Queries 4001 to 5000

GO:0016874

sp|O08760|OGG1_MOUSE
N-glycosylase/DNA lyase
Search

OGG1

0.53	8-oxoguanine DNA glycosylase

0.72	GO:0006284	base-excision repair
0.72	GO:0006289	nucleotide-excision repair
0.62	GO:1901291	negative regulation of double-strand break repair via single-strand annealing
0.59	GO:0033158	regulation of protein import into nucleus, translocation
0.53	GO:0009314	response to radiation
0.50	GO:0006979	response to oxidative stress
0.47	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.44	GO:0051593	response to folic acid
0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.79	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity
0.72	GO:0003684	damaged DNA binding
0.53	GO:0008017	microtubule binding
0.49	GO:0016829	lyase activity
0.34	GO:0004519	endonuclease activity
0.33	GO:0005381	iron ion transmembrane transporter activity
0.33	GO:0046872	metal ion binding

0.57	GO:0016363	nuclear matrix
0.55	GO:0016607	nuclear speck
0.46	GO:0005739	mitochondrion
0.45	GO:0043234	protein complex
0.32	GO:0000775	chromosome, centromeric region
0.30	GO:0016020	membrane

0.79

EC:3.2.2.23

GO:0008534

sp|O08762|NETR_MOUSE
Neurotrypsin
Search

0.55	Neurotrypsin

0.65	GO:0006898	receptor-mediated endocytosis
0.59	GO:0006508	proteolysis
0.30	GO:0032940	secretion by cell
0.30	GO:0051604	protein maturation

0.73	GO:0005044	scavenger receptor activity
0.67	GO:0004252	serine-type endopeptidase activity

0.30	GO:0043005	neuron projection
0.30	GO:0045202	synapse
0.30	GO:0071944	cell periphery
0.30	GO:0005737	cytoplasm
0.30	GO:0031982	vesicle
0.30	GO:0043229	intracellular organelle
0.30	GO:0120038	plasma membrane bounded cell projection part
0.30	GO:0005576	extracellular region
0.30	GO:0036477	somatodendritic compartment
0.30	GO:0031224	intrinsic component of membrane

0.67

GO:0004252

sp|O08784|TCOF_MOUSE
Treacle protein
Search

TCOF1

0.86	treacle protein isoform X1

0.82	GO:0014029	neural crest formation
0.79	GO:0014032	neural crest cell development
0.67	GO:0006417	regulation of translation
0.44	GO:0048701	embryonic cranial skeleton morphogenesis
0.43	GO:0042790	nucleolar large rRNA transcription by RNA polymerase I
0.34	GO:0005975	carbohydrate metabolic process
0.33	GO:0055114	oxidation-reduction process

0.84	GO:0001042	RNA polymerase I core binding
0.80	GO:0097110	scaffold protein binding
0.69	GO:0046982	protein heterodimerization activity
0.38	GO:0003723	RNA binding
0.36	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.36	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.35	GO:0046872	metal ion binding
0.35	GO:0020037	heme binding

0.78	GO:0001650	fibrillar center
0.64	GO:0005829	cytosol
0.38	GO:0070701	mucus layer

0.36

GO:0003899

sp|O08785|CLOCK_MOUSE
Circadian locomoter output cycles protein kaput
Search

CLOCK

0.89	Circadian rhythmicity protein CLOCK

0.65	GO:0032922	circadian regulation of gene expression
0.64	GO:2000074	regulation of type B pancreatic cell development
0.64	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway
0.62	GO:0042634	regulation of hair cycle
0.61	GO:0071479	cellular response to ionizing radiation
0.60	GO:0050729	positive regulation of inflammatory response
0.60	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.60	GO:0050796	regulation of insulin secretion
0.59	GO:0051775	response to redox state
0.58	GO:0000077	DNA damage checkpoint

0.68	GO:0046983	protein dimerization activity
0.62	GO:0070888	E-box binding
0.61	GO:0003700	DNA binding transcription factor activity
0.61	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.60	GO:0001046	core promoter sequence-specific DNA binding
0.60	GO:0031490	chromatin DNA binding
0.57	GO:0004402	histone acetyltransferase activity

0.75	GO:0005667	transcription factor complex
0.63	GO:0033391	chromatoid body
0.61	GO:0005634	nucleus
0.51	GO:0005829	cytosol
0.51	GO:0005694	chromosome
0.51	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part

0.57

EC:2.3.1.48

GO:0004402

sp|O08786|CCKAR_MOUSE
Cholecystokinin receptor type A
Search

CCKAR

0.96	Cholecystokinin receptor type A

0.79	GO:0038188	cholecystokinin signaling pathway
0.57	GO:0001764	neuron migration
0.55	GO:0030900	forebrain development
0.54	GO:0007409	axonogenesis
0.47	GO:0007631	feeding behavior
0.47	GO:0007586	digestion
0.47	GO:0046883	regulation of hormone secretion
0.46	GO:1901652	response to peptide
0.45	GO:0032870	cellular response to hormone stimulus
0.37	GO:0007584	response to nutrient

0.79	GO:0004951	cholecystokinin receptor activity
0.70	GO:0015054	gastrin receptor activity
0.46	GO:0042277	peptide binding

0.42	GO:0005887	integral component of plasma membrane
0.35	GO:0043195	terminal bouton
0.35	GO:0005764	lysosome
0.34	GO:0005768	endosome
0.34	GO:0005783	endoplasmic reticulum

sp|O08788|DCTN1_MOUSE
Dynactin subunit 1
Search

DCTN1

0.86	Dynactin subunit 1

0.81	GO:0010970	transport along microtubule
0.55	GO:0090063	positive regulation of microtubule nucleation
0.54	GO:0051081	nuclear envelope disassembly
0.53	GO:0010457	centriole-centriole cohesion
0.53	GO:0032402	melanosome transport
0.53	GO:0034454	microtubule anchoring at centrosome
0.53	GO:0000132	establishment of mitotic spindle orientation
0.52	GO:0060236	regulation of mitotic spindle organization
0.52	GO:1905515	non-motile cilium assembly
0.50	GO:0042147	retrograde transport, endosome to Golgi

0.84	GO:0070840	dynein complex binding
0.49	GO:0019901	protein kinase binding
0.48	GO:0008017	microtubule binding
0.38	GO:0003774	motor activity
0.34	GO:0042802	identical protein binding

0.81	GO:0005869	dynactin complex
0.54	GO:0120103	centriolar subdistal appendage
0.53	GO:0035371	microtubule plus-end
0.52	GO:0099738	cell cortex region
0.52	GO:0005814	centriole
0.51	GO:0030904	retromer complex
0.50	GO:0005813	centrosome
0.50	GO:0031252	cell leading edge
0.50	GO:0000776	kinetochore
0.50	GO:0000922	spindle pole

sp|O08789|MNT_MOUSE
Max-binding protein MNT
Search

MNT

0.97	MAX network transcriptional repressor b

0.64	GO:2001234	negative regulation of apoptotic signaling pathway
0.63	GO:0007569	cell aging
0.60	GO:0000122	negative regulation of transcription by RNA polymerase II
0.57	GO:0051726	regulation of cell cycle

0.68	GO:0046983	protein dimerization activity
0.63	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.60	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.60	GO:0003682	chromatin binding

0.55

GO:0005654

nucleoplasm

sp|O08790|FPRS1_MOUSE
Formyl peptide receptor-related sequence 1
Search

0.95	Formyl peptide receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.55	GO:0002430	complement receptor mediated signaling pathway
0.52	GO:0050900	leukocyte migration
0.51	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.51	GO:0060326	cell chemotaxis
0.51	GO:0006954	inflammatory response
0.50	GO:0071675	regulation of mononuclear cell migration
0.49	GO:0002690	positive regulation of leukocyte chemotaxis
0.49	GO:1904646	cellular response to amyloid-beta
0.47	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.84	GO:0004982	N-formyl peptide receptor activity
0.55	GO:0004875	complement receptor activity
0.51	GO:0005124	scavenger receptor binding
0.38	GO:0050786	RAGE receptor binding
0.36	GO:0038024	cargo receptor activity

0.45	GO:0005887	integral component of plasma membrane
0.37	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0035579	specific granule membrane
0.35	GO:0070821	tertiary granule membrane
0.35	GO:0035577	azurophil granule membrane
0.34	GO:0060417	yolk
0.32	GO:0005829	cytosol

sp|O08791|COE3_MOUSE
Transcription factor COE3
Search

0.88	Transcription factor COE3

0.70	GO:0007275	multicellular organism development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.40	GO:0051254	positive regulation of RNA metabolic process
0.39	GO:0010557	positive regulation of macromolecule biosynthetic process
0.39	GO:0031328	positive regulation of cellular biosynthetic process

0.68	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.54	GO:0046872	metal ion binding
0.38	GO:0001067	regulatory region nucleic acid binding

0.61

GO:0005634

nucleus

sp|O08792|COE2_MOUSE
Transcription factor COE2
Search

EBF2

0.96	Early B-cell factor 2

0.70	GO:0007275	multicellular organism development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0035563	positive regulation of chromatin binding
0.56	GO:0010468	regulation of gene expression
0.54	GO:0001709	cell fate determination
0.53	GO:0050873	brown fat cell differentiation
0.53	GO:0061448	connective tissue development
0.49	GO:0051254	positive regulation of RNA metabolic process

0.68	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.54	GO:0046872	metal ion binding
0.51	GO:0003682	chromatin binding
0.50	GO:0001067	regulatory region nucleic acid binding

0.61

GO:0005634

nucleus

sp|O08795|GLU2B_MOUSE
Glucosidase 2 subunit beta
Search

PRKCSH

0.85	LOW QUALITY PROTEIN: glucosidase 2 subunit beta

0.84	GO:0006491	N-glycan processing
0.61	GO:0001889	liver development
0.59	GO:0072001	renal system development
0.57	GO:0010977	negative regulation of neuron projection development
0.54	GO:0001701	in utero embryonic development
0.40	GO:0016310	phosphorylation
0.40	GO:0051291	protein heterooligomerization
0.35	GO:0043687	post-translational protein modification
0.34	GO:0006457	protein folding
0.34	GO:0035556	intracellular signal transduction

0.67	GO:0005509	calcium ion binding
0.44	GO:0003723	RNA binding
0.41	GO:0016301	kinase activity
0.40	GO:0005080	protein kinase C binding
0.40	GO:0044325	ion channel binding
0.40	GO:0051219	phosphoprotein binding
0.32	GO:0016787	hydrolase activity

0.51	GO:0005783	endoplasmic reticulum
0.34	GO:0044446	intracellular organelle part
0.34	GO:0043233	organelle lumen
0.33	GO:0043234	protein complex
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.32

GO:0016787

sp|O08796|EF2K_MOUSE
Eukaryotic elongation factor 2 kinase
Search

EEF2K

0.95	Eukaryotic elongation factor 2 kinase

0.62	GO:0006468	protein phosphorylation
0.62	GO:0006414	translational elongation
0.59	GO:0031952	regulation of protein autophosphorylation
0.41	GO:1990637	response to prolactin
0.41	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus
0.40	GO:0061003	positive regulation of dendritic spine morphogenesis
0.40	GO:0071454	cellular response to anoxia
0.40	GO:0002931	response to ischemia
0.40	GO:0071320	cellular response to cAMP
0.40	GO:0071277	cellular response to calcium ion

0.86	GO:0004686	elongation factor-2 kinase activity
0.77	GO:0005516	calmodulin binding
0.68	GO:0005509	calcium ion binding
0.62	GO:0003746	translation elongation factor activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0005737	cytoplasm
0.39	GO:0043197	dendritic spine
0.39	GO:0014069	postsynaptic density

0.86

EC:2.7.11.20

GO:0004686

tr|O08797|O08797_MOUSE
Putative uncharacterized protein
Search

0.97	Cytoplasmic antiproteinase 3

0.66	GO:0010951	negative regulation of endopeptidase activity
0.53	GO:0042270	protection from natural killer cell mediated cytotoxicity
0.51	GO:0033668	negative regulation by symbiont of host apoptotic process
0.51	GO:0002448	mast cell mediated immunity
0.50	GO:0071391	cellular response to estrogen stimulus
0.49	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.47	GO:0043066	negative regulation of apoptotic process
0.47	GO:0006915	apoptotic process
0.47	GO:0009617	response to bacterium
0.46	GO:0006955	immune response

0.68	GO:0004867	serine-type endopeptidase inhibitor activity
0.51	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.50	GO:0002020	protease binding
0.33	GO:0008233	peptidase activity

0.73	GO:0005615	extracellular space
0.47	GO:0005829	cytosol
0.45	GO:0005794	Golgi apparatus
0.44	GO:0005654	nucleoplasm
0.38	GO:1903561	extracellular vesicle
0.37	GO:0097180	serine protease inhibitor complex
0.35	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0070821	tertiary granule membrane
0.34	GO:0031012	extracellular matrix
0.32	GO:0005886	plasma membrane

0.33

GO:0008233

sp|O08800|SPB8_MOUSE
Serpin B8
Search

SERPINB8

0.97	Serpin peptidase inhibitor, clade B (Ovalbumin), member 8

0.61	GO:0010951	negative regulation of endopeptidase activity
0.55	GO:0090136	epithelial cell-cell adhesion
0.49	GO:0042270	protection from natural killer cell mediated cytotoxicity
0.47	GO:0002448	mast cell mediated immunity
0.47	GO:0033668	negative regulation by symbiont of host apoptotic process
0.47	GO:0071391	cellular response to estrogen stimulus
0.45	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.44	GO:0043066	negative regulation of apoptotic process
0.44	GO:0006915	apoptotic process
0.44	GO:0009617	response to bacterium

0.63	GO:0004867	serine-type endopeptidase inhibitor activity
0.47	GO:0002020	protease binding
0.47	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.32	GO:0016740	transferase activity

0.69	GO:0005615	extracellular space
0.50	GO:0005829	cytosol
0.43	GO:0005794	Golgi apparatus
0.42	GO:0005654	nucleoplasm
0.39	GO:1903561	extracellular vesicle
0.38	GO:0097180	serine protease inhibitor complex
0.36	GO:0101003	ficolin-1-rich granule membrane
0.36	GO:0070821	tertiary granule membrane
0.35	GO:0031012	extracellular matrix
0.33	GO:0005886	plasma membrane

0.32

GO:0016740

tr|O08804|O08804_MOUSE
NK13
Search

0.95	Serpin peptidase inhibitor, clade B (Ovalbumin), member 6

0.59	GO:0010951	negative regulation of endopeptidase activity
0.44	GO:0042270	protection from natural killer cell mediated cytotoxicity
0.43	GO:0002444	myeloid leukocyte mediated immunity
0.43	GO:0052490	negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction
0.43	GO:0071391	cellular response to estrogen stimulus
0.41	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.41	GO:0090136	epithelial cell-cell adhesion
0.40	GO:0043066	negative regulation of apoptotic process
0.40	GO:0052150	modulation by symbiont of host apoptotic process
0.40	GO:0006915	apoptotic process

0.61	GO:0004867	serine-type endopeptidase inhibitor activity
0.44	GO:0002020	protease binding
0.43	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process

0.73	GO:0005615	extracellular space
0.42	GO:0005829	cytosol
0.40	GO:0005794	Golgi apparatus
0.39	GO:0097180	serine protease inhibitor complex
0.39	GO:0005654	nucleoplasm
0.37	GO:1903561	extracellular vesicle
0.35	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0070821	tertiary granule membrane
0.33	GO:0031012	extracellular matrix
0.32	GO:0005886	plasma membrane

tr|O08806|O08806_MOUSE
MCG118183
Search

0.97	Cytoplasmic antiproteinase 3

0.65	GO:0010951	negative regulation of endopeptidase activity
0.53	GO:0042270	protection from natural killer cell mediated cytotoxicity
0.51	GO:0033668	negative regulation by symbiont of host apoptotic process
0.51	GO:0002448	mast cell mediated immunity
0.50	GO:0071391	cellular response to estrogen stimulus
0.49	GO:0043066	negative regulation of apoptotic process
0.49	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.48	GO:0090136	epithelial cell-cell adhesion
0.47	GO:0006915	apoptotic process
0.47	GO:0009617	response to bacterium

0.67	GO:0004867	serine-type endopeptidase inhibitor activity
0.51	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.50	GO:0002020	protease binding
0.33	GO:0008233	peptidase activity

0.73	GO:0005615	extracellular space
0.48	GO:0005829	cytosol
0.45	GO:0005794	Golgi apparatus
0.44	GO:0005654	nucleoplasm
0.39	GO:1903561	extracellular vesicle
0.38	GO:0097180	serine protease inhibitor complex
0.35	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0070821	tertiary granule membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

GO:0008233

sp|O08807|PRDX4_MOUSE
Peroxiredoxin-4
Search

PRDX4

0.43	Epididymis secretory sperm binding protein Li 97n

0.69	GO:0098869	cellular oxidant detoxification
0.68	GO:0045454	cell redox homeostasis
0.57	GO:2000255	negative regulation of male germ cell proliferation
0.57	GO:0022417	protein maturation by protein folding
0.56	GO:0019471	4-hydroxyproline metabolic process
0.54	GO:0008584	male gonad development
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0030198	extracellular matrix organization
0.52	GO:0007283	spermatogenesis
0.49	GO:0072593	reactive oxygen species metabolic process

0.73	GO:0051920	peroxiredoxin activity
0.50	GO:0042803	protein homodimerization activity
0.41	GO:0004601	peroxidase activity
0.34	GO:0004867	serine-type endopeptidase inhibitor activity

0.48	GO:0005783	endoplasmic reticulum
0.47	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.37	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.34	GO:0005634	nucleus

0.73	EC:1.11.1.15	GO:0051920
0.41	KEGG:R03532	GO:0004601

sp|O08808|DIAP1_MOUSE
Protein diaphanous homolog 1
Search

DIAPH1

0.92	Diaphanous homologue

0.82	GO:0030041	actin filament polymerization
0.61	GO:0071420	cellular response to histamine
0.59	GO:0035372	protein localization to microtubule
0.57	GO:0051279	regulation of release of sequestered calcium ion into cytosol
0.55	GO:0032886	regulation of microtubule-based process
0.53	GO:0051493	regulation of cytoskeleton organization
0.49	GO:0008360	regulation of cell shape
0.42	GO:0007292	female gamete generation
0.38	GO:0007605	sensory perception of sound
0.38	GO:0007420	brain development

0.77	GO:0017048	Rho GTPase binding
0.74	GO:0003779	actin binding
0.57	GO:0044325	ion channel binding
0.40	GO:0005522	profilin binding
0.37	GO:0042802	identical protein binding
0.34	GO:0005102	receptor binding
0.34	GO:0003723	RNA binding
0.32	GO:0030545	receptor regulator activity

0.55	GO:0072686	mitotic spindle
0.40	GO:0032587	ruffle membrane
0.39	GO:0005903	brush border
0.38	GO:0043005	neuron projection
0.37	GO:0005815	microtubule organizing center
0.36	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0005876	spindle microtubule
0.34	GO:0005730	nucleolus
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0005829	cytosol

sp|O08810|U5S1_MOUSE
116 kDa U5 small nuclear ribonucleoprotein component
Search

EFTUD2

0.79	Elongation factor Tu GTP-binding domain-containing 2

0.52	GO:0043010	camera-type eye development
0.52	GO:0006414	translational elongation
0.52	GO:0045664	regulation of neuron differentiation
0.51	GO:0060322	head development
0.51	GO:0048666	neuron development
0.50	GO:0000398	mRNA splicing, via spliceosome
0.38	GO:0042220	response to cocaine
0.37	GO:0035690	cellular response to drug

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0003746	translation elongation factor activity

0.66	GO:0071007	U2-type catalytic step 2 spliceosome
0.65	GO:0015030	Cajal body
0.62	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.62	GO:0016607	nuclear speck
0.54	GO:0005829	cytosol
0.36	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

sp|O08811|ERCC2_MOUSE
TFIIH basal transcription factor complex helicase XPD subunit
Search

ERCC2

0.93	General transcription and DNA repair factor IIH helicase subunit XPD

0.73	GO:0006289	nucleotide-excision repair
0.70	GO:0032508	DNA duplex unwinding
0.52	GO:0032289	central nervous system myelin formation
0.51	GO:0035315	hair cell differentiation
0.51	GO:0009650	UV protection
0.51	GO:0048820	hair follicle maturation
0.50	GO:0040016	embryonic cleavage
0.50	GO:0043249	erythrocyte maturation
0.50	GO:0060218	hematopoietic stem cell differentiation
0.49	GO:0030282	bone mineralization

0.72	GO:0004003	ATP-dependent DNA helicase activity
0.55	GO:0030554	adenyl nucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0047485	protein N-terminus binding
0.50	GO:0043139	5'-3' DNA helicase activity
0.50	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.50	GO:0008022	protein C-terminus binding

0.61	GO:0005634	nucleus
0.53	GO:0071817	MMXD complex
0.51	GO:0150005	enzyme activator complex
0.50	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.48	GO:0000428	DNA-directed RNA polymerase complex
0.47	GO:0005667	transcription factor complex
0.45	GO:0070013	intracellular organelle lumen
0.44	GO:0005829	cytosol
0.38	GO:0005703	polytene chromosome puff
0.37	GO:0005705	polytene chromosome interband

0.50

EC:2.7.11.23

GO:0008353

sp|O08832|GALT4_MOUSE
Polypeptide N-acetylgalactosaminyltransferase 4
Search

0.64	Polypeptide N-acetylgalactosaminyltransferase

0.72	GO:0043413	macromolecule glycosylation
0.72	GO:0009101	glycoprotein biosynthetic process
0.59	GO:0006464	cellular protein modification process
0.33	GO:0005975	carbohydrate metabolic process

0.68	GO:0030246	carbohydrate binding
0.64	GO:0016757	transferase activity, transferring glycosyl groups
0.35	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0046872	metal ion binding

0.72	GO:0000139	Golgi membrane
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.64

GO:0016757

sp|O08842|GFRA2_MOUSE
GDNF family receptor alpha-2
Search

GFRA2

0.97	GDNF family receptor alpha

0.50	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.50	GO:0007399	nervous system development
0.46	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.38	GO:0031953	negative regulation of protein autophosphorylation
0.36	GO:0120036	plasma membrane bounded cell projection organization
0.36	GO:0048468	cell development
0.36	GO:0000165	MAPK cascade
0.36	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.35	GO:0006928	movement of cell or subcellular component
0.35	GO:0040011	locomotion

0.65	GO:0004872	receptor activity
0.36	GO:0004871	signal transducer activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0005102	receptor binding
0.34	GO:0050839	cell adhesion molecule binding
0.33	GO:0032403	protein complex binding

0.70	GO:0031225	anchored component of membrane
0.51	GO:0005886	plasma membrane
0.35	GO:0019898	extrinsic component of membrane
0.35	GO:0070062	extracellular exosome
0.34	GO:0043025	neuronal cell body
0.34	GO:0030424	axon
0.33	GO:0043235	receptor complex
0.33	GO:0009986	cell surface
0.33	GO:0098552	side of membrane
0.32	GO:0098796	membrane protein complex

sp|O08843|LST1_MOUSE
Leukocyte-specific transcript 1 protein
Search

LST1

0.97	Leukocyte specific transcript 1

0.75	GO:0000902	cell morphogenesis
0.74	GO:0006955	immune response
0.64	GO:0016358	dendrite development
0.64	GO:0050670	regulation of lymphocyte proliferation
0.63	GO:0032945	negative regulation of mononuclear cell proliferation
0.62	GO:0051250	negative regulation of lymphocyte activation
0.43	GO:0008360	regulation of cell shape
0.37	GO:0007229	integrin-mediated signaling pathway
0.36	GO:0007155	cell adhesion

0.41	GO:0005737	cytoplasm
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0031984	organelle subcompartment
0.37	GO:0012505	endomembrane system
0.37	GO:0008305	integrin complex
0.35	GO:0043231	intracellular membrane-bounded organelle

sp|O08848|RO60_MOUSE
60 kDa SS-A/Ro ribonucleoprotein
Search

TROVE2

0.93	Sjogren syndrome antigen A2 (60kDa, ribonucleoprotein autoantigen SS-A/Ro)

0.56	GO:0007224	smoothened signaling pathway
0.55	GO:0009411	response to UV
0.54	GO:0060271	cilium assembly
0.52	GO:0002520	immune system development
0.35	GO:0006383	transcription by RNA polymerase III
0.33	GO:0006508	proteolysis
0.31	GO:0055114	oxidation-reduction process

0.59	GO:0030620	U2 snRNA binding
0.39	GO:0034336	misfolded RNA binding
0.34	GO:0046872	metal ion binding
0.33	GO:0008233	peptidase activity
0.31	GO:0016491	oxidoreductase activity

0.59	GO:0019013	viral nucleocapsid
0.56	GO:0030529	intracellular ribonucleoprotein complex
0.50	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008233

sp|O08849|RGS2_MOUSE
Regulator of G-protein signaling 2
Search

RGS2

0.97	Regulator of G-protein signaling protein 2

0.80	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway
0.74	GO:0043547	positive regulation of GTPase activity
0.63	GO:0010519	negative regulation of phospholipase activity
0.63	GO:0071877	regulation of adrenergic receptor signaling pathway
0.62	GO:0060087	relaxation of vascular smooth muscle
0.62	GO:0060452	positive regulation of cardiac muscle contraction
0.62	GO:0055119	relaxation of cardiac muscle
0.62	GO:0010614	negative regulation of cardiac muscle hypertrophy
0.61	GO:0043951	negative regulation of cAMP-mediated signaling
0.59	GO:0050873	brown fat cell differentiation

0.74	GO:0005096	GTPase activator activity
0.61	GO:0001965	G-protein alpha-subunit binding
0.41	GO:0048487	beta-tubulin binding
0.35	GO:0005516	calmodulin binding

0.54	GO:0009898	cytoplasmic side of plasma membrane
0.51	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.39	GO:0043005	neuron projection
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0044446	intracellular organelle part
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

sp|O08850|RGS5_MOUSE
Regulator of G-protein signaling 5
Search

RGS5

0.96	Regulator of G-protein signaling 5

0.64	GO:0043547	positive regulation of GTPase activity
0.51	GO:0007186	G-protein coupled receptor signaling pathway
0.47	GO:0009968	negative regulation of signal transduction
0.43	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.36	GO:0007601	visual perception

0.65	GO:0005096	GTPase activator activity
0.36	GO:0005516	calmodulin binding

0.61	GO:0005829	cytosol
0.47	GO:0005886	plasma membrane
0.36	GO:0045121	membrane raft
0.30	GO:0031224	intrinsic component of membrane

sp|O08852|PKD1_MOUSE
Polycystin-1
Search

PKD1

0.85	Polycystin 1, transient receptor potential channel interacting

0.81	GO:0001822	kidney development
0.60	GO:0036303	lymph vessel morphogenesis
0.60	GO:0031659	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
0.60	GO:0042994	cytoplasmic sequestering of transcription factor
0.59	GO:0001502	cartilage condensation
0.59	GO:0034405	response to fluid shear stress
0.58	GO:0060428	lung epithelium development
0.58	GO:0001889	liver development
0.58	GO:0050982	detection of mechanical stimulus
0.58	GO:0006611	protein export from nucleus

0.57	GO:0044325	ion channel binding
0.55	GO:0005262	calcium channel activity
0.54	GO:0019901	protein kinase binding
0.53	GO:0019904	protein domain specific binding
0.41	GO:0030246	carbohydrate binding

0.61	GO:0002133	polycystin complex
0.56	GO:0016323	basolateral plasma membrane
0.55	GO:0070062	extracellular exosome
0.54	GO:0031514	motile cilium
0.52	GO:0009986	cell surface
0.45	GO:0005634	nucleus
0.45	GO:0016328	lateral plasma membrane
0.41	GO:0005794	Golgi apparatus
0.40	GO:0060170	ciliary membrane
0.39	GO:0030660	Golgi-associated vesicle membrane

sp|O08856|ELL_MOUSE
RNA polymerase II elongation factor ELL
Search

ELL

0.94	RNA polymerase II elongation factor ELL

0.86	GO:0042795	snRNA transcription by RNA polymerase II
0.80	GO:0006368	transcription elongation from RNA polymerase II promoter
0.60	GO:0006414	translational elongation
0.58	GO:0042796	snRNA transcription by RNA polymerase III
0.57	GO:0045945	positive regulation of transcription by RNA polymerase III
0.54	GO:0010923	negative regulation of phosphatase activity
0.54	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.52	GO:0001701	in utero embryonic development
0.44	GO:0001570	vasculogenesis

0.61	GO:0003746	translation elongation factor activity
0.54	GO:0019902	phosphatase binding

0.79	GO:0008023	transcription elongation factor complex
0.58	GO:0035363	histone locus body
0.56	GO:0015030	Cajal body
0.56	GO:0035327	transcriptionally active chromatin
0.53	GO:0016607	nuclear speck
0.30	GO:0016020	membrane

sp|O08858|SSR5_MOUSE
Somatostatin receptor type 5
Search

SSTR5

0.97	Somatostatin receptor subtype 5

0.86	GO:0038170	somatostatin signaling pathway
0.54	GO:0090276	regulation of peptide hormone secretion
0.54	GO:0032467	positive regulation of cytokinesis
0.52	GO:0050708	regulation of protein secretion
0.51	GO:0042593	glucose homeostasis
0.49	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.48	GO:0071385	cellular response to glucocorticoid stimulus
0.47	GO:0007268	chemical synaptic transmission
0.45	GO:0008285	negative regulation of cell proliferation
0.41	GO:0007218	neuropeptide signaling pathway

0.86	GO:0004994	somatostatin receptor activity
0.51	GO:0042923	neuropeptide binding
0.43	GO:0005102	receptor binding

0.49	GO:0120025	plasma membrane bounded cell projection
0.46	GO:0097458	neuron part
0.44	GO:0005886	plasma membrane
0.42	GO:0098588	bounding membrane of organelle
0.42	GO:0044463	cell projection part
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|O08859|TSG6_MOUSE
Tumor necrosis factor-inducible gene 6 protein
Search

TNFAIP6

0.97	Tumor necrosis factor alpha induced protein 6

0.72	GO:0007155	cell adhesion
0.60	GO:0050728	negative regulation of inflammatory response
0.43	GO:0030728	ovulation
0.41	GO:0030335	positive regulation of cell migration
0.36	GO:0007267	cell-cell signaling
0.36	GO:0006952	defense response
0.36	GO:0043312	neutrophil degranulation
0.35	GO:0016525	negative regulation of angiogenesis
0.35	GO:0009617	response to bacterium
0.34	GO:0006898	receptor-mediated endocytosis

0.84	GO:0005540	hyaluronic acid binding
0.38	GO:0005509	calcium ion binding
0.36	GO:0005041	low-density lipoprotein receptor activity
0.36	GO:0030169	low-density lipoprotein particle binding
0.35	GO:0005044	scavenger receptor activity
0.33	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0004222	metalloendopeptidase activity
0.32	GO:0008270	zinc ion binding

0.39	GO:0005615	extracellular space
0.36	GO:1904724	tertiary granule lumen
0.36	GO:1904813	ficolin-1-rich granule lumen
0.34	GO:0005887	integral component of plasma membrane
0.33	GO:0005840	ribosome

0.32

GO:0004222

sp|O08863|BIRC3_MOUSE
Baculoviral IAP repeat-containing protein 3
Search

0.89	Inhibitor of apoptosis protein (Fragment)

0.74	GO:0042981	regulation of apoptotic process
0.42	GO:0060546	negative regulation of necroptotic process
0.42	GO:0097340	inhibition of cysteine-type endopeptidase activity
0.41	GO:0034121	regulation of toll-like receptor signaling pathway
0.41	GO:0090307	mitotic spindle assembly
0.39	GO:0006915	apoptotic process
0.38	GO:0016567	protein ubiquitination

0.42	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.39	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0046872	metal ion binding

0.36	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm

0.39

GO:0004842

sp|O08884|KRA62_MOUSE
Keratin-associated protein 6-2
Search

0.71	Keratin-associated protein 6-2

0.49	GO:0016560	protein import into peroxisome matrix, docking
0.49	GO:0043480	pigment accumulation in tissues
0.48	GO:0031077	post-embryonic camera-type eye development
0.46	GO:0001942	hair follicle development
0.46	GO:0070830	bicellular tight junction assembly
0.44	GO:0048589	developmental growth
0.44	GO:0008283	cell proliferation
0.44	GO:0007020	microtubule nucleation
0.42	GO:0051726	regulation of cell cycle
0.39	GO:0007165	signal transduction

0.44	GO:0043015	gamma-tubulin binding
0.42	GO:0030674	protein binding, bridging
0.39	GO:0005198	structural molecule activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003676	nucleic acid binding

0.63	GO:0005882	intermediate filament
0.46	GO:0005777	peroxisome
0.44	GO:0005923	bicellular tight junction
0.44	GO:1990429	peroxisomal importomer complex
0.43	GO:0000922	spindle pole
0.42	GO:0005815	microtubule organizing center
0.42	GO:0031903	microbody membrane
0.30	GO:0016021	integral component of membrane

sp|O08899|RGS4_MOUSE
Regulator of G-protein signaling 4
Search

RGS4

0.97	LOW QUALITY PROTEIN: regulator of G-protein signaling 4

0.71	GO:0043547	positive regulation of GTPase activity
0.65	GO:0007186	G-protein coupled receptor signaling pathway
0.49	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.44	GO:0009968	negative regulation of signal transduction
0.36	GO:0031018	endocrine pancreas development
0.36	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.36	GO:0043405	regulation of MAP kinase activity
0.35	GO:0007626	locomotory behavior
0.35	GO:0007409	axonogenesis
0.34	GO:0010519	negative regulation of phospholipase activity

0.72	GO:0005096	GTPase activator activity
0.41	GO:0001965	G-protein alpha-subunit binding
0.35	GO:0005516	calmodulin binding

0.46	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.39	GO:0005886	plasma membrane
0.35	GO:0043234	protein complex
0.35	GO:0098562	cytoplasmic side of membrane
0.34	GO:0019898	extrinsic component of membrane
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part

sp|O08900|IKZF3_MOUSE
Zinc finger protein Aiolos
Search

IKZF3

0.95	Zinc finger protein Aiolos

0.48	GO:0045577	regulation of B cell differentiation
0.48	GO:0030888	regulation of B cell proliferation
0.45	GO:0042113	B cell activation
0.44	GO:0045944	positive regulation of transcription by RNA polymerase II
0.44	GO:0042981	regulation of apoptotic process
0.43	GO:0006366	transcription by RNA polymerase II
0.39	GO:0007498	mesoderm development

0.51	GO:0003676	nucleic acid binding
0.44	GO:0042803	protein homodimerization activity
0.44	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.44	GO:0046982	protein heterodimerization activity
0.37	GO:0046872	metal ion binding

0.41	GO:0005654	nucleoplasm
0.41	GO:0005829	cytosol
0.37	GO:0005886	plasma membrane

sp|O08901|BUB1_MOUSE
Mitotic checkpoint serine/threonine-protein kinase BUB1
Search

BUB1

0.83	Mitotic checkpoint serine/threonine-protein kinase BUB1

0.83	GO:0007094	mitotic spindle assembly checkpoint
0.62	GO:0006468	protein phosphorylation
0.60	GO:0007063	regulation of sister chromatid cohesion
0.54	GO:0051754	meiotic sister chromatid cohesion, centromeric
0.43	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.42	GO:0008283	cell proliferation
0.39	GO:0006915	apoptotic process
0.37	GO:0051301	cell division
0.35	GO:0031134	sister chromatid biorientation
0.35	GO:0034501	protein localization to kinetochore

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0042802	identical protein binding
0.32	GO:0003899	DNA-directed 5'-3' RNA polymerase activity

0.59	GO:0000778	condensed nuclear chromosome kinetochore
0.57	GO:0000940	condensed chromosome outer kinetochore
0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.32

GO:0003899

sp|O08908|P85B_MOUSE
Phosphatidylinositol 3-kinase regulatory subunit beta
Search

PIK3R2

0.86	Phosphatidylinositol 3-kinase regulatory subunit alpha

0.83	GO:0043551	regulation of phosphatidylinositol 3-kinase activity
0.58	GO:0007165	signal transduction
0.55	GO:0016310	phosphorylation
0.53	GO:2001275	positive regulation of glucose import in response to insulin stimulus
0.51	GO:0042993	positive regulation of transcription factor import into nucleus
0.51	GO:0071375	cellular response to peptide hormone stimulus
0.50	GO:0032868	response to insulin
0.48	GO:0034976	response to endoplasmic reticulum stress
0.48	GO:1903076	regulation of protein localization to plasma membrane
0.48	GO:0051492	regulation of stress fiber assembly

0.84	GO:0035014	phosphatidylinositol 3-kinase regulator activity
0.56	GO:0016301	kinase activity
0.50	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding
0.47	GO:0001784	phosphotyrosine residue binding
0.46	GO:0019903	protein phosphatase binding
0.45	GO:0008134	transcription factor binding
0.45	GO:0046982	protein heterodimerization activity
0.44	GO:0043125	ErbB-3 class receptor binding
0.44	GO:0043559	insulin binding
0.44	GO:0005168	neurotrophin TRKA receptor binding

0.81	GO:0005942	phosphatidylinositol 3-kinase complex
0.44	GO:0030054	cell junction
0.41	GO:1990578	perinuclear endoplasmic reticulum membrane
0.41	GO:0005634	nucleus
0.39	GO:0005829	cytosol
0.39	GO:0005801	cis-Golgi network
0.35	GO:0043234	protein complex

0.34

GO:0016773

sp|O08911|MK12_MOUSE
Mitogen-activated protein kinase 12
Search

MAPK12

0.58	Mitogen-activated protein kinase

0.79	GO:0000165	MAPK cascade
0.56	GO:0045445	myoblast differentiation
0.55	GO:0018105	peptidyl-serine phosphorylation
0.41	GO:0032755	positive regulation of interleukin-6 production
0.40	GO:0006970	response to osmotic stress
0.39	GO:0010468	regulation of gene expression
0.37	GO:0045786	negative regulation of cell cycle
0.36	GO:0007049	cell cycle
0.36	GO:0006975	DNA damage induced protein phosphorylation
0.35	GO:0006351	transcription, DNA-templated

0.81	GO:0004707	MAP kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0000287	magnesium ion binding
0.34	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.36	GO:0031974	membrane-enclosed lumen
0.34	GO:0044422	organelle part

0.81	EC:2.7.11.24	GO:0004707
0.81	KEGG:R00162	GO:0004707

sp|O08912|GALT1_MOUSE
Polypeptide N-acetylgalactosaminyltransferase 1
Search

GALNT1

0.64	Polypeptide N-acetylgalactosaminyltransferase

0.73	GO:0043413	macromolecule glycosylation
0.73	GO:0009101	glycoprotein biosynthetic process
0.59	GO:0036211	protein modification process
0.55	GO:0044267	cellular protein metabolic process

0.69	GO:0030246	carbohydrate binding
0.64	GO:0016757	transferase activity, transferring glycosyl groups
0.49	GO:0030145	manganese ion binding
0.45	GO:0140096	catalytic activity, acting on a protein

0.73	GO:0000139	Golgi membrane
0.51	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0031985	Golgi cisterna
0.37	GO:0005576	extracellular region
0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.64

GO:0016757

sp|O08914|FAAH1_MOUSE
Fatty-acid amide hydrolase 1
Search

FAAH

0.80	Fatty acid amide hydrolase

0.53	GO:0009062	fatty acid catabolic process
0.36	GO:0097756	negative regulation of blood vessel diameter
0.36	GO:0019369	arachidonic acid metabolic process

0.81	GO:0017064	fatty acid amide hydrolase activity
0.72	GO:0004040	amidase activity
0.57	GO:0047372	acylglycerol lipase activity
0.44	GO:0103073	anandamide amidohydrolase activity
0.44	GO:0102077	oleamide hydrolase activity
0.35	GO:0005515	protein binding
0.35	GO:0005543	phospholipid binding

0.39	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0000139	Golgi membrane
0.34	GO:0005856	cytoskeleton
0.30	GO:0016021	integral component of membrane

0.72

EC:3.5.1.4

GO:0004040

sp|O08915|AIP_MOUSE
AH receptor-interacting protein
Search

AIP

0.71	AH receptor-interacting protein isoform 1

0.81	GO:0022417	protein maturation by protein folding
0.75	GO:0006805	xenobiotic metabolic process
0.73	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity
0.70	GO:0006626	protein targeting to mitochondrion
0.66	GO:0010738	regulation of protein kinase A signaling
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:0035722	interleukin-12-mediated signaling pathway

0.84	GO:0036004	GAF domain binding
0.83	GO:0017162	aryl hydrocarbon receptor binding
0.73	GO:0003712	transcription cofactor activity
0.64	GO:0051082	unfolded protein binding
0.43	GO:0004871	signal transducer activity

0.79	GO:0034751	aryl hydrocarbon receptor complex
0.63	GO:0005829	cytosol
0.51	GO:0005886	plasma membrane
0.45	GO:0005654	nucleoplasm

sp|O08917|FLOT1_MOUSE
Flotillin-1
Search

FLOT1

0.90	Novel flotillin

0.85	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin
0.85	GO:0060355	positive regulation of cell adhesion molecule production
0.84	GO:0032226	positive regulation of synaptic transmission, dopaminergic
0.84	GO:0070528	protein kinase C signaling
0.83	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway
0.83	GO:1903044	protein localization to membrane raft
0.83	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.83	GO:1901741	positive regulation of myoblast fusion
0.82	GO:0071360	cellular response to exogenous dsRNA
0.82	GO:0048643	positive regulation of skeletal muscle tissue development

0.78	GO:0002020	protease binding
0.68	GO:0046982	protein heterodimerization activity
0.52	GO:0035255	ionotropic glutamate receptor binding

0.83	GO:0016600	flotillin complex
0.82	GO:0001931	uropod
0.80	GO:0034451	centriolar satellite
0.78	GO:0044291	cell-cell contact zone
0.77	GO:0042383	sarcolemma
0.76	GO:0005913	cell-cell adherens junction
0.76	GO:0030027	lamellipodium
0.75	GO:0016323	basolateral plasma membrane
0.74	GO:0008180	COP9 signalosome
0.74	GO:0030864	cortical actin cytoskeleton

sp|O08918|CCNG2_MOUSE
Cyclin-G2
Search

0.73	GO:0051726	regulation of cell cycle
0.35	GO:0051301	cell division
0.35	GO:0007049	cell cycle

0.34	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.34	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.34

EC:2.8.2.8

GO:0015016

sp|O08919|NUMBL_MOUSE
Numb-like protein
Search

NUMBL

0.91	Numb homolog (Drosophila)

0.83	GO:0021849	neuroblast division in subventricular zone
0.79	GO:0021670	lateral ventricle development
0.75	GO:0034332	adherens junction organization
0.71	GO:0050769	positive regulation of neurogenesis
0.70	GO:0007409	axonogenesis
0.68	GO:0019221	cytokine-mediated signaling pathway
0.64	GO:0060319	primitive erythrocyte differentiation
0.54	GO:0045746	negative regulation of Notch signaling pathway
0.53	GO:0007368	determination of left/right symmetry
0.48	GO:0019538	protein metabolic process

0.43	GO:0005515	protein binding
0.33	GO:0016301	kinase activity

0.52	GO:0016323	basolateral plasma membrane
0.48	GO:0005737	cytoplasm
0.41	GO:0045177	apical part of cell
0.40	GO:0019897	extrinsic component of plasma membrane
0.39	GO:0097708	intracellular vesicle
0.38	GO:0012505	endomembrane system
0.37	GO:0005634	nucleus

sp|O08934|UNC4_MOUSE
Homeobox protein unc-4 homolog
Search

UNCX

0.85	Homeobox protein unc-4

0.58	GO:0035726	common myeloid progenitor cell proliferation
0.57	GO:0021889	olfactory bulb interneuron differentiation
0.56	GO:0001502	cartilage condensation
0.56	GO:0021516	dorsal spinal cord development
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.52	GO:0007389	pattern specification process
0.51	GO:0045595	regulation of cell differentiation
0.37	GO:0006351	transcription, DNA-templated

0.62	GO:0043565	sequence-specific DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.33	GO:0030424	axon
0.33	GO:0045202	synapse
0.30	GO:0016020	membrane

sp|O08966|S22A1_MOUSE
Solute carrier family 22 member 1
Search

SLC22A1

0.96	Solute carrier family 22 member 1 isoform a

0.58	GO:0015695	organic cation transport
0.56	GO:0015872	dopamine transport
0.56	GO:0015874	norepinephrine transport
0.55	GO:0055085	transmembrane transport
0.55	GO:1901374	acetate ester transport
0.48	GO:0006836	neurotransmitter transport
0.46	GO:0015711	organic anion transport
0.41	GO:0048241	epinephrine transport
0.38	GO:0051260	protein homooligomerization
0.35	GO:0007589	body fluid secretion

0.60	GO:0015101	organic cation transmembrane transporter activity
0.56	GO:0005329	dopamine transmembrane transporter activity
0.56	GO:0005333	norepinephrine transmembrane transporter activity
0.55	GO:1901375	acetate ester transmembrane transporter activity
0.49	GO:0005326	neurotransmitter transporter activity
0.47	GO:0008514	organic anion transmembrane transporter activity
0.45	GO:0015291	secondary active transmembrane transporter activity
0.37	GO:0042803	protein homodimerization activity
0.34	GO:0005496	steroid binding

0.46	GO:0005887	integral component of plasma membrane
0.42	GO:0016323	basolateral plasma membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0098793	presynapse

sp|O08967|CYH3_MOUSE
Cytohesin-3
Search

CYTH3

0.96	Putative pattern-formation protein/guanine nucleotide exchange factor (Fragment)

0.81	GO:0032012	regulation of ARF protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.53	GO:0090162	establishment of epithelial cell polarity
0.49	GO:0030155	regulation of cell adhesion
0.49	GO:0048193	Golgi vesicle transport
0.46	GO:0048518	positive regulation of biological process

0.82	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.54	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding

0.52	GO:0001726	ruffle
0.51	GO:0005923	bicellular tight junction
0.50	GO:0005912	adherens junction
0.50	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.46	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol
0.34	GO:0000139	Golgi membrane

sp|O08969|PHLA2_MOUSE
Pleckstrin homology-like domain family A member 2
Search

PHLDA2

0.97	Pleckstrin homology like domain family A member 2

0.86	GO:1903547	regulation of growth hormone activity
0.85	GO:0060721	regulation of spongiotrophoblast cell proliferation
0.80	GO:0070873	regulation of glycogen metabolic process
0.75	GO:0001890	placenta development
0.73	GO:0030334	regulation of cell migration
0.71	GO:0009887	animal organ morphogenesis
0.53	GO:0010468	regulation of gene expression
0.43	GO:0006915	apoptotic process
0.41	GO:0045210	FasL biosynthetic process
0.40	GO:0051898	negative regulation of protein kinase B signaling

0.40	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.40	GO:0010314	phosphatidylinositol-5-phosphate binding
0.40	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.40	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.40	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.39	GO:0032266	phosphatidylinositol-3-phosphate binding

0.41	GO:0005737	cytoplasm
0.37	GO:0005730	nucleolus
0.35	GO:0005886	plasma membrane

sp|O08970|TUFT1_MOUSE
Tuftelin
Search

TUFT1

0.96

Tuftelin

0.50	GO:0031214	biomineral tissue development
0.41	GO:0042476	odontogenesis
0.40	GO:0001503	ossification
0.37	GO:0016197	endosomal transport
0.36	GO:0006886	intracellular protein transport
0.34	GO:0007165	signal transduction

0.42	GO:0030345	structural constituent of tooth enamel
0.41	GO:0005515	protein binding
0.37	GO:0032266	phosphatidylinositol-3-phosphate binding

0.48	GO:0005737	cytoplasm
0.43	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|O08976|PBAS_MOUSE
Probasin
Search

PBSN

0.97

Probasin

0.51

GO:0036094

small molecule binding

0.54	GO:0005576	extracellular region
0.40	GO:0005634	nucleus

sp|O08983|HPS1_MOUSE
Hermansky-Pudlak syndrome 1 protein homolog
Search

HPS1

0.95	Hermansky-Pudlak syndrome 1

0.87	GO:1903232	melanosome assembly
0.66	GO:0065009	regulation of molecular function
0.51	GO:0033299	secretion of lysosomal enzymes
0.50	GO:0032816	positive regulation of natural killer cell activation
0.50	GO:0048069	eye pigmentation
0.50	GO:0030318	melanocyte differentiation
0.48	GO:0060041	retina development in camera-type eye
0.48	GO:0007596	blood coagulation
0.40	GO:0007040	lysosome organization
0.39	GO:0007601	visual perception

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.67	GO:0046983	protein dimerization activity

0.87	GO:0031085	BLOC-3 complex
0.71	GO:0031410	cytoplasmic vesicle
0.39	GO:0005764	lysosome
0.37	GO:0005887	integral component of plasma membrane

sp|O08989|RASM_MOUSE
Ras-related protein M-Ras
Search

MRAS

0.97	Muscle RAS oncogene homolog

0.61	GO:0007165	signal transduction
0.54	GO:1990830	cellular response to leukemia inhibitory factor
0.37	GO:0061817	endoplasmic reticulum-plasma membrane tethering
0.36	GO:0006869	lipid transport
0.34	GO:0007517	muscle organ development
0.34	GO:0030036	actin cytoskeleton organization
0.34	GO:0043066	negative regulation of apoptotic process

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.58	GO:0030742	GTP-dependent protein binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0008289	lipid binding

0.36	GO:0070062	extracellular exosome
0.34	GO:0005886	plasma membrane
0.32	GO:0005622	intracellular

sp|O08992|SDCB1_MOUSE
Syntenin-1
Search

SDCBP

0.93	Putative pdz domain containing protein found in a variety of eumetazoan signaling molecules

0.78	GO:0007268	chemical synaptic transmission
0.74	GO:0030036	actin cytoskeleton organization
0.63	GO:0035556	intracellular signal transduction
0.52	GO:0030307	positive regulation of cell growth
0.51	GO:0030335	positive regulation of cell migration
0.50	GO:0008284	positive regulation of cell proliferation
0.43	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.42	GO:0042246	tissue regeneration
0.42	GO:0007416	synapse assembly
0.41	GO:0001666	response to hypoxia

0.56	GO:0005137	interleukin-5 receptor binding
0.47	GO:0045545	syndecan binding
0.44	GO:1902936	phosphatidylinositol bisphosphate binding
0.38	GO:0005109	frizzled binding
0.38	GO:0050839	cell adhesion molecule binding
0.38	GO:0042043	neurexin family protein binding
0.38	GO:0046875	ephrin receptor binding
0.38	GO:0047485	protein N-terminus binding
0.38	GO:0008022	protein C-terminus binding
0.38	GO:0019838	growth factor binding

0.57	GO:0005895	interleukin-5 receptor complex
0.52	GO:0031965	nuclear membrane
0.47	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome
0.38	GO:0042470	melanosome
0.37	GO:0005925	focal adhesion
0.37	GO:0098857	membrane microdomain
0.37	GO:0072562	blood microparticle
0.36	GO:0005789	endoplasmic reticulum membrane

sp|O08997|ATOX1_MOUSE
Copper transport protein ATOX1
Search

ATOX1

0.94	Copper transport protein ATOX1

0.66	GO:0030001	metal ion transport
0.46	GO:0006878	cellular copper ion homeostasis
0.41	GO:0006979	response to oxidative stress
0.41	GO:0046907	intracellular transport
0.37	GO:0098662	inorganic cation transmembrane transport
0.37	GO:0019730	antimicrobial humoral response

0.54	GO:0046872	metal ion binding
0.51	GO:0032767	copper-dependent protein binding
0.48	GO:0016530	metallochaperone activity
0.42	GO:0051117	ATPase binding
0.41	GO:0005375	copper ion transmembrane transporter activity
0.37	GO:0047760	butyrate-CoA ligase activity

0.37	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.37

EC:6.2.1.2

GO:0047760

sp|O08999|LTBP2_MOUSE
Latent-transforming growth factor beta-binding protein 2
Search

LTBP2

0.68	Latent transforming growth factor beta binding protein 2

0.53	GO:0097435	supramolecular fiber organization
0.38	GO:0060976	coronary vasculature development
0.38	GO:0035904	aorta development
0.38	GO:0003281	ventricular septum development
0.36	GO:0007179	transforming growth factor beta receptor signaling pathway
0.34	GO:0032940	secretion by cell
0.34	GO:0006605	protein targeting
0.34	GO:0002790	peptide secretion
0.34	GO:0009914	hormone transport
0.33	GO:0007267	cell-cell signaling

0.70	GO:0005509	calcium ion binding
0.40	GO:0019838	growth factor binding
0.39	GO:0050436	microfibril binding
0.38	GO:0019955	cytokine binding
0.37	GO:0008201	heparin binding
0.34	GO:0005201	extracellular matrix structural constituent

0.54	GO:0031012	extracellular matrix
0.53	GO:0005615	extracellular space
0.36	GO:0099512	supramolecular fiber
0.35	GO:1903561	extracellular vesicle
0.34	GO:0043234	protein complex
0.32	GO:0005622	intracellular

sp|O09000|NCOA3_MOUSE
Nuclear receptor coactivator 3
Search

NCOA3

0.97	Nuclear receptor coactivator 3

0.65	GO:0045618	positive regulation of keratinocyte differentiation
0.64	GO:0071392	cellular response to estradiol stimulus
0.58	GO:0016573	histone acetylation
0.57	GO:0045944	positive regulation of transcription by RNA polymerase II
0.57	GO:0006351	transcription, DNA-templated
0.48	GO:0030522	intracellular receptor signaling pathway
0.42	GO:1902459	positive regulation of stem cell population maintenance
0.41	GO:2000035	regulation of stem cell division
0.41	GO:0043697	cell dedifferentiation
0.40	GO:0060744	mammary gland branching involved in thelarche

0.85	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.83	GO:0035257	nuclear hormone receptor binding
0.67	GO:0046983	protein dimerization activity
0.63	GO:0097718	disordered domain specific binding
0.62	GO:0047485	protein N-terminus binding
0.59	GO:0004402	histone acetyltransferase activity
0.40	GO:0000993	RNA polymerase II core binding
0.39	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.38	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.55	GO:0000785	chromatin
0.52	GO:0005829	cytosol
0.52	GO:0031974	membrane-enclosed lumen
0.47	GO:0043234	protein complex
0.37	GO:0070062	extracellular exosome
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005794	Golgi apparatus

0.59

EC:2.3.1.48

GO:0004402

sp|O09005|DEGS1_MOUSE
Sphingolipid delta(4)-desaturase DES1
Search

DEGS1

0.93	Degenerative spermatocyte homolog 1, lipid desaturase

0.83	GO:0030148	sphingolipid biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.51	GO:0006672	ceramide metabolic process
0.42	GO:0043604	amide biosynthetic process
0.42	GO:0006667	sphinganine metabolic process
0.39	GO:0006633	fatty acid biosynthetic process
0.37	GO:0043065	positive regulation of apoptotic process
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0033559	unsaturated fatty acid metabolic process
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.85	GO:0042284	sphingolipid delta-4 desaturase activity
0.44	GO:0000170	sphingosine hydroxylase activity
0.34	GO:0004497	monooxygenase activity
0.34	GO:0016503	pheromone receptor activity
0.33	GO:0009055	electron transfer activity

0.44	GO:0005739	mitochondrion
0.40	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0035579	specific granule membrane
0.33	GO:0005887	integral component of plasma membrane

sp|O09008|MFNG_MOUSE
Beta-1,3-N-acetylglucosaminyltransferase manic fringe
Search

MFNG

0.85	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

0.67	GO:0007389	pattern specification process
0.63	GO:0036066	protein O-linked fucosylation
0.63	GO:0002315	marginal zone B cell differentiation
0.60	GO:0045747	positive regulation of Notch signaling pathway
0.60	GO:0032092	positive regulation of protein binding
0.48	GO:1902367	negative regulation of Notch signaling pathway involved in somitogenesis
0.46	GO:0051446	positive regulation of meiotic cell cycle
0.45	GO:0001541	ovarian follicle development
0.45	GO:0061053	somite development
0.45	GO:0030217	T cell differentiation

0.76	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity
0.46	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.32	GO:0016491	oxidoreductase activity

0.69	GO:0030173	integral component of Golgi membrane
0.35	GO:0044421	extracellular region part
0.34	GO:0031982	vesicle

0.76

EC:2.4.1.222

GO:0033829

sp|O09009|RFNG_MOUSE
Beta-1,3-N-acetylglucosaminyltransferase radical fringe
Search

RFNG

0.84	RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

0.69	GO:0007389	pattern specification process
0.57	GO:0036066	protein O-linked fucosylation
0.54	GO:0045747	positive regulation of Notch signaling pathway
0.54	GO:0032092	positive regulation of protein binding
0.44	GO:1902367	negative regulation of Notch signaling pathway involved in somitogenesis
0.43	GO:0030154	cell differentiation
0.43	GO:0048731	system development
0.42	GO:0002312	B cell activation involved in immune response
0.42	GO:0051446	positive regulation of meiotic cell cycle
0.42	GO:0009790	embryo development

0.79	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity
0.46	GO:0046872	metal ion binding
0.34	GO:0016491	oxidoreductase activity

0.71	GO:0030173	integral component of Golgi membrane
0.37	GO:1903561	extracellular vesicle
0.36	GO:0005615	extracellular space

0.79

EC:2.4.1.222

GO:0033829

sp|O09010|LFNG_MOUSE
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
Search

LFNG

0.83	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

0.69	GO:0007389	pattern specification process
0.58	GO:0036066	protein O-linked fucosylation
0.57	GO:1902367	negative regulation of Notch signaling pathway involved in somitogenesis
0.55	GO:0002315	marginal zone B cell differentiation
0.54	GO:0045747	positive regulation of Notch signaling pathway
0.54	GO:0032092	positive regulation of protein binding
0.53	GO:0051446	positive regulation of meiotic cell cycle
0.53	GO:0001541	ovarian follicle development
0.52	GO:0009790	embryo development
0.52	GO:0030217	T cell differentiation

0.79	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity
0.46	GO:0046872	metal ion binding
0.33	GO:0016491	oxidoreductase activity

0.70	GO:0030173	integral component of Golgi membrane
0.37	GO:1903561	extracellular vesicle

0.79

EC:2.4.1.222

GO:0033829

sp|O09012|PEX5_MOUSE
Peroxisomal targeting signal 1 receptor
Search

PEX5

0.92	Peroxisomal targeting signal 1 receptor

0.78	GO:0016558	protein import into peroxisome matrix
0.77	GO:0021895	cerebral cortex neuron differentiation
0.76	GO:0021795	cerebral cortex cell migration
0.75	GO:0040018	positive regulation of multicellular organism growth
0.74	GO:0050905	neuromuscular process
0.73	GO:0000038	very long-chain fatty acid metabolic process
0.73	GO:0001764	neuron migration
0.72	GO:0007029	endoplasmic reticulum organization
0.71	GO:0007006	mitochondrial membrane organization
0.68	GO:0006635	fatty acid beta-oxidation

0.71	GO:0005052	peroxisome matrix targeting signal-1 binding
0.50	GO:0008022	protein C-terminus binding
0.46	GO:0047485	protein N-terminus binding
0.43	GO:0031267	small GTPase binding

0.68	GO:0005829	cytosol
0.67	GO:0005794	Golgi apparatus
0.62	GO:0031903	microbody membrane
0.61	GO:0044439	peroxisomal part
0.54	GO:0005739	mitochondrion
0.52	GO:0031907	microbody lumen
0.39	GO:0043234	protein complex

sp|O09030|I13R1_MOUSE
Interleukin-13 receptor subunit alpha-1
Search

IL13RA1

0.97	Interleukin-13 receptor subunit alpha-1

0.78	GO:0019221	cytokine-mediated signaling pathway
0.44	GO:0035963	cellular response to interleukin-13
0.42	GO:0002639	positive regulation of immunoglobulin production
0.42	GO:0030890	positive regulation of B cell proliferation

0.80	GO:0004896	cytokine receptor activity
0.35	GO:0005515	protein binding

0.40

GO:0005898

interleukin-13 receptor complex

sp|O09035|DBIL5_MOUSE
Diazepam-binding inhibitor-like 5
Search

0.47	Phosphatidylserine decarboxylase

0.65	GO:0030242	autophagy of peroxisome
0.39	GO:0007283	spermatogenesis
0.38	GO:0036151	phosphatidylcholine acyl-chain remodeling
0.35	GO:0035973	aggrephagy
0.35	GO:0035383	thioester metabolic process
0.34	GO:0006732	coenzyme metabolic process
0.33	GO:0009062	fatty acid catabolic process
0.32	GO:0006508	proteolysis

0.82	GO:0000062	fatty-acyl-CoA binding
0.52	GO:0008289	lipid binding
0.35	GO:0046983	protein dimerization activity
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005777	peroxisome
0.42	GO:0005654	nucleoplasm
0.38	GO:0031903	microbody membrane
0.30	GO:0016021	integral component of membrane

0.33

GO:0004222

sp|O09037|REG3A_MOUSE
Regenerating islet-derived protein 3-alpha
Search

0.97	Pancreatic beta cell growth factor

0.67	GO:0044278	cell wall disruption in other organism
0.66	GO:0045617	negative regulation of keratinocyte differentiation
0.65	GO:0010838	positive regulation of keratinocyte proliferation
0.62	GO:0090303	positive regulation of wound healing
0.62	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.59	GO:0051715	cytolysis in other organism
0.58	GO:0006953	acute-phase response
0.58	GO:0050830	defense response to Gram-positive bacterium
0.56	GO:0050829	defense response to Gram-negative bacterium
0.50	GO:0002755	MyD88-dependent toll-like receptor signaling pathway

0.63	GO:0030246	carbohydrate binding
0.57	GO:0005539	glycosaminoglycan binding
0.51	GO:0042802	identical protein binding
0.40	GO:0001871	pattern binding
0.39	GO:0019838	growth factor binding
0.39	GO:1901681	sulfur compound binding
0.36	GO:0005509	calcium ion binding
0.35	GO:0043168	anion binding

0.51	GO:0005576	extracellular region
0.49	GO:0030141	secretory granule
0.41	GO:0044217	other organism part
0.39	GO:0045177	apical part of cell
0.35	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|O09039|SH2B3_MOUSE
SH2B adapter protein 3
Search

SH2B3

0.95	SH2B adapter protein 3

0.75	GO:0030097	hemopoiesis
0.75	GO:0009967	positive regulation of signal transduction
0.60	GO:0007165	signal transduction
0.53	GO:0048568	embryonic organ development
0.49	GO:0030154	cell differentiation
0.36	GO:0007596	blood coagulation
0.35	GO:0045589	regulation of regulatory T cell differentiation
0.35	GO:1903671	negative regulation of sprouting angiogenesis

0.83	GO:0035591	signaling adaptor activity
0.58	GO:0004871	signal transducer activity
0.37	GO:0005515	protein binding
0.34	GO:0042301	phosphate ion binding
0.34	GO:0044877	macromolecular complex binding

0.43	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|O09043|NAPSA_MOUSE
Napsin-A
Search

NAPSA

0.85	Napsin A aspartic peptidase

0.61	GO:0006508	proteolysis
0.55	GO:0043129	surfactant homeostasis
0.45	GO:0006914	autophagy
0.43	GO:0030163	protein catabolic process
0.41	GO:0051604	protein maturation
0.39	GO:0003406	retinal pigment epithelium development
0.38	GO:0061061	muscle structure development
0.37	GO:0009617	response to bacterium
0.36	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0071805	potassium ion transmembrane transport

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.36	GO:0005249	voltage-gated potassium channel activity
0.35	GO:0005515	protein binding

0.66	GO:0005764	lysosome
0.56	GO:0097208	alveolar lamellar body
0.48	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:0005768	endosome
0.36	GO:0008076	voltage-gated potassium channel complex
0.34	GO:0044433	cytoplasmic vesicle part
0.33	GO:0031974	membrane-enclosed lumen

sp|O09044|SNP23_MOUSE
Synaptosomal-associated protein 23
Search

SNAP23

0.77	Synaptosomal-associated protein (Fragment)

0.79	GO:0023061	signal release
0.75	GO:0002349	histamine production involved in inflammatory response
0.75	GO:0006887	exocytosis
0.75	GO:0001821	histamine secretion
0.72	GO:0002279	mast cell activation involved in immune response
0.71	GO:0002448	mast cell mediated immunity
0.69	GO:0051656	establishment of organelle localization
0.69	GO:0032418	lysosome localization
0.69	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.67	GO:0009914	hormone transport

0.80	GO:0019905	syntaxin binding
0.60	GO:0005484	SNAP receptor activity

0.81	GO:0031201	SNARE complex
0.73	GO:0099503	secretory vesicle
0.71	GO:0042629	mast cell granule
0.71	GO:0005766	primary lysosome
0.67	GO:0005913	cell-cell adherens junction
0.67	GO:0098793	presynapse
0.62	GO:0012505	endomembrane system
0.60	GO:0031083	BLOC-1 complex
0.59	GO:0005654	nucleoplasm
0.59	GO:0030424	axon

sp|O09046|OXLA_MOUSE
L-amino-acid oxidase
Search

0.49	L-amino-acid oxidase

0.52	GO:0055114	oxidation-reduction process
0.38	GO:0042742	defense response to bacterium
0.38	GO:0044179	hemolysis in other organism
0.37	GO:0006915	apoptotic process
0.36	GO:0009072	aromatic amino acid family metabolic process
0.36	GO:0009405	pathogenesis
0.34	GO:0045087	innate immune response
0.33	GO:0009063	cellular amino acid catabolic process
0.32	GO:0016109	tetraterpenoid biosynthetic process
0.32	GO:0016116	carotenoid metabolic process

0.54	GO:0016491	oxidoreductase activity
0.37	GO:0090729	toxin activity
0.32	GO:0071949	FAD binding

0.38	GO:0005764	lysosome
0.37	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.54

GO:0016491

sp|O09047|C3AR_MOUSE
C3a anaphylatoxin chemotactic receptor
Search

C3AR1

0.97	Complement component 3A receptor 1

0.80	GO:0002430	complement receptor mediated signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.64	GO:0006935	chemotaxis
0.63	GO:0010759	positive regulation of macrophage chemotaxis
0.62	GO:0090023	positive regulation of neutrophil chemotaxis
0.62	GO:0010575	positive regulation of vascular endothelial growth factor production
0.59	GO:0045766	positive regulation of angiogenesis
0.59	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.48	GO:0006954	inflammatory response
0.47	GO:0050900	leukocyte migration

0.80	GO:0004876	complement component C3a receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.45	GO:0004878	complement component C5a receptor activity
0.39	GO:0001653	peptide receptor activity
0.38	GO:0001850	complement component C3a binding
0.36	GO:0004896	cytokine receptor activity
0.35	GO:0042923	neuropeptide binding
0.34	GO:0003735	structural constituent of ribosome
0.33	GO:0004749	ribose phosphate diphosphokinase activity
0.33	GO:0035757	chemokine (C-C motif) ligand 19 binding

0.43	GO:0005887	integral component of plasma membrane
0.37	GO:0035579	specific granule membrane
0.37	GO:0035577	azurophil granule membrane
0.35	GO:0009925	basal plasma membrane
0.34	GO:0045177	apical part of cell
0.34	GO:0043005	neuron projection
0.33	GO:0005840	ribosome
0.32	GO:0009897	external side of plasma membrane
0.32	GO:0005654	nucleoplasm
0.32	GO:0005739	mitochondrion

0.33	EC:2.7.6.1	GO:0004749
0.33	KEGG:R01049	GO:0004749

tr|O09048|O09048_MOUSE
Glycine tyrosine-rich hair keratin protein
Search

0.93	Truncated keratin associated protein 6

0.79

GO:0005882

intermediate filament

sp|O09049|REG3G_MOUSE
Regenerating islet-derived protein 3-gamma
Search

0.97	Pancreatic beta cell growth factor

0.69	GO:0044278	cell wall disruption in other organism
0.66	GO:0045617	negative regulation of keratinocyte differentiation
0.65	GO:0010838	positive regulation of keratinocyte proliferation
0.64	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.62	GO:0090303	positive regulation of wound healing
0.62	GO:0050830	defense response to Gram-positive bacterium
0.61	GO:0051715	cytolysis in other organism
0.60	GO:0050829	defense response to Gram-negative bacterium
0.59	GO:0006953	acute-phase response
0.53	GO:0002755	MyD88-dependent toll-like receptor signaling pathway

0.64	GO:0070492	oligosaccharide binding
0.60	GO:0005539	glycosaminoglycan binding
0.51	GO:0042802	identical protein binding
0.47	GO:2001065	mannan binding
0.41	GO:1901681	sulfur compound binding
0.40	GO:0019838	growth factor binding
0.37	GO:0008083	growth factor activity
0.36	GO:0043168	anion binding
0.35	GO:0004421	hydroxymethylglutaryl-CoA synthase activity
0.35	GO:0005509	calcium ion binding

0.52	GO:0030141	secretory granule
0.52	GO:0005576	extracellular region
0.43	GO:0044216	other organism cell
0.39	GO:0045177	apical part of cell
0.36	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.35	EC:2.3.3.10	GO:0004421
0.35	KEGG:R01978	GO:0004421

sp|O09051|GUC2B_MOUSE
Guanylate cyclase activator 2B
Search

GUCA2B

0.97	Lymphoguanylin

0.86	GO:0031284	positive regulation of guanylate cyclase activity
0.74	GO:0045776	negative regulation of blood pressure
0.74	GO:0007588	excretion
0.73	GO:0007589	body fluid secretion
0.70	GO:0006182	cGMP biosynthetic process
0.40	GO:0030104	water homeostasis
0.39	GO:0007586	digestion
0.38	GO:0050801	ion homeostasis

0.86	GO:0010853	cyclase activator activity
0.86	GO:0030249	guanylate cyclase regulator activity
0.75	GO:0008047	enzyme activator activity

0.72	GO:0001750	photoreceptor outer segment
0.66	GO:0005576	extracellular region
0.40	GO:0031982	vesicle

sp|O09053|WRN_MOUSE
Werner syndrome ATP-dependent helicase homolog
Search

WRN

0.96	Werner syndrome ATP-dependent helicase

0.70	GO:0032392	DNA geometric change
0.66	GO:0006260	DNA replication
0.65	GO:0006310	DNA recombination
0.65	GO:0006281	DNA repair
0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.63	GO:0098530	positive regulation of strand invasion
0.61	GO:1902570	protein localization to nucleolus
0.61	GO:0061820	telomeric D-loop disassembly
0.59	GO:0010225	response to UV-C
0.59	GO:0040009	regulation of growth rate

0.80	GO:0043140	ATP-dependent 3'-5' DNA helicase activity
0.71	GO:0008408	3'-5' exonuclease activity
0.62	GO:0070337	3'-flap-structured DNA binding
0.62	GO:0061749	forked DNA-dependent helicase activity
0.61	GO:1905773	8-hydroxy-2'-deoxyguanosine DNA binding
0.61	GO:0061821	telomeric D-loop binding
0.59	GO:0000405	bubble DNA binding
0.59	GO:0051880	G-quadruplex DNA binding
0.59	GO:0000403	Y-form DNA binding
0.58	GO:0000400	four-way junction DNA binding

0.59	GO:0032389	MutLalpha complex
0.55	GO:0000781	chromosome, telomeric region
0.55	GO:0016607	nuclear speck
0.54	GO:0005813	centrosome
0.52	GO:0005730	nucleolus
0.51	GO:0005657	replication fork
0.40	GO:0043005	neuron projection
0.37	GO:0005737	cytoplasm
0.34	GO:0030529	intracellular ribonucleoprotein complex

sp|O09061|PSB1_MOUSE
Proteasome subunit beta type-1
Search

PSMB1

0.53	Proteasome subunit beta type

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0043632	modification-dependent macromolecule catabolic process
0.35	GO:0043312	neutrophil degranulation

0.77	GO:0070003	threonine-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding

0.76	GO:0005839	proteasome core complex
0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0097708	intracellular vesicle
0.33	GO:0044446	intracellular organelle part
0.33	GO:0012505	endomembrane system

sp|O09100|GATA2_MOUSE
Endothelial transcription factor GATA-2
Search

GATA2

0.92	GATA binding protein 2

0.78	GO:0030097	hemopoiesis
0.73	GO:2000352	negative regulation of endothelial cell apoptotic process
0.72	GO:0021514	ventral spinal cord interneuron differentiation
0.72	GO:0045599	negative regulation of fat cell differentiation
0.72	GO:0070345	negative regulation of fat cell proliferation
0.70	GO:2000977	regulation of forebrain neuron differentiation
0.70	GO:0010725	regulation of primitive erythrocyte differentiation
0.69	GO:0045650	negative regulation of macrophage differentiation
0.69	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain
0.69	GO:0045654	positive regulation of megakaryocyte differentiation

0.70	GO:0070742	C2H2 zinc finger domain binding
0.69	GO:0001158	enhancer sequence-specific DNA binding
0.67	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.65	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.65	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.64	GO:0000987	proximal promoter sequence-specific DNA binding
0.64	GO:0003682	chromatin binding
0.63	GO:0008270	zinc ion binding
0.63	GO:0008134	transcription factor binding
0.48	GO:0071837	HMG box domain binding

0.60	GO:0005634	nucleus
0.57	GO:0070013	intracellular organelle lumen
0.51	GO:0005667	transcription factor complex
0.50	GO:0044446	intracellular organelle part
0.42	GO:0005694	chromosome

sp|O09101|PIGF_MOUSE
Phosphatidylinositol-glycan biosynthesis class F protein
Search

PIGF

0.97	Phosphatidylinositol glycan anchor biosynthesis class F

0.78	GO:0006506	GPI anchor biosynthetic process
0.32	GO:0006606	protein import into nucleus
0.32	GO:0032259	methylation
0.31	GO:0055085	transmembrane transport

0.38	GO:0004307	ethanolaminephosphotransferase activity
0.32	GO:0061608	nuclear import signal receptor activity
0.32	GO:0008565	protein transporter activity
0.32	GO:0008168	methyltransferase activity
0.32	GO:0003723	RNA binding
0.31	GO:0022857	transmembrane transporter activity

0.72	GO:0005789	endoplasmic reticulum membrane
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.38

EC:2.7.8.1

GO:0004307

sp|O09102|GCM2_MOUSE
Chorion-specific transcription factor GCMb
Search

GCM2

0.97	Chorion-specific transcription factor GCMb

0.70	GO:0007275	multicellular organism development
0.61	GO:0055074	calcium ion homeostasis
0.58	GO:0006351	transcription, DNA-templated
0.58	GO:0072503	cellular divalent inorganic cation homeostasis
0.58	GO:0072502	cellular trivalent inorganic anion homeostasis
0.58	GO:0072501	cellular divalent inorganic anion homeostasis
0.58	GO:0030320	cellular monovalent inorganic anion homeostasis
0.58	GO:0055062	phosphate ion homeostasis
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.55	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.55	GO:0003677	DNA binding
0.38	GO:0042826	histone deacetylase binding
0.37	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0008134	transcription factor binding
0.35	GO:0046872	metal ion binding
0.33	GO:0015035	protein disulfide oxidoreductase activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.31	GO:0032555	purine ribonucleotide binding

0.61	GO:0005634	nucleus
0.37	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|O09105|NDF4_MOUSE
Neurogenic differentiation factor 4
Search

NEUROD4

0.89	Neurogenic differentiation factor

0.77	GO:0048666	neuron development
0.66	GO:0035881	amacrine cell differentiation
0.60	GO:0045597	positive regulation of cell differentiation
0.59	GO:0045165	cell fate commitment
0.55	GO:0007405	neuroblast proliferation
0.55	GO:0006351	transcription, DNA-templated
0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.54	GO:0001764	neuron migration

