.36	GO:0099600	transmembrane receptor activity
0.36	GO:0038023	signaling receptor activity

0.70	GO:0009897	external side of plasma membrane
0.53	GO:0043234	protein complex
0.36	GO:0005887	integral component of plasma membrane

sp|P37237|FGF8_MOUSE
Fibroblast growth factor 8
Search

FGF8

0.62	Fibroblast growth factor

0.82	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.57	GO:0030917	midbrain-hindbrain boundary development
0.57	GO:0030916	otic vesicle formation
0.56	GO:0090133	mesendoderm migration
0.56	GO:0030878	thyroid gland development
0.56	GO:0060037	pharyngeal system development
0.56	GO:0060128	corticotropin hormone secreting cell differentiation
0.55	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation
0.55	GO:0021798	forebrain dorsal/ventral pattern formation

0.83	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.37	GO:0042056	chemoattractant activity
0.35	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0004713	protein tyrosine kinase activity

0.65	GO:0005576	extracellular region
0.39	GO:0005764	lysosome
0.36	GO:0009897	external side of plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

sp|P37238|PPARG_MOUSE
Peroxisome proliferator-activated receptor gamma
Search

PPARG

0.93	Peroxisome proliferator-activated receptor gamma

0.80	GO:0048511	rhythmic process
0.79	GO:0030522	intracellular receptor signaling pathway
0.77	GO:0043401	steroid hormone mediated signaling pathway
0.60	GO:0010742	macrophage derived foam cell differentiation
0.60	GO:0045713	low-density lipoprotein particle receptor biosynthetic process
0.59	GO:1905563	negative regulation of vascular endothelial cell proliferation
0.59	GO:1905461	positive regulation of vascular associated smooth muscle cell apoptotic process
0.59	GO:0010887	negative regulation of cholesterol storage
0.59	GO:0060331	negative regulation of response to interferon-gamma
0.59	GO:0010871	negative regulation of receptor biosynthetic process

0.82	GO:0004879	nuclear receptor activity
0.78	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.59	GO:0050692	DBD domain binding
0.59	GO:0050693	LBD domain binding
0.58	GO:0046965	retinoid X receptor binding
0.57	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.57	GO:0051393	alpha-actinin binding
0.56	GO:0043621	protein self-association

0.61	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.48	GO:0005737	cytoplasm
0.43	GO:0044446	intracellular organelle part
0.35	GO:0070013	intracellular organelle lumen
0.30	GO:0016021	integral component of membrane

sp|P37242|THB_MOUSE
Thyroid hormone receptor beta
Search

THRB

0.94	Thyroid hormone receptor beta

0.79	GO:0030522	intracellular receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0008050	female courtship behavior
0.55	GO:0060509	Type I pneumocyte differentiation
0.55	GO:0007621	negative regulation of female receptivity
0.51	GO:0008016	regulation of heart contraction

0.85	GO:0004887	thyroid hormone receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.57	GO:0070324	thyroid hormone binding
0.52	GO:0031490	chromatin DNA binding
0.46	GO:0019899	enzyme binding
0.39	GO:0000989	transcription factor activity, transcription factor binding
0.36	GO:0003690	double-stranded DNA binding
0.35	GO:0046983	protein dimerization activity

0.61	GO:0005634	nucleus
0.47	GO:0000785	chromatin
0.45	GO:0031974	membrane-enclosed lumen
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P37804|TAGL_MOUSE
Transgelin
Search

TAGLN

0.81	Transgelin

0.51	GO:0030855	epithelial cell differentiation
0.41	GO:0000122	negative regulation of transcription by RNA polymerase II
0.39	GO:0007010	cytoskeleton organization
0.38	GO:0000902	cell morphogenesis
0.38	GO:0030029	actin filament-based process
0.36	GO:0033227	dsRNA transport
0.35	GO:0048731	system development
0.34	GO:0061061	muscle structure development

0.77	GO:0051015	actin filament binding
0.36	GO:0051032	nucleic acid transmembrane transporter activity
0.34	GO:0030674	protein binding, bridging

0.42	GO:0043209	myelin sheath
0.38	GO:0015629	actin cytoskeleton
0.37	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P37889|FBLN2_MOUSE
Fibulin-2
Search

FBLN2

0.70

Fibulin-2

0.81	GO:0030198	extracellular matrix organization
0.58	GO:0010952	positive regulation of peptidase activity
0.45	GO:0010811	positive regulation of cell-substrate adhesion
0.36	GO:0060317	cardiac epithelial to mesenchymal transition

0.69	GO:0005509	calcium ion binding
0.59	GO:0016504	peptidase activator activity
0.45	GO:0050840	extracellular matrix binding
0.32	GO:0005515	protein binding

0.74	GO:0031012	extracellular matrix
0.42	GO:0005615	extracellular space
0.33	GO:1903561	extracellular vesicle

sp|P37913|DNLI1_MOUSE
DNA ligase 1
Search

LIG1

0.47	Ligase I, DNA, ATP-dependent

0.79	GO:0051103	DNA ligation involved in DNA repair
0.66	GO:0071897	DNA biosynthetic process
0.65	GO:0006310	DNA recombination
0.65	GO:0006260	DNA replication
0.48	GO:0022616	DNA strand elongation
0.48	GO:0006284	base-excision repair
0.46	GO:1903047	mitotic cell cycle process
0.39	GO:0016070	RNA metabolic process
0.38	GO:0042542	response to hydrogen peroxide
0.37	GO:0006303	double-strand break repair via nonhomologous end joining

0.78	GO:0003910	DNA ligase (ATP) activity
0.54	GO:0003677	DNA binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0046872	metal ion binding
0.33	GO:0003700	DNA binding transcription factor activity

0.46	GO:0005654	nucleoplasm
0.41	GO:0005739	mitochondrion

0.78

EC:6.5.1.1

GO:0003910

sp|P38060|HMGCL_MOUSE
Hydroxymethylglutaryl-CoA lyase, mitochondrial
Search

HMGCL

0.47	Hydroxymethylglutaryl-CoA lyase

0.70	GO:0046951	ketone body biosynthetic process
0.52	GO:0051262	protein tetramerization
0.50	GO:0007005	mitochondrion organization
0.44	GO:0006629	lipid metabolic process
0.38	GO:0070542	response to fatty acid
0.38	GO:0001889	liver development
0.38	GO:0007584	response to nutrient
0.37	GO:0042594	response to starvation
0.36	GO:0035383	thioester metabolic process
0.36	GO:0006012	galactose metabolic process

0.81	GO:0004419	hydroxymethylglutaryl-CoA lyase activity
0.50	GO:0042803	protein homodimerization activity
0.48	GO:0030145	manganese ion binding
0.48	GO:0005102	receptor binding
0.45	GO:0000287	magnesium ion binding
0.38	GO:0000062	fatty-acyl-CoA binding
0.37	GO:0003978	UDP-glucose 4-epimerase activity
0.36	GO:0043177	organic acid binding
0.36	GO:0004560	alpha-L-fucosidase activity
0.32	GO:0016740	transferase activity

0.51	GO:0005777	peroxisome
0.44	GO:0044429	mitochondrial part
0.44	GO:0019866	organelle inner membrane
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005829	cytosol
0.38	GO:0005783	endoplasmic reticulum
0.37	GO:0031974	membrane-enclosed lumen

0.81	EC:4.1.3.4	GO:0004419
0.81	KEGG:R01360	GO:0004419

sp|P38532|HSF1_MOUSE
Heat shock factor protein 1
Search

HSF1

0.94	Heat shock transcription factor 1

0.58	GO:0072738	cellular response to diamide
0.58	GO:1900365	positive regulation of mRNA polyadenylation
0.58	GO:1903936	cellular response to sodium arsenite
0.57	GO:0043497	regulation of protein heterodimerization activity
0.57	GO:0071280	cellular response to copper ion
0.56	GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0060136	embryonic process involved in female pregnancy
0.56	GO:1900034	regulation of cellular response to heat

0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0061770	translation elongation factor binding
0.57	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding
0.55	GO:0051879	Hsp90 protein binding
0.55	GO:1990841	promoter-specific chromatin binding
0.54	GO:0043621	protein self-association
0.53	GO:0031490	chromatin DNA binding
0.51	GO:0019901	protein kinase binding
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding

0.61	GO:0005634	nucleus
0.55	GO:0097431	mitotic spindle pole
0.51	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0035770	ribonucleoprotein granule
0.51	GO:0000776	kinetochore
0.51	GO:0005813	centrosome
0.47	GO:0005829	cytosol
0.47	GO:0070013	intracellular organelle lumen
0.43	GO:0000791	euchromatin
0.42	GO:0000792	heterochromatin

sp|P38533|HSF2_MOUSE
Heat shock factor protein 2
Search

HSF2

0.97	LOW QUALITY PROTEIN: heat shock factor protein 2

0.68	GO:0006357	regulation of transcription by RNA polymerase II
0.53	GO:0006366	transcription by RNA polymerase II
0.52	GO:0045893	positive regulation of transcription, DNA-templated
0.52	GO:0007283	spermatogenesis
0.40	GO:0070207	protein homotrimerization
0.39	GO:1903935	response to sodium arsenite
0.37	GO:0009628	response to abiotic stimulus
0.37	GO:0031397	negative regulation of protein ubiquitination
0.37	GO:1901698	response to nitrogen compound
0.37	GO:0050821	protein stabilization

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.61	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.50	GO:0042803	protein homodimerization activity
0.37	GO:0001047	core promoter binding
0.35	GO:1990841	promoter-specific chromatin binding
0.35	GO:0003713	transcription coactivator activity
0.35	GO:0043621	protein self-association

0.61	GO:0005634	nucleus
0.49	GO:0070013	intracellular organelle lumen
0.44	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm
0.36	GO:0005694	chromosome
0.35	GO:0035770	ribonucleoprotein granule
0.34	GO:0015630	microtubule cytoskeleton
0.33	GO:0043234	protein complex

sp|P38575|UPK2_MOUSE
Uroplakin-2
Search

UPK2

0.97	Uroplakin-2

0.68	GO:0030855	epithelial cell differentiation
0.36	GO:0007275	multicellular organism development
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.37	GO:0005515	protein binding
0.35	GO:0043565	sequence-specific DNA binding
0.35	GO:0003700	DNA binding transcription factor activity

0.55	GO:0016324	apical plasma membrane
0.41	GO:0070062	extracellular exosome
0.38	GO:0005887	integral component of plasma membrane
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0005634	nucleus

sp|P38585|TTL_MOUSE
Tubulin--tyrosine ligase
Search

TTL

0.88	Tubulin--tyrosine ligase

0.62	GO:0018166	C-terminal protein-tyrosinylation
0.59	GO:0090235	regulation of metaphase plate congression
0.55	GO:0030516	regulation of axon extension
0.55	GO:0045931	positive regulation of mitotic cell cycle
0.51	GO:0000226	microtubule cytoskeleton organization

0.61	GO:0004835	tubulin-tyrosine ligase activity
0.40	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005874	microtubule
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.61

EC:6.3.2.25

GO:0004835

sp|P38640|UF02_MOUSE
Unknown protein from 2D-PAGE of fibroblasts (Fragment)
Search

0.10	Unknown protein from 2D-PAGE of fibroblasts (Fragment)

sp|P38641|UF03_MOUSE
Unknown protein from 2D-PAGE of fibroblasts (Fragment)
Search

0.10	Unknown protein from 2D-PAGE of fibroblasts (Fragment)

sp|P38642|UF04_MOUSE
Unknown protein from 2D-PAGE of fibroblasts (Fragment)
Search

0.10	Unknown protein from 2D-PAGE of fibroblasts (Fragment)

sp|P38643|UF05_MOUSE
Unknown protein from 2D-PAGE of fibroblasts (Fragment)
Search

0.10	Unknown protein from 2D-PAGE of fibroblasts (Fragment)

sp|P38644|UF06_MOUSE
Unknown protein from 2D-PAGE of fibroblasts (Fragment)
Search

0.10	Unknown protein from 2D-PAGE of fibroblasts (Fragment)

sp|P38647|GRP75_MOUSE
Stress-70 protein, mitochondrial
Search

HSPA9

0.85	LOW QUALITY PROTEIN: stress-70 protein, mitochondrial

0.68	GO:0006457	protein folding
0.63	GO:1902037	negative regulation of hematopoietic stem cell differentiation
0.62	GO:0045647	negative regulation of erythrocyte differentiation
0.59	GO:0030218	erythrocyte differentiation
0.56	GO:0006611	protein export from nucleus
0.53	GO:0016226	iron-sulfur cluster assembly
0.41	GO:0071345	cellular response to cytokine stimulus
0.41	GO:0060548	negative regulation of cell death
0.40	GO:0097068	response to thyroxine
0.40	GO:0051593	response to folic acid

0.70	GO:0051082	unfolded protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.39	GO:0017134	fibroblast growth factor binding
0.38	GO:0031072	heat shock protein binding
0.38	GO:0051087	chaperone binding
0.37	GO:0003723	RNA binding

0.54	GO:0042645	mitochondrial nucleoid
0.54	GO:0043209	myelin sheath
0.46	GO:0005730	nucleolus
0.42	GO:0031012	extracellular matrix
0.41	GO:0005925	focal adhesion
0.41	GO:0070062	extracellular exosome

sp|P38649|BGAT_MOUSE
Histo-blood group ABO system transferase
Search

ABO

0.84	Histo-blood group ABO system transferase

0.60	GO:0005975	carbohydrate metabolic process
0.43	GO:0030259	lipid glycosylation
0.42	GO:0009247	glycolipid biosynthetic process
0.37	GO:0006486	protein glycosylation
0.35	GO:0009624	response to nematode
0.35	GO:0032526	response to retinoic acid
0.34	GO:0008284	positive regulation of cell proliferation
0.34	GO:0043066	negative regulation of apoptotic process
0.34	GO:0042742	defense response to bacterium

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.43	GO:0140103	catalytic activity, acting on a glycoprotein
0.43	GO:0008194	UDP-glycosyltransferase activity
0.39	GO:0003823	antigen binding
0.37	GO:0030145	manganese ion binding
0.34	GO:1901265	nucleoside phosphate binding
0.34	GO:0036094	small molecule binding
0.33	GO:0005515	protein binding

0.41	GO:0031982	vesicle
0.41	GO:0005794	Golgi apparatus
0.37	GO:0098588	bounding membrane of organelle
0.36	GO:0031984	organelle subcompartment
0.36	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.69

GO:0016758

sp|P39038|CADH4_MOUSE
Cadherin-4
Search

CDH4

0.96	Cadherin 4, type 1, R-cadherin (retinal)

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.56	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.54	GO:0045773	positive regulation of axon extension
0.51	GO:0007411	axon guidance
0.42	GO:1902897	regulation of postsynaptic density protein 95 clustering
0.42	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly
0.41	GO:2000809	positive regulation of synaptic vesicle clustering
0.41	GO:0009966	regulation of signal transduction
0.41	GO:0070445	regulation of oligodendrocyte progenitor proliferation
0.41	GO:0044331	cell-cell adhesion mediated by cadherin

0.70	GO:0005509	calcium ion binding
0.41	GO:0045295	gamma-catenin binding
0.41	GO:0045294	alpha-catenin binding
0.40	GO:0019903	protein phosphatase binding
0.40	GO:0008013	beta-catenin binding
0.39	GO:0019901	protein kinase binding
0.38	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.41	GO:0005916	fascia adherens
0.40	GO:0014069	postsynaptic density
0.40	GO:0030027	lamellipodium
0.39	GO:0030864	cortical actin cytoskeleton
0.39	GO:0045121	membrane raft
0.39	GO:0045177	apical part of cell
0.38	GO:0009986	cell surface
0.38	GO:0019898	extrinsic component of membrane
0.38	GO:0031012	extracellular matrix

sp|P39039|MBL1_MOUSE
Mannose-binding protein A
Search

MBL2

0.85	Pulmonary surfactant-associated protein A

0.85	GO:0001867	complement activation, lectin pathway
0.52	GO:0044130	negative regulation of growth of symbiont in host
0.51	GO:0006958	complement activation, classical pathway
0.50	GO:0050830	defense response to Gram-positive bacterium
0.49	GO:0048525	negative regulation of viral process
0.47	GO:0051873	killing by host of symbiont cells
0.45	GO:0050766	positive regulation of phagocytosis
0.38	GO:0070207	protein homotrimerization
0.36	GO:0051289	protein homotetramerization
0.35	GO:0008228	opsonization

0.85	GO:0005537	mannose binding
0.50	GO:0048306	calcium-dependent protein binding
0.44	GO:0005102	receptor binding
0.43	GO:0005509	calcium ion binding
0.38	GO:0005201	extracellular matrix structural constituent
0.37	GO:0002020	protease binding
0.37	GO:0070273	phosphatidylinositol-4-phosphate binding
0.35	GO:0001871	pattern binding
0.35	GO:0042803	protein homodimerization activity
0.35	GO:0043621	protein self-association

0.71	GO:0005581	collagen trimer
0.49	GO:0005576	extracellular region
0.34	GO:0009986	cell surface
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004252

sp|P39053|DYN1_MOUSE
Dynamin-1
Search

DNM1

0.93	Dynamin 1 short form

0.73	GO:0072583	clathrin-dependent endocytosis
0.54	GO:0016185	synaptic vesicle budding from presynaptic endocytic zone membrane
0.53	GO:0051932	synaptic transmission, GABAergic
0.51	GO:0007032	endosome organization
0.50	GO:0008344	adult locomotory behavior
0.49	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission
0.49	GO:0007605	sensory perception of sound
0.49	GO:1901998	toxin transport
0.49	GO:0051262	protein tetramerization
0.47	GO:0000266	mitochondrial fission

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0019901	protein kinase binding
0.46	GO:0042802	identical protein binding
0.44	GO:0046983	protein dimerization activity
0.44	GO:0008017	microtubule binding
0.39	GO:0031749	D2 dopamine receptor binding

0.51	GO:0001917	photoreceptor inner segment
0.50	GO:0043209	myelin sheath
0.47	GO:0045202	synapse
0.47	GO:0030117	membrane coat
0.46	GO:0005654	nucleoplasm
0.40	GO:0031966	mitochondrial membrane
0.39	GO:0043196	varicosity
0.38	GO:0099503	secretory vesicle
0.37	GO:0005874	microtubule
0.37	GO:0030133	transport vesicle

sp|P39054|DYN2_MOUSE
Dynamin-2
Search

DNM2

0.94	Putative vacuolar sorting protein vps1 dynamin

0.71	GO:0006897	endocytosis
0.55	GO:1903526	negative regulation of membrane tubulation
0.53	GO:0033572	transferrin transport
0.53	GO:0060976	coronary vasculature development
0.53	GO:0035904	aorta development
0.52	GO:0003281	ventricular septum development
0.50	GO:0043112	receptor metabolic process
0.48	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission
0.46	GO:0000266	mitochondrial fission
0.43	GO:0060026	convergent extension

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.50	GO:0017124	SH3 domain binding
0.43	GO:0008017	microtubule binding
0.40	GO:0031749	D2 dopamine receptor binding
0.39	GO:0050998	nitric-oxide synthase binding
0.39	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding
0.39	GO:0050699	WW domain binding
0.37	GO:0019901	protein kinase binding
0.37	GO:0032403	protein complex binding

0.73	GO:0005874	microtubule
0.53	GO:0001917	photoreceptor inner segment
0.50	GO:0045211	postsynaptic membrane
0.46	GO:0005794	Golgi apparatus
0.45	GO:0005829	cytosol
0.40	GO:0030670	phagocytic vesicle membrane
0.40	GO:0001891	phagocytic cup
0.39	GO:0031966	mitochondrial membrane
0.39	GO:0030426	growth cone
0.39	GO:0014069	postsynaptic density

sp|P39061|COIA1_MOUSE
Collagen alpha-1(XVIII) chain
Search

COL18A1

0.72	Type XVIII collagen short variant

0.69	GO:0007155	cell adhesion
0.53	GO:0001886	endothelial cell morphogenesis
0.53	GO:2000353	positive regulation of endothelial cell apoptotic process
0.49	GO:0001525	angiogenesis
0.49	GO:0030335	positive regulation of cell migration
0.49	GO:0030198	extracellular matrix organization
0.48	GO:0008284	positive regulation of cell proliferation
0.46	GO:0001755	neural crest cell migration
0.40	GO:0051599	response to hydrostatic pressure
0.36	GO:0042493	response to drug

0.60	GO:0005198	structural molecule activity
0.33	GO:0042802	identical protein binding
0.33	GO:0017147	Wnt-protein binding
0.33	GO:0042813	Wnt-activated receptor activity
0.33	GO:0046872	metal ion binding
0.32	GO:0004930	G-protein coupled receptor activity

0.75	GO:0005581	collagen trimer
0.72	GO:0031012	extracellular matrix
0.48	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.34	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016020	membrane

sp|P39087|GRIK2_MOUSE
Glutamate receptor ionotropic, kainate 2
Search

GRIK2

0.82	Glutamate ionotropic receptor kainate type subunit 2

0.78	GO:0060079	excitatory postsynaptic potential
0.75	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0034220	ion transmembrane transport
0.56	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.55	GO:0051967	negative regulation of synaptic transmission, glutamatergic
0.54	GO:0060080	inhibitory postsynaptic potential
0.54	GO:0050806	positive regulation of synaptic transmission
0.53	GO:0035249	synaptic transmission, glutamatergic
0.53	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.53	GO:0001662	behavioral fear response

0.80	GO:0005234	extracellularly glutamate-gated ion channel activity
0.75	GO:0004970	ionotropic glutamate receptor activity
0.52	GO:0099094	ligand-gated cation channel activity
0.52	GO:0005272	sodium channel activity
0.50	GO:0098782	mechanosensitived potassium channel activity
0.39	GO:0031624	ubiquitin conjugating enzyme binding
0.38	GO:0030165	PDZ domain binding
0.38	GO:0042803	protein homodimerization activity
0.37	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0016595	glutamate binding

0.77	GO:0045211	postsynaptic membrane
0.72	GO:0030054	cell junction
0.55	GO:0032983	kainate selective glutamate receptor complex
0.52	GO:0042734	presynaptic membrane
0.51	GO:0014069	postsynaptic density
0.50	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite
0.39	GO:0030424	axon
0.39	GO:0043679	axon terminus
0.38	GO:0120111	neuron projection cytoplasm

sp|P39098|MA1A2_MOUSE
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB
Search

MAN1A2

0.47	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

0.53	GO:0007585	respiratory gaseous exchange
0.53	GO:0048286	lung alveolus development
0.50	GO:0009100	glycoprotein metabolic process
0.36	GO:0043413	macromolecule glycosylation
0.34	GO:1901137	carbohydrate derivative biosynthetic process
0.34	GO:0036211	protein modification process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:1901566	organonitrogen compound biosynthetic process
0.33	GO:0009059	macromolecule biosynthetic process
0.33	GO:0044249	cellular biosynthetic process

0.82	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.70	GO:0005509	calcium ion binding

0.51	GO:0005794	Golgi apparatus
0.49	GO:0098588	bounding membrane of organelle
0.48	GO:0031984	organelle subcompartment
0.43	GO:0005783	endoplasmic reticulum
0.38	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.36	GO:0070062	extracellular exosome
0.36	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.82	EC:3.2.1.113	GO:0004571
0.82	KEGG:R05982 KEGG:R06722	GO:0004571

sp|P39428|TRAF1_MOUSE
TNF receptor-associated factor 1
Search

TRAF1

0.85	Epstein-Barr virus-induced protein 6

0.74	GO:0042981	regulation of apoptotic process
0.64	GO:0051090	regulation of DNA binding transcription factor activity
0.62	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.59	GO:0048583	regulation of response to stimulus
0.57	GO:0008063	Toll signaling pathway
0.56	GO:0044093	positive regulation of molecular function
0.55	GO:0048518	positive regulation of biological process
0.54	GO:0002697	regulation of immune effector process
0.54	GO:0010646	regulation of cell communication
0.54	GO:0023051	regulation of signaling

0.83	GO:0005164	tumor necrosis factor receptor binding
0.64	GO:0031996	thioesterase binding
0.62	GO:0008270	zinc ion binding
0.57	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0042802	identical protein binding
0.45	GO:0004842	ubiquitin-protein transferase activity
0.44	GO:0019903	protein phosphatase binding
0.42	GO:0019901	protein kinase binding
0.33	GO:0004866	endopeptidase inhibitor activity
0.32	GO:0003676	nucleic acid binding

0.46	GO:0035631	CD40 receptor complex
0.42	GO:0009898	cytoplasmic side of plasma membrane
0.36	GO:0005622	intracellular
0.33	GO:0031982	vesicle
0.33	GO:0012505	endomembrane system
0.33	GO:0005615	extracellular space

0.45

GO:0004842

sp|P39429|TRAF2_MOUSE
TNF receptor-associated factor 2
Search

TRAF2

0.90	TNF receptor-associated factor 2

0.84	GO:0007250	activation of NF-kappaB-inducing kinase activity
0.82	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.81	GO:0051865	protein autoubiquitination
0.79	GO:0046328	regulation of JNK cascade
0.74	GO:0042981	regulation of apoptotic process
0.70	GO:1903721	positive regulation of I-kappaB phosphorylation
0.69	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway
0.68	GO:0071732	cellular response to nitric oxide
0.67	GO:0090073	positive regulation of protein homodimerization activity
0.67	GO:0051023	regulation of immunoglobulin secretion

0.79	GO:0005164	tumor necrosis factor receptor binding
0.70	GO:0004842	ubiquitin-protein transferase activity
0.69	GO:0005174	CD40 receptor binding
0.67	GO:0031996	thioesterase binding
0.67	GO:0046625	sphingolipid binding
0.63	GO:0008270	zinc ion binding
0.63	GO:0019903	protein phosphatase binding
0.60	GO:0031625	ubiquitin protein ligase binding
0.60	GO:0019901	protein kinase binding
0.57	GO:0042802	identical protein binding

0.69	GO:0097057	TRAF2-GSTP1 complex
0.69	GO:1990597	AIP1-IRE1 complex
0.69	GO:1990604	IRE1-TRAF2-ASK1 complex
0.68	GO:0035631	CD40 receptor complex
0.61	GO:0098857	membrane microdomain
0.59	GO:0009898	cytoplasmic side of plasma membrane
0.59	GO:0012506	vesicle membrane
0.58	GO:0000151	ubiquitin ligase complex
0.54	GO:0005829	cytosol
0.42	GO:0005938	cell cortex

0.70

GO:0004842

sp|P39447|ZO1_MOUSE
Tight junction protein ZO-1
Search

TJP1

0.91	Tight junction protein ZO-1

0.53	GO:0007605	sensory perception of sound
0.52	GO:0001825	blastocyst formation
0.39	GO:0071000	response to magnetism
0.39	GO:0090557	establishment of endothelial intestinal barrier
0.39	GO:0043116	negative regulation of vascular permeability
0.38	GO:0071333	cellular response to glucose stimulus
0.38	GO:0045471	response to ethanol
0.38	GO:0007043	cell-cell junction assembly
0.38	GO:0032496	response to lipopolysaccharide
0.37	GO:1901350	cell-cell signaling involved in cell-cell junction organization

0.56	GO:0071253	connexin binding
0.50	GO:0019904	protein domain specific binding
0.39	GO:0005516	calmodulin binding
0.38	GO:0008022	protein C-terminus binding
0.38	GO:0045296	cadherin binding
0.31	GO:0016301	kinase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.81	GO:0005923	bicellular tight junction
0.56	GO:0046581	intercellular canaliculus
0.55	GO:0016327	apicolateral plasma membrane
0.55	GO:0014704	intercalated disc
0.54	GO:0005913	cell-cell adherens junction
0.52	GO:0045177	apical part of cell
0.46	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.43	GO:0043234	protein complex
0.39	GO:0005921	gap junction

sp|P39654|LOX15_MOUSE
Arachidonate 15-lipoxygenase
Search

ALOX15

0.93	Arachidonate lipoxygenase, epidermal

0.66	GO:0019372	lipoxygenase pathway
0.64	GO:0019369	arachidonic acid metabolic process
0.62	GO:2001303	lipoxin A4 biosynthetic process
0.55	GO:0035963	cellular response to interleukin-13
0.54	GO:0030155	regulation of cell adhesion
0.53	GO:1901751	leukotriene A4 metabolic process
0.53	GO:2001304	lipoxin B4 metabolic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0043651	linoleic acid metabolic process
0.52	GO:1901074	regulation of engulfment of apoptotic cell

0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.62	GO:0005506	iron ion binding
0.51	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.47	GO:0047977	hepoxilin-epoxide hydrolase activity
0.44	GO:0051120	hepoxilin A3 synthase activity
0.37	GO:0097260	eoxin A4 synthase activity
0.36	GO:0019870	potassium channel inhibitor activity
0.34	GO:0005515	protein binding
0.34	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)

0.50	GO:0005829	cytosol
0.50	GO:0005811	lipid droplet
0.49	GO:0042383	sarcolemma
0.49	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus

0.75

EC:1.13.11

GO:0016702

sp|P39655|LOX12_MOUSE
Arachidonate 12-lipoxygenase, 12S-type
Search

ALOX12

0.93	Arachidonate 12-lipoxygenase, epidermal-type

0.65	GO:0019372	lipoxygenase pathway
0.62	GO:0019369	arachidonic acid metabolic process
0.61	GO:2001301	lipoxin biosynthetic process
0.61	GO:2001302	lipoxin A4 metabolic process
0.57	GO:0006691	leukotriene metabolic process
0.57	GO:0042759	long-chain fatty acid biosynthetic process
0.55	GO:2001304	lipoxin B4 metabolic process
0.54	GO:0090331	negative regulation of platelet aggregation
0.54	GO:0043651	linoleic acid metabolic process
0.54	GO:0097176	epoxide metabolic process

0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.63	GO:0005506	iron ion binding
0.47	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.45	GO:0047977	hepoxilin-epoxide hydrolase activity
0.41	GO:0051120	hepoxilin A3 synthase activity
0.36	GO:0097260	eoxin A4 synthase activity
0.35	GO:0019870	potassium channel inhibitor activity
0.34	GO:0005515	protein binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0004464	leukotriene-C4 synthase activity

0.51	GO:0005829	cytosol
0.51	GO:0042383	sarcolemma
0.46	GO:0005811	lipid droplet
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.45	GO:0005641	nuclear envelope lumen
0.44	GO:0016363	nuclear matrix
0.43	GO:0031965	nuclear membrane
0.40	GO:0005654	nucleoplasm
0.37	GO:0070062	extracellular exosome
0.34	GO:1904813	ficolin-1-rich granule lumen

0.75	EC:1.13.11	GO:0016702
0.34	KEGG:R03059	GO:0004464

sp|P39688|FYN_MOUSE
Tyrosine-protein kinase Fyn
Search

FYN

0.65	Tyrosine-protein kinase Fyn

0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.72	GO:0050852	T cell receptor signaling pathway
0.69	GO:0042110	T cell activation
0.69	GO:1902951	negative regulation of dendritic spine maintenance
0.68	GO:0046777	protein autophosphorylation
0.67	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain
0.67	GO:1905430	cellular response to glycine
0.67	GO:0036120	cellular response to platelet-derived growth factor stimulus
0.67	GO:0001764	neuron migration
0.66	GO:0090314	positive regulation of protein targeting to membrane

0.75	GO:0004713	protein tyrosine kinase activity
0.65	GO:0042610	CD8 receptor binding
0.65	GO:0097718	disordered domain specific binding
0.64	GO:0046875	ephrin receptor binding
0.64	GO:0031802	type 5 metabotropic glutamate receptor binding
0.64	GO:0044325	ion channel binding
0.63	GO:0042608	T cell receptor binding
0.62	GO:0070851	growth factor receptor binding
0.62	GO:0051428	peptide hormone receptor binding
0.61	GO:0043548	phosphatidylinositol 3-kinase binding

0.67	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.64	GO:0098857	membrane microdomain
0.63	GO:0014069	postsynaptic density
0.62	GO:0005884	actin filament
0.61	GO:0030425	dendrite
0.58	GO:0005768	endosome
0.57	GO:0005829	cytosol
0.49	GO:0005634	nucleus
0.46	GO:0005739	mitochondrion

0.75	EC:2.7.10	GO:0004713
0.49	KEGG:R04545	GO:0046934

sp|P39689|CDN1A_MOUSE
Cyclin-dependent kinase inhibitor 1
Search

CDKN1A

0.91	Cyclin-dependent kinase inhibitor 1

0.84	GO:0072331	signal transduction by p53 class mediator
0.83	GO:0007050	cell cycle arrest
0.82	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.76	GO:0007346	regulation of mitotic cell cycle
0.71	GO:1902400	intracellular signal transduction involved in G1 DNA damage checkpoint
0.70	GO:1904030	negative regulation of cyclin-dependent protein kinase activity
0.70	GO:0071493	cellular response to UV-B
0.70	GO:0042772	DNA damage response, signal transduction resulting in transcription
0.70	GO:0090398	cellular senescence
0.70	GO:0033158	regulation of protein import into nucleus, translocation

0.85	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.71	GO:0019912	cyclin-dependent protein kinase activating kinase activity
0.65	GO:0030332	cyclin binding
0.64	GO:0031625	ubiquitin protein ligase binding
0.63	GO:0019901	protein kinase binding
0.61	GO:0032403	protein complex binding
0.44	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.36	GO:0046872	metal ion binding
0.35	GO:0003735	structural constituent of ribosome

0.73	GO:0070557	PCNA-p21 complex
0.67	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.63	GO:0016604	nuclear body
0.59	GO:0005730	nucleolus
0.56	GO:0005829	cytosol
0.46	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005840	ribosome

0.71

GO:0019912

sp|P39749|FEN1_MOUSE
Flap endonuclease 1
Search

FEN1

0.64	Flap endonuclease 1-B

0.81	GO:0043137	DNA replication, removal of RNA primer
0.69	GO:0006284	base-excision repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.58	GO:0045876	positive regulation of sister chromatid cohesion
0.39	GO:0007613	memory
0.37	GO:0033260	nuclear DNA replication
0.37	GO:0009411	response to UV
0.37	GO:0098502	DNA dephosphorylation
0.37	GO:0000734	gene conversion at mating-type locus, DNA repair synthesis
0.36	GO:0035753	maintenance of DNA trinucleotide repeats

0.79	GO:0048256	flap endonuclease activity
0.74	GO:0008409	5'-3' exonuclease activity
0.72	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters
0.62	GO:0000287	magnesium ion binding
0.55	GO:0003677	DNA binding
0.50	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.38	GO:0008309	double-stranded DNA exodeoxyribonuclease activity
0.36	GO:0008297	single-stranded DNA exodeoxyribonuclease activity
0.35	GO:0030145	manganese ion binding
0.33	GO:0005515	protein binding

0.72	GO:0005730	nucleolus
0.68	GO:0005654	nucleoplasm
0.60	GO:0005739	mitochondrion
0.53	GO:0000784	nuclear chromosome, telomeric region
0.43	GO:0043234	protein complex
0.36	GO:0035861	site of double-strand break
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.72

EC:3.1.21

GO:0016888

sp|P39876|TIMP3_MOUSE
Metalloproteinase inhibitor 3
Search

TIMP3

0.93	TIMP metallopeptidase inhibitor 3

0.76	GO:0010951	negative regulation of endopeptidase activity
0.74	GO:0051045	negative regulation of membrane protein ectodomain proteolysis
0.73	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway
0.68	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.61	GO:1904683	regulation of metalloendopeptidase activity
0.61	GO:1905049	negative regulation of metallopeptidase activity
0.55	GO:0010033	response to organic substance
0.49	GO:0070887	cellular response to chemical stimulus
0.36	GO:0007219	Notch signaling pathway

0.85	GO:0008191	metalloendopeptidase inhibitor activity
0.50	GO:0002020	protease binding

0.66

GO:0005576

extracellular region

sp|P40124|CAP1_MOUSE
Adenylyl cyclase-associated protein 1
Search

CAP1

0.74	Adenylyl cyclase-associated protein 1

0.71	GO:0007010	cytoskeleton organization
0.69	GO:0030029	actin filament-based process
0.54	GO:0001667	ameboidal-type cell migration
0.52	GO:0000902	cell morphogenesis
0.50	GO:0045761	regulation of adenylate cyclase activity
0.49	GO:0007163	establishment or maintenance of cell polarity
0.47	GO:0006898	receptor-mediated endocytosis
0.47	GO:0097435	supramolecular fiber organization
0.42	GO:0007165	signal transduction
0.41	GO:0001756	somitogenesis

0.73	GO:0003779	actin binding
0.53	GO:0008179	adenylate cyclase binding
0.42	GO:0042802	identical protein binding
0.33	GO:0003735	structural constituent of ribosome

0.56	GO:0030864	cortical actin cytoskeleton
0.48	GO:0005615	extracellular space
0.45	GO:0014069	postsynaptic density
0.36	GO:0005925	focal adhesion
0.36	GO:1903561	extracellular vesicle
0.36	GO:0005886	plasma membrane
0.35	GO:0035578	azurophil granule lumen
0.34	GO:0015934	large ribosomal subunit
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P40142|TKT_MOUSE
Transketolase
Search

TKT

0.46	Transketolase

0.57	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process
0.51	GO:0040008	regulation of growth
0.37	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.36	GO:0009052	pentose-phosphate shunt, non-oxidative branch
0.36	GO:0005999	xylulose biosynthetic process
0.36	GO:0043085	positive regulation of catalytic activity
0.33	GO:0046390	ribose phosphate biosynthetic process

0.53	GO:0004802	transketolase activity
0.50	GO:0042803	protein homodimerization activity
0.41	GO:0048037	cofactor binding
0.36	GO:0008047	enzyme activator activity
0.35	GO:0046872	metal ion binding
0.34	GO:0048029	monosaccharide binding
0.34	GO:1901681	sulfur compound binding
0.33	GO:0019842	vitamin binding
0.32	GO:0043168	anion binding
0.32	GO:1901363	heterocyclic compound binding

0.53	GO:0043209	myelin sheath
0.52	GO:0016607	nuclear speck
0.36	GO:0070062	extracellular exosome
0.36	GO:0042579	microbody
0.34	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005829	cytosol

0.53

EC:2.2.1.1

GO:0004802

sp|P40201|CHD1_MOUSE
Chromodomain-helicase-DNA-binding protein 1
Search

CHD1

0.86	Z-linked chromodomain helicase DNA binding protein 1

0.58	GO:0043923	positive regulation by host of viral transcription
0.51	GO:0016569	covalent chromatin modification
0.48	GO:0006338	chromatin remodeling
0.35	GO:0006333	chromatin assembly or disassembly
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.34	GO:0032392	DNA geometric change
0.34	GO:0000165	MAPK cascade

0.56	GO:0140034	methylation-dependent protein binding
0.55	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0042393	histone binding
0.46	GO:0003677	DNA binding
0.35	GO:0003682	chromatin binding
0.34	GO:0008094	DNA-dependent ATPase activity
0.34	GO:0004707	MAP kinase activity

0.60	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.44	GO:0043232	intracellular non-membrane-bounded organelle
0.43	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:2.7.11.24	GO:0004707
0.34	KEGG:R00162	GO:0004707

sp|P40223|CSF3R_MOUSE
Granulocyte colony-stimulating factor receptor
Search

CSF3R

0.88	Colony stimulating factor 3 receptor

0.76	GO:0019221	cytokine-mediated signaling pathway
0.75	GO:0030593	neutrophil chemotaxis
0.73	GO:0045637	regulation of myeloid cell differentiation
0.44	GO:0097186	amelogenesis
0.37	GO:1901534	positive regulation of hematopoietic progenitor cell differentiation
0.36	GO:0030223	neutrophil differentiation
0.36	GO:1903131	mononuclear cell differentiation
0.36	GO:0030225	macrophage differentiation
0.36	GO:0060216	definitive hemopoiesis
0.36	GO:0035162	embryonic hemopoiesis

0.82	GO:0051916	granulocyte colony-stimulating factor binding
0.78	GO:0004896	cytokine receptor activity

0.30

GO:0016020

membrane

sp|P40224|SDF1_MOUSE
Stromal cell-derived factor 1
Search

CXCL12

0.93	C-X-C motif chemokine ligand 12

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.72	GO:1903237	negative regulation of leukocyte tethering or rolling
0.71	GO:2000669	negative regulation of dendritic cell apoptotic process
0.70	GO:0006952	defense response
0.69	GO:2000406	positive regulation of T cell migration
0.69	GO:0090026	positive regulation of monocyte chemotaxis
0.69	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.67	GO:0070098	chemokine-mediated signaling pathway
0.61	GO:0045785	positive regulation of cell adhesion

0.84	GO:0008009	chemokine activity
0.71	GO:0045236	CXCR chemokine receptor binding
0.50	GO:0042056	chemoattractant activity

0.66	GO:0005576	extracellular region
0.50	GO:0009897	external side of plasma membrane
0.40	GO:0031982	vesicle
0.35	GO:0005737	cytoplasm

sp|P40226|TPO_MOUSE
Thrombopoietin
Search

THPO

0.97	Thrombopoietin

0.80	GO:0008283	cell proliferation
0.77	GO:0038163	thrombopoietin-mediated signaling pathway
0.76	GO:0045654	positive regulation of megakaryocyte differentiation
0.76	GO:0010469	regulation of receptor activity
0.76	GO:1902035	positive regulation of hematopoietic stem cell proliferation
0.71	GO:0051897	positive regulation of protein kinase B signaling
0.70	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.68	GO:0030099	myeloid cell differentiation
0.39	GO:0071222	cellular response to lipopolysaccharide

0.81	GO:0005125	cytokine activity
0.79	GO:0005179	hormone activity
0.38	GO:0008083	growth factor activity

0.66

GO:0005576

extracellular region

sp|P40237|CD82_MOUSE
CD82 antigen
Search

CD82

0.59	Tetraspanin

0.44

GO:0007166

cell surface receptor signaling pathway

0.33

GO:0005515

protein binding

0.43	GO:0005887	integral component of plasma membrane
0.37	GO:0070062	extracellular exosome
0.32	GO:0005634	nucleus

sp|P40240|CD9_MOUSE
CD9 antigen
Search

CD9

0.60	Tetraspanin

0.56	GO:0090331	negative regulation of platelet aggregation
0.54	GO:0030913	paranodal junction assembly
0.54	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization
0.54	GO:0071404	cellular response to low-density lipoprotein particle stimulus
0.53	GO:0031623	receptor internalization
0.52	GO:0051271	negative regulation of cellular component movement
0.50	GO:0008285	negative regulation of cell proliferation
0.48	GO:0007155	cell adhesion
0.40	GO:0007166	cell surface receptor signaling pathway

0.51	GO:0070062	extracellular exosome
0.51	GO:0009897	external side of plasma membrane
0.39	GO:0005887	integral component of plasma membrane

sp|P40336|VP26A_MOUSE
Vacuolar protein sorting-associated protein 26A
Search

VPS26A

0.97	Vacuolar protein sorting-associated protein 26A-A

0.61	GO:0007165	signal transduction
0.54	GO:1990126	retrograde transport, endosome to plasma membrane
0.54	GO:0042147	retrograde transport, endosome to Golgi
0.43	GO:0006886	intracellular protein transport
0.35	GO:0016241	regulation of macroautophagy
0.34	GO:0198738	cell-cell signaling by wnt

0.44	GO:0008565	protein transporter activity
0.34	GO:0005515	protein binding
0.34	GO:0004386	helicase activity

0.55	GO:0097422	tubular endosome
0.54	GO:0030904	retromer complex
0.52	GO:0005769	early endosome
0.51	GO:0010008	endosome membrane
0.50	GO:0005764	lysosome
0.48	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome

sp|P40338|VHL_MOUSE
Von Hippel-Lindau disease tumor suppressor
Search

VHL

0.96	von Hippel-Lindau disease tumor suppressor

0.81	GO:1902072	negative regulation of hypoxia-inducible factor-1alpha signaling pathway
0.81	GO:0048877	homeostasis of number of retina cells
0.79	GO:0061073	ciliary body morphogenesis
0.78	GO:0070244	negative regulation of thymocyte apoptotic process
0.77	GO:0061072	iris morphogenesis
0.77	GO:0045602	negative regulation of endothelial cell differentiation
0.77	GO:0003310	pancreatic A cell differentiation
0.75	GO:0043534	blood vessel endothelial cell migration
0.75	GO:0048069	eye pigmentation
0.75	GO:0003309	type B pancreatic cell differentiation

0.66	GO:0032403	protein complex binding
0.63	GO:0061630	ubiquitin protein ligase activity
0.51	GO:0008134	transcription factor binding
0.51	GO:0019899	enzyme binding
0.37	GO:0004984	olfactory receptor activity
0.37	GO:0042803	protein homodimerization activity
0.36	GO:0046982	protein heterodimerization activity
0.36	GO:0004930	G-protein coupled receptor activity
0.36	GO:0004674	protein serine/threonine kinase activity
0.35	GO:0016874	ligase activity

0.75	GO:0031462	Cul2-RING ubiquitin ligase complex
0.70	GO:0030891	VCB complex
0.66	GO:0005929	cilium
0.63	GO:0005730	nucleolus
0.63	GO:0005654	nucleoplasm
0.44	GO:0031209	SCAR complex
0.44	GO:0005829	cytosol
0.41	GO:0005739	mitochondrion
0.38	GO:0005667	transcription factor complex
0.37	GO:0005783	endoplasmic reticulum

0.36

GO:0004674

sp|P40630|TFAM_MOUSE
Transcription factor A, mitochondrial
Search

TFAM

0.92	Mitochondrial transcription factor A

0.63	GO:0006391	transcription initiation from mitochondrial promoter
0.56	GO:0033108	mitochondrial respiratory chain complex assembly
0.54	GO:0045893	positive regulation of transcription, DNA-templated
0.51	GO:0006357	regulation of transcription by RNA polymerase II
0.37	GO:0006264	mitochondrial DNA replication
0.36	GO:0006356	regulation of transcription by RNA polymerase I
0.35	GO:0006366	transcription by RNA polymerase II
0.33	GO:0022900	electron transport chain

0.65	GO:0001018	mitochondrial promoter sequence-specific DNA binding
0.61	GO:0008301	DNA binding, bending
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0003682	chromatin binding
0.47	GO:0003700	DNA binding transcription factor activity
0.44	GO:0001223	transcription coactivator binding
0.41	GO:0031072	heat shock protein binding
0.35	GO:0003723	RNA binding
0.33	GO:0009055	electron transfer activity

0.61	GO:0005634	nucleus
0.59	GO:0042645	mitochondrial nucleoid
0.36	GO:0005829	cytosol
0.36	GO:0005667	transcription factor complex

sp|P40645|SOX6_MOUSE
Transcription factor SOX-6
Search

SOX6

0.89	Transcription factor SOX-6

0.70	GO:0007275	multicellular organism development
0.64	GO:2000741	positive regulation of mesenchymal stem cell differentiation
0.63	GO:2000726	negative regulation of cardiac muscle cell differentiation
0.63	GO:0032332	positive regulation of chondrocyte differentiation
0.59	GO:0001708	cell fate specification
0.59	GO:0071560	cellular response to transforming growth factor beta stimulus
0.58	GO:0061448	connective tissue development
0.58	GO:0034101	erythrocyte homeostasis
0.58	GO:0014706	striated muscle tissue development
0.58	GO:0042692	muscle cell differentiation

0.58	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.35	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|P40646|SOX7_MOUSE
Transcription factor SOX-7
Search

SOX7

0.91	Transcription factor SOX-7

0.52	GO:0007369	gastrulation
0.52	GO:0007492	endoderm development
0.49	GO:0030111	regulation of Wnt signaling pathway
0.47	GO:0048646	anatomical structure formation involved in morphogenesis
0.47	GO:0045893	positive regulation of transcription, DNA-templated
0.46	GO:0006357	regulation of transcription by RNA polymerase II
0.45	GO:0042127	regulation of cell proliferation
0.44	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.44	GO:0072001	renal system development
0.44	GO:0045892	negative regulation of transcription, DNA-templated

0.55	GO:0003677	DNA binding
0.48	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0008013	beta-catenin binding
0.40	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.39	GO:0003713	transcription coactivator activity
0.39	GO:0046982	protein heterodimerization activity
0.38	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.39	GO:0005667	transcription factor complex
0.38	GO:0070013	intracellular organelle lumen
0.37	GO:0044446	intracellular organelle part
0.35	GO:0005737	cytoplasm

sp|P40694|SMBP2_MOUSE
DNA-binding protein SMUBP-2
Search

IGHMBP2

0.94	Immunoglobulin mu binding protein 2

0.64	GO:0051260	protein homooligomerization
0.58	GO:0032392	DNA geometric change

0.77	GO:0032575	ATP-dependent 5'-3' RNA helicase activity
0.66	GO:0043141	ATP-dependent 5'-3' DNA helicase activity
0.63	GO:0008270	zinc ion binding
0.61	GO:0043022	ribosome binding
0.60	GO:0008134	transcription factor binding
0.57	GO:0000049	tRNA binding
0.55	GO:0030554	adenyl nucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding

0.52	GO:0005634	nucleus
0.43	GO:0005737	cytoplasm

0.66

EC:3.6.1

GO:0043141

sp|P40749|SYT4_MOUSE
Synaptotagmin-4
Search

SYT4

0.96	Synaptotagmin IV

0.74	GO:0006887	exocytosis
0.60	GO:0033604	negative regulation of catecholamine secretion
0.58	GO:1903861	positive regulation of dendrite extension
0.53	GO:0017158	regulation of calcium ion-dependent exocytosis
0.52	GO:1905433	negative regulation of retrograde trans-synaptic signaling by neuropeptide
0.52	GO:0048174	negative regulation of short-term neuronal synaptic plasticity
0.51	GO:0007269	neurotransmitter secretion
0.51	GO:0014049	positive regulation of glutamate secretion
0.50	GO:0050709	negative regulation of protein secretion
0.50	GO:0014059	regulation of dopamine secretion

0.51	GO:0005544	calcium-dependent phospholipid binding
0.48	GO:0000149	SNARE binding
0.47	GO:0030276	clathrin binding
0.46	GO:0005509	calcium ion binding
0.40	GO:0042803	protein homodimerization activity
0.39	GO:0048487	beta-tubulin binding
0.39	GO:0031625	ubiquitin protein ligase binding
0.39	GO:0031369	translation initiation factor binding
0.39	GO:0001786	phosphatidylserine binding
0.37	GO:0046982	protein heterodimerization activity

0.51	GO:1990742	microvesicle
0.50	GO:0097449	astrocyte projection
0.50	GO:0031045	dense core granule
0.50	GO:0098793	presynapse
0.48	GO:0043005	neuron projection
0.47	GO:0043025	neuronal cell body
0.46	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0120038	plasma membrane bounded cell projection part
0.44	GO:0005794	Golgi apparatus
0.44	GO:0005886	plasma membrane

sp|P40753|ANFB_MOUSE
Natriuretic peptides B
Search

0.94	Brain natriuretic peptide

0.81	GO:0050880	regulation of blood vessel size
0.76	GO:0010469	regulation of receptor activity
0.63	GO:0003299	muscle hypertrophy in response to stress
0.63	GO:0014887	cardiac muscle adaptation
0.63	GO:0003300	cardiac muscle hypertrophy
0.57	GO:0007168	receptor guanylyl cyclase signaling pathway
0.53	GO:0006182	cGMP biosynthetic process
0.51	GO:1903816	positive regulation of collecting lymphatic vessel constriction
0.50	GO:0035810	positive regulation of urine volume
0.49	GO:0003298	physiological muscle hypertrophy

0.79	GO:0005179	hormone activity
0.47	GO:0051428	peptide hormone receptor binding
0.37	GO:0090729	toxin activity

0.66	GO:0005576	extracellular region
0.44	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0043234	protein complex
0.39	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P40764|DLX2_MOUSE
Homeobox protein DLX-2
Search

DLX2

0.91	Homeobox protein DLX-2

0.65	GO:0021893	cerebral cortex GABAergic interneuron fate commitment
0.65	GO:1902871	positive regulation of amacrine cell differentiation
0.64	GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment
0.64	GO:0048755	branching morphogenesis of a nerve
0.63	GO:0048715	negative regulation of oligodendrocyte differentiation
0.63	GO:0046533	negative regulation of photoreceptor cell differentiation
0.62	GO:0021544	subpallium development
0.61	GO:0021772	olfactory bulb development
0.61	GO:0009954	proximal/distal pattern formation
0.61	GO:0045746	negative regulation of Notch signaling pathway

0.64	GO:0043565	sequence-specific DNA binding
0.57	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.57	GO:0003727	single-stranded RNA binding
0.56	GO:0001012	RNA polymerase II regulatory region DNA binding
0.55	GO:0003682	chromatin binding
0.53	GO:0003690	double-stranded DNA binding
0.36	GO:0005515	protein binding

0.61

GO:0005634

nucleus

sp|P40935|PNMT_MOUSE
Phenylethanolamine N-methyltransferase
Search

PNMT

0.92	Phenylethanolamine N-methyltransferase

0.63	GO:0032259	methylation
0.45	GO:0042418	epinephrine biosynthetic process
0.38	GO:0010243	response to organonitrogen compound
0.37	GO:0031100	animal organ regeneration
0.37	GO:0035900	response to isolation stress
0.37	GO:0035902	response to immobilization stress
0.37	GO:0045472	response to ether
0.37	GO:0042493	response to drug
0.37	GO:0042415	norepinephrine metabolic process
0.36	GO:0030325	adrenal gland development

0.63	GO:0008168	methyltransferase activity
0.32	GO:0005515	protein binding

0.44	GO:0005829	cytosol
0.37	GO:0043196	varicosity
0.36	GO:0043204	perikaryon
0.36	GO:0043195	terminal bouton
0.36	GO:0030425	dendrite
0.33	GO:0005634	nucleus

0.63

GO:0008168

sp|P40936|INMT_MOUSE
Indolethylamine N-methyltransferase
Search

NNMT

0.89	Indolethylamine N-methyltransferase

0.63	GO:0032259	methylation
0.39	GO:0042418	epinephrine biosynthetic process
0.39	GO:0031100	animal organ regeneration
0.38	GO:0009308	amine metabolic process
0.38	GO:0042221	response to chemical
0.35	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway
0.34	GO:0035900	response to isolation stress
0.34	GO:0035902	response to immobilization stress
0.34	GO:0042415	norepinephrine metabolic process
0.34	GO:0030325	adrenal gland development

0.63	GO:0008168	methyltransferase activity
0.33	GO:0005515	protein binding

0.48	GO:0005829	cytosol
0.34	GO:0043196	varicosity
0.34	GO:0043204	perikaryon
0.34	GO:0043195	terminal bouton
0.33	GO:0030425	dendrite
0.32	GO:0005634	nucleus

0.63

GO:0008168

sp|P41047|TNFL6_MOUSE
Tumor necrosis factor ligand superfamily member 6
Search

FASLG

0.97	Tumor necrosis factor ligand superfamily member 6

0.73	GO:0006955	immune response
0.71	GO:0006915	apoptotic process
0.69	GO:0010469	regulation of receptor activity
0.67	GO:1903514	release of sequestered calcium ion into cytosol by endoplasmic reticulum
0.67	GO:0097527	necroptotic signaling pathway
0.66	GO:2000353	positive regulation of endothelial cell apoptotic process
0.66	GO:0046666	retinal cell programmed cell death
0.63	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.62	GO:0016525	negative regulation of angiogenesis
0.62	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling

0.83	GO:0005164	tumor necrosis factor receptor binding
0.73	GO:0005125	cytokine activity
0.45	GO:0005123	death receptor binding
0.34	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.33	GO:0005199	structural constituent of cell wall
0.33	GO:0008270	zinc ion binding
0.32	GO:0003677	DNA binding

0.67	GO:0005615	extracellular space
0.61	GO:1903561	extracellular vesicle
0.60	GO:0009897	external side of plasma membrane
0.49	GO:0005634	nucleus
0.49	GO:0043202	lysosomal lumen
0.49	GO:0060205	cytoplasmic vesicle lumen
0.44	GO:0005901	caveola
0.42	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005887	integral component of plasma membrane
0.33	GO:0034708	methyltransferase complex

sp|P41105|RL28_MOUSE
60S ribosomal protein L28
Search

RPL28

0.73	Ribosomal protein L28

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.44	GO:1903146	regulation of autophagy of mitochondrion
0.44	GO:1903955	positive regulation of protein targeting to mitochondrion
0.37	GO:0043009	chordate embryonic development
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.63	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding
0.34	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0016787	hydrolase activity
0.33	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.45	GO:0044445	cytosolic part
0.43	GO:0030425	dendrite
0.43	GO:0044297	cell body
0.42	GO:0036464	cytoplasmic ribonucleoprotein granule
0.40	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.33	GO:0099512	supramolecular fiber
0.33	GO:0015630	microtubule cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016787

sp|P41133|ID3_MOUSE
DNA-binding protein inhibitor ID-3
Search

ID3

0.97	DNA-binding protein inhibitor ID-3-A

0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.65	GO:0072750	cellular response to leptomycin B
0.62	GO:0045667	regulation of osteoblast differentiation
0.62	GO:0045662	negative regulation of myoblast differentiation
0.61	GO:0030903	notochord development
0.61	GO:0048511	rhythmic process
0.60	GO:0030279	negative regulation of ossification
0.60	GO:0001656	metanephros development
0.59	GO:0043433	negative regulation of DNA binding transcription factor activity
0.59	GO:0042476	odontogenesis

0.68	GO:0046983	protein dimerization activity
0.66	GO:1901707	leptomycin B binding
0.56	GO:0008134	transcription factor binding
0.55	GO:0019904	protein domain specific binding
0.47	GO:0003700	DNA binding transcription factor activity
0.45	GO:0003677	DNA binding
0.36	GO:0003714	transcription corepressor activity
0.34	GO:0008113	peptide-methionine (S)-S-oxide reductase activity
0.34	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.33	GO:0043234	protein complex

0.34

EC:1.8.4 EC:1.8.4.11

GO:0008113

sp|P41136|ID2_MOUSE
DNA-binding protein inhibitor ID-2
Search

ID2

0.97	Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.59	GO:0061031	endodermal digestive tract morphogenesis
0.57	GO:0045578	negative regulation of B cell differentiation
0.57	GO:0045777	positive regulation of blood pressure
0.57	GO:0003166	bundle of His development
0.57	GO:0048557	embryonic digestive tract morphogenesis
0.57	GO:0090398	cellular senescence
0.57	GO:2000178	negative regulation of neural precursor cell proliferation
0.56	GO:0001966	thigmotaxis
0.56	GO:0071158	positive regulation of cell cycle arrest

0.68	GO:0046983	protein dimerization activity
0.55	GO:0044325	ion channel binding
0.47	GO:0003677	DNA binding
0.39	GO:0043425	bHLH transcription factor binding
0.34	GO:1901707	leptomycin B binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0019904	protein domain specific binding

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.44	GO:0043234	protein complex
0.34	GO:0000785	chromatin

sp|P41139|ID4_MOUSE
DNA-binding protein inhibitor ID-4
Search

ID4

0.92	DNA-binding protein inhibitor

0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.58	GO:0045667	regulation of osteoblast differentiation
0.58	GO:0048715	negative regulation of oligodendrocyte differentiation
0.58	GO:0061682	seminal vesicle morphogenesis
0.57	GO:0048710	regulation of astrocyte differentiation
0.57	GO:0007623	circadian rhythm
0.57	GO:0014003	oligodendrocyte development
0.57	GO:0060741	prostate gland stromal morphogenesis
0.56	GO:0045665	negative regulation of neuron differentiation
0.56	GO:0045598	regulation of fat cell differentiation

0.68	GO:0046983	protein dimerization activity
0.52	GO:0001085	RNA polymerase II transcription factor binding
0.44	GO:0003677	DNA binding
0.43	GO:0044325	ion channel binding
0.42	GO:0043621	protein self-association
0.38	GO:0043425	bHLH transcription factor binding
0.38	GO:0140110	transcription regulator activity
0.36	GO:0047485	protein N-terminus binding
0.36	GO:0070628	proteasome binding
0.36	GO:0008022	protein C-terminus binding

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.39	GO:0012505	endomembrane system
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:0043234	protein complex
0.37	GO:0044446	intracellular organelle part
0.35	GO:0015630	microtubule cytoskeleton
0.33	GO:0005694	chromosome

sp|P41149|MC5R_MOUSE
Melanocortin receptor 5
Search

MC5R

0.97	Melanocortin receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0019933	cAMP-mediated signaling
0.41	GO:0030819	positive regulation of cAMP biosynthetic process
0.40	GO:2000252	negative regulation of feeding behavior
0.40	GO:0097009	energy homeostasis
0.38	GO:0040008	regulation of growth
0.38	GO:0006112	energy reserve metabolic process

0.84	GO:0004977	melanocortin receptor activity
0.39	GO:0042562	hormone binding
0.33	GO:0005515	protein binding

0.55	GO:0005886	plasma membrane
0.36	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|P41155|TNFC_MOUSE
Lymphotoxin-beta
Search

LTB

0.95	Lymphotoxin-beta

0.74	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.69	GO:0045084	positive regulation of interleukin-12 biosynthetic process
0.67	GO:0048535	lymph node development
0.63	GO:0043588	skin development
0.45	GO:0010467	gene expression
0.37	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.36	GO:0007267	cell-cell signaling

0.84	GO:0005164	tumor necrosis factor receptor binding
0.79	GO:0005125	cytokine activity
0.41	GO:0043120	tumor necrosis factor binding

0.72	GO:0005615	extracellular space
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P41158|ELK4_MOUSE
ETS domain-containing protein Elk-4
Search

ELK4

0.97	ETS domain-containing protein Elk-4

0.59	GO:0070932	histone H3 deacetylation
0.57	GO:0000122	negative regulation of transcription by RNA polymerase II
0.56	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0030154	cell differentiation
0.36	GO:0006366	transcription by RNA polymerase II
0.35	GO:0001525	angiogenesis
0.35	GO:0042060	wound healing

0.63	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.57	GO:0001012	RNA polymerase II regulatory region DNA binding
0.57	GO:0003682	chromatin binding
0.54	GO:0003690	double-stranded DNA binding
0.36	GO:0003712	transcription cofactor activity
0.36	GO:0001047	core promoter binding
0.34	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.52	GO:0005829	cytosol
0.51	GO:0031974	membrane-enclosed lumen
0.46	GO:0044446	intracellular organelle part
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

sp|P41160|LEP_MOUSE
Leptin
Search

LEP

0.97

Leptin

0.76	GO:0010469	regulation of receptor activity
0.64	GO:1990051	activation of protein kinase C activity
0.64	GO:0032615	interleukin-12 production
0.63	GO:0072604	interleukin-6 secretion
0.63	GO:0032310	prostaglandin secretion
0.63	GO:0072606	interleukin-8 secretion
0.62	GO:0032868	response to insulin
0.62	GO:0032817	regulation of natural killer cell proliferation
0.61	GO:0090335	regulation of brown fat cell differentiation
0.61	GO:0032099	negative regulation of appetite

0.79	GO:0005179	hormone activity
0.49	GO:0051428	peptide hormone receptor binding
0.35	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.38	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P41163|ETV2_MOUSE
ETS translocation variant 2
Search

ETV2

0.97	LOW QUALITY PROTEIN: ETS translocation variant 2

0.60	GO:0060803	BMP signaling pathway involved in mesodermal cell fate specification
0.59	GO:2000382	positive regulation of mesoderm development
0.58	GO:0045603	positive regulation of endothelial cell differentiation
0.56	GO:0001824	blastocyst development
0.56	GO:0030099	myeloid cell differentiation
0.55	GO:0001890	placenta development
0.55	GO:0034101	erythrocyte homeostasis
0.55	GO:0048514	blood vessel morphogenesis
0.54	GO:0007219	Notch signaling pathway
0.52	GO:0045893	positive regulation of transcription, DNA-templated

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding
0.41	GO:0019904	protein domain specific binding
0.35	GO:0035259	glucocorticoid receptor binding
0.33	GO:0003723	RNA binding
0.33	GO:0004930	G-protein coupled receptor activity

0.61	GO:0005634	nucleus
0.39	GO:0005829	cytosol
0.39	GO:0043233	organelle lumen
0.36	GO:0044446	intracellular organelle part
0.36	GO:0005886	plasma membrane
0.35	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

sp|P41164|ETV1_MOUSE
ETS translocation variant 1
Search

ETV1

0.96	Ets transcription factor

0.85	GO:0048935	peripheral nervous system neuron development
0.75	GO:0006366	transcription by RNA polymerase II
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0007638	mechanosensory behavior
0.49	GO:0007517	muscle organ development
0.49	GO:0007411	axon guidance
0.48	GO:1902680	positive regulation of RNA biosynthetic process

0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.61

GO:0005634

nucleus

sp|P41183|BCL6_MOUSE
B-cell lymphoma 6 protein homolog
Search

BCL6

0.97	B-cell lymphoma 6 protein homolog

0.61	GO:0042092	type 2 immune response
0.61	GO:0032764	negative regulation of mast cell cytokine production
0.60	GO:0043380	regulation of memory T cell differentiation
0.60	GO:0048294	negative regulation of isotype switching to IgE isotypes
0.60	GO:0045591	positive regulation of regulatory T cell differentiation
0.59	GO:0045629	negative regulation of T-helper 2 cell differentiation
0.59	GO:0002467	germinal center formation
0.58	GO:0000060	protein import into nucleus, translocation
0.58	GO:2000773	negative regulation of cellular senescence
0.58	GO:0031065	positive regulation of histone deacetylation

0.58	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding
0.55	GO:0031490	chromatin DNA binding
0.54	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.52	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.51	GO:0042802	identical protein binding
0.34	GO:0005179	hormone activity
0.34	GO:0046872	metal ion binding

0.52	GO:0005657	replication fork
0.50	GO:0005794	Golgi apparatus
0.49	GO:0005654	nucleoplasm
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|P41209|CETN1_MOUSE
Centrin-1
Search

CETN1

0.90	Testicular tissue protein Li 37

0.46	GO:0007099	centriole replication
0.44	GO:0032465	regulation of cytokinesis
0.43	GO:0034605	cellular response to heat
0.42	GO:0007283	spermatogenesis
0.42	GO:0006289	nucleotide-excision repair
0.37	GO:0051301	cell division
0.36	GO:0055114	oxidation-reduction process
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.34	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle

0.70	GO:0005509	calcium ion binding
0.52	GO:0032795	heterotrimeric G-protein binding
0.48	GO:0031683	G-protein beta/gamma-subunit complex binding
0.45	GO:0008017	microtubule binding
0.44	GO:0016174	NAD(P)H oxidase activity
0.33	GO:0004386	helicase activity

0.55	GO:0005814	centriole
0.53	GO:0005813	centrosome
0.50	GO:0032391	photoreceptor connecting cilium
0.49	GO:0000922	spindle pole
0.48	GO:0071942	XPC complex
0.43	GO:0036064	ciliary basal body
0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol

0.44

EC:1.6.3.1

GO:0016174

sp|P41216|ACSL1_MOUSE
Long-chain-fatty-acid--CoA ligase 1
Search

ACSL1

0.85	Acyl-CoA synthetase long chain family member 1

0.66	GO:0044539	long-chain fatty acid import
0.66	GO:0033211	adiponectin-activated signaling pathway
0.60	GO:0001676	long-chain fatty acid metabolic process
0.59	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.51	GO:0008610	lipid biosynthetic process

0.61	GO:0004467	long-chain fatty acid-CoA ligase activity
0.37	GO:0102391	decanoate--CoA ligase activity

0.48	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.61

EC:6.2.1.3

GO:0004467

sp|P41230|KDM5C_MOUSE
Lysine-specific demethylase 5C
Search

KDM5C

0.96	Jumonji AT rich interactive domain 1D

0.58	GO:0034720	histone H3-K4 demethylation
0.53	GO:0032259	methylation
0.48	GO:0045892	negative regulation of transcription, DNA-templated
0.40	GO:0060765	regulation of androgen receptor signaling pathway
0.40	GO:0002457	T cell antigen processing and presentation
0.39	GO:0043524	negative regulation of neuron apoptotic process
0.38	GO:0009636	response to toxic substance
0.38	GO:0048511	rhythmic process
0.36	GO:0055114	oxidation-reduction process
0.36	GO:0006351	transcription, DNA-templated

0.58	GO:0032453	histone demethylase activity (H3-K4 specific)
0.54	GO:0003677	DNA binding
0.54	GO:0046872	metal ion binding
0.53	GO:0008168	methyltransferase activity
0.40	GO:0050681	androgen receptor binding
0.39	GO:0051213	dioxygenase activity
0.37	GO:0001085	RNA polymerase II transcription factor binding
0.35	GO:0042802	identical protein binding
0.35	GO:0005086	ARF guanyl-nucleotide exchange factor activity

0.61	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.46	GO:0005829	cytosol
0.42	GO:0044446	intracellular organelle part
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.53

GO:0008168

sp|P41233|ABCA1_MOUSE
ATP-binding cassette sub-family A member 1
Search

ABCA1

0.91	ATP-binding cassette transporter 1

0.63	GO:0060155	platelet dense granule organization
0.63	GO:0038027	apolipoprotein A-I-mediated signaling pathway
0.62	GO:0010874	regulation of cholesterol efflux
0.62	GO:0050702	interleukin-1 beta secretion
0.62	GO:0032489	regulation of Cdc42 protein signal transduction
0.62	GO:0034380	high-density lipoprotein particle assembly
0.62	GO:0034616	response to laminar fluid shear stress
0.61	GO:0033700	phospholipid efflux
0.61	GO:0055091	phospholipid homeostasis
0.61	GO:0071404	cellular response to low-density lipoprotein particle stimulus

0.65	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.64	GO:0090556	phosphatidylserine-translocating ATPase activity
0.64	GO:0034188	apolipoprotein A-I receptor activity
0.63	GO:0090554	phosphatidylcholine-translocating ATPase activity
0.63	GO:0034186	apolipoprotein A-I binding
0.60	GO:0017127	cholesterol transporter activity
0.59	GO:0051117	ATPase binding
0.58	GO:0019905	syntaxin binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding

0.58	GO:0045335	phagocytic vesicle
0.56	GO:0098857	membrane microdomain
0.56	GO:0009897	external side of plasma membrane
0.55	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005794	Golgi apparatus
0.49	GO:0005887	integral component of plasma membrane
0.41	GO:0034364	high-density lipoprotein particle
0.35	GO:0016323	basolateral plasma membrane
0.35	GO:0016324	apical plasma membrane
0.34	GO:0005789	endoplasmic reticulum membrane

sp|P41234|ABCA2_MOUSE
ATP-binding cassette sub-family A member 2
Search

ABCA2

0.94	ATP-binding cassette sub-family A member 2

0.60	GO:0032380	regulation of intracellular sterol transport
0.58	GO:0070723	response to cholesterol
0.58	GO:0032374	regulation of cholesterol transport
0.57	GO:0042632	cholesterol homeostasis
0.55	GO:0055085	transmembrane transport
0.54	GO:0048545	response to steroid hormone
0.50	GO:0006357	regulation of transcription by RNA polymerase II
0.44	GO:0006869	lipid transport
0.35	GO:0042493	response to drug
0.35	GO:0006629	lipid metabolic process

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0005764	lysosome
0.52	GO:0005768	endosome
0.41	GO:0098852	lytic vacuole membrane
0.41	GO:0005815	microtubule organizing center
0.40	GO:0044433	cytoplasmic vesicle part
0.35	GO:0043190	ATP-binding cassette (ABC) transporter complex

sp|P41241|CSK_MOUSE
Tyrosine-protein kinase CSK
Search

CSK

0.59	Tyrosine-protein kinase

0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.57	GO:0042997	negative regulation of Golgi to plasma membrane protein transport
0.51	GO:0042127	regulation of cell proliferation
0.49	GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway
0.46	GO:0034332	adherens junction organization
0.45	GO:0060027	convergent extension involved in gastrulation
0.45	GO:0046777	protein autophosphorylation
0.44	GO:0001817	regulation of cytokine production
0.44	GO:0007417	central nervous system development
0.44	GO:0045087	innate immune response

0.79	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.55	GO:0034236	protein kinase A catalytic subunit binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0042802	identical protein binding
0.42	GO:0005102	receptor binding
0.35	GO:0070064	proline-rich region binding
0.35	GO:0019903	protein phosphatase binding
0.35	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

0.49	GO:0005911	cell-cell junction
0.44	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.35	GO:0098857	membrane microdomain
0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.79

GO:0004715

sp|P41242|MATK_MOUSE
Megakaryocyte-associated tyrosine-protein kinase
Search

MATK

0.58	Megakaryocyte-associated tyrosine-protein kinase

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.47	GO:0042127	regulation of cell proliferation
0.46	GO:0046777	protein autophosphorylation
0.46	GO:0030154	cell differentiation
0.45	GO:0045087	innate immune response
0.45	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.44	GO:0034334	adherens junction maintenance
0.43	GO:0010669	epithelial structure maintenance
0.43	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.42	GO:0048167	regulation of synaptic plasticity

0.80	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0005102	receptor binding
0.33	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway
0.32	GO:0008270	zinc ion binding
0.31	GO:0003676	nucleic acid binding

0.45	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.35	GO:0005911	cell-cell junction
0.35	GO:0005856	cytoskeleton
0.34	GO:0005737	cytoplasm
0.32	GO:0005887	integral component of plasma membrane

0.80

GO:0004715

sp|P41245|MMP9_MOUSE
Matrix metalloproteinase-9
Search

0.67	Matrix metalloproteinase

0.75	GO:0030574	collagen catabolic process
0.70	GO:0050900	leukocyte migration
0.70	GO:0001503	ossification
0.62	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
0.62	GO:1900122	positive regulation of receptor binding
0.62	GO:0051549	positive regulation of keratinocyte migration
0.61	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.61	GO:0006508	proteolysis
0.61	GO:0007566	embryo implantation
0.60	GO:0090200	positive regulation of release of cytochrome c from mitochondria

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.52	GO:0042802	identical protein binding
0.39	GO:0004252	serine-type endopeptidase activity
0.39	GO:0001968	fibronectin binding
0.38	GO:0032403	protein complex binding

0.74	GO:0031012	extracellular matrix
0.53	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.36	GO:1904724	tertiary granule lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0030017	sarcomere
0.35	GO:0043234	protein complex
0.33	GO:0005739	mitochondrion
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.70

GO:0004222

sp|P41251|NRAM1_MOUSE
Natural resistance-associated macrophage protein 1
Search

SLC11A1

0.96	Natural resistance-associated macrophages protein 1

0.66	GO:0030001	metal ion transport
0.59	GO:0045342	MHC class II biosynthetic process
0.59	GO:0032632	interleukin-3 production
0.58	GO:0002309	T cell proliferation involved in immune response
0.58	GO:0006876	cellular cadmium ion homeostasis
0.58	GO:0002606	positive regulation of dendritic cell antigen processing and presentation
0.57	GO:0032623	interleukin-2 production
0.57	GO:0060586	multicellular organismal iron ion homeostasis
0.57	GO:0002369	T cell cytokine production
0.57	GO:0043091	L-arginine import

0.69	GO:0046873	metal ion transmembrane transporter activity
0.50	GO:0015491	cation:cation antiporter activity
0.49	GO:0042803	protein homodimerization activity
0.49	GO:0015299	solute:proton antiporter activity
0.34	GO:0072509	divalent inorganic cation transmembrane transporter activity
0.33	GO:0016791	phosphatase activity

0.57	GO:0070821	tertiary granule membrane
0.56	GO:0030670	phagocytic vesicle membrane
0.52	GO:0005770	late endosome
0.52	GO:0005764	lysosome
0.51	GO:0010008	endosome membrane
0.41	GO:0005886	plasma membrane
0.36	GO:0009986	cell surface
0.36	GO:0101003	ficolin-1-rich granule membrane
0.34	GO:0005635	nuclear envelope
0.30	GO:0016021	integral component of membrane

0.33

EC:3.1.3 EC:3.1.3.41

GO:0016791

sp|P41272|CD27_MOUSE
CD27 antigen
Search

sp|P41274|TNFL9_MOUSE
Tumor necrosis factor ligand superfamily member 9
Search

TNFSF9

0.85	Tumor necrosis factor ligand superfamily member 9

0.87	GO:0045583	regulation of cytotoxic T cell differentiation
0.85	GO:0042104	positive regulation of activated T cell proliferation
0.84	GO:0043011	myeloid dendritic cell differentiation
0.83	GO:0032735	positive regulation of interleukin-12 production
0.82	GO:0045582	positive regulation of T cell differentiation
0.82	GO:0032729	positive regulation of interferon-gamma production
0.81	GO:0032755	positive regulation of interleukin-6 production
0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.64	GO:0007267	cell-cell signaling

0.83	GO:0005164	tumor necrosis factor receptor binding
0.80	GO:0005125	cytokine activity

0.72	GO:0005615	extracellular space
0.56	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P41317|MBL2_MOUSE
Mannose-binding protein C
Search

MBL2

0.87	Pulmonary surfactant-associated protein A

0.83	GO:0001867	complement activation, lectin pathway
0.54	GO:0044130	negative regulation of growth of symbiont in host
0.53	GO:0050830	defense response to Gram-positive bacterium
0.52	GO:0048525	negative regulation of viral process
0.51	GO:0006958	complement activation, classical pathway
0.49	GO:0051873	killing by host of symbiont cells
0.48	GO:0050766	positive regulation of phagocytosis
0.42	GO:0007155	cell adhesion
0.38	GO:0070207	protein homotrimerization
0.37	GO:0045917	positive regulation of complement activation

0.81	GO:0005537	mannose binding
0.53	GO:0048306	calcium-dependent protein binding
0.47	GO:0005102	receptor binding
0.46	GO:0005509	calcium ion binding
0.44	GO:0005540	hyaluronic acid binding
0.41	GO:0005201	extracellular matrix structural constituent
0.37	GO:0002020	protease binding
0.37	GO:0070273	phosphatidylinositol-4-phosphate binding
0.36	GO:0043621	protein self-association
0.35	GO:0005534	galactose binding

0.71	GO:0005581	collagen trimer
0.50	GO:0005576	extracellular region
0.34	GO:0009986	cell surface
0.33	GO:0019867	outer membrane
0.33	GO:0005887	integral component of plasma membrane
0.32	GO:0031594	neuromuscular junction
0.32	GO:0099081	supramolecular polymer

0.34

GO:0004252

sp|P41438|S19A1_MOUSE
Folate transporter 1
Search

SLC19A1

0.96	Solute carrier family 19 (Folate transporter), member 1

0.85	GO:0051958	methotrexate transport
0.84	GO:0015884	folic acid transport
0.81	GO:0035461	vitamin transmembrane transport
0.66	GO:0098838	reduced folate transmembrane transport
0.39	GO:0045117	azole transport
0.39	GO:0072531	pyrimidine-containing compound transmembrane transport
0.38	GO:0072348	sulfur compound transport
0.38	GO:0006855	drug transmembrane transport

0.85	GO:0015350	methotrexate transmembrane transporter activity
0.85	GO:0008517	folic acid transmembrane transporter activity
0.71	GO:0008518	reduced folate carrier activity
0.52	GO:0005542	folic acid binding
0.39	GO:0015234	thiamine transmembrane transporter activity

0.64	GO:0005887	integral component of plasma membrane
0.58	GO:0016323	basolateral plasma membrane
0.57	GO:0016324	apical plasma membrane

sp|P41539|TKN1_MOUSE
Protachykinin-1
Search

0.73	Tachykinin precursor 1

0.85	GO:0007217	tachykinin receptor signaling pathway
0.50	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.49	GO:0006954	inflammatory response
0.49	GO:1990090	cellular response to nerve growth factor stimulus
0.48	GO:0048265	response to pain
0.48	GO:0019233	sensory perception of pain
0.43	GO:0007267	cell-cell signaling
0.43	GO:0007218	neuropeptide signaling pathway
0.30	GO:0050671	positive regulation of lymphocyte proliferation
0.30	GO:0051272	positive regulation of cellular component movement

0.41

GO:0005102

receptor binding

0.46	GO:0005576	extracellular region
0.46	GO:0043025	neuronal cell body
0.46	GO:0030424	axon
0.30	GO:0016020	membrane
0.30	GO:0071944	cell periphery

sp|P41588|VIPR2_MOUSE
Vasoactive intestinal polypeptide receptor 2
Search

VIPR2

0.95	Vasoactive intestinal polypeptide receptor

0.68	GO:0007166	cell surface receptor signaling pathway
0.68	GO:0007186	G-protein coupled receptor signaling pathway
0.41	GO:0007190	activation of adenylate cyclase activity
0.41	GO:0048662	negative regulation of smooth muscle cell proliferation
0.34	GO:0007267	cell-cell signaling

0.84

GO:0004999

vasoactive intestinal polypeptide receptor activity

0.50	GO:0005886	plasma membrane
0.36	GO:0043235	receptor complex
0.35	GO:0005929	cilium
0.30	GO:0044425	membrane part

sp|P41593|PTH1R_MOUSE
Parathyroid hormone/parathyroid hormone-related peptide receptor
Search

PTH1R

0.92	Parathyroid hormone 1 receptor a

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.59	GO:0002076	osteoblast development
0.59	GO:0045453	bone resorption
0.58	GO:0030282	bone mineralization
0.58	GO:0019933	cAMP-mediated signaling
0.57	GO:0002062	chondrocyte differentiation
0.55	GO:0048469	cell maturation
0.54	GO:0006874	cellular calcium ion homeostasis
0.54	GO:0008285	negative regulation of cell proliferation

0.86	GO:0004991	parathyroid hormone receptor activity
0.62	GO:0017046	peptide hormone binding
0.58	GO:0043621	protein self-association
0.53	GO:0042803	protein homodimerization activity
0.35	GO:0001653	peptide receptor activity

0.51	GO:0005886	plasma membrane
0.40	GO:0005903	brush border
0.40	GO:0045177	apical part of cell
0.39	GO:0043235	receptor complex
0.39	GO:0120038	plasma membrane bounded cell projection part
0.38	GO:0005622	intracellular
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|P41731|CD63_MOUSE
CD63 antigen
Search