0.68	GO:0046983	protein dimerization activity
0.52	GO:0003677	DNA binding
0.51	GO:0001105	RNA polymerase II transcription coactivator activity
0.51	GO:0001102	RNA polymerase II activating transcription factor binding
0.49	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.47	GO:0003682	chromatin binding

0.58	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.40	GO:0044446	intracellular organelle part
0.37	GO:0005737	cytoplasm
0.34	GO:0070013	intracellular organelle lumen

sp|O09106|HDAC1_MOUSE
Histone deacetylase 1
Search

HDAC1

0.52	Histone deacetylase

0.80	GO:0016575	histone deacetylation
0.55	GO:0006346	methylation-dependent chromatin silencing
0.55	GO:0010870	positive regulation of receptor biosynthetic process
0.55	GO:0043922	negative regulation by host of viral transcription
0.55	GO:0060766	negative regulation of androgen receptor signaling pathway
0.54	GO:0006351	transcription, DNA-templated
0.52	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.51	GO:0042127	regulation of cell proliferation
0.50	GO:0000122	negative regulation of transcription by RNA polymerase II
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II

0.80	GO:0004407	histone deacetylase activity
0.73	GO:0034979	NAD-dependent protein deacetylase activity
0.54	GO:0051059	NF-kappaB binding
0.54	GO:0001103	RNA polymerase II repressing transcription factor binding
0.53	GO:0001106	RNA polymerase II transcription corepressor activity
0.53	GO:0047485	protein N-terminus binding
0.53	GO:0046872	metal ion binding
0.53	GO:0033613	activating transcription factor binding
0.52	GO:0002039	p53 binding
0.52	GO:0042826	histone deacetylase binding

0.58	GO:0005634	nucleus
0.51	GO:0017053	transcriptional repressor complex
0.48	GO:0000785	chromatin
0.46	GO:0070013	intracellular organelle lumen
0.46	GO:0005829	cytosol
0.45	GO:1904949	ATPase complex
0.43	GO:0043025	neuronal cell body
0.43	GO:0043234	protein complex
0.39	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0043005	neuron projection

0.80

GO:0004407

sp|O09107|INSL3_MOUSE
Insulin-like 3
Search

INSL3

0.90	Insulin like 3

0.75	GO:0010469	regulation of receptor activity
0.54	GO:0090303	positive regulation of wound healing
0.53	GO:0010634	positive regulation of epithelial cell migration
0.53	GO:0008584	male gonad development
0.51	GO:2000018	regulation of male gonad development
0.51	GO:0043950	positive regulation of cAMP-mediated signaling
0.50	GO:0001556	oocyte maturation
0.49	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.48	GO:0001701	in utero embryonic development
0.47	GO:0008285	negative regulation of cell proliferation

0.78	GO:0005179	hormone activity
0.53	GO:0002020	protease binding
0.47	GO:0001664	G-protein coupled receptor binding
0.41	GO:0005158	insulin receptor binding

0.66	GO:0005576	extracellular region
0.47	GO:0048471	perinuclear region of cytoplasm

sp|O09108|LSHB_MOUSE
Lutropin subunit beta
Search

LHB

0.91	LOW QUALITY PROTEIN: lutropin subunit beta

0.76	GO:0010469	regulation of receptor activity
0.58	GO:0030728	ovulation
0.52	GO:0009755	hormone-mediated signaling pathway
0.52	GO:0007267	cell-cell signaling
0.49	GO:0007186	G-protein coupled receptor signaling pathway
0.44	GO:0030823	regulation of cGMP metabolic process
0.40	GO:0006701	progesterone biosynthetic process
0.38	GO:0009914	hormone transport
0.38	GO:0016486	peptide hormone processing
0.38	GO:0008584	male gonad development

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.39	GO:0031982	vesicle
0.39	GO:0005737	cytoplasm
0.36	GO:0012505	endomembrane system
0.36	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0043231	intracellular membrane-bounded organelle

sp|O09110|MP2K3_MOUSE
Dual specificity mitogen-activated protein kinase kinase 3
Search

MAP2K3

0.96	Dual specificity mitogen-activated protein kinase kinase 3

0.62	GO:0006468	protein phosphorylation
0.58	GO:0060048	cardiac muscle contraction
0.58	GO:0000187	activation of MAPK activity
0.56	GO:0031098	stress-activated protein kinase signaling cascade
0.53	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.53	GO:0035924	cellular response to vascular endothelial growth factor stimulus
0.52	GO:0042035	regulation of cytokine biosynthetic process
0.50	GO:0006954	inflammatory response
0.48	GO:0010557	positive regulation of macromolecule biosynthetic process
0.48	GO:0051254	positive regulation of RNA metabolic process

0.67	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0019901	protein kinase binding
0.54	GO:0004708	MAP kinase kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0004713	protein tyrosine kinase activity
0.34	GO:0042802	identical protein binding

0.43	GO:0005829	cytosol
0.41	GO:0005634	nucleus
0.35	GO:0005856	cytoskeleton
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.67

GO:0004674

sp|O09111|NDUBB_MOUSE
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial
Search

NDUFB11

0.91	NADH dehydrogenase 1 beta subcomplex subunit 11, mitochondrial

0.61	GO:0032981	mitochondrial respiratory chain complex I assembly
0.41	GO:0055114	oxidation-reduction process
0.36	GO:0001944	vasculature development
0.36	GO:0007507	heart development
0.36	GO:0006119	oxidative phosphorylation

0.37	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.36	GO:0005515	protein binding

0.59	GO:0005747	mitochondrial respiratory chain complex I
0.30	GO:0016021	integral component of membrane

0.37

EC:1.6.5.3

GO:0008137

sp|O09112|DUS8_MOUSE
Dual specificity protein phosphatase 8
Search

0.93	Dual specificity protein phosphatase 8

0.84	GO:0000188	inactivation of MAPK activity
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.36	GO:0045208	MAPK phosphatase export from nucleus
0.36	GO:0045204	MAPK export from nucleus
0.34	GO:0034397	telomere localization
0.33	GO:0016310	phosphorylation

0.85	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0005515	protein binding
0.33	GO:0016301	kinase activity

0.45	GO:0005654	nucleoplasm
0.37	GO:0005737	cytoplasm
0.34	GO:0097708	intracellular vesicle

0.85

EC:3.1.3

GO:0017017

sp|O09113|OTP_MOUSE
Homeobox protein orthopedia
Search

OTP

0.97	Homeobox protein orthopedia B

0.68	GO:0007275	multicellular organism development
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:2000648	positive regulation of stem cell proliferation
0.55	GO:2000179	positive regulation of neural precursor cell proliferation
0.55	GO:0010468	regulation of gene expression
0.54	GO:0060322	head development
0.52	GO:0010720	positive regulation of cell development
0.52	GO:0051962	positive regulation of nervous system development
0.50	GO:0030154	cell differentiation

0.63

GO:0043565

sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|O09114|PTGDS_MOUSE
Prostaglandin-H2 D-isomerase
Search

PTGDS

0.83	Prostaglandin D synthase

0.72	GO:0046457	prostanoid biosynthetic process
0.71	GO:0006693	prostaglandin metabolic process
0.68	GO:0045187	regulation of circadian sleep/wake cycle, sleep
0.66	GO:2000255	negative regulation of male germ cell proliferation
0.42	GO:0051384	response to glucocorticoid
0.38	GO:0044793	negative regulation by host of viral process
0.38	GO:0019369	arachidonic acid metabolic process
0.38	GO:0045071	negative regulation of viral genome replication
0.36	GO:0006303	double-strand break repair via nonhomologous end joining

0.77	GO:0004667	prostaglandin-D synthase activity
0.66	GO:0005501	retinoid binding
0.51	GO:0036094	small molecule binding
0.36	GO:0005515	protein binding
0.36	GO:0043168	anion binding

0.58	GO:0005791	rough endoplasmic reticulum
0.56	GO:0005576	extracellular region
0.54	GO:0031965	nuclear membrane
0.54	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005794	Golgi apparatus
0.39	GO:0031982	vesicle
0.36	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.77	EC:5.3.99.2	GO:0004667
0.77	KEGG:R02266	GO:0004667

sp|O09116|SPRR3_MOUSE
Small proline-rich protein 3
Search

0.82	Small proline-rich protein 3

0.82	GO:0018149	peptide cross-linking
0.69	GO:0030216	keratinocyte differentiation
0.38	GO:0042060	wound healing
0.38	GO:0012501	programmed cell death

0.52	GO:0005198	structural molecule activity
0.44	GO:0005515	protein binding
0.37	GO:0060090	molecular adaptor activity

0.70	GO:0001533	cornified envelope
0.60	GO:0048471	perinuclear region of cytoplasm
0.56	GO:0005794	Golgi apparatus
0.47	GO:0070062	extracellular exosome
0.37	GO:0005938	cell cortex
0.36	GO:0005829	cytosol

sp|O09117|SYPL1_MOUSE
Synaptophysin-like protein 1
Search

SYPL1

0.61	Synaptophysin like 1

0.40	GO:0048168	regulation of neuronal synaptic plasticity
0.34	GO:0007268	chemical synaptic transmission
0.32	GO:0006508	proteolysis

0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.82	GO:0008021	synaptic vesicle
0.50	GO:0030141	secretory granule
0.48	GO:0099501	exocytic vesicle membrane
0.45	GO:0031301	integral component of organelle membrane
0.38	GO:0070062	extracellular exosome
0.37	GO:0042470	melanosome
0.33	GO:0005887	integral component of plasma membrane

0.33

GO:0004252

sp|O09118|NET1_MOUSE
Netrin-1
Search

0.89	LOW QUALITY PROTEIN: netrin-3

0.56	GO:0030516	regulation of axon extension
0.56	GO:0071678	olfactory bulb axon guidance
0.55	GO:0021960	anterior commissure morphogenesis
0.52	GO:0033564	anterior/posterior axon guidance
0.52	GO:0016358	dendrite development
0.49	GO:0035908	ventral aorta development
0.49	GO:0048562	embryonic organ morphogenesis
0.48	GO:0051093	negative regulation of developmental process
0.48	GO:0051241	negative regulation of multicellular organismal process
0.47	GO:0061626	pharyngeal arch artery morphogenesis

0.38

GO:0005515

protein binding

0.65	GO:0005576	extracellular region
0.35	GO:0005737	cytoplasm
0.35	GO:0012505	endomembrane system
0.33	GO:0043227	membrane-bounded organelle
0.33	GO:0043229	intracellular organelle
0.33	GO:0071944	cell periphery

sp|O09126|SEM4D_MOUSE
Semaphorin-4D
Search

SEMA4D

0.95	Semaphorin-4D isoform A

0.58	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis
0.58	GO:0010693	negative regulation of alkaline phosphatase activity
0.57	GO:0070486	leukocyte aggregation
0.57	GO:0048672	positive regulation of collateral sprouting
0.57	GO:0043931	ossification involved in bone maturation
0.55	GO:0045668	negative regulation of osteoblast differentiation
0.55	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.55	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation
0.55	GO:0048814	regulation of dendrite morphogenesis
0.54	GO:0007162	negative regulation of cell adhesion

0.57	GO:0030215	semaphorin receptor binding
0.50	GO:0038191	neuropilin binding
0.48	GO:0004888	transmembrane signaling receptor activity
0.38	GO:0042802	identical protein binding

0.51	GO:0005615	extracellular space
0.47	GO:0005887	integral component of plasma membrane

sp|O09127|EPHA8_MOUSE
Ephrin type-A receptor 8
Search

EPHA8

0.86	Eph receptor A3, like

0.84	GO:0048013	ephrin receptor signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.72	GO:0071372	cellular response to follicle-stimulating hormone stimulus
0.70	GO:0006929	substrate-dependent cell migration
0.70	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
0.69	GO:0016322	neuron remodeling
0.69	GO:0033628	regulation of cell adhesion mediated by integrin
0.65	GO:0007411	axon guidance
0.64	GO:0046777	protein autophosphorylation
0.63	GO:0043410	positive regulation of MAPK cascade

0.85	GO:0005004	GPI-linked ephrin receptor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.65	GO:0005887	integral component of plasma membrane
0.62	GO:0043005	neuron projection
0.36	GO:0005912	adherens junction

sp|O09130|NF2IP_MOUSE
NFATC2-interacting protein
Search

NFATC2IP

0.97	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein (Fragment)

0.80	GO:0001816	cytokine production
0.71	GO:0045944	positive regulation of transcription by RNA polymerase II
0.59	GO:0016925	protein sumoylation

0.61

GO:0031386

protein tag

0.48

GO:0005634

nucleus

sp|O09131|GSTO1_MOUSE
Glutathione S-transferase omega-1
Search

GSTO1

0.87	Glutathione S-transferase omega-1

0.58	GO:0071243	cellular response to arsenic-containing substance
0.56	GO:0019852	L-ascorbic acid metabolic process
0.53	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity
0.52	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
0.52	GO:0006805	xenobiotic metabolic process
0.52	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.51	GO:0098754	detoxification
0.48	GO:0097237	cellular response to toxic substance
0.48	GO:0090487	secondary metabolite catabolic process
0.48	GO:0006749	glutathione metabolic process

0.79	GO:0004364	glutathione transferase activity
0.59	GO:0045174	glutathione dehydrogenase (ascorbate) activity
0.44	GO:0050610	methylarsonate reductase activity
0.42	GO:0042802	identical protein binding
0.34	GO:0016648	oxidoreductase activity, acting on the CH-NH group of donors, disulfide as acceptor
0.33	GO:0016782	transferase activity, transferring sulfur-containing groups
0.32	GO:0046983	protein dimerization activity
0.32	GO:0003677	DNA binding

0.49	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.35	GO:0043209	myelin sheath
0.35	GO:0005604	basement membrane
0.35	GO:0044297	cell body
0.35	GO:0030424	axon
0.35	GO:0031965	nuclear membrane

0.79	EC:2.5.1.18	GO:0004364
0.59	KEGG:R01108	GO:0045174

sp|O09133|SMR2A_MOUSE
Submaxillary gland androgen-regulated protein 2, isoform alpha
Search

0.92	Submaxillary gland androgen-regulated protein 2, isoform alpha

0.63

GO:0009636

response to toxic substance

0.62

GO:0005576

extracellular region

sp|O09158|CP3AP_MOUSE
Cytochrome P450 3A25
Search

0.76	Lithocholate 6-beta-hydroxylase

0.53	GO:0055114	oxidation-reduction process
0.51	GO:0002933	lipid hydroxylation
0.49	GO:0009822	alkaloid catabolic process
0.48	GO:0008202	steroid metabolic process
0.45	GO:0070988	demethylation
0.42	GO:0016098	monoterpenoid metabolic process
0.42	GO:0042445	hormone metabolic process
0.42	GO:0042738	exogenous drug catabolic process
0.41	GO:0042362	fat-soluble vitamin biosynthetic process
0.40	GO:1901615	organic hydroxy compound metabolic process

0.79	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.52	GO:0008395	steroid hydroxylase activity
0.42	GO:0030343	vitamin D3 25-hydroxylase activity
0.42	GO:0034875	caffeine oxidase activity
0.42	GO:0070576	vitamin D 24-hydroxylase activity
0.40	GO:0005496	steroid binding
0.38	GO:0019899	enzyme binding
0.37	GO:0019825	oxygen binding

0.45	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0031090	organelle membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.79	EC:1.14.14	GO:0016712
0.36	KEGG:R07203	GO:0033777

sp|O09159|MA2B1_MOUSE
Lysosomal alpha-mannosidase
Search

MAN2B1

0.47	Lysosomal alpha-mannosidase

0.81	GO:0006013	mannose metabolic process
0.51	GO:0006517	protein deglycosylation
0.48	GO:0007611	learning or memory
0.36	GO:0043312	neutrophil degranulation
0.35	GO:0009313	oligosaccharide catabolic process

0.79	GO:0004559	alpha-mannosidase activity
0.70	GO:0030246	carbohydrate binding
0.53	GO:0046872	metal ion binding
0.33	GO:0036094	small molecule binding

0.42	GO:0005764	lysosome
0.38	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:0034774	secretory granule lumen
0.36	GO:0005775	vacuolar lumen
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:3.2.1.24

GO:0004559

sp|O09160|FUT1_MOUSE
Galactoside 2-alpha-L-fucosyltransferase 1
Search

FUT1

0.83	L-Fucosyltransferase

0.81	GO:0036065	fucosylation
0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.60	GO:0005975	carbohydrate metabolic process
0.60	GO:0036211	protein modification process
0.55	GO:0044267	cellular protein metabolic process
0.34	GO:0044282	small molecule catabolic process
0.34	GO:1901575	organic substance catabolic process

0.84

GO:0008107

galactoside 2-alpha-L-fucosyltransferase activity

0.81	GO:0032580	Golgi cisterna membrane
0.35	GO:0070062	extracellular exosome
0.33	GO:0005887	integral component of plasma membrane

0.84

EC:2.4.1.69

GO:0008107

sp|O09161|CASQ2_MOUSE
Calsequestrin-2
Search

CASQ2

0.91	Calsequestrin

0.58	GO:0051208	sequestering of calcium ion
0.58	GO:0071313	cellular response to caffeine
0.58	GO:0010649	regulation of cell communication by electrical coupling
0.58	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
0.58	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
0.56	GO:1901017	negative regulation of potassium ion transmembrane transporter activity
0.56	GO:0060306	regulation of membrane repolarization
0.55	GO:0060048	cardiac muscle contraction
0.55	GO:0045214	sarcomere organization
0.55	GO:0002027	regulation of heart rate

0.70	GO:0005509	calcium ion binding
0.55	GO:0048306	calcium-dependent protein binding
0.36	GO:0042802	identical protein binding
0.35	GO:0005080	protein kinase C binding
0.35	GO:0046983	protein dimerization activity
0.32	GO:0016887	ATPase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008144	drug binding

0.60	GO:0033018	sarcoplasmic reticulum lumen
0.56	GO:0030314	junctional membrane complex
0.54	GO:0030018	Z disc
0.42	GO:0014802	terminal cisterna
0.36	GO:0005891	voltage-gated calcium channel complex
0.35	GO:0014701	junctional sarcoplasmic reticulum membrane
0.33	GO:0005759	mitochondrial matrix

0.32

GO:0016887

sp|O09164|SODE_MOUSE
Extracellular superoxide dismutase [Cu-Zn]
Search

SOD3

0.52	Extracellular superoxide dismutase [Cu-Zn]

0.75	GO:0071450	cellular response to oxygen radical
0.75	GO:0000303	response to superoxide
0.75	GO:0006801	superoxide metabolic process
0.69	GO:0098869	cellular oxidant detoxification
0.52	GO:0055114	oxidation-reduction process
0.52	GO:0001666	response to hypoxia
0.39	GO:0046688	response to copper ion
0.38	GO:0007568	aging
0.38	GO:0050665	hydrogen peroxide biosynthetic process
0.38	GO:0060087	relaxation of vascular smooth muscle

0.77	GO:0004784	superoxide dismutase activity
0.54	GO:0046872	metal ion binding
0.38	GO:0030346	protein phosphatase 2B binding
0.36	GO:0048365	Rac GTPase binding
0.36	GO:0051087	chaperone binding
0.36	GO:0042802	identical protein binding
0.35	GO:0008201	heparin binding
0.34	GO:0016530	metallochaperone activity
0.33	GO:0046983	protein dimerization activity
0.33	GO:0008047	enzyme activator activity

0.50	GO:0005615	extracellular space
0.49	GO:0031012	extracellular matrix
0.38	GO:0005796	Golgi lumen
0.38	GO:0031982	vesicle
0.37	GO:0043230	extracellular organelle
0.37	GO:0005829	cytosol
0.37	GO:0005634	nucleus
0.37	GO:1904115	axon cytoplasm
0.37	GO:0032839	dendrite cytoplasm
0.37	GO:0043209	myelin sheath

0.77

EC:1.15.1.1

GO:0004784

sp|O09165|CASQ1_MOUSE
Calsequestrin-1
Search

CASQ1

0.90	Calsequestrin

0.57	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
0.55	GO:1901341	positive regulation of store-operated calcium channel activity
0.54	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.54	GO:2001256	regulation of store-operated calcium entry
0.54	GO:0045214	sarcomere organization
0.51	GO:0007029	endoplasmic reticulum organization
0.51	GO:0051258	protein polymerization
0.48	GO:0009408	response to heat
0.39	GO:0014894	response to denervation involved in regulation of muscle adaptation
0.39	GO:0051208	sequestering of calcium ion

0.70	GO:0005509	calcium ion binding
0.48	GO:0042802	identical protein binding
0.38	GO:0048306	calcium-dependent protein binding
0.35	GO:0005391	sodium:potassium-exchanging ATPase activity
0.34	GO:0030955	potassium ion binding
0.34	GO:0046983	protein dimerization activity
0.33	GO:0000287	magnesium ion binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding

0.57	GO:0033018	sarcoplasmic reticulum lumen
0.49	GO:0005759	mitochondrial matrix
0.45	GO:0031674	I band
0.43	GO:0014802	terminal cisterna
0.41	GO:0033017	sarcoplasmic reticulum membrane
0.39	GO:0030314	junctional membrane complex
0.39	GO:0030315	T-tubule
0.36	GO:0005794	Golgi apparatus
0.35	GO:0005790	smooth endoplasmic reticulum
0.33	GO:0030529	intracellular ribonucleoprotein complex

0.35

EC:3.6.3.9

GO:0005391

sp|O09167|RL21_MOUSE
60S ribosomal protein L21
Search

RPL21

0.70	Ribosomal protein L21

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.36	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.35	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.35	GO:0019083	viral transcription
0.34	GO:0016072	rRNA metabolic process
0.34	GO:0042254	ribosome biogenesis

0.64	GO:0003735	structural constituent of ribosome
0.35	GO:0005515	protein binding
0.34	GO:0003723	RNA binding
0.33	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.41	GO:0044445	cytosolic part
0.38	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

GO:0016787

sp|O09172|GSH0_MOUSE
Glutamate--cysteine ligase regulatory subunit
Search

GCLM

0.89	Gamma-glutamylcysteine synthetase regulatory subunit

0.78	GO:0006750	glutathione biosynthetic process
0.63	GO:0035227	regulation of glutamate-cysteine ligase activity
0.62	GO:0051351	positive regulation of ligase activity
0.59	GO:0051900	regulation of mitochondrial depolarization
0.57	GO:0008637	apoptotic mitochondrial changes
0.57	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.57	GO:1990830	cellular response to leukemia inhibitory factor
0.55	GO:0050880	regulation of blood vessel size
0.51	GO:0006534	cysteine metabolic process
0.51	GO:0006536	glutamate metabolic process

0.85	GO:0035226	glutamate-cysteine ligase catalytic subunit binding
0.56	GO:0016874	ligase activity
0.51	GO:0046982	protein heterodimerization activity
0.44	GO:0030234	enzyme regulator activity
0.34	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.32	GO:0016740	transferase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.62	GO:0017109	glutamate-cysteine ligase complex
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.56

GO:0016874

sp|O09173|HGD_MOUSE
Homogentisate 1,2-dioxygenase
Search

HGD

0.60	LOW QUALITY PROTEIN: homogentisate 1,2-dioxygenase

0.81	GO:1902222	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process
0.78	GO:0006570	tyrosine metabolic process
0.78	GO:0006558	L-phenylalanine metabolic process
0.76	GO:0009074	aromatic amino acid family catabolic process
0.71	GO:0042737	drug catabolic process
0.53	GO:0055114	oxidation-reduction process

0.82	GO:0004411	homogentisate 1,2-dioxygenase activity
0.50	GO:0042802	identical protein binding
0.34	GO:0046872	metal ion binding

0.37	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol

0.82	EC:1.13.11.5	GO:0004411
0.82	KEGG:R02519	GO:0004411

sp|O09174|AMACR_MOUSE
Alpha-methylacyl-CoA racemase
Search

AMACR

0.69	Alpha-methylacyl-CoA racemase

0.55	GO:0008206	bile acid metabolic process
0.38	GO:0006694	steroid biosynthetic process
0.37	GO:1901617	organic hydroxy compound biosynthetic process
0.37	GO:0072330	monocarboxylic acid biosynthetic process
0.36	GO:0006631	fatty acid metabolic process
0.36	GO:0044242	cellular lipid catabolic process
0.34	GO:0072339	cellular lactam biosynthetic process
0.34	GO:0042316	penicillin metabolic process
0.34	GO:0034440	lipid oxidation
0.34	GO:0006720	isoprenoid metabolic process

0.57	GO:0008111	alpha-methylacyl-CoA racemase activity
0.48	GO:0005102	receptor binding
0.34	GO:0045439	isopenicillin-N epimerase activity
0.34	GO:0016740	transferase activity

0.50	GO:0005777	peroxisome
0.43	GO:0005739	mitochondrion
0.41	GO:0005886	plasma membrane
0.35	GO:0031907	microbody lumen
0.30	GO:0016021	integral component of membrane

0.57	EC:5.1.99.4	GO:0008111
0.34	KEGG:R04147	GO:0045439

sp|O09198|MAL_MOUSE
Myelin and lymphocyte protein
Search

MAL

0.96	myelin and lymphocyte protein isoform X1

0.57	GO:0001766	membrane raft polarization
0.54	GO:0045056	transcytosis
0.54	GO:0042552	myelination
0.51	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.45	GO:0008104	protein localization
0.35	GO:0007417	central nervous system development
0.35	GO:0006915	apoptotic process
0.34	GO:0030154	cell differentiation
0.34	GO:0046907	intracellular transport
0.34	GO:0070727	cellular macromolecule localization

0.64	GO:0019911	structural constituent of myelin sheath
0.36	GO:0016505	peptidase activator activity involved in apoptotic process
0.34	GO:0008289	lipid binding
0.34	GO:0005515	protein binding

0.64	GO:0045121	membrane raft
0.48	GO:0005783	endoplasmic reticulum
0.40	GO:0016324	apical plasma membrane
0.36	GO:0019898	extrinsic component of membrane
0.35	GO:0000139	Golgi membrane
0.34	GO:0070062	extracellular exosome
0.33	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016021	integral component of membrane

tr|O19441|O19441_MOUSE
Histocompatibility 2, Q region locus 1
Search

0.35	Class Ib major histocompatibility complex

0.71	GO:0048002	antigen processing and presentation of peptide antigen
0.64	GO:0006955	immune response
0.52	GO:0001916	positive regulation of T cell mediated cytotoxicity
0.48	GO:0019883	antigen processing and presentation of endogenous antigen
0.46	GO:0010977	negative regulation of neuron projection development
0.43	GO:0002655	regulation of tolerance induction to nonself antigen
0.42	GO:0019884	antigen processing and presentation of exogenous antigen
0.42	GO:0048839	inner ear development
0.42	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity
0.42	GO:0002517	T cell tolerance induction

0.56	GO:0042605	peptide antigen binding
0.54	GO:0030881	beta-2-microglobulin binding
0.52	GO:0046977	TAP binding
0.51	GO:0042608	T cell receptor binding
0.38	GO:0046982	protein heterodimerization activity
0.35	GO:0046703	natural killer cell lectin-like receptor binding
0.35	GO:0042288	MHC class I protein binding

0.71	GO:0042612	MHC class I protein complex
0.49	GO:0070971	endoplasmic reticulum exit site
0.49	GO:0005797	Golgi medial cisterna
0.49	GO:0009986	cell surface
0.47	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane
0.47	GO:0030670	phagocytic vesicle membrane
0.37	GO:0045121	membrane raft
0.35	GO:0032398	MHC class Ib protein complex
0.33	GO:0005615	extracellular space

tr|O19442|O19442_MOUSE
Histocompatibility 2, M region locus 9
Search

HLA-A

0.41	Leucocyte antigen A

0.82	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
0.74	GO:0006955	immune response

0.81	GO:0042612	MHC class I protein complex
0.30	GO:0031224	intrinsic component of membrane

tr|O19443|O19443_MOUSE
Histocompatibility 2, M region locus 10.1
Search

0.39	Major histocompatibility complex class I antigen

0.63	GO:0048002	antigen processing and presentation of peptide antigen
0.55	GO:0006955	immune response
0.41	GO:0002475	antigen processing and presentation via MHC class Ib
0.41	GO:0001916	positive regulation of T cell mediated cytotoxicity
0.40	GO:0019883	antigen processing and presentation of endogenous antigen
0.40	GO:0002717	positive regulation of natural killer cell mediated immunity
0.40	GO:0042269	regulation of natural killer cell mediated cytotoxicity
0.40	GO:0032759	positive regulation of TRAIL production
0.39	GO:0046631	alpha-beta T cell activation
0.39	GO:2000566	positive regulation of CD8-positive, alpha-beta T cell proliferation

0.49	GO:0042605	peptide antigen binding
0.44	GO:0005102	receptor binding
0.39	GO:0030881	beta-2-microglobulin binding
0.37	GO:0032403	protein complex binding

0.59	GO:0042612	MHC class I protein complex
0.41	GO:0032398	MHC class Ib protein complex
0.38	GO:0009986	cell surface
0.36	GO:0070062	extracellular exosome
0.35	GO:0098552	side of membrane
0.35	GO:0030670	phagocytic vesicle membrane
0.34	GO:0030176	integral component of endoplasmic reticulum membrane

sp|O35047|HOP2_MOUSE
Homologous-pairing protein 2 homolog
Search

PSMC3IP

0.89	Homologous-pairing protein 2 homolog

0.82	GO:0007131	reciprocal meiotic recombination
0.44	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:1902680	positive regulation of RNA biosynthetic process
0.34	GO:0010628	positive regulation of gene expression
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.59	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.36	GO:0050692	DBD domain binding
0.36	GO:0035259	glucocorticoid receptor binding
0.36	GO:0046966	thyroid hormone receptor binding
0.36	GO:0050681	androgen receptor binding
0.36	GO:0030331	estrogen receptor binding
0.35	GO:0042803	protein homodimerization activity
0.34	GO:0003677	DNA binding

0.51	GO:0005654	nucleoplasm
0.41	GO:1905369	endopeptidase complex
0.38	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|O35054|CLD4_MOUSE
Claudin-4
Search

CLDN4

0.69

Claudin

0.56	GO:0070293	renal absorption
0.55	GO:0061436	establishment of skin barrier
0.55	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.54	GO:0045216	cell-cell junction organization
0.51	GO:1902476	chloride transmembrane transport
0.50	GO:0003382	epithelial cell morphogenesis
0.50	GO:0051291	protein heterooligomerization
0.48	GO:0034329	cell junction assembly
0.48	GO:0001666	response to hypoxia
0.47	GO:0051260	protein homooligomerization

0.62	GO:0005198	structural molecule activity
0.51	GO:0005254	chloride channel activity
0.47	GO:0042802	identical protein binding
0.47	GO:0001618	virus receptor activity
0.35	GO:0004888	transmembrane signaling receptor activity

0.81	GO:0005923	bicellular tight junction
0.66	GO:0016327	apicolateral plasma membrane
0.52	GO:0016328	lateral plasma membrane
0.46	GO:0005887	integral component of plasma membrane
0.41	GO:0045178	basal part of cell
0.40	GO:0045177	apical part of cell
0.40	GO:0016323	basolateral plasma membrane
0.39	GO:0034707	chloride channel complex
0.35	GO:0070062	extracellular exosome
0.35	GO:0097574	lateral part of cell

sp|O35066|KIF3C_MOUSE
Kinesin-like protein KIF3C
Search

sp|O35071|KIF1C_MOUSE
Kinesin-like protein KIF1C
Search

KIF1C

0.93	Kinesin superfamily protein 1C

0.74	GO:0007018	microtubule-based movement
0.54	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.49	GO:0030705	cytoskeleton-dependent intracellular transport
0.38	GO:0007270	neuron-neuron synaptic transmission
0.37	GO:0051654	establishment of mitochondrion localization
0.37	GO:0007274	neuromuscular synaptic transmission
0.37	GO:0048917	posterior lateral line ganglion development
0.37	GO:0048918	posterior lateral line nerve development
0.37	GO:1990535	neuron projection maintenance
0.37	GO:0030225	macrophage differentiation

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0016887	ATPase activity
0.34	GO:0042802	identical protein binding
0.34	GO:0003723	RNA binding
0.33	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity

0.50	GO:0005794	Golgi apparatus
0.49	GO:0015630	microtubule cytoskeleton
0.49	GO:0044430	cytoskeletal part
0.45	GO:0099512	supramolecular fiber
0.41	GO:0043234	protein complex
0.37	GO:1904115	axon cytoplasm
0.36	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0005739	mitochondrion
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.42

GO:0016887

sp|O35074|PTGIS_MOUSE
Prostacyclin synthase
Search

PTGIS

0.96	Prostacyclin synthase

0.82	GO:0046457	prostanoid biosynthetic process
0.81	GO:0006693	prostaglandin metabolic process
0.60	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway
0.59	GO:0045019	negative regulation of nitric oxide biosynthetic process
0.58	GO:1900119	positive regulation of execution phase of apoptosis
0.58	GO:0071354	cellular response to interleukin-6
0.56	GO:0071347	cellular response to interleukin-1
0.56	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.56	GO:0050728	negative regulation of inflammatory response
0.56	GO:0071456	cellular response to hypoxia

0.85	GO:0008116	prostaglandin-I synthase activity
0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.34	GO:0005515	protein binding

0.66	GO:0005789	endoplasmic reticulum membrane
0.56	GO:0005901	caveola
0.47	GO:0005615	extracellular space
0.45	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.85	EC:5.3.99.4	GO:0008116
0.85	KEGG:R02267	GO:0008116

sp|O35075|DSCR3_MOUSE
Down syndrome critical region protein 3 homolog
Search

DSCR3

0.91	Down syndrome critical region protein A

0.60	GO:0007165	signal transduction
0.38	GO:0006886	intracellular protein transport

0.38

GO:0008565

protein transporter activity

0.39	GO:0005768	endosome
0.35	GO:0005634	nucleus

sp|O35082|KLOT_MOUSE
Klotho
Search

0.97	Klotho beta

0.81	GO:0008286	insulin receptor signaling pathway
0.80	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0007568	aging
0.62	GO:0030501	positive regulation of bone mineralization
0.60	GO:0005975	carbohydrate metabolic process
0.59	GO:0043410	positive regulation of MAPK cascade
0.58	GO:0055074	calcium ion homeostasis
0.55	GO:0006112	energy reserve metabolic process
0.44	GO:1901657	glycosyl compound metabolic process
0.38	GO:0008284	positive regulation of cell proliferation

0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.66	GO:0017134	fibroblast growth factor binding
0.63	GO:0005104	fibroblast growth factor receptor binding
0.61	GO:0004871	signal transducer activity
0.37	GO:0005499	vitamin D binding
0.37	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.35	GO:0005179	hormone activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.69	GO:0005615	extracellular space
0.44	GO:0005887	integral component of plasma membrane
0.41	GO:0016324	apical plasma membrane
0.38	GO:1903561	extracellular vesicle
0.32	GO:0005622	intracellular

0.66	EC:3.2.1	GO:0004553
0.37	KEGG:R04545	GO:0046934

sp|O35083|PLCA_MOUSE
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
Search

AGPAT1

0.53	1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

0.67	GO:0008654	phospholipid biosynthetic process
0.55	GO:0046473	phosphatidic acid metabolic process
0.55	GO:0001819	positive regulation of cytokine production
0.53	GO:0045017	glycerolipid biosynthetic process
0.39	GO:0046341	CDP-diacylglycerol metabolic process
0.35	GO:0001961	positive regulation of cytokine-mediated signaling pathway
0.34	GO:0031325	positive regulation of cellular metabolic process
0.33	GO:0007010	cytoskeleton organization

0.79	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity
0.33	GO:0005515	protein binding
0.33	GO:0005200	structural constituent of cytoskeleton

0.51	GO:0005783	endoplasmic reticulum
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.33	GO:0005882	intermediate filament
0.30	GO:0016021	integral component of membrane

0.79

EC:2.3.1.51

GO:0003841

sp|O35084|CP27B_MOUSE
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial
Search

CYP27B1

0.42	25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial

0.67	GO:0036378	calcitriol biosynthetic process from calciol
0.65	GO:0070564	positive regulation of vitamin D receptor signaling pathway
0.64	GO:0042369	vitamin D catabolic process
0.64	GO:0010979	regulation of vitamin D 24-hydroxylase activity
0.64	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity
0.63	GO:0070314	G1 to G0 transition
0.62	GO:0045618	positive regulation of keratinocyte differentiation
0.62	GO:0046697	decidualization
0.61	GO:0033280	response to vitamin D
0.61	GO:0030282	bone mineralization

0.68	GO:0004498	calcidiol 1-monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.37	GO:0008176	tRNA (guanine-N7-)-methyltransferase activity
0.35	GO:0000049	tRNA binding
0.35	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.34	GO:0061899	11-cis-retinal 3,4-desaturase activity
0.34	GO:0061898	all-trans retinoic acid 3,4-desaturase activity
0.34	GO:0061897	all-trans retinal 3,4-desaturase activity
0.34	GO:0061896	all-trans retinol 3,4-desaturase activity

0.47	GO:0005739	mitochondrion
0.37	GO:0031967	organelle envelope
0.37	GO:0031090	organelle membrane
0.35	GO:0098805	whole membrane
0.35	GO:0005634	nucleus
0.34	GO:0019867	outer membrane
0.30	GO:0016021	integral component of membrane

0.68	EC:1.14.13.13	GO:0004498
0.68	KEGG:R03610	GO:0004498

sp|O35085|ARX_MOUSE
Homeobox protein ARX
Search

ARX

0.85	Homeobox protein ARX

0.65	GO:0007275	multicellular organism development
0.56	GO:0044241	lipid digestion
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0072148	epithelial cell fate commitment
0.55	GO:0010468	regulation of gene expression
0.55	GO:0048857	neural nucleus development
0.55	GO:0060322	head development
0.54	GO:0046622	positive regulation of organ growth
0.54	GO:0061351	neural precursor cell proliferation

0.63	GO:0043565	sequence-specific DNA binding
0.56	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding
0.54	GO:0035326	enhancer binding
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003682	chromatin binding
0.48	GO:0003690	double-stranded DNA binding
0.34	GO:0004864	protein phosphatase inhibitor activity
0.33	GO:0003779	actin binding

0.61

GO:0005634

nucleus

sp|O35089|CNIH2_MOUSE
Protein cornichon homolog 2
Search

CNIH2

0.97	Cornichon family AMPA receptor auxiliary protein 2

0.67	GO:0016192	vesicle-mediated transport
0.62	GO:2000311	regulation of AMPA receptor activity
0.43	GO:0035249	synaptic transmission, glutamatergic
0.42	GO:1903743	negative regulation of anterograde synaptic vesicle transport
0.41	GO:1902684	negative regulation of receptor localization to synapse
0.41	GO:0042391	regulation of membrane potential
0.40	GO:2000310	regulation of NMDA receptor activity
0.40	GO:0051668	localization within membrane
0.36	GO:0051650	establishment of vesicle localization
0.36	GO:0016050	vesicle organization

0.39	GO:0016247	channel regulator activity
0.35	GO:0005515	protein binding

0.51	GO:0043197	dendritic spine
0.50	GO:0014069	postsynaptic density
0.43	GO:0032281	AMPA glutamate receptor complex
0.43	GO:0043198	dendritic shaft
0.41	GO:0045211	postsynaptic membrane
0.39	GO:0030054	cell junction
0.37	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.36	GO:0012507	ER to Golgi transport vesicle membrane
0.35	GO:0000139	Golgi membrane

sp|O35098|DPYL4_MOUSE
Dihydropyrimidinase-related protein 4
Search

DPYSL4

0.89	Dihydropyrimidinase like 4

0.80	GO:0097485	neuron projection guidance
0.73	GO:0070997	neuron death
0.66	GO:0030516	regulation of axon extension
0.63	GO:0007409	axonogenesis
0.62	GO:0007420	brain development
0.57	GO:0007010	cytoskeleton organization
0.37	GO:0006897	endocytosis
0.37	GO:0014049	positive regulation of glutamate secretion
0.36	GO:0001975	response to amphetamine
0.36	GO:0042220	response to cocaine

0.65	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
0.62	GO:0008092	cytoskeletal protein binding
0.48	GO:0019900	kinase binding
0.38	GO:0051219	phosphoprotein binding
0.36	GO:0042802	identical protein binding
0.35	GO:0016301	kinase activity

0.48	GO:0005737	cytoplasm
0.48	GO:0043209	myelin sheath
0.48	GO:0043025	neuronal cell body
0.48	GO:0030425	dendrite
0.47	GO:0030424	axon
0.39	GO:0043227	membrane-bounded organelle
0.39	GO:0005886	plasma membrane
0.38	GO:0043229	intracellular organelle
0.37	GO:0099512	supramolecular fiber
0.36	GO:0043679	axon terminus

0.65

EC:3.5

GO:0016810

sp|O35099|M3K5_MOUSE
Mitogen-activated protein kinase kinase kinase 5
Search

MAP3K5

0.97	Mitogen-activated protein kinase kinase kinase 5

0.63	GO:0006468	protein phosphorylation
0.58	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress
0.57	GO:0000186	activation of MAPKK activity
0.57	GO:1902170	cellular response to reactive nitrogen species
0.57	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.57	GO:0045663	positive regulation of myoblast differentiation
0.56	GO:0097300	programmed necrotic cell death
0.56	GO:1901216	positive regulation of neuron death
0.56	GO:0043507	positive regulation of JUN kinase activity
0.56	GO:0034198	cellular response to amino acid starvation

0.64	GO:0004672	protein kinase activity
0.55	GO:0005057	signal transducer activity, downstream of receptor
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0019903	protein phosphatase binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0019901	protein kinase binding
0.51	GO:0019904	protein domain specific binding
0.51	GO:0042803	protein homodimerization activity
0.46	GO:0000287	magnesium ion binding

0.58	GO:1990604	IRE1-TRAF2-ASK1 complex
0.53	GO:1902911	protein kinase complex
0.39	GO:0009897	external side of plasma membrane
0.37	GO:0005829	cytosol
0.33	GO:0015630	microtubule cytoskeleton
0.30	GO:0016021	integral component of membrane

sp|O35103|OMD_MOUSE
Osteomodulin
Search

OMD

0.97	Osteomodulin

0.85	GO:0030500	regulation of bone mineralization
0.54	GO:0007409	axonogenesis
0.43	GO:0007155	cell adhesion
0.40	GO:0042340	keratan sulfate catabolic process
0.39	GO:0018146	keratan sulfate biosynthetic process

0.74	GO:0031012	extracellular matrix
0.51	GO:0005615	extracellular space
0.41	GO:1903561	extracellular vesicle
0.39	GO:0043202	lysosomal lumen
0.39	GO:0005796	Golgi lumen

sp|O35111|KCNK3_MOUSE
Potassium channel subfamily K member 3
Search

KCNK3

0.93	Potassium two pore domain channel subfamily K member 3

0.72	GO:0071805	potassium ion transmembrane transport
0.65	GO:0010469	regulation of receptor activity
0.54	GO:0030322	stabilization of membrane potential
0.47	GO:0060047	heart contraction
0.41	GO:0051481	negative regulation of cytosolic calcium ion concentration
0.41	GO:0071294	cellular response to zinc ion
0.40	GO:0090102	cochlea development
0.40	GO:0071456	cellular response to hypoxia
0.39	GO:0007420	brain development
0.37	GO:0042493	response to drug

0.78	GO:0005252	open rectifier potassium channel activity
0.67	GO:0008083	growth factor activity
0.59	GO:0022841	potassium ion leak channel activity
0.53	GO:0044548	S100 protein binding
0.40	GO:0042803	protein homodimerization activity
0.40	GO:0046982	protein heterodimerization activity
0.39	GO:0008022	protein C-terminus binding

0.63	GO:0005615	extracellular space
0.45	GO:0005887	integral component of plasma membrane
0.38	GO:0008021	synaptic vesicle

sp|O35114|SCRB2_MOUSE
Lysosome membrane protein 2
Search

SCARB2

0.88	Scavenger receptor class B member 2

0.73	GO:1905123	regulation of glucosylceramidase activity
0.71	GO:0006622	protein targeting to lysosome
0.66	GO:0001508	action potential
0.42	GO:0030903	notochord development
0.38	GO:0010976	positive regulation of neuron projection development

0.65	GO:0004872	receptor activity
0.58	GO:0019899	enzyme binding

0.79	GO:0005764	lysosome
0.68	GO:0005775	vacuolar lumen
0.62	GO:0098852	lytic vacuole membrane
0.30	GO:0031224	intrinsic component of membrane

sp|O35118|GFRA3_MOUSE
GDNF family receptor alpha-3
Search

GFRA3

0.88	GDNF family receptor alpha-3 variant

0.68	GO:0048485	sympathetic nervous system development
0.65	GO:0001764	neuron migration
0.63	GO:0007411	axon guidance
0.44	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.43	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.38	GO:0000165	MAPK cascade
0.37	GO:0007422	peripheral nervous system development
0.36	GO:0031953	negative regulation of protein autophosphorylation
0.36	GO:0065009	regulation of molecular function

0.70	GO:0008046	axon guidance receptor activity
0.39	GO:0015026	coreceptor activity
0.38	GO:0016167	glial cell-derived neurotrophic factor receptor activity
0.37	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.36	GO:0005102	receptor binding

0.63	GO:0009897	external side of plasma membrane
0.55	GO:0005829	cytosol
0.53	GO:0031225	anchored component of membrane
0.37	GO:0019898	extrinsic component of membrane
0.30	GO:0016021	integral component of membrane

sp|O35125|LRC23_MOUSE
Leucine-rich repeat-containing protein 23
Search

LRRC23

0.97	Leucine-rich repeat-containing protein 23

0.45	GO:0006757	ATP generation from ADP
0.44	GO:0006090	pyruvate metabolic process
0.44	GO:0016052	carbohydrate catabolic process
0.44	GO:0046496	nicotinamide nucleotide metabolic process

0.47	GO:0004634	phosphopyruvate hydratase activity
0.45	GO:0004807	triose-phosphate isomerase activity
0.43	GO:0000287	magnesium ion binding

0.54	GO:0005829	cytosol
0.41	GO:1902494	catalytic complex
0.30	GO:0016020	membrane

0.47	EC:4.2.1.11	GO:0004634
0.45	KEGG:R01015	GO:0004807

sp|O35126|ATN1_MOUSE
Atrophin-1
Search

ATN1

0.82	Arginine-glutamic acid dipeptide repeats

0.69	GO:0051402	neuron apoptotic process
0.66	GO:0000122	negative regulation of transcription by RNA polymerase II
0.51	GO:0021691	cerebellar Purkinje cell layer maturation
0.50	GO:0021942	radial glia guided migration of Purkinje cell
0.50	GO:0021930	cerebellar granule cell precursor proliferation
0.50	GO:0048755	branching morphogenesis of a nerve
0.48	GO:0006366	transcription by RNA polymerase II
0.48	GO:0048813	dendrite morphogenesis
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II
0.46	GO:0006338	chromatin remodeling

0.69	GO:0003714	transcription corepressor activity
0.62	GO:0019904	protein domain specific binding
0.54	GO:0003682	chromatin binding
0.53	GO:0043565	sequence-specific DNA binding
0.52	GO:0001105	RNA polymerase II transcription coactivator activity
0.52	GO:0008270	zinc ion binding
0.51	GO:0003700	DNA binding transcription factor activity
0.48	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.41	GO:0090729	toxin activity
0.40	GO:0008432	JUN kinase binding

0.67	GO:0016363	nuclear matrix
0.59	GO:0005654	nucleoplasm
0.45	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0030054	cell junction
0.40	GO:1902494	catalytic complex
0.38	GO:0031252	cell leading edge

sp|O35127|C10_MOUSE
Protein C10
Search

0.97	Gene-rich cluster, C10 gene

0.85	GO:0036343	psychomotor behavior
0.85	GO:0021678	third ventricle development
0.85	GO:0021540	corpus callosum morphogenesis
0.85	GO:0014819	regulation of skeletal muscle contraction
0.79	GO:0048593	camera-type eye morphogenesis
0.77	GO:0050890	cognition
0.74	GO:0009791	post-embryonic development

0.76	GO:0016607	nuclear speck
0.48	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|O35129|PHB2_MOUSE
Prohibitin-2
Search

PHB2

0.85	Prohibitin 2

0.56	GO:0033600	negative regulation of mammary gland epithelial cell proliferation
0.56	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis
0.55	GO:0031536	positive regulation of exit from mitosis
0.55	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway
0.54	GO:0000060	protein import into nucleus, translocation
0.54	GO:1902808	positive regulation of cell cycle G1/S phase transition
0.53	GO:0060744	mammary gland branching involved in thelarche
0.53	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.53	GO:0043433	negative regulation of DNA binding transcription factor activity
0.52	GO:0051091	positive regulation of DNA binding transcription factor activity

0.53	GO:0047485	protein N-terminus binding
0.52	GO:0008022	protein C-terminus binding
0.47	GO:0033218	amide binding
0.35	GO:0030331	estrogen receptor binding

0.54	GO:0016363	nuclear matrix
0.50	GO:0005741	mitochondrial outer membrane
0.49	GO:0009986	cell surface
0.44	GO:0005743	mitochondrial inner membrane
0.43	GO:0043234	protein complex
0.41	GO:0071944	cell periphery
0.38	GO:0030424	axon
0.36	GO:0070062	extracellular exosome
0.35	GO:0070382	exocytic vesicle

sp|O35130|NEP1_MOUSE
Ribosomal RNA small subunit methyltransferase NEP1
Search

EMG1

0.73	Ribosomal rRNA small subunit methyltransferase NEP1

0.63	GO:0032259	methylation
0.60	GO:0017126	nucleologenesis
0.54	GO:0001824	blastocyst development
0.47	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.44	GO:0000154	rRNA modification
0.37	GO:0044260	cellular macromolecule metabolic process
0.33	GO:0006508	proteolysis

0.63	GO:0008168	methyltransferase activity
0.44	GO:0140102	catalytic activity, acting on a rRNA
0.42	GO:0019843	rRNA binding
0.34	GO:0004252	serine-type endopeptidase activity
0.33	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding

0.47	GO:0032040	small-subunit processome
0.45	GO:0005730	nucleolus
0.34	GO:0005654	nucleoplasm
0.32	GO:0005737	cytoplasm

0.63

GO:0008168

sp|O35134|RPA1_MOUSE
DNA-directed RNA polymerase I subunit RPA1
Search

POLR1A

0.49	DNA-directed RNA polymerase subunit

0.65	GO:1904750	negative regulation of protein localization to nucleolus
0.59	GO:0006360	transcription by RNA polymerase I
0.44	GO:0048703	embryonic viscerocranium morphogenesis
0.43	GO:0014032	neural crest cell development
0.37	GO:0040029	regulation of gene expression, epigenetic
0.36	GO:0009303	rRNA transcription
0.35	GO:0016458	gene silencing
0.35	GO:0006354	DNA-templated transcription, elongation
0.35	GO:0006325	chromatin organization
0.34	GO:0045892	negative regulation of transcription, DNA-templated

0.69	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.62	GO:0008270	zinc ion binding
0.55	GO:0003682	chromatin binding
0.54	GO:0003677	DNA binding
0.35	GO:0005515	protein binding
0.33	GO:0008373	sialyltransferase activity

0.60	GO:0005634	nucleus
0.54	GO:0000428	DNA-directed RNA polymerase complex
0.50	GO:0031974	membrane-enclosed lumen
0.46	GO:0043232	intracellular non-membrane-bounded organelle
0.45	GO:0044446	intracellular organelle part

0.69

GO:0003899

sp|O35136|NCAM2_MOUSE
Neural cell adhesion molecule 2
Search

NCAM2

0.96	Neural cell adhesion molecule 2

0.71	GO:0007155	cell adhesion
0.44	GO:0007413	axonal fasciculation
0.41	GO:0007608	sensory perception of smell
0.34	GO:0001666	response to hypoxia

0.52

GO:0042802

identical protein binding

0.54	GO:0016604	nuclear body
0.53	GO:0030424	axon
0.43	GO:0005886	plasma membrane
0.35	GO:0031225	anchored component of membrane
0.30	GO:0016021	integral component of membrane

sp|O35137|ALX4_MOUSE
Homeobox protein aristaless-like 4
Search

ALX4

0.97	LOW QUALITY PROTEIN: homeobox protein aristaless-like 4

0.69	GO:0007275	multicellular organism development
0.66	GO:0006357	regulation of transcription by RNA polymerase II
0.59	GO:0060021	palate development
0.57	GO:0022405	hair cycle process
0.57	GO:0009653	anatomical structure morphogenesis
0.56	GO:0061061	muscle structure development
0.56	GO:0042981	regulation of apoptotic process
0.55	GO:0008544	epidermis development
0.54	GO:0006366	transcription by RNA polymerase II
0.52	GO:0045893	positive regulation of transcription, DNA-templated

0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0071837	HMG box domain binding
0.58	GO:0003700	DNA binding transcription factor activity
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0046982	protein heterodimerization activity
0.52	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.53	GO:0005667	transcription factor complex

sp|O35143|ATIF1_MOUSE
ATPase inhibitor, mitochondrial
Search

ATPIF1

0.96	Mitochondrial ATPase inhibitory factor 1

0.80	GO:0032780	negative regulation of ATPase activity
0.55	GO:0051882	mitochondrial depolarization
0.53	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
0.53	GO:1904925	positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization
0.52	GO:0030218	erythrocyte differentiation
0.52	GO:0001937	negative regulation of endothelial cell proliferation
0.51	GO:1903578	regulation of ATP metabolic process
0.51	GO:1903214	regulation of protein targeting to mitochondrion
0.49	GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process
0.48	GO:0006783	heme biosynthetic process

0.81	GO:0042030	ATPase inhibitor activity
0.55	GO:0043532	angiostatin binding
0.54	GO:0051117	ATPase binding
0.45	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity
0.40	GO:0005516	calmodulin binding
0.40	GO:0042803	protein homodimerization activity

0.60	GO:0005739	mitochondrion
0.48	GO:0009986	cell surface
0.45	GO:0045259	proton-transporting ATP synthase complex
0.42	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.45	EC:6.3.3.2	GO:0030272
0.45	KEGG:R02301	GO:0030272

sp|O35144|TERF2_MOUSE
Telomeric repeat-binding factor 2
Search

TERF2

0.80	Telomeric repeat-binding factor 2

0.85	GO:0031848	protection from non-homologous end joining at telomere
0.69	GO:1905839	negative regulation of telomeric D-loop disassembly
0.69	GO:1905778	negative regulation of exonuclease activity
0.69	GO:1903770	negative regulation of beta-galactosidase activity
0.68	GO:0032208	negative regulation of telomere maintenance via recombination
0.68	GO:0061820	telomeric D-loop disassembly
0.67	GO:1904430	negative regulation of t-circle formation
0.67	GO:0031627	telomeric loop formation
0.66	GO:1904354	negative regulation of telomere capping
0.65	GO:0032211	negative regulation of telomere maintenance via telomerase

0.82	GO:0042162	telomeric DNA binding
0.75	GO:0042803	protein homodimerization activity
0.64	GO:0003720	telomerase activity
0.63	GO:0098847	sequence-specific single stranded DNA binding
0.61	GO:0008022	protein C-terminus binding
0.56	GO:0003690	double-stranded DNA binding
0.54	GO:0044877	macromolecular complex binding
0.54	GO:0019899	enzyme binding
0.41	GO:0071532	ankyrin repeat binding
0.39	GO:0008301	DNA binding, bending

0.81	GO:0000784	nuclear chromosome, telomeric region
0.64	GO:0000782	telomere cap complex
0.62	GO:0030870	Mre11 complex
0.59	GO:0016604	nuclear body
0.44	GO:0001673	male germ cell nucleus
0.43	GO:1904115	axon cytoplasm
0.39	GO:0001650	fibrillar center
0.34	GO:0005819	spindle

0.64

EC:2.7.7

GO:0003720

sp|O35149|ZNT4_MOUSE
Zinc transporter 4
Search

SLC30A4

0.97	Zinc transporter 4

0.62	GO:0055069	zinc ion homeostasis
0.62	GO:0061088	regulation of sequestering of zinc ion
0.61	GO:0098655	cation transmembrane transport
0.53	GO:0006829	zinc II ion transport
0.50	GO:0010043	response to zinc ion
0.49	GO:0009636	response to toxic substance
0.46	GO:0072503	cellular divalent inorganic cation homeostasis
0.45	GO:0098660	inorganic ion transmembrane transport
0.44	GO:0046916	cellular transition metal ion homeostasis
0.39	GO:0051238	sequestering of metal ion

0.61	GO:0008324	cation transmembrane transporter activity
0.44	GO:0015318	inorganic molecular entity transmembrane transporter activity
0.36	GO:0042803	protein homodimerization activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.56	GO:0005770	late endosome
0.39	GO:0005765	lysosomal membrane
0.38	GO:0010008	endosome membrane
0.38	GO:0030141	secretory granule
0.34	GO:0005886	plasma membrane
0.33	GO:0030658	transport vesicle membrane
0.32	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

sp|O35153|BET1L_MOUSE
BET1-like protein
Search

BET1L

0.81	Bet1 golgi vesicular membrane trafficking protein like

0.59	GO:2000156	regulation of retrograde vesicle-mediated transport, Golgi to ER
0.53	GO:0042147	retrograde transport, endosome to Golgi
0.48	GO:0061025	membrane fusion
0.39	GO:0015031	protein transport
0.35	GO:0006888	ER to Golgi vesicle-mediated transport

0.53

GO:0005484

SNAP receptor activity

0.51	GO:0005768	endosome
0.50	GO:0005794	Golgi apparatus
0.48	GO:0005829	cytosol
0.40	GO:0098588	bounding membrane of organelle
0.39	GO:0031984	organelle subcompartment
0.36	GO:0031201	SNARE complex
0.35	GO:0031301	integral component of organelle membrane

sp|O35160|PITX3_MOUSE
Pituitary homeobox 3
Search

PITX3

0.93	Pituitary homeobox 3

0.69	GO:0007275	multicellular organism development
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0060322	head development
0.54	GO:0007626	locomotory behavior
0.53	GO:0060429	epithelium development
0.53	GO:0006366	transcription by RNA polymerase II
0.52	GO:0048468	cell development
0.52	GO:0051254	positive regulation of RNA metabolic process

0.63	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.53	GO:0044212	transcription regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding
0.41	GO:0001105	RNA polymerase II transcription coactivator activity
0.41	GO:0001102	RNA polymerase II activating transcription factor binding
0.40	GO:0031490	chromatin DNA binding

0.61	GO:0005634	nucleus
0.39	GO:0005667	transcription factor complex
0.39	GO:0043025	neuronal cell body
0.34	GO:0005737	cytoplasm

sp|O35161|CELR1_MOUSE
Cadherin EGF LAG seven-pass G-type receptor 1
Search

CELSR1

0.88	Cadherin EGF LAG seven-pass G-type receptor 1

0.77	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.70	GO:0007166	cell surface receptor signaling pathway
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.53	GO:0048598	embryonic morphogenesis
0.53	GO:0016477	cell migration
0.52	GO:0060489	planar dichotomous subdivision of terminal units involved in lung branching morphogenesis
0.52	GO:0060488	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis
0.52	GO:0060490	lateral sprouting involved in lung morphogenesis
0.50	GO:0090251	protein localization involved in establishment of planar polarity
0.50	GO:0042249	establishment of planar polarity of embryonic epithelium

0.71	GO:0004930	G-protein coupled receptor activity
0.70	GO:0005509	calcium ion binding
0.30	GO:0005515	protein binding

0.55	GO:0005886	plasma membrane
0.43	GO:0005654	nucleoplasm
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|O35164|MCPT9_MOUSE
Mast cell protease 9
Search

0.97	Skeletal muscle neutral protease mekratin

0.61	GO:0006508	proteolysis
0.52	GO:0001909	leukocyte mediated cytotoxicity
0.52	GO:0042222	interleukin-1 biosynthetic process
0.50	GO:0034769	basement membrane disassembly
0.50	GO:0002443	leukocyte mediated immunity
0.50	GO:0032611	interleukin-1 beta production
0.49	GO:0008626	granzyme-mediated apoptotic signaling pathway
0.46	GO:0006955	immune response
0.46	GO:0006952	defense response
0.43	GO:0051851	modification by host of symbiont morphology or physiology

0.69	GO:0004252	serine-type endopeptidase activity
0.41	GO:0008201	heparin binding
0.38	GO:0042277	peptide binding
0.37	GO:0042803	protein homodimerization activity
0.34	GO:0001106	RNA polymerase II transcription corepressor activity
0.33	GO:0002020	protease binding
0.33	GO:0019955	cytokine binding

0.58	GO:0030141	secretory granule
0.47	GO:0044421	extracellular region part
0.40	GO:0010494	cytoplasmic stress granule
0.39	GO:0042629	mast cell granule
0.35	GO:0005634	nucleus
0.35	GO:0005886	plasma membrane
0.35	GO:0044194	cytolytic granule
0.34	GO:0005766	primary lysosome
0.34	GO:0060205	cytoplasmic vesicle lumen
0.34	GO:0009986	cell surface

0.69

GO:0004252

sp|O35166|GOSR2_MOUSE
Golgi SNAP receptor complex member 2
Search

GOSR2

0.92	Golgi SNAP receptor complex member 2

0.68	GO:0016192	vesicle-mediated transport
0.67	GO:0061025	membrane fusion
0.54	GO:0015031	protein transport
0.42	GO:0072666	establishment of protein localization to vacuole
0.42	GO:0048284	organelle fusion
0.42	GO:0016482	cytosolic transport
0.42	GO:0016050	vesicle organization
0.41	GO:0007034	vacuolar transport
0.41	GO:0016197	endosomal transport
0.36	GO:0036498	IRE1-mediated unfolded protein response

0.80	GO:0005484	SNAP receptor activity
0.42	GO:0000149	SNARE binding

0.70	GO:0005794	Golgi apparatus
0.43	GO:0031902	late endosome membrane
0.43	GO:0031201	SNARE complex
0.42	GO:0012507	ER to Golgi transport vesicle membrane
0.42	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0005829	cytosol
0.36	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.30	GO:0016021	integral component of membrane

sp|O35173|KCNS1_MOUSE
Potassium voltage-gated channel subfamily S member 1
Search

KCNS1

0.96	Potassium voltage-gated channel modifier subfamily S member 1

0.77	GO:0051260	protein homooligomerization
0.76	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.63	GO:0043266	regulation of potassium ion transport
0.62	GO:0022898	regulation of transmembrane transporter activity
0.44	GO:0050794	regulation of cellular process
0.37	GO:0052547	regulation of peptidase activity
0.37	GO:0051346	negative regulation of hydrolase activity
0.37	GO:0051248	negative regulation of protein metabolic process

0.78	GO:0005249	voltage-gated potassium channel activity
0.58	GO:0015459	potassium channel regulator activity
0.37	GO:0030414	peptidase inhibitor activity
0.34	GO:0005515	protein binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.60	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005576	extracellular region

sp|O35174|KCNS2_MOUSE
Potassium voltage-gated channel subfamily S member 2
Search

KCNS2

0.97	Potassium voltage-gated channel modifier subfamily S member 2

0.78	GO:0051260	protein homooligomerization
0.77	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.56	GO:0043266	regulation of potassium ion transport
0.55	GO:0022898	regulation of transmembrane transporter activity
0.41	GO:0050794	regulation of cellular process
0.33	GO:0002791	regulation of peptide secretion
0.33	GO:0051223	regulation of protein transport
0.33	GO:0010817	regulation of hormone levels
0.33	GO:0023051	regulation of signaling

0.78	GO:0005249	voltage-gated potassium channel activity
0.42	GO:0015459	potassium channel regulator activity
0.33	GO:0005515	protein binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.53	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0005794	Golgi apparatus
0.41	GO:0005829	cytosol

tr|O35176|O35176_MOUSE
ABPA2
Search

0.97	Androgen binding protein, alpha

0.80

GO:0005496

steroid binding

0.65

GO:0005576

extracellular region

sp|O35177|CASL_MOUSE
Enhancer of filamentation 1
Search

NEDD9

0.94	Enhancer of filamentation 1

0.77	GO:0036032	neural crest cell delamination
0.72	GO:0048041	focal adhesion assembly
0.71	GO:0006929	substrate-dependent cell migration
0.69	GO:0007015	actin filament organization
0.65	GO:0030335	positive regulation of cell migration
0.63	GO:0031532	actin cytoskeleton reorganization
0.59	GO:0040008	regulation of growth
0.56	GO:0007229	integrin-mediated signaling pathway
0.52	GO:0051301	cell division
0.52	GO:0007049	cell cycle

0.50

GO:0005515

protein binding

0.63	GO:0000922	spindle pole
0.58	GO:0005938	cell cortex
0.58	GO:0030027	lamellipodium
0.57	GO:0005925	focal adhesion
0.56	GO:0005654	nucleoplasm
0.55	GO:0005829	cytosol
0.52	GO:0005794	Golgi apparatus
0.47	GO:0005886	plasma membrane

sp|O35181|NRG3_MOUSE
Pro-neuregulin-3, membrane-bound isoform
Search

NRG3

0.92	Pro-neuregulin-3, membrane-bound isoform isoform B

0.53	GO:0021842	chemorepulsion involved in interneuron migration from the subpallium to the cortex
0.51	GO:2001223	negative regulation of neuron migration
0.49	GO:0060596	mammary placode formation
0.47	GO:0007389	pattern specification process
0.44	GO:0035556	intracellular signal transduction
0.38	GO:0010469	regulation of receptor activity
0.38	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity
0.36	GO:0001558	regulation of cell growth

0.51	GO:0045499	chemorepellent activity
0.39	GO:0008083	growth factor activity
0.38	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.37	GO:0030971	receptor tyrosine kinase binding

0.44	GO:0005615	extracellular space
0.36	GO:0005622	intracellular
0.35	GO:0005887	integral component of plasma membrane

sp|O35182|SMAD6_MOUSE
Mothers against decapentaplegic homolog 6
Search

SMAD6

0.65	Mothers against decapentaplegic homolog

0.76	GO:0007179	transforming growth factor beta receptor signaling pathway
0.60	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation
0.59	GO:0007352	zygotic specification of dorsal/ventral axis
0.59	GO:0010991	negative regulation of SMAD protein complex assembly
0.59	GO:0030514	negative regulation of BMP signaling pathway
0.58	GO:0034616	response to laminar fluid shear stress
0.58	GO:0003183	mitral valve morphogenesis
0.58	GO:0003184	pulmonary valve morphogenesis
0.57	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II
0.57	GO:0003148	outflow tract septum morphogenesis

0.60	GO:0070698	type I activin receptor binding
0.60	GO:0030617	transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
0.58	GO:0070410	co-SMAD binding
0.58	GO:0070411	I-SMAD binding
0.58	GO:0034713	type I transforming growth factor beta receptor binding
0.57	GO:0070412	R-SMAD binding
0.57	GO:0003700	DNA binding transcription factor activity
0.53	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0003682	chromatin binding

0.69	GO:0005667	transcription factor complex
0.57	GO:0005634	nucleus
0.49	GO:0005794	Golgi apparatus
0.48	GO:0005829	cytosol
0.47	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.36	GO:0005768	endosome
0.34	GO:0005694	chromosome

sp|O35185|BHE40_MOUSE
Class E basic helix-loop-helix protein 40
Search

BHLHE40

0.97	Class E basic helix-loop-helix protein 40

0.62	GO:0032922	circadian regulation of gene expression
0.60	GO:0043153	entrainment of circadian clock by photoperiod
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0043433	negative regulation of DNA binding transcription factor activity
0.56	GO:0000122	negative regulation of transcription by RNA polymerase II
0.43	GO:0010944	negative regulation of transcription by competitive promoter binding
0.43	GO:0010832	negative regulation of myotube differentiation
0.39	GO:0045475	locomotor rhythm
0.36	GO:0048168	regulation of neuronal synaptic plasticity
0.35	GO:0048731	system development

0.67	GO:0046983	protein dimerization activity
0.64	GO:0043426	MRF binding
0.63	GO:0070888	E-box binding
0.61	GO:0001102	RNA polymerase II activating transcription factor binding
0.60	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.60	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.60	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.59	GO:0003714	transcription corepressor activity
0.54	GO:0042802	identical protein binding
0.53	GO:0019904	protein domain specific binding

0.61	GO:0005634	nucleus
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.35	GO:0005737	cytoplasm
0.33	GO:0017053	transcriptional repressor complex

sp|O35188|X3CL1_MOUSE
Fractalkine
Search

CX3CL1

0.88	Fractalkine

0.88	GO:0050902	leukocyte adhesive activation
0.82	GO:0060326	cell chemotaxis
0.80	GO:0019221	cytokine-mediated signaling pathway
0.74	GO:0006955	immune response
0.73	GO:0051041	positive regulation of calcium-independent cell-cell adhesion
0.68	GO:0032914	positive regulation of transforming growth factor beta1 production
0.67	GO:0033622	integrin activation
0.67	GO:0002523	leukocyte migration involved in inflammatory response
0.66	GO:1905517	macrophage migration
0.65	GO:0060055	angiogenesis involved in wound healing

0.84	GO:0008009	chemokine activity
0.70	GO:0031737	CX3C chemokine receptor binding
0.63	GO:0005178	integrin binding
0.59	GO:0048020	CCR chemokine receptor binding

0.66	GO:0005576	extracellular region
0.60	GO:0009986	cell surface
0.45	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0098794	postsynapse
0.43	GO:0005886	plasma membrane
0.41	GO:0042995	cell projection
0.30	GO:0016021	integral component of membrane

tr|O35192|O35192_MOUSE
Putative pheromone receptor
Search

0.85	Vomeronasal type-2 receptor 26

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:0045925	positive regulation of female receptivity
0.34	GO:0019236	response to pheromone

0.72

GO:0004930

G-protein coupled receptor activity

0.54	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|O35199|O35199_MOUSE
Putative pheromone receptor
Search

0.71	Vomeronasal 2 receptor, 6

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:0045925	positive regulation of female receptivity
0.34	GO:0019236	response to pheromone

0.72

GO:0004930

G-protein coupled receptor activity

0.52	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|O35205|GRAK_MOUSE
Granzyme K
Search

GZMK

0.83	Complement factor D

0.61	GO:0006508	proteolysis
0.39	GO:0006957	complement activation, alternative pathway
0.37	GO:0009405	pathogenesis
0.37	GO:0065008	regulation of biological quality
0.36	GO:0006898	receptor-mediated endocytosis
0.35	GO:0032501	multicellular organismal process
0.35	GO:0051604	protein maturation
0.35	GO:0022900	electron transport chain
0.34	GO:0050819	negative regulation of coagulation
0.34	GO:0061045	negative regulation of wound healing

0.69	GO:0004252	serine-type endopeptidase activity
0.38	GO:0090729	toxin activity
0.37	GO:0005044	scavenger receptor activity
0.36	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.36	GO:0015035	protein disulfide oxidoreductase activity
0.35	GO:0009055	electron transfer activity
0.33	GO:0008061	chitin binding
0.33	GO:0008201	heparin binding
0.33	GO:0042803	protein homodimerization activity
0.33	GO:0005057	signal transducer activity, downstream of receptor

0.41	GO:0005576	extracellular region
0.35	GO:0043234	protein complex
0.34	GO:0035578	azurophil granule lumen
0.33	GO:0005634	nucleus
0.33	GO:0009986	cell surface
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|O35206|COFA1_MOUSE
Collagen alpha-1(XV) chain
Search

COL15A1

0.81	Collagen type XV alpha 1 chain

0.71	GO:0007155	cell adhesion
0.40	GO:0001525	angiogenesis
0.38	GO:0030154	cell differentiation
0.38	GO:2000353	positive regulation of endothelial cell apoptotic process
0.38	GO:0030574	collagen catabolic process
0.38	GO:0003158	endothelium development
0.37	GO:0051270	regulation of cellular component movement
0.37	GO:0040012	regulation of locomotion
0.37	GO:0030198	extracellular matrix organization
0.37	GO:0008284	positive regulation of cell proliferation

0.61	GO:0005198	structural molecule activity
0.33	GO:0017147	Wnt-protein binding
0.33	GO:0042813	Wnt-activated receptor activity
0.32	GO:0042802	identical protein binding
0.32	GO:0004930	G-protein coupled receptor activity
0.32	GO:0046872	metal ion binding

0.77	GO:0005581	collagen trimer
0.73	GO:0031012	extracellular matrix
0.55	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.38	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016020	membrane

sp|O35207|CDKA1_MOUSE
Cyclin-dependent kinase 2-associated protein 1
Search

CDK2AP1

0.95	Cyclin-dependent kinase 2-associated protein 1

0.52	GO:0016310	phosphorylation
0.50	GO:0001934	positive regulation of protein phosphorylation
0.50	GO:2000035	regulation of stem cell division
0.49	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.46	GO:0070507	regulation of microtubule cytoskeleton organization
0.38	GO:0060325	face morphogenesis
0.37	GO:0001701	in utero embryonic development
0.36	GO:0007049	cell cycle
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.56	GO:0070182	DNA polymerase binding
0.54	GO:0016301	kinase activity
0.34	GO:0005509	calcium ion binding
0.34	GO:0005548	phospholipid transporter activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0140096	catalytic activity, acting on a protein

0.51	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.44	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016773

sp|O35214|OPSX_MOUSE
Visual pigment-like receptor peropsin
Search

RRH

0.92	Visual pigment-like receptor peropsin

0.78	GO:0007601	visual perception
0.74	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.40	GO:0009584	detection of visible light
0.40	GO:0007602	phototransduction
0.38	GO:0001522	pseudouridine synthesis
0.37	GO:0042254	ribosome biogenesis

0.78	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.41	GO:0001750	photoreceptor outer segment
0.40	GO:0031429	box H/ACA snoRNP complex
0.35	GO:0005887	integral component of plasma membrane

sp|O35215|DOPD_MOUSE
D-dopachrome decarboxylase
Search

DDT

0.97	D-dopachrome tautomerase like

0.75	GO:0050729	positive regulation of inflammatory response
0.61	GO:0042438	melanin biosynthetic process
0.52	GO:0010760	negative regulation of macrophage chemotaxis
0.50	GO:0032760	positive regulation of tumor necrosis factor production
0.49	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.48	GO:0048839	inner ear development
0.46	GO:0043066	negative regulation of apoptotic process
0.41	GO:0006954	inflammatory response
0.41	GO:0006336	DNA replication-independent nucleosome assembly
0.38	GO:0006749	glutathione metabolic process

0.75	GO:0002020	protease binding
0.67	GO:0033981	D-dopachrome decarboxylase activity
0.53	GO:0050178	phenylpyruvate tautomerase activity
0.48	GO:0004167	dopachrome isomerase activity
0.48	GO:0005126	cytokine receptor binding
0.39	GO:0004364	glutathione transferase activity

0.67	GO:0005615	extracellular space
0.47	GO:1903561	extracellular vesicle
0.41	GO:0005737	cytoplasm

0.67	EC:4.1.1.84	GO:0033981
0.67	KEGG:R07313	GO:0033981

sp|O35216|CENPA_MOUSE
Histone H3-like centromeric protein A
Search

CENPA

0.78	Centromeric protein A

0.50	GO:0051382	kinetochore assembly
0.49	GO:0071459	protein localization to chromosome, centromeric region
0.49	GO:0000132	establishment of mitotic spindle orientation
0.49	GO:0061641	CENP-A containing chromatin organization
0.48	GO:0000281	mitotic cytokinesis
0.45	GO:0006334	nucleosome assembly
0.38	GO:0000819	sister chromatid segregation
0.37	GO:0140014	mitotic nuclear division
0.35	GO:0031055	chromatin remodeling at centromere
0.34	GO:0034724	DNA replication-independent nucleosome organization

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.46	GO:0031491	nucleosome binding
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0003723	RNA binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.54	GO:0000779	condensed chromosome, centromeric region
0.49	GO:0061638	CENP-A containing chromatin
0.49	GO:0000776	kinetochore
0.48	GO:0005721	pericentric heterochromatin
0.47	GO:0031974	membrane-enclosed lumen
0.33	GO:0005829	cytosol
0.33	GO:0000781	chromosome, telomeric region
0.30	GO:0016020	membrane

sp|O35218|CPSF2_MOUSE
Cleavage and polyadenylation specificity factor subunit 2
Search

CPSF2

0.92	Cleavage and polyadenylation specificity factor subunit 2

0.79	GO:0006379	mRNA cleavage
0.78	GO:0006378	mRNA polyadenylation
0.59	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage
0.35	GO:0006369	termination of RNA polymerase II transcription
0.35	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0051028	mRNA transport
0.34	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0006405	RNA export from nucleus
0.32	GO:0055085	transmembrane transport

0.35	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.80	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|O35219|KCNH2_MOUSE
Potassium voltage-gated channel subfamily H member 2
Search

KCNH2

0.57	Potassium voltage-gated channel subfamily H member 2

0.75	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0071804	cellular potassium ion transport
0.61	GO:0098662	inorganic cation transmembrane transport
0.59	GO:0086091	regulation of heart rate by cardiac conduction
0.59	GO:0099625	ventricular cardiac muscle cell membrane repolarization
0.58	GO:0086013	membrane repolarization during cardiac muscle cell action potential
0.58	GO:0086005	ventricular cardiac muscle cell action potential
0.57	GO:0043267	negative regulation of potassium ion transport
0.57	GO:0086010	membrane depolarization during action potential
0.55	GO:0043268	positive regulation of potassium ion transport

0.76	GO:0005249	voltage-gated potassium channel activity
0.59	GO:0055131	C3HC4-type RING finger domain binding
0.56	GO:0097110	scaffold protein binding
0.54	GO:0099094	ligand-gated cation channel activity
0.54	GO:0000155	phosphorelay sensor kinase activity
0.53	GO:0031625	ubiquitin protein ligase binding
0.51	GO:0042803	protein homodimerization activity
0.34	GO:0008237	metallopeptidase activity

0.59	GO:1902937	inward rectifier potassium channel complex
0.53	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0009986	cell surface
0.37	GO:0005635	nuclear envelope

0.54

EC:2.7.3

GO:0000155

sp|O35226|PSMD4_MOUSE
26S proteasome non-ATPase regulatory subunit 4
Search

PSMD4

0.89	26S proteasome non-ATPase regulatory subunit 4

0.66	GO:0006511	ubiquitin-dependent protein catabolic process
0.44	GO:0043248	proteasome assembly
0.43	GO:0010498	proteasomal protein catabolic process
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.36	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.36	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.36	GO:0038095	Fc-epsilon receptor signaling pathway
0.36	GO:1902036	regulation of hematopoietic stem cell differentiation
0.36	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia

0.45	GO:0031593	polyubiquitin modification-dependent protein binding
0.37	GO:0042802	identical protein binding
0.37	GO:0008134	transcription factor binding
0.34	GO:0003723	RNA binding
0.33	GO:0003735	structural constituent of ribosome

0.75	GO:0008540	proteasome regulatory particle, base subcomplex
0.47	GO:0005829	cytosol
0.47	GO:0005654	nucleoplasm
0.33	GO:0005840	ribosome

sp|O35227|ADAM7_MOUSE
Disintegrin and metalloproteinase domain-containing protein 7
Search

ADAM7

0.75	Disintegrin and metalloproteinase domain-containing protein 7

0.60	GO:0006508	proteolysis
0.51	GO:0007229	integrin-mediated signaling pathway
0.37	GO:2000415	positive regulation of fibronectin-dependent thymocyte migration
0.37	GO:2000309	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production
0.37	GO:2000418	positive regulation of eosinophil migration
0.37	GO:0070245	positive regulation of thymocyte apoptotic process
0.37	GO:2000391	positive regulation of neutrophil extravasation
0.36	GO:0033089	positive regulation of T cell differentiation in thymus
0.36	GO:0002523	leukocyte migration involved in inflammatory response
0.36	GO:0045780	positive regulation of bone resorption

0.70	GO:0004222	metalloendopeptidase activity
0.52	GO:0046872	metal ion binding
0.35	GO:0050839	cell adhesion molecule binding
0.35	GO:0090729	toxin activity
0.34	GO:0043015	gamma-tubulin binding
0.32	GO:0003676	nucleic acid binding

0.44	GO:0005886	plasma membrane
0.37	GO:0045177	apical part of cell
0.37	GO:0032127	dense core granule membrane
0.37	GO:0032010	phagolysosome
0.36	GO:0070820	tertiary granule
0.36	GO:0042581	specific granule
0.36	GO:0002102	podosome
0.35	GO:0009986	cell surface
0.34	GO:0005739	mitochondrion
0.34	GO:0000922	spindle pole

0.70

GO:0004222

sp|O35228|IL27B_MOUSE
Interleukin-27 subunit beta
Search

EBI3

0.97	Epstein-Barr virus induced gene 3

0.80	GO:0019221	cytokine-mediated signaling pathway
0.57	GO:0042098	T cell proliferation

0.81	GO:0004896	cytokine receptor activity
0.60	GO:0045523	interleukin-27 receptor binding

0.30

GO:0016020

membrane

sp|O35231|KIFC3_MOUSE
Kinesin-like protein KIFC3
Search

KIFC3

0.65	Kinesin family member C3

0.74	GO:0007018	microtubule-based movement
0.71	GO:0045218	zonula adherens maintenance
0.67	GO:0090136	epithelial cell-cell adhesion
0.63	GO:0007030	Golgi organization

0.85	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.68	GO:0005915	zonula adherens
0.67	GO:0005871	kinesin complex
0.61	GO:0005813	centrosome
0.56	GO:0005794	Golgi apparatus

0.85

EC:3.6.4.5

GO:0008569

sp|O35235|TNF11_MOUSE
Tumor necrosis factor ligand superfamily member 11
Search

TNFSF11

0.97	Tumor necrosis factor ligand superfamily member 11

0.74	GO:0006955	immune response
0.72	GO:0051466	positive regulation of corticotropin-releasing hormone secretion
0.71	GO:0071812	positive regulation of fever generation by positive regulation of prostaglandin secretion
0.71	GO:0071848	positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling
0.71	GO:0002158	osteoclast proliferation
0.70	GO:2001206	positive regulation of osteoclast development
0.70	GO:0034112	positive regulation of homotypic cell-cell adhesion
0.69	GO:0038001	paracrine signaling
0.68	GO:0045780	positive regulation of bone resorption
0.68	GO:0045453	bone resorption

0.83	GO:0005164	tumor necrosis factor receptor binding
0.62	GO:0005125	cytokine activity
0.35	GO:0046872	metal ion binding

0.40	GO:0005622	intracellular
0.40	GO:0005615	extracellular space
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|O35239|PTN9_MOUSE
Tyrosine-protein phosphatase non-receptor type 9
Search

PTPN9

0.95	Tyrosine-protein phosphatase non-receptor type 9

0.73	GO:0035335	peptidyl-tyrosine dephosphorylation
0.47	GO:0043249	erythrocyte maturation
0.46	GO:0060215	primitive hemopoiesis
0.36	GO:1903078	positive regulation of protein localization to plasma membrane
0.36	GO:0010977	negative regulation of neuron projection development
0.35	GO:0071345	cellular response to cytokine stimulus
0.35	GO:0006606	protein import into nucleus

0.73	GO:0004725	protein tyrosine phosphatase activity
0.35	GO:0061608	nuclear import signal receptor activity
0.35	GO:0005515	protein binding

0.59	GO:0044306	neuron projection terminus
0.40	GO:0005737	cytoplasm
0.34	GO:0005654	nucleoplasm

0.73

EC:3.1.3.48

GO:0004725

sp|O35242|FAN_MOUSE
Protein FAN
Search

NSMAF

0.97	Neutral sphingomyelinase activation-associated factor

0.69	GO:0002233	leukocyte chemotaxis involved in immune response
0.66	GO:0002232	leukocyte chemotaxis involved in inflammatory response
0.63	GO:0043065	positive regulation of apoptotic process
0.62	GO:0030593	neutrophil chemotaxis
0.59	GO:0043085	positive regulation of catalytic activity
0.49	GO:2000304	positive regulation of ceramide biosynthetic process
0.46	GO:0006672	ceramide metabolic process
0.39	GO:0007165	signal transduction

0.75	GO:0016230	sphingomyelin phosphodiesterase activator activity
0.49	GO:0005123	death receptor binding
0.45	GO:0005057	signal transducer activity, downstream of receptor

0.42	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|O35245|PKD2_MOUSE
Polycystin-2
Search

PKD2

0.94	Polycystin 2, transient receptor potential cation channel

0.61	GO:0072059	cortical collecting duct development
0.61	GO:0072055	renal cortex development
0.61	GO:0051284	positive regulation of sequestering of calcium ion
0.61	GO:0071464	cellular response to hydrostatic pressure
0.60	GO:0061441	renal artery morphogenesis
0.60	GO:0003127	detection of nodal flow
0.60	GO:0072208	metanephric smooth muscle tissue development
0.60	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
0.60	GO:0072218	metanephric ascending thin limb development
0.60	GO:0035502	metanephric part of ureteric bud development

0.70	GO:0005509	calcium ion binding
0.60	GO:0048763	calcium-induced calcium release activity
0.60	GO:0043398	HLH domain binding
0.58	GO:0015271	outward rectifier potassium channel activity
0.56	GO:0044325	ion channel binding
0.56	GO:0005248	voltage-gated sodium channel activity
0.55	GO:0051117	ATPase binding
0.55	GO:0051219	phosphoprotein binding
0.55	GO:0042805	actinin binding
0.54	GO:0005245	voltage-gated calcium channel activity

0.59	GO:0002133	polycystin complex
0.58	GO:0045180	basal cortex
0.58	GO:0016323	basolateral plasma membrane
0.58	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane
0.58	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane
0.57	GO:0031941	filamentous actin
0.56	GO:0060170	ciliary membrane
0.55	GO:0036064	ciliary basal body
0.55	GO:0030027	lamellipodium
0.55	GO:0097730	non-motile cilium

sp|O35250|EXOC7_MOUSE
Exocyst complex component 7
Search

EXOC7

0.87	Exocyst complex component 7

0.76	GO:0006887	exocytosis
0.48	GO:2000535	regulation of entry of bacterium into host cell
0.34	GO:0015031	protein transport

0.33

GO:0005515

protein binding

0.78	GO:0000145	exocyst
0.48	GO:0032584	growth cone membrane
0.47	GO:0034451	centriolar satellite
0.37	GO:0090543	Flemming body
0.35	GO:0005829	cytosol
0.34	GO:0097546	ciliary base
0.34	GO:0097731	9+0 non-motile cilium

sp|O35253|SMAD7_MOUSE
Mothers against decapentaplegic homolog 7
Search

SMAD7

0.65	Mothers against decapentaplegic homolog

0.76	GO:0007179	transforming growth factor beta receptor signaling pathway
0.60	GO:0010944	negative regulation of transcription by competitive promoter binding
0.60	GO:0034616	response to laminar fluid shear stress
0.60	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation
0.59	GO:2000320	negative regulation of T-helper 17 cell differentiation
0.59	GO:0002725	negative regulation of T cell cytokine production
0.59	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.58	GO:0032925	regulation of activin receptor signaling pathway
0.58	GO:0051444	negative regulation of ubiquitin-protein transferase activity
0.58	GO:0060389	pathway-restricted SMAD protein phosphorylation

0.61	GO:0030617	transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
0.60	GO:0048185	activin binding
0.60	GO:0070411	I-SMAD binding
0.60	GO:0034713	type I transforming growth factor beta receptor binding
0.57	GO:0003700	DNA binding transcription factor activity
0.56	GO:0008013	beta-catenin binding
0.55	GO:0005518	collagen binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0044212	transcription regulatory region DNA binding
0.35	GO:0046872	metal ion binding

0.69	GO:0005667	transcription factor complex
0.58	GO:0016342	catenin complex
0.57	GO:0005634	nucleus
0.56	GO:0005913	cell-cell adherens junction
0.53	GO:0005813	centrosome
0.48	GO:0005829	cytosol
0.48	GO:0070013	intracellular organelle lumen
0.37	GO:0005768	endosome
0.30	GO:0016021	integral component of membrane

sp|O35256|PR4A1_MOUSE
Prolactin-4A1
Search

PRL

0.91

Prolactin

0.76	GO:0010469	regulation of receptor activity
0.53	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II
0.53	GO:0001937	negative regulation of endothelial cell proliferation
0.52	GO:0046427	positive regulation of JAK-STAT cascade
0.52	GO:0040014	regulation of multicellular organism growth
0.47	GO:0007595	lactation
0.44	GO:0001666	response to hypoxia
0.37	GO:0010817	regulation of hormone levels
0.37	GO:0051602	response to electrical stimulus
0.36	GO:0009648	photoperiodism

0.79	GO:0005179	hormone activity
0.41	GO:0005148	prolactin receptor binding
0.36	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.35	GO:0031904	endosome lumen
0.30	GO:0031224	intrinsic component of membrane

sp|O35257|PR6A1_MOUSE
Prolactin-6A1
Search

0.92	Prolactin family 6, subfamily a, member 1

0.76

GO:0010469

regulation of receptor activity

0.79

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

sp|O35261|E2F3_MOUSE
Transcription factor E2F3
Search

E2F3

0.92	Transcription factor E2F

0.70	GO:1905461	positive regulation of vascular associated smooth muscle cell apoptotic process
0.69	GO:0070345	negative regulation of fat cell proliferation
0.63	GO:0006366	transcription by RNA polymerase II
0.63	GO:0045944	positive regulation of transcription by RNA polymerase II
0.60	GO:0008284	positive regulation of cell proliferation
0.52	GO:1990086	lens fiber cell apoptotic process
0.51	GO:1903671	negative regulation of sprouting angiogenesis
0.50	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.45	GO:0051726	regulation of cell cycle

0.68	GO:0001047	core promoter binding
0.68	GO:0046983	protein dimerization activity
0.67	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.65	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.46	GO:0008134	transcription factor binding

0.74	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.50	GO:0044446	intracellular organelle part

sp|O35280|CHK1_MOUSE
Serine/threonine-protein kinase Chk1
Search

CHEK1

0.49	Non-specific serine/threonine protein kinase

0.76	GO:0000077	DNA damage checkpoint
0.63	GO:0006468	protein phosphorylation
0.60	GO:0010767	regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage
0.58	GO:0048096	chromatin-mediated maintenance of transcription
0.57	GO:2000615	regulation of histone H3-K9 acetylation
0.57	GO:0007093	mitotic cell cycle checkpoint
0.57	GO:1902742	apoptotic process involved in development
0.56	GO:0018210	peptidyl-threonine modification
0.56	GO:0000086	G2/M transition of mitotic cell cycle
0.55	GO:0001833	inner cell mass cell proliferation

0.67	GO:0004674	protein serine/threonine kinase activity
0.58	GO:0035173	histone kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0019904	protein domain specific binding
0.36	GO:0004576	oligosaccharyl transferase activity
0.33	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors

0.50	GO:0005657	replication fork
0.50	GO:0000785	chromatin
0.49	GO:0005654	nucleoplasm
0.40	GO:0000794	condensed nuclear chromosome
0.40	GO:0005813	centrosome
0.38	GO:0000781	chromosome, telomeric region
0.37	GO:0005737	cytoplasm
0.36	GO:0005615	extracellular space
0.35	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.67

GO:0004674

sp|O35284|BATF_MOUSE
Basic leucine zipper transcriptional factor ATF-like
Search

BATF

0.97	Basic leucine zipper transcriptional factor ATF

0.71	GO:0030154	cell differentiation
0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.69	GO:0072538	T-helper 17 type immune response
0.69	GO:0042092	type 2 immune response
0.68	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response
0.68	GO:0042832	defense response to protozoan
0.68	GO:0001773	myeloid dendritic cell activation
0.67	GO:0002287	alpha-beta T cell activation involved in immune response
0.67	GO:0035710	CD4-positive, alpha-beta T cell activation
0.67	GO:0002312	B cell activation involved in immune response

0.62	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.61	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0005515	protein binding

0.55	GO:0005654	nucleoplasm
0.42	GO:0005737	cytoplasm

sp|O35286|DHX15_MOUSE
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15
Search

DHX15

0.81	DEAH (Asp-Glu-Ala-His) box polypeptide 15

0.48	GO:0000398	mRNA splicing, via spliceosome
0.44	GO:0043279	response to alkaloid
0.39	GO:0009636	response to toxic substance

0.67	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0003725	double-stranded RNA binding
0.49	GO:0008186	RNA-dependent ATPase activity
0.43	GO:0140098	catalytic activity, acting on RNA

0.58	GO:0071008	U2-type post-mRNA release spliceosomal complex
0.58	GO:0005689	U12-type spliceosomal complex
0.55	GO:0016607	nuclear speck
0.38	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|O35290|ECP3_MOUSE
Eosinophil cationic-type ribonuclease 3
Search

0.97	Non-secretory ribonuclease

0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.43	GO:0098542	defense response to other organism
0.43	GO:0016070	RNA metabolic process
0.43	GO:0002252	immune effector process
0.42	GO:0009615	response to virus
0.42	GO:1903955	positive regulation of protein targeting to mitochondrion
0.41	GO:0019730	antimicrobial humoral response
0.40	GO:0006935	chemotaxis
0.39	GO:0009617	response to bacterium
0.38	GO:0002227	innate immune response in mucosa

0.65	GO:0004519	endonuclease activity
0.51	GO:0003676	nucleic acid binding
0.50	GO:0004540	ribonuclease activity
0.41	GO:0001530	lipopolysaccharide binding

0.44	GO:0005764	lysosome
0.40	GO:0070062	extracellular exosome
0.37	GO:0030141	secretory granule
0.36	GO:0060205	cytoplasmic vesicle lumen
0.36	GO:0005775	vacuolar lumen
0.30	GO:0031224	intrinsic component of membrane

sp|O35291|RNAS2_MOUSE
Non-secretory ribonuclease
Search

0.97	Non-secretory ribonuclease

0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.44	GO:0098542	defense response to other organism
0.44	GO:0002252	immune effector process
0.43	GO:0009615	response to virus
0.43	GO:0016070	RNA metabolic process
0.43	GO:1903955	positive regulation of protein targeting to mitochondrion
0.42	GO:0019730	antimicrobial humoral response
0.40	GO:0006935	chemotaxis
0.40	GO:0009617	response to bacterium
0.39	GO:0002227	innate immune response in mucosa

0.65	GO:0004519	endonuclease activity
0.51	GO:0004540	ribonuclease activity
0.51	GO:0003676	nucleic acid binding
0.41	GO:0001530	lipopolysaccharide binding

0.46	GO:0005764	lysosome
0.40	GO:0070062	extracellular exosome
0.37	GO:0030141	secretory granule
0.37	GO:0060205	cytoplasmic vesicle lumen
0.37	GO:0005775	vacuolar lumen
0.30	GO:0031224	intrinsic component of membrane

sp|O35292|RNS2B_MOUSE
Ribonuclease 2B
Search

0.97	Non-secretory ribonuclease

0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.46	GO:0098542	defense response to other organism
0.45	GO:0002376	immune system process
0.43	GO:0009617	response to bacterium
0.43	GO:0016070	RNA metabolic process
0.42	GO:0009615	response to virus
0.42	GO:1903955	positive regulation of protein targeting to mitochondrion
0.41	GO:0009620	response to fungus
0.39	GO:0006935	chemotaxis
0.38	GO:0051673	membrane disruption in other organism

0.65	GO:0004519	endonuclease activity
0.51	GO:0004540	ribonuclease activity
0.51	GO:0003676	nucleic acid binding
0.43	GO:0001530	lipopolysaccharide binding
0.38	GO:0042834	peptidoglycan binding

0.44	GO:0005764	lysosome
0.42	GO:0005576	extracellular region
0.39	GO:0031982	vesicle
0.36	GO:0005775	vacuolar lumen
0.35	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

sp|O35295|PURB_MOUSE
Transcriptional activator protein Pur-beta
Search

0.95	Transcriptional activator protein Pur-beta-A

0.75	GO:0008283	cell proliferation
0.71	GO:0030154	cell differentiation
0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.49	GO:0042127	regulation of cell proliferation
0.45	GO:0006357	regulation of transcription by RNA polymerase II
0.42	GO:0006268	DNA unwinding involved in DNA replication
0.41	GO:0017148	negative regulation of translation
0.40	GO:0007399	nervous system development
0.38	GO:0048522	positive regulation of cellular process
0.37	GO:0006351	transcription, DNA-templated

0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0003677	DNA binding
0.53	GO:0046332	SMAD binding
0.49	GO:0001067	regulatory region nucleic acid binding
0.48	GO:0008134	transcription factor binding
0.46	GO:0003729	mRNA binding
0.44	GO:0000900	translation repressor activity, nucleic acid binding
0.34	GO:0015002	heme-copper terminal oxidase activity
0.34	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.34	GO:0015078	hydrogen ion transmembrane transporter activity

0.54	GO:0005662	DNA replication factor A complex
0.41	GO:0043025	neuronal cell body
0.41	GO:0030425	dendrite
0.35	GO:0005737	cytoplasm
0.33	GO:0031967	organelle envelope
0.33	GO:0000786	nucleosome
0.33	GO:0016459	myosin complex
0.33	GO:0000784	nuclear chromosome, telomeric region
0.30	GO:0016020	membrane

0.34

EC:1.9

GO:0016675

sp|O35298|AOAH_MOUSE
Acyloxyacyl hydrolase
Search

AOAH

0.93	Acyloxyacyl hydrolase

0.54	GO:0050728	negative regulation of inflammatory response
0.49	GO:0008653	lipopolysaccharide metabolic process
0.35	GO:0006643	membrane lipid metabolic process
0.35	GO:0006954	inflammatory response
0.34	GO:0006497	protein lipidation
0.34	GO:0006661	phosphatidylinositol biosynthetic process
0.33	GO:1901137	carbohydrate derivative biosynthetic process

0.61

GO:0016788

hydrolase activity, acting on ester bonds

0.38	GO:0031410	cytoplasmic vesicle
0.37	GO:0005576	extracellular region
0.35	GO:0005764	lysosome
0.30	GO:0016020	membrane

0.61

EC:3.1

GO:0016788

sp|O35304|VACHT_MOUSE
Vesicular acetylcholine transporter
Search

SLC18A3

0.95	Vesicular acetylcholine transporter

0.57	GO:0006855	drug transmembrane transport
0.51	GO:1901374	acetate ester transport
0.46	GO:0006836	neurotransmitter transport
0.46	GO:0072488	ammonium transmembrane transport
0.46	GO:0015695	organic cation transport
0.36	GO:0015844	monoamine transport
0.35	GO:0099643	signal release from synapse
0.35	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.34	GO:0001505	regulation of neurotransmitter levels
0.34	GO:0051649	establishment of localization in cell

0.56	GO:0015238	drug transmembrane transporter activity
0.51	GO:1901375	acetate ester transmembrane transporter activity
0.50	GO:0042166	acetylcholine binding
0.47	GO:0015101	organic cation transmembrane transporter activity
0.46	GO:0005326	neurotransmitter transporter activity
0.46	GO:0008519	ammonium transmembrane transporter activity
0.41	GO:0016746	transferase activity, transferring acyl groups
0.36	GO:0008504	monoamine transmembrane transporter activity
0.34	GO:0005515	protein binding

0.49	GO:0030121	AP-1 adaptor complex
0.48	GO:0030122	AP-2 adaptor complex
0.42	GO:0060200	clathrin-sculpted acetylcholine transport vesicle
0.42	GO:0005887	integral component of plasma membrane
0.39	GO:0098793	presynapse
0.38	GO:0044306	neuron projection terminus
0.38	GO:0033267	axon part
0.35	GO:0070382	exocytic vesicle

0.41

EC:2.3

GO:0016746

sp|O35305|TNR11_MOUSE
Tumor necrosis factor receptor superfamily member 11A
Search

TNFRSF11A

0.96	Tumor necrosis factor receptor superfamily member 11A

0.74	GO:0060086	circadian temperature homeostasis
0.74	GO:0071848	positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling
0.74	GO:0071812	positive regulation of fever generation by positive regulation of prostaglandin secretion
0.71	GO:0048535	lymph node development
0.70	GO:0060749	mammary gland alveolus development
0.70	GO:0032496	response to lipopolysaccharide
0.70	GO:0030316	osteoclast differentiation
0.68	GO:0043507	positive regulation of JUN kinase activity
0.68	GO:0070555	response to interleukin-1
0.67	GO:0051092	positive regulation of NF-kappaB transcription factor activity

0.75	GO:0005031	tumor necrosis factor-activated receptor activity
0.67	GO:0019955	cytokine binding
0.36	GO:0046872	metal ion binding
0.33	GO:0001618	virus receptor activity

0.65	GO:0009897	external side of plasma membrane
0.56	GO:0005829	cytosol
0.49	GO:0005887	integral component of plasma membrane

sp|O35308|MOT3_MOUSE
Monocarboxylate transporter 3
Search

SLC16A3

0.92	Proton-coupled monocarboxylate transporter 3

0.81	GO:0035873	lactate transmembrane transport
0.34	GO:0050900	leukocyte migration
0.33	GO:0006090	pyruvate metabolic process

0.81	GO:0015129	lactate transmembrane transporter activity
0.39	GO:0015293	symporter activity
0.36	GO:0015355	secondary active monocarboxylate transmembrane transporter activity
0.33	GO:0003723	RNA binding

0.67	GO:0005887	integral component of plasma membrane
0.52	GO:0031965	nuclear membrane
0.36	GO:0009925	basal plasma membrane

sp|O35309|NMI_MOUSE
N-myc-interactor
Search

NMI

0.89	N-myc and STAT interactor

0.86	GO:0060333	interferon-gamma-mediated signaling pathway
0.76	GO:0006366	transcription by RNA polymerase II
0.70	GO:0045355	negative regulation of interferon-alpha biosynthetic process
0.70	GO:0045358	negative regulation of interferon-beta biosynthetic process
0.69	GO:1902524	positive regulation of protein K48-linked ubiquitination
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0045824	negative regulation of innate immune response
0.39	GO:0007259	JAK-STAT cascade
0.38	GO:0006954	inflammatory response

0.76	GO:0003712	transcription cofactor activity
0.57	GO:0042802	identical protein binding
0.37	GO:0003676	nucleic acid binding

0.54	GO:0005654	nucleoplasm
0.53	GO:0005829	cytosol

sp|O35310|HS3S1_MOUSE
Heparan sulfate glucosamine 3-O-sulfotransferase 1
Search

HS3ST1

0.54	Sulfotransferase

0.45	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification
0.45	GO:0046596	regulation of viral entry into host cell
0.44	GO:0050819	negative regulation of coagulation
0.43	GO:0006477	protein sulfation
0.39	GO:0060271	cilium assembly
0.37	GO:0055003	cardiac myofibril assembly
0.36	GO:0045214	sarcomere organization
0.36	GO:0060047	heart contraction
0.33	GO:0006313	transposition, DNA-mediated
0.33	GO:0015074	DNA integration

0.77	GO:0008146	sulfotransferase activity
0.32	GO:0003677	DNA binding

0.30

GO:0016020

membrane

0.77

GO:0008146

sp|O35316|SC6A6_MOUSE
Sodium- and chloride-dependent taurine transporter
Search

SLC6A6

0.46	Sodium- and chloride-dependent taurine transporter

0.82	GO:0015734	taurine transport
0.76	GO:0006836	neurotransmitter transport
0.54	GO:0055085	transmembrane transport
0.42	GO:0006865	amino acid transport
0.33	GO:0006520	cellular amino acid metabolic process

0.86	GO:0005369	taurine:sodium symporter activity
0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.36	GO:0043210	alkanesulfonate binding
0.34	GO:0015171	amino acid transmembrane transporter activity

0.66

GO:0005887

integral component of plasma membrane

sp|O35317|PBX3_MOUSE
Pre-B-cell leukemia transcription factor 3
Search

PBX3

0.90	PBX homeobox 3

0.71	GO:0002087	regulation of respiratory gaseous exchange by neurological system process
0.70	GO:0021516	dorsal spinal cord development
0.69	GO:0007585	respiratory gaseous exchange
0.67	GO:0008344	adult locomotory behavior
0.62	GO:0048666	neuron development
0.61	GO:0006366	transcription by RNA polymerase II
0.61	GO:0045944	positive regulation of transcription by RNA polymerase II

0.70	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.69	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.61	GO:0005667	transcription factor complex

sp|O35324|SH21B_MOUSE
SH2 domain-containing protein 1B
Search

SH2D1B

0.88	SH2 domain containing 1A duplicate b

0.66	GO:0046856	phosphatidylinositol dephosphorylation
0.53	GO:0002717	positive regulation of natural killer cell mediated immunity
0.51	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity
0.50	GO:0001912	positive regulation of leukocyte mediated cytotoxicity
0.48	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.47	GO:0002250	adaptive immune response
0.46	GO:0032814	regulation of natural killer cell activation
0.46	GO:0018108	peptidyl-tyrosine phosphorylation
0.46	GO:0045087	innate immune response
0.45	GO:0009967	positive regulation of signal transduction

0.48	GO:0060090	molecular adaptor activity
0.45	GO:0016787	hydrolase activity
0.44	GO:0005515	protein binding
0.34	GO:0004713	protein tyrosine kinase activity
0.34	GO:0004601	peroxidase activity
0.33	GO:0020037	heme binding
0.32	GO:0005524	ATP binding

0.40	GO:0005622	intracellular
0.36	GO:0030175	filopodium
0.36	GO:0030027	lamellipodium
0.34	GO:0012505	endomembrane system
0.33	GO:0043226	organelle
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.45	EC:3	GO:0016787
0.34	KEGG:R03532	GO:0004601

sp|O35326|SRSF5_MOUSE
Serine/arginine-rich splicing factor 5
Search

SRSF5

0.97	Serine and arginine rich splicing factor 5

0.41	GO:0097421	liver regeneration
0.40	GO:0033120	positive regulation of RNA splicing
0.40	GO:0032869	cellular response to insulin stimulus
0.38	GO:0051726	regulation of cell cycle
0.37	GO:0008380	RNA splicing
0.36	GO:0009611	response to wounding
0.36	GO:0006397	mRNA processing
0.35	GO:0006369	termination of RNA polymerase II transcription
0.35	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0031123	RNA 3'-end processing

0.59	GO:0003723	RNA binding
0.41	GO:0043422	protein kinase B binding
0.38	GO:0050733	RS domain binding

0.52	GO:0005730	nucleolus
0.50	GO:0005829	cytosol
0.38	GO:0016607	nuclear speck
0.34	GO:0005882	intermediate filament

sp|O35343|IMA3_MOUSE
Importin subunit alpha-3
Search

KPNA4

0.60	Importin subunit alpha

0.79	GO:0006606	protein import into nucleus
0.52	GO:0042542	response to hydrogen peroxide
0.35	GO:0075733	intracellular transport of virus
0.35	GO:0044068	modulation by symbiont of host cellular process
0.34	GO:0019048	modulation by virus of host morphology or physiology
0.34	GO:1902594	multi-organism nuclear import
0.33	GO:0006461	protein complex assembly
0.33	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.33	GO:0044409	entry into host

0.82	GO:0061608	nuclear import signal receptor activity
0.69	GO:0008565	protein transporter activity
0.48	GO:0008139	nuclear localization sequence binding
0.42	GO:0008022	protein C-terminus binding

0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.47	GO:0012505	endomembrane system
0.45	GO:0031967	organelle envelope
0.43	GO:0031090	organelle membrane
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0043234	protein complex
0.36	GO:0070062	extracellular exosome
0.34	GO:0044216	other organism cell
0.34	GO:0018995	host

sp|O35344|IMA4_MOUSE
Importin subunit alpha-4
Search

KPNA3

0.60	Importin subunit alpha

0.79	GO:0006606	protein import into nucleus
0.44	GO:0042542	response to hydrogen peroxide
0.35	GO:0016125	sterol metabolic process
0.35	GO:0075733	intracellular transport of virus
0.35	GO:0044068	modulation by symbiont of host cellular process
0.34	GO:0019048	modulation by virus of host morphology or physiology
0.34	GO:1902594	multi-organism nuclear import
0.33	GO:0006461	protein complex assembly
0.33	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.33	GO:0044409	entry into host

0.82	GO:0061608	nuclear import signal receptor activity
0.65	GO:0008565	protein transporter activity
0.53	GO:0008022	protein C-terminus binding
0.49	GO:0008139	nuclear localization sequence binding
0.36	GO:0047750	cholestenol delta-isomerase activity

0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.45	GO:0012505	endomembrane system
0.43	GO:0031967	organelle envelope
0.42	GO:0031974	membrane-enclosed lumen
0.40	GO:0043234	protein complex
0.38	GO:0031090	organelle membrane
0.34	GO:0070062	extracellular exosome
0.34	GO:0044217	other organism part
0.34	GO:0018995	host

0.36

EC:5.3.3.5

GO:0047750

sp|O35345|IMA7_MOUSE
Importin subunit alpha-7
Search

KPNA6

0.61	Importin subunit alpha

0.80	GO:0006606	protein import into nucleus
0.53	GO:0060135	maternal process involved in female pregnancy
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.33	GO:0075733	intracellular transport of virus
0.33	GO:0044068	modulation by symbiont of host cellular process
0.33	GO:0019048	modulation by virus of host morphology or physiology

0.83	GO:0061608	nuclear import signal receptor activity
0.70	GO:0008565	protein transporter activity
0.51	GO:0008139	nuclear localization sequence binding
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.44	GO:0012505	endomembrane system
0.44	GO:0043233	organelle lumen
0.42	GO:0031967	organelle envelope
0.41	GO:0043234	protein complex
0.33	GO:0044216	other organism cell
0.33	GO:0018995	host
0.30	GO:0016020	membrane

sp|O35347|DGCR6_MOUSE
Protein DGCR6
Search

DGCR6

0.97	DiGeorge syndrome critical region gene 6

0.53	GO:0032501	multicellular organismal process
0.50	GO:0007155	cell adhesion
0.50	GO:0009653	anatomical structure morphogenesis
0.48	GO:0009593	detection of chemical stimulus
0.46	GO:0007186	G-protein coupled receptor signaling pathway

0.48	GO:0004984	olfactory receptor activity
0.46	GO:0004930	G-protein coupled receptor activity
0.45	GO:0005515	protein binding

0.51	GO:0005578	proteinaceous extracellular matrix
0.51	GO:0005634	nucleus
0.40	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|O35348|COLQ_MOUSE
Acetylcholinesterase collagenic tail peptide
Search

COLQ

0.91	Collagen like tail subunit of asymmetric acetylcholinesterase

0.79	GO:0071340	skeletal muscle acetylcholine-gated channel clustering
0.75	GO:0008582	regulation of synaptic growth at neuromuscular junction
0.64	GO:0090150	establishment of protein localization to membrane
0.44	GO:0042135	neurotransmitter catabolic process
0.40	GO:0008291	acetylcholine metabolic process
0.40	GO:0007271	synaptic transmission, cholinergic
0.38	GO:0042447	hormone catabolic process
0.37	GO:0042737	drug catabolic process
0.36	GO:1901575	organic substance catabolic process
0.34	GO:0019395	fatty acid oxidation

0.40	GO:1901681	sulfur compound binding
0.38	GO:0005515	protein binding
0.38	GO:0005539	glycosaminoglycan binding
0.37	GO:0019842	vitamin binding
0.37	GO:0000287	magnesium ion binding
0.36	GO:0050662	coenzyme binding
0.36	GO:0043168	anion binding
0.36	GO:0005198	structural molecule activity
0.35	GO:0016829	lyase activity
0.33	GO:1901363	heterocyclic compound binding

0.73	GO:0031594	neuromuscular junction
0.66	GO:0030054	cell junction
0.61	GO:0005581	collagen trimer
0.51	GO:0005886	plasma membrane
0.44	GO:0005605	basal lamina
0.40	GO:0043083	synaptic cleft
0.37	GO:0005615	extracellular space
0.34	GO:0005777	peroxisome
0.30	GO:0016021	integral component of membrane

0.35

EC:4

GO:0016829

sp|O35350|CAN1_MOUSE
Calpain-1 catalytic subunit
Search

CAPN1

0.86	Micromolar calcium-activated neutral protease 1 large subunit

0.61	GO:0006508	proteolysis
0.54	GO:0060056	mammary gland involution
0.49	GO:0032801	receptor catabolic process
0.47	GO:0050790	regulation of catalytic activity
0.39	GO:0051493	regulation of cytoskeleton organization
0.36	GO:0030154	cell differentiation
0.35	GO:2000310	regulation of NMDA receptor activity
0.35	GO:0022617	extracellular matrix disassembly
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0016241	regulation of macroautophagy

0.82	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.70	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.33	GO:0003887	DNA-directed DNA polymerase activity
0.32	GO:0003677	DNA binding
0.32	GO:0022857	transmembrane transporter activity

0.49	GO:0005764	lysosome
0.47	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.42	GO:0005886	plasma membrane
0.39	GO:0030141	secretory granule
0.38	GO:0097223	sperm part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0031143	pseudopodium
0.34	GO:0097038	perinuclear endoplasmic reticulum

0.33

GO:0003887

sp|O35367|KERA_MOUSE
Keratocan
Search

KERA

0.97

Keratocan

0.76	GO:0061303	cornea development in camera-type eye
0.55	GO:0007409	axonogenesis
0.44	GO:0007569	cell aging
0.41	GO:0007601	visual perception
0.39	GO:0042340	keratan sulfate catabolic process
0.39	GO:0030199	collagen fibril organization
0.39	GO:0018146	keratan sulfate biosynthetic process
0.35	GO:0050896	response to stimulus

0.62	GO:0005201	extracellular matrix structural constituent
0.38	GO:0008201	heparin binding
0.35	GO:0005518	collagen binding
0.34	GO:0005509	calcium ion binding

0.67	GO:0005578	proteinaceous extracellular matrix
0.54	GO:0005615	extracellular space
0.38	GO:0043202	lysosomal lumen
0.38	GO:0005796	Golgi lumen
0.37	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|O35368|IFI3_MOUSE
Interferon-activable protein 203
Search

0.96	Myeloid cell nuclear differentiation antigen

0.66	GO:0048584	positive regulation of response to stimulus
0.66	GO:0035458	cellular response to interferon-beta
0.65	GO:0045862	positive regulation of proteolysis
0.65	GO:0032731	positive regulation of interleukin-1 beta production
0.61	GO:0002684	positive regulation of immune system process
0.61	GO:2000116	regulation of cysteine-type endopeptidase activity
0.61	GO:0044093	positive regulation of molecular function
0.61	GO:0012501	programmed cell death
0.60	GO:0048519	negative regulation of biological process
0.60	GO:0051101	regulation of DNA binding

0.62	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.61	GO:0003690	double-stranded DNA binding
0.61	GO:0001047	core promoter binding
0.59	GO:0042802	identical protein binding
0.58	GO:0001012	RNA polymerase II regulatory region DNA binding
0.55	GO:0008134	transcription factor binding
0.51	GO:0031625	ubiquitin protein ligase binding
0.50	GO:0043565	sequence-specific DNA binding
0.39	GO:0003712	transcription cofactor activity
0.35	GO:0003723	RNA binding

0.63	GO:0031981	nuclear lumen
0.59	GO:0097169	AIM2 inflammasome complex
0.50	GO:0043232	intracellular non-membrane-bounded organelle
0.45	GO:0005739	mitochondrion
0.41	GO:0042405	nuclear inclusion body
0.30	GO:0016020	membrane

sp|O35372|CNIH1_MOUSE
Protein cornichon homolog 1
Search

CNIH1

0.92	Putative er vesicle integral membrane protein involved in establishing cell polarity signaling

0.69	GO:0016192	vesicle-mediated transport
0.41	GO:0007310	oocyte dorsal/ventral axis specification
0.41	GO:0046843	dorsal appendage formation
0.40	GO:0007350	blastoderm segmentation
0.39	GO:0009952	anterior/posterior pattern specification
0.38	GO:0046907	intracellular transport
0.35	GO:0008314	gurken signaling pathway
0.34	GO:0051650	establishment of vesicle localization
0.34	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation
0.34	GO:0016050	vesicle organization

0.35	GO:0003779	actin binding
0.34	GO:0071933	Arp2/3 complex binding

0.40	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0000139	Golgi membrane
0.35	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.34	GO:0012507	ER to Golgi transport vesicle membrane
0.30	GO:0031224	intrinsic component of membrane

sp|O35375|NRP2_MOUSE
Neuropilin-2
Search

NRP2

0.91	Neuropilin

0.85	GO:0038084	vascular endothelial growth factor signaling pathway
0.83	GO:0071526	semaphorin-plexin signaling pathway
0.82	GO:0001525	angiogenesis
0.81	GO:0007411	axon guidance
0.55	GO:0001755	neural crest cell migration
0.50	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway
0.49	GO:0001570	vasculogenesis
0.48	GO:1904835	dorsal root ganglion morphogenesis
0.48	GO:0021649	vestibulocochlear nerve structural organization
0.48	GO:0021612	facial nerve structural organization

0.85	GO:0005021	vascular endothelial growth factor-activated receptor activity
0.84	GO:0017154	semaphorin receptor activity
0.53	GO:0046872	metal ion binding
0.38	GO:0005515	protein binding
0.30	GO:0008201	heparin binding

0.44	GO:0030424	axon
0.30	GO:0016020	membrane
0.30	GO:0071944	cell periphery

sp|O35379|MRP1_MOUSE
Multidrug resistance-associated protein 1
Search

ABCC1

0.80	LOW QUALITY PROTEIN: multidrug resistance-associated protein 1

0.55	GO:0055085	transmembrane transport
0.48	GO:0099039	sphingolipid translocation
0.45	GO:0042908	xenobiotic transport
0.45	GO:0034635	glutathione transport
0.44	GO:0045332	phospholipid translocation
0.42	GO:0015893	drug transport
0.41	GO:0071585	detoxification of cadmium ion
0.37	GO:1905701	positive regulation of drug transmembrane export
0.37	GO:0060326	cell chemotaxis
0.36	GO:0033700	phospholipid efflux

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0046623	sphingolipid-translocating ATPase activity
0.48	GO:0034634	glutathione transmembrane transporter activity
0.45	GO:0042910	xenobiotic transmembrane transporter activity
0.44	GO:0004012	phospholipid-translocating ATPase activity
0.43	GO:0015238	drug transmembrane transporter activity
0.35	GO:0005324	long-chain fatty acid transporter activity

0.50	GO:0016323	basolateral plasma membrane
0.44	GO:0005887	integral component of plasma membrane
0.37	GO:0070062	extracellular exosome
0.32	GO:0005737	cytoplasm

0.44	EC:3.6.3.1	GO:0004012
0.34	KEGG:R04371	GO:0004409

sp|O35381|AN32A_MOUSE
Acidic leucine-rich nuclear phosphoprotein 32 family member A
Search

ANP32A

0.91	Acidic leucine-rich nuclear phosphoprotein 32 family member A

0.71	GO:0006913	nucleocytoplasmic transport
0.69	GO:0043486	histone exchange
0.66	GO:0006334	nucleosome assembly
0.62	GO:0042981	regulation of apoptotic process
0.45	GO:0006351	transcription, DNA-templated
0.45	GO:2001141	regulation of RNA biosynthetic process
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:0035067	negative regulation of histone acetylation
0.44	GO:0010468	regulation of gene expression
0.44	GO:0010977	negative regulation of neuron projection development

0.66	GO:0042393	histone binding
0.44	GO:0005178	integrin binding
0.43	GO:0008022	protein C-terminus binding
0.40	GO:0003723	RNA binding

0.74	GO:0048471	perinuclear region of cytoplasm
0.66	GO:0005783	endoplasmic reticulum
0.61	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.40	GO:0005829	cytosol

sp|O35382|EXOC4_MOUSE
Exocyst complex component 4
Search

EXOC4

0.91	Exocyst complex component 4

0.80	GO:0006904	vesicle docking involved in exocytosis
0.65	GO:0015031	protein transport
0.61	GO:0048341	paraxial mesoderm formation
0.51	GO:0006903	vesicle targeting
0.51	GO:0006893	Golgi to plasma membrane transport
0.48	GO:0007268	chemical synaptic transmission
0.47	GO:0090150	establishment of protein localization to membrane
0.45	GO:0046907	intracellular transport
0.37	GO:0050850	positive regulation of calcium-mediated signaling
0.37	GO:0048709	oligodendrocyte differentiation

0.60	GO:0017160	Ral GTPase binding
0.59	GO:0047485	protein N-terminus binding
0.58	GO:0030165	PDZ domain binding
0.37	GO:0030742	GTP-dependent protein binding
0.36	GO:0032403	protein complex binding

0.78	GO:0000145	exocyst
0.63	GO:0032584	growth cone membrane
0.61	GO:0035748	myelin sheath abaxonal region
0.58	GO:0005902	microvillus
0.48	GO:0045202	synapse
0.42	GO:0090543	Flemming body
0.37	GO:0043198	dendritic shaft
0.36	GO:0043025	neuronal cell body
0.36	GO:0031252	cell leading edge
0.36	GO:0005768	endosome

sp|O35385|PPE2_MOUSE
Serine/threonine-protein phosphatase with EF-hands 2
Search

0.54	Serine/threonine-protein phosphatase with EF-hands 2

0.73	GO:0050906	detection of stimulus involved in sensory perception
0.71	GO:0006470	protein dephosphorylation
0.56	GO:0010801	negative regulation of peptidyl-threonine phosphorylation
0.55	GO:0043409	negative regulation of MAPK cascade
0.38	GO:0007601	visual perception
0.36	GO:0043506	regulation of JUN kinase activity

0.71	GO:0004721	phosphoprotein phosphatase activity
0.71	GO:0030145	manganese ion binding
0.69	GO:0005509	calcium ion binding
0.61	GO:0005506	iron ion binding
0.59	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.58	GO:0051879	Hsp90 protein binding
0.58	GO:0030544	Hsp70 protein binding

0.36	GO:0001917	photoreceptor inner segment
0.36	GO:0001750	photoreceptor outer segment
0.32	GO:0005737	cytoplasm

0.71

GO:0004721

sp|O35386|PAHX_MOUSE
Phytanoyl-CoA dioxygenase, peroxisomal
Search

PHYH

0.92	LOW QUALITY PROTEIN: phytanoyl-CoA dioxygenase, peroxisomal

0.67	GO:0001561	fatty acid alpha-oxidation
0.60	GO:0097089	methyl-branched fatty acid metabolic process
0.54	GO:0006103	2-oxoglutarate metabolic process
0.49	GO:0006720	isoprenoid metabolic process
0.33	GO:0055085	transmembrane transport

0.69	GO:0051213	dioxygenase activity
0.53	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.53	GO:0008198	ferrous iron binding
0.50	GO:0043177	organic acid binding
0.42	GO:0048037	cofactor binding
0.41	GO:0043168	anion binding
0.40	GO:0048029	monosaccharide binding
0.38	GO:0019842	vitamin binding
0.35	GO:0005515	protein binding
0.33	GO:0005215	transporter activity

0.52	GO:0005777	peroxisome
0.44	GO:0005739	mitochondrion
0.36	GO:0031907	microbody lumen
0.30	GO:0016020	membrane

0.53

EC:1.14

GO:0016705

sp|O35387|HAX1_MOUSE
HCLS1-associated protein X-1
Search

HAX1

0.97	HCLS1-associated protein X-1

0.73	GO:0030854	positive regulation of granulocyte differentiation
0.71	GO:2000251	positive regulation of actin cytoskeleton reorganization
0.69	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.69	GO:0051897	positive regulation of protein kinase B signaling
0.68	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.67	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.64	GO:0071345	cellular response to cytokine stimulus
0.63	GO:0043066	negative regulation of apoptotic process
0.63	GO:0030833	regulation of actin filament polymerization
0.61	GO:0045944	positive regulation of transcription by RNA polymerase II

0.72	GO:0019966	interleukin-1 binding
0.69	GO:0047485	protein N-terminus binding
0.37	GO:0004012	phospholipid-translocating ATPase activity
0.37	GO:0019904	protein domain specific binding
0.35	GO:0000287	magnesium ion binding
0.34	GO:0004896	cytokine receptor activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0022803	passive transmembrane transporter activity

0.83	GO:0016529	sarcoplasmic reticulum
0.77	GO:0031965	nuclear membrane
0.70	GO:0031410	cytoplasmic vesicle
0.65	GO:0030027	lamellipodium
0.64	GO:0005758	mitochondrial intermembrane space
0.63	GO:0005741	mitochondrial outer membrane
0.61	GO:0005667	transcription factor complex
0.59	GO:0015629	actin cytoskeleton
0.45	GO:0000932	P-body
0.43	GO:0005938	cell cortex

0.37

EC:3.6.3.1

GO:0004012

sp|O35392|FOXD2_MOUSE
Forkhead box protein D2
Search

FOXD2

0.92	Forkhead box protein D2

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:1902680	positive regulation of RNA biosynthetic process
0.49	GO:0030154	cell differentiation
0.49	GO:0009653	anatomical structure morphogenesis
0.43	GO:0072127	renal capsule development
0.42	GO:0072076	nephrogenic mesenchyme development
0.42	GO:0072268	pattern specification involved in metanephros development
0.42	GO:0032275	luteinizing hormone secretion

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.42	GO:0001012	RNA polymerase II regulatory region DNA binding
0.41	GO:0008301	DNA binding, bending
0.41	GO:0003690	double-stranded DNA binding
0.32	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.37	GO:0000785	chromatin
0.36	GO:0043233	organelle lumen
0.32	GO:0005667	transcription factor complex

sp|O35393|EFNB3_MOUSE
Ephrin-B3
Search

0.68	GO:0048013	ephrin receptor signaling pathway
0.61	GO:0031295	T cell costimulation
0.58	GO:0016198	axon choice point recognition
0.58	GO:0010977	negative regulation of neuron projection development
0.57	GO:0007628	adult walking behavior
0.56	GO:0010771	negative regulation of cell morphogenesis involved in differentiation
0.55	GO:0050770	regulation of axonogenesis
0.44	GO:0048513	animal organ development
0.44	GO:0001667	ameboidal-type cell migration
0.43	GO:0009888	tissue development

0.70	GO:0046875	ephrin receptor binding
0.37	GO:0001618	virus receptor activity
0.36	GO:0005005	transmembrane-ephrin receptor activity
0.36	GO:0003777	microtubule motor activity
0.34	GO:0016887	ATPase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008144	drug binding

0.45	GO:0005886	plasma membrane
0.40	GO:0098857	membrane microdomain
0.36	GO:0005634	nucleus
0.35	GO:0005925	focal adhesion
0.35	GO:0030286	dynein complex
0.34	GO:0005737	cytoplasm
0.33	GO:0070062	extracellular exosome
0.33	GO:0045202	synapse
0.30	GO:0016021	integral component of membrane

0.34

GO:0016887

sp|O35400|ST2B1_MOUSE
Sulfotransferase family cytosolic 2B member 1
Search

SULT2B1

0.55	Bile salt sulfotransferase

0.60	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.55	GO:0045606	positive regulation of epidermal cell differentiation
0.54	GO:0008202	steroid metabolic process
0.51	GO:0008285	negative regulation of cell proliferation
0.51	GO:1902652	secondary alcohol metabolic process
0.50	GO:0000103	sulfate assimilation
0.44	GO:0006068	ethanol catabolic process
0.43	GO:0051923	sulfation
0.38	GO:0071305	cellular response to vitamin D
0.38	GO:0017085	response to insecticide

0.78	GO:0008146	sulfotransferase activity
0.57	GO:1990239	steroid hormone binding
0.53	GO:0015485	cholesterol binding
0.39	GO:0003676	nucleic acid binding
0.39	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding
0.34	GO:0005515	protein binding
0.33	GO:0008144	drug binding

0.49	GO:0005829	cytosol
0.41	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0070062	extracellular exosome
0.37	GO:0012505	endomembrane system

0.78

GO:0008146

sp|O35403|ST3A1_MOUSE
Amine sulfotransferase
Search

0.54	Amine sulfotransferase

0.40	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.39	GO:0045606	positive regulation of epidermal cell differentiation
0.38	GO:0008203	cholesterol metabolic process
0.38	GO:0008285	negative regulation of cell proliferation
0.37	GO:0000103	sulfate assimilation
0.36	GO:0051923	sulfation
0.34	GO:0006068	ethanol catabolic process

0.77	GO:0008146	sulfotransferase activity
0.39	GO:1990239	steroid hormone binding
0.38	GO:0015485	cholesterol binding
0.33	GO:0003676	nucleic acid binding
0.31	GO:0016787	hydrolase activity

0.36	GO:0005829	cytosol
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0012505	endomembrane system
0.33	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.77

GO:0008146

sp|O35405|PLD3_MOUSE
Phospholipase D3
Search

PLD3

0.92	Phospholipase D family member 3

0.41

GO:0016042

lipid catabolic process

0.45	GO:0004630	phospholipase D activity
0.44	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity
0.34	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0016740	transferase activity

0.41	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.45

EC:3.1.4.4

GO:0004630

sp|O35409|FOLH1_MOUSE
Glutamate carboxypeptidase 2
Search

FOLH1

0.84	Prostate specific membrane antigen variant F

0.54	GO:0035609	C-terminal protein deglutamylation
0.52	GO:0006508	proteolysis
0.46	GO:0006760	folic acid-containing compound metabolic process
0.44	GO:0042135	neurotransmitter catabolic process
0.35	GO:0043065	positive regulation of apoptotic process
0.35	GO:0008652	cellular amino acid biosynthetic process
0.33	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.32	GO:0007186	G-protein coupled receptor signaling pathway

0.61	GO:0004180	carboxypeptidase activity
0.55	GO:1904492	Ac-Asp-Glu binding
0.55	GO:1904493	tetrahydrofolyl-poly(glutamate) polymer binding
0.50	GO:0016805	dipeptidase activity
0.49	GO:0050129	N-formylglutamate deformylase activity
0.46	GO:0008235	metalloexopeptidase activity
0.35	GO:0046872	metal ion binding
0.34	GO:0008239	dipeptidyl-peptidase activity
0.33	GO:0017171	serine hydrolase activity
0.33	GO:0004984	olfactory receptor activity

0.47	GO:0009986	cell surface
0.44	GO:0005887	integral component of plasma membrane
0.37	GO:0070062	extracellular exosome
0.32	GO:0005737	cytoplasm

0.50	EC:3.4.13	GO:0016805
0.49	KEGG:R00525	GO:0050129

sp|O35417|PDYN_MOUSE
Proenkephalin-B
Search

PDYN

0.97	Beta-neoendorphin-dynorphin

0.80	GO:0007218	neuropeptide signaling pathway
0.64	GO:0010469	regulation of receptor activity
0.50	GO:0098916	anterograde trans-synaptic signaling
0.48	GO:0007600	sensory perception
0.38	GO:0046928	regulation of neurotransmitter secretion

0.74	GO:0001515	opioid peptide activity
0.56	GO:0031628	opioid receptor binding
0.52	GO:0005184	neuropeptide hormone activity

0.56	GO:0005576	extracellular region
0.52	GO:0043679	axon terminus
0.51	GO:0043025	neuronal cell body
0.51	GO:0030425	dendrite
0.46	GO:0005886	plasma membrane
0.33	GO:0005737	cytoplasm

sp|O35423|SPYA_MOUSE
Serine--pyruvate aminotransferase, mitochondrial
Search

AGXT

0.84	Serine--pyruvate aminotransferase

0.61	GO:0019265	glycine biosynthetic process, by transamination of glyoxylate
0.60	GO:0046724	oxalic acid secretion
0.60	GO:0019448	L-cysteine catabolic process
0.55	GO:0009436	glyoxylate catabolic process
0.54	GO:0007219	Notch signaling pathway
0.53	GO:0042853	L-alanine catabolic process
0.40	GO:0051591	response to cAMP
0.40	GO:0051384	response to glucocorticoid
0.39	GO:0042866	pyruvate biosynthetic process
0.38	GO:0071391	cellular response to estrogen stimulus

0.79	GO:0004760	serine-pyruvate transaminase activity
0.79	GO:0008453	alanine-glyoxylate transaminase activity
0.57	GO:0043621	protein self-association
0.52	GO:0042803	protein homodimerization activity
0.51	GO:0016597	amino acid binding
0.50	GO:0005102	receptor binding
0.47	GO:0070279	vitamin B6 binding
0.44	GO:0050662	coenzyme binding
0.36	GO:0004038	allantoinase activity
0.36	GO:0050897	cobalt ion binding

0.56	GO:0031907	microbody lumen
0.55	GO:0005777	peroxisome
0.40	GO:0005759	mitochondrial matrix

0.79	EC:2.6.1.51	GO:0004760
0.79	KEGG:R00585	GO:0004760

tr|O35424|O35424_MOUSE
Histocompatibility 2, O region beta locus
Search

0.40	Patr class II histocompatibility antigen, DO beta chain

0.78	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
0.73	GO:0006955	immune response
0.53	GO:0002577	regulation of antigen processing and presentation
0.49	GO:0002683	negative regulation of immune system process
0.45	GO:0048002	antigen processing and presentation of peptide antigen
0.44	GO:0019884	antigen processing and presentation of exogenous antigen
0.41	GO:0019883	antigen processing and presentation of endogenous antigen
0.40	GO:0002377	immunoglobulin production
0.39	GO:0002449	lymphocyte mediated immunity
0.38	GO:0002343	peripheral B cell selection

0.58	GO:0023026	MHC class II protein complex binding
0.41	GO:0042287	MHC protein binding
0.40	GO:0015440	peptide-transporting ATPase activity
0.40	GO:0042605	peptide antigen binding
0.38	GO:1990405	protein antigen binding
0.36	GO:0015643	toxic substance binding
0.36	GO:0032395	MHC class II receptor activity
0.36	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0008134	transcription factor binding
0.35	GO:0032559	adenyl ribonucleotide binding

0.75	GO:0042613	MHC class II protein complex
0.53	GO:0005764	lysosome
0.42	GO:0012505	endomembrane system
0.41	GO:0031410	cytoplasmic vesicle
0.39	GO:0009897	external side of plasma membrane
0.39	GO:0098852	lytic vacuole membrane
0.37	GO:0031984	organelle subcompartment
0.34	GO:0016607	nuclear speck
0.30	GO:0016021	integral component of membrane

0.40

EC:3.6.3.43

GO:0015440

sp|O35425|BOK_MOUSE
Bcl-2-related ovarian killer protein
Search

BOK

0.97	Putative anti-apoptotic bcl-2 family prevent opening of mitochondrial porin channel

0.74	GO:0042981	regulation of apoptotic process
0.60	GO:0051902	negative regulation of mitochondrial depolarization
0.59	GO:1903899	positive regulation of PERK-mediated unfolded protein response
0.59	GO:1901382	regulation of chorionic trophoblast cell proliferation
0.59	GO:0060546	negative regulation of necroptotic process
0.58	GO:0006915	apoptotic process
0.57	GO:0010823	negative regulation of mitochondrion organization
0.56	GO:0070997	neuron death
0.56	GO:0046902	regulation of mitochondrial membrane permeability
0.56	GO:2001056	positive regulation of cysteine-type endopeptidase activity

0.53	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0042803	protein homodimerization activity
0.50	GO:0005102	receptor binding
0.46	GO:0046982	protein heterodimerization activity
0.43	GO:0051400	BH domain binding
0.34	GO:0004197	cysteine-type endopeptidase activity

0.59	GO:0033106	cis-Golgi network membrane
0.56	GO:0032588	trans-Golgi network membrane
0.56	GO:0055038	recycling endosome membrane
0.56	GO:0031901	early endosome membrane
0.50	GO:0005789	endoplasmic reticulum membrane
0.46	GO:0031966	mitochondrial membrane
0.46	GO:0031968	organelle outer membrane
0.45	GO:0019866	organelle inner membrane
0.45	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.34

GO:0004197

sp|O35426|XBP1_MOUSE
X-box-binding protein 1
Search

XBP1

0.92	X-box-binding protein 1

0.59	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
0.57	GO:0060691	epithelial cell maturation involved in salivary gland development
0.56	GO:1900100	positive regulation of plasma cell differentiation
0.56	GO:1903489	positive regulation of lactation
0.56	GO:0001889	liver development
0.56	GO:0035470	positive regulation of vascular wound healing
0.55	GO:1990418	response to insulin-like growth factor stimulus
0.55	GO:2000347	positive regulation of hepatocyte proliferation
0.55	GO:0045348	positive regulation of MHC class II biosynthetic process
0.54	GO:0035356	cellular triglyceride homeostasis

0.61	GO:0003700	DNA binding transcription factor activity
0.52	GO:0001158	enhancer sequence-specific DNA binding
0.51	GO:0001085	RNA polymerase II transcription factor binding
0.51	GO:0001047	core promoter binding
0.47	GO:0046982	protein heterodimerization activity
0.47	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.42	GO:0031490	chromatin DNA binding
0.41	GO:0002020	protease binding
0.40	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding
0.40	GO:0031625	ubiquitin protein ligase binding

0.46	GO:0005783	endoplasmic reticulum
0.44	GO:0005634	nucleus
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.38	GO:0005829	cytosol
0.36	GO:0098793	presynapse
0.34	GO:0070013	intracellular organelle lumen
0.30	GO:0016021	integral component of membrane

sp|O35427|RPC9_MOUSE
DNA-directed RNA polymerase III subunit RPC9
Search

CRCP

0.93	CGRP receptor component

0.71	GO:0006383	transcription by RNA polymerase III
0.65	GO:0007218	neuropeptide signaling pathway
0.48	GO:0006352	DNA-templated transcription, initiation
0.40	GO:0061484	hematopoietic stem cell homeostasis

0.75	GO:0001635	calcitonin gene-related peptide receptor activity
0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.53	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding

0.68	GO:0001669	acrosomal vesicle
0.64	GO:0061695	transferase complex, transferring phosphorus-containing groups
0.49	GO:0044451	nucleoplasm part
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0003899

sp|O35435|PYRD_MOUSE
Dihydroorotate dehydrogenase (quinone), mitochondrial
Search

DHODH

0.50	Dihydroorotate dehydrogenase (quinone), mitochondrial

0.72	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process
0.70	GO:0006222	UMP biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.40	GO:1903576	response to L-arginine
0.39	GO:0031000	response to caffeine
0.39	GO:0007595	lactation
0.39	GO:0090140	regulation of mitochondrial fission
0.39	GO:0007565	female pregnancy
0.38	GO:0043065	positive regulation of apoptotic process
0.37	GO:0042594	response to starvation

0.77	GO:0004152	dihydroorotate dehydrogenase activity
0.39	GO:0048039	ubiquinone binding
0.36	GO:0010181	FMN binding
0.36	GO:0004252	serine-type endopeptidase activity
0.34	GO:0008144	drug binding

0.59	GO:0031966	mitochondrial membrane
0.59	GO:0019866	organelle inner membrane
0.47	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.38	GO:0043025	neuronal cell body
0.30	GO:0031224	intrinsic component of membrane

0.77	EC:1.3.5.2	GO:0004152
0.77	KEGG:R01868	GO:0004152

sp|O35437|TCF21_MOUSE
Transcription factor 21
Search

TCF21

0.97	LOW QUALITY PROTEIN: transcription factor 21

0.68	GO:0014707	branchiomeric skeletal muscle development
0.66	GO:0060539	diaphragm development
0.63	GO:0060021	palate development
0.63	GO:0072277	metanephric glomerular capillary formation
0.63	GO:0060435	bronchiole development
0.63	GO:0072162	metanephric mesenchymal cell differentiation
0.62	GO:0060426	lung vasculature development
0.61	GO:0060766	negative regulation of androgen receptor signaling pathway
0.60	GO:0048286	lung alveolus development
0.60	GO:0001658	branching involved in ureteric bud morphogenesis

0.68	GO:0046983	protein dimerization activity
0.62	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.60	GO:0070888	E-box binding
0.59	GO:0043425	bHLH transcription factor binding
0.59	GO:0050681	androgen receptor binding
0.57	GO:0042826	histone deacetylase binding
0.57	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.47	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.34	GO:0003714	transcription corepressor activity

0.49	GO:0005634	nucleus
0.42	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part

sp|O35445|RNF5_MOUSE
E3 ubiquitin-protein ligase RNF5
Search

RNF5

0.51	Ring finger protein 5

0.60	GO:0071712	ER-associated misfolded protein catabolic process
0.55	GO:2000785	regulation of autophagosome assembly
0.54	GO:0031648	protein destabilization
0.54	GO:0070534	protein K63-linked ubiquitination
0.54	GO:0070936	protein K48-linked ubiquitination
0.53	GO:0030433	ubiquitin-dependent ERAD pathway
0.51	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.50	GO:0009617	response to bacterium
0.49	GO:0010507	negative regulation of autophagy
0.45	GO:0051865	protein autoubiquitination

0.56	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway
0.55	GO:0044390	ubiquitin-like protein conjugating enzyme binding
0.50	GO:0016874	ligase activity
0.49	GO:0042802	identical protein binding
0.36	GO:0046872	metal ion binding
0.34	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity

0.62	GO:0036513	Derlin-1 retrotranslocation complex
0.38	GO:0005741	mitochondrial outer membrane
0.37	GO:0044322	endoplasmic reticulum quality control compartment
0.34	GO:0043198	dendritic shaft
0.34	GO:0030426	growth cone
0.34	GO:0001726	ruffle
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.50

GO:0016874

sp|O35448|PPT2_MOUSE
Lysosomal thioesterase PPT2
Search

PPT2

0.93	Palmitoyl-protein thioesterase 2

0.85	GO:0098734	macromolecule depalmitoylation
0.35	GO:0046949	fatty-acyl-CoA biosynthetic process

0.85	GO:0008474	palmitoyl-(protein) hydrolase activity
0.34	GO:0005509	calcium ion binding

0.39	GO:0005764	lysosome
0.37	GO:0070062	extracellular exosome
0.35	GO:0005775	vacuolar lumen
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:3.1.2.22

GO:0008474

sp|O35449|PRRT1_MOUSE
Proline-rich transmembrane protein 1
Search

PRRT1

0.97	LOW QUALITY PROTEIN: proline-rich transmembrane protein 1

0.68	GO:0009607	response to biotic stimulus
0.34	GO:0006099	tricarboxylic acid cycle
0.33	GO:0030218	erythrocyte differentiation
0.32	GO:0035335	peptidyl-tyrosine dephosphorylation
0.32	GO:0006457	protein folding
0.32	GO:0050821	protein stabilization
0.32	GO:0006413	translational initiation
0.32	GO:0019310	inositol catabolic process
0.32	GO:0006950	response to stress
0.32	GO:0006259	DNA metabolic process

0.35	GO:0016751	S-succinyltransferase activity
0.33	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0030492	hemoglobin binding
0.32	GO:0047590	5-dehydro-2-deoxygluconokinase activity
0.32	GO:0003743	translation initiation factor activity
0.32	GO:0008880	glucuronate isomerase activity
0.32	GO:0016791	phosphatase activity
0.32	GO:0003887	DNA-directed DNA polymerase activity
0.32	GO:0003774	motor activity
0.32	GO:0051082	unfolded protein binding

0.41	GO:0045202	synapse
0.40	GO:0030054	cell junction
0.36	GO:0005886	plasma membrane
0.35	GO:0045252	oxoglutarate dehydrogenase complex
0.33	GO:0061695	transferase complex, transferring phosphorus-containing groups
0.33	GO:0090575	RNA polymerase II transcription factor complex
0.32	GO:0044451	nucleoplasm part
0.32	GO:0009425	bacterial-type flagellum basal body
0.30	GO:0016021	integral component of membrane

0.35

EC:2.3.1

GO:0016751

sp|O35450|FKBPL_MOUSE
FK506-binding protein-like
Search

FKBPL

0.91	Peptidyl-prolyl cis-trans isomerase FKBP5

0.85	GO:1905553	regulation of blood vessel branching
0.45	GO:0032781	positive regulation of ATPase activity
0.40	GO:0000413	protein peptidyl-prolyl isomerization
0.39	GO:0050821	protein stabilization
0.39	GO:0009314	response to radiation
0.37	GO:0000395	mRNA 5'-splice site recognition
0.36	GO:0000387	spliceosomal snRNP assembly
0.35	GO:0006457	protein folding
0.34	GO:0006470	protein dephosphorylation

0.45	GO:0001671	ATPase activator activity
0.44	GO:0051087	chaperone binding
0.43	GO:0016853	isomerase activity
0.37	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0030619	U1 snRNA binding
0.35	GO:0003729	mRNA binding
0.34	GO:0008270	zinc ion binding
0.34	GO:0016791	phosphatase activity

0.61	GO:0005576	extracellular region
0.37	GO:0005829	cytosol
0.36	GO:0000243	commitment complex
0.36	GO:0071004	U2-type prespliceosome
0.36	GO:0005685	U1 snRNP
0.30	GO:0016020	membrane

0.43

EC:5

GO:0016853

sp|O35451|ATF6B_MOUSE
Cyclic AMP-dependent transcription factor ATF-6 beta
Search

ATF6B

0.95	Cyclic AMP-dependent transcription factor ATF-6 beta

0.84	GO:0030968	endoplasmic reticulum unfolded protein response
0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0043620	regulation of DNA-templated transcription in response to stress
0.56	GO:0045893	positive regulation of transcription, DNA-templated
0.38	GO:0001654	eye development
0.38	GO:0043065	positive regulation of apoptotic process
0.38	GO:0007601	visual perception
0.36	GO:0045014	negative regulation of transcription by glucose
0.36	GO:0006984	ER-nucleus signaling pathway
0.36	GO:0007076	mitotic chromosome condensation

0.85	GO:0035497	cAMP response element binding
0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.38	GO:0046982	protein heterodimerization activity
0.37	GO:0042802	identical protein binding
0.33	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0003713	transcription coactivator activity

0.67	GO:0012505	endomembrane system
0.61	GO:0005634	nucleus
0.53	GO:0031984	organelle subcompartment
0.52	GO:0005667	transcription factor complex
0.51	GO:0032993	protein-DNA complex
0.48	GO:0043233	organelle lumen
0.45	GO:0044444	cytoplasmic part
0.44	GO:0043232	intracellular non-membrane-bounded organelle
0.38	GO:0005615	extracellular space
0.35	GO:0097708	intracellular vesicle

tr|O35452|O35452_MOUSE
Tenascin X
Search

TNXB

0.62	Tenascin XB

0.85	GO:0030199	collagen fibril organization
0.58	GO:0043506	regulation of JUN kinase activity
0.56	GO:0007160	cell-matrix adhesion
0.56	GO:0006641	triglyceride metabolic process
0.54	GO:0098609	cell-cell adhesion
0.50	GO:0006631	fatty acid metabolic process
0.46	GO:0048251	elastic fiber assembly
0.46	GO:0032963	collagen metabolic process
0.42	GO:0030036	actin cytoskeleton organization
0.36	GO:0042127	regulation of cell proliferation

0.60	GO:0008201	heparin binding
0.57	GO:0005518	collagen binding
0.45	GO:0005178	integrin binding
0.33	GO:0090729	toxin activity
0.32	GO:0045545	syndecan binding

0.75	GO:0005578	proteinaceous extracellular matrix
0.53	GO:0005615	extracellular space
0.44	GO:0044420	extracellular matrix component
0.43	GO:0005581	collagen trimer
0.42	GO:0099512	supramolecular fiber
0.39	GO:1903561	extracellular vesicle
0.34	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|O35453|HEPS_MOUSE
Serine protease hepsin
Search

HPN

0.94	Truncated hepsin serine protease

0.61	GO:2000347	positive regulation of hepatocyte proliferation
0.61	GO:0034769	basement membrane disassembly
0.61	GO:0010756	positive regulation of plasminogen activation
0.61	GO:0006508	proteolysis
0.60	GO:0043923	positive regulation by host of viral transcription
0.59	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.57	GO:0050680	negative regulation of epithelial cell proliferation
0.57	GO:0030307	positive regulation of cell growth
0.54	GO:0043066	negative regulation of apoptotic process
0.53	GO:0097195	pilomotor reflex

0.69	GO:0004252	serine-type endopeptidase activity
0.68	GO:0070008	serine-type exopeptidase activity
0.53	GO:0005044	scavenger receptor activity
0.49	GO:0015269	calcium-activated potassium channel activity
0.34	GO:0016758	transferase activity, transferring hexosyl groups
0.34	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding
0.33	GO:0005242	inward rectifier potassium channel activity
0.33	GO:0017080	sodium channel regulator activity
0.31	GO:0016491	oxidoreductase activity

0.55	GO:0031965	nuclear membrane
0.53	GO:0009986	cell surface
0.51	GO:0005789	endoplasmic reticulum membrane
0.48	GO:0005887	integral component of plasma membrane
0.48	GO:0043025	neuronal cell body
0.46	GO:0005911	cell-cell junction
0.39	GO:0016324	apical plasma membrane
0.37	GO:0070062	extracellular exosome
0.33	GO:0046658	anchored component of plasma membrane
0.33	GO:0019897	extrinsic component of plasma membrane

0.69

GO:0004252

sp|O35454|CLCN6_MOUSE
Chloride transport protein 6
Search

CLCN6

0.52	Chloride voltage-gated channel 6

0.76	GO:1902476	chloride transmembrane transport
0.39	GO:0009612	response to mechanical stimulus
0.35	GO:0006884	cell volume homeostasis
0.33	GO:0007165	signal transduction

0.77	GO:0005247	voltage-gated chloride channel activity
0.36	GO:0015297	antiporter activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0010008	endosome membrane
0.37	GO:0005765	lysosomal membrane
0.30	GO:0016021	integral component of membrane

sp|O35457|CCRL2_MOUSE
C-C chemokine receptor-like 2
Search

CCRL2

0.97	C-C motif chemokine receptor like 2

0.84	GO:0070098	chemokine-mediated signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.71	GO:0006935	chemotaxis
0.56	GO:0006954	inflammatory response
0.43	GO:0090026	positive regulation of monocyte chemotaxis
0.43	GO:0006955	immune response
0.39	GO:0001974	blood vessel remodeling
0.39	GO:0006874	cellular calcium ion homeostasis
0.38	GO:0051094	positive regulation of developmental process
0.37	GO:0051240	positive regulation of multicellular organismal process

0.84	GO:0004950	chemokine receptor activity
0.63	GO:0048020	CCR chemokine receptor binding
0.40	GO:0019957	C-C chemokine binding
0.35	GO:0004435	phosphatidylinositol phospholipase C activity
0.34	GO:0042803	protein homodimerization activity

0.51	GO:0005887	integral component of plasma membrane
0.37	GO:0009897	external side of plasma membrane
0.35	GO:0043204	perikaryon
0.35	GO:0030425	dendrite
0.35	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005829	cytosol

0.35	EC:3.1.4.11	GO:0004435
0.35	KEGG:R03435	GO:0004435

sp|O35459|ECH1_MOUSE
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
Search

ECH1

0.85	Peroxisomal enoyl coenzyme A hydratase 1

0.39	GO:0006635	fatty acid beta-oxidation
0.35	GO:0006397	mRNA processing
0.34	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.33	GO:0015031	protein transport

0.53	GO:0016853	isomerase activity
0.45	GO:0005102	receptor binding
0.34	GO:0003723	RNA binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005739	mitochondrion
0.38	GO:0005777	peroxisome
0.37	GO:0070062	extracellular exosome
0.35	GO:0019013	viral nucleocapsid
0.34	GO:0005634	nucleus
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0030126	COPI vesicle coat