CD63

0.55	Tetraspanin

0.43	GO:0035188	hatching
0.42	GO:0007166	cell surface receptor signaling pathway
0.42	GO:1900746	regulation of vascular endothelial growth factor signaling pathway
0.41	GO:0050931	pigment cell differentiation
0.41	GO:0045807	positive regulation of endocytosis
0.41	GO:0006461	protein complex assembly
0.41	GO:2001046	positive regulation of integrin-mediated signaling pathway
0.41	GO:0043482	cellular pigment accumulation
0.40	GO:0002090	regulation of receptor internalization
0.40	GO:0016477	cell migration

0.46	GO:0003823	antigen binding
0.45	GO:0005178	integrin binding

0.44	GO:0031982	vesicle
0.41	GO:0031226	intrinsic component of plasma membrane
0.40	GO:0005764	lysosome
0.39	GO:0043230	extracellular organelle
0.39	GO:0012505	endomembrane system
0.39	GO:0098852	lytic vacuole membrane
0.38	GO:0009986	cell surface
0.38	GO:0005615	extracellular space
0.34	GO:0005925	focal adhesion
0.30	GO:0016021	integral component of membrane

sp|P41778|PBX1_MOUSE
Pre-B-cell leukemia transcription factor 1
Search

PBX1

0.94	Pre-B-cell leukemia transcription factor 1

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.54	GO:0030325	adrenal gland development
0.54	GO:0048536	spleen development
0.53	GO:0001658	branching involved in ureteric bud morphogenesis
0.53	GO:0009954	proximal/distal pattern formation
0.53	GO:0048538	thymus development
0.53	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
0.53	GO:0035162	embryonic hemopoiesis

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0046982	protein heterodimerization activity
0.48	GO:0003690	double-stranded DNA binding
0.38	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.50	GO:0005667	transcription factor complex
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.38	GO:0005737	cytoplasm
0.34	GO:0030496	midbody
0.30	GO:0016020	membrane

sp|P41969|ELK1_MOUSE
ETS domain-containing protein Elk-1
Search

ELK1

0.84	ETS domain-containing protein Elk-1

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0006366	transcription by RNA polymerase II
0.53	GO:0051254	positive regulation of RNA metabolic process
0.53	GO:0010557	positive regulation of macromolecule biosynthetic process
0.53	GO:0031328	positive regulation of cellular biosynthetic process
0.45	GO:0030154	cell differentiation
0.45	GO:0071394	cellular response to testosterone stimulus
0.44	GO:0071480	cellular response to gamma radiation

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0001085	RNA polymerase II transcription factor binding
0.56	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0003690	double-stranded DNA binding
0.41	GO:0003682	chromatin binding
0.36	GO:0001106	RNA polymerase II transcription corepressor activity

0.61	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.43	GO:0043679	axon terminus
0.42	GO:0043025	neuronal cell body
0.42	GO:0030425	dendrite
0.37	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P41971|ELK3_MOUSE
ETS domain-containing protein Elk-3
Search

ELK3

0.97	ETS domain-containing protein Elk-3

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0001525	angiogenesis
0.55	GO:0042060	wound healing
0.52	GO:0006366	transcription by RNA polymerase II
0.52	GO:1902680	positive regulation of RNA biosynthetic process
0.51	GO:1902679	negative regulation of RNA biosynthetic process
0.45	GO:0030154	cell differentiation
0.33	GO:0007165	signal transduction

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003714	transcription corepressor activity
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.48	GO:0031974	membrane-enclosed lumen
0.45	GO:0005739	mitochondrion
0.44	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P42082|CD86_MOUSE
T-lymphocyte activation antigen CD86
Search

CD86

0.95	T-lymphocyte activation antigen CD86

0.49	GO:0034138	toll-like receptor 3 signaling pathway
0.49	GO:0042102	positive regulation of T cell proliferation
0.48	GO:0042113	B cell activation
0.48	GO:0071222	cellular response to lipopolysaccharide
0.46	GO:0051607	defense response to virus
0.45	GO:0002912	negative regulation of lymphocyte anergy
0.45	GO:0002665	negative regulation of T cell tolerance induction
0.44	GO:0002309	T cell proliferation involved in immune response
0.43	GO:0002667	regulation of T cell anergy
0.43	GO:0001878	response to yeast

0.39	GO:0005102	receptor binding
0.37	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.37	GO:0104005	hijacked molecular function
0.37	GO:0015026	coreceptor activity

0.58	GO:0070062	extracellular exosome
0.47	GO:0009897	external side of plasma membrane
0.39	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.37	EC:2.7.1.153	GO:0046934
0.37	KEGG:R04545	GO:0046934

sp|P42125|ECI1_MOUSE
Enoyl-CoA delta isomerase 1, mitochondrial
Search

ECI1

0.90	Enoyl-CoA delta isomerase 1, mitochondrial

0.51	GO:0006635	fatty acid beta-oxidation
0.32	GO:0007165	signal transduction

0.55	GO:0016853	isomerase activity
0.45	GO:0004300	enoyl-CoA hydratase activity
0.34	GO:0042802	identical protein binding
0.34	GO:0003723	RNA binding
0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005739	mitochondrion
0.43	GO:0019866	organelle inner membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.55

EC:5

GO:0016853

sp|P42128|FOXK1_MOUSE
Forkhead box protein K1
Search

FOXK1

0.97	Forkhead box protein K1

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.52	GO:0051254	positive regulation of RNA metabolic process
0.51	GO:0010557	positive regulation of macromolecule biosynthetic process
0.51	GO:0031328	positive regulation of cellular biosynthetic process
0.50	GO:0051253	negative regulation of RNA metabolic process
0.50	GO:0010558	negative regulation of macromolecule biosynthetic process
0.50	GO:0031327	negative regulation of cellular biosynthetic process
0.47	GO:0030154	cell differentiation

0.63	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding
0.36	GO:0000287	magnesium ion binding
0.35	GO:0005515	protein binding
0.33	GO:0002151	G-quadruplex RNA binding

0.60	GO:0005634	nucleus
0.35	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005737	cytoplasm
0.33	GO:0034708	methyltransferase complex
0.33	GO:0033202	DNA helicase complex
0.32	GO:0005694	chromosome
0.32	GO:1904949	ATPase complex
0.30	GO:0031224	intrinsic component of membrane

sp|P42208|SEPT2_MOUSE
Septin-2
Search

SEPT2

0.92	Putative septins p-loop gtpase

0.67	GO:0051301	cell division
0.67	GO:0007049	cell cycle
0.57	GO:0002036	regulation of L-glutamate transport
0.54	GO:0007224	smoothened signaling pathway
0.53	GO:0060271	cilium assembly
0.49	GO:0032880	regulation of protein localization
0.47	GO:0050790	regulation of catalytic activity
0.39	GO:0007283	spermatogenesis
0.37	GO:0030154	cell differentiation
0.36	GO:0007399	nervous system development

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0045296	cadherin binding
0.52	GO:0032947	protein complex scaffold activity
0.48	GO:0030234	enzyme regulator activity
0.36	GO:0042802	identical protein binding
0.34	GO:0003924	GTPase activity

0.57	GO:0097227	sperm annulus
0.56	GO:0060170	ciliary membrane
0.55	GO:0031105	septin complex
0.55	GO:0032391	photoreceptor connecting cilium
0.53	GO:0043209	myelin sheath
0.53	GO:0005930	axoneme
0.51	GO:0009986	cell surface
0.50	GO:0045202	synapse
0.44	GO:0005634	nucleus
0.41	GO:0030496	midbody

sp|P42209|SEPT1_MOUSE
Septin-1
Search

0.85

Septin-1

0.69	GO:0017157	regulation of exocytosis
0.56	GO:0007056	spindle assembly involved in female meiosis
0.56	GO:0051311	meiotic metaphase plate congression
0.39	GO:0051301	cell division
0.35	GO:0016080	synaptic vesicle targeting
0.35	GO:1902803	regulation of synaptic vesicle transport
0.34	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.34	GO:0098693	regulation of synaptic vesicle cycle
0.34	GO:0046928	regulation of neurotransmitter secretion
0.34	GO:0031398	positive regulation of protein ubiquitination

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0042802	identical protein binding
0.36	GO:0008832	dGTPase activity
0.34	GO:0046983	protein dimerization activity
0.34	GO:0003924	GTPase activity
0.34	GO:0019905	syntaxin binding
0.34	GO:0035091	phosphatidylinositol binding

0.69	GO:0008021	synaptic vesicle
0.54	GO:0072687	meiotic spindle
0.53	GO:0030496	midbody
0.47	GO:0043195	terminal bouton
0.44	GO:0005938	cell cortex
0.39	GO:0005886	plasma membrane
0.38	GO:0005815	microtubule organizing center
0.36	GO:0032156	septin cytoskeleton
0.35	GO:0097227	sperm annulus
0.34	GO:0097517	contractile actin filament bundle

0.36	EC:3.1.5.1	GO:0008832
0.36	KEGG:R01856	GO:0008832

sp|P42225|STAT1_MOUSE
Signal transducer and activator of transcription 1
Search

STAT1

0.70	Signal transducer and activator of transcription

0.60	GO:0060333	interferon-gamma-mediated signaling pathway
0.59	GO:0001937	negative regulation of endothelial cell proliferation
0.59	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.58	GO:0007259	JAK-STAT cascade
0.58	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.58	GO:0046725	negative regulation by virus of viral protein levels in host cell
0.57	GO:0016525	negative regulation of angiogenesis
0.57	GO:0071357	cellular response to type I interferon
0.57	GO:0010742	macrophage derived foam cell differentiation
0.57	GO:0006351	transcription, DNA-templated

0.63	GO:0004871	signal transducer activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0035035	histone acetyltransferase binding
0.55	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.54	GO:1990841	promoter-specific chromatin binding
0.54	GO:0070491	repressing transcription factor binding
0.53	GO:0035257	nuclear hormone receptor binding
0.53	GO:0005164	tumor necrosis factor receptor binding
0.52	GO:0045296	cadherin binding
0.51	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.51	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0070013	intracellular organelle lumen
0.48	GO:0000785	chromatin
0.46	GO:0005829	cytosol
0.43	GO:0043234	protein complex
0.40	GO:0030425	dendrite
0.40	GO:0030424	axon

sp|P42227|STAT3_MOUSE
Signal transducer and activator of transcription 3
Search

STAT3

0.69	Signal transducer and activator of transcription

0.61	GO:0007165	signal transduction
0.58	GO:1904685	positive regulation of metalloendopeptidase activity
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0006355	regulation of transcription, DNA-templated
0.57	GO:0072540	T-helper 17 cell lineage commitment
0.56	GO:0042755	eating behavior
0.56	GO:0048592	eye morphogenesis
0.56	GO:0060019	radial glial cell differentiation
0.56	GO:1905564	positive regulation of vascular endothelial cell proliferation
0.56	GO:2001223	negative regulation of neuron migration

0.64	GO:0004871	signal transducer activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0001103	RNA polymerase II repressing transcription factor binding
0.55	GO:0003677	DNA binding
0.53	GO:0019903	protein phosphatase binding
0.51	GO:0019901	protein kinase binding
0.51	GO:0003682	chromatin binding
0.50	GO:0001067	regulatory region nucleic acid binding
0.49	GO:0042803	protein homodimerization activity
0.39	GO:0031730	CCR5 chemokine receptor binding

0.61	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.48	GO:0005737	cytoplasm
0.48	GO:0000785	chromatin
0.46	GO:0070013	intracellular organelle lumen
0.41	GO:0005886	plasma membrane
0.35	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

sp|P42228|STAT4_MOUSE
Signal transducer and activator of transcription 4
Search

STAT4

0.69	Signal transducer and activator of transcription

0.75	GO:0019221	cytokine-mediated signaling pathway
0.71	GO:0045944	positive regulation of transcription by RNA polymerase II
0.55	GO:0006351	transcription, DNA-templated
0.45	GO:0007259	JAK-STAT cascade
0.43	GO:0001937	negative regulation of endothelial cell proliferation
0.43	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.43	GO:0071346	cellular response to interferon-gamma
0.43	GO:0072001	renal system development
0.43	GO:0010742	macrophage derived foam cell differentiation
0.43	GO:0071356	cellular response to tumor necrosis factor

0.63	GO:0004871	signal transducer activity
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.50	GO:0042802	identical protein binding
0.41	GO:0035035	histone acetyltransferase binding
0.41	GO:1990841	promoter-specific chromatin binding
0.41	GO:0070491	repressing transcription factor binding
0.41	GO:0001067	regulatory region nucleic acid binding
0.40	GO:0035257	nuclear hormone receptor binding
0.40	GO:0005164	tumor necrosis factor receptor binding

0.61	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:0000785	chromatin
0.38	GO:0030425	dendrite
0.38	GO:0030424	axon
0.36	GO:0043234	protein complex

sp|P42230|STA5A_MOUSE
Signal transducer and activator of transcription 5A
Search

STAT5A

0.70	Signal transducer and activator of transcription

0.86	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0008284	positive regulation of cell proliferation
0.56	GO:0010468	regulation of gene expression
0.56	GO:0046543	development of secondary female sexual characteristics
0.55	GO:0045647	negative regulation of erythrocyte differentiation
0.55	GO:0046544	development of secondary male sexual characteristics
0.55	GO:0001779	natural killer cell differentiation

0.64	GO:0004871	signal transducer activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.51	GO:0035259	glucocorticoid receptor binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0046983	protein dimerization activity
0.38	GO:0003682	chromatin binding
0.36	GO:0004713	protein tyrosine kinase activity

0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.44	GO:0070013	intracellular organelle lumen
0.40	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

0.36

GO:0004713

sp|P42232|STA5B_MOUSE
Signal transducer and activator of transcription 5B
Search

STAT5B

0.70	Signal transducer and activator of transcription

0.86	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0046543	development of secondary female sexual characteristics
0.56	GO:0008284	positive regulation of cell proliferation
0.56	GO:0046544	development of secondary male sexual characteristics
0.56	GO:0045647	negative regulation of erythrocyte differentiation
0.56	GO:0001779	natural killer cell differentiation

0.64	GO:0004871	signal transducer activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.52	GO:0035259	glucocorticoid receptor binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0046983	protein dimerization activity
0.39	GO:0003682	chromatin binding
0.35	GO:0004713	protein tyrosine kinase activity

0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.43	GO:0070013	intracellular organelle lumen
0.40	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

0.35

GO:0004713

sp|P42337|PK3CA_MOUSE
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Search

PIK3CA

0.95	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

0.83	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process
0.81	GO:0048015	phosphatidylinositol-mediated signaling
0.75	GO:0046854	phosphatidylinositol phosphorylation
0.59	GO:0044029	hypomethylation of CpG island
0.57	GO:2000653	regulation of genetic imprinting
0.57	GO:2000270	negative regulation of fibroblast apoptotic process
0.56	GO:2000811	negative regulation of anoikis
0.56	GO:0097009	energy homeostasis
0.55	GO:0060612	adipose tissue development
0.55	GO:0043491	protein kinase B signaling

0.84	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.56	GO:0043560	insulin receptor substrate binding
0.53	GO:0030295	protein kinase activator activity
0.52	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.51	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity
0.37	GO:0004674	protein serine/threonine kinase activity
0.36	GO:1902379	chemoattractant activity involved in axon guidance
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding

0.62	GO:0005943	phosphatidylinositol 3-kinase complex, class IA
0.53	GO:0030027	lamellipodium
0.45	GO:0005622	intracellular
0.39	GO:0005886	plasma membrane
0.35	GO:0090723	growth cone part
0.30	GO:0016021	integral component of membrane

0.84	EC:2.7.1.137	GO:0016303
0.84	KEGG:R03362	GO:0016303

sp|P42567|EPS15_MOUSE
Epidermal growth factor receptor substrate 15
Search

EPS15

0.91	Epidermal growth factor receptor pathway substrate 15

0.62	GO:0006895	Golgi to endosome transport
0.60	GO:0048268	clathrin coat assembly
0.54	GO:0019065	receptor-mediated endocytosis of virus by host cell
0.47	GO:0001921	positive regulation of receptor recycling
0.45	GO:0032456	endocytic recycling
0.43	GO:0042127	regulation of cell proliferation
0.39	GO:0016050	vesicle organization
0.37	GO:0048488	synaptic vesicle endocytosis
0.37	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.37	GO:0007173	epidermal growth factor receptor signaling pathway

0.69	GO:0005509	calcium ion binding
0.61	GO:0031593	polyubiquitin modification-dependent protein binding
0.59	GO:0045296	cadherin binding
0.55	GO:0042802	identical protein binding
0.39	GO:0017124	SH3 domain binding
0.35	GO:0051082	unfolded protein binding

0.62	GO:0016235	aggresome
0.62	GO:0060170	ciliary membrane
0.62	GO:0030122	AP-2 adaptor complex
0.52	GO:0005829	cytosol
0.46	GO:0009925	basal plasma membrane
0.45	GO:0043231	intracellular membrane-bounded organelle
0.45	GO:0016324	apical plasma membrane
0.44	GO:0005769	early endosome
0.39	GO:0010008	endosome membrane
0.36	GO:0045202	synapse

sp|P42580|NKX12_MOUSE
NK1 transcription factor-related protein 2
Search

NKX1-2

0.90	Homeobox protein slou

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.39	GO:0007275	multicellular organism development
0.35	GO:0007521	muscle cell fate determination
0.34	GO:0048332	mesoderm morphogenesis
0.34	GO:0001708	cell fate specification
0.33	GO:0048646	anatomical structure formation involved in morphogenesis
0.33	GO:1902679	negative regulation of RNA biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.35	GO:0005515	protein binding
0.34	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

EC:3.5.4.4

GO:0004000

sp|P42581|HMX3_MOUSE
Homeobox protein HMX3
Search

HMX3

0.95	Homeobox protein HMX3-A

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0050885	neuromuscular process controlling balance
0.56	GO:0007566	embryo implantation
0.56	GO:0010468	regulation of gene expression
0.56	GO:0042472	inner ear morphogenesis
0.56	GO:0060135	maternal process involved in female pregnancy
0.53	GO:0007399	nervous system development
0.53	GO:0060322	head development
0.42	GO:0030154	cell differentiation

0.64	GO:0043565	sequence-specific DNA binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.35	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P42582|NKX25_MOUSE
Homeobox protein Nkx-2.5
Search

NKX2-5

0.96	Cardiac homeobox transcription factor

0.81	GO:1903779	regulation of cardiac conduction
0.78	GO:0060048	cardiac muscle contraction
0.74	GO:0007507	heart development
0.66	GO:0006357	regulation of transcription by RNA polymerase II
0.65	GO:0060037	pharyngeal system development
0.64	GO:0048536	spleen development
0.64	GO:0014855	striated muscle cell proliferation
0.63	GO:0014706	striated muscle tissue development
0.63	GO:0010667	negative regulation of cardiac muscle cell apoptotic process
0.62	GO:0010832	negative regulation of myotube differentiation

0.64	GO:0043565	sequence-specific DNA binding
0.58	GO:0003700	DNA binding transcription factor activity
0.57	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.56	GO:0001012	RNA polymerase II regulatory region DNA binding
0.55	GO:0003682	chromatin binding
0.54	GO:0001104	RNA polymerase II transcription cofactor activity
0.53	GO:0003690	double-stranded DNA binding
0.52	GO:0008134	transcription factor binding
0.52	GO:0042803	protein homodimerization activity
0.52	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.54	GO:0005667	transcription factor complex
0.52	GO:0032993	protein-DNA complex
0.45	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|P42586|NKX22_MOUSE
Homeobox protein Nkx-2.2
Search

NKX2-2

0.93	Homeobox protein Nkx-2.2

0.61	GO:0003327	type B pancreatic cell fate commitment
0.61	GO:0060580	ventral spinal cord interneuron fate determination
0.61	GO:0021530	spinal cord oligodendrocyte cell fate specification
0.60	GO:0003326	pancreatic A cell fate commitment
0.60	GO:0003329	pancreatic PP cell fate commitment
0.58	GO:0048714	positive regulation of oligodendrocyte differentiation
0.58	GO:0003323	type B pancreatic cell development
0.58	GO:0021782	glial cell development
0.57	GO:0048708	astrocyte differentiation
0.57	GO:0021522	spinal cord motor neuron differentiation

0.64	GO:0043565	sequence-specific DNA binding
0.53	GO:0003713	transcription coactivator activity
0.52	GO:0003682	chromatin binding
0.52	GO:0044212	transcription regulatory region DNA binding
0.51	GO:0008134	transcription factor binding
0.50	GO:0003690	double-stranded DNA binding
0.46	GO:0003700	DNA binding transcription factor activity
0.33	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.5.4.4

GO:0004000

sp|P42669|PURA_MOUSE
Transcriptional activator protein Pur-alpha
Search

PURA

0.95	Transcriptional activator protein Pur-alpha

0.72	GO:0030154	cell differentiation
0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.69	GO:0042127	regulation of cell proliferation
0.57	GO:0008283	cell proliferation
0.51	GO:0006268	DNA unwinding involved in DNA replication
0.50	GO:0017148	negative regulation of translation
0.49	GO:0007399	nervous system development
0.47	GO:0048522	positive regulation of cellular process
0.40	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0006915	apoptotic process

0.61	GO:0003700	DNA binding transcription factor activity
0.57	GO:0032422	purine-rich negative regulatory element binding
0.57	GO:0003691	double-stranded telomeric DNA binding
0.56	GO:0046332	SMAD binding
0.55	GO:0003723	RNA binding
0.55	GO:0000900	translation repressor activity, nucleic acid binding
0.52	GO:0003697	single-stranded DNA binding
0.52	GO:0008134	transcription factor binding
0.40	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.33	GO:0016675	oxidoreductase activity, acting on a heme group of donors

0.59	GO:0005662	DNA replication factor A complex
0.51	GO:0043025	neuronal cell body
0.51	GO:0030425	dendrite
0.38	GO:0005737	cytoplasm
0.35	GO:0000784	nuclear chromosome, telomeric region
0.33	GO:0031967	organelle envelope
0.30	GO:0016020	membrane

0.33

EC:1.9

GO:0016675

sp|P42682|TXK_MOUSE
Tyrosine-protein kinase TXK
Search

TXK

0.58	Tyrosine-protein kinase

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.62	GO:0046777	protein autophosphorylation
0.59	GO:0050778	positive regulation of immune response
0.58	GO:0010543	regulation of platelet activation
0.57	GO:0060334	regulation of interferon-gamma-mediated signaling pathway
0.56	GO:0001961	positive regulation of cytokine-mediated signaling pathway
0.56	GO:0032729	positive regulation of interferon-gamma production
0.54	GO:0051173	positive regulation of nitrogen compound metabolic process
0.54	GO:0007229	integrin-mediated signaling pathway
0.54	GO:0010604	positive regulation of macromolecule metabolic process

0.80	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0005102	receptor binding

0.48	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.45	GO:0005856	cytoskeleton
0.44	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.36	GO:0005911	cell-cell junction
0.30	GO:0031224	intrinsic component of membrane

0.80

GO:0004715

sp|P42703|LIFR_MOUSE
Leukemia inhibitory factor receptor
Search

LIFR

0.95	Leukemia inhibitory factor receptor alpha

0.78	GO:0019221	cytokine-mediated signaling pathway
0.54	GO:0048861	leukemia inhibitory factor signaling pathway
0.49	GO:0008284	positive regulation of cell proliferation
0.39	GO:0010656	negative regulation of muscle cell apoptotic process
0.39	GO:0031100	animal organ regeneration
0.38	GO:0048812	neuron projection morphogenesis
0.37	GO:0014070	response to organic cyclic compound
0.36	GO:0001959	regulation of cytokine-mediated signaling pathway

0.80	GO:0004896	cytokine receptor activity
0.54	GO:0005127	ciliary neurotrophic factor receptor binding
0.50	GO:0019838	growth factor binding
0.38	GO:0019955	cytokine binding
0.37	GO:0046982	protein heterodimerization activity

0.48	GO:0043235	receptor complex
0.45	GO:0005615	extracellular space
0.41	GO:1903561	extracellular vesicle
0.38	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P42859|HD_MOUSE
Huntingtin
Search

HTT

0.91	Huntingtin

0.62	GO:1905335	regulation of aggrephagy
0.61	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
0.60	GO:0098596	imitative learning
0.60	GO:1904504	positive regulation of lipophagy
0.60	GO:0098598	learned vocalization behavior or vocal learning
0.60	GO:0031223	auditory behavior
0.59	GO:1903599	positive regulation of autophagy of mitochondrion
0.59	GO:0045724	positive regulation of cilium assembly
0.58	GO:0031648	protein destabilization
0.57	GO:0047496	vesicle transport along microtubule

0.60	GO:0034452	dynactin binding
0.60	GO:0005522	profilin binding
0.58	GO:0045505	dynein intermediate chain binding
0.57	GO:0002039	p53 binding
0.57	GO:0044325	ion channel binding
0.56	GO:0048487	beta-tubulin binding
0.54	GO:0019900	kinase binding
0.53	GO:0031072	heat shock protein binding
0.51	GO:0042802	identical protein binding
0.45	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.57	GO:0016234	inclusion body
0.56	GO:0005776	autophagosome
0.56	GO:0005814	centriole
0.55	GO:0030425	dendrite
0.55	GO:0005770	late endosome
0.55	GO:0030424	axon
0.54	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0030659	cytoplasmic vesicle membrane
0.50	GO:0005794	Golgi apparatus

sp|P42866|OPRM_MOUSE
Mu-type opioid receptor
Search

OPRM1

0.97	Mu opioid receptor variant

0.85	GO:0038003	opioid receptor signaling pathway
0.79	GO:0007218	neuropeptide signaling pathway
0.60	GO:0061358	negative regulation of Wnt protein secretion
0.57	GO:0019233	sensory perception of pain
0.55	GO:0071315	cellular response to morphine
0.54	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.53	GO:0048149	behavioral response to ethanol
0.52	GO:0050769	positive regulation of neurogenesis
0.51	GO:0007212	dopamine receptor signaling pathway
0.51	GO:0019933	cAMP-mediated signaling

0.86	GO:0004979	beta-endorphin receptor activity
0.58	GO:0001965	G-protein alpha-subunit binding
0.55	GO:0038047	morphine receptor activity
0.49	GO:0031681	G-protein beta-subunit binding
0.49	GO:0042923	neuropeptide binding
0.45	GO:0038046	enkephalin receptor activity
0.43	GO:0005245	voltage-gated calcium channel activity
0.39	GO:0031005	filamin binding
0.38	GO:0008022	protein C-terminus binding
0.37	GO:0019904	protein domain specific binding

0.46	GO:0043005	neuron projection
0.44	GO:0043204	perikaryon
0.42	GO:0120038	plasma membrane bounded cell projection part
0.42	GO:0005768	endosome
0.42	GO:0005887	integral component of plasma membrane
0.38	GO:0042383	sarcolemma
0.38	GO:0031256	leading edge membrane
0.38	GO:0005925	focal adhesion
0.38	GO:0098857	membrane microdomain
0.37	GO:0098794	postsynapse

sp|P42867|GPT_MOUSE
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
Search

DPAGT1

0.50	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase

0.83	GO:0006488	dolichol-linked oligosaccharide biosynthetic process
0.80	GO:0006487	protein N-linked glycosylation
0.50	GO:0046465	dolichyl diphosphate metabolic process
0.43	GO:0008654	phospholipid biosynthetic process
0.42	GO:0019348	dolichol metabolic process
0.38	GO:0006047	UDP-N-acetylglucosamine metabolic process
0.37	GO:0016094	polyprenol biosynthetic process
0.36	GO:0051259	protein oligomerization
0.32	GO:0006508	proteolysis

0.85	GO:0003975	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity
0.77	GO:0008963	phospho-N-acetylmuramoyl-pentapeptide-transferase activity
0.61	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity
0.37	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0008270	zinc ion binding

0.45	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0031012	extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:2.7.8.15

GO:0003975

sp|P42925|PXMP2_MOUSE
Peroxisomal membrane protein 2
Search

PXMP2

0.97	Peroxisomal membrane protein 2

0.36	GO:0046942	carboxylic acid transport
0.35	GO:0055085	transmembrane transport

0.38	GO:0015267	channel activity
0.36	GO:0005515	protein binding

0.60	GO:0005778	peroxisomal membrane
0.48	GO:0031301	integral component of organelle membrane
0.47	GO:0043234	protein complex
0.36	GO:0005739	mitochondrion

sp|P42932|TCPQ_MOUSE
T-complex protein 1 subunit theta
Search

CCT8

0.80	Chaperonin containing TCP-1 theta subunit

0.69	GO:0006457	protein folding
0.54	GO:1904869	regulation of protein localization to Cajal body
0.54	GO:1904851	positive regulation of establishment of protein localization to telomere
0.53	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.52	GO:0032212	positive regulation of telomere maintenance via telomerase
0.52	GO:0046931	pore complex assembly
0.52	GO:0007339	binding of sperm to zona pellucida
0.51	GO:1900182	positive regulation of protein localization to nucleus
0.49	GO:0050821	protein stabilization
0.49	GO:1901998	toxin transport

0.71	GO:0051082	unfolded protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0045296	cadherin binding
0.47	GO:0044183	protein binding involved in protein folding
0.33	GO:0042623	ATPase activity, coupled

0.55	GO:0005832	chaperonin-containing T-complex
0.53	GO:0002199	zona pellucida receptor complex
0.49	GO:0044297	cell body
0.49	GO:0005815	microtubule organizing center
0.49	GO:0045111	intermediate filament cytoskeleton
0.47	GO:0005874	microtubule
0.45	GO:0005654	nucleoplasm
0.38	GO:0005929	cilium
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen

sp|P43006|EAA2_MOUSE
Excitatory amino acid transporter 2
Search

SLC1A2

0.45	Amino acid transporter

0.58	GO:0070777	D-aspartate transport
0.57	GO:0098712	L-glutamate import across plasma membrane
0.55	GO:0070207	protein homotrimerization
0.55	GO:0046326	positive regulation of glucose import
0.55	GO:0007632	visual behavior
0.54	GO:0035264	multicellular organism growth
0.54	GO:0010259	multicellular organism aging
0.54	GO:0043200	response to amino acid
0.53	GO:0021537	telencephalon development
0.53	GO:0030534	adult behavior

0.72	GO:0015293	symporter activity
0.53	GO:0005313	L-glutamate transmembrane transporter activity
0.49	GO:0015081	sodium ion transmembrane transporter activity
0.47	GO:0022853	active ion transmembrane transporter activity
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.55	GO:0030673	axolemma
0.50	GO:0009986	cell surface
0.46	GO:0005887	integral component of plasma membrane
0.35	GO:0043198	dendritic shaft
0.35	GO:0042734	presynaptic membrane
0.35	GO:0043197	dendritic spine

sp|P43021|NODAL_MOUSE
Nodal
Search

NODAL

0.97	Nodal growth differentiation factor

0.76	GO:0010469	regulation of receptor activity
0.66	GO:0048382	mesendoderm development
0.65	GO:0033505	floor plate morphogenesis
0.65	GO:0060802	epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification
0.65	GO:0090010	transforming growth factor beta receptor signaling pathway involved in primitive streak formation
0.65	GO:0048322	axial mesodermal cell fate commitment
0.65	GO:0038107	nodal signaling pathway involved in determination of left/right asymmetry
0.64	GO:1901383	negative regulation of chorionic trophoblast cell proliferation
0.64	GO:0003140	determination of left/right asymmetry in lateral mesoderm
0.64	GO:0060460	left lung morphogenesis

0.78	GO:0008083	growth factor activity
0.65	GO:0070698	type I activin receptor binding
0.52	GO:0005160	transforming growth factor beta receptor binding
0.50	GO:0005125	cytokine activity
0.38	GO:0016015	morphogen activity

0.66

GO:0005576

extracellular region

sp|P43023|CX6A2_MOUSE
Cytochrome c oxidase subunit 6A2, mitochondrial
Search

COX6A2

0.81	Cytochrome c oxidase subunit 6A, mitochondrial

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.43	GO:0050790	regulation of catalytic activity
0.41	GO:0006119	oxidative phosphorylation
0.41	GO:0009060	aerobic respiration

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity
0.43	GO:0030234	enzyme regulator activity

0.84	GO:0005751	mitochondrial respiratory chain complex IV
0.35	GO:0043209	myelin sheath
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016676

sp|P43024|CX6A1_MOUSE
Cytochrome c oxidase subunit 6A1, mitochondrial
Search

COX6A1

0.81	Cytochrome c oxidase subunit 6A, mitochondrial

0.62	GO:1902600	hydrogen ion transmembrane transport
0.60	GO:0022900	electron transport chain
0.43	GO:0050790	regulation of catalytic activity
0.41	GO:0006119	oxidative phosphorylation
0.41	GO:0009060	aerobic respiration

0.64	GO:0015002	heme-copper terminal oxidase activity
0.64	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.61	GO:0009055	electron transfer activity
0.44	GO:0030234	enzyme regulator activity

0.84	GO:0005751	mitochondrial respiratory chain complex IV
0.37	GO:0043209	myelin sheath
0.30	GO:0016021	integral component of membrane

0.64

EC:1.9

GO:0016675

sp|P43025|TETN_MOUSE
Tetranectin
Search

CLEC3B

0.97	Tetranectin

0.70	GO:0030282	bone mineralization
0.65	GO:0071560	cellular response to transforming growth factor beta stimulus
0.57	GO:0010756	positive regulation of plasminogen activation
0.40	GO:0001501	skeletal system development
0.37	GO:0002576	platelet degranulation

0.75	GO:0036143	kringle domain binding
0.66	GO:0008201	heparin binding
0.60	GO:0030246	carbohydrate binding
0.57	GO:0005509	calcium ion binding

0.72	GO:0001652	granular component
0.60	GO:0005615	extracellular space
0.43	GO:0005737	cytoplasm
0.40	GO:0031012	extracellular matrix
0.39	GO:1903561	extracellular vesicle
0.37	GO:0031983	vesicle lumen
0.35	GO:0097708	intracellular vesicle
0.35	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

sp|P43027|GDF5_MOUSE
Growth/differentiation factor 5
Search

GDF5

0.97	Growth differentiation factor 5 preproprotein (Predicted)

0.74	GO:0010469	regulation of receptor activity
0.66	GO:0007184	SMAD protein import into nucleus
0.66	GO:0060591	chondroblast differentiation
0.66	GO:0032332	positive regulation of chondrocyte differentiation
0.65	GO:2001054	negative regulation of mesenchymal cell apoptotic process
0.64	GO:0032331	negative regulation of chondrocyte differentiation
0.64	GO:0060395	SMAD protein signal transduction
0.63	GO:0035137	hindlimb morphogenesis
0.63	GO:0035136	forelimb morphogenesis
0.63	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

0.77	GO:0008083	growth factor activity
0.64	GO:0036122	BMP binding
0.55	GO:0042802	identical protein binding
0.50	GO:0005160	transforming growth factor beta receptor binding
0.48	GO:0005125	cytokine activity
0.35	GO:0046983	protein dimerization activity

0.65	GO:0005576	extracellular region
0.34	GO:0005886	plasma membrane
0.33	GO:0005750	mitochondrial respiratory chain complex III
0.30	GO:0016021	integral component of membrane

sp|P43028|GDF6_MOUSE
Growth/differentiation factor 6
Search

GDF6

0.97	Growth differentiation factor 6

0.75	GO:0010469	regulation of receptor activity
0.64	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.63	GO:0060395	SMAD protein signal transduction
0.63	GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation
0.62	GO:0060389	pathway-restricted SMAD protein phosphorylation
0.61	GO:0032924	activin receptor signaling pathway
0.61	GO:0032332	positive regulation of chondrocyte differentiation
0.60	GO:0030509	BMP signaling pathway
0.58	GO:0001934	positive regulation of protein phosphorylation
0.54	GO:1900744	regulation of p38MAPK cascade

0.78	GO:0008083	growth factor activity
0.51	GO:0042802	identical protein binding
0.50	GO:0005160	transforming growth factor beta receptor binding
0.48	GO:0005125	cytokine activity
0.47	GO:0046983	protein dimerization activity
0.38	GO:0036122	BMP binding
0.32	GO:0003677	DNA binding

0.66	GO:0005576	extracellular region
0.34	GO:0005720	nuclear heterochromatin
0.33	GO:0005750	mitochondrial respiratory chain complex III
0.30	GO:0016021	integral component of membrane

sp|P43029|GDF7_MOUSE
Growth/differentiation factor 7
Search

GDF7

0.91	Growth differentiation factor 7

0.76	GO:0010469	regulation of receptor activity
0.65	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.64	GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation
0.64	GO:0060389	pathway-restricted SMAD protein phosphorylation
0.63	GO:0032924	activin receptor signaling pathway
0.61	GO:0030509	BMP signaling pathway
0.60	GO:2001051	positive regulation of tendon cell differentiation
0.60	GO:0021509	roof plate formation
0.59	GO:0001934	positive regulation of protein phosphorylation
0.59	GO:0060395	SMAD protein signal transduction

0.78	GO:0008083	growth factor activity
0.54	GO:0042803	protein homodimerization activity
0.54	GO:0005160	transforming growth factor beta receptor binding
0.52	GO:0005125	cytokine activity
0.32	GO:0003677	DNA binding

0.66	GO:0005576	extracellular region
0.34	GO:0005720	nuclear heterochromatin
0.34	GO:0005750	mitochondrial respiratory chain complex III
0.30	GO:0016021	integral component of membrane

sp|P43081|GUC1A_MOUSE
Guanylyl cyclase-activating protein 1
Search

GUCA1A

0.97	Guanylate cyclase activating protein 1

0.83	GO:0031284	positive regulation of guanylate cyclase activity
0.71	GO:0007601	visual perception
0.53	GO:0007602	phototransduction
0.40	GO:0071277	cellular response to calcium ion
0.36	GO:0022400	regulation of rhodopsin mediated signaling pathway

0.84	GO:0008048	calcium sensitive guanylate cyclase activator activity
0.70	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding

0.73	GO:0001750	photoreceptor outer segment
0.40	GO:0001917	photoreceptor inner segment
0.35	GO:0060170	ciliary membrane

sp|P43117|PF2R_MOUSE
Prostaglandin F2-alpha receptor
Search

PTGFR

0.97	Ovarian prostaglandin F receptor

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.65	GO:0071798	response to prostaglandin D
0.62	GO:0071379	cellular response to prostaglandin stimulus
0.61	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.60	GO:0032355	response to estradiol
0.58	GO:0032496	response to lipopolysaccharide
0.56	GO:0008284	positive regulation of cell proliferation
0.56	GO:0043066	negative regulation of apoptotic process
0.52	GO:0010628	positive regulation of gene expression
0.36	GO:0007567	parturition

0.85	GO:0004958	prostaglandin F receptor activity
0.54	GO:0004960	thromboxane receptor activity
0.51	GO:0004957	prostaglandin E receptor activity
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.49	GO:0005576	extracellular region
0.44	GO:0005886	plasma membrane
0.40	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.33

EC:1.2.1

GO:0016620

sp|P43120|HHEX_MOUSE
Hematopoietically-expressed homeobox protein Hhex
Search

HHEX

0.97	Hematopoietically-expressed homeobox protein Hhex

0.62	GO:0061011	hepatic duct development
0.62	GO:0060431	primary lung bud formation
0.62	GO:0061017	hepatoblast differentiation
0.61	GO:0061010	gall bladder development
0.61	GO:0022027	interkinetic nuclear migration
0.60	GO:0070365	hepatocyte differentiation
0.60	GO:0090009	primitive streak formation
0.60	GO:0048853	forebrain morphogenesis
0.59	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway
0.59	GO:0030878	thyroid gland development

0.63	GO:0043565	sequence-specific DNA binding
0.60	GO:0071837	HMG box domain binding
0.59	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.58	GO:0008190	eukaryotic initiation factor 4E binding
0.57	GO:0008301	DNA binding, bending
0.57	GO:0070491	repressing transcription factor binding
0.56	GO:0001012	RNA polymerase II regulatory region DNA binding
0.54	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0003682	chromatin binding
0.53	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.50	GO:0032993	protein-DNA complex
0.40	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle

sp|P43135|COT2_MOUSE
COUP transcription factor 2
Search

NR2F2

0.81	Nuclear receptor subfamily 2 group F member 1-A

0.80	GO:0030522	intracellular receptor signaling pathway
0.79	GO:0043401	steroid hormone mediated signaling pathway
0.71	GO:0060838	lymphatic endothelial cell fate commitment
0.68	GO:0060850	regulation of transcription involved in cell fate commitment
0.61	GO:0001568	blood vessel development
0.61	GO:0009956	radial pattern formation
0.60	GO:0000122	negative regulation of transcription by RNA polymerase II
0.60	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity
0.60	GO:0001937	negative regulation of endothelial cell proliferation
0.60	GO:0010596	negative regulation of endothelial cell migration

0.82	GO:0004879	nuclear receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0001972	retinoic acid binding
0.61	GO:0008270	zinc ion binding
0.54	GO:0042803	protein homodimerization activity
0.47	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.54	GO:0005829	cytosol
0.53	GO:0070013	intracellular organelle lumen
0.47	GO:0044446	intracellular organelle part

sp|P43136|NR2F6_MOUSE
Nuclear receptor subfamily 2 group F member 6
Search

NR2F6

0.83	Estrogen receptor

0.79	GO:0030522	intracellular receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.54	GO:0050965	detection of temperature stimulus involved in sensory perception of pain
0.53	GO:0043153	entrainment of circadian clock by photoperiod
0.49	GO:0048666	neuron development
0.47	GO:1902679	negative regulation of RNA biosynthetic process

0.82	GO:0004879	nuclear receptor activity
0.79	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.52	GO:0035326	enhancer binding
0.51	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.49	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0003690	double-stranded DNA binding
0.35	GO:0005515	protein binding
0.34	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005829	cytosol

sp|P43137|LIT1_MOUSE
Lithostathine-1
Search

0.97	Regenerating islet-derived protein 3-beta

0.63	GO:1904697	regulation of acinar cell proliferation
0.63	GO:1990867	response to gastrin
0.63	GO:1990864	response to growth hormone-releasing hormone
0.63	GO:1903492	response to acetylsalicylate
0.62	GO:0010469	regulation of receptor activity
0.62	GO:1990785	response to water-immersion restraint stress
0.61	GO:1904692	positive regulation of type B pancreatic cell proliferation
0.60	GO:0007494	midgut development
0.59	GO:0007399	nervous system development
0.59	GO:1990868	response to chemokine

0.64	GO:0008083	growth factor activity
0.57	GO:0030246	carbohydrate binding
0.55	GO:0019903	protein phosphatase binding
0.53	GO:0042802	identical protein binding
0.48	GO:0046983	protein dimerization activity
0.40	GO:0019838	growth factor binding

0.60	GO:0042588	zymogen granule
0.58	GO:0032809	neuronal cell body membrane
0.58	GO:0032590	dendrite membrane
0.56	GO:0045178	basal part of cell
0.56	GO:0005576	extracellular region
0.56	GO:0030426	growth cone
0.53	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0005829	cytosol
0.46	GO:0043234	protein complex
0.40	GO:0045177	apical part of cell

sp|P43142|GP182_MOUSE
G-protein coupled receptor 182
Search

GPR182

0.97	G-protein coupled receptor 182

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.45	GO:0035556	intracellular signal transduction
0.38	GO:0001666	response to hypoxia
0.36	GO:0007166	cell surface receptor signaling pathway

0.72	GO:0004930	G-protein coupled receptor activity
0.38	GO:0001653	peptide receptor activity

0.37	GO:0005622	intracellular
0.37	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P43241|CDX2_MOUSE
Homeobox protein CDX-2
Search

CDX2

0.87	Homeodomain transcription factor

0.67	GO:0007275	multicellular organism development
0.64	GO:0014807	regulation of somitogenesis
0.61	GO:0035019	somatic stem cell population maintenance
0.61	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.61	GO:0008333	endosome to lysosome transport
0.59	GO:0002065	columnar/cuboidal epithelial cell differentiation
0.58	GO:0000122	negative regulation of transcription by RNA polymerase II
0.57	GO:0045597	positive regulation of cell differentiation
0.56	GO:0003006	developmental process involved in reproduction
0.56	GO:0009653	anatomical structure morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.60	GO:0035326	enhancer binding
0.60	GO:0001012	RNA polymerase II regulatory region DNA binding
0.59	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.58	GO:0003714	transcription corepressor activity
0.56	GO:0003690	double-stranded DNA binding
0.42	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0003682	chromatin binding
0.35	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.58	GO:0017053	transcriptional repressor complex
0.56	GO:0000793	condensed chromosome
0.50	GO:0031974	membrane-enclosed lumen
0.46	GO:0043234	protein complex
0.45	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.35

EC:2.7.10.1

GO:0004714

sp|P43247|MSH2_MOUSE
DNA mismatch repair protein Msh2
Search

MSH2

0.64	LOW QUALITY PROTEIN: DNA mismatch repair protein Msh2

0.72	GO:0006298	mismatch repair
0.59	GO:0016446	somatic hypermutation of immunoglobulin genes
0.59	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response
0.58	GO:0051096	positive regulation of helicase activity
0.58	GO:0010165	response to X-ray
0.58	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.58	GO:0048298	positive regulation of isotype switching to IgA isotypes
0.58	GO:0002312	B cell activation involved in immune response
0.57	GO:0048304	positive regulation of isotype switching to IgG isotypes
0.57	GO:0010224	response to UV-B

0.73	GO:0030983	mismatched DNA binding
0.59	GO:0032405	MutLalpha complex binding
0.58	GO:0032357	oxidized purine DNA binding
0.58	GO:0000400	four-way junction DNA binding
0.55	GO:0019237	centromeric DNA binding
0.55	GO:0008022	protein C-terminus binding
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0019901	protein kinase binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding

0.81	GO:0032301	MutSalpha complex
0.60	GO:0032302	MutSbeta complex
0.37	GO:0000784	nuclear chromosome, telomeric region
0.34	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.45

GO:0016887

sp|P43252|PI2R_MOUSE
Prostacyclin receptor
Search

PTGIR

0.95	Prostacyclin receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.59	GO:0019933	cAMP-mediated signaling
0.58	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway
0.58	GO:0032496	response to lipopolysaccharide
0.57	GO:0048662	negative regulation of smooth muscle cell proliferation
0.50	GO:0071379	cellular response to prostaglandin stimulus
0.49	GO:0034695	response to prostaglandin E
0.48	GO:1901655	cellular response to ketone
0.47	GO:0097306	cellular response to alcohol
0.46	GO:0032570	response to progesterone

0.74	GO:0004954	prostanoid receptor activity
0.35	GO:0005085	guanyl-nucleotide exchange factor activity

0.48	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P43267|SOX15_MOUSE
Protein SOX-15
Search

SOX15

0.97	SRY-box containing gene 15

0.60	GO:0014718	positive regulation of satellite cell activation involved in skeletal muscle regeneration
0.60	GO:0048627	myoblast development
0.59	GO:0070318	positive regulation of G0 to G1 transition
0.58	GO:2000288	positive regulation of myoblast proliferation
0.57	GO:0043403	skeletal muscle tissue regeneration
0.56	GO:0045843	negative regulation of striated muscle tissue development
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.52	GO:0000122	negative regulation of transcription by RNA polymerase II
0.39	GO:0035293	chitin-based larval cuticle pattern formation
0.39	GO:0007367	segment polarity determination

0.55	GO:0003677	DNA binding
0.53	GO:0003682	chromatin binding
0.51	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.50	GO:0046982	protein heterodimerization activity
0.33	GO:0003723	RNA binding
0.33	GO:0008080	N-acetyltransferase activity
0.32	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.43	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008080

sp|P43274|H14_MOUSE
Histone H1.4
Search

0.97	Histone cluster 1 H1 family member e

0.79	GO:0006334	nucleosome assembly
0.57	GO:0098532	histone H3-K27 trimethylation
0.55	GO:0080182	histone H3-K4 trimethylation
0.54	GO:0016584	nucleosome positioning
0.54	GO:0000122	negative regulation of transcription by RNA polymerase II
0.47	GO:0071169	establishment of protein localization to chromatin
0.47	GO:0051574	positive regulation of histone H3-K9 methylation
0.45	GO:0030307	positive regulation of cell growth
0.44	GO:0050821	protein stabilization
0.42	GO:0048260	positive regulation of receptor-mediated endocytosis

0.66	GO:0031490	chromatin DNA binding
0.45	GO:0042826	histone deacetylase binding
0.42	GO:0032564	dATP binding
0.41	GO:0008201	heparin binding
0.39	GO:0016208	AMP binding
0.38	GO:0043531	ADP binding
0.37	GO:0003690	double-stranded DNA binding
0.37	GO:0005509	calcium ion binding
0.37	GO:0003723	RNA binding
0.36	GO:0032550	purine ribonucleoside binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.58	GO:0000791	euchromatin
0.55	GO:0031974	membrane-enclosed lumen
0.53	GO:0000792	heterochromatin
0.48	GO:0035327	transcriptionally active chromatin
0.41	GO:0031982	vesicle
0.40	GO:0009986	cell surface
0.38	GO:0043230	extracellular organelle
0.37	GO:0005615	extracellular space

sp|P43275|H11_MOUSE
Histone H1.1
Search

0.97	Histone cluster 1 H1 family member a

0.79	GO:0006334	nucleosome assembly
0.55	GO:0098532	histone H3-K27 trimethylation
0.53	GO:0080182	histone H3-K4 trimethylation
0.52	GO:0016584	nucleosome positioning
0.51	GO:0000122	negative regulation of transcription by RNA polymerase II
0.48	GO:0048260	positive regulation of receptor-mediated endocytosis
0.46	GO:0007283	spermatogenesis
0.43	GO:0071169	establishment of protein localization to chromatin
0.43	GO:0051574	positive regulation of histone H3-K9 methylation
0.42	GO:0030307	positive regulation of cell growth

0.65	GO:0031490	chromatin DNA binding
0.47	GO:0008201	heparin binding
0.42	GO:0042826	histone deacetylase binding
0.40	GO:0032564	dATP binding
0.38	GO:0016208	AMP binding
0.37	GO:0043531	ADP binding
0.36	GO:0003690	double-stranded DNA binding
0.36	GO:0005509	calcium ion binding
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.59	GO:0000791	euchromatin
0.54	GO:0031974	membrane-enclosed lumen
0.50	GO:0000792	heterochromatin
0.47	GO:0035327	transcriptionally active chromatin
0.45	GO:0009986	cell surface
0.44	GO:0031982	vesicle
0.36	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space

sp|P43276|H15_MOUSE
Histone H1.5
Search

0.97	Histone cluster 1 H1 family member b

0.79	GO:0006334	nucleosome assembly
0.54	GO:0098532	histone H3-K27 trimethylation
0.53	GO:0000122	negative regulation of transcription by RNA polymerase II
0.52	GO:0080182	histone H3-K4 trimethylation
0.51	GO:0016584	nucleosome positioning
0.50	GO:0071169	establishment of protein localization to chromatin
0.49	GO:0051574	positive regulation of histone H3-K9 methylation
0.47	GO:0030307	positive regulation of cell growth
0.46	GO:0050821	protein stabilization
0.40	GO:0048260	positive regulation of receptor-mediated endocytosis

0.64	GO:0031490	chromatin DNA binding
0.48	GO:0042826	histone deacetylase binding
0.42	GO:0032564	dATP binding
0.39	GO:0008201	heparin binding
0.39	GO:0016208	AMP binding
0.38	GO:0043531	ADP binding
0.37	GO:0003690	double-stranded DNA binding
0.37	GO:0003723	RNA binding
0.37	GO:0005509	calcium ion binding
0.36	GO:0032550	purine ribonucleoside binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.55	GO:0000792	heterochromatin
0.54	GO:0031974	membrane-enclosed lumen
0.53	GO:0000791	euchromatin
0.46	GO:0035327	transcriptionally active chromatin
0.40	GO:0031982	vesicle
0.39	GO:0043230	extracellular organelle
0.38	GO:0005615	extracellular space
0.38	GO:0009986	cell surface

sp|P43277|H13_MOUSE
Histone H1.3
Search

0.97	Histone cluster 1 H1 family member d

0.79	GO:0006334	nucleosome assembly
0.56	GO:0098532	histone H3-K27 trimethylation
0.55	GO:0080182	histone H3-K4 trimethylation
0.54	GO:0016584	nucleosome positioning
0.54	GO:0000122	negative regulation of transcription by RNA polymerase II
0.46	GO:0071169	establishment of protein localization to chromatin
0.46	GO:0051574	positive regulation of histone H3-K9 methylation
0.44	GO:0030307	positive regulation of cell growth
0.43	GO:0050821	protein stabilization
0.43	GO:0048260	positive regulation of receptor-mediated endocytosis

0.66	GO:0031490	chromatin DNA binding
0.45	GO:0042826	histone deacetylase binding
0.42	GO:0008201	heparin binding
0.39	GO:0032564	dATP binding
0.37	GO:0016208	AMP binding
0.36	GO:0043531	ADP binding
0.36	GO:0003723	RNA binding
0.36	GO:0003690	double-stranded DNA binding
0.36	GO:0005509	calcium ion binding
0.35	GO:0046982	protein heterodimerization activity

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.59	GO:0000791	euchromatin
0.55	GO:0031974	membrane-enclosed lumen
0.52	GO:0000792	heterochromatin
0.48	GO:0035327	transcriptionally active chromatin
0.41	GO:0031982	vesicle
0.40	GO:0009986	cell surface
0.37	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space

sp|P43300|EGR3_MOUSE
Early growth response protein 3
Search

EGR3

0.83	Early growth response protein 3

0.57	GO:0002042	cell migration involved in sprouting angiogenesis
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0035767	endothelial cell chemotaxis
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0001938	positive regulation of endothelial cell proliferation
0.55	GO:0035924	cellular response to vascular endothelial growth factor stimulus
0.54	GO:0044344	cellular response to fibroblast growth factor stimulus
0.52	GO:0043066	negative regulation of apoptotic process

0.54	GO:0003677	DNA binding
0.53	GO:0046872	metal ion binding
0.35	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.60

GO:0005634

nucleus

sp|P43345|TLX1_MOUSE
T-cell leukemia homeobox protein 1
Search

TLX1

0.95	T-cell leukemia homeobox protein 1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0006366	transcription by RNA polymerase II
0.52	GO:1902680	positive regulation of RNA biosynthetic process
0.48	GO:0002087	regulation of respiratory gaseous exchange by neurological system process
0.48	GO:0007585	respiratory gaseous exchange
0.47	GO:0048665	neuron fate specification
0.47	GO:0001764	neuron migration
0.46	GO:0007417	central nervous system development

0.64	GO:0043565	sequence-specific DNA binding
0.56	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding
0.37	GO:0005515	protein binding
0.33	GO:0005198	structural molecule activity

0.61	GO:0005634	nucleus
0.42	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part
0.34	GO:0045111	intermediate filament cytoskeleton
0.33	GO:0099512	supramolecular fiber

sp|P43346|DCK_MOUSE
Deoxycytidine kinase
Search

DCK

0.61	Deoxynucleoside kinase

0.63	GO:0009165	nucleotide biosynthetic process
0.52	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process
0.51	GO:0016310	phosphorylation
0.48	GO:0006220	pyrimidine nucleotide metabolic process
0.36	GO:0046092	deoxycytidine metabolic process
0.34	GO:0046053	dAMP metabolic process
0.34	GO:0043097	pyrimidine nucleoside salvage
0.34	GO:0072522	purine-containing compound biosynthetic process
0.33	GO:0046385	deoxyribose phosphate biosynthetic process
0.33	GO:0009127	purine nucleoside monophosphate biosynthetic process

0.77	GO:0019206	nucleoside kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0042803	protein homodimerization activity
0.36	GO:0032548	pyrimidine deoxyribonucleoside binding
0.33	GO:0000287	magnesium ion binding
0.32	GO:0046982	protein heterodimerization activity
0.32	GO:0003677	DNA binding

0.45	GO:0005634	nucleus
0.35	GO:0005829	cytosol
0.32	GO:0000786	nucleosome

sp|P43352|RAD52_MOUSE
DNA repair protein RAD52 homolog
Search

RAD52

0.94	DNA repair protein RAD52 homolog

0.85	GO:0045002	double-strand break repair via single-strand annealing
0.84	GO:0000730	DNA recombinase assembly
0.58	GO:2000819	regulation of nucleotide-excision repair
0.58	GO:0000729	DNA double-strand break processing
0.53	GO:0051260	protein homooligomerization
0.52	GO:0034599	cellular response to oxidative stress
0.34	GO:0007015	actin filament organization

0.51	GO:0042802	identical protein binding
0.51	GO:0003697	single-stranded DNA binding
0.35	GO:0003785	actin monomer binding
0.33	GO:0005509	calcium ion binding

0.60	GO:0005634	nucleus
0.50	GO:0032993	protein-DNA complex
0.44	GO:0043234	protein complex
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

sp|P43404|ZAP70_MOUSE
Tyrosine-protein kinase ZAP-70
Search

ZAP70

0.59	Tyrosine-protein kinase

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.61	GO:0035556	intracellular signal transduction
0.57	GO:0045059	positive thymic T cell selection
0.57	GO:0043366	beta selection
0.56	GO:0045582	positive regulation of T cell differentiation
0.56	GO:0046641	positive regulation of alpha-beta T cell proliferation
0.54	GO:0050850	positive regulation of calcium-mediated signaling
0.54	GO:0045060	negative thymic T cell selection
0.54	GO:0046637	regulation of alpha-beta T cell differentiation
0.54	GO:0046777	protein autophosphorylation

0.80	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.45	GO:0005102	receptor binding
0.39	GO:0001784	phosphotyrosine residue binding
0.39	GO:0042169	SH2 domain binding
0.39	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity
0.38	GO:0019902	phosphatase binding

0.57	GO:0042101	T cell receptor complex
0.53	GO:0001772	immunological synapse
0.52	GO:0098857	membrane microdomain
0.49	GO:0005911	cell-cell junction
0.48	GO:0005737	cytoplasm
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.39	GO:0019815	B cell receptor complex
0.36	GO:0097708	intracellular vesicle
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.80

GO:0004715

sp|P43406|ITAV_MOUSE
Integrin alpha-V
Search

ITGAV

0.89	Alpha v integrin subunit variant

0.78	GO:0007229	integrin-mediated signaling pathway
0.71	GO:0007155	cell adhesion
0.65	GO:2000536	negative regulation of entry of bacterium into host cell
0.64	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process
0.63	GO:0038027	apolipoprotein A-I-mediated signaling pathway
0.63	GO:0038044	transforming growth factor-beta secretion
0.62	GO:0050748	negative regulation of lipoprotein metabolic process
0.62	GO:0010745	negative regulation of macrophage derived foam cell differentiation
0.62	GO:0010888	negative regulation of lipid storage
0.61	GO:0032369	negative regulation of lipid transport

0.63	GO:1990430	extracellular matrix protein binding
0.63	GO:0038132	neuregulin binding
0.63	GO:0019960	C-X3-C chemokine binding
0.62	GO:0031994	insulin-like growth factor I binding
0.62	GO:0001968	fibronectin binding
0.61	GO:0001846	opsonin binding
0.61	GO:0017134	fibroblast growth factor binding
0.59	GO:0005080	protein kinase C binding
0.59	GO:0005178	integrin binding
0.59	GO:0050840	extracellular matrix binding

0.79	GO:0008305	integrin complex
0.64	GO:0035868	alphav-beta3 integrin-HMGB1 complex
0.63	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex
0.62	GO:0031258	lamellipodium membrane
0.62	GO:0031528	microvillus membrane
0.62	GO:0031527	filopodium membrane
0.59	GO:0032587	ruffle membrane
0.58	GO:0005925	focal adhesion
0.56	GO:0009897	external side of plasma membrane
0.50	GO:0005829	cytosol

sp|P43407|SDC2_MOUSE
Syndecan-2
Search

SDC2

0.83

Syndecan

0.55	GO:0048814	regulation of dendrite morphogenesis
0.48	GO:0016477	cell migration
0.46	GO:0048813	dendrite morphogenesis
0.43	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.42	GO:0070121	Kupffer's vesicle development
0.41	GO:0002040	sprouting angiogenesis
0.41	GO:0048565	digestive tract development
0.40	GO:0007507	heart development
0.39	GO:0097435	supramolecular fiber organization
0.37	GO:0042060	wound healing

0.57	GO:0030165	PDZ domain binding
0.51	GO:0042802	identical protein binding
0.34	GO:0070053	thrombospondin receptor activity
0.33	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding

0.51	GO:0031012	extracellular matrix
0.45	GO:0009986	cell surface
0.38	GO:0005796	Golgi lumen
0.35	GO:0043202	lysosomal lumen
0.35	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0043025	neuronal cell body
0.34	GO:0045202	synapse
0.33	GO:0005886	plasma membrane
0.33	GO:0005925	focal adhesion
0.30	GO:0016021	integral component of membrane

sp|P43430|MCPT8_MOUSE
Mast cell protease 8
Search

0.85	Natural killer cell protease 1

0.61	GO:0006508	proteolysis
0.55	GO:0008626	granzyme-mediated apoptotic signaling pathway
0.55	GO:0001909	leukocyte mediated cytotoxicity
0.53	GO:0002443	leukocyte mediated immunity
0.49	GO:0045087	innate immune response
0.48	GO:0042222	interleukin-1 biosynthetic process
0.47	GO:0034769	basement membrane disassembly
0.46	GO:0032611	interleukin-1 beta production
0.43	GO:0051873	killing by host of symbiont cells
0.41	GO:0050830	defense response to Gram-positive bacterium

0.69	GO:0004252	serine-type endopeptidase activity
0.39	GO:0008201	heparin binding
0.36	GO:0042277	peptide binding
0.34	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding

0.58	GO:0030141	secretory granule
0.45	GO:0005576	extracellular region
0.39	GO:0010494	cytoplasmic stress granule
0.35	GO:0005764	lysosome
0.35	GO:0005886	plasma membrane
0.34	GO:0060205	cytoplasmic vesicle lumen
0.34	GO:0005775	vacuolar lumen
0.34	GO:0005769	early endosome
0.34	GO:0009986	cell surface
0.33	GO:0005634	nucleus

0.69

GO:0004252

sp|P43431|IL12A_MOUSE
Interleukin-12 subunit alpha
Search

IL12A

0.97	Interleukin-12 subunit alpha

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.67	GO:0051135	positive regulation of NK T cell activation
0.67	GO:0002857	positive regulation of natural killer cell mediated immune response to tumor cell
0.67	GO:0002858	regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.67	GO:2000510	positive regulation of dendritic cell chemotaxis
0.66	GO:0034393	positive regulation of smooth muscle cell apoptotic process
0.66	GO:0001916	positive regulation of T cell mediated cytotoxicity
0.66	GO:0032700	negative regulation of interleukin-17 production
0.66	GO:0032816	positive regulation of natural killer cell activation

0.87	GO:0005143	interleukin-12 receptor binding
0.80	GO:0005125	cytokine activity
0.78	GO:0008083	growth factor activity
0.72	GO:0042163	interleukin-12 beta subunit binding
0.70	GO:0019975	interleukin-17 binding
0.58	GO:0046982	protein heterodimerization activity

0.73	GO:0005615	extracellular space
0.49	GO:0043234	protein complex
0.42	GO:0031904	endosome lumen
0.40	GO:0005788	endoplasmic reticulum lumen
0.39	GO:0005796	Golgi lumen
0.36	GO:0005770	late endosome

sp|P43432|IL12B_MOUSE
Interleukin-12 subunit beta
Search

IL12B

0.96	Interleukin-12 subunit beta

0.79	GO:0019221	cytokine-mediated signaling pathway
0.74	GO:0010469	regulation of receptor activity
0.65	GO:0010536	positive regulation of activation of Janus kinase activity
0.65	GO:0051140	regulation of NK T cell proliferation
0.65	GO:0032819	positive regulation of natural killer cell proliferation
0.65	GO:0051135	positive regulation of NK T cell activation
0.65	GO:0002857	positive regulation of natural killer cell mediated immune response to tumor cell
0.65	GO:0002858	regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.64	GO:0042104	positive regulation of activated T cell proliferation
0.64	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production

0.80	GO:0004896	cytokine receptor activity
0.79	GO:0005125	cytokine activity
0.68	GO:0042164	interleukin-12 alpha subunit binding
0.66	GO:0045519	interleukin-23 receptor binding
0.57	GO:0008083	growth factor activity
0.55	GO:0046982	protein heterodimerization activity
0.55	GO:0042802	identical protein binding
0.39	GO:0005143	interleukin-12 receptor binding

0.72	GO:0005615	extracellular space
0.47	GO:0043234	protein complex
0.40	GO:0005737	cytoplasm
0.37	GO:0097708	intracellular vesicle
0.36	GO:0012505	endomembrane system
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

sp|P43488|TNFL4_MOUSE
Tumor necrosis factor ligand superfamily member 4
Search

TNFSF4

0.97	Tumor necrosis factor ligand superfamily member 4

0.74	GO:0006955	immune response
0.73	GO:0032753	positive regulation of interleukin-4 production
0.71	GO:0032729	positive regulation of interferon-gamma production
0.70	GO:0032755	positive regulation of interleukin-6 production
0.69	GO:0001818	negative regulation of cytokine production
0.67	GO:0050727	regulation of inflammatory response
0.67	GO:0035714	cellular response to nitrogen dioxide
0.67	GO:0035783	CD4-positive, alpha-beta T cell costimulation
0.67	GO:2000571	regulation of interleukin-4-dependent isotype switching to IgE isotypes
0.67	GO:1900279	regulation of CD4-positive, alpha-beta T cell costimulation

0.84	GO:0005164	tumor necrosis factor receptor binding
0.58	GO:0005125	cytokine activity

0.63	GO:0005615	extracellular space
0.60	GO:0009986	cell surface
0.30	GO:0016020	membrane

sp|P43680|SOX18_MOUSE
Transcription factor SOX-18
Search

SOX18

0.86	SRY-box 18

0.82	GO:0060214	endocardium formation
0.80	GO:0060956	endocardial cell differentiation
0.80	GO:0048866	stem cell fate specification
0.80	GO:0060836	lymphatic endothelial cell differentiation
0.79	GO:0001946	lymphangiogenesis
0.78	GO:0042789	mRNA transcription by RNA polymerase II
0.78	GO:0043534	blood vessel endothelial cell migration
0.78	GO:0061028	establishment of endothelial barrier
0.76	GO:0001570	vasculogenesis
0.75	GO:0072091	regulation of stem cell proliferation

0.72	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.71	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.66	GO:0046982	protein heterodimerization activity

0.68	GO:0044798	nuclear transcription factor complex
0.67	GO:0000790	nuclear chromatin

sp|P43687|HMX2_MOUSE
Homeobox protein HMX2
Search

HMX2

0.80	Homeobox transcription factor

0.62	GO:0042472	inner ear morphogenesis
0.59	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0007420	brain development
0.54	GO:0008284	positive regulation of cell proliferation
0.46	GO:0048916	posterior lateral line development
0.38	GO:0030154	cell differentiation
0.38	GO:0050885	neuromuscular process controlling balance
0.37	GO:0007566	embryo implantation

0.64	GO:0043565	sequence-specific DNA binding
0.37	GO:0001012	RNA polymerase II regulatory region DNA binding
0.36	GO:0003690	double-stranded DNA binding

0.61

GO:0005634

nucleus

sp|P43688|NKX26_MOUSE
Homeobox protein Nkx-2.6
Search

NKX2-6

0.90	Homeobox protein Nkx-2.6

0.62	GO:0007507	heart development
0.57	GO:1903779	regulation of cardiac conduction
0.57	GO:0006355	regulation of transcription, DNA-templated
0.56	GO:0035295	tube development
0.56	GO:0060048	cardiac muscle contraction
0.55	GO:0060037	pharyngeal system development
0.55	GO:0055123	digestive system development
0.55	GO:0009888	tissue development
0.55	GO:0048568	embryonic organ development
0.54	GO:0051146	striated muscle cell differentiation

0.65	GO:0043565	sequence-specific DNA binding
0.50	GO:0003700	DNA binding transcription factor activity
0.42	GO:0001012	RNA polymerase II regulatory region DNA binding
0.40	GO:0003690	double-stranded DNA binding
0.40	GO:0035326	enhancer binding
0.37	GO:0003682	chromatin binding
0.37	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.37	GO:0008134	transcription factor binding
0.36	GO:0001104	RNA polymerase II transcription cofactor activity
0.36	GO:0042803	protein homodimerization activity

0.61	GO:0005634	nucleus
0.37	GO:0032993	protein-DNA complex
0.37	GO:0005667	transcription factor complex
0.35	GO:0044446	intracellular organelle part
0.33	GO:0005576	extracellular region
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P43883|PLIN2_MOUSE
Perilipin-2
Search

PLIN2

0.91

Perilipin

0.74	GO:0019915	lipid storage
0.72	GO:0015909	long-chain fatty acid transport
0.48	GO:0014070	response to organic cyclic compound
0.45	GO:0042493	response to drug
0.39	GO:0019216	regulation of lipid metabolic process

0.36

GO:0005515

protein binding

0.79	GO:0005811	lipid droplet
0.61	GO:0005829	cytosol
0.56	GO:0005634	nucleus
0.51	GO:0005886	plasma membrane
0.37	GO:0005783	endoplasmic reticulum
0.36	GO:0005576	extracellular region

sp|P45376|ALDR_MOUSE
Aldose reductase
Search

AKR1B1

0.39	Aldo-keto reductase

0.54	GO:0044598	doxorubicin metabolic process
0.54	GO:0044597	daunorubicin metabolic process
0.53	GO:0071475	cellular hyperosmotic salinity response
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0003091	renal water homeostasis
0.50	GO:0035809	regulation of urine volume
0.47	GO:0072001	renal system development
0.46	GO:0043066	negative regulation of apoptotic process
0.43	GO:0006061	sorbitol biosynthetic process
0.42	GO:0090420	naphthalene-containing compound metabolic process

0.55	GO:0004032	alditol:NADP+ 1-oxidoreductase activity
0.55	GO:0043795	glyceraldehyde oxidoreductase activity
0.35	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
0.33	GO:0009055	electron transfer activity

0.45	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.42	GO:0097454	Schwann cell microvillus
0.41	GO:0033010	paranodal junction
0.41	GO:0043220	Schmidt-Lanterman incisure
0.41	GO:0042629	mast cell granule
0.39	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle

0.55	EC:1.1.1.21	GO:0004032
0.55	KEGG:R02820	GO:0004032

sp|P45377|ALD2_MOUSE
Aldose reductase-related protein 2
Search

0.77	Aldo-keto reductase like

0.53	GO:0055114	oxidation-reduction process
0.50	GO:0044598	doxorubicin metabolic process
0.50	GO:0044597	daunorubicin metabolic process
0.45	GO:0016488	farnesol catabolic process
0.44	GO:0071475	cellular hyperosmotic salinity response
0.43	GO:0003091	renal water homeostasis
0.43	GO:0035809	regulation of urine volume
0.41	GO:0072001	renal system development
0.41	GO:0043066	negative regulation of apoptotic process
0.40	GO:0001523	retinoid metabolic process

0.54	GO:0016491	oxidoreductase activity
0.40	GO:0016918	retinal binding
0.38	GO:0070401	NADP+ binding
0.38	GO:0070402	NADPH binding
0.33	GO:0005515	protein binding

0.42	GO:0005829	cytosol
0.39	GO:0070062	extracellular exosome
0.39	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part

0.54

EC:1

GO:0016491

sp|P45448|NR5A2_MOUSE
Nuclear receptor subfamily 5 group A member 2
Search

NR5A2

0.97	Steroidogenic factor 2

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.59	GO:0031016	pancreas development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0008206	bile acid metabolic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:0045070	positive regulation of viral genome replication
0.56	GO:0010468	regulation of gene expression
0.56	GO:0030855	epithelial cell differentiation
0.56	GO:0042632	cholesterol homeostasis

0.80	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0035326	enhancer binding
0.54	GO:0003682	chromatin binding
0.52	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding
0.51	GO:0005543	phospholipid binding
0.34	GO:0044877	macromolecular complex binding

0.61	GO:0005634	nucleus
0.52	GO:0005667	transcription factor complex
0.44	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm
0.33	GO:0043233	organelle lumen
0.33	GO:0005694	chromosome

sp|P45481|CBP_MOUSE
CREB-binding protein
Search

CREBBP

0.85	CREB binding protein b

0.78	GO:0016573	histone acetylation
0.65	GO:0018076	N-terminal peptidyl-lysine acetylation
0.61	GO:0031648	protein destabilization
0.60	GO:0034644	cellular response to UV
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0051254	positive regulation of RNA metabolic process
0.53	GO:0010557	positive regulation of macromolecule biosynthetic process
0.53	GO:0031328	positive regulation of cellular biosynthetic process

0.80	GO:0004402	histone acetyltransferase activity
0.77	GO:0003713	transcription coactivator activity
0.63	GO:0008270	zinc ion binding
0.63	GO:0043426	MRF binding
0.60	GO:0002039	p53 binding
0.60	GO:0001085	RNA polymerase II transcription factor binding
0.59	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.58	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0000987	proximal promoter sequence-specific DNA binding
0.56	GO:0003682	chromatin binding

0.74	GO:0000123	histone acetyltransferase complex
0.55	GO:0016604	nuclear body
0.53	GO:0000790	nuclear chromatin
0.41	GO:0005667	transcription factor complex
0.41	GO:0005737	cytoplasm
0.38	GO:0000940	condensed chromosome outer kinetochore

0.80

EC:2.3.1.48

GO:0004402

sp|P45591|COF2_MOUSE
Cofilin-2
Search

CFL2

0.96	Cofilin 2 homolog (Predicted)

0.84	GO:0030042	actin filament depolymerization
0.58	GO:0030836	positive regulation of actin filament depolymerization
0.55	GO:0046716	muscle cell cellular homeostasis
0.54	GO:0045214	sarcomere organization
0.53	GO:0007519	skeletal muscle tissue development
0.46	GO:0001842	neural fold formation
0.44	GO:0001755	neural crest cell migration
0.44	GO:0044794	positive regulation by host of viral process
0.44	GO:0061001	regulation of dendritic spine morphogenesis
0.44	GO:0043200	response to amino acid

0.74	GO:0003779	actin binding
0.54	GO:0032403	protein complex binding
0.41	GO:0005102	receptor binding
0.37	GO:0019903	protein phosphatase binding
0.37	GO:1902936	phosphatidylinositol bisphosphate binding
0.34	GO:0046872	metal ion binding

0.74	GO:0015629	actin cytoskeleton
0.53	GO:0030018	Z disc
0.45	GO:0030027	lamellipodium
0.44	GO:0016363	nuclear matrix
0.43	GO:0030863	cortical cytoskeleton
0.42	GO:0005615	extracellular space
0.42	GO:0005911	cell-cell junction
0.40	GO:0032587	ruffle membrane
0.40	GO:0044430	cytoskeletal part
0.38	GO:1903561	extracellular vesicle

sp|P45700|MA1A1_MOUSE
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA
Search

MAN1A1

0.47	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA

0.51	GO:0006491	N-glycan processing
0.47	GO:0007585	respiratory gaseous exchange
0.47	GO:0048286	lung alveolus development
0.39	GO:0006486	protein glycosylation
0.37	GO:0036507	protein demannosylation

0.82	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.70	GO:0005509	calcium ion binding

0.55	GO:0000139	Golgi membrane
0.55	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.47	GO:0005829	cytosol
0.46	GO:0005783	endoplasmic reticulum
0.40	GO:0070062	extracellular exosome
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.30	GO:0016021	integral component of membrane

0.82	EC:3.2.1.113	GO:0004571
0.82	KEGG:R05982 KEGG:R06722	GO:0004571

sp|P45878|FKBP2_MOUSE
Peptidyl-prolyl cis-trans isomerase FKBP2
Search

FKBP2

0.56	Peptidyl-prolyl cis-trans isomerase FKBP2

0.69	GO:0061077	chaperone-mediated protein folding
0.64	GO:0000413	protein peptidyl-prolyl isomerization

0.75	GO:0005528	FK506 binding
0.64	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.45	GO:0005515	protein binding

0.64	GO:0005789	endoplasmic reticulum membrane
0.54	GO:0070062	extracellular exosome

0.64

GO:0003755

sp|P45952|ACADM_MOUSE
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
Search

ACADM

0.93	Acyl-Coenzyme A dehydrogenase C-4 to C-12 straight chain

0.75	GO:0006635	fatty acid beta-oxidation
0.57	GO:0019254	carnitine metabolic process, CoA-linked
0.55	GO:0051791	medium-chain fatty acid metabolic process
0.53	GO:0055007	cardiac muscle cell differentiation
0.53	GO:0001889	liver development
0.53	GO:0006111	regulation of gluconeogenesis
0.51	GO:0009409	response to cold
0.50	GO:0009791	post-embryonic development
0.50	GO:0042594	response to starvation
0.49	GO:0005978	glycogen biosynthetic process

0.86	GO:0070991	medium-chain-acyl-CoA dehydrogenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding

0.59	GO:0005739	mitochondrion
0.52	GO:0016607	nuclear speck

0.86

EC:1.3.99

GO:0070991

sp|P46061|RAGP1_MOUSE
Ran GTPase-activating protein 1
Search

RANGAP1

0.88	Ran GTPase-activating protein 1

0.74	GO:0043547	positive regulation of GTPase activity
0.60	GO:0046826	negative regulation of protein export from nucleus
0.59	GO:0007165	signal transduction
0.44	GO:1904117	cellular response to vasopressin
0.42	GO:0048678	response to axon injury
0.35	GO:0016925	protein sumoylation
0.35	GO:0007062	sister chromatid cohesion

0.75	GO:0005096	GTPase activator activity
0.55	GO:0045296	cadherin binding
0.55	GO:0008536	Ran GTPase binding
0.44	GO:0003723	RNA binding
0.40	GO:0031625	ubiquitin protein ligase binding

0.58	GO:0016235	aggresome
0.55	GO:0031965	nuclear membrane
0.54	GO:0048471	perinuclear region of cytoplasm
0.54	GO:0000776	kinetochore
0.49	GO:0005829	cytosol
0.42	GO:0044614	nuclear pore cytoplasmic filaments
0.42	GO:1904115	axon cytoplasm
0.41	GO:0030425	dendrite
0.41	GO:0072686	mitotic spindle
0.37	GO:0000779	condensed chromosome, centromeric region

sp|P46062|SIPA1_MOUSE
Signal-induced proliferation-associated protein 1
Search

SIPA1

0.97	Signal-induced proliferation-associated protein 1

0.76	GO:0051056	regulation of small GTPase mediated signal transduction
0.76	GO:0043547	positive regulation of GTPase activity
0.60	GO:0048814	regulation of dendrite morphogenesis
0.55	GO:0031532	actin cytoskeleton reorganization
0.44	GO:0048013	ephrin receptor signaling pathway
0.44	GO:0050770	regulation of axonogenesis
0.44	GO:0042631	cellular response to water deprivation
0.40	GO:0051726	regulation of cell cycle
0.37	GO:0030308	negative regulation of cell growth
0.37	GO:0007162	negative regulation of cell adhesion

0.76	GO:0005096	GTPase activator activity
0.45	GO:0046875	ephrin receptor binding
0.42	GO:0008022	protein C-terminus binding
0.32	GO:0031625	ubiquitin protein ligase binding
0.32	GO:0019901	protein kinase binding
0.32	GO:0051015	actin filament binding

0.41	GO:0030133	transport vesicle
0.39	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0043234	protein complex
0.36	GO:0005634	nucleus
0.36	GO:0043197	dendritic spine
0.36	GO:0014069	postsynaptic density
0.35	GO:0005829	cytosol
0.35	GO:0045211	postsynaptic membrane
0.35	GO:0030054	cell junction
0.34	GO:0005856	cytoskeleton

sp|P46096|SYT1_MOUSE
Synaptotagmin-1
Search

SYT1

0.88	Synaptotagmin Ia

0.82	GO:0099643	signal release from synapse
0.82	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.75	GO:0006836	neurotransmitter transport
0.72	GO:0001505	regulation of neurotransmitter levels
0.68	GO:0051649	establishment of localization in cell
0.62	GO:1903861	positive regulation of dendrite extension
0.59	GO:0017158	regulation of calcium ion-dependent exocytosis
0.56	GO:0017156	calcium ion regulated exocytosis
0.56	GO:0097479	synaptic vesicle localization
0.56	GO:0099003	vesicle-mediated transport in synapse

0.81	GO:0005544	calcium-dependent phospholipid binding
0.57	GO:0050750	low-density lipoprotein particle receptor binding
0.56	GO:0019905	syntaxin binding
0.55	GO:0048306	calcium-dependent protein binding
0.50	GO:0005509	calcium ion binding
0.49	GO:0030276	clathrin binding
0.47	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.41	GO:0001786	phosphatidylserine binding
0.40	GO:0005516	calmodulin binding
0.40	GO:0008022	protein C-terminus binding

0.81	GO:0008021	synaptic vesicle
0.59	GO:0099501	exocytic vesicle membrane
0.57	GO:0031045	dense core granule
0.55	GO:0042734	presynaptic membrane
0.52	GO:0030424	axon
0.48	GO:0005794	Golgi apparatus
0.48	GO:0005829	cytosol
0.45	GO:0042584	chromaffin granule membrane
0.41	GO:0030054	cell junction
0.40	GO:0060076	excitatory synapse

sp|P46097|SYT2_MOUSE
Synaptotagmin-2
Search

SYT2

0.84	Synaptotagmin IIa

0.82	GO:0099643	signal release from synapse
0.82	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.76	GO:0006836	neurotransmitter transport
0.72	GO:0001505	regulation of neurotransmitter levels
0.68	GO:0051649	establishment of localization in cell
0.67	GO:1903861	positive regulation of dendrite extension
0.58	GO:0017158	regulation of calcium ion-dependent exocytosis
0.56	GO:0017156	calcium ion regulated exocytosis
0.56	GO:0097479	synaptic vesicle localization
0.56	GO:0099003	vesicle-mediated transport in synapse

0.81	GO:0005544	calcium-dependent phospholipid binding
0.56	GO:0019905	syntaxin binding
0.54	GO:0050750	low-density lipoprotein particle receptor binding
0.52	GO:0048306	calcium-dependent protein binding
0.50	GO:0030276	clathrin binding
0.50	GO:0005509	calcium ion binding
0.45	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.41	GO:0001786	phosphatidylserine binding
0.39	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding
0.39	GO:0005516	calmodulin binding