0.53

EC:5

GO:0016853

sp|O35464|SEM6A_MOUSE
Semaphorin-6A
Search

SEMA6A

0.88	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (Semaphorin) 6A

0.54	GO:2001224	positive regulation of neuron migration
0.50	GO:0051642	centrosome localization
0.49	GO:0001764	neuron migration
0.48	GO:0071526	semaphorin-plexin signaling pathway
0.48	GO:0007411	axon guidance
0.39	GO:0003403	optic vesicle formation
0.37	GO:1903671	negative regulation of sprouting angiogenesis
0.30	GO:0008219	cell death

0.51	GO:0030215	semaphorin receptor binding
0.44	GO:0004888	transmembrane signaling receptor activity
0.36	GO:0042802	identical protein binding

0.45	GO:0005887	integral component of plasma membrane
0.30	GO:0043005	neuron projection

sp|O35465|FKBP8_MOUSE
Peptidyl-prolyl cis-trans isomerase FKBP8
Search

FKBP8

0.47	Peptidyl-prolyl cis-trans isomerase FKBP8

0.81	GO:0021904	dorsal/ventral neural tube patterning
0.78	GO:0030513	positive regulation of BMP signaling pathway
0.77	GO:0035264	multicellular organism growth
0.76	GO:0001708	cell fate specification
0.76	GO:0007224	smoothened signaling pathway
0.74	GO:0043010	camera-type eye development
0.71	GO:0061077	chaperone-mediated protein folding
0.71	GO:0043066	negative regulation of apoptotic process
0.71	GO:0006915	apoptotic process
0.68	GO:0001933	negative regulation of protein phosphorylation

0.79	GO:0097718	disordered domain specific binding
0.78	GO:0005528	FK506 binding
0.67	GO:0042802	identical protein binding
0.66	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.42	GO:0046872	metal ion binding

0.70	GO:0030176	integral component of endoplasmic reticulum membrane
0.65	GO:0005829	cytosol
0.58	GO:0005739	mitochondrion
0.57	GO:0031967	organelle envelope
0.57	GO:0031090	organelle membrane
0.55	GO:0043234	protein complex

0.66

EC:5.2.1.8

GO:0003755

sp|O35468|WNT9B_MOUSE
Protein Wnt-9b
Search

sp|O35469|3BHS6_MOUSE
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 6
Search

0.50	3 beta-hydroxysteroid dehydrogenase isomerase VI

0.78	GO:0006694	steroid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.40	GO:0034754	cellular hormone metabolic process
0.39	GO:0042446	hormone biosynthetic process
0.38	GO:0014070	response to organic cyclic compound
0.38	GO:0010288	response to lead ion
0.38	GO:0033327	Leydig cell differentiation
0.38	GO:0034698	response to gonadotropin
0.37	GO:0021766	hippocampus development
0.37	GO:0008211	glucocorticoid metabolic process

0.83	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
0.54	GO:0102294	cholesterol dehydrogenase activity
0.54	GO:0004769	steroid delta-isomerase activity
0.38	GO:0010181	FMN binding
0.37	GO:0005496	steroid binding
0.36	GO:0035410	dihydrotestosterone 17-beta-dehydrogenase activity
0.36	GO:0030283	testosterone dehydrogenase [NAD(P)] activity
0.35	GO:0051287	NAD binding
0.35	GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity
0.33	GO:0016651	oxidoreductase activity, acting on NAD(P)H

0.46	GO:0005789	endoplasmic reticulum membrane
0.44	GO:0005758	mitochondrial intermembrane space
0.44	GO:0031966	mitochondrial membrane
0.41	GO:0019866	organelle inner membrane
0.39	GO:0097425	smooth endoplasmic reticulum part
0.36	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

0.83

EC:1.1.1.145

GO:0003854

sp|O35473|C1D_MOUSE
Nuclear nucleic acid-binding protein C1D
Search

C1D

0.95	Putative dna-binding protein c1d involved in regulation of double-strand break repair

0.77	GO:0000460	maturation of 5.8S rRNA
0.63	GO:0045892	negative regulation of transcription, DNA-templated
0.50	GO:0006915	apoptotic process
0.42	GO:0006351	transcription, DNA-templated

0.77	GO:0016922	ligand-dependent nuclear receptor binding
0.71	GO:0003714	transcription corepressor activity
0.57	GO:0003723	RNA binding
0.52	GO:0003677	DNA binding

0.71	GO:0017053	transcriptional repressor complex
0.70	GO:0005730	nucleolus
0.64	GO:0000178	exosome (RNase complex)
0.39	GO:0005737	cytoplasm
0.38	GO:0005654	nucleoplasm

sp|O35474|EDIL3_MOUSE
EGF-like repeat and discoidin I-like domain-containing protein 3
Search

EDIL3

0.96	EGF like repeats and discoidin domains 3

0.53	GO:0010811	positive regulation of cell-substrate adhesion
0.37	GO:0007155	cell adhesion
0.36	GO:0007275	multicellular organism development

0.84	GO:0005178	integrin binding
0.68	GO:0005509	calcium ion binding

0.51	GO:0031012	extracellular matrix
0.38	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|O35484|AZIN1_MOUSE
Antizyme inhibitor 1
Search

AZIN1

0.97	Antizyme inhibitor 1

0.69	GO:0006596	polyamine biosynthetic process
0.67	GO:0043085	positive regulation of catalytic activity
0.54	GO:1902269	positive regulation of polyamine transmembrane transport
0.50	GO:0042177	negative regulation of protein catabolic process
0.45	GO:0009445	putrescine metabolic process
0.43	GO:0006591	ornithine metabolic process
0.35	GO:0006521	regulation of cellular amino acid metabolic process

0.83	GO:0042978	ornithine decarboxylase activator activity
0.44	GO:0004586	ornithine decarboxylase activity
0.33	GO:0005515	protein binding

0.43	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm

0.44	EC:4.1.1.17	GO:0004586
0.44	KEGG:R00670	GO:0004586

sp|O35486|CRBS_MOUSE
Beta-crystallin S
Search

CRYGS

0.95	Crystallin gamma S

0.78	GO:0002088	lens development in camera-type eye
0.70	GO:0002009	morphogenesis of an epithelium
0.50	GO:0007601	visual perception
0.42	GO:0030855	epithelial cell differentiation
0.40	GO:0034614	cellular response to reactive oxygen species
0.36	GO:0048593	camera-type eye morphogenesis
0.36	GO:0000904	cell morphogenesis involved in differentiation

0.84	GO:0005212	structural constituent of eye lens
0.36	GO:0005515	protein binding

0.43	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm

sp|O35488|S27A2_MOUSE
Very long-chain acyl-CoA synthetase
Search

SLC27A2

0.88	Very long-chain acyl-CoA synthetase

0.73	GO:0015908	fatty acid transport
0.72	GO:0001676	long-chain fatty acid metabolic process
0.66	GO:0006699	bile acid biosynthetic process
0.60	GO:0097089	methyl-branched fatty acid metabolic process
0.59	GO:0001561	fatty acid alpha-oxidation
0.56	GO:0042760	very long-chain fatty acid catabolic process
0.52	GO:0006635	fatty acid beta-oxidation
0.35	GO:0043312	neutrophil degranulation

0.78	GO:0031957	very long-chain fatty acid-CoA ligase activity
0.72	GO:0004467	long-chain fatty acid-CoA ligase activity
0.64	GO:0015245	fatty acid transmembrane transporter activity
0.61	GO:0070251	pristanate-CoA ligase activity
0.61	GO:0050197	phytanate-CoA ligase activity
0.50	GO:0005102	receptor binding
0.49	GO:0019899	enzyme binding
0.38	GO:0102391	decanoate--CoA ligase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding

0.55	GO:0005788	endoplasmic reticulum lumen
0.54	GO:0005779	integral component of peroxisomal membrane
0.52	GO:0030176	integral component of endoplasmic reticulum membrane
0.44	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.36	GO:0035579	specific granule membrane
0.33	GO:0005886	plasma membrane

0.72	EC:6.2.1.3	GO:0004467
0.61	KEGG:R03631	GO:0050197

sp|O35490|BHMT1_MOUSE
Betaine--homocysteine S-methyltransferase 1
Search

BHMT

0.95	Betaine--homocysteine S-methyltransferase

0.72	GO:0009086	methionine biosynthetic process
0.63	GO:0032259	methylation
0.52	GO:0006577	amino-acid betaine metabolic process
0.51	GO:0043102	amino acid salvage
0.43	GO:0017144	drug metabolic process
0.40	GO:0033477	S-methylmethionine metabolic process
0.39	GO:0044270	cellular nitrogen compound catabolic process
0.38	GO:1901565	organonitrogen compound catabolic process
0.36	GO:0006732	coenzyme metabolic process
0.36	GO:0050666	regulation of homocysteine metabolic process

0.82	GO:0047150	betaine-homocysteine S-methyltransferase activity
0.63	GO:0008270	zinc ion binding
0.40	GO:0061627	S-methylmethionine-homocysteine S-methyltransferase activity
0.34	GO:0032403	protein complex binding

0.52	GO:0070062	extracellular exosome
0.49	GO:0005737	cytoplasm
0.33	GO:0043234	protein complex

0.82	EC:2.1.1.5	GO:0047150
0.82	KEGG:R02821	GO:0047150

sp|O35491|CLK2_MOUSE
Dual specificity protein kinase CLK2
Search

CLK2

0.64	Dual specificity protein kinase CLK2

0.63	GO:0006468	protein phosphorylation
0.53	GO:0032526	response to retinoic acid
0.53	GO:0010212	response to ionizing radiation
0.53	GO:0045721	negative regulation of gluconeogenesis
0.53	GO:0043484	regulation of RNA splicing
0.49	GO:0018212	peptidyl-tyrosine modification
0.38	GO:0015031	protein transport
0.36	GO:0006836	neurotransmitter transport

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0042802	identical protein binding
0.37	GO:0019905	syntaxin binding
0.34	GO:0031625	ubiquitin protein ligase binding

0.51	GO:0016604	nuclear body
0.35	GO:0070062	extracellular exosome
0.34	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

sp|O35492|CLK3_MOUSE
Dual specificity protein kinase CLK3
Search

CLK3

0.96	Dual specificity protein kinase CLK3

0.63	GO:0006468	protein phosphorylation
0.46	GO:0043484	regulation of RNA splicing
0.44	GO:0018212	peptidyl-tyrosine modification

0.64	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0004713	protein tyrosine kinase activity
0.43	GO:0042802	identical protein binding
0.43	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.35	GO:0003723	RNA binding

0.46	GO:0045111	intermediate filament cytoskeleton
0.44	GO:0001669	acrosomal vesicle
0.44	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.64

GO:0004674

sp|O35493|CLK4_MOUSE
Dual specificity protein kinase CLK4
Search

CLK4

0.88	Dual specificity protein kinase CLK4

0.63	GO:0006468	protein phosphorylation
0.43	GO:0043484	regulation of RNA splicing
0.41	GO:0018212	peptidyl-tyrosine modification
0.40	GO:0018210	peptidyl-threonine modification
0.40	GO:0018209	peptidyl-serine modification
0.36	GO:0008283	cell proliferation
0.35	GO:0000413	protein peptidyl-prolyl isomerization
0.34	GO:0006457	protein folding
0.34	GO:0007264	small GTPase mediated signal transduction
0.33	GO:0065009	regulation of molecular function

0.66	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0004713	protein tyrosine kinase activity
0.42	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.37	GO:0005515	protein binding
0.35	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.34	GO:0098772	molecular function regulator

0.38	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm

0.66

GO:0004674

sp|O35495|CDK14_MOUSE
Cyclin-dependent kinase 14
Search

CDK14

0.96	Serine/threonine-protein kinase PFTAIRE-1 (Predicted)

0.60	GO:0006468	protein phosphorylation
0.55	GO:0000086	G2/M transition of mitotic cell cycle
0.53	GO:0060828	regulation of canonical Wnt signaling pathway
0.50	GO:0051726	regulation of cell cycle
0.42	GO:0016055	Wnt signaling pathway
0.40	GO:0051301	cell division

0.65	GO:0004674	protein serine/threonine kinase activity
0.56	GO:0097472	cyclin-dependent protein kinase activity
0.53	GO:0030332	cyclin binding
0.52	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0020037	heme binding

0.59	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex
0.47	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.42	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.65

GO:0004674

sp|O35516|NOTC2_MOUSE
Neurogenic locus notch homolog protein 2
Search

0.84	Notch homolog 2

0.81	GO:0007219	Notch signaling pathway
0.70	GO:0030154	cell differentiation
0.68	GO:0007275	multicellular organism development
0.66	GO:0050793	regulation of developmental process
0.55	GO:0006355	regulation of transcription, DNA-templated
0.51	GO:0045967	negative regulation of growth rate
0.50	GO:0009653	anatomical structure morphogenesis
0.49	GO:0060324	face development
0.48	GO:0046849	bone remodeling
0.48	GO:0042246	tissue regeneration

0.68	GO:0005509	calcium ion binding
0.62	GO:0060089	molecular transducer activity
0.36	GO:0045296	cadherin binding
0.35	GO:0042802	identical protein binding
0.35	GO:0019899	enzyme binding
0.34	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.33	GO:0004871	signal transducer activity
0.33	GO:0051059	NF-kappaB binding

0.47	GO:0043235	receptor complex
0.45	GO:0009986	cell surface
0.44	GO:0005654	nucleoplasm
0.42	GO:0005887	integral component of plasma membrane
0.35	GO:0015629	actin cytoskeleton
0.35	GO:0005829	cytosol
0.34	GO:0000139	Golgi membrane
0.34	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005576	extracellular region
0.32	GO:0005929	cilium

sp|O35526|STX1A_MOUSE
Syntaxin-1A
Search

STX1A

0.74	Syntaxin-1A isoform A

0.78	GO:0017157	regulation of exocytosis
0.69	GO:0016192	vesicle-mediated transport
0.68	GO:0006886	intracellular protein transport
0.68	GO:0061025	membrane fusion
0.62	GO:0001956	positive regulation of neurotransmitter secretion
0.61	GO:2000463	positive regulation of excitatory postsynaptic potential
0.61	GO:1902803	regulation of synaptic vesicle transport
0.60	GO:0098693	regulation of synaptic vesicle cycle
0.55	GO:0097480	establishment of synaptic vesicle localization
0.55	GO:0099504	synaptic vesicle cycle

0.80	GO:0005484	SNAP receptor activity
0.76	GO:0000149	SNARE binding
0.55	GO:0019900	kinase binding
0.54	GO:0019869	chloride channel inhibitor activity
0.53	GO:0019855	calcium channel inhibitor activity
0.46	GO:0017022	myosin binding
0.45	GO:0005102	receptor binding
0.41	GO:0043008	ATP-dependent protein binding
0.40	GO:0019904	protein domain specific binding
0.40	GO:0048306	calcium-dependent protein binding

0.57	GO:0098793	presynapse
0.56	GO:0031201	SNARE complex
0.56	GO:0030424	axon
0.55	GO:0070382	exocytic vesicle
0.50	GO:0030658	transport vesicle membrane
0.49	GO:0031965	nuclear membrane
0.45	GO:0005887	integral component of plasma membrane
0.41	GO:0097060	synaptic membrane
0.40	GO:0034705	potassium channel complex
0.40	GO:0042641	actomyosin

sp|O35536|TFPI2_MOUSE
Tissue factor pathway inhibitor 2
Search

TFPI2

0.75	Tissue factor pathway inhibitor

0.76	GO:0010951	negative regulation of endopeptidase activity
0.73	GO:0007596	blood coagulation
0.51	GO:0071498	cellular response to fluid shear stress
0.40	GO:0006508	proteolysis
0.36	GO:0006030	chitin metabolic process
0.36	GO:0030198	extracellular matrix organization
0.34	GO:0030195	negative regulation of blood coagulation
0.34	GO:0071383	cellular response to steroid hormone stimulus

0.79	GO:0004867	serine-type endopeptidase inhibitor activity
0.40	GO:0008233	peptidase activity
0.39	GO:0005201	extracellular matrix structural constituent
0.36	GO:0008061	chitin binding

0.64	GO:0005576	extracellular region
0.34	GO:0005901	caveola
0.33	GO:0009986	cell surface
0.30	GO:0031224	intrinsic component of membrane

0.40

GO:0008233

sp|O35544|EAA4_MOUSE
Excitatory amino acid transporter 4
Search

SLC1A6

0.45	Amino acid transporter

0.56	GO:0089711	L-glutamate transmembrane transport
0.50	GO:0042391	regulation of membrane potential
0.50	GO:0089718	amino acid import across plasma membrane
0.50	GO:1903802	L-glutamate(1-) import across plasma membrane
0.49	GO:0001504	neurotransmitter uptake
0.48	GO:0089712	L-aspartate transmembrane transport
0.48	GO:0070779	D-aspartate import
0.47	GO:0009449	gamma-aminobutyric acid biosynthetic process
0.46	GO:0031223	auditory behavior
0.45	GO:0021545	cranial nerve development

0.72	GO:0015293	symporter activity
0.57	GO:0005313	L-glutamate transmembrane transporter activity
0.47	GO:0016595	glutamate binding
0.44	GO:0015081	sodium ion transmembrane transporter activity
0.41	GO:0022853	active ion transmembrane transporter activity
0.35	GO:0015183	L-aspartate transmembrane transporter activity
0.35	GO:0046872	metal ion binding

0.51	GO:0045111	intermediate filament cytoskeleton
0.47	GO:0005794	Golgi apparatus
0.44	GO:0043025	neuronal cell body
0.43	GO:0043005	neuron projection
0.42	GO:0009986	cell surface
0.42	GO:0005887	integral component of plasma membrane
0.34	GO:0016323	basolateral plasma membrane
0.34	GO:0098794	postsynapse
0.34	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0019866	organelle inner membrane

sp|O35551|RABE1_MOUSE
Rab GTPase-binding effector protein 1
Search

RABEP1

0.78	Rab GTPase-binding effector protein 1

0.76	GO:0043547	positive regulation of GTPase activity
0.75	GO:0010469	regulation of receptor activity
0.71	GO:0006897	endocytosis
0.45	GO:0060271	cilium assembly
0.33	GO:0006915	apoptotic process
0.33	GO:0015031	protein transport
0.32	GO:0010976	positive regulation of neuron projection development
0.32	GO:0061025	membrane fusion

0.78	GO:0008083	growth factor activity
0.76	GO:0005096	GTPase activator activity
0.41	GO:0019904	protein domain specific binding
0.41	GO:0042803	protein homodimerization activity

0.76	GO:0005768	endosome
0.42	GO:0030139	endocytic vesicle
0.37	GO:0043234	protein complex
0.36	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0044433	cytoplasmic vesicle part
0.32	GO:0005615	extracellular space
0.32	GO:0098805	whole membrane
0.32	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

sp|O35565|FGF10_MOUSE
Fibroblast growth factor 10
Search

FGF10

0.62	Fibroblast growth factor

0.84	GO:0008543	fibroblast growth factor receptor signaling pathway
0.75	GO:0010469	regulation of receptor activity
0.64	GO:0050674	urothelial cell proliferation
0.63	GO:0050675	regulation of urothelial cell proliferation
0.62	GO:0070075	tear secretion
0.62	GO:0071338	positive regulation of hair follicle cell proliferation
0.62	GO:0060447	bud outgrowth involved in lung branching
0.62	GO:0031659	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
0.62	GO:0051549	positive regulation of keratinocyte migration
0.62	GO:0061033	secretion by lung epithelial cell involved in lung growth

0.85	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.61	GO:0042056	chemoattractant activity
0.56	GO:0008201	heparin binding
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0004713	protein tyrosine kinase activity

0.66	GO:0005576	extracellular region
0.56	GO:0009986	cell surface
0.48	GO:0005634	nucleus
0.43	GO:0005886	plasma membrane
0.40	GO:0005794	Golgi apparatus
0.39	GO:0070013	intracellular organelle lumen
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|O35566|CD151_MOUSE
CD151 antigen
Search

CD151

0.60	Tetraspanin

0.52	GO:0042098	T cell proliferation
0.48	GO:0016477	cell migration
0.41	GO:0007166	cell surface receptor signaling pathway

0.51	GO:0005178	integrin binding
0.37	GO:0005509	calcium ion binding

0.50	GO:0005604	basement membrane
0.40	GO:0005887	integral component of plasma membrane

sp|O35593|PSDE_MOUSE
26S proteasome non-ATPase regulatory subunit 14
Search

PSMD14

0.90	Testis tissue sperm-binding protein Li 69n

0.85	GO:0070536	protein K63-linked deubiquitination
0.52	GO:0010950	positive regulation of endopeptidase activity
0.50	GO:0006303	double-strand break repair via nonhomologous end joining
0.50	GO:0061136	regulation of proteasomal protein catabolic process
0.49	GO:0000724	double-strand break repair via homologous recombination
0.46	GO:0001878	response to yeast
0.38	GO:0045471	response to ethanol
0.38	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

0.85	GO:0061578	Lys63-specific deubiquitinase activity
0.54	GO:0061133	endopeptidase activator activity
0.52	GO:0070628	proteasome binding
0.49	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.34	GO:0008237	metallopeptidase activity
0.34	GO:0003984	acetolactate synthase activity
0.33	GO:0004175	endopeptidase activity
0.33	GO:0046872	metal ion binding

0.66	GO:1905369	endopeptidase complex
0.55	GO:0043234	protein complex
0.43	GO:0005622	intracellular
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.33	GO:0012505	endomembrane system

0.49

EC:3.4.19.12

GO:0036459

sp|O35594|IFT81_MOUSE
Intraflagellar transport protein 81 homolog
Search

IFT81

0.96	Intraflagellar transport protein 81

0.81	GO:0042073	intraciliary transport
0.77	GO:0060271	cilium assembly
0.55	GO:0007283	spermatogenesis
0.45	GO:0048793	pronephros development
0.43	GO:0032006	regulation of TOR signaling
0.34	GO:0030154	cell differentiation

0.72

GO:0015631

tubulin binding

0.82	GO:0030992	intraciliary transport particle B
0.74	GO:0005929	cilium
0.56	GO:0097223	sperm part
0.55	GO:0005813	centrosome
0.53	GO:0120038	plasma membrane bounded cell projection part

sp|O35595|PTC2_MOUSE
Protein patched homolog 2
Search

PTCH2

0.91

Patched

0.66	GO:0009957	epidermal cell fate specification
0.64	GO:0045606	positive regulation of epidermal cell differentiation
0.62	GO:0001709	cell fate determination
0.60	GO:0007165	signal transduction
0.56	GO:0042633	hair cycle
0.56	GO:0048513	animal organ development
0.51	GO:0021997	neural plate axis specification
0.51	GO:0010157	response to chlorate
0.51	GO:0045879	negative regulation of smoothened signaling pathway
0.51	GO:0071397	cellular response to cholesterol

0.86	GO:0008158	hedgehog receptor activity
0.67	GO:0005119	smoothened binding
0.67	GO:0097108	hedgehog family protein binding
0.50	GO:0005113	patched binding
0.48	GO:0015485	cholesterol binding
0.48	GO:0030332	cyclin binding
0.47	GO:0008201	heparin binding
0.45	GO:0032403	protein complex binding
0.34	GO:0016779	nucleotidyltransferase activity
0.33	GO:0008270	zinc ion binding

0.48	GO:0005901	caveola
0.47	GO:0030496	midbody
0.46	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0005929	cilium
0.44	GO:0005794	Golgi apparatus
0.39	GO:0044294	dendritic growth cone
0.38	GO:0044295	axonal growth cone
0.37	GO:0014069	postsynaptic density
0.35	GO:0005634	nucleus
0.34	GO:0030666	endocytic vesicle membrane

0.34

EC:2.7.7

GO:0016779

sp|O35598|ADA10_MOUSE
Disintegrin and metalloproteinase domain-containing protein 10
Search

ADAM10

0.92	Disintegrin and metalloproteinase domain-containing protein 10

0.85	GO:0006509	membrane protein ectodomain proteolysis
0.82	GO:0007219	Notch signaling pathway
0.65	GO:0007229	integrin-mediated signaling pathway
0.56	GO:0042117	monocyte activation
0.55	GO:0010820	positive regulation of T cell chemotaxis
0.52	GO:0007162	negative regulation of cell adhesion
0.52	GO:0034612	response to tumor necrosis factor
0.52	GO:0030307	positive regulation of cell growth
0.50	GO:0008284	positive regulation of cell proliferation
0.49	GO:0001701	in utero embryonic development

0.70	GO:0004222	metalloendopeptidase activity
0.53	GO:0046872	metal ion binding
0.51	GO:0019901	protein kinase binding
0.50	GO:0042803	protein homodimerization activity
0.39	GO:0017124	SH3 domain binding
0.35	GO:0042169	SH2 domain binding
0.35	GO:0005178	integrin binding

0.55	GO:0097197	tetraspanin-enriched microdomain
0.53	GO:0097038	perinuclear endoplasmic reticulum
0.52	GO:0014069	postsynaptic density
0.50	GO:0005798	Golgi-associated vesicle
0.49	GO:0009986	cell surface
0.48	GO:0005615	extracellular space
0.48	GO:0005794	Golgi apparatus
0.44	GO:0005634	nucleus
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0031984	organelle subcompartment

0.70

GO:0004222

sp|O35599|OPSG_MOUSE
Medium-wave-sensitive opsin 1
Search

0.91	Red-green sensitive cone visual pigment

0.79	GO:0007602	phototransduction
0.78	GO:0007601	visual perception
0.75	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.42	GO:0009584	detection of visible light
0.39	GO:0032467	positive regulation of cytokinesis
0.38	GO:0016038	absorption of visible light
0.38	GO:0070207	protein homotrimerization
0.37	GO:0016039	absorption of UV light
0.36	GO:0001523	retinoid metabolic process

0.79	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.41	GO:0042802	identical protein binding
0.38	GO:0031404	chloride ion binding
0.35	GO:0046983	protein dimerization activity

0.53	GO:0001750	photoreceptor outer segment
0.39	GO:0060342	photoreceptor inner segment membrane
0.37	GO:0044297	cell body
0.37	GO:0060170	ciliary membrane
0.36	GO:0031982	vesicle
0.36	GO:0005794	Golgi apparatus
0.34	GO:0005887	integral component of plasma membrane

sp|O35600|ABCA4_MOUSE
Retinal-specific ATP-binding cassette transporter
Search

ABCA4

0.75	Retinal-specific ATP-binding cassette transporter

0.74	GO:0006649	phospholipid transfer to membrane
0.69	GO:0045494	photoreceptor cell maintenance
0.68	GO:0007601	visual perception
0.64	GO:0045332	phospholipid translocation
0.55	GO:0055085	transmembrane transport
0.38	GO:0007603	phototransduction, visible light
0.38	GO:0001523	retinoid metabolic process
0.33	GO:0015698	inorganic anion transport

0.74	GO:0090555	phosphatidylethanolamine-translocating ATPase activity
0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005452	inorganic anion exchanger activity

0.68	GO:0001750	photoreceptor outer segment
0.57	GO:0005887	integral component of plasma membrane
0.40	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0060170	ciliary membrane

sp|O35601|FYB_MOUSE
FYN-binding protein
Search

0.85	FYN binding protein b

0.74	GO:0006955	immune response
0.59	GO:0072659	protein localization to plasma membrane
0.47	GO:0045576	mast cell activation
0.43	GO:0007165	signal transduction
0.32	GO:0032259	methylation

0.62	GO:0008289	lipid binding
0.47	GO:0005102	receptor binding
0.46	GO:0032403	protein complex binding
0.33	GO:0003677	DNA binding
0.32	GO:0008168	methyltransferase activity

0.73	GO:0015629	actin cytoskeleton
0.45	GO:0005886	plasma membrane
0.40	GO:0030054	cell junction
0.38	GO:0005829	cytosol
0.38	GO:0005634	nucleus
0.33	GO:0046930	pore complex

0.32

GO:0008168

sp|O35602|RX_MOUSE
Retinal homeobox protein Rx
Search

RAX

0.93	Retina and anterior neural fold homeobox

0.74	GO:0043010	camera-type eye development
0.69	GO:0006366	transcription by RNA polymerase II
0.64	GO:0007601	visual perception
0.60	GO:0021854	hypothalamus development
0.57	GO:0060173	limb development
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0007389	pattern specification process
0.52	GO:1902680	positive regulation of RNA biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.57	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.38	GO:0019905	syntaxin binding
0.33	GO:0003746	translation elongation factor activity
0.33	GO:0005537	mannose binding

0.61	GO:0005634	nucleus
0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|O35604|NPC1_MOUSE
Niemann-Pick C1 protein
Search

NPC1

0.96	NPC intracellular cholesterol transporter 1

0.74	GO:0006869	lipid transport
0.59	GO:2000189	positive regulation of cholesterol homeostasis
0.59	GO:0042632	cholesterol homeostasis
0.56	GO:0071404	cellular response to low-density lipoprotein particle stimulus
0.56	GO:0031579	membrane raft organization
0.56	GO:0015850	organic hydroxy compound transport
0.55	GO:0007628	adult walking behavior
0.55	GO:0016242	negative regulation of macroautophagy
0.51	GO:0006914	autophagy
0.51	GO:0071383	cellular response to steroid hormone stimulus

0.76	GO:0005319	lipid transporter activity
0.55	GO:0015485	cholesterol binding
0.37	GO:0019239	deaminase activity
0.35	GO:0104005	hijacked molecular function
0.34	GO:0005515	protein binding
0.34	GO:0004888	transmembrane signaling receptor activity

0.56	GO:0048471	perinuclear region of cytoplasm
0.54	GO:0005635	nuclear envelope
0.52	GO:0005764	lysosome
0.52	GO:0045121	membrane raft
0.51	GO:0005783	endoplasmic reticulum
0.50	GO:0005768	endosome
0.49	GO:0005887	integral component of plasma membrane
0.48	GO:0005794	Golgi apparatus
0.46	GO:0005576	extracellular region
0.40	GO:0098852	lytic vacuole membrane

sp|O35607|BMPR2_MOUSE
Bone morphogenetic protein receptor type-2
Search

BMPR2

0.62	Receptor protein serine/threonine kinase

0.79	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.71	GO:0061036	positive regulation of cartilage development
0.70	GO:0060350	endochondral bone morphogenesis
0.69	GO:0030166	proteoglycan biosynthetic process
0.65	GO:0023014	signal transduction by protein phosphorylation
0.61	GO:0003252	negative regulation of cell proliferation involved in heart valve morphogenesis
0.61	GO:0014916	regulation of lung blood pressure
0.61	GO:1902731	negative regulation of chondrocyte proliferation
0.60	GO:0072577	endothelial cell apoptotic process
0.60	GO:0003186	tricuspid valve morphogenesis

0.79	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.78	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.59	GO:0036122	BMP binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0008144	drug binding
0.35	GO:0019838	growth factor binding
0.35	GO:0046872	metal ion binding

0.56	GO:0005901	caveola
0.56	GO:0005913	cell-cell adherens junction
0.55	GO:0014069	postsynaptic density
0.52	GO:0009986	cell surface
0.49	GO:0005654	nucleoplasm
0.48	GO:0005887	integral component of plasma membrane
0.36	GO:0009925	basal plasma membrane
0.35	GO:0016324	apical plasma membrane
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite

0.79

GO:0004675

sp|O35608|ANGP2_MOUSE
Angiopoietin-2
Search

ANGPT2

0.94	Angiopoietin 2

0.71	GO:0048014	Tie signaling pathway
0.65	GO:0001525	angiogenesis
0.61	GO:0043535	regulation of blood vessel endothelial cell migration
0.61	GO:0050928	negative regulation of positive chemotaxis
0.59	GO:0007162	negative regulation of cell adhesion
0.57	GO:0010596	negative regulation of endothelial cell migration
0.55	GO:0016525	negative regulation of angiogenesis
0.54	GO:0010810	regulation of cell-substrate adhesion
0.51	GO:0072012	glomerulus vasculature development
0.50	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity

0.85	GO:0030971	receptor tyrosine kinase binding
0.38	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.37	GO:0005172	vascular endothelial growth factor receptor binding
0.35	GO:0046872	metal ion binding
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.54	GO:0005615	extracellular space
0.47	GO:0005902	microvillus
0.45	GO:0098857	membrane microdomain
0.39	GO:0005886	plasma membrane
0.36	GO:0005634	nucleus
0.35	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

sp|O35609|SCAM3_MOUSE
Secretory carrier-associated membrane protein 3
Search

SCAMP3

0.68	Secretory carrier-associated membrane protein 3

0.65	GO:0015031	protein transport
0.40	GO:0032526	response to retinoic acid
0.38	GO:0006468	protein phosphorylation
0.37	GO:0006887	exocytosis
0.37	GO:0045721	negative regulation of gluconeogenesis
0.37	GO:0010212	response to ionizing radiation
0.37	GO:0043484	regulation of RNA splicing
0.36	GO:0018212	peptidyl-tyrosine modification
0.35	GO:0006892	post-Golgi vesicle-mediated transport
0.34	GO:0046907	intracellular transport

0.53	GO:0031625	ubiquitin protein ligase binding
0.38	GO:0004672	protein kinase activity
0.36	GO:0042802	identical protein binding
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0019905	syntaxin binding
0.33	GO:0019904	protein domain specific binding

0.42	GO:0043231	intracellular membrane-bounded organelle
0.40	GO:0031982	vesicle
0.40	GO:0098588	bounding membrane of organelle
0.39	GO:0031984	organelle subcompartment
0.39	GO:0043230	extracellular organelle
0.39	GO:0012505	endomembrane system
0.38	GO:0098793	presynapse
0.38	GO:0005615	extracellular space
0.37	GO:0098805	whole membrane
0.36	GO:0044444	cytoplasmic part

sp|O35613|DAXX_MOUSE
Death domain-associated protein 6
Search

DAXX

0.89	Death domain-associated protein 6

0.88	GO:0072738	cellular response to diamide
0.87	GO:1903936	cellular response to sodium arsenite
0.86	GO:0071280	cellular response to copper ion
0.85	GO:0071276	cellular response to cadmium ion
0.85	GO:0030521	androgen receptor signaling pathway
0.84	GO:1901216	positive regulation of neuron death
0.83	GO:0034620	cellular response to unfolded protein
0.80	GO:0034605	cellular response to heat
0.80	GO:0031396	regulation of protein ubiquitination
0.78	GO:0032147	activation of protein kinase activity

0.85	GO:0050681	androgen receptor binding
0.85	GO:0032183	SUMO binding
0.83	GO:0047485	protein N-terminus binding
0.83	GO:0002039	p53 binding
0.80	GO:0030295	protein kinase activator activity
0.80	GO:0003714	transcription corepressor activity
0.79	GO:0003713	transcription coactivator activity
0.77	GO:0042393	histone binding
0.77	GO:0031625	ubiquitin protein ligase binding
0.76	GO:0019901	protein kinase binding

0.84	GO:0016605	PML body
0.76	GO:0000775	chromosome, centromeric region
0.72	GO:0070603	SWI/SNF superfamily-type complex
0.50	GO:0005730	nucleolus
0.48	GO:0005829	cytosol
0.47	GO:0000792	heterochromatin
0.43	GO:0001741	XY body
0.41	GO:0044297	cell body
0.40	GO:0043005	neuron projection
0.40	GO:0005938	cell cortex

sp|O35615|FOG1_MOUSE
Zinc finger protein ZFPM1
Search

ZFPM1

0.83	Zinc finger protein, FOG family member 1

0.57	GO:0006351	transcription, DNA-templated
0.56	GO:0060377	negative regulation of mast cell differentiation
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0060318	definitive erythrocyte differentiation
0.56	GO:0003195	tricuspid valve formation
0.56	GO:0010468	regulation of gene expression
0.55	GO:0003192	mitral valve formation
0.55	GO:0045599	negative regulation of fat cell differentiation
0.55	GO:0060412	ventricular septum morphogenesis

0.53	GO:0001085	RNA polymerase II transcription factor binding
0.52	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0033613	activating transcription factor binding
0.51	GO:0003676	nucleic acid binding
0.42	GO:0003714	transcription corepressor activity
0.34	GO:0001105	RNA polymerase II transcription coactivator activity
0.34	GO:0046872	metal ion binding

0.48	GO:0017053	transcriptional repressor complex
0.46	GO:0005667	transcription factor complex
0.45	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.38	GO:0070013	intracellular organelle lumen
0.36	GO:0044446	intracellular organelle part

sp|O35618|MDM4_MOUSE
Protein Mdm4
Search

sp|O35621|PMM1_MOUSE
Phosphomannomutase 1
Search

PMM1

0.56	Phosphomannomutase

0.81	GO:0009298	GDP-mannose biosynthetic process
0.56	GO:0006013	mannose metabolic process
0.54	GO:1990830	cellular response to leukemia inhibitory factor
0.48	GO:0006487	protein N-linked glycosylation
0.46	GO:0045047	protein targeting to ER
0.39	GO:0090171	chondrocyte morphogenesis
0.37	GO:0048701	embryonic cranial skeleton morphogenesis
0.36	GO:0022008	neurogenesis

0.83	GO:0004615	phosphomannomutase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.54	GO:0043025	neuronal cell body
0.49	GO:0005737	cytoplasm
0.36	GO:0005634	nucleus

0.83	EC:5.4.2.8	GO:0004615
0.83	KEGG:R01818	GO:0004615

sp|O35622|FGF15_MOUSE
Fibroblast growth factor 15
Search

FGF19

0.53	Fibroblast growth factor

0.84	GO:0008543	fibroblast growth factor receptor signaling pathway
0.82	GO:1904252	negative regulation of bile acid metabolic process
0.80	GO:0070857	regulation of bile acid biosynthetic process
0.78	GO:0010894	negative regulation of steroid biosynthetic process
0.76	GO:0010469	regulation of receptor activity
0.75	GO:0046326	positive regulation of glucose import
0.72	GO:0046330	positive regulation of JNK cascade
0.72	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.68	GO:0008284	positive regulation of cell proliferation
0.63	GO:0031327	negative regulation of cellular biosynthetic process

0.85	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.41	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.40	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.39	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.66	GO:0005576	extracellular region
0.33	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.41	EC:2.7.1.153	GO:0046934
0.41	KEGG:R04545	GO:0046934

sp|O35623|BET1_MOUSE
BET1 homolog
Search

BET1

0.96	Putative blocked early in transport 1 log

0.40	GO:0048280	vesicle fusion with Golgi apparatus
0.39	GO:0006888	ER to Golgi vesicle-mediated transport
0.36	GO:0015031	protein transport
0.35	GO:0006901	vesicle coating
0.35	GO:0048199	vesicle targeting, to, from or within Golgi
0.35	GO:0048194	Golgi vesicle budding
0.34	GO:0006461	protein complex assembly

0.40

GO:0019905

syntaxin binding

0.50	GO:0000139	Golgi membrane
0.40	GO:0031201	SNARE complex
0.40	GO:0005801	cis-Golgi network
0.39	GO:0031985	Golgi cisterna
0.37	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.35	GO:0030133	transport vesicle
0.30	GO:0016021	integral component of membrane

sp|O35625|AXIN1_MOUSE
Axin-1
Search

0.74	GO:0016055	Wnt signaling pathway
0.56	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.55	GO:0032147	activation of protein kinase activity
0.55	GO:0051443	positive regulation of ubiquitin-protein transferase activity
0.54	GO:0045732	positive regulation of protein catabolic process
0.51	GO:0045893	positive regulation of transcription, DNA-templated
0.50	GO:0043623	cellular protein complex assembly
0.49	GO:0048320	axial mesoderm formation
0.49	GO:0030910	olfactory placode formation
0.49	GO:0001743	optic placode formation

0.85	GO:0030159	receptor signaling complex scaffold activity
0.59	GO:0070411	I-SMAD binding
0.56	GO:0008013	beta-catenin binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0042802	identical protein binding
0.46	GO:0004871	signal transducer activity
0.44	GO:0005096	GTPase activator activity
0.37	GO:0046983	protein dimerization activity
0.37	GO:0019901	protein kinase binding
0.37	GO:0019904	protein domain specific binding

0.86	GO:0030877	beta-catenin destruction complex
0.57	GO:0016328	lateral plasma membrane
0.54	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0005634	nucleus
0.37	GO:0031410	cytoplasmic vesicle
0.37	GO:1990909	Wnt signalosome
0.36	GO:0005881	cytoplasmic microtubule
0.36	GO:0005829	cytosol
0.35	GO:0005938	cell cortex

sp|O35626|RASD1_MOUSE
Dexamethasone-induced Ras-related protein 1
Search

RASD1

0.97	Activator of G-protein signaling 1

0.61	GO:0007165	signal transduction
0.39	GO:0001963	synaptic transmission, dopaminergic
0.38	GO:0007626	locomotory behavior
0.37	GO:0045892	negative regulation of transcription, DNA-templated
0.34	GO:0033235	positive regulation of protein sumoylation
0.34	GO:0043949	regulation of cAMP-mediated signaling
0.34	GO:0051897	positive regulation of protein kinase B signaling
0.34	GO:0031397	negative regulation of protein ubiquitination

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0031681	G-protein beta-subunit binding
0.34	GO:0043548	phosphatidylinositol 3-kinase binding
0.34	GO:0031624	ubiquitin conjugating enzyme binding

0.55	GO:0016529	sarcoplasmic reticulum
0.38	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005634	nucleus
0.34	GO:0005886	plasma membrane

sp|O35627|NR1I3_MOUSE
Nuclear receptor subfamily 1 group I member 3
Search

NR1I3

0.96	Constitutive androstane nuclear receptor

0.77	GO:0043401	steroid hormone mediated signaling pathway
0.65	GO:0030522	intracellular receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0051254	positive regulation of RNA metabolic process
0.51	GO:0010557	positive regulation of macromolecule biosynthetic process
0.51	GO:0031328	positive regulation of cellular biosynthetic process
0.51	GO:0051253	negative regulation of RNA metabolic process

0.78	GO:0003707	steroid hormone receptor activity
0.67	GO:0004879	nuclear receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.55	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding
0.36	GO:0000989	transcription factor activity, transcription factor binding
0.35	GO:0005515	protein binding
0.34	GO:0035326	enhancer binding

0.61	GO:0005634	nucleus
0.49	GO:0005829	cytosol
0.49	GO:0070013	intracellular organelle lumen
0.44	GO:0044446	intracellular organelle part
0.42	GO:0005856	cytoskeleton
0.33	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|O35632|HYAL2_MOUSE
Hyaluronidase-2
Search

HYAL2

0.72	Hyaluronidase

0.66	GO:0042117	monocyte activation
0.65	GO:0010764	negative regulation of fibroblast migration
0.64	GO:2000484	positive regulation of interleukin-8 secretion
0.64	GO:0030214	hyaluronan catabolic process
0.64	GO:0071493	cellular response to UV-B
0.63	GO:2000778	positive regulation of interleukin-6 secretion
0.63	GO:0061099	negative regulation of protein tyrosine kinase activity
0.62	GO:0060586	multicellular organismal iron ion homeostasis
0.62	GO:0051898	negative regulation of protein kinase B signaling
0.61	GO:0071347	cellular response to interleukin-1

0.85	GO:0004415	hyalurononglucosaminidase activity
0.67	GO:0030294	receptor signaling protein tyrosine kinase inhibitor activity
0.66	GO:0033906	hyaluronoglucuronidase activity
0.64	GO:0104005	hijacked molecular function
0.61	GO:0050431	transforming growth factor beta binding
0.61	GO:0005540	hyaluronic acid binding
0.60	GO:0001105	RNA polymerase II transcription coactivator activity
0.59	GO:0030971	receptor tyrosine kinase binding
0.36	GO:0008080	N-acetyltransferase activity

0.61	GO:0005902	microvillus
0.61	GO:0031362	anchored component of external side of plasma membrane
0.59	GO:0016324	apical plasma membrane
0.59	GO:0030139	endocytic vesicle
0.58	GO:0098857	membrane microdomain
0.58	GO:0048471	perinuclear region of cytoplasm
0.57	GO:0005764	lysosome
0.55	GO:0090575	RNA polymerase II transcription factor complex
0.52	GO:0005829	cytosol
0.37	GO:0000139	Golgi membrane

0.85

EC:3.2.1.35

GO:0004415

sp|O35633|VIAAT_MOUSE
Vesicular inhibitory amino acid transporter
Search

SLC32A1

0.94	Vesicular inhibitory amino acid transporter

0.57	GO:0015816	glycine transport
0.56	GO:0015812	gamma-aminobutyric acid transport
0.44	GO:0003333	amino acid transmembrane transport
0.40	GO:0098700	neurotransmitter loading into synaptic vesicle
0.39	GO:0021766	hippocampus development
0.38	GO:0007568	aging

0.60	GO:0015495	gamma-aminobutyric acid:proton symporter activity
0.57	GO:0015187	glycine transmembrane transporter activity

0.60	GO:0044316	cone cell pedicle
0.58	GO:0044292	dendrite terminus
0.57	GO:0060077	inhibitory synapse
0.55	GO:0051286	cell tip
0.55	GO:0048786	presynaptic active zone
0.40	GO:0030659	cytoplasmic vesicle membrane
0.38	GO:0008021	synaptic vesicle
0.37	GO:0031301	integral component of organelle membrane
0.36	GO:0098805	whole membrane
0.36	GO:0098588	bounding membrane of organelle

sp|O35638|STAG2_MOUSE
Cohesin subunit SA-2
Search

STAG2

0.93	Stromal antigen 2

0.86	GO:0032876	negative regulation of DNA endoreduplication
0.86	GO:1901673	regulation of mitotic spindle assembly
0.78	GO:0007062	sister chromatid cohesion
0.46	GO:0019827	stem cell population maintenance
0.44	GO:0006366	transcription by RNA polymerase II
0.43	GO:0045944	positive regulation of transcription by RNA polymerase II

0.45	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.44	GO:0003682	chromatin binding

0.85	GO:0097431	mitotic spindle pole
0.85	GO:0016363	nuclear matrix
0.84	GO:0008278	cohesin complex
0.72	GO:0000785	chromatin
0.30	GO:0016020	membrane

sp|O35639|ANXA3_MOUSE
Annexin A3
Search

ANXA3

0.61

Annexin

0.61	GO:0043086	negative regulation of catalytic activity
0.59	GO:0050819	negative regulation of coagulation
0.54	GO:0043312	neutrophil degranulation
0.54	GO:0006909	phagocytosis
0.53	GO:0010595	positive regulation of endothelial cell migration
0.52	GO:0045766	positive regulation of angiogenesis
0.51	GO:0051091	positive regulation of DNA binding transcription factor activity
0.49	GO:0042742	defense response to bacterium
0.40	GO:0051592	response to calcium ion
0.39	GO:0010033	response to organic substance

0.81	GO:0005544	calcium-dependent phospholipid binding
0.73	GO:0004859	phospholipase inhibitor activity
0.70	GO:0005509	calcium ion binding
0.55	GO:0048306	calcium-dependent protein binding
0.45	GO:0008429	phosphatidylethanolamine binding
0.42	GO:0044548	S100 protein binding
0.35	GO:0033676	double-stranded DNA-dependent ATPase activity
0.35	GO:0098641	cadherin binding involved in cell-cell adhesion
0.35	GO:0036310	annealing helicase activity
0.34	GO:0042803	protein homodimerization activity

0.56	GO:0042581	specific granule
0.54	GO:0030670	phagocytic vesicle membrane
0.47	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.41	GO:0072563	endothelial microparticle
0.41	GO:0030496	midbody
0.40	GO:0005766	primary lysosome
0.40	GO:0005819	spindle
0.39	GO:0005635	nuclear envelope
0.39	GO:0005654	nucleoplasm

sp|O35640|ANXA8_MOUSE
Annexin A8
Search

0.65

Annexin

0.46	GO:0007599	hemostasis
0.45	GO:0042060	wound healing
0.44	GO:0050817	coagulation
0.42	GO:0050819	negative regulation of coagulation
0.41	GO:1900138	negative regulation of phospholipase A2 activity
0.40	GO:0010256	endomembrane system organization
0.40	GO:0009992	cellular water homeostasis
0.40	GO:1900004	negative regulation of serine-type endopeptidase activity
0.39	GO:0035176	social behavior
0.38	GO:0006874	cellular calcium ion homeostasis

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.41	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.41	GO:0032403	protein complex binding
0.41	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.41	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.39	GO:0048306	calcium-dependent protein binding
0.38	GO:0003779	actin binding
0.38	GO:0050839	cell adhesion molecule binding
0.37	GO:0005102	receptor binding

0.41	GO:0031982	vesicle
0.40	GO:0098805	whole membrane
0.40	GO:0098588	bounding membrane of organelle
0.40	GO:0005829	cytosol
0.39	GO:0012505	endomembrane system
0.37	GO:0043230	extracellular organelle
0.37	GO:0044446	intracellular organelle part
0.36	GO:0005886	plasma membrane
0.36	GO:0005615	extracellular space
0.35	GO:0005634	nucleus

sp|O35643|AP1B1_MOUSE
AP-1 complex subunit beta-1
Search

AP1B1

0.64	AP complex subunit beta

0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.51	GO:0007368	determination of left/right symmetry
0.50	GO:0048513	animal organ development
0.49	GO:0072359	circulatory system development
0.44	GO:0048882	lateral line development
0.44	GO:0050974	detection of mechanical stimulus involved in sensory perception
0.44	GO:2000649	regulation of sodium ion transmembrane transporter activity
0.44	GO:0035315	hair cell differentiation
0.43	GO:1903076	regulation of protein localization to plasma membrane

0.79	GO:0030276	clathrin binding
0.49	GO:0019901	protein kinase binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0005215	transporter activity
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.78	GO:0030131	clathrin adaptor complex
0.47	GO:0005794	Golgi apparatus
0.45	GO:0005829	cytosol
0.37	GO:0030665	clathrin-coated vesicle membrane
0.34	GO:0031984	organelle subcompartment
0.34	GO:0005765	lysosomal membrane
0.30	GO:0031224	intrinsic component of membrane

sp|O35646|CAN6_MOUSE
Calpain-6
Search

CAPN6

0.92	Calpamodulin

0.71	GO:0051493	regulation of cytoskeleton organization
0.61	GO:0006508	proteolysis
0.58	GO:0001578	microtubule bundle formation
0.35	GO:0035556	intracellular signal transduction

0.82	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.53	GO:0008017	microtubule binding
0.39	GO:0005509	calcium ion binding

0.58	GO:0005876	spindle microtubule
0.56	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005829	cytosol
0.34	GO:0009986	cell surface

sp|O35648|CETN3_MOUSE
Centrin-3
Search

CETN3

0.96	Centrin, EF-hand protein, 3

0.36	GO:0031023	microtubule organizing center organization
0.35	GO:0007049	cell cycle
0.35	GO:0007020	microtubule nucleation
0.35	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.34	GO:0043549	regulation of kinase activity
0.34	GO:0051301	cell division

0.70	GO:0005509	calcium ion binding
0.51	GO:0031683	G-protein beta/gamma-subunit complex binding
0.48	GO:0008017	microtubule binding
0.35	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0042802	identical protein binding

0.53	GO:0032391	photoreceptor connecting cilium
0.52	GO:0005814	centriole
0.52	GO:0036064	ciliary basal body
0.51	GO:0005813	centrosome
0.36	GO:0005825	half bridge of spindle pole body
0.36	GO:0000111	nucleotide-excision repair factor 2 complex
0.35	GO:0070390	transcription export complex 2
0.35	GO:0005730	nucleolus

sp|O35652|LHX8_MOUSE
LIM/homeobox protein Lhx8
Search

LHX8

0.93	LIM homeobox 8 variant 1

0.67	GO:0021884	forebrain neuron development
0.65	GO:0008585	female gonad development
0.63	GO:0007611	learning or memory
0.63	GO:0042475	odontogenesis of dentin-containing tooth
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression

0.63	GO:0043565	sequence-specific DNA binding
0.54	GO:0046872	metal ion binding
0.36	GO:0003700	DNA binding transcription factor activity

0.69

GO:0001674

female germ cell nucleus

sp|O35654|DPOD2_MOUSE
DNA polymerase delta subunit 2
Search

POLD2

0.90	LOW QUALITY PROTEIN: DNA polymerase delta subunit 2

0.66	GO:0071897	DNA biosynthetic process
0.65	GO:0006260	DNA replication
0.49	GO:0022616	DNA strand elongation
0.43	GO:0006974	cellular response to DNA damage stimulus
0.35	GO:0000723	telomere maintenance
0.35	GO:0019725	cellular homeostasis
0.34	GO:0006266	DNA ligation
0.34	GO:0051606	detection of stimulus
0.34	GO:0042593	glucose homeostasis
0.34	GO:0022402	cell cycle process

0.70	GO:0003887	DNA-directed DNA polymerase activity
0.54	GO:0003677	DNA binding
0.34	GO:0005536	glucose binding
0.34	GO:0004396	hexokinase activity
0.33	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.53	GO:0043625	delta DNA polymerase complex
0.49	GO:0005654	nucleoplasm
0.32	GO:0030532	small nuclear ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0003887

sp|O35655|PPE1_MOUSE
Serine/threonine-protein phosphatase with EF-hands 1
Search

PPEF1

0.53	Serine/threonine-protein phosphatase with EF-hands 1

0.73	GO:0050906	detection of stimulus involved in sensory perception
0.72	GO:0006470	protein dephosphorylation
0.38	GO:0010801	negative regulation of peptidyl-threonine phosphorylation
0.38	GO:0043409	negative regulation of MAPK cascade
0.37	GO:0022400	regulation of rhodopsin mediated signaling pathway

0.72	GO:0004721	phosphoprotein phosphatase activity
0.71	GO:0030145	manganese ion binding
0.69	GO:0005509	calcium ion binding
0.61	GO:0005506	iron ion binding
0.40	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.39	GO:0051879	Hsp90 protein binding
0.39	GO:0030544	Hsp70 protein binding

0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.72

GO:0004721

sp|O35657|NEUR1_MOUSE
Sialidase-1
Search

NEU1

0.82	Neuraminidase 1 (lysosomal sialidase)

0.59	GO:0009313	oligosaccharide catabolic process
0.52	GO:0006689	ganglioside catabolic process
0.36	GO:2000291	regulation of myoblast proliferation
0.36	GO:0043312	neutrophil degranulation
0.36	GO:0010976	positive regulation of neuron projection development
0.34	GO:0006397	mRNA processing

0.74	GO:0004308	exo-alpha-sialidase activity
0.36	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0004386	helicase activity
0.31	GO:0005509	calcium ion binding

0.58	GO:0005764	lysosome
0.52	GO:0030054	cell junction
0.44	GO:0005775	vacuolar lumen
0.42	GO:0098852	lytic vacuole membrane
0.40	GO:0031410	cytoplasmic vesicle
0.37	GO:0070062	extracellular exosome
0.36	GO:0005886	plasma membrane
0.36	GO:0031983	vesicle lumen
0.35	GO:0009986	cell surface
0.34	GO:0012505	endomembrane system

0.74

EC:3.2.1.18

GO:0004308

sp|O35658|C1QBP_MOUSE
Complement component 1 Q subcomponent-binding protein, mitochondrial
Search

C1QBP

0.86	LOW QUALITY PROTEIN: complement component 1 Q subcomponent-binding protein, mitochondrial

0.61	GO:0039534	negative regulation of MDA-5 signaling pathway
0.60	GO:1901165	positive regulation of trophoblast cell migration
0.60	GO:2000510	positive regulation of dendritic cell chemotaxis
0.60	GO:0039536	negative regulation of RIG-I signaling pathway
0.59	GO:0032695	negative regulation of interleukin-12 production
0.59	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.59	GO:0090023	positive regulation of neutrophil chemotaxis
0.58	GO:0032689	negative regulation of interferon-gamma production
0.58	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.58	GO:0030449	regulation of complement activation

0.62	GO:0030984	kininogen binding
0.60	GO:0001849	complement component C1q binding
0.57	GO:0005540	hyaluronic acid binding
0.55	GO:0003714	transcription corepressor activity
0.50	GO:0008134	transcription factor binding
0.44	GO:0031690	adrenergic receptor binding
0.44	GO:0097177	mitochondrial ribosome binding
0.40	GO:0005080	protein kinase C binding
0.40	GO:0003729	mRNA binding
0.37	GO:0004386	helicase activity

0.75	GO:0005759	mitochondrial matrix
0.52	GO:0009986	cell surface
0.48	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.43	GO:0005886	plasma membrane
0.39	GO:0005576	extracellular region
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.32

GO:0003887

sp|O35659|GLP1R_MOUSE
Glucagon-like peptide 1 receptor
Search

GLP1R

0.96	Glucagon like peptide 1 receptor

0.82	GO:0071377	cellular response to glucagon stimulus
0.70	GO:0007166	cell surface receptor signaling pathway
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.59	GO:0019933	cAMP-mediated signaling
0.57	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.54	GO:0045777	positive regulation of blood pressure
0.52	GO:0008016	regulation of heart contraction
0.51	GO:0007611	learning or memory
0.45	GO:0010906	regulation of glucose metabolic process
0.44	GO:0006950	response to stress

0.83	GO:0004967	glucagon receptor activity
0.64	GO:0044508	glucagon-like peptide 1 receptor activity
0.57	GO:0016519	gastric inhibitory peptide receptor activity
0.45	GO:0017046	peptide hormone binding
0.34	GO:0003777	microtubule motor activity
0.33	GO:0005515	protein binding

0.51	GO:0005886	plasma membrane
0.38	GO:0005622	intracellular
0.34	GO:0031982	vesicle
0.34	GO:0012505	endomembrane system
0.33	GO:1902494	catalytic complex
0.33	GO:0043234	protein complex
0.33	GO:0043228	non-membrane-bounded organelle
0.33	GO:0044422	organelle part
0.30	GO:0016021	integral component of membrane

sp|O35660|GSTM6_MOUSE
Glutathione S-transferase Mu 6
Search

0.42	Glutathione S-transferase

0.52	GO:0018916	nitrobenzene metabolic process
0.49	GO:0006749	glutathione metabolic process
0.48	GO:0070458	cellular detoxification of nitrogen compound
0.47	GO:0042178	xenobiotic catabolic process
0.43	GO:0035690	cellular response to drug
0.42	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity
0.42	GO:0071415	cellular response to purine-containing compound
0.42	GO:0043651	linoleic acid metabolic process
0.42	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
0.42	GO:0031000	response to caffeine

0.78	GO:0004364	glutathione transferase activity
0.50	GO:0043295	glutathione binding
0.49	GO:0042802	identical protein binding
0.45	GO:0019899	enzyme binding
0.45	GO:0046983	protein dimerization activity
0.40	GO:0004602	glutathione peroxidase activity
0.38	GO:0005102	receptor binding
0.34	GO:0005496	steroid binding
0.34	GO:0016151	nickel cation binding
0.33	GO:0003735	structural constituent of ribosome

0.53	GO:0045171	intercellular bridge
0.47	GO:0005829	cytosol
0.41	GO:0016529	sarcoplasmic reticulum
0.36	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome
0.34	GO:0032991	macromolecular complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0005886	plasma membrane

0.78

EC:2.5.1.18

GO:0004364

sp|O35664|INAR2_MOUSE
Interferon alpha/beta receptor 2
Search

IFNAR2

0.96	Interferon alpha and beta receptor subunit 2

0.74	GO:0060337	type I interferon signaling pathway
0.70	GO:0035455	response to interferon-alpha
0.70	GO:0035456	response to interferon-beta
0.62	GO:0051607	defense response to virus
0.50	GO:0008283	cell proliferation
0.46	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0007259	JAK-STAT cascade
0.37	GO:0060338	regulation of type I interferon-mediated signaling pathway

0.77	GO:0004905	type I interferon receptor activity
0.60	GO:0019901	protein kinase binding
0.55	GO:0019962	type I interferon binding

0.54	GO:0005887	integral component of plasma membrane
0.48	GO:0005615	extracellular space
0.33	GO:0005622	intracellular

sp|O35668|HAP1_MOUSE
Huntingtin-associated protein 1
Search

HAP1

0.96	LOW QUALITY PROTEIN: huntingtin-associated protein 1

0.85	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
0.85	GO:1902513	regulation of organelle transport along microtubule
0.85	GO:1902857	positive regulation of non-motile cilium assembly
0.85	GO:0021979	hypothalamus cell differentiation
0.84	GO:0008089	anterograde axonal transport
0.83	GO:0048011	neurotrophin TRK receptor signaling pathway
0.80	GO:0072384	organelle transport along microtubule
0.79	GO:0099518	vesicle cytoskeletal trafficking
0.79	GO:0021549	cerebellum development
0.76	GO:0017157	regulation of exocytosis

0.62	GO:0048403	brain-derived neurotrophic factor binding
0.58	GO:0044325	ion channel binding
0.48	GO:0005102	receptor binding
0.46	GO:0019904	protein domain specific binding
0.44	GO:0042802	identical protein binding
0.34	GO:0000991	transcription factor activity, core RNA polymerase II binding
0.34	GO:0003696	satellite DNA binding
0.34	GO:0003723	RNA binding
0.33	GO:0005267	potassium channel activity
0.32	GO:0016779	nucleotidyltransferase activity

0.82	GO:1904115	axon cytoplasm
0.81	GO:0016234	inclusion body
0.78	GO:0005776	autophagosome
0.77	GO:0005814	centriole
0.73	GO:0005813	centrosome
0.69	GO:0031410	cytoplasmic vesicle
0.54	GO:0005764	lysosome
0.54	GO:0098793	presynapse
0.52	GO:0030054	cell junction
0.50	GO:0012505	endomembrane system

0.32

EC:2.7.7

GO:0016779

sp|O35671|ITBP1_MOUSE
Integrin beta-1-binding protein 1
Search

ITGB1BP1

0.97	Integrin subunit beta 1 binding protein 1

0.78	GO:0007229	integrin-mediated signaling pathway
0.64	GO:0090315	negative regulation of protein targeting to membrane
0.63	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.63	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration
0.62	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis
0.62	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading
0.62	GO:0051895	negative regulation of focal adhesion assembly
0.62	GO:0010764	negative regulation of fibroblast migration
0.62	GO:0032148	activation of protein kinase B activity
0.61	GO:0033622	integrin activation

0.59	GO:0005178	integrin binding
0.58	GO:0005092	GDP-dissociation inhibitor activity
0.55	GO:0019901	protein kinase binding
0.52	GO:0008565	protein transporter activity
0.36	GO:0008022	protein C-terminus binding

0.58	GO:0001726	ruffle
0.58	GO:0030027	lamellipodium
0.56	GO:0048471	perinuclear region of cytoplasm
0.56	GO:0016604	nuclear body
0.54	GO:0005815	microtubule organizing center
0.52	GO:0005829	cytosol
0.43	GO:0071944	cell periphery
0.42	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|O35674|ADA19_MOUSE
Disintegrin and metalloproteinase domain-containing protein 19
Search

ADAM19

0.97	Disintegrin and metalloproteinase domain-containing protein 19

0.82	GO:0006509	membrane protein ectodomain proteolysis
0.63	GO:0007229	integrin-mediated signaling pathway
0.55	GO:0007507	heart development
0.35	GO:0030198	extracellular matrix organization

0.75	GO:0017124	SH3 domain binding
0.70	GO:0004222	metalloendopeptidase activity
0.53	GO:0046872	metal ion binding

0.68	GO:0005794	Golgi apparatus
0.35	GO:0009897	external side of plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004222

sp|O35678|MGLL_MOUSE
Monoglyceride lipase
Search

MGLL

0.91	Monoglyceride lipase

0.54	GO:0009966	regulation of signal transduction
0.50	GO:0006629	lipid metabolic process
0.49	GO:0051930	regulation of sensory perception of pain
0.48	GO:0006690	icosanoid metabolic process
0.47	GO:0050727	regulation of inflammatory response
0.46	GO:0060292	long term synaptic depression
0.45	GO:0030516	regulation of axon extension
0.42	GO:0072330	monocarboxylic acid biosynthetic process
0.41	GO:0044248	cellular catabolic process
0.41	GO:0097756	negative regulation of blood vessel diameter

0.66	GO:0047372	acylglycerol lipase activity
0.45	GO:0042803	protein homodimerization activity
0.40	GO:0004622	lysophospholipase activity

0.66	GO:0005654	nucleoplasm
0.47	GO:0043196	varicosity
0.45	GO:0019898	extrinsic component of membrane
0.43	GO:0005829	cytosol
0.42	GO:0045202	synapse
0.40	GO:0005811	lipid droplet
0.38	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.66

EC:3.1.1.23

GO:0047372

sp|O35679|ISK4_MOUSE
Serine protease inhibitor Kazal-type 4
Search

SPINK4

0.91	Serine protease inhibitor Kazal-type 4

0.61	GO:0010951	negative regulation of endopeptidase activity
0.53	GO:0042493	response to drug
0.50	GO:0043113	receptor clustering
0.49	GO:0006508	proteolysis
0.47	GO:1903831	signal transduction involved in cellular response to ammonium ion
0.47	GO:1902572	negative regulation of serine-type peptidase activity
0.47	GO:1900003	regulation of serine-type endopeptidase activity
0.47	GO:0060046	regulation of acrosome reaction
0.45	GO:0032870	cellular response to hormone stimulus
0.44	GO:1901701	cellular response to oxygen-containing compound

0.62	GO:0004867	serine-type endopeptidase inhibitor activity
0.50	GO:0008233	peptidase activity
0.48	GO:0043236	laminin binding
0.47	GO:0005509	calcium ion binding
0.42	GO:0099602	neurotransmitter receptor regulator activity
0.42	GO:0002162	dystroglycan binding
0.40	GO:0005539	glycosaminoglycan binding
0.39	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.39	GO:0033691	sialic acid binding
0.38	GO:0043395	heparan sulfate proteoglycan binding

0.53	GO:0005576	extracellular region
0.45	GO:0001669	acrosomal vesicle
0.41	GO:0045178	basal part of cell
0.41	GO:0031594	neuromuscular junction
0.40	GO:0030424	axon
0.39	GO:0005886	plasma membrane
0.37	GO:0098857	membrane microdomain
0.37	GO:0030054	cell junction
0.36	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.50

GO:0008233

sp|O35680|RT12_MOUSE
28S ribosomal protein S12, mitochondrial
Search

MRPS12

0.97	Mitochondrial ribosomal protein S12

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.32	GO:0016746	transferase activity, transferring acyl groups
0.32	GO:0016787	hydrolase activity

0.70	GO:0015935	small ribosomal subunit
0.53	GO:0005761	mitochondrial ribosome
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

EC:2.3

GO:0016746

sp|O35681|SYT3_MOUSE
Synaptotagmin-3
Search

SYT3

0.87	Synaptotagmin III

0.72	GO:0017156	calcium ion regulated exocytosis
0.70	GO:0017158	regulation of calcium ion-dependent exocytosis
0.61	GO:1903861	positive regulation of dendrite extension
0.51	GO:0048489	synaptic vesicle transport
0.50	GO:0099504	synaptic vesicle cycle
0.50	GO:0006906	vesicle fusion
0.50	GO:0099643	signal release from synapse
0.50	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.50	GO:0050796	regulation of insulin secretion
0.48	GO:0006836	neurotransmitter transport

0.51	GO:0000149	SNARE binding
0.50	GO:0005544	calcium-dependent phospholipid binding
0.50	GO:0030276	clathrin binding
0.46	GO:0005509	calcium ion binding
0.41	GO:0001786	phosphatidylserine binding
0.41	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.39	GO:0042803	protein homodimerization activity
0.38	GO:0046982	protein heterodimerization activity

0.54	GO:0005768	endosome
0.49	GO:0098793	presynapse
0.40	GO:0005886	plasma membrane
0.40	GO:0070382	exocytic vesicle
0.36	GO:0030658	transport vesicle membrane
0.30	GO:0016021	integral component of membrane

sp|O35682|MYADM_MOUSE
Myeloid-associated differentiation marker
Search

MYADM

0.94	Myeloid-associated differentiation marker

0.59	GO:0090038	negative regulation of protein kinase C signaling
0.58	GO:0034115	negative regulation of heterotypic cell-cell adhesion
0.57	GO:0061028	establishment of endothelial barrier
0.57	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.56	GO:0031579	membrane raft organization
0.55	GO:0072659	protein localization to plasma membrane
0.54	GO:0030837	negative regulation of actin filament polymerization
0.54	GO:0030335	positive regulation of cell migration
0.51	GO:0001933	negative regulation of protein phosphorylation
0.48	GO:0010629	negative regulation of gene expression

0.55	GO:0001726	ruffle
0.54	GO:0030864	cortical actin cytoskeleton
0.53	GO:0045121	membrane raft
0.52	GO:0005911	cell-cell junction
0.42	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|O35683|NDUA1_MOUSE
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
Search

NDUFA1

0.42	Mitochondrial NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1

0.65	GO:0032981	mitochondrial respiratory chain complex I assembly
0.38	GO:0055114	oxidation-reduction process
0.37	GO:0016310	phosphorylation
0.34	GO:0046034	ATP metabolic process
0.34	GO:0006091	generation of precursor metabolites and energy

0.37	GO:0003954	NADH dehydrogenase activity
0.36	GO:0016301	kinase activity
0.35	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor

0.63	GO:0005747	mitochondrial respiratory chain complex I
0.53	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.37

EC:1.6.99.3

GO:0003954

sp|O35684|NEUS_MOUSE
Neuroserpin
Search

SERPINI1

0.96	Putative neuroserpin is a inhibitory member of the serine proteinase inhibitor

0.54	GO:0010951	negative regulation of endopeptidase activity
0.39	GO:0010976	positive regulation of neuron projection development
0.38	GO:0030155	regulation of cell adhesion
0.35	GO:0006508	proteolysis
0.35	GO:0007422	peripheral nervous system development
0.34	GO:0007417	central nervous system development
0.33	GO:0015986	ATP synthesis coupled proton transport
0.33	GO:0042270	protection from natural killer cell mediated cytotoxicity
0.33	GO:0002448	mast cell mediated immunity
0.33	GO:0033668	negative regulation by symbiont of host apoptotic process

0.56	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0008233	peptidase activity
0.33	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.33	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0002020	protease binding
0.32	GO:0005509	calcium ion binding
0.31	GO:0016740	transferase activity

0.73	GO:0005615	extracellular space
0.60	GO:0060205	cytoplasmic vesicle lumen
0.56	GO:0043025	neuronal cell body
0.55	GO:0030141	secretory granule
0.36	GO:1903561	extracellular vesicle
0.34	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.32	GO:0005794	Golgi apparatus
0.32	GO:0005654	nucleoplasm
0.32	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane

0.35

GO:0008233

sp|O35685|NUDC_MOUSE
Nuclear migration protein nudC
Search

NUDC

0.90	Nuclear migration protein nudC

0.58	GO:0032502	developmental process
0.53	GO:0060271	cilium assembly
0.52	GO:0006457	protein folding
0.49	GO:0032501	multicellular organismal process
0.42	GO:0051301	cell division
0.42	GO:0007049	cell cycle
0.39	GO:0007097	nuclear migration
0.38	GO:0043434	response to peptide hormone
0.37	GO:0008283	cell proliferation
0.36	GO:0007059	chromosome segregation

0.72	GO:0045296	cadherin binding
0.54	GO:0051082	unfolded protein binding

0.61	GO:0005829	cytosol
0.44	GO:0005874	microtubule
0.39	GO:0005634	nucleus
0.36	GO:0005794	Golgi apparatus
0.36	GO:0031974	membrane-enclosed lumen
0.30	GO:0016020	membrane

sp|O35690|PHX2B_MOUSE
Paired mesoderm homeobox protein 2B
Search

PHOX2A

0.92	Paired mesoderm homeobox protein 2B

0.74	GO:0003357	noradrenergic neuron differentiation
0.70	GO:0048857	neural nucleus development
0.68	GO:0048485	sympathetic nervous system development
0.67	GO:0043576	regulation of respiratory gaseous exchange
0.67	GO:0030902	hindbrain development
0.67	GO:0048486	parasympathetic nervous system development
0.66	GO:0021545	cranial nerve development
0.63	GO:0021953	central nervous system neuron differentiation
0.61	GO:0003360	brainstem development
0.60	GO:1901166	neural crest cell migration involved in autonomic nervous system development

0.60	GO:0043565	sequence-specific DNA binding
0.60	GO:0001012	RNA polymerase II regulatory region DNA binding
0.56	GO:0003690	double-stranded DNA binding
0.55	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.60	GO:0005634	nucleus
0.57	GO:0000785	chromatin
0.53	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

sp|O35691|PININ_MOUSE
Pinin
Search

PNN

0.95	Pinin, desmosome associated protein (Fragment)

0.52	GO:0007155	cell adhesion
0.49	GO:0014033	neural crest cell differentiation
0.46	GO:0008380	RNA splicing
0.45	GO:0006397	mRNA processing
0.41	GO:0006351	transcription, DNA-templated
0.40	GO:1903506	regulation of nucleic acid-templated transcription
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression

0.42	GO:0003677	DNA binding
0.38	GO:0003723	RNA binding
0.36	GO:0005515	protein binding
0.36	GO:0005198	structural molecule activity

0.80	GO:0035145	exon-exon junction complex
0.76	GO:0071013	catalytic step 2 spliceosome
0.74	GO:0016607	nuclear speck
0.57	GO:0005911	cell-cell junction
0.49	GO:0070161	anchoring junction
0.39	GO:0005882	intermediate filament
0.35	GO:0005737	cytoplasm
0.35	GO:0005886	plasma membrane
0.33	GO:0030424	axon

sp|O35696|SIA8B_MOUSE
Alpha-2,8-sialyltransferase 8B
Search

ST8SIA2

0.97	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2

0.83	GO:0097503	sialylation
0.74	GO:0006486	protein glycosylation
0.60	GO:0001574	ganglioside biosynthetic process
0.57	GO:0006491	N-glycan processing
0.50	GO:0009311	oligosaccharide metabolic process
0.34	GO:0007399	nervous system development

0.84	GO:0008373	sialyltransferase activity
0.36	GO:0033691	sialic acid binding
0.33	GO:0005515	protein binding

0.71	GO:0005794	Golgi apparatus
0.54	GO:0055037	recycling endosome
0.52	GO:0005769	early endosome
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.84

EC:2.4.99

GO:0008373

sp|O35698|RBY1A_MOUSE
RNA-binding motif protein, Y chromosome, family 1 member A1
Search

0.74	RNA binding motif protein, X-linked

0.43	GO:0006397	mRNA processing
0.43	GO:0008380	RNA splicing
0.41	GO:0002244	hematopoietic progenitor cell differentiation
0.40	GO:0006509	membrane protein ectodomain proteolysis
0.39	GO:0071347	cellular response to interleukin-1
0.39	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.38	GO:0006366	transcription by RNA polymerase II
0.38	GO:0048518	positive regulation of biological process
0.37	GO:0051259	protein oligomerization
0.37	GO:0006357	regulation of transcription by RNA polymerase II

0.59	GO:0003723	RNA binding
0.40	GO:0042802	identical protein binding
0.39	GO:0001047	core promoter binding
0.38	GO:0003682	chromatin binding
0.37	GO:0019904	protein domain specific binding
0.33	GO:0043022	ribosome binding
0.32	GO:0046983	protein dimerization activity

0.41	GO:0005634	nucleus
0.40	GO:0019013	viral nucleocapsid
0.40	GO:0030529	intracellular ribonucleoprotein complex
0.39	GO:0000791	euchromatin
0.39	GO:0070062	extracellular exosome
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:1902494	catalytic complex
0.34	GO:0005829	cytosol
0.33	GO:0045171	intercellular bridge
0.30	GO:0031224	intrinsic component of membrane

sp|O35701|MATN3_MOUSE
Matrilin-3
Search

0.64	Matrilin 3

0.51	GO:0051216	cartilage development
0.39	GO:0003416	endochondral bone growth
0.39	GO:0060350	endochondral bone morphogenesis
0.39	GO:0030500	regulation of bone mineralization
0.38	GO:0000904	cell morphogenesis involved in differentiation
0.38	GO:0048729	tissue morphogenesis

0.68	GO:0005509	calcium ion binding
0.68	GO:0005201	extracellular matrix structural constituent

0.63	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0044425	membrane part

sp|O35704|SPTC1_MOUSE
Serine palmitoyltransferase 1
Search

SPTLC1

0.90	Serine palmitoyltransferase long chain base subunit 1

0.57	GO:1904502	regulation of lipophagy
0.55	GO:0046513	ceramide biosynthetic process
0.54	GO:0016239	positive regulation of macroautophagy
0.53	GO:0046511	sphinganine biosynthetic process
0.52	GO:0006686	sphingomyelin biosynthetic process
0.52	GO:0046512	sphingosine biosynthetic process
0.38	GO:0006298	mismatch repair

0.67	GO:0030170	pyridoxal phosphate binding
0.57	GO:0004758	serine C-palmitoyltransferase activity
0.38	GO:0030983	mismatched DNA binding
0.35	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.34	GO:0008483	transaminase activity

0.57	GO:0035339	SPOTS complex
0.30	GO:0031224	intrinsic component of membrane

0.57	EC:2.3.1.50	GO:0004758
0.57	KEGG:R01281	GO:0004758

sp|O35709|ENC1_MOUSE
Ectoderm-neural cortex protein 1
Search

ENC1

0.76	Ectodermal-neural cortex

0.74	GO:0007399	nervous system development
0.58	GO:0010499	proteasomal ubiquitin-independent protein catabolic process
0.54	GO:0017148	negative regulation of translation
0.52	GO:0016567	protein ubiquitination
0.39	GO:0031346	positive regulation of cell projection organization
0.39	GO:0010720	positive regulation of cell development
0.39	GO:0051962	positive regulation of nervous system development
0.39	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.38	GO:0030154	cell differentiation

0.74

GO:0003779

actin binding

0.57	GO:0031463	Cul3-RING ubiquitin ligase complex
0.40	GO:0016363	nuclear matrix
0.40	GO:0005737	cytoplasm
0.39	GO:0043025	neuronal cell body
0.38	GO:0000790	nuclear chromatin
0.38	GO:0005730	nucleolus
0.37	GO:0005654	nucleoplasm
0.35	GO:0005856	cytoskeleton

sp|O35710|NOCT_MOUSE
Nocturnin
Search

NOCT

0.96

Nocturnin

0.82	GO:0007623	circadian rhythm
0.75	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.57	GO:0033962	cytoplasmic mRNA processing body assembly
0.56	GO:0045668	negative regulation of osteoblast differentiation
0.56	GO:0048255	mRNA stabilization
0.56	GO:0045600	positive regulation of fat cell differentiation
0.55	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.54	GO:0042752	regulation of circadian rhythm
0.54	GO:0045995	regulation of embryonic development
0.54	GO:0032496	response to lipopolysaccharide

0.85	GO:0004535	poly(A)-specific ribonuclease activity
0.51	GO:0003729	mRNA binding
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity

0.54	GO:0000932	P-body
0.53	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

0.85

EC:3.1.13.4

GO:0004535

sp|O35711|LIPB2_MOUSE
Liprin-beta-2
Search

PPFIBP2

0.91	Putative lar transmembrane tyrosine phosphatase-interacting protein liprin

0.71

GO:0042802

identical protein binding

0.43	GO:0005615	extracellular space
0.37	GO:0005829	cytosol
0.30	GO:0044425	membrane part

sp|O35714|TNR18_MOUSE
Tumor necrosis factor receptor superfamily member 18
Search

TNFRSF18

0.96	Tumor necrosis factor receptor superfamily member 18

0.85	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.78	GO:0043066	negative regulation of apoptotic process
0.56	GO:0045785	positive regulation of cell adhesion
0.53	GO:0032496	response to lipopolysaccharide
0.53	GO:0097190	apoptotic signaling pathway
0.52	GO:0006954	inflammatory response
0.52	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.51	GO:0002687	positive regulation of leukocyte migration
0.50	GO:0042127	regulation of cell proliferation
0.49	GO:0006955	immune response

0.86	GO:0005031	tumor necrosis factor-activated receptor activity
0.38	GO:0005515	protein binding

0.66	GO:0005887	integral component of plasma membrane
0.57	GO:0009897	external side of plasma membrane
0.39	GO:0005576	extracellular region

sp|O35716|SOCS1_MOUSE
Suppressor of cytokine signaling 1
Search

SOCS1

0.95	Suppressor of cytokine signaling

0.85	GO:0060330	regulation of response to interferon-gamma
0.85	GO:0046426	negative regulation of JAK-STAT cascade
0.72	GO:0001959	regulation of cytokine-mediated signaling pathway
0.67	GO:0016567	protein ubiquitination
0.63	GO:0010533	regulation of activation of Janus kinase activity
0.62	GO:0042509	regulation of tyrosine phosphorylation of STAT protein
0.62	GO:0045591	positive regulation of regulatory T cell differentiation
0.61	GO:0046627	negative regulation of insulin receptor signaling pathway
0.61	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation
0.60	GO:0035556	intracellular signal transduction

0.65	GO:0005159	insulin-like growth factor receptor binding
0.59	GO:0019210	kinase inhibitor activity
0.56	GO:0019901	protein kinase binding
0.48	GO:0019887	protein kinase regulator activity
0.46	GO:0008269	JAK pathway signal transduction adaptor activity
0.33	GO:0003677	DNA binding
0.32	GO:0003924	GTPase activity
0.32	GO:0005525	GTP binding

0.56	GO:0036464	cytoplasmic ribonucleoprotein granule
0.51	GO:0005654	nucleoplasm
0.38	GO:0031410	cytoplasmic vesicle
0.36	GO:0005829	cytosol
0.32	GO:0000786	nucleosome

sp|O35717|SOCS2_MOUSE
Suppressor of cytokine signaling 2
Search

SOCS2

0.97	Suppressor of cytokine signaling 2

0.85	GO:0046426	negative regulation of JAK-STAT cascade
0.77	GO:0001558	regulation of cell growth
0.66	GO:0016567	protein ubiquitination
0.62	GO:0035556	intracellular signal transduction
0.61	GO:0040015	negative regulation of multicellular organism growth
0.60	GO:0060396	growth hormone receptor signaling pathway
0.59	GO:0032355	response to estradiol
0.59	GO:0061377	mammary gland lobule development
0.58	GO:0007595	lactation
0.57	GO:0045666	positive regulation of neuron differentiation

0.85	GO:0008269	JAK pathway signal transduction adaptor activity
0.85	GO:0005159	insulin-like growth factor receptor binding
0.60	GO:0005131	growth hormone receptor binding
0.48	GO:0019210	kinase inhibitor activity
0.47	GO:0019887	protein kinase regulator activity
0.35	GO:0005070	SH3/SH2 adaptor activity
0.35	GO:0019901	protein kinase binding
0.35	GO:0070513	death domain binding
0.32	GO:0003779	actin binding

0.49	GO:0005737	cytoplasm
0.35	GO:0035770	ribonucleoprotein granule
0.34	GO:0005654	nucleoplasm

sp|O35718|SOCS3_MOUSE
Suppressor of cytokine signaling 3
Search

SOCS3

0.97	Suppressor of cytokine signaling 3

0.85	GO:0007259	JAK-STAT cascade
0.78	GO:0043066	negative regulation of apoptotic process
0.68	GO:0016567	protein ubiquitination
0.64	GO:0060708	spongiotrophoblast differentiation
0.64	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein
0.64	GO:0046627	negative regulation of insulin receptor signaling pathway
0.63	GO:0060670	branching involved in labyrinthine layer morphogenesis
0.63	GO:0060707	trophoblast giant cell differentiation
0.62	GO:0060674	placenta blood vessel development
0.61	GO:0050728	negative regulation of inflammatory response

0.62	GO:0001784	phosphotyrosine residue binding
0.49	GO:0004860	protein kinase inhibitor activity
0.36	GO:0008269	JAK pathway signal transduction adaptor activity
0.36	GO:0005159	insulin-like growth factor receptor binding

0.45

GO:0005622

intracellular

sp|O35719|RA51B_MOUSE
DNA repair protein RAD51 homolog 2
Search

RAD51B

0.97	DNA repair protein RAD51 like protein 2

0.77	GO:0000724	double-strand break repair via homologous recombination
0.52	GO:0001832	blastocyst growth
0.52	GO:0061053	somite development
0.51	GO:0042148	strand invasion
0.51	GO:0090735	DNA repair complex assembly
0.50	GO:0006312	mitotic recombination
0.50	GO:0008284	positive regulation of cell proliferation
0.49	GO:0010212	response to ionizing radiation
0.49	GO:0007131	reciprocal meiotic recombination
0.47	GO:0065004	protein-DNA complex assembly

0.69	GO:0008094	DNA-dependent ATPase activity
0.55	GO:0003677	DNA binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0000150	recombinase activity
0.45	GO:0004520	endodeoxyribonuclease activity
0.34	GO:0005515	protein binding
0.32	GO:0008270	zinc ion binding

0.85	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex
0.46	GO:0005657	replication fork
0.34	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

sp|O35723|DNJB3_MOUSE
DnaJ homolog subfamily B member 3
Search

DNAJB6

0.87	DnaJ like protein subfamily B member 3

0.74	GO:0090084	negative regulation of inclusion body assembly
0.68	GO:0045109	intermediate filament organization
0.66	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.63	GO:0032781	positive regulation of ATPase activity
0.59	GO:0060715	syncytiotrophoblast cell differentiation involved in labyrinthine layer development
0.59	GO:0032880	regulation of protein localization
0.58	GO:0006457	protein folding
0.57	GO:0060710	chorio-allantoic fusion
0.57	GO:0060717	chorion development
0.54	GO:0030036	actin cytoskeleton organization

0.64	GO:0051087	chaperone binding
0.63	GO:0001671	ATPase activator activity
0.61	GO:0031072	heat shock protein binding
0.60	GO:0051082	unfolded protein binding
0.51	GO:0044183	protein binding involved in protein folding
0.44	GO:0042802	identical protein binding
0.41	GO:0003677	DNA binding

0.70	GO:0030018	Z disc
0.68	GO:0048471	perinuclear region of cytoplasm
0.59	GO:0005634	nucleus
0.58	GO:0005829	cytosol
0.54	GO:0031974	membrane-enclosed lumen
0.52	GO:0044446	intracellular organelle part
0.48	GO:0001669	acrosomal vesicle
0.44	GO:0070062	extracellular exosome
0.43	GO:0015630	microtubule cytoskeleton
0.40	GO:0031975	envelope

sp|O35728|CP4AE_MOUSE
Cytochrome P450 4A14
Search

0.97	Fatty acid omega-hydroxylase

0.53	GO:0055114	oxidation-reduction process
0.45	GO:0006690	icosanoid metabolic process
0.44	GO:0033559	unsaturated fatty acid metabolic process
0.43	GO:0001676	long-chain fatty acid metabolic process
0.41	GO:0048252	lauric acid metabolic process
0.41	GO:1901569	fatty acid derivative catabolic process
0.39	GO:0009062	fatty acid catabolic process
0.39	GO:1901616	organic hydroxy compound catabolic process
0.39	GO:0001822	kidney development
0.38	GO:1901570	fatty acid derivative biosynthetic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.65	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.44	GO:0103002	16-hydroxypalmitate dehydrogenase activity
0.36	GO:0050544	arachidonic acid binding
0.34	GO:0019825	oxygen binding

0.44	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0016324	apical plasma membrane
0.39	GO:0031090	organelle membrane
0.39	GO:0005615	extracellular space
0.34	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

0.68

EC:1.14

GO:0016705

sp|O35730|RING1_MOUSE
E3 ubiquitin-protein ligase RING1
Search

RING1

0.50	Ring finger protein 1

0.66	GO:0035518	histone H2A monoubiquitination
0.59	GO:0048593	camera-type eye morphogenesis
0.58	GO:0009952	anterior/posterior pattern specification
0.56	GO:0045892	negative regulation of transcription, DNA-templated
0.51	GO:0050790	regulation of catalytic activity
0.39	GO:0006351	transcription, DNA-templated
0.37	GO:0070317	negative regulation of G0 to G1 transition

0.59	GO:0097027	ubiquitin-protein transferase activator activity
0.56	GO:0003682	chromatin binding
0.50	GO:0016874	ligase activity
0.38	GO:0046872	metal ion binding
0.37	GO:0016740	transferase activity
0.36	GO:0005515	protein binding

0.85	GO:0035102	PRC1 complex
0.64	GO:0001739	sex chromatin
0.58	GO:0016604	nuclear body
0.53	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.50

GO:0016874

sp|O35732|CFLAR_MOUSE
CASP8 and FADD-like apoptosis regulator
Search

CFLAR

0.96	CASP8 and FADD like apoptosis regulator

0.73	GO:0042981	regulation of apoptotic process
0.64	GO:0060544	regulation of necroptotic process
0.60	GO:0006915	apoptotic process
0.59	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.59	GO:0043069	negative regulation of programmed cell death
0.58	GO:0006508	proteolysis
0.56	GO:0009968	negative regulation of signal transduction
0.54	GO:0043085	positive regulation of catalytic activity
0.45	GO:0072126	positive regulation of glomerular mesangial cell proliferation
0.45	GO:0071549	cellular response to dexamethasone stimulus

0.72	GO:0004197	cysteine-type endopeptidase activity
0.61	GO:0002020	protease binding
0.55	GO:0008047	enzyme activator activity
0.45	GO:0005123	death receptor binding
0.41	GO:0032403	protein complex binding
0.39	GO:0061134	peptidase regulator activity
0.38	GO:0046982	protein heterodimerization activity
0.34	GO:0017124	SH3 domain binding
0.34	GO:0019901	protein kinase binding

0.65	GO:0031264	death-inducing signaling complex
0.64	GO:0097342	ripoptosome
0.42	GO:0098857	membrane microdomain
0.35	GO:0043293	apoptosome
0.33	GO:0005634	nucleus

0.72

GO:0004197

sp|O35737|HNRH1_MOUSE
Heterogeneous nuclear ribonucleoprotein H
Search

HNRNPH1

0.88	Heterogeneous nuclear ribonucleoprotein H

0.52	GO:0043484	regulation of RNA splicing
0.37	GO:0008380	RNA splicing
0.37	GO:0006397	mRNA processing
0.36	GO:0071495	cellular response to endogenous stimulus
0.36	GO:0071310	cellular response to organic substance
0.35	GO:0071774	response to fibroblast growth factor
0.35	GO:1901652	response to peptide
0.35	GO:1901699	cellular response to nitrogen compound
0.35	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.35	GO:1901701	cellular response to oxygen-containing compound

0.59	GO:0003723	RNA binding
0.36	GO:0005515	protein binding

0.58	GO:0019013	viral nucleocapsid
0.55	GO:0030529	intracellular ribonucleoprotein complex
0.49	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol
0.43	GO:1902494	catalytic complex
0.30	GO:0016020	membrane

sp|O35738|KLF12_MOUSE
Krueppel-like factor 12
Search

KLF12

0.97	Kruppel like factor 12

0.56	GO:0000122	negative regulation of transcription by RNA polymerase II
0.39	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.47	GO:0003700	DNA binding transcription factor activity
0.36	GO:0003714	transcription corepressor activity
0.36	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding

0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|O35739|KLF9_MOUSE
Krueppel-like factor 9
Search

KLF9

0.95	Kruppel like factor 9

0.64	GO:0071387	cellular response to cortisol stimulus
0.61	GO:0097067	cellular response to thyroid hormone stimulus
0.61	GO:0010839	negative regulation of keratinocyte proliferation
0.56	GO:0007623	circadian rhythm
0.43	GO:1902070	positive regulation of sphingolipid mediated signaling pathway
0.42	GO:0006357	regulation of transcription by RNA polymerase II
0.41	GO:0045893	positive regulation of transcription, DNA-templated
0.38	GO:0050847	progesterone receptor signaling pathway
0.38	GO:0006366	transcription by RNA polymerase II
0.38	GO:0007566	embryo implantation

0.51	GO:0003676	nucleic acid binding
0.40	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.39	GO:0003682	chromatin binding
0.35	GO:0046872	metal ion binding
0.33	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding

0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane
0.34	GO:0005925	focal adhesion
0.30	GO:0031224	intrinsic component of membrane

sp|O35740|CITE2_MOUSE
Cbp/p300-interacting transactivator 2
Search

CITED2

0.97	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2

0.65	GO:0035801	adrenal cortex development
0.63	GO:0038107	nodal signaling pathway involved in determination of left/right asymmetry
0.63	GO:2000020	positive regulation of male gonad development
0.62	GO:0060971	embryonic heart tube left/right pattern formation
0.61	GO:0003140	determination of left/right asymmetry in lateral mesoderm
0.61	GO:0070986	left/right axis specification
0.61	GO:0061156	pulmonary artery morphogenesis
0.61	GO:0001570	vasculogenesis
0.60	GO:0061308	cardiac neural crest cell development involved in heart development
0.60	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus

0.62	GO:0001105	RNA polymerase II transcription coactivator activity
0.60	GO:0046332	SMAD binding
0.58	GO:0001102	RNA polymerase II activating transcription factor binding
0.57	GO:0003682	chromatin binding
0.50	GO:0050693	LBD domain binding
0.46	GO:0003700	DNA binding transcription factor activity
0.45	GO:0003714	transcription corepressor activity
0.43	GO:0035035	histone acetyltransferase binding
0.43	GO:0008022	protein C-terminus binding
0.42	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding

0.61	GO:0005634	nucleus
0.52	GO:0000785	chromatin
0.49	GO:0070013	intracellular organelle lumen
0.39	GO:0005829	cytosol
0.37	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.33

GO:0032041

sp|O35744|CHIL3_MOUSE
Chitinase-like protein 3
Search

CHIA

0.83	Acidic mammalian chitinase

0.73	GO:0006030	chitin metabolic process
0.60	GO:0005975	carbohydrate metabolic process
0.57	GO:1901072	glucosamine-containing compound catabolic process
0.53	GO:0006026	aminoglycan catabolic process
0.52	GO:0090197	positive regulation of chemokine secretion
0.52	GO:0002532	production of molecular mediator involved in inflammatory response
0.51	GO:0042737	drug catabolic process
0.38	GO:0006915	apoptotic process
0.38	GO:0044245	polysaccharide digestion
0.38	GO:0002376	immune system process

0.76	GO:0008061	chitin binding
0.65	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.47	GO:0019900	kinase binding
0.35	GO:0030246	carbohydrate binding
0.34	GO:0061783	peptidoglycan muralytic activity

0.63	GO:0005576	extracellular region
0.38	GO:0005737	cytoplasm
0.36	GO:0097708	intracellular vesicle
0.35	GO:0005635	nuclear envelope
0.35	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

0.65

EC:3.2.1

GO:0004553

sp|O35841|API5_MOUSE
Apoptosis inhibitor 5
Search

API5

0.95	Apoptosis inhibitor 5

0.84	GO:2000270	negative regulation of fibroblast apoptotic process
0.50	GO:0006915	apoptotic process
0.34	GO:0099643	signal release from synapse
0.34	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.33	GO:0006836	neurotransmitter transport
0.33	GO:0001505	regulation of neurotransmitter levels
0.33	GO:0051649	establishment of localization in cell

0.85	GO:0017134	fibroblast growth factor binding
0.38	GO:0003723	RNA binding
0.34	GO:0016874	ligase activity

0.77	GO:0016607	nuclear speck
0.70	GO:0005681	spliceosomal complex
0.37	GO:0005737	cytoplasm
0.33	GO:0098793	presynapse
0.33	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

0.34

GO:0016874

sp|O35855|BCAT2_MOUSE
Branched-chain-amino-acid aminotransferase, mitochondrial
Search

BCAT2

0.50	Branched-chain-amino-acid aminotransferase

0.70	GO:0009081	branched-chain amino acid metabolic process
0.61	GO:0008652	cellular amino acid biosynthetic process
0.52	GO:1990830	cellular response to leukemia inhibitory factor
0.48	GO:0010817	regulation of hormone levels
0.46	GO:0009063	cellular amino acid catabolic process
0.45	GO:1901605	alpha-amino acid metabolic process
0.36	GO:0007595	lactation
0.34	GO:0055114	oxidation-reduction process
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0006706	steroid catabolic process

0.78	GO:0004084	branched-chain-amino-acid transaminase activity
0.34	GO:0016491	oxidoreductase activity
0.34	GO:0042802	identical protein binding
0.33	GO:0019843	rRNA binding
0.33	GO:0003735	structural constituent of ribosome

0.44	GO:0005739	mitochondrion
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.33	GO:0005840	ribosome
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.78

EC:2.6.1.42

GO:0004084

sp|O35857|TIM44_MOUSE
Mitochondrial import inner membrane translocase subunit TIM44
Search

TIMM44

0.78	Mitochondrial import inner membrane translocase subunit TIM44

0.80	GO:0030150	protein import into mitochondrial matrix
0.36	GO:1905242	response to 3,3',5-triiodo-L-thyronine
0.35	GO:0055007	cardiac muscle cell differentiation

0.76	GO:0051087	chaperone binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0031966	mitochondrial membrane
0.56	GO:0019866	organelle inner membrane
0.50	GO:0005759	mitochondrial matrix

sp|O35864|CSN5_MOUSE
COP9 signalosome complex subunit 5
Search

COPS5

0.85	COP9 constitutive photomorphogenic homolog subunit 5

0.58	GO:1990182	exosomal secretion
0.58	GO:1903894	regulation of IRE1-mediated unfolded protein response
0.58	GO:0006508	proteolysis
0.55	GO:0051091	positive regulation of DNA binding transcription factor activity
0.54	GO:0046328	regulation of JNK cascade
0.53	GO:0043066	negative regulation of apoptotic process
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.50	GO:0051726	regulation of cell cycle
0.49	GO:0070647	protein modification by small protein conjugation or removal
0.36	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c

0.66	GO:0004222	metalloendopeptidase activity
0.60	GO:0035718	macrophage migration inhibitory factor binding
0.52	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.49	GO:0019899	enzyme binding
0.36	GO:0003713	transcription coactivator activity
0.35	GO:0019784	NEDD8-specific protease activity
0.35	GO:0046872	metal ion binding
0.35	GO:0046983	protein dimerization activity
0.34	GO:0003743	translation initiation factor activity

0.76	GO:0008180	COP9 signalosome
0.55	GO:0008021	synaptic vesicle
0.49	GO:0000785	chromatin
0.48	GO:0005829	cytosol
0.48	GO:0005654	nucleoplasm
0.40	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0030054	cell junction
0.34	GO:0005852	eukaryotic translation initiation factor 3 complex
0.34	GO:0005667	transcription factor complex
0.33	GO:0005739	mitochondrion

0.66

GO:0004222

sp|O35874|SATT_MOUSE
Neutral amino acid transporter A
Search

SLC1A4

0.45	Neutral amino acid transporter A

0.61	GO:0034589	hydroxyproline transport
0.59	GO:0015811	L-cystine transport
0.59	GO:0015808	L-alanine transport
0.58	GO:0015825	L-serine transport
0.55	GO:0015826	threonine transport
0.55	GO:0055085	transmembrane transport
0.55	GO:0050890	cognition
0.54	GO:0015824	proline transport
0.52	GO:0006821	chloride transport
0.37	GO:0006868	glutamine transport

0.72	GO:0015293	symporter activity
0.61	GO:0034590	L-hydroxyproline transmembrane transporter activity
0.59	GO:0015184	L-cystine transmembrane transporter activity
0.59	GO:0015180	L-alanine transmembrane transporter activity
0.59	GO:0015194	L-serine transmembrane transporter activity
0.58	GO:0015195	L-threonine transmembrane transporter activity
0.55	GO:0015193	L-proline transmembrane transporter activity
0.53	GO:0005254	chloride channel activity
0.37	GO:0015186	L-glutamine transmembrane transporter activity
0.34	GO:0104005	hijacked molecular function

0.53	GO:0005882	intermediate filament
0.53	GO:0005813	centrosome
0.40	GO:0042470	melanosome
0.39	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite
0.37	GO:0070062	extracellular exosome
0.36	GO:0009986	cell surface
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|O35885|ASCL2_MOUSE
Achaete-scute homolog 2
Search

ASCL2

0.97	Achaete-scute like protein 2

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.68	GO:0060712	spongiotrophoblast layer development
0.64	GO:0060706	cell differentiation involved in embryonic placenta development
0.64	GO:0001666	response to hypoxia
0.63	GO:0035019	somatic stem cell population maintenance
0.57	GO:0045892	negative regulation of transcription, DNA-templated
0.54	GO:0050767	regulation of neurogenesis
0.48	GO:0006351	transcription, DNA-templated
0.47	GO:0051961	negative regulation of nervous system development
0.47	GO:0010721	negative regulation of cell development

0.68	GO:0046983	protein dimerization activity
0.67	GO:0070888	E-box binding
0.65	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.51	GO:0090575	RNA polymerase II transcription factor complex
0.42	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|O35887|CALU_MOUSE
Calumenin
Search

CALU

0.94	Calumenin-B

0.35	GO:0014012	peripheral nervous system axon regeneration
0.35	GO:0043687	post-translational protein modification
0.34	GO:0014070	response to organic cyclic compound
0.34	GO:0043086	negative regulation of catalytic activity

0.70	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.34	GO:0004857	enzyme inhibitor activity

0.51	GO:0005783	endoplasmic reticulum
0.46	GO:0042470	melanosome
0.46	GO:0016528	sarcoplasm
0.42	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.42	GO:0005794	Golgi apparatus
0.41	GO:0031984	organelle subcompartment
0.41	GO:0043233	organelle lumen
0.41	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|O35892|SP100_MOUSE
Nuclear autoantigen Sp-100
Search

SP100

0.92	Nuclear autoantigen Sp-100

0.68	GO:1902044	regulation of Fas signaling pathway
0.66	GO:0046826	negative regulation of protein export from nucleus
0.63	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.63	GO:0010596	negative regulation of endothelial cell migration
0.60	GO:0045765	regulation of angiogenesis
0.58	GO:0000723	telomere maintenance
0.46	GO:0006351	transcription, DNA-templated
0.46	GO:2001141	regulation of RNA biosynthetic process
0.46	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:0010468	regulation of gene expression

0.51	GO:0003677	DNA binding
0.44	GO:0005515	protein binding
0.37	GO:0046872	metal ion binding

0.62	GO:0016605	PML body
0.61	GO:0030870	Mre11 complex
0.41	GO:0005737	cytoplasm

sp|O35900|LSM2_MOUSE
U6 snRNA-associated Sm-like protein LSm2
Search

LSM2

0.80	U6 snRNA-associated Sm-like protein LSm2

0.70	GO:0000398	mRNA splicing, via spliceosome
0.37	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.37	GO:0006438	valyl-tRNA aminoacylation
0.36	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.36	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.35	GO:0006402	mRNA catabolic process
0.34	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.34	GO:0046856	phosphatidylinositol dephosphorylation
0.34	GO:0022618	ribonucleoprotein complex assembly

0.56	GO:0003723	RNA binding
0.52	GO:0017160	Ral GTPase binding
0.38	GO:0000213	tRNA-intron endonuclease activity
0.37	GO:0004832	valine-tRNA ligase activity
0.37	GO:0019901	protein kinase binding
0.36	GO:0002161	aminoacyl-tRNA editing activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.78	GO:0005688	U6 snRNP
0.76	GO:0000932	P-body
0.75	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.71	GO:0005681	spliceosomal complex
0.48	GO:1990726	Lsm1-7-Pat1 complex
0.44	GO:1902494	catalytic complex
0.33	GO:0019013	viral nucleocapsid
0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.33	GO:0031966	mitochondrial membrane

0.38	EC:3.1.27.9	GO:0000213
0.37	KEGG:R03665	GO:0004832

sp|O35902|DSG3_MOUSE
Desmoglein-3
Search

0.96	LOW QUALITY PROTEIN: desmoglein-4

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.56	GO:0030216	keratinocyte differentiation
0.56	GO:0001942	hair follicle development
0.55	GO:0030509	BMP signaling pathway
0.39	GO:0050821	protein stabilization
0.38	GO:0003165	Purkinje myocyte development
0.37	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication
0.37	GO:0012501	programmed cell death
0.37	GO:0098911	regulation of ventricular cardiac muscle cell action potential
0.37	GO:0002934	desmosome organization

0.70	GO:0005509	calcium ion binding
0.41	GO:0045295	gamma-catenin binding
0.36	GO:0050839	cell adhesion molecule binding

0.59	GO:0030057	desmosome
0.55	GO:0005886	plasma membrane
0.41	GO:0070062	extracellular exosome
0.39	GO:0005914	spot adherens junction
0.38	GO:0098562	cytoplasmic side of membrane
0.37	GO:0014704	intercalated disc
0.35	GO:0005829	cytosol
0.33	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0045177	apical part of cell
0.31	GO:0031012	extracellular matrix

sp|O35903|CCL25_MOUSE
C-C motif chemokine 25
Search

CCL25

0.97	C-C motif chemokine ligand 25

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.65	GO:1903237	negative regulation of leukocyte tethering or rolling
0.62	GO:0001954	positive regulation of cell-matrix adhesion
0.59	GO:0071674	mononuclear cell migration
0.59	GO:0072676	lymphocyte migration
0.58	GO:1990266	neutrophil migration
0.57	GO:0071347	cellular response to interleukin-1
0.56	GO:0071356	cellular response to tumor necrosis factor
0.56	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.84	GO:0008009	chemokine activity
0.66	GO:0048020	CCR chemokine receptor binding
0.38	GO:0005179	hormone activity

0.66	GO:0005576	extracellular region
0.33	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|O35904|PK3CD_MOUSE
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Search

PIK3CD

0.95	Phosphatidylinositol 3-kinase catalytic delta polypeptide

0.82	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process
0.80	GO:0048015	phosphatidylinositol-mediated signaling
0.74	GO:0046854	phosphatidylinositol phosphorylation
0.61	GO:0033031	positive regulation of neutrophil apoptotic process
0.55	GO:0030335	positive regulation of cell migration
0.51	GO:0010628	positive regulation of gene expression
0.47	GO:0030168	platelet activation
0.46	GO:0002250	adaptive immune response
0.46	GO:0060326	cell chemotaxis
0.46	GO:0048696	regulation of collateral sprouting in absence of injury

0.83	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.49	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.49	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity
0.35	GO:0005515	protein binding
0.34	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0003700	DNA binding transcription factor activity

0.46	GO:0005942	phosphatidylinositol 3-kinase complex
0.45	GO:0005622	intracellular
0.38	GO:0005886	plasma membrane
0.35	GO:0030496	midbody
0.34	GO:0043227	membrane-bounded organelle
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0043228	non-membrane-bounded organelle
0.33	GO:0044422	organelle part
0.30	GO:0016021	integral component of membrane

0.83	EC:2.7.1.137	GO:0016303
0.83	KEGG:R03362	GO:0016303

sp|O35906|SPIB_MOUSE
Transcription factor Spi-B
Search

0.93	Transcription factor Spi-B

0.61	GO:0030225	macrophage differentiation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0030851	granulocyte differentiation
0.51	GO:0045646	regulation of erythrocyte differentiation
0.50	GO:0044027	hypermethylation of CpG island
0.50	GO:0030218	erythrocyte differentiation
0.49	GO:0045347	negative regulation of MHC class II biosynthetic process
0.49	GO:0090241	negative regulation of histone H4 acetylation

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.49	GO:0035326	enhancer binding
0.49	GO:0051525	NFAT protein binding
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0001047	core promoter binding
0.46	GO:0001085	RNA polymerase II transcription factor binding
0.45	GO:0003690	double-stranded DNA binding
0.33	GO:0003723	RNA binding
0.33	GO:0008408	3'-5' exonuclease activity

0.61	GO:0005634	nucleus
0.43	GO:0000785	chromatin
0.42	GO:0031974	membrane-enclosed lumen
0.36	GO:0005667	transcription factor complex
0.32	GO:0005737	cytoplasm

0.33

GO:0003887

sp|O35912|EMP3_MOUSE
Epithelial membrane protein 3
Search

EMP3

0.95	Epithelial membrane protein 3

0.70	GO:0016049	cell growth
0.65	GO:0032060	bleb assembly
0.57	GO:0008219	cell death
0.38	GO:0008285	negative regulation of cell proliferation
0.38	GO:0042552	myelination
0.38	GO:0007050	cell cycle arrest
0.37	GO:0010977	negative regulation of neuron projection development
0.35	GO:0007422	peripheral nervous system development
0.35	GO:0010927	cellular component assembly involved in morphogenesis
0.34	GO:0007268	chemical synaptic transmission

0.34

GO:0005515

protein binding

0.45	GO:0005886	plasma membrane
0.38	GO:0043218	compact myelin
0.37	GO:0005923	bicellular tight junction
0.30	GO:0016021	integral component of membrane

sp|O35914|BNC1_MOUSE
Zinc finger protein basonuclin-1
Search

BNC1

0.96	Zinc finger protein basonuclin-1

0.41	GO:0007283	spermatogenesis
0.41	GO:0008284	positive regulation of cell proliferation
0.40	GO:0032502	developmental process
0.39	GO:0006356	regulation of transcription by RNA polymerase I
0.38	GO:0050678	regulation of epithelial cell proliferation
0.38	GO:0042060	wound healing
0.37	GO:0040007	growth
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0051276	chromosome organization

0.51	GO:0003676	nucleic acid binding
0.36	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding
0.35	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005654	nucleoplasm
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|O35926|CD5R2_MOUSE
Cyclin-dependent kinase 5 activator 2
Search

CDK5R2

0.89	Cyclin-dependent kinase 5 activator

0.80	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.66	GO:0021722	superior olivary nucleus maturation
0.63	GO:0021819	layer formation in cerebral cortex
0.61	GO:0021766	hippocampus development
0.60	GO:0021549	cerebellum development
0.60	GO:0001764	neuron migration
0.57	GO:0051050	positive regulation of transport
0.54	GO:0017158	regulation of calcium ion-dependent exocytosis
0.52	GO:0042501	serine phosphorylation of STAT protein
0.51	GO:0007158	neuron cell-cell adhesion

0.86	GO:0016534	cyclin-dependent protein kinase 5 activator activity
0.50	GO:0035255	ionotropic glutamate receptor binding
0.49	GO:0016301	kinase activity
0.48	GO:0002020	protease binding
0.46	GO:0019901	protein kinase binding
0.46	GO:0051015	actin filament binding
0.38	GO:0045296	cadherin binding
0.38	GO:0046875	ephrin receptor binding
0.37	GO:0008289	lipid binding
0.36	GO:0005509	calcium ion binding

0.86	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex
0.47	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005654	nucleoplasm
0.38	GO:0043197	dendritic spine
0.38	GO:0031594	neuromuscular junction
0.38	GO:0030426	growth cone
0.38	GO:0014069	postsynaptic density
0.38	GO:0043025	neuronal cell body
0.38	GO:0043292	contractile fiber
0.38	GO:0030424	axon

0.32

GO:0016773

sp|O35927|CTND2_MOUSE
Catenin delta-2
Search

0.91	T-cell delta-catenin

0.77	GO:0098609	cell-cell adhesion
0.57	GO:0060997	dendritic spine morphogenesis
0.53	GO:0060828	regulation of canonical Wnt signaling pathway
0.44	GO:0001764	neuron migration
0.37	GO:0007612	learning
0.37	GO:0048167	regulation of synaptic plasticity
0.37	GO:0001763	morphogenesis of a branching structure
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.54

GO:0008013

beta-catenin binding

0.55	GO:0043204	perikaryon
0.37	GO:0030425	dendrite
0.37	GO:0005912	adherens junction
0.37	GO:0014069	postsynaptic density
0.34	GO:0005634	nucleus
0.31	GO:0005737	cytoplasm

sp|O35929|REM1_MOUSE
GTP-binding protein REM 1
Search

REM1

0.78	GTP-binding protein GEM

0.84	GO:1901842	negative regulation of high voltage-gated calcium channel activity
0.61	GO:0007165	signal transduction
0.43	GO:0051310	metaphase plate congression
0.41	GO:0000278	mitotic cell cycle
0.39	GO:0051276	chromosome organization
0.35	GO:0006955	immune response

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0000287	magnesium ion binding
0.37	GO:0005246	calcium channel regulator activity
0.35	GO:0005516	calmodulin binding

0.43	GO:0051233	spindle midzone
0.43	GO:0030496	midbody
0.42	GO:0072686	mitotic spindle
0.41	GO:0009898	cytoplasmic side of plasma membrane
0.38	GO:0005634	nucleus

sp|O35930|GP1BA_MOUSE
Platelet glycoprotein Ib alpha chain
Search

GP1BA

0.84	Glycoprotein Ib platelet alpha subunit

0.68	GO:0042730	fibrinolysis
0.64	GO:0007596	blood coagulation
0.58	GO:0046426	negative regulation of JAK-STAT cascade
0.57	GO:0007155	cell adhesion
0.56	GO:0000902	cell morphogenesis
0.55	GO:0006469	negative regulation of protein kinase activity
0.54	GO:0019221	cytokine-mediated signaling pathway
0.41	GO:0001775	cell activation
0.38	GO:0045652	regulation of megakaryocyte differentiation
0.38	GO:0070493	thrombin-activated receptor signaling pathway

0.56	GO:0004860	protein kinase inhibitor activity
0.38	GO:0015057	thrombin-activated receptor activity
0.35	GO:0005515	protein binding
0.35	GO:0005509	calcium ion binding
0.33	GO:0003677	DNA binding
0.33	GO:0008144	drug binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0005230	extracellular ligand-gated ion channel activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.67	GO:0031362	anchored component of external side of plasma membrane
0.42	GO:0005887	integral component of plasma membrane
0.41	GO:0070062	extracellular exosome
0.39	GO:0005737	cytoplasm
0.35	GO:0070701	mucus layer
0.34	GO:0016604	nuclear body
0.33	GO:0012505	endomembrane system
0.33	GO:0043234	protein complex

0.32

EC:3.2.1

GO:0004553

sp|O35936|ALOX8_MOUSE
Arachidonate 8S-lipoxygenase
Search

0.91	Epidermis-type lipoxygenase 3

0.67	GO:0019372	lipoxygenase pathway
0.67	GO:0043651	linoleic acid metabolic process
0.65	GO:0019369	arachidonic acid metabolic process
0.61	GO:0051047	positive regulation of secretion
0.58	GO:0051240	positive regulation of multicellular organismal process
0.58	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway
0.58	GO:0010744	positive regulation of macrophage derived foam cell differentiation
0.58	GO:0090196	regulation of chemokine secretion
0.56	GO:0045606	positive regulation of epidermal cell differentiation
0.56	GO:0045616	regulation of keratinocyte differentiation

0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.62	GO:0005506	iron ion binding
0.48	GO:0005509	calcium ion binding
0.39	GO:0016853	isomerase activity
0.39	GO:0008289	lipid binding
0.34	GO:0005515	protein binding

0.51	GO:0019898	extrinsic component of membrane
0.49	GO:0005829	cytosol
0.48	GO:0005856	cytoskeleton
0.42	GO:0005886	plasma membrane
0.40	GO:0005641	nuclear envelope lumen
0.39	GO:0016363	nuclear matrix
0.39	GO:0070062	extracellular exosome
0.38	GO:0031965	nuclear membrane
0.37	GO:0005654	nucleoplasm

0.75

EC:1.13.11

GO:0016702

sp|O35942|NEK2_MOUSE
Serine/threonine-protein kinase Nek2
Search

NEK2

0.95	Serine/threonine-protein kinase Nek2

0.63	GO:1903126	negative regulation of centriole-centriole cohesion
0.63	GO:0006468	protein phosphorylation
0.61	GO:0046602	regulation of mitotic centrosome separation
0.60	GO:1904355	positive regulation of telomere capping
0.60	GO:0051299	centrosome separation
0.59	GO:0051973	positive regulation of telomerase activity
0.59	GO:0051988	regulation of attachment of spindle microtubules to kinetochore
0.59	GO:0032212	positive regulation of telomere maintenance via telomerase
0.57	GO:0043392	negative regulation of DNA binding
0.56	GO:0090307	mitotic spindle assembly

0.64	GO:0004672	protein kinase activity
0.57	GO:0019903	protein phosphatase binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046872	metal ion binding
0.33	GO:0001222	transcription corepressor binding
0.33	GO:0019894	kinesin binding
0.33	GO:0033613	activating transcription factor binding

0.55	GO:0030496	midbody
0.55	GO:0005813	centrosome
0.54	GO:0000776	kinetochore
0.54	GO:0000922	spindle pole
0.53	GO:0000794	condensed nuclear chromosome
0.50	GO:0005654	nucleoplasm
0.37	GO:0000779	condensed chromosome, centromeric region
0.36	GO:0005730	nucleolus
0.36	GO:0005874	microtubule
0.34	GO:0005829	cytosol

sp|O35943|FRDA_MOUSE
Frataxin, mitochondrial
Search

FXN

0.89	Frataxin, mitochondrial

0.74	GO:0016226	iron-sulfur cluster assembly
0.61	GO:0010722	regulation of ferrochelatase activity
0.60	GO:1904229	regulation of succinate dehydrogenase activity
0.60	GO:1904234	positive regulation of aconitate hydratase activity
0.60	GO:0018282	metal incorporation into metallo-sulfur cluster
0.58	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.56	GO:0019230	proprioception
0.56	GO:0010039	response to iron ion
0.56	GO:0051353	positive regulation of oxidoreductase activity
0.56	GO:0070301	cellular response to hydrogen peroxide

0.80	GO:0004322	ferroxidase activity
0.76	GO:0008199	ferric iron binding
0.60	GO:0034986	iron chaperone activity
0.53	GO:0008198	ferrous iron binding
0.50	GO:0051537	2 iron, 2 sulfur cluster binding
0.37	GO:0016307	phosphatidylinositol phosphate kinase activity
0.35	GO:0005515	protein binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding

0.60	GO:0005739	mitochondrion
0.48	GO:0005829	cytosol
0.35	GO:0005923	bicellular tight junction
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0070062	extracellular exosome
0.32	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane

0.80

EC:1.16.3.1

GO:0004322

sp|O35945|AL1A7_MOUSE
Aldehyde dehydrogenase, cytosolic 1
Search

ALDH1A1

0.80	Retinal dehydrogenase 1

0.53	GO:0055114	oxidation-reduction process
0.52	GO:0042572	retinol metabolic process
0.43	GO:0042904	9-cis-retinoic acid biosynthetic process
0.43	GO:0002072	optic cup morphogenesis involved in camera-type eye development
0.40	GO:0043065	positive regulation of apoptotic process
0.38	GO:0042493	response to drug
0.38	GO:0061624	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
0.38	GO:0044849	estrous cycle
0.37	GO:0007494	midgut development
0.37	GO:0032355	response to estradiol

0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.41	GO:0051287	NAD binding
0.38	GO:0005497	androgen binding
0.36	GO:0005096	GTPase activator activity
0.36	GO:0042802	identical protein binding

0.47	GO:0005829	cytosol
0.39	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus

0.69

EC:1.2.1

GO:0016620

sp|O35949|ELOV3_MOUSE
Elongation of very long chain fatty acids protein 3
Search

ELOVL3

0.55	Elongation of very long chain fatty acids protein 3

0.78	GO:0019367	fatty acid elongation, saturated fatty acid
0.77	GO:0042761	very long-chain fatty acid biosynthetic process
0.70	GO:0034625	fatty acid elongation, monounsaturated fatty acid
0.68	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.65	GO:0006636	unsaturated fatty acid biosynthetic process
0.64	GO:0034626	fatty acid elongation, polyunsaturated fatty acid
0.50	GO:0030148	sphingolipid biosynthetic process
0.48	GO:0042759	long-chain fatty acid biosynthetic process
0.36	GO:0036109	alpha-linolenic acid metabolic process
0.35	GO:0043651	linoleic acid metabolic process

0.82	GO:0102756	very-long-chain 3-ketoacyl-CoA synthase activity
0.82	GO:0102338	3-oxo-lignoceronyl-CoA synthase activity
0.82	GO:0102336	3-oxo-arachidoyl-CoA synthase activity
0.82	GO:0102337	3-oxo-cerotoyl-CoA synthase activity
0.78	GO:0009922	fatty acid elongase activity
0.34	GO:0005515	protein binding

0.64	GO:0005783	endoplasmic reticulum
0.59	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.56	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.82

EC:2.3.1.199

GO:0102338

sp|O35954|PITM1_MOUSE
Membrane-associated phosphatidylinositol transfer protein 1
Search

PITPNM1

0.94	Membrane-associated phosphatidylinositol transfer protein 1

0.78	GO:0015914	phospholipid transport
0.42	GO:0048015	phosphatidylinositol-mediated signaling
0.37	GO:0015031	protein transport
0.36	GO:0007420	brain development
0.36	GO:0007602	phototransduction
0.36	GO:0006661	phosphatidylinositol biosynthetic process

0.79	GO:0005548	phospholipid transporter activity
0.61	GO:0030971	receptor tyrosine kinase binding
0.60	GO:0031210	phosphatidylcholine binding
0.60	GO:0070300	phosphatidic acid binding
0.54	GO:0035091	phosphatidylinositol binding
0.53	GO:0046872	metal ion binding

0.56	GO:0036464	cytoplasmic ribonucleoprotein granule
0.54	GO:0005815	microtubule organizing center
0.50	GO:0005829	cytosol
0.42	GO:0044297	cell body
0.41	GO:0032154	cleavage furrow
0.40	GO:0030496	midbody
0.40	GO:0005811	lipid droplet
0.40	GO:0032580	Golgi cisterna membrane
0.38	GO:0005789	endoplasmic reticulum membrane

sp|O35955|PSB10_MOUSE
Proteasome subunit beta type-10
Search

PSMB10

0.53	Proteasome subunit beta type

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.61	GO:0002376	immune system process
0.54	GO:0032943	mononuclear cell proliferation
0.51	GO:0001775	cell activation
0.49	GO:0000902	cell morphogenesis
0.38	GO:0043632	modification-dependent macromolecule catabolic process
0.36	GO:1903955	positive regulation of protein targeting to mitochondrion
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0038095	Fc-epsilon receptor signaling pathway

0.77	GO:0004298	threonine-type endopeptidase activity
0.33	GO:0005515	protein binding

0.76	GO:0005839	proteasome core complex
0.60	GO:0005634	nucleus
0.57	GO:1990111	spermatoproteasome complex
0.48	GO:0005737	cytoplasm
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.77

EC:3.4.25

GO:0004298

sp|O35963|RB33B_MOUSE
Ras-related protein Rab-33B
Search

RAB33B

0.95	Putative rab subfamily protein of small gtpase (Fragment)

0.60	GO:1903434	negative regulation of constitutive secretory pathway
0.59	GO:2000156	regulation of retrograde vesicle-mediated transport, Golgi to ER
0.58	GO:1903358	regulation of Golgi organization
0.57	GO:0000042	protein targeting to Golgi
0.54	GO:0048705	skeletal system morphogenesis
0.53	GO:0000045	autophagosome assembly
0.53	GO:2000785	regulation of autophagosome assembly
0.45	GO:0019882	antigen processing and presentation
0.37	GO:0050678	regulation of epithelial cell proliferation
0.36	GO:0001558	regulation of cell growth

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity

0.57	GO:0005796	Golgi lumen
0.38	GO:0000139	Golgi membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005886	plasma membrane

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

sp|O35969|GAMT_MOUSE
Guanidinoacetate N-methyltransferase
Search

GAMT

0.97	Guanidinoacetate N-methyltransferase A

0.77	GO:0006601	creatine biosynthetic process
0.61	GO:0032259	methylation
0.53	GO:0040014	regulation of multicellular organism growth
0.51	GO:0007283	spermatogenesis
0.50	GO:0009887	animal organ morphogenesis
0.45	GO:0046498	S-adenosylhomocysteine metabolic process
0.45	GO:0046500	S-adenosylmethionine metabolic process
0.36	GO:1990402	embryonic liver development
0.35	GO:0006936	muscle contraction

0.85	GO:0030731	guanidinoacetate N-methyltransferase activity
0.35	GO:0042803	protein homodimerization activity

0.40	GO:0005634	nucleus
0.37	GO:0070062	extracellular exosome
0.36	GO:0005737	cytoplasm
0.36	GO:0005902	microvillus
0.30	GO:0016020	membrane

0.85	EC:2.1.1.2	GO:0030731
0.85	KEGG:R01883	GO:0030731

sp|O35972|RM23_MOUSE
39S ribosomal protein L23, mitochondrial
Search

MRPL23

0.96	Mitochondrial ribosomal protein L23

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.38	GO:0006942	regulation of striated muscle contraction
0.34	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.39	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.45	GO:0005759	mitochondrial matrix
0.39	GO:0001650	fibrillar center
0.37	GO:0005861	troponin complex
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane

sp|O35973|PER1_MOUSE
Period circadian protein homolog 1
Search

PER1

0.89	Period circadian protein like protein 1

0.85	GO:0097167	circadian regulation of translation
0.85	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway
0.83	GO:0043153	entrainment of circadian clock by photoperiod
0.83	GO:0042634	regulation of hair cycle
0.81	GO:0032922	circadian regulation of gene expression
0.80	GO:0002028	regulation of sodium ion transport
0.80	GO:0051591	response to cAMP
0.79	GO:0043966	histone H3 acetylation
0.78	GO:0043967	histone H4 acetylation
0.77	GO:0070932	histone H3 deacetylation

0.82	GO:0070888	E-box binding
0.79	GO:0031490	chromatin DNA binding
0.74	GO:0031625	ubiquitin protein ligase binding
0.73	GO:0019900	kinase binding
0.70	GO:0000989	transcription factor activity, transcription factor binding
0.68	GO:0008134	transcription factor binding

0.65	GO:0005654	nucleoplasm
0.64	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|O35975|NAR2B_MOUSE
T-cell ecto-ADP-ribosyltransferase 2
Search

0.68	T-cell ecto-ADP-ribosyltransferase 2

0.84	GO:0006471	protein ADP-ribosylation
0.52	GO:0019677	NAD catabolic process
0.45	GO:0018195	peptidyl-arginine modification

0.85	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity
0.52	GO:0061810	NAD glycohydrolase activity

0.47	GO:0046658	anchored component of plasma membrane
0.47	GO:0031233	intrinsic component of external side of plasma membrane
0.39	GO:0019897	extrinsic component of plasma membrane
0.30	GO:0016021	integral component of membrane

0.85

EC:2.4.2.31

GO:0003956

sp|O35980|NTH_MOUSE
Endonuclease III-like protein 1
Search

NTHL1

0.97	Nth like DNA glycosylase 1

0.82	GO:0006285	base-excision repair, AP site formation
0.60	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion
0.36	GO:0009223	pyrimidine deoxyribonucleotide catabolic process
0.34	GO:0006304	DNA modification
0.33	GO:0035556	intracellular signal transduction

0.75	GO:0000703	oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
0.74	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity
0.64	GO:0051539	4 iron, 4 sulfur cluster binding
0.57	GO:0004519	endonuclease activity
0.55	GO:0003677	DNA binding
0.49	GO:0046872	metal ion binding
0.35	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity
0.33	GO:0005515	protein binding

0.59	GO:0005634	nucleus
0.55	GO:0005739	mitochondrion
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.74

EC:4.2.99.18

GO:0003906

sp|O35984|PBX2_MOUSE
Pre-B-cell leukemia transcription factor 2
Search

PBX2

0.91	Pre-B-cell leukemia transcription factor 2

0.58	GO:0009954	proximal/distal pattern formation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0030326	embryonic limb morphogenesis
0.56	GO:0010468	regulation of gene expression
0.53	GO:0051254	positive regulation of RNA metabolic process
0.53	GO:0010557	positive regulation of macromolecule biosynthetic process
0.53	GO:0031328	positive regulation of cellular biosynthetic process
0.45	GO:0007399	nervous system development
0.45	GO:0006366	transcription by RNA polymerase II

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.50	GO:0003682	chromatin binding
0.48	GO:0008134	transcription factor binding
0.42	GO:0035326	enhancer binding
0.41	GO:0046982	protein heterodimerization activity
0.34	GO:0005509	calcium ion binding
0.34	GO:0004872	receptor activity

0.61	GO:0005634	nucleus
0.55	GO:0005667	transcription factor complex
0.40	GO:0043233	organelle lumen
0.38	GO:0044446	intracellular organelle part
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|O35988|SDC4_MOUSE
Syndecan-4
Search

SDC4

0.80

Syndecan

0.60	GO:1903553	positive regulation of extracellular exosome assembly
0.58	GO:1903543	positive regulation of exosomal secretion
0.58	GO:0042060	wound healing
0.58	GO:0010762	regulation of fibroblast migration
0.57	GO:0002009	morphogenesis of an epithelium
0.57	GO:0060122	inner ear receptor cell stereocilium organization
0.57	GO:0042130	negative regulation of T cell proliferation
0.56	GO:0060606	tube closure
0.55	GO:0021915	neural tube development
0.54	GO:0048598	embryonic morphogenesis

0.60	GO:0070053	thrombospondin receptor activity
0.53	GO:0042802	identical protein binding
0.42	GO:0030165	PDZ domain binding
0.41	GO:0005080	protein kinase C binding
0.40	GO:0001968	fibronectin binding
0.37	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.35	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.35	GO:0043395	heparan sulfate proteoglycan binding
0.34	GO:0046983	protein dimerization activity
0.33	GO:0030554	adenyl nucleotide binding

0.53	GO:0009986	cell surface
0.41	GO:0005925	focal adhesion
0.40	GO:0043034	costamere
0.40	GO:0005576	extracellular region
0.39	GO:0098857	membrane microdomain
0.38	GO:0005796	Golgi lumen
0.36	GO:0043202	lysosomal lumen
0.35	GO:0031982	vesicle
0.35	GO:0005886	plasma membrane
0.33	GO:0005788	endoplasmic reticulum lumen

0.35

EC:2.7.10.1

GO:0004714

sp|O54689|CCR6_MOUSE
C-C chemokine receptor type 6
Search

CCR6

0.94	CC Chemokine LARC specific receptor

0.80	GO:0070098	chemokine-mediated signaling pathway
0.68	GO:0006935	chemotaxis
0.68	GO:0007186	G-protein coupled receptor signaling pathway
0.67	GO:0006955	immune response
0.65	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.61	GO:1904156	DN3 thymocyte differentiation
0.61	GO:1904155	DN2 thymocyte differentiation
0.60	GO:0072679	thymocyte migration
0.59	GO:0019722	calcium-mediated signaling
0.59	GO:0002523	leukocyte migration involved in inflammatory response

0.81	GO:0004950	chemokine receptor activity
0.67	GO:0019956	chemokine binding
0.38	GO:0051916	granulocyte colony-stimulating factor binding
0.38	GO:0005044	scavenger receptor activity

0.63	GO:0097524	sperm plasma membrane
0.62	GO:0097225	sperm midpiece
0.61	GO:0097228	sperm principal piece
0.56	GO:0009986	cell surface
0.51	GO:0098552	side of membrane
0.46	GO:0044459	plasma membrane part
0.41	GO:0042629	mast cell granule
0.30	GO:0016021	integral component of membrane

sp|O54692|ZW10_MOUSE
Centromere/kinetochore protein zw10 homolog
Search

ZW10

0.91	Centromere/kinetochore protein zw10

0.73	GO:0000278	mitotic cell cycle
0.57	GO:0034501	protein localization to kinetochore
0.57	GO:0051294	establishment of spindle orientation
0.57	GO:0051310	metaphase plate congression
0.56	GO:0007096	regulation of exit from mitosis
0.56	GO:0007030	Golgi organization
0.55	GO:0045930	negative regulation of mitotic cell cycle
0.55	GO:0000075	cell cycle checkpoint
0.55	GO:0006888	ER to Golgi vesicle-mediated transport
0.53	GO:0000819	sister chromatid segregation

0.36	GO:0019237	centromeric DNA binding
0.34	GO:0005515	protein binding

0.75	GO:0000775	chromosome, centromeric region
0.60	GO:0070939	Dsl1/NZR complex
0.60	GO:0005634	nucleus
0.58	GO:0005828	kinetochore microtubule
0.54	GO:0000922	spindle pole
0.49	GO:0005829	cytosol
0.39	GO:0000793	condensed chromosome
0.39	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

sp|O54693|EDA_MOUSE
Ectodysplasin-A
Search

0.89	Ectodysplasin A

0.73	GO:0006955	immune response
0.49	GO:0061152	trachea submucosa development
0.48	GO:0060662	salivary gland cavitation
0.48	GO:0060789	hair follicle placode formation
0.47	GO:0042346	positive regulation of NF-kappaB import into nucleus
0.47	GO:0042476	odontogenesis
0.47	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.46	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.46	GO:0043473	pigmentation
0.45	GO:0007160	cell-matrix adhesion

0.82	GO:0032813	tumor necrosis factor receptor superfamily binding
0.41	GO:0038177	death receptor agonist activity

0.46	GO:0005811	lipid droplet
0.45	GO:0045177	apical part of cell
0.42	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0005887	integral component of plasma membrane
0.35	GO:0005581	collagen trimer
0.33	GO:0005576	extracellular region
0.32	GO:0005856	cytoskeleton

sp|O54707|KLRD1_MOUSE
Natural killer cells antigen CD94
Search

KLRD1

0.96	Killer cell lectin like receptor D1

0.57	GO:0002228	natural killer cell mediated immunity
0.35	GO:0050776	regulation of immune response
0.35	GO:0007166	cell surface receptor signaling pathway

0.70	GO:0030246	carbohydrate binding
0.60	GO:0023024	MHC class I protein complex binding
0.59	GO:0023025	MHC class Ib protein complex binding
0.59	GO:0023029	MHC class Ib protein binding
0.59	GO:1990405	protein antigen binding
0.35	GO:0099600	transmembrane receptor activity
0.34	GO:0038023	signaling receptor activity

0.53	GO:0009897	external side of plasma membrane
0.52	GO:0043235	receptor complex
0.30	GO:0031224	intrinsic component of membrane

sp|O54709|NKG2D_MOUSE
NKG2-D type II integral membrane protein
Search

KLRK1

0.95	Killer cell lectin like receptor K1

0.69	GO:2000502	negative regulation of natural killer cell chemotaxis
0.68	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity
0.65	GO:0042267	natural killer cell mediated cytotoxicity
0.64	GO:0034260	negative regulation of GTPase activity
0.64	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.62	GO:0030101	natural killer cell activation
0.61	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.61	GO:0032729	positive regulation of interferon-gamma production
0.60	GO:0050830	defense response to Gram-positive bacterium
0.59	GO:0071222	cellular response to lipopolysaccharide

0.69	GO:0030246	carbohydrate binding
0.67	GO:0032394	MHC class Ib receptor activity
0.63	GO:0042288	MHC class I protein binding
0.55	GO:0042803	protein homodimerization activity
0.41	GO:0019900	kinase binding

0.59	GO:0009986	cell surface
0.55	GO:0098552	side of membrane
0.48	GO:0044459	plasma membrane part
0.30	GO:0016021	integral component of membrane

sp|O54714|PIAS3_MOUSE
E3 SUMO-protein ligase PIAS3
Search

PIAS3

0.92	Protein inhibitor of activated STAT 3

0.77	GO:0016925	protein sumoylation
0.65	GO:0033235	positive regulation of protein sumoylation
0.65	GO:0033234	negative regulation of protein sumoylation
0.49	GO:0060766	negative regulation of androgen receptor signaling pathway
0.48	GO:0045667	regulation of osteoblast differentiation
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0006351	transcription, DNA-templated

0.78	GO:0019789	SUMO transferase activity
0.63	GO:0008270	zinc ion binding
0.60	GO:0008022	protein C-terminus binding
0.57	GO:0019899	enzyme binding
0.44	GO:0061659	ubiquitin-like protein ligase activity
0.44	GO:0008134	transcription factor binding
0.38	GO:0003677	DNA binding

0.51	GO:0005634	nucleus
0.42	GO:0043233	organelle lumen
0.41	GO:0005737	cytoplasm
0.39	GO:0044446	intracellular organelle part

tr|O54718|O54718_MOUSE
Insulin receptor substrate 3 (Fragment)
Search

0.62	Insulin receptor substrate 3

0.67	GO:0008286	insulin receptor signaling pathway
0.63	GO:0019216	regulation of lipid metabolic process
0.42	GO:0043547	positive regulation of GTPase activity

0.83	GO:0043548	phosphatidylinositol 3-kinase binding
0.72	GO:0005158	insulin receptor binding
0.53	GO:0004871	signal transducer activity
0.42	GO:0005096	GTPase activator activity
0.36	GO:0046872	metal ion binding

0.58	GO:0005829	cytosol
0.55	GO:0005886	plasma membrane
0.43	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

sp|O54724|PTRF_MOUSE
Polymerase I and transcript release factor
Search

CAVIN1

0.97	Polymerase I and transcript release factor a

0.84	GO:0006363	termination of RNA polymerase I transcription
0.59	GO:0006361	transcription initiation from RNA polymerase I promoter
0.59	GO:0009303	rRNA transcription
0.56	GO:2000147	positive regulation of cell motility
0.42	GO:0097320	plasma membrane tubulation
0.41	GO:0030903	notochord development
0.36	GO:2001141	regulation of RNA biosynthetic process
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.34	GO:0007165	signal transduction

0.60	GO:0042134	rRNA primary transcript binding
0.52	GO:0042802	identical protein binding
0.42	GO:0001786	phosphatidylserine binding
0.41	GO:0008307	structural constituent of muscle
0.38	GO:0005080	protein kinase C binding
0.34	GO:0004871	signal transducer activity
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003677	DNA binding

0.82	GO:0005901	caveola
0.48	GO:0005634	nucleus
0.46	GO:0005739	mitochondrion
0.45	GO:0043234	protein complex
0.41	GO:0005829	cytosol
0.39	GO:0015629	actin cytoskeleton
0.39	GO:0043233	organelle lumen
0.37	GO:0005783	endoplasmic reticulum
0.37	GO:0044446	intracellular organelle part

sp|O54732|MMP15_MOUSE
Matrix metalloproteinase-15
Search

MMP15

0.74	Membrane-type matrix metalloproteinase

0.60	GO:0006508	proteolysis
0.59	GO:0035987	endodermal cell differentiation
0.42	GO:0032355	response to estradiol
0.42	GO:0030574	collagen catabolic process
0.40	GO:0035988	chondrocyte proliferation
0.40	GO:0097094	craniofacial suture morphogenesis
0.40	GO:0001958	endochondral ossification
0.39	GO:0048701	embryonic cranial skeleton morphogenesis
0.38	GO:0051604	protein maturation
0.36	GO:0022617	extracellular matrix disassembly

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.40	GO:0070006	metalloaminopeptidase activity
0.35	GO:0008047	enzyme activator activity
0.34	GO:0005515	protein binding
0.33	GO:0004518	nuclease activity

0.73	GO:0031012	extracellular matrix
0.65	GO:0005887	integral component of plasma membrane

0.70

GO:0004222

sp|O54734|OST48_MOUSE
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Search

DDOST

0.78	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

0.85	GO:0018279	protein N-linked glycosylation via asparagine
0.52	GO:0042110	T cell activation
0.50	GO:0034097	response to cytokine
0.38	GO:0006334	nucleosome assembly
0.37	GO:0007018	microtubule-based movement
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0070828	heterochromatin organization
0.32	GO:0006355	regulation of transcription, DNA-templated

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.37	GO:0003777	microtubule motor activity
0.37	GO:0008017	microtubule binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0003677	DNA binding
0.34	GO:0003682	chromatin binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.43	GO:0043234	protein complex
0.41	GO:1990234	transferase complex
0.37	GO:0000786	nucleosome
0.35	GO:0035577	azurophil granule membrane
0.35	GO:0005634	nucleus
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016757

sp|O54743|FOXF2_MOUSE
Forkhead box protein F2
Search

FOXF1

0.96	Forkhead box protein F2

0.63	GO:0048566	embryonic digestive tract development
0.61	GO:0001738	morphogenesis of a polarized epithelium
0.60	GO:0048562	embryonic organ morphogenesis
0.59	GO:0048806	genitalia development
0.59	GO:0030198	extracellular matrix organization
0.59	GO:0060021	palate development
0.58	GO:0006366	transcription by RNA polymerase II
0.58	GO:0045944	positive regulation of transcription by RNA polymerase II
0.57	GO:0031076	embryonic camera-type eye development
0.56	GO:0007164	establishment of tissue polarity

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.59	GO:0001012	RNA polymerase II regulatory region DNA binding
0.56	GO:0003690	double-stranded DNA binding
0.53	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.52	GO:0008134	transcription factor binding

0.60	GO:0005634	nucleus
0.54	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|O54749|CP2J5_MOUSE
Cytochrome P450 2J5
Search

CYP2J2

0.94	Cytochrome P450 family 2 subfamily J member 2

0.53	GO:0043651	linoleic acid metabolic process
0.53	GO:0019373	epoxygenase P450 pathway
0.53	GO:0055114	oxidation-reduction process
0.41	GO:1903532	positive regulation of secretion by cell
0.41	GO:0032966	negative regulation of collagen biosynthetic process
0.41	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway
0.40	GO:1904467	regulation of tumor necrosis factor secretion
0.40	GO:0051240	positive regulation of multicellular organismal process
0.40	GO:2000861	regulation of estrogen secretion
0.39	GO:0007565	female pregnancy

0.79	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.55	GO:0008404	arachidonic acid 14,15-epoxygenase activity
0.55	GO:0008405	arachidonic acid 11,12-epoxygenase activity
0.55	GO:0071614	linoleic acid epoxygenase activity
0.39	GO:0003958	NADPH-hemoprotein reductase activity

0.41	GO:0005783	endoplasmic reticulum
0.39	GO:0070062	extracellular exosome
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.36	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:1.14.14

GO:0016712

sp|O54750|CP2J6_MOUSE
Cytochrome P450 2J6
Search

CYP2J2

0.94	Cytochrome P450 family 2 subfamily J member 2

0.54	GO:0043651	linoleic acid metabolic process
0.53	GO:0019373	epoxygenase P450 pathway
0.53	GO:0055114	oxidation-reduction process
0.42	GO:0032966	negative regulation of collagen biosynthetic process
0.42	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway
0.41	GO:1904469	positive regulation of tumor necrosis factor secretion
0.40	GO:0007565	female pregnancy
0.40	GO:0001523	retinoid metabolic process
0.39	GO:0014070	response to organic cyclic compound
0.38	GO:2000863	positive regulation of estrogen secretion

0.78	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.56	GO:0008404	arachidonic acid 14,15-epoxygenase activity
0.56	GO:0008405	arachidonic acid 11,12-epoxygenase activity
0.55	GO:0071614	linoleic acid epoxygenase activity
0.40	GO:0003958	NADPH-hemoprotein reductase activity
0.36	GO:0008395	steroid hydroxylase activity

0.41	GO:0005783	endoplasmic reticulum
0.39	GO:0070062	extracellular exosome
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.36	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:1.14.14

GO:0016712

sp|O54751|CRX_MOUSE
Cone-rod homeobox protein
Search

CRX

0.97	Cone-rod homeobox containing gene

0.76	GO:0007623	circadian rhythm
0.73	GO:0007601	visual perception
0.69	GO:0007275	multicellular organism development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0006366	transcription by RNA polymerase II
0.51	GO:0051254	positive regulation of RNA metabolic process
0.51	GO:0010557	positive regulation of macromolecule biosynthetic process
0.51	GO:0031328	positive regulation of cellular biosynthetic process

0.62	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0043522	leucine zipper domain binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding
0.41	GO:0035257	nuclear hormone receptor binding
0.37	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.36	GO:0005667	transcription factor complex

sp|O54754|AOXA_MOUSE
Aldehyde oxidase 1
Search

AOX1

0.53	aldehyde oxidase

0.60	GO:0022900	electron transport chain
0.52	GO:0009115	xanthine catabolic process
0.44	GO:0017144	drug metabolic process
0.34	GO:0006805	xenobiotic metabolic process
0.33	GO:0072524	pyridine-containing compound metabolic process
0.33	GO:0006766	vitamin metabolic process

0.70	GO:0051537	2 iron, 2 sulfur cluster binding
0.67	GO:0051287	NAD binding
0.66	GO:0050660	flavin adenine dinucleotide binding
0.65	GO:0043546	molybdopterin cofactor binding
0.65	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.62	GO:0005506	iron ion binding
0.61	GO:0009055	electron transfer activity
0.61	GO:0004031	aldehyde oxidase activity
0.51	GO:0042803	protein homodimerization activity
0.49	GO:0004854	xanthine dehydrogenase activity

0.50	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome

0.65

EC:1.1

GO:0016614

sp|O54774|AP3D1_MOUSE
AP-3 complex subunit delta-1
Search

AP3D1

0.73	AP-3 complex subunit delta

0.68	GO:0006886	intracellular protein transport
0.67	GO:0016192	vesicle-mediated transport
0.58	GO:0048499	synaptic vesicle membrane organization
0.58	GO:0048007	antigen processing and presentation, exogenous lipid antigen via MHC class Ib
0.57	GO:0051138	positive regulation of NK T cell differentiation
0.57	GO:0035646	endosome to melanosome transport
0.56	GO:0061088	regulation of sequestering of zinc ion
0.56	GO:0061462	protein localization to lysosome
0.55	GO:0008089	anterograde axonal transport
0.54	GO:0047496	vesicle transport along microtubule

0.34

GO:0005515

protein binding

0.80	GO:0030123	AP-3 adaptor complex
0.59	GO:0098830	presynaptic endosome
0.55	GO:1904115	axon cytoplasm
0.55	GO:0043195	terminal bouton
0.52	GO:0010008	endosome membrane
0.50	GO:0005794	Golgi apparatus
0.41	GO:0005886	plasma membrane
0.35	GO:0031984	organelle subcompartment
0.35	GO:0005765	lysosomal membrane
0.30	GO:0016021	integral component of membrane

sp|O54775|WISP1_MOUSE
WNT1-inducible-signaling pathway protein 1
Search

WISP1

0.97	WNT1-inducible-signaling pathway protein 1

0.77	GO:0001558	regulation of cell growth
0.46	GO:0060548	negative regulation of cell death
0.44	GO:0007267	cell-cell signaling
0.44	GO:0007155	cell adhesion
0.40	GO:0007165	signal transduction
0.37	GO:0030510	regulation of BMP signaling pathway
0.37	GO:0051216	cartilage development
0.37	GO:0008284	positive regulation of cell proliferation
0.37	GO:0045597	positive regulation of cell differentiation
0.37	GO:0002041	intussusceptive angiogenesis

0.82	GO:0005520	insulin-like growth factor binding
0.48	GO:0005178	integrin binding
0.47	GO:0008201	heparin binding
0.36	GO:0050840	extracellular matrix binding

0.66	GO:0005576	extracellular region
0.47	GO:0005829	cytosol
0.33	GO:0005783	endoplasmic reticulum

sp|O54781|SRPK2_MOUSE
SRSF protein kinase 2
Search

SRPK2

0.95	SRSF protein kinase 2

0.62	GO:0006468	protein phosphorylation
0.58	GO:0045070	positive regulation of viral genome replication
0.58	GO:0045071	negative regulation of viral genome replication
0.56	GO:0000245	spliceosomal complex assembly
0.54	GO:0008284	positive regulation of cell proliferation
0.47	GO:0035556	intracellular signal transduction
0.45	GO:0050684	regulation of mRNA processing
0.42	GO:0035063	nuclear speck organization
0.41	GO:0043525	positive regulation of neuron apoptotic process
0.40	GO:0001525	angiogenesis

0.62	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0000287	magnesium ion binding
0.41	GO:0071889	14-3-3 protein binding
0.35	GO:0003723	RNA binding

0.51	GO:0005730	nucleolus
0.49	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol

sp|O54782|MA2B2_MOUSE
Epididymis-specific alpha-mannosidase
Search

MAN2B2

0.47	Epididymis-specific alpha-mannosidase

0.81	GO:0006013	mannose metabolic process
0.50	GO:0006517	protein deglycosylation
0.35	GO:0009313	oligosaccharide catabolic process

0.79	GO:0004559	alpha-mannosidase activity
0.69	GO:0030246	carbohydrate binding
0.52	GO:0046872	metal ion binding

0.43	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.39	GO:0005764	lysosome
0.36	GO:0005775	vacuolar lumen
0.30	GO:0016021	integral component of membrane

0.79

EC:3.2.1.24

GO:0004559

sp|O54784|DAPK3_MOUSE
Death-associated protein kinase 3
Search

DAPK3

0.96	Death-associated protein kinase 3

0.62	GO:0006468	protein phosphorylation
0.59	GO:0006915	apoptotic process
0.57	GO:0043519	regulation of myosin II filament organization
0.55	GO:0071346	cellular response to interferon-gamma
0.54	GO:2000249	regulation of actin cytoskeleton reorganization
0.54	GO:0090109	regulation of cell-substrate junction assembly
0.54	GO:1903391	regulation of adherens junction organization
0.53	GO:0001952	regulation of cell-matrix adhesion
0.53	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.53	GO:0030335	positive regulation of cell migration

0.66	GO:0004674	protein serine/threonine kinase activity
0.56	GO:0043522	leucine zipper domain binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.50	GO:0017048	Rho GTPase binding
0.50	GO:0042802	identical protein binding
0.46	GO:0046983	protein dimerization activity
0.40	GO:0008022	protein C-terminus binding

0.54	GO:0016605	PML body
0.40	GO:0005884	actin filament
0.40	GO:0098857	membrane microdomain
0.38	GO:0005737	cytoplasm
0.37	GO:0000775	chromosome, centromeric region
0.35	GO:0012505	endomembrane system
0.35	GO:0005815	microtubule organizing center
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.66

GO:0004674

sp|O54785|LIMK2_MOUSE
LIM domain kinase 2
Search

LIMK2

0.97	LIM domain kinase 2

0.63	GO:0006468	protein phosphorylation
0.51	GO:0007283	spermatogenesis
0.40	GO:0035556	intracellular signal transduction
0.36	GO:0042325	regulation of phosphorylation
0.34	GO:0007281	germ cell development

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.48	GO:0046982	protein heterodimerization activity
0.40	GO:0004871	signal transducer activity

0.52	GO:0005801	cis-Golgi network
0.44	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm

sp|O54786|DFFA_MOUSE
DNA fragmentation factor subunit alpha
Search

DFFA

0.95	DNA fragmentation factor subunit alpha

0.85	GO:1902511	negative regulation of apoptotic DNA fragmentation
0.84	GO:0070242	thymocyte apoptotic process
0.81	GO:0032076	negative regulation of deoxyribonuclease activity
0.72	GO:0043065	positive regulation of apoptotic process
0.71	GO:0061077	chaperone-mediated protein folding
0.40	GO:0006309	apoptotic DNA fragmentation
0.34	GO:0007165	signal transduction

0.82	GO:0060703	deoxyribonuclease inhibitor activity
0.78	GO:0044183	protein binding involved in protein folding
0.70	GO:0019904	protein domain specific binding
0.31	GO:0016787	hydrolase activity

0.69	GO:0000790	nuclear chromatin
0.63	GO:0005829	cytosol
0.60	GO:0005811	lipid droplet
0.52	GO:0005886	plasma membrane
0.37	GO:0005654	nucleoplasm

0.31

GO:0016787

sp|O54788|DFFB_MOUSE
DNA fragmentation factor subunit beta
Search

DFFB

0.97	DNAation factor subunit beta

0.85	GO:0006309	apoptotic DNA fragmentation
0.42	GO:0030263	apoptotic chromosome condensation
0.39	GO:0051260	protein homooligomerization
0.36	GO:0007420	brain development

0.51	GO:0016787	hydrolase activity
0.42	GO:0003677	DNA binding
0.42	GO:0140097	catalytic activity, acting on DNA
0.41	GO:0097718	disordered domain specific binding
0.38	GO:0042802	identical protein binding
0.38	GO:0019899	enzyme binding