0.82	GO:0008021	synaptic vesicle
0.59	GO:0099501	exocytic vesicle membrane
0.54	GO:0031045	dense core granule
0.52	GO:0042734	presynaptic membrane
0.51	GO:0030424	axon
0.46	GO:0005794	Golgi apparatus
0.46	GO:0005829	cytosol
0.45	GO:0042584	chromaffin granule membrane
0.41	GO:0030054	cell junction
0.40	GO:0043679	axon terminus

sp|P46099|KLF1_MOUSE
Krueppel-like factor 1
Search

KLF1

0.90	Erythroid differentiation transcription factor

0.60	GO:0030097	hemopoiesis
0.60	GO:0034101	erythrocyte homeostasis
0.57	GO:0045893	positive regulation of transcription, DNA-templated
0.55	GO:0030154	cell differentiation
0.54	GO:0071499	cellular response to laminar fluid shear stress
0.52	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.48	GO:1904998	negative regulation of leukocyte adhesion to arterial endothelial cell
0.48	GO:2000342	negative regulation of chemokine (C-X-C motif) ligand 2 production
0.48	GO:0046985	positive regulation of hemoglobin biosynthetic process
0.48	GO:0045415	negative regulation of interleukin-8 biosynthetic process

0.57	GO:0000987	proximal promoter sequence-specific DNA binding
0.48	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.46	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting
0.46	GO:1990841	promoter-specific chromatin binding
0.45	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.45	GO:0001085	RNA polymerase II transcription factor binding
0.45	GO:0008013	beta-catenin binding
0.44	GO:0001047	core promoter binding
0.40	GO:0033613	activating transcription factor binding
0.38	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding

0.57	GO:0000790	nuclear chromatin
0.52	GO:0005654	nucleoplasm
0.45	GO:0000791	euchromatin
0.43	GO:0044798	nuclear transcription factor complex
0.35	GO:0005737	cytoplasm
0.32	GO:0048475	coated membrane
0.32	GO:0098796	membrane protein complex

sp|P46412|GPX3_MOUSE
Glutathione peroxidase 3
Search

0.47	Epididymal secretory glutathione peroxidase

0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.53	GO:0051289	protein homotetramerization
0.52	GO:0055114	oxidation-reduction process
0.45	GO:0042744	hydrogen peroxide catabolic process
0.43	GO:0033554	cellular response to stress
0.36	GO:0010269	response to selenium ion
0.36	GO:0051412	response to corticosterone
0.36	GO:0002238	response to molecule of fungal origin
0.35	GO:0006749	glutathione metabolic process

0.79	GO:0004602	glutathione peroxidase activity
0.53	GO:0008430	selenium binding
0.34	GO:0008134	transcription factor binding

0.54	GO:0005615	extracellular space
0.53	GO:0097524	sperm plasma membrane
0.37	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.79

EC:1.11.1.9

GO:0004602

sp|P46414|CDN1B_MOUSE
Cyclin-dependent kinase inhibitor 1B
Search

CDKN1B

0.85	Cyclin dependent kinase inhibitor

0.84	GO:0007050	cell cycle arrest
0.82	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.75	GO:0042127	regulation of cell proliferation
0.64	GO:1902746	regulation of lens fiber cell differentiation
0.63	GO:1904030	negative regulation of cyclin-dependent protein kinase activity
0.62	GO:0071236	cellular response to antibiotic
0.62	GO:0071285	cellular response to lithium ion
0.61	GO:0048102	autophagic cell death
0.60	GO:0031116	positive regulation of microtubule polymerization
0.59	GO:0000082	G1/S transition of mitotic cell cycle

0.85	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.58	GO:0019903	protein phosphatase binding
0.58	GO:0030332	cyclin binding
0.55	GO:0019901	protein kinase binding
0.54	GO:0032403	protein complex binding
0.52	GO:0016301	kinase activity
0.42	GO:0030544	Hsp70 protein binding
0.40	GO:0051087	chaperone binding
0.37	GO:0060089	molecular transducer activity
0.36	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity

0.61	GO:0005634	nucleus
0.60	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex
0.51	GO:0005829	cytosol
0.41	GO:0005768	endosome
0.36	GO:0043234	protein complex
0.35	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:1902554	serine/threonine protein kinase complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle

0.36

GO:0016773

sp|P46425|GSTP2_MOUSE
Glutathione S-transferase P 2
Search

GSTP1

0.69	Glutathione S-transferase pi

0.56	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process
0.56	GO:0071638	negative regulation of monocyte chemotactic protein-1 production
0.55	GO:0043508	negative regulation of JUN kinase activity
0.55	GO:0032691	negative regulation of interleukin-1 beta production
0.55	GO:0043651	linoleic acid metabolic process
0.54	GO:0032720	negative regulation of tumor necrosis factor production
0.53	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.53	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.51	GO:0071466	cellular response to xenobiotic stimulus
0.50	GO:0006749	glutathione metabolic process

0.76	GO:0004364	glutathione transferase activity
0.59	GO:0035730	S-nitrosoglutathione binding
0.52	GO:0035731	dinitrosyl-iron complex binding
0.51	GO:0004602	glutathione peroxidase activity
0.42	GO:0008432	JUN kinase binding
0.39	GO:0019207	kinase regulator activity
0.39	GO:0043295	glutathione binding
0.37	GO:0070026	nitric oxide binding
0.35	GO:0008144	drug binding

0.57	GO:0097057	TRAF2-GSTP1 complex
0.47	GO:0005829	cytosol
0.46	GO:0005739	mitochondrion
0.42	GO:0098788	dendritic knob
0.41	GO:0005634	nucleus
0.41	GO:0071683	sensory dendrite
0.39	GO:0097014	ciliary plasm
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0070062	extracellular exosome
0.37	GO:1904813	ficolin-1-rich granule lumen

0.76

EC:2.5.1.18

GO:0004364

sp|P46460|NSF_MOUSE
Vesicle-fusing ATPase
Search

NSF

0.83	N-ethylmaleimide sensitive factor, vesicle fusing ATPase

0.51	GO:0001921	positive regulation of receptor recycling
0.47	GO:0045732	positive regulation of protein catabolic process
0.47	GO:0033059	cellular pigmentation
0.46	GO:0006813	potassium ion transport
0.45	GO:0021700	developmental maturation
0.45	GO:0051641	cellular localization
0.45	GO:0001654	eye development
0.44	GO:0048933	afferent axon development in posterior lateral line nerve
0.44	GO:0048929	efferent axon development in posterior lateral line nerve
0.44	GO:0048939	anterior lateral line nerve glial cell development

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0017075	syntaxin-1 binding
0.51	GO:0035255	ionotropic glutamate receptor binding
0.49	GO:0030165	PDZ domain binding
0.48	GO:0019901	protein kinase binding
0.46	GO:0032403	protein complex binding
0.43	GO:0042623	ATPase activity, coupled
0.36	GO:0017137	Rab GTPase binding

0.50	GO:0043209	myelin sheath
0.43	GO:0005829	cytosol
0.41	GO:0005765	lysosomal membrane
0.39	GO:0005886	plasma membrane
0.37	GO:0043198	dendritic shaft
0.36	GO:0014069	postsynaptic density
0.36	GO:0070062	extracellular exosome
0.36	GO:0005795	Golgi stack
0.34	GO:0030496	midbody
0.34	GO:0098793	presynapse

sp|P46467|VPS4B_MOUSE
Vacuolar protein sorting-associated protein 4B
Search

VPS4B

0.92	Vacuolar protein sorting-associating protein 4B

0.63	GO:0061738	late endosomal microautophagy
0.61	GO:0036258	multivesicular body assembly
0.58	GO:1903724	positive regulation of centriole elongation
0.58	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
0.57	GO:1903542	negative regulation of exosomal secretion
0.57	GO:1903543	positive regulation of exosomal secretion
0.57	GO:1902188	positive regulation of viral release from host cell
0.56	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway
0.55	GO:0000920	cell separation after cytokinesis
0.55	GO:1901673	regulation of mitotic spindle assembly

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008022	protein C-terminus binding
0.49	GO:0042803	protein homodimerization activity
0.46	GO:0016887	ATPase activity
0.36	GO:0019904	protein domain specific binding
0.34	GO:0017048	Rho GTPase binding
0.34	GO:0005198	structural molecule activity

0.56	GO:0090543	Flemming body
0.52	GO:0000922	spindle pole
0.52	GO:0010008	endosome membrane
0.51	GO:0005813	centrosome
0.47	GO:0005829	cytosol
0.46	GO:0005634	nucleus
0.44	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0005770	late endosome
0.38	GO:0070062	extracellular exosome
0.37	GO:0036452	ESCRT complex

0.46

GO:0016887

sp|P46471|PRS7_MOUSE
26S protease regulatory subunit 7
Search

PSMC2

0.82	26S proteasome regulatory subunit 7

0.78	GO:1901800	positive regulation of proteasomal protein catabolic process
0.67	GO:0030163	protein catabolic process
0.55	GO:0006508	proteolysis
0.51	GO:0043632	modification-dependent macromolecule catabolic process
0.47	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.45	GO:0034976	response to endoplasmic reticulum stress
0.45	GO:0010243	response to organonitrogen compound
0.43	GO:0044267	cellular protein metabolic process
0.36	GO:0001649	osteoblast differentiation
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition

0.79	GO:0036402	proteasome-activating ATPase activity
0.53	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0008233	peptidase activity
0.46	GO:0017025	TBP-class protein binding
0.32	GO:0046872	metal ion binding

0.57	GO:1905369	endopeptidase complex
0.53	GO:0036464	cytoplasmic ribonucleoprotein granule
0.49	GO:0005829	cytosol
0.48	GO:0043234	protein complex
0.42	GO:0031981	nuclear lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.35	GO:0043197	dendritic spine
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.50

GO:0008233

sp|P46638|RB11B_MOUSE
Ras-related protein Rab-11B
Search

0.45	GTP-binding protein YPT3

0.65	GO:0032402	melanosome transport
0.57	GO:0006887	exocytosis
0.57	GO:0060627	regulation of vesicle-mediated transport
0.56	GO:0010796	regulation of multivesicular body size
0.56	GO:0097734	extracellular exosome biogenesis
0.55	GO:0030953	astral microtubule organization
0.55	GO:0036258	multivesicular body assembly
0.55	GO:0045773	positive regulation of axon extension
0.54	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
0.54	GO:0072657	protein localization to membrane

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.63	GO:0031489	myosin V binding
0.50	GO:0019003	GDP binding
0.49	GO:0008017	microtubule binding
0.48	GO:0045296	cadherin binding
0.34	GO:0019905	syntaxin binding
0.34	GO:0019904	protein domain specific binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0016874	ligase activity

0.61	GO:0055037	recycling endosome
0.60	GO:0045335	phagocytic vesicle
0.54	GO:0005771	multivesicular body
0.54	GO:0032154	cleavage furrow
0.53	GO:0005828	kinetochore microtubule
0.52	GO:0070062	extracellular exosome
0.51	GO:0030424	axon
0.51	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005802	trans-Golgi network
0.51	GO:0000922	spindle pole

0.33

GO:0016874

sp|P46656|ADX_MOUSE
Adrenodoxin, mitochondrial
Search

FDX1

0.61	Adrenodoxin, mitochondrial

0.61	GO:0022900	electron transport chain
0.56	GO:1904321	response to forskolin
0.54	GO:0071320	cellular response to cAMP
0.53	GO:1901655	cellular response to ketone
0.53	GO:0008203	cholesterol metabolic process
0.51	GO:0035690	cellular response to drug
0.51	GO:0042446	hormone biosynthetic process
0.50	GO:0071396	cellular response to lipid
0.42	GO:1904087	negative regulation of epiboly involved in gastrulation with mouth forming second
0.42	GO:0006694	steroid biosynthetic process

0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.62	GO:0009055	electron transfer activity
0.36	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity
0.36	GO:0015039	NADPH-adrenodoxin reductase activity
0.36	GO:0046872	metal ion binding
0.35	GO:0008022	protein C-terminus binding
0.34	GO:0019899	enzyme binding
0.34	GO:0042803	protein homodimerization activity

0.44	GO:0005739	mitochondrion
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.33	GO:0031090	organelle membrane
0.33	GO:0031975	envelope
0.30	GO:0044425	membrane part

0.36

EC:1.14.15.6

GO:0008386

sp|P46660|AINX_MOUSE
Alpha-internexin
Search

INA

0.97	Internexin neuronal intermediate filament protein alpha

0.73	GO:0007399	nervous system development
0.59	GO:0120036	plasma membrane bounded cell projection organization
0.58	GO:0060052	neurofilament cytoskeleton organization
0.58	GO:0048468	cell development
0.55	GO:1990830	cellular response to leukemia inhibitory factor
0.40	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.38	GO:0048857	neural nucleus development
0.38	GO:0060322	head development
0.37	GO:0045110	intermediate filament bundle assembly
0.37	GO:0048513	animal organ development

0.62	GO:0005198	structural molecule activity
0.36	GO:0005515	protein binding
0.34	GO:0015643	toxic substance binding

0.85	GO:0005883	neurofilament
0.55	GO:0043209	myelin sheath
0.53	GO:0036464	cytoplasmic ribonucleoprotein granule
0.53	GO:0031965	nuclear membrane
0.49	GO:0097418	neurofibrillary tangle
0.49	GO:0005654	nucleoplasm
0.36	GO:0005615	extracellular space
0.36	GO:0030424	axon
0.35	GO:0031594	neuromuscular junction
0.35	GO:0014069	postsynaptic density

sp|P46662|MERL_MOUSE
Merlin
Search

NF2

0.91	Neurofibromin 2

0.67	GO:0014010	Schwann cell proliferation
0.64	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein
0.63	GO:0007398	ectoderm development
0.63	GO:0035330	regulation of hippo signaling
0.63	GO:0070306	lens fiber cell differentiation
0.62	GO:0051496	positive regulation of stress fiber assembly
0.62	GO:0021766	hippocampus development
0.61	GO:0001707	mesoderm formation
0.61	GO:0072091	regulation of stem cell proliferation
0.61	GO:0014013	regulation of gliogenesis

0.73

GO:0003779

actin binding

0.69	GO:0005856	cytoskeleton
0.61	GO:0097610	cell surface furrow
0.61	GO:0030175	filopodium
0.60	GO:0001726	ruffle
0.60	GO:0030027	lamellipodium
0.59	GO:0032155	cell division site part
0.59	GO:0044297	cell body
0.58	GO:0045177	apical part of cell
0.58	GO:0005769	early endosome
0.58	GO:0005912	adherens junction

sp|P46664|PURA2_MOUSE
Adenylosuccinate synthetase isozyme 2
Search

ADSS

0.45	Adenylosuccinate synthetase

0.72	GO:0044208	'de novo' AMP biosynthetic process
0.45	GO:0046040	IMP metabolic process
0.43	GO:0071257	cellular response to electrical stimulus
0.41	GO:0006531	aspartate metabolic process
0.40	GO:0014074	response to purine-containing compound
0.40	GO:0060359	response to ammonium ion
0.36	GO:0014850	response to muscle activity
0.35	GO:0035690	cellular response to drug
0.35	GO:0042594	response to starvation
0.35	GO:0002376	immune system process

0.79	GO:0004019	adenylosuccinate synthase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.59	GO:0000287	magnesium ion binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0042301	phosphate ion binding
0.35	GO:0051015	actin filament binding
0.35	GO:0042803	protein homodimerization activity
0.34	GO:0003924	GTPase activity

0.47	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:6.3.4.4	GO:0004019
0.79	KEGG:R01135	GO:0004019

sp|P46684|ZIC1_MOUSE
Zinc finger protein ZIC 1
Search

ZIC1

0.66	Zinc finger of the cerebellum 1

0.56	GO:0007420	brain development
0.48	GO:0060059	embryonic retina morphogenesis in camera-type eye
0.47	GO:0008589	regulation of smoothened signaling pathway
0.47	GO:0061351	neural precursor cell proliferation
0.46	GO:0007628	adult walking behavior
0.46	GO:0021510	spinal cord development
0.46	GO:0042307	positive regulation of protein import into nucleus
0.46	GO:0007389	pattern specification process
0.44	GO:0045944	positive regulation of transcription by RNA polymerase II
0.43	GO:0006366	transcription by RNA polymerase II

0.51	GO:0003676	nucleic acid binding
0.45	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0046872	metal ion binding
0.34	GO:0003682	chromatin binding
0.34	GO:0005515	protein binding

0.46	GO:0005634	nucleus
0.39	GO:0070013	intracellular organelle lumen
0.37	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P46686|TULP2_MOUSE
Tubby-related protein 2
Search

TULP2

0.88	Tubby like protein 2

0.81	GO:1903546	protein localization to photoreceptor outer segment
0.75	GO:0097500	receptor localization to non-motile cilium
0.61	GO:0050908	detection of light stimulus involved in visual perception
0.61	GO:0050766	positive regulation of phagocytosis
0.60	GO:0001895	retina homeostasis
0.60	GO:0006910	phagocytosis, recognition
0.59	GO:0042462	eye photoreceptor cell development
0.58	GO:0016358	dendrite development
0.58	GO:0060041	retina development in camera-type eye
0.36	GO:0000413	protein peptidyl-prolyl isomerization

0.70	GO:0035091	phosphatidylinositol binding
0.69	GO:0032403	protein complex binding
0.53	GO:0003779	actin binding
0.41	GO:0008081	phosphoric diester hydrolase activity
0.36	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0003700	DNA binding transcription factor activity

0.69	GO:0005929	cilium
0.59	GO:0001917	photoreceptor inner segment
0.58	GO:0043679	axon terminus
0.52	GO:0005576	extracellular region
0.50	GO:0005829	cytosol
0.44	GO:0044422	organelle part
0.44	GO:0005886	plasma membrane
0.39	GO:0030054	cell junction
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.41

EC:3.1.4

GO:0008081

sp|P46694|IEX1_MOUSE
Radiation-inducible immediate-early gene IEX-1
Search

IER3

0.94	Radiation-inducible immediate-early protein IEX-1

0.78	GO:0043066	negative regulation of apoptotic process
0.65	GO:2001020	regulation of response to DNA damage stimulus
0.50	GO:0045820	negative regulation of glycolytic process
0.49	GO:0003085	negative regulation of systemic arterial blood pressure
0.49	GO:1901028	regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
0.49	GO:0001562	response to protozoan
0.48	GO:0007095	mitotic G2 DNA damage checkpoint
0.48	GO:0010823	negative regulation of mitochondrion organization
0.48	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.48	GO:0050728	negative regulation of inflammatory response

0.35

GO:0005515

protein binding

0.52	GO:0005634	nucleus
0.40	GO:0005739	mitochondrion
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P46718|PDCD2_MOUSE
Programmed cell death protein 2
Search

PDCD2

0.91	Programmed cell death 2 alternative transcript

0.62	GO:1902035	positive regulation of hematopoietic stem cell proliferation
0.60	GO:1901532	regulation of hematopoietic progenitor cell differentiation
0.58	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.47	GO:0060218	hematopoietic stem cell differentiation
0.46	GO:0030218	erythrocyte differentiation
0.44	GO:0007088	regulation of mitotic nuclear division
0.42	GO:0012501	programmed cell death
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.51	GO:0019899	enzyme binding
0.36	GO:0003677	DNA binding
0.36	GO:0046872	metal ion binding

0.48	GO:0005737	cytoplasm
0.39	GO:0005634	nucleus
0.38	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|P46735|MYO1B_MOUSE
Unconventional myosin-Ib
Search

MYO1B

0.95	Unconventional myosin-Ib

0.74	GO:0007018	microtubule-based movement
0.52	GO:0006892	post-Golgi vesicle-mediated transport
0.50	GO:0007015	actin filament organization
0.48	GO:0030048	actin filament-based movement
0.41	GO:0022607	cellular component assembly
0.38	GO:0033572	transferrin transport
0.34	GO:0007399	nervous system development

0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.74	GO:0003779	actin binding
0.56	GO:0000146	microfilament motor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0045296	cadherin binding
0.50	GO:0032403	protein complex binding
0.48	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding

0.77	GO:0016459	myosin complex
0.54	GO:0032588	trans-Golgi network membrane
0.53	GO:0005884	actin filament
0.52	GO:0005769	early endosome
0.51	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0010008	endosome membrane
0.47	GO:0030175	filopodium
0.47	GO:0005903	brush border
0.42	GO:0005886	plasma membrane
0.38	GO:0045177	apical part of cell

sp|P46737|BRCC3_MOUSE
Lys-63-specific deubiquitinase BRCC36
Search

BRCC3

0.94	BRCA1/BRCA2-containing complex subunit 3

0.84	GO:0070536	protein K63-linked deubiquitination
0.64	GO:0006281	DNA repair
0.56	GO:0072425	signal transduction involved in G2 DNA damage checkpoint
0.55	GO:0045739	positive regulation of DNA repair
0.54	GO:0016578	histone deubiquitination
0.53	GO:0010212	response to ionizing radiation
0.45	GO:0050790	regulation of catalytic activity
0.43	GO:0001525	angiogenesis
0.39	GO:0051301	cell division
0.39	GO:0007049	cell cycle

0.78	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.54	GO:0031593	polyubiquitin modification-dependent protein binding
0.47	GO:0008237	metallopeptidase activity
0.46	GO:0030234	enzyme regulator activity
0.36	GO:0046872	metal ion binding
0.35	GO:0061578	Lys63-specific deubiquitinase activity

0.85	GO:0070552	BRISC complex
0.84	GO:0070531	BRCA1-A complex
0.50	GO:0000152	nuclear ubiquitin ligase complex
0.46	GO:0005654	nucleoplasm
0.41	GO:0000922	spindle pole
0.38	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P46935|NEDD4_MOUSE
E3 ubiquitin-protein ligase NEDD4
Search

0.29	E3 ubiquitin-protein ligase

0.73	GO:0016567	protein ubiquitination
0.59	GO:0006511	ubiquitin-dependent protein catabolic process
0.50	GO:0010768	negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage
0.49	GO:0050847	progesterone receptor signaling pathway
0.49	GO:2000650	negative regulation of sodium ion transmembrane transporter activity
0.49	GO:0019089	transmission of virus
0.48	GO:0042921	glucocorticoid receptor signaling pathway
0.48	GO:0006622	protein targeting to lysosome
0.48	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway
0.48	GO:0044111	development involved in symbiotic interaction

0.74	GO:0004842	ubiquitin-protein transferase activity
0.61	GO:0061659	ubiquitin-like protein ligase activity
0.50	GO:0016874	ligase activity
0.50	GO:0050816	phosphothreonine residue binding
0.50	GO:0031698	beta-2 adrenergic receptor binding
0.49	GO:0019871	sodium channel inhibitor activity
0.48	GO:0035255	ionotropic glutamate receptor binding
0.48	GO:0050815	phosphoserine residue binding
0.48	GO:0070064	proline-rich region binding
0.46	GO:0043130	ubiquitin binding

0.47	GO:0043197	dendritic spine
0.45	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0000151	ubiquitin ligase complex
0.44	GO:0005938	cell cortex
0.43	GO:0000785	chromatin
0.43	GO:0005794	Golgi apparatus
0.42	GO:0005829	cytosol
0.38	GO:0005886	plasma membrane

0.50	EC:6	GO:0016874
0.74	KEGG:R03876	GO:0004842

sp|P46938|YAP1_MOUSE
Transcriptional coactivator YAP1
Search

YAP1

0.86	Yes-associated protein 1

0.85	GO:1905480	positive regulation of glutamate-ammonia ligase activity
0.84	GO:0046620	regulation of organ growth
0.82	GO:0003007	heart morphogenesis
0.81	GO:0039022	pronephric duct development
0.81	GO:0048514	blood vessel morphogenesis
0.80	GO:0003406	retinal pigment epithelium development
0.80	GO:0048568	embryonic organ development
0.80	GO:0048589	developmental growth
0.79	GO:0048916	posterior lateral line development
0.78	GO:0043066	negative regulation of apoptotic process

0.64	GO:0070064	proline-rich region binding
0.62	GO:0033613	activating transcription factor binding
0.61	GO:0008022	protein C-terminus binding
0.60	GO:0003714	transcription corepressor activity
0.59	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.59	GO:0003713	transcription coactivator activity
0.58	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.57	GO:0003682	chromatin binding
0.56	GO:0046982	protein heterodimerization activity

0.68	GO:0071148	TEAD-1-YAP complex
0.67	GO:0071149	TEAD-2-YAP complex
0.65	GO:0000785	chromatin
0.52	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P46978|STT3A_MOUSE
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A
Search

STT3A

0.91	STT3A, catalytic subunit of the oligosaccharyltransferase complex

0.76	GO:0043686	co-translational protein modification
0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.73	GO:0018196	peptidyl-asparagine modification
0.51	GO:0043687	post-translational protein modification

0.83

GO:0004576

oligosaccharyl transferase activity

0.52	GO:0008250	oligosaccharyltransferase complex
0.30	GO:0031224	intrinsic component of membrane

0.83

GO:0004576

sp|P47199|QOR_MOUSE
Quinone oxidoreductase
Search

CRYZ

0.48	Quinone oxidoreductase

0.53	GO:0051289	protein homotetramerization
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0042178	xenobiotic catabolic process
0.34	GO:0007601	visual perception

0.62	GO:0008270	zinc ion binding
0.54	GO:0003960	NADPH:quinone reductase activity
0.53	GO:0003730	mRNA 3'-UTR binding
0.52	GO:0070402	NADPH binding
0.44	GO:0070404	NADH binding
0.35	GO:0005212	structural constituent of eye lens
0.33	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.47	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.54

EC:1.6.5.5

GO:0003960

sp|P47212|GALA_MOUSE
Galanin peptides
Search

GAL

0.97	Galanin and GMAP prepropeptide

0.75	GO:0010469	regulation of receptor activity
0.63	GO:1902890	regulation of root hair elongation
0.62	GO:1902608	positive regulation of large conductance calcium-activated potassium channel activity
0.62	GO:1905422	negative regulation of plant organ morphogenesis
0.62	GO:1903889	negative regulation of plant epidermal cell differentiation
0.61	GO:0051795	positive regulation of timing of catagen
0.61	GO:0051464	positive regulation of cortisol secretion
0.60	GO:1903430	negative regulation of cell maturation
0.60	GO:0010737	protein kinase A signaling
0.58	GO:0007218	neuropeptide signaling pathway

0.79	GO:0005179	hormone activity
0.65	GO:0031763	galanin receptor binding
0.61	GO:0004966	galanin receptor activity

0.66	GO:0005576	extracellular region
0.55	GO:0043025	neuronal cell body
0.49	GO:0030141	secretory granule
0.40	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

sp|P47226|TES_MOUSE
Testin
Search

TES

0.94	Testis derived transcript

0.76	GO:0042127	regulation of cell proliferation
0.52	GO:0048523	negative regulation of cellular process
0.36	GO:0001755	neural crest cell migration
0.33	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling

0.63	GO:0008270	zinc ion binding
0.55	GO:0045296	cadherin binding
0.34	GO:0003723	RNA binding

0.62	GO:0005925	focal adhesion
0.48	GO:0005829	cytosol
0.44	GO:0043234	protein complex
0.42	GO:0005886	plasma membrane
0.35	GO:0005938	cell cortex
0.34	GO:0005634	nucleus

sp|P47239|PAX7_MOUSE
Paired box protein Pax-7
Search

PAX7

0.92	Paired box protein 7 alpha variant 3

0.69	GO:0007275	multicellular organism development
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0042060	wound healing
0.52	GO:2000288	positive regulation of myoblast proliferation
0.51	GO:0045595	regulation of cell differentiation
0.51	GO:0031062	positive regulation of histone methylation
0.50	GO:0031099	regeneration

0.64	GO:0043565	sequence-specific DNA binding
0.51	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex

sp|P47242|PAX9_MOUSE
Paired box protein Pax-9
Search

PAX9

0.93	Paired box transcription factor

0.76	GO:0009887	animal organ morphogenesis
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0042481	regulation of odontogenesis
0.56	GO:0060325	face morphogenesis
0.55	GO:0007492	endoderm development
0.52	GO:0071363	cellular response to growth factor stimulus
0.49	GO:1902680	positive regulation of RNA biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.51	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0005310	dicarboxylic acid transmembrane transporter activity
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex
0.33	GO:0005743	mitochondrial inner membrane
0.30	GO:0016021	integral component of membrane

sp|P47708|RP3A_MOUSE
Rabphilin-3A
Search

RPH3A

0.97

Rabphilin

0.69	GO:0006886	intracellular protein transport
0.51	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter
0.51	GO:0017158	regulation of calcium ion-dependent exocytosis
0.49	GO:0006906	vesicle fusion
0.36	GO:0010817	regulation of hormone levels
0.35	GO:0007420	brain development
0.35	GO:0031340	positive regulation of vesicle fusion
0.35	GO:1903307	positive regulation of regulated secretory pathway
0.35	GO:0050714	positive regulation of protein secretion
0.34	GO:0023056	positive regulation of signaling

0.77	GO:0017137	Rab GTPase binding
0.52	GO:0046872	metal ion binding
0.50	GO:0019905	syntaxin binding
0.49	GO:0005544	calcium-dependent phospholipid binding
0.48	GO:0030276	clathrin binding
0.40	GO:0070679	inositol 1,4,5 trisphosphate binding
0.40	GO:0008430	selenium binding
0.40	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.39	GO:0032403	protein complex binding
0.39	GO:0042301	phosphate ion binding

0.49	GO:0098793	presynapse
0.49	GO:0070382	exocytic vesicle
0.40	GO:0030141	secretory granule
0.40	GO:0005886	plasma membrane
0.39	GO:0030054	cell junction
0.38	GO:0030658	transport vesicle membrane
0.38	GO:0043005	neuron projection
0.38	GO:0019898	extrinsic component of membrane
0.37	GO:0005794	Golgi apparatus
0.37	GO:0005829	cytosol

sp|P47713|PA24A_MOUSE
Cytosolic phospholipase A2
Search

PLA2G4A

0.66	Cytosolic phospholipase A2

0.80	GO:0009395	phospholipid catabolic process
0.58	GO:0071236	cellular response to antibiotic
0.56	GO:0046456	icosanoid biosynthetic process
0.54	GO:0050482	arachidonic acid secretion
0.51	GO:0042127	regulation of cell proliferation
0.43	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.37	GO:0019369	arachidonic acid metabolic process
0.37	GO:0022602	ovulation cycle process
0.37	GO:0008585	female gonad development
0.36	GO:0036150	phosphatidylserine acyl-chain remodeling

0.82	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.82	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.79	GO:0004623	phospholipase A2 activity
0.57	GO:0005544	calcium-dependent phospholipid binding
0.53	GO:0046872	metal ion binding
0.45	GO:0004622	lysophospholipase activity
0.35	GO:0035035	histone acetyltransferase binding
0.35	GO:0008970	phosphatidylcholine 1-acylhydrolase activity

0.56	GO:0005811	lipid droplet
0.49	GO:0005829	cytosol
0.49	GO:0005794	Golgi apparatus
0.49	GO:0005783	endoplasmic reticulum
0.42	GO:0031410	cytoplasmic vesicle
0.35	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane

0.79

EC:3.1.1.4

GO:0004623

sp|P47738|ALDH2_MOUSE
Aldehyde dehydrogenase, mitochondrial
Search

ALDH2

0.39	Mitochondrial aldehyde dehydrogenase 2

0.52	GO:0055114	oxidation-reduction process
0.46	GO:0006068	ethanol catabolic process
0.36	GO:0033574	response to testosterone
0.36	GO:0055093	response to hyperoxia
0.36	GO:0032570	response to progesterone
0.36	GO:0035094	response to nicotine
0.36	GO:0071398	cellular response to fatty acid
0.36	GO:0032355	response to estradiol
0.36	GO:0001889	liver development
0.35	GO:0032496	response to lipopolysaccharide

0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.39	GO:0051287	NAD binding
0.35	GO:0005515	protein binding
0.33	GO:0009055	electron transfer activity
0.33	GO:0043168	anion binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding

0.45	GO:0005739	mitochondrion
0.40	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part
0.37	GO:0070062	extracellular exosome

0.69

EC:1.2.1

GO:0016620

sp|P47739|AL3A1_MOUSE
Aldehyde dehydrogenase, dimeric NADP-preferring
Search

ALDH3A1

0.43	Aldehyde dehydrogenase, dimeric NADP-preferring

0.66	GO:0006081	cellular aldehyde metabolic process
0.52	GO:0055114	oxidation-reduction process
0.49	GO:0033306	phytol metabolic process
0.46	GO:0007422	peripheral nervous system development
0.45	GO:0008544	epidermis development
0.44	GO:0007417	central nervous system development
0.38	GO:0051591	response to cAMP
0.37	GO:0051384	response to glucocorticoid
0.37	GO:0001666	response to hypoxia
0.37	GO:0007584	response to nutrient

0.76	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity
0.55	GO:0004029	aldehyde dehydrogenase (NAD) activity
0.53	GO:0008106	alcohol dehydrogenase (NADP+) activity
0.47	GO:0046577	long-chain-alcohol oxidase activity
0.46	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity
0.33	GO:0005515	protein binding

0.49	GO:0005783	endoplasmic reticulum
0.46	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.39	GO:0031090	organelle membrane
0.38	GO:0005740	mitochondrial envelope
0.36	GO:0005615	extracellular space
0.36	GO:0042579	microbody
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.34	GO:1903561	extracellular vesicle

0.76

EC:1.2.1.5

GO:0004030

sp|P47740|AL3A2_MOUSE
Fatty aldehyde dehydrogenase
Search

ALDH3A2

0.43	Fatty aldehyde dehydrogenase

0.67	GO:0006081	cellular aldehyde metabolic process
0.57	GO:0033306	phytol metabolic process
0.53	GO:0007422	peripheral nervous system development
0.52	GO:0055114	oxidation-reduction process
0.52	GO:0008544	epidermis development
0.50	GO:0007417	central nervous system development
0.39	GO:0006714	sesquiterpenoid metabolic process
0.35	GO:0030148	sphingolipid biosynthetic process
0.34	GO:0000302	response to reactive oxygen species
0.34	GO:0009062	fatty acid catabolic process

0.77	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity
0.55	GO:0004029	aldehyde dehydrogenase (NAD) activity
0.54	GO:0046577	long-chain-alcohol oxidase activity
0.44	GO:0008106	alcohol dehydrogenase (NADP+) activity
0.39	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity

0.48	GO:0005783	endoplasmic reticulum
0.41	GO:0031090	organelle membrane
0.41	GO:0005740	mitochondrial envelope
0.40	GO:0005829	cytosol
0.38	GO:0042579	microbody
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.37	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0098805	whole membrane

0.77

EC:1.2.1.5

GO:0004030

sp|P47741|TNR4_MOUSE
Tumor necrosis factor receptor superfamily member 4
Search

TNFRSF4

0.95	Tumor necrosis factor receptor superfamily member 4

0.60	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.57	GO:0032496	response to lipopolysaccharide
0.54	GO:0006954	inflammatory response
0.53	GO:0002376	immune system process
0.53	GO:0097190	apoptotic signaling pathway
0.52	GO:0042127	regulation of cell proliferation
0.52	GO:0042981	regulation of apoptotic process
0.51	GO:0007275	multicellular organism development
0.50	GO:0051047	positive regulation of secretion
0.50	GO:0051090	regulation of DNA binding transcription factor activity

0.61	GO:0005031	tumor necrosis factor-activated receptor activity
0.43	GO:0019955	cytokine binding
0.40	GO:0001618	virus receptor activity
0.32	GO:0046872	metal ion binding

0.50	GO:0009986	cell surface
0.48	GO:0005887	integral component of plasma membrane
0.47	GO:0098552	side of membrane
0.39	GO:0005829	cytosol

sp|P47743|GRM8_MOUSE
Metabotropic glutamate receptor 8
Search

GRM8

0.88	Metabotropic glutamate receptor 8

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0007215	glutamate receptor signaling pathway
0.48	GO:0051966	regulation of synaptic transmission, glutamatergic
0.37	GO:0035249	synaptic transmission, glutamatergic
0.36	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain
0.35	GO:0030818	negative regulation of cAMP biosynthetic process
0.35	GO:0046928	regulation of neurotransmitter secretion
0.35	GO:1901214	regulation of neuron death
0.34	GO:0007601	visual perception

0.72	GO:0004930	G-protein coupled receptor activity
0.52	GO:0008066	glutamate receptor activity

0.55	GO:0005886	plasma membrane
0.45	GO:0098793	presynapse
0.35	GO:0043025	neuronal cell body
0.34	GO:0098794	postsynapse
0.34	GO:0043005	neuron projection
0.30	GO:0016021	integral component of membrane

sp|P47746|CNR1_MOUSE
Cannabinoid receptor 1
Search

CNR1

0.91	Cannabinoid receptor

0.86	GO:0038171	cannabinoid signaling pathway
0.57	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.54	GO:0099553	trans-synaptic signaling by endocannabinoid, modulating synaptic transmission
0.52	GO:0007413	axonal fasciculation
0.49	GO:0042593	glucose homeostasis
0.41	GO:0033602	negative regulation of dopamine secretion
0.41	GO:0060405	regulation of penile erection
0.40	GO:0031999	negative regulation of fatty acid beta-oxidation
0.40	GO:0031622	positive regulation of fever generation
0.40	GO:0045759	negative regulation of action potential

0.86	GO:0004949	cannabinoid receptor activity
0.34	GO:0008144	drug binding
0.34	GO:0005515	protein binding

0.51	GO:0042734	presynaptic membrane
0.50	GO:0030426	growth cone
0.50	GO:0030424	axon
0.40	GO:0005741	mitochondrial outer membrane
0.39	GO:0045121	membrane raft
0.33	GO:0005887	integral component of plasma membrane

sp|P47750|TSHR_MOUSE
Thyrotropin receptor
Search

TSHR

0.95	Thyrotropin receptor

0.86	GO:0038194	thyroid-stimulating hormone signaling pathway
0.59	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.57	GO:0090103	cochlea morphogenesis
0.57	GO:0071542	dopaminergic neuron differentiation
0.56	GO:0060122	inner ear receptor cell stereocilium organization
0.56	GO:0040018	positive regulation of multicellular organism growth
0.55	GO:0030183	B cell differentiation
0.55	GO:0008344	adult locomotory behavior
0.52	GO:0040012	regulation of locomotion
0.51	GO:0007190	activation of adenylate cyclase activity

0.86	GO:0004996	thyroid-stimulating hormone receptor activity
0.48	GO:0008528	G-protein coupled peptide receptor activity
0.42	GO:0032403	protein complex binding

0.54	GO:0005886	plasma membrane
0.38	GO:0005622	intracellular
0.38	GO:0043235	receptor complex
0.35	GO:0045121	membrane raft
0.34	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|P47753|CAZA1_MOUSE
F-actin-capping protein subunit alpha-1
Search

CAPZA1

0.94	Capping actin protein of muscle Z-line alpha subunit 1

0.84	GO:0051016	barbed-end actin filament capping
0.51	GO:0034329	cell junction assembly
0.36	GO:0050878	regulation of body fluid levels
0.35	GO:0035722	interleukin-12-mediated signaling pathway
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0070495	negative regulation of thrombin-activated receptor signaling pathway
0.35	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity
0.35	GO:1901299	negative regulation of hydrogen peroxide-mediated programmed cell death
0.35	GO:0001886	endothelial cell morphogenesis
0.35	GO:2001028	positive regulation of endothelial cell chemotaxis

0.74	GO:0003779	actin binding
0.49	GO:0045296	cadherin binding
0.35	GO:0032403	protein complex binding
0.34	GO:0019903	protein phosphatase binding
0.34	GO:0004713	protein tyrosine kinase activity
0.33	GO:0042802	identical protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008144	drug binding

0.84	GO:0008290	F-actin capping protein complex
0.52	GO:0071203	WASH complex
0.44	GO:0005903	brush border
0.43	GO:0030863	cortical cytoskeleton
0.38	GO:0030018	Z disc
0.36	GO:0070062	extracellular exosome
0.35	GO:0005911	cell-cell junction
0.34	GO:0009925	basal plasma membrane
0.34	GO:0005829	cytosol
0.33	GO:0005634	nucleus

0.34

GO:0004713

sp|P47754|CAZA2_MOUSE
F-actin-capping protein subunit alpha-2
Search

CAPZA2

0.89	F-actin-capping protein subunit alpha-2

0.79	GO:0051016	barbed-end actin filament capping
0.36	GO:0034329	cell junction assembly
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0007596	blood coagulation
0.34	GO:0045087	innate immune response
0.34	GO:0006888	ER to Golgi vesicle-mediated transport
0.34	GO:0006461	protein complex assembly

0.70	GO:0003779	actin binding
0.34	GO:0045296	cadherin binding

0.79	GO:0008290	F-actin capping protein complex
0.48	GO:0005903	brush border
0.47	GO:0030863	cortical cytoskeleton
0.36	GO:0070062	extracellular exosome
0.36	GO:0071203	WASH complex
0.35	GO:0005829	cytosol
0.35	GO:0030018	Z disc
0.30	GO:0016020	membrane

sp|P47757|CAPZB_MOUSE
F-actin-capping protein subunit beta
Search

CAPZB

0.79	Capping actin protein of muscle Z-line beta subunit

0.84	GO:0051016	barbed-end actin filament capping
0.73	GO:0030036	actin cytoskeleton organization
0.62	GO:0031115	negative regulation of microtubule polymerization
0.61	GO:0090036	regulation of protein kinase C signaling
0.60	GO:0030032	lamellipodium assembly
0.59	GO:0048747	muscle fiber development
0.55	GO:0031175	neuron projection development
0.50	GO:0051490	negative regulation of filopodium assembly
0.48	GO:0010591	regulation of lamellipodium assembly
0.44	GO:0000902	cell morphogenesis

0.74	GO:0003779	actin binding
0.58	GO:0048487	beta-tubulin binding
0.55	GO:0032403	protein complex binding

0.84	GO:0008290	F-actin capping protein complex
0.60	GO:0014704	intercalated disc
0.58	GO:0001669	acrosomal vesicle
0.58	GO:0005903	brush border
0.58	GO:0030018	Z disc
0.58	GO:0030027	lamellipodium
0.56	GO:0030863	cortical cytoskeleton
0.47	GO:0005884	actin filament
0.30	GO:0016020	membrane

sp|P47758|SRPRB_MOUSE
Signal recognition particle receptor subunit beta
Search

SRPRB

0.87	Signal recognition particle receptor subunit beta

0.36	GO:0036498	IRE1-mediated unfolded protein response
0.33	GO:0042157	lipoprotein metabolic process
0.33	GO:0006869	lipid transport
0.32	GO:0043086	negative regulation of catalytic activity

0.58	GO:0032550	purine ribonucleoside binding
0.58	GO:0019001	guanyl nucleotide binding
0.49	GO:0032555	purine ribonucleotide binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0005047	signal recognition particle binding
0.35	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0008289	lipid binding
0.32	GO:0004857	enzyme inhibitor activity
0.31	GO:0016787	hydrolase activity
0.31	GO:0003676	nucleic acid binding

0.53	GO:0005881	cytoplasmic microtubule
0.48	GO:0005785	signal recognition particle receptor complex
0.44	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.31

GO:0016787

sp|P47759|NSG2_MOUSE
Neuron-specific protein family member 2
Search

HGNC:24955

0.97	Neuronal vesicle trafficking-associated protein 2

0.85	GO:0007212	dopamine receptor signaling pathway
0.83	GO:0048268	clathrin coat assembly
0.51	GO:0016197	endosomal transport
0.47	GO:0099627	neurotransmitter receptor cycle
0.46	GO:1903540	establishment of protein localization to postsynaptic membrane
0.46	GO:0098877	neurotransmitter receptor transport to plasma membrane
0.46	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels
0.45	GO:0042982	amyloid precursor protein metabolic process
0.45	GO:0001881	receptor recycling
0.45	GO:0097120	receptor localization to synapse

0.85	GO:0032051	clathrin light chain binding
0.35	GO:0003730	mRNA 3'-UTR binding
0.34	GO:0045182	translation regulator activity
0.34	GO:0005102	receptor binding
0.32	GO:0003677	DNA binding

0.52	GO:0005768	endosome
0.50	GO:1990674	Golgi cis cisterna membrane
0.45	GO:0030659	cytoplasmic vesicle membrane
0.44	GO:0016328	lateral plasma membrane
0.43	GO:0098805	whole membrane
0.43	GO:0043202	lysosomal lumen
0.43	GO:0098794	postsynapse
0.43	GO:0097060	synaptic membrane
0.42	GO:0032588	trans-Golgi network membrane
0.41	GO:0030425	dendrite

sp|P47774|CCR7_MOUSE
C-C chemokine receptor type 7
Search

CCR7

0.97	C-C motif chemokine receptor 7

0.82	GO:0070098	chemokine-mediated signaling pathway
0.73	GO:0006954	inflammatory response
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.70	GO:0006935	chemotaxis
0.70	GO:0006955	immune response
0.67	GO:2000526	positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
0.67	GO:2000522	positive regulation of immunological synapse formation
0.67	GO:0072610	interleukin-12 secretion
0.66	GO:2000523	regulation of T cell costimulation
0.66	GO:0097029	mature conventional dendritic cell differentiation

0.83	GO:0004950	chemokine receptor activity
0.67	GO:0035757	chemokine (C-C motif) ligand 19 binding
0.67	GO:0035758	chemokine (C-C motif) ligand 21 binding
0.36	GO:0005044	scavenger receptor activity
0.35	GO:0015026	coreceptor activity
0.35	GO:0051916	granulocyte colony-stimulating factor binding
0.35	GO:0019960	C-X3-C chemokine binding

0.60	GO:0009897	external side of plasma membrane
0.48	GO:0005739	mitochondrion
0.41	GO:0097524	sperm plasma membrane
0.41	GO:0097225	sperm midpiece
0.41	GO:0097228	sperm principal piece
0.33	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

sp|P47791|GSHR_MOUSE
Glutathione reductase, mitochondrial
Search

GSR

0.52	Glutathione-disulfide reductase

0.74	GO:0006749	glutathione metabolic process
0.68	GO:0098869	cellular oxidant detoxification
0.66	GO:0045454	cell redox homeostasis
0.53	GO:0022900	electron transport chain
0.36	GO:0010041	response to iron(III) ion
0.36	GO:0033189	response to vitamin A
0.36	GO:0015949	nucleobase-containing small molecule interconversion
0.36	GO:0002931	response to ischemia
0.36	GO:0006979	response to oxidative stress
0.36	GO:0014823	response to activity

0.80	GO:0004362	glutathione-disulfide reductase activity
0.68	GO:0050661	NADP binding
0.65	GO:0050660	flavin adenine dinucleotide binding
0.54	GO:0009055	electron transfer activity
0.37	GO:0098622	selenodiglutathione-disulfide reductase activity
0.36	GO:0043295	glutathione binding
0.35	GO:0042803	protein homodimerization activity

0.52	GO:0009897	external side of plasma membrane
0.44	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.36	GO:0005829	cytosol
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

0.80

EC:1.8.1.7

GO:0004362

sp|P47801|EMP1_MOUSE
Epithelial membrane protein 1
Search

EMP1

0.97	Epithelial membrane protein 1

0.80	GO:0016049	cell growth
0.65	GO:0032060	bleb assembly
0.57	GO:0008219	cell death
0.35	GO:0008544	epidermis development
0.35	GO:0008283	cell proliferation
0.34	GO:0007275	multicellular organism development

0.34

GO:0005515

protein binding

0.45	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P47802|MTX1_MOUSE
Metaxin-1
Search

MTX1

0.95

Metaxin

0.78	GO:0006626	protein targeting to mitochondrion
0.40	GO:0007595	lactation
0.32	GO:0030198	extracellular matrix organization
0.32	GO:0007155	cell adhesion

0.32	GO:0008201	heparin binding
0.32	GO:0005509	calcium ion binding

0.77	GO:0005741	mitochondrial outer membrane
0.36	GO:0019866	organelle inner membrane
0.32	GO:0031012	extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

sp|P47806|GLI1_MOUSE
Zinc finger protein GLI1
Search

GLI1

0.87	GLI family zinc finger 1

0.81	GO:0007418	ventral midline development
0.81	GO:0007224	smoothened signaling pathway
0.81	GO:0060032	notochord regression
0.79	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation
0.78	GO:0021983	pituitary gland development
0.77	GO:0045880	positive regulation of smoothened signaling pathway
0.77	GO:2000345	regulation of hepatocyte proliferation
0.77	GO:0097421	liver regeneration
0.76	GO:0022037	metencephalon development
0.75	GO:0060045	positive regulation of cardiac muscle cell proliferation

0.72	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.70	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.67	GO:0003682	chromatin binding
0.64	GO:0008017	microtubule binding
0.40	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.39	GO:0008134	transcription factor binding
0.37	GO:0008270	zinc ion binding

0.78	GO:0097542	ciliary tip
0.71	GO:0005930	axoneme
0.61	GO:0005654	nucleoplasm
0.60	GO:0005829	cytosol
0.48	GO:0035301	Hedgehog signaling complex
0.39	GO:0031514	motile cilium
0.39	GO:0005730	nucleolus
0.30	GO:0016020	membrane

sp|P47809|MP2K4_MOUSE
Dual specificity mitogen-activated protein kinase kinase 4
Search

MAP2K4

0.92	Dual specificity mitogen-activated protein kinase kinase 4

0.63	GO:0006468	protein phosphorylation
0.54	GO:2000672	negative regulation of motor neuron apoptotic process
0.53	GO:0071260	cellular response to mechanical stimulus
0.53	GO:0034393	positive regulation of smooth muscle cell apoptotic process
0.49	GO:0009611	response to wounding
0.47	GO:0031098	stress-activated protein kinase signaling cascade
0.46	GO:0032147	activation of protein kinase activity
0.44	GO:0007346	regulation of mitotic cell cycle
0.43	GO:0072709	cellular response to sorbitol
0.42	GO:0061049	cell growth involved in cardiac muscle cell development

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0008545	JUN kinase kinase activity
0.41	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.36	GO:0004713	protein tyrosine kinase activity
0.33	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.41	GO:0032839	dendrite cytoplasm
0.40	GO:0043204	perikaryon
0.39	GO:0030424	axon
0.37	GO:0005829	cytosol
0.36	GO:0005634	nucleus

0.68

GO:0004674

sp|P47810|WEE1_MOUSE
Wee1-like protein kinase
Search

WEE1

0.93	WEE1 G2 checkpoint kinase

0.72	GO:0018108	peptidyl-tyrosine phosphorylation
0.70	GO:0000278	mitotic cell cycle
0.55	GO:0030010	establishment of cell polarity
0.54	GO:0048812	neuron projection morphogenesis
0.52	GO:0000226	microtubule cytoskeleton organization
0.42	GO:0009416	response to light stimulus
0.38	GO:0051301	cell division
0.38	GO:0051321	meiotic cell cycle
0.38	GO:0051726	regulation of cell cycle
0.37	GO:1900194	negative regulation of oocyte maturation

0.76	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.61	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0004674	protein serine/threonine kinase activity
0.36	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.58	GO:0005634	nucleus
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0043232	intracellular non-membrane-bounded organelle
0.44	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm

0.76

GO:0004715

sp|P47811|MK14_MOUSE
Mitogen-activated protein kinase 14
Search

MAPK14

0.57	Mitogen-activated protein kinase

0.79	GO:0000165	MAPK cascade
0.59	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration
0.59	GO:2001184	positive regulation of interleukin-12 secretion
0.58	GO:0090336	positive regulation of brown fat cell differentiation
0.58	GO:1905050	positive regulation of metallopeptidase activity
0.58	GO:0002741	positive regulation of cytokine secretion involved in immune response
0.58	GO:0090400	stress-induced premature senescence
0.58	GO:1901741	positive regulation of myoblast fusion
0.58	GO:0071223	cellular response to lipoteichoic acid
0.58	GO:0010759	positive regulation of macrophage chemotaxis

0.81	GO:0004707	MAP kinase activity
0.59	GO:0048273	mitogen-activated protein kinase p38 binding
0.59	GO:0051525	NFAT protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0019903	protein phosphatase binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004708	MAP kinase kinase activity
0.34	GO:0008022	protein C-terminus binding

0.53	GO:0016607	nuclear speck
0.52	GO:0000922	spindle pole
0.48	GO:0005829	cytosol
0.44	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen

0.81	EC:2.7.11.24	GO:0004707
0.81	KEGG:R00162	GO:0004707

sp|P47856|GFPT1_MOUSE
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
Search

GFPT1

0.77	Glucosamine--fructose-6-phosphate aminotransferase

0.59	GO:1901137	carbohydrate derivative biosynthetic process
0.53	GO:0032922	circadian regulation of gene expression
0.45	GO:0006047	UDP-N-acetylglucosamine metabolic process
0.45	GO:0006002	fructose 6-phosphate metabolic process
0.44	GO:0043413	macromolecule glycosylation
0.44	GO:0009100	glycoprotein metabolic process
0.39	GO:0036211	protein modification process
0.38	GO:0044267	cellular protein metabolic process
0.38	GO:1901566	organonitrogen compound biosynthetic process
0.37	GO:0009059	macromolecule biosynthetic process

0.75	GO:0004360	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
0.54	GO:0097367	carbohydrate derivative binding
0.34	GO:0016597	amino acid binding
0.34	GO:0051536	iron-sulfur cluster binding
0.34	GO:0030246	carbohydrate binding
0.33	GO:0005506	iron ion binding

0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.75	EC:2.6.1.16	GO:0004360
0.75	KEGG:R00768	GO:0004360

sp|P47857|PFKAM_MOUSE
ATP-dependent 6-phosphofructokinase, muscle type
Search

PFKM

0.46	ATP-dependent 6-phosphofructokinase

0.79	GO:0006002	fructose 6-phosphate metabolic process
0.78	GO:0061615	glycolytic process through fructose-6-phosphate
0.57	GO:0061718	glucose catabolic process to pyruvate
0.57	GO:0006735	NADH regeneration
0.55	GO:0046716	muscle cell cellular homeostasis
0.55	GO:0032024	positive regulation of insulin secretion
0.52	GO:0042593	glucose homeostasis
0.52	GO:0005980	glycogen catabolic process
0.50	GO:0051259	protein oligomerization
0.50	GO:0046835	carbohydrate phosphorylation

0.79	GO:0003872	6-phosphofructokinase activity
0.59	GO:0070061	fructose binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008022	protein C-terminus binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0019900	kinase binding
0.50	GO:0042802	identical protein binding
0.50	GO:0046872	metal ion binding
0.47	GO:0046983	protein dimerization activity

0.59	GO:0005945	6-phosphofructokinase complex
0.55	GO:0097228	sperm principal piece
0.53	GO:0016324	apical plasma membrane
0.44	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:2.7.1.11

GO:0003872

sp|P47867|SCG3_MOUSE
Secretogranin-3
Search

SCG3

0.97	Secretogranin III

0.55	GO:0002576	platelet degranulation
0.51	GO:0043687	post-translational protein modification

0.47	GO:0003723	RNA binding
0.44	GO:0005515	protein binding
0.36	GO:0003677	DNA binding

0.75	GO:0030658	transport vesicle membrane
0.64	GO:0005576	extracellular region
0.54	GO:0034774	secretory granule lumen
0.52	GO:0005788	endoplasmic reticulum lumen
0.37	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P47873|IL11_MOUSE
Interleukin-11
Search

IL11

0.97	Interleukin 11

0.84	GO:0046888	negative regulation of hormone secretion
0.82	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.81	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.78	GO:0008284	positive regulation of cell proliferation
0.77	GO:0043410	positive regulation of MAPK cascade
0.76	GO:0010469	regulation of receptor activity
0.73	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:1903659	regulation of complement-dependent cytotoxicity
0.48	GO:2000352	negative regulation of endothelial cell apoptotic process
0.42	GO:0030219	megakaryocyte differentiation

0.88	GO:0005142	interleukin-11 receptor binding
0.81	GO:0005125	cytokine activity
0.77	GO:0008083	growth factor activity

0.48	GO:0005737	cytoplasm
0.48	GO:0005615	extracellular space

sp|P47876|IBP1_MOUSE
Insulin-like growth factor-binding protein 1
Search

IGFBP1

0.93	Insulin like growth factor binding protein 1

0.76	GO:0001558	regulation of cell growth
0.51	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.44	GO:0031099	regeneration
0.41	GO:0008286	insulin receptor signaling pathway
0.40	GO:0045927	positive regulation of growth
0.40	GO:0007568	aging
0.40	GO:0042060	wound healing
0.40	GO:0048589	developmental growth
0.39	GO:0009888	tissue development
0.39	GO:0001666	response to hypoxia

0.84	GO:0005520	insulin-like growth factor binding
0.34	GO:0005102	receptor binding

0.66	GO:0005576	extracellular region
0.52	GO:0005794	Golgi apparatus
0.35	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

sp|P47877|IBP2_MOUSE
Insulin-like growth factor-binding protein 2
Search

IGFBP2

0.96	Insulin like growth factor binding protein 2

0.71	GO:0001558	regulation of cell growth
0.59	GO:0042104	positive regulation of activated T cell proliferation
0.53	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.52	GO:0032868	response to insulin
0.42	GO:0010226	response to lithium ion
0.41	GO:0032501	multicellular organismal process
0.41	GO:0032502	developmental process
0.41	GO:0032355	response to estradiol
0.41	GO:0048640	negative regulation of developmental growth
0.41	GO:0043627	response to estrogen

0.83	GO:0005520	insulin-like growth factor binding
0.35	GO:0005102	receptor binding
0.33	GO:0016746	transferase activity, transferring acyl groups

0.66	GO:0005576	extracellular region
0.40	GO:0016324	apical plasma membrane
0.38	GO:0031410	cytoplasmic vesicle
0.30	GO:0016021	integral component of membrane

0.33

GO:0016746

sp|P47878|IBP3_MOUSE
Insulin-like growth factor-binding protein 3
Search

IGFBP3

0.94	Insulin like growth factor binding protein 3

0.70	GO:0001558	regulation of cell growth
0.59	GO:0014912	negative regulation of smooth muscle cell migration
0.59	GO:0044342	type B pancreatic cell proliferation
0.58	GO:0045663	positive regulation of myoblast differentiation
0.58	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway
0.58	GO:0048662	negative regulation of smooth muscle cell proliferation
0.56	GO:0001649	osteoblast differentiation
0.55	GO:0010906	regulation of glucose metabolic process
0.54	GO:0043666	regulation of phosphoprotein phosphatase activity
0.54	GO:0043065	positive regulation of apoptotic process

0.83	GO:0005520	insulin-like growth factor binding
0.60	GO:0008160	protein tyrosine phosphatase activator activity
0.58	GO:0001968	fibronectin binding
0.33	GO:0046872	metal ion binding

0.66	GO:0005576	extracellular region
0.60	GO:0036454	growth factor complex
0.46	GO:0005634	nucleus
0.37	GO:0031091	platelet alpha granule
0.36	GO:0000792	heterochromatin
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0044432	endoplasmic reticulum part

sp|P47879|IBP4_MOUSE
Insulin-like growth factor-binding protein 4
Search

IGFBP4

0.97	Insulin like growth factor binding protein 4

0.77	GO:0001558	regulation of cell growth
0.62	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.61	GO:0044342	type B pancreatic cell proliferation
0.57	GO:0010906	regulation of glucose metabolic process
0.55	GO:0043410	positive regulation of MAPK cascade
0.42	GO:0042127	regulation of cell proliferation
0.40	GO:0014912	negative regulation of smooth muscle cell migration
0.40	GO:0045663	positive regulation of myoblast differentiation
0.40	GO:0006954	inflammatory response
0.39	GO:0032868	response to insulin

0.84	GO:0005520	insulin-like growth factor binding
0.41	GO:0008160	protein tyrosine phosphatase activator activity
0.39	GO:0001968	fibronectin binding
0.35	GO:0005102	receptor binding

0.66	GO:0005576	extracellular region
0.41	GO:0036454	growth factor complex
0.36	GO:0005634	nucleus
0.35	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0031091	platelet alpha granule
0.33	GO:0000792	heterochromatin
0.32	GO:0016324	apical plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P47880|IBP6_MOUSE
Insulin-like growth factor-binding protein 6
Search

IGFBP6

0.97	Insulin like growth factor binding protein 6

0.79	GO:0001558	regulation of cell growth
0.54	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.40	GO:0008285	negative regulation of cell proliferation
0.39	GO:0044342	type B pancreatic cell proliferation
0.39	GO:0014912	negative regulation of smooth muscle cell migration
0.38	GO:0001649	osteoblast differentiation
0.38	GO:0048660	regulation of smooth muscle cell proliferation
0.38	GO:0010906	regulation of glucose metabolic process
0.38	GO:0045663	positive regulation of myoblast differentiation
0.37	GO:0009968	negative regulation of signal transduction

0.84	GO:0005520	insulin-like growth factor binding
0.40	GO:0001968	fibronectin binding
0.38	GO:0008160	protein tyrosine phosphatase activator activity
0.36	GO:0005102	receptor binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0008374	O-acyltransferase activity

0.70	GO:0042568	insulin-like growth factor binary complex
0.41	GO:0005794	Golgi apparatus
0.40	GO:0070062	extracellular exosome
0.39	GO:0042567	insulin-like growth factor ternary complex
0.35	GO:0005634	nucleus
0.34	GO:0005578	proteinaceous extracellular matrix
0.33	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008374

sp|P47911|RL6_MOUSE
60S ribosomal protein L6
Search

RPL6

0.71	LOW QUALITY PROTEIN: 60S ribosomal protein L6

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.45	GO:0000027	ribosomal large subunit assembly
0.40	GO:0031016	pancreas development
0.39	GO:0043009	chordate embryonic development
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.63	GO:0003735	structural constituent of ribosome
0.46	GO:0045296	cadherin binding
0.40	GO:0003723	RNA binding
0.34	GO:0005247	voltage-gated chloride channel activity
0.33	GO:0003677	DNA binding
0.33	GO:0009982	pseudouridine synthase activity
0.33	GO:0016874	ligase activity

0.60	GO:0005840	ribosome
0.48	GO:0044445	cytosolic part
0.47	GO:0005844	polysome
0.45	GO:0036464	cytoplasmic ribonucleoprotein granule
0.42	GO:0044446	intracellular organelle part
0.40	GO:0005634	nucleus
0.36	GO:0005925	focal adhesion
0.35	GO:0031672	A band
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane

0.33

EC:5.4.99.12

GO:0009982

sp|P47915|RL29_MOUSE
60S ribosomal protein L29
Search

RPL29

0.70	60S ribosomal protein L29

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.37	GO:0035264	multicellular organism growth
0.37	GO:0031589	cell-substrate adhesion
0.36	GO:0008283	cell proliferation
0.35	GO:0007566	embryo implantation
0.35	GO:0000188	inactivation of MAPK activity
0.35	GO:0007568	aging

0.64	GO:0003735	structural constituent of ribosome
0.44	GO:0045296	cadherin binding
0.38	GO:0008201	heparin binding
0.35	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.34	GO:0003723	RNA binding
0.32	GO:0016301	kinase activity

0.61	GO:0005840	ribosome
0.50	GO:0044445	cytosolic part
0.43	GO:0044446	intracellular organelle part
0.37	GO:0005844	polysome
0.36	GO:0019898	extrinsic component of membrane
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0098588	bounding membrane of organelle
0.33	GO:1902493	acetyltransferase complex

0.35

EC:3.1.3

GO:0017017

sp|P47930|FOSL2_MOUSE
Fos-related antigen 2
Search

FOSL2

0.97	FOS like 2, AP-1 transcription factor subunit

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0003334	keratinocyte development
0.57	GO:0048146	positive regulation of fibroblast proliferation
0.55	GO:0006366	transcription by RNA polymerase II
0.54	GO:0045893	positive regulation of transcription, DNA-templated
0.47	GO:0035994	response to muscle stretch
0.46	GO:0045672	positive regulation of osteoclast differentiation
0.46	GO:0071277	cellular response to calcium ion
0.46	GO:0035914	skeletal muscle cell differentiation
0.46	GO:0071276	cellular response to cadmium ion

0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.55	GO:0003682	chromatin binding
0.46	GO:0070412	R-SMAD binding
0.46	GO:0001102	RNA polymerase II activating transcription factor binding
0.45	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.45	GO:0001046	core promoter sequence-specific DNA binding
0.44	GO:0000987	proximal promoter sequence-specific DNA binding
0.42	GO:0046982	protein heterodimerization activity

0.52	GO:0005654	nucleoplasm
0.47	GO:0005667	transcription factor complex
0.42	GO:0032993	protein-DNA complex
0.36	GO:0005783	endoplasmic reticulum
0.36	GO:0005829	cytosol
0.35	GO:0070552	BRISC complex
0.35	GO:0070531	BRCA1-A complex
0.35	GO:0043005	neuron projection
0.33	GO:0042025	host cell nucleus
0.30	GO:0016020	membrane

sp|P47931|FST_MOUSE
Follistatin
Search

FST

0.97	Follistatin

0.85	GO:0032926	negative regulation of activin receptor signaling pathway
0.84	GO:0051798	positive regulation of hair follicle development
0.80	GO:0002244	hematopoietic progenitor cell differentiation
0.73	GO:0000122	negative regulation of transcription by RNA polymerase II
0.44	GO:0043616	keratinocyte proliferation
0.44	GO:0031069	hair follicle morphogenesis
0.44	GO:0045596	negative regulation of cell differentiation
0.44	GO:0001501	skeletal system development
0.43	GO:0007389	pattern specification process
0.43	GO:0042475	odontogenesis of dentin-containing tooth

0.85	GO:0048185	activin binding
0.49	GO:0043395	heparan sulfate proteoglycan binding
0.36	GO:0016651	oxidoreductase activity, acting on NAD(P)H
0.36	GO:0004871	signal transducer activity

0.49	GO:0005576	extracellular region
0.37	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

0.36

EC:1.6

GO:0016651

sp|P47932|REL1_MOUSE
Prorelaxin 1
Search

0.94	Prorelaxin

0.76	GO:0010469	regulation of receptor activity
0.68	GO:0060618	nipple development
0.66	GO:0010749	regulation of nitric oxide mediated signal transduction
0.65	GO:0060736	prostate gland growth
0.63	GO:0060443	mammary gland morphogenesis
0.60	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.60	GO:0044703	multi-organism reproductive process
0.57	GO:0048609	multicellular organismal reproductive process
0.56	GO:0042981	regulation of apoptotic process
0.49	GO:0050878	regulation of body fluid levels

0.79

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

sp|P47934|CACP_MOUSE
Carnitine O-acetyltransferase
Search

CRAT

0.80	Carnitine O-acetyltransferase

0.58	GO:0019254	carnitine metabolic process, CoA-linked
0.37	GO:0006631	fatty acid metabolic process
0.34	GO:0034440	lipid oxidation
0.34	GO:0044242	cellular lipid catabolic process
0.34	GO:0072329	monocarboxylic acid catabolic process

0.63	GO:0016746	transferase activity, transferring acyl groups
0.48	GO:0005102	receptor binding

0.50	GO:0005777	peroxisome
0.44	GO:0005739	mitochondrion
0.37	GO:0005783	endoplasmic reticulum
0.35	GO:0019866	organelle inner membrane
0.35	GO:0031907	microbody lumen
0.30	GO:0031224	intrinsic component of membrane

0.63

GO:0016746

sp|P47936|CNR2_MOUSE
Cannabinoid receptor 2
Search

CNR2

0.88	Cannabinoid receptor

0.86	GO:0038171	cannabinoid signaling pathway
0.56	GO:0030595	leukocyte chemotaxis
0.48	GO:0007413	axonal fasciculation
0.47	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.46	GO:0099553	trans-synaptic signaling by endocannabinoid, modulating synaptic transmission
0.44	GO:0001889	liver development
0.42	GO:0042593	glucose homeostasis
0.42	GO:0097241	hematopoietic stem cell migration to bone marrow
0.42	GO:0060259	regulation of feeding behavior
0.41	GO:0045759	negative regulation of action potential

0.86	GO:0004949	cannabinoid receptor activity
0.35	GO:1904483	synthetic cannabinoid binding
0.35	GO:0004560	alpha-L-fucosidase activity
0.32	GO:0008144	drug binding
0.32	GO:0005515	protein binding

0.45	GO:0043005	neuron projection
0.45	GO:0005886	plasma membrane
0.44	GO:0120038	plasma membrane bounded cell projection part
0.42	GO:0030427	site of polarized growth
0.42	GO:0098793	presynapse
0.40	GO:0044297	cell body
0.39	GO:0036477	somatodendritic compartment
0.38	GO:0098562	cytoplasmic side of membrane
0.37	GO:0019898	extrinsic component of membrane
0.36	GO:0005741	mitochondrial outer membrane

0.35

EC:3.2.1.51

GO:0004560

sp|P47937|NK3R_MOUSE
Neuromedin-K receptor
Search

TACR3

0.97	Neuromedin-K receptor

0.85	GO:0007217	tachykinin receptor signaling pathway
0.58	GO:1902093	positive regulation of flagellated sperm motility
0.40	GO:0070472	regulation of uterine smooth muscle contraction
0.39	GO:0043278	response to morphine
0.39	GO:0042053	regulation of dopamine metabolic process
0.39	GO:0010460	positive regulation of heart rate
0.39	GO:0045777	positive regulation of blood pressure
0.39	GO:0045987	positive regulation of smooth muscle contraction
0.39	GO:0042220	response to cocaine
0.39	GO:0060259	regulation of feeding behavior

0.86	GO:0004995	tachykinin receptor activity
0.35	GO:0050254	rhodopsin kinase activity
0.33	GO:0005515	protein binding

0.57	GO:0097225	sperm midpiece
0.56	GO:0005886	plasma membrane
0.38	GO:0043025	neuronal cell body
0.38	GO:0030425	dendrite
0.38	GO:0031252	cell leading edge
0.37	GO:0061827	sperm head
0.35	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.35

GO:0050254

sp|P47939|RES18_MOUSE
Regulated endocrine-specific protein 18
Search

RESP18

0.97	Regulated endocrine-specific protein 18

0.80

GO:0001701

in utero embryonic development

0.70	GO:0005783	endoplasmic reticulum
0.57	GO:0005794	Golgi apparatus
0.54	GO:0005576	extracellular region
0.51	GO:0043204	perikaryon
0.49	GO:0030141	secretory granule
0.44	GO:0043233	organelle lumen
0.40	GO:0044446	intracellular organelle part

sp|P47941|CRKL_MOUSE
Crk-like protein
Search

CRKL

0.97	CRK like proto-oncogene, adaptor protein (Fragment)

0.78	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.75	GO:0060017	parathyroid gland development
0.71	GO:0048538	thymus development
0.70	GO:0009887	animal organ morphogenesis
0.68	GO:0008284	positive regulation of cell proliferation
0.67	GO:0009952	anterior/posterior pattern specification
0.66	GO:0001568	blood vessel development
0.66	GO:0007507	heart development
0.61	GO:0007520	myoblast fusion
0.55	GO:0048793	pronephros development

0.77	GO:0045309	protein phosphorylated amino acid binding
0.70	GO:0045296	cadherin binding
0.64	GO:0042802	identical protein binding
0.50	GO:0005070	SH3/SH2 adaptor activity
0.49	GO:0042169	SH2 domain binding
0.49	GO:0046875	ephrin receptor binding
0.46	GO:1990782	protein tyrosine kinase binding
0.45	GO:0043621	protein self-association
0.44	GO:0017124	SH3 domain binding
0.41	GO:0005159	insulin-like growth factor receptor binding

0.61	GO:0005654	nucleoplasm
0.60	GO:0005829	cytosol
0.44	GO:0015629	actin cytoskeleton
0.42	GO:0070062	extracellular exosome
0.40	GO:0098857	membrane microdomain
0.40	GO:0043234	protein complex
0.37	GO:0005768	endosome
0.37	GO:0031463	Cul3-RING ubiquitin ligase complex
0.34	GO:0005886	plasma membrane

sp|P47945|MT4_MOUSE
Metallothionein-4
Search

0.77	Metallothionein A

0.53	GO:0006875	cellular metal ion homeostasis
0.42	GO:0010038	response to metal ion
0.36	GO:0001525	angiogenesis
0.36	GO:0071241	cellular response to inorganic substance
0.36	GO:0045926	negative regulation of growth
0.35	GO:0051597	response to methylmercury
0.35	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis
0.35	GO:0010575	positive regulation of vascular endothelial growth factor production

0.54

GO:0046872

metal ion binding

0.36	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005829	cytosol
0.34	GO:0005634	nucleus

sp|P47955|RLA1_MOUSE
60S acidic ribosomal protein P1
Search

RPLP1

0.73	Ribosomal protein lateral stalk subunit P1

0.69	GO:0006414	translational elongation
0.50	GO:0032147	activation of protein kinase activity
0.49	GO:0002181	cytoplasmic translation
0.44	GO:0030218	erythrocyte differentiation
0.36	GO:0006417	regulation of translation
0.36	GO:1904401	cellular response to Thyroid stimulating hormone
0.35	GO:0071320	cellular response to cAMP
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0034250	positive regulation of cellular amide metabolic process
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.63	GO:0003735	structural constituent of ribosome
0.51	GO:0030295	protein kinase activator activity
0.34	GO:0043021	ribonucleoprotein complex binding
0.33	GO:0005515	protein binding
0.32	GO:0003777	microtubule motor activity
0.32	GO:0016740	transferase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0008144	drug binding

0.61	GO:0005840	ribosome
0.50	GO:0044445	cytosolic part
0.43	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016740

sp|P47962|RL5_MOUSE
60S ribosomal protein L5
Search

RPL5

0.61	Ribosomal protein L5 (Predicted)

0.60	GO:0006518	peptide metabolic process
0.60	GO:0043604	amide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:1901566	organonitrogen compound biosynthetic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.48	GO:0000027	ribosomal large subunit assembly
0.47	GO:2000435	negative regulation of protein neddylation
0.46	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.46	GO:1904667	negative regulation of ubiquitin protein ligase activity

0.79	GO:0008097	5S rRNA binding
0.64	GO:0003735	structural constituent of ribosome
0.47	GO:1990948	ubiquitin ligase inhibitor activity
0.44	GO:0003730	mRNA 3'-UTR binding
0.44	GO:0048027	mRNA 5'-UTR binding
0.43	GO:0031625	ubiquitin protein ligase binding
0.34	GO:0017048	Rho GTPase binding
0.33	GO:0016301	kinase activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0140096	catalytic activity, acting on a protein

0.61	GO:0005840	ribosome
0.45	GO:0005829	cytosol
0.44	GO:0005730	nucleolus
0.41	GO:0005783	endoplasmic reticulum
0.41	GO:0005654	nucleoplasm
0.38	GO:0043234	protein complex
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.33

GO:0016773

sp|P47963|RL13_MOUSE
60S ribosomal protein L13
Search

RPL13

0.68	Ribosomal protein L13

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.41	GO:0051726	regulation of cell cycle
0.35	GO:0097421	liver regeneration
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006508	proteolysis
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.63	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.36	GO:0004222	metalloendopeptidase activity
0.34	GO:0005515	protein binding
0.34	GO:0008270	zinc ion binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.47	GO:0005829	cytosol
0.45	GO:0005730	nucleolus
0.44	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.36

GO:0004222

sp|P47964|RL36_MOUSE
60S ribosomal protein L36
Search

RPL36

0.70	60S ribosomal protein L36 pseudogene

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.43	GO:0007420	brain development
0.42	GO:0051726	regulation of cell cycle
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process

0.62	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.35	GO:0070840	dynein complex binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0008134	transcription factor binding
0.32	GO:0016491	oxidoreductase activity

0.60	GO:0005840	ribosome
0.48	GO:0044445	cytosolic part
0.46	GO:0005844	polysome
0.43	GO:0005730	nucleolus
0.30	GO:0016020	membrane

0.32

EC:1

GO:0016491

sp|P47968|RPIA_MOUSE
Ribose-5-phosphate isomerase
Search

RPIA

0.46	Ribose 5-phosphate isomerase A

0.80	GO:0009052	pentose-phosphate shunt, non-oxidative branch
0.47	GO:0006014	D-ribose metabolic process

0.79	GO:0004751	ribose-5-phosphate isomerase activity
0.50	GO:0042802	identical protein binding
0.38	GO:0048029	monosaccharide binding

0.43	GO:0005829	cytosol
0.39	GO:0043231	intracellular membrane-bounded organelle

0.79	EC:5.3.1.6	GO:0004751
0.79	KEGG:R01056	GO:0004751

sp|P47993|XCL1_MOUSE
Lymphotactin
Search

XCL1

0.38	Viral Lymphotactin

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.69	GO:2000557	regulation of immunoglobulin production in mucosal tissue
0.69	GO:2000556	positive regulation of T-helper 1 cell cytokine production
0.68	GO:2000412	positive regulation of thymocyte migration
0.67	GO:2000537	regulation of B cell chemotaxis
0.67	GO:2000563	positive regulation of CD4-positive, alpha-beta T cell proliferation
0.66	GO:2000503	positive regulation of natural killer cell chemotaxis
0.66	GO:0072676	lymphocyte migration
0.66	GO:2000553	positive regulation of T-helper 2 cell cytokine production

0.84	GO:0008009	chemokine activity
0.54	GO:0048020	CCR chemokine receptor binding
0.44	GO:0042803	protein homodimerization activity
0.36	GO:0005153	interleukin-8 receptor binding

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane
0.30	GO:0005623	cell

sp|P48024|EIF1_MOUSE
Eukaryotic translation initiation factor 1
Search

EIF1

0.92	Eukaryotic translation initiation factor 1

0.72	GO:0006413	translational initiation
0.48	GO:0006446	regulation of translational initiation
0.45	GO:0009048	dosage compensation by inactivation of X chromosome
0.34	GO:0006886	intracellular protein transport

0.73	GO:0003743	translation initiation factor activity
0.35	GO:0017137	Rab GTPase binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0016787	hydrolase activity

0.41	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.32

GO:0016787

sp|P48025|KSYK_MOUSE
Tyrosine-protein kinase SYK
Search

SYK

0.74	Spleen associated tyrosine kinase

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.68	GO:0045399	regulation of interleukin-3 biosynthetic process
0.68	GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process
0.68	GO:0032752	positive regulation of interleukin-3 production
0.68	GO:0071226	cellular response to molecule of fungal origin
0.67	GO:0043366	beta selection
0.67	GO:0045588	positive regulation of gamma-delta T cell differentiation
0.67	GO:0002554	serotonin secretion by platelet
0.67	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation
0.67	GO:0090237	regulation of arachidonic acid secretion

0.80	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.65	GO:0035325	Toll-like receptor binding
0.64	GO:0042169	SH2 domain binding
0.64	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity
0.63	GO:0001784	phosphotyrosine residue binding
0.62	GO:0005178	integrin binding
0.61	GO:0019902	phosphatase binding
0.58	GO:0019901	protein kinase binding
0.54	GO:0004674	protein serine/threonine kinase activity
0.53	GO:0030554	adenyl nucleotide binding

0.67	GO:0019815	B cell receptor complex
0.65	GO:0032009	early phagosome
0.64	GO:0042101	T cell receptor complex
0.48	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.48	GO:0005634	nucleus

0.80

GO:0004715

sp|P48026|SAT1_MOUSE
Diamine acetyltransferase 1
Search

SAT1

0.96	Spermidine/spermine N-acetyltransferase

0.54	GO:0001525	angiogenesis
0.52	GO:0032918	spermidine acetylation
0.51	GO:0046208	spermine catabolic process
0.49	GO:0042127	regulation of cell proliferation
0.43	GO:0009447	putrescine catabolic process
0.38	GO:0032919	spermine acetylation
0.34	GO:0006596	polyamine biosynthetic process

0.85	GO:0004145	diamine N-acetyltransferase activity
0.52	GO:0019809	spermidine binding
0.50	GO:0042802	identical protein binding

0.42	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:2.3.1.57

GO:0004145

sp|P48030|TGFA_MOUSE
Protransforming growth factor alpha
Search

TGFA

0.97	Protransforming growth factor alpha

0.61	GO:0072574	hepatocyte proliferation
0.61	GO:0007173	epidermal growth factor receptor signaling pathway
0.58	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.58	GO:0060749	mammary gland alveolus development
0.58	GO:0008284	positive regulation of cell proliferation
0.55	GO:0001525	angiogenesis
0.50	GO:0000187	activation of MAPK activity
0.47	GO:0010469	regulation of receptor activity
0.45	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
0.45	GO:0051781	positive regulation of cell division

0.63	GO:0005154	epidermal growth factor receptor binding
0.48	GO:0008083	growth factor activity

0.48	GO:0005615	extracellular space
0.43	GO:0005887	integral component of plasma membrane
0.40	GO:0016323	basolateral plasma membrane
0.40	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0009986	cell surface
0.39	GO:0031410	cytoplasmic vesicle
0.37	GO:0005634	nucleus
0.37	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.35	GO:0012506	vesicle membrane
0.35	GO:0000139	Golgi membrane

sp|P48031|GBX2_MOUSE
Homeobox protein GBX-2
Search

GBX2

0.96	Gastrulation brain homeo box 2

0.62	GO:0021568	rhombomere 2 development
0.61	GO:0021555	midbrain-hindbrain boundary morphogenesis
0.60	GO:0021930	cerebellar granule cell precursor proliferation
0.59	GO:0021794	thalamus development
0.59	GO:0021953	central nervous system neuron differentiation
0.59	GO:0021549	cerebellum development
0.58	GO:0001569	branching involved in blood vessel morphogenesis
0.58	GO:0007411	axon guidance
0.58	GO:0001755	neural crest cell migration
0.57	GO:0021872	forebrain generation of neurons

0.64	GO:0043565	sequence-specific DNA binding
0.57	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.56	GO:0001047	core promoter binding
0.55	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P48036|ANXA5_MOUSE
Annexin A5
Search

ANXA5

0.57

Annexin

0.85	GO:0050819	negative regulation of coagulation
0.49	GO:0010033	response to organic substance
0.43	GO:2000145	regulation of cell motility
0.41	GO:0007596	blood coagulation
0.38	GO:0050709	negative regulation of protein secretion
0.37	GO:0032717	negative regulation of interleukin-8 production
0.37	GO:2000482	regulation of interleukin-8 secretion
0.36	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.36	GO:0007219	Notch signaling pathway
0.36	GO:0071284	cellular response to lead ion