0.61	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.49	GO:0005737	cytoplasm
0.45	GO:0000785	chromatin

0.51

GO:0016787

sp|O54790|MAFG_MOUSE
Transcription factor MafG
Search

MAFG

0.94	Transcription factor MafG

0.57	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0045604	regulation of epidermal cell differentiation
0.48	GO:0030534	adult behavior
0.47	GO:0001701	in utero embryonic development
0.46	GO:0042127	regulation of cell proliferation
0.45	GO:0051254	positive regulation of RNA metabolic process
0.45	GO:0010557	positive regulation of macromolecule biosynthetic process

0.74	GO:0046982	protein heterodimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.46	GO:0001067	regulatory region nucleic acid binding

0.61	GO:0005634	nucleus
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part

sp|O54791|MAFF_MOUSE
Transcription factor MafF
Search

MAFF

0.93	Transcription factor MafF

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0006351	transcription, DNA-templated
0.45	GO:0045604	regulation of epidermal cell differentiation
0.45	GO:0035914	skeletal muscle cell differentiation
0.44	GO:0001701	in utero embryonic development
0.41	GO:1902680	positive regulation of RNA biosynthetic process
0.41	GO:0007567	parturition
0.39	GO:0007596	blood coagulation

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.36	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.39	GO:0005739	mitochondrion
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part

sp|O54792|HES2_MOUSE
Transcription factor HES-2
Search

HES2

0.87	Transcription factor HES-2

0.56	GO:0006351	transcription, DNA-templated
0.55	GO:0006355	regulation of transcription, DNA-templated
0.49	GO:0061106	negative regulation of stomach neuroendocrine cell differentiation
0.49	GO:2000974	negative regulation of pro-B cell differentiation
0.49	GO:0007262	STAT protein import into nucleus
0.49	GO:2000227	negative regulation of pancreatic A cell differentiation
0.49	GO:0072141	renal interstitial fibroblast development
0.49	GO:0035910	ascending aorta morphogenesis
0.49	GO:0007219	Notch signaling pathway
0.49	GO:0045977	positive regulation of mitotic cell cycle, embryonic

0.68	GO:0046983	protein dimerization activity
0.53	GO:0003677	DNA binding
0.49	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0042826	histone deacetylase binding
0.46	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0051087	chaperone binding
0.44	GO:0042802	identical protein binding
0.41	GO:0008134	transcription factor binding
0.35	GO:0008432	JUN kinase binding
0.34	GO:0003682	chromatin binding

0.59	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome
0.30	GO:0016020	membrane

sp|O54794|AQP7_MOUSE
Aquaporin-7
Search

AQP7

0.81	Aquaporin-7

0.60	GO:0015793	glycerol transport
0.59	GO:0006833	water transport
0.55	GO:0055085	transmembrane transport
0.54	GO:0003091	renal water homeostasis
0.54	GO:0070293	renal absorption
0.46	GO:0015840	urea transport
0.39	GO:0006863	purine nucleobase transport
0.38	GO:0071320	cellular response to cAMP
0.38	GO:0015837	amine transport
0.37	GO:0046689	response to mercury ion

0.69	GO:0022803	passive transmembrane transporter activity
0.49	GO:0015168	glycerol transmembrane transporter activity
0.49	GO:0005372	water transmembrane transporter activity
0.46	GO:0015204	urea transmembrane transporter activity
0.39	GO:0005345	purine nucleobase transmembrane transporter activity
0.37	GO:0005350	pyrimidine nucleobase transmembrane transporter activity
0.37	GO:0015105	arsenite transmembrane transporter activity

0.37	GO:0005911	cell-cell junction
0.35	GO:0044459	plasma membrane part
0.35	GO:0005903	brush border
0.35	GO:0046930	pore complex
0.34	GO:0043227	membrane-bounded organelle
0.34	GO:0043230	extracellular organelle
0.34	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0005615	extracellular space
0.34	GO:0043229	intracellular organelle
0.33	GO:0005737	cytoplasm

sp|O54798|BRS3_MOUSE
Bombesin receptor subtype-3
Search

BRS3

0.94	Gastrin releasing peptide receptor

0.79	GO:0031989	bombesin receptor signaling pathway
0.52	GO:0036343	psychomotor behavior
0.50	GO:0035176	social behavior
0.49	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.48	GO:0007218	neuropeptide signaling pathway
0.46	GO:0042127	regulation of cell proliferation
0.44	GO:0043207	response to external biotic stimulus
0.35	GO:0008343	adult feeding behavior
0.35	GO:0008217	regulation of blood pressure
0.34	GO:0006006	glucose metabolic process

0.79	GO:0004946	bombesin receptor activity
0.34	GO:0042923	neuropeptide binding
0.32	GO:0003723	RNA binding

0.44	GO:0005887	integral component of plasma membrane
0.41	GO:0005829	cytosol
0.38	GO:0043025	neuronal cell body
0.38	GO:0043005	neuron projection

sp|O54799|NMBR_MOUSE
Neuromedin-B receptor
Search

NMBR

0.97	Neuromedin B receptor

0.80	GO:0031989	bombesin receptor signaling pathway
0.46	GO:0036343	psychomotor behavior
0.44	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.44	GO:0035176	social behavior
0.43	GO:0007218	neuropeptide signaling pathway
0.42	GO:0042127	regulation of cell proliferation
0.40	GO:0043207	response to external biotic stimulus

0.80

GO:0004946

bombesin receptor activity

0.49	GO:0005829	cytosol
0.44	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|O54803|P2RX6_MOUSE
P2X purinoceptor 6
Search

P2RX6

0.86	Purinergic receptor P2X 6

0.85	GO:0033198	response to ATP
0.85	GO:0035590	purinergic nucleotide receptor signaling pathway
0.80	GO:0060079	excitatory postsynaptic potential
0.65	GO:0051260	protein homooligomerization
0.61	GO:0098655	cation transmembrane transport

0.85	GO:0004931	extracellularly ATP-gated cation channel activity
0.85	GO:0016502	nucleotide receptor activity
0.84	GO:0035586	purinergic receptor activity
0.62	GO:0042802	identical protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.78	GO:0098794	postsynapse
0.67	GO:0005887	integral component of plasma membrane
0.62	GO:0030054	cell junction
0.45	GO:0005737	cytoplasm

sp|O54804|CHKA_MOUSE
Choline kinase alpha
Search

CHKA

0.96	Choline kinase alpha

0.57	GO:0006657	CDP-choline pathway
0.55	GO:0016310	phosphorylation
0.53	GO:0006646	phosphatidylethanolamine biosynthetic process
0.43	GO:1904681	response to 3-methylcholanthrene
0.40	GO:0006580	ethanolamine metabolic process
0.39	GO:0019695	choline metabolic process
0.37	GO:0009636	response to toxic substance
0.35	GO:0006869	lipid transport
0.33	GO:0007165	signal transduction

0.59	GO:0004305	ethanolamine kinase activity
0.59	GO:0004103	choline kinase activity
0.55	GO:0004104	cholinesterase activity
0.51	GO:0042803	protein homodimerization activity
0.41	GO:0008144	drug binding
0.40	GO:0033265	choline binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004871	signal transducer activity

0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.59	EC:2.7.1.82	GO:0004305
0.59	KEGG:R01468	GO:0004305

sp|O54818|TPD53_MOUSE
Tumor protein D53
Search

TPD52L1

0.97	Tumor protein D52 like 1

0.82	GO:0000086	G2/M transition of mitotic cell cycle
0.76	GO:0046330	positive regulation of JNK cascade
0.75	GO:2001235	positive regulation of apoptotic signaling pathway
0.73	GO:0043406	positive regulation of MAP kinase activity

0.72	GO:0042803	protein homodimerization activity
0.67	GO:0046982	protein heterodimerization activity

0.76	GO:0048471	perinuclear region of cytoplasm
0.60	GO:0005769	early endosome
0.30	GO:0016020	membrane

sp|O54819|TFPI1_MOUSE
Tissue factor pathway inhibitor
Search

TFPI

0.79	Tissue factor pathway inhibitor

0.78	GO:0007596	blood coagulation
0.76	GO:0010951	negative regulation of endopeptidase activity
0.69	GO:0030195	negative regulation of blood coagulation
0.63	GO:0071383	cellular response to steroid hormone stimulus
0.43	GO:0032355	response to estradiol
0.42	GO:0071347	cellular response to interleukin-1
0.42	GO:0071222	cellular response to lipopolysaccharide
0.38	GO:0072376	protein activation cascade

0.79

GO:0004867

serine-type endopeptidase inhibitor activity

0.67	GO:0005901	caveola
0.66	GO:0005576	extracellular region
0.61	GO:0009986	cell surface
0.37	GO:0031225	anchored component of membrane
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

sp|O54824|IL16_MOUSE
Pro-interleukin-16
Search

IL16

0.90	Pro-interleukin-16

0.72	GO:0010469	regulation of receptor activity
0.68	GO:0006935	chemotaxis
0.63	GO:0050930	induction of positive chemotaxis
0.59	GO:0050900	leukocyte migration
0.59	GO:0051924	regulation of calcium ion transport
0.51	GO:0070887	cellular response to chemical stimulus
0.38	GO:0006351	transcription, DNA-templated
0.37	GO:2001141	regulation of RNA biosynthetic process
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression

0.77	GO:0005125	cytokine activity
0.57	GO:0042609	CD4 receptor binding

0.70	GO:0005615	extracellular space
0.59	GO:0005634	nucleus
0.51	GO:0005829	cytosol
0.51	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.44	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|O54825|BYST_MOUSE
Bystin
Search

BYSL

0.85	Bystin like

0.85	GO:0001829	trophectodermal cell differentiation
0.81	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.79	GO:0008283	cell proliferation
0.41	GO:0007155	cell adhesion
0.40	GO:0071347	cellular response to interleukin-1
0.40	GO:0007565	female pregnancy
0.40	GO:0071222	cellular response to lipopolysaccharide
0.39	GO:0071363	cellular response to growth factor stimulus
0.39	GO:0007420	brain development
0.39	GO:0071407	cellular response to organic cyclic compound

0.38	GO:0003723	RNA binding
0.36	GO:0005515	protein binding

0.80	GO:0045177	apical part of cell
0.73	GO:0005730	nucleolus
0.49	GO:0005737	cytoplasm
0.38	GO:0005874	microtubule
0.37	GO:0005654	nucleoplasm
0.37	GO:0042995	cell projection
0.30	GO:0031224	intrinsic component of membrane

sp|O54826|AF10_MOUSE
Protein AF-10
Search

MLLT10

0.97	MLLT10, histone lysine methyltransferase DOT1L cofactor

0.64	GO:0045944	positive regulation of transcription by RNA polymerase II
0.43	GO:0060729	intestinal epithelial structure maintenance
0.41	GO:0060070	canonical Wnt signaling pathway

0.54

GO:0046872

metal ion binding

0.60	GO:0005654	nucleoplasm
0.59	GO:0005829	cytosol
0.52	GO:0043234	protein complex

sp|O54827|AT10A_MOUSE
Probable phospholipid-transporting ATPase VA
Search

ATP10A

0.58	Phospholipid-transporting ATPase

0.80	GO:0045332	phospholipid translocation
0.34	GO:0008360	regulation of cell shape
0.34	GO:0034220	ion transmembrane transport
0.33	GO:0006812	cation transport

0.80	GO:0004012	phospholipid-translocating ATPase activity
0.64	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.53	GO:0005783	endoplasmic reticulum
0.42	GO:0005654	nucleoplasm
0.42	GO:0005886	plasma membrane
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:3.6.3.1

GO:0004012

sp|O54828|RGS9_MOUSE
Regulator of G-protein signaling 9
Search

RGS9

0.94	Regulator of G-protein signaling 9

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.62	GO:0035556	intracellular signal transduction
0.46	GO:0043547	positive regulation of GTPase activity
0.40	GO:0007601	visual perception
0.40	GO:0043627	response to estrogen
0.40	GO:0009968	negative regulation of signal transduction
0.39	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.38	GO:0007399	nervous system development
0.34	GO:0006457	protein folding

0.63	GO:0004871	signal transducer activity
0.46	GO:0005096	GTPase activator activity
0.38	GO:0032403	protein complex binding
0.38	GO:0031681	G-protein beta-subunit binding

0.80	GO:1905360	GTPase complex
0.79	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.65	GO:0098797	plasma membrane protein complex
0.58	GO:0001917	photoreceptor inner segment
0.57	GO:0001750	photoreceptor outer segment
0.37	GO:0060170	ciliary membrane
0.37	GO:0005737	cytoplasm
0.36	GO:0005634	nucleus
0.34	GO:0044292	dendrite terminus
0.30	GO:0031224	intrinsic component of membrane

sp|O54829|RGS7_MOUSE
Regulator of G-protein signaling 7
Search

RGS7

0.93	Regulator of G-protein signalling 7

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.59	GO:0035556	intracellular signal transduction
0.50	GO:0043547	positive regulation of GTPase activity
0.37	GO:0009968	negative regulation of signal transduction
0.37	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.33	GO:0006457	protein folding

0.63	GO:0004871	signal transducer activity
0.55	GO:0031681	G-protein beta-subunit binding
0.50	GO:0005096	GTPase activator activity

0.80	GO:0005834	heterotrimeric G-protein complex
0.46	GO:0005829	cytosol
0.37	GO:0044292	dendrite terminus
0.34	GO:0005634	nucleus

sp|O54830|PR7A1_MOUSE
Prolactin-7A1
Search

0.76	GO:0010469	regulation of receptor activity
0.47	GO:0045723	positive regulation of fatty acid biosynthetic process
0.46	GO:0030072	peptide hormone secretion
0.44	GO:0043066	negative regulation of apoptotic process
0.43	GO:1903489	positive regulation of lactation
0.42	GO:0010751	negative regulation of nitric oxide mediated signal transduction
0.42	GO:0010628	positive regulation of gene expression
0.42	GO:0032501	multicellular organismal process
0.41	GO:0007589	body fluid secretion
0.39	GO:0033685	negative regulation of luteinizing hormone secretion

0.79	GO:0005179	hormone activity
0.49	GO:0005148	prolactin receptor binding

0.66	GO:0005576	extracellular region
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005829	cytosol

sp|O54831|PR7A2_MOUSE
Prolactin-7A2
Search

0.97	Prolactin family 7, subfamily a, member 3

0.76	GO:0010469	regulation of receptor activity
0.44	GO:0007565	female pregnancy

0.79

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

tr|O54832|O54832_MOUSE
Decidual PRL-related protein
Search

0.97	Prolactin-like protein-C variant

0.76	GO:0010469	regulation of receptor activity
0.56	GO:0007565	female pregnancy
0.48	GO:0001666	response to hypoxia
0.46	GO:0048609	multicellular organismal reproductive process
0.42	GO:0045723	positive regulation of fatty acid biosynthetic process
0.41	GO:0030072	peptide hormone secretion
0.40	GO:0043066	negative regulation of apoptotic process
0.39	GO:1903489	positive regulation of lactation
0.39	GO:0010751	negative regulation of nitric oxide mediated signal transduction
0.39	GO:0010628	positive regulation of gene expression

0.79	GO:0005179	hormone activity
0.43	GO:0005148	prolactin receptor binding

0.66	GO:0005576	extracellular region
0.34	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|O54833|CSK22_MOUSE
Casein kinase II subunit alpha'
Search

CSNK2A2

0.79	Casein kinase II subunit alpha'

0.63	GO:0006468	protein phosphorylation
0.56	GO:1903146	regulation of autophagy of mitochondrion
0.55	GO:1903955	positive regulation of protein targeting to mitochondrion
0.53	GO:1905818	regulation of chromosome separation
0.40	GO:0097421	liver regeneration
0.39	GO:0021987	cerebral cortex development
0.38	GO:0007283	spermatogenesis
0.38	GO:0016055	Wnt signaling pathway
0.37	GO:0006915	apoptotic process
0.35	GO:0007049	cell cycle

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0047485	protein N-terminus binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0031519	PcG protein complex
0.39	GO:0001669	acrosomal vesicle
0.37	GO:0000785	chromatin
0.35	GO:0005956	protein kinase CK2 complex
0.34	GO:0005886	plasma membrane
0.34	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol

0.68

GO:0004674

sp|O54834|RHG06_MOUSE
Rho GTPase-activating protein 6
Search

ARHGAP6

0.93	Rho GTPase-activating protein 6

0.74	GO:0043547	positive regulation of GTPase activity
0.73	GO:0007015	actin filament organization
0.59	GO:0007165	signal transduction
0.59	GO:0051497	negative regulation of stress fiber assembly
0.59	GO:0051895	negative regulation of focal adhesion assembly
0.58	GO:0048041	focal adhesion assembly
0.42	GO:0007202	activation of phospholipase C activity
0.35	GO:0051258	protein polymerization
0.35	GO:0051056	regulation of small GTPase mediated signal transduction
0.35	GO:0009967	positive regulation of signal transduction

0.75	GO:0005096	GTPase activator activity
0.42	GO:0016004	phospholipase activator activity
0.42	GO:0043274	phospholipase binding
0.38	GO:0017124	SH3 domain binding
0.36	GO:0005070	SH3/SH2 adaptor activity

0.50	GO:0015629	actin cytoskeleton
0.39	GO:0005737	cytoplasm
0.35	GO:0099513	polymeric cytoskeletal fiber

sp|O54836|ZMAT3_MOUSE
Zinc finger matrin-type protein 3
Search

0.57	Zinc finger matrin-type protein 3

0.30	GO:0012501	programmed cell death
0.30	GO:0051234	establishment of localization
0.30	GO:0051128	regulation of cellular component organization
0.30	GO:0006974	cellular response to DNA damage stimulus
0.30	GO:0008104	protein localization
0.30	GO:0023052	signaling
0.30	GO:0040008	regulation of growth
0.30	GO:0048523	negative regulation of cellular process
0.30	GO:0007154	cell communication

0.62	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.30	GO:0002039	p53 binding

0.36	GO:0005654	nucleoplasm
0.34	GO:0005886	plasma membrane
0.30	GO:0005730	nucleolus
0.30	GO:0044425	membrane part

sp|O54839|EOMES_MOUSE
Eomesodermin homolog
Search

EOMES

0.95	T-box transcription factor Eomesodermin

0.65	GO:0002302	CD8-positive, alpha-beta T cell differentiation involved in immune response
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0007420	brain development
0.56	GO:0010468	regulation of gene expression
0.54	GO:0051254	positive regulation of RNA metabolic process
0.53	GO:0010557	positive regulation of macromolecule biosynthetic process
0.53	GO:0031328	positive regulation of cellular biosynthetic process
0.53	GO:0001714	endodermal cell fate specification

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.48	GO:0001102	RNA polymerase II activating transcription factor binding
0.48	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.46	GO:0001067	regulatory region nucleic acid binding
0.45	GO:0003682	chromatin binding
0.35	GO:0005452	inorganic anion exchanger activity
0.33	GO:0019901	protein kinase binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding

0.61	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|O54851|CXD2_MOUSE
Gap junction delta-2 protein
Search

GJD2

0.64	Gap junction delta-2 protein (Fragment)

0.60	GO:0007154	cell communication
0.56	GO:0001508	action potential
0.53	GO:0007601	visual perception
0.45	GO:0023052	signaling
0.39	GO:0007416	synapse assembly
0.34	GO:0055085	transmembrane transport
0.34	GO:0006811	ion transport

0.38	GO:0005243	gap junction channel activity
0.35	GO:0022832	voltage-gated channel activity
0.35	GO:0022839	ion gated channel activity
0.35	GO:0008381	mechanosensitive ion channel activity
0.33	GO:0005515	protein binding

0.84	GO:0005922	connexin complex
0.30	GO:0031224	intrinsic component of membrane

sp|O54863|TSSK2_MOUSE
Testis-specific serine/threonine-protein kinase 2
Search

TSSK2

0.96	LOW QUALITY PROTEIN: testis-specific serine/threonine-protein kinase 1

0.63	GO:0006468	protein phosphorylation
0.57	GO:0007286	spermatid development
0.44	GO:0035556	intracellular signal transduction
0.37	GO:0007275	multicellular organism development
0.34	GO:0043066	negative regulation of apoptotic process
0.32	GO:0032870	cellular response to hormone stimulus
0.32	GO:0006508	proteolysis

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0000287	magnesium ion binding
0.36	GO:0005515	protein binding
0.32	GO:0070001	aspartic-type peptidase activity
0.32	GO:0004175	endopeptidase activity

0.53	GO:0001669	acrosomal vesicle
0.51	GO:0005814	centriole
0.45	GO:0031514	motile cilium
0.43	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004674

sp|O54864|SUV91_MOUSE
Histone-lysine N-methyltransferase SUV39H1
Search

SUV39H1

0.52	Histone-lysine N-methyltransferase

0.79	GO:0034968	histone lysine methylation
0.63	GO:0061647	histone H3-K9 modification
0.58	GO:0071456	cellular response to hypoxia
0.55	GO:0000183	chromatin silencing at rDNA
0.54	GO:0000122	negative regulation of transcription by RNA polymerase II
0.45	GO:0006974	cellular response to DNA damage stimulus
0.43	GO:0031017	exocrine pancreas development
0.42	GO:0006333	chromatin assembly or disassembly
0.42	GO:0060042	retina morphogenesis in camera-type eye
0.42	GO:0006338	chromatin remodeling

0.79	GO:0018024	histone-lysine N-methyltransferase activity
0.62	GO:0008270	zinc ion binding
0.54	GO:0047485	protein N-terminus binding
0.42	GO:1904047	S-adenosyl-L-methionine binding
0.38	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.35	GO:0001012	RNA polymerase II regulatory region DNA binding
0.34	GO:0003682	chromatin binding

0.65	GO:0005694	chromosome
0.61	GO:0005634	nucleus
0.53	GO:0017053	transcriptional repressor complex
0.47	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part

0.79

GO:0018024

sp|O54865|GCYB1_MOUSE
Guanylate cyclase soluble subunit beta-1
Search

GUCY1B3

0.95	Guanylate cyclase soluble subunit beta-1

0.81	GO:0006182	cGMP biosynthetic process
0.61	GO:0035556	intracellular signal transduction
0.56	GO:0099555	trans-synaptic signaling by nitric oxide, modulating synaptic transmission
0.41	GO:0071732	cellular response to nitric oxide
0.36	GO:0006171	cAMP biosynthetic process
0.35	GO:0008015	blood circulation

0.81	GO:0004383	guanylate cyclase activity
0.62	GO:0020037	heme binding
0.51	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.46	GO:0004016	adenylate cyclase activity
0.40	GO:0047805	cytidylate cyclase activity
0.38	GO:0051879	Hsp90 protein binding
0.37	GO:0046982	protein heterodimerization activity
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0046872	metal ion binding

0.49	GO:0008074	guanylate cyclase complex, soluble
0.38	GO:0005886	plasma membrane
0.38	GO:0048786	presynaptic active zone

0.81	EC:4.6.1.2	GO:0004383
0.40	KEGG:R00574	GO:0047805

sp|O54879|HMGB3_MOUSE
High mobility group protein B3
Search

HMGB3

0.96	High mobility group box 3

0.56	GO:0032392	DNA geometric change
0.52	GO:0045578	negative regulation of B cell differentiation
0.49	GO:0045638	negative regulation of myeloid cell differentiation
0.38	GO:0045087	innate immune response
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.34	GO:0006310	DNA recombination
0.33	GO:0007275	multicellular organism development

0.67	GO:0000400	four-way junction DNA binding
0.67	GO:0008301	DNA binding, bending
0.40	GO:0003723	RNA binding
0.35	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.36	GO:0005694	chromosome
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|O54885|TYOBP_MOUSE
TYRO protein tyrosine kinase-binding protein
Search

TYROBP

0.97	TYRO protein tyrosine kinase-binding protein isoform 1

0.75	GO:0002281	macrophage activation involved in immune response
0.75	GO:2001204	regulation of osteoclast development
0.73	GO:0002283	neutrophil activation involved in immune response
0.67	GO:0007229	integrin-mediated signaling pathway
0.49	GO:0016310	phosphorylation
0.47	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.44	GO:0050776	regulation of immune response
0.38	GO:0006968	cellular defense response
0.38	GO:0002446	neutrophil mediated immunity
0.38	GO:0043299	leukocyte degranulation

0.62	GO:0005102	receptor binding
0.62	GO:0042802	identical protein binding
0.50	GO:0016301	kinase activity
0.48	GO:0043548	phosphatidylinositol 3-kinase binding
0.40	GO:0005057	signal transducer activity, downstream of receptor

0.64	GO:0009986	cell surface
0.38	GO:0030667	secretory granule membrane
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|O54887|TSKS_MOUSE
Testis-specific serine kinase substrate
Search

TSKS

0.97	Testis-specific serine kinase substrate

0.73	GO:0010923	negative regulation of phosphatase activity
0.46	GO:0016310	phosphorylation

0.70	GO:0019901	protein kinase binding
0.48	GO:0016301	kinase activity

0.74	GO:0005814	centriole
0.60	GO:0001669	acrosomal vesicle

sp|O54890|ITB3_MOUSE
Integrin beta-3
Search

ITGB3

0.68	Integrin beta

0.86	GO:0060055	angiogenesis involved in wound healing
0.85	GO:0070527	platelet aggregation
0.85	GO:0007044	cell-substrate junction assembly
0.82	GO:0007160	cell-matrix adhesion
0.80	GO:0007229	integrin-mediated signaling pathway
0.79	GO:0030334	regulation of cell migration
0.55	GO:0033690	positive regulation of osteoblast proliferation
0.54	GO:0036120	cellular response to platelet-derived growth factor stimulus
0.54	GO:0043277	apoptotic cell clearance
0.54	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading

0.65	GO:0004872	receptor activity
0.54	GO:0005178	integrin binding
0.53	GO:0005080	protein kinase C binding
0.40	GO:0042802	identical protein binding
0.38	GO:0038132	neuregulin binding
0.38	GO:0043184	vascular endothelial growth factor receptor 2 binding
0.38	GO:0019960	C-X3-C chemokine binding
0.38	GO:0031994	insulin-like growth factor I binding
0.38	GO:0001968	fibronectin binding
0.38	GO:0017134	fibroblast growth factor binding

0.81	GO:0008305	integrin complex
0.57	GO:0035866	alphav-beta3 integrin-PKCalpha complex
0.56	GO:0071133	alpha9-beta1 integrin-ADAM8 complex
0.52	GO:0009897	external side of plasma membrane
0.51	GO:0016324	apical plasma membrane
0.39	GO:0035868	alphav-beta3 integrin-HMGB1 complex
0.38	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex
0.38	GO:0031258	lamellipodium membrane
0.38	GO:0031528	microvillus membrane
0.38	GO:0031527	filopodium membrane

0.37

EC:5.3.4.1

GO:0003756

sp|O54891|LEG6_MOUSE
Galectin-6
Search

0.58

Galectin

0.41	GO:1904977	lymphatic endothelial cell migration
0.40	GO:0098792	xenophagy
0.40	GO:0098586	cellular response to virus
0.36	GO:0070241	positive regulation of activated T cell autonomous cell death
0.35	GO:2001190	positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
0.35	GO:0002519	natural killer cell tolerance induction
0.35	GO:0032834	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response
0.35	GO:2000563	positive regulation of CD4-positive, alpha-beta T cell proliferation
0.35	GO:2000670	positive regulation of dendritic cell apoptotic process
0.35	GO:2001184	positive regulation of interleukin-12 secretion

0.70	GO:0030246	carbohydrate binding
0.59	GO:0016936	galactoside binding
0.39	GO:0005178	integrin binding
0.33	GO:0019899	enzyme binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0043236	laminin binding
0.32	GO:0036094	small molecule binding
0.32	GO:0004871	signal transducer activity
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008144	drug binding

0.50	GO:0005615	extracellular space
0.39	GO:0005829	cytosol
0.35	GO:1903561	extracellular vesicle
0.33	GO:0031410	cytoplasmic vesicle
0.33	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|O54897|GPR27_MOUSE
Probable G-protein coupled receptor 27
Search

0.93	G protein-coupled receptor 173

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.58	GO:0097211	cellular response to gonadotropin-releasing hormone
0.53	GO:2001223	negative regulation of neuron migration

0.72	GO:0004930	G-protein coupled receptor activity
0.55	GO:0016500	protein-hormone receptor activity

0.40	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|O54901|OX2G_MOUSE
OX-2 membrane glycoprotein
Search

CD200

0.91	OX-2 membrane glycoprotein isoform a

0.86	GO:0043031	negative regulation of macrophage activation
0.72	GO:0050776	regulation of immune response
0.51	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.49	GO:0008037	cell recognition
0.48	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

0.49	GO:0050839	cell adhesion molecule binding
0.47	GO:0042803	protein homodimerization activity
0.46	GO:0005102	receptor binding
0.43	GO:0004872	receptor activity

0.50	GO:0005913	cell-cell adherens junction
0.44	GO:0005887	integral component of plasma membrane

sp|O54904|B3GT1_MOUSE
Beta-1,3-galactosyltransferase 1
Search

B3GALT1

0.57	Beta-1,3-galactosyltransferase 1

0.78	GO:0006682	galactosylceramide biosynthetic process
0.74	GO:0006486	protein glycosylation
0.67	GO:0030259	lipid glycosylation
0.62	GO:0009312	oligosaccharide biosynthetic process

0.87	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity
0.77	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity

0.71	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.87

EC:2.4.1.86

GO:0047275

sp|O54905|B3GT2_MOUSE
Beta-1,3-galactosyltransferase 2
Search

B3GALT2

0.55	Hexosyltransferase

0.74	GO:0006486	protein glycosylation
0.60	GO:0006682	galactosylceramide biosynthetic process
0.49	GO:0009312	oligosaccharide biosynthetic process

0.80	GO:0008378	galactosyltransferase activity
0.50	GO:0008194	UDP-glycosyltransferase activity

0.74	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:2.4.1

GO:0008378

sp|O54907|TNF12_MOUSE
Tumor necrosis factor ligand superfamily member 12
Search

TNFSF12

0.97	Tumor necrosis factor ligand superfamily member 12

0.74	GO:0006955	immune response
0.59	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway
0.59	GO:0097191	extrinsic apoptotic signaling pathway
0.56	GO:0045732	positive regulation of protein catabolic process
0.49	GO:0010469	regulation of receptor activity
0.42	GO:0001525	angiogenesis
0.40	GO:0030154	cell differentiation
0.39	GO:0043542	endothelial cell migration
0.39	GO:0001938	positive regulation of endothelial cell proliferation
0.39	GO:0033209	tumor necrosis factor-mediated signaling pathway

0.83	GO:0005164	tumor necrosis factor receptor binding
0.51	GO:0005125	cytokine activity

0.55	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0005576	extracellular region
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|O54908|DKK1_MOUSE
Dickkopf-related protein 1
Search

DKK1

0.94	Dickkopf WNT-signaling pathway inhibitor 1

0.79	GO:0030178	negative regulation of Wnt signaling pathway
0.67	GO:0007275	multicellular organism development
0.64	GO:1904711	regulation of Wnt-Frizzled-LRP5/6 complex assembly
0.63	GO:0060828	regulation of canonical Wnt signaling pathway
0.62	GO:0042662	negative regulation of mesodermal cell fate specification
0.62	GO:0003307	regulation of Wnt signaling pathway involved in heart development
0.61	GO:0042663	regulation of endodermal cell fate specification
0.61	GO:2000726	negative regulation of cardiac muscle cell differentiation
0.61	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation
0.60	GO:1901321	positive regulation of heart induction

0.68	GO:0039706	co-receptor binding
0.60	GO:0048019	receptor antagonist activity
0.59	GO:0050750	low-density lipoprotein particle receptor binding
0.35	GO:0008083	growth factor activity
0.35	GO:0004692	cGMP-dependent protein kinase activity
0.34	GO:0004871	signal transducer activity
0.33	GO:0004190	aspartic-type endopeptidase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding

0.64	GO:0005576	extracellular region
0.43	GO:0005886	plasma membrane
0.36	GO:0031901	early endosome membrane
0.30	GO:0016021	integral component of membrane

0.35

EC:2.7.11.12

GO:0004692

tr|O54909|O54909_MOUSE
Cis-retinol androgen dehydrogenase 1
Search

0.94	Retinol dehydrogenase similar protein 2

0.50	GO:0055114	oxidation-reduction process
0.49	GO:0001523	retinoid metabolic process
0.44	GO:0034754	cellular hormone metabolic process
0.43	GO:0016102	diterpenoid biosynthetic process
0.43	GO:0008202	steroid metabolic process
0.39	GO:0072330	monocarboxylic acid biosynthetic process
0.38	GO:0034308	primary alcohol metabolic process
0.37	GO:0017144	drug metabolic process
0.34	GO:0042446	hormone biosynthetic process
0.34	GO:0042447	hormone catabolic process

0.55	GO:0004745	retinol dehydrogenase activity
0.44	GO:0016229	steroid dehydrogenase activity
0.37	GO:0042803	protein homodimerization activity
0.34	GO:0009055	electron transfer activity

0.41	GO:0005783	endoplasmic reticulum
0.37	GO:0031090	organelle membrane
0.37	GO:0044446	intracellular organelle part
0.36	GO:0043233	organelle lumen
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0005769	early endosome
0.35	GO:0098805	whole membrane
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.32	GO:0043232	intracellular non-membrane-bounded organelle

0.55

EC:1.1.1.105

GO:0004745

sp|O54910|IKBE_MOUSE
NF-kappa-B inhibitor epsilon
Search

NFKBIE

0.97	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon

0.54	GO:0042942	D-serine transport
0.45	GO:1901533	negative regulation of hematopoietic progenitor cell differentiation
0.42	GO:0009615	response to virus
0.41	GO:0042994	cytoplasmic sequestering of transcription factor
0.38	GO:0045892	negative regulation of transcription, DNA-templated
0.37	GO:0055085	transmembrane transport
0.35	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0009116	nucleoside metabolic process
0.33	GO:0016310	phosphorylation
0.33	GO:0007219	Notch signaling pathway

0.39	GO:0005515	protein binding
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0016301	kinase activity
0.33	GO:0005216	ion channel activity
0.32	GO:0004519	endonuclease activity

0.78	GO:0001650	fibrillar center
0.64	GO:0005829	cytosol
0.48	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

sp|O54915|NR1I2_MOUSE
Nuclear receptor subfamily 1 group I member 2
Search

NR1I2

0.93	Nuclear receptor subfamily 1 group I member 2

0.77	GO:0043401	steroid hormone mediated signaling pathway
0.68	GO:0030522	intracellular receptor signaling pathway
0.67	GO:0042738	exogenous drug catabolic process
0.62	GO:0046618	drug export
0.61	GO:0006366	transcription by RNA polymerase II
0.59	GO:0042908	xenobiotic transport
0.58	GO:0006805	xenobiotic metabolic process
0.58	GO:0045944	positive regulation of transcription by RNA polymerase II
0.56	GO:0045892	negative regulation of transcription, DNA-templated
0.40	GO:0009636	response to toxic substance

0.78	GO:0003707	steroid hormone receptor activity
0.70	GO:0004879	nuclear receptor activity
0.62	GO:0043565	sequence-specific DNA binding
0.61	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.60	GO:0008270	zinc ion binding
0.59	GO:0001012	RNA polymerase II regulatory region DNA binding
0.56	GO:0003690	double-stranded DNA binding
0.44	GO:0008144	drug binding
0.37	GO:0003713	transcription coactivator activity
0.36	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.59	GO:0045111	intermediate filament cytoskeleton
0.54	GO:0043233	organelle lumen
0.48	GO:0044446	intracellular organelle part
0.39	GO:0005829	cytosol

sp|O54916|REPS1_MOUSE
RalBP1-associated Eps domain-containing protein 1
Search

REPS1

0.94	RalBP1-associated Eps domain-containing protein 1

0.72

GO:0006898

receptor-mediated endocytosis

0.70	GO:0005509	calcium ion binding
0.51	GO:0017124	SH3 domain binding

0.51	GO:0005905	clathrin-coated pit
0.41	GO:0005886	plasma membrane

sp|O54917|E2F6_MOUSE
Transcription factor E2F6
Search

E2F6

0.93	Transcription factor E2F6 isoform B

0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0000082	G1/S transition of mitotic cell cycle
0.49	GO:0048519	negative regulation of biological process
0.47	GO:1990086	lens fiber cell apoptotic process
0.45	GO:1903670	regulation of sprouting angiogenesis
0.45	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.45	GO:1902680	positive regulation of RNA biosynthetic process

0.67	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.48	GO:0001047	core promoter binding
0.42	GO:0008134	transcription factor binding
0.35	GO:0051539	4 iron, 4 sulfur cluster binding
0.35	GO:0003714	transcription corepressor activity
0.33	GO:0016740	transferase activity
0.32	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

0.74	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.50	GO:0034708	methyltransferase complex
0.47	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.34	GO:0032993	protein-DNA complex
0.34	GO:0005694	chromosome
0.32	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016740

sp|O54918|B2L11_MOUSE
Bcl-2-like protein 11
Search

sp|O54926|SIVA_MOUSE
Apoptosis regulatory protein Siva
Search

SIVA1

0.91	SIVA1 apoptosis inducing factor

0.85	GO:0097191	extrinsic apoptotic signaling pathway
0.64	GO:0030260	entry into host cell
0.61	GO:0019058	viral life cycle

0.88	GO:0005175	CD27 receptor binding
0.83	GO:0104005	hijacked molecular function
0.77	GO:0005164	tumor necrosis factor receptor binding

0.70

GO:0005654

nucleoplasm

sp|O54927|WSB1_MOUSE
WD repeat and SOCS box-containing protein 1
Search

WSB1

0.96	WD repeat and SOCS box-containing protein 1

0.65	GO:0016567	protein ubiquitination
0.59	GO:0035556	intracellular signal transduction
0.35	GO:0043687	post-translational protein modification

0.38	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0005515	protein binding

0.43

GO:0005622

intracellular

0.38

GO:0004842

sp|O54928|SOCS5_MOUSE
Suppressor of cytokine signaling 5
Search

SOCS5

0.95	Suppressor of cytokine signaling 5

0.82	GO:0007173	epidermal growth factor receptor signaling pathway
0.82	GO:0007259	JAK-STAT cascade
0.82	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.68	GO:0016567	protein ubiquitination
0.60	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity
0.60	GO:0097699	vascular endothelial cell response to fluid shear stress
0.58	GO:0045629	negative regulation of T-helper 2 cell differentiation
0.58	GO:0045627	positive regulation of T-helper 1 cell differentiation
0.58	GO:0071638	negative regulation of monocyte chemotactic protein-1 production
0.57	GO:0071404	cellular response to low-density lipoprotein particle stimulus

0.57	GO:0030971	receptor tyrosine kinase binding
0.56	GO:0005154	epidermal growth factor receptor binding
0.47	GO:0004860	protein kinase inhibitor activity

0.45

GO:0005622

intracellular

sp|O54929|WSB2_MOUSE
WD repeat and SOCS box-containing protein 2
Search

WSB2

0.92	LOW QUALITY PROTEIN: WD repeat and SOCS box-containing protein 2

0.68	GO:0016567	protein ubiquitination
0.61	GO:0035556	intracellular signal transduction
0.35	GO:0043687	post-translational protein modification
0.34	GO:0006261	DNA-dependent DNA replication
0.34	GO:0006281	DNA repair

0.35	GO:0003689	DNA clamp loader activity
0.32	GO:0046872	metal ion binding

0.44	GO:0005622	intracellular
0.33	GO:0043234	protein complex
0.33	GO:0043228	non-membrane-bounded organelle
0.33	GO:0044422	organelle part
0.33	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

sp|O54931|AKAP2_MOUSE
A-kinase anchor protein 2
Search

AKAP2

0.93	A-kinase anchor protein 2

0.57	GO:0016310	phosphorylation
0.47	GO:0008360	regulation of cell shape
0.42	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.41	GO:0007015	actin filament organization
0.39	GO:0051291	protein heterooligomerization
0.38	GO:0008104	protein localization

0.59	GO:0016301	kinase activity
0.43	GO:0051018	protein kinase A binding
0.38	GO:0019904	protein domain specific binding

0.35	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|O54940|BNIP2_MOUSE
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2
Search

BNIP2

0.92	BCL2/adenovirus E1B protein-interacting protein 2 isoform A

0.57	GO:0006915	apoptotic process
0.55	GO:0045597	positive regulation of cell differentiation
0.54	GO:0001824	blastocyst development
0.53	GO:0051057	positive regulation of small GTPase mediated signal transduction
0.52	GO:0007098	centrosome cycle
0.52	GO:0051146	striated muscle cell differentiation
0.51	GO:0051962	positive regulation of nervous system development
0.51	GO:0043410	positive regulation of MAPK cascade
0.51	GO:0045664	regulation of neuron differentiation
0.46	GO:0051147	regulation of muscle cell differentiation

0.55	GO:0042802	identical protein binding
0.43	GO:0005096	GTPase activator activity
0.42	GO:0005509	calcium ion binding

0.55	GO:0031616	spindle pole centrosome
0.52	GO:0005814	centriole
0.52	GO:0005829	cytosol
0.51	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0005635	nuclear envelope
0.30	GO:0031224	intrinsic component of membrane

sp|O54941|SMCE1_MOUSE
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
Search

SMARCE1

0.91	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

0.81	GO:0043044	ATP-dependent chromatin remodeling
0.53	GO:0031498	chromatin disassembly
0.53	GO:0032986	protein-DNA complex disassembly
0.50	GO:0034728	nucleosome organization
0.48	GO:0022008	neurogenesis
0.47	GO:0045892	negative regulation of transcription, DNA-templated
0.36	GO:0016569	covalent chromatin modification
0.34	GO:0007286	spermatid development
0.34	GO:0007420	brain development
0.34	GO:0006357	regulation of transcription by RNA polymerase II

0.55	GO:0003677	DNA binding
0.54	GO:0016922	ligand-dependent nuclear receptor binding
0.53	GO:0047485	protein N-terminus binding
0.45	GO:0008080	N-acetyltransferase activity
0.41	GO:0003723	RNA binding
0.36	GO:0031491	nucleosome binding
0.35	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0005198	structural molecule activity
0.34	GO:0003713	transcription coactivator activity

0.82	GO:0016514	SWI/SNF complex
0.51	GO:0071565	nBAF complex
0.51	GO:0071564	npBAF complex
0.51	GO:0017053	transcriptional repressor complex
0.47	GO:0005654	nucleoplasm
0.38	GO:0005882	intermediate filament
0.34	GO:0043234	protein complex

0.45

EC:2.3.1

GO:0008080

sp|O54942|CLD5_MOUSE
Claudin-5
Search

0.69

Claudin

0.50	GO:0045216	cell-cell junction organization
0.43	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.43	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.43	GO:0044409	entry into host
0.42	GO:0019058	viral life cycle
0.40	GO:0048856	anatomical structure development
0.40	GO:1901552	positive regulation of endothelial cell development
0.40	GO:0034329	cell junction assembly
0.40	GO:1903140	regulation of establishment of endothelial barrier
0.39	GO:0045471	response to ethanol

0.62	GO:0005198	structural molecule activity
0.50	GO:0104005	hijacked molecular function
0.39	GO:0042802	identical protein binding
0.35	GO:0005254	chloride channel activity

0.81	GO:0005923	bicellular tight junction
0.55	GO:0005886	plasma membrane
0.40	GO:0043220	Schmidt-Lanterman incisure
0.40	GO:0033270	paranode region of axon
0.39	GO:0043227	membrane-bounded organelle
0.38	GO:0043229	intracellular organelle
0.38	GO:0044448	cell cortex part
0.37	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space
0.35	GO:0043228	non-membrane-bounded organelle

sp|O54943|PER2_MOUSE
Period circadian protein homolog 2
Search

PER2

0.91	Period circadian protein like protein 2

0.60	GO:0007623	circadian rhythm
0.59	GO:0051946	regulation of glutamate uptake involved in transmission of nerve impulse
0.57	GO:0042752	regulation of circadian rhythm
0.56	GO:0070345	negative regulation of fat cell proliferation
0.55	GO:0050872	white fat cell differentiation
0.55	GO:0019249	lactate biosynthetic process
0.55	GO:0002931	response to ischemia
0.54	GO:2000678	negative regulation of transcription regulatory region DNA binding
0.53	GO:0031397	negative regulation of protein ubiquitination
0.53	GO:0019229	regulation of vasoconstriction

0.51	GO:0000989	transcription factor activity, transcription factor binding
0.50	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.49	GO:1990226	histone methyltransferase binding
0.49	GO:0001222	transcription corepressor binding
0.47	GO:0042826	histone deacetylase binding
0.47	GO:0036002	pre-mRNA binding
0.47	GO:0035257	nuclear hormone receptor binding
0.46	GO:0001047	core promoter binding
0.45	GO:0019900	kinase binding
0.45	GO:0070063	RNA polymerase binding

0.60	GO:0005634	nucleus
0.51	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0031974	membrane-enclosed lumen
0.39	GO:0005829	cytosol
0.38	GO:0044446	intracellular organelle part
0.36	GO:0043232	intracellular non-membrane-bounded organelle

sp|O54946|DNJB6_MOUSE
DnaJ homolog subfamily B member 6
Search

DNAJB6

0.85	DnaJ like protein subfamily B member 6

0.74	GO:0060715	syncytiotrophoblast cell differentiation involved in labyrinthine layer development
0.72	GO:0060710	chorio-allantoic fusion
0.71	GO:0060717	chorion development
0.67	GO:0090084	negative regulation of inclusion body assembly
0.65	GO:0045109	intermediate filament organization
0.64	GO:0030198	extracellular matrix organization
0.63	GO:0034504	protein localization to nucleus
0.63	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.60	GO:0032781	positive regulation of ATPase activity
0.59	GO:0030036	actin cytoskeleton organization

0.61	GO:0001671	ATPase activator activity
0.58	GO:0031072	heat shock protein binding
0.58	GO:0051087	chaperone binding
0.55	GO:0051082	unfolded protein binding
0.51	GO:0042802	identical protein binding
0.50	GO:0044183	protein binding involved in protein folding
0.47	GO:0003677	DNA binding
0.39	GO:0003735	structural constituent of ribosome

0.70	GO:0048471	perinuclear region of cytoplasm
0.68	GO:0030018	Z disc
0.60	GO:0005634	nucleus
0.53	GO:0005829	cytosol
0.51	GO:0031974	membrane-enclosed lumen
0.46	GO:0044446	intracellular organelle part
0.38	GO:0005840	ribosome
0.30	GO:0016020	membrane

sp|O54949|NLK_MOUSE
Serine/threonine-protein kinase NLK
Search

NLK

0.58	Mitogen-activated protein kinase

0.78	GO:0000165	MAPK cascade
0.56	GO:0030111	regulation of Wnt signaling pathway
0.56	GO:0018107	peptidyl-threonine phosphorylation
0.55	GO:0042501	serine phosphorylation of STAT protein
0.54	GO:0007179	transforming growth factor beta receptor signaling pathway
0.52	GO:0050821	protein stabilization
0.50	GO:0046777	protein autophosphorylation
0.49	GO:0009968	negative regulation of signal transduction
0.46	GO:0030901	midbrain development
0.45	GO:0009967	positive regulation of signal transduction

0.79	GO:0004707	MAP kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0042169	SH2 domain binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0031625	ubiquitin protein ligase binding
0.49	GO:0008134	transcription factor binding
0.44	GO:0000287	magnesium ion binding
0.33	GO:0016853	isomerase activity
0.33	GO:0051539	4 iron, 4 sulfur cluster binding

0.45	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.79	EC:2.7.11.24	GO:0004707
0.79	KEGG:R00162	GO:0004707

sp|O54950|AAKG1_MOUSE
5'-AMP-activated protein kinase subunit gamma-1
Search

PRKAG1

0.96	5'-AMP-activated protein kinase gamma-1 non-catalytic subunit variant 1

0.55	GO:0016310	phosphorylation
0.51	GO:0010604	positive regulation of macromolecule metabolic process
0.50	GO:0051170	nuclear import
0.46	GO:0036211	protein modification process
0.44	GO:0006110	regulation of glycolytic process
0.43	GO:0044267	cellular protein metabolic process
0.42	GO:0010468	regulation of gene expression
0.42	GO:0010799	regulation of peptidyl-threonine phosphorylation
0.42	GO:0019217	regulation of fatty acid metabolic process
0.42	GO:0033674	positive regulation of kinase activity

0.58	GO:0016301	kinase activity
0.54	GO:0019901	protein kinase binding
0.46	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.44	GO:0008607	phosphorylase kinase regulator activity
0.44	GO:0140096	catalytic activity, acting on a protein
0.44	GO:0043531	ADP binding
0.44	GO:0008603	cAMP-dependent protein kinase regulator activity
0.43	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.42	GO:0016208	AMP binding
0.42	GO:0030295	protein kinase activator activity

0.47	GO:0031588	nucleotide-activated protein kinase complex
0.45	GO:0005634	nucleus
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:0034708	methyltransferase complex
0.38	GO:0005615	extracellular space
0.37	GO:0044446	intracellular organelle part
0.37	GO:1903561	extracellular vesicle
0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.46

GO:0016773

sp|O54951|SEM6B_MOUSE
Semaphorin-6B
Search

SEMA6B

0.91	Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba

0.45	GO:2001224	positive regulation of neuron migration
0.44	GO:0051642	centrosome localization
0.43	GO:0001764	neuron migration
0.43	GO:0071526	semaphorin-plexin signaling pathway
0.42	GO:0007411	axon guidance
0.36	GO:1903671	negative regulation of sprouting angiogenesis
0.34	GO:0006915	apoptotic process

0.60	GO:0030215	semaphorin receptor binding
0.40	GO:0004888	transmembrane signaling receptor activity
0.35	GO:0042802	identical protein binding

0.45	GO:0005887	integral component of plasma membrane
0.34	GO:0030424	axon

sp|O54956|DPOE2_MOUSE
DNA polymerase epsilon subunit 2
Search

POLE2

0.83	DNA polymerase epsilon subunit

0.67	GO:0071897	DNA biosynthetic process
0.67	GO:0006261	DNA-dependent DNA replication
0.49	GO:0006301	postreplication repair
0.35	GO:0000082	G1/S transition of mitotic cell cycle
0.35	GO:0000723	telomere maintenance
0.34	GO:0019725	cellular homeostasis
0.33	GO:0060285	cilium-dependent cell motility
0.33	GO:0070286	axonemal dynein complex assembly

0.71	GO:0003887	DNA-directed DNA polymerase activity
0.55	GO:0003677	DNA binding
0.33	GO:0005515	protein binding

0.79	GO:0008622	epsilon DNA polymerase complex
0.52	GO:0016604	nuclear body
0.34	GO:0005680	anaphase-promoting complex
0.31	GO:0005737	cytoplasm

0.71

GO:0003887

sp|O54957|LAT_MOUSE
Linker for activation of T-cells family member 1
Search

LAT

0.97	Linker for activation of T cells

0.65	GO:0019722	calcium-mediated signaling
0.64	GO:0007265	Ras protein signal transduction
0.64	GO:0002260	lymphocyte homeostasis
0.62	GO:0007229	integrin-mediated signaling pathway
0.62	GO:0045860	positive regulation of protein kinase activity
0.60	GO:0050863	regulation of T cell activation
0.60	GO:0006954	inflammatory response
0.60	GO:0009967	positive regulation of signal transduction
0.59	GO:0006955	immune response
0.46	GO:0002448	mast cell mediated immunity

0.66	GO:0005070	SH3/SH2 adaptor activity
0.61	GO:0019901	protein kinase binding
0.40	GO:0005057	signal transducer activity, downstream of receptor

0.69	GO:0001772	immunological synapse
0.61	GO:0008180	COP9 signalosome
0.58	GO:0005911	cell-cell junction
0.57	GO:0005794	Golgi apparatus
0.46	GO:0042629	mast cell granule
0.37	GO:0005887	integral component of plasma membrane

sp|O54962|BAF_MOUSE
Barrier-to-autointegration factor
Search

BANF1

0.94	Barrier-to-autointegration factor B

0.51	GO:0045071	negative regulation of viral genome replication
0.36	GO:0030717	karyosome formation
0.36	GO:0075713	establishment of integrated proviral latency
0.35	GO:0015074	DNA integration
0.35	GO:0007077	mitotic nuclear envelope disassembly
0.35	GO:0010951	negative regulation of endopeptidase activity
0.35	GO:0007084	mitotic nuclear envelope reassembly
0.34	GO:0030261	chromosome condensation
0.34	GO:0051169	nuclear transport
0.34	GO:0009615	response to virus

0.55	GO:0097726	LEM domain binding
0.55	GO:0003677	DNA binding
0.51	GO:0047485	protein N-terminus binding
0.50	GO:0008022	protein C-terminus binding
0.47	GO:0042803	protein homodimerization activity
0.45	GO:0019899	enzyme binding
0.36	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.32	GO:0004721	phosphoprotein phosphatase activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding

0.45	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.40	GO:0005635	nuclear envelope
0.38	GO:0005694	chromosome
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.32

GO:0004721

sp|O54965|RNF13_MOUSE
E3 ubiquitin-protein ligase RNF13
Search

RNF13

0.92	RING finger protein 13

0.64	GO:0051865	protein autoubiquitination
0.37	GO:0000209	protein polyubiquitination
0.37	GO:0045786	negative regulation of cell cycle

0.59	GO:0061630	ubiquitin protein ligase activity
0.47	GO:0008270	zinc ion binding

0.63	GO:0031902	late endosome membrane
0.62	GO:0005765	lysosomal membrane
0.58	GO:0005654	nucleoplasm
0.57	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|O54967|ACK1_MOUSE
Activated CDC42 kinase 1
Search

TNK2

0.92	Tyrosine kinase non-receptor

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.55	GO:0007165	signal transduction
0.53	GO:2000369	regulation of clathrin-dependent endocytosis
0.51	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.46	GO:0046777	protein autophosphorylation
0.45	GO:0045087	innate immune response
0.45	GO:0016477	cell migration
0.45	GO:0042127	regulation of cell proliferation
0.43	GO:0030154	cell differentiation
0.38	GO:0006897	endocytosis

0.76	GO:0004713	protein tyrosine kinase activity
0.72	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0005154	epidermal growth factor receptor binding
0.49	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0042802	identical protein binding
0.40	GO:0050699	WW domain binding
0.38	GO:0004674	protein serine/threonine kinase activity

0.55	GO:0070436	Grb2-EGFR complex
0.50	GO:0005905	clathrin-coated pit
0.50	GO:0030136	clathrin-coated vesicle
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.43	GO:0005634	nucleus
0.40	GO:0005912	adherens junction
0.39	GO:0030659	cytoplasmic vesicle membrane
0.39	GO:0005768	endosome
0.38	GO:0030426	growth cone
0.38	GO:0043025	neuronal cell body

0.76

EC:2.7.10

GO:0004713

sp|O54972|MTG16_MOUSE
Protein CBFA2T3
Search

CBFA2T3

0.95	Core-binding factor, runt domain, alpha subunit 2; translocated to, 3

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.55	GO:0045820	negative regulation of glycolytic process
0.55	GO:1903715	regulation of aerobic respiration
0.54	GO:0030851	granulocyte differentiation
0.53	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.52	GO:0001666	response to hypoxia
0.50	GO:0008285	negative regulation of cell proliferation
0.38	GO:0045599	negative regulation of fat cell differentiation
0.37	GO:0045444	fat cell differentiation
0.37	GO:0051101	regulation of DNA binding

0.81	GO:0003714	transcription corepressor activity
0.61	GO:0003700	DNA binding transcription factor activity
0.37	GO:0003682	chromatin binding
0.36	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding
0.34	GO:0003676	nucleic acid binding

0.51	GO:0005654	nucleoplasm
0.38	GO:0016363	nuclear matrix
0.36	GO:0005730	nucleolus
0.36	GO:0005794	Golgi apparatus
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0031984	organelle subcompartment
0.34	GO:0017053	transcriptional repressor complex

sp|O54974|LEG7_MOUSE
Galectin-7
Search

0.65

Galectin

0.81	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.40	GO:0006915	apoptotic process
0.33	GO:0006508	proteolysis

0.70	GO:0030246	carbohydrate binding
0.35	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.34	GO:0005509	calcium ion binding

0.69	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.37	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|O54982|KCNU1_MOUSE
Potassium channel subfamily U member 1
Search

0.79	Calcium-activated potassium channel

0.71	GO:0006813	potassium ion transport
0.60	GO:0034220	ion transmembrane transport
0.40	GO:0034765	regulation of ion transmembrane transport
0.40	GO:0034465	response to carbon monoxide
0.40	GO:0060083	smooth muscle contraction involved in micturition
0.39	GO:0045794	negative regulation of cell volume
0.38	GO:0030007	cellular potassium ion homeostasis
0.38	GO:0051592	response to calcium ion
0.38	GO:0001666	response to hypoxia
0.38	GO:0050821	protein stabilization

0.77	GO:0060072	large conductance calcium-activated potassium channel activity
0.71	GO:0005249	voltage-gated potassium channel activity
0.37	GO:0003779	actin binding
0.34	GO:0042802	identical protein binding
0.33	GO:0032403	protein complex binding
0.33	GO:0046872	metal ion binding
0.33	GO:0046983	protein dimerization activity

0.71	GO:0008076	voltage-gated potassium channel complex
0.38	GO:0005901	caveola
0.38	GO:0016324	apical plasma membrane
0.36	GO:0043195	terminal bouton
0.36	GO:0009897	external side of plasma membrane
0.36	GO:0045211	postsynaptic membrane
0.35	GO:0070062	extracellular exosome
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0048787	presynaptic active zone membrane
0.33	GO:0043025	neuronal cell body

sp|O54983|CRYM_MOUSE
Ketimine reductase mu-crystallin
Search

CRYM

0.97	Thiomorpholine-carboxylate dehydrogenase

0.83	GO:0042403	thyroid hormone metabolic process
0.82	GO:0070327	thyroid hormone transport
0.77	GO:0007605	sensory perception of sound
0.73	GO:0000122	negative regulation of transcription by RNA polymerase II
0.45	GO:0055114	oxidation-reduction process
0.40	GO:0033280	response to vitamin D
0.38	GO:0006839	mitochondrial transport
0.38	GO:0006554	lysine catabolic process
0.37	GO:0009725	response to hormone

0.85	GO:0070324	thyroid hormone binding
0.76	GO:0003714	transcription corepressor activity
0.71	GO:0042803	protein homodimerization activity
0.66	GO:0050661	NADP binding
0.58	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
0.57	GO:0047127	thiomorpholine-carboxylate dehydrogenase activity
0.44	GO:0008473	ornithine cyclodeaminase activity
0.39	GO:0005212	structural constituent of eye lens

0.65	GO:0005829	cytosol
0.57	GO:0005634	nucleus
0.56	GO:0005739	mitochondrion
0.41	GO:0070062	extracellular exosome
0.39	GO:0031907	microbody lumen
0.38	GO:0044439	peroxisomal part
0.30	GO:0031224	intrinsic component of membrane

0.58	EC:1.4.1	GO:0016639
0.44	KEGG:R00671	GO:0008473

sp|O54984|ASNA_MOUSE
ATPase Asna1
Search

ASNA1

0.66	Arsenical pump-driving ATPase

0.77	GO:0045048	protein insertion into ER membrane
0.45	GO:0007416	synapse assembly
0.35	GO:0036498	IRE1-mediated unfolded protein response
0.34	GO:0015700	arsenite transport

0.61	GO:0016887	ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.34	GO:0015105	arsenite transmembrane transporter activity
0.33	GO:0005515	protein binding

0.70	GO:0005783	endoplasmic reticulum
0.48	GO:0005730	nucleolus
0.37	GO:0070062	extracellular exosome
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.30	GO:0044425	membrane part

0.61

GO:0016887

sp|O54988|SLK_MOUSE
STE20-like serine/threonine-protein kinase
Search

SLK

0.94	STE20 like kinase

0.77	GO:0051893	regulation of focal adhesion assembly
0.75	GO:0031122	cytoplasmic microtubule organization
0.72	GO:0046777	protein autophosphorylation
0.70	GO:0030334	regulation of cell migration
0.68	GO:0042981	regulation of apoptotic process
0.55	GO:0031098	stress-activated protein kinase signaling cascade
0.54	GO:0032147	activation of protein kinase activity
0.52	GO:0007346	regulation of mitotic cell cycle
0.47	GO:0023014	signal transduction by protein phosphorylation

0.73	GO:0045296	cadherin binding
0.70	GO:0004674	protein serine/threonine kinase activity
0.68	GO:0042803	protein homodimerization activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0031252	cell leading edge
0.71	GO:0048471	perinuclear region of cytoplasm

0.70

GO:0004674

sp|O54990|PROM1_MOUSE
Prominin-1
Search

PROM1

0.94

Fudenine

0.64	GO:0072139	glomerular parietal epithelial cell differentiation
0.64	GO:2000768	positive regulation of nephron tubule epithelial cell differentiation
0.61	GO:0072112	glomerular visceral epithelial cell differentiation
0.61	GO:0060219	camera-type eye photoreceptor cell differentiation
0.60	GO:0045494	photoreceptor cell maintenance
0.45	GO:0010842	retina layer formation

0.58	GO:0042805	actinin binding
0.57	GO:0045296	cadherin binding

0.62	GO:0042622	photoreceptor outer segment membrane
0.59	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.57	GO:0070062	extracellular exosome
0.54	GO:0009986	cell surface
0.52	GO:0005783	endoplasmic reticulum
0.46	GO:0071914	prominosome
0.44	GO:0005902	microvillus
0.44	GO:0016324	apical plasma membrane
0.44	GO:0032420	stereocilium
0.44	GO:0005903	brush border

sp|O54991|CNTP1_MOUSE
Contactin-associated protein 1
Search

CNTNAP1

0.82	Contactin associated protein like 5

0.85	GO:0030913	paranodal junction assembly
0.70	GO:0002175	protein localization to paranode region of axon
0.69	GO:0098870	action potential propagation
0.68	GO:0022010	central nervous system myelination
0.68	GO:0071205	protein localization to juxtaparanode region of axon
0.68	GO:0050884	neuromuscular process controlling posture
0.66	GO:0022011	myelination in peripheral nervous system
0.66	GO:0050885	neuromuscular process controlling balance
0.66	GO:0019226	transmission of nerve impulse
0.61	GO:0048812	neuron projection morphogenesis

0.41	GO:0017124	SH3 domain binding
0.37	GO:0005070	SH3/SH2 adaptor activity
0.35	GO:0004872	receptor activity

0.84	GO:0033270	paranode region of axon
0.63	GO:0043209	myelin sheath
0.60	GO:0008076	voltage-gated potassium channel complex
0.44	GO:0033010	paranodal junction

sp|O54992|MAPK5_MOUSE
MAP kinase-activated protein kinase 5
Search

MAPKAPK5

0.97	Mitogen-activated protein kinase-activated protein kinase 5

0.63	GO:0006468	protein phosphorylation
0.55	GO:0090400	stress-induced premature senescence
0.54	GO:0007265	Ras protein signal transduction
0.54	GO:1904355	positive regulation of telomere capping
0.53	GO:0051973	positive regulation of telomerase activity
0.53	GO:0032212	positive regulation of telomere maintenance via telomerase
0.48	GO:0032007	negative regulation of TOR signaling
0.47	GO:0006417	regulation of translation
0.46	GO:0018209	peptidyl-serine modification
0.43	GO:0007166	cell surface receptor signaling pathway

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0002039	p53 binding
0.50	GO:0051019	mitogen-activated protein kinase binding
0.46	GO:0005516	calmodulin binding
0.41	GO:0004871	signal transducer activity
0.34	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.34	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors

0.46	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.40	GO:0032156	septin cytoskeleton
0.36	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.34

EC:1.2.1

GO:0016620

sp|O54998|FKBP7_MOUSE
Peptidyl-prolyl cis-trans isomerase FKBP7
Search

FKBP7

0.44	Peptidyl-prolyl cis-trans isomerase FKBP7

0.66	GO:0000413	protein peptidyl-prolyl isomerization
0.64	GO:0061077	chaperone-mediated protein folding

0.70	GO:0005509	calcium ion binding
0.69	GO:0005528	FK506 binding
0.67	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.53	GO:0005515	protein binding

0.76

GO:0005788

endoplasmic reticulum lumen

0.67

EC:5.2.1.8

GO:0003755

sp|O55003|BNIP3_MOUSE
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
Search

BNIP3

0.66	BCL2-interacting protein 3

0.79	GO:0043065	positive regulation of apoptotic process
0.59	GO:0035694	mitochondrial protein catabolic process
0.57	GO:0097345	mitochondrial outer membrane permeabilization
0.56	GO:0016239	positive regulation of macroautophagy
0.56	GO:0071456	cellular response to hypoxia
0.55	GO:0010821	regulation of mitochondrion organization
0.54	GO:0045837	negative regulation of membrane potential
0.54	GO:0071279	cellular response to cobalt ion
0.53	GO:0060548	negative regulation of cell death
0.53	GO:0008626	granzyme-mediated apoptotic signaling pathway

0.52	GO:0042803	protein homodimerization activity
0.51	GO:0046982	protein heterodimerization activity
0.47	GO:0005521	lamin binding
0.46	GO:0051020	GTPase binding

0.62	GO:0005740	mitochondrial envelope
0.53	GO:0031968	organelle outer membrane
0.52	GO:0005635	nuclear envelope
0.50	GO:0014069	postsynaptic density
0.47	GO:0031301	integral component of organelle membrane
0.46	GO:0005783	endoplasmic reticulum
0.45	GO:0016607	nuclear speck
0.37	GO:0030425	dendrite
0.35	GO:0005829	cytosol

sp|O55013|TPPC3_MOUSE
Trafficking protein particle complex subunit 3
Search

TRAPPC3

0.77	Trafficking protein particle complex subunit

0.75	GO:0048193	Golgi vesicle transport
0.47	GO:0046907	intracellular transport
0.35	GO:0006901	vesicle coating
0.35	GO:0006903	vesicle targeting
0.33	GO:0006461	protein complex assembly
0.33	GO:0065009	regulation of molecular function

0.35

GO:0017112

Rab guanyl-nucleotide exchange factor activity

0.81	GO:0030008	TRAPP complex
0.66	GO:0005794	Golgi apparatus
0.65	GO:0005783	endoplasmic reticulum
0.48	GO:0098588	bounding membrane of organelle
0.48	GO:0005829	cytosol
0.47	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

sp|O55017|CAC1B_MOUSE
Voltage-dependent N-type calcium channel subunit alpha-1B
Search

CACNA1B

0.86	Voltage-dependent N-type calcium channel subunit alpha

0.77	GO:0034765	regulation of ion transmembrane transport
0.77	GO:0070588	calcium ion transmembrane transport
0.51	GO:0048265	response to pain
0.49	GO:0008016	regulation of heart contraction
0.49	GO:0008217	regulation of blood pressure
0.49	GO:0051924	regulation of calcium ion transport
0.49	GO:0099643	signal release from synapse
0.49	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.49	GO:0007626	locomotory behavior
0.47	GO:0006836	neurotransmitter transport

0.81	GO:0005245	voltage-gated calcium channel activity
0.57	GO:0005509	calcium ion binding
0.49	GO:0008022	protein C-terminus binding
0.37	GO:0051721	protein phosphatase 2A binding
0.36	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0005891	voltage-gated calcium channel complex
0.49	GO:0043025	neuronal cell body
0.48	GO:0030425	dendrite
0.48	GO:0098793	presynapse
0.36	GO:0044306	neuron projection terminus
0.35	GO:0009986	cell surface
0.34	GO:0043234	protein complex

sp|O55022|PGRC1_MOUSE
Membrane-associated progesterone receptor component 1
Search

PGRMC1

0.97	Membrane-associated progesterone receptor component 1

0.47	GO:1903538	regulation of meiotic cell cycle process involved in oocyte maturation
0.40	GO:1903537	meiotic cell cycle process involved in oocyte maturation
0.37	GO:0099563	modification of synaptic structure
0.36	GO:0043312	neutrophil degranulation
0.36	GO:1905809	negative regulation of synapse organization
0.36	GO:1903078	positive regulation of protein localization to plasma membrane
0.36	GO:0008306	associative learning
0.36	GO:0007613	memory
0.35	GO:0007411	axon guidance
0.34	GO:0071310	cellular response to organic substance

0.45	GO:0005496	steroid binding
0.44	GO:0020037	heme binding
0.36	GO:0005515	protein binding
0.34	GO:0003707	steroid hormone receptor activity
0.33	GO:0042020	interleukin-23 receptor activity
0.32	GO:0005509	calcium ion binding
0.32	GO:0016301	kinase activity

0.49	GO:0012505	endomembrane system
0.42	GO:0044428	nuclear part
0.40	GO:0031967	organelle envelope
0.40	GO:0070062	extracellular exosome
0.40	GO:0031984	organelle subcompartment
0.39	GO:0098588	bounding membrane of organelle
0.39	GO:0042585	germinal vesicle
0.39	GO:0106003	amyloid-beta complex
0.39	GO:1990385	meiotic spindle midzone
0.38	GO:0030496	midbody

sp|O55023|IMPA1_MOUSE
Inositol monophosphatase 1
Search

IMPA1

0.41	Inositol monophosphatase 1

0.80	GO:0006021	inositol biosynthetic process
0.79	GO:0046855	inositol phosphate dephosphorylation
0.75	GO:0046854	phosphatidylinositol phosphorylation
0.50	GO:0006661	phosphatidylinositol biosynthetic process
0.44	GO:0007165	signal transduction
0.35	GO:0010226	response to lithium ion

0.79	GO:0008934	inositol monophosphate 1-phosphatase activity
0.79	GO:0052832	inositol monophosphate 3-phosphatase activity
0.79	GO:0052833	inositol monophosphate 4-phosphatase activity
0.58	GO:0031403	lithium ion binding
0.49	GO:0042803	protein homodimerization activity
0.49	GO:0030145	manganese ion binding
0.45	GO:0000287	magnesium ion binding

0.38	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0043025	neuronal cell body
0.34	GO:0030424	axon
0.30	GO:0016020	membrane

0.79

EC:3.1.3.25

GO:0008934

sp|O55026|ENTP2_MOUSE
Ectonucleoside triphosphate diphosphohydrolase 2
Search

ENTPD2

0.96	Ectonucleoside triphosphate diphosphohydrolase 2

0.58	GO:0009137	purine nucleoside diphosphate catabolic process
0.57	GO:0009191	ribonucleoside diphosphate catabolic process
0.54	GO:0030168	platelet activation
0.48	GO:0007186	G-protein coupled receptor signaling pathway
0.48	GO:0009179	purine ribonucleoside diphosphate metabolic process
0.41	GO:0045471	response to ethanol
0.41	GO:0071405	cellular response to methanol
0.40	GO:0046688	response to copper ion
0.36	GO:0034656	nucleobase-containing small molecule catabolic process
0.36	GO:0035457	cellular response to interferon-alpha

0.53	GO:0017110	nucleoside-diphosphatase activity
0.43	GO:0017111	nucleoside-triphosphatase activity
0.35	GO:1901265	nucleoside phosphate binding
0.35	GO:0005515	protein binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0008144	drug binding
0.35	GO:0036094	small molecule binding
0.34	GO:0043168	anion binding

0.55	GO:0005605	basal lamina
0.41	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.35	GO:0044297	cell body
0.35	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0009986	cell surface
0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.53

EC:3.6.1.6

GO:0017110

sp|O55028|BCKD_MOUSE
[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial
Search

BCKDK

0.96	Branched chain alpha-ketoacid dehydrogenase kinase

0.56	GO:0016310	phosphorylation
0.46	GO:0036211	protein modification process
0.43	GO:0044267	cellular protein metabolic process
0.41	GO:0009083	branched-chain amino acid catabolic process

0.56	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.44	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.46	GO:0005739	mitochondrion
0.41	GO:0045240	dihydrolipoyl dehydrogenase complex
0.39	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.56

EC:2.7

GO:0016772

sp|O55029|COPB2_MOUSE
Coatomer subunit beta'
Search

COPB2

0.63	Coatomer subunit beta'

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.52	GO:1901998	toxin transport
0.47	GO:0030903	notochord development
0.46	GO:0061053	somite development

0.62	GO:0005198	structural molecule activity
0.37	GO:0005080	protein kinase C binding
0.32	GO:0016740	transferase activity

0.75	GO:0030117	membrane coat
0.73	GO:0030663	COPI-coated vesicle membrane
0.67	GO:0000139	Golgi membrane
0.38	GO:0005829	cytosol
0.36	GO:0030133	transport vesicle
0.34	GO:0099503	secretory vesicle
0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016740

sp|O55033|NCK2_MOUSE
Cytoplasmic protein NCK2
Search

NCK2

0.96	NCK adaptor protein 2

0.75	GO:0009967	positive regulation of signal transduction
0.62	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
0.61	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress
0.61	GO:1903898	negative regulation of PERK-mediated unfolded protein response
0.61	GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
0.59	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.59	GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.59	GO:1905898	positive regulation of response to endoplasmic reticulum stress
0.58	GO:0030032	lamellipodium assembly
0.57	GO:0042102	positive regulation of T cell proliferation

0.84	GO:0005070	SH3/SH2 adaptor activity
0.55	GO:0097110	scaffold protein binding
0.55	GO:0001784	phosphotyrosine residue binding
0.50	GO:0032403	protein complex binding
0.45	GO:0071074	eukaryotic initiation factor eIF2 binding
0.42	GO:0030971	receptor tyrosine kinase binding
0.42	GO:0004860	protein kinase inhibitor activity
0.42	GO:0045296	cadherin binding
0.41	GO:0046875	ephrin receptor binding
0.39	GO:0019904	protein domain specific binding

0.52	GO:0012506	vesicle membrane
0.50	GO:0005783	endoplasmic reticulum
0.42	GO:0000164	protein phosphatase type 1 complex
0.39	GO:0005911	cell-cell junction
0.39	GO:0014069	postsynaptic density
0.37	GO:0005840	ribosome
0.35	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane

sp|O55038|CXL13_MOUSE
C-X-C motif chemokine 13
Search

CXCL13

0.69	C-X-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.75	GO:0072676	lymphocyte migration
0.74	GO:0006955	immune response
0.72	GO:0006952	defense response
0.71	GO:2000545	negative regulation of endothelial cell chemotaxis to fibroblast growth factor
0.71	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin
0.70	GO:0033625	positive regulation of integrin activation
0.68	GO:0010469	regulation of receptor activity
0.68	GO:0010820	positive regulation of T cell chemotaxis
0.68	GO:0048535	lymph node development

0.84	GO:0008009	chemokine activity
0.82	GO:0031724	CXCR5 chemokine receptor binding
0.70	GO:0031735	CCR10 chemokine receptor binding
0.69	GO:0048248	CXCR3 chemokine receptor binding
0.66	GO:0017134	fibroblast growth factor binding
0.63	GO:0008201	heparin binding
0.57	GO:0046982	protein heterodimerization activity

0.66	GO:0005576	extracellular region
0.30	GO:0005623	cell

sp|O55040|NMUR1_MOUSE
Neuromedin-U receptor 1
Search

NMUR1

0.94	Neuromedin-U receptor 1

0.80	GO:0007218	neuropeptide signaling pathway
0.59	GO:0010518	positive regulation of phospholipase activity
0.58	GO:0048016	inositol phosphate-mediated signaling
0.57	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.56	GO:0019722	calcium-mediated signaling
0.56	GO:1900274	regulation of phospholipase C activity
0.54	GO:1903955	positive regulation of protein targeting to mitochondrion
0.54	GO:0006939	smooth muscle contraction
0.53	GO:0006821	chloride transport
0.53	GO:0006816	calcium ion transport

0.86	GO:0001607	neuromedin U receptor activity
0.62	GO:0042924	neuromedin U binding
0.44	GO:0061778	intracellular chloride channel activity
0.40	GO:0022839	ion gated channel activity
0.40	GO:0008381	mechanosensitive ion channel activity
0.39	GO:0032550	purine ribonucleoside binding
0.39	GO:0019001	guanyl nucleotide binding
0.36	GO:0032555	purine ribonucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0050254	rhodopsin kinase activity

0.38	GO:0005622	intracellular
0.36	GO:0005887	integral component of plasma membrane

0.33

EC:2.7.11.14

GO:0050254

sp|O55042|SYUA_MOUSE
Alpha-synuclein
Search

SNCA

0.97	Alpha-synuclein

0.82	GO:0014059	regulation of dopamine secretion
0.60	GO:0042417	dopamine metabolic process
0.59	GO:0051945	negative regulation of catecholamine uptake involved in synaptic transmission
0.59	GO:0051621	regulation of norepinephrine uptake
0.59	GO:1903284	positive regulation of glutathione peroxidase activity
0.59	GO:1903285	positive regulation of hydrogen peroxide catabolic process
0.59	GO:1904715	negative regulation of chaperone-mediated autophagy
0.59	GO:0032227	negative regulation of synaptic transmission, dopaminergic
0.58	GO:0043524	negative regulation of neuron apoptotic process
0.58	GO:0051612	negative regulation of serotonin uptake

0.62	GO:1903136	cuprous ion binding
0.57	GO:0048156	tau protein binding
0.57	GO:0050544	arachidonic acid binding
0.56	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.55	GO:0043014	alpha-tubulin binding
0.55	GO:0030544	Hsp70 protein binding
0.54	GO:0019894	kinesin binding
0.54	GO:0070840	dynein complex binding
0.54	GO:0051219	phosphoprotein binding
0.52	GO:0042393	histone binding

0.59	GO:0016234	inclusion body
0.57	GO:0031092	platelet alpha granule membrane
0.56	GO:0045202	synapse
0.54	GO:0030426	growth cone
0.53	GO:0043025	neuronal cell body
0.52	GO:0030424	axon
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005615	extracellular space
0.50	GO:0005938	cell cortex
0.49	GO:0005829	cytosol

0.41

GO:0016491

sp|O55047|TLK2_MOUSE
Serine/threonine-protein kinase tousled-like 2
Search

TLK2

0.90	Serine/threonine-protein kinase tousled 2

0.63	GO:0006468	protein phosphorylation
0.46	GO:0071480	cellular response to gamma radiation
0.46	GO:0001672	regulation of chromatin assembly or disassembly
0.46	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.45	GO:0018209	peptidyl-serine modification
0.42	GO:0007059	chromosome segregation
0.40	GO:0006974	cellular response to DNA damage stimulus
0.39	GO:0035556	intracellular signal transduction
0.36	GO:0016569	covalent chromatin modification
0.36	GO:0007283	spermatogenesis

0.69	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.44	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005882	intermediate filament

0.69

GO:0004674

sp|O55055|TRDMT_MOUSE
tRNA (cytosine(38)-C(5))-methyltransferase
Search

TRDMT1

0.91	tRNA aspartic acid methyltransferase 1

0.63	GO:0032259	methylation
0.48	GO:0006400	tRNA modification
0.43	GO:0001975	response to amphetamine
0.39	GO:0044260	cellular macromolecule metabolic process
0.33	GO:0006546	glycine catabolic process
0.32	GO:0055114	oxidation-reduction process

0.63	GO:0008168	methyltransferase activity
0.47	GO:0140101	catalytic activity, acting on a tRNA
0.36	GO:0003723	RNA binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0016642	oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor

0.39	GO:0005737	cytoplasm
0.36	GO:0005634	nucleus
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.63

GO:0008168

sp|O55057|PDE6D_MOUSE
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
Search

PDE6D

0.92	Phosphodiesterase 6D

0.78	GO:0007601	visual perception
0.76	GO:0034260	negative regulation of GTPase activity
0.43	GO:0001822	kidney development
0.43	GO:0001654	eye development

0.80	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.79	GO:0005095	GTPase inhibitor activity
0.72	GO:0017137	Rab GTPase binding

0.65	GO:0031410	cytoplasmic vesicle
0.62	GO:0005829	cytosol

0.80

GO:0004114

sp|O55060|TPMT_MOUSE
Thiopurine S-methyltransferase
Search

TPMT

0.68	Thiopurine S-methyltransferase

0.63	GO:0032259	methylation
0.36	GO:0033574	response to testosterone
0.32	GO:0046483	heterocycle metabolic process
0.32	GO:1901360	organic cyclic compound metabolic process
0.32	GO:0006725	cellular aromatic compound metabolic process
0.32	GO:0006807	nitrogen compound metabolic process
0.30	GO:0044238	primary metabolic process

0.84	GO:0008119	thiopurine S-methyltransferase activity
0.32	GO:0016874	ligase activity

0.37	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome

0.84

EC:2.1.1.67

GO:0008119

sp|O55070|DNSL3_MOUSE
Deoxyribonuclease gamma
Search

DNASE1L3

0.63	Deoxyribonuclease gamma

0.76	GO:0006308	DNA catabolic process
0.62	GO:0070948	regulation of neutrophil mediated cytotoxicity
0.60	GO:0002283	neutrophil activation involved in immune response
0.59	GO:0002673	regulation of acute inflammatory response
0.57	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.57	GO:0030262	apoptotic nuclear changes
0.55	GO:0010623	programmed cell death involved in cell development
0.39	GO:0002088	lens development in camera-type eye
0.39	GO:0060041	retina development in camera-type eye

0.71	GO:0004536	deoxyribonuclease activity
0.58	GO:0004519	endonuclease activity
0.36	GO:0003779	actin binding
0.35	GO:0003677	DNA binding
0.34	GO:0005509	calcium ion binding

0.47	GO:0005783	endoplasmic reticulum
0.46	GO:0005634	nucleus
0.38	GO:0005576	extracellular region
0.35	GO:0031967	organelle envelope
0.34	GO:0031982	vesicle
0.30	GO:0016020	membrane

sp|O55071|CP2BJ_MOUSE
Cytochrome P450 2B19
Search

CYP2B

0.97	Testosterone 16a-hydroxylase type b

0.53	GO:0055114	oxidation-reduction process
0.52	GO:0019373	epoxygenase P450 pathway
0.47	GO:0042738	exogenous drug catabolic process
0.44	GO:0006805	xenobiotic metabolic process
0.43	GO:0008202	steroid metabolic process
0.41	GO:0042180	cellular ketone metabolic process
0.38	GO:0014070	response to organic cyclic compound
0.36	GO:0051592	response to calcium ion
0.36	GO:0010477	response to sulfur dioxide
0.36	GO:0018933	nicotine metabolic process

0.79	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.52	GO:0008392	arachidonic acid epoxygenase activity
0.50	GO:0008395	steroid hydroxylase activity
0.37	GO:0019825	oxygen binding
0.34	GO:0004721	phosphoprotein phosphatase activity

0.42	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0031090	organelle membrane
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:1.14.14

GO:0016712

sp|O55082|PTN20_MOUSE
Tyrosine-protein phosphatase non-receptor type 20
Search

PTPN20

0.57	Tyrosine-protein phosphatase

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.43	GO:0060116	vestibular receptor cell morphogenesis
0.42	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
0.41	GO:0050885	neuromuscular process controlling balance
0.41	GO:0002244	hematopoietic progenitor cell differentiation
0.38	GO:0070830	bicellular tight junction assembly
0.35	GO:0045598	regulation of fat cell differentiation
0.35	GO:0071345	cellular response to cytokine stimulus
0.33	GO:0051603	proteolysis involved in cellular protein catabolic process
0.33	GO:0046373	L-arabinose metabolic process

0.75	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0050254	rhodopsin kinase activity
0.33	GO:0003682	chromatin binding
0.33	GO:0046556	alpha-L-arabinofuranosidase activity
0.33	GO:0070003	threonine-type peptidase activity
0.32	GO:0004175	endopeptidase activity
0.32	GO:0003677	DNA binding
0.32	GO:0046983	protein dimerization activity

0.48	GO:0005856	cytoskeleton
0.41	GO:0032421	stereocilium bundle
0.39	GO:0044446	intracellular organelle part
0.38	GO:0099512	supramolecular fiber
0.36	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0005737	cytoplasm
0.33	GO:0005694	chromosome
0.33	GO:0005839	proteasome core complex
0.32	GO:0005886	plasma membrane

0.75

EC:3.1.3.48

GO:0004725

sp|O55087|MEF2B_MOUSE
Myocyte-specific enhancer factor 2B
Search

MEF2B

0.85	LOW QUALITY PROTEIN: myocyte-specific enhancer factor 2B

0.74	GO:0045944	positive regulation of transcription by RNA polymerase II
0.57	GO:0006351	transcription, DNA-templated
0.48	GO:0007512	adult heart development
0.47	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.47	GO:0001958	endochondral ossification
0.46	GO:0035914	skeletal muscle cell differentiation
0.46	GO:0002062	chondrocyte differentiation
0.46	GO:0001649	osteoblast differentiation
0.34	GO:0006915	apoptotic process
0.33	GO:0007399	nervous system development

0.77	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.68	GO:0046983	protein dimerization activity
0.57	GO:0042826	histone deacetylase binding
0.55	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0000987	proximal promoter sequence-specific DNA binding
0.46	GO:0033613	activating transcription factor binding
0.43	GO:0042802	identical protein binding
0.41	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.41	GO:0001158	enhancer sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.48	GO:0005667	transcription factor complex
0.41	GO:0043233	organelle lumen
0.38	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm

sp|O55091|IMPCT_MOUSE
Protein IMPACT
Search

IMPACT

0.93	Impact homolog

0.86	GO:0071494	cellular response to UV-C
0.86	GO:1901561	response to benomyl
0.86	GO:1990253	cellular response to leucine starvation
0.86	GO:0071264	positive regulation of translational initiation in response to starvation
0.86	GO:0031953	negative regulation of protein autophosphorylation
0.85	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress
0.85	GO:0060733	regulation of eIF2 alpha phosphorylation by amino acid starvation
0.85	GO:0071468	cellular response to acidic pH
0.83	GO:0070301	cellular response to hydrogen peroxide
0.83	GO:1990138	neuron projection extension

0.70	GO:0043022	ribosome binding
0.70	GO:0003779	actin binding
0.44	GO:0004969	histamine receptor activity
0.34	GO:0016874	ligase activity
0.33	GO:0003676	nucleic acid binding

0.80	GO:0005844	polysome
0.40	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.34

GO:0016874

sp|O55098|STK10_MOUSE
Serine/threonine-protein kinase 10
Search

STK10

0.94	Serine/threonine-protein kinase 10-A

0.63	GO:0006468	protein phosphorylation
0.61	GO:2000401	regulation of lymphocyte migration
0.61	GO:0071593	lymphocyte aggregation
0.49	GO:0031098	stress-activated protein kinase signaling cascade
0.48	GO:0032147	activation of protein kinase activity
0.47	GO:0007346	regulation of mitotic cell cycle
0.46	GO:0042981	regulation of apoptotic process
0.40	GO:0007049	cell cycle
0.36	GO:0043312	neutrophil degranulation
0.35	GO:0001556	oocyte maturation

0.70	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0042803	protein homodimerization activity
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0045296	cadherin binding
0.32	GO:0035091	phosphatidylinositol binding

0.44	GO:0005886	plasma membrane
0.38	GO:0070062	extracellular exosome
0.37	GO:0005737	cytoplasm
0.35	GO:0012506	vesicle membrane
0.35	GO:0097708	intracellular vesicle
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0031252	cell leading edge
0.34	GO:0012505	endomembrane system
0.33	GO:0044446	intracellular organelle part

0.70

GO:0004674

sp|O55100|SNG1_MOUSE
Synaptogyrin-1
Search

SYNGR1

0.87	Putative synaptic vesicle protein synaptogyrin involved in regulation of ca2+-dependent exocytosis

0.52	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.51	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.50	GO:1990830	cellular response to leukemia inhibitory factor
0.42	GO:0048499	synaptic vesicle membrane organization
0.42	GO:0045055	regulated exocytosis
0.40	GO:0060976	coronary vasculature development
0.39	GO:0035904	aorta development
0.39	GO:0000185	activation of MAPKKK activity
0.39	GO:0006470	protein dephosphorylation
0.39	GO:0003279	cardiac septum development

0.40	GO:0004722	protein serine/threonine phosphatase activity
0.39	GO:0019209	kinase activator activity
0.37	GO:0042169	SH2 domain binding
0.37	GO:0047485	protein N-terminus binding
0.35	GO:0016301	kinase activity
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0003723	RNA binding

0.49	GO:0030672	synaptic vesicle membrane
0.49	GO:0031594	neuromuscular junction
0.40	GO:0042470	melanosome
0.39	GO:0043195	terminal bouton
0.38	GO:0030054	cell junction
0.37	GO:0016607	nuclear speck
0.36	GO:0035577	azurophil granule membrane
0.36	GO:0005829	cytosol
0.33	GO:0005840	ribosome
0.33	GO:0005886	plasma membrane

sp|O55101|SNG2_MOUSE
Synaptogyrin-2
Search

SYNGR2

0.87	Synaptogyrin

0.46	GO:0045055	regulated exocytosis
0.43	GO:0032411	positive regulation of transporter activity
0.42	GO:0048499	synaptic vesicle membrane organization
0.39	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.39	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.39	GO:0071310	cellular response to organic substance
0.39	GO:1990823	response to leukemia inhibitory factor
0.37	GO:0060976	coronary vasculature development
0.37	GO:0035904	aorta development
0.37	GO:0000185	activation of MAPKKK activity

0.44	GO:0042169	SH2 domain binding
0.43	GO:0047485	protein N-terminus binding
0.37	GO:0004722	protein serine/threonine phosphatase activity
0.37	GO:0019209	kinase activator activity
0.34	GO:0016972	thiol oxidase activity
0.32	GO:0016301	kinase activity

0.59	GO:0008021	synaptic vesicle
0.52	GO:0031594	neuromuscular junction
0.50	GO:0099501	exocytic vesicle membrane
0.40	GO:0030054	cell junction
0.37	GO:0070062	extracellular exosome
0.36	GO:0016607	nuclear speck
0.35	GO:0005829	cytosol
0.35	GO:0005811	lipid droplet
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:1.8.3.2

GO:0016972

sp|O55102|BL1S1_MOUSE
Biogenesis of lysosome-related organelles complex 1 subunit 1
Search

BLOC1S1

0.95	Biogenesis of lysosomal organelles complex 1 subunit 1

0.50	GO:0048490	anterograde synaptic vesicle transport
0.46	GO:0016197	endosomal transport
0.41	GO:0032418	lysosome localization
0.40	GO:0048753	pigment granule organization
0.40	GO:0031175	neuron projection development
0.40	GO:0018394	peptidyl-lysine acetylation
0.39	GO:0008355	olfactory learning
0.39	GO:0007274	neuromuscular synaptic transmission
0.39	GO:0036465	synaptic vesicle recycling
0.38	GO:0050808	synapse organization

0.34	GO:0005515	protein binding
0.34	GO:0008478	pyridoxal kinase activity

0.84	GO:0031083	BLOC-1 complex
0.49	GO:1904115	axon cytoplasm
0.47	GO:0005758	mitochondrial intermembrane space
0.46	GO:0005769	early endosome
0.45	GO:0005759	mitochondrial matrix
0.42	GO:0099078	BORC complex
0.40	GO:0005765	lysosomal membrane
0.37	GO:0045202	synapse
0.36	GO:0070062	extracellular exosome
0.34	GO:0005788	endoplasmic reticulum lumen

0.34

EC:2.7.1.35

GO:0008478

sp|O55103|PRAX_MOUSE
Periaxin
Search

PRX

0.91

Periaxin

0.55	GO:0032290	peripheral nervous system myelin formation
0.52	GO:0032287	peripheral nervous system myelin maintenance
0.51	GO:0019233	sensory perception of pain
0.51	GO:0019226	transmission of nerve impulse
0.49	GO:0043484	regulation of RNA splicing
0.44	GO:0021675	nerve development
0.35	GO:1901385	regulation of voltage-gated calcium channel activity
0.33	GO:0055114	oxidation-reduction process

0.41	GO:0005515	protein binding
0.33	GO:0016491	oxidoreductase activity
0.32	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
0.32	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.50	GO:0030054	cell junction
0.49	GO:0005737	cytoplasm
0.43	GO:0043209	myelin sheath
0.42	GO:0005886	plasma membrane
0.34	GO:0070062	extracellular exosome
0.34	GO:0045121	membrane raft
0.34	GO:0015629	actin cytoskeleton
0.30	GO:0016021	integral component of membrane

0.33

GO:0016491

sp|O55106|STRN_MOUSE
Striatin
Search

STRN

0.96

Striatin

0.76	GO:0008285	negative regulation of cell proliferation
0.74	GO:0016055	Wnt signaling pathway
0.44	GO:0016358	dendrite development
0.43	GO:0007626	locomotory behavior
0.40	GO:0070830	bicellular tight junction assembly
0.34	GO:0000187	activation of MAPK activity
0.34	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.34	GO:0048666	neuron development
0.34	GO:0018108	peptidyl-tyrosine phosphorylation

0.85	GO:0070016	armadillo repeat domain binding
0.84	GO:0030331	estrogen receptor binding
0.84	GO:0051721	protein phosphatase 2A binding
0.72	GO:0032403	protein complex binding
0.45	GO:0005516	calmodulin binding
0.40	GO:0048306	calcium-dependent protein binding
0.35	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.34	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.78	GO:0005923	bicellular tight junction
0.77	GO:0000159	protein phosphatase type 2A complex
0.47	GO:0043197	dendritic spine
0.43	GO:0014069	postsynaptic density
0.43	GO:0043025	neuronal cell body
0.42	GO:0045211	postsynaptic membrane
0.36	GO:0005737	cytoplasm
0.35	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.35

EC:2.3.1

GO:0016747

sp|O55111|DSG2_MOUSE
Desmoglein-2
Search

DSG2

0.96	Putative cadherin egf lag seven-pass g-type receptor

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.67	GO:0003165	Purkinje myocyte development
0.66	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication
0.65	GO:0098911	regulation of ventricular cardiac muscle cell action potential
0.64	GO:0002934	desmosome organization
0.63	GO:0086091	regulation of heart rate by cardiac conduction
0.43	GO:0032570	response to progesterone
0.43	GO:0060135	maternal process involved in female pregnancy
0.37	GO:0050821	protein stabilization
0.37	GO:0070268	cornification

0.70	GO:0005509	calcium ion binding
0.59	GO:0050839	cell adhesion molecule binding
0.40	GO:0045295	gamma-catenin binding
0.38	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
0.32	GO:0015643	toxic substance binding

0.63	GO:0030057	desmosome
0.63	GO:0014704	intercalated disc
0.55	GO:0005886	plasma membrane
0.45	GO:0043227	membrane-bounded organelle
0.43	GO:0043229	intracellular organelle
0.41	GO:0045177	apical part of cell
0.39	GO:0043230	extracellular organelle
0.38	GO:0005615	extracellular space
0.38	GO:0009986	cell surface
0.37	GO:0098562	cytoplasmic side of membrane

sp|O55112|AFF2_MOUSE
AF4/FMR2 family member 2
Search

sp|O55123|MMP10_MOUSE
Stromelysin-2
Search

MMP3

0.70	Matrix metalloproteinase

0.63	GO:0030574	collagen catabolic process
0.61	GO:0006508	proteolysis
0.55	GO:0010727	negative regulation of hydrogen peroxide metabolic process
0.53	GO:0032461	positive regulation of protein oligomerization
0.52	GO:0022617	extracellular matrix disassembly
0.49	GO:0003417	growth plate cartilage development
0.49	GO:0001958	endochondral ossification
0.49	GO:0030282	bone mineralization
0.49	GO:0030334	regulation of cell migration
0.39	GO:1903209	positive regulation of oxidative stress-induced cell death

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.49	GO:0005518	collagen binding
0.44	GO:0005509	calcium ion binding
0.38	GO:0004252	serine-type endopeptidase activity
0.36	GO:0001047	core promoter binding
0.34	GO:0001968	fibronectin binding
0.34	GO:0050750	low-density lipoprotein particle receptor binding
0.34	GO:0048306	calcium-dependent protein binding
0.34	GO:0043565	sequence-specific DNA binding

0.74	GO:0031012	extracellular matrix
0.42	GO:0042406	extrinsic component of endoplasmic reticulum membrane
0.40	GO:0005615	extracellular space
0.35	GO:0005829	cytosol
0.35	GO:0005581	collagen trimer
0.35	GO:0030425	dendrite
0.35	GO:0044297	cell body
0.35	GO:0046581	intercellular canaliculus
0.34	GO:0005634	nucleus
0.34	GO:0005739	mitochondrion

0.70

GO:0004222

sp|O55125|NIPS1_MOUSE
Protein NipSnap homolog 1
Search

NIPSNAP1

0.95	LOW QUALITY PROTEIN: protein NipSnap homolog 1

0.80	GO:0019233	sensory perception of pain
0.53	GO:2000984	negative regulation of ATP citrate synthase activity
0.45	GO:0006754	ATP biosynthetic process
0.42	GO:0006119	oxidative phosphorylation

0.76	GO:0042165	neurotransmitter binding
0.39	GO:0005515	protein binding

0.72	GO:0097060	synaptic membrane
0.60	GO:0005739	mitochondrion
0.59	GO:0031967	organelle envelope
0.59	GO:0031090	organelle membrane
0.45	GO:0098805	whole membrane
0.43	GO:0019867	outer membrane

sp|O55126|NIPS2_MOUSE
Protein NipSnap homolog 2
Search

NIPSNAP2

0.96	Nipsnap homolog 2

0.85	GO:2000984	negative regulation of ATP citrate synthase activity
0.66	GO:0006754	ATP biosynthetic process
0.60	GO:0006119	oxidative phosphorylation
0.51	GO:1901843	positive regulation of high voltage-gated calcium channel activity
0.39	GO:0019233	sensory perception of pain

0.38	GO:0042165	neurotransmitter binding
0.36	GO:0005515	protein binding

0.72	GO:0005741	mitochondrial outer membrane
0.38	GO:0044459	plasma membrane part
0.37	GO:0044456	synapse part
0.35	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

sp|O55127|CP26A_MOUSE
Cytochrome P450 26A1
Search

CYP26A1

0.97	Cytochrome P450 family 26 subfamily A polypeptide 1

0.80	GO:0034653	retinoic acid catabolic process
0.65	GO:0006805	xenobiotic metabolic process
0.53	GO:0016125	sterol metabolic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0014032	neural crest cell development
0.51	GO:0009952	anterior/posterior pattern specification
0.49	GO:0007417	central nervous system development
0.49	GO:0048284	organelle fusion
0.39	GO:0071300	cellular response to retinoic acid
0.39	GO:0048384	retinoic acid receptor signaling pathway

0.83	GO:0008401	retinoic acid 4-hydroxylase activity
0.79	GO:0001972	retinoic acid binding
0.63	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding

0.30

GO:0016020

membrane

0.63

EC:1.14.13

GO:0016709

sp|O55128|SAP18_MOUSE
Histone deacetylase complex subunit SAP18
Search

SAP18

0.90	Histone deacetylase complex subunit SAP18

0.54	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.52	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.50	GO:0043065	positive regulation of apoptotic process
0.45	GO:0008380	RNA splicing
0.43	GO:0006397	mRNA processing
0.40	GO:0006325	chromatin organization
0.40	GO:1903507	negative regulation of nucleic acid-templated transcription
0.39	GO:0006351	transcription, DNA-templated
0.39	GO:0006355	regulation of transcription, DNA-templated
0.39	GO:0045814	negative regulation of gene expression, epigenetic

0.40	GO:0005515	protein binding
0.39	GO:0003714	transcription corepressor activity
0.39	GO:0004407	histone deacetylase activity
0.39	GO:0003723	RNA binding
0.38	GO:0004565	beta-galactosidase activity
0.38	GO:0004452	isopentenyl-diphosphate delta-isomerase activity

0.77	GO:0016604	nuclear body
0.66	GO:0005829	cytosol
0.58	GO:0061574	ASAP complex
0.51	GO:0035145	exon-exon junction complex
0.42	GO:0000118	histone deacetylase complex
0.38	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

0.39	EC:3.5.1.98	GO:0004407
0.38	KEGG:R01123	GO:0004452

sp|O55131|SEPT7_MOUSE
Septin-7
Search

SEPT7

0.92	Septin-7 isoform A

0.42	GO:0016476	regulation of embryonic cell shape
0.40	GO:0060271	cilium assembly
0.39	GO:0007283	spermatogenesis
0.38	GO:1902857	positive regulation of non-motile cilium assembly
0.38	GO:0051301	cell division
0.38	GO:0030154	cell differentiation
0.38	GO:0051291	protein heterooligomerization
0.38	GO:0031270	pseudopodium retraction
0.38	GO:0007049	cell cycle
0.37	GO:0097061	dendritic spine organization

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0045296	cadherin binding
0.36	GO:0042802	identical protein binding
0.35	GO:0046982	protein heterodimerization activity
0.33	GO:0005198	structural molecule activity

0.85	GO:0031105	septin complex
0.41	GO:0032154	cleavage furrow
0.41	GO:0030496	midbody
0.40	GO:0005930	axoneme
0.40	GO:0016324	apical plasma membrane
0.40	GO:0000777	condensed chromosome kinetochore
0.39	GO:0005819	spindle
0.38	GO:0097227	sperm annulus
0.38	GO:0097517	contractile actin filament bundle
0.37	GO:0042641	actomyosin

sp|O55134|PCD12_MOUSE
Protocadherin-12
Search

PCDH12

0.97	Protocadherin-12

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.64	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.63	GO:0060711	labyrinthine layer development
0.56	GO:0005977	glycogen metabolic process
0.52	GO:0007399	nervous system development
0.49	GO:0007267	cell-cell signaling
0.43	GO:1990709	presynaptic active zone organization
0.43	GO:2000807	regulation of synaptic vesicle clustering
0.42	GO:0099172	presynapse organization
0.42	GO:0050805	negative regulation of synaptic transmission

0.70	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding

0.69	GO:0005911	cell-cell junction
0.55	GO:0005886	plasma membrane
0.39	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|O55135|IF6_MOUSE
Eukaryotic translation initiation factor 6
Search

EIF6

0.68	Eukaryotic translation initiation factor 6

0.78	GO:0042256	mature ribosome assembly
0.72	GO:0042273	ribosomal large subunit biogenesis
0.71	GO:0006413	translational initiation
0.62	GO:0000054	ribosomal subunit export from nucleus
0.56	GO:0045652	regulation of megakaryocyte differentiation
0.55	GO:0006110	regulation of glycolytic process
0.54	GO:0042304	regulation of fatty acid biosynthetic process
0.54	GO:0032868	response to insulin
0.53	GO:2000377	regulation of reactive oxygen species metabolic process
0.51	GO:0045727	positive regulation of translation

0.74	GO:0043022	ribosome binding
0.74	GO:0043023	ribosomal large subunit binding
0.72	GO:0003743	translation initiation factor activity
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.69	GO:0005730	nucleolus
0.57	GO:0005638	lamin filament
0.47	GO:0005737	cytoplasm
0.46	GO:0030687	preribosome, large subunit precursor
0.38	GO:0005654	nucleoplasm
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.32

GO:0016787

sp|O55137|ACOT1_MOUSE
Acyl-coenzyme A thioesterase 1
Search

0.55	Acyl-coenzyme A thioesterase 2, mitochondrial

0.73	GO:0035383	thioester metabolic process
0.64	GO:0032789	unsaturated monocarboxylic acid metabolic process
0.64	GO:0032788	saturated monocarboxylic acid metabolic process
0.63	GO:0006732	coenzyme metabolic process
0.61	GO:0000038	very long-chain fatty acid metabolic process
0.59	GO:0001676	long-chain fatty acid metabolic process
0.54	GO:0006793	phosphorus metabolic process
0.53	GO:0043649	dicarboxylic acid catabolic process
0.53	GO:0046459	short-chain fatty acid metabolic process
0.38	GO:0070849	response to epidermal growth factor

0.76	GO:0016790	thiolester hydrolase activity
0.52	GO:0005102	receptor binding
0.47	GO:0052689	carboxylic ester hydrolase activity

0.55	GO:0005777	peroxisome
0.42	GO:0005829	cytosol
0.40	GO:0005759	mitochondrial matrix
0.40	GO:0070062	extracellular exosome
0.37	GO:0031907	microbody lumen

0.76	EC:3.1.2	GO:0016790
0.47	KEGG:R00630	GO:0052689

sp|O55142|RL35A_MOUSE
60S ribosomal protein L35a
Search

RPL35A

0.67	Ribosomal protein L35

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.52	GO:0042273	ribosomal large subunit biogenesis
0.43	GO:0016072	rRNA metabolic process
0.43	GO:0030218	erythrocyte differentiation
0.41	GO:0043009	chordate embryonic development
0.36	GO:0007155	cell adhesion
0.35	GO:0006508	proteolysis

0.64	GO:0003735	structural constituent of ribosome
0.38	GO:0000049	tRNA binding
0.36	GO:0004222	metalloendopeptidase activity
0.34	GO:0035091	phosphatidylinositol binding
0.33	GO:0030234	enzyme regulator activity
0.33	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.47	GO:0044445	cytosolic part
0.41	GO:0044446	intracellular organelle part
0.37	GO:0005739	mitochondrion
0.35	GO:0031012	extracellular matrix
0.34	GO:0070062	extracellular exosome
0.33	GO:1905369	endopeptidase complex
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.36

GO:0004222

sp|O55143|AT2A2_MOUSE
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
Search

ATP2A2

0.54	Calcium-transporting ATPase

0.76	GO:0070588	calcium ion transmembrane transport
0.68	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.57	GO:0032470	positive regulation of endoplasmic reticulum calcium ion concentration
0.57	GO:1903233	regulation of calcium ion-dependent exocytosis of neurotransmitter
0.57	GO:0033292	T-tubule organization
0.56	GO:0014883	transition between fast and slow fiber
0.56	GO:0070296	sarcoplasmic reticulum calcium ion transport
0.55	GO:0003299	muscle hypertrophy in response to stress
0.55	GO:0008016	regulation of heart contraction
0.55	GO:0014887	cardiac muscle adaptation

0.79	GO:0005388	calcium-transporting ATPase activity
0.54	GO:0044548	S100 protein binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0019899	enzyme binding
0.47	GO:0005509	calcium ion binding
0.39	GO:0031775	lutropin-choriogonadotropic hormone receptor binding
0.38	GO:0008022	protein C-terminus binding

0.56	GO:0097470	ribbon synapse
0.54	GO:0016529	sarcoplasmic reticulum
0.48	GO:0005789	endoplasmic reticulum membrane
0.47	GO:0005654	nucleoplasm
0.39	GO:0090534	calcium ion-transporting ATPase complex
0.39	GO:0098588	bounding membrane of organelle
0.38	GO:0014704	intercalated disc
0.37	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.37	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0012506	vesicle membrane

0.79

EC:3.6.3.8

GO:0005388

sp|O55144|TLX3_MOUSE
T-cell leukemia homeobox protein 3
Search

TLX3

0.96	T-cell leukemia homeobox protein 3

0.57	GO:0002087	regulation of respiratory gaseous exchange by neurological system process
0.56	GO:0007585	respiratory gaseous exchange
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0048665	neuron fate specification
0.55	GO:0010468	regulation of gene expression
0.54	GO:0001764	neuron migration
0.54	GO:0045665	negative regulation of neuron differentiation
0.51	GO:0007417	central nervous system development
0.42	GO:0048839	inner ear development

0.63	GO:0043565	sequence-specific DNA binding
0.42	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.41	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0001012	RNA polymerase II regulatory region DNA binding
0.39	GO:0003690	double-stranded DNA binding
0.35	GO:0005515	protein binding
0.33	GO:0005198	structural molecule activity

0.60	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.34	GO:0045111	intermediate filament cytoskeleton
0.34	GO:0099512	supramolecular fiber

sp|O55176|PJA1_MOUSE
E3 ubiquitin-protein ligase Praja-1
Search

PJA2

0.92	Praja ring finger ubiquitin ligase 1

0.73	GO:0016567	protein ubiquitination
0.70	GO:0010738	regulation of protein kinase A signaling
0.69	GO:0035329	hippo signaling
0.52	GO:0030163	protein catabolic process

0.74	GO:0004842	ubiquitin-protein transferase activity
0.66	GO:0061659	ubiquitin-like protein ligase activity
0.60	GO:0034236	protein kinase A catalytic subunit binding
0.59	GO:0034237	protein kinase A regulatory subunit binding
0.35	GO:0016874	ligase activity

0.55	GO:0045111	intermediate filament cytoskeleton
0.45	GO:0005737	cytoplasm
0.43	GO:0005886	plasma membrane

0.35	EC:6	GO:0016874
0.74	KEGG:R03876	GO:0004842

tr|O55179|O55179_MOUSE
A1-d protein
Search

0.78	GO:0043066	negative regulation of apoptotic process
0.61	GO:0001836	release of cytochrome c from mitochondria
0.61	GO:0038034	signal transduction in absence of ligand
0.59	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.59	GO:0097191	extrinsic apoptotic signaling pathway
0.59	GO:0008053	mitochondrial fusion
0.56	GO:0043065	positive regulation of apoptotic process
0.43	GO:0055085	transmembrane transport
0.43	GO:0048513	animal organ development
0.42	GO:0050852	T cell receptor signaling pathway

0.54	GO:0046982	protein heterodimerization activity
0.54	GO:0042803	protein homodimerization activity
0.51	GO:0022803	passive transmembrane transporter activity
0.43	GO:0051400	BH domain binding
0.42	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.36	GO:0016874	ligase activity

0.55	GO:0005741	mitochondrial outer membrane
0.30	GO:0016021	integral component of membrane

0.36

GO:0016874

sp|O55183|STC1_MOUSE
Stanniocalcin-1
Search

STC1

0.97	Stanniocalcin

0.76	GO:0010469	regulation of receptor activity
0.63	GO:0003421	growth plate cartilage axis specification
0.63	GO:1903403	negative regulation of renal phosphate excretion
0.61	GO:0001886	endothelial cell morphogenesis
0.60	GO:0035988	chondrocyte proliferation
0.60	GO:0090280	positive regulation of calcium ion import
0.59	GO:0086004	regulation of cardiac muscle cell contraction
0.59	GO:0010596	negative regulation of endothelial cell migration
0.58	GO:0051926	negative regulation of calcium ion transport
0.58	GO:0044070	regulation of anion transport

0.79	GO:0005179	hormone activity
0.33	GO:0043565	sequence-specific DNA binding

0.66	GO:0005576	extracellular region
0.46	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.39	GO:0016324	apical plasma membrane
0.33	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system

sp|O55186|CD59A_MOUSE
CD59A glycoprotein
Search

sp|O55187|CBX4_MOUSE
E3 SUMO-protein ligase CBX4
Search

CBX4

0.83	E3 SUMO-protein ligase CBX4

0.43	GO:0016925	protein sumoylation
0.42	GO:0043066	negative regulation of apoptotic process
0.42	GO:0000122	negative regulation of transcription by RNA polymerase II
0.41	GO:0016569	covalent chromatin modification
0.37	GO:0006351	transcription, DNA-templated

0.60	GO:0016874	ligase activity
0.45	GO:0032183	SUMO binding
0.44	GO:0140034	methylation-dependent protein binding
0.44	GO:0051219	phosphoprotein binding
0.44	GO:0019789	SUMO transferase activity
0.43	GO:0003714	transcription corepressor activity
0.43	GO:0042393	histone binding
0.43	GO:0003727	single-stranded RNA binding
0.42	GO:0003682	chromatin binding
0.42	GO:0044212	transcription regulatory region DNA binding

0.54	GO:0005634	nucleus
0.42	GO:0000151	ubiquitin ligase complex
0.40	GO:0031974	membrane-enclosed lumen
0.38	GO:0043234	protein complex
0.37	GO:0044446	intracellular organelle part

0.60

GO:0016874

sp|O55188|DMP1_MOUSE
Dentin matrix acidic phosphoprotein 1
Search

DMP1

0.86	Dentin matrix acidic phosphoprotein 1

0.82	GO:0001503	ossification
0.80	GO:0030198	extracellular matrix organization
0.51	GO:0070173	regulation of enamel mineralization
0.48	GO:0010811	positive regulation of cell-substrate adhesion
0.39	GO:0031214	biomineral tissue development
0.35	GO:0007155	cell adhesion
0.34	GO:0043687	post-translational protein modification
0.32	GO:0030500	regulation of bone mineralization

0.48	GO:0050840	extracellular matrix binding
0.35	GO:0005178	integrin binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0030544	Hsp70 protein binding

0.37	GO:0005578	proteinaceous extracellular matrix
0.35	GO:0005634	nucleus
0.35	GO:0005788	endoplasmic reticulum lumen

sp|O55189|AMBN_MOUSE
Ameloblastin
Search

AMBN

0.91	Ameloblastin

0.85	GO:0042475	odontogenesis of dentin-containing tooth
0.49	GO:0031214	biomineral tissue development
0.44	GO:0008283	cell proliferation
0.42	GO:0010469	regulation of receptor activity
0.42	GO:0007155	cell adhesion
0.39	GO:0030198	extracellular matrix organization
0.35	GO:0043687	post-translational protein modification

0.87	GO:0030345	structural constituent of tooth enamel
0.43	GO:0008083	growth factor activity

0.45	GO:0005578	proteinaceous extracellular matrix
0.36	GO:0005788	endoplasmic reticulum lumen

sp|O55192|SC6A2_MOUSE
Sodium-dependent noradrenaline transporter
Search

SLC6A2

0.77	Sodium-dependent noradrenaline transporter

0.76	GO:0006836	neurotransmitter transport
0.55	GO:0055085	transmembrane transport
0.51	GO:0015874	norepinephrine transport
0.50	GO:0090494	dopamine uptake
0.50	GO:0001963	synaptic transmission, dopaminergic
0.47	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.46	GO:0048265	response to pain
0.44	GO:0001505	regulation of neurotransmitter levels
0.44	GO:0098657	import into cell
0.43	GO:0051649	establishment of localization in cell

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.51	GO:0005333	norepinephrine transmembrane transporter activity
0.50	GO:0005329	dopamine transmembrane transporter activity
0.46	GO:0043014	alpha-tubulin binding
0.45	GO:0048487	beta-tubulin binding
0.38	GO:0046872	metal ion binding

0.63	GO:0005887	integral component of plasma membrane
0.46	GO:0043005	neuron projection
0.44	GO:0045121	membrane raft
0.42	GO:0009986	cell surface

sp|O55196|ENAM_MOUSE
Enamelin
Search

ENAM

0.93

Enamelin

0.87	GO:0036305	ameloblast differentiation
0.86	GO:0070175	positive regulation of enamel mineralization
0.85	GO:0097186	amelogenesis
0.66	GO:0022604	regulation of cell morphogenesis
0.57	GO:0031214	biomineral tissue development

0.85

GO:0030345

structural constituent of tooth enamel

0.72	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

sp|O55201|SPT5H_MOUSE
Transcription elongation factor SPT5
Search

SUPT5H

0.66	Transcription elongation factor SPT5

0.71	GO:0032784	regulation of DNA-templated transcription, elongation
0.67	GO:0006357	regulation of transcription by RNA polymerase II
0.56	GO:1900364	negative regulation of mRNA polyadenylation
0.56	GO:0006414	translational elongation
0.54	GO:0006351	transcription, DNA-templated
0.54	GO:0016239	positive regulation of macroautophagy
0.49	GO:0045893	positive regulation of transcription, DNA-templated
0.48	GO:0045892	negative regulation of transcription, DNA-templated
0.43	GO:0006397	mRNA processing
0.35	GO:0050434	positive regulation of viral transcription

0.56	GO:0003746	translation elongation factor activity
0.49	GO:0046982	protein heterodimerization activity
0.49	GO:0003682	chromatin binding
0.48	GO:0019899	enzyme binding
0.45	GO:0003729	mRNA binding
0.38	GO:0003677	DNA binding

0.58

GO:0032044

DSIF complex

sp|O55203|LDB2_MOUSE
LIM domain-binding protein 2
Search

LDB2

0.94	LIM domain-binding protein 2

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.54	GO:0010669	epithelial structure maintenance
0.54	GO:0035019	somatic stem cell population maintenance
0.51	GO:0001942	hair follicle development
0.50	GO:0030334	regulation of cell migration
0.50	GO:0044089	positive regulation of cellular component biogenesis
0.49	GO:0043549	regulation of kinase activity
0.48	GO:0045893	positive regulation of transcription, DNA-templated
0.41	GO:1900108	negative regulation of nodal signaling pathway
0.39	GO:0090288	negative regulation of cellular response to growth factor stimulus

0.86	GO:0030274	LIM domain binding
0.75	GO:0000989	transcription factor activity, transcription factor binding
0.47	GO:0019899	enzyme binding
0.38	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.51	GO:0031252	cell leading edge
0.49	GO:0005667	transcription factor complex
0.46	GO:0031974	membrane-enclosed lumen
0.43	GO:0043232	intracellular non-membrane-bounded organelle
0.42	GO:0044446	intracellular organelle part
0.41	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|O55208|FIGLA_MOUSE
Factor in the germline alpha
Search

FIGLA

0.96	Folliculogenesis-specific bHLH transcription factor

0.51	GO:0006366	transcription by RNA polymerase II
0.51	GO:0045944	positive regulation of transcription by RNA polymerase II

0.72	GO:0008134	transcription factor binding
0.68	GO:0046983	protein dimerization activity
0.64	GO:0043565	sequence-specific DNA binding
0.54	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003690	double-stranded DNA binding

0.74

GO:0005667

transcription factor complex

sp|O55222|ILK_MOUSE
Integrin-linked protein kinase
Search

ILK

0.96	Integrin-linked protein kinase

0.73	GO:0007229	integrin-mediated signaling pathway
0.62	GO:0006468	protein phosphorylation
0.60	GO:0034446	substrate adhesion-dependent cell spreading
0.60	GO:0010761	fibroblast migration
0.59	GO:2000178	negative regulation of neural precursor cell proliferation
0.58	GO:0043491	protein kinase B signaling
0.58	GO:0032292	peripheral nervous system axon ensheathment
0.58	GO:0001658	branching involved in ureteric bud morphogenesis
0.58	GO:0014044	Schwann cell development
0.58	GO:1901224	positive regulation of NIK/NF-kappaB signaling

0.62	GO:0004672	protein kinase activity
0.54	GO:0019901	protein kinase binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0004871	signal transducer activity
0.39	GO:0005178	integrin binding
0.38	GO:0017124	SH3 domain binding

0.58	GO:0005925	focal adhesion
0.57	GO:0030027	lamellipodium
0.50	GO:0005654	nucleoplasm
0.49	GO:0097517	contractile actin filament bundle
0.49	GO:0042641	actomyosin
0.49	GO:0005829	cytosol
0.45	GO:0030017	sarcomere
0.40	GO:0042383	sarcolemma
0.40	GO:0043034	costamere
0.39	GO:0043198	dendritic shaft

sp|O55225|OTOG_MOUSE
Otogelin
Search

OTOG

0.92

Otogelin

0.84	GO:0008344	adult locomotory behavior
0.82	GO:0007605	sensory perception of sound
0.77	GO:0046373	L-arabinose metabolic process
0.43	GO:0032474	otolith morphogenesis
0.42	GO:0035889	otolith tethering
0.38	GO:0048646	anatomical structure formation involved in morphogenesis
0.36	GO:0048752	semicircular canal morphogenesis

0.79	GO:0046556	alpha-L-arabinofuranosidase activity
0.61	GO:0005198	structural molecule activity

0.61	GO:0005576	extracellular region
0.41	GO:0016324	apical plasma membrane
0.39	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:3.2.1.55

GO:0046556

sp|O55226|CHAD_MOUSE
Chondroadherin
Search

CHAD

0.97	Chondroadherin

0.84	GO:1900155	negative regulation of bone trabecula formation
0.75	GO:0060348	bone development
0.64	GO:0046426	negative regulation of JAK-STAT cascade
0.60	GO:0006469	negative regulation of protein kinase activity
0.60	GO:0019221	cytokine-mediated signaling pathway
0.57	GO:1904027	negative regulation of collagen fibril organization
0.55	GO:0032331	negative regulation of chondrocyte differentiation
0.40	GO:0001502	cartilage condensation
0.34	GO:0007409	axonogenesis
0.33	GO:0006468	protein phosphorylation

0.62	GO:0004860	protein kinase inhibitor activity
0.57	GO:0098633	collagen fibril binding
0.52	GO:0005518	collagen binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0030246	carbohydrate binding

0.54	GO:0031012	extracellular matrix
0.41	GO:0005737	cytoplasm
0.32	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.33

GO:0004674

sp|O55229|CHKB_MOUSE
Choline/ethanolamine kinase
Search

0.64	Choline kinase alpha

0.62	GO:0006657	CDP-choline pathway
0.57	GO:0016310	phosphorylation
0.54	GO:0006646	phosphatidylethanolamine biosynthetic process
0.47	GO:0007517	muscle organ development
0.38	GO:1904681	response to 3-methylcholanthrene
0.36	GO:0006580	ethanolamine metabolic process
0.36	GO:0019695	choline metabolic process
0.35	GO:0009636	response to toxic substance
0.33	GO:0006869	lipid transport
0.32	GO:0007165	signal transduction

0.64	GO:0004103	choline kinase activity
0.59	GO:0004305	ethanolamine kinase activity
0.52	GO:0004104	cholinesterase activity
0.48	GO:0042803	protein homodimerization activity
0.41	GO:0008144	drug binding
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0033265	choline binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004871	signal transducer activity

0.36

GO:0005829

cytosol

0.64	EC:2.7.1.32	GO:0004103
0.64	KEGG:R01021	GO:0004103

sp|O55230|RA51D_MOUSE
DNA repair protein RAD51 homolog 4
Search

RAD51D

0.95	Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase

0.64	GO:0006281	DNA repair
0.61	GO:0042148	strand invasion
0.54	GO:0000723	telomere maintenance
0.51	GO:0051726	regulation of cell cycle
0.49	GO:0090735	DNA repair complex assembly
0.48	GO:0006312	mitotic recombination
0.48	GO:0010212	response to ionizing radiation
0.47	GO:0007131	reciprocal meiotic recombination
0.46	GO:0065004	protein-DNA complex assembly
0.40	GO:1900426	positive regulation of defense response to bacterium

0.69	GO:0008094	DNA-dependent ATPase activity
0.60	GO:0000400	four-way junction DNA binding
0.56	GO:0043015	gamma-tubulin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0003697	single-stranded DNA binding
0.45	GO:0000150	recombinase activity
0.44	GO:0004520	endodeoxyribonuclease activity
0.44	GO:0003690	double-stranded DNA binding

0.59	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex
0.55	GO:0000784	nuclear chromosome, telomeric region
0.54	GO:0005813	centrosome
0.53	GO:0005657	replication fork
0.39	GO:0005737	cytoplasm
0.34	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

sp|O55233|CER1_MOUSE
Cerberus
Search

CER1

0.97	Cerberus 1 homolog (Xenopus laevis)

0.76	GO:0035582	sequestering of BMP in extracellular matrix
0.75	GO:2000381	negative regulation of mesoderm development
0.75	GO:0003419	growth plate cartilage chondrocyte proliferation
0.75	GO:0032926	negative regulation of activin receptor signaling pathway
0.74	GO:0048263	determination of dorsal identity
0.72	GO:0023019	signal transduction involved in regulation of gene expression
0.72	GO:0030282	bone mineralization
0.70	GO:0042074	cell migration involved in gastrulation
0.69	GO:0001657	ureteric bud development
0.69	GO:0009948	anterior/posterior axis specification

0.75	GO:0016015	morphogen activity
0.73	GO:0036122	BMP binding
0.61	GO:0042803	protein homodimerization activity
0.42	GO:0005125	cytokine activity
0.36	GO:0017147	Wnt-protein binding
0.35	GO:0038100	nodal binding

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|O55234|PSB5_MOUSE
Proteasome subunit beta type-5
Search

PSMB5

0.53	Proteasome subunit beta type

0.73	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.48	GO:0006979	response to oxidative stress
0.40	GO:0080129	proteasome core complex assembly
0.39	GO:0010499	proteasomal ubiquitin-independent protein catabolic process
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.36	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.36	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation

0.76	GO:0070003	threonine-type peptidase activity
0.64	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding

0.74	GO:0005839	proteasome core complex
0.60	GO:0005634	nucleus
0.51	GO:0005813	centrosome
0.48	GO:0005737	cytoplasm
0.46	GO:0031974	membrane-enclosed lumen
0.36	GO:0070062	extracellular exosome

sp|O55236|MCE1_MOUSE
mRNA-capping enzyme
Search

RNGTT

0.86	mRNA-capping enzyme

0.83	GO:0098507	polynucleotide 5' dephosphorylation
0.75	GO:0006370	7-methylguanosine mRNA capping
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.34	GO:0006366	transcription by RNA polymerase II
0.33	GO:0016032	viral process
0.33	GO:0007018	microtubule-based movement

0.84	GO:0004484	mRNA guanylyltransferase activity
0.83	GO:0004651	polynucleotide 5'-phosphatase activity
0.78	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.60	GO:0032550	purine ribonucleoside binding
0.60	GO:0019001	guanyl nucleotide binding
0.59	GO:0050355	triphosphatase activity
0.50	GO:0032555	purine ribonucleotide binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0016459	myosin complex
0.30	GO:0031224	intrinsic component of membrane

0.84	EC:2.7.7.50	GO:0004484
0.59	KEGG:R00138	GO:0050355

sp|O55237|CD70_MOUSE
CD70 antigen
Search

sp|O55239|NNMT_MOUSE
Nicotinamide N-methyltransferase
Search

NNMT

0.89	Indolethylamine N-methyltransferase

0.63	GO:0032259	methylation
0.42	GO:0031100	animal organ regeneration
0.40	GO:0010243	response to organonitrogen compound
0.38	GO:0042493	response to drug
0.38	GO:0042418	epinephrine biosynthetic process
0.37	GO:0009308	amine metabolic process
0.36	GO:0009636	response to toxic substance
0.36	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway
0.34	GO:0035900	response to isolation stress
0.34	GO:0035902	response to immobilization stress

0.63	GO:0008168	methyltransferase activity
0.33	GO:0005515	protein binding

0.49	GO:0005829	cytosol
0.34	GO:0043196	varicosity
0.34	GO:0043204	perikaryon
0.34	GO:0043195	terminal bouton
0.33	GO:0030425	dendrite
0.32	GO:0005634	nucleus

0.63

GO:0008168

sp|O55240|RDH1_MOUSE
11-cis retinol dehydrogenase
Search

RDH5

0.89	Microsomal NAD+-dependent retinol dehydrogenase 4

0.51	GO:0001523	retinoid metabolic process
0.48	GO:0055114	oxidation-reduction process
0.44	GO:0034754	cellular hormone metabolic process
0.44	GO:0034308	primary alcohol metabolic process
0.42	GO:0016102	diterpenoid biosynthetic process
0.42	GO:0035138	pectoral fin morphogenesis
0.42	GO:0031017	exocrine pancreas development
0.41	GO:0030154	cell differentiation
0.41	GO:0035050	embryonic heart tube development
0.41	GO:0042362	fat-soluble vitamin biosynthetic process

0.52	GO:0004745	retinol dehydrogenase activity
0.39	GO:0016229	steroid dehydrogenase activity
0.35	GO:0042803	protein homodimerization activity

0.59	GO:0005788	endoplasmic reticulum lumen
0.40	GO:0044297	cell body
0.38	GO:0005829	cytosol
0.36	GO:0005730	nucleolus
0.35	GO:0031301	integral component of organelle membrane
0.34	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0043234	protein complex

0.52

EC:1.1.1.105

GO:0004745

sp|O55241|OREX_MOUSE
Orexin
Search

HCRT

0.87	Hypocretin neuropeptide precursor

0.84	GO:0007631	feeding behavior
0.80	GO:0007218	neuropeptide signaling pathway
0.60	GO:0042746	circadian sleep/wake cycle, wakefulness
0.56	GO:0030431	sleep
0.55	GO:0033555	multicellular organismal response to stress
0.51	GO:0042594	response to starvation
0.36	GO:0035556	intracellular signal transduction
0.30	GO:0001659	temperature homeostasis
0.30	GO:0031645	negative regulation of neurological system process
0.30	GO:0031646	positive regulation of neurological system process

0.30	GO:0005515	protein binding
0.30	GO:0098772	molecular function regulator

0.50	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0043227	membrane-bounded organelle
0.30	GO:0044456	synapse part
0.30	GO:0043229	intracellular organelle
0.30	GO:0012505	endomembrane system
0.30	GO:0030054	cell junction

sp|O55242|SGMR1_MOUSE
Sigma non-opioid intracellular receptor 1
Search

SIGMAR1

0.97	Sigma non-opioid intracellular receptor 1

0.66	GO:0070207	protein homotrimerization
0.65	GO:0043523	regulation of neuron apoptotic process
0.48	GO:0006869	lipid transport
0.43	GO:0038003	opioid receptor signaling pathway
0.40	GO:0007399	nervous system development
0.35	GO:0009611	response to wounding
0.33	GO:0006696	ergosterol biosynthetic process

0.50	GO:0004872	receptor activity
0.40	GO:0042802	identical protein binding
0.37	GO:0004871	signal transducer activity
0.34	GO:0016853	isomerase activity
0.33	GO:0008144	drug binding
0.32	GO:0003677	DNA binding

0.65	GO:0014069	postsynaptic density
0.61	GO:0005635	nuclear envelope
0.59	GO:0005783	endoplasmic reticulum
0.49	GO:0031968	organelle outer membrane
0.48	GO:0030426	growth cone
0.47	GO:0005811	lipid droplet
0.47	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.47	GO:0031410	cytoplasmic vesicle
0.46	GO:0045211	postsynaptic membrane
0.45	GO:0031984	organelle subcompartment

0.34

EC:5

GO:0016853

sp|O70126|AURKB_MOUSE
Aurora kinase B
Search

AURKB

0.94	Aurora kinase B-A

0.72	GO:0035404	histone-serine phosphorylation
0.67	GO:0007051	spindle organization
0.64	GO:0032467	positive regulation of cytokinesis
0.64	GO:0000278	mitotic cell cycle
0.61	GO:0031577	spindle checkpoint
0.58	GO:0070925	organelle assembly
0.58	GO:0036089	cleavage furrow formation
0.57	GO:0000280	nuclear division
0.57	GO:0002903	negative regulation of B cell apoptotic process
0.57	GO:0032091	negative regulation of protein binding

0.68	GO:0004674	protein serine/threonine kinase activity
0.64	GO:0035173	histone kinase activity
0.54	GO:0019900	kinase binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.52	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.44	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0046982	protein heterodimerization activity

0.75	GO:0032133	chromosome passenger complex
0.63	GO:0051233	spindle midzone
0.60	GO:0030496	midbody
0.59	GO:0000793	condensed chromosome
0.58	GO:0031616	spindle pole centrosome
0.56	GO:0000775	chromosome, centromeric region
0.55	GO:0005876	spindle microtubule
0.55	GO:0072686	mitotic spindle
0.54	GO:0044454	nuclear chromosome part
0.52	GO:0010369	chromocenter

0.68

GO:0004674

sp|O70131|NINJ1_MOUSE
Ninjurin-1
Search

NINJ1

0.94	Nerve injury-induced protein 1

0.85	GO:0042246	tissue regeneration
0.72	GO:0007155	cell adhesion
0.58	GO:1990384	hyaloid vascular plexus regression
0.55	GO:0001954	positive regulation of cell-matrix adhesion
0.34	GO:0007399	nervous system development

0.33

GO:0005515

protein binding

0.30

GO:0044425

membrane part

sp|O70133|DHX9_MOUSE
ATP-dependent RNA helicase A
Search

DHX9

0.84	DEAH (Asp-Glu-Ala-His) box polypeptide 9

0.62	GO:1904973	positive regulation of viral translation
0.62	GO:1905698	positive regulation of polysome binding
0.61	GO:0039695	DNA-templated viral transcription
0.61	GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity
0.61	GO:0035549	positive regulation of interferon-beta secretion
0.61	GO:0070934	CRD-mediated mRNA stabilization
0.61	GO:0046833	positive regulation of RNA export from nucleus
0.60	GO:1903608	protein localization to cytoplasmic stress granule
0.60	GO:1904469	positive regulation of tumor necrosis factor secretion
0.60	GO:1902741	positive regulation of interferon-alpha secretion

0.66	GO:0004386	helicase activity
0.62	GO:1905172	RISC complex binding
0.62	GO:1905538	polysome binding
0.61	GO:0001069	regulatory region RNA binding
0.61	GO:0045142	triplex DNA binding
0.60	GO:1990825	sequence-specific mRNA binding
0.60	GO:0061676	importin-alpha family protein binding
0.59	GO:0035613	RNA stem-loop binding
0.59	GO:0035197	siRNA binding
0.58	GO:1990841	promoter-specific chromatin binding

0.60	GO:0005726	perichromatin fibrils
0.60	GO:0097165	nuclear stress granule
0.60	GO:0070937	CRD-mediated mRNA stability complex
0.59	GO:0070578	RISC-loading complex
0.58	GO:0035068	micro-ribonucleoprotein complex
0.57	GO:0042788	polysomal ribosome
0.54	GO:0036464	cytoplasmic ribonucleoprotein granule
0.53	GO:0005813	centrosome
0.53	GO:0016604	nuclear body
0.51	GO:0015629	actin cytoskeleton

0.52

EC:3.6.1.19

GO:0047429

sp|O70137|ALX3_MOUSE
Homeobox protein aristaless-like 3
Search

ALX3

0.91	ALX homeobox protein 1

0.74	GO:0048704	embryonic skeletal system morphogenesis
0.72	GO:1904888	cranial skeletal system development
0.63	GO:0035116	embryonic hindlimb morphogenesis
0.63	GO:0035115	embryonic forelimb morphogenesis
0.59	GO:0007389	pattern specification process
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0042981	regulation of apoptotic process
0.49	GO:0001755	neural crest cell migration

0.63	GO:0043565	sequence-specific DNA binding
0.49	GO:0003700	DNA binding transcription factor activity
0.43	GO:0071837	HMG box domain binding
0.42	GO:0001012	RNA polymerase II regulatory region DNA binding
0.42	GO:0046982	protein heterodimerization activity
0.41	GO:0003690	double-stranded DNA binding
0.33	GO:0042803	protein homodimerization activity

0.60	GO:0005634	nucleus
0.42	GO:0005667	transcription factor complex
0.36	GO:0005794	Golgi apparatus
0.36	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part

sp|O70138|MMP8_MOUSE
Neutrophil collagenase
Search

0.57	Matrix metalloproteinase

0.61	GO:0006508	proteolysis
0.55	GO:0035987	endodermal cell differentiation
0.48	GO:0032461	positive regulation of protein oligomerization
0.44	GO:0030574	collagen catabolic process
0.37	GO:0022617	extracellular matrix disassembly
0.36	GO:0043312	neutrophil degranulation
0.35	GO:0001503	ossification
0.34	GO:0050900	leukocyte migration
0.34	GO:0019221	cytokine-mediated signaling pathway
0.33	GO:0016032	viral process

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.47	GO:0004252	serine-type endopeptidase activity
0.34	GO:0005509	calcium ion binding

0.74	GO:0031012	extracellular matrix
0.49	GO:0005615	extracellular space
0.41	GO:0005581	collagen trimer
0.38	GO:0042406	extrinsic component of endoplasmic reticulum membrane
0.36	GO:1904724	tertiary granule lumen
0.36	GO:0035580	specific granule lumen
0.34	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.70

GO:0004222

sp|O70139|IPKG_MOUSE
cAMP-dependent protein kinase inhibitor gamma
Search

PKIG

0.93	cAMP-dependent protein kinase inhibitor gamma

0.82	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.63	GO:0042308	negative regulation of protein import into nucleus
0.58	GO:0000122	negative regulation of transcription by RNA polymerase II
0.54	GO:2000479	regulation of cAMP-dependent protein kinase activity
0.50	GO:0016310	phosphorylation
0.41	GO:1904355	positive regulation of telomere capping
0.40	GO:0051973	positive regulation of telomerase activity
0.40	GO:0032212	positive regulation of telomere maintenance via telomerase
0.39	GO:0007165	signal transduction

0.86	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.52	GO:0016301	kinase activity
0.34	GO:0005515	protein binding

0.43	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm

sp|O70145|NCF2_MOUSE
Neutrophil cytosol factor 2
Search

NCF2

0.95	Neutrophil cytosolic factor 2

0.86	GO:0045730	respiratory burst
0.83	GO:0006909	phagocytosis
0.73	GO:0043085	positive regulation of catalytic activity
0.58	GO:0042554	superoxide anion generation
0.41	GO:0055114	oxidation-reduction process
0.36	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.36	GO:0006968	cellular defense response
0.36	GO:0006742	NADP catabolic process
0.36	GO:0034616	response to laminar fluid shear stress
0.36	GO:0055093	response to hyperoxia

0.86	GO:0016176	superoxide-generating NADPH oxidase activator activity
0.58	GO:0016175	superoxide-generating NADPH oxidase activity
0.58	GO:0048365	Rac GTPase binding
0.56	GO:0008022	protein C-terminus binding
0.33	GO:0009055	electron transfer activity
0.33	GO:0017124	SH3 domain binding

0.85	GO:0043020	NADPH oxidase complex
0.57	GO:0001669	acrosomal vesicle
0.51	GO:0005730	nucleolus
0.49	GO:0005829	cytosol
0.36	GO:0032010	phagolysosome
0.34	GO:0005885	Arp2/3 protein complex

0.58

EC:1.6.3

GO:0016175

sp|O70146|TESK1_MOUSE
Dual specificity testis-specific protein kinase 1
Search

TESK1

0.90	Dual specificity testis-specific protein kinase 1

0.63	GO:0006468	protein phosphorylation
0.43	GO:0035556	intracellular signal transduction
0.41	GO:0031953	negative regulation of protein autophosphorylation
0.41	GO:0051496	positive regulation of stress fiber assembly
0.40	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.39	GO:0007283	spermatogenesis
0.39	GO:0018212	peptidyl-tyrosine modification
0.38	GO:0032880	regulation of protein localization

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.43	GO:0004871	signal transducer activity
0.40	GO:0008022	protein C-terminus binding
0.39	GO:0019901	protein kinase binding

0.38	GO:0016604	nuclear body
0.38	GO:0031410	cytoplasmic vesicle
0.34	GO:0005829	cytosol

sp|O70152|DPM1_MOUSE
Dolichol-phosphate mannosyltransferase subunit 1
Search

DPM1

0.52	Dolichol-phosphate mannosyltransferase dolichol-phosphate mannose synthase dolichyl-phosphate beta-d-mannosyltransferase mannose-p-dolichol synthase mpd synthase dpm synthase

0.45	GO:0097502	mannosylation
0.44	GO:0061061	muscle structure development
0.44	GO:0006506	GPI anchor biosynthetic process
0.43	GO:0006493	protein O-linked glycosylation
0.43	GO:0019348	dolichol metabolic process
0.36	GO:0019673	GDP-mannose metabolic process
0.36	GO:0018279	protein N-linked glycosylation via asparagine

0.62	GO:0016757	transferase activity, transferring glycosyl groups
0.37	GO:0005537	mannose binding
0.37	GO:0043178	alcohol binding
0.34	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003677	DNA binding

0.41	GO:0005783	endoplasmic reticulum
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.41	GO:0033185	dolichol-phosphate-mannose synthase complex
0.40	GO:0031984	organelle subcompartment
0.35	GO:0005634	nucleus
0.30	GO:0044425	membrane part

0.62

GO:0016757

sp|O70157|TOP3A_MOUSE
DNA topoisomerase 3-alpha
Search

TOP3A

0.56	DNA topoisomerase

0.72	GO:0006265	DNA topological change
0.36	GO:0000732	strand displacement
0.35	GO:1901796	regulation of signal transduction by p53 class mediator
0.35	GO:0000731	DNA synthesis involved in DNA repair
0.35	GO:0051321	meiotic cell cycle
0.34	GO:0006260	DNA replication
0.33	GO:0045892	negative regulation of transcription, DNA-templated

0.76	GO:0003917	DNA topoisomerase type I activity
0.62	GO:0008270	zinc ion binding
0.55	GO:0003677	DNA binding
0.33	GO:0005515	protein binding

0.67	GO:0005694	chromosome
0.56	GO:0016605	PML body

0.76

EC:5.99.1.2

GO:0003917

sp|O70161|PI51C_MOUSE
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
Search

PIP5K1C

0.96	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma

0.75	GO:0046854	phosphatidylinositol phosphorylation
0.38	GO:0006909	phagocytosis
0.38	GO:0070527	platelet aggregation
0.38	GO:0006661	phosphatidylinositol biosynthetic process
0.37	GO:0006887	exocytosis
0.37	GO:0007016	cytoskeletal anchoring at plasma membrane
0.37	GO:0007409	axonogenesis
0.36	GO:0006935	chemotaxis
0.35	GO:0048488	synaptic vesicle endocytosis
0.35	GO:1990266	neutrophil migration

0.81	GO:0016307	phosphatidylinositol phosphate kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:1990147	talin binding
0.36	GO:0052812	phosphatidylinositol-3,4-bisphosphate 5-kinase activity

0.49	GO:0010008	endosome membrane
0.45	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.39	GO:0001931	uropod
0.39	GO:0001891	phagocytic cup
0.39	GO:0032587	ruffle membrane
0.38	GO:0005925	focal adhesion
0.35	GO:0098793	presynapse
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0016307

sp|O70165|FCN1_MOUSE
Ficolin-1
Search

FCN2

0.88	Ficolin (Collagen/fibrinogen domain containing) 1

0.71	GO:0072376	protein activation cascade
0.70	GO:0006959	humoral immune response
0.66	GO:0002253	activation of immune response
0.65	GO:0045087	innate immune response
0.64	GO:0043654	recognition of apoptotic cell
0.62	GO:0050714	positive regulation of protein secretion
0.62	GO:0002252	immune effector process
0.59	GO:2000482	regulation of interleukin-8 secretion
0.58	GO:0051240	positive regulation of multicellular organismal process
0.57	GO:0030168	platelet activation

0.63	GO:0033691	sialic acid binding
0.57	GO:0038187	pattern recognition receptor activity
0.56	GO:0005102	receptor binding
0.55	GO:0030674	protein binding, bridging
0.54	GO:0030246	carbohydrate binding
0.53	GO:0003823	antigen binding
0.49	GO:0050839	cell adhesion molecule binding
0.49	GO:0043394	proteoglycan binding
0.49	GO:0048306	calcium-dependent protein binding
0.47	GO:0038023	signaling receptor activity

0.61	GO:0009897	external side of plasma membrane
0.59	GO:0005581	collagen trimer
0.59	GO:0005577	fibrinogen complex
0.53	GO:0019897	extrinsic component of plasma membrane
0.52	GO:0031091	platelet alpha granule
0.48	GO:0072562	blood microparticle
0.47	GO:0005938	cell cortex
0.42	GO:0034774	secretory granule lumen
0.42	GO:0070062	extracellular exosome
0.41	GO:1904813	ficolin-1-rich granule lumen

0.39

GO:0004252

sp|O70166|STMN3_MOUSE
Stathmin-3
Search

STMN3

0.85

Stathmin

0.84	GO:0031110	regulation of microtubule polymerization or depolymerization
0.76	GO:0031122	cytoplasmic microtubule organization
0.72	GO:0031175	neuron projection development
0.58	GO:0035021	negative regulation of Rac protein signal transduction
0.51	GO:0007019	microtubule depolymerization
0.50	GO:0043087	regulation of GTPase activity
0.47	GO:1990090	cellular response to nerve growth factor stimulus
0.46	GO:1901881	positive regulation of protein depolymerization
0.46	GO:0010977	negative regulation of neuron projection development
0.46	GO:0010976	positive regulation of neuron projection development

0.68	GO:0015631	tubulin binding
0.50	GO:0019904	protein domain specific binding
0.47	GO:0048306	calcium-dependent protein binding
0.35	GO:0008022	protein C-terminus binding
0.32	GO:0003713	transcription coactivator activity
0.31	GO:0003677	DNA binding

0.51	GO:0043005	neuron projection
0.48	GO:0030427	site of polarized growth
0.47	GO:0005737	cytoplasm
0.47	GO:0120038	plasma membrane bounded cell projection part
0.45	GO:0030027	lamellipodium
0.45	GO:0043025	neuronal cell body
0.39	GO:0012505	endomembrane system
0.37	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0031982	vesicle
0.30	GO:0016020	membrane

sp|O70167|P3C2G_MOUSE
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma
Search

PIK3C2G

0.96	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma

0.81	GO:0048015	phosphatidylinositol-mediated signaling
0.75	GO:0046854	phosphatidylinositol phosphorylation
0.53	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process
0.47	GO:0016477	cell migration
0.43	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis
0.39	GO:0006897	endocytosis
0.39	GO:0048268	clathrin coat assembly
0.39	GO:0006935	chemotaxis
0.38	GO:0039694	viral RNA genome replication
0.38	GO:0001525	angiogenesis

0.75	GO:0035004	phosphatidylinositol 3-kinase activity
0.74	GO:0035091	phosphatidylinositol binding
0.67	GO:0016307	phosphatidylinositol phosphate kinase activity
0.53	GO:0052742	phosphatidylinositol kinase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003735	structural constituent of ribosome

0.49	GO:0005942	phosphatidylinositol 3-kinase complex
0.45	GO:0005622	intracellular
0.40	GO:0005886	plasma membrane
0.39	GO:0031982	vesicle
0.36	GO:0012505	endomembrane system
0.34	GO:0031975	envelope
0.34	GO:0044422	organelle part
0.33	GO:0043230	extracellular organelle
0.33	GO:1990904	ribonucleoprotein complex
0.33	GO:0005615	extracellular space

0.75

GO:0035004

sp|O70169|PRS39_MOUSE
Inactive serine protease 39
Search

0.97	Testicular serine protease 2

0.61	GO:0006508	proteolysis
0.47	GO:0042730	fibrinolysis
0.46	GO:0007596	blood coagulation
0.45	GO:0048771	tissue remodeling
0.41	GO:0052213	interaction with symbiont via secreted substance involved in symbiotic interaction
0.41	GO:0052212	modification of morphology or physiology of other organism via secreted substance involved in symbiotic interaction
0.41	GO:0006898	receptor-mediated endocytosis
0.40	GO:0060707	trophoblast giant cell differentiation
0.40	GO:0060716	labyrinthine layer blood vessel development
0.40	GO:0051919	positive regulation of fibrinolysis

0.69	GO:0004252	serine-type endopeptidase activity
0.43	GO:0005044	scavenger receptor activity
0.41	GO:1904854	proteasome core complex binding
0.40	GO:1990405	protein antigen binding
0.40	GO:0034185	apolipoprotein binding
0.40	GO:0019900	kinase binding
0.39	GO:0004222	metalloendopeptidase activity
0.38	GO:0019904	protein domain specific binding
0.38	GO:0051087	chaperone binding
0.37	GO:0005102	receptor binding

0.47	GO:0005576	extracellular region
0.41	GO:0030141	secretory granule
0.41	GO:0019897	extrinsic component of plasma membrane
0.40	GO:0097223	sperm part
0.38	GO:0009897	external side of plasma membrane
0.37	GO:0031226	intrinsic component of plasma membrane
0.36	GO:0044218	other organism cell membrane
0.35	GO:0031225	anchored component of membrane
0.33	GO:0043204	perikaryon
0.33	GO:0060205	cytoplasmic vesicle lumen

0.69

GO:0004252

sp|O70172|PI42A_MOUSE
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
Search

PIP4K2A

0.95	Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha

0.75	GO:0046854	phosphatidylinositol phosphorylation
0.70	GO:2000786	positive regulation of autophagosome assembly
0.64	GO:0035855	megakaryocyte development
0.45	GO:0048634	regulation of muscle organ development

0.82	GO:0016307	phosphatidylinositol phosphate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0042803	protein homodimerization activity

0.66	GO:0005776	autophagosome
0.45	GO:0005654	nucleoplasm

0.82

GO:0016307

sp|O70174|ACHA4_MOUSE
Neuronal acetylcholine receptor subunit alpha-4
Search

CHRNA4

0.94	Cholinergic receptor nicotinic alpha 4 subunit

0.78	GO:0060079	excitatory postsynaptic potential
0.74	GO:0035094	response to nicotine
0.71	GO:0007271	synaptic transmission, cholinergic
0.70	GO:0060080	inhibitory postsynaptic potential
0.68	GO:0014059	regulation of dopamine secretion
0.68	GO:0035640	exploration behavior
0.68	GO:0007585	respiratory gaseous exchange
0.67	GO:0051899	membrane depolarization
0.67	GO:0019233	sensory perception of pain
0.66	GO:0001508	action potential

0.81	GO:0022848	acetylcholine-gated cation-selective channel activity
0.71	GO:0015464	acetylcholine receptor activity
0.57	GO:0042166	acetylcholine binding

0.77	GO:0045211	postsynaptic membrane
0.73	GO:0005892	acetylcholine-gated channel complex
0.72	GO:0030054	cell junction
0.64	GO:0009897	external side of plasma membrane

sp|O70176|PACA_MOUSE
Pituitary adenylate cyclase-activating polypeptide
Search

ADCYAP1

0.94	Pituitary adenylate cyclase-activating polypeptide

0.75	GO:0010469	regulation of receptor activity
0.60	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production
0.59	GO:0007218	neuropeptide signaling pathway
0.57	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.57	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.57	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.54	GO:0007399	nervous system development
0.54	GO:0045860	positive regulation of protein kinase activity
0.53	GO:0120036	plasma membrane bounded cell projection organization
0.53	GO:0043547	positive regulation of GTPase activity

0.79	GO:0005179	hormone activity
0.60	GO:0051428	peptide hormone receptor binding
0.44	GO:0005057	signal transducer activity, downstream of receptor
0.44	GO:0031858	pituitary adenylate cyclase-activating polypeptide receptor binding

0.66	GO:0005576	extracellular region
0.41	GO:0043195	terminal bouton
0.38	GO:0005622	intracellular
0.37	GO:0070852	cell body fiber
0.36	GO:0043204	perikaryon
0.30	GO:0031224	intrinsic component of membrane

sp|O70191|ATF5_MOUSE
Cyclic AMP-dependent transcription factor ATF-5
Search

ATF5

0.95	Cyclic AMP-dependent transcription factor ATF-5

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.66	GO:0045444	fat cell differentiation
0.65	GO:0046605	regulation of centrosome cycle
0.65	GO:0021891	olfactory bulb interneuron development
0.64	GO:0021930	cerebellar granule cell precursor proliferation
0.64	GO:1902750	negative regulation of cell cycle G2/M phase transition
0.62	GO:0043066	negative regulation of apoptotic process
0.61	GO:0008285	negative regulation of cell proliferation
0.60	GO:0035264	multicellular organism growth
0.59	GO:0007623	circadian rhythm

0.61	GO:0003700	DNA binding transcription factor activity
0.61	GO:0003682	chromatin binding
0.60	GO:0019900	kinase binding
0.60	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.58	GO:0015631	tubulin binding
0.39	GO:0003714	transcription corepressor activity
0.39	GO:0031072	heat shock protein binding

0.60	GO:0005813	centrosome
0.55	GO:0005654	nucleoplasm
0.55	GO:0005667	transcription factor complex
0.54	GO:0005829	cytosol

sp|O70194|EIF3D_MOUSE
Eukaryotic translation initiation factor 3 subunit D
Search