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.37	GO:0005515	protein binding
0.36	GO:0015085	calcium ion transmembrane transporter activity
0.36	GO:0035374	chondroitin sulfate binding
0.35	GO:0017046	peptide hormone binding
0.35	GO:0004859	phospholipase inhibitor activity
0.35	GO:0008201	heparin binding
0.34	GO:0060090	molecular adaptor activity
0.34	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism

0.58	GO:0072563	endothelial microparticle
0.53	GO:0009897	external side of plasma membrane
0.39	GO:0031982	vesicle
0.38	GO:0005622	intracellular
0.38	GO:0043230	extracellular organelle
0.36	GO:0005925	focal adhesion
0.36	GO:0012505	endomembrane system
0.35	GO:0014704	intercalated disc
0.35	GO:0043204	perikaryon
0.35	GO:0043679	axon terminus

sp|P48076|PA2GC_MOUSE
Group IIC secretory phospholipase A2
Search

PLA2G2C

0.65	Group IIC secretory phospholipase A2

0.82	GO:1903963	arachidonate transport
0.82	GO:0032309	icosanoid secretion
0.72	GO:0016042	lipid catabolic process
0.67	GO:0006644	phospholipid metabolic process
0.47	GO:0042130	negative regulation of T cell proliferation
0.40	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.38	GO:0046486	glycerolipid metabolic process
0.37	GO:0009405	pathogenesis
0.37	GO:0032501	multicellular organismal process
0.36	GO:0034368	protein-lipid complex remodeling

0.84	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.84	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.82	GO:0004623	phospholipase A2 activity
0.70	GO:0005509	calcium ion binding
0.38	GO:0005543	phospholipid binding
0.38	GO:0090729	toxin activity
0.34	GO:0043395	heparan sulfate proteoglycan binding
0.33	GO:0008201	heparin binding
0.33	GO:0015446	ATPase-coupled arsenite transmembrane transporter activity
0.31	GO:0030554	adenyl nucleotide binding

0.66	GO:0005576	extracellular region
0.37	GO:0005783	endoplasmic reticulum
0.35	GO:0030141	secretory granule
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.33	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.82

EC:3.1.1.4

GO:0004623

sp|P48168|GLRB_MOUSE
Glycine receptor subunit beta
Search

GLRB

0.97	Glycine receptor subunit beta

0.77	GO:0060079	excitatory postsynaptic potential
0.75	GO:1902476	chloride transmembrane transport
0.61	GO:0060012	synaptic transmission, glycinergic
0.60	GO:0097112	gamma-aminobutyric acid receptor clustering
0.58	GO:0060013	righting reflex
0.58	GO:0001964	startle response
0.57	GO:0007628	adult walking behavior
0.57	GO:0007340	acrosome reaction
0.56	GO:0007218	neuropeptide signaling pathway
0.53	GO:0007601	visual perception

0.85	GO:0016934	extracellularly glycine-gated chloride channel activity
0.68	GO:0004888	transmembrane signaling receptor activity
0.60	GO:0016594	glycine binding
0.35	GO:0005515	protein binding
0.34	GO:0022824	transmitter-gated ion channel activity

0.77	GO:0045211	postsynaptic membrane
0.61	GO:0016935	glycine-gated chloride channel complex
0.60	GO:0098982	GABA-ergic synapse
0.39	GO:0030425	dendrite
0.38	GO:0030054	cell junction
0.35	GO:0043204	perikaryon
0.35	GO:0009897	external side of plasma membrane
0.34	GO:0005783	endoplasmic reticulum

sp|P48193|41_MOUSE
Protein 4.1
Search

EPB41

0.96	Erythrocyte membrane protein band 4.1

0.83	GO:0030866	cortical actin cytoskeleton organization
0.70	GO:1904778	positive regulation of protein localization to cell cortex
0.66	GO:0032092	positive regulation of protein binding
0.55	GO:0008360	regulation of cell shape
0.50	GO:0031032	actomyosin structure organization
0.38	GO:0006461	protein complex assembly

0.72	GO:0003779	actin binding
0.66	GO:0047485	protein N-terminus binding
0.65	GO:0051219	phosphoprotein binding
0.65	GO:0005545	1-phosphatidylinositol binding
0.64	GO:0008022	protein C-terminus binding
0.61	GO:0005198	structural molecule activity
0.40	GO:0030507	spectrin binding

0.69	GO:0005856	cytoskeleton
0.64	GO:0099738	cell cortex region
0.58	GO:0030054	cell junction
0.54	GO:0005829	cytosol
0.49	GO:0043234	protein complex
0.47	GO:0005886	plasma membrane
0.41	GO:0014069	postsynaptic density
0.39	GO:0098562	cytoplasmic side of membrane

sp|P48281|VDR_MOUSE
Vitamin D3 receptor
Search

VDR

0.97	Vitamin D receptor a

0.86	GO:0070561	vitamin D receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0038183	bile acid signaling pathway
0.57	GO:0010979	regulation of vitamin D 24-hydroxylase activity
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0045618	positive regulation of keratinocyte differentiation
0.56	GO:0010839	negative regulation of keratinocyte proliferation

0.87	GO:0008434	calcitriol receptor activity
0.79	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.59	GO:1902098	calcitriol binding
0.59	GO:1902121	lithocholic acid binding
0.58	GO:0038186	lithocholic acid receptor activity
0.56	GO:0046965	retinoid X receptor binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.51	GO:0043235	receptor complex
0.49	GO:0005667	transcription factor complex
0.46	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.37	GO:0005901	caveola
0.35	GO:0030315	T-tubule
0.35	GO:0005737	cytoplasm
0.34	GO:0005694	chromosome

0.54

EC:1.97.1

GO:0051353

sp|P48298|CCL11_MOUSE
Eotaxin
Search

0.71	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.72	GO:0010469	regulation of receptor activity
0.68	GO:0097529	myeloid leukocyte migration
0.62	GO:0071674	mononuclear cell migration
0.61	GO:0071347	cellular response to interleukin-1
0.60	GO:0006954	inflammatory response
0.60	GO:0060763	mammary duct terminal end bud growth
0.60	GO:0071356	cellular response to tumor necrosis factor
0.60	GO:0030334	regulation of cell migration

0.84	GO:0008009	chemokine activity
0.65	GO:0048020	CCR chemokine receptor binding
0.48	GO:0046983	protein dimerization activity
0.40	GO:0016004	phospholipase activator activity
0.37	GO:0004672	protein kinase activity
0.36	GO:0005153	interleukin-8 receptor binding

0.70	GO:0005615	extracellular space
0.37	GO:0005622	intracellular

sp|P48299|EDN3_MOUSE
Endothelin-3
Search

EDN3

0.94	Endothelin-3

0.85	GO:0019229	regulation of vasoconstriction
0.53	GO:0014826	vein smooth muscle contraction
0.53	GO:0003100	regulation of systemic arterial blood pressure by endothelin
0.52	GO:0008284	positive regulation of cell proliferation
0.52	GO:0030334	regulation of cell migration
0.51	GO:0010460	positive regulation of heart rate
0.51	GO:0051050	positive regulation of transport
0.51	GO:0014033	neural crest cell differentiation
0.51	GO:0014031	mesenchymal cell development
0.51	GO:0048864	stem cell development

0.53	GO:0031708	endothelin B receptor binding
0.48	GO:0005179	hormone activity
0.42	GO:0031707	endothelin A receptor binding
0.39	GO:0005125	cytokine activity
0.34	GO:0004459	L-lactate dehydrogenase activity
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.36	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.34

EC:1.1.1.27

GO:0004459

sp|P48301|TEAD2_MOUSE
Transcriptional enhancer factor TEF-4
Search

TEAD2

0.83	Transcriptional enhancer factor TEF-4

0.84	GO:0035329	hippo signaling
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0051254	positive regulation of RNA metabolic process
0.55	GO:0010557	positive regulation of macromolecule biosynthetic process
0.55	GO:0031328	positive regulation of cellular biosynthetic process
0.55	GO:0006351	transcription, DNA-templated
0.54	GO:0048368	lateral mesoderm development
0.53	GO:0048339	paraxial mesoderm development

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0001223	transcription coactivator binding
0.53	GO:0001134	transcription factor activity, transcription factor recruiting
0.53	GO:0097718	disordered domain specific binding
0.52	GO:0003677	DNA binding
0.49	GO:0046982	protein heterodimerization activity
0.47	GO:0001085	RNA polymerase II transcription factor binding
0.46	GO:0001067	regulatory region nucleic acid binding

0.58	GO:0005634	nucleus
0.50	GO:0005667	transcription factor complex
0.46	GO:0031974	membrane-enclosed lumen
0.46	GO:0005829	cytosol
0.42	GO:0044446	intracellular organelle part

sp|P48302|EDNRB_MOUSE
Endothelin B receptor
Search

EDNRB

0.96	Endothelin receptor type B

0.83	GO:0086100	endothelin receptor signaling pathway
0.81	GO:0048484	enteric nervous system development
0.79	GO:0042310	vasoconstriction
0.77	GO:0008217	regulation of blood pressure
0.61	GO:0035645	enteric smooth muscle cell differentiation
0.61	GO:0007497	posterior midgut development
0.60	GO:0014043	negative regulation of neuron maturation
0.59	GO:0050931	pigment cell differentiation
0.59	GO:0048246	macrophage chemotaxis
0.59	GO:0014821	phasic smooth muscle contraction

0.83	GO:0004962	endothelin receptor activity
0.58	GO:0017046	peptide hormone binding
0.42	GO:0031702	type 1 angiotensin receptor binding

0.43	GO:0005886	plasma membrane
0.39	GO:0098857	membrane microdomain
0.39	GO:0031965	nuclear membrane
0.30	GO:0016021	integral component of membrane

sp|P48316|GA45A_MOUSE
Growth arrest and DNA damage-inducible protein GADD45 alpha
Search

GADD45A

0.97	Growth arrest and DNA-damage-inducible protein alpha

0.72	GO:0051726	regulation of cell cycle
0.63	GO:0000185	activation of MAPKKK activity
0.63	GO:1900745	positive regulation of p38MAPK cascade
0.61	GO:0006950	response to stress
0.60	GO:0046330	positive regulation of JNK cascade
0.57	GO:0006469	negative regulation of protein kinase activity
0.57	GO:0043065	positive regulation of apoptotic process
0.56	GO:0071260	cellular response to mechanical stimulus
0.55	GO:0071479	cellular response to ionizing radiation
0.55	GO:2000379	positive regulation of reactive oxygen species metabolic process

0.56	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.55	GO:0047485	protein N-terminus binding
0.52	GO:0019900	kinase binding
0.51	GO:0042803	protein homodimerization activity
0.50	GO:0046982	protein heterodimerization activity
0.33	GO:0003735	structural constituent of ribosome

0.60	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.41	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle

sp|P48318|DCE1_MOUSE
Glutamate decarboxylase 1
Search

GAD1

0.52	Glutamate decarboxylase

0.57	GO:0019752	carboxylic acid metabolic process
0.57	GO:0035641	locomotory exploration behavior
0.56	GO:0035176	social behavior
0.46	GO:0042136	neurotransmitter biosynthetic process
0.39	GO:0016053	organic acid biosynthetic process
0.38	GO:0042493	response to drug
0.37	GO:1901566	organonitrogen compound biosynthetic process
0.36	GO:0018352	protein-pyridoxal-5-phosphate linkage
0.35	GO:0099643	signal release from synapse
0.35	GO:0099531	presynaptic process involved in chemical synaptic transmission

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.42	GO:0016595	glutamate binding
0.41	GO:0047485	protein N-terminus binding
0.39	GO:0046982	protein heterodimerization activity

0.57	GO:0060077	inhibitory synapse
0.55	GO:0043679	axon terminus
0.54	GO:0048786	presynaptic active zone
0.53	GO:0030424	axon
0.51	GO:0005938	cell cortex
0.44	GO:0005739	mitochondrion
0.36	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle
0.35	GO:0030665	clathrin-coated vesicle membrane
0.33	GO:0005886	plasma membrane

0.68

EC:4.1.1

GO:0016831

sp|P48320|DCE2_MOUSE
Glutamate decarboxylase 2
Search

GAD2

0.54	Glutamate decarboxylase

0.57	GO:0019752	carboxylic acid metabolic process
0.46	GO:0042136	neurotransmitter biosynthetic process
0.41	GO:0035641	locomotory exploration behavior
0.41	GO:0035176	social behavior
0.39	GO:0042493	response to drug
0.38	GO:0016053	organic acid biosynthetic process
0.37	GO:0016054	organic acid catabolic process
0.37	GO:1901565	organonitrogen compound catabolic process
0.36	GO:1901566	organonitrogen compound biosynthetic process
0.36	GO:0007268	chemical synaptic transmission

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.44	GO:0016595	glutamate binding
0.40	GO:0046982	protein heterodimerization activity
0.36	GO:0047485	protein N-terminus binding
0.33	GO:0070003	threonine-type peptidase activity
0.32	GO:0004175	endopeptidase activity

0.54	GO:0030424	axon
0.52	GO:0045202	synapse
0.41	GO:0099501	exocytic vesicle membrane
0.40	GO:0044306	neuron projection terminus
0.40	GO:0031225	anchored component of membrane
0.40	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0098590	plasma membrane region
0.39	GO:0005829	cytosol
0.39	GO:0030054	cell junction
0.39	GO:0005938	cell cortex

0.68

EC:4.1.1

GO:0016831

sp|P48346|IL15_MOUSE
Interleukin-15
Search

IL15

0.95	Interleukin

0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.66	GO:0035723	interleukin-15-mediated signaling pathway
0.66	GO:0045062	extrathymic T cell selection
0.66	GO:1904098	regulation of protein O-linked glycosylation
0.65	GO:0007260	tyrosine phosphorylation of STAT protein
0.65	GO:0032740	positive regulation of interleukin-17 production
0.64	GO:0032819	positive regulation of natural killer cell proliferation
0.64	GO:0060050	positive regulation of protein glycosylation
0.64	GO:0001866	NK T cell proliferation

0.80	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding

0.73	GO:0005615	extracellular space
0.59	GO:0016607	nuclear speck
0.52	GO:0005829	cytosol
0.41	GO:0009986	cell surface
0.35	GO:0005768	endosome
0.35	GO:0005794	Golgi apparatus
0.34	GO:0005887	integral component of plasma membrane

sp|P48356|LEPR_MOUSE
Leptin receptor
Search

LEPR

0.93	Transmembrane leptin receptor

0.86	GO:0033210	leptin-mediated signaling pathway
0.60	GO:0001525	angiogenesis
0.59	GO:2000505	regulation of energy homeostasis
0.59	GO:0097009	energy homeostasis
0.59	GO:0098868	bone growth
0.59	GO:0060259	regulation of feeding behavior
0.58	GO:0046850	regulation of bone remodeling
0.57	GO:0030217	T cell differentiation
0.56	GO:0006909	phagocytosis
0.56	GO:0010507	negative regulation of autophagy

0.86	GO:0038021	leptin receptor activity
0.54	GO:0042802	identical protein binding
0.39	GO:0017046	peptide hormone binding
0.37	GO:0016500	protein-hormone receptor activity

0.57	GO:0043235	receptor complex
0.44	GO:0016323	basolateral plasma membrane
0.38	GO:0005576	extracellular region
0.35	GO:0005887	integral component of plasma membrane

sp|P48377|RFX1_MOUSE
MHC class II regulatory factor RFX1
Search

RFX1

0.97	LOW QUALITY PROTEIN: MHC class II regulatory factor RFX1

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.44	GO:0006955	immune response
0.37	GO:0072560	type B pancreatic cell maturation
0.37	GO:0060284	regulation of cell development
0.37	GO:0007368	determination of left/right symmetry
0.37	GO:0120036	plasma membrane bounded cell projection organization
0.37	GO:2000026	regulation of multicellular organismal development
0.36	GO:0003351	epithelial cilium movement

0.55	GO:0003677	DNA binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005515	protein binding
0.34	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
0.34	GO:0004864	protein phosphatase inhibitor activity

0.59	GO:0005634	nucleus
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.35	GO:0005694	chromosome
0.33	GO:0005737	cytoplasm
0.32	GO:0005667	transcription factor complex
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.5

GO:0016810

sp|P48379|RFX2_MOUSE
DNA-binding protein RFX2
Search

RFX2

0.87	Regulatory factor X2

0.62	GO:0001675	acrosome assembly
0.59	GO:0060271	cilium assembly
0.59	GO:1990830	cellular response to leukemia inhibitory factor
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:1902680	positive regulation of RNA biosynthetic process
0.46	GO:0003309	type B pancreatic cell differentiation
0.45	GO:2000078	positive regulation of type B pancreatic cell development
0.45	GO:0002071	glandular epithelial cell maturation

0.61	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.40	GO:0000785	chromatin
0.39	GO:0043233	organelle lumen
0.30	GO:0016020	membrane

sp|P48381|RFX3_MOUSE
Transcription factor RFX3
Search

RFX3

0.93	Regulatory factor X, 3 (influences HLA class II expression)

0.68	GO:0072560	type B pancreatic cell maturation
0.67	GO:2000078	positive regulation of type B pancreatic cell development
0.65	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry
0.64	GO:0060285	cilium-dependent cell motility
0.61	GO:0050796	regulation of insulin secretion
0.61	GO:0060271	cilium assembly
0.57	GO:0045944	positive regulation of transcription by RNA polymerase II
0.55	GO:0045892	negative regulation of transcription, DNA-templated
0.46	GO:0006351	transcription, DNA-templated
0.43	GO:0070121	Kupffer's vesicle development

0.60	GO:0044212	transcription regulatory region DNA binding
0.52	GO:0043565	sequence-specific DNA binding
0.50	GO:0003700	DNA binding transcription factor activity
0.49	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.55	GO:0000785	chromatin
0.52	GO:0031974	membrane-enclosed lumen

sp|P48410|ABCD1_MOUSE
ATP-binding cassette sub-family D member 1
Search

ABCD1

0.86	ATP-binding cassette sub-family D member 1

0.77	GO:0006635	fatty acid beta-oxidation
0.73	GO:0000038	very long-chain fatty acid metabolic process
0.62	GO:0015910	peroxisomal long-chain fatty acid import
0.55	GO:0055085	transmembrane transport
0.54	GO:0042758	long-chain fatty acid catabolic process
0.53	GO:0032000	positive regulation of fatty acid beta-oxidation
0.50	GO:0007031	peroxisome organization
0.43	GO:0030301	cholesterol transport
0.36	GO:0036109	alpha-linolenic acid metabolic process
0.36	GO:0043651	linoleic acid metabolic process

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.62	GO:0005324	long-chain fatty acid transporter activity
0.55	GO:0042803	protein homodimerization activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0019899	enzyme binding
0.35	GO:0017154	semaphorin receptor activity
0.33	GO:0004672	protein kinase activity

0.76	GO:0005777	peroxisome
0.66	GO:0031903	microbody membrane
0.50	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0031301	integral component of organelle membrane
0.43	GO:0005739	mitochondrion
0.35	GO:0005829	cytosol

sp|P48428|TBCA_MOUSE
Tubulin-specific chaperone A
Search

TBCA

0.73	Tubulin-specific chaperone A

0.84	GO:0007021	tubulin complex assembly
0.84	GO:0007023	post-chaperonin tubulin folding pathway
0.37	GO:0007420	brain development
0.33	GO:0006886	intracellular protein transport
0.33	GO:0016192	vesicle-mediated transport
0.32	GO:0006413	translational initiation

0.84	GO:0048487	beta-tubulin binding
0.34	GO:0051087	chaperone binding
0.34	GO:0003723	RNA binding

0.72	GO:0005874	microtubule
0.48	GO:0005737	cytoplasm
0.45	GO:0005730	nucleolus
0.36	GO:0070062	extracellular exosome
0.33	GO:0048475	coated membrane
0.32	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

sp|P48432|SOX2_MOUSE
Transcription factor SOX-2
Search

SOX2

0.96	Sex-determining region Y box 2

0.59	GO:0021536	diencephalon development
0.59	GO:0035270	endocrine system development
0.58	GO:0001714	endodermal cell fate specification
0.58	GO:0048839	inner ear development
0.57	GO:0048732	gland development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0001654	eye development
0.56	GO:0010468	regulation of gene expression
0.56	GO:0035019	somatic stem cell population maintenance

0.56	GO:0035198	miRNA binding
0.55	GO:0003677	DNA binding
0.51	GO:0001067	regulatory region nucleic acid binding
0.47	GO:0003700	DNA binding transcription factor activity
0.44	GO:0003682	chromatin binding
0.37	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.47	GO:0005829	cytosol
0.47	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.38	GO:0005667	transcription factor complex

sp|P48437|PROX1_MOUSE
Prospero homeobox protein 1
Search

PROX1

0.97	Prospero homeobox protein 1

0.65	GO:0001946	lymphangiogenesis
0.65	GO:0060849	regulation of transcription involved in lymphatic endothelial cell fate commitment
0.64	GO:0070309	lens fiber cell morphogenesis
0.64	GO:1904252	negative regulation of bile acid metabolic process
0.64	GO:2000979	positive regulation of forebrain neuron differentiation
0.64	GO:0090425	acinar cell differentiation
0.64	GO:0002194	hepatocyte cell migration
0.64	GO:0070365	hepatocyte differentiation
0.63	GO:0061114	branching involved in pancreas morphogenesis
0.63	GO:0060414	aorta smooth muscle tissue morphogenesis

0.64	GO:0050692	DBD domain binding
0.64	GO:0050693	LBD domain binding
0.62	GO:0016922	ligand-dependent nuclear receptor binding
0.58	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.58	GO:0001046	core promoter sequence-specific DNA binding
0.57	GO:0003714	transcription corepressor activity
0.49	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.54	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm

sp|P48441|IDUA_MOUSE
Alpha-L-iduronidase
Search

IDUA

0.97	Alpha-L-iduronidase

0.62	GO:0030209	dermatan sulfate catabolic process
0.60	GO:0005975	carbohydrate metabolic process
0.38	GO:0007040	lysosome organization
0.38	GO:0035108	limb morphogenesis
0.38	GO:0048705	skeletal system morphogenesis
0.37	GO:0000902	cell morphogenesis
0.36	GO:0048878	chemical homeostasis
0.36	GO:0030207	chondroitin sulfate catabolic process

0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.38	GO:0005102	receptor binding

0.41	GO:0005764	lysosome
0.38	GO:0030135	coated vesicle
0.37	GO:0070062	extracellular exosome
0.36	GO:0005775	vacuolar lumen

0.66

EC:3.2.1

GO:0004553

sp|P48453|PP2BB_MOUSE
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform
Search

PPP3CB

0.50	Serine/threonine-protein phosphatase

0.71	GO:0006470	protein dephosphorylation
0.57	GO:0001915	negative regulation of T cell mediated cytotoxicity
0.56	GO:0031987	locomotion involved in locomotory behavior
0.56	GO:0035690	cellular response to drug
0.55	GO:0033173	calcineurin-NFAT signaling cascade
0.55	GO:0001946	lymphangiogenesis
0.55	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
0.54	GO:0043029	T cell homeostasis
0.54	GO:0035176	social behavior
0.53	GO:0030217	T cell differentiation

0.72	GO:0004721	phosphoprotein phosphatase activity
0.62	GO:0030346	protein phosphatase 2B binding
0.55	GO:0005516	calmodulin binding
0.50	GO:0005509	calcium ion binding
0.46	GO:0046983	protein dimerization activity
0.42	GO:0008144	drug binding
0.35	GO:0019855	calcium channel inhibitor activity

0.61	GO:0005955	calcineurin complex
0.54	GO:0030315	T-tubule
0.53	GO:0030018	Z disc
0.36	GO:0005829	cytosol
0.35	GO:0043204	perikaryon
0.34	GO:0030424	axon
0.34	GO:0005654	nucleoplasm
0.33	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.72

EC:3.1.3.16

GO:0004721

sp|P48455|PP2BC_MOUSE
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform
Search

PPP3CC

0.51	Serine/threonine-protein phosphatase

0.70	GO:0006470	protein dephosphorylation
0.41	GO:0072375	medium-term memory
0.41	GO:0071731	response to nitric oxide
0.40	GO:0007420	brain development
0.40	GO:0030431	sleep
0.38	GO:0048583	regulation of response to stimulus
0.37	GO:0002682	regulation of immune system process
0.36	GO:1904951	positive regulation of establishment of protein localization
0.36	GO:0051050	positive regulation of transport
0.35	GO:1903829	positive regulation of cellular protein localization

0.71	GO:0004721	phosphoprotein phosphatase activity
0.38	GO:0005516	calmodulin binding
0.35	GO:0016018	cyclosporin A binding
0.34	GO:0046872	metal ion binding
0.33	GO:0019899	enzyme binding
0.33	GO:0046873	metal ion transmembrane transporter activity
0.33	GO:0046983	protein dimerization activity
0.32	GO:0003676	nucleic acid binding

0.39	GO:0070062	extracellular exosome
0.36	GO:0005955	calcineurin complex
0.35	GO:0044456	synapse part
0.35	GO:0005829	cytosol
0.34	GO:0030018	Z disc
0.34	GO:0070382	exocytic vesicle
0.34	GO:0005739	mitochondrion
0.33	GO:0097458	neuron part
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.71

EC:3.1.3.16

GO:0004721

sp|P48540|GDNF_MOUSE
Glial cell line-derived neurotrophic factor
Search

GDNF

0.97	Glial cell line-derived neurotrophic factor

0.75	GO:0010469	regulation of receptor activity
0.62	GO:0021784	postganglionic parasympathetic fiber development
0.61	GO:0072107	positive regulation of ureteric bud formation
0.61	GO:0051940	regulation of catecholamine uptake involved in synaptic transmission
0.61	GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
0.60	GO:0032225	regulation of synaptic transmission, dopaminergic
0.60	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
0.60	GO:0060676	ureteric bud formation
0.60	GO:0030432	peristalsis
0.60	GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis

0.78	GO:0008083	growth factor activity
0.53	GO:0042803	protein homodimerization activity
0.37	GO:0030116	glial cell-derived neurotrophic factor receptor binding
0.36	GO:0019899	enzyme binding
0.36	GO:0005160	transforming growth factor beta receptor binding

0.66	GO:0005576	extracellular region
0.35	GO:0043235	receptor complex
0.32	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|P48542|KCNJ6_MOUSE
G protein-activated inward rectifier potassium channel 2
Search

KCNJ6

0.97	G protein-activated inward rectifier potassium channel 2

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.41	GO:0098660	inorganic ion transmembrane transport
0.38	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential
0.37	GO:0086091	regulation of heart rate by cardiac conduction
0.37	GO:0098739	import across plasma membrane
0.36	GO:0071315	cellular response to morphine
0.35	GO:0051602	response to electrical stimulus

0.86	GO:0015467	G-protein activated inward rectifier potassium channel activity
0.38	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
0.35	GO:0001965	G-protein alpha-subunit binding

0.43	GO:0005887	integral component of plasma membrane
0.37	GO:0034705	potassium channel complex
0.35	GO:0032809	neuronal cell body membrane
0.35	GO:0005794	Golgi apparatus
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon
0.34	GO:0009986	cell surface

sp|P48543|KCNJ9_MOUSE
G protein-activated inward rectifier potassium channel 3
Search

KCNJ9

0.93	G protein-activated inward rectifier potassium channel 3

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.41	GO:0098660	inorganic ion transmembrane transport
0.35	GO:0071315	cellular response to morphine
0.35	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential
0.34	GO:0051602	response to electrical stimulus
0.34	GO:0086091	regulation of heart rate by cardiac conduction
0.34	GO:0098739	import across plasma membrane

0.86	GO:0015467	G-protein activated inward rectifier potassium channel activity
0.35	GO:0005515	protein binding
0.35	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization

0.43	GO:0005887	integral component of plasma membrane
0.35	GO:0034705	potassium channel complex
0.34	GO:0032809	neuronal cell body membrane
0.34	GO:0005794	Golgi apparatus
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon
0.33	GO:0009986	cell surface

sp|P48545|KCNJ5_MOUSE
G protein-activated inward rectifier potassium channel 4
Search

KCNJ5

0.97	G protein-activated inward rectifier potassium channel 4

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.59	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential
0.56	GO:0086091	regulation of heart rate by cardiac conduction
0.55	GO:0099587	inorganic ion import across plasma membrane
0.35	GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential
0.35	GO:0071315	cellular response to morphine
0.34	GO:0051602	response to electrical stimulus

0.84	GO:0015467	G-protein activated inward rectifier potassium channel activity
0.59	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
0.35	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
0.35	GO:0005515	protein binding

0.52	GO:0008076	voltage-gated potassium channel complex
0.38	GO:0030315	T-tubule
0.37	GO:0009897	external side of plasma membrane
0.34	GO:0032809	neuronal cell body membrane
0.34	GO:0005794	Golgi apparatus
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon

sp|P48614|WN10B_MOUSE
Protein Wnt-10b
Search

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.59	GO:0051885	positive regulation of timing of anagen
0.59	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration
0.58	GO:0071374	cellular response to parathyroid hormone stimulus
0.57	GO:0061430	bone trabecula morphogenesis
0.56	GO:0071320	cellular response to cAMP
0.55	GO:0045599	negative regulation of fat cell differentiation
0.55	GO:0030501	positive regulation of bone mineralization
0.55	GO:0048641	regulation of skeletal muscle tissue development

0.73	GO:0005102	receptor binding
0.47	GO:0030545	receptor regulator activity
0.36	GO:0005525	GTP binding

0.75	GO:0005578	proteinaceous extracellular matrix
0.47	GO:0005615	extracellular space
0.32	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|P48615|WNT11_MOUSE
Protein Wnt-11
Search

sp|P48678|LMNA_MOUSE
Prelamin-A/C
Search

LMNA

0.95	Lamin A/C transcript variant 1

0.61	GO:0035105	sterol regulatory element binding protein import into nucleus
0.61	GO:1903243	negative regulation of cardiac muscle hypertrophy in response to stress
0.60	GO:0090343	positive regulation of cell aging
0.59	GO:0072201	negative regulation of mesenchymal cell proliferation
0.59	GO:0055015	ventricular cardiac muscle cell development
0.58	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.58	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity
0.56	GO:0071456	cellular response to hypoxia
0.56	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.56	GO:0006998	nuclear envelope organization

0.62	GO:0005198	structural molecule activity
0.37	GO:0042802	identical protein binding
0.36	GO:0008157	protein phosphatase 1 binding
0.32	GO:0003676	nucleic acid binding

0.79	GO:0005882	intermediate filament
0.59	GO:0005652	nuclear lamina
0.54	GO:0031965	nuclear membrane
0.50	GO:0005654	nucleoplasm
0.38	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0031012	extracellular matrix
0.35	GO:0016363	nuclear matrix
0.34	GO:0005829	cytosol
0.34	GO:0019031	viral envelope

sp|P48722|HS74L_MOUSE
Heat shock 70 kDa protein 4L
Search

HSPA4L

0.90	Heat shock protein 4 like

0.44	GO:0045040	protein import into mitochondrial outer membrane
0.43	GO:0051131	chaperone-mediated protein complex assembly
0.38	GO:0006986	response to unfolded protein
0.35	GO:0006457	protein folding

0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.49	GO:0005829	cytosol
0.43	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P48725|PCNT_MOUSE
Pericentrin
Search

PCNT

0.69	Pericentrin

0.64	GO:0090316	positive regulation of intracellular protein transport
0.64	GO:0007052	mitotic spindle organization
0.61	GO:0060271	cilium assembly
0.61	GO:0007165	signal transduction
0.33	GO:0000086	G2/M transition of mitotic cell cycle
0.33	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.33	GO:1990403	embryonic brain development
0.33	GO:0140056	organelle localization by membrane tethering
0.33	GO:0021772	olfactory bulb development
0.33	GO:0021696	cerebellar cortex morphogenesis

0.81	GO:0032947	protein complex scaffold activity
0.38	GO:0003677	DNA binding
0.33	GO:0005516	calmodulin binding
0.32	GO:0003779	actin binding
0.32	GO:0003723	RNA binding
0.30	GO:0003824	catalytic activity

0.67	GO:0034451	centriolar satellite
0.63	GO:0005814	centriole
0.54	GO:0005829	cytosol
0.33	GO:0000242	pericentriolar material
0.33	GO:0045171	intercellular bridge
0.32	GO:0036064	ciliary basal body
0.32	GO:0005874	microtubule
0.32	GO:0005801	cis-Golgi network
0.32	GO:0031514	motile cilium
0.30	GO:0016020	membrane

sp|P48744|NDP_MOUSE
Norrin
Search

NDP

0.97	NDP, norrin cystine knot growth factor

0.77	GO:0016055	Wnt signaling pathway
0.64	GO:0061298	retina vasculature development in camera-type eye
0.63	GO:0035426	extracellular matrix-cell signaling
0.57	GO:0051091	positive regulation of DNA binding transcription factor activity
0.56	GO:0010469	regulation of receptor activity
0.55	GO:0001890	placenta development
0.53	GO:0045893	positive regulation of transcription, DNA-templated
0.52	GO:0009653	anatomical structure morphogenesis
0.36	GO:0060135	maternal process involved in female pregnancy
0.35	GO:0007605	sensory perception of sound

0.61	GO:0005109	frizzled binding
0.59	GO:0005125	cytokine activity
0.54	GO:0042803	protein homodimerization activity
0.35	GO:0008083	growth factor activity

0.73	GO:0005615	extracellular space
0.56	GO:0031012	extracellular matrix
0.54	GO:0009986	cell surface
0.30	GO:0016020	membrane

sp|P48754|BRCA1_MOUSE
Breast cancer type 1 susceptibility protein homolog
Search

BRCA1

0.72	Breast cancer type 1 susceptibility protein homolog

0.80	GO:0085020	protein K6-linked ubiquitination
0.75	GO:0051865	protein autoubiquitination
0.65	GO:0006281	DNA repair
0.60	GO:0007049	cell cycle
0.59	GO:0006310	DNA recombination
0.58	GO:0009048	dosage compensation by inactivation of X chromosome
0.58	GO:0070512	positive regulation of histone H4-K20 methylation
0.57	GO:2000620	positive regulation of histone H4-K16 acetylation
0.56	GO:0035067	negative regulation of histone acetylation
0.56	GO:0071158	positive regulation of cell cycle arrest

0.73	GO:0004842	ubiquitin-protein transferase activity
0.63	GO:0008270	zinc ion binding
0.57	GO:0001105	RNA polymerase II transcription coactivator activity
0.55	GO:0003677	DNA binding
0.53	GO:0070063	RNA polymerase binding
0.51	GO:0031625	ubiquitin protein ligase binding
0.49	GO:0001067	regulatory region nucleic acid binding
0.42	GO:0003723	RNA binding
0.38	GO:0003682	chromatin binding
0.35	GO:0015631	tubulin binding

0.78	GO:0031436	BRCA1-BARD1 complex
0.61	GO:0005694	chromosome
0.56	GO:0070531	BRCA1-A complex
0.46	GO:0031981	nuclear lumen
0.43	GO:0030529	intracellular ribonucleoprotein complex
0.42	GO:0005886	plasma membrane
0.40	GO:0005815	microtubule organizing center
0.39	GO:0005737	cytoplasm

0.73

GO:0004842

sp|P48755|FOSL1_MOUSE
Fos-related antigen 1
Search

FOSL1

0.91	FBJ murine osteosarcoma viral oncogene homolog B

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.63	GO:0007296	vitellogenesis
0.63	GO:0061614	pri-miRNA transcription by RNA polymerase II
0.61	GO:0060674	placenta blood vessel development
0.60	GO:2000144	positive regulation of DNA-templated transcription, initiation
0.58	GO:0001701	in utero embryonic development
0.52	GO:0031668	cellular response to extracellular stimulus
0.47	GO:0051412	response to corticosterone
0.46	GO:0071277	cellular response to calcium ion
0.46	GO:0032570	response to progesterone

0.61	GO:0003700	DNA binding transcription factor activity
0.61	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0005515	protein binding
0.32	GO:0005509	calcium ion binding

0.60	GO:0005634	nucleus
0.53	GO:0031974	membrane-enclosed lumen
0.47	GO:0044446	intracellular organelle part
0.44	GO:0042734	presynaptic membrane
0.42	GO:0043005	neuron projection
0.39	GO:0005829	cytosol
0.32	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

sp|P48756|GIP_MOUSE
Gastric inhibitory polypeptide
Search

GIP

0.97	Gastric inhibitory polypeptide

0.76	GO:0010469	regulation of receptor activity
0.75	GO:0035640	exploration behavior
0.74	GO:0031018	endocrine pancreas development
0.74	GO:0019233	sensory perception of pain
0.72	GO:0007613	memory
0.72	GO:0008344	adult locomotory behavior
0.52	GO:0070094	positive regulation of glucagon secretion
0.50	GO:0010269	response to selenium ion
0.49	GO:0043950	positive regulation of cAMP-mediated signaling
0.49	GO:0048678	response to axon injury

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.46	GO:0043025	neuronal cell body
0.45	GO:0034774	secretory granule lumen
0.39	GO:0005788	endoplasmic reticulum lumen

sp|P48757|GAST_MOUSE
Gastrin
Search

GAST

0.97

Gastrin

0.75	GO:0010469	regulation of receptor activity
0.63	GO:0032094	response to food
0.51	GO:0007186	G-protein coupled receptor signaling pathway

0.78

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

sp|P48758|CBR1_MOUSE
Carbonyl reductase [NADPH] 1
Search

CBR1

0.81	Non-inducible carbony reductase

0.52	GO:0055114	oxidation-reduction process
0.51	GO:0042373	vitamin K metabolic process
0.45	GO:0050890	cognition
0.44	GO:0030855	epithelial cell differentiation
0.40	GO:0017144	drug metabolic process
0.40	GO:0042376	phylloquinone catabolic process
0.37	GO:0006692	prostanoid metabolic process
0.36	GO:1901523	icosanoid catabolic process
0.36	GO:0001542	ovulation from ovarian follicle
0.35	GO:0033574	response to testosterone

0.57	GO:0004090	carbonyl reductase (NADPH) activity
0.46	GO:0047021	15-hydroxyprostaglandin dehydrogenase (NADP+) activity
0.46	GO:0050221	prostaglandin-E2 9-reductase activity
0.45	GO:0070402	NADPH binding
0.41	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
0.37	GO:0000253	3-keto sterol reductase activity
0.33	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.42	GO:0005829	cytosol
0.42	GO:0005654	nucleoplasm
0.36	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:0005902	microvillus
0.33	GO:0005840	ribosome
0.33	GO:0005886	plasma membrane

0.57	EC:1.1.1.184	GO:0004090
0.46	KEGG:R04552	GO:0047021

sp|P48759|PTX3_MOUSE
Pentraxin-related protein PTX3
Search

PTX3

0.94	Pentraxin 3, long b

0.83	GO:1903016	negative regulation of exo-alpha-sialidase activity
0.83	GO:0052403	negative regulation by host of symbiont catalytic activity
0.83	GO:0044867	modulation by host of viral catalytic activity
0.83	GO:0044870	modulation by host of viral glycoprotein metabolic process
0.81	GO:0008228	opsonization
0.80	GO:0044793	negative regulation by host of viral process
0.79	GO:0046597	negative regulation of viral entry into host cell
0.79	GO:1903019	negative regulation of glycoprotein metabolic process
0.78	GO:0001878	response to yeast
0.76	GO:0045429	positive regulation of nitric oxide biosynthetic process

0.81	GO:0001872	(1->3)-beta-D-glucan binding
0.81	GO:0046790	virion binding
0.81	GO:0001849	complement component C1q binding
0.66	GO:0042802	identical protein binding
0.40	GO:0046872	metal ion binding

0.65	GO:0005615	extracellular space
0.42	GO:1904724	tertiary granule lumen
0.42	GO:0035580	specific granule lumen
0.35	GO:0043160	acrosomal lumen
0.30	GO:0031224	intrinsic component of membrane

sp|P48760|FOLC_MOUSE
Folylpolyglutamate synthase, mitochondrial
Search

FPGS

0.59	Folylpolyglutamate synthase

0.76	GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process
0.67	GO:0006730	one-carbon metabolic process
0.51	GO:0006536	glutamate metabolic process
0.38	GO:0008283	cell proliferation
0.38	GO:0031100	animal organ regeneration
0.37	GO:0001889	liver development
0.37	GO:0007420	brain development
0.35	GO:0046655	folic acid metabolic process
0.32	GO:0006139	nucleobase-containing compound metabolic process

0.76	GO:0004326	tetrahydrofolylpolyglutamate synthase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0008841	dihydrofolate synthase activity
0.35	GO:0046872	metal ion binding

0.45	GO:0005739	mitochondrion
0.38	GO:0031974	membrane-enclosed lumen
0.37	GO:0005829	cytosol
0.37	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.76

EC:6.3.2.17

GO:0004326

sp|P48771|CX7A2_MOUSE
Cytochrome c oxidase subunit 7A2, mitochondrial
Search

COX7A2

0.97	Cytochrome c oxidase polypeptide VIIa-liver/heart, mitochondrial

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.33	GO:0006879	cellular iron ion homeostasis
0.33	GO:0006826	iron ion transport
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity
0.33	GO:0008199	ferric iron binding
0.32	GO:0003676	nucleic acid binding

0.79	GO:0005746	mitochondrial respiratory chain
0.36	GO:0070062	extracellular exosome
0.33	GO:0045277	respiratory chain complex IV
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016676

sp|P48772|COX8B_MOUSE
Cytochrome c oxidase subunit 8B, mitochondrial
Search

COX8B

0.97	Cytochrome c oxidase polypeptide VIII-heart, mitochondrial

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.45	GO:0006119	oxidative phosphorylation
0.45	GO:0009060	aerobic respiration
0.39	GO:0042493	response to drug

0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.65	GO:0015002	heme-copper terminal oxidase activity
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.55	GO:0005751	mitochondrial respiratory chain complex IV
0.30	GO:0016021	integral component of membrane

0.65

GO:0016676

sp|P48774|GSTM5_MOUSE
Glutathione S-transferase Mu 5
Search

0.45	Glutathione S-transferase

0.60	GO:0018916	nitrobenzene metabolic process
0.57	GO:0070458	cellular detoxification of nitrogen compound
0.53	GO:0043627	response to estrogen
0.53	GO:0006749	glutathione metabolic process
0.52	GO:0042178	xenobiotic catabolic process
0.39	GO:1901687	glutathione derivative biosynthetic process
0.36	GO:0008065	establishment of blood-nerve barrier

0.77	GO:0004364	glutathione transferase activity
0.56	GO:0043295	glutathione binding
0.52	GO:0042802	identical protein binding
0.49	GO:0019899	enzyme binding
0.49	GO:0046983	protein dimerization activity
0.33	GO:0016223	beta-alanine-pyruvate transaminase activity

0.58	GO:0045171	intercellular bridge
0.56	GO:0035686	sperm fibrous sheath
0.50	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus

0.77

EC:2.5.1.18

GO:0004364

sp|P48776|T23O_MOUSE
Tryptophan 2,3-dioxygenase
Search

TDO2

0.63	Tryptophan 2,3-dioxygenase A

0.78	GO:0019441	tryptophan catabolic process to kynurenine
0.58	GO:0051289	protein homotetramerization
0.54	GO:0019442	tryptophan catabolic process to acetyl-CoA
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0033060	ocellus pigmentation
0.50	GO:0006726	eye pigment biosynthetic process
0.45	GO:0044550	secondary metabolite biosynthetic process
0.38	GO:0018130	heterocycle biosynthetic process
0.38	GO:1901362	organic cyclic compound biosynthetic process
0.38	GO:0019438	aromatic compound biosynthetic process

0.83	GO:0004833	tryptophan 2,3-dioxygenase activity
0.63	GO:0020037	heme binding
0.54	GO:0046872	metal ion binding
0.52	GO:0042802	identical protein binding
0.39	GO:0019825	oxygen binding
0.38	GO:0016597	amino acid binding
0.35	GO:0008234	cysteine-type peptidase activity

0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.83

EC:1.13.11.11

GO:0004833

sp|P48787|TNNI3_MOUSE
Troponin I, cardiac muscle
Search

TNNI3

0.89	High Mr cardiac troponin I

0.58	GO:0006941	striated muscle contraction
0.57	GO:0001980	regulation of systemic arterial blood pressure by ischemic conditions
0.56	GO:0060047	heart contraction
0.54	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling
0.54	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.53	GO:0001570	vasculogenesis
0.51	GO:0050881	musculoskeletal movement
0.51	GO:0006874	cellular calcium ion homeostasis
0.50	GO:0032780	negative regulation of ATPase activity
0.40	GO:0006940	regulation of smooth muscle contraction

0.57	GO:0031014	troponin T binding
0.55	GO:0030172	troponin C binding
0.54	GO:0019855	calcium channel inhibitor activity
0.53	GO:0048306	calcium-dependent protein binding
0.51	GO:0003779	actin binding
0.49	GO:0019901	protein kinase binding
0.49	GO:0019904	protein domain specific binding
0.48	GO:0032403	protein complex binding
0.37	GO:0046872	metal ion binding
0.33	GO:0016887	ATPase activity

0.82	GO:0005861	troponin complex
0.54	GO:0097512	cardiac myofibril
0.35	GO:0005634	nucleus
0.34	GO:0005829	cytosol

0.33

GO:0016887

sp|P48794|HYALP_MOUSE
Hyaluronidase PH-20
Search

SPAM1

0.72	Hyaluronidase

0.73	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization
0.60	GO:0005975	carbohydrate metabolic process
0.45	GO:0030214	hyaluronan catabolic process
0.45	GO:0042117	monocyte activation
0.44	GO:0010764	negative regulation of fibroblast migration
0.44	GO:2000484	positive regulation of interleukin-8 secretion
0.44	GO:0071493	cellular response to UV-B
0.44	GO:2000778	positive regulation of interleukin-6 secretion
0.44	GO:0060586	multicellular organismal iron ion homeostasis
0.44	GO:0061099	negative regulation of protein tyrosine kinase activity

0.85	GO:0004415	hyalurononglucosaminidase activity
0.45	GO:0030294	receptor signaling protein tyrosine kinase inhibitor activity
0.45	GO:0033906	hyaluronoglucuronidase activity
0.44	GO:0104005	hijacked molecular function
0.43	GO:0050431	transforming growth factor beta binding
0.43	GO:0005540	hyaluronic acid binding
0.43	GO:0001105	RNA polymerase II transcription coactivator activity
0.43	GO:0030971	receptor tyrosine kinase binding
0.33	GO:0008080	N-acetyltransferase activity

0.46	GO:0031225	anchored component of membrane
0.46	GO:0009897	external side of plasma membrane
0.44	GO:0098589	membrane region
0.43	GO:0031410	cytoplasmic vesicle
0.43	GO:0005902	microvillus
0.42	GO:0016324	apical plasma membrane
0.42	GO:0097223	sperm part
0.41	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0005764	lysosome
0.41	GO:0090575	RNA polymerase II transcription factor complex

0.85

EC:3.2.1.35

GO:0004415

sp|P48962|ADT1_MOUSE
ADP/ATP translocase 1
Search

SLC25A4

0.84	Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 4

0.57	GO:0015866	ADP transport
0.55	GO:0055085	transmembrane transport
0.54	GO:0046902	regulation of mitochondrial membrane permeability
0.53	GO:0060546	negative regulation of necroptotic process
0.51	GO:0008637	apoptotic mitochondrial changes
0.50	GO:0015867	ATP transport
0.45	GO:0010823	negative regulation of mitochondrion organization
0.44	GO:2001234	negative regulation of apoptotic signaling pathway
0.43	GO:0051051	negative regulation of transport
0.43	GO:0008284	positive regulation of cell proliferation

0.57	GO:0022857	transmembrane transporter activity
0.42	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0047429	nucleoside-triphosphate diphosphatase activity
0.33	GO:0008171	O-methyltransferase activity
0.33	GO:0003723	RNA binding

0.62	GO:0005743	mitochondrial inner membrane
0.53	GO:0043209	myelin sheath
0.46	GO:0071817	MMXD complex
0.43	GO:0042645	mitochondrial nucleoid
0.39	GO:0032592	integral component of mitochondrial membrane
0.39	GO:0098857	membrane microdomain
0.37	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:0005741	mitochondrial outer membrane
0.35	GO:0005634	nucleus

0.33

EC:3.6.1.19

GO:0047429

sp|P48964|MPIP1_MOUSE
M-phase inducer phosphatase 1
Search

CDC25A

0.96	Cell division cycle 25 homolog A

0.84	GO:1902751	positive regulation of cell cycle G2/M phase transition
0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.64	GO:0034644	cellular response to UV
0.48	GO:0051301	cell division
0.47	GO:0045931	positive regulation of mitotic cell cycle
0.44	GO:0009794	regulation of mitotic cell cycle, embryonic
0.42	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.42	GO:0007144	female meiosis I
0.42	GO:0032467	positive regulation of cytokinesis
0.42	GO:0001556	oocyte maturation

0.75	GO:0004725	protein tyrosine phosphatase activity
0.62	GO:0019901	protein kinase binding
0.59	GO:0051087	chaperone binding

0.50	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm
0.41	GO:0000922	spindle pole
0.41	GO:0005813	centrosome

0.75

GO:0004725

sp|P48967|MPIP3_MOUSE
M-phase inducer phosphatase 3
Search

CDC25C

0.78	M-phase inducer phosphatase 3

0.84	GO:1902751	positive regulation of cell cycle G2/M phase transition
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.49	GO:0000086	G2/M transition of mitotic cell cycle
0.48	GO:0045931	positive regulation of mitotic cell cycle
0.47	GO:0007276	gamete generation
0.45	GO:0009794	regulation of mitotic cell cycle, embryonic
0.44	GO:0034644	cellular response to UV
0.44	GO:0032467	positive regulation of cytokinesis
0.43	GO:0071695	anatomical structure maturation
0.43	GO:0048469	cell maturation

0.75	GO:0004725	protein tyrosine phosphatase activity
0.54	GO:0019901	protein kinase binding
0.50	GO:0050699	WW domain binding
0.42	GO:0051087	chaperone binding

0.48	GO:0016607	nuclear speck
0.43	GO:0000922	spindle pole
0.42	GO:0005813	centrosome
0.42	GO:0048471	perinuclear region of cytoplasm

0.75

GO:0004725

sp|P48972|MYBB_MOUSE
Myb-related protein B
Search

MYBL2

0.96	MYB proto-oncogene like 2

0.58	GO:0090307	mitotic spindle assembly
0.56	GO:1990830	cellular response to leukemia inhibitory factor
0.55	GO:0006366	transcription by RNA polymerase II
0.54	GO:0045944	positive regulation of transcription by RNA polymerase II
0.47	GO:0030154	cell differentiation
0.41	GO:0043525	positive regulation of neuron apoptotic process
0.36	GO:1990511	piRNA biosynthetic process
0.35	GO:0010529	negative regulation of transposition
0.35	GO:0007141	male meiosis I
0.35	GO:0051726	regulation of cell cycle

0.58	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.35	GO:0005515	protein binding
0.34	GO:0004674	protein serine/threonine kinase activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0005524	ATP binding

0.60	GO:0031523	Myb complex
0.50	GO:0005654	nucleoplasm

0.34

GO:0004674

sp|P48985|ATOH1_MOUSE
Protein atonal homolog 1
Search

ATOH1

0.97	Atonal bHLH transcription factor 1

0.82	GO:0042491	inner ear auditory receptor cell differentiation
0.71	GO:0045609	positive regulation of inner ear auditory receptor cell differentiation
0.70	GO:0060120	inner ear receptor cell fate commitment
0.70	GO:0048664	neuron fate determination
0.68	GO:0072148	epithelial cell fate commitment
0.65	GO:0048665	neuron fate specification
0.63	GO:0021987	cerebral cortex development
0.63	GO:0042472	inner ear morphogenesis
0.63	GO:0001764	neuron migration
0.62	GO:0007219	Notch signaling pathway

0.68	GO:0046983	protein dimerization activity
0.63	GO:0031490	chromatin DNA binding
0.62	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.61	GO:0043565	sequence-specific DNA binding
0.60	GO:0001012	RNA polymerase II regulatory region DNA binding
0.56	GO:0003690	double-stranded DNA binding
0.30	GO:0003824	catalytic activity

0.49

GO:0005634

nucleus

sp|P48986|NDF6_MOUSE
Neurogenic differentiation factor 6
Search

NEUROD6

0.93	Neurogenic differentiation factor

0.74	GO:0007399	nervous system development
0.70	GO:0030154	cell differentiation
0.57	GO:0006355	regulation of transcription, DNA-templated
0.57	GO:0060322	head development
0.56	GO:0006351	transcription, DNA-templated
0.55	GO:0048513	animal organ development
0.54	GO:1903508	positive regulation of nucleic acid-templated transcription
0.53	GO:0010628	positive regulation of gene expression
0.47	GO:0090128	regulation of synapse maturation
0.46	GO:0060284	regulation of cell development

0.68	GO:0046983	protein dimerization activity
0.58	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.58	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.42	GO:0003712	transcription cofactor activity
0.41	GO:0001102	RNA polymerase II activating transcription factor binding
0.41	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.39	GO:0003682	chromatin binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0008484	sulfuric ester hydrolase activity

0.59	GO:0005634	nucleus
0.39	GO:0005667	transcription factor complex
0.35	GO:0044446	intracellular organelle part
0.34	GO:0005737	cytoplasm
0.33	GO:0070013	intracellular organelle lumen

0.33

GO:0008484

sp|P48997|INVO_MOUSE
Involucrin
Search

IVL

0.95	Involucrin

0.85	GO:0030216	keratinocyte differentiation
0.39	GO:0010224	response to UV-B
0.39	GO:0018149	peptide cross-linking

0.38	GO:0030674	protein binding, bridging
0.35	GO:0005198	structural molecule activity

0.85	GO:0001533	cornified envelope
0.40	GO:0005737	cytoplasm
0.39	GO:0070062	extracellular exosome

sp|P48999|LOX5_MOUSE
Arachidonate 5-lipoxygenase
Search

ALOX5

0.97	Arachidonate 5-lipoxygenase a

0.60	GO:0019370	leukotriene biosynthetic process
0.58	GO:0002540	leukotriene production involved in inflammatory response
0.53	GO:0055114	oxidation-reduction process
0.40	GO:0033559	unsaturated fatty acid metabolic process
0.39	GO:0019372	lipoxygenase pathway
0.38	GO:0001676	long-chain fatty acid metabolic process
0.36	GO:0035655	interleukin-18-mediated signaling pathway
0.36	GO:0055093	response to hyperoxia
0.36	GO:0045907	positive regulation of vasoconstriction
0.36	GO:0043312	neutrophil degranulation

0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.62	GO:0005506	iron ion binding
0.38	GO:0004464	leukotriene-C4 synthase activity
0.38	GO:0008391	arachidonic acid monooxygenase activity
0.36	GO:0005515	protein binding
0.34	GO:0004984	olfactory receptor activity
0.33	GO:0005509	calcium ion binding

0.60	GO:0005641	nuclear envelope lumen
0.58	GO:0016363	nuclear matrix
0.55	GO:0031965	nuclear membrane
0.50	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0005615	extracellular space
0.36	GO:0034774	secretory granule lumen
0.36	GO:0042383	sarcolemma
0.35	GO:0030425	dendrite

0.75	EC:1.13.11	GO:0016702
0.38	KEGG:R03059	GO:0004464

sp|P49003|BMP5_MOUSE
Bone morphogenetic protein 5
Search

BMP5

0.97	Bone morphogenetic protein 5

0.73	GO:0010469	regulation of receptor activity
0.64	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.63	GO:0032347	regulation of aldosterone biosynthetic process
0.61	GO:0003323	type B pancreatic cell development
0.61	GO:0032345	negative regulation of aldosterone metabolic process
0.61	GO:2000065	negative regulation of cortisol biosynthetic process
0.60	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway
0.59	GO:2000105	positive regulation of DNA-dependent DNA replication
0.58	GO:0050679	positive regulation of epithelial cell proliferation
0.58	GO:1900006	positive regulation of dendrite development

0.76	GO:0008083	growth factor activity
0.63	GO:0070700	BMP receptor binding
0.48	GO:0005160	transforming growth factor beta receptor binding
0.46	GO:0005125	cytokine activity
0.39	GO:0046982	protein heterodimerization activity

0.65	GO:0005576	extracellular region
0.37	GO:0031982	vesicle
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P49025|CTRO_MOUSE
Citron Rho-interacting kinase
Search

CIT

0.95	Citron Rho-interacting kinase

0.75	GO:0000281	mitotic cytokinesis
0.62	GO:0035556	intracellular signal transduction
0.61	GO:0006468	protein phosphorylation
0.56	GO:0051402	neuron apoptotic process
0.55	GO:0032467	positive regulation of cytokinesis
0.41	GO:0044772	mitotic cell cycle phase transition
0.41	GO:0044784	metaphase/anaphase transition of cell cycle
0.41	GO:0044839	cell cycle G2/M phase transition
0.41	GO:0050774	negative regulation of dendrite morphogenesis
0.40	GO:0007030	Golgi organization

0.68	GO:0004674	protein serine/threonine kinase activity
0.56	GO:0097110	scaffold protein binding
0.55	GO:0030165	PDZ domain binding
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0046872	metal ion binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0017048	Rho GTPase binding
0.36	GO:0017124	SH3 domain binding
0.35	GO:0004713	protein tyrosine kinase activity

0.45	GO:0005622	intracellular
0.41	GO:0097610	cell surface furrow
0.40	GO:0030496	midbody
0.40	GO:0032155	cell division site part
0.40	GO:0043025	neuronal cell body
0.39	GO:0001726	ruffle
0.37	GO:0012505	endomembrane system
0.36	GO:0043227	membrane-bounded organelle
0.35	GO:0044422	organelle part
0.35	GO:0043228	non-membrane-bounded organelle

0.68

GO:0004674

sp|P49070|CAMLG_MOUSE
Calcium signal-modulating cyclophilin ligand
Search

CAMLG

0.97	Calcium signal-modulating cyclophilin ligand

0.56	GO:0001881	receptor recycling
0.55	GO:0007173	epidermal growth factor receptor signaling pathway
0.35	GO:0006952	defense response
0.34	GO:0016032	viral process

0.40

GO:0050839

cell adhesion molecule binding

0.54	GO:0005783	endoplasmic reticulum
0.30	GO:0044425	membrane part

sp|P49117|NR2C2_MOUSE
Nuclear receptor subfamily 2 group C member 2
Search

NR2C2

0.85	Nuclear receptor subfamily 2 group C member 2

0.79	GO:0043401	steroid hormone mediated signaling pathway
0.67	GO:0030522	intracellular receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.39	GO:0048522	positive regulation of cellular process
0.39	GO:0010557	positive regulation of macromolecule biosynthetic process
0.38	GO:0051173	positive regulation of nitrogen compound metabolic process
0.38	GO:0048385	regulation of retinoic acid receptor signaling pathway

0.80	GO:0003707	steroid hormone receptor activity
0.68	GO:0004879	nuclear receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.42	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.42	GO:0001012	RNA polymerase II regulatory region DNA binding
0.40	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.40	GO:0003690	double-stranded DNA binding
0.39	GO:0046983	protein dimerization activity
0.38	GO:0042826	histone deacetylase binding

0.61	GO:0005634	nucleus
0.40	GO:0043233	organelle lumen
0.38	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P49135|ERCC3_MOUSE
TFIIH basal transcription factor complex helicase XPB subunit
Search

ERCC3

0.88	General transcription and DNA repair factor IIH helicase subunit XPB

0.76	GO:0006367	transcription initiation from RNA polymerase II promoter
0.70	GO:0006289	nucleotide-excision repair
0.68	GO:0032392	DNA geometric change
0.60	GO:0009650	UV protection
0.59	GO:0035315	hair cell differentiation
0.55	GO:0006915	apoptotic process
0.55	GO:1901990	regulation of mitotic cell cycle phase transition
0.54	GO:0043065	positive regulation of apoptotic process
0.53	GO:0045944	positive regulation of transcription by RNA polymerase II
0.52	GO:0006265	DNA topological change

0.70	GO:0004003	ATP-dependent DNA helicase activity
0.59	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.59	GO:0047485	protein N-terminus binding
0.57	GO:0008022	protein C-terminus binding
0.56	GO:0043138	3'-5' DNA helicase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0003677	DNA binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0008134	transcription factor binding

0.58	GO:0005675	holo TFIIH complex
0.55	GO:0005669	transcription factor TFIID complex
0.38	GO:0000439	core TFIIH complex
0.34	GO:0005576	extracellular region
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.59

EC:2.7.11.23

GO:0008353

sp|P49138|MAPK2_MOUSE
MAP kinase-activated protein kinase 2
Search

MAPKAPK2

0.88	Mitogen-activated protein kinase-activated protein kinase 2

0.63	GO:0006468	protein phosphorylation
0.62	GO:0044351	macropinocytosis
0.60	GO:0070935	3'-UTR-mediated mRNA stabilization
0.59	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process
0.58	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.58	GO:0018209	peptidyl-serine modification
0.58	GO:0002224	toll-like receptor signaling pathway
0.58	GO:0032496	response to lipopolysaccharide
0.57	GO:0035924	cellular response to vascular endothelial growth factor stimulus
0.57	GO:0032675	regulation of interleukin-6 production

0.64	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0051019	mitogen-activated protein kinase binding
0.51	GO:0010857	calcium-dependent protein kinase activity
0.48	GO:0005516	calmodulin binding
0.42	GO:0004871	signal transducer activity

0.53	GO:0005813	centrosome
0.51	GO:0005654	nucleoplasm
0.40	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.64

GO:0004674

sp|P49182|HEP2_MOUSE
Heparin cofactor 2
Search

SERPIND1

0.97	Heparin cofactor 2

0.71	GO:0007596	blood coagulation
0.66	GO:0010951	negative regulation of endopeptidase activity
0.37	GO:0043687	post-translational protein modification
0.36	GO:0006935	chemotaxis

0.68	GO:0004867	serine-type endopeptidase inhibitor activity
0.44	GO:0008201	heparin binding

0.73	GO:0005615	extracellular space
0.40	GO:1903561	extracellular vesicle
0.37	GO:0005788	endoplasmic reticulum lumen

sp|P49183|DNAS1_MOUSE
Deoxyribonuclease-1
Search

DNASE1

0.64	Deoxyribonuclease

0.76	GO:0006308	DNA catabolic process
0.60	GO:0070948	regulation of neutrophil mediated cytotoxicity
0.58	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.58	GO:0002283	neutrophil activation involved in immune response
0.57	GO:0002673	regulation of acute inflammatory response
0.49	GO:0003335	corneocyte development
0.46	GO:0001942	hair follicle development
0.43	GO:0006915	apoptotic process
0.35	GO:0010623	programmed cell death involved in cell development
0.34	GO:0022411	cellular component disassembly

0.71	GO:0004536	deoxyribonuclease activity
0.60	GO:0004519	endonuclease activity
0.42	GO:0003779	actin binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0003677	DNA binding

0.42	GO:0005634	nucleus
0.41	GO:0012505	endomembrane system
0.40	GO:0005576	extracellular region
0.39	GO:0031967	organelle envelope
0.36	GO:0031982	vesicle
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P49194|RET3_MOUSE
Retinol-binding protein 3
Search

0.10	Retinol-binding protein 3

0.30	GO:0006807	nitrogen compound metabolic process
0.30	GO:0050877	nervous system process
0.30	GO:0044238	primary metabolic process
0.30	GO:0043170	macromolecule metabolic process

0.30	GO:0043178	alcohol binding
0.30	GO:0016918	retinal binding
0.30	GO:0140096	catalytic activity, acting on a protein
0.30	GO:0016787	hydrolase activity

0.30	GO:0033165	interphotoreceptor matrix
0.30	GO:0005615	extracellular space
0.30	GO:0044420	extracellular matrix component

0.30

GO:0016787

sp|P49222|EPB42_MOUSE
Erythrocyte membrane protein band 4.2
Search

EPB42

0.96	Erythrocyte membrane protein band 4.2

0.84	GO:0018149	peptide cross-linking
0.60	GO:0020027	hemoglobin metabolic process
0.59	GO:0048536	spleen development
0.54	GO:0055065	metal ion homeostasis
0.53	GO:0009653	anatomical structure morphogenesis
0.51	GO:0048869	cellular developmental process
0.47	GO:0072378	blood coagulation, fibrin clot formation
0.45	GO:0016043	cellular component organization
0.43	GO:0043277	apoptotic cell clearance
0.42	GO:0007431	salivary gland development

0.84	GO:0003810	protein-glutamine gamma-glutamyltransferase activity
0.35	GO:0005200	structural constituent of cytoskeleton
0.35	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0008483	transaminase activity
0.32	GO:0032550	purine ribonucleoside binding

0.56	GO:0030863	cortical cytoskeleton
0.39	GO:0005783	endoplasmic reticulum
0.39	GO:0005829	cytosol
0.38	GO:0031226	intrinsic component of plasma membrane
0.37	GO:0005739	mitochondrion
0.34	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.33	GO:0005925	focal adhesion
0.33	GO:0070062	extracellular exosome
0.33	GO:0031012	extracellular matrix

0.84

EC:2.3.2.13

GO:0003810

sp|P49282|NRAM2_MOUSE
Natural resistance-associated macrophage protein 2
Search

SLC11A2

0.88	Natural resistance-associated macrophage protein 2

0.66	GO:0030001	metal ion transport
0.49	GO:0060586	multicellular organismal iron ion homeostasis
0.48	GO:0048821	erythrocyte development
0.47	GO:0010039	response to iron ion
0.47	GO:0048813	dendrite morphogenesis
0.46	GO:0007611	learning or memory
0.43	GO:0072511	divalent inorganic cation transport
0.43	GO:0006783	heme biosynthetic process
0.42	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.40	GO:1902600	hydrogen ion transmembrane transport

0.69	GO:0046873	metal ion transmembrane transporter activity
0.50	GO:0015094	lead ion transmembrane transporter activity
0.49	GO:0046870	cadmium ion binding
0.45	GO:0072509	divalent inorganic cation transmembrane transporter activity
0.45	GO:0015295	solute:proton symporter activity
0.42	GO:0070835	chromium ion transmembrane transporter activity
0.36	GO:0050897	cobalt ion binding
0.36	GO:0016151	nickel cation binding
0.35	GO:0030145	manganese ion binding
0.35	GO:0005507	copper ion binding

0.50	GO:0070826	paraferritin complex
0.48	GO:0031526	brush border membrane
0.47	GO:0045178	basal part of cell
0.46	GO:0031902	late endosome membrane
0.46	GO:0055037	recycling endosome
0.46	GO:0005765	lysosomal membrane
0.46	GO:0016324	apical plasma membrane
0.46	GO:1903561	extracellular vesicle
0.46	GO:0005769	early endosome
0.45	GO:0048471	perinuclear region of cytoplasm

sp|P49290|PERE_MOUSE
Eosinophil peroxidase
Search

MPO

0.94	Eosinophil peroxidase

0.72	GO:0006952	defense response
0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.64	GO:0002148	hypochlorous acid metabolic process
0.58	GO:0018969	thiocyanate metabolic process
0.58	GO:1903409	reactive oxygen species biosynthetic process
0.55	GO:0032714	negative regulation of interleukin-5 production
0.55	GO:0009617	response to bacterium
0.54	GO:0072677	eosinophil migration
0.54	GO:0032693	negative regulation of interleukin-10 production

0.72	GO:0004601	peroxidase activity
0.63	GO:0020037	heme binding
0.50	GO:0008201	heparin binding
0.35	GO:0046872	metal ion binding
0.35	GO:0030156	benzodiazepine receptor binding
0.34	GO:0004984	olfactory receptor activity
0.34	GO:0003682	chromatin binding

0.53	GO:0005615	extracellular space
0.52	GO:0005766	primary lysosome
0.50	GO:0030141	secretory granule
0.44	GO:0016323	basolateral plasma membrane
0.42	GO:0005634	nucleus
0.42	GO:0005739	mitochondrion
0.40	GO:1903561	extracellular vesicle
0.37	GO:0060205	cytoplasmic vesicle lumen
0.35	GO:0005775	vacuolar lumen
0.30	GO:0031224	intrinsic component of membrane

0.72	EC:1.11.1.7	GO:0004601
0.72	KEGG:R03532	GO:0004601

sp|P49300|CLC10_MOUSE
C-type lectin domain family 10 member A
Search

0.94	Macrophage galactose N-acetyl-galactosamine-specific lectin 2

0.46	GO:0031668	cellular response to extracellular stimulus
0.44	GO:0055088	lipid homeostasis
0.43	GO:0031647	regulation of protein stability
0.42	GO:0009100	glycoprotein metabolic process
0.41	GO:0002248	connective tissue replacement involved in inflammatory response wound healing
0.39	GO:0006897	endocytosis
0.36	GO:0018196	peptidyl-asparagine modification
0.36	GO:0030282	bone mineralization
0.36	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0043413	macromolecule glycosylation

0.69	GO:0030246	carbohydrate binding
0.48	GO:0042803	protein homodimerization activity
0.43	GO:0004873	asialoglycoprotein receptor activity
0.34	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.34	GO:0005886	plasma membrane
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|P49312|ROA1_MOUSE
Heterogeneous nuclear ribonucleoprotein A1
Search

HNRNPA1

0.88	Heterogeneous nuclear ribonucleoprotein A1

0.53	GO:1903936	cellular response to sodium arsenite
0.48	GO:0032211	negative regulation of telomere maintenance via telomerase
0.48	GO:0032212	positive regulation of telomere maintenance via telomerase
0.47	GO:0042149	cellular response to glucose starvation
0.47	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.45	GO:0051028	mRNA transport
0.44	GO:0008380	RNA splicing
0.44	GO:0051168	nuclear export
0.44	GO:0051170	nuclear import
0.43	GO:0006397	mRNA processing

0.59	GO:0003723	RNA binding
0.49	GO:0098505	G-rich strand telomeric DNA binding
0.44	GO:0019904	protein domain specific binding
0.38	GO:0042802	identical protein binding
0.38	GO:0036310	annealing helicase activity
0.36	GO:0008134	transcription factor binding

0.65	GO:0019013	viral nucleocapsid
0.58	GO:0030529	intracellular ribonucleoprotein complex
0.46	GO:0044428	nuclear part
0.44	GO:0031974	membrane-enclosed lumen
0.40	GO:1902494	catalytic complex
0.39	GO:0070062	extracellular exosome
0.38	GO:0030117	membrane coat
0.35	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P49429|HPPD_MOUSE
4-hydroxyphenylpyruvate dioxygenase
Search

HPD

0.58	4-hydroxyphenylpyruvate dioxygenase

0.69	GO:0009072	aromatic amino acid family metabolic process
0.53	GO:0055114	oxidation-reduction process
0.43	GO:1901606	alpha-amino acid catabolic process
0.43	GO:1901361	organic cyclic compound catabolic process
0.43	GO:0019439	aromatic compound catabolic process
0.40	GO:1902221	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process
0.38	GO:0042737	drug catabolic process
0.33	GO:0032392	DNA geometric change
0.33	GO:0006260	DNA replication

0.82	GO:0003868	4-hydroxyphenylpyruvate dioxygenase activity
0.52	GO:0046872	metal ion binding
0.45	GO:0004462	lactoylglutathione lyase activity
0.33	GO:0003678	DNA helicase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0000139	Golgi membrane
0.44	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol

0.82	EC:1.13.11.27	GO:0003868
0.45	KEGG:R02530	GO:0004462

sp|P49442|INPP_MOUSE
Inositol polyphosphate 1-phosphatase
Search

INPP1

0.95	Inositol polyphosphate 1-phosphatase

0.75	GO:0046854	phosphatidylinositol phosphorylation
0.38	GO:0016311	dephosphorylation
0.36	GO:0043647	inositol phosphate metabolic process
0.34	GO:0007268	chemical synaptic transmission
0.34	GO:0046174	polyol catabolic process
0.34	GO:0030041	actin filament polymerization
0.34	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.34	GO:0046434	organophosphate catabolic process
0.33	GO:0007165	signal transduction
0.33	GO:0044262	cellular carbohydrate metabolic process

0.43	GO:0004441	inositol-1,4-bisphosphate 1-phosphatase activity
0.36	GO:0052829	inositol-1,3,4-trisphosphate 1-phosphatase activity
0.35	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0052689	carboxylic ester hydrolase activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005829	cytosol
0.34	GO:0005885	Arp2/3 protein complex
0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.43	EC:3.1.3.57	GO:0004441
0.33	KEGG:R00630	GO:0052689

sp|P49443|PPM1A_MOUSE
Protein phosphatase 1A
Search

0.95	LOW QUALITY PROTEIN: protein phosphatase 1A

0.68	GO:0006470	protein dephosphorylation
0.58	GO:0010991	negative regulation of SMAD protein complex assembly
0.57	GO:0042347	negative regulation of NF-kappaB import into nucleus
0.55	GO:0006499	N-terminal protein myristoylation
0.55	GO:0046827	positive regulation of protein export from nucleus
0.55	GO:0030514	negative regulation of BMP signaling pathway
0.55	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.54	GO:0030177	positive regulation of Wnt signaling pathway
0.53	GO:0071560	cellular response to transforming growth factor beta stimulus
0.51	GO:0016055	Wnt signaling pathway

0.73	GO:0004722	protein serine/threonine phosphatase activity
0.69	GO:0030145	manganese ion binding
0.61	GO:0000287	magnesium ion binding
0.57	GO:0070412	R-SMAD binding
0.36	GO:0004871	signal transducer activity
0.35	GO:0008022	protein C-terminus binding
0.32	GO:0003677	DNA binding

0.48	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.42	GO:0005886	plasma membrane
0.34	GO:0034704	calcium channel complex
0.34	GO:0043005	neuron projection
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

sp|P49446|PTPRE_MOUSE
Receptor-type tyrosine-protein phosphatase epsilon
Search

PTPRE

0.81	Receptor-type tyrosine-protein phosphatase epsilon

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.47	GO:0060027	convergent extension involved in gastrulation
0.39	GO:0046627	negative regulation of insulin receptor signaling pathway
0.30	GO:0002682	regulation of immune system process
0.30	GO:0007165	signal transduction
0.30	GO:0050865	regulation of cell activation

0.75	GO:0004725	protein tyrosine phosphatase activity
0.40	GO:0019198	transmembrane receptor protein phosphatase activity
0.35	GO:0005515	protein binding

0.47	GO:0005634	nucleus
0.44	GO:0005886	plasma membrane
0.40	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.75

GO:0004725

sp|P49452|CENPC_MOUSE
Centromere protein C
Search

CENPC

0.80	Centromere protein C

0.84	GO:0051382	kinetochore assembly
0.57	GO:0000278	mitotic cell cycle
0.56	GO:0051455	attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation
0.54	GO:0051310	metaphase plate congression
0.50	GO:0000819	sister chromatid segregation
0.40	GO:0051301	cell division
0.33	GO:0034080	CENP-A containing nucleosome assembly

0.85	GO:0019237	centromeric DNA binding
0.38	GO:0005515	protein binding

0.78	GO:0000776	kinetochore
0.63	GO:0005721	pericentric heterochromatin
0.62	GO:0090543	Flemming body
0.61	GO:0000780	condensed nuclear chromosome, centromeric region
0.60	GO:0032154	cleavage furrow
0.60	GO:0045171	intercellular bridge
0.56	GO:0016604	nuclear body
0.52	GO:0005720	nuclear heterochromatin
0.51	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P49582|ACHA7_MOUSE
Neuronal acetylcholine receptor subunit alpha-7
Search

CHRNA7

0.89	LOW QUALITY PROTEIN: neuronal acetylcholine receptor subunit alpha-7

0.77	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.51	GO:0035094	response to nicotine
0.49	GO:1905920	positive regulation of CoA-transferase activity
0.48	GO:0001988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure
0.48	GO:0050893	sensory processing
0.48	GO:0060112	generation of ovulation cycle rhythm
0.48	GO:0032720	negative regulation of tumor necrosis factor production
0.48	GO:0140059	dendrite arborization
0.47	GO:1905906	regulation of amyloid fibril formation

0.80	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.42	GO:0017081	chloride channel regulator activity
0.42	GO:0042166	acetylcholine binding
0.42	GO:0001540	amyloid-beta binding
0.41	GO:0015643	toxic substance binding
0.39	GO:0042803	protein homodimerization activity
0.35	GO:0008179	adenylate cyclase binding
0.35	GO:0097110	scaffold protein binding
0.35	GO:0051117	ATPase binding

0.76	GO:0045211	postsynaptic membrane
0.72	GO:0030054	cell junction
0.56	GO:0030424	axon
0.55	GO:0043204	perikaryon
0.54	GO:0120038	plasma membrane bounded cell projection part
0.53	GO:0097447	dendritic tree
0.46	GO:0005892	acetylcholine-gated channel complex
0.44	GO:0031256	leading edge membrane
0.44	GO:0009897	external side of plasma membrane
0.44	GO:0016324	apical plasma membrane

sp|P49586|PCY1A_MOUSE
Choline-phosphate cytidylyltransferase A
Search

PCYT1A

0.97	Choline-phosphate cytidylyltransferase A

0.53	GO:0006656	phosphatidylcholine biosynthetic process
0.34	GO:0001541	ovarian follicle development
0.34	GO:0007283	spermatogenesis

0.55	GO:0016779	nucleotidyltransferase activity
0.38	GO:0031210	phosphatidylcholine binding
0.37	GO:0005516	calmodulin binding
0.37	GO:0042803	protein homodimerization activity

0.56	GO:0042587	glycogen granule
0.47	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0005635	nuclear envelope
0.36	GO:0005829	cytosol
0.34	GO:0019898	extrinsic component of membrane
0.34	GO:0005886	plasma membrane

0.55

EC:2.7.7

GO:0016779

sp|P49615|CDK5_MOUSE
Cyclin-dependent-like kinase 5
Search

CDK5

0.88	Cyclin-dependent protein kinase 5

0.61	GO:0006468	protein phosphorylation
0.59	GO:0021954	central nervous system neuron development
0.58	GO:0007422	peripheral nervous system development
0.58	GO:0031914	negative regulation of synaptic plasticity
0.58	GO:1901214	regulation of neuron death
0.57	GO:0046826	negative regulation of protein export from nucleus
0.57	GO:0051402	neuron apoptotic process
0.56	GO:0022038	corpus callosum development
0.56	GO:0021819	layer formation in cerebral cortex
0.56	GO:0001963	synaptic transmission, dopaminergic

0.66	GO:0004674	protein serine/threonine kinase activity
0.59	GO:0030549	acetylcholine receptor activator activity
0.59	GO:0043125	ErbB-3 class receptor binding
0.57	GO:0005176	ErbB-2 class receptor binding
0.54	GO:0002039	p53 binding
0.53	GO:0030554	adenyl nucleotide binding
0.53	GO:0097472	cyclin-dependent protein kinase activity
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0030175	filopodium
0.54	GO:0030027	lamellipodium
0.52	GO:0030424	axon
0.52	GO:0045202	synapse
0.50	GO:0030054	cell junction
0.48	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.42	GO:0030426	growth cone
0.42	GO:0005886	plasma membrane
0.42	GO:0043025	neuronal cell body

0.66

GO:0004674

sp|P49650|P2RY1_MOUSE
P2Y purinoceptor 1
Search

P2RY1

0.97	Purinergic receptor P2Y, G-protein coupled 1

0.84	GO:0090075	relaxation of muscle
0.84	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway
0.82	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.80	GO:0030168	platelet activation
0.57	GO:0051050	positive regulation of transport
0.55	GO:0043269	regulation of ion transport
0.54	GO:0071407	cellular response to organic cyclic compound
0.45	GO:0097746	regulation of blood vessel diameter
0.44	GO:0051046	regulation of secretion
0.44	GO:0051240	positive regulation of multicellular organismal process

0.84	GO:0001608	G-protein coupled nucleotide receptor activity
0.83	GO:0001614	purinergic nucleotide receptor activity
0.43	GO:0045031	ATP-activated adenosine receptor activity
0.43	GO:0045032	ADP-activated adenosine receptor activity
0.43	GO:0031686	A1 adenosine receptor binding
0.40	GO:0097110	scaffold protein binding
0.38	GO:0043531	ADP binding
0.38	GO:0046982	protein heterodimerization activity
0.37	GO:0008528	G-protein coupled peptide receptor activity
0.37	GO:0004896	cytokine receptor activity

0.44	GO:0005886	plasma membrane
0.40	GO:0014069	postsynaptic density
0.40	GO:0044297	cell body
0.39	GO:0030425	dendrite
0.39	GO:0045177	apical part of cell
0.37	GO:0009986	cell surface
0.36	GO:0005739	mitochondrion
0.33	GO:0098552	side of membrane
0.31	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.33	EC:3.1.4.11	GO:0004435
0.33	KEGG:R03435	GO:0004435

sp|P49660|SSR4_MOUSE
Somatostatin receptor type 4
Search

SSTR4

0.96	Somatostatin receptor subtype 1

0.86	GO:0038169	somatostatin receptor signaling pathway
0.77	GO:0009755	hormone-mediated signaling pathway
0.50	GO:1990830	cellular response to leukemia inhibitory factor
0.49	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.48	GO:0007218	neuropeptide signaling pathway
0.48	GO:0071396	cellular response to lipid
0.48	GO:0071407	cellular response to organic cyclic compound
0.47	GO:0008285	negative regulation of cell proliferation
0.47	GO:0007215	glutamate receptor signaling pathway
0.46	GO:0051384	response to glucocorticoid

0.86	GO:0004994	somatostatin receptor activity
0.51	GO:0042923	neuropeptide binding
0.36	GO:0005515	protein binding
0.36	GO:0017046	peptide hormone binding

0.47	GO:0043005	neuron projection
0.44	GO:0005887	integral component of plasma membrane
0.35	GO:0098802	plasma membrane receptor complex
0.35	GO:0060170	ciliary membrane
0.35	GO:0097730	non-motile cilium
0.34	GO:0005737	cytoplasm

sp|P49681|NPBW1_MOUSE
Neuropeptides B/W receptor type 1
Search

NPBWR1

0.97	Neuropeptides B and W receptor 1

0.74	GO:0007218	neuropeptide signaling pathway
0.62	GO:0038169	somatostatin receptor signaling pathway
0.56	GO:0009755	hormone-mediated signaling pathway
0.53	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.47	GO:0007268	chemical synaptic transmission
0.40	GO:0071385	cellular response to glucocorticoid stimulus
0.40	GO:0019222	regulation of metabolic process
0.39	GO:0071392	cellular response to estradiol stimulus
0.39	GO:0038003	opioid receptor signaling pathway
0.39	GO:0008285	negative regulation of cell proliferation

0.81	GO:0008188	neuropeptide receptor activity
0.54	GO:0042923	neuropeptide binding
0.44	GO:0030165	PDZ domain binding
0.39	GO:0004985	opioid receptor activity
0.39	GO:0030273	melanin-concentrating hormone receptor activity
0.34	GO:0019956	chemokine binding
0.34	GO:0017046	peptide hormone binding
0.34	GO:0004950	chemokine receptor activity
0.34	GO:0005044	scavenger receptor activity
0.33	GO:0060182	apelin receptor activity

0.49	GO:0043005	neuron projection
0.45	GO:0005887	integral component of plasma membrane
0.40	GO:0005829	cytosol
0.33	GO:0098802	plasma membrane receptor complex

0.32	EC:3.6.1.1	GO:0004427
0.32	KEGG:R00004	GO:0004427

sp|P49698|HNF4A_MOUSE
Hepatocyte nuclear factor 4-alpha
Search

HNF4A

0.94	Hepatocyte nuclear factor 4-alpha

0.79	GO:0043401	steroid hormone mediated signaling pathway
0.76	GO:0030522	intracellular receptor signaling pathway
0.59	GO:2000189	positive regulation of cholesterol homeostasis
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0055091	phospholipid homeostasis
0.57	GO:0023019	signal transduction involved in regulation of gene expression
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0070328	triglyceride homeostasis
0.56	GO:0010470	regulation of gastrulation

0.80	GO:0003707	steroid hormone receptor activity
0.78	GO:0004879	nuclear receptor activity
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.55	GO:0005504	fatty acid binding
0.55	GO:0001102	RNA polymerase II activating transcription factor binding
0.55	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.52	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.47	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm
0.33	GO:0005667	transcription factor complex

0.35

EC:3.1.2.2

GO:0016290

sp|P49710|HCLS1_MOUSE
Hematopoietic lineage cell-specific protein
Search

HCLS1

0.84	Hematopoietic cell-specific LYN substrate 1

0.83	GO:0030041	actin filament polymerization
0.65	GO:0030854	positive regulation of granulocyte differentiation
0.64	GO:0045651	positive regulation of macrophage differentiation
0.63	GO:2000107	negative regulation of leukocyte apoptotic process
0.63	GO:0042993	positive regulation of transcription factor import into nucleus
0.63	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.62	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.62	GO:0051897	positive regulation of protein kinase B signaling
0.62	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.61	GO:0030218	erythrocyte differentiation

0.71	GO:0003779	actin binding
0.61	GO:0001085	RNA polymerase II transcription factor binding
0.58	GO:0017124	SH3 domain binding
0.58	GO:0019901	protein kinase binding
0.55	GO:0032403	protein complex binding
0.33	GO:0043565	sequence-specific DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.56	GO:0005667	transcription factor complex
0.52	GO:0005829	cytosol
0.48	GO:0005634	nucleus
0.45	GO:0005886	plasma membrane
0.36	GO:0005739	mitochondrion
0.35	GO:0002102	podosome
0.35	GO:1990023	mitotic spindle midzone
0.35	GO:0001726	ruffle
0.35	GO:0030027	lamellipodium
0.34	GO:0005794	Golgi apparatus

sp|P49717|MCM4_MOUSE
DNA replication licensing factor MCM4
Search

MCM4

0.44	DNA helicase

0.74	GO:0006270	DNA replication initiation
0.69	GO:0032392	DNA geometric change
0.46	GO:0001878	response to yeast

0.69	GO:0003678	DNA helicase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0003677	DNA binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0070035	purine NTP-dependent helicase activity
0.47	GO:0008094	DNA-dependent ATPase activity
0.42	GO:0003682	chromatin binding

0.78	GO:0042555	MCM complex
0.60	GO:0005634	nucleus
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.34	GO:0005694	chromosome
0.30	GO:0016020	membrane

sp|P49718|MCM5_MOUSE
DNA replication licensing factor MCM5
Search

MCM5

0.43	DNA replication licensing factor mcm5-B

0.75	GO:0006270	DNA replication initiation
0.70	GO:0032392	DNA geometric change
0.43	GO:0043009	chordate embryonic development
0.42	GO:0043066	negative regulation of apoptotic process
0.42	GO:0000278	mitotic cell cycle
0.37	GO:0030174	regulation of DNA-dependent DNA replication initiation
0.36	GO:0051301	cell division
0.36	GO:0006788	heme oxidation
0.35	GO:0044843	cell cycle G1/S phase transition
0.33	GO:0007165	signal transduction

0.78	GO:0003688	DNA replication origin binding
0.77	GO:0003682	chromatin binding
0.70	GO:0003678	DNA helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0004392	heme oxygenase (decyclizing) activity
0.35	GO:0005515	protein binding
0.34	GO:0016887	ATPase activity
0.33	GO:0003924	GTPase activity

0.79	GO:0042555	MCM complex
0.61	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.38	GO:0005694	chromosome
0.38	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:1.14.99.3

GO:0004392

sp|P49722|PSA2_MOUSE
Proteasome subunit alpha type-2
Search

PSMA2

0.48	Proteasome endopeptidase complex

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.67	GO:0043632	modification-dependent macromolecule catabolic process
0.35	GO:0009615	response to virus
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia

0.77	GO:0004298	threonine-type endopeptidase activity
0.34	GO:0001104	RNA polymerase II transcription cofactor activity
0.33	GO:0005515	protein binding

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.57	GO:0005634	nucleus
0.51	GO:0000932	P-body
0.38	GO:0070062	extracellular exosome
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:0101002	ficolin-1-rich granule
0.35	GO:0031983	vesicle lumen
0.34	GO:0005829	cytosol
0.34	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

0.77

EC:3.4.25

GO:0004298

sp|P49749|EVX2_MOUSE
Homeobox even-skipped homolog protein 2
Search

EVX1

0.96	Homeobox even-skipped like protein 2

0.59	GO:0035108	limb morphogenesis
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.53	GO:0021521	ventral spinal cord interneuron specification
0.48	GO:0009792	embryo development ending in birth or egg hatching
0.46	GO:1902680	positive regulation of RNA biosynthetic process
0.38	GO:0033334	fin morphogenesis
0.32	GO:0006351	transcription, DNA-templated

0.62	GO:0043565	sequence-specific DNA binding
0.33	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.44	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P49764|PLGF_MOUSE
Placenta growth factor
Search

PGF

0.92	Placental growth factor

0.76	GO:0010469	regulation of receptor activity
0.58	GO:0001658	branching involved in ureteric bud morphogenesis
0.58	GO:0060688	regulation of morphogenesis of a branching structure
0.57	GO:0008284	positive regulation of cell proliferation
0.52	GO:0060754	positive regulation of mast cell chemotaxis
0.51	GO:0050930	induction of positive chemotaxis
0.50	GO:0001936	regulation of endothelial cell proliferation
0.50	GO:0045766	positive regulation of angiogenesis
0.50	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.49	GO:0001666	response to hypoxia

0.78	GO:0008083	growth factor activity
0.52	GO:0005172	vascular endothelial growth factor receptor binding
0.42	GO:0042803	protein homodimerization activity
0.42	GO:0046982	protein heterodimerization activity
0.36	GO:0008201	heparin binding

0.52	GO:0005615	extracellular space
0.30	GO:0016020	membrane

sp|P49766|VEGFB_MOUSE
Vascular endothelial growth factor B
Search

VEGFB

0.87	vascular endothelial growth factor A precursor

0.76	GO:0010469	regulation of receptor activity
0.58	GO:0001944	vasculature development
0.57	GO:0060048	cardiac muscle contraction
0.55	GO:0050927	positive regulation of positive chemotaxis
0.54	GO:0001938	positive regulation of endothelial cell proliferation
0.54	GO:0060754	positive regulation of mast cell chemotaxis
0.54	GO:0006493	protein O-linked glycosylation
0.54	GO:0007507	heart development
0.53	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.53	GO:0045766	positive regulation of angiogenesis

0.78	GO:0008083	growth factor activity
0.70	GO:0008201	heparin binding
0.57	GO:0043183	vascular endothelial growth factor receptor 1 binding
0.56	GO:0043184	vascular endothelial growth factor receptor 2 binding
0.52	GO:0042803	protein homodimerization activity
0.51	GO:0046982	protein heterodimerization activity
0.46	GO:0042056	chemoattractant activity
0.42	GO:0001968	fibronectin binding
0.42	GO:0005161	platelet-derived growth factor receptor binding
0.40	GO:0005125	cytokine activity

0.50	GO:0005576	extracellular region
0.41	GO:0030141	secretory granule
0.39	GO:0009986	cell surface
0.38	GO:0060205	cytoplasmic vesicle lumen
0.30	GO:0016020	membrane

0.35

GO:0003755

sp|P49769|PSN1_MOUSE
Presenilin-1
Search

PSEN1

0.80	Presenilin

0.81	GO:0007219	Notch signaling pathway
0.78	GO:0042987	amyloid precursor protein catabolic process
0.75	GO:0016485	protein processing
0.60	GO:0050435	amyloid-beta metabolic process
0.60	GO:0051563	smooth endoplasmic reticulum calcium ion homeostasis
0.59	GO:1904797	negative regulation of core promoter binding
0.59	GO:0006509	membrane protein ectodomain proteolysis
0.59	GO:0021870	Cajal-Retzius cell differentiation
0.59	GO:1905908	positive regulation of amyloid fibril formation
0.58	GO:0002265	astrocyte activation involved in immune response

0.77	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving
0.55	GO:0008013	beta-catenin binding
0.55	GO:0030165	PDZ domain binding
0.54	GO:0045296	cadherin binding
0.52	GO:0005262	calcium channel activity
0.34	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0003723	RNA binding

0.73	GO:0000139	Golgi membrane
0.71	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.71	GO:0098827	endoplasmic reticulum subcompartment
0.59	GO:0070765	gamma-secretase complex
0.58	GO:0005790	smooth endoplasmic reticulum
0.57	GO:0035253	ciliary rootlet
0.57	GO:0016235	aggresome
0.57	GO:0043198	dendritic shaft
0.55	GO:0030426	growth cone
0.54	GO:0098857	membrane microdomain

0.77

EC:3.4.23

GO:0042500

sp|P49772|FLT3L_MOUSE
Fms-related tyrosine kinase 3 ligand
Search

FLT3LG

0.97	Fms-related tyrosine kinase 3 ligand

0.76	GO:0010469	regulation of receptor activity
0.72	GO:0090290	positive regulation of osteoclast proliferation
0.72	GO:0071866	negative regulation of apoptotic process in bone marrow
0.71	GO:0030885	regulation of myeloid dendritic cell activation
0.71	GO:0071864	positive regulation of cell proliferation in bone marrow
0.70	GO:0032825	positive regulation of natural killer cell differentiation
0.69	GO:1901741	positive regulation of myoblast fusion
0.68	GO:0045663	positive regulation of myoblast differentiation
0.68	GO:0048873	homeostasis of number of cells within a tissue
0.67	GO:0035162	embryonic hemopoiesis

0.81	GO:0005125	cytokine activity
0.66	GO:0030971	receptor tyrosine kinase binding
0.60	GO:0042803	protein homodimerization activity
0.49	GO:0016301	kinase activity

0.68	GO:0031233	intrinsic component of external side of plasma membrane
0.58	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

sp|P49813|TMOD1_MOUSE
Tropomodulin-1
Search

TMOD1

0.89	Erythrocyte tropomodulin

0.85	GO:0051694	pointed-end actin filament capping
0.58	GO:0030239	myofibril assembly
0.58	GO:0070307	lens fiber cell development
0.56	GO:0006936	muscle contraction
0.55	GO:0008344	adult locomotory behavior
0.44	GO:0007015	actin filament organization
0.35	GO:0033275	actin-myosin filament sliding
0.35	GO:0031034	myosin filament assembly
0.35	GO:0045292	mRNA cis splicing, via spliceosome
0.34	GO:0051028	mRNA transport

0.85	GO:0005523	tropomyosin binding
0.78	GO:0051015	actin filament binding
0.35	GO:0000339	RNA cap binding
0.32	GO:0046872	metal ion binding

0.57	GO:0005865	striated muscle thin filament
0.55	GO:0005884	actin filament
0.54	GO:0008180	COP9 signalosome
0.53	GO:0030863	cortical cytoskeleton
0.38	GO:0043034	costamere
0.38	GO:0042383	sarcolemma
0.36	GO:0098723	skeletal muscle myofibril
0.35	GO:0005846	nuclear cap binding complex
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|P49817|CAV1_MOUSE
Caveolin-1
Search

CAV1

0.82

Caveolin

0.85	GO:0070836	caveola assembly
0.66	GO:0031295	T cell costimulation
0.64	GO:0031623	receptor internalization
0.63	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.62	GO:1900085	negative regulation of peptidyl-tyrosine autophosphorylation
0.62	GO:1903609	negative regulation of inward rectifier potassium channel activity
0.61	GO:0033484	nitric oxide homeostasis
0.61	GO:0086098	angiotensin-activated signaling pathway involved in heart process
0.61	GO:0060355	positive regulation of cell adhesion molecule production
0.61	GO:0048550	negative regulation of pinocytosis

0.62	GO:0070320	inward rectifier potassium channel inhibitor activity
0.60	GO:0050998	nitric-oxide synthase binding
0.58	GO:0044325	ion channel binding
0.57	GO:0048365	Rac GTPase binding
0.57	GO:0051117	ATPase binding
0.56	GO:0016504	peptidase activator activity
0.55	GO:0032947	protein complex scaffold activity
0.54	GO:0030674	protein binding, bridging
0.54	GO:0019901	protein kinase binding
0.51	GO:0042802	identical protein binding

0.84	GO:0005901	caveola
0.74	GO:0000139	Golgi membrane
0.58	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex
0.58	GO:0002080	acrosomal membrane
0.57	GO:0005768	endosome
0.55	GO:0005925	focal adhesion
0.54	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005929	cilium
0.52	GO:0005938	cell cortex
0.48	GO:0005887	integral component of plasma membrane

sp|P49891|ST1E1_MOUSE
Estrogen sulfotransferase, testis isoform
Search

0.54	Estrogen sulfotransferase, testis isoform

0.89	GO:0006711	estrogen catabolic process
0.87	GO:0006068	ethanol catabolic process
0.87	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.85	GO:0045600	positive regulation of fat cell differentiation
0.85	GO:0007565	female pregnancy
0.83	GO:0051923	sulfation

0.89	GO:0047894	flavonol 3-sulfotransferase activity
0.88	GO:0004304	estrone sulfotransferase activity
0.88	GO:0050294	steroid sulfotransferase activity
0.83	GO:0005496	steroid binding

0.56	GO:0031965	nuclear membrane
0.50	GO:0005829	cytosol

0.89	EC:2.8.2.25	GO:0047894
0.89	KEGG:R02159	GO:0047894

sp|P49919|CDN1C_MOUSE
Cyclin-dependent kinase inhibitor 1C
Search

CDKN1C

0.89	Cyclin-dependent kinase inhibitor 1C

0.84	GO:0007050	cell cycle arrest
0.82	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.73	GO:0007346	regulation of mitotic cell cycle
0.62	GO:1902746	regulation of lens fiber cell differentiation
0.59	GO:0060669	embryonic placenta morphogenesis
0.59	GO:0060065	uterus development
0.59	GO:0030325	adrenal gland development
0.59	GO:0071514	genetic imprinting
0.58	GO:0042551	neuron maturation
0.57	GO:0035264	multicellular organism growth

0.85	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.55	GO:0016301	kinase activity
0.44	GO:0005515	protein binding
0.42	GO:0044877	macromolecular complex binding

0.61	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm

sp|P49935|CATH_MOUSE
Pro-cathepsin H
Search

CTSH

0.97	Cathepsin H transcript variant 3

0.61	GO:0006508	proteolysis
0.59	GO:0010813	neuropeptide catabolic process
0.59	GO:0010815	bradykinin catabolic process
0.58	GO:0043129	surfactant homeostasis
0.57	GO:0097067	cellular response to thyroid hormone stimulus
0.57	GO:0060448	dichotomous subdivision of terminal units involved in lung branching
0.57	GO:0070371	ERK1 and ERK2 cascade
0.56	GO:0001913	T cell mediated cytotoxicity
0.56	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.56	GO:0031648	protein destabilization

0.72	GO:0008234	cysteine-type peptidase activity
0.60	GO:0030108	HLA-A specific activating MHC class I receptor activity
0.59	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.57	GO:0070324	thyroid hormone binding
0.49	GO:0004177	aminopeptidase activity
0.47	GO:0004252	serine-type endopeptidase activity
0.36	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding
0.33	GO:0043140	ATP-dependent 3'-5' DNA helicase activity
0.32	GO:0030554	adenyl nucleotide binding

0.58	GO:0097208	alveolar lamellar body
0.53	GO:0005764	lysosome
0.52	GO:0036464	cytoplasmic ribonucleoprotein granule
0.50	GO:0005615	extracellular space
0.48	GO:0005829	cytosol
0.37	GO:1903561	extracellular vesicle
0.36	GO:0097486	multivesicular body lumen
0.36	GO:0001520	outer dense fiber
0.36	GO:1904724	tertiary granule lumen
0.36	GO:1904813	ficolin-1-rich granule lumen

0.72

GO:0008234

sp|P49945|FRIL2_MOUSE
Ferritin light chain 2
Search

FTL

0.54	Ferritin light chain

0.76	GO:0006879	cellular iron ion homeostasis
0.75	GO:0006826	iron ion transport
0.57	GO:0051238	sequestering of metal ion
0.53	GO:0051651	maintenance of location in cell
0.36	GO:0010288	response to lead ion
0.35	GO:0043312	neutrophil degranulation
0.33	GO:0055114	oxidation-reduction process

0.75	GO:0008199	ferric iron binding
0.38	GO:0042802	identical protein binding
0.36	GO:0004322	ferroxidase activity
0.32	GO:0016874	ligase activity

0.49	GO:0070288	ferritin complex
0.41	GO:0044754	autolysosome
0.37	GO:0060205	cytoplasmic vesicle lumen
0.36	GO:0070062	extracellular exosome
0.35	GO:0005766	primary lysosome
0.35	GO:0005775	vacuolar lumen
0.35	GO:0030139	endocytic vesicle
0.34	GO:0030141	secretory granule
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:1.16.3.1

GO:0004322

sp|P49962|SRP09_MOUSE
Signal recognition particle 9 kDa protein
Search

SRP9

0.90	Signal recognition particle 9

0.79	GO:0045900	negative regulation of translational elongation
0.75	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.45	GO:0065002	intracellular protein transmembrane transport

0.78	GO:0008312	7S RNA binding
0.48	GO:0005047	signal recognition particle binding
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.76	GO:0048500	signal recognition particle
0.49	GO:0005785	signal recognition particle receptor complex
0.37	GO:0070062	extracellular exosome
0.35	GO:0005829	cytosol

0.32

GO:0016787

sp|P50096|IMDH1_MOUSE
Inosine-5'-monophosphate dehydrogenase 1
Search

IMPDH1

0.55	Inosine-5'-monophosphate dehydrogenase

0.76	GO:0006177	GMP biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.51	GO:0046651	lymphocyte proliferation
0.46	GO:0006183	GTP biosynthetic process
0.43	GO:0048066	developmental pigmentation
0.42	GO:0001654	eye development
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0009409	response to cold
0.33	GO:0032259	methylation

0.79	GO:0003938	IMP dehydrogenase activity
0.54	GO:0046872	metal ion binding
0.50	GO:1901265	nucleoside phosphate binding
0.49	GO:0036094	small molecule binding
0.40	GO:0003677	DNA binding
0.33	GO:0008168	methyltransferase activity
0.33	GO:0003723	RNA binding

0.59	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.35	GO:0031983	vesicle lumen
0.34	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0005576	extracellular region
0.33	GO:0044446	intracellular organelle part

0.79

EC:1.1.1.205

GO:0003938

sp|P50114|S100B_MOUSE
Protein S100-B
Search

S100B

0.40	S100 calcium binding protein B

0.53	GO:0048168	regulation of neuronal synaptic plasticity
0.52	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.52	GO:0007613	memory
0.49	GO:0050727	regulation of inflammatory response
0.48	GO:0045087	innate immune response
0.42	GO:0048708	astrocyte differentiation
0.42	GO:0031643	positive regulation of myelination
0.42	GO:0051597	response to methylmercury
0.42	GO:2001015	negative regulation of skeletal muscle cell differentiation
0.41	GO:0060291	long-term synaptic potentiation

0.70	GO:0005509	calcium ion binding
0.63	GO:0050786	RAGE receptor binding
0.63	GO:0008270	zinc ion binding
0.56	GO:0044548	S100 protein binding
0.55	GO:0048306	calcium-dependent protein binding
0.52	GO:0035662	Toll-like receptor 4 binding
0.52	GO:0050544	arachidonic acid binding
0.51	GO:0042803	protein homodimerization activity
0.48	GO:0008092	cytoskeletal protein binding
0.35	GO:0019210	kinase inhibitor activity

0.54	GO:0001726	ruffle
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0043025	neuronal cell body
0.45	GO:0005634	nucleus
0.40	GO:0005576	extracellular region
0.39	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.37	GO:0005829	cytosol
0.37	GO:0012505	endomembrane system
0.36	GO:0045178	basal part of cell
0.36	GO:0031967	organelle envelope

sp|P50136|ODBA_MOUSE
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
Search

BCKDHA

0.87	Branched chain keto acid dehydrogenase E1 alpha polypeptide

0.81	GO:0009083	branched-chain amino acid catabolic process
0.53	GO:0055114	oxidation-reduction process

0.83	GO:0003826	alpha-ketoacid dehydrogenase activity
0.83	GO:0003863	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity

0.83

EC:1.2.4.4

GO:0003863

sp|P50149|GNAT2_MOUSE
Guanine nucleotide-binding protein G(t) subunit alpha-2
Search

GNAT2

0.94	Guanine nucleotide-binding protein Gt subunit alpha-X

0.82	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.64	GO:0050908	detection of light stimulus involved in visual perception
0.60	GO:0042462	eye photoreceptor cell development
0.60	GO:0050909	sensory perception of taste
0.59	GO:0060041	retina development in camera-type eye
0.57	GO:0007602	phototransduction
0.55	GO:0048593	camera-type eye morphogenesis
0.49	GO:0050907	detection of chemical stimulus involved in sensory perception
0.47	GO:0071257	cellular response to electrical stimulus
0.44	GO:0008283	cell proliferation

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0001664	G-protein coupled receptor binding
0.37	GO:0000035	acyl binding
0.36	GO:0046872	metal ion binding
0.35	GO:0019901	protein kinase binding

0.65	GO:0001917	photoreceptor inner segment
0.63	GO:0001750	photoreceptor outer segment
0.53	GO:1905360	GTPase complex
0.52	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.46	GO:0043234	protein complex
0.46	GO:0032391	photoreceptor connecting cilium
0.41	GO:0098590	plasma membrane region
0.40	GO:0045177	apical part of cell
0.38	GO:0030141	secretory granule
0.38	GO:0097223	sperm part

sp|P50153|GBG4_MOUSE
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
Search

GNG4

0.71	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0030308	negative regulation of cell growth
0.42	GO:0008283	cell proliferation
0.42	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.42	GO:0002040	sprouting angiogenesis
0.37	GO:0071377	cellular response to glucagon stimulus
0.36	GO:0071380	cellular response to prostaglandin E stimulus
0.36	GO:0071870	cellular response to catecholamine stimulus
0.36	GO:0007040	lysosome organization
0.36	GO:0019933	cAMP-mediated signaling

0.64	GO:0004871	signal transducer activity
0.50	GO:0031681	G-protein beta-subunit binding
0.35	GO:0003924	GTPase activity

0.81	GO:1905360	GTPase complex
0.80	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.65	GO:0098797	plasma membrane protein complex
0.38	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|P50171|DHB8_MOUSE
Estradiol 17-beta-dehydrogenase 8
Search

HSD17B8

0.32	Mitochondrial/plastidial beta-ketoacyl-ACP reductase

0.56	GO:0008210	estrogen metabolic process
0.55	GO:0051290	protein heterotetramerization
0.55	GO:0008209	androgen metabolic process
0.51	GO:0042446	hormone biosynthetic process
0.50	GO:0055114	oxidation-reduction process
0.50	GO:0006694	steroid biosynthetic process
0.48	GO:0006633	fatty acid biosynthetic process
0.35	GO:0030001	metal ion transport
0.35	GO:0046949	fatty-acyl-CoA biosynthetic process
0.34	GO:0019290	siderophore biosynthetic process

0.57	GO:0047035	testosterone dehydrogenase (NAD+) activity
0.57	GO:0047025	3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity
0.57	GO:0070404	NADH binding
0.56	GO:0004303	estradiol 17-beta-dehydrogenase activity
0.49	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
0.42	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
0.38	GO:0102131	3-oxo-glutaryl-[acp] methyl ester reductase activity
0.38	GO:0102132	3-oxo-pimeloyl-[acp] methyl ester reductase activity
0.36	GO:0046873	metal ion transmembrane transporter activity
0.35	GO:0008667	2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity

0.49	GO:0005759	mitochondrial matrix
0.43	GO:0005740	mitochondrial envelope
0.41	GO:0005886	plasma membrane
0.36	GO:0035102	PRC1 complex
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.57	EC:1.1.1.239	GO:0047035
0.57	KEGG:R01836	GO:0047035

sp|P50172|DHI1_MOUSE
Corticosteroid 11-beta-dehydrogenase isozyme 1
Search

HSD11B1

0.97	Corticosteroid 11-beta-dehydrogenase isozyme 1

0.57	GO:0030324	lung development
0.52	GO:0055114	oxidation-reduction process
0.42	GO:0008202	steroid metabolic process
0.37	GO:0042445	hormone metabolic process
0.36	GO:0043456	regulation of pentose-phosphate shunt
0.36	GO:0071392	cellular response to estradiol stimulus
0.35	GO:0008610	lipid biosynthetic process
0.35	GO:0031667	response to nutrient levels
0.34	GO:0016042	lipid catabolic process
0.34	GO:1901361	organic cyclic compound catabolic process

0.63	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity
0.48	GO:0070524	11-beta-hydroxysteroid dehydrogenase (NADP+) activity
0.35	GO:0005496	steroid binding
0.34	GO:0050661	NADP binding
0.33	GO:0102132	3-oxo-pimeloyl-[acp] methyl ester reductase activity
0.33	GO:0102131	3-oxo-glutaryl-[acp] methyl ester reductase activity
0.33	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity

0.41	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0005791	rough endoplasmic reticulum
0.35	GO:0045177	apical part of cell
0.35	GO:0044428	nuclear part
0.34	GO:0031090	organelle membrane
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0031967	organelle envelope
0.30	GO:0031224	intrinsic component of membrane

0.48

EC:1.1.1.146

GO:0070524

sp|P50207|HXC13_MOUSE
Homeobox protein Hox-C13
Search

0.96	Transcription factor HoxC13

0.58	GO:0043587	tongue morphogenesis
0.58	GO:0035878	nail development
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0001942	hair follicle development
0.53	GO:0009952	anterior/posterior pattern specification
0.51	GO:0006366	transcription by RNA polymerase II
0.50	GO:1902680	positive regulation of RNA biosynthetic process
0.37	GO:2001055	positive regulation of mesenchymal cell apoptotic process

0.63	GO:0043565	sequence-specific DNA binding
0.54	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0003682	chromatin binding
0.36	GO:0035326	enhancer binding
0.35	GO:0001012	RNA polymerase II regulatory region DNA binding
0.35	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding
0.34	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding

0.60

GO:0005634

nucleus

sp|P50220|NKX21_MOUSE
Homeobox protein Nkx-2.1
Search

NKX2-1

0.89	Thyroid transcription factor 1

0.63	GO:0021536	diencephalon development
0.62	GO:0021761	limbic system development
0.59	GO:0060486	Clara cell differentiation
0.58	GO:0030878	thyroid gland development
0.58	GO:0060510	Type II pneumocyte differentiation
0.58	GO:0021798	forebrain dorsal/ventral pattern formation
0.58	GO:0060430	lung saccule development
0.58	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.58	GO:0021892	cerebral cortex GABAergic interneuron differentiation
0.58	GO:0060441	epithelial tube branching involved in lung morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.59	GO:0044213	intronic transcription regulatory region DNA binding
0.55	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.54	GO:0001047	core promoter binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.50	GO:0019899	enzyme binding
0.37	GO:0008134	transcription factor binding
0.36	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.35	GO:0042803	protein homodimerization activity

0.61	GO:0005634	nucleus
0.50	GO:0005667	transcription factor complex
0.39	GO:0070013	intracellular organelle lumen
0.36	GO:0044446	intracellular organelle part

sp|P50228|CXCL5_MOUSE
C-X-C motif chemokine 5
Search

0.73	Alveolar macrophage chemotactic factor 2

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.72	GO:0006952	defense response
0.69	GO:0010469	regulation of receptor activity
0.56	GO:0090023	positive regulation of neutrophil chemotaxis
0.54	GO:0032496	response to lipopolysaccharide
0.53	GO:0070098	chemokine-mediated signaling pathway
0.52	GO:1990266	neutrophil migration
0.50	GO:0002446	neutrophil mediated immunity
0.50	GO:0071219	cellular response to molecule of bacterial origin

0.84	GO:0008009	chemokine activity
0.55	GO:0045236	CXCR chemokine receptor binding
0.41	GO:0008201	heparin binding
0.40	GO:0042802	identical protein binding
0.35	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity
0.32	GO:0016787	hydrolase activity

0.68	GO:0005615	extracellular space
0.30	GO:0016020	membrane
0.30	GO:0005623	cell

0.35	EC:1.5.1.5	GO:0004488
0.35	KEGG:R01220	GO:0004488

sp|P50236|ST2A2_MOUSE
Bile salt sulfotransferase 2
Search

0.53	Bile salt sulfotransferase

0.53	GO:0051923	sulfation
0.50	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.49	GO:0008202	steroid metabolic process
0.48	GO:0006068	ethanol catabolic process
0.45	GO:0042403	thyroid hormone metabolic process
0.42	GO:0006805	xenobiotic metabolic process
0.41	GO:0017085	response to insecticide
0.40	GO:0014823	response to activity
0.40	GO:0071305	cellular response to vitamin D
0.39	GO:0045606	positive regulation of epidermal cell differentiation

0.78	GO:0008146	sulfotransferase activity
0.42	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding
0.39	GO:1990239	steroid hormone binding
0.38	GO:0015485	cholesterol binding
0.34	GO:0008144	drug binding
0.34	GO:0005515	protein binding
0.33	GO:0003676	nucleic acid binding
0.32	GO:0003735	structural constituent of ribosome

0.45	GO:0005829	cytosol
0.35	GO:0043227	membrane-bounded organelle
0.35	GO:0012505	endomembrane system
0.35	GO:0043230	extracellular organelle
0.34	GO:0043229	intracellular organelle
0.34	GO:0005615	extracellular space
0.33	GO:0031975	envelope
0.32	GO:0044422	organelle part
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043228	non-membrane-bounded organelle

0.78

GO:0008146

sp|P50247|SAHH_MOUSE
Adenosylhomocysteinase
Search

AHCY

0.56	Adenosylhomocysteinase A

0.77	GO:0019510	S-adenosylhomocysteine catabolic process
0.72	GO:0006730	one-carbon metabolic process
0.48	GO:0033353	S-adenosylmethionine cycle
0.38	GO:0002439	chronic inflammatory response to antigenic stimulus
0.37	GO:0042745	circadian sleep/wake cycle
0.36	GO:0071268	homocysteine biosynthetic process
0.36	GO:0001666	response to hypoxia
0.36	GO:0007584	response to nutrient
0.34	GO:0048033	heme o metabolic process
0.33	GO:0006783	heme biosynthetic process

0.80	GO:0004013	adenosylhomocysteinase activity
0.65	GO:0051287	NAD binding
0.38	GO:0043621	protein self-association
0.36	GO:0098604	adenosylselenohomocysteinase activity
0.36	GO:0005507	copper ion binding
0.35	GO:0042802	identical protein binding
0.34	GO:0008495	protoheme IX farnesyltransferase activity
0.33	GO:0030554	adenyl nucleotide binding

0.47	GO:0005829	cytosol
0.41	GO:0042470	melanosome
0.36	GO:0070062	extracellular exosome
0.36	GO:0043005	neuron projection
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.80

EC:3.3.1.1

GO:0004013

sp|P50283|CD7_MOUSE
T-cell antigen CD7
Search

CD7

0.92	T-cell antigen CD7

0.62	GO:0048873	homeostasis of number of cells within a tissue
0.45	GO:0002250	adaptive immune response

0.43	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part

sp|P50284|TNR3_MOUSE
Tumor necrosis factor receptor superfamily member 3
Search

LTBR

0.97	Lymphotoxin beta receptor

0.83	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.79	GO:0048534	hematopoietic or lymphoid organ development
0.74	GO:0006955	immune response
0.66	GO:0001773	myeloid dendritic cell activation
0.65	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway
0.65	GO:0071260	cellular response to mechanical stimulus
0.63	GO:0046330	positive regulation of JNK cascade
0.55	GO:0030154	cell differentiation
0.54	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.53	GO:0032496	response to lipopolysaccharide

0.60	GO:0031625	ubiquitin protein ligase binding
0.57	GO:0042802	identical protein binding
0.56	GO:0005031	tumor necrosis factor-activated receptor activity

0.56	GO:0005794	Golgi apparatus
0.46	GO:0005887	integral component of plasma membrane

sp|P50285|FMO1_MOUSE
Dimethylaniline monooxygenase [N-oxide-forming] 1
Search

FMO1

0.60	Flavin-containing monooxygenase

0.63	GO:0070995	NADPH oxidation
0.51	GO:0009404	toxin metabolic process
0.45	GO:0017144	drug metabolic process
0.43	GO:0006082	organic acid metabolic process
0.41	GO:0006805	xenobiotic metabolic process
0.39	GO:0032496	response to lipopolysaccharide
0.39	GO:0006970	response to osmotic stress
0.34	GO:0044248	cellular catabolic process

0.78	GO:0004499	N,N-dimethylaniline monooxygenase activity
0.70	GO:0050661	NADP binding
0.66	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0005515	protein binding

0.41	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0031090	organelle membrane
0.35	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.78

EC:1.14.13.8

GO:0004499

sp|P50289|ASPX_MOUSE
Acrosomal protein SP-10
Search

ACRV1

0.94	Acrosomal vesicle protein 1

0.37

GO:0007275

multicellular organism development

0.84

GO:0001669

acrosomal vesicle

sp|P50294|ARY1_MOUSE
Arylamine N-acetyltransferase 1
Search

NAT1

0.86	N-acetyltransferase 1

0.30

GO:0008152

metabolic process

0.67

GO:0016407

acetyltransferase activity

0.67

GO:0016407

sp|P50295|ARY2_MOUSE
Arylamine N-acetyltransferase 2
Search

NAT1

0.62	Arylamine N-acetyltransferase

0.39	GO:0097068	response to thyroxine
0.37	GO:0001889	liver development
0.37	GO:0007568	aging
0.37	GO:0009410	response to xenobiotic stimulus
0.36	GO:1902475	L-alpha-amino acid transmembrane transport
0.35	GO:0048565	digestive tract development
0.35	GO:0032496	response to lipopolysaccharide
0.35	GO:0001666	response to hypoxia
0.34	GO:0070887	cellular response to chemical stimulus
0.30	GO:0044237	cellular metabolic process

0.67	GO:0016407	acetyltransferase activity
0.46	GO:0016410	N-acyltransferase activity
0.36	GO:0015179	L-amino acid transmembrane transporter activity
0.33	GO:0005515	protein binding

0.37	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.67

GO:0016407

sp|P50296|ARY3_MOUSE
Arylamine N-acetyltransferase 3
Search

NAT1

0.62	Arylamine N-acetyltransferase

0.39	GO:0097068	response to thyroxine
0.38	GO:1902475	L-alpha-amino acid transmembrane transport
0.37	GO:0001889	liver development
0.37	GO:0007568	aging
0.36	GO:0009410	response to xenobiotic stimulus
0.34	GO:0048565	digestive tract development
0.34	GO:0032496	response to lipopolysaccharide
0.34	GO:0001666	response to hypoxia
0.34	GO:0070887	cellular response to chemical stimulus
0.30	GO:0044237	cellular metabolic process

0.67	GO:0016407	acetyltransferase activity
0.46	GO:0016410	N-acyltransferase activity
0.38	GO:0015179	L-amino acid transmembrane transporter activity
0.33	GO:0005515	protein binding

0.37	GO:0005829	cytosol
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.67

GO:0016407

sp|P50396|GDIA_MOUSE
Rab GDP dissociation inhibitor alpha
Search

GDI1

0.68	Rab GDP dissociation inhibitor alpha

0.77	GO:0007264	small GTPase mediated signal transduction
0.76	GO:0043547	positive regulation of GTPase activity
0.65	GO:0015031	protein transport
0.55	GO:0090315	negative regulation of protein targeting to membrane
0.43	GO:0050771	negative regulation of axonogenesis
0.39	GO:0045773	positive regulation of axon extension
0.39	GO:0051592	response to calcium ion
0.35	GO:0051056	regulation of small GTPase mediated signal transduction
0.35	GO:0043312	neutrophil degranulation

0.85	GO:0005093	Rab GDP-dissociation inhibitor activity
0.76	GO:0005096	GTPase activator activity
0.39	GO:0031267	small GTPase binding
0.33	GO:0003723	RNA binding
0.32	GO:0016740	transferase activity

0.53	GO:0043209	myelin sheath
0.50	GO:0030496	midbody
0.49	GO:0005737	cytoplasm
0.42	GO:0012505	endomembrane system
0.38	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0043025	neuronal cell body
0.38	GO:0030424	axon
0.35	GO:0043234	protein complex
0.35	GO:0031983	vesicle lumen
0.34	GO:0005925	focal adhesion

0.32

GO:0016740

sp|P50404|SFTPD_MOUSE
Pulmonary surfactant-associated protein D
Search

SFTPD

0.96	Pulmonary surfactant-associated protein D

0.63	GO:1905226	regulation of adhesion of symbiont to host epithelial cell
0.62	GO:0043129	surfactant homeostasis
0.61	GO:0043152	induction of bacterial agglutination
0.61	GO:0052405	negative regulation by host of symbiont molecular function
0.60	GO:0048286	lung alveolus development
0.46	GO:0007585	respiratory gaseous exchange
0.44	GO:0045087	innate immune response
0.41	GO:0032703	negative regulation of interleukin-2 production
0.40	GO:0050766	positive regulation of phagocytosis
0.40	GO:0042130	negative regulation of T cell proliferation

0.52	GO:0005201	extracellular matrix structural constituent
0.44	GO:0042802	identical protein binding
0.43	GO:0030246	carbohydrate binding
0.37	GO:0001530	lipopolysaccharide binding
0.35	GO:0036094	small molecule binding
0.34	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0005178	integrin binding
0.34	GO:0048407	platelet-derived growth factor binding
0.33	GO:0005044	scavenger receptor activity
0.33	GO:0030169	low-density lipoprotein particle binding

0.76	GO:0005581	collagen trimer
0.53	GO:0005578	proteinaceous extracellular matrix
0.51	GO:0044420	extracellular matrix component
0.43	GO:0005615	extracellular space
0.38	GO:0031410	cytoplasmic vesicle
0.37	GO:0005783	endoplasmic reticulum
0.37	GO:0099081	supramolecular polymer
0.36	GO:0005764	lysosome
0.36	GO:0019867	outer membrane
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

0.32

GO:0004713

sp|P50405|PSPB_MOUSE
Pulmonary surfactant-associated protein B
Search

SFTPB

0.96	Pulmonary surfactant-associated protein B

0.71	GO:0006665	sphingolipid metabolic process
0.59	GO:0007585	respiratory gaseous exchange
0.52	GO:0009887	animal organ morphogenesis
0.50	GO:0043085	positive regulation of catalytic activity
0.44	GO:0050828	regulation of liquid surface tension
0.44	GO:0033189	response to vitamin A
0.43	GO:0071732	cellular response to nitric oxide
0.43	GO:0055093	response to hyperoxia
0.43	GO:0070741	response to interleukin-6
0.43	GO:0070849	response to epidermal growth factor

0.53	GO:0001664	G-protein coupled receptor binding
0.51	GO:0008047	enzyme activator activity

0.71	GO:0005764	lysosome
0.59	GO:0097208	alveolar lamellar body
0.56	GO:0005771	multivesicular body
0.52	GO:0005615	extracellular space
0.43	GO:0031906	late endosome lumen
0.41	GO:0045334	clathrin-coated endocytic vesicle
0.38	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0005654	nucleoplasm

sp|P50427|STS_MOUSE
Steryl-sulfatase
Search

STS

0.91	Steroid sulfatase

0.39	GO:0007565	female pregnancy
0.38	GO:0008202	steroid metabolic process
0.36	GO:0006687	glycosphingolipid metabolic process
0.36	GO:0043687	post-translational protein modification
0.35	GO:0043627	response to estrogen
0.35	GO:0009268	response to pH
0.35	GO:0043588	skin development
0.35	GO:0007611	learning or memory
0.35	GO:0043434	response to peptide hormone
0.35	GO:0008284	positive regulation of cell proliferation

0.75	GO:0008484	sulfuric ester hydrolase activity
0.34	GO:0046872	metal ion binding
0.34	GO:0004725	protein tyrosine phosphatase activity

0.39	GO:0012505	endomembrane system
0.36	GO:0043227	membrane-bounded organelle
0.36	GO:0044444	cytoplasmic part
0.35	GO:0043229	intracellular organelle
0.35	GO:0043230	extracellular organelle
0.35	GO:0044422	organelle part
0.34	GO:0005615	extracellular space
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0031975	envelope
0.32	GO:0005886	plasma membrane

0.75

GO:0008484

sp|P50428|ARSA_MOUSE
Arylsulfatase A
Search

ARSA

0.57	Arylsulfatase A

0.56	GO:0007339	binding of sperm to zona pellucida
0.42	GO:0051597	response to methylmercury
0.41	GO:0043627	response to estrogen
0.41	GO:0045471	response to ethanol
0.41	GO:0009268	response to pH
0.40	GO:0007584	response to nutrient
0.40	GO:0007417	central nervous system development
0.39	GO:0006914	autophagy
0.36	GO:0043312	neutrophil degranulation
0.35	GO:0006687	glycosphingolipid metabolic process

0.74	GO:0008484	sulfuric ester hydrolase activity
0.39	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding

0.50	GO:0005615	extracellular space
0.42	GO:0031232	extrinsic component of external side of plasma membrane
0.42	GO:0005764	lysosome
0.41	GO:0030141	secretory granule
0.41	GO:0097223	sperm part
0.39	GO:0005768	endosome
0.39	GO:1903561	extracellular vesicle
0.36	GO:0060205	cytoplasmic vesicle lumen
0.36	GO:0005775	vacuolar lumen
0.35	GO:0005788	endoplasmic reticulum lumen

0.74

GO:0008484

sp|P50429|ARSB_MOUSE
Arylsulfatase B
Search

ARSB

0.90	Arylsulfatase B

0.59	GO:0061580	colon epithelial cell migration
0.53	GO:0010632	regulation of epithelial cell migration
0.42	GO:0010976	positive regulation of neuron projection development
0.41	GO:0051597	response to methylmercury
0.40	GO:0043627	response to estrogen
0.40	GO:0009268	response to pH
0.40	GO:0007584	response to nutrient
0.39	GO:0007417	central nervous system development
0.39	GO:0006914	autophagy
0.36	GO:0006687	glycosphingolipid metabolic process

0.74	GO:0008484	sulfuric ester hydrolase activity
0.36	GO:0046872	metal ion binding
0.33	GO:0016491	oxidoreductase activity
0.32	GO:0005515	protein binding

0.41	GO:0005764	lysosome
0.40	GO:0009986	cell surface
0.40	GO:0005791	rough endoplasmic reticulum
0.38	GO:0005794	Golgi apparatus
0.37	GO:0070062	extracellular exosome
0.36	GO:0005788	endoplasmic reticulum lumen
0.36	GO:0005739	mitochondrion
0.36	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.35	GO:0005775	vacuolar lumen

0.74

GO:0008484

sp|P50431|GLYC_MOUSE
Serine hydroxymethyltransferase, cytosolic
Search

SHMT1

0.51	Serine hydroxymethyltransferase, cytosolic

0.74	GO:0051289	protein homotetramerization
0.72	GO:0019264	glycine biosynthetic process from serine
0.70	GO:0035999	tetrahydrofolate interconversion
0.68	GO:1904481	response to tetrahydrofolate
0.67	GO:0006565	L-serine catabolic process
0.62	GO:1990830	cellular response to leukemia inhibitory factor
0.59	GO:0071229	cellular response to acid chemical
0.59	GO:0071417	cellular response to organonitrogen compound
0.58	GO:0006231	dTMP biosynthetic process
0.58	GO:0046655	folic acid metabolic process

0.73	GO:0004372	glycine hydroxymethyltransferase activity
0.67	GO:0070905	serine binding
0.65	GO:0000900	translation repressor activity, nucleic acid binding
0.64	GO:0030170	pyridoxal phosphate binding
0.60	GO:0048027	mRNA 5'-UTR binding
0.56	GO:0042803	protein homodimerization activity
0.50	GO:0008732	L-allo-threonine aldolase activity
0.50	GO:0008168	methyltransferase activity

0.61	GO:0005829	cytosol
0.49	GO:0005634	nucleus
0.48	GO:0005739	mitochondrion
0.47	GO:0070062	extracellular exosome

0.73

EC:2.1.2.1

GO:0004372

sp|P50446|K2C6A_MOUSE
Keratin, type II cytoskeletal 6A
Search

KRT5

0.86	Keratin, type II cytoskeletal 5

0.45	GO:0002244	hematopoietic progenitor cell differentiation
0.42	GO:0031424	keratinization
0.39	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.38	GO:0045104	intermediate filament cytoskeleton organization
0.38	GO:0002009	morphogenesis of an epithelium
0.38	GO:0051803	negative regulation of cytolysis in other organism involved in symbiotic interaction
0.38	GO:0001898	regulation of cytolysis by symbiont of host cells
0.38	GO:0050830	defense response to Gram-positive bacterium
0.38	GO:2000536	negative regulation of entry of bacterium into host cell
0.38	GO:0012501	programmed cell death

0.62	GO:0005198	structural molecule activity
0.49	GO:0097110	scaffold protein binding

0.83	GO:0045095	keratin filament
0.40	GO:0005739	mitochondrion
0.40	GO:0070062	extracellular exosome
0.39	GO:0005886	plasma membrane
0.36	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.33	GO:0036338	viral membrane

sp|P50462|CSRP3_MOUSE
Cysteine and glycine-rich protein 3
Search

CSRP3

0.91	Cysteine and glycine rich protein 3

0.55	GO:0060047	heart contraction
0.54	GO:0030239	myofibril assembly
0.52	GO:0035995	detection of muscle stretch
0.50	GO:0003300	cardiac muscle hypertrophy
0.49	GO:0006941	striated muscle contraction
0.48	GO:0002026	regulation of the force of heart contraction
0.48	GO:0055013	cardiac muscle cell development
0.46	GO:0006874	cellular calcium ion homeostasis
0.46	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0033365	protein localization to organelle

0.53	GO:0046872	metal ion binding
0.51	GO:0031433	telethonin binding
0.50	GO:0008307	structural constituent of muscle
0.47	GO:0042805	actinin binding
0.45	GO:0042802	identical protein binding
0.30	GO:0008134	transcription factor binding
0.30	GO:0003779	actin binding

0.49	GO:0030018	Z disc
0.36	GO:0005634	nucleus
0.30	GO:0005856	cytoskeleton

sp|P50481|LHX3_MOUSE
LIM/homeobox protein Lhx3
Search

LHX3

0.95	Lim homeobox protein 3 splice variant

0.69	GO:0021526	medial motor column neuron differentiation
0.68	GO:0021521	ventral spinal cord interneuron specification
0.64	GO:0008045	motor neuron axon guidance
0.63	GO:0021527	spinal cord association neuron differentiation
0.63	GO:0021520	spinal cord motor neuron cell fate specification
0.61	GO:0021983	pituitary gland development
0.60	GO:0001890	placenta development
0.59	GO:0048839	inner ear development
0.59	GO:0043066	negative regulation of apoptotic process
0.58	GO:0045944	positive regulation of transcription by RNA polymerase II

0.63	GO:0043565	sequence-specific DNA binding
0.60	GO:0001085	RNA polymerase II transcription factor binding
0.58	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.57	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.56	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0046872	metal ion binding
0.53	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.55	GO:0005667	transcription factor complex

sp|P50516|VATA_MOUSE
V-type proton ATPase catalytic subunit A
Search

ATP6V1A

0.92	ATPase H+-transporting V1 subunit A

0.75	GO:0015991	ATP hydrolysis coupled proton transport
0.64	GO:0036295	cellular response to increased oxygen levels
0.62	GO:0046034	ATP metabolic process
0.57	GO:0006875	cellular metal ion homeostasis
0.56	GO:0055072	iron ion homeostasis
0.40	GO:0055078	sodium ion homeostasis
0.39	GO:0030004	cellular monovalent inorganic cation homeostasis
0.39	GO:0055074	calcium ion homeostasis
0.39	GO:0072503	cellular divalent inorganic cation homeostasis

0.80	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.68	GO:0016324	apical plasma membrane
0.61	GO:0005902	microvillus
0.60	GO:0043209	myelin sheath
0.52	GO:0005829	cytosol
0.49	GO:0005765	lysosomal membrane
0.47	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|P50518|VATE1_MOUSE
V-type proton ATPase subunit E 1
Search

ATP6V1E1

0.96	Vacuolar proton-ATPase E-subunit

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.45	GO:0060036	notochord cell vacuolation
0.45	GO:0033336	caudal fin development
0.44	GO:0031101	fin regeneration
0.42	GO:0060041	retina development in camera-type eye
0.35	GO:0090383	phagosome acidification
0.35	GO:0033572	transferrin transport
0.35	GO:0008286	insulin receptor signaling pathway
0.35	GO:0016241	regulation of macroautophagy

0.81	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.52	GO:0008553	proton-exporting ATPase activity, phosphorylative mechanism
0.48	GO:0051117	ATPase binding
0.44	GO:0008900	potassium:proton exchanging ATPase activity

0.72	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain
0.48	GO:0031410	cytoplasmic vesicle
0.47	GO:0005902	microvillus
0.47	GO:0016324	apical plasma membrane
0.46	GO:0012505	endomembrane system
0.44	GO:0097223	sperm part
0.43	GO:0005829	cytosol
0.40	GO:0005739	mitochondrion
0.37	GO:0005765	lysosomal membrane
0.36	GO:0070062	extracellular exosome

0.52

EC:3.6.3.6

GO:0008553

sp|P50538|MAD1_MOUSE
Max dimerization protein 1
Search

MXD1

0.97	Max dimerization protein 1

0.55	GO:0000122	negative regulation of transcription by RNA polymerase II
0.35	GO:0016070	RNA metabolic process
0.35	GO:0010467	gene expression
0.35	GO:0008283	cell proliferation
0.35	GO:0034654	nucleobase-containing compound biosynthetic process
0.34	GO:0009059	macromolecule biosynthetic process
0.34	GO:0007275	multicellular organism development
0.34	GO:0044260	cellular macromolecule metabolic process

0.66	GO:0046983	protein dimerization activity
0.56	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.54	GO:0000987	proximal promoter sequence-specific DNA binding
0.35	GO:0003714	transcription corepressor activity

0.52	GO:0000790	nuclear chromatin
0.50	GO:0005829	cytosol
0.49	GO:0005654	nucleoplasm
0.45	GO:0005739	mitochondrion
0.40	GO:0090575	RNA polymerase II transcription factor complex
0.39	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

sp|P50540|MXI1_MOUSE
Max-interacting protein 1
Search

MXI1

0.95	Max-interacting protein 1

0.41	GO:0000122	negative regulation of transcription by RNA polymerase II
0.38	GO:0042994	cytoplasmic sequestering of transcription factor
0.37	GO:0006351	transcription, DNA-templated
0.36	GO:0008285	negative regulation of cell proliferation

0.68	GO:0046983	protein dimerization activity
0.41	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.37	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.37	GO:0003714	transcription corepressor activity

0.40	GO:0005730	nucleolus
0.40	GO:0090575	RNA polymerase II transcription factor complex
0.39	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P50543|S10AB_MOUSE
Protein S100-A11
Search

S100A11

0.80	S100 calcium binding protein A11

0.75	GO:0042127	regulation of cell proliferation
0.48	GO:0098609	cell-cell adhesion
0.37	GO:0007283	spermatogenesis
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0008156	negative regulation of DNA replication
0.34	GO:0051013	microtubule severing
0.33	GO:0051301	cell division
0.33	GO:0007049	cell cycle
0.33	GO:0007165	signal transduction

0.85	GO:0048306	calcium-dependent protein binding
0.70	GO:0005509	calcium ion binding
0.53	GO:0098641	cadherin binding involved in cell-cell adhesion
0.52	GO:0044548	S100 protein binding
0.48	GO:0042803	protein homodimerization activity
0.37	GO:0008270	zinc ion binding
0.35	GO:0008568	microtubule-severing ATPase activity
0.34	GO:0008017	microtubule binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.51	GO:0005913	cell-cell adherens junction
0.51	GO:0001726	ruffle
0.44	GO:0005576	extracellular region
0.42	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.36	GO:0031982	vesicle
0.34	GO:0030496	midbody
0.34	GO:0000922	spindle pole
0.34	GO:0005813	centrosome
0.34	GO:0005874	microtubule

0.35

EC:3.6.4.3

GO:0008568

sp|P50544|ACADV_MOUSE
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial
Search

ACADVL

0.95	Very long-chain specific acyl-CoA dehydrogenaseserine-threonine

0.57	GO:0046322	negative regulation of fatty acid oxidation
0.56	GO:0090181	regulation of cholesterol metabolic process
0.55	GO:0001659	temperature homeostasis
0.54	GO:0045717	negative regulation of fatty acid biosynthetic process
0.54	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase
0.52	GO:0030855	epithelial cell differentiation
0.52	GO:0009409	response to cold
0.43	GO:0060322	head development
0.36	GO:0042760	very long-chain fatty acid catabolic process
0.36	GO:0036498	IRE1-mediated unfolded protein response

0.74	GO:0003995	acyl-CoA dehydrogenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.35	GO:0000062	fatty-acyl-CoA binding

0.54	GO:0042645	mitochondrial nucleoid
0.49	GO:0005730	nucleolus
0.47	GO:0005829	cytosol
0.45	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane

0.74

EC:1.3.99.3

GO:0003995

sp|P50571|GBRB1_MOUSE
Gamma-aminobutyric acid receptor subunit beta-1
Search

GABRB1

0.86	Gamma-aminobutyric acid A receptor

0.60	GO:0007165	signal transduction
0.59	GO:0034220	ion transmembrane transport
0.51	GO:0006821	chloride transport
0.50	GO:0060384	innervation
0.49	GO:0090102	cochlea development
0.49	GO:0060119	inner ear receptor cell development
0.48	GO:0043524	negative regulation of neuron apoptotic process
0.47	GO:0007605	sensory perception of sound
0.46	GO:0071420	cellular response to histamine
0.42	GO:0032570	response to progesterone

0.82	GO:0004890	GABA-A receptor activity
0.74	GO:0005230	extracellular ligand-gated ion channel activity
0.55	GO:0099095	ligand-gated anion channel activity
0.52	GO:0005254	chloride channel activity
0.51	GO:0022835	transmitter-gated channel activity
0.42	GO:0050811	GABA receptor binding
0.34	GO:0042802	identical protein binding
0.32	GO:0003676	nucleic acid binding

0.59	GO:1902711	GABA-A receptor complex
0.55	GO:0005886	plasma membrane
0.42	GO:0034707	chloride channel complex
0.41	GO:0098794	postsynapse
0.40	GO:0030054	cell junction
0.40	GO:0030425	dendrite
0.39	GO:0005635	nuclear envelope
0.36	GO:0031410	cytoplasmic vesicle
0.36	GO:0012506	vesicle membrane
0.35	GO:0060077	inhibitory synapse

sp|P50580|PA2G4_MOUSE
Proliferation-associated protein 2G4
Search

PA2G4

0.69	Proliferation-associated protein 2G4

0.39	GO:0043066	negative regulation of apoptotic process
0.38	GO:0051094	positive regulation of developmental process
0.38	GO:0045595	regulation of cell differentiation
0.37	GO:0045892	negative regulation of transcription, DNA-templated
0.37	GO:0048522	positive regulation of cellular process
0.36	GO:0006417	regulation of translation
0.36	GO:0006364	rRNA processing
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0007050	cell cycle arrest
0.34	GO:0008283	cell proliferation

0.39	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0003700	DNA binding transcription factor activity
0.35	GO:0003723	RNA binding
0.34	GO:0003677	DNA binding
0.34	GO:0046872	metal ion binding
0.34	GO:0038132	neuregulin binding
0.34	GO:0003735	structural constituent of ribosome
0.34	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.33	GO:0030296	protein tyrosine kinase activator activity
0.33	GO:0046982	protein heterodimerization activity

0.47	GO:0005737	cytoplasm
0.38	GO:0005730	nucleolus
0.36	GO:0070062	extracellular exosome
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0031983	vesicle lumen
0.34	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system
0.33	GO:0016328	lateral plasma membrane
0.33	GO:0016323	basolateral plasma membrane
0.33	GO:0016324	apical plasma membrane

0.34

EC:2.7.10.1

GO:0004714

sp|P50586|TUB_MOUSE
Tubby protein
Search

TUB

0.89	Tubby bipartite transcription factor

0.87	GO:0097500	receptor localization to non-motile cilium
0.87	GO:1903546	protein localization to photoreceptor outer segment
0.85	GO:0050766	positive regulation of phagocytosis
0.84	GO:0006910	phagocytosis, recognition
0.84	GO:0045494	photoreceptor cell maintenance
0.81	GO:0060041	retina development in camera-type eye
0.79	GO:0007605	sensory perception of sound
0.59	GO:0009725	response to hormone

0.74	GO:0032403	protein complex binding
0.67	GO:0035091	phosphatidylinositol binding

0.67	GO:0005929	cilium
0.67	GO:0005829	cytosol
0.65	GO:0005576	extracellular region
0.50	GO:0005634	nucleus
0.47	GO:0005886	plasma membrane

sp|P50592|TNF10_MOUSE
Tumor necrosis factor ligand superfamily member 10
Search

TNFSF10

0.96	Tumor necrosis factor ligand superfamily member 10

0.72	GO:0006955	immune response
0.72	GO:0010469	regulation of receptor activity
0.61	GO:0090200	positive regulation of release of cytochrome c from mitochondria
0.60	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway
0.59	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.58	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.42	GO:0008584	male gonad development
0.42	GO:0032868	response to insulin
0.38	GO:0006915	apoptotic process
0.36	GO:2001267	regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

0.81	GO:0005164	tumor necrosis factor receptor binding
0.76	GO:0005125	cytokine activity
0.53	GO:0042802	identical protein binding
0.52	GO:0046872	metal ion binding

0.70	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.34	GO:0005887	integral component of plasma membrane

sp|P50608|FMOD_MOUSE
Fibromodulin
Search

FMOD

0.97	Fibromodulin

0.65	GO:0030199	collagen fibril organization
0.48	GO:0007409	axonogenesis
0.47	GO:0007601	visual perception
0.41	GO:0032914	positive regulation of transforming growth factor beta1 production
0.40	GO:0048513	animal organ development
0.38	GO:0048598	embryonic morphogenesis
0.38	GO:0045944	positive regulation of transcription by RNA polymerase II
0.37	GO:0042340	keratan sulfate catabolic process
0.36	GO:0070848	response to growth factor
0.36	GO:0018146	keratan sulfate biosynthetic process

0.42	GO:0005518	collagen binding
0.32	GO:0004930	G-protein coupled receptor activity

0.75	GO:0005578	proteinaceous extracellular matrix
0.56	GO:0005615	extracellular space
0.39	GO:0044420	extracellular matrix component
0.38	GO:0005581	collagen trimer
0.37	GO:0099512	supramolecular fiber
0.36	GO:0043202	lysosomal lumen
0.36	GO:0005796	Golgi lumen
0.33	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|P50615|BTG3_MOUSE
Protein BTG3
Search

BTG3

0.93	BTG anti-proliferation factor 3

0.68	GO:0008285	negative regulation of cell proliferation
0.65	GO:0045930	negative regulation of mitotic cell cycle
0.36	GO:0006979	response to oxidative stress
0.35	GO:0007050	cell cycle arrest
0.35	GO:0030182	neuron differentiation
0.33	GO:0071805	potassium ion transmembrane transport

0.38	GO:0005515	protein binding
0.34	GO:0016286	small conductance calcium-activated potassium channel activity

0.42	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|P50636|RN19A_MOUSE
E3 ubiquitin-protein ligase RNF19A
Search

RNF19A

0.58	RING-type E3 ubiquitin transferase

0.72	GO:0016567	protein ubiquitination
0.48	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.44	GO:0006511	ubiquitin-dependent protein catabolic process
0.34	GO:0000226	microtubule cytoskeleton organization
0.34	GO:0072643	interferon-gamma secretion
0.34	GO:0042267	natural killer cell mediated cytotoxicity
0.34	GO:0002250	adaptive immune response
0.32	GO:0006468	protein phosphorylation

0.73	GO:0004842	ubiquitin-protein transferase activity
0.53	GO:0016874	ligase activity
0.53	GO:0046872	metal ion binding
0.49	GO:0031624	ubiquitin conjugating enzyme binding
0.45	GO:0061659	ubiquitin-like protein ligase activity
0.34	GO:0008134	transcription factor binding
0.32	GO:0003723	RNA binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.45	GO:0005813	centrosome
0.45	GO:0000151	ubiquitin ligase complex
0.36	GO:0005737	cytoplasm
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.53	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

sp|P50637|TSPO_MOUSE
Translocator protein
Search

TSPO

0.93	Translocator protein isoform PBR (Fragment)

0.62	GO:0072656	maintenance of protein location in mitochondrion
0.61	GO:1903147	negative regulation of autophagy of mitochondrion
0.60	GO:1903579	negative regulation of ATP metabolic process
0.58	GO:0031397	negative regulation of protein ubiquitination
0.58	GO:2000379	positive regulation of reactive oxygen species metabolic process
0.55	GO:0072655	establishment of protein localization to mitochondrion
0.44	GO:0060319	primitive erythrocyte differentiation
0.41	GO:0010266	response to vitamin B1
0.41	GO:0014012	peripheral nervous system axon regeneration
0.41	GO:0051901	positive regulation of mitochondrial depolarization

0.58	GO:0044325	ion channel binding
0.42	GO:0008503	benzodiazepine receptor activity
0.41	GO:0005497	androgen binding
0.38	GO:0015485	cholesterol binding
0.36	GO:0017127	cholesterol transporter activity

0.46	GO:0005739	mitochondrion
0.38	GO:0031968	organelle outer membrane
0.37	GO:0070062	extracellular exosome
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

sp|P50652|FANCC_MOUSE
Fanconi anemia group C protein homolog
Search

FANCC

0.96	Fanconi anemia complementation group C

0.65	GO:0006281	DNA repair
0.51	GO:0097150	neuronal stem cell population maintenance
0.50	GO:0048854	brain morphogenesis
0.49	GO:0002262	myeloid cell homeostasis
0.48	GO:0007281	germ cell development
0.47	GO:0034599	cellular response to oxidative stress
0.46	GO:0000303	response to superoxide
0.46	GO:0006801	superoxide metabolic process
0.46	GO:1901701	cellular response to oxygen-containing compound
0.44	GO:0098869	cellular oxidant detoxification

0.33

GO:0005515

protein binding

0.72	GO:0043240	Fanconi anaemia nuclear complex
0.45	GO:0005829	cytosol

sp|P50704|DEFA6_MOUSE
Alpha-defensin 6/12
Search

0.97	Cryptdin i

0.72	GO:0006952	defense response
0.69	GO:0009617	response to bacterium
0.46	GO:0071216	cellular response to biotic stimulus
0.45	GO:0033993	response to lipid
0.44	GO:1901700	response to oxygen-containing compound
0.43	GO:0071310	cellular response to organic substance
0.43	GO:0019730	antimicrobial humoral response
0.42	GO:0042493	response to drug
0.37	GO:0051673	membrane disruption in other organism
0.36	GO:0031640	killing of cells of other organism

0.37	GO:0008289	lipid binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity
0.33	GO:0043168	anion binding
0.33	GO:0097367	carbohydrate derivative binding

0.73	GO:0005615	extracellular space
0.36	GO:0030141	secretory granule

sp|P50705|DEFA7_MOUSE
Alpha-defensin 7
Search

0.97	Myeloid alpha defensin 9

0.72	GO:0006952	defense response
0.69	GO:0009617	response to bacterium
0.45	GO:0071216	cellular response to biotic stimulus
0.44	GO:0033993	response to lipid
0.43	GO:1901700	response to oxygen-containing compound
0.42	GO:0071310	cellular response to organic substance
0.42	GO:0019730	antimicrobial humoral response
0.41	GO:0042493	response to drug
0.38	GO:0031640	killing of cells of other organism
0.37	GO:0051673	membrane disruption in other organism

0.36	GO:0008289	lipid binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0046982	protein heterodimerization activity
0.33	GO:0043168	anion binding
0.33	GO:0097367	carbohydrate derivative binding

0.73	GO:0005615	extracellular space
0.35	GO:0030141	secretory granule

sp|P50706|DEFA8_MOUSE
Alpha-defensin 8 (Fragment)
Search

0.97	Myeloid alpha defensin 9

0.72	GO:0006952	defense response
0.70	GO:0009617	response to bacterium
0.45	GO:0071216	cellular response to biotic stimulus
0.44	GO:0033993	response to lipid
0.43	GO:1901700	response to oxygen-containing compound
0.42	GO:0071310	cellular response to organic substance
0.42	GO:0019730	antimicrobial humoral response
0.42	GO:0042493	response to drug
0.38	GO:0031640	killing of cells of other organism
0.37	GO:0051673	membrane disruption in other organism

0.37	GO:0008289	lipid binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0046982	protein heterodimerization activity
0.33	GO:0043168	anion binding
0.33	GO:0097367	carbohydrate derivative binding

0.73	GO:0005615	extracellular space
0.35	GO:0030141	secretory granule

sp|P50707|DEFA9_MOUSE
Alpha-defensin 9
Search

0.97	Cryptdin i

0.72	GO:0006952	defense response
0.69	GO:0009617	response to bacterium
0.45	GO:0071216	cellular response to biotic stimulus
0.44	GO:0033993	response to lipid
0.43	GO:1901700	response to oxygen-containing compound
0.43	GO:0071310	cellular response to organic substance
0.42	GO:0019730	antimicrobial humoral response
0.42	GO:0042493	response to drug
0.37	GO:0051673	membrane disruption in other organism
0.36	GO:0031640	killing of cells of other organism

0.37	GO:0008289	lipid binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity
0.33	GO:0043168	anion binding
0.33	GO:0097367	carbohydrate derivative binding

0.73	GO:0005615	extracellular space
0.36	GO:0030141	secretory granule

sp|P50708|DFA10_MOUSE
Alpha-defensin 10
Search

0.97	Cryptdin i

0.72	GO:0006952	defense response
0.68	GO:0009617	response to bacterium
0.45	GO:0071216	cellular response to biotic stimulus
0.44	GO:0033993	response to lipid
0.43	GO:1901700	response to oxygen-containing compound
0.42	GO:0071310	cellular response to organic substance
0.42	GO:0019730	antimicrobial humoral response
0.41	GO:0042493	response to drug
0.38	GO:0031640	killing of cells of other organism
0.37	GO:0051673	membrane disruption in other organism

0.36	GO:0008289	lipid binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0046982	protein heterodimerization activity
0.33	GO:0043168	anion binding
0.33	GO:0097367	carbohydrate derivative binding

0.73	GO:0005615	extracellular space
0.35	GO:0030141	secretory granule

sp|P50709|DFA11_MOUSE
Alpha-defensin 11 (Fragment)
Search

0.97	Cryptdin i

0.72	GO:0006952	defense response
0.70	GO:0009617	response to bacterium
0.46	GO:0071216	cellular response to biotic stimulus
0.45	GO:0033993	response to lipid
0.44	GO:1901700	response to oxygen-containing compound
0.43	GO:0071310	cellular response to organic substance
0.43	GO:0019730	antimicrobial humoral response
0.42	GO:0042493	response to drug
0.37	GO:0051673	membrane disruption in other organism
0.36	GO:0031640	killing of cells of other organism

0.37	GO:0008289	lipid binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity
0.33	GO:0043168	anion binding
0.33	GO:0097367	carbohydrate derivative binding

0.73	GO:0005615	extracellular space
0.36	GO:0030141	secretory granule

sp|P50711|DFA13_MOUSE
Alpha-defensin 13
Search

0.97	Cryptdin i

0.72	GO:0006952	defense response
0.69	GO:0009617	response to bacterium
0.46	GO:0071216	cellular response to biotic stimulus
0.44	GO:0033993	response to lipid
0.43	GO:1901700	response to oxygen-containing compound
0.43	GO:0071310	cellular response to organic substance
0.42	GO:0019730	antimicrobial humoral response
0.42	GO:0042493	response to drug
0.37	GO:0051673	membrane disruption in other organism
0.36	GO:0031640	killing of cells of other organism

0.37	GO:0008289	lipid binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity
0.33	GO:0043168	anion binding
0.33	GO:0097367	carbohydrate derivative binding

0.73	GO:0005615	extracellular space
0.35	GO:0030141	secretory granule

sp|P50712|DFA14_MOUSE
Alpha-defensin 14 (Fragment)
Search

0.97	Myeloid alpha defensin 9

0.72	GO:0006952	defense response
0.69	GO:0009617	response to bacterium
0.45	GO:0071216	cellular response to biotic stimulus
0.44	GO:0033993	response to lipid
0.43	GO:1901700	response to oxygen-containing compound
0.42	GO:0071310	cellular response to organic substance
0.42	GO:0019730	antimicrobial humoral response
0.42	GO:0042493	response to drug
0.38	GO:0031640	killing of cells of other organism
0.37	GO:0051673	membrane disruption in other organism

0.37	GO:0008289	lipid binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0046982	protein heterodimerization activity
0.33	GO:0043168	anion binding
0.33	GO:0097367	carbohydrate derivative binding

0.73	GO:0005615	extracellular space
0.35	GO:0030141	secretory granule

sp|P50713|DFA15_MOUSE
Alpha-defensin 15
Search

0.97	Myeloid alpha defensin 9

0.72	GO:0006952	defense response
0.68	GO:0009617	response to bacterium
0.44	GO:0071216	cellular response to biotic stimulus
0.43	GO:0033993	response to lipid
0.42	GO:1901700	response to oxygen-containing compound
0.42	GO:0071310	cellular response to organic substance
0.42	GO:0019730	antimicrobial humoral response
0.41	GO:0042493	response to drug
0.38	GO:0031640	killing of cells of other organism
0.37	GO:0051673	membrane disruption in other organism

0.36	GO:0008289	lipid binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0046982	protein heterodimerization activity
0.33	GO:0043168	anion binding
0.33	GO:0097367	carbohydrate derivative binding

0.73	GO:0005615	extracellular space
0.35	GO:0030141	secretory granule

sp|P50714|DFA16_MOUSE
Alpha-defensin 16
Search

0.97	Cryptdin i

0.72	GO:0006952	defense response
0.69	GO:0009617	response to bacterium
0.46	GO:0071216	cellular response to biotic stimulus
0.45	GO:0033993	response to lipid
0.44	GO:1901700	response to oxygen-containing compound
0.43	GO:0071310	cellular response to organic substance
0.43	GO:0019730	antimicrobial humoral response
0.42	GO:0042493	response to drug
0.37	GO:0051673	membrane disruption in other organism
0.36	GO:0031640	killing of cells of other organism

0.37	GO:0008289	lipid binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity
0.33	GO:0043168	anion binding
0.33	GO:0097367	carbohydrate derivative binding

0.73	GO:0005615	extracellular space
0.36	GO:0030141	secretory granule

sp|P50715|DFAR7_MOUSE
Alpha-defensin-related sequence 7
Search

0.97	Cryptdin i

0.72	GO:0006952	defense response
0.63	GO:0009617	response to bacterium
0.44	GO:0033993	response to lipid
0.43	GO:0071216	cellular response to biotic stimulus
0.43	GO:1901700	response to oxygen-containing compound
0.41	GO:0071310	cellular response to organic substance
0.41	GO:0019730	antimicrobial humoral response
0.40	GO:0042493	response to drug
0.39	GO:0051673	membrane disruption in other organism
0.36	GO:0031640	killing of cells of other organism

0.40	GO:0042803	protein homodimerization activity
0.40	GO:0046982	protein heterodimerization activity
0.38	GO:0001530	lipopolysaccharide binding
0.35	GO:0005543	phospholipid binding

0.73	GO:0005615	extracellular space
0.38	GO:0030141	secretory granule
0.30	GO:0016020	membrane

sp|P50716|DAR12_MOUSE
Alpha-defensin-related sequence 12
Search

0.97	Cryptdin i

0.72	GO:0006952	defense response
0.64	GO:0009617	response to bacterium
0.43	GO:0033993	response to lipid
0.43	GO:0071216	cellular response to biotic stimulus
0.42	GO:1901700	response to oxygen-containing compound
0.41	GO:0019730	antimicrobial humoral response
0.40	GO:0071310	cellular response to organic substance
0.40	GO:0042493	response to drug
0.39	GO:0051673	membrane disruption in other organism
0.36	GO:0031640	killing of cells of other organism

0.40	GO:0042803	protein homodimerization activity
0.40	GO:0046982	protein heterodimerization activity
0.38	GO:0008289	lipid binding
0.35	GO:0005520	insulin-like growth factor binding
0.34	GO:0097367	carbohydrate derivative binding
0.33	GO:0043168	anion binding

0.73	GO:0005615	extracellular space
0.38	GO:0030141	secretory granule
0.30	GO:0031224	intrinsic component of membrane

sp|P50752|TNNT2_MOUSE
Troponin T, cardiac muscle
Search

TNNT2

0.92	Cardiac troponin T

0.83	GO:0006937	regulation of muscle contraction
0.62	GO:0030049	muscle filament sliding
0.61	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.59	GO:0008016	regulation of heart contraction
0.58	GO:0051592	response to calcium ion
0.58	GO:0060047	heart contraction
0.58	GO:0006941	striated muscle contraction
0.56	GO:0032780	negative regulation of ATPase activity
0.56	GO:0032781	positive regulation of ATPase activity
0.44	GO:0045214	sarcomere organization

0.62	GO:0030172	troponin C binding
0.62	GO:0031013	troponin I binding
0.58	GO:0005523	tropomyosin binding
0.52	GO:0003779	actin binding
0.38	GO:0030674	protein binding, bridging
0.36	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0016887	ATPase activity
0.32	GO:0046872	metal ion binding

0.84	GO:0005861	troponin complex
0.58	GO:0097512	cardiac myofibril
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.34

GO:0016887

sp|P50992|ATP4B_MOUSE
Potassium-transporting ATPase subunit beta
Search

ATP4B

0.80	Potassium-transporting ATPase subunit beta

0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.40	GO:0032496	response to lipopolysaccharide
0.40	GO:0048923	posterior lateral line neuromast hair cell differentiation
0.40	GO:0007155	cell adhesion
0.40	GO:0048840	otolith development
0.40	GO:0010243	response to organonitrogen compound
0.40	GO:0001964	startle response
0.39	GO:0042472	inner ear morphogenesis
0.39	GO:0033577	protein glycosylation in endoplasmic reticulum

0.42	GO:0008900	potassium:proton exchanging ATPase activity
0.36	GO:0046982	protein heterodimerization activity
0.33	GO:0051117	ATPase binding
0.33	GO:0005391	sodium:potassium-exchanging ATPase activity
0.33	GO:0001671	ATPase activator activity

0.85	GO:0005890	sodium:potassium-exchanging ATPase complex
0.36	GO:0005783	endoplasmic reticulum

0.42

EC:3.6.3.10

GO:0008900

sp|P51125|ICAL_MOUSE
Calpastatin
Search

CAST

0.65	Calpastatin

0.80	GO:2000675	negative regulation of type B pancreatic cell apoptotic process
0.79	GO:0097340	inhibition of cysteine-type endopeptidase activity
0.52	GO:0007343	egg activation
0.52	GO:0031100	animal organ regeneration
0.52	GO:0045445	myoblast differentiation
0.52	GO:0071157	negative regulation of cell cycle arrest
0.51	GO:0007520	myoblast fusion
0.51	GO:0001889	liver development
0.49	GO:0007568	aging
0.49	GO:0007420	brain development

0.85	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity
0.71	GO:0045296	cadherin binding
0.50	GO:0002020	protease binding
0.41	GO:0003723	RNA binding

0.62	GO:0005829	cytosol
0.60	GO:0005783	endoplasmic reticulum
0.42	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P51141|DVL1_MOUSE
Segment polarity protein dishevelled homolog DVL-1
Search

DVL1

0.96	Segment polarity protein dishevelled like protein DVL-1

0.75	GO:0016055	Wnt signaling pathway
0.61	GO:0035556	intracellular signal transduction
0.60	GO:0090178	regulation of establishment of planar polarity involved in neural tube closure
0.60	GO:0014022	neural plate elongation
0.59	GO:0071340	skeletal muscle acetylcholine-gated channel clustering
0.58	GO:0060134	prepulse inhibition
0.58	GO:0048668	collateral sprouting
0.58	GO:0060029	convergent extension involved in organogenesis
0.58	GO:0035372	protein localization to microtubule
0.58	GO:0090103	cochlea morphogenesis

0.59	GO:0005109	frizzled binding
0.56	GO:0008013	beta-catenin binding
0.53	GO:0019901	protein kinase binding
0.50	GO:0042802	identical protein binding
0.43	GO:0048365	Rac GTPase binding
0.38	GO:0002020	protease binding
0.36	GO:0046982	protein heterodimerization activity

0.59	GO:1990909	Wnt signalosome
0.56	GO:0016328	lateral plasma membrane
0.55	GO:0030426	growth cone
0.53	GO:0030424	axon
0.53	GO:0030136	clathrin-coated vesicle
0.53	GO:0098793	presynapse
0.49	GO:0015630	microtubule cytoskeleton
0.44	GO:0005829	cytosol
0.40	GO:0043197	dendritic spine
0.40	GO:0014069	postsynaptic density

sp|P51150|RAB7A_MOUSE
Ras-related protein Rab-7a
Search

RAB7A

0.94	RAB7A, member RAS oncogene family

0.58	GO:0061724	lipophagy
0.57	GO:0007174	epidermal growth factor catabolic process
0.56	GO:0090383	phagosome acidification
0.56	GO:0090385	phagosome-lysosome fusion
0.56	GO:1903542	negative regulation of exosomal secretion
0.55	GO:0022615	protein to membrane docking
0.55	GO:0045022	early endosome to late endosome transport
0.54	GO:1903543	positive regulation of exosomal secretion
0.54	GO:0006622	protein targeting to lysosome
0.53	GO:0008333	endosome to lysosome transport

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.56	GO:1905394	retromer complex binding
0.53	GO:0019003	GDP binding
0.40	GO:0048365	Rac GTPase binding

0.57	GO:0032419	extrinsic component of lysosome membrane
0.55	GO:0005770	late endosome
0.53	GO:0045335	phagocytic vesicle
0.52	GO:0005811	lipid droplet
0.52	GO:0034045	phagophore assembly site membrane
0.51	GO:0010008	endosome membrane
0.51	GO:0030904	retromer complex
0.47	GO:0005794	Golgi apparatus
0.47	GO:0005829	cytosol
0.42	GO:0033162	melanosome membrane

sp|P51162|FABP6_MOUSE
Gastrotropin
Search

FABP6

0.97	Fatty acid binding protein 6

0.39	GO:0006869	lipid transport
0.37	GO:0008202	steroid metabolic process
0.36	GO:0019433	triglyceride catabolic process
0.35	GO:0008285	negative regulation of cell proliferation
0.35	GO:0015850	organic hydroxy compound transport
0.35	GO:0015718	monocarboxylic acid transport
0.35	GO:1901615	organic hydroxy compound metabolic process
0.34	GO:0032787	monocarboxylic acid metabolic process

0.86	GO:0032052	bile acid binding
0.72	GO:0008289	lipid binding

0.49	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P51163|HEM4_MOUSE
Uroporphyrinogen-III synthase
Search

UROS

0.48	Uroporphyrinogen-III synthase

0.69	GO:0033014	tetrapyrrole biosynthetic process
0.63	GO:0046502	uroporphyrinogen III metabolic process
0.52	GO:0042168	heme metabolic process
0.51	GO:0046148	pigment biosynthetic process
0.47	GO:0051188	cofactor biosynthetic process
0.46	GO:0046394	carboxylic acid biosynthetic process
0.44	GO:0070541	response to platinum ion
0.44	GO:0071418	cellular response to amine stimulus
0.43	GO:0071243	cellular response to arsenic-containing substance
0.39	GO:0046677	response to antibiotic

0.79	GO:0004852	uroporphyrinogen-III synthase activity
0.36	GO:0048037	cofactor binding

0.45	GO:0005739	mitochondrion
0.38	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.79	EC:4.2.1.75	GO:0004852
0.79	KEGG:R03165	GO:0004852

sp|P51174|ACADL_MOUSE
Long-chain specific acyl-CoA dehydrogenase, mitochondrial
Search

ACADL

0.96	Acyl-CoA dehydrogenase long chain

0.85	GO:0042758	long-chain fatty acid catabolic process
0.53	GO:0055114	oxidation-reduction process

0.86	GO:0004466	long-chain-acyl-CoA dehydrogenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding

0.30

GO:0031224

intrinsic component of membrane

0.86

EC:1.3.99.13

GO:0004466

sp|P51175|PPOX_MOUSE
Protoporphyrinogen oxidase
Search

PPOX

0.53	Protoporphyrinogen oxidase

0.72	GO:0006782	protoporphyrinogen IX biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.37	GO:0042493	response to drug

0.80	GO:0070818	protoporphyrinogen oxidase activity
0.74	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
0.34	GO:0050660	flavin adenine dinucleotide binding

0.60	GO:0031966	mitochondrial membrane
0.60	GO:0019866	organelle inner membrane
0.54	GO:0031300	intrinsic component of organelle membrane
0.35	GO:0005758	mitochondrial intermembrane space
0.30	GO:0016021	integral component of membrane

0.74

EC:1.3.3

GO:0016634

sp|P51180|MIP_MOUSE
Lens fiber major intrinsic protein
Search

MIP

0.94	Major intrinsic protein of eye lens fiber

0.65	GO:0006833	water transport
0.64	GO:1990349	gap junction-mediated intercellular transport
0.63	GO:0002088	lens development in camera-type eye
0.59	GO:0051289	protein homotetramerization
0.55	GO:0055085	transmembrane transport
0.54	GO:0045785	positive regulation of cell adhesion
0.54	GO:0007601	visual perception
0.41	GO:0006811	ion transport
0.38	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.37	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

0.69	GO:0022803	passive transmembrane transporter activity
0.66	GO:0005372	water transmembrane transporter activity
0.59	GO:0005212	structural constituent of eye lens
0.42	GO:0005516	calmodulin binding
0.36	GO:0015168	glycerol transmembrane transporter activity
0.35	GO:0046983	protein dimerization activity

0.51	GO:0005783	endoplasmic reticulum
0.51	GO:0016324	apical plasma membrane
0.45	GO:0005887	integral component of plasma membrane
0.44	GO:0005921	gap junction
0.38	GO:0009925	basal plasma membrane
0.38	GO:0016328	lateral plasma membrane
0.35	GO:0070062	extracellular exosome
0.35	GO:0009897	external side of plasma membrane
0.34	GO:0055037	recycling endosome
0.33	GO:0042807	central vacuole

sp|P51410|RL9_MOUSE
60S ribosomal protein L9
Search

RPL9

0.72	Ribosomal protein L9, pseudogene 6

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:1990090	cellular response to nerve growth factor stimulus
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis

0.66	GO:0019843	rRNA binding
0.64	GO:0003735	structural constituent of ribosome
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.47	GO:0044445	cytosolic part
0.41	GO:0044446	intracellular organelle part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P51432|PLCB3_MOUSE
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
Search

PLCB3

0.54	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3

0.76	GO:0003073	regulation of systemic arterial blood pressure
0.69	GO:0016042	lipid catabolic process
0.65	GO:0043647	inositol phosphate metabolic process
0.63	GO:0007223	Wnt signaling pathway, calcium modulating pathway
0.63	GO:0035556	intracellular signal transduction
0.61	GO:0007186	G-protein coupled receptor signaling pathway
0.56	GO:0046488	phosphatidylinositol metabolic process
0.55	GO:0006892	post-Golgi vesicle-mediated transport
0.53	GO:2000560	positive regulation of CD24 biosynthetic process
0.53	GO:2000438	negative regulation of monocyte extravasation

0.78	GO:0004435	phosphatidylinositol phospholipase C activity
0.74	GO:0005516	calmodulin binding
0.73	GO:0045296	cadherin binding
0.67	GO:0005509	calcium ion binding
0.61	GO:0004871	signal transducer activity
0.50	GO:0005521	lamin binding
0.49	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.46	GO:0005096	GTPase activator activity
0.46	GO:0042803	protein homodimerization activity
0.44	GO:0019899	enzyme binding

0.60	GO:0005654	nucleoplasm
0.57	GO:0005829	cytosol
0.56	GO:0042383	sarcolemma
0.54	GO:0043234	protein complex
0.48	GO:0043209	myelin sheath
0.47	GO:0031965	nuclear membrane
0.46	GO:0000790	nuclear chromatin
0.43	GO:0070062	extracellular exosome

0.78	EC:3.1.4.11	GO:0004435
0.78	KEGG:R03435	GO:0004435

sp|P51436|DRD4_MOUSE
D(4) dopamine receptor
Search

DRD4

0.88	D(4) dopamine receptor isoform A

0.85	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway
0.57	GO:0032417	positive regulation of sodium:proton antiporter activity
0.56	GO:0034776	response to histamine
0.56	GO:0060080	inhibitory postsynaptic potential
0.56	GO:0042053	regulation of dopamine metabolic process
0.56	GO:0048148	behavioral response to cocaine
0.56	GO:0001975	response to amphetamine
0.55	GO:1901386	negative regulation of voltage-gated calcium channel activity
0.55	GO:0042596	fear response
0.53	GO:0008344	adult locomotory behavior

0.85	GO:0004952	dopamine neurotransmitter receptor activity
0.57	GO:0051380	norepinephrine binding
0.57	GO:0051379	epinephrine binding
0.56	GO:0035240	dopamine binding
0.51	GO:0017124	SH3 domain binding
0.49	GO:0042802	identical protein binding
0.36	GO:0015459	potassium channel regulator activity
0.35	GO:0046872	metal ion binding

0.66	GO:0005887	integral component of plasma membrane
0.51	GO:0098794	postsynapse
0.37	GO:0043195	terminal bouton
0.37	GO:0044309	neuron spine
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.36	GO:0012506	vesicle membrane
0.36	GO:0005938	cell cortex

sp|P51437|CAMP_MOUSE
Cathelicidin antimicrobial peptide
Search

CAMP

0.96	Preprocathelicidin antimicrobial peptide

0.72	GO:0006952	defense response
0.66	GO:0009617	response to bacterium
0.60	GO:0044140	negative regulation of growth of symbiont on or near host surface
0.56	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.56	GO:0044130	negative regulation of growth of symbiont in host
0.55	GO:0051851	modification by host of symbiont morphology or physiology
0.53	GO:0051883	killing of cells in other organism involved in symbiotic interaction
0.46	GO:0071354	cellular response to interleukin-6
0.46	GO:0002385	mucosal immune response
0.45	GO:0071347	cellular response to interleukin-1

0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.56	GO:0042581	specific granule
0.40	GO:0042995	cell projection
0.37	GO:1904724	tertiary granule lumen
0.37	GO:0034774	secretory granule lumen
0.30	GO:0016020	membrane

sp|P51448|RORA_MOUSE
Nuclear receptor ROR-alpha
Search

RORA

0.97	Thyroid hormone nuclear receptor alpha

0.79	GO:0030522	intracellular receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0021924	cell proliferation in external granule layer
0.55	GO:0072539	T-helper 17 cell differentiation
0.55	GO:2000188	regulation of cholesterol homeostasis
0.54	GO:0010575	positive regulation of vascular endothelial growth factor production

0.81	GO:0004879	nuclear receptor activity
0.79	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0008270	zinc ion binding
0.56	GO:0008142	oxysterol binding
0.55	GO:0001222	transcription corepressor binding
0.55	GO:0001223	transcription coactivator binding
0.52	GO:0001047	core promoter binding
0.52	GO:0008013	beta-catenin binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding

0.61	GO:0005634	nucleus
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0043234	protein complex

sp|P51450|RORG_MOUSE
Nuclear receptor ROR-gamma
Search

RORC

0.90	RAR-related orphan nuclear receptor variant 2

0.80	GO:0030522	intracellular receptor signaling pathway
0.79	GO:0043401	steroid hormone mediated signaling pathway
0.64	GO:0036315	cellular response to sterol
0.58	GO:0000122	negative regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.41	GO:0007623	circadian rhythm
0.40	GO:0072615	interleukin-17 secretion
0.39	GO:0045586	regulation of gamma-delta T cell differentiation
0.39	GO:0070244	negative regulation of thymocyte apoptotic process
0.39	GO:0072538	T-helper 17 type immune response

0.82	GO:0004879	nuclear receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.67	GO:0008142	oxysterol binding
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.58	GO:0001012	RNA polymerase II regulatory region DNA binding
0.55	GO:0003690	double-stranded DNA binding
0.39	GO:0001223	transcription coactivator binding

0.61	GO:0005634	nucleus
0.53	GO:0031974	membrane-enclosed lumen
0.47	GO:0044446	intracellular organelle part
0.38	GO:0009897	external side of plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P51491|OPSB_MOUSE
Short-wave-sensitive opsin 1
Search

0.96	Blue-sensitive visual pigment opsin

0.79	GO:0007602	phototransduction
0.78	GO:0007601	visual perception
0.75	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.43	GO:0009584	detection of visible light
0.43	GO:0016038	absorption of visible light
0.34	GO:0001523	retinoid metabolic process

0.79	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.53	GO:0001750	photoreceptor outer segment
0.35	GO:0043195	terminal bouton
0.34	GO:0060170	ciliary membrane
0.34	GO:0044297	cell body
0.33	GO:0005887	integral component of plasma membrane

sp|P51557|STAR_MOUSE
Steroidogenic acute regulatory protein, mitochondrial
Search

STAR

0.94	Steroidogenic acute regulatory protein, mitochondrial

0.82	GO:0030301	cholesterol transport
0.76	GO:0006694	steroid biosynthetic process
0.64	GO:1904253	positive regulation of bile acid metabolic process
0.62	GO:0070857	regulation of bile acid biosynthetic process
0.62	GO:0008211	glucocorticoid metabolic process
0.62	GO:0010893	positive regulation of steroid biosynthetic process
0.52	GO:0031328	positive regulation of cellular biosynthetic process
0.48	GO:0044255	cellular lipid metabolic process
0.47	GO:0008203	cholesterol metabolic process
0.42	GO:0042747	circadian sleep/wake cycle, REM sleep

0.85	GO:0017127	cholesterol transporter activity
0.82	GO:0015485	cholesterol binding
0.35	GO:0005515	protein binding

0.59	GO:0005739	mitochondrion
0.39	GO:0043025	neuronal cell body
0.38	GO:0031970	organelle envelope lumen
0.38	GO:0043005	neuron projection
0.37	GO:0005829	cytosol
0.36	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

sp|P51569|AGAL_MOUSE
Alpha-galactosidase A
Search

GLA

0.94	Alpha-galactosidase A

0.60	GO:0005975	carbohydrate metabolic process
0.51	GO:0016139	glycoside catabolic process
0.50	GO:0046477	glycosylceramide catabolic process
0.40	GO:0051001	negative regulation of nitric-oxide synthase activity
0.40	GO:1904406	negative regulation of nitric oxide metabolic process
0.39	GO:1903427	negative regulation of reactive oxygen species biosynthetic process
0.39	GO:0045428	regulation of nitric oxide biosynthetic process
0.38	GO:0030282	bone mineralization
0.37	GO:0031327	negative regulation of cellular biosynthetic process
0.35	GO:0043312	neutrophil degranulation

0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0005102	receptor binding
0.41	GO:0016936	galactoside binding
0.34	GO:0004713	protein tyrosine kinase activity
0.34	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly
0.34	GO:0001129	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly
0.34	GO:0017025	TBP-class protein binding
0.33	GO:0004402	histone acetyltransferase activity
0.33	GO:0004812	aminoacyl-tRNA ligase activity

0.52	GO:0005764	lysosome
0.48	GO:0005794	Golgi apparatus
0.46	GO:0005576	extracellular region
0.35	GO:0031982	vesicle
0.35	GO:0005775	vacuolar lumen
0.33	GO:0005669	transcription factor TFIID complex
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.66

EC:3.2.1

GO:0004553

sp|P51576|P2RX1_MOUSE
P2X purinoceptor 1
Search

0.20	Purinergic receptor P2X, ligand-gated ion channel, 1 (Fragment)

0.85	GO:0033198	response to ATP
0.85	GO:0035590	purinergic nucleotide receptor signaling pathway
0.80	GO:0060079	excitatory postsynaptic potential
0.61	GO:0098655	cation transmembrane transport

0.85	GO:0004931	extracellularly ATP-gated cation channel activity
0.85	GO:0016502	nucleotide receptor activity
0.84	GO:0035586	purinergic receptor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.78	GO:0098794	postsynapse
0.67	GO:0005887	integral component of plasma membrane

sp|P51612|XPC_MOUSE
DNA repair protein complementing XP-C cells homolog
Search

XPC

0.93	Xeroderma pigmentosum complementation group C

0.73	GO:0006289	nucleotide-excision repair
0.59	GO:0070914	UV-damage excision repair
0.58	GO:0010224	response to UV-B
0.58	GO:0031573	intra-S DNA damage checkpoint
0.55	GO:1901990	regulation of mitotic cell cycle phase transition
0.48	GO:0051276	chromosome organization
0.46	GO:0006298	mismatch repair
0.42	GO:0010996	response to auditory stimulus
0.38	GO:0042493	response to drug
0.35	GO:0065004	protein-DNA complex assembly

0.73	GO:0003684	damaged DNA binding
0.54	GO:0003697	single-stranded DNA binding
0.36	GO:0000405	bubble DNA binding
0.36	GO:0000404	heteroduplex DNA loop binding
0.34	GO:0005515	protein binding

0.64	GO:0071942	XPC complex
0.52	GO:0005730	nucleolus
0.52	GO:0000111	nucleotide-excision repair factor 2 complex
0.46	GO:0005739	mitochondrion
0.43	GO:0005886	plasma membrane
0.38	GO:0070062	extracellular exosome
0.34	GO:0005654	nucleoplasm
0.32	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|P51637|CAV3_MOUSE
Caveolin-3
Search

CAV3

0.85

Caveolin

0.85	GO:0070836	caveola assembly
0.76	GO:0046716	muscle cell cellular homeostasis
0.67	GO:0023051	regulation of signaling
0.65	GO:0031623	receptor internalization
0.64	GO:0051001	negative regulation of nitric-oxide synthase activity
0.63	GO:1903844	regulation of cellular response to transforming growth factor beta stimulus
0.63	GO:0098901	regulation of cardiac muscle cell action potential
0.62	GO:0060306	regulation of membrane repolarization
0.62	GO:0086004	regulation of cardiac muscle cell contraction
0.60	GO:0042632	cholesterol homeostasis

0.78	GO:0044325	ion channel binding
0.75	GO:0032947	protein complex scaffold activity
0.59	GO:0099106	ion channel regulator activity
0.57	GO:0071253	connexin binding
0.55	GO:0043014	alpha-tubulin binding
0.54	GO:0017080	sodium channel regulator activity
0.54	GO:0050998	nitric-oxide synthase binding
0.53	GO:0008022	protein C-terminus binding
0.51	GO:0016248	channel inhibitor activity
0.50	GO:0048365	Rac GTPase binding

0.84	GO:0005901	caveola
0.74	GO:0000139	Golgi membrane
0.57	GO:0042383	sarcolemma
0.53	GO:0016010	dystrophin-associated glycoprotein complex
0.53	GO:0005783	endoplasmic reticulum
0.50	GO:0002080	acrosomal membrane
0.50	GO:0005768	endosome
0.49	GO:0005925	focal adhesion
0.48	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0005929	cilium

sp|P51642|CNTF_MOUSE
Ciliary neurotrophic factor
Search

CNTF

0.97	Ciliary neurotrophic factor

0.78	GO:0040007	growth
0.75	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway
0.72	GO:0046533	negative regulation of photoreceptor cell differentiation
0.72	GO:0046668	regulation of retinal cell programmed cell death
0.71	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.69	GO:0043524	negative regulation of neuron apoptotic process
0.69	GO:0048644	muscle organ morphogenesis
0.65	GO:0008284	positive regulation of cell proliferation
0.64	GO:0010469	regulation of receptor activity
0.63	GO:0048666	neuron development

0.72	GO:0005138	interleukin-6 receptor binding
0.66	GO:0008083	growth factor activity
0.57	GO:0005127	ciliary neurotrophic factor receptor binding
0.52	GO:0005125	cytokine activity
0.37	GO:0019888	protein phosphatase regulator activity
0.33	GO:0003676	nucleic acid binding

0.75	GO:0097058	CRLF-CLCF1 complex
0.52	GO:0030424	axon
0.49	GO:0005737	cytoplasm
0.38	GO:0043025	neuronal cell body
0.37	GO:0120038	plasma membrane bounded cell projection part
0.37	GO:0000159	protein phosphatase type 2A complex
0.35	GO:0005634	nucleus

sp|P51655|GPC4_MOUSE
Glypican-4
Search

GPC4

0.90	K-glypican

0.70	GO:0009966	regulation of signal transduction
0.45	GO:0016477	cell migration
0.41	GO:0060028	convergent extension involved in axis elongation
0.41	GO:0036342	post-anal tail morphogenesis
0.41	GO:0060027	convergent extension involved in gastrulation
0.41	GO:0030903	notochord development
0.41	GO:0001702	gastrulation with mouth forming second
0.40	GO:0009826	unidimensional cell growth
0.40	GO:0030166	proteoglycan biosynthetic process
0.40	GO:0051216	cartilage development

0.84	GO:0043395	heparan sulfate proteoglycan binding
0.37	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway

0.83	GO:0046658	anchored component of plasma membrane
0.76	GO:0005578	proteinaceous extracellular matrix
0.53	GO:0009897	external side of plasma membrane
0.50	GO:0005615	extracellular space
0.40	GO:0005796	Golgi lumen
0.37	GO:0043202	lysosomal lumen
0.37	GO:1903561	extracellular vesicle
0.35	GO:0005634	nucleus
0.35	GO:0005887	integral component of plasma membrane

sp|P51656|DHB1_MOUSE
Estradiol 17-beta-dehydrogenase 1
Search

HSD17B1

0.88	17-beta hydroxysteroid dehydrogenase type 1 splice variant

0.80	GO:0006703	estrogen biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.46	GO:0008209	androgen metabolic process
0.44	GO:0061370	testosterone biosynthetic process
0.42	GO:0060348	bone development
0.42	GO:0071248	cellular response to metal ion
0.33	GO:0018106	peptidyl-histidine phosphorylation

0.79	GO:0004303	estradiol 17-beta-dehydrogenase activity
0.46	GO:0047035	testosterone dehydrogenase (NAD+) activity
0.43	GO:1903924	estradiol binding
0.40	GO:0070401	NADP+ binding
0.39	GO:0102131	3-oxo-glutaryl-[acp] methyl ester reductase activity
0.39	GO:0102132	3-oxo-pimeloyl-[acp] methyl ester reductase activity
0.39	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
0.36	GO:0031132	serine 3-dehydrogenase activity
0.35	GO:0030283	testosterone dehydrogenase [NAD(P)] activity
0.33	GO:0004673	protein histidine kinase activity

0.49

GO:0005829

cytosol

0.79	EC:1.1.1.62	GO:0004303
0.46	KEGG:R01836	GO:0047035

sp|P51658|DHB2_MOUSE
Estradiol 17-beta-dehydrogenase 2
Search

HSD17B2

0.88	'D-beta-hydroxybutyrate dehydrogenase, mitochondrial '

0.58	GO:0032526	response to retinoic acid
0.56	GO:0001890	placenta development
0.54	GO:0001701	in utero embryonic development
0.51	GO:0055114	oxidation-reduction process
0.40	GO:0008202	steroid metabolic process
0.39	GO:0042445	hormone metabolic process
0.38	GO:0001501	skeletal system development
0.37	GO:0008610	lipid biosynthetic process
0.36	GO:0035138	pectoral fin morphogenesis
0.36	GO:0042574	retinal metabolic process

0.61	GO:0047035	testosterone dehydrogenase (NAD+) activity
0.60	GO:0004303	estradiol 17-beta-dehydrogenase activity
0.37	GO:0004745	retinol dehydrogenase activity
0.36	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
0.33	GO:0016407	acetyltransferase activity

0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.61	EC:1.1.1.239	GO:0047035
0.61	KEGG:R01836	GO:0047035

sp|P51660|DHB4_MOUSE
Peroxisomal multifunctional enzyme type 2
Search

HSD17B4

0.85	Peroxisomal multifunctional enzyme type 2

0.58	GO:0036111	very long-chain fatty-acyl-CoA metabolic process
0.57	GO:0036112	medium-chain fatty-acyl-CoA metabolic process
0.55	GO:0008209	androgen metabolic process
0.55	GO:0008210	estrogen metabolic process
0.55	GO:0060009	Sertoli cell development
0.52	GO:0000038	very long-chain fatty acid metabolic process
0.52	GO:0055114	oxidation-reduction process
0.50	GO:0009062	fatty acid catabolic process
0.48	GO:0030258	lipid modification
0.43	GO:0048568	embryonic organ development

0.59	GO:0044594	17-beta-hydroxysteroid dehydrogenase (NAD+) activity
0.58	GO:0016508	long-chain-enoyl-CoA hydratase activity
0.50	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
0.49	GO:0042803	protein homodimerization activity
0.48	GO:0005102	receptor binding
0.42	GO:0033989	3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity
0.36	GO:0030283	testosterone dehydrogenase [NAD(P)] activity
0.36	GO:0018812	3-hydroxyacyl-CoA dehydratase activity
0.35	GO:0004303	estradiol 17-beta-dehydrogenase activity
0.35	GO:0016853	isomerase activity

0.51	GO:0005777	peroxisome
0.43	GO:0005739	mitochondrion
0.36	GO:0031903	microbody membrane
0.35	GO:0031907	microbody lumen

0.58

EC:4.2.1.74

GO:0016508

sp|P51661|DHI2_MOUSE
Corticosteroid 11-beta-dehydrogenase isozyme 2
Search

HSD11B2

0.97	Corticosteroid 11-beta-dehydrogenase isozyme 2

0.55	GO:0007565	female pregnancy
0.50	GO:0055114	oxidation-reduction process
0.43	GO:0008211	glucocorticoid metabolic process
0.42	GO:0002017	regulation of blood volume by renal aldosterone
0.40	GO:0032094	response to food
0.40	GO:0051384	response to glucocorticoid
0.39	GO:0032868	response to insulin
0.39	GO:0001666	response to hypoxia
0.37	GO:0042493	response to drug
0.36	GO:0033555	multicellular organismal response to stress

0.52	GO:0016491	oxidoreductase activity
0.39	GO:0005496	steroid binding
0.37	GO:0051287	NAD binding
0.32	GO:0016829	lyase activity
0.32	GO:0016301	kinase activity

0.40	GO:0005783	endoplasmic reticulum
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.52

EC:1

GO:0016491

sp|P51667|MLRV_MOUSE
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform
Search

MYL2

0.95	Cardiac ventricular myosin light chain-2

0.59	GO:0098735	positive regulation of the force of heart contraction
0.58	GO:0042694	muscle cell fate specification
0.57	GO:0055003	cardiac myofibril assembly
0.55	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.55	GO:0060047	heart contraction
0.55	GO:0048747	muscle fiber development
0.55	GO:0006941	striated muscle contraction
0.54	GO:0030308	negative regulation of cell growth
0.52	GO:0009791	post-embryonic development
0.36	GO:0061049	cell growth involved in cardiac muscle cell development

0.69	GO:0005509	calcium ion binding
0.55	GO:0003785	actin monomer binding
0.35	GO:0032036	myosin heavy chain binding
0.35	GO:0008307	structural constituent of muscle

0.57	GO:0097512	cardiac myofibril
0.51	GO:0015629	actin cytoskeleton
0.40	GO:0031672	A band
0.38	GO:0044430	cytoskeletal part
0.36	GO:0043234	protein complex
0.35	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P51670|CCL9_MOUSE
C-C motif chemokine 9
Search

CCL9

0.46	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.74	GO:0010469	regulation of receptor activity
0.58	GO:0071674	mononuclear cell migration
0.57	GO:0072676	lymphocyte migration
0.57	GO:0097529	myeloid leukocyte migration
0.56	GO:0071347	cellular response to interleukin-1
0.56	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.55	GO:0071356	cellular response to tumor necrosis factor
0.55	GO:0070098	chemokine-mediated signaling pathway

0.84	GO:0008009	chemokine activity
0.57	GO:0048020	CCR chemokine receptor binding
0.38	GO:0004698	calcium-dependent protein kinase C activity
0.38	GO:0016004	phospholipase activator activity
0.37	GO:0042056	chemoattractant activity

0.72	GO:0005615	extracellular space
0.35	GO:0005829	cytosol

0.38

GO:0004698

sp|P51675|CCR1_MOUSE
C-C chemokine receptor type 1
Search

0.97	C-C motif chemokine receptor 1

0.83	GO:0070098	chemokine-mediated signaling pathway
0.79	GO:0006954	inflammatory response
0.70	GO:0006935	chemotaxis
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.69	GO:0006955	immune response
0.65	GO:0090026	positive regulation of monocyte chemotaxis
0.53	GO:0051094	positive regulation of developmental process
0.52	GO:0051240	positive regulation of multicellular organismal process
0.52	GO:2000026	regulation of multicellular organismal development
0.50	GO:0007204	positive regulation of cytosolic calcium ion concentration

0.85	GO:0016493	C-C chemokine receptor activity
0.61	GO:0019957	C-C chemokine binding
0.48	GO:0004435	phosphatidylinositol phospholipase C activity
0.37	GO:0003779	actin binding

0.49	GO:0009897	external side of plasma membrane
0.38	GO:0005768	endosome
0.36	GO:0043025	neuronal cell body
0.34	GO:0005887	integral component of plasma membrane
0.33	GO:0005615	extracellular space

0.48	EC:3.1.4.11	GO:0004435
0.48	KEGG:R03435	GO:0004435

sp|P51676|CC1L1_MOUSE
C-C chemokine receptor 1-like protein 1
Search

0.97	C-C motif chemokine receptor 1

0.82	GO:0070098	chemokine-mediated signaling pathway
0.77	GO:0006954	inflammatory response
0.70	GO:0006935	chemotaxis
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.67	GO:0006955	immune response
0.66	GO:0090026	positive regulation of monocyte chemotaxis
0.53	GO:0051094	positive regulation of developmental process
0.53	GO:0051240	positive regulation of multicellular organismal process
0.53	GO:2000026	regulation of multicellular organismal development
0.53	GO:0007204	positive regulation of cytosolic calcium ion concentration

0.85	GO:0016493	C-C chemokine receptor activity
0.61	GO:0019957	C-C chemokine binding
0.48	GO:0004435	phosphatidylinositol phospholipase C activity
0.40	GO:0031727	CCR2 chemokine receptor binding
0.37	GO:0003779	actin binding
0.36	GO:0015026	coreceptor activity
0.34	GO:0104005	hijacked molecular function
0.33	GO:0019901	protein kinase binding
0.33	GO:0019958	C-X-C chemokine binding
0.33	GO:0042803	protein homodimerization activity

0.50	GO:0009897	external side of plasma membrane
0.38	GO:0005768	endosome
0.37	GO:0043025	neuronal cell body
0.35	GO:0005887	integral component of plasma membrane
0.34	GO:0030425	dendrite
0.33	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005615	extracellular space
0.33	GO:0005829	cytosol

0.48	EC:3.1.4.11	GO:0004435
0.48	KEGG:R03435	GO:0004435

sp|P51678|CCR3_MOUSE
Probable C-C chemokine receptor type 3
Search

CCR3

0.97	C-C motif chemokine receptor 3

0.82	GO:0070098	chemokine-mediated signaling pathway
0.78	GO:0006954	inflammatory response
0.69	GO:0006935	chemotaxis
0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.67	GO:0090026	positive regulation of monocyte chemotaxis
0.64	GO:0006955	immune response
0.57	GO:0051094	positive regulation of developmental process
0.57	GO:0051240	positive regulation of multicellular organismal process
0.56	GO:2000026	regulation of multicellular organismal development
0.54	GO:0001938	positive regulation of endothelial cell proliferation

0.85	GO:0016493	C-C chemokine receptor activity
0.67	GO:0019957	C-C chemokine binding
0.48	GO:0004435	phosphatidylinositol phospholipase C activity
0.40	GO:0031727	CCR2 chemokine receptor binding
0.37	GO:0003779	actin binding
0.34	GO:0042803	protein homodimerization activity

0.51	GO:0009897	external side of plasma membrane
0.39	GO:0005768	endosome
0.37	GO:0043025	neuronal cell body
0.35	GO:0005887	integral component of plasma membrane
0.34	GO:0005615	extracellular space
0.34	GO:0030425	dendrite
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005829	cytosol

0.48	EC:3.1.4.11	GO:0004435
0.48	KEGG:R03435	GO:0004435

sp|P51680|CCR4_MOUSE
C-C chemokine receptor type 4
Search

CCR4

0.97	C-C motif chemokine receptor 4

0.84	GO:0070098	chemokine-mediated signaling pathway
0.79	GO:0006954	inflammatory response
0.72	GO:0006955	immune response
0.71	GO:0006935	chemotaxis
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.59	GO:0002507	tolerance induction
0.57	GO:0050921	positive regulation of chemotaxis
0.57	GO:0071677	positive regulation of mononuclear cell migration
0.57	GO:0090025	regulation of monocyte chemotaxis
0.55	GO:0001764	neuron migration

0.85	GO:0016493	C-C chemokine receptor activity
0.38	GO:0019957	C-C chemokine binding
0.35	GO:0004535	poly(A)-specific ribonuclease activity
0.34	GO:0003779	actin binding
0.33	GO:0008270	zinc ion binding

0.55	GO:0009897	external side of plasma membrane
0.41	GO:0043025	neuronal cell body
0.35	GO:0005768	endosome
0.34	GO:0005887	integral component of plasma membrane

0.35

EC:3.1.13.4

GO:0004535

sp|P51682|CCR5_MOUSE
C-C chemokine receptor type 5
Search

CCR5

0.89	G-protein coupled chemokine receptor

0.83	GO:0070098	chemokine-mediated signaling pathway
0.80	GO:0006954	inflammatory response
0.73	GO:0006955	immune response
0.71	GO:0006935	chemotaxis
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.46	GO:0090026	positive regulation of monocyte chemotaxis
0.46	GO:0001974	blood vessel remodeling
0.45	GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.45	GO:0070723	response to cholesterol
0.44	GO:2000464	positive regulation of astrocyte chemotaxis

0.85	GO:0016493	C-C chemokine receptor activity
0.50	GO:0019957	C-C chemokine binding
0.44	GO:0031727	CCR2 chemokine receptor binding
0.41	GO:0003779	actin binding
0.36	GO:0042803	protein homodimerization activity
0.35	GO:0104005	hijacked molecular function
0.35	GO:0015026	coreceptor activity
0.34	GO:0004435	phosphatidylinositol phospholipase C activity
0.34	GO:0019901	protein kinase binding

0.47	GO:0009897	external side of plasma membrane
0.41	GO:0005768	endosome
0.37	GO:0043204	perikaryon
0.36	GO:0030425	dendrite
0.36	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005829	cytosol
0.35	GO:0005887	integral component of plasma membrane

0.34	EC:3.1.4.11	GO:0004435
0.34	KEGG:R03435	GO:0004435

sp|P51683|CCR2_MOUSE
C-C chemokine receptor type 2
Search

CCR5

0.86	C-C motif chemokine receptor 2

0.83	GO:0070098	chemokine-mediated signaling pathway
0.79	GO:0006954	inflammatory response
0.73	GO:0006955	immune response
0.70	GO:0006935	chemotaxis
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.61	GO:0090026	positive regulation of monocyte chemotaxis
0.61	GO:0001974	blood vessel remodeling
0.54	GO:2000464	positive regulation of astrocyte chemotaxis
0.52	GO:0043310	negative regulation of eosinophil degranulation
0.52	GO:2000473	positive regulation of hematopoietic stem cell migration

0.85	GO:0016493	C-C chemokine receptor activity
0.56	GO:0019957	C-C chemokine binding
0.53	GO:0031727	CCR2 chemokine receptor binding
0.42	GO:0003779	actin binding
0.37	GO:0042803	protein homodimerization activity
0.34	GO:0019901	protein kinase binding

0.52	GO:0009897	external side of plasma membrane
0.42	GO:0005768	endosome
0.38	GO:0043204	perikaryon
0.37	GO:0030425	dendrite
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005829	cytosol
0.34	GO:0005887	integral component of plasma membrane

sp|P51791|CLCN3_MOUSE
H(+)/Cl(-) exchange transporter 3
Search

CLCN3

0.51	Chloride channel protein (Fragment)

0.76	GO:1902476	chloride transmembrane transport
0.56	GO:0045794	negative regulation of cell volume

0.78	GO:0005247	voltage-gated chloride channel activity
0.57	GO:0072320	volume-sensitive chloride channel activity
0.53	GO:0030165	PDZ domain binding
0.48	GO:0046982	protein heterodimerization activity

0.54	GO:0042581	specific granule
0.52	GO:0045335	phagocytic vesicle
0.51	GO:0005770	late endosome
0.51	GO:0005769	early endosome
0.51	GO:0008021	synaptic vesicle
0.51	GO:0009897	external side of plasma membrane
0.49	GO:0012506	vesicle membrane
0.48	GO:0005794	Golgi apparatus
0.40	GO:0005887	integral component of plasma membrane

sp|P51807|DYLT1_MOUSE
Dynein light chain Tctex-type 1
Search

DYNLT1

0.93	Dynein light chain Tctex-type 1

0.85	GO:0019060	intracellular transport of viral protein in host cell
0.50	GO:0000132	establishment of mitotic spindle orientation
0.50	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.49	GO:0050768	negative regulation of neurogenesis
0.47	GO:0010976	positive regulation of neuron projection development
0.47	GO:1905709	negative regulation of membrane permeability
0.46	GO:0035022	positive regulation of Rac protein signal transduction
0.45	GO:0046902	regulation of mitochondrial membrane permeability
0.44	GO:0016358	dendrite development
0.44	GO:0048468	cell development

0.73	GO:0042802	identical protein binding
0.46	GO:0003774	motor activity
0.44	GO:0008022	protein C-terminus binding
0.42	GO:0031681	G-protein beta-subunit binding
0.41	GO:0030742	GTP-dependent protein binding
0.39	GO:0051959	dynein light intermediate chain binding
0.39	GO:0097718	disordered domain specific binding
0.39	GO:0045505	dynein intermediate chain binding
0.36	GO:0046983	protein dimerization activity

0.82	GO:0005868	cytoplasmic dynein complex
0.82	GO:0005881	cytoplasmic microtubule
0.78	GO:0099503	secretory vesicle
0.62	GO:0043657	host cell
0.47	GO:0030426	growth cone
0.47	GO:0005819	spindle
0.46	GO:0044297	cell body
0.46	GO:0033267	axon part
0.45	GO:0005794	Golgi apparatus
0.44	GO:0030027	lamellipodium

sp|P51827|AFF3_MOUSE
AF4/FMR2 family member 3
Search

0.96	AF4/FMR2 family member 3 isoform A

0.85	GO:0035116	embryonic hindlimb morphogenesis
0.82	GO:0034612	response to tumor necrosis factor
0.48	GO:0035063	nuclear speck organization
0.44	GO:0043484	regulation of RNA splicing
0.39	GO:0007611	learning or memory
0.38	GO:0006351	transcription, DNA-templated
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010629	negative regulation of gene expression

0.71	GO:0003690	double-stranded DNA binding
0.40	GO:0002151	G-quadruplex RNA binding
0.30	GO:0140110	transcription regulator activity

0.76	GO:0016604	nuclear body
0.66	GO:0005829	cytosol

sp|P51829|ADCY7_MOUSE
Adenylate cyclase type 7
Search

ADCY7

0.94	Adenylate cyclase type 7

0.78	GO:0006171	cAMP biosynthetic process
0.62	GO:0035556	intracellular signal transduction
0.58	GO:0071361	cellular response to ethanol
0.50	GO:0006182	cGMP biosynthetic process
0.47	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.41	GO:0060135	maternal process involved in female pregnancy
0.40	GO:0007190	activation of adenylate cyclase activity
0.38	GO:0034199	activation of protein kinase A activity
0.37	GO:0071377	cellular response to glucagon stimulus
0.37	GO:0003091	renal water homeostasis

0.78	GO:0004016	adenylate cyclase activity
0.51	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0004383	guanylate cyclase activity
0.46	GO:0005080	protein kinase C binding
0.35	GO:0046872	metal ion binding
0.33	GO:0004672	protein kinase activity

0.55	GO:0005886	plasma membrane
0.52	GO:0008074	guanylate cyclase complex, soluble
0.44	GO:0030425	dendrite
0.30	GO:0016021	integral component of membrane

0.78

EC:4.6.1.1

GO:0004016

sp|P51830|ADCY9_MOUSE
Adenylate cyclase type 9
Search

ADCY9

0.91	Adenylate cyclase type 9

0.76	GO:0009190	cyclic nucleotide biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.58	GO:0071875	adrenergic receptor signaling pathway
0.57	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.56	GO:0046058	cAMP metabolic process
0.50	GO:0009152	purine ribonucleotide biosynthetic process
0.47	GO:0046068	cGMP metabolic process
0.37	GO:0034199	activation of protein kinase A activity
0.36	GO:0071377	cellular response to glucagon stimulus
0.36	GO:0003091	renal water homeostasis

0.75	GO:0016849	phosphorus-oxygen lyase activity
0.57	GO:0009975	cyclase activity
0.52	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0008144	drug binding
0.35	GO:0046872	metal ion binding
0.34	GO:0043168	anion binding

0.49	GO:0005887	integral component of plasma membrane
0.49	GO:0008074	guanylate cyclase complex, soluble
0.39	GO:0030425	dendrite
0.39	GO:0030424	axon

0.75

EC:4.6

GO:0016849

sp|P51855|GSHB_MOUSE
Glutathione synthetase
Search

GSS

0.53	Glutathione synthetase

0.78	GO:0006750	glutathione biosynthetic process
0.58	GO:0046686	response to cadmium ion
0.41	GO:0043200	response to amino acid
0.41	GO:0034612	response to tumor necrosis factor
0.40	GO:0007568	aging
0.40	GO:0006520	cellular amino acid metabolic process
0.40	GO:0009410	response to xenobiotic stimulus
0.40	GO:0031667	response to nutrient levels
0.34	GO:0007399	nervous system development
0.34	GO:0006979	response to oxidative stress

0.80	GO:0004363	glutathione synthase activity
0.79	GO:0043295	glutathione binding
0.69	GO:0042803	protein homodimerization activity
0.60	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0042165	neurotransmitter binding
0.39	GO:0016597	amino acid binding

0.44	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome

0.80	EC:6.3.2.3	GO:0004363
0.80	KEGG:R00497	GO:0004363

sp|P51859|HDGF_MOUSE
Hepatoma-derived growth factor
Search

HDGF

0.95	Hepatoma-derived growth factor

0.69	GO:0000122	negative regulation of transcription by RNA polymerase II
0.51	GO:0010469	regulation of receptor activity
0.45	GO:0007026	negative regulation of microtubule depolymerization
0.44	GO:0046785	microtubule polymerization
0.44	GO:0008283	cell proliferation
0.43	GO:0030307	positive regulation of cell growth
0.43	GO:0031175	neuron projection development
0.42	GO:0036498	IRE1-mediated unfolded protein response
0.41	GO:0006351	transcription, DNA-templated
0.41	GO:0034504	protein localization to nucleus

0.79	GO:0001222	transcription corepressor binding
0.76	GO:0001106	RNA polymerase II transcription corepressor activity
0.52	GO:0008083	growth factor activity
0.51	GO:0008201	heparin binding
0.43	GO:0008092	cytoskeletal protein binding
0.41	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.41	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0003682	chromatin binding
0.39	GO:1901265	nucleoside phosphate binding
0.39	GO:0036094	small molecule binding

0.71	GO:0017053	transcriptional repressor complex
0.68	GO:0005615	extracellular space
0.66	GO:0031012	extracellular matrix
0.63	GO:0005654	nucleoplasm
0.40	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P51860|NP1L2_MOUSE
Nucleosome assembly protein 1-like 2
Search

NAP1L2

0.73	Brain-specific protein, X-linked

0.79	GO:0006334	nucleosome assembly
0.57	GO:0071442	positive regulation of histone H3-K14 acetylation
0.56	GO:2000035	regulation of stem cell division
0.56	GO:2000617	positive regulation of histone H3-K9 acetylation
0.52	GO:0045666	positive regulation of neuron differentiation
0.39	GO:0002244	hematopoietic progenitor cell differentiation
0.35	GO:0035041	sperm chromatin decondensation
0.35	GO:0035092	sperm chromatin condensation
0.34	GO:0000723	telomere maintenance
0.34	GO:0006338	chromatin remodeling

0.52	GO:0042393	histone binding
0.51	GO:0003682	chromatin binding
0.36	GO:0044877	macromolecular complex binding
0.33	GO:0015485	cholesterol binding
0.33	GO:0004970	ionotropic glutamate receptor activity
0.33	GO:0046982	protein heterodimerization activity
0.32	GO:0008134	transcription factor binding
0.32	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.33	GO:0000786	nucleosome
0.30	GO:0016021	integral component of membrane

sp|P51863|VA0D1_MOUSE
V-type proton ATPase subunit d 1
Search

ATP6V0D1

0.68	V-type proton ATPase subunit

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.54	GO:0036295	cellular response to increased oxygen levels
0.49	GO:0030003	cellular cation homeostasis
0.48	GO:0055072	iron ion homeostasis
0.47	GO:0035675	neuromast hair cell development
0.46	GO:0045851	pH reduction
0.46	GO:0008057	eye pigment granule organization
0.46	GO:0039022	pronephric duct development
0.46	GO:0003406	retinal pigment epithelium development
0.46	GO:0070986	left/right axis specification

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.51	GO:0036442	proton-exporting ATPase activity
0.49	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.42	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.36	GO:0032403	protein complex binding

0.79	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.53	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.52	GO:0005769	early endosome
0.50	GO:0005813	centrosome
0.46	GO:0005765	lysosomal membrane
0.40	GO:0016324	apical plasma membrane
0.38	GO:0043679	axon terminus
0.37	GO:0008021	synaptic vesicle
0.36	GO:0070062	extracellular exosome
0.35	GO:0030670	phagocytic vesicle membrane

sp|P51865|TDGF1_MOUSE
Teratocarcinoma-derived growth factor
Search

TDGF1

0.95	Teratocarcinoma-derived growth factor

0.71	GO:0010469	regulation of receptor activity
0.66	GO:0035729	cellular response to hepatocyte growth factor stimulus
0.66	GO:0002042	cell migration involved in sprouting angiogenesis
0.65	GO:0071354	cellular response to interleukin-6
0.65	GO:0071364	cellular response to epidermal growth factor stimulus
0.63	GO:0071346	cellular response to interferon-gamma
0.63	GO:0010595	positive regulation of endothelial cell migration
0.63	GO:0000187	activation of MAPK activity
0.62	GO:0071356	cellular response to tumor necrosis factor
0.62	GO:0007507	heart development

0.74	GO:0008083	growth factor activity
0.44	GO:0038100	nodal binding
0.44	GO:0070698	type I activin receptor binding
0.42	GO:0017147	Wnt-protein binding
0.42	GO:0015026	coreceptor activity
0.41	GO:0005509	calcium ion binding
0.35	GO:0004550	nucleoside diphosphate kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0032555	purine ribonucleotide binding

0.61	GO:0016324	apical plasma membrane
0.60	GO:0098857	membrane microdomain
0.60	GO:0009986	cell surface
0.56	GO:0005615	extracellular space
0.42	GO:0019897	extrinsic component of plasma membrane
0.42	GO:0098552	side of membrane
0.41	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0031225	anchored component of membrane
0.39	GO:0005794	Golgi apparatus
0.37	GO:0005634	nucleus

0.35

EC:2.7.4.6

GO:0004550

sp|P51879|ONCO_MOUSE
Oncomodulin
Search

0.89	Parvalbumin alpha

0.40	GO:1905591	regulation of optical nerve axon regeneration
0.39	GO:1902336	positive regulation of retinal ganglion cell axon guidance
0.39	GO:0048687	positive regulation of sprouting of injured axon
0.38	GO:0048690	regulation of axon extension involved in regeneration
0.38	GO:0070207	protein homotrimerization
0.38	GO:0045773	positive regulation of axon extension
0.37	GO:0051289	protein homotetramerization
0.37	GO:0051480	regulation of cytosolic calcium ion concentration
0.37	GO:0009611	response to wounding
0.34	GO:0010941	regulation of cell death

0.70	GO:0005509	calcium ion binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0046982	protein heterodimerization activity

0.40	GO:0030424	axon
0.36	GO:0005615	extracellular space
0.36	GO:0099512	supramolecular fiber
0.36	GO:0031982	vesicle
0.35	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus
0.34	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|P51880|FABP7_MOUSE
Fatty acid-binding protein, brain
Search

FABP7

0.81	Fatty acid-binding protein, retina

0.53	GO:0060134	prepulse inhibition
0.53	GO:0021846	cell proliferation in forebrain
0.48	GO:0022008	neurogenesis
0.38	GO:0050673	epithelial cell proliferation
0.35	GO:0019433	triglyceride catabolic process
0.35	GO:0003407	neural retina development
0.35	GO:2001245	regulation of phosphatidylcholine biosynthetic process
0.34	GO:0055091	phospholipid homeostasis
0.34	GO:0044539	long-chain fatty acid import
0.34	GO:0046320	regulation of fatty acid oxidation

0.72	GO:0008289	lipid binding
0.36	GO:0033293	monocarboxylic acid binding
0.34	GO:0005515	protein binding
0.33	GO:0016787	hydrolase activity

0.50	GO:0043025	neuronal cell body
0.48	GO:0005911	cell-cell junction
0.45	GO:0042995	cell projection
0.40	GO:0071944	cell periphery
0.35	GO:0005634	nucleus
0.35	GO:0005829	cytosol
0.33	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016787

sp|P51881|ADT2_MOUSE
ADP/ATP translocase 2
Search

SLC25A5

0.82	Adenine nucleotide translocase

0.55	GO:0046902	regulation of mitochondrial membrane permeability
0.55	GO:0055085	transmembrane transport
0.53	GO:0010823	negative regulation of mitochondrion organization
0.51	GO:2001234	negative regulation of apoptotic signaling pathway
0.50	GO:0051051	negative regulation of transport
0.49	GO:0008284	positive regulation of cell proliferation
0.49	GO:1990823	response to leukemia inhibitory factor
0.48	GO:0015866	ADP transport
0.47	GO:0015867	ATP transport
0.46	GO:0071345	cellular response to cytokine stimulus

0.57	GO:0022857	transmembrane transporter activity
0.48	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0003723	RNA binding

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.54	GO:0071817	MMXD complex
0.50	GO:0042645	mitochondrial nucleoid
0.49	GO:0043209	myelin sheath
0.38	GO:0045121	membrane raft
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.33	GO:0005887	integral component of plasma membrane

sp|P51885|LUM_MOUSE
Lumican
Search

LUM

0.97	Keratan sulfate proteoglycan lumican

0.83	GO:0030199	collagen fibril organization
0.73	GO:0007601	visual perception
0.59	GO:0032914	positive regulation of transforming growth factor beta1 production
0.51	GO:0045944	positive regulation of transcription by RNA polymerase II
0.48	GO:0007409	axonogenesis
0.42	GO:0048596	embryonic camera-type eye morphogenesis
0.38	GO:0051216	cartilage development
0.38	GO:0070848	response to growth factor
0.37	GO:0042340	keratan sulfate catabolic process
0.37	GO:0014070	response to organic cyclic compound

0.57	GO:0005518	collagen binding
0.35	GO:0005201	extracellular matrix structural constituent
0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.75	GO:0005578	proteinaceous extracellular matrix
0.55	GO:0005615	extracellular space
0.54	GO:0044420	extracellular matrix component
0.53	GO:0005581	collagen trimer
0.50	GO:0099512	supramolecular fiber
0.37	GO:0043202	lysosomal lumen
0.37	GO:0005796	Golgi lumen
0.37	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

sp|P51906|EAA3_MOUSE
Excitatory amino acid transporter 3
Search

SLC1A1

0.45	Amino acid transporter

0.61	GO:1903712	cysteine transmembrane transport
0.61	GO:0140009	L-aspartate import across plasma membrane
0.61	GO:0140016	D-aspartate import across plasma membrane
0.60	GO:0098712	L-glutamate import across plasma membrane
0.57	GO:0010460	positive regulation of heart rate
0.53	GO:1902476	chloride transmembrane transport
0.52	GO:0051260	protein homooligomerization
0.36	GO:0014047	glutamate secretion
0.34	GO:0007268	chemical synaptic transmission

0.72	GO:0015293	symporter activity
0.61	GO:0033229	cysteine transmembrane transporter activity
0.55	GO:0005313	L-glutamate transmembrane transporter activity
0.53	GO:0015108	chloride transmembrane transporter activity
0.51	GO:0015081	sodium ion transmembrane transporter activity
0.49	GO:0022853	active ion transmembrane transporter activity
0.40	GO:0016595	glutamate binding
0.35	GO:0005515	protein binding
0.35	GO:0046872	metal ion binding

0.55	GO:0016324	apical plasma membrane
0.48	GO:0005887	integral component of plasma membrane
0.37	GO:0070062	extracellular exosome

sp|P51908|ABEC1_MOUSE
C->U-editing enzyme APOBEC-1
Search

APOBEC1

0.96	Apolipoprotein B mRNA editing enzyme catalytic subunit 1

0.69	GO:0090310	negative regulation of methylation-dependent chromatin silencing
0.65	GO:0090209	negative regulation of triglyceride metabolic process
0.64	GO:0016554	cytidine to uridine editing
0.64	GO:0080111	DNA demethylation
0.63	GO:0048255	mRNA stabilization
0.62	GO:0010332	response to gamma radiation
0.59	GO:0006641	triglyceride metabolic process
0.58	GO:0016556	mRNA modification
0.57	GO:0042953	lipoprotein transport
0.56	GO:0042127	regulation of cell proliferation

0.71	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
0.63	GO:0008270	zinc ion binding
0.63	GO:0017091	AU-rich element binding
0.44	GO:0019904	protein domain specific binding
0.44	GO:0003729	mRNA binding
0.43	GO:0008047	enzyme activator activity
0.43	GO:0043021	ribonucleoprotein complex binding
0.43	GO:0019239	deaminase activity
0.35	GO:0008083	growth factor activity

0.42	GO:0005737	cytoplasm
0.39	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0005576	extracellular region
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.71

EC:3.5.4

GO:0016814

sp|P51910|APOD_MOUSE
Apolipoprotein D
Search

APOD

0.87	Apolipoprotein D

0.77	GO:0007568	aging
0.71	GO:0006869	lipid transport
0.65	GO:0034443	negative regulation of lipoprotein oxidation
0.65	GO:0060587	regulation of lipoprotein lipid oxidation
0.65	GO:2000098	negative regulation of smooth muscle cell-matrix adhesion
0.64	GO:2000405	negative regulation of T cell migration
0.63	GO:0071638	negative regulation of monocyte chemotactic protein-1 production
0.63	GO:1900016	negative regulation of cytokine production involved in inflammatory response
0.63	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway
0.62	GO:0051895	negative regulation of focal adhesion assembly

0.69	GO:0008289	lipid binding
0.58	GO:0043178	alcohol binding
0.46	GO:0031409	pigment binding
0.38	GO:0097159	organic cyclic compound binding
0.37	GO:0005215	transporter activity
0.36	GO:0004864	protein phosphatase inhibitor activity
0.34	GO:0016301	kinase activity
0.34	GO:0003995	acyl-CoA dehydrogenase activity
0.34	GO:0008242	omega peptidase activity
0.33	GO:0005515	protein binding

0.56	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0005615	extracellular space
0.50	GO:0043025	neuronal cell body
0.50	GO:0030425	dendrite
0.49	GO:0022626	cytosolic ribosome
0.46	GO:0005783	endoplasmic reticulum
0.37	GO:1903561	extracellular vesicle
0.35	GO:0044462	external encapsulating structure part
0.35	GO:0019867	outer membrane
0.34	GO:0030313	cell envelope

0.34

EC:1.3.99.3

GO:0003995

sp|P51912|AAAT_MOUSE
Neutral amino acid transporter B(0)
Search

SLC1A5

0.45	Amino acid transporter

0.55	GO:0055085	transmembrane transport
0.45	GO:0015825	L-serine transport
0.43	GO:0036229	L-glutamine import
0.43	GO:0010585	glutamine secretion
0.41	GO:0034589	hydroxyproline transport
0.41	GO:0015811	L-cystine transport
0.41	GO:0015808	L-alanine transport
0.39	GO:0015826	threonine transport
0.39	GO:0050890	cognition
0.39	GO:0015824	proline transport

0.72	GO:0015293	symporter activity
0.45	GO:0015194	L-serine transmembrane transporter activity
0.41	GO:0034590	L-hydroxyproline transmembrane transporter activity
0.41	GO:0015184	L-cystine transmembrane transporter activity
0.41	GO:0015180	L-alanine transmembrane transporter activity
0.40	GO:0015195	L-threonine transmembrane transporter activity
0.39	GO:0015193	L-proline transmembrane transporter activity
0.38	GO:0005254	chloride channel activity
0.35	GO:0015186	L-glutamine transmembrane transporter activity
0.35	GO:0104005	hijacked molecular function

0.42	GO:0005886	plasma membrane
0.42	GO:0042470	melanosome
0.38	GO:0005882	intermediate filament
0.38	GO:0005813	centrosome
0.38	GO:0070062	extracellular exosome
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.30	GO:0016021	integral component of membrane

sp|P51942|MATN1_MOUSE
Cartilage matrix protein
Search

MATN1

0.91	cartilage matrix protein isoform X1

0.61	GO:0003429	growth plate cartilage chondrocyte morphogenesis
0.55	GO:0030500	regulation of bone mineralization
0.37	GO:1901031	regulation of response to reactive oxygen species
0.36	GO:0030198	extracellular matrix organization
0.35	GO:0006461	protein complex assembly

0.80	GO:0005201	extracellular matrix structural constituent
0.69	GO:0005509	calcium ion binding
0.36	GO:0005515	protein binding
0.33	GO:0003677	DNA binding

0.74	GO:0005578	proteinaceous extracellular matrix
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P51943|CCNA2_MOUSE
Cyclin-A2
Search

0.62

Cyclin A

0.59	GO:0000086	G2/M transition of mitotic cell cycle
0.58	GO:0016572	histone phosphorylation
0.58	GO:0044843	cell cycle G1/S phase transition
0.56	GO:0007265	Ras protein signal transduction
0.52	GO:0045893	positive regulation of transcription, DNA-templated
0.52	GO:0051726	regulation of cell cycle
0.45	GO:0007423	sensory organ development
0.43	GO:0071373	cellular response to luteinizing hormone stimulus
0.43	GO:0071314	cellular response to cocaine
0.42	GO:1990314	cellular response to insulin-like growth factor stimulus

0.57	GO:0097472	cyclin-dependent protein kinase activity
0.54	GO:0019901	protein kinase binding
0.53	GO:0019904	protein domain specific binding
0.35	GO:0001103	RNA polymerase II repressing transcription factor binding

0.62	GO:0097124	cyclin A2-CDK2 complex
0.61	GO:0005634	nucleus
0.49	GO:0005829	cytosol
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.41	GO:0097123	cyclin A1-CDK2 complex
0.39	GO:0015630	microtubule cytoskeleton
0.35	GO:0001750	photoreceptor outer segment
0.35	GO:0034464	BBSome
0.35	GO:0097014	ciliary plasm

sp|P51944|CCNF_MOUSE
Cyclin-F
Search

CCNF

0.97

Cyclin-F

0.71	GO:0051726	regulation of cell cycle
0.59	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.59	GO:0000320	re-entry into mitotic cell cycle
0.57	GO:0070507	regulation of microtubule cytoskeleton organization
0.57	GO:0051494	negative regulation of cytoskeleton organization
0.56	GO:0001890	placenta development
0.53	GO:0016567	protein ubiquitination
0.39	GO:0051301	cell division
0.35	GO:0043687	post-translational protein modification
0.35	GO:0055085	transmembrane transport

0.38	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0008144	drug binding
0.34	GO:0005515	protein binding
0.33	GO:0017127	cholesterol transporter activity
0.33	GO:0005543	phospholipid binding
0.32	GO:1901681	sulfur compound binding

0.60	GO:0005634	nucleus
0.59	GO:0019005	SCF ubiquitin ligase complex
0.58	GO:0005814	centriole
0.55	GO:0005813	centrosome
0.53	GO:0030054	cell junction
0.35	GO:0005829	cytosol
0.34	GO:0034359	mature chylomicron
0.34	GO:0034363	intermediate-density lipoprotein particle
0.34	GO:0034362	low-density lipoprotein particle
0.33	GO:0031983	vesicle lumen

0.38

GO:0004842

sp|P51945|CCNG1_MOUSE
Cyclin-G1
Search

0.73	GO:0051726	regulation of cell cycle
0.38	GO:0051301	cell division
0.38	GO:0007049	cell cycle
0.35	GO:0006949	syncytium formation
0.35	GO:0007420	brain development
0.34	GO:0043066	negative regulation of apoptotic process
0.34	GO:0010243	response to organonitrogen compound
0.34	GO:0071900	regulation of protein serine/threonine kinase activity
0.33	GO:0006974	cellular response to DNA damage stimulus
0.33	GO:0015991	ATP hydrolysis coupled proton transport

0.33	GO:0005515	protein binding
0.33	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005634	nucleus
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.35	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P51949|MAT1_MOUSE
CDK-activating kinase assembly factor MAT1
Search

MNAT1

0.88	MNAT CDK-activating kinase assembly factor 1

0.85	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.73	GO:0006289	nucleotide-excision repair
0.57	GO:0007512	adult heart development
0.56	GO:0021591	ventricular system development
0.55	GO:0051592	response to calcium ion
0.51	GO:0016310	phosphorylation
0.51	GO:0006366	transcription by RNA polymerase II
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0036211	protein modification process
0.43	GO:0044267	cellular protein metabolic process

0.85	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity
0.57	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.55	GO:0047485	protein N-terminus binding
0.48	GO:0008094	DNA-dependent ATPase activity
0.43	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0000990	transcription factor activity, core RNA polymerase binding
0.33	GO:0003735	structural constituent of ribosome

0.83	GO:0005675	holo TFIIH complex
0.48	GO:0005829	cytosol
0.36	GO:0042585	germinal vesicle
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.57

EC:2.7.11.23

GO:0008353

sp|P51954|NEK1_MOUSE
Serine/threonine-protein kinase Nek1
Search

NEK1

0.80	NIMA (Never in mitosis gene a)-related kinase 1

0.66	GO:0042769	DNA damage response, detection of DNA damage
0.63	GO:0006468	protein phosphorylation
0.63	GO:0060271	cilium assembly
0.51	GO:0031098	stress-activated protein kinase signaling cascade
0.50	GO:0032147	activation of protein kinase activity
0.48	GO:0007346	regulation of mitotic cell cycle
0.48	GO:0042981	regulation of apoptotic process
0.47	GO:1904888	cranial skeletal system development
0.42	GO:2000001	regulation of DNA damage checkpoint
0.41	GO:0035264	multicellular organism growth

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0071889	14-3-3 protein binding

0.64	GO:0000242	pericentriolar material
0.48	GO:0005634	nucleus

sp|P51960|MYBA_MOUSE
Myb-related protein A
Search

MYBL1

0.97	MYB proto-oncogene like 1

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0051254	positive regulation of RNA metabolic process
0.53	GO:0010557	positive regulation of macromolecule biosynthetic process
0.53	GO:0031328	positive regulation of cellular biosynthetic process
0.52	GO:0006366	transcription by RNA polymerase II
0.47	GO:0000278	mitotic cell cycle
0.47	GO:0030154	cell differentiation
0.42	GO:1990511	piRNA biosynthetic process

0.56	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.32	GO:0071987	WD40-repeat domain binding

0.43	GO:0005634	nucleus
0.33	GO:0000785	chromatin
0.31	GO:0005829	cytosol
0.31	GO:0043233	organelle lumen
0.30	GO:0016020	membrane

sp|P52019|ERG1_MOUSE
Squalene monooxygenase
Search

SQLE

0.85	Squalene monooxygenase

0.53	GO:0055114	oxidation-reduction process
0.50	GO:0008203	cholesterol metabolic process
0.47	GO:0016126	sterol biosynthetic process
0.39	GO:0010033	response to organic substance
0.36	GO:0045540	regulation of cholesterol biosynthetic process
0.35	GO:1902653	secondary alcohol biosynthetic process
0.34	GO:0006725	cellular aromatic compound metabolic process
0.33	GO:0009414	response to water deprivation
0.33	GO:0008204	ergosterol metabolic process
0.33	GO:0044108	cellular alcohol biosynthetic process

0.85	GO:0004506	squalene monooxygenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.32	GO:0008144	drug binding

0.44	GO:0005783	endoplasmic reticulum
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.35	GO:0031090	organelle membrane
0.33	GO:0005811	lipid droplet
0.30	GO:0016021	integral component of membrane

0.85	EC:1.14.13.132	GO:0004506
0.85	KEGG:R02874	GO:0004506

sp|P52187|KCJ12_MOUSE
ATP-sensitive inward rectifier potassium channel 12
Search

KCNJ12

0.80	Inwardly-rectifying potassium channel

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.42	GO:0098660	inorganic ion transmembrane transport
0.40	GO:0051289	protein homotetramerization
0.36	GO:0061337	cardiac conduction
0.35	GO:0006936	muscle contraction

0.84	GO:0005242	inward rectifier potassium channel activity
0.43	GO:0030165	PDZ domain binding

0.44	GO:0005887	integral component of plasma membrane
0.41	GO:0016323	basolateral plasma membrane
0.35	GO:0030315	T-tubule
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.33	GO:0045211	postsynaptic membrane
0.33	GO:0034705	potassium channel complex
0.33	GO:0030659	cytoplasmic vesicle membrane
0.33	GO:0030054	cell junction

sp|P52189|KCNJ4_MOUSE
Inward rectifier potassium channel 4
Search

KCNJ4

0.90	ATP-sensitive inward rectifier potassium channel 12

0.74	GO:0034765	regulation of ion transmembrane transport
0.69	GO:0006813	potassium ion transport
0.59	GO:0098655	cation transmembrane transport
0.37	GO:0098660	inorganic ion transmembrane transport
0.36	GO:0051289	protein homotetramerization
0.36	GO:0071260	cellular response to mechanical stimulus
0.36	GO:0061337	cardiac conduction

0.80	GO:0005242	inward rectifier potassium channel activity
0.44	GO:0030165	PDZ domain binding

0.44	GO:0016323	basolateral plasma membrane
0.40	GO:0045211	postsynaptic membrane
0.39	GO:0030659	cytoplasmic vesicle membrane
0.39	GO:0030054	cell junction
0.38	GO:0005887	integral component of plasma membrane
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.35	GO:0034705	potassium channel complex

sp|P52194|CLGN_MOUSE
Calmegin
Search

CLGN

0.84	Testis tissue sperm-binding protein Li 79P

0.69	GO:0006457	protein folding
0.53	GO:0007339	binding of sperm to zona pellucida
0.46	GO:0006461	protein complex assembly
0.46	GO:0048488	synaptic vesicle endocytosis
0.42	GO:0072583	clathrin-dependent endocytosis
0.36	GO:0032501	multicellular organismal process
0.36	GO:0032502	developmental process
0.35	GO:0005975	carbohydrate metabolic process
0.35	GO:0051321	meiotic cell cycle
0.34	GO:0007155	cell adhesion

0.71	GO:0051082	unfolded protein binding
0.70	GO:0005509	calcium ion binding
0.53	GO:0044183	protein binding involved in protein folding
0.37	GO:0016758	transferase activity, transferring hexosyl groups
0.36	GO:0034185	apolipoprotein binding
0.36	GO:0035255	ionotropic glutamate receptor binding
0.35	GO:0030246	carbohydrate binding
0.33	GO:0003777	microtubule motor activity
0.32	GO:0005198	structural molecule activity

0.70	GO:0005783	endoplasmic reticulum
0.49	GO:0005635	nuclear envelope
0.47	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.45	GO:0031984	organelle subcompartment
0.44	GO:0044233	ER-mitochondrion membrane contact site
0.44	GO:0043209	myelin sheath
0.43	GO:0045202	synapse
0.37	GO:0042470	melanosome
0.36	GO:0032839	dendrite cytoplasm
0.36	GO:0044309	neuron spine

0.37

GO:0016758

sp|P52196|THTR_MOUSE
Thiosulfate sulfurtransferase
Search

TST

0.51	Thiosulfate sulfurtransferase

0.62	GO:0035928	rRNA import into mitochondrion
0.54	GO:0030855	epithelial cell differentiation
0.36	GO:0009440	cyanate catabolic process
0.34	GO:0016226	iron-sulfur cluster assembly
0.34	GO:0019221	cytokine-mediated signaling pathway
0.32	GO:0006508	proteolysis

0.78	GO:0004792	thiosulfate sulfurtransferase activity
0.54	GO:0008097	5S rRNA binding
0.34	GO:0004896	cytokine receptor activity
0.33	GO:0005515	protein binding
0.33	GO:0004252	serine-type endopeptidase activity

0.46	GO:0044429	mitochondrial part
0.46	GO:0019866	organelle inner membrane
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.78	EC:2.8.1.1	GO:0004792
0.78	KEGG:R01931	GO:0004792

sp|P52293|IMA1_MOUSE
Importin subunit alpha-1
Search

KPNA2

0.62	Importin subunit alpha

0.79	GO:0006606	protein import into nucleus
0.37	GO:0046015	regulation of transcription by glucose
0.35	GO:0006886	intracellular protein transport
0.34	GO:0000018	regulation of DNA recombination
0.34	GO:0075733	intracellular transport of virus
0.34	GO:0044068	modulation by symbiont of host cellular process
0.34	GO:0019048	modulation by virus of host morphology or physiology
0.33	GO:0006259	DNA metabolic process

0.82	GO:0061608	nuclear import signal receptor activity
0.69	GO:0008565	protein transporter activity
0.56	GO:0008139	nuclear localization sequence binding
0.49	GO:0042826	histone deacetylase binding
0.40	GO:0070491	repressing transcription factor binding
0.35	GO:0003723	RNA binding

0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.47	GO:0031974	membrane-enclosed lumen
0.44	GO:0012505	endomembrane system
0.43	GO:0044446	intracellular organelle part
0.41	GO:0031975	envelope
0.41	GO:0043234	protein complex
0.33	GO:0044216	other organism cell
0.33	GO:0018995	host
0.30	GO:0016020	membrane

sp|P52332|JAK1_MOUSE
Tyrosine-protein kinase JAK1
Search

JAK1

0.60	Tyrosine-protein kinase

0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.61	GO:0035556	intracellular signal transduction
0.59	GO:0038110	interleukin-2-mediated signaling pathway
0.58	GO:1903672	positive regulation of sprouting angiogenesis
0.51	GO:0046677	response to antibiotic
0.45	GO:0046777	protein autophosphorylation
0.44	GO:0045087	innate immune response
0.44	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.44	GO:0016477	cell migration
0.43	GO:0042127	regulation of cell proliferation

0.79	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.56	GO:0019903	protein phosphatase binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0005102	receptor binding

0.67	GO:0005856	cytoskeleton
0.45	GO:0005634	nucleus
0.44	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.39	GO:0005737	cytoplasm
0.35	GO:0005925	focal adhesion

0.79

GO:0004715

sp|P52430|PON1_MOUSE
Serum paraoxonase/arylesterase 1
Search

PON1

0.90	Paraoxonase

0.66	GO:0010875	positive regulation of cholesterol efflux
0.62	GO:0032411	positive regulation of transporter activity
0.62	GO:0051099	positive regulation of binding
0.61	GO:0019439	aromatic compound catabolic process
0.61	GO:0046470	phosphatidylcholine metabolic process
0.61	GO:0008203	cholesterol metabolic process
0.56	GO:0009636	response to toxic substance
0.55	GO:0046395	carboxylic acid catabolic process
0.55	GO:0046434	organophosphate catabolic process
0.54	GO:0016311	dephosphorylation

0.85	GO:0004064	arylesterase activity
0.69	GO:0004063	aryldialkylphosphatase activity
0.67	GO:0042802	identical protein binding
0.57	GO:0005543	phospholipid binding
0.56	GO:0046983	protein dimerization activity
0.54	GO:0005509	calcium ion binding

0.66	GO:0034366	spherical high-density lipoprotein particle
0.43	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.85

EC:3.1.1.2

GO:0004064

sp|P52431|DPOD1_MOUSE
DNA polymerase delta catalytic subunit
Search

POLD1

0.48	DNA polymerase delta catalytic subunit

0.67	GO:0071897	DNA biosynthetic process
0.66	GO:0006260	DNA replication
0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.56	GO:0006287	base-excision repair, gap-filling
0.49	GO:0006297	nucleotide-excision repair, DNA gap filling
0.42	GO:0055089	fatty acid homeostasis
0.41	GO:0034644	cellular response to UV
0.36	GO:0042769	DNA damage response, detection of DNA damage
0.35	GO:0006301	postreplication repair
0.35	GO:0006283	transcription-coupled nucleotide-excision repair

0.72	GO:0008408	3'-5' exonuclease activity
0.70	GO:0003887	DNA-directed DNA polymerase activity
0.64	GO:0051539	4 iron, 4 sulfur cluster binding
0.55	GO:0003677	DNA binding
0.52	GO:1901265	nucleoside phosphate binding
0.52	GO:0046872	metal ion binding
0.51	GO:0036094	small molecule binding
0.46	GO:0019899	enzyme binding
0.44	GO:0016895	exodeoxyribonuclease activity, producing 5'-phosphomonoesters
0.40	GO:0003682	chromatin binding

0.60	GO:0005634	nucleus
0.52	GO:0016235	aggresome
0.46	GO:0031974	membrane-enclosed lumen
0.45	GO:0005829	cytosol
0.44	GO:0030894	replisome
0.44	GO:0042575	DNA polymerase complex
0.38	GO:0000781	chromosome, telomeric region
0.37	GO:1990391	DNA repair complex
0.35	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.70

GO:0003887

sp|P52432|RPAC1_MOUSE
DNA-directed RNA polymerases I and III subunit RPAC1
Search

POLR1C

0.90	RNA polymerase I subunit C

0.58	GO:0006351	transcription, DNA-templated
0.45	GO:0048703	embryonic viscerocranium morphogenesis
0.44	GO:0051216	cartilage development
0.40	GO:0042254	ribosome biogenesis
0.36	GO:0040029	regulation of gene expression, epigenetic
0.35	GO:0032481	positive regulation of type I interferon production
0.34	GO:0016458	gene silencing
0.34	GO:0006325	chromatin organization
0.34	GO:0045892	negative regulation of transcription, DNA-templated
0.34	GO:0010628	positive regulation of gene expression

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.68	GO:0046983	protein dimerization activity
0.53	GO:0003677	DNA binding

0.58	GO:0005736	DNA-directed RNA polymerase I complex
0.57	GO:0005666	DNA-directed RNA polymerase III complex
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.70

EC:2.7.7.6

GO:0003899

sp|P52479|UBP10_MOUSE
Ubiquitin carboxyl-terminal hydrolase 10
Search

USP10

0.94	Ubiquitin carboxyl-terminal hydrolase 10

0.75	GO:0016579	protein deubiquitination
0.70	GO:0006511	ubiquitin-dependent protein catabolic process
0.60	GO:0030330	DNA damage response, signal transduction by p53 class mediator
0.59	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.58	GO:0071347	cellular response to interleukin-1
0.53	GO:0010506	regulation of autophagy
0.43	GO:0006914	autophagy
0.40	GO:0006281	DNA repair
0.34	GO:0071897	DNA biosynthetic process

0.75	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.58	GO:0002039	p53 binding
0.58	GO:0044325	ion channel binding
0.53	GO:0004197	cysteine-type endopeptidase activity
0.35	GO:0003723	RNA binding

0.57	GO:0005769	early endosome
0.49	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol
0.44	GO:0043234	protein complex

0.75

EC:3.4.19.12

GO:0036459

sp|P52480|KPYM_MOUSE
Pyruvate kinase PKM
Search

PKM

0.47	Pyruvate kinase PKM

0.70	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.47	GO:0012501	programmed cell death
0.46	GO:0032868	response to insulin
0.46	GO:0071375	cellular response to peptide hormone stimulus
0.39	GO:0014870	response to muscle inactivity
0.38	GO:0043403	skeletal muscle tissue regeneration
0.38	GO:0031100	animal organ regeneration

0.78	GO:0004743	pyruvate kinase activity
0.77	GO:0030955	potassium ion binding
0.64	GO:0000287	magnesium ion binding
0.60	GO:0016301	kinase activity
0.49	GO:0045296	cadherin binding
0.38	GO:0070324	thyroid hormone binding
0.37	GO:0023026	MHC class II protein complex binding
0.37	GO:0043531	ADP binding
0.36	GO:0042802	identical protein binding
0.36	GO:0005524	ATP binding

0.49	GO:0043209	myelin sheath
0.47	GO:0005929	cilium
0.45	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.41	GO:0005739	mitochondrion
0.40	GO:1902912	pyruvate kinase complex
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen

0.78

EC:2.7.1.40

GO:0004743

sp|P52482|UB2E1_MOUSE
Ubiquitin-conjugating enzyme E2 E1
Search

UBE2E1

0.89	Ubiquitin-conjugating enzyme E2 E1 isoform B

0.62	GO:0032020	ISG15-protein conjugation
0.60	GO:0070936	protein K48-linked ubiquitination
0.55	GO:0033523	histone H2B ubiquitination
0.54	GO:0010390	histone monoubiquitination
0.48	GO:0070979	protein K11-linked ubiquitination
0.47	GO:0070534	protein K63-linked ubiquitination
0.46	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.40	GO:0006974	cellular response to DNA damage stimulus
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

0.62	GO:0042296	ISG15 transferase activity
0.60	GO:0061631	ubiquitin conjugating enzyme activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.32	GO:0003723	RNA binding

0.50	GO:0000151	ubiquitin ligase complex
0.44	GO:0005634	nucleus
0.34	GO:0005829	cytosol
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P52483|UB2E3_MOUSE
Ubiquitin-conjugating enzyme E2 E3
Search

UBE2E3

0.75	Ubiquitin conjugating enzyme E2

0.63	GO:0070936	protein K48-linked ubiquitination
0.57	GO:0070979	protein K11-linked ubiquitination
0.57	GO:0070534	protein K63-linked ubiquitination
0.55	GO:0032020	ISG15-protein conjugation
0.50	GO:0033523	histone H2B ubiquitination
0.49	GO:0010390	histone monoubiquitination
0.42	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.38	GO:0006974	cellular response to DNA damage stimulus
0.36	GO:0040008	regulation of growth
0.34	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition

0.62	GO:0061631	ubiquitin conjugating enzyme activity
0.55	GO:0042296	ISG15 transferase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.46	GO:0005634	nucleus
0.46	GO:0000151	ubiquitin ligase complex
0.34	GO:0005829	cytosol
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|P52503|NDUS6_MOUSE
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
Search

NDUFS6

0.94	Mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 6

0.70	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.54	GO:0070584	mitochondrion morphogenesis
0.53	GO:0035264	multicellular organism growth
0.52	GO:0010259	multicellular organism aging
0.52	GO:0006936	muscle contraction
0.50	GO:0072358	cardiovascular system development
0.50	GO:0061458	reproductive system development
0.46	GO:0006631	fatty acid metabolic process
0.36	GO:0032981	mitochondrial respiratory chain complex I assembly

0.35	GO:0003954	NADH dehydrogenase activity
0.34	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
0.33	GO:0009055	electron transfer activity

0.76

GO:0005747

mitochondrial respiratory chain complex I

0.35

EC:1.6.99.3

GO:0003954

sp|P52592|S1PR2_MOUSE
Sphingosine 1-phosphate receptor 2
Search

S1PR2

0.94	Sphingosine 1-phosphate receptor 2

0.85	GO:0003376	sphingosine-1-phosphate signaling pathway
0.59	GO:1901552	positive regulation of endothelial cell development
0.58	GO:0090394	negative regulation of excitatory postsynaptic potential
0.58	GO:1903140	regulation of establishment of endothelial barrier
0.57	GO:0046847	filopodium assembly
0.57	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.54	GO:0031532	actin cytoskeleton reorganization
0.47	GO:0003007	heart morphogenesis
0.46	GO:0001944	vasculature development
0.46	GO:0048729	tissue morphogenesis

0.86	GO:0038036	sphingosine-1-phosphate receptor activity
0.57	GO:0001664	G-protein coupled receptor binding
0.55	GO:0005178	integrin binding
0.35	GO:0008289	lipid binding
0.35	GO:0003886	DNA (cytosine-5-)-methyltransferase activity
0.35	GO:0003682	chromatin binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0003677	DNA binding
0.32	GO:0016491	oxidoreductase activity

0.44	GO:0005886	plasma membrane
0.41	GO:0009986	cell surface
0.41	GO:0098552	side of membrane
0.41	GO:0005654	nucleoplasm
0.35	GO:0098857	membrane microdomain
0.34	GO:0005768	endosome
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:2.1.1.37

GO:0003886

sp|P52623|UCK1_MOUSE
Uridine-cytidine kinase 1
Search

UCK1

0.85	Uridine-cytidine kinase

0.69	GO:0044211	CTP salvage
0.67	GO:0044206	UMP salvage
0.57	GO:0016310	phosphorylation
0.54	GO:0006238	CMP salvage
0.45	GO:0006206	pyrimidine nucleobase metabolic process
0.34	GO:0072583	clathrin-dependent endocytosis

0.78	GO:0019206	nucleoside kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding

0.44	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|P52624|UPP1_MOUSE
Uridine phosphorylase 1
Search

UPP1

0.59	Uridine phosphorylase

0.76	GO:0044206	UMP salvage
0.74	GO:0009166	nucleotide catabolic process
0.55	GO:0046108	uridine metabolic process
0.51	GO:0046135	pyrimidine nucleoside catabolic process
0.50	GO:0042454	ribonucleoside catabolic process
0.40	GO:0042149	cellular response to glucose starvation

0.82	GO:0004850	uridine phosphorylase activity
0.35	GO:0042802	identical protein binding

0.48	GO:0005737	cytoplasm
0.48	GO:0045098	type III intermediate filament
0.46	GO:0005654	nucleoplasm

0.82

EC:2.4.2.3

GO:0004850

sp|P52633|STAT6_MOUSE
Signal transducer and transcription activator 6
Search

STAT6

0.69	Signal transducer and activator of transcription

0.66	GO:0035771	interleukin-4-mediated signaling pathway
0.66	GO:0002296	T-helper 1 cell lineage commitment
0.65	GO:0048295	positive regulation of isotype switching to IgE isotypes
0.63	GO:0002829	negative regulation of type 2 immune response
0.63	GO:0033598	mammary gland epithelial cell proliferation
0.62	GO:0060443	mammary gland morphogenesis
0.58	GO:0042127	regulation of cell proliferation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0006366	transcription by RNA polymerase II

0.64	GO:0004871	signal transducer activity
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0019903	protein phosphatase binding
0.58	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0042802	identical protein binding
0.36	GO:0035259	glucocorticoid receptor binding
0.34	GO:0046983	protein dimerization activity
0.33	GO:0004713	protein tyrosine kinase activity

0.61	GO:0005634	nucleus
0.53	GO:0000785	chromatin
0.53	GO:0005829	cytosol
0.52	GO:0070013	intracellular organelle lumen
0.51	GO:0012505	endomembrane system
0.48	GO:0031967	organelle envelope
0.47	GO:0031090	organelle membrane
0.39	GO:0098857	membrane microdomain
0.30	GO:0016021	integral component of membrane

0.33

GO:0004713

sp|P52651|RHOX5_MOUSE
Homeobox protein Rhox5
Search

RHOX5

0.37	Homeodomain (Fragment)

0.55

GO:0003677

DNA binding

0.61

GO:0005634

nucleus

sp|P52734|FGD1_MOUSE
FYVE, RhoGEF and PH domain-containing protein 1
Search

FGD1

0.93	LOW QUALITY PROTEIN: FYVE, RhoGEF and PH domain-containing protein 1

0.77	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.65	GO:0046847	filopodium assembly
0.55	GO:0030036	actin cytoskeleton organization
0.53	GO:0008360	regulation of cell shape
0.36	GO:0043065	positive regulation of apoptotic process
0.36	GO:0009887	animal organ morphogenesis
0.35	GO:0007186	G-protein coupled receptor signaling pathway

0.77	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.53	GO:0046872	metal ion binding

0.61	GO:0001726	ruffle
0.60	GO:0030027	lamellipodium
0.54	GO:0005794	Golgi apparatus
0.37	GO:0005856	cytoskeleton
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P52760|UK114_MOUSE
Ribonuclease UK114
Search

0.78	Heat-responsive protein 12

0.65

GO:1901565

organonitrogen compound catabolic process

0.73

GO:0019239

deaminase activity

0.61	GO:0005634	nucleus
0.61	GO:0005739	mitochondrion

sp|P52785|GUC2E_MOUSE
Guanylyl cyclase GC-E
Search

GUCY2D

0.57	Guanylate cyclase

0.82	GO:0006182	cGMP biosynthetic process
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.48	GO:0007601	visual perception
0.46	GO:0050962	detection of light stimulus involved in sensory perception
0.45	GO:0035845	photoreceptor cell outer segment organization
0.44	GO:0009584	detection of visible light

0.82	GO:0004383	guanylate cyclase activity
0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0004016	adenylate cyclase activity

0.49	GO:0008074	guanylate cyclase complex, soluble
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.82

EC:4.6.1.2

GO:0004383

sp|P52787|IF_MOUSE
Gastric intrinsic factor
Search

GIF

0.97	Gastric intrinsic factor

0.78	GO:0015889	cobalamin transport
0.45	GO:0006824	cobalt ion transport
0.39	GO:0009235	cobalamin metabolic process
0.39	GO:0043043	peptide biosynthetic process
0.37	GO:0044267	cellular protein metabolic process
0.37	GO:0010467	gene expression
0.37	GO:0009059	macromolecule biosynthetic process
0.35	GO:0006886	intracellular protein transport
0.35	GO:0016192	vesicle-mediated transport

0.75	GO:0031419	cobalamin binding
0.40	GO:0003735	structural constituent of ribosome
0.36	GO:0019843	rRNA binding

0.70	GO:0005902	microvillus
0.68	GO:0016324	apical plasma membrane
0.63	GO:0005768	endosome
0.62	GO:0005615	extracellular space
0.39	GO:0005840	ribosome
0.39	GO:0043202	lysosomal lumen
0.36	GO:0030117	membrane coat
0.30	GO:0031224	intrinsic component of membrane

sp|P52792|HXK4_MOUSE
Glucokinase
Search

GCK

0.58	Phosphotransferase

0.81	GO:0001678	cellular glucose homeostasis
0.73	GO:0046835	carbohydrate phosphorylation
0.70	GO:0006757	ATP generation from ADP
0.68	GO:0006090	pyruvate metabolic process
0.67	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.57	GO:0051594	detection of glucose
0.57	GO:0045725	positive regulation of glycogen biosynthetic process
0.57	GO:0050796	regulation of insulin secretion
0.56	GO:0090277	positive regulation of peptide hormone secretion

0.82	GO:0005536	glucose binding
0.78	GO:0004396	hexokinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005509	calcium ion binding

0.49	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.43	GO:0005739	mitochondrion

0.78

EC:2.7.1.1

GO:0004396

sp|P52793|EFNA1_MOUSE
Ephrin-A1
Search

0.83	GO:0048013	ephrin receptor signaling pathway
0.61	GO:0061002	negative regulation of dendritic spine morphogenesis
0.61	GO:1905247	positive regulation of aspartic-type peptidase activity
0.61	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation
0.61	GO:1902959	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
0.60	GO:1902004	positive regulation of amyloid-beta formation
0.60	GO:0003180	aortic valve morphogenesis
0.60	GO:0014028	notochord formation
0.60	GO:0070244	negative regulation of thymocyte apoptotic process
0.60	GO:0003183	mitral valve morphogenesis

0.85

GO:0046875

ephrin receptor binding

0.57	GO:0046658	anchored component of plasma membrane
0.38	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.34	GO:0005887	integral component of plasma membrane

sp|P52795|EFNB1_MOUSE
Ephrin-B1
Search

0.74	GO:0048013	ephrin receptor signaling pathway
0.61	GO:0031295	T cell costimulation
0.58	GO:0001667	ameboidal-type cell migration
0.56	GO:0008284	positive regulation of cell proliferation
0.56	GO:0048699	generation of neurons
0.55	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.55	GO:0009888	tissue development
0.55	GO:0000904	cell morphogenesis involved in differentiation
0.54	GO:0048513	animal organ development
0.54	GO:0120036	plasma membrane bounded cell projection organization

0.76	GO:0046875	ephrin receptor binding
0.34	GO:0016301	kinase activity

0.52	GO:0045121	membrane raft
0.45	GO:0005886	plasma membrane
0.44	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.36	GO:0045202	synapse
0.34	GO:0005925	focal adhesion
0.30	GO:0016021	integral component of membrane

sp|P52800|EFNB2_MOUSE
Ephrin-B2
Search

0.79	GO:0048013	ephrin receptor signaling pathway
0.59	GO:0031295	T cell costimulation
0.58	GO:0002042	cell migration involved in sprouting angiogenesis
0.57	GO:1903849	positive regulation of aorta morphogenesis
0.56	GO:1901216	positive regulation of neuron death
0.56	GO:0048699	generation of neurons
0.56	GO:0008284	positive regulation of cell proliferation
0.56	GO:0048845	venous blood vessel morphogenesis
0.55	GO:0010839	negative regulation of keratinocyte proliferation
0.55	GO:0072178	nephric duct morphogenesis

0.81	GO:0046875	ephrin receptor binding
0.35	GO:0104005	hijacked molecular function
0.33	GO:0016301	kinase activity

0.44	GO:0005886	plasma membrane
0.43	GO:0045121	membrane raft
0.38	GO:0005634	nucleus
0.36	GO:0005925	focal adhesion
0.35	GO:0005737	cytoplasm
0.33	GO:0070062	extracellular exosome
0.33	GO:0045202	synapse
0.30	GO:0016021	integral component of membrane

sp|P52801|EFNA2_MOUSE
Ephrin-A2
Search

0.92	Putative ephrin ligand for eph receptor tyrosine kinase

0.83	GO:0048013	ephrin receptor signaling pathway
0.54	GO:0030316	osteoclast differentiation
0.54	GO:0046849	bone remodeling
0.52	GO:0007411	axon guidance
0.47	GO:0071372	cellular response to follicle-stimulating hormone stimulus
0.47	GO:0048672	positive regulation of collateral sprouting
0.47	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading
0.47	GO:0048668	collateral sprouting
0.47	GO:1904321	response to forskolin
0.47	GO:0090109	regulation of cell-substrate junction assembly

0.85	GO:0046875	ephrin receptor binding
0.48	GO:0005169	neurotrophin TRKB receptor binding
0.48	GO:0045499	chemorepellent activity
0.36	GO:0016301	kinase activity
0.35	GO:0005170	neurotrophin TRKC receptor binding
0.35	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.35	GO:0005168	neurotrophin TRKA receptor binding
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0003723	RNA binding
0.33	GO:0140096	catalytic activity, acting on a protein

0.47	GO:0031225	anchored component of membrane
0.47	GO:0031233	intrinsic component of external side of plasma membrane
0.45	GO:0005604	basement membrane
0.44	GO:0005912	adherens junction
0.40	GO:0043204	perikaryon
0.40	GO:0031594	neuromuscular junction
0.37	GO:0005901	caveola
0.30	GO:0016021	integral component of membrane

0.33

GO:0016773

sp|P52825|CPT2_MOUSE
Carnitine O-palmitoyltransferase 2, mitochondrial
Search

CPT2

0.90	Mitochondrial carnitine palmitoyltransferase II

0.40	GO:0006635	fatty acid beta-oxidation
0.37	GO:0015909	long-chain fatty acid transport
0.36	GO:1902001	fatty acid transmembrane transport
0.35	GO:0032365	intracellular lipid transport
0.35	GO:1990542	mitochondrial transmembrane transport
0.35	GO:0019216	regulation of lipid metabolic process

0.62

GO:0016746

transferase activity, transferring acyl groups

0.53	GO:0005730	nucleolus
0.52	GO:0005654	nucleoplasm
0.48	GO:0005739	mitochondrion
0.38	GO:0019866	organelle inner membrane

0.62

GO:0016746

sp|P52840|ST1A1_MOUSE
Sulfotransferase 1A1
Search

0.56	Sulfotransferase

0.46	GO:0051923	sulfation
0.44	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.44	GO:0006068	ethanol catabolic process
0.43	GO:0006584	catecholamine metabolic process
0.42	GO:0008202	steroid metabolic process
0.40	GO:0006805	xenobiotic metabolic process
0.39	GO:0009812	flavonoid metabolic process
0.38	GO:0000103	sulfate assimilation
0.38	GO:0042445	hormone metabolic process
0.36	GO:0018960	4-nitrophenol metabolic process

0.77	GO:0008146	sulfotransferase activity
0.36	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding
0.35	GO:0005515	protein binding
0.35	GO:0043199	sulfate binding

0.38

GO:0005829

cytosol

0.77

GO:0008146

sp|P52843|ST2A1_MOUSE
Bile salt sulfotransferase 1
Search

0.54	Bile salt sulfotransferase

0.50	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.50	GO:0008202	steroid metabolic process
0.49	GO:0051923	sulfation
0.48	GO:0006068	ethanol catabolic process
0.41	GO:0071305	cellular response to vitamin D
0.41	GO:0017085	response to insecticide
0.40	GO:0014823	response to activity
0.39	GO:0007568	aging
0.39	GO:0045606	positive regulation of epidermal cell differentiation
0.37	GO:0008285	negative regulation of cell proliferation

0.78	GO:0008146	sulfotransferase activity
0.41	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding
0.39	GO:1990239	steroid hormone binding
0.38	GO:0015485	cholesterol binding
0.35	GO:0008144	drug binding
0.34	GO:0003676	nucleic acid binding
0.33	GO:0005515	protein binding
0.32	GO:0003735	structural constituent of ribosome
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0005829	cytosol
0.35	GO:0043227	membrane-bounded organelle
0.34	GO:0043229	intracellular organelle
0.33	GO:0043230	extracellular organelle
0.33	GO:0012505	endomembrane system
0.33	GO:0005615	extracellular space
0.32	GO:0008305	integrin complex
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043228	non-membrane-bounded organelle

0.78

GO:0008146

sp|P52850|NDST2_MOUSE
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2
Search

NDST2

0.97	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2

0.51	GO:0015012	heparan sulfate proteoglycan biosynthetic process
0.50	GO:0048702	embryonic neurocranium morphogenesis
0.49	GO:0007585	respiratory gaseous exchange
0.49	GO:0045880	positive regulation of smoothened signaling pathway
0.49	GO:0060976	coronary vasculature development
0.49	GO:0048703	embryonic viscerocranium morphogenesis
0.48	GO:0035904	aorta development
0.48	GO:0030901	midbrain development
0.48	GO:0003279	cardiac septum development
0.47	GO:0008543	fibroblast growth factor receptor signaling pathway

0.85	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity
0.51	GO:0016787	hydrolase activity
0.51	GO:0042328	heparan sulfate N-acetylglucosaminyltransferase activity
0.34	GO:0005515	protein binding

0.39	GO:0005794	Golgi apparatus
0.38	GO:0098588	bounding membrane of organelle
0.38	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.85

EC:2.8.2.8

GO:0015016

sp|P52875|TM165_MOUSE
Transmembrane protein 165
Search

TMEM165

0.50	Transmembrane protein 165

0.60	GO:0032472	Golgi calcium ion transport
0.59	GO:0035751	regulation of lysosomal lumen pH
0.57	GO:0006487	protein N-linked glycosylation
0.54	GO:0006874	cellular calcium ion homeostasis
0.44	GO:0060536	cartilage morphogenesis
0.44	GO:0048703	embryonic viscerocranium morphogenesis
0.43	GO:0002062	chondrocyte differentiation
0.43	GO:0001649	osteoblast differentiation
0.33	GO:0006629	lipid metabolic process
0.32	GO:0055114	oxidation-reduction process

0.33

GO:0016627

oxidoreductase activity, acting on the CH-CH group of donors

0.57	GO:0032588	trans-Golgi network membrane
0.55	GO:0005765	lysosomal membrane
0.53	GO:0010008	endosome membrane
0.38	GO:0005770	late endosome
0.38	GO:0005769	early endosome
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:1.3

GO:0016627

sp|P52912|TIA1_MOUSE
Nucleolysin TIA-1
Search

TIA1

0.83	Cytotoxic granule-associated RNA binding protein 1, like

0.57	GO:1903608	protein localization to cytoplasmic stress granule
0.55	GO:0042036	negative regulation of cytokine biosynthetic process
0.53	GO:0048024	regulation of mRNA splicing, via spliceosome
0.50	GO:0017148	negative regulation of translation
0.40	GO:1904037	positive regulation of epithelial cell apoptotic process
0.38	GO:0017145	stem cell division
0.37	GO:0007281	germ cell development
0.37	GO:0008284	positive regulation of cell proliferation
0.36	GO:0006915	apoptotic process
0.35	GO:0008543	fibroblast growth factor receptor signaling pathway

0.59	GO:0003723	RNA binding
0.37	GO:0003677	DNA binding
0.34	GO:0005515	protein binding

0.57	GO:0097165	nuclear stress granule
0.53	GO:0010494	cytoplasmic stress granule
0.48	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P52927|HMGA2_MOUSE
High mobility group protein HMGI-C
Search

HMGA2

0.96	High mobility group protein HMGI-C

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0090402	oncogene-induced cell senescence
0.53	GO:0035986	senescence-associated heterochromatin focus assembly
0.52	GO:2000774	positive regulation of cellular senescence
0.49	GO:0031052	chromosome breakage
0.49	GO:0035978	histone H2A-S139 phosphorylation
0.49	GO:0003131	mesodermal-endodermal cell signaling
0.48	GO:2000685	positive regulation of cellular response to X-ray

0.55	GO:0003677	DNA binding
0.49	GO:0035501	MH1 domain binding
0.48	GO:0051575	5'-deoxyribose-5-phosphate lyase activity
0.48	GO:0035500	MH2 domain binding
0.47	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity
0.47	GO:0070742	C2H2 zinc finger domain binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0004677	DNA-dependent protein kinase activity
0.46	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0031491	nucleosome binding

0.71	GO:0000785	chromatin
0.61	GO:0005634	nucleus
0.47	GO:0071141	SMAD protein complex
0.42	GO:0032993	protein-DNA complex
0.41	GO:0070013	intracellular organelle lumen
0.36	GO:0005667	transcription factor complex
0.34	GO:0005925	focal adhesion
0.33	GO:0005829	cytosol

0.47	EC:4.2.99.18	GO:0003906
0.32	KEGG:R03876	GO:0004842

sp|P52946|PDX1_MOUSE
Pancreas/duodenum homeobox protein 1
Search

PDX1

0.97	Pancreatic and duodenal homeobox

0.60	GO:0031018	endocrine pancreas development
0.59	GO:2000675	negative regulation of type B pancreatic cell apoptotic process
0.59	GO:0007263	nitric oxide mediated signal transduction
0.58	GO:0001889	liver development
0.58	GO:0035883	enteroendocrine cell differentiation
0.58	GO:0030073	insulin secretion
0.57	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.57	GO:0031017	exocrine pancreas development
0.57	GO:0048565	digestive tract development
0.57	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus

0.64	GO:0043565	sequence-specific DNA binding
0.57	GO:0003700	DNA binding transcription factor activity
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003682	chromatin binding
0.51	GO:0003690	double-stranded DNA binding
0.41	GO:0008134	transcription factor binding
0.37	GO:0032403	protein complex binding
0.36	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.50	GO:0070013	intracellular organelle lumen
0.45	GO:0044446	intracellular organelle part
0.40	GO:0005829	cytosol
0.38	GO:0012505	endomembrane system
0.37	GO:0031090	organelle membrane
0.37	GO:0031975	envelope
0.35	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

sp|P52950|DBX1_MOUSE
Homeobox protein DBX1
Search

DBX1

0.97	Developing brain homeobox 1

0.59	GO:0021521	ventral spinal cord interneuron specification
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.37	GO:0007411	axon guidance

0.63	GO:0043565	sequence-specific DNA binding
0.33	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33

EC:3.5.4.4

GO:0004000

sp|P52955|LBX1_MOUSE
Transcription factor LBX1
Search

LBX1

0.97	Ladybird homeobox 1 transcription factor

0.61	GO:0021920	regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification
0.59	GO:0048664	neuron fate determination
0.57	GO:0021522	spinal cord motor neuron differentiation
0.56	GO:0001947	heart looping
0.55	GO:0045665	negative regulation of neuron differentiation
0.53	GO:0008285	negative regulation of cell proliferation
0.46	GO:0061061	muscle structure development
0.41	GO:0048468	cell development
0.38	GO:0051450	myoblast proliferation
0.36	GO:0060026	convergent extension

0.64	GO:0043565	sequence-specific DNA binding
0.45	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.52	GO:0005667	transcription factor complex
0.30	GO:0016021	integral component of membrane

sp|P52963|E41LA_MOUSE
Band 4.1-like protein 4A
Search

EPB41L4A

0.97	Erythrocyte membrane protein band 4.1 like 4A

0.49

GO:0031032

actomyosin structure organization

0.57	GO:0008092	cytoskeletal protein binding
0.47	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0005516	calmodulin binding

0.68	GO:0005856	cytoskeleton
0.33	GO:0005737	cytoplasm

sp|P53026|RL10A_MOUSE
60S ribosomal protein L10a
Search

RPL10A

0.55	Ribosomal protein (Fragment)

0.58	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.44	GO:0042273	ribosomal large subunit biogenesis
0.41	GO:0016072	rRNA metabolic process
0.35	GO:0045471	response to ethanol

0.61	GO:0003735	structural constituent of ribosome
0.57	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.67	GO:0015934	large ribosomal subunit
0.49	GO:0022626	cytosolic ribosome
0.49	GO:0042788	polysomal ribosome
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

sp|P53347|ONCM_MOUSE
Oncostatin-M
Search

OSM

0.85	Oncostatin-M

0.76	GO:0010469	regulation of receptor activity
0.75	GO:0038165	oncostatin-M-mediated signaling pathway
0.74	GO:0006955	immune response
0.71	GO:0046888	negative regulation of hormone secretion
0.71	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.70	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.66	GO:0043410	positive regulation of MAPK cascade
0.65	GO:0008284	positive regulation of cell proliferation
0.63	GO:0045944	positive regulation of transcription by RNA polymerase II
0.57	GO:0008285	negative regulation of cell proliferation

0.81	GO:0005125	cytokine activity
0.78	GO:0005147	oncostatin-M receptor binding
0.65	GO:0008083	growth factor activity

0.66	GO:0005576	extracellular region
0.36	GO:0005622	intracellular

sp|P53349|M3K1_MOUSE
Mitogen-activated protein kinase kinase kinase 1
Search

MAP3K1

0.95	Mitogen-activated protein kinase kinase kinase 1

0.62	GO:0006468	protein phosphorylation
0.59	GO:0071260	cellular response to mechanical stimulus
0.47	GO:0031098	stress-activated protein kinase signaling cascade
0.47	GO:0032147	activation of protein kinase activity
0.45	GO:0007346	regulation of mitotic cell cycle
0.44	GO:0042981	regulation of apoptotic process
0.41	GO:0043406	positive regulation of MAP kinase activity
0.40	GO:0061029	eyelid development in camera-type eye
0.39	GO:0003382	epithelial cell morphogenesis
0.39	GO:0008637	apoptotic mitochondrial changes

0.62	GO:0004672	protein kinase activity
0.61	GO:0008270	zinc ion binding
0.56	GO:0019901	protein kinase binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0005057	signal transducer activity, downstream of receptor
0.37	GO:0046625	sphingolipid binding
0.37	GO:0008092	cytoskeletal protein binding

0.39	GO:0031941	filamentous actin
0.36	GO:0005737	cytoplasm
0.35	GO:0030054	cell junction
0.30	GO:0016020	membrane

0.35

GO:0004842

sp|P53351|PLK2_MOUSE
Serine/threonine-protein kinase PLK2
Search

PLK2

0.89	Serine/threonine-protein kinase PLK2

0.63	GO:0006468	protein phosphorylation
0.50	GO:0032486	Rap protein signal transduction
0.50	GO:0060292	long term synaptic depression
0.49	GO:0046599	regulation of centriole replication
0.49	GO:0060291	long-term synaptic potentiation
0.48	GO:0007613	memory
0.48	GO:0016525	negative regulation of angiogenesis
0.48	GO:0061000	negative regulation of dendritic spine development
0.48	GO:0000082	G1/S transition of mitotic cell cycle
0.48	GO:0007052	mitotic spindle organization

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0043008	ATP-dependent protein binding
0.43	GO:0032403	protein complex binding
0.38	GO:0004871	signal transducer activity

0.47	GO:0005814	centriole
0.47	GO:0030425	dendrite
0.46	GO:0005813	centrosome
0.44	GO:0000785	chromatin
0.37	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P53368|8ODP_MOUSE
7,8-dihydro-8-oxoguanine triphosphatase
Search

NUDT1

0.65	Nudix (Nucleoside diphosphate linked moiety X)-type motif 1

0.65	GO:0006281	DNA repair
0.57	GO:0046061	dATP catabolic process
0.55	GO:0006203	dGTP catabolic process
0.54	GO:0042262	DNA protection
0.39	GO:0008584	male gonad development
0.39	GO:0046686	response to cadmium ion
0.39	GO:0007568	aging
0.36	GO:0034656	nucleobase-containing small molecule catabolic process
0.34	GO:0006979	response to oxidative stress

0.82	GO:0008413	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
0.58	GO:0036219	GTP diphosphatase activity
0.58	GO:0035539	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity
0.55	GO:0047693	ATP diphosphatase activity
0.52	GO:0030515	snoRNA binding
0.46	GO:0003924	GTPase activity
0.41	GO:0044713	2-hydroxy-adenosine triphosphate pyrophosphatase activity
0.41	GO:0044714	2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity
0.39	GO:0050072	m7G(5')pppN diphosphatase activity
0.34	GO:0046872	metal ion binding

0.50	GO:0005759	mitochondrial matrix
0.47	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.39	GO:0001669	acrosomal vesicle
0.37	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.36	GO:0031967	organelle envelope
0.35	GO:0031090	organelle membrane
0.35	GO:0005886	plasma membrane

0.82	EC:3.6.1	GO:0008413
0.58	KEGG:R00426	GO:0036219

sp|P53395|ODB2_MOUSE
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial
Search

DBT

0.44	Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

0.51	GO:0009083	branched-chain amino acid catabolic process
0.36	GO:0034641	cellular nitrogen compound metabolic process

0.76	GO:0043754	dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity
0.66	GO:0031625	ubiquitin protein ligase binding

0.69	GO:0042645	mitochondrial nucleoid
0.54	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex

0.76

EC:2.3.1.168

GO:0043754

sp|P53564|CUX1_MOUSE
Homeobox protein cut-like 1
Search

CUX1

0.64	Homeobox protein cut-like

0.55	GO:0006891	intra-Golgi vesicle-mediated transport
0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.52	GO:0006351	transcription, DNA-templated
0.41	GO:1902679	negative regulation of RNA biosynthetic process
0.40	GO:0007275	multicellular organism development
0.30	GO:0031344	regulation of cell projection organization
0.30	GO:0030154	cell differentiation
0.30	GO:0010769	regulation of cell morphogenesis involved in differentiation

0.58	GO:0043565	sequence-specific DNA binding
0.42	GO:0001012	RNA polymerase II regulatory region DNA binding
0.41	GO:0003690	double-stranded DNA binding
0.30	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.30	GO:0003682	chromatin binding

0.57	GO:0005634	nucleus
0.56	GO:0030173	integral component of Golgi membrane
0.44	GO:0031974	membrane-enclosed lumen
0.30	GO:0043005	neuron projection

sp|P53566|CEBPA_MOUSE
CCAAT/enhancer-binding protein alpha
Search

CEBPA

0.81	CCAAT/enhancer-binding protein epsilon

0.62	GO:0030851	granulocyte differentiation
0.60	GO:0030225	macrophage differentiation
0.59	GO:0001889	liver development
0.58	GO:0045600	positive regulation of fat cell differentiation
0.57	GO:0045669	positive regulation of osteoblast differentiation
0.57	GO:0045444	fat cell differentiation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0071285	cellular response to lithium ion

0.61	GO:0003700	DNA binding transcription factor activity
0.57	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.55	GO:0000987	proximal promoter sequence-specific DNA binding
0.53	GO:0019900	kinase binding
0.53	GO:0042803	protein homodimerization activity
0.51	GO:0003713	transcription coactivator activity
0.48	GO:0008134	transcription factor binding
0.45	GO:0042826	histone deacetylase binding
0.44	GO:0035035	histone acetyltransferase binding
0.44	GO:0001046	core promoter sequence-specific DNA binding

0.52	GO:0005654	nucleoplasm
0.50	GO:0090575	RNA polymerase II transcription factor complex
0.45	GO:0016363	nuclear matrix
0.42	GO:0000779	condensed chromosome, centromeric region
0.41	GO:0000790	nuclear chromatin
0.40	GO:0005730	nucleolus
0.35	GO:0005737	cytoplasm
0.32	GO:0005886	plasma membrane

sp|P53568|CEBPG_MOUSE
CCAAT/enhancer-binding protein gamma
Search

CEBPG

0.97	CCAAT/enhancer-binding protein gamma

0.60	GO:0043353	enucleate erythrocyte differentiation
0.60	GO:0045078	positive regulation of interferon-gamma biosynthetic process
0.59	GO:0042267	natural killer cell mediated cytotoxicity
0.57	GO:0045739	positive regulation of DNA repair
0.57	GO:0030183	B cell differentiation
0.56	GO:0043433	negative regulation of DNA binding transcription factor activity
0.52	GO:0006366	transcription by RNA polymerase II
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:0016071	mRNA metabolic process
0.41	GO:0001889	liver development

0.58	GO:0003700	DNA binding transcription factor activity
0.55	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0042803	protein homodimerization activity
0.52	GO:0046982	protein heterodimerization activity
0.51	GO:0008134	transcription factor binding
0.40	GO:0044374	sequence-specific DNA binding, bending

0.49	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P53569|CEBPZ_MOUSE
CCAAT/enhancer-binding protein zeta
Search

CEBPZ

0.94	CCAAT/enhancer-binding protein zeta

0.74	GO:0006366	transcription by RNA polymerase II
0.73	GO:0045944	positive regulation of transcription by RNA polymerase II

0.80	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.78	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0003723	RNA binding

0.50	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P53612|PGTB2_MOUSE
Geranylgeranyl transferase type-2 subunit beta
Search

RABGGTB

0.83	Rab geranylgeranyltransferase beta subunit

0.83	GO:0018344	protein geranylgeranylation
0.35	GO:0043687	post-translational protein modification
0.34	GO:0007601	visual perception
0.34	GO:0042981	regulation of apoptotic process
0.34	GO:0006461	protein complex assembly
0.33	GO:0006298	mismatch repair
0.33	GO:0055114	oxidation-reduction process

0.85	GO:0004663	Rab geranylgeranyltransferase activity
0.39	GO:0017137	Rab GTPase binding
0.36	GO:0008270	zinc ion binding
0.35	GO:0003995	acyl-CoA dehydrogenase activity
0.35	GO:0019840	isoprenoid binding
0.34	GO:0050660	flavin adenine dinucleotide binding
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0030983	mismatched DNA binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.48	GO:0005968	Rab-protein geranylgeranyltransferase complex
0.33	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.85

EC:2.5.1.60

GO:0004663

sp|P53657|KPYR_MOUSE
Pyruvate kinase PKLR
Search

PKLR

0.47	Pyruvate kinase PKLR

0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.46	GO:0032869	cellular response to insulin stimulus
0.39	GO:0071872	cellular response to epinephrine stimulus
0.39	GO:0010226	response to lithium ion
0.39	GO:0051591	response to cAMP
0.38	GO:0033198	response to ATP
0.38	GO:0009749	response to glucose

0.78	GO:0004743	pyruvate kinase activity
0.77	GO:0030955	potassium ion binding
0.64	GO:0000287	magnesium ion binding
0.60	GO:0016301	kinase activity
0.38	GO:0045296	cadherin binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005248	voltage-gated sodium channel activity
0.34	GO:0005249	voltage-gated potassium channel activity

0.39	GO:0005829	cytosol
0.39	GO:0043209	myelin sheath
0.38	GO:0005929	cilium
0.36	GO:0070062	extracellular exosome
0.35	GO:0005634	nucleus
0.35	GO:0005739	mitochondrion
0.33	GO:0005887	integral component of plasma membrane

0.78

EC:2.7.1.40

GO:0004743

sp|P53668|LIMK1_MOUSE
LIM domain kinase 1
Search

LIMK1

0.92	LIM domain kinase 1

0.62	GO:0006468	protein phosphorylation
0.60	GO:0051496	positive regulation of stress fiber assembly
0.59	GO:0051444	negative regulation of ubiquitin-protein transferase activity
0.57	GO:0045773	positive regulation of axon extension
0.45	GO:0030036	actin cytoskeleton organization
0.44	GO:0001878	response to yeast
0.42	GO:0035556	intracellular signal transduction
0.36	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0031072	heat shock protein binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.51	GO:0046982	protein heterodimerization activity
0.43	GO:0004871	signal transducer activity
0.35	GO:0005201	extracellular matrix structural constituent

0.55	GO:0030027	lamellipodium
0.55	GO:0043005	neuron projection
0.55	GO:0016607	nuclear speck
0.55	GO:0005925	focal adhesion
0.49	GO:0005829	cytosol
0.45	GO:0005794	Golgi apparatus
0.37	GO:0030427	site of polarized growth
0.36	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005578	proteinaceous extracellular matrix

sp|P53690|MMP14_MOUSE
Matrix metalloproteinase-14
Search

MMP14

0.72	Membrane-type matrix metalloproteinase

0.81	GO:0030307	positive regulation of cell growth
0.78	GO:0030335	positive regulation of cell migration
0.61	GO:0006508	proteolysis
0.60	GO:0045579	positive regulation of B cell differentiation
0.59	GO:0010831	positive regulation of myotube differentiation
0.58	GO:0048701	embryonic cranial skeleton morphogenesis
0.58	GO:0045746	negative regulation of Notch signaling pathway
0.58	GO:0035988	chondrocyte proliferation
0.58	GO:0097094	craniofacial suture morphogenesis
0.57	GO:0007369	gastrulation

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.52	GO:0070006	metalloaminopeptidase activity
0.39	GO:0005178	integrin binding
0.39	GO:0016504	peptidase activator activity
0.34	GO:0004252	serine-type endopeptidase activity

0.74	GO:0031012	extracellular matrix
0.59	GO:0044352	pinosome
0.53	GO:0045111	intermediate filament cytoskeleton
0.50	GO:0005615	extracellular space
0.48	GO:0005829	cytosol
0.45	GO:0005886	plasma membrane
0.45	GO:0005634	nucleus
0.44	GO:0042470	melanosome
0.37	GO:0005925	focal adhesion
0.36	GO:0005796	Golgi lumen

0.70

GO:0004222

sp|P53702|CCHL_MOUSE
Cytochrome c-type heme lyase
Search

HCCS

0.65	Cytochrome c-type heme lyase

0.48	GO:0018063	cytochrome c-heme linkage
0.34	GO:0009887	animal organ morphogenesis
0.32	GO:0055114	oxidation-reduction process

0.85	GO:0004408	holocytochrome-c synthase activity
0.54	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.85

EC:4.4.1.17

GO:0004408

sp|P53762|ARNT_MOUSE
Aryl hydrocarbon receptor nuclear translocator
Search

ARNT

0.90	Aryl hydrocarbon receptor nuclear translocator

0.60	GO:0033235	positive regulation of protein sumoylation
0.60	GO:0046886	positive regulation of hormone biosynthetic process
0.59	GO:0010575	positive regulation of vascular endothelial growth factor production
0.59	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0001666	response to hypoxia
0.56	GO:0001892	embryonic placenta development
0.55	GO:0045893	positive regulation of transcription, DNA-templated
0.55	GO:0030522	intracellular receptor signaling pathway
0.51	GO:0030154	cell differentiation

0.68	GO:0046983	protein dimerization activity
0.67	GO:0017162	aryl hydrocarbon receptor binding
0.61	GO:0003700	DNA binding transcription factor activity
0.59	GO:0004874	aryl hydrocarbon receptor activity
0.58	GO:0044212	transcription regulatory region DNA binding
0.54	GO:0003713	transcription coactivator activity
0.51	GO:0043565	sequence-specific DNA binding
0.45	GO:0003690	double-stranded DNA binding
0.35	GO:0008234	cysteine-type peptidase activity
0.35	GO:0070491	repressing transcription factor binding

0.74	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.52	GO:0034751	aryl hydrocarbon receptor complex
0.49	GO:0005737	cytoplasm
0.48	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.35

GO:0008234

sp|P53776|LHX4_MOUSE
LIM/homeobox protein Lhx4
Search

LHX4

0.93	LIM homeobox 4

0.76	GO:0021526	medial motor column neuron differentiation
0.70	GO:0008045	motor neuron axon guidance
0.64	GO:0001890	placenta development
0.64	GO:0043066	negative regulation of apoptotic process
0.61	GO:0045944	positive regulation of transcription by RNA polymerase II
0.61	GO:0009887	animal organ morphogenesis
0.58	GO:0021521	ventral spinal cord interneuron specification
0.47	GO:0021527	spinal cord association neuron differentiation
0.47	GO:0021520	spinal cord motor neuron cell fate specification
0.46	GO:0021983	pituitary gland development

0.65	GO:0043565	sequence-specific DNA binding
0.54	GO:0046872	metal ion binding
0.45	GO:0001085	RNA polymerase II transcription factor binding
0.45	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.43	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.43	GO:0001012	RNA polymerase II regulatory region DNA binding
0.42	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.43	GO:0005667	transcription factor complex

sp|P53783|SOX1_MOUSE
Transcription factor SOX-1
Search

SOX1

0.96	Transcription factor SOX-1

0.65	GO:0007399	nervous system development
0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0060573	cell fate specification involved in pattern specification
0.52	GO:0010468	regulation of gene expression
0.52	GO:0002089	lens morphogenesis in camera-type eye
0.50	GO:1990830	cellular response to leukemia inhibitory factor
0.50	GO:0009953	dorsal/ventral pattern formation
0.49	GO:0060322	head development
0.48	GO:0016477	cell migration

0.54	GO:0003677	DNA binding
0.49	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0005515	protein binding
0.35	GO:0035198	miRNA binding

0.61	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex
0.33	GO:0005829	cytosol
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P53784|SOX3_MOUSE
Transcription factor SOX-3
Search

SOX3

0.83	Transcription factor SOX-3

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0007530	sex determination
0.46	GO:0007399	nervous system development
0.43	GO:0007423	sensory organ development
0.42	GO:0060324	face development
0.41	GO:0030154	cell differentiation
0.41	GO:0035270	endocrine system development
0.41	GO:0051961	negative regulation of nervous system development

0.54	GO:0003677	DNA binding
0.42	GO:0001106	RNA polymerase II transcription corepressor activity
0.40	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0003700	DNA binding transcription factor activity
0.35	GO:0008013	beta-catenin binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P53798|FDFT_MOUSE
Squalene synthase
Search

FDFT1

0.85	Farnesyl-diphosphate farnesyltransferase 1

0.80	GO:0006696	ergosterol biosynthetic process
0.51	GO:0045338	farnesyl diphosphate metabolic process
0.50	GO:0006695	cholesterol biosynthetic process

0.81	GO:0004310	farnesyl-diphosphate farnesyltransferase activity
0.81	GO:0051996	squalene synthase activity

0.55	GO:0005783	endoplasmic reticulum
0.45	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.44	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:2.5.1.21

GO:0004310

sp|P53808|PPCT_MOUSE
Phosphatidylcholine transfer protein
Search

PCTP

0.97	phosphatidylcholine transfer protein isoform X2

0.46	GO:0015914	phospholipid transport
0.38	GO:0008203	cholesterol metabolic process
0.35	GO:0006656	phosphatidylcholine biosynthetic process

0.69	GO:0008289	lipid binding
0.50	GO:0008525	phosphatidylcholine transporter activity
0.49	GO:0050997	quaternary ammonium group binding
0.47	GO:0070405	ammonium ion binding
0.37	GO:0043168	anion binding
0.33	GO:0005515	protein binding

0.43

GO:0005829

cytosol

sp|P53810|PIPNA_MOUSE
Phosphatidylinositol transfer protein alpha isoform
Search

PITPNA

0.96	Phosphatidylinositol transfer protein alpha

0.77	GO:0015914	phospholipid transport
0.52	GO:0007409	axonogenesis
0.36	GO:0043009	chordate embryonic development
0.36	GO:0035722	interleukin-12-mediated signaling pathway
0.34	GO:0007601	visual perception
0.33	GO:0006629	lipid metabolic process

0.78	GO:0005548	phospholipid transporter activity
0.56	GO:0031210	phosphatidylcholine binding
0.50	GO:0035091	phosphatidylinositol binding
0.36	GO:0070540	stearic acid binding
0.35	GO:1901611	phosphatidylglycerol binding
0.35	GO:0000062	fatty-acyl-CoA binding

0.52	GO:0043209	myelin sheath
0.44	GO:0005622	intracellular
0.36	GO:0070062	extracellular exosome
0.34	GO:0012505	endomembrane system
0.33	GO:0044422	organelle part
0.30	GO:0016020	membrane

sp|P53811|PIPNB_MOUSE
Phosphatidylinositol transfer protein beta isoform
Search

PITPNB

0.91	Phosphatidylinositol transfer protein beta

0.77	GO:0015914	phospholipid transport
0.42	GO:0035845	photoreceptor cell outer segment organization
0.36	GO:0001701	in utero embryonic development
0.35	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.35	GO:0006997	nucleus organization
0.33	GO:0006629	lipid metabolic process

0.78	GO:0005548	phospholipid transporter activity
0.54	GO:0031210	phosphatidylcholine binding
0.49	GO:0035091	phosphatidylinositol binding

0.45	GO:0005622	intracellular
0.40	GO:0012505	endomembrane system
0.37	GO:0043227	membrane-bounded organelle
0.36	GO:0043230	extracellular organelle
0.36	GO:0044422	organelle part
0.35	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

sp|P53986|MOT1_MOUSE
Monocarboxylate transporter 1
Search

SLC16A1

0.91	Solute carrier family 16 (Monocarboxylic acid transporters), member 1

0.80	GO:0035873	lactate transmembrane transport
0.76	GO:0051780	behavioral response to nutrient
0.74	GO:0032094	response to food
0.70	GO:0050796	regulation of insulin secretion
0.69	GO:0007098	centrosome cycle
0.68	GO:0042593	glucose homeostasis
0.54	GO:0006629	lipid metabolic process
0.44	GO:1901475	pyruvate transmembrane transport
0.40	GO:0071407	cellular response to organic cyclic compound

0.80	GO:0015129	lactate transmembrane transporter activity
0.43	GO:0050833	pyruvate transmembrane transporter activity
0.40	GO:0042803	protein homodimerization activity
0.34	GO:0097159	organic cyclic compound binding

0.67	GO:0005887	integral component of plasma membrane
0.65	GO:0005813	centrosome
0.64	GO:0030054	cell junction
0.53	GO:0005739	mitochondrion

sp|P53994|RAB2A_MOUSE
Ras-related protein Rab-2A
Search

RAB2A

0.94	RAS oncogene family member RAB2

0.62

GO:0007030

Golgi organization

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.58

GO:0005794

Golgi apparatus

sp|P53995|APC1_MOUSE
Anaphase-promoting complex subunit 1
Search

ANAPC1

0.89	LOW QUALITY PROTEIN: anaphase-promoting complex subunit 1

0.61	GO:0070979	protein K11-linked ubiquitination
0.37	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.37	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.36	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.36	GO:0051301	cell division
0.36	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process

0.34

GO:0005515

protein binding

0.79	GO:0005680	anaphase-promoting complex
0.34	GO:0005654	nucleoplasm
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P53996|CNBP_MOUSE
Cellular nucleic acid-binding protein
Search

CNBP

0.79	CCHC-type zinc finger, nucleic acid binding protein b

0.52	GO:0008284	positive regulation of cell proliferation
0.51	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:0000122	negative regulation of transcription by RNA polymerase II
0.39	GO:0014036	neural crest cell fate specification
0.38	GO:0048703	embryonic viscerocranium morphogenesis
0.38	GO:0051216	cartilage development
0.37	GO:0060322	head development
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:0006695	cholesterol biosynthetic process
0.33	GO:0000350	generation of catalytic spliceosome for second transesterification step

0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.51	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.37	GO:0003682	chromatin binding
0.33	GO:0005515	protein binding
0.33	GO:0016874	ligase activity

0.48	GO:0005783	endoplasmic reticulum
0.47	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33

GO:0016874

sp|P54071|IDHP_MOUSE
Isocitrate dehydrogenase [NADP], mitochondrial
Search

IDH2

0.51	Isocitrate dehydrogenase [NADP], mitochondrial

0.76	GO:0006102	isocitrate metabolic process
0.64	GO:0006099	tricarboxylic acid cycle
0.40	GO:0006103	2-oxoglutarate metabolic process
0.40	GO:1904465	negative regulation of matrix metallopeptidase secretion
0.40	GO:0006097	glyoxylate cycle
0.39	GO:1903976	negative regulation of glial cell migration
0.39	GO:0060253	negative regulation of glial cell proliferation
0.37	GO:0006741	NADP biosynthetic process
0.34	GO:0007005	mitochondrion organization

0.74	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.64	GO:0051287	NAD binding
0.61	GO:0000287	magnesium ion binding

0.49	GO:0005777	peroxisome
0.46	GO:0005829	cytosol
0.44	GO:0005739	mitochondrion
0.43	GO:0019866	organelle inner membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0031974	membrane-enclosed lumen
0.30	GO:0016021	integral component of membrane

0.74

EC:1.1.1.42

GO:0004450

sp|P54099|DPOG1_MOUSE
DNA polymerase subunit gamma-1
Search

POLG

0.95	DNA polymerase gamma, catalytic subunit

0.65	GO:0071897	DNA biosynthetic process
0.65	GO:0006260	DNA replication
0.63	GO:0006287	base-excision repair, gap-filling
0.51	GO:0032042	mitochondrial DNA metabolic process
0.42	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.42	GO:0055093	response to hyperoxia
0.42	GO:0007568	aging
0.42	GO:0010332	response to gamma radiation
0.42	GO:0071333	cellular response to glucose stimulus
0.39	GO:0009416	response to light stimulus

0.69	GO:0003887	DNA-directed DNA polymerase activity
0.60	GO:0002020	protease binding
0.56	GO:0003682	chromatin binding
0.54	GO:0003677	DNA binding
0.45	GO:0008408	3'-5' exonuclease activity

0.84	GO:0005760	gamma DNA polymerase complex
0.60	GO:0042645	mitochondrial nucleoid
0.46	GO:0043234	protein complex
0.42	GO:0043195	terminal bouton
0.38	GO:0070062	extracellular exosome
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0003887

sp|P54103|DNJC2_MOUSE
DnaJ homolog subfamily C member 2
Search

DNAJC2

0.93	DnaJ like protein subfamily C member 2

0.57	GO:2000279	negative regulation of DNA biosynthetic process
0.52	GO:0045893	positive regulation of transcription, DNA-templated
0.47	GO:0006260	DNA replication
0.40	GO:0016569	covalent chromatin modification
0.37	GO:0006351	transcription, DNA-templated
0.36	GO:1900034	regulation of cellular response to heat
0.36	GO:0051083	'de novo' cotranslational protein folding
0.35	GO:0030308	negative regulation of cell growth
0.35	GO:0032781	positive regulation of ATPase activity

0.62	GO:0061649	ubiquitin modification-dependent histone binding
0.58	GO:0030544	Hsp70 protein binding
0.54	GO:0003682	chromatin binding
0.53	GO:0003677	DNA binding
0.35	GO:0001671	ATPase activator activity
0.34	GO:0003723	RNA binding

0.58	GO:0005634	nucleus
0.49	GO:0005829	cytosol
0.48	GO:0012505	endomembrane system
0.45	GO:0031967	organelle envelope
0.45	GO:0031090	organelle membrane
0.34	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

sp|P54116|STOM_MOUSE
Erythrocyte band 7 integral membrane protein
Search

STOM

0.83	Erythrocyte band 7 integral membrane protein stomatin

0.44	GO:1901585	regulation of acid-sensing ion channel activity
0.43	GO:0044829	positive regulation by host of viral genome replication
0.43	GO:0090314	positive regulation of protein targeting to membrane
0.40	GO:0051260	protein homooligomerization
0.37	GO:0043312	neutrophil degranulation

0.40	GO:0070063	RNA polymerase binding
0.40	GO:0042803	protein homodimerization activity

0.66	GO:0005887	integral component of plasma membrane
0.41	GO:0045121	membrane raft
0.40	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0042470	melanosome
0.39	GO:0005783	endoplasmic reticulum
0.38	GO:0005856	cytoskeleton
0.38	GO:0035579	specific granule membrane
0.38	GO:0035577	azurophil granule membrane
0.38	GO:0070821	tertiary granule membrane
0.37	GO:0072562	blood microparticle

sp|P54130|FGF9_MOUSE
Fibroblast growth factor 9
Search

FGF9

0.62	Fibroblast growth factor

0.82	GO:0008543	fibroblast growth factor receptor signaling pathway
0.75	GO:0010469	regulation of receptor activity
0.59	GO:0060043	regulation of cardiac muscle cell proliferation
0.58	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.57	GO:0048839	inner ear development
0.56	GO:0060484	lung-associated mesenchyme development
0.56	GO:0032927	positive regulation of activin receptor signaling pathway
0.56	GO:0008584	male gonad development
0.56	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
0.56	GO:0048505	regulation of timing of cell differentiation

0.83	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.48	GO:0090722	receptor-receptor interaction
0.41	GO:0008201	heparin binding
0.38	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.37	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.36	GO:0004713	protein tyrosine kinase activity
0.34	GO:0043395	heparan sulfate proteoglycan binding

0.65	GO:0005576	extracellular region
0.38	GO:0031982	vesicle
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.38	EC:2.7.1.153	GO:0046934
0.38	KEGG:R04545	GO:0046934

sp|P54227|STMN1_MOUSE
Stathmin
Search

STMN1

0.86

Stathmin

0.84	GO:0031110	regulation of microtubule polymerization or depolymerization
0.55	GO:0007019	microtubule depolymerization
0.55	GO:0070495	negative regulation of thrombin-activated receptor signaling pathway
0.54	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity
0.54	GO:0048012	hepatocyte growth factor receptor signaling pathway
0.53	GO:0051497	negative regulation of stress fiber assembly
0.53	GO:0061436	establishment of skin barrier
0.53	GO:0035024	negative regulation of Rho protein signal transduction
0.52	GO:0032272	negative regulation of protein polymerization
0.51	GO:0031175	neuron projection development

0.49	GO:0015631	tubulin binding
0.38	GO:0048306	calcium-dependent protein binding
0.37	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity
0.33	GO:0004871	signal transducer activity

0.46	GO:0043005	neuron projection
0.45	GO:0005829	cytosol
0.40	GO:0005874	microtubule
0.37	GO:0030027	lamellipodium
0.37	GO:0043025	neuronal cell body
0.37	GO:0030427	site of polarized growth
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0120038	plasma membrane bounded cell projection part
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.37

EC:3.1.1.47

GO:0003847

sp|P54254|ATX1_MOUSE
Ataxin-1
Search

ATXN1

0.97

Ataxin-1

0.56	GO:0051168	nuclear export
0.54	GO:0045892	negative regulation of transcription, DNA-templated
0.41	GO:0035176	social behavior
0.40	GO:0007613	memory
0.40	GO:0007612	learning
0.40	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway
0.40	GO:0060252	positive regulation of glial cell proliferation
0.39	GO:0048286	lung alveolus development
0.39	GO:0007420	brain development
0.39	GO:0007632	visual behavior

0.66	GO:0034046	poly(G) binding
0.63	GO:0008266	poly(U) RNA binding
0.62	GO:0043621	protein self-association
0.61	GO:0008022	protein C-terminus binding
0.55	GO:0042802	identical protein binding
0.38	GO:0003682	chromatin binding
0.35	GO:0003677	DNA binding

0.66	GO:0042272	nuclear RNA export factor complex
0.64	GO:0042405	nuclear inclusion body
0.62	GO:0016363	nuclear matrix
0.55	GO:0005730	nucleolus
0.52	GO:0005829	cytosol
0.38	GO:0098794	postsynapse
0.30	GO:0016020	membrane

sp|P54265|DMPK_MOUSE
Myotonin-protein kinase
Search

DMPK

0.97	Dystrophia myotonica-protein kinase

0.63	GO:0006468	protein phosphorylation
0.58	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling
0.57	GO:0014853	regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
0.56	GO:0010657	muscle cell apoptotic process
0.55	GO:0051823	regulation of synapse structural plasticity
0.54	GO:0006998	nuclear envelope organization
0.53	GO:0010830	regulation of myotube differentiation
0.53	GO:0008016	regulation of heart contraction
0.53	GO:0002028	regulation of sodium ion transport
0.52	GO:0006874	cellular calcium ion homeostasis

0.70	GO:0004674	protein serine/threonine kinase activity
0.56	GO:0017020	myosin phosphatase regulator activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0046872	metal ion binding
0.38	GO:0031072	heat shock protein binding
0.34	GO:0042802	identical protein binding
0.33	GO:0032403	protein complex binding

0.55	GO:0033017	sarcoplasmic reticulum membrane
0.53	GO:0031307	integral component of mitochondrial outer membrane
0.43	GO:0031965	nuclear membrane
0.41	GO:0005886	plasma membrane
0.37	GO:0005829	cytosol
0.36	GO:0042641	actomyosin
0.36	GO:0031252	cell leading edge
0.34	GO:0005815	microtubule organizing center
0.34	GO:0070062	extracellular exosome
0.33	GO:0005911	cell-cell junction

0.70

GO:0004674

sp|P54276|MSH6_MOUSE
DNA mismatch repair protein Msh6
Search

MSH6

0.83	DNA mismatch repair protein MutS-homolog 6

0.75	GO:0006298	mismatch repair
0.60	GO:0051096	positive regulation of helicase activity
0.59	GO:0016446	somatic hypermutation of immunoglobulin genes
0.58	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response
0.57	GO:0002312	B cell activation involved in immune response
0.57	GO:0045830	positive regulation of isotype switching
0.57	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.56	GO:0045910	negative regulation of DNA recombination
0.55	GO:0008340	determination of adult lifespan
0.54	GO:0009411	response to UV

0.76	GO:0030983	mismatched DNA binding
0.61	GO:0032405	MutLalpha complex binding
0.61	GO:0032357	oxidized purine DNA binding
0.59	GO:0000400	four-way junction DNA binding
0.57	GO:0140034	methylation-dependent protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.55	GO:0042393	histone binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0032301	MutSalpha complex
0.50	GO:0000790	nuclear chromatin
0.50	GO:0005794	Golgi apparatus
0.50	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol

0.46

GO:0016887

sp|P54279|PMS2_MOUSE
Mismatch repair endonuclease PMS2
Search

PMS2

0.94	Postmeiotic segregation increased 2 nirs variant 5

0.75	GO:0006298	mismatch repair
0.53	GO:0016446	somatic hypermutation of immunoglobulin genes
0.51	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.41	GO:0048298	positive regulation of isotype switching to IgA isotypes
0.41	GO:0048304	positive regulation of isotype switching to IgG isotypes
0.40	GO:0016447	somatic recombination of immunoglobulin gene segments
0.38	GO:0042493	response to drug
0.36	GO:0002565	somatic diversification of immune receptors via gene conversion
0.36	GO:0051321	meiotic cell cycle
0.35	GO:0035822	gene conversion

0.75	GO:0030983	mismatched DNA binding
0.60	GO:0032407	MutSalpha complex binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0003697	single-stranded DNA binding
0.53	GO:0004519	endonuclease activity
0.41	GO:0016887	ATPase activity
0.33	GO:0003684	damaged DNA binding
0.33	GO:0016972	thiol oxidase activity

0.54	GO:0036464	cytoplasmic ribonucleoprotein granule
0.52	GO:0032389	MutLalpha complex
0.50	GO:0015630	microtubule cytoskeleton
0.49	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.41

GO:0016887

sp|P54285|CACB3_MOUSE
Voltage-dependent L-type calcium channel subunit beta-3
Search

CACNB3

0.97	Voltage-dependent calcium channel beta subunit

0.75	GO:0070588	calcium ion transmembrane transport
0.54	GO:0050852	T cell receptor signaling pathway
0.49	GO:1901385	regulation of voltage-gated calcium channel activity
0.48	GO:0007528	neuromuscular junction development
0.46	GO:0007268	chemical synaptic transmission
0.40	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.40	GO:0098903	regulation of membrane repolarization during action potential
0.39	GO:0060402	calcium ion transport into cytosol
0.38	GO:0072659	protein localization to plasma membrane
0.37	GO:0035637	multicellular organismal signaling

0.80	GO:0005245	voltage-gated calcium channel activity
0.38	GO:0019901	protein kinase binding

0.79	GO:0005891	voltage-gated calcium channel complex
0.42	GO:0030315	T-tubule
0.38	GO:0016324	apical plasma membrane
0.35	GO:0005829	cytosol
0.33	GO:0009898	cytoplasmic side of plasma membrane
0.33	GO:0045202	synapse

sp|P54310|LIPS_MOUSE
Hormone-sensitive lipase
Search

LIPE

0.88	Hormone-sensitive lipase variant B

0.83	GO:0008203	cholesterol metabolic process
0.72	GO:0016042	lipid catabolic process
0.57	GO:0046339	diacylglycerol metabolic process
0.55	GO:0006641	triglyceride metabolic process
0.52	GO:0001676	long-chain fatty acid metabolic process
0.49	GO:0072329	monocarboxylic acid catabolic process
0.43	GO:0006363	termination of RNA polymerase I transcription
0.43	GO:0006361	transcription initiation from RNA polymerase I promoter
0.36	GO:0007565	female pregnancy
0.35	GO:0019236	response to pheromone

0.75	GO:0016298	lipase activity
0.52	GO:0019901	protein kinase binding
0.50	GO:0052689	carboxylic ester hydrolase activity
0.47	GO:0017171	serine hydrolase activity
0.43	GO:0042134	rRNA primary transcript binding

0.55	GO:0005811	lipid droplet
0.49	GO:0005829	cytosol
0.43	GO:0005901	caveola
0.37	GO:0005634	nucleus
0.37	GO:0005739	mitochondrion
0.35	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.75	EC:3.1.1	GO:0016298
0.50	KEGG:R00630	GO:0052689

sp|P54320|ELN_MOUSE
Elastin
Search

ELN

0.97	Tropoelastin 1

0.55	GO:0043149	stress fiber assembly
0.52	GO:0007519	skeletal muscle tissue development
0.51	GO:0030198	extracellular matrix organization
0.50	GO:0030833	regulation of actin filament polymerization
0.41	GO:0071298	cellular response to L-ascorbic acid
0.39	GO:0071280	cellular response to copper ion
0.39	GO:0071549	cellular response to dexamethasone stimulus
0.39	GO:0055093	response to hyperoxia
0.39	GO:0001974	blood vessel remodeling
0.39	GO:0071300	cellular response to retinoic acid

0.79	GO:0005201	extracellular matrix structural constituent
0.52	GO:0050840	extracellular matrix binding
0.39	GO:0097493	structural molecule activity conferring elasticity
0.38	GO:0005515	protein binding
0.35	GO:0016740	transferase activity
0.33	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0046872	metal ion binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0005578	proteinaceous extracellular matrix
0.57	GO:0071953	elastic fiber
0.43	GO:0005739	mitochondrion
0.37	GO:0005615	extracellular space
0.32	GO:0019867	outer membrane
0.30	GO:0016021	integral component of membrane

0.35

GO:0016740

sp|P54369|OAZ1_MOUSE
Ornithine decarboxylase antizyme 1
Search

OAZ1

0.88	Ornithine decarboxylase antizyme

0.73	GO:0006595	polyamine metabolic process
0.70	GO:0043086	negative regulation of catalytic activity
0.56	GO:1902268	negative regulation of polyamine transmembrane transport
0.55	GO:0045732	positive regulation of protein catabolic process
0.54	GO:0090316	positive regulation of intracellular protein transport
0.42	GO:0042401	cellular biogenic amine biosynthetic process
0.36	GO:0006521	regulation of cellular amino acid metabolic process
0.34	GO:0006368	transcription elongation from RNA polymerase II promoter

0.84	GO:0008073	ornithine decarboxylase inhibitor activity
0.36	GO:0005515	protein binding

0.66	GO:0005829	cytosol
0.41	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0043234	protein complex
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P54615|OSTR_MOUSE
Osteocalcin-related protein
Search

BGLAP

0.88	Osteocalcin

0.85	GO:0030500	regulation of bone mineralization
0.68	GO:0033280	response to vitamin D
0.66	GO:0001649	osteoblast differentiation
0.66	GO:0031214	biomineral tissue development
0.54	GO:0071495	cellular response to endogenous stimulus
0.53	GO:0071772	response to BMP
0.53	GO:0071310	cellular response to organic substance
0.50	GO:0044342	type B pancreatic cell proliferation
0.49	GO:0009725	response to hormone
0.49	GO:1901701	cellular response to oxygen-containing compound

0.70	GO:0005509	calcium ion binding
0.52	GO:0046848	hydroxyapatite binding
0.50	GO:0008147	structural constituent of bone

0.66	GO:0005576	extracellular region
0.46	GO:0005737	cytoplasm
0.46	GO:0043204	perikaryon
0.45	GO:0030425	dendrite
0.42	GO:0031982	vesicle
0.41	GO:0012505	endomembrane system
0.37	GO:0043231	intracellular membrane-bounded organelle

sp|P54726|RD23A_MOUSE
UV excision repair protein RAD23 homolog A
Search

RAD23A

0.97	UV excision repair protein RAD23 like protein A

0.76	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.72	GO:0006289	nucleotide-excision repair
0.61	GO:0045070	positive regulation of viral genome replication
0.60	GO:0031648	protein destabilization
0.60	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
0.57	GO:1901800	positive regulation of proteasomal protein catabolic process
0.56	GO:0045787	positive regulation of cell cycle
0.38	GO:0007283	spermatogenesis
0.36	GO:0051276	chromosome organization
0.36	GO:0016579	protein deubiquitination

0.72	GO:0003684	damaged DNA binding
0.62	GO:1990381	ubiquitin-specific protease binding
0.61	GO:0031593	polyubiquitin modification-dependent protein binding
0.56	GO:0019900	kinase binding
0.35	GO:0003697	single-stranded DNA binding

0.61	GO:0005634	nucleus
0.54	GO:0005815	microtubule organizing center
0.52	GO:0005829	cytosol
0.51	GO:0031974	membrane-enclosed lumen
0.46	GO:0043234	protein complex
0.39	GO:1905369	endopeptidase complex
0.38	GO:1990391	DNA repair complex

sp|P54728|RD23B_MOUSE
UV excision repair protein RAD23 homolog B
Search

RAD23B

0.91	UV excision repair protein RAD23 like protein B

0.77	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.73	GO:0006289	nucleotide-excision repair
0.53	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
0.50	GO:0007283	spermatogenesis
0.45	GO:0051276	chromosome organization
0.38	GO:0048568	embryonic organ development
0.34	GO:0065004	protein-DNA complex assembly
0.34	GO:0016579	protein deubiquitination
0.34	GO:0006457	protein folding

0.72	GO:0003684	damaged DNA binding
0.53	GO:0031593	polyubiquitin modification-dependent protein binding
0.34	GO:0003697	single-stranded DNA binding

0.61	GO:0005634	nucleus
0.49	GO:1990391	DNA repair complex
0.46	GO:0005829	cytosol
0.46	GO:0031974	membrane-enclosed lumen
0.43	GO:0043234	protein complex
0.42	GO:0044446	intracellular organelle part
0.38	GO:1905369	endopeptidase complex
0.30	GO:0016020	membrane

sp|P54729|NUB1_MOUSE
NEDD8 ultimate buster 1
Search

NUB1

0.96	Negative regulator of ubiquitin like proteins 1

0.50	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.47	GO:0034341	response to interferon-gamma
0.46	GO:0034612	response to tumor necrosis factor
0.46	GO:0006511	ubiquitin-dependent protein catabolic process
0.46	GO:0016567	protein ubiquitination
0.39	GO:0043687	post-translational protein modification

0.36

GO:0005515

protein binding

0.71	GO:0005730	nucleolus
0.67	GO:0005829	cytosol

sp|P54731|FAF1_MOUSE
FAS-associated factor 1
Search

FAF1

0.44	Phosphoglycerate kinase

0.74	GO:0008219	cell death
0.61	GO:0007253	cytoplasmic sequestering of NF-kappaB
0.60	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.54	GO:0031334	positive regulation of protein complex assembly
0.54	GO:0042176	regulation of protein catabolic process
0.53	GO:0030155	regulation of cell adhesion
0.45	GO:0060037	pharyngeal system development
0.44	GO:0051216	cartilage development
0.35	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.35	GO:0045859	regulation of protein kinase activity

0.59	GO:0051059	NF-kappaB binding
0.55	GO:0043130	ubiquitin binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.54	GO:0019901	protein kinase binding
0.53	GO:0031072	heat shock protein binding
0.53	GO:0019904	protein domain specific binding
0.35	GO:0019887	protein kinase regulator activity
0.35	GO:0004618	phosphoglycerate kinase activity
0.33	GO:0051082	unfolded protein binding
0.32	GO:0004674	protein serine/threonine kinase activity

0.58	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex
0.54	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0005635	nuclear envelope
0.49	GO:0005829	cytosol
0.36	GO:0031265	CD95 death-inducing signaling complex
0.30	GO:0016021	integral component of membrane

0.35	EC:2.7.2.3	GO:0004618
0.35	KEGG:R01512	GO:0004618

sp|P54751|SIA4A_MOUSE
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
Search

ST3GAL1

0.93	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2

0.83	GO:0097503	sialylation
0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.60	GO:0036211	protein modification process
0.56	GO:0044267	cellular protein metabolic process
0.47	GO:0009311	oligosaccharide metabolic process
0.43	GO:0016310	phosphorylation
0.43	GO:0030259	lipid glycosylation
0.41	GO:0009247	glycolipid biosynthetic process
0.40	GO:0016051	carbohydrate biosynthetic process

0.84

GO:0008373

sialyltransferase activity

0.69	GO:0005794	Golgi apparatus
0.45	GO:0098588	bounding membrane of organelle
0.44	GO:0031984	organelle subcompartment
0.39	GO:0005576	extracellular region
0.37	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:2.4.99

GO:0008373

sp|P54754|EPHB3_MOUSE
Ephrin type-B receptor 3
Search

EPHB3

0.96	Eph receptor B3

0.84	GO:0048013	ephrin receptor signaling pathway
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.63	GO:0034446	substrate adhesion-dependent cell spreading
0.59	GO:0046777	protein autophosphorylation
0.58	GO:0022038	corpus callosum development
0.58	GO:0060997	dendritic spine morphogenesis
0.57	GO:0016477	cell migration
0.57	GO:0021952	central nervous system projection neuron axonogenesis
0.57	GO:0031290	retinal ganglion cell axon guidance
0.57	GO:0007413	axonal fasciculation

0.85	GO:0005003	ephrin receptor activity
0.58	GO:0008046	axon guidance receptor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.67

GO:0005887

integral component of plasma membrane

sp|P54761|EPHB4_MOUSE
Ephrin type-B receptor 4
Search

EPHB4

0.88	Eph receptor B4

0.84	GO:0048013	ephrin receptor signaling pathway
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.65	GO:0002042	cell migration involved in sprouting angiogenesis
0.62	GO:0046777	protein autophosphorylation
0.56	GO:0007155	cell adhesion
0.48	GO:0035475	angioblast cell migration involved in selective angioblast sprouting
0.45	GO:0060026	convergent extension
0.44	GO:0070121	Kupffer's vesicle development
0.44	GO:0022038	corpus callosum development
0.44	GO:0060997	dendritic spine morphogenesis

0.84	GO:0005003	ephrin receptor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0008046	axon guidance receptor activity

0.65	GO:0005887	integral component of plasma membrane
0.37	GO:0070062	extracellular exosome

sp|P54763|EPHB2_MOUSE
Ephrin type-B receptor 2
Search

EPHB2

0.91	Eph receptor B2

0.84	GO:0048013	ephrin receptor signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.71	GO:0106028	neuron projection retraction
0.71	GO:0099557	trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission
0.71	GO:1904782	negative regulation of NMDA glutamate receptor activity
0.70	GO:1904783	positive regulation of NMDA glutamate receptor activity
0.69	GO:0048170	positive regulation of long-term neuronal synaptic plasticity
0.69	GO:0051389	inactivation of MAPKK activity
0.68	GO:0031915	positive regulation of synaptic plasticity
0.68	GO:0021631	optic nerve morphogenesis

0.85	GO:0005003	ephrin receptor activity
0.68	GO:0008046	axon guidance receptor activity
0.65	GO:0001540	amyloid-beta binding
0.57	GO:0042802	identical protein binding
0.56	GO:0005102	receptor binding
0.55	GO:0044877	macromolecular complex binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding

0.66	GO:0005887	integral component of plasma membrane
0.61	GO:0043025	neuronal cell body
0.61	GO:0030425	dendrite
0.61	GO:0030424	axon
0.48	GO:0005634	nucleus

sp|P54775|PRS6B_MOUSE
26S protease regulatory subunit 6B
Search

PSMC4

0.82	Proteasome (Prosome, macropain) 26S subunit, ATPase, 4

0.81	GO:1901800	positive regulation of proteasomal protein catabolic process
0.69	GO:0030163	protein catabolic process
0.53	GO:0006508	proteolysis
0.52	GO:0001824	blastocyst development
0.48	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.46	GO:0034976	response to endoplasmic reticulum stress
0.46	GO:0010243	response to organonitrogen compound
0.44	GO:0043632	modification-dependent macromolecule catabolic process
0.38	GO:0044267	cellular protein metabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition

0.82	GO:0036402	proteasome-activating ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0008233	peptidase activity
0.47	GO:0017025	TBP-class protein binding

0.56	GO:1905369	endopeptidase complex
0.49	GO:0005829	cytosol
0.48	GO:0043234	protein complex
0.45	GO:0005634	nucleus
0.42	GO:0070013	intracellular organelle lumen
0.39	GO:0044446	intracellular organelle part
0.39	GO:0016234	inclusion body
0.37	GO:0045202	synapse
0.30	GO:0016020	membrane

0.52

GO:0008233

sp|P54797|TNG2_MOUSE
Transport and Golgi organization 2 homolog
Search

TANGO2

0.93	Transport and Golgi organization protein 2

0.71	GO:0005794	Golgi apparatus
0.40	GO:0005739	mitochondrion

sp|P54818|GALC_MOUSE
Galactocerebrosidase
Search

GALC

0.93	galactocerebrosidase precursor

0.86	GO:0006683	galactosylceramide catabolic process
0.34	GO:0045859	regulation of protein kinase activity

0.86	GO:0004336	galactosylceramidase activity
0.34	GO:0019887	protein kinase regulator activity

0.46	GO:0005764	lysosome
0.44	GO:0005739	mitochondrion
0.38	GO:0070062	extracellular exosome
0.35	GO:0005775	vacuolar lumen
0.35	GO:0005956	protein kinase CK2 complex
0.30	GO:0016020	membrane

0.86

EC:3.2.1.46

GO:0004336

sp|P54822|PUR8_MOUSE
Adenylosuccinate lyase
Search

ADSL

0.48	Adenylosuccinate lyase

0.75	GO:0044208	'de novo' AMP biosynthetic process
0.70	GO:0006189	'de novo' IMP biosynthetic process
0.52	GO:0051262	protein tetramerization
0.40	GO:0014850	response to muscle activity
0.39	GO:0001666	response to hypoxia
0.39	GO:0007584	response to nutrient
0.38	GO:0042594	response to starvation
0.36	GO:0009060	aerobic respiration

0.78	GO:0004018	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity
0.78	GO:0070626	(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity

0.48	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion

0.78	EC:4.3.2.2	GO:0004018
0.78	KEGG:R01083	GO:0004018

sp|P54823|DDX6_MOUSE
Probable ATP-dependent RNA helicase DDX6
Search

DDX6

0.93	ATP-dependent RNA helicase DDX6 protein 1

0.48	GO:0033962	cytoplasmic mRNA processing body assembly
0.48	GO:0019074	viral RNA genome packaging
0.46	GO:0019827	stem cell population maintenance
0.46	GO:0045665	negative regulation of neuron differentiation
0.42	GO:0010501	RNA secondary structure unwinding
0.40	GO:0006417	regulation of translation
0.38	GO:0007283	spermatogenesis
0.37	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.37	GO:0034063	stress granule assembly
0.35	GO:0009408	response to heat

0.67	GO:0004386	helicase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.45	GO:0045296	cadherin binding
0.44	GO:0019904	protein domain specific binding
0.42	GO:0008186	RNA-dependent ATPase activity
0.38	GO:0140098	catalytic activity, acting on RNA

0.49	GO:0036464	cytoplasmic ribonucleoprotein granule
0.46	GO:0016442	RISC complex
0.42	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.40	GO:0097227	sperm annulus
0.40	GO:0001520	outer dense fiber
0.39	GO:0031974	membrane-enclosed lumen
0.39	GO:0060293	germ plasm
0.39	GO:0000792	heterochromatin
0.35	GO:0005739	mitochondrion

0.35

EC:3.2.1.28

GO:0004555

sp|P54830|PTN5_MOUSE
Tyrosine-protein phosphatase non-receptor type 5
Search

PTPN5

0.97	Tyrosine-protein phosphatase non-receptor type 5

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.45	GO:0038128	ERBB2 signaling pathway
0.43	GO:0010633	negative regulation of epithelial cell migration
0.43	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.43	GO:0001701	in utero embryonic development
0.36	GO:1903492	response to acetylsalicylate
0.35	GO:0035902	response to immobilization stress
0.35	GO:1900273	positive regulation of long-term synaptic potentiation
0.35	GO:0033160	positive regulation of protein import into nucleus, translocation
0.35	GO:0001975	response to amphetamine

0.75	GO:0004725	protein tyrosine phosphatase activity
0.56	GO:0001784	phosphotyrosine residue binding
0.42	GO:0019901	protein kinase binding
0.35	GO:0035254	glutamate receptor binding
0.34	GO:0019198	transmembrane receptor protein phosphatase activity

0.41	GO:0030054	cell junction
0.40	GO:0005829	cytosol
0.36	GO:0005783	endoplasmic reticulum
0.36	GO:0005886	plasma membrane
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:1990635	proximal dendrite
0.35	GO:0031984	organelle subcompartment
0.35	GO:0043204	perikaryon
0.34	GO:0030424	axon
0.34	GO:0005654	nucleoplasm

0.75

GO:0004725

sp|P54841|MAFB_MOUSE
Transcription factor MafB
Search

MAFB

0.94	Basic domain leucine zipper transcription factor

0.61	GO:0021572	rhombomere 6 development
0.60	GO:0021598	abducens nerve morphogenesis
0.60	GO:0021571	rhombomere 5 development
0.59	GO:0035283	central nervous system segmentation
0.59	GO:0045647	negative regulation of erythrocyte differentiation
0.59	GO:0021603	cranial nerve formation
0.58	GO:0045671	negative regulation of osteoclast differentiation
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0008134	transcription factor binding
0.39	GO:0042803	protein homodimerization activity
0.39	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P54843|MAF_MOUSE
Transcription factor Maf
Search

MAF

0.87	V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba

0.58	GO:0070306	lens fiber cell differentiation
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0006351	transcription, DNA-templated
0.54	GO:0032330	regulation of chondrocyte differentiation
0.53	GO:0001816	cytokine production
0.53	GO:0048839	inner ear development
0.50	GO:0051254	positive regulation of RNA metabolic process
0.50	GO:0010557	positive regulation of macromolecule biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0003677	DNA binding
0.39	GO:0001067	regulatory region nucleic acid binding
0.39	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.36	GO:0000785	chromatin
0.35	GO:0031974	membrane-enclosed lumen
0.35	GO:0042025	host cell nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P54846|NRL_MOUSE
Neural retina-specific leucine zipper protein
Search

NRL

0.87	Leucine zipper transcription factor

0.73	GO:0007468	regulation of rhodopsin gene expression
0.72	GO:0046548	retinal rod cell development
0.58	GO:0006366	transcription by RNA polymerase II
0.57	GO:0045944	positive regulation of transcription by RNA polymerase II
0.43	GO:0070306	lens fiber cell differentiation
0.42	GO:0048839	inner ear development
0.42	GO:0032330	regulation of chondrocyte differentiation
0.41	GO:0001816	cytokine production
0.40	GO:0000122	negative regulation of transcription by RNA polymerase II
0.38	GO:0007263	nitric oxide mediated signal transduction

0.64	GO:0043522	leucine zipper domain binding
0.61	GO:0003700	DNA binding transcription factor activity
0.61	GO:1990841	promoter-specific chromatin binding
0.59	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0003713	transcription coactivator activity
0.36	GO:0008134	transcription factor binding
0.35	GO:0046982	protein heterodimerization activity
0.33	GO:0042803	protein homodimerization activity
0.32	GO:0003735	structural constituent of ribosome

0.61	GO:0005634	nucleus
0.51	GO:0005829	cytosol
0.50	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.35	GO:0005667	transcription factor complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0042025	host cell nucleus
0.32	GO:0030529	intracellular ribonucleoprotein complex

sp|P54869|HMCS2_MOUSE
Hydroxymethylglutaryl-CoA synthase, mitochondrial
Search

HMGCS2

0.67	3-hydroxy-3-methylglutaryl coenzyme A synthase

0.78	GO:0016126	sterol biosynthetic process
0.71	GO:0008299	isoprenoid biosynthetic process
0.44	GO:0014003	oligodendrocyte development
0.35	GO:0033197	response to vitamin E
0.35	GO:0071372	cellular response to follicle-stimulating hormone stimulus
0.35	GO:0071397	cellular response to cholesterol
0.35	GO:0009645	response to low light intensity stimulus
0.35	GO:0071404	cellular response to low-density lipoprotein particle stimulus
0.34	GO:0046690	response to tellurium ion
0.34	GO:0008584	male gonad development

0.83	GO:0004421	hydroxymethylglutaryl-CoA synthase activity
0.34	GO:0008009	chemokine activity
0.34	GO:0042803	protein homodimerization activity
0.33	GO:0043177	organic acid binding
0.33	GO:0016853	isomerase activity
0.32	GO:0008144	drug binding

0.43	GO:0005739	mitochondrion
0.43	GO:0019866	organelle inner membrane
0.33	GO:0005829	cytosol
0.33	GO:0005576	extracellular region

0.83	EC:2.3.3.10	GO:0004421
0.83	KEGG:R01978	GO:0004421

sp|P54923|ADPRH_MOUSE
[Protein ADP-ribosylarginine] hydrolase
Search

ADPRH

0.97	ADP-ribosylarginine hydrolase

0.83	GO:0051725	protein de-ADP-ribosylation
0.50	GO:0031338	regulation of vesicle fusion
0.50	GO:0090630	activation of GTPase activity
0.44	GO:0006886	intracellular protein transport
0.36	GO:0006629	lipid metabolic process

0.84	GO:0003875	ADP-ribosylarginine hydrolase activity
0.60	GO:0000287	magnesium ion binding
0.52	GO:0030955	potassium ion binding
0.48	GO:0017137	Rab GTPase binding
0.47	GO:0005096	GTPase activator activity
0.37	GO:0052689	carboxylic ester hydrolase activity

0.44	GO:0012505	endomembrane system
0.36	GO:0005576	extracellular region
0.36	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.84	EC:3.2.2.19	GO:0003875
0.37	KEGG:R00630	GO:0052689

sp|P54987|IRG1_MOUSE
Cis-aconitate decarboxylase
Search

ACOD1

0.97	Cis-aconitate decarboxylase

0.60	GO:0072573	tolerance induction to lipopolysaccharide
0.57	GO:0002760	positive regulation of antimicrobial humoral response
0.54	GO:0006952	defense response
0.49	GO:0019679	propionate metabolic process, methylcitrate cycle
0.45	GO:2000377	regulation of reactive oxygen species metabolic process
0.41	GO:0071393	cellular response to progesterone stimulus
0.40	GO:0034136	negative regulation of toll-like receptor 2 signaling pathway
0.40	GO:0034144	negative regulation of toll-like receptor 4 signaling pathway
0.39	GO:0035458	cellular response to interferon-beta
0.39	GO:0009611	response to wounding

0.62	GO:0047613	aconitate decarboxylase activity
0.49	GO:0047547	2-methylcitrate dehydratase activity
0.33	GO:0008270	zinc ion binding

0.41	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

0.62	EC:4.1.1.6	GO:0047613
0.62	KEGG:R02243	GO:0047613

sp|P55002|MFAP2_MOUSE
Microfibrillar-associated protein 2
Search

MFAP2

0.97	Microfibril-associated glycoprotein 1

0.64	GO:0048048	embryonic eye morphogenesis
0.64	GO:0048050	post-embryonic eye morphogenesis
0.43	GO:0001568	blood vessel development
0.39	GO:0030097	hemopoiesis
0.39	GO:0036344	platelet morphogenesis
0.37	GO:0048646	anatomical structure formation involved in morphogenesis
0.36	GO:0030198	extracellular matrix organization
0.35	GO:0006812	cation transport
0.35	GO:0097435	supramolecular fiber organization
0.34	GO:0006099	tricarboxylic acid cycle

0.40	GO:0070051	fibrinogen binding
0.39	GO:0001968	fibronectin binding
0.35	GO:0016887	ATPase activity
0.35	GO:0051538	3 iron, 4 sulfur cluster binding
0.35	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046872	metal ion binding
0.34	GO:0051537	2 iron, 2 sulfur cluster binding

0.86	GO:0001527	microfibril
0.40	GO:0005578	proteinaceous extracellular matrix
0.35	GO:0005615	extracellular space
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.35	EC:3.6.1.3	GO:0016887
0.35	KEGG:R02164	GO:0008177

sp|P55012|S12A2_MOUSE
Solute carrier family 12 member 2
Search

SLC12A2

0.75	Bumetanide-sensitive Na-K-Cl cotransporter 1

0.76	GO:1902476	chloride transmembrane transport
0.56	GO:0070634	transepithelial ammonium transport
0.55	GO:0030321	transepithelial chloride transport
0.51	GO:0072488	ammonium transmembrane transport
0.47	GO:0048798	swim bladder inflation
0.44	GO:0042472	inner ear morphogenesis
0.37	GO:0060763	mammary duct terminal end bud growth
0.36	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
0.36	GO:0060444	branching involved in mammary gland duct morphogenesis
0.36	GO:0006814	sodium ion transport

0.84	GO:0015377	cation:chloride symporter activity
0.51	GO:0008519	ammonium transmembrane transporter activity
0.50	GO:0019901	protein kinase binding

0.49	GO:0098590	plasma membrane region
0.47	GO:0045177	apical part of cell
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P55014|S12A1_MOUSE
Solute carrier family 12 member 1
Search

SLC12A1

0.96	Solute carrier family 12 member 1, alternative spliced isoform

0.75	GO:1902476	chloride transmembrane transport
0.51	GO:0070634	transepithelial ammonium transport
0.50	GO:0030321	transepithelial chloride transport
0.47	GO:0072488	ammonium transmembrane transport
0.39	GO:0006814	sodium ion transport
0.38	GO:0006813	potassium ion transport
0.38	GO:0006972	hyperosmotic response
0.37	GO:0045795	positive regulation of cell volume
0.36	GO:0032502	developmental process
0.36	GO:0007214	gamma-aminobutyric acid signaling pathway

0.83	GO:0015377	cation:chloride symporter activity
0.47	GO:0008519	ammonium transmembrane transporter activity
0.46	GO:0019901	protein kinase binding
0.35	GO:0004170	dUTP diphosphatase activity

0.53	GO:0070062	extracellular exosome
0.48	GO:0016324	apical plasma membrane
0.34	GO:0016323	basolateral plasma membrane
0.33	GO:0005887	integral component of plasma membrane

0.35	EC:3.6.1.23	GO:0004170
0.35	KEGG:R02100	GO:0004170

sp|P55041|GEM_MOUSE
GTP-binding protein GEM
Search

GEM

0.46	GTP binding protein overexpressed in skeletal muscle

0.85	GO:1901841	regulation of high voltage-gated calcium channel activity
0.83	GO:1901386	negative regulation of voltage-gated calcium channel activity
0.61	GO:0007165	signal transduction
0.56	GO:0051310	metaphase plate congression
0.51	GO:0000278	mitotic cell cycle
0.47	GO:0051276	chromosome organization
0.35	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.34	GO:0006955	immune response

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0000287	magnesium ion binding
0.43	GO:0005246	calcium channel regulator activity
0.36	GO:0005516	calmodulin binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0005509	calcium ion binding

0.56	GO:0051233	spindle midzone
0.55	GO:0030496	midbody
0.54	GO:0072686	mitotic spindle
0.52	GO:0009898	cytoplasmic side of plasma membrane
0.45	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P55050|FABPI_MOUSE
Fatty acid-binding protein, intestinal
Search

FABP2

0.97	Intestinal fatty acid binding protein 2

0.36	GO:0007586	digestion
0.35	GO:0019433	triglyceride catabolic process
0.35	GO:0015909	long-chain fatty acid transport
0.34	GO:0003008	system process
0.34	GO:0006631	fatty acid metabolic process

0.85	GO:0005504	fatty acid binding
0.35	GO:0005324	long-chain fatty acid transporter activity
0.33	GO:0005515	protein binding

0.38	GO:0031526	brush border membrane
0.37	GO:0005622	intracellular
0.35	GO:0005902	microvillus
0.34	GO:0045177	apical part of cell
0.34	GO:0043227	membrane-bounded organelle

sp|P55065|PLTP_MOUSE
Phospholipid transfer protein
Search

PLTP

0.97	Lipid transfer protein II

0.62	GO:0010189	vitamin E biosynthetic process
0.62	GO:0006629	lipid metabolic process
0.62	GO:0010875	positive regulation of cholesterol efflux
0.62	GO:0035627	ceramide transport
0.61	GO:0034375	high-density lipoprotein particle remodeling
0.59	GO:0030317	flagellated sperm motility
0.56	GO:0015914	phospholipid transport
0.37	GO:0090108	positive regulation of high-density lipoprotein particle assembly

0.71	GO:0008289	lipid binding
0.63	GO:1904121	phosphatidylethanolamine transporter activity
0.63	GO:0035620	ceramide transporter activity
0.62	GO:0008525	phosphatidylcholine transporter activity
0.62	GO:1990050	phosphatidic acid transporter activity
0.61	GO:0050997	quaternary ammonium group binding
0.57	GO:0070405	ammonium ion binding
0.51	GO:0033218	amide binding
0.42	GO:0043168	anion binding

0.70	GO:0005615	extracellular space
0.59	GO:1990777	lipoprotein particle
0.30	GO:0016020	membrane

sp|P55066|NCAN_MOUSE
Neurocan core protein
Search

NCAN

0.92	Neurocan b

0.70	GO:0007155	cell adhesion
0.50	GO:0001501	skeletal system development
0.49	GO:0007417	central nervous system development
0.47	GO:0051823	regulation of synapse structural plasticity
0.38	GO:0030207	chondroitin sulfate catabolic process
0.38	GO:0030208	dermatan sulfate biosynthetic process
0.37	GO:0030206	chondroitin sulfate biosynthetic process
0.36	GO:0030198	extracellular matrix organization

0.82	GO:0005540	hyaluronic acid binding
0.69	GO:0005509	calcium ion binding
0.51	GO:0005201	extracellular matrix structural constituent
0.43	GO:0030246	carbohydrate binding

0.48	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0043202	lysosomal lumen
0.37	GO:0005796	Golgi lumen
0.37	GO:0005886	plasma membrane

sp|P55086|PAR2_MOUSE
Proteinase-activated receptor 2
Search

F2RL1

0.97	Protease-activated receptor 2

0.86	GO:0070493	thrombin-activated receptor signaling pathway
0.82	GO:0007596	blood coagulation
0.63	GO:0090195	chemokine secretion
0.63	GO:0035025	positive regulation of Rho protein signal transduction
0.63	GO:0097029	mature conventional dendritic cell differentiation
0.63	GO:1900135	positive regulation of renin secretion into blood stream
0.62	GO:0072643	interferon-gamma secretion
0.62	GO:0072608	interleukin-10 secretion
0.61	GO:0070963	positive regulation of neutrophil mediated killing of gram-negative bacterium
0.61	GO:0090198	negative regulation of chemokine secretion

0.86	GO:0015057	thrombin-activated receptor activity
0.61	GO:0031681	G-protein beta-subunit binding
0.59	GO:0001965	G-protein alpha-subunit binding
0.37	GO:0032795	heterotrimeric G-protein binding
0.36	GO:0005102	receptor binding
0.35	GO:0008233	peptidase activity
0.33	GO:0004435	phosphatidylinositol phospholipase C activity

0.60	GO:0031143	pseudopodium
0.54	GO:0005769	early endosome
0.50	GO:0005887	integral component of plasma membrane
0.40	GO:0016324	apical plasma membrane
0.37	GO:0043234	protein complex
0.36	GO:0031094	platelet dense tubular network
0.35	GO:0005901	caveola
0.35	GO:0005770	late endosome
0.35	GO:0009986	cell surface
0.34	GO:0005794	Golgi apparatus

0.35	EC:3.4	GO:0008233
0.33	KEGG:R03435	GO:0004435

sp|P55088|AQP4_MOUSE
Aquaporin-4
Search

AQP4

0.95	Aquaporin 4 transcript variant a

0.57	GO:0050891	multicellular organismal water homeostasis
0.57	GO:0071346	cellular response to interferon-gamma
0.55	GO:0055085	transmembrane transport
0.48	GO:0006833	water transport
0.39	GO:0006811	ion transport
0.38	GO:0003014	renal system process
0.36	GO:0007605	sensory perception of sound
0.36	GO:0060354	negative regulation of cell adhesion molecule production
0.36	GO:0015670	carbon dioxide transport
0.35	GO:0032691	negative regulation of interleukin-1 beta production

0.69	GO:0022803	passive transmembrane transporter activity
0.48	GO:0005372	water transmembrane transporter activity
0.37	GO:0042802	identical protein binding
0.34	GO:0008146	sulfotransferase activity

0.55	GO:0009897	external side of plasma membrane
0.46	GO:0016323	basolateral plasma membrane
0.41	GO:0005887	integral component of plasma membrane
0.39	GO:0005737	cytoplasm
0.36	GO:0005911	cell-cell junction
0.36	GO:0046930	pore complex
0.35	GO:0030315	T-tubule
0.35	GO:0045178	basal part of cell
0.35	GO:0031253	cell projection membrane
0.33	GO:0098588	bounding membrane of organelle

0.34

GO:0008146

sp|P55095|GLUC_MOUSE
Glucagon
Search

GCG

0.97	Preproglucagon B

0.76	GO:0010469	regulation of receptor activity
0.62	GO:0010737	protein kinase A signaling
0.61	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
0.61	GO:1900118	negative regulation of execution phase of apoptosis
0.60	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
0.60	GO:0090280	positive regulation of calcium ion import
0.60	GO:0051571	positive regulation of histone H3-K4 methylation
0.60	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.60	GO:0032099	negative regulation of appetite
0.58	GO:0033138	positive regulation of peptidyl-serine phosphorylation

0.79	GO:0005179	hormone activity
0.53	GO:0042802	identical protein binding
0.51	GO:0031769	glucagon receptor binding
0.37	GO:0017171	serine hydrolase activity
0.36	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.33	GO:0004386	helicase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.66	GO:0005576	extracellular region
0.40	GO:0005737	cytoplasm
0.39	GO:0031983	vesicle lumen
0.36	GO:0097708	intracellular vesicle
0.36	GO:0012505	endomembrane system
0.36	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005886	plasma membrane
0.33	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

sp|P55096|ABCD3_MOUSE
ATP-binding cassette sub-family D member 3
Search

ABCD3

0.96	LOW QUALITY PROTEIN: ATP-binding cassette sub-family D member 3

0.85	GO:0015910	peroxisomal long-chain fatty acid import
0.56	GO:0042760	very long-chain fatty acid catabolic process
0.54	GO:0055085	transmembrane transport
0.51	GO:0007031	peroxisome organization
0.50	GO:0006635	fatty acid beta-oxidation
0.47	GO:0006633	fatty acid biosynthetic process
0.37	GO:0014070	response to organic cyclic compound
0.36	GO:0042493	response to drug

0.82	GO:0005324	long-chain fatty acid transporter activity
0.73	GO:0042803	protein homodimerization activity
0.64	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0043621	protein self-association
0.33	GO:0005198	structural molecule activity

0.74	GO:0005777	peroxisome
0.54	GO:0031907	microbody lumen
0.51	GO:0031903	microbody membrane
0.44	GO:0031966	mitochondrial membrane
0.44	GO:0019866	organelle inner membrane
0.34	GO:0005829	cytosol
0.33	GO:0019028	viral capsid
0.30	GO:0016021	integral component of membrane

sp|P55097|CATK_MOUSE
Cathepsin K
Search

CTSK

0.93	Cathepsin K (Pycnodysostosis)

0.61	GO:0006508	proteolysis
0.60	GO:0030574	collagen catabolic process
0.56	GO:1903146	regulation of autophagy of mitochondrion
0.56	GO:1903955	positive regulation of protein targeting to mitochondrion
0.54	GO:0044257	cellular protein catabolic process
0.45	GO:0097067	cellular response to thyroid hormone stimulus
0.44	GO:0022617	extracellular matrix disassembly
0.43	GO:0002250	adaptive immune response
0.42	GO:0071711	basement membrane organization
0.42	GO:0009628	response to abiotic stimulus

0.72	GO:0008234	cysteine-type peptidase activity
0.61	GO:0001968	fibronectin binding
0.60	GO:0043394	proteoglycan binding
0.57	GO:0005518	collagen binding
0.50	GO:0004175	endopeptidase activity
0.42	GO:0043236	laminin binding
0.39	GO:0097655	serpin family protein binding
0.38	GO:0042393	histone binding
0.37	GO:0046983	protein dimerization activity
0.36	GO:0003700	DNA binding transcription factor activity

0.55	GO:0005615	extracellular space
0.52	GO:0005764	lysosome
0.48	GO:0005654	nucleoplasm
0.38	GO:0005667	transcription factor complex
0.38	GO:0031904	endosome lumen
0.37	GO:0005775	vacuolar lumen
0.34	GO:1904724	tertiary granule lumen
0.34	GO:1904813	ficolin-1-rich granule lumen
0.34	GO:0005730	nucleolus
0.33	GO:1903561	extracellular vesicle

0.72

GO:0008234

sp|P55098|PEX2_MOUSE
Peroxisome biogenesis factor 2
Search

PEX2

0.83	Peroxisomal biogenesis factor 2

0.59	GO:0048147	negative regulation of fibroblast proliferation
0.58	GO:0031648	protein destabilization
0.57	GO:0050680	negative regulation of epithelial cell proliferation
0.57	GO:0000038	very long-chain fatty acid metabolic process
0.56	GO:0016558	protein import into peroxisome matrix
0.53	GO:0000122	negative regulation of transcription by RNA polymerase II
0.53	GO:0006635	fatty acid beta-oxidation
0.38	GO:0045540	regulation of cholesterol biosynthetic process
0.38	GO:0006699	bile acid biosynthetic process
0.38	GO:0042632	cholesterol homeostasis

0.53	GO:0046872	metal ion binding
0.38	GO:0061630	ubiquitin protein ligase activity
0.35	GO:0016874	ligase activity
0.33	GO:0005515	protein binding
0.32	GO:0051538	3 iron, 4 sulfur cluster binding
0.32	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.32	GO:0051537	2 iron, 2 sulfur cluster binding
0.32	GO:0051539	4 iron, 4 sulfur cluster binding
0.31	GO:0009055	electron transfer activity

0.55	GO:0016593	Cdc73/Paf1 complex
0.55	GO:0005779	integral component of peroxisomal membrane
0.32	GO:0031966	mitochondrial membrane
0.32	GO:0019866	organelle inner membrane

0.35	EC:6	GO:0016874
0.32	KEGG:R02164	GO:0008177

sp|P55099|TKNK_MOUSE
Tachykinin-3
Search

TAC3

0.97	Neurokinin B

0.85	GO:0007217	tachykinin receptor signaling pathway
0.47	GO:0007218	neuropeptide signaling pathway
0.41	GO:0007018	microtubule-based movement
0.40	GO:0043278	response to morphine
0.40	GO:0045777	positive regulation of blood pressure
0.38	GO:1902093	positive regulation of flagellated sperm motility
0.38	GO:0007565	female pregnancy

0.41	GO:0003777	microtubule motor activity
0.41	GO:0008017	microtubule binding
0.41	GO:0003779	actin binding
0.40	GO:0031836	neuromedin K receptor binding
0.40	GO:0031837	substance K receptor binding
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005576	extracellular region
0.41	GO:0016459	myosin complex
0.39	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|P55104|INHBC_MOUSE
Inhibin beta C chain
Search

INHBC

0.96	Inhibin beta C subunit

0.74	GO:0010469	regulation of receptor activity
0.54	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.53	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.51	GO:0048468	cell development
0.51	GO:0042981	regulation of apoptotic process
0.50	GO:0043408	regulation of MAPK cascade
0.49	GO:0032686	negative regulation of hepatocyte growth factor production
0.49	GO:0048176	regulation of hepatocyte growth factor biosynthetic process
0.49	GO:0046882	negative regulation of follicle-stimulating hormone secretion
0.48	GO:0046881	positive regulation of follicle-stimulating hormone secretion

0.77	GO:0008083	growth factor activity
0.76	GO:0005179	hormone activity
0.53	GO:0005160	transforming growth factor beta receptor binding
0.51	GO:0005125	cytokine activity
0.43	GO:0042803	protein homodimerization activity
0.35	GO:0034711	inhibin binding
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0046812	host cell surface binding

0.65	GO:0005576	extracellular region
0.45	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0031982	vesicle
0.37	GO:0071944	cell periphery
0.32	GO:0043234	protein complex

sp|P55105|BMP8B_MOUSE
Bone morphogenetic protein 8B
Search

0.83	Bone morphogenetic protein 5

0.74	GO:0010469	regulation of receptor activity
0.57	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.57	GO:0060395	SMAD protein signal transduction
0.56	GO:0030509	BMP signaling pathway
0.53	GO:0043408	regulation of MAPK cascade
0.52	GO:0048468	cell development
0.51	GO:0042981	regulation of apoptotic process
0.46	GO:0002024	diet induced thermogenesis
0.46	GO:2000505	regulation of energy homeostasis
0.45	GO:0001503	ossification

0.77	GO:0008083	growth factor activity
0.59	GO:0070700	BMP receptor binding
0.56	GO:0005160	transforming growth factor beta receptor binding
0.53	GO:0005125	cytokine activity
0.36	GO:0008410	CoA-transferase activity
0.33	GO:0008017	microtubule binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0008201	heparin binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.65	GO:0005576	extracellular region
0.32	GO:0031982	vesicle
0.32	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.36

EC:2.8.3

GO:0008410

sp|P55144|TYRO3_MOUSE
Tyrosine-protein kinase receptor TYRO3
Search

TYRO3

0.95	Tyrosine-protein kinase receptor TYRO3

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.67	GO:0070050	neuron cellular homeostasis
0.66	GO:0060068	vagina development
0.66	GO:0001779	natural killer cell differentiation
0.66	GO:0034122	negative regulation of toll-like receptor signaling pathway
0.66	GO:0070527	platelet aggregation
0.66	GO:0043491	protein kinase B signaling
0.66	GO:0043277	apoptotic cell clearance
0.65	GO:0034446	substrate adhesion-dependent cell spreading
0.65	GO:0021885	forebrain cell migration

0.77	GO:0004713	protein tyrosine kinase activity
0.68	GO:0043548	phosphatidylinositol 3-kinase binding
0.56	GO:0046982	protein heterodimerization activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0019199	transmembrane receptor protein kinase activity
0.38	GO:0104005	hijacked molecular function
0.36	GO:0005057	signal transducer activity, downstream of receptor

0.50	GO:0005635	nuclear envelope
0.49	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.77

GO:0004713

sp|P55194|3BP1_MOUSE
SH3 domain-binding protein 1
Search

SH3BP1

0.97	SH3 domain-binding protein 1

0.75	GO:0043547	positive regulation of GTPase activity
0.64	GO:0045198	establishment of epithelial cell apical/basal polarity
0.62	GO:0006911	phagocytosis, engulfment
0.62	GO:0043535	regulation of blood vessel endothelial cell migration
0.61	GO:0051058	negative regulation of small GTPase mediated signal transduction
0.61	GO:0007165	signal transduction
0.60	GO:0034329	cell junction assembly
0.59	GO:0030834	regulation of actin filament depolymerization
0.57	GO:0016477	cell migration
0.55	GO:0007015	actin filament organization

0.76	GO:0005096	GTPase activator activity
0.65	GO:0030215	semaphorin receptor binding
0.41	GO:0017124	SH3 domain binding
0.38	GO:0016791	phosphatase activity

0.63	GO:0001891	phagocytic cup
0.60	GO:0030027	lamellipodium
0.59	GO:0005923	bicellular tight junction
0.58	GO:0005912	adherens junction
0.58	GO:0000145	exocyst
0.52	GO:0005829	cytosol
0.48	GO:0005634	nucleus

0.38

EC:3.1.3 EC:3.1.3.41

GO:0016791

sp|P55200|KMT2A_MOUSE
Histone-lysine N-methyltransferase 2A
Search

KMT2A

0.51	Histone-lysine N-methyltransferase

0.82	GO:0051568	histone H3-K4 methylation
0.66	GO:1901674	regulation of histone H3-K27 acetylation
0.64	GO:2001040	positive regulation of cellular response to drug
0.64	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.63	GO:0071440	regulation of histone H3-K14 acetylation
0.63	GO:0051571	positive regulation of histone H3-K4 methylation
0.63	GO:0043984	histone H4-K16 acetylation
0.63	GO:0035640	exploration behavior
0.63	GO:0060216	definitive hemopoiesis
0.62	GO:2000615	regulation of histone H3-K9 acetylation

0.84	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.63	GO:0045322	unmethylated CpG binding
0.61	GO:0070577	lysine-acetylated histone binding
0.61	GO:0008270	zinc ion binding
0.60	GO:0001046	core promoter sequence-specific DNA binding
0.56	GO:0003682	chromatin binding
0.56	GO:0042803	protein homodimerization activity
0.37	GO:0003680	AT DNA binding
0.35	GO:0034450	ubiquitin-ubiquitin ligase activity
0.34	GO:0015078	hydrogen ion transmembrane transporter activity

0.82	GO:0071339	MLL1 complex
0.52	GO:0005829	cytosol
0.36	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.35	GO:0000151	ubiquitin ligase complex

sp|P55249|LX12E_MOUSE
Arachidonate 12-lipoxygenase, epidermal-type
Search

ALOX15

0.93	Arachidonate lipoxygenase, epidermal

0.64	GO:0019372	lipoxygenase pathway
0.61	GO:0019369	arachidonic acid metabolic process
0.59	GO:0046456	icosanoid biosynthetic process
0.58	GO:2001300	lipoxin metabolic process
0.55	GO:0006691	leukotriene metabolic process
0.55	GO:0042759	long-chain fatty acid biosynthetic process
0.53	GO:0006636	unsaturated fatty acid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0030155	regulation of cell adhesion
0.51	GO:0035963	cellular response to interleukin-13

0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.63	GO:0005506	iron ion binding
0.48	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.44	GO:0047977	hepoxilin-epoxide hydrolase activity
0.41	GO:0051120	hepoxilin A3 synthase activity
0.36	GO:0097260	eoxin A4 synthase activity
0.35	GO:0005515	protein binding
0.35	GO:0019870	potassium channel inhibitor activity
0.33	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
0.32	GO:0004984	olfactory receptor activity

0.51	GO:0005829	cytosol
0.48	GO:0042383	sarcolemma
0.47	GO:0005811	lipid droplet
0.47	GO:0005641	nuclear envelope lumen
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.46	GO:0016363	nuclear matrix
0.44	GO:0031965	nuclear membrane
0.41	GO:0005654	nucleoplasm
0.36	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle

0.75

EC:1.13.11

GO:0016702

sp|P55258|RAB8A_MOUSE
Ras-related protein Rab-8A
Search

RAB8A

0.92	Oncogene c-mel

0.57	GO:0048210	Golgi vesicle fusion to target membrane
0.54	GO:0006904	vesicle docking involved in exocytosis
0.52	GO:0060271	cilium assembly
0.50	GO:0010506	regulation of autophagy
0.50	GO:0072659	protein localization to plasma membrane
0.48	GO:0017157	regulation of exocytosis
0.45	GO:0048666	neuron development
0.44	GO:0009306	protein secretion
0.43	GO:0032402	melanosome transport
0.43	GO:0032869	cellular response to insulin stimulus

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.56	GO:0031489	myosin V binding
0.55	GO:0019003	GDP binding
0.40	GO:0017137	Rab GTPase binding
0.38	GO:0019901	protein kinase binding
0.36	GO:0071532	ankyrin repeat binding
0.36	GO:0032794	GTPase activating protein binding
0.35	GO:0030911	TPR domain binding
0.35	GO:0005102	receptor binding

0.56	GO:0055038	recycling endosome membrane
0.54	GO:0045335	phagocytic vesicle
0.54	GO:0097546	ciliary base
0.53	GO:0097730	non-motile cilium
0.53	GO:0030133	transport vesicle
0.52	GO:0036064	ciliary basal body
0.51	GO:0005813	centrosome
0.50	GO:0030136	clathrin-coated vesicle
0.49	GO:0005798	Golgi-associated vesicle
0.48	GO:0030667	secretory granule membrane

sp|P55264|ADK_MOUSE
Adenosine kinase
Search

ADK

0.62	Adenosine kinase a

0.75	GO:0006166	purine ribonucleoside salvage
0.73	GO:0006167	AMP biosynthetic process
0.58	GO:0006175	dATP biosynthetic process
0.53	GO:0016310	phosphorylation
0.49	GO:0046086	adenosine biosynthetic process
0.41	GO:0044262	cellular carbohydrate metabolic process
0.38	GO:0032261	purine nucleotide salvage
0.36	GO:0044342	type B pancreatic cell proliferation
0.35	GO:0010613	positive regulation of cardiac muscle hypertrophy
0.35	GO:0032922	circadian regulation of gene expression

0.84	GO:0004001	adenosine kinase activity
0.43	GO:0019200	carbohydrate kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046872	metal ion binding
0.34	GO:0003723	RNA binding

0.48	GO:0005829	cytosol
0.47	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.84

EC:2.7.1.20

GO:0004001

sp|P55271|CDN2B_MOUSE
Cyclin-dependent kinase 4 inhibitor B
Search

0.97	Cyclin dependant kinase inhibitor

0.67	GO:0007050	cell cycle arrest
0.66	GO:0044772	mitotic cell cycle phase transition
0.66	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.65	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
0.65	GO:0030219	megakaryocyte differentiation
0.65	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.64	GO:0008285	negative regulation of cell proliferation
0.63	GO:0044839	cell cycle G2/M phase transition
0.62	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.62	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway

0.68	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.63	GO:0019901	protein kinase binding
0.53	GO:0016301	kinase activity
0.51	GO:0051059	NF-kappaB binding
0.39	GO:1990948	ubiquitin ligase inhibitor activity
0.39	GO:0097371	MDM2/MDM4 family protein binding
0.38	GO:0097718	disordered domain specific binding
0.38	GO:0047485	protein N-terminus binding
0.38	GO:0002039	p53 binding
0.38	GO:0019789	SUMO transferase activity

0.53	GO:0035985	senescence-associated heterochromatin focus
0.52	GO:0005634	nucleus
0.43	GO:0005737	cytoplasm
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0004222

sp|P55284|CADH5_MOUSE
Cadherin-5
Search

CDH5

0.93	Cadherin 5, type 2 preproprotein variant (Fragment)

0.85	GO:0001955	blood vessel maturation
0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.62	GO:1901552	positive regulation of endothelial cell development
0.61	GO:1903140	regulation of establishment of endothelial barrier
0.58	GO:0050728	negative regulation of inflammatory response
0.58	GO:0007043	cell-cell junction assembly
0.57	GO:0045765	regulation of angiogenesis
0.57	GO:0007179	transforming growth factor beta receptor signaling pathway
0.57	GO:1904018	positive regulation of vasculature development
0.55	GO:2000114	regulation of establishment of cell polarity

0.70	GO:0005509	calcium ion binding
0.58	GO:0044325	ion channel binding
0.57	GO:0008013	beta-catenin binding
0.56	GO:0019903	protein phosphatase binding
0.52	GO:0005102	receptor binding
0.33	GO:0005003	ephrin receptor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.57	GO:0005913	cell-cell adherens junction
0.55	GO:0009897	external side of plasma membrane
0.55	GO:0005923	bicellular tight junction
0.31	GO:0005887	integral component of plasma membrane

sp|P55288|CAD11_MOUSE
Cadherin-11
Search

CDH11

0.97	Osteoblast cadherin

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.56	GO:0021957	corticospinal tract morphogenesis
0.42	GO:0048840	otolith development
0.42	GO:0031290	retinal ganglion cell axon guidance
0.41	GO:0060041	retina development in camera-type eye
0.38	GO:0035249	synaptic transmission, glutamatergic
0.37	GO:0009409	response to cold
0.35	GO:0034332	adherens junction organization
0.35	GO:0030199	collagen fibril organization
0.35	GO:0001503	ossification

0.70	GO:0005509	calcium ion binding
0.36	GO:0042802	identical protein binding
0.35	GO:0008013	beta-catenin binding
0.33	GO:0046983	protein dimerization activity

0.55	GO:0005886	plasma membrane
0.38	GO:0043083	synaptic cleft
0.38	GO:0005737	cytoplasm
0.38	GO:0043679	axon terminus
0.36	GO:0070062	extracellular exosome
0.34	GO:0005911	cell-cell junction
0.30	GO:0016021	integral component of membrane

sp|P55292|DSC2_MOUSE
Desmocollin-2
Search

DSC2

0.97	Desmocollin-2

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.57	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication
0.56	GO:0098911	regulation of ventricular cardiac muscle cell action potential
0.55	GO:0086091	regulation of heart rate by cardiac conduction
0.51	GO:0009267	cellular response to starvation
0.38	GO:0070268	cornification
0.38	GO:0050821	protein stabilization
0.37	GO:0001701	in utero embryonic development
0.34	GO:0043312	neutrophil degranulation
0.34	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

0.70	GO:0005509	calcium ion binding
0.39	GO:0045295	gamma-catenin binding
0.36	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication

0.58	GO:0030057	desmosome
0.56	GO:0005886	plasma membrane
0.55	GO:0014704	intercalated disc
0.53	GO:0005913	cell-cell adherens junction
0.49	GO:0031410	cytoplasmic vesicle
0.40	GO:0070062	extracellular exosome
0.34	GO:0005921	gap junction
0.33	GO:0012506	vesicle membrane
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle

sp|P55302|AMRP_MOUSE
Alpha-2-macroglobulin receptor-associated protein
Search

LRPAP1

0.94	Low density lipoprotein receptor-associated protein 1

0.86	GO:1900116	extracellular negative regulation of signal transduction
0.58	GO:1900222	negative regulation of amyloid-beta clearance
0.58	GO:0010916	negative regulation of very-low-density lipoprotein particle clearance
0.58	GO:0002091	negative regulation of receptor internalization
0.56	GO:0045056	transcytosis
0.54	GO:0032091	negative regulation of protein binding
0.51	GO:0060548	negative regulation of cell death
0.36	GO:1900223	positive regulation of amyloid-beta clearance

0.86	GO:0048019	receptor antagonist activity
0.86	GO:0050750	low-density lipoprotein particle receptor binding
0.83	GO:0008201	heparin binding
0.58	GO:0070326	very-low-density lipoprotein particle receptor binding
0.42	GO:0035473	lipase binding
0.35	GO:0001540	amyloid-beta binding

0.70	GO:0005783	endoplasmic reticulum
0.66	GO:0005576	extracellular region
0.54	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.53	GO:0005801	cis-Golgi network
0.50	GO:0005768	endosome
0.49	GO:0005794	Golgi apparatus
0.47	GO:0043233	organelle lumen
0.42	GO:0044446	intracellular organelle part
0.42	GO:0005886	plasma membrane
0.38	GO:0009986	cell surface

sp|P55772|ENTP1_MOUSE
Ectonucleoside triphosphate diphosphohydrolase 1
Search

ENTPD1

0.94	Ectonucleoside triphosphate diphosphohydrolase 1

0.40	GO:0071405	cellular response to methanol
0.39	GO:0009137	purine nucleoside diphosphate catabolic process
0.39	GO:0045471	response to ethanol
0.39	GO:0009191	ribonucleoside diphosphate catabolic process
0.38	GO:0007596	blood coagulation
0.38	GO:0010038	response to metal ion
0.37	GO:0010238	response to proline
0.37	GO:0001775	cell activation
0.37	GO:0033602	negative regulation of dopamine secretion
0.36	GO:1903576	response to L-arginine

0.51	GO:0016787	hydrolase activity
0.36	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.38	GO:0005605	basal lamina
0.37	GO:0070062	extracellular exosome
0.35	GO:0014069	postsynaptic density
0.35	GO:0016323	basolateral plasma membrane
0.35	GO:0008021	synaptic vesicle
0.35	GO:0043025	neuronal cell body
0.35	GO:0097060	synaptic membrane
0.35	GO:0043005	neuron projection
0.35	GO:0009986	cell surface
0.33	GO:0005887	integral component of plasma membrane

0.51

GO:0016787

sp|P55821|STMN2_MOUSE
Stathmin-2
Search

STMN2

0.85

Stathmin

0.84	GO:0031110	regulation of microtubule polymerization or depolymerization
0.57	GO:0048699	generation of neurons
0.55	GO:1990090	cellular response to nerve growth factor stimulus
0.53	GO:0032272	negative regulation of protein polymerization
0.53	GO:1901881	positive regulation of protein depolymerization
0.53	GO:1902904	negative regulation of supramolecular fiber organization
0.53	GO:0120036	plasma membrane bounded cell projection organization
0.52	GO:0051494	negative regulation of cytoskeleton organization
0.52	GO:0000226	microtubule cytoskeleton organization
0.52	GO:0048468	cell development

0.53	GO:0048306	calcium-dependent protein binding
0.52	GO:0015631	tubulin binding
0.37	GO:0019904	protein domain specific binding
0.35	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity
0.32	GO:0004871	signal transducer activity

0.54	GO:0030426	growth cone
0.52	GO:0030027	lamellipodium
0.51	GO:0043025	neuronal cell body
0.50	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0030424	axon
0.37	GO:0031982	vesicle
0.37	GO:0005794	Golgi apparatus
0.36	GO:0005829	cytosol
0.36	GO:0005874	microtubule
0.33	GO:0043230	extracellular organelle

0.35

EC:3.1.1.47

GO:0003847

sp|P55849|DSC1_MOUSE
Desmocollin-1
Search

DSC1

0.95	Desmosomal glycoprotein 2/3

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.52	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication
0.51	GO:0098911	regulation of ventricular cardiac muscle cell action potential
0.50	GO:0086091	regulation of heart rate by cardiac conduction
0.47	GO:0009267	cellular response to starvation
0.38	GO:0070268	cornification
0.37	GO:0050821	protein stabilization
0.36	GO:0001701	in utero embryonic development
0.36	GO:0043312	neutrophil degranulation
0.35	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

0.70	GO:0005509	calcium ion binding
0.39	GO:0045295	gamma-catenin binding
0.35	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication

0.56	GO:0005886	plasma membrane
0.54	GO:0030057	desmosome
0.50	GO:0014704	intercalated disc
0.49	GO:0005913	cell-cell adherens junction
0.46	GO:0031982	vesicle
0.40	GO:0043230	extracellular organelle
0.39	GO:0044444	cytoplasmic part
0.38	GO:0043229	intracellular organelle
0.38	GO:0005615	extracellular space
0.35	GO:0005921	gap junction

sp|P55850|DSC3_MOUSE
Desmocollin-3
Search

DSC3

0.97	Desmocollin-3

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.53	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication
0.52	GO:0098911	regulation of ventricular cardiac muscle cell action potential
0.52	GO:0086091	regulation of heart rate by cardiac conduction
0.48	GO:0009267	cellular response to starvation
0.39	GO:0050821	protein stabilization
0.39	GO:0001701	in utero embryonic development
0.39	GO:0070268	cornification
0.34	GO:0043312	neutrophil degranulation
0.34	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

0.70	GO:0005509	calcium ion binding
0.42	GO:0045295	gamma-catenin binding
0.36	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication

0.56	GO:0030054	cell junction
0.56	GO:0005886	plasma membrane
0.46	GO:0031982	vesicle
0.40	GO:0044444	cytoplasmic part
0.39	GO:0043230	extracellular organelle
0.39	GO:0043229	intracellular organelle
0.38	GO:0005615	extracellular space
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0012505	endomembrane system

sp|P55937|GOGA3_MOUSE
Golgin subfamily A member 3
Search

GOLGA3

0.96	Golgin subfamily A member 3-lik

0.79	GO:0007283	spermatogenesis
0.36	GO:0006891	intra-Golgi vesicle-mediated transport
0.35	GO:0030154	cell differentiation
0.35	GO:0007275	multicellular organism development

0.57	GO:0045296	cadherin binding
0.33	GO:0005215	transporter activity

0.86	GO:0090498	extrinsic component of Golgi membrane
0.57	GO:0017119	Golgi transport complex
0.52	GO:0005730	nucleolus
0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.39	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.38	GO:0032580	Golgi cisterna membrane

sp|P56135|ATPK_MOUSE
ATP synthase subunit f, mitochondrial
Search

ATP5J2

0.93	ATP synthase membrane subunit f

0.42	GO:0006754	ATP biosynthetic process
0.40	GO:0015992	proton transport
0.37	GO:0042407	cristae formation
0.36	GO:0006839	mitochondrial transport
0.35	GO:0046907	intracellular transport
0.34	GO:0098662	inorganic cation transmembrane transport
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.42	GO:0016887	ATPase activity
0.33	GO:0022857	transmembrane transporter activity
0.33	GO:0003676	nucleic acid binding

0.50	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.43	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.39	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.42

GO:0016887

sp|P56183|RRP1_MOUSE
Ribosomal RNA processing protein 1 homolog A
Search

RRP1

0.82	Ribosomal RNA processing protein 1 homolog A

0.69	GO:0006364	rRNA processing
0.63	GO:0043923	positive regulation by host of viral transcription
0.60	GO:0098586	cellular response to virus
0.58	GO:0010923	negative regulation of phosphatase activity
0.56	GO:0043065	positive regulation of apoptotic process
0.55	GO:0006366	transcription by RNA polymerase II
0.54	GO:0045944	positive regulation of transcription by RNA polymerase II
0.53	GO:0034260	negative regulation of GTPase activity
0.50	GO:0043484	regulation of RNA splicing

0.61

GO:0001105

RNA polymerase II transcription coactivator activity

0.83	GO:0030688	preribosome, small subunit precursor
0.64	GO:0005730	nucleolus
0.58	GO:0030687	preribosome, large subunit precursor
0.51	GO:0000791	euchromatin
0.50	GO:0000792	heterochromatin

sp|P56198|CIDEC_MOUSE
Cell death activator CIDE-3
Search

CIDEC

0.95	Cell death inducing DFFA like effector c

0.78	GO:0006915	apoptotic process
0.57	GO:0019915	lipid storage
0.55	GO:0050995	negative regulation of lipid catabolic process
0.55	GO:0042981	regulation of apoptotic process
0.55	GO:0035634	response to stilbenoid
0.55	GO:1903624	regulation of DNA catabolic process
0.54	GO:0010890	positive regulation of sequestering of triglyceride
0.54	GO:0032720	negative regulation of tumor necrosis factor production
0.54	GO:0050710	negative regulation of cytokine secretion
0.53	GO:0001659	temperature homeostasis

0.48

GO:0042803

protein homodimerization activity

0.63	GO:0005811	lipid droplet
0.43	GO:0005740	mitochondrial envelope
0.42	GO:0005634	nucleus

sp|P56203|CATW_MOUSE
Cathepsin W
Search

CTSW

0.92	Cathepsin W

0.61	GO:0006508	proteolysis
0.49	GO:0044257	cellular protein catabolic process
0.37	GO:0002576	platelet degranulation
0.36	GO:0006955	immune response
0.35	GO:0050790	regulation of catalytic activity
0.34	GO:0034769	basement membrane disassembly
0.33	GO:0019882	antigen processing and presentation
0.32	GO:0045861	negative regulation of proteolysis
0.32	GO:0006898	receptor-mediated endocytosis
0.32	GO:0044092	negative regulation of molecular function

0.72	GO:0008234	cysteine-type peptidase activity
0.46	GO:0004175	endopeptidase activity
0.33	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.33	GO:0030246	carbohydrate binding
0.32	GO:0005044	scavenger receptor activity
0.32	GO:0001871	pattern binding

0.52	GO:0005764	lysosome
0.49	GO:0005615	extracellular space
0.38	GO:0031089	platelet dense granule lumen
0.34	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

0.72

GO:0008234

sp|P56212|ARP19_MOUSE
cAMP-regulated phosphoprotein 19
Search

ARPP19

0.93	LOW QUALITY PROTEIN: cAMP-regulated phosphoprotein 19

0.83	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.67	GO:0051301	cell division
0.67	GO:0007049	cell cycle
0.41	GO:0050796	regulation of insulin secretion
0.39	GO:0045722	positive regulation of gluconeogenesis
0.36	GO:0046579	positive regulation of Ras protein signal transduction
0.36	GO:0007212	dopamine receptor signaling pathway
0.35	GO:0009749	response to glucose
0.35	GO:0046326	positive regulation of glucose import
0.33	GO:0007018	microtubule-based movement

0.83	GO:0004864	protein phosphatase inhibitor activity
0.46	GO:0051721	protein phosphatase 2A binding
0.45	GO:0015459	potassium channel regulator activity
0.41	GO:0008200	ion channel inhibitor activity
0.41	GO:0005102	receptor binding
0.34	GO:0019901	protein kinase binding
0.33	GO:0051015	actin filament binding
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.32	GO:0032559	adenyl ribonucleotide binding

0.49	GO:0005737	cytoplasm
0.35	GO:0005654	nucleoplasm
0.33	GO:0016459	myosin complex
0.30	GO:0031224	intrinsic component of membrane

sp|P56213|ALR_MOUSE
FAD-linked sulfhydryl oxidase ALR
Search

GFER

0.61	FAD-linked sulfhydryl oxidase ALR

0.52	GO:0055114	oxidation-reduction process
0.51	GO:0001889	liver development
0.41	GO:0007507	heart development
0.38	GO:0010469	regulation of receptor activity
0.37	GO:0072717	cellular response to actinomycin D
0.37	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity
0.36	GO:1903204	negative regulation of oxidative stress-induced neuron death
0.36	GO:0031100	animal organ regeneration
0.36	GO:2000573	positive regulation of DNA biosynthetic process
0.36	GO:0071356	cellular response to tumor necrosis factor

0.84	GO:0016972	thiol oxidase activity
0.50	GO:0015035	protein disulfide oxidoreductase activity
0.47	GO:0050660	flavin adenine dinucleotide binding
0.40	GO:0042803	protein homodimerization activity
0.38	GO:0008083	growth factor activity

0.47	GO:0005829	cytosol
0.46	GO:0005739	mitochondrion
0.39	GO:0031970	organelle envelope lumen
0.36	GO:0005576	extracellular region
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.84

EC:1.8.3.2

GO:0016972

sp|P56280|TCL1A_MOUSE
T-cell leukemia/lymphoma protein 1A
Search

MTCP1

0.97	Mature T-cell proliferation 1

0.85	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.80	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.68	GO:0010918	positive regulation of mitochondrial membrane potential
0.67	GO:0032461	positive regulation of protein oligomerization
0.66	GO:0070207	protein homotrimerization
0.63	GO:0071356	cellular response to tumor necrosis factor
0.60	GO:0008284	positive regulation of cell proliferation
0.60	GO:0043066	negative regulation of apoptotic process
0.49	GO:2000036	regulation of stem cell population maintenance
0.47	GO:0019827	stem cell population maintenance

0.85	GO:0043539	protein serine/threonine kinase activator activity
0.78	GO:0019901	protein kinase binding
0.57	GO:0042802	identical protein binding

0.60	GO:0043234	protein complex
0.54	GO:0005739	mitochondrion
0.49	GO:0045120	pronucleus
0.45	GO:0005938	cell cortex
0.42	GO:0005783	endoplasmic reticulum
0.38	GO:0031970	organelle envelope lumen

sp|P56371|RAB4A_MOUSE
Ras-related protein Rab-4A
Search

RAB4A

0.97	RAB4A, member RAS oncogene family variant (Fragment)

0.61	GO:0030100	regulation of endocytosis
0.55	GO:0019882	antigen processing and presentation
0.49	GO:0015031	protein transport
0.48	GO:0001944	vasculature development
0.38	GO:0032482	Rab protein signal transduction
0.37	GO:0032781	positive regulation of ATPase activity

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0008565	protein transporter activity
0.38	GO:0035255	ionotropic glutamate receptor binding
0.37	GO:0051117	ATPase binding
0.37	GO:0019905	syntaxin binding
0.37	GO:0001671	ATPase activator activity

0.58	GO:0070062	extracellular exosome
0.57	GO:0005768	endosome
0.57	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0032593	insulin-responsive compartment
0.36	GO:0098794	postsynapse
0.35	GO:0005829	cytosol
0.35	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P56375|ACYP2_MOUSE
Acylphosphatase-2
Search

ACYP2

0.51	Acylphosphatase

0.45	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.45	GO:0018108	peptidyl-tyrosine phosphorylation
0.35	GO:0046944	protein carbamoylation
0.34	GO:0051693	actin filament capping
0.33	GO:1901642	nucleoside transmembrane transport
0.33	GO:0007010	cytoskeleton organization

0.80	GO:0003998	acylphosphatase activity
0.46	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0042802	identical protein binding
0.34	GO:0003725	double-stranded RNA binding
0.34	GO:0016743	carboxyl- or carbamoyltransferase activity
0.34	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0005543	phospholipid binding

0.42	GO:0005739	mitochondrion
0.34	GO:0008091	spectrin
0.33	GO:0005887	integral component of plasma membrane

0.80

EC:3.6.1.7

GO:0003998

sp|P56376|ACYP1_MOUSE
Acylphosphatase-1
Search

ACYP1

0.54	Acylphosphatase

0.36	GO:0007131	reciprocal meiotic recombination
0.36	GO:0006298	mismatch repair
0.33	GO:0007144	female meiosis I
0.33	GO:0006796	phosphate-containing compound metabolic process
0.33	GO:0007130	synaptonemal complex assembly
0.33	GO:0007140	male meiotic nuclear division
0.33	GO:0010469	regulation of receptor activity
0.32	GO:0008104	protein localization
0.32	GO:0036211	protein modification process
0.32	GO:0044267	cellular protein metabolic process

0.80	GO:0003998	acylphosphatase activity
0.35	GO:0030983	mismatched DNA binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0019237	centromeric DNA binding
0.33	GO:0008083	growth factor activity
0.33	GO:0003682	chromatin binding
0.32	GO:0016301	kinase activity
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.36	GO:0070062	extracellular exosome
0.36	GO:0032300	mismatch repair complex
0.33	GO:0005712	chiasma
0.33	GO:0001673	male germ cell nucleus
0.33	GO:0000795	synaptonemal complex
0.30	GO:0016020	membrane

0.80

EC:3.6.1.7

GO:0003998

sp|P56379|68MP_MOUSE
6.8 kDa mitochondrial proteolipid
Search

0.97	Mitochondrial proteolipid

0.36	GO:0006915	apoptotic process
0.36	GO:0045786	negative regulation of cell cycle

0.35

GO:0008134

transcription factor binding

0.61	GO:0005739	mitochondrion
0.40	GO:0045259	proton-transporting ATP synthase complex
0.38	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P56380|AP4A_MOUSE
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
Search

NUDT2

0.76	Nucleoside diphosphate-linked moiety X motif 2

0.39	GO:0015967	diadenosine tetraphosphate catabolic process
0.38	GO:0006915	apoptotic process
0.37	GO:0006172	ADP biosynthetic process
0.36	GO:0006167	AMP biosynthetic process
0.35	GO:0006754	ATP biosynthetic process
0.34	GO:0034599	cellular response to oxidative stress
0.33	GO:0006030	chitin metabolic process
0.33	GO:0010951	negative regulation of endopeptidase activity

0.82	GO:0008796	bis(5'-nucleosyl)-tetraphosphatase activity
0.39	GO:0043135	5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity
0.37	GO:0032550	purine ribonucleoside binding
0.37	GO:0032561	guanyl ribonucleotide binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding
0.33	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0008061	chitin binding
0.32	GO:0032559	adenyl ribonucleotide binding

0.44	GO:0005739	mitochondrion
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005576	extracellular region

0.82

EC:3.6.1

GO:0008796

sp|P56382|ATP5E_MOUSE
ATP synthase subunit epsilon, mitochondrial
Search

ATP5E

0.88	ATP synthase subunit epsilonserine-threonine

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.38	GO:0042407	cristae formation
0.37	GO:0006839	mitochondrial transport
0.35	GO:0046907	intracellular transport

0.72	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.38	GO:0008553	proton-exporting ATPase activity, phosphorylative mechanism

0.84	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)
0.36	GO:0005759	mitochondrial matrix

0.38

EC:3.6.3.6

GO:0008553

sp|P56383|AT5G2_MOUSE
ATP synthase F(0) complex subunit C2, mitochondrial
Search

0.88	ATP synthase lipid-binding protein, mitochondrial

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.38	GO:0045471	response to ethanol
0.36	GO:0042407	cristae formation
0.35	GO:0006839	mitochondrial transport
0.34	GO:0046907	intracellular transport
0.34	GO:0007568	aging
0.33	GO:0055114	oxidation-reduction process

0.71	GO:0008289	lipid binding
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.45	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.45	GO:0019829	cation-transporting ATPase activity
0.35	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.35	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.33	GO:0005515	protein binding

0.72	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.48	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.34	GO:0005741	mitochondrial outer membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:1.1.1.42

GO:0004450

sp|P56384|AT5G3_MOUSE
ATP synthase F(0) complex subunit C3, mitochondrial
Search

0.85	ATP synthase lipid-binding protein, mitochondrial

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.38	GO:0045471	response to ethanol
0.36	GO:0042407	cristae formation
0.35	GO:0006839	mitochondrial transport
0.34	GO:0007568	aging
0.34	GO:0046907	intracellular transport
0.33	GO:0055114	oxidation-reduction process

0.71	GO:0008289	lipid binding
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.45	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.45	GO:0019829	cation-transporting ATPase activity
0.35	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.35	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.33	GO:0005515	protein binding

0.72	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.48	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.34	GO:0005741	mitochondrial outer membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:1.1.1.42

GO:0004450

sp|P56386|DEFB1_MOUSE
Beta-defensin 1
Search

DEFB1

0.81	Beta-defensin 1

0.81	GO:0033574	response to testosterone
0.78	GO:0002526	acute inflammatory response
0.74	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.71	GO:0045087	innate immune response
0.70	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.70	GO:0009617	response to bacterium
0.67	GO:0019933	cAMP-mediated signaling
0.61	GO:0098542	defense response to other organism
0.58	GO:0002385	mucosal immune response
0.58	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide

0.74	GO:0031731	CCR6 chemokine receptor binding
0.60	GO:0042802	identical protein binding

0.74	GO:1990742	microvesicle
0.70	GO:0097225	sperm midpiece
0.61	GO:0019898	extrinsic component of membrane
0.60	GO:0005615	extracellular space
0.40	GO:0005622	intracellular

sp|P56387|DYLT3_MOUSE
Dynein light chain Tctex-type 3
Search

DYNLT3

0.94	Dynein light chain Tctex-type 3

0.62	GO:0019060	intracellular transport of viral protein in host cell
0.49	GO:0007346	regulation of mitotic cell cycle
0.45	GO:0045787	positive regulation of cell cycle
0.45	GO:0051301	cell division
0.45	GO:0007049	cell cycle
0.41	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.41	GO:0050768	negative regulation of neurogenesis
0.41	GO:1905709	negative regulation of membrane permeability
0.41	GO:0030010	establishment of cell polarity
0.41	GO:0035022	positive regulation of Rac protein signal transduction

0.72	GO:0042802	identical protein binding
0.47	GO:0003774	motor activity
0.39	GO:0008022	protein C-terminus binding

0.82	GO:0005868	cytoplasmic dynein complex
0.70	GO:0000776	kinetochore
0.63	GO:0005881	cytoplasmic microtubule
0.56	GO:0099503	secretory vesicle
0.48	GO:0005818	aster
0.48	GO:0044217	other organism part
0.48	GO:0018995	host
0.47	GO:0000779	condensed chromosome, centromeric region
0.46	GO:0005876	spindle microtubule
0.46	GO:0072686	mitotic spindle

sp|P56388|CART_MOUSE
Cocaine- and amphetamine-regulated transcript protein
Search

CARTPT

0.97	Cocaine-and amphetamine-regulated transcript

0.86	GO:0032099	negative regulation of appetite
0.86	GO:0008343	adult feeding behavior
0.84	GO:0000186	activation of MAPKK activity
0.82	GO:0001678	cellular glucose homeostasis
0.78	GO:0009267	cellular response to starvation
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.65	GO:0032812	positive regulation of epinephrine secretion
0.63	GO:0051971	positive regulation of transmission of nerve impulse
0.62	GO:0045779	negative regulation of bone resorption
0.61	GO:0045777	positive regulation of blood pressure

0.50

GO:0005184

neuropeptide hormone activity

0.73	GO:0005615	extracellular space
0.57	GO:0030141	secretory granule
0.30	GO:0016020	membrane

sp|P56389|CDD_MOUSE
Cytidine deaminase
Search

CDA

0.49	Cytidine deaminase

0.79	GO:0009972	cytidine deamination
0.56	GO:0045980	negative regulation of nucleotide metabolic process
0.55	GO:0051289	protein homotetramerization
0.55	GO:0030308	negative regulation of cell growth
0.37	GO:0071217	cellular response to external biotic stimulus
0.36	GO:0046898	response to cycloheximide
0.36	GO:0019858	cytosine metabolic process
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0043097	pyrimidine nucleoside salvage
0.34	GO:0007166	cell surface receptor signaling pathway

0.79	GO:0004126	cytidine deaminase activity
0.62	GO:0008270	zinc ion binding
0.51	GO:0042803	protein homodimerization activity
0.46	GO:0001882	nucleoside binding

0.42	GO:0005829	cytosol
0.36	GO:1904724	tertiary granule lumen
0.36	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.34	GO:0005576	extracellular region

0.79

EC:3.5.4.5

GO:0004126

sp|P56390|CKS2_MOUSE
Cyclin-dependent kinases regulatory subunit 2
Search

CKS2

0.68	Cyclin-dependent kinases regulatory subunit

0.76	GO:0045859	regulation of protein kinase activity
0.67	GO:0051301	cell division
0.67	GO:0007049	cell cycle
0.53	GO:0008283	cell proliferation
0.49	GO:0045787	positive regulation of cell cycle
0.49	GO:0016310	phosphorylation
0.49	GO:0033674	positive regulation of kinase activity
0.48	GO:0001934	positive regulation of protein phosphorylation
0.48	GO:0007346	regulation of mitotic cell cycle
0.47	GO:0045893	positive regulation of transcription, DNA-templated

0.82	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.51	GO:0043539	protein serine/threonine kinase activator activity
0.51	GO:0016301	kinase activity
0.50	GO:0043130	ubiquitin binding
0.49	GO:0042393	histone binding
0.49	GO:0019901	protein kinase binding
0.47	GO:0003682	chromatin binding

0.51	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.51	GO:0019005	SCF ubiquitin ligase complex
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.82

GO:0016538

sp|P56391|CX6B1_MOUSE
Cytochrome c oxidase subunit 6B1
Search

COX6B1

0.74	Cytochrome c oxidase subunit

0.39	GO:0021762	substantia nigra development
0.35	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen
0.35	GO:0033617	mitochondrial respiratory chain complex IV assembly
0.35	GO:1902600	hydrogen ion transmembrane transport
0.34	GO:0034968	histone lysine methylation
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.35	GO:0015002	heme-copper terminal oxidase activity
0.35	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.35	GO:0015078	hydrogen ion transmembrane transporter activity
0.34	GO:0009055	electron transfer activity
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0018024	histone-lysine N-methyltransferase activity
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0008270	zinc ion binding

0.61	GO:0005739	mitochondrion
0.42	GO:0031967	organelle envelope
0.41	GO:0031090	organelle membrane
0.38	GO:0031974	membrane-enclosed lumen
0.35	GO:0045277	respiratory chain complex IV
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.35

EC:1.9

GO:0016675

sp|P56392|CX7A1_MOUSE
Cytochrome c oxidase subunit 7A1, mitochondrial
Search

0.96	Cytochrome c oxidase subunit VIIa polypeptide 1

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.34	GO:0006879	cellular iron ion homeostasis
0.34	GO:0006826	iron ion transport
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity
0.34	GO:0008199	ferric iron binding
0.33	GO:0003676	nucleic acid binding

0.79	GO:0005746	mitochondrial respiratory chain
0.35	GO:0045277	respiratory chain complex IV
0.30	GO:0016021	integral component of membrane

0.65

GO:0016676

sp|P56393|COX7B_MOUSE
Cytochrome c oxidase subunit 7B, mitochondrial
Search

0.97	Cytochrome c oxidase polypeptide VIIb

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.47	GO:0007417	central nervous system development
0.36	GO:0060003	copper ion export
0.34	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.34	GO:0006119	oxidative phosphorylation
0.34	GO:0009060	aerobic respiration

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity
0.36	GO:0004008	copper-exporting ATPase activity
0.35	GO:0005507	copper ion binding
0.33	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.79	GO:0005746	mitochondrial respiratory chain
0.46	GO:0045277	respiratory chain complex IV
0.30	GO:0016021	integral component of membrane

0.65

GO:0016676

sp|P56394|COX17_MOUSE
Cytochrome c oxidase copper chaperone
Search

COX17

0.94	Mitochondrial cytochrome c oxidase copper chaperone

0.78	GO:0006825	copper ion transport
0.54	GO:1904734	positive regulation of electron transfer activity
0.54	GO:1904959	regulation of cytochrome-c oxidase activity
0.53	GO:0033617	mitochondrial respiratory chain complex IV assembly
0.50	GO:0032414	positive regulation of ion transmembrane transporter activity
0.50	GO:1904064	positive regulation of cation transmembrane transport
0.48	GO:0008284	positive regulation of cell proliferation
0.43	GO:0046688	response to copper ion
0.39	GO:0007507	heart development
0.39	GO:0007420	brain development

0.85	GO:0016531	copper chaperone activity
0.53	GO:1903136	cuprous ion binding
0.37	GO:0008047	enzyme activator activity
0.33	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0016874	ligase activity

0.79	GO:0005758	mitochondrial intermembrane space
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016874

sp|P56395|CYB5_MOUSE
Cytochrome b5
Search

CYB5A

0.63	Microsomal cytochrome b5 type A

0.42	GO:0071466	cellular response to xenobiotic stimulus
0.39	GO:0046686	response to cadmium ion
0.36	GO:0055114	oxidation-reduction process
0.35	GO:0019852	L-ascorbic acid metabolic process
0.34	GO:0006091	generation of precursor metabolites and energy
0.34	GO:0006631	fatty acid metabolic process
0.33	GO:1902600	hydrogen ion transmembrane transport

0.60	GO:0020037	heme binding
0.52	GO:0046872	metal ion binding
0.48	GO:0019899	enzyme binding
0.35	GO:0004768	stearoyl-CoA 9-desaturase activity
0.35	GO:0004033	aldo-keto reductase (NADP) activity
0.34	GO:0009055	electron transfer activity
0.33	GO:0015002	heme-copper terminal oxidase activity
0.33	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.47	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.41	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0031090	organelle membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0098805	whole membrane
0.33	GO:0019867	outer membrane
0.33	GO:0031967	organelle envelope
0.30	GO:0016021	integral component of membrane

0.35

EC:1.14.19.1

GO:0004768

sp|P56399|UBP5_MOUSE
Ubiquitin carboxyl-terminal hydrolase 5
Search

USP5

0.57	Ubiquitinyl hydrolase 1

0.76	GO:0016579	protein deubiquitination
0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.57	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.44	GO:1904888	cranial skeletal system development
0.44	GO:0009953	dorsal/ventral pattern formation
0.42	GO:1904378	maintenance of unfolded protein involved in ERAD pathway
0.42	GO:1904294	positive regulation of ERAD pathway
0.40	GO:0050821	protein stabilization
0.40	GO:0008283	cell proliferation
0.39	GO:0010506	regulation of autophagy

0.78	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.62	GO:0008270	zinc ion binding
0.57	GO:0043130	ubiquitin binding
0.43	GO:1904454	ubiquitin-specific protease activity involved in positive regulation of ERAD pathway
0.42	GO:1904288	BAT3 complex binding
0.40	GO:0070628	proteasome binding
0.39	GO:0031625	ubiquitin protein ligase binding
0.39	GO:0051087	chaperone binding
0.39	GO:0004197	cysteine-type endopeptidase activity

0.30

GO:0016020

membrane

0.39

EC:3.4.22

GO:0004197

sp|P56400|GP1BB_MOUSE
Platelet glycoprotein Ib beta chain
Search

GP1BB

0.96	Truncated platelet membrane glycoprotein Ib beta

0.47	GO:0007596	blood coagulation
0.46	GO:0045087	innate immune response
0.44	GO:0007155	cell adhesion
0.42	GO:0007165	signal transduction
0.40	GO:0046426	negative regulation of JAK-STAT cascade
0.39	GO:0006469	negative regulation of protein kinase activity
0.39	GO:0072376	protein activation cascade
0.38	GO:0071345	cellular response to cytokine stimulus
0.38	GO:0001775	cell activation
0.37	GO:0007601	visual perception

0.55	GO:0042802	identical protein binding
0.39	GO:0004860	protein kinase inhibitor activity
0.37	GO:0004888	transmembrane signaling receptor activity
0.35	GO:0005518	collagen binding
0.34	GO:0035374	chondroitin sulfate binding
0.34	GO:0004180	carboxypeptidase activity
0.34	GO:0001968	fibronectin binding
0.34	GO:0043236	laminin binding
0.34	GO:0098633	collagen fibril binding
0.34	GO:0008201	heparin binding

0.39	GO:0031226	intrinsic component of plasma membrane
0.37	GO:0031012	extracellular matrix
0.35	GO:0005615	extracellular space
0.34	GO:0008021	synaptic vesicle
0.34	GO:0031225	anchored component of membrane
0.33	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

0.33

GO:0016705

sp|P56402|AQP2_MOUSE
Aquaporin-2
Search

AQP2

0.95	Aquaporin-2

0.60	GO:0071288	cellular response to mercury ion
0.59	GO:0071280	cellular response to copper ion
0.58	GO:0015793	glycerol transport
0.58	GO:0072205	metanephric collecting duct development
0.58	GO:0003097	renal water transport
0.57	GO:0042631	cellular response to water deprivation
0.55	GO:0055085	transmembrane transport
0.38	GO:0006811	ion transport
0.36	GO:0033762	response to glucagon
0.36	GO:0010226	response to lithium ion

0.69	GO:0022803	passive transmembrane transporter activity
0.59	GO:0015168	glycerol transmembrane transporter activity
0.57	GO:0005372	water transmembrane transporter activity
0.35	GO:0030165	PDZ domain binding
0.34	GO:0003779	actin binding
0.34	GO:0042802	identical protein binding

0.57	GO:0016324	apical plasma membrane
0.54	GO:0055037	recycling endosome
0.54	GO:0070062	extracellular exosome
0.44	GO:0016323	basolateral plasma membrane
0.42	GO:0030659	cytoplasmic vesicle membrane
0.41	GO:0005794	Golgi apparatus
0.40	GO:0005887	integral component of plasma membrane
0.36	GO:0046930	pore complex
0.36	GO:0030133	transport vesicle
0.36	GO:0031303	integral component of endosome membrane

sp|P56404|AQP8_MOUSE
Aquaporin-8
Search

AQP8

0.88	Aquaporin 8a, tandem duplicate 1

0.64	GO:0006833	water transport
0.56	GO:0071320	cellular response to cAMP
0.55	GO:0055085	transmembrane transport
0.42	GO:0015840	urea transport
0.39	GO:0006811	ion transport
0.35	GO:0046717	acid secretion
0.35	GO:0015850	organic hydroxy compound transport
0.34	GO:0006869	lipid transport
0.34	GO:0032259	methylation
0.34	GO:0015849	organic acid transport

0.69	GO:0022803	passive transmembrane transporter activity
0.59	GO:0005372	water transmembrane transporter activity
0.42	GO:0015204	urea transmembrane transporter activity
0.34	GO:0008168	methyltransferase activity

0.53	GO:0045177	apical part of cell
0.43	GO:0005886	plasma membrane
0.36	GO:0042807	central vacuole
0.36	GO:0009705	plant-type vacuole membrane
0.35	GO:0046930	pore complex
0.33	GO:0031410	cytoplasmic vesicle

0.34

GO:0008168

sp|P56450|MC4R_MOUSE
Melanocortin receptor 4
Search

MC4R

0.94	Mutated melanocortin receptor 4

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.57	GO:0045780	positive regulation of bone resorption
0.55	GO:0019933	cAMP-mediated signaling
0.48	GO:0030073	insulin secretion
0.47	GO:0007631	feeding behavior
0.46	GO:0032868	response to insulin
0.39	GO:2000821	regulation of grooming behavior
0.38	GO:2000252	negative regulation of feeding behavior
0.38	GO:0002024	diet induced thermogenesis
0.38	GO:0019222	regulation of metabolic process

0.84	GO:0004977	melanocortin receptor activity
0.57	GO:0042923	neuropeptide binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.38	GO:0017046	peptide hormone binding

0.55	GO:0005886	plasma membrane
0.37	GO:0005622	intracellular
0.34	GO:0043227	membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

sp|P56469|CORT_MOUSE
Cortistatin
Search

CORT

0.97	CENPS-CORT readthrough

0.76	GO:0010469	regulation of receptor activity
0.56	GO:0000712	resolution of meiotic recombination intermediates
0.56	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.55	GO:0031297	replication fork processing
0.54	GO:0006312	mitotic recombination
0.54	GO:0036297	interstrand cross-link repair
0.53	GO:0051382	kinetochore assembly
0.41	GO:0045187	regulation of circadian sleep/wake cycle, sleep
0.39	GO:0007218	neuropeptide signaling pathway
0.38	GO:0007267	cell-cell signaling

0.79	GO:0005179	hormone activity
0.53	GO:0001664	G-protein coupled receptor binding
0.52	GO:0003682	chromatin binding
0.50	GO:0046982	protein heterodimerization activity
0.49	GO:0003690	double-stranded DNA binding
0.34	GO:0008408	3'-5' exonuclease activity
0.34	GO:0044877	macromolecular complex binding
0.34	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.66	GO:0005576	extracellular region
0.64	GO:0071821	FANCM-MHF complex
0.56	GO:0043240	Fanconi anaemia nuclear complex
0.51	GO:0000776	kinetochore
0.35	GO:0000176	nuclear exosome (RNase complex)

0.34

GO:0004674

sp|P56473|AGRP_MOUSE
Agouti-related protein
Search

AGRP

0.93	Agouti related neuropeptide

0.77	GO:0009755	hormone-mediated signaling pathway
0.65	GO:0060259	regulation of feeding behavior
0.63	GO:0008343	adult feeding behavior
0.61	GO:0007218	neuropeptide signaling pathway
0.58	GO:0010469	regulation of receptor activity
0.48	GO:0048520	positive regulation of behavior
0.45	GO:0048571	long-day photoperiodism
0.45	GO:0042755	eating behavior
0.45	GO:0060135	maternal process involved in female pregnancy
0.44	GO:0032868	response to insulin

0.72	GO:0005102	receptor binding
0.58	GO:0030545	receptor regulator activity

0.66	GO:0005576	extracellular region
0.64	GO:0005796	Golgi lumen
0.43	GO:0043025	neuronal cell body
0.37	GO:0031982	vesicle

sp|P56475|GBRR1_MOUSE
Gamma-aminobutyric acid receptor subunit rho-1
Search

GABRR1

0.96	LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit rho-1

0.59	GO:0007165	signal transduction
0.59	GO:0034220	ion transmembrane transport
0.46	GO:0007601	visual perception
0.38	GO:0006821	chloride transport
0.34	GO:0007268	chemical synaptic transmission

0.75	GO:0004890	GABA-A receptor activity
0.74	GO:0005230	extracellular ligand-gated ion channel activity
0.38	GO:0005254	chloride channel activity
0.34	GO:0019904	protein domain specific binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0046982	protein heterodimerization activity

0.54	GO:0005886	plasma membrane
0.52	GO:1902711	GABA-A receptor complex
0.39	GO:0034707	chloride channel complex
0.38	GO:0098794	postsynapse
0.38	GO:0030054	cell junction

sp|P56476|GBRR2_MOUSE
Gamma-aminobutyric acid receptor subunit rho-2
Search

GABRR2

0.97	Gamma-aminobutyric acid receptor subunit rho-2

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.51	GO:0007601	visual perception
0.38	GO:0006821	chloride transport
0.37	GO:0042462	eye photoreceptor cell development
0.35	GO:0007268	chemical synaptic transmission

0.79	GO:0004890	GABA-A receptor activity
0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.39	GO:0005254	chloride channel activity
0.37	GO:0019904	protein domain specific binding
0.32	GO:0003676	nucleic acid binding

0.56	GO:0005886	plasma membrane
0.52	GO:1902711	GABA-A receptor complex
0.39	GO:0034707	chloride channel complex
0.39	GO:0098794	postsynapse
0.38	GO:0030054	cell junction
0.34	GO:0030424	axon

sp|P56477|IRF5_MOUSE
Interferon regulatory factor 5
Search

IRF5

0.94	Interferon regulatory factor 5

0.75	GO:0019221	cytokine-mediated signaling pathway
0.73	GO:0051607	defense response to virus
0.68	GO:0006357	regulation of transcription by RNA polymerase II
0.62	GO:0032494	response to peptidoglycan
0.62	GO:0032495	response to muramyl dipeptide
0.56	GO:0006351	transcription, DNA-templated
0.56	GO:0043065	positive regulation of apoptotic process
0.55	GO:0045893	positive regulation of transcription, DNA-templated
0.45	GO:0043616	keratinocyte proliferation
0.45	GO:0060644	mammary gland epithelial cell differentiation

0.74	GO:0044212	transcription regulatory region DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.53	GO:0042802	identical protein binding
0.50	GO:0043565	sequence-specific DNA binding
0.34	GO:0004952	dopamine neurotransmitter receptor activity
0.33	GO:0005509	calcium ion binding

0.59	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm
0.41	GO:0030054	cell junction
0.34	GO:0070062	extracellular exosome
0.33	GO:0005887	integral component of plasma membrane

sp|P56479|GALR1_MOUSE
Galanin receptor type 1
Search

GALR1

0.97	Galanin receptor

0.81	GO:0007194	negative regulation of adenylate cyclase activity
0.75	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.74	GO:0007218	neuropeptide signaling pathway
0.58	GO:0051464	positive regulation of cortisol secretion
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.47	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.39	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.35	GO:0007586	digestion

0.83	GO:0004966	galanin receptor activity
0.56	GO:0017046	peptide hormone binding
0.39	GO:0042923	neuropeptide binding
0.33	GO:0005515	protein binding

0.42	GO:0005887	integral component of plasma membrane
0.33	GO:0005622	intracellular

sp|P56480|ATPB_MOUSE
ATP synthase subunit beta, mitochondrial
Search

ATP5B

0.43	Mitochondrial ATP synthase subunit beta

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.54	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration
0.53	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.51	GO:0051453	regulation of intracellular pH
0.51	GO:0001525	angiogenesis
0.42	GO:0006629	lipid metabolic process
0.37	GO:0001649	osteoblast differentiation
0.35	GO:0042407	cristae formation

0.71	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.55	GO:0043532	angiostatin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0042288	MHC class I protein binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.35	GO:0030228	lipoprotein particle receptor activity
0.34	GO:0005509	calcium ion binding
0.32	GO:0003677	DNA binding

0.72	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.51	GO:0042645	mitochondrial nucleoid
0.50	GO:0043209	myelin sheath
0.49	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.48	GO:0009986	cell surface
0.40	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:0005634	nucleus
0.34	GO:0045121	membrane raft

sp|P56481|GASR_MOUSE
Gastrin/cholecystokinin type B receptor
Search

CCKBR

0.89	Cholecystokinin receptor type A

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.55	GO:0001696	gastric acid secretion
0.55	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.54	GO:0008284	positive regulation of cell proliferation
0.53	GO:0048565	digestive tract development
0.51	GO:0048732	gland development
0.39	GO:0001764	neuron migration
0.39	GO:0007610	behavior
0.39	GO:0030900	forebrain development
0.38	GO:0007409	axonogenesis

0.85	GO:0015054	gastrin receptor activity
0.60	GO:0031741	type B gastrin/cholecystokinin receptor binding
0.57	GO:0004951	cholecystokinin receptor activity
0.36	GO:0042277	peptide binding
0.36	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity
0.35	GO:0004435	phosphatidylinositol phospholipase C activity
0.32	GO:0005216	ion channel activity

0.37	GO:0005886	plasma membrane
0.33	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.35	EC:3.1.4.11	GO:0004435
0.35	KEGG:R03435	GO:0004435

sp|P56484|CCR8_MOUSE
C-C chemokine receptor type 8
Search

CCR8

0.95	C-C motif chemokine receptor 8

0.84	GO:0070098	chemokine-mediated signaling pathway
0.71	GO:0006935	chemotaxis
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.62	GO:0006955	immune response
0.62	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.59	GO:0006954	inflammatory response
0.49	GO:0090026	positive regulation of monocyte chemotaxis
0.44	GO:0051094	positive regulation of developmental process
0.44	GO:0051240	positive regulation of multicellular organismal process
0.44	GO:2000026	regulation of multicellular organismal development

0.84	GO:0004950	chemokine receptor activity
0.50	GO:0019956	chemokine binding
0.41	GO:0004435	phosphatidylinositol phospholipase C activity
0.36	GO:0015026	coreceptor activity
0.34	GO:0004535	poly(A)-specific ribonuclease activity
0.34	GO:0005044	scavenger receptor activity
0.33	GO:0003779	actin binding
0.32	GO:0008289	lipid binding

0.45	GO:0009897	external side of plasma membrane
0.36	GO:0043025	neuronal cell body
0.34	GO:0005887	integral component of plasma membrane
0.34	GO:0042629	mast cell granule
0.33	GO:0005768	endosome
0.33	GO:0005654	nucleoplasm
0.32	GO:0005576	extracellular region

0.41	EC:3.1.4.11	GO:0004435
0.41	KEGG:R03435	GO:0004435

sp|P56485|ACKR3_MOUSE
Atypical chemokine receptor 3
Search

ACKR3

0.97	C-X-C chemokine receptor type 7

0.85	GO:0001570	vasculogenesis
0.81	GO:0001525	angiogenesis
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.71	GO:0006935	chemotaxis
0.61	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.60	GO:0031623	receptor internalization
0.59	GO:0070098	chemokine-mediated signaling pathway
0.59	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.46	GO:0048920	posterior lateral line neuromast primordium migration
0.42	GO:1905322	positive regulation of mesenchymal stem cell migration

0.85	GO:0019956	chemokine binding
0.85	GO:0015026	coreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.58	GO:0004896	cytokine receptor activity
0.57	GO:0005044	scavenger receptor activity
0.56	GO:0001653	peptide receptor activity
0.34	GO:0035091	phosphatidylinositol binding
0.33	GO:0042923	neuropeptide binding
0.33	GO:0016500	protein-hormone receptor activity
0.32	GO:0030594	neurotransmitter receptor activity

0.57	GO:0005905	clathrin-coated pit
0.54	GO:0009986	cell surface
0.54	GO:0005768	endosome
0.44	GO:0005886	plasma membrane
0.44	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0061827	sperm head
0.33	GO:0097225	sperm midpiece
0.32	GO:0043005	neuron projection
0.30	GO:0016021	integral component of membrane

sp|P56501|UCP3_MOUSE
Mitochondrial uncoupling protein 3
Search

UCP3

0.89	Mitochondrial uncoupling protein A

0.76	GO:0006839	mitochondrial transport
0.53	GO:0001666	response to hypoxia
0.52	GO:0051881	regulation of mitochondrial membrane potential
0.52	GO:1990845	adaptive thermogenesis
0.50	GO:0000303	response to superoxide
0.49	GO:0009409	response to cold
0.46	GO:0015992	proton transport
0.46	GO:0006631	fatty acid metabolic process
0.44	GO:0032868	response to insulin
0.43	GO:0007568	aging

0.61	GO:0017077	oxidative phosphorylation uncoupler activity
0.34	GO:0005515	protein binding
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.61	GO:0031966	mitochondrial membrane
0.42	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P56528|CD38_MOUSE
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
Search

CD38

0.97	ADP-ribosyl cyclase 1

0.48	GO:0030890	positive regulation of B cell proliferation
0.48	GO:0050853	B cell receptor signaling pathway
0.45	GO:0043066	negative regulation of apoptotic process
0.44	GO:0045893	positive regulation of transcription, DNA-templated
0.43	GO:0045892	negative regulation of transcription, DNA-templated
0.43	GO:0042493	response to drug

0.87	GO:0050135	NAD(P)+ nucleosidase activity
0.86	GO:0003953	NAD+ nucleosidase activity
0.44	GO:0016849	phosphorus-oxygen lyase activity
0.44	GO:0042802	identical protein binding

0.45	GO:0009986	cell surface
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.87

EC:3.2.2.6

GO:0050135

sp|P56542|DNS2A_MOUSE
Deoxyribonuclease-2-alpha
Search

DNASE2

0.61	Deoxyribonuclease II alpha

0.61	GO:0000737	DNA catabolic process, endonucleolytic
0.58	GO:0030218	erythrocyte differentiation
0.52	GO:0030262	apoptotic nuclear changes
0.33	GO:0009405	pathogenesis

0.84	GO:0004531	deoxyribonuclease II activity
0.34	GO:0090729	toxin activity
0.33	GO:0003677	DNA binding

0.41	GO:0005764	lysosome
0.37	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.84

EC:3.1.22.1

GO:0004531

sp|P56546|CTBP2_MOUSE
C-terminal-binding protein 2
Search

CTBP2

0.92	C-terminal-binding protein 2

0.52	GO:0048386	positive regulation of retinoic acid receptor signaling pathway
0.52	GO:0050872	white fat cell differentiation
0.52	GO:0055114	oxidation-reduction process
0.51	GO:0035563	positive regulation of chromatin binding
0.49	GO:1990823	response to leukemia inhibitory factor
0.47	GO:0071345	cellular response to cytokine stimulus
0.46	GO:0045944	positive regulation of transcription by RNA polymerase II
0.46	GO:1903507	negative regulation of nucleic acid-templated transcription
0.45	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.44	GO:0010629	negative regulation of gene expression

0.67	GO:0051287	NAD binding
0.65	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.51	GO:0042974	retinoic acid receptor binding
0.49	GO:0003714	transcription corepressor activity
0.47	GO:0003713	transcription coactivator activity
0.47	GO:0003682	chromatin binding
0.46	GO:0019901	protein kinase binding
0.45	GO:0032403	protein complex binding
0.42	GO:0042803	protein homodimerization activity

0.52	GO:0097470	ribbon synapse
0.49	GO:0017053	transcriptional repressor complex
0.42	GO:0005634	nucleus
0.40	GO:0005829	cytosol
0.39	GO:0030054	cell junction

0.65

EC:1.1.1

GO:0016616

sp|P56563|LMIP_MOUSE
Lens fiber membrane intrinsic protein
Search

0.97	Lens intrinsic membrane protein 2

0.52	GO:0002088	lens development in camera-type eye
0.36	GO:0007043	cell-cell junction assembly

0.84

GO:0005212

structural constituent of eye lens

0.38	GO:0031982	vesicle
0.37	GO:0030054	cell junction
0.35	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P56564|EAA1_MOUSE
Excitatory amino acid transporter 1
Search

SLC1A3

0.45	Amino acid transporter

0.59	GO:0140016	D-aspartate import across plasma membrane
0.59	GO:0140009	L-aspartate import across plasma membrane
0.59	GO:0009449	gamma-aminobutyric acid biosynthetic process
0.58	GO:0098712	L-glutamate import across plasma membrane
0.57	GO:0031223	auditory behavior
0.56	GO:0021545	cranial nerve development
0.55	GO:0050885	neuromuscular process controlling balance
0.55	GO:0050806	positive regulation of synaptic transmission
0.53	GO:0007605	sensory perception of sound
0.52	GO:0048667	cell morphogenesis involved in neuron differentiation

0.72	GO:0015293	symporter activity
0.58	GO:0016595	glutamate binding
0.55	GO:0005313	L-glutamate transmembrane transporter activity
0.50	GO:0015081	sodium ion transmembrane transporter activity
0.48	GO:0022853	active ion transmembrane transporter activity
0.35	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.53	GO:0043025	neuronal cell body
0.51	GO:0043005	neuron projection
0.51	GO:0009986	cell surface
0.47	GO:0005887	integral component of plasma membrane
0.35	GO:0045111	intermediate filament cytoskeleton
0.35	GO:0016323	basolateral plasma membrane
0.34	GO:0098794	postsynapse
0.34	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0005794	Golgi apparatus
0.33	GO:0019866	organelle inner membrane

sp|P56565|S10A1_MOUSE
Protein S100-A1
Search

sp|P56567|CYTA_MOUSE
Cystatin-A
Search

CSTA

0.85	Cystatin-A

0.76	GO:0010951	negative regulation of endopeptidase activity
0.58	GO:0030216	keratinocyte differentiation
0.58	GO:0018149	peptide cross-linking
0.54	GO:0098609	cell-cell adhesion
0.36	GO:0012501	programmed cell death

0.82	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.60	GO:0002020	protease binding
0.57	GO:0030674	protein binding, bridging
0.47	GO:0005198	structural molecule activity

0.61	GO:0001533	cornified envelope
0.54	GO:0005615	extracellular space
0.51	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.40	GO:0031012	extracellular matrix
0.36	GO:1903561	extracellular vesicle

sp|P56581|TDG_MOUSE
G/T mismatch-specific thymine DNA glycosylase
Search

TDG

0.93	LOW QUALITY PROTEIN: G/T mismatch-specific thymine DNA glycosylase

0.63	GO:0006281	DNA repair
0.62	GO:1902544	regulation of DNA N-glycosylase activity
0.60	GO:0035562	negative regulation of chromatin binding
0.57	GO:0032091	negative regulation of protein binding
0.57	GO:0080111	DNA demethylation
0.54	GO:0040029	regulation of gene expression, epigenetic
0.54	GO:0000122	negative regulation of transcription by RNA polymerase II
0.52	GO:0009790	embryo development
0.38	GO:0009223	pyrimidine deoxyribonucleotide catabolic process
0.36	GO:0016569	covalent chromatin modification

0.72	GO:0019104	DNA N-glycosylase activity
0.60	GO:0031404	chloride ion binding
0.60	GO:0032183	SUMO binding
0.59	GO:0005080	protein kinase C binding
0.58	GO:0043621	protein self-association
0.56	GO:0031402	sodium ion binding
0.54	GO:0001104	RNA polymerase II transcription cofactor activity
0.53	GO:0030983	mismatched DNA binding
0.53	GO:0042803	protein homodimerization activity
0.47	GO:0000287	magnesium ion binding

0.57	GO:0016605	PML body
0.43	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.72

EC:3.2.2

GO:0019104

sp|P56593|CP2AC_MOUSE
Cytochrome P450 2A12
Search

0.71	Coumarin 7-hydroxylase

0.58	GO:0019373	epoxygenase P450 pathway
0.53	GO:0055114	oxidation-reduction process
0.40	GO:0009804	coumarin metabolic process
0.39	GO:0042738	exogenous drug catabolic process
0.39	GO:0035634	response to stilbenoid
0.38	GO:0006805	xenobiotic metabolic process
0.37	GO:0008202	steroid metabolic process
0.37	GO:0071276	cellular response to cadmium ion
0.35	GO:0042180	cellular ketone metabolic process
0.35	GO:0042168	heme metabolic process

0.78	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.58	GO:0008392	arachidonic acid epoxygenase activity
0.56	GO:0008395	steroid hydroxylase activity
0.41	GO:0008389	coumarin 7-hydroxylase activity
0.38	GO:0019825	oxygen binding
0.36	GO:0019899	enzyme binding

0.43	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0031090	organelle membrane
0.38	GO:0005881	cytoplasmic microtubule
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:1.14.14

GO:0016712

sp|P56654|CP237_MOUSE
Cytochrome P450 2C37
Search

0.93	Cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1

0.69	GO:0019369	arachidonic acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.48	GO:0043651	linoleic acid metabolic process

0.72	GO:0008392	arachidonic acid epoxygenase activity
0.65	GO:0008395	steroid hydroxylase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.49	GO:0071614	linoleic acid epoxygenase activity
0.49	GO:0034875	caffeine oxidase activity
0.44	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.37	GO:0008144	drug binding

0.37

GO:0043231

intracellular membrane-bounded organelle

0.49

EC:1.17.5

GO:0034875

sp|P56655|CP238_MOUSE
Cytochrome P450 2C38
Search

0.97	Cytochrome P450 family 2 subfamily C polypeptide 9

0.59	GO:0019369	arachidonic acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.48	GO:0042738	exogenous drug catabolic process
0.45	GO:0043651	linoleic acid metabolic process
0.44	GO:0016098	monoterpenoid metabolic process
0.44	GO:0008202	steroid metabolic process
0.43	GO:0070988	demethylation
0.43	GO:0002933	lipid hydroxylation
0.38	GO:0006805	xenobiotic metabolic process
0.38	GO:0019627	urea metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.49	GO:0034875	caffeine oxidase activity
0.38	GO:0019825	oxygen binding
0.36	GO:0019899	enzyme binding

0.46	GO:0005789	endoplasmic reticulum membrane
0.42	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|P56656|CP239_MOUSE
Cytochrome P450 2C39
Search

0.96	Cytochrome P450 family 2 subfamily C polypeptide 9

0.56	GO:0042738	exogenous drug catabolic process
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0019373	epoxygenase P450 pathway
0.50	GO:0002933	lipid hydroxylation
0.49	GO:0008202	steroid metabolic process
0.48	GO:0070988	demethylation
0.48	GO:0016098	monoterpenoid metabolic process
0.42	GO:0097267	omega-hydroxylase P450 pathway
0.39	GO:0006805	xenobiotic metabolic process
0.39	GO:0019627	urea metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.55	GO:0034875	caffeine oxidase activity
0.39	GO:0019899	enzyme binding
0.39	GO:0019825	oxygen binding

0.43	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|P56657|CP240_MOUSE
Cytochrome P450 2C40
Search

0.97	Cytochrome P450 family 2 subfamily C polypeptide 9

0.60	GO:0019369	arachidonic acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.48	GO:0042738	exogenous drug catabolic process
0.44	GO:0043651	linoleic acid metabolic process
0.44	GO:0016098	monoterpenoid metabolic process
0.43	GO:0008202	steroid metabolic process
0.43	GO:0070988	demethylation
0.42	GO:0002933	lipid hydroxylation
0.38	GO:0006805	xenobiotic metabolic process
0.38	GO:0019627	urea metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.50	GO:0034875	caffeine oxidase activity
0.38	GO:0019825	oxygen binding
0.36	GO:0019899	enzyme binding

0.46	GO:0005789	endoplasmic reticulum membrane
0.42	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|P56671|MAZ_MOUSE
Myc-associated zinc finger protein
Search

MAZ

0.92	MYC-associated zinc finger protein a (purine-binding transcription factor)

0.53	GO:0006369	termination of RNA polymerase II transcription
0.50	GO:0006367	transcription initiation from RNA polymerase II promoter
0.43	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0001885	endothelial cell development
0.39	GO:0048731	system development
0.38	GO:0060322	head development
0.37	GO:0048646	anatomical structure formation involved in morphogenesis
0.36	GO:0009607	response to biotic stimulus
0.36	GO:0007018	microtubule-based movement
0.34	GO:0006968	cellular defense response

0.54	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.42	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.41	GO:0003682	chromatin binding
0.37	GO:0005515	protein binding
0.37	GO:0003723	RNA binding
0.36	GO:0003777	microtubule motor activity
0.35	GO:0046872	metal ion binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding

0.40	GO:0005634	nucleus
0.36	GO:0043233	organelle lumen
0.36	GO:0044446	intracellular organelle part
0.35	GO:0099512	supramolecular fiber
0.35	GO:0015630	microtubule cytoskeleton
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.7.8

GO:0016780

sp|P56677|ST14_MOUSE
Suppressor of tumorigenicity 14 protein homolog
Search

ST14

0.76	Suppressor of tumorigenicity 14 protein homolog

0.60	GO:0006508	proteolysis
0.59	GO:0060672	epithelial cell morphogenesis involved in placental branching
0.58	GO:0030216	keratinocyte differentiation
0.57	GO:0001843	neural tube closure
0.35	GO:0016477	cell migration
0.35	GO:0012501	programmed cell death
0.34	GO:0010951	negative regulation of endopeptidase activity
0.32	GO:0022617	extracellular matrix disassembly
0.32	GO:0006952	defense response

0.69	GO:0004252	serine-type endopeptidase activity
0.35	GO:0008201	heparin binding
0.35	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0046914	transition metal ion binding
0.32	GO:0005515	protein binding

0.53	GO:0019897	extrinsic component of plasma membrane
0.48	GO:0005576	extracellular region
0.40	GO:0016323	basolateral plasma membrane
0.36	GO:0031982	vesicle
0.35	GO:0005887	integral component of plasma membrane

0.69