EIF3D

0.73	Eukaryotic translation initiation factor 3 subunit D

0.80	GO:0002191	cap-dependent translational initiation
0.72	GO:0001731	formation of translation preinitiation complex
0.71	GO:0006446	regulation of translational initiation
0.59	GO:0075525	viral translational termination-reinitiation
0.58	GO:1902416	positive regulation of mRNA binding
0.58	GO:0075522	IRES-dependent viral translational initiation
0.57	GO:0001732	formation of cytoplasmic translation initiation complex
0.52	GO:0045727	positive regulation of translation
0.34	GO:0043044	ATP-dependent chromatin remodeling
0.34	GO:0006414	translational elongation

0.81	GO:0098808	mRNA cap binding
0.72	GO:0003743	translation initiation factor activity
0.34	GO:0042393	histone binding
0.34	GO:0003746	translation elongation factor activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0016887	ATPase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.77	GO:0005852	eukaryotic translation initiation factor 3 complex
0.71	GO:0016282	eukaryotic 43S preinitiation complex
0.71	GO:0033290	eukaryotic 48S preinitiation complex
0.34	GO:0016514	SWI/SNF complex
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.33

GO:0016887

sp|O70200|AIF1_MOUSE
Allograft inflammatory factor 1
Search

AIF1

0.96	Ionized calcium binding adapter molecule 1

0.62	GO:0071673	positive regulation of smooth muscle cell chemotaxis
0.59	GO:0016601	Rac protein signal transduction
0.58	GO:2000406	positive regulation of T cell migration
0.58	GO:0090026	positive regulation of monocyte chemotaxis
0.58	GO:0071672	negative regulation of smooth muscle cell chemotaxis
0.58	GO:0097178	ruffle assembly
0.58	GO:0048661	positive regulation of smooth muscle cell proliferation
0.57	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.57	GO:0071346	cellular response to interferon-gamma
0.57	GO:0006911	phagocytosis, engulfment

0.70	GO:0051015	actin filament binding
0.67	GO:0005509	calcium ion binding

0.59	GO:0005884	actin filament
0.58	GO:0032587	ruffle membrane
0.58	GO:0001891	phagocytic cup
0.56	GO:0030027	lamellipodium
0.52	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.43	GO:0005925	focal adhesion
0.42	GO:0043204	perikaryon
0.36	GO:0070062	extracellular exosome

sp|O70201|BIRC5_MOUSE
Baculoviral IAP repeat-containing protein 5
Search

BIRC5

0.94	Baculoviral IAP repeat-containing protein 5

0.76	GO:0043066	negative regulation of apoptotic process
0.75	GO:0043523	regulation of neuron apoptotic process
0.72	GO:0061469	regulation of type B pancreatic cell proliferation
0.70	GO:0000226	microtubule cytoskeleton organization
0.69	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus
0.67	GO:0007346	regulation of mitotic cell cycle
0.67	GO:1901215	negative regulation of neuron death
0.67	GO:0097340	inhibition of cysteine-type endopeptidase activity
0.63	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.62	GO:0140014	mitotic nuclear division

0.64	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.56	GO:0004842	ubiquitin-protein transferase activity
0.55	GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0008017	microtubule binding
0.46	GO:0008536	Ran GTPase binding
0.44	GO:0008270	zinc ion binding
0.43	GO:0046965	retinoid X receptor binding
0.42	GO:0051087	chaperone binding
0.42	GO:0046982	protein heterodimerization activity

0.59	GO:0032133	chromosome passenger complex
0.58	GO:0030496	midbody
0.56	GO:0000777	condensed chromosome kinetochore
0.56	GO:0031021	interphase microtubule organizing center
0.55	GO:0005819	spindle
0.53	GO:0005881	cytoplasmic microtubule
0.53	GO:0005814	centriole
0.51	GO:0005634	nucleus
0.47	GO:0005829	cytosol
0.40	GO:0070013	intracellular organelle lumen

0.33	EC:3	GO:0016787
0.56	KEGG:R03876	GO:0004842

sp|O70209|PDLI3_MOUSE
PDZ and LIM domain protein 3
Search

PDLIM3

0.88	Actinin-associated LIM protein 2

0.45	GO:0007507	heart development
0.44	GO:0007015	actin filament organization
0.34	GO:0016311	dephosphorylation

0.54	GO:0046872	metal ion binding
0.47	GO:0008307	structural constituent of muscle
0.43	GO:0008092	cytoskeletal protein binding
0.35	GO:0004035	alkaline phosphatase activity

0.45	GO:0015629	actin cytoskeleton
0.42	GO:0030018	Z disc
0.38	GO:0030027	lamellipodium
0.38	GO:0005925	focal adhesion
0.36	GO:0044430	cytoskeletal part

0.35

EC:3.1.3.1

GO:0004035

sp|O70218|HMX1_MOUSE
Homeobox protein HMX1
Search

HMX1

0.71	Homeobox protein HMX1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:1902679	negative regulation of RNA biosynthetic process
0.47	GO:0042472	inner ear morphogenesis
0.47	GO:0050885	neuromuscular process controlling balance
0.46	GO:0007566	embryo implantation
0.46	GO:0060135	maternal process involved in female pregnancy
0.45	GO:0007399	nervous system development
0.45	GO:0060322	head development

0.64	GO:0043565	sequence-specific DNA binding
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.52	GO:0003690	double-stranded DNA binding

0.61

GO:0005634

nucleus

sp|O70220|FOXQ1_MOUSE
Forkhead box protein Q1
Search

FOXQ1

0.94	Winged helix/forkhead transcription factor FoxQ1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0048856	anatomical structure development
0.48	GO:0032501	multicellular organismal process
0.46	GO:0030154	cell differentiation
0.46	GO:1902679	negative regulation of RNA biosynthetic process
0.43	GO:0040018	positive regulation of multicellular organism growth
0.40	GO:1902747	negative regulation of lens fiber cell differentiation
0.40	GO:2001111	positive regulation of lens epithelial cell proliferation

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.49	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0003690	double-stranded DNA binding
0.35	GO:0001106	RNA polymerase II transcription corepressor activity
0.33	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.33	GO:0042302	structural constituent of cuticle
0.33	GO:0004725	protein tyrosine phosphatase activity
0.32	GO:0005515	protein binding
0.32	GO:0008168	methyltransferase activity

0.61	GO:0005634	nucleus
0.37	GO:0005667	transcription factor complex
0.30	GO:0016021	integral component of membrane

0.33

EC:3.1.3

GO:0008138

sp|O70228|ATP9A_MOUSE
Probable phospholipid-transporting ATPase IIA
Search

ATP9A

0.59	Phospholipid-transporting ATPase

0.79	GO:0045332	phospholipid translocation
0.47	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.43	GO:0006897	endocytosis

0.79	GO:0004012	phospholipid-translocating ATPase activity
0.64	GO:0000287	magnesium ion binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.78	GO:0005802	trans-Golgi network
0.73	GO:0005768	endosome
0.52	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005886	plasma membrane
0.35	GO:0044433	cytoplasmic vesicle part
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:3.6.3.1

GO:0004012

sp|O70230|ZN143_MOUSE
Zinc finger protein 143
Search

ZNF143

0.86	Selenocysteine tRNA activating factor

0.39	GO:0045893	positive regulation of transcription, DNA-templated
0.38	GO:0006351	transcription, DNA-templated
0.37	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0006886	intracellular protein transport

0.51	GO:0003676	nucleic acid binding
0.39	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0046872	metal ion binding
0.35	GO:0008536	Ran GTPase binding

0.38

GO:0005634

nucleus

sp|O70237|GFI1B_MOUSE
Zinc finger protein Gfi-1b
Search

GFI1B

0.84	Growth factor independent 1B transcriptional repressor

0.59	GO:0051569	regulation of histone H3-K4 methylation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0030097	hemopoiesis
0.52	GO:0070105	positive regulation of interleukin-6-mediated signaling pathway
0.51	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity
0.49	GO:0034121	regulation of toll-like receptor signaling pathway
0.48	GO:0010977	negative regulation of neuron projection development
0.48	GO:0071222	cellular response to lipopolysaccharide

0.69	GO:0001085	RNA polymerase II transcription factor binding
0.51	GO:0003676	nucleic acid binding
0.48	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.74	GO:0016363	nuclear matrix
0.63	GO:0005667	transcription factor complex
0.47	GO:0017053	transcriptional repressor complex
0.46	GO:0016604	nuclear body

tr|O70238|O70238_MOUSE
Homeobox protein PSX
Search

0.97	Homeobox protein GPBOX

0.47	GO:0010628	positive regulation of gene expression
0.37	GO:0098869	cellular oxidant detoxification
0.34	GO:0055114	oxidation-reduction process

0.53	GO:0003677	DNA binding
0.38	GO:0016787	hydrolase activity
0.37	GO:0016209	antioxidant activity
0.35	GO:0030246	carbohydrate binding
0.34	GO:0016491	oxidoreductase activity

0.58	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.38

GO:0016787

sp|O70250|PGAM2_MOUSE
Phosphoglycerate mutase 2
Search

PGAM2

0.48	Phosphoglycerate mutase

0.69	GO:0006757	ATP generation from ADP
0.68	GO:0006090	pyruvate metabolic process
0.67	GO:0016052	carbohydrate catabolic process
0.66	GO:0019362	pyridine nucleotide metabolic process
0.56	GO:0043456	regulation of pentose-phosphate shunt
0.54	GO:0006941	striated muscle contraction
0.51	GO:0007219	Notch signaling pathway
0.47	GO:0019319	hexose biosynthetic process
0.47	GO:0006006	glucose metabolic process
0.42	GO:0045730	respiratory burst

0.83	GO:0004082	bisphosphoglycerate mutase activity
0.77	GO:0004619	phosphoglycerate mutase activity
0.40	GO:0019901	protein kinase binding
0.36	GO:0016787	hydrolase activity
0.34	GO:0048037	cofactor binding
0.33	GO:0034061	DNA polymerase activity
0.32	GO:0003677	DNA binding

0.46	GO:0005829	cytosol
0.45	GO:0043209	myelin sheath
0.38	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.30	GO:0016020	membrane

0.83

EC:5.4.2.4

GO:0004082

sp|O70251|EF1B_MOUSE
Elongation factor 1-beta
Search

EEF1B2

0.66	Eukaryotic translation elongation factor 1 beta 2

0.70	GO:0006414	translational elongation
0.37	GO:0045471	response to ethanol

0.71	GO:0003746	translation elongation factor activity
0.34	GO:0005515	protein binding

0.83	GO:0005853	eukaryotic translation elongation factor 1 complex
0.44	GO:0005783	endoplasmic reticulum
0.34	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|O70252|HMOX2_MOUSE
Heme oxygenase 2
Search

HMOX2

0.58	Heme oxygenase

0.82	GO:0006788	heme oxidation
0.51	GO:0042167	heme catabolic process
0.46	GO:0055072	iron ion homeostasis
0.45	GO:0006979	response to oxidative stress
0.41	GO:0001666	response to hypoxia
0.40	GO:0002246	wound healing involved in inflammatory response
0.40	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron
0.40	GO:0071243	cellular response to arsenic-containing substance
0.39	GO:0072719	cellular response to cisplatin
0.39	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

0.82	GO:0004392	heme oxygenase (decyclizing) activity
0.47	GO:0046872	metal ion binding
0.42	GO:0020037	heme binding
0.37	GO:0042803	protein homodimerization activity
0.32	GO:0004871	signal transducer activity

0.40	GO:0005783	endoplasmic reticulum
0.38	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0035579	specific granule membrane
0.35	GO:0005634	nucleus
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.82

EC:1.14.99.3

GO:0004392

sp|O70255|MPZL2_MOUSE
Myelin protein zero-like protein 2
Search

MPZL2

0.97	Myelin protein zero like 2

0.77	GO:0098609	cell-cell adhesion
0.39	GO:0033077	T cell differentiation in thymus
0.34	GO:0009653	anatomical structure morphogenesis

0.37

GO:0042802

identical protein binding

0.34	GO:0005886	plasma membrane
0.34	GO:0005856	cytoskeleton
0.30	GO:0044425	membrane part

sp|O70258|SGCE_MOUSE
Epsilon-sarcoglycan
Search

SGCE

0.66	Brain epsilon-sarcoglycan

0.46	GO:0003012	muscle system process
0.42	GO:0061024	membrane organization
0.36	GO:0007517	muscle organ development
0.35	GO:0001822	kidney development
0.35	GO:0014706	striated muscle tissue development
0.35	GO:0007160	cell-matrix adhesion
0.34	GO:0007420	brain development

0.41	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding

0.85	GO:0016012	sarcoglycan complex
0.55	GO:0032590	dendrite membrane
0.47	GO:0005794	Golgi apparatus
0.41	GO:0042383	sarcolemma
0.38	GO:0005856	cytoskeleton
0.35	GO:0005887	integral component of plasma membrane

sp|O70263|LNX1_MOUSE
E3 ubiquitin-protein ligase LNX
Search

LNX1

0.92	E3 ubiquitin-protein ligase LNX

0.48	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.47	GO:0051260	protein homooligomerization

0.61	GO:0016874	ligase activity
0.49	GO:0030165	PDZ domain binding
0.47	GO:0046872	metal ion binding
0.45	GO:0004842	ubiquitin-protein transferase activity

0.37

GO:0005737

cytoplasm

0.61	EC:6	GO:0016874
0.45	KEGG:R03876	GO:0004842

sp|O70273|EHF_MOUSE
ETS homologous factor
Search

EHF

0.97	ETS like proteinous factor

0.84	GO:0050673	epithelial cell proliferation
0.80	GO:0030855	epithelial cell differentiation
0.76	GO:0006366	transcription by RNA polymerase II
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:1902680	positive regulation of RNA biosynthetic process
0.43	GO:0006954	inflammatory response
0.36	GO:0060056	mammary gland involution
0.36	GO:0001824	blastocyst development

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.36	GO:0003713	transcription coactivator activity

0.61	GO:0005634	nucleus
0.51	GO:0005794	Golgi apparatus
0.48	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.34	GO:0005829	cytosol

sp|O70274|TP4A2_MOUSE
Protein tyrosine phosphatase type IVA 2
Search

PTP4A2

0.92	Tyrosine phosphatase type IVA

0.72	GO:0006470	protein dephosphorylation
0.45	GO:0030335	positive regulation of cell migration
0.37	GO:0007275	multicellular organism development
0.36	GO:0007049	cell cycle
0.34	GO:0043687	post-translational protein modification

0.72	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.46	GO:0009898	cytoplasmic side of plasma membrane
0.41	GO:0005634	nucleus
0.41	GO:0005769	early endosome
0.38	GO:0070062	extracellular exosome
0.38	GO:0005819	spindle
0.37	GO:0005783	endoplasmic reticulum
0.33	GO:0005829	cytosol

0.72

GO:0004721

sp|O70279|DGC14_MOUSE
Protein DGCR14
Search

ESS2

0.97	DiGeorge syndrome critical region gene 14

0.44	GO:0007399	nervous system development
0.41	GO:0008380	RNA splicing
0.40	GO:0006397	mRNA processing

0.36	GO:0005515	protein binding
0.35	GO:0003677	DNA binding

0.80	GO:0071013	catalytic step 2 spliceosome
0.30	GO:0031224	intrinsic component of membrane

sp|O70281|TPST1_MOUSE
Protein-tyrosine sulfotransferase 1
Search

TPST1

0.97	Tyrosylprotein sulfotransferase 1

0.82	GO:0006478	peptidyl-tyrosine sulfation
0.35	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.34	GO:0006954	inflammatory response

0.83	GO:0008476	protein-tyrosine sulfotransferase activity
0.50	GO:0042803	protein homodimerization activity

0.53	GO:0030173	integral component of Golgi membrane
0.35	GO:0005783	endoplasmic reticulum

0.83

EC:2.8.2.20

GO:0008476

sp|O70283|WNT2B_MOUSE
Protein Wnt-2b
Search

sp|O70291|GRK4_MOUSE
G protein-coupled receptor kinase 4
Search

GRK6

0.69	G protein-coupled receptor kinase

0.63	GO:0006468	protein phosphorylation
0.60	GO:0007165	signal transduction
0.49	GO:0031623	receptor internalization
0.38	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.38	GO:0022401	negative adaptation of signaling pathway
0.35	GO:0198738	cell-cell signaling by wnt

0.85	GO:0004703	G-protein coupled receptor kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0047696	beta-adrenergic receptor kinase activity
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0050254	rhodopsin kinase activity
0.34	GO:0005515	protein binding

0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.36	GO:0005938	cell cortex
0.35	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane

0.85

EC:2.7.11.16

GO:0004703

sp|O70293|GRK6_MOUSE
G protein-coupled receptor kinase 6
Search

GRK6

0.69	G protein-coupled receptor kinase

0.63	GO:0006468	protein phosphorylation
0.60	GO:0007165	signal transduction
0.37	GO:0198738	cell-cell signaling by wnt
0.36	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.36	GO:0035469	determination of pancreatic left/right asymmetry
0.36	GO:1902017	regulation of cilium assembly
0.36	GO:0009968	negative regulation of signal transduction
0.36	GO:0001947	heart looping
0.35	GO:0010360	negative regulation of anion channel activity
0.35	GO:0032006	regulation of TOR signaling

0.85	GO:0004703	G-protein coupled receptor kinase activity
0.57	GO:0047696	beta-adrenergic receptor kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.34	GO:0005886	plasma membrane
0.33	GO:0005829	cytosol

0.85

EC:2.7.11.16

GO:0004703

sp|O70299|MB211_MOUSE
Putative nucleotidyltransferase MAB21L1
Search

MAB21L1

0.96	Mab-21 like 1

0.81	GO:0043010	camera-type eye development
0.79	GO:0008284	positive regulation of cell proliferation
0.42	GO:0010172	embryonic body morphogenesis

0.61	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm

sp|O70300|PSPN_MOUSE
Persephin
Search

PSPN

0.97

Persephin

0.76	GO:0010469	regulation of receptor activity
0.48	GO:0001658	branching involved in ureteric bud morphogenesis
0.39	GO:0007411	axon guidance
0.39	GO:0000165	MAPK cascade
0.39	GO:0007417	central nervous system development

0.78	GO:0008083	growth factor activity
0.38	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.66	GO:0005576	extracellular region
0.33	GO:0005622	intracellular

sp|O70302|CIDEA_MOUSE
Cell death activator CIDE-A
Search

CIDEA

0.91	Cell death activator CIDE-A

0.77	GO:0006915	apoptotic process
0.77	GO:0019915	lipid storage
0.43	GO:0034389	lipid particle organization
0.42	GO:0035634	response to stilbenoid
0.42	GO:1902510	regulation of apoptotic DNA fragmentation
0.42	GO:0010890	positive regulation of sequestering of triglyceride
0.42	GO:1900118	negative regulation of execution phase of apoptosis
0.42	GO:0050995	negative regulation of lipid catabolic process
0.41	GO:0001659	temperature homeostasis
0.41	GO:0032720	negative regulation of tumor necrosis factor production

0.39

GO:0042803

protein homodimerization activity

0.76	GO:0005811	lipid droplet
0.39	GO:0005829	cytosol
0.39	GO:0005634	nucleus
0.38	GO:0005783	endoplasmic reticulum
0.36	GO:0044429	mitochondrial part
0.36	GO:0031967	organelle envelope
0.30	GO:0031224	intrinsic component of membrane

sp|O70303|CIDEB_MOUSE
Cell death activator CIDE-B
Search

CIDEB

0.84	Cell death inducing DFFA like effector c

0.78	GO:0006915	apoptotic process
0.72	GO:0097202	activation of cysteine-type endopeptidase activity
0.70	GO:0090200	positive regulation of release of cytochrome c from mitochondria
0.43	GO:0019915	lipid storage
0.41	GO:0035634	response to stilbenoid
0.41	GO:1902510	regulation of apoptotic DNA fragmentation
0.41	GO:0010890	positive regulation of sequestering of triglyceride
0.41	GO:1900118	negative regulation of execution phase of apoptosis
0.40	GO:0050995	negative regulation of lipid catabolic process
0.40	GO:0001659	temperature homeostasis

0.61	GO:0042802	identical protein binding
0.37	GO:0046983	protein dimerization activity

0.64	GO:0048471	perinuclear region of cytoplasm
0.56	GO:0005811	lipid droplet
0.56	GO:0005829	cytosol
0.36	GO:0005740	mitochondrial envelope
0.36	GO:0005634	nucleus

sp|O70305|ATX2_MOUSE
Ataxin-2
Search

ATXN2

0.96	Ataxin-2 isoform A

0.83	GO:0002091	negative regulation of receptor internalization
0.83	GO:0034063	stress granule assembly
0.79	GO:0033962	cytoplasmic mRNA processing body assembly
0.67	GO:0010603	regulation of cytoplasmic mRNA processing body assembly
0.46	GO:0021702	cerebellar Purkinje cell differentiation
0.46	GO:0040015	negative regulation of multicellular organism growth
0.45	GO:0050905	neuromuscular process
0.43	GO:0048812	neuron projection morphogenesis
0.43	GO:0048872	homeostasis of number of cells
0.38	GO:0051236	establishment of RNA localization

0.79	GO:0005154	epidermal growth factor receptor binding
0.75	GO:0008022	protein C-terminus binding
0.49	GO:0003723	RNA binding
0.47	GO:0050692	DBD domain binding
0.42	GO:0008270	zinc ion binding
0.33	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

0.77	GO:0010494	cytoplasmic stress granule
0.75	GO:0005844	polysome
0.72	GO:0005802	trans-Golgi network
0.72	GO:0048471	perinuclear region of cytoplasm
0.64	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:1.1.1

GO:0016616

sp|O70306|TBX15_MOUSE
T-box transcription factor TBX15
Search

TBX15

0.93	T-box containing transcription factor

0.58	GO:0048701	embryonic cranial skeleton morphogenesis
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0006351	transcription, DNA-templated
0.56	GO:0010468	regulation of gene expression
0.50	GO:0051253	negative regulation of RNA metabolic process
0.50	GO:0010558	negative regulation of macromolecule biosynthetic process
0.50	GO:0031327	negative regulation of cellular biosynthetic process
0.37	GO:0072001	renal system development

0.61	GO:0003700	DNA binding transcription factor activity
0.59	GO:0001106	RNA polymerase II transcription corepressor activity
0.55	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0042803	protein homodimerization activity
0.52	GO:0046982	protein heterodimerization activity

0.63

GO:0070722

Tle3-Aes complex

sp|O70309|ITB5_MOUSE
Integrin beta-5
Search

ITGB5

0.68	Integrin beta

0.80	GO:0007229	integrin-mediated signaling pathway
0.72	GO:0007155	cell adhesion
0.59	GO:0043149	stress fiber assembly
0.57	GO:0035987	endodermal cell differentiation
0.56	GO:0007179	transforming growth factor beta receptor signaling pathway
0.37	GO:0060055	angiogenesis involved in wound healing
0.37	GO:0007044	cell-substrate junction assembly
0.37	GO:0030168	platelet activation
0.36	GO:0030334	regulation of cell migration
0.36	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

0.65	GO:0004872	receptor activity
0.37	GO:0005178	integrin binding
0.36	GO:0104005	hijacked molecular function
0.34	GO:0005080	protein kinase C binding
0.34	GO:0005509	calcium ion binding

0.81	GO:0008305	integrin complex
0.52	GO:0009986	cell surface
0.37	GO:0005925	focal adhesion
0.35	GO:0045335	phagocytic vesicle
0.35	GO:0031252	cell leading edge
0.35	GO:0070062	extracellular exosome
0.35	GO:0035866	alphav-beta3 integrin-PKCalpha complex
0.35	GO:0071133	alpha9-beta1 integrin-ADAM8 complex
0.34	GO:0016324	apical plasma membrane
0.33	GO:0098552	side of membrane

sp|O70310|NMT1_MOUSE
Glycylpeptide N-tetradecanoyltransferase 1
Search

NMT1

0.72	Glycylpeptide N-tetradecanoyltransferase

0.85	GO:0006499	N-terminal protein myristoylation
0.59	GO:0018201	peptidyl-glycine modification
0.51	GO:0001701	in utero embryonic development
0.48	GO:0042180	cellular ketone metabolic process
0.36	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
0.35	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
0.35	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.35	GO:1903749	positive regulation of establishment of protein localization to mitochondrion
0.34	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.34	GO:1905477	positive regulation of protein localization to membrane

0.85	GO:0004379	glycylpeptide N-tetradecanoyltransferase activity
0.35	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.34	GO:0017069	snRNA binding
0.34	GO:0000062	fatty-acyl-CoA binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0019898	extrinsic component of membrane
0.49	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.37	GO:0005794	Golgi apparatus
0.33	GO:0005739	mitochondrion
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.85

EC:2.3.1.97

GO:0004379

sp|O70311|NMT2_MOUSE
Glycylpeptide N-tetradecanoyltransferase 2
Search

NMT2

0.73	Glycylpeptide N-tetradecanoyltransferase

0.85	GO:0006499	N-terminal protein myristoylation
0.60	GO:0018201	peptidyl-glycine modification
0.35	GO:0001701	in utero embryonic development
0.35	GO:0042180	cellular ketone metabolic process
0.35	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.34	GO:0075733	intracellular transport of virus

0.85	GO:0004379	glycylpeptide N-tetradecanoyltransferase activity
0.36	GO:0000062	fatty-acyl-CoA binding

0.51	GO:0019898	extrinsic component of membrane
0.48	GO:0005794	Golgi apparatus
0.48	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.33	GO:0044216	other organism cell
0.33	GO:0018995	host
0.30	GO:0016021	integral component of membrane

0.85

EC:2.3.1.97

GO:0004379

sp|O70318|E41L2_MOUSE
Band 4.1-like protein 2
Search

EPB41L2

0.96	Erythrocyte membrane protein band 4.1 like 2

0.79	GO:0030866	cortical actin cytoskeleton organization
0.62	GO:1904778	positive regulation of protein localization to cell cortex
0.48	GO:0031032	actomyosin structure organization
0.36	GO:0051301	cell division
0.36	GO:0007049	cell cycle
0.35	GO:0008360	regulation of cell shape
0.32	GO:0098655	cation transmembrane transport

0.71	GO:0008092	cytoskeletal protein binding
0.60	GO:0042731	PH domain binding
0.60	GO:0005198	structural molecule activity
0.33	GO:0005261	cation channel activity

0.69	GO:0005856	cytoskeleton
0.57	GO:0099738	cell cortex region
0.56	GO:0008180	COP9 signalosome
0.53	GO:0030054	cell junction
0.50	GO:0005654	nucleoplasm
0.44	GO:0005886	plasma membrane
0.38	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|O70324|MOT8_MOUSE
Monocarboxylate transporter 8
Search

SLC16A2

0.97	Solute carrier family 16 (Monocarboxylic acid transporters), member 2

0.86	GO:0070327	thyroid hormone transport
0.55	GO:0055085	transmembrane transport
0.51	GO:0046942	carboxylic acid transport
0.41	GO:0071705	nitrogen compound transport
0.37	GO:0021529	spinal cord oligodendrocyte cell differentiation
0.37	GO:0030878	thyroid gland development
0.37	GO:0014037	Schwann cell differentiation
0.36	GO:0043009	chordate embryonic development
0.36	GO:0007420	brain development
0.36	GO:0030182	neuron differentiation

0.86	GO:0015349	thyroid hormone transmembrane transporter activity
0.52	GO:0046943	carboxylic acid transmembrane transporter activity
0.37	GO:0070324	thyroid hormone binding

0.67

GO:0005887

integral component of plasma membrane

sp|O70326|GREM1_MOUSE
Gremlin-1
Search

GREM1

0.97	Gremlin 1, DAN family BMP antagonist

0.74	GO:0010469	regulation of receptor activity
0.68	GO:0090291	negative regulation of osteoclast proliferation
0.68	GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis
0.68	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation
0.68	GO:0003257	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
0.67	GO:1900155	negative regulation of bone trabecula formation
0.67	GO:0060676	ureteric bud formation
0.67	GO:0048263	determination of dorsal identity
0.67	GO:1900158	negative regulation of bone mineralization involved in bone maturation
0.67	GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis

0.77	GO:0005125	cytokine activity
0.68	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.68	GO:0043184	vascular endothelial growth factor receptor 2 binding
0.66	GO:0036122	BMP binding
0.57	GO:0042803	protein homodimerization activity
0.40	GO:0016015	morphogen activity
0.39	GO:0008201	heparin binding
0.37	GO:0043395	heparan sulfate proteoglycan binding

0.72	GO:0005615	extracellular space
0.57	GO:0009986	cell surface
0.30	GO:0016020	membrane

sp|O70333|CRIPT_MOUSE
Cysteine-rich PDZ-binding protein
Search

CRIPT

0.94	CXXC repeat containing interactor of PDZ3 domain

0.78	GO:1902897	regulation of postsynaptic density protein 95 clustering
0.75	GO:0035372	protein localization to microtubule
0.70	GO:0031122	cytoplasmic microtubule organization
0.56	GO:0045184	establishment of protein localization
0.35	GO:0032259	methylation

0.82	GO:0030165	PDZ domain binding
0.80	GO:0097110	scaffold protein binding
0.64	GO:0032403	protein complex binding
0.63	GO:0008017	microtubule binding
0.35	GO:0008168	methyltransferase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0003676	nucleic acid binding

0.76	GO:0001650	fibrillar center
0.73	GO:0043198	dendritic shaft
0.71	GO:0043197	dendritic spine
0.70	GO:0014069	postsynaptic density
0.68	GO:0043025	neuronal cell body
0.45	GO:0030054	cell junction
0.39	GO:0005737	cytoplasm

0.35

GO:0008168

sp|O70337|BIK_MOUSE
Bcl-2-interacting killer
Search

BIK

0.97	Bcl-2-interacting killer

0.78	GO:0006915	apoptotic process
0.71	GO:0032464	positive regulation of protein homooligomerization
0.69	GO:0090200	positive regulation of release of cytochrome c from mitochondria
0.59	GO:0008584	male gonad development
0.54	GO:0007283	spermatogenesis
0.52	GO:0007005	mitochondrion organization

0.60	GO:0051400	BH domain binding
0.51	GO:0046982	protein heterodimerization activity

0.47	GO:0005740	mitochondrial envelope
0.45	GO:0012505	endomembrane system
0.43	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

sp|O70338|RNH1_MOUSE
Ribonuclease H1
Search

RNASEH1

0.89	Ribonuclease H1

0.70	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.49	GO:0043137	DNA replication, removal of RNA primer
0.39	GO:0006264	mitochondrial DNA replication
0.35	GO:0019509	L-methionine salvage from methylthioadenosine
0.32	GO:0055114	oxidation-reduction process

0.74	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.62	GO:0000287	magnesium ion binding
0.51	GO:0003676	nucleic acid binding
0.37	GO:0042803	protein homodimerization activity
0.35	GO:0010309	acireductone dioxygenase [iron(II)-requiring] activity
0.33	GO:0005506	iron ion binding

0.41	GO:0005634	nucleus
0.35	GO:0005739	mitochondrion
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.74	EC:3.1.26.4	GO:0004523
0.35	KEGG:R07364	GO:0010309

sp|O70340|NPTX2_MOUSE
Neuronal pentraxin-2
Search

NPTX2

0.97	Neuronal pentraxin IIb

0.75	GO:0008306	associative learning
0.53	GO:0050804	modulation of chemical synaptic transmission
0.51	GO:0042752	regulation of circadian rhythm
0.47	GO:0060385	axonogenesis involved in innervation
0.43	GO:0065008	regulation of biological quality
0.38	GO:0007268	chemical synaptic transmission

0.42	GO:0030246	carbohydrate binding
0.38	GO:0046872	metal ion binding

0.41	GO:0043160	acrosomal lumen
0.41	GO:0005576	extracellular region
0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|O70342|NPY5R_MOUSE
Neuropeptide Y receptor type 5
Search

NPY5R

0.97	Neuropeptide Y receptor type 5

0.80	GO:0007218	neuropeptide signaling pathway
0.67	GO:0003214	cardiac left ventricle morphogenesis
0.65	GO:0003151	outflow tract morphogenesis
0.61	GO:0007268	chemical synaptic transmission
0.55	GO:0007631	feeding behavior
0.52	GO:0008015	blood circulation
0.49	GO:0060112	generation of ovulation cycle rhythm
0.48	GO:0014050	negative regulation of glutamate secretion
0.48	GO:0032229	negative regulation of synaptic transmission, GABAergic
0.48	GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus

0.84	GO:0004983	neuropeptide Y receptor activity
0.33	GO:0016494	C-X-C chemokine receptor activity
0.33	GO:0050254	rhodopsin kinase activity

0.59	GO:0043005	neuron projection
0.38	GO:0005886	plasma membrane
0.35	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.33

EC:2.7.11.14

GO:0050254

sp|O70343|PRGC1_MOUSE
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
Search

PPARGC1A

0.95	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha

0.80	GO:0050873	brown fat cell differentiation
0.75	GO:0007005	mitochondrion organization
0.67	GO:2000507	positive regulation of energy homeostasis
0.67	GO:2001171	positive regulation of ATP biosynthetic process
0.66	GO:0014850	response to muscle activity
0.64	GO:0010822	positive regulation of mitochondrion organization
0.63	GO:0043524	negative regulation of neuron apoptotic process
0.62	GO:0051091	positive regulation of DNA binding transcription factor activity
0.60	GO:1901857	positive regulation of cellular respiration
0.58	GO:0002021	response to dietary excess

0.76	GO:0003712	transcription cofactor activity
0.73	GO:0008134	transcription factor binding
0.73	GO:0005102	receptor binding
0.62	GO:0031490	chromatin DNA binding
0.56	GO:0003723	RNA binding
0.55	GO:0031625	ubiquitin protein ligase binding
0.48	GO:0043565	sequence-specific DNA binding
0.47	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.41	GO:1990841	promoter-specific chromatin binding
0.41	GO:0043014	alpha-tubulin binding

0.51	GO:0005654	nucleoplasm
0.43	GO:1990844	interfibrillar mitochondrion
0.43	GO:1990843	subsarcolemmal mitochondrion
0.42	GO:0097440	apical dendrite
0.41	GO:0005719	nuclear euchromatin
0.40	GO:0043025	neuronal cell body
0.39	GO:0022626	cytosolic ribosome
0.35	GO:0055029	nuclear DNA-directed RNA polymerase complex

sp|O70348|DXO_MOUSE
Decapping and exoribonuclease protein
Search

DXO

0.97	Decapping exoribonuclease

0.53	GO:0050779	RNA destabilization
0.52	GO:0071028	nuclear mRNA surveillance
0.43	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.55	GO:0034353	RNA pyrophosphohydrolase activity
0.48	GO:0008409	5'-3' exonuclease activity
0.48	GO:0003729	mRNA binding
0.44	GO:0000287	magnesium ion binding
0.39	GO:1901265	nucleoside phosphate binding
0.38	GO:0036094	small molecule binding

0.67	GO:0005829	cytosol
0.61	GO:0005634	nucleus
0.55	GO:0005886	plasma membrane

sp|O70354|CAH11_MOUSE
Carbonic anhydrase-related protein 11
Search

CA11

0.94	Carbonic anhydrase XI

0.37	GO:0007420	brain development
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression
0.34	GO:0007623	circadian rhythm

0.51	GO:0004089	carbonate dehydratase activity
0.38	GO:0003700	DNA binding transcription factor activity
0.34	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding

0.76	GO:0016323	basolateral plasma membrane
0.47	GO:0005576	extracellular region
0.33	GO:0005634	nucleus

0.51

EC:4.2.1.1

GO:0004089

sp|O70355|BTNL2_MOUSE
Butyrophilin-like protein 2
Search

BTNL2

0.77	Butyrophilin-like protein 2

0.69	GO:1900042	positive regulation of interleukin-2 secretion
0.67	GO:0050860	negative regulation of T cell receptor signaling pathway
0.65	GO:0042102	positive regulation of T cell proliferation

0.56

GO:0005102

receptor binding

0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|O70361|PER3_MOUSE
Period circadian protein homolog 3
Search

PER3

0.86	Period circadian protein like protein 3

0.82	GO:0032922	circadian regulation of gene expression
0.61	GO:0045187	regulation of circadian sleep/wake cycle, sleep
0.57	GO:0050821	protein stabilization
0.56	GO:0000122	negative regulation of transcription by RNA polymerase II
0.47	GO:0009648	photoperiodism
0.39	GO:0009649	entrainment of circadian clock
0.39	GO:0045475	locomotor rhythm
0.39	GO:0042753	positive regulation of circadian rhythm
0.39	GO:0042542	response to hydrogen peroxide
0.39	GO:0016525	negative regulation of angiogenesis

0.56	GO:0031625	ubiquitin protein ligase binding
0.55	GO:0019900	kinase binding
0.38	GO:0003682	chromatin binding

0.47	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm

sp|O70362|PHLD_MOUSE
Phosphatidylinositol-glycan-specific phospholipase D
Search

GPLD1

0.97	Glycosylphosphatidylinositol-specific phospholipase D

0.71	GO:0071401	cellular response to triglyceride
0.70	GO:0006507	GPI anchor release
0.68	GO:0045919	positive regulation of cytolysis
0.68	GO:0071397	cellular response to cholesterol
0.67	GO:0002042	cell migration involved in sprouting angiogenesis
0.67	GO:0002430	complement receptor mediated signaling pathway
0.67	GO:0051044	positive regulation of membrane protein ectodomain proteolysis
0.65	GO:0071277	cellular response to calcium ion
0.65	GO:0008286	insulin receptor signaling pathway
0.64	GO:1900076	regulation of cellular response to insulin stimulus

0.87	GO:0004621	glycosylphosphatidylinositol phospholipase D activity
0.49	GO:0017080	sodium channel regulator activity
0.34	GO:0005515	protein binding

0.66	GO:0005576	extracellular region
0.46	GO:0043231	intracellular membrane-bounded organelle
0.42	GO:1990777	lipoprotein particle
0.42	GO:0005737	cytoplasm
0.37	GO:0031982	vesicle
0.37	GO:0098805	whole membrane
0.37	GO:0098588	bounding membrane of organelle
0.35	GO:0044446	intracellular organelle part

0.87

EC:3.1.4.50

GO:0004621

sp|O70370|CATS_MOUSE
Cathepsin S
Search

CTSS

0.89	LOW QUALITY PROTEIN: cathepsin S

0.61	GO:0034769	basement membrane disassembly
0.61	GO:0006508	proteolysis
0.58	GO:0030574	collagen catabolic process
0.58	GO:0097067	cellular response to thyroid hormone stimulus
0.57	GO:2001259	positive regulation of cation channel activity
0.56	GO:0010447	response to acidic pH
0.54	GO:0002250	adaptive immune response
0.54	GO:0048002	antigen processing and presentation of peptide antigen
0.51	GO:0044257	cellular protein catabolic process
0.50	GO:0051604	protein maturation

0.72	GO:0008234	cysteine-type peptidase activity
0.59	GO:0001968	fibronectin binding
0.57	GO:0043394	proteoglycan binding
0.57	GO:0043236	laminin binding
0.56	GO:0005518	collagen binding
0.48	GO:0004175	endopeptidase activity
0.35	GO:0042393	histone binding
0.35	GO:0097655	serpin family protein binding
0.35	GO:0017171	serine hydrolase activity
0.35	GO:0030984	kininogen binding

0.55	GO:0005764	lysosome
0.52	GO:0005615	extracellular space
0.38	GO:0031904	endosome lumen
0.36	GO:0030141	secretory granule
0.35	GO:0031981	nuclear lumen
0.35	GO:0005769	early endosome
0.35	GO:0009986	cell surface
0.35	GO:0005775	vacuolar lumen
0.34	GO:0043204	perikaryon
0.34	GO:0005902	microvillus

0.72

GO:0008234

sp|O70372|TERT_MOUSE
Telomerase reverse transcriptase
Search

TERT

0.75	Telomerase reverse transcriptase

0.69	GO:0006278	RNA-dependent DNA biosynthetic process
0.65	GO:0010833	telomere maintenance via telomere lengthening
0.65	GO:1903704	negative regulation of production of siRNA involved in RNA interference
0.63	GO:1904751	positive regulation of protein localization to nucleolus
0.63	GO:0070200	establishment of protein localization to telomere
0.62	GO:2000773	negative regulation of cellular senescence
0.62	GO:0051000	positive regulation of nitric-oxide synthase activity
0.61	GO:0090399	replicative senescence
0.61	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II
0.61	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

0.85	GO:0003721	telomerase RNA reverse transcriptase activity
0.65	GO:0098680	template-free RNA nucleotidyltransferase
0.65	GO:0070034	telomerase RNA binding
0.62	GO:0001223	transcription coactivator binding
0.59	GO:0047485	protein N-terminus binding
0.58	GO:0008022	protein C-terminus binding
0.55	GO:0051087	chaperone binding
0.55	GO:0003677	DNA binding
0.54	GO:0042803	protein homodimerization activity
0.52	GO:0003968	RNA-directed 5'-3' RNA polymerase activity

0.67	GO:0000333	telomerase catalytic core complex
0.65	GO:1990572	TERT-RMRP complex
0.60	GO:0016605	PML body
0.58	GO:0042645	mitochondrial nucleoid
0.58	GO:0000781	chromosome, telomeric region
0.56	GO:0016607	nuclear speck
0.54	GO:0005730	nucleolus
0.53	GO:0044454	nuclear chromosome part
0.50	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane

0.52

EC:2.7.7.48

GO:0003968

sp|O70373|XIRP1_MOUSE
Xin actin-binding repeat-containing protein 1
Search

0.10	Xin actin-binding repeat-containing protein 1

0.79	GO:0007507	heart development
0.73	GO:0030036	actin cytoskeleton organization
0.45	GO:0032091	negative regulation of protein binding
0.44	GO:0060415	muscle tissue morphogenesis
0.43	GO:0045216	cell-cell junction organization
0.43	GO:0014706	striated muscle tissue development
0.30	GO:0048519	negative regulation of biological process
0.30	GO:0097435	supramolecular fiber organization
0.30	GO:0032989	cellular component morphogenesis
0.30	GO:0007165	signal transduction

0.73	GO:0003779	actin binding
0.44	GO:0051393	alpha-actinin binding
0.35	GO:0046872	metal ion binding
0.33	GO:0003723	RNA binding
0.30	GO:0031005	filamin binding

0.74	GO:0030054	cell junction
0.52	GO:0031941	filamentous actin
0.52	GO:0097517	contractile actin filament bundle
0.51	GO:0042641	actomyosin
0.43	GO:0030018	Z disc

sp|O70374|MTG8R_MOUSE
Protein CBFA2T2
Search

CBFA2T2

0.97	Core-binding factor, runt domain, alpha subunit 2 translocated to, 2

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.54	GO:0060575	intestinal epithelial cell differentiation
0.53	GO:0045746	negative regulation of Notch signaling pathway
0.53	GO:0010976	positive regulation of neuron projection development
0.46	GO:0006357	regulation of transcription by RNA polymerase II
0.38	GO:0010977	negative regulation of neuron projection development
0.34	GO:0006351	transcription, DNA-templated

0.81	GO:0003714	transcription corepressor activity
0.61	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding
0.31	GO:0003677	DNA binding

0.45

GO:0005634

nucleus

sp|O70378|EMC8_MOUSE
ER membrane protein complex subunit 8
Search

EMC8

0.93	ER membrane protein complex subunit 8

0.36

GO:0005515

protein binding

0.84	GO:0072546	ER membrane protein complex
0.66	GO:0005829	cytosol
0.59	GO:0005739	mitochondrion
0.36	GO:0005634	nucleus

sp|O70394|I27RA_MOUSE
Interleukin-27 receptor subunit alpha
Search

IL27RA

0.97	Interleukin-27 receptor subunit alpha

0.76	GO:0070106	interleukin-27-mediated signaling pathway
0.73	GO:0048302	regulation of isotype switching to IgG isotypes
0.73	GO:0002829	negative regulation of type 2 immune response
0.73	GO:0002827	positive regulation of T-helper 1 type immune response
0.70	GO:0032729	positive regulation of interferon-gamma production
0.69	GO:0050830	defense response to Gram-positive bacterium
0.42	GO:0070757	interleukin-35-mediated signaling pathway
0.38	GO:0010469	regulation of receptor activity
0.38	GO:0006955	immune response

0.78	GO:0045509	interleukin-27 receptor activity
0.40	GO:0005515	protein binding
0.38	GO:0030545	receptor regulator activity

0.41	GO:0005576	extracellular region
0.38	GO:0005886	plasma membrane
0.35	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|O70400|PDLI1_MOUSE
PDZ and LIM domain protein 1
Search

PDLIM1

0.93	PDZ and LIM domain protein 1

0.53	GO:0098609	cell-cell adhesion
0.43	GO:2001141	regulation of RNA biosynthetic process
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.40	GO:0001666	response to hypoxia
0.37	GO:0031532	actin cytoskeleton reorganization
0.35	GO:0098976	excitatory chemical synaptic transmission
0.34	GO:0006979	response to oxidative stress
0.34	GO:0060173	limb development

0.59	GO:0098641	cadherin binding involved in cell-cell adhesion
0.54	GO:0003713	transcription coactivator activity
0.53	GO:0046872	metal ion binding
0.39	GO:0051393	alpha-actinin binding
0.38	GO:0019903	protein phosphatase binding
0.37	GO:0042803	protein homodimerization activity
0.34	GO:0051015	actin filament binding

0.67	GO:0005856	cytoskeleton
0.56	GO:0005913	cell-cell adherens junction
0.52	GO:0005667	transcription factor complex
0.40	GO:0030018	Z disc
0.38	GO:0030027	lamellipodium
0.37	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005925	focal adhesion
0.35	GO:0034777	recycling endosome lumen
0.35	GO:0005634	nucleus
0.35	GO:0031905	early endosome lumen

sp|O70401|TSN6_MOUSE
Tetraspanin-6
Search

TSPAN6

0.57	Tetraspanin

0.58	GO:1901223	negative regulation of NIK/NF-kappaB signaling
0.58	GO:0039532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway
0.46	GO:0007166	cell surface receptor signaling pathway
0.38	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.33	GO:0016032	viral process

0.35	GO:0004871	signal transducer activity
0.33	GO:0005515	protein binding

0.44	GO:0005887	integral component of plasma membrane
0.37	GO:0070062	extracellular exosome

sp|O70404|VAMP8_MOUSE
Vesicle-associated membrane protein 8
Search

VAMP8

0.97	Vesicle-associated membrane protein 8

0.69	GO:0016192	vesicle-mediated transport
0.63	GO:0070254	mucus secretion
0.63	GO:1903595	positive regulation of histamine secretion by mast cell
0.63	GO:0016240	autophagosome membrane docking
0.58	GO:1903076	regulation of protein localization to plasma membrane
0.58	GO:1903531	negative regulation of secretion by cell
0.50	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.50	GO:0044409	entry into host
0.50	GO:0090174	organelle membrane fusion
0.49	GO:0065009	regulation of molecular function

0.62	GO:0019869	chloride channel inhibitor activity
0.49	GO:0000149	SNARE binding
0.49	GO:0005484	SNAP receptor activity

0.64	GO:0098594	mucin granule
0.62	GO:0035577	azurophil granule membrane
0.60	GO:0031201	SNARE complex
0.58	GO:0031902	late endosome membrane
0.57	GO:0055037	recycling endosome
0.55	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005829	cytosol
0.48	GO:0008021	synaptic vesicle
0.44	GO:0005886	plasma membrane
0.43	GO:0031901	early endosome membrane

sp|O70405|ULK1_MOUSE
Serine/threonine-protein kinase ULK1
Search

ULK1

0.97	Unc-51 like autophagy activating kinase 1

0.73	GO:0075044	autophagy of host cells involved in interaction with symbiont
0.67	GO:0031175	neuron projection development
0.66	GO:0018107	peptidyl-threonine phosphorylation
0.65	GO:0046777	protein autophosphorylation
0.65	GO:0018105	peptidyl-serine phosphorylation
0.64	GO:0016236	macroautophagy
0.64	GO:0031333	negative regulation of protein complex assembly
0.59	GO:0048667	cell morphogenesis involved in neuron differentiation
0.59	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.55	GO:0048588	developmental cell growth

0.70	GO:0004674	protein serine/threonine kinase activity
0.64	GO:0017137	Rab GTPase binding
0.60	GO:0032403	protein complex binding
0.59	GO:0042802	identical protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0097635	extrinsic component of autophagosome membrane
0.72	GO:0097629	extrinsic component of omegasome membrane
0.71	GO:0097632	extrinsic component of phagophore assembly site membrane
0.70	GO:1990316	Atg1/ULK1 kinase complex
0.68	GO:0032045	guanyl-nucleotide exchange factor complex
0.56	GO:0005829	cytosol

0.70

GO:0004674

sp|O70410|V2R1_MOUSE
Vomeronasal type-2 receptor 1
Search

VN2R1

0.95	Extracellular calcium-sensing receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.41	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.37	GO:0001501	skeletal system development
0.37	GO:0055074	calcium ion homeostasis
0.36	GO:0019236	response to pheromone
0.34	GO:0006177	GMP biosynthetic process

0.72	GO:0004930	G-protein coupled receptor activity
0.41	GO:0004984	olfactory receptor activity
0.35	GO:0003922	GMP synthase (glutamine-hydrolyzing) activity
0.33	GO:0016462	pyrophosphatase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0005886	plasma membrane
0.38	GO:0030425	dendrite
0.35	GO:0005938	cell cortex
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:6.3.5.2

GO:0003922

sp|O70421|FZD1_MOUSE
Frizzled-1
Search

FZD1

0.90	Frizzled class receptor 1

0.77	GO:0016055	Wnt signaling pathway
0.69	GO:0007275	multicellular organism development
0.61	GO:0060022	hard palate development
0.60	GO:0090178	regulation of establishment of planar polarity involved in neural tube closure
0.58	GO:0060429	epithelium development
0.57	GO:0048729	tissue morphogenesis
0.56	GO:0051091	positive regulation of DNA binding transcription factor activity
0.56	GO:0035412	regulation of catenin import into nucleus
0.56	GO:0035425	autocrine signaling
0.55	GO:0072497	mesenchymal stem cell differentiation

0.85	GO:0042813	Wnt-activated receptor activity
0.60	GO:0030165	PDZ domain binding
0.60	GO:0017147	Wnt-protein binding
0.56	GO:0005109	frizzled binding
0.47	GO:0004930	G-protein coupled receptor activity
0.42	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.35	GO:0046982	protein heterodimerization activity
0.35	GO:0042802	identical protein binding
0.35	GO:0045545	syndecan binding

0.48	GO:0009986	cell surface
0.42	GO:0055038	recycling endosome membrane
0.42	GO:0005886	plasma membrane
0.38	GO:0005925	focal adhesion
0.36	GO:1990909	Wnt signalosome
0.34	GO:0043005	neuron projection
0.34	GO:0030669	clathrin-coated endocytic vesicle membrane
0.30	GO:0016021	integral component of membrane

sp|O70422|TF2H4_MOUSE
General transcription factor IIH subunit 4
Search

GTF2H4

0.84	General transcription factor IIH subunit 4

0.73	GO:0006289	nucleotide-excision repair
0.70	GO:0032392	DNA geometric change
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0006468	protein phosphorylation
0.42	GO:0010224	response to UV-B
0.41	GO:0032781	positive regulation of ATPase activity
0.36	GO:0071824	protein-DNA complex subunit organization

0.72	GO:0004003	ATP-dependent DNA helicase activity
0.61	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.47	GO:0003690	double-stranded DNA binding
0.43	GO:0140110	transcription regulator activity
0.41	GO:0001671	ATPase activator activity
0.33	GO:0005515	protein binding

0.81	GO:0000439	core TFIIH complex
0.61	GO:0005675	holo TFIIH complex
0.55	GO:0016607	nuclear speck
0.55	GO:0005669	transcription factor TFIID complex
0.30	GO:0016020	membrane

0.61

EC:2.7.11.23

GO:0008353

sp|O70423|AOC3_MOUSE
Membrane primary amine oxidase
Search

0.49	Retina-specific copper amine oxidase

0.70	GO:0009308	amine metabolic process
0.61	GO:0007601	visual perception
0.53	GO:0055114	oxidation-reduction process
0.52	GO:1902283	negative regulation of primary amine oxidase activity
0.45	GO:0007155	cell adhesion
0.45	GO:0046677	response to antibiotic
0.37	GO:0006954	inflammatory response
0.36	GO:0006584	catecholamine metabolic process
0.36	GO:0035902	response to immobilization stress
0.36	GO:0002675	positive regulation of acute inflammatory response

0.83	GO:0008131	primary amine oxidase activity
0.72	GO:0048038	quinone binding
0.72	GO:0005507	copper ion binding
0.47	GO:0052593	tryptamine:oxygen oxidoreductase (deaminating) activity
0.47	GO:0052596	phenethylamine:oxygen oxidoreductase (deaminating) activity
0.47	GO:0052594	aminoacetone:oxygen oxidoreductase(deaminating) activity
0.47	GO:0052595	aliphatic-amine oxidase activity
0.45	GO:0046982	protein heterodimerization activity
0.44	GO:0005509	calcium ion binding
0.36	GO:0042803	protein homodimerization activity

0.49	GO:0005902	microvillus
0.47	GO:0005769	early endosome
0.47	GO:0009986	cell surface
0.44	GO:0005794	Golgi apparatus
0.44	GO:0005783	endoplasmic reticulum
0.40	GO:0005886	plasma membrane
0.37	GO:0005615	extracellular space
0.36	GO:0008537	proteasome activator complex
0.30	GO:0016021	integral component of membrane

0.83	EC:1.4.3.21	GO:0008131
0.83	KEGG:R01853	GO:0008131

sp|O70433|FHL2_MOUSE
Four and a half LIM domains protein 2
Search

FHL2

0.94	Four and a half LIM domains protein 2

0.55	GO:0055014	atrial cardiac muscle cell development
0.54	GO:0055015	ventricular cardiac muscle cell development
0.54	GO:0060347	heart trabecula formation
0.52	GO:0001649	osteoblast differentiation
0.49	GO:0043066	negative regulation of apoptotic process
0.49	GO:0000122	negative regulation of transcription by RNA polymerase II
0.47	GO:0009725	response to hormone
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0030522	intracellular receptor signaling pathway
0.34	GO:0019216	regulation of lipid metabolic process

0.54	GO:0046872	metal ion binding
0.47	GO:0042802	identical protein binding
0.47	GO:0008134	transcription factor binding
0.34	GO:0051427	hormone receptor binding
0.34	GO:0003713	transcription coactivator activity
0.33	GO:0004707	MAP kinase activity
0.33	GO:0003779	actin binding
0.32	GO:0005524	ATP binding

0.42	GO:0005634	nucleus
0.40	GO:0031430	M band
0.39	GO:0030018	Z disc
0.36	GO:0005925	focal adhesion
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part

0.33	EC:2.7.11.24	GO:0004707
0.33	KEGG:R00162	GO:0004707

sp|O70435|PSA3_MOUSE
Proteasome subunit alpha type-3
Search

PSMA3

0.49	Proteasome endopeptidase complex

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.71	GO:0043632	modification-dependent macromolecule catabolic process
0.49	GO:0052548	regulation of endopeptidase activity
0.36	GO:0007224	smoothened signaling pathway
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation

0.77	GO:0070003	threonine-type peptidase activity
0.64	GO:0004175	endopeptidase activity
0.34	GO:0005515	protein binding
0.34	GO:0003677	DNA binding

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.60	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.38	GO:0045202	synapse
0.36	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

sp|O70439|STX7_MOUSE
Syntaxin-7
Search

STX7

0.93	Syntaxin 7 (Predicted)

0.69	GO:0016192	vesicle-mediated transport
0.68	GO:0006886	intracellular protein transport
0.68	GO:0061025	membrane fusion
0.61	GO:1902685	positive regulation of receptor localization to synapse
0.59	GO:0001916	positive regulation of T cell mediated cytotoxicity
0.57	GO:1903076	regulation of protein localization to plasma membrane
0.54	GO:0051640	organelle localization
0.51	GO:0070925	organelle assembly
0.48	GO:0065009	regulation of molecular function
0.47	GO:0048284	organelle fusion

0.80	GO:0005484	SNAP receptor activity
0.60	GO:0019869	chloride channel inhibitor activity
0.57	GO:0000149	SNARE binding
0.34	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.34	GO:0032403	protein complex binding
0.34	GO:0005507	copper ion binding

0.59	GO:0070820	tertiary granule
0.59	GO:0005766	primary lysosome
0.58	GO:0001772	immunological synapse
0.56	GO:0055037	recycling endosome
0.56	GO:0030139	endocytic vesicle
0.55	GO:0005769	early endosome
0.55	GO:0005770	late endosome
0.54	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0031201	SNARE complex
0.39	GO:0098805	whole membrane

0.34

EC:1.14.17

GO:0016715

sp|O70443|GNAZ_MOUSE
Guanine nucleotide-binding protein G(z) subunit alpha
Search

GNAZ

0.97	G protein subunit alpha z

0.74	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.34	GO:0006457	protein folding
0.32	GO:0055085	transmembrane transport

0.76	GO:0031683	G-protein beta/gamma-subunit complex binding
0.64	GO:0003924	GTPase activity
0.62	GO:0032550	purine ribonucleoside binding
0.62	GO:0019001	guanyl nucleotide binding
0.61	GO:0004871	signal transducer activity
0.52	GO:0032555	purine ribonucleotide binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0001664	G-protein coupled receptor binding
0.34	GO:0046872	metal ion binding
0.32	GO:0022857	transmembrane transporter activity

0.50	GO:0030425	dendrite
0.50	GO:0044297	cell body
0.46	GO:1905360	GTPase complex
0.45	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.41	GO:0098797	plasma membrane protein complex
0.37	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.34	GO:0005635	nuclear envelope
0.34	GO:0005783	endoplasmic reticulum

sp|O70445|BARD1_MOUSE
BRCA1-associated RING domain protein 1
Search

BARD1

0.94	BRCA1-associated RING domain protein 1

0.77	GO:0043065	positive regulation of apoptotic process
0.71	GO:0016567	protein ubiquitination
0.64	GO:0046826	negative regulation of protein export from nucleus
0.57	GO:0043066	negative regulation of apoptotic process
0.54	GO:0042325	regulation of phosphorylation
0.37	GO:0006974	cellular response to DNA damage stimulus
0.37	GO:0000732	strand displacement
0.36	GO:0031441	negative regulation of mRNA 3'-end processing
0.36	GO:0032501	multicellular organismal process
0.36	GO:1901796	regulation of signal transduction by p53 class mediator

0.55	GO:0042803	protein homodimerization activity
0.54	GO:0046982	protein heterodimerization activity
0.54	GO:0004842	ubiquitin-protein transferase activity
0.46	GO:0003723	RNA binding
0.35	GO:0019900	kinase binding
0.35	GO:0046872	metal ion binding
0.34	GO:0016874	ligase activity
0.34	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0043168	anion binding

0.85	GO:0031436	BRCA1-BARD1 complex
0.61	GO:0070531	BRCA1-A complex
0.58	GO:0016607	nuclear speck
0.57	GO:0036464	cytoplasmic ribonucleoprotein granule
0.32	GO:0042405	nuclear inclusion body
0.32	GO:0035861	site of double-strand break
0.32	GO:0005813	centrosome
0.32	GO:0000786	nucleosome
0.30	GO:0016020	membrane

0.34	EC:6	GO:0016874
0.54	KEGG:R03876	GO:0004842

sp|O70451|MOT2_MOUSE
Monocarboxylate transporter 2
Search

SLC16A7

0.81	Solute carrier family 16, member 7 (Monocarboxylic acid transporter 2)

0.81	GO:1901475	pyruvate transmembrane transport
0.69	GO:0035873	lactate transmembrane transport
0.44	GO:0051780	behavioral response to nutrient
0.44	GO:0032094	response to food
0.42	GO:0050796	regulation of insulin secretion
0.42	GO:0007098	centrosome cycle
0.42	GO:0042593	glucose homeostasis
0.38	GO:0006629	lipid metabolic process
0.36	GO:0071407	cellular response to organic cyclic compound

0.76	GO:0008028	monocarboxylic acid transmembrane transporter activity
0.67	GO:1901618	organic hydroxy compound transmembrane transporter activity
0.36	GO:0042803	protein homodimerization activity
0.32	GO:0097159	organic cyclic compound binding

0.67	GO:0005887	integral component of plasma membrane
0.41	GO:0005813	centrosome
0.40	GO:0030054	cell junction
0.37	GO:0005739	mitochondrion

sp|O70456|1433S_MOUSE
14-3-3 protein sigma
Search

SFN

0.94	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like

0.59	GO:0010482	regulation of epidermal cell division
0.58	GO:0001836	release of cytochrome c from mitochondria
0.58	GO:0010839	negative regulation of keratinocyte proliferation
0.58	GO:0045606	positive regulation of epidermal cell differentiation
0.57	GO:0003334	keratinocyte development
0.57	GO:0061436	establishment of skin barrier
0.57	GO:0031424	keratinization
0.56	GO:0046827	positive regulation of protein export from nucleus
0.56	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.56	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

0.77	GO:0019904	protein domain specific binding
0.55	GO:0051219	phosphoprotein binding
0.54	GO:0045296	cadherin binding
0.52	GO:0019901	protein kinase binding
0.51	GO:0042802	identical protein binding
0.36	GO:0008426	protein kinase C inhibitor activity
0.35	GO:0004497	monooxygenase activity
0.34	GO:0004584	dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity
0.34	GO:0047485	protein N-terminus binding
0.34	GO:0019706	protein-cysteine S-palmitoyltransferase activity

0.48	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.37	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.34	GO:0031090	organelle membrane
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005739	mitochondrion
0.33	GO:0032991	macromolecular complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.34

EC:2.4.1.130

GO:0004584

sp|O70458|OSMR_MOUSE
Oncostatin-M-specific receptor subunit beta
Search

OSMR

0.90	Oncostatin M receptor

0.84	GO:0038165	oncostatin-M-mediated signaling pathway
0.72	GO:0008284	positive regulation of cell proliferation

0.85	GO:0004924	oncostatin-M receptor activity
0.75	GO:0019838	growth factor binding

0.85	GO:0005900	oncostatin-M receptor complex
0.75	GO:0016324	apical plasma membrane

sp|O70460|CCL19_MOUSE
C-C motif chemokine 19
Search

CCL19

0.70	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.74	GO:0010469	regulation of receptor activity
0.73	GO:2000669	negative regulation of dendritic cell apoptotic process
0.73	GO:0001768	establishment of T cell polarity
0.72	GO:0071731	response to nitric oxide
0.71	GO:0034695	response to prostaglandin E
0.71	GO:0036336	dendritic cell migration
0.71	GO:0042346	positive regulation of NF-kappaB import into nucleus
0.71	GO:0090023	positive regulation of neutrophil chemotaxis

0.84	GO:0008009	chemokine activity
0.75	GO:0031735	CCR10 chemokine receptor binding
0.48	GO:0031732	CCR7 chemokine receptor binding

0.72	GO:0005615	extracellular space
0.41	GO:0009897	external side of plasma membrane
0.34	GO:0005622	intracellular

sp|O70468|MYPC3_MOUSE
Myosin-binding protein C, cardiac-type
Search

MYBPC3

0.92	Mutant cardiac myosin-binding protein C

0.85	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.63	GO:0071688	striated muscle myosin thick filament assembly
0.60	GO:0045214	sarcomere organization
0.60	GO:0006941	striated muscle contraction
0.56	GO:0003210	cardiac atrium formation
0.54	GO:0007015	actin filament organization
0.54	GO:0003211	cardiac ventricle formation
0.51	GO:0002027	regulation of heart rate

0.85	GO:0032036	myosin heavy chain binding
0.83	GO:0008307	structural constituent of muscle
0.69	GO:0042802	identical protein binding
0.63	GO:0097493	structural molecule activity conferring elasticity
0.63	GO:0051371	muscle alpha-actinin binding
0.56	GO:0051015	actin filament binding

0.85	GO:0005863	striated muscle myosin thick filament
0.85	GO:0097512	cardiac myofibril
0.82	GO:0031672	A band
0.59	GO:0030018	Z disc

sp|O70469|DOK2_MOUSE
Docking protein 2
Search

DOK2

0.91	Downstream of tyrosine kinase 2

0.80	GO:0007265	Ras protein signal transduction
0.75	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.41	GO:0000165	MAPK cascade
0.40	GO:0007411	axon guidance
0.39	GO:0050900	leukocyte migration
0.35	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway

0.82	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity
0.76	GO:0005057	signal transducer activity, downstream of receptor
0.38	GO:0016301	kinase activity

0.49	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.35	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|O70472|TM131_MOUSE
Transmembrane protein 131
Search

TMEM131

0.96	LOW QUALITY PROTEIN: transmembrane protein 131

0.30

GO:0044425

membrane part

sp|O70475|UGDH_MOUSE
UDP-glucose 6-dehydrogenase
Search

UGDH

0.45	UDP-glucose 6-dehydrogenase

0.56	GO:0001702	gastrulation with mouth forming second
0.53	GO:0055114	oxidation-reduction process
0.47	GO:0003190	atrioventricular valve formation
0.46	GO:0045880	positive regulation of smoothened signaling pathway
0.45	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.45	GO:0007368	determination of left/right symmetry
0.45	GO:0006024	glycosaminoglycan biosynthetic process
0.43	GO:0006065	UDP-glucuronate biosynthetic process
0.35	GO:0000271	polysaccharide biosynthetic process
0.34	GO:0007509	mesoderm migration involved in gastrulation

0.77	GO:0003979	UDP-glucose 6-dehydrogenase activity
0.68	GO:0051287	NAD binding
0.33	GO:0009055	electron transfer activity

0.48	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.77	EC:1.1.1.22	GO:0003979
0.77	KEGG:R00286	GO:0003979

sp|O70477|PKNX1_MOUSE
Homeobox protein PKNOX1
Search

PKNOX1

0.97	Homeobox-containing protein PKNOX1

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0030218	erythrocyte differentiation
0.55	GO:0030217	T cell differentiation
0.54	GO:0001525	angiogenesis
0.54	GO:0043010	camera-type eye development
0.51	GO:0006366	transcription by RNA polymerase II
0.50	GO:0051254	positive regulation of RNA metabolic process
0.49	GO:0010557	positive regulation of macromolecule biosynthetic process

0.55	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.55	GO:0003677	DNA binding
0.53	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.50	GO:0046982	protein heterodimerization activity
0.40	GO:0003785	actin monomer binding
0.39	GO:0051015	actin filament binding
0.39	GO:0001067	regulatory region nucleic acid binding

0.61	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.40	GO:0005737	cytoplasm
0.39	GO:0045171	intercellular bridge
0.38	GO:0015629	actin cytoskeleton
0.38	GO:0015630	microtubule cytoskeleton
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.34	GO:0045271	respiratory chain complex I
0.33	GO:1990204	oxidoreductase complex

sp|O70479|BACD2_MOUSE
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
Search

TNFAIP1

0.97	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

0.74	GO:0051260	protein homooligomerization
0.49	GO:0043149	stress fiber assembly
0.48	GO:0035024	negative regulation of Rho protein signal transduction
0.46	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.45	GO:0016477	cell migration
0.44	GO:0016567	protein ubiquitination
0.44	GO:0006955	immune response
0.39	GO:0045740	positive regulation of DNA replication
0.39	GO:0006260	DNA replication
0.37	GO:0045746	negative regulation of Notch signaling pathway

0.48	GO:0017049	GTP-Rho binding
0.44	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0019904	protein domain specific binding
0.37	GO:0005112	Notch binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0031463	Cul3-RING ubiquitin ligase complex
0.44	GO:0005768	endosome
0.42	GO:0005730	nucleolus
0.37	GO:0036038	MKS complex
0.35	GO:0005654	nucleoplasm
0.35	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.44

GO:0004842

sp|O70480|VAMP4_MOUSE
Vesicle-associated membrane protein 4
Search

VAMP4

0.95	Vesicle-associated membrane protein 4

0.69	GO:0016192	vesicle-mediated transport
0.57	GO:0090161	Golgi ribbon formation
0.55	GO:0090174	organelle membrane fusion
0.53	GO:0016050	vesicle organization
0.50	GO:0000226	microtubule cytoskeleton organization
0.48	GO:0043623	cellular protein complex assembly
0.42	GO:0032940	secretion by cell
0.40	GO:0061951	establishment of protein localization to plasma membrane
0.39	GO:0042996	regulation of Golgi to plasma membrane protein transport
0.38	GO:0071346	cellular response to interferon-gamma

0.46	GO:0000149	SNARE binding
0.45	GO:0005484	SNAP receptor activity

0.50	GO:0009986	cell surface
0.48	GO:0005794	Golgi apparatus
0.47	GO:0031201	SNARE complex
0.46	GO:0008021	synaptic vesicle
0.39	GO:0099501	exocytic vesicle membrane
0.38	GO:0045335	phagocytic vesicle
0.38	GO:0031301	integral component of organelle membrane
0.37	GO:0031984	organelle subcompartment
0.35	GO:0030665	clathrin-coated vesicle membrane
0.34	GO:0005764	lysosome

sp|O70481|UBR1_MOUSE
E3 ubiquitin-protein ligase UBR1
Search

UBR1

0.89	Ubiquitin protein ligase E3 component n-recognin 1

0.68	GO:0030163	protein catabolic process
0.61	GO:0071233	cellular response to leucine
0.58	GO:0032007	negative regulation of TOR signaling
0.53	GO:0016567	protein ubiquitination
0.52	GO:0043632	modification-dependent macromolecule catabolic process
0.46	GO:0006508	proteolysis

0.62	GO:0070728	leucine binding
0.60	GO:0008270	zinc ion binding
0.53	GO:0004842	ubiquitin-protein transferase activity
0.53	GO:0016874	ligase activity
0.43	GO:0061659	ubiquitin-like protein ligase activity
0.35	GO:0005515	protein binding

0.54	GO:0000151	ubiquitin ligase complex
0.52	GO:1905369	endopeptidase complex
0.45	GO:0043234	protein complex
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.53	EC:6	GO:0016874
0.53	KEGG:R03876	GO:0004842

sp|O70491|STRA6_MOUSE
Stimulated by retinoic acid gene 6 protein
Search

STRA6

0.97	stimulated by retinoic acid gene 6 protein homolog

0.79	GO:0035461	vitamin transmembrane transport
0.61	GO:0061143	alveolar primary septum development
0.61	GO:0043585	nose morphogenesis
0.60	GO:0061205	paramesonephric duct development
0.59	GO:0034633	retinol transport
0.59	GO:0097070	ductus arteriosus closure
0.59	GO:0098596	imitative learning
0.59	GO:0061038	uterus morphogenesis
0.59	GO:0060426	lung vasculature development
0.59	GO:0061156	pulmonary artery morphogenesis

0.74	GO:0090482	vitamin transmembrane transporter activity
0.63	GO:0004872	receptor activity
0.56	GO:0015665	alcohol transmembrane transporter activity
0.52	GO:0005319	lipid transporter activity
0.38	GO:0005516	calmodulin binding
0.38	GO:0042803	protein homodimerization activity
0.30	GO:0043178	alcohol binding
0.30	GO:0008289	lipid binding
0.30	GO:0019842	vitamin binding

0.47	GO:0005887	integral component of plasma membrane
0.44	GO:0043234	protein complex

sp|O70492|SNX3_MOUSE
Sorting nexin-3
Search

SNX3

0.75	Sorting nexin-3

0.61	GO:2000642	negative regulation of early endosome to late endosome transport
0.58	GO:0022615	protein to membrane docking
0.57	GO:0046597	negative regulation of viral entry into host cell
0.57	GO:0050765	negative regulation of phagocytosis
0.56	GO:0070676	intralumenal vesicle formation
0.56	GO:0042177	negative regulation of protein catabolic process
0.55	GO:0051224	negative regulation of protein transport
0.55	GO:0010324	membrane invagination
0.53	GO:0030111	regulation of Wnt signaling pathway
0.51	GO:0009617	response to bacterium

0.76	GO:0035091	phosphatidylinositol binding
0.54	GO:0019903	protein phosphatase binding

0.57	GO:0032009	early phagosome
0.54	GO:0031901	early endosome membrane
0.53	GO:0030904	retromer complex
0.52	GO:0030136	clathrin-coated vesicle
0.47	GO:0005829	cytosol
0.47	GO:0019898	extrinsic component of membrane
0.38	GO:0070062	extracellular exosome

sp|O70493|SNX12_MOUSE
Sorting nexin-12
Search

SNX12

0.96	Sorting nexin-12

0.57	GO:2000642	negative regulation of early endosome to late endosome transport
0.53	GO:0010955	negative regulation of protein processing
0.53	GO:0042177	negative regulation of protein catabolic process
0.52	GO:0051224	negative regulation of protein transport
0.52	GO:0030100	regulation of endocytosis
0.45	GO:0016050	vesicle organization
0.42	GO:0006897	endocytosis
0.35	GO:0022615	protein to membrane docking
0.35	GO:0042541	hemoglobin biosynthetic process
0.35	GO:0046597	negative regulation of viral entry into host cell

0.75	GO:0035091	phosphatidylinositol binding
0.47	GO:0019899	enzyme binding

0.51	GO:0005769	early endosome
0.44	GO:0019898	extrinsic component of membrane
0.38	GO:0070062	extracellular exosome
0.35	GO:0032009	early phagosome
0.34	GO:0030904	retromer complex
0.34	GO:0030136	clathrin-coated vesicle
0.34	GO:0010008	endosome membrane
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|O70494|SP3_MOUSE
Transcription factor Sp3
Search

SP3

0.96	Transcription factor Sp3

0.59	GO:0043353	enucleate erythrocyte differentiation
0.59	GO:0001779	natural killer cell differentiation
0.58	GO:1903131	mononuclear cell differentiation
0.58	GO:0030219	megakaryocyte differentiation
0.58	GO:0030851	granulocyte differentiation
0.57	GO:0060216	definitive hemopoiesis
0.57	GO:0048596	embryonic camera-type eye morphogenesis
0.56	GO:0060136	embryonic process involved in female pregnancy
0.56	GO:0030183	B cell differentiation
0.56	GO:0001889	liver development

0.76	GO:0000987	proximal promoter sequence-specific DNA binding
0.59	GO:0003700	DNA binding transcription factor activity
0.54	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.52	GO:0003682	chromatin binding
0.36	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding

0.59	GO:0005634	nucleus
0.54	GO:0017053	transcriptional repressor complex
0.37	GO:0032993	protein-DNA complex
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|O70496|CLCN7_MOUSE
H(+)/Cl(-) exchange transporter 7
Search

CLCN7

0.51	Chloride voltage-gated channel 7

0.76	GO:1902476	chloride transmembrane transport
0.35	GO:0009268	response to pH

0.77

GO:0005247

voltage-gated chloride channel activity

0.47	GO:0005654	nucleoplasm
0.34	GO:0031410	cytoplasmic vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|O70497|FCN2_MOUSE
Ficolin-2
Search

FCN2

0.88

Ficolin B

0.73	GO:0043654	recognition of apoptotic cell
0.72	GO:0001867	complement activation, lectin pathway
0.69	GO:0002752	cell surface pattern recognition receptor signaling pathway
0.66	GO:2000484	positive regulation of interleukin-8 secretion
0.65	GO:0046597	negative regulation of viral entry into host cell
0.62	GO:0034394	protein localization to cell surface
0.55	GO:0008228	opsonization
0.55	GO:0007186	G-protein coupled receptor signaling pathway
0.51	GO:0050830	defense response to Gram-positive bacterium
0.51	GO:0050829	defense response to Gram-negative bacterium

0.76	GO:0033691	sialic acid binding
0.64	GO:0008329	signaling pattern recognition receptor activity
0.58	GO:0030246	carbohydrate binding
0.58	GO:0001664	G-protein coupled receptor binding
0.54	GO:0003823	antigen binding
0.52	GO:0043394	proteoglycan binding
0.52	GO:0048306	calcium-dependent protein binding
0.49	GO:0001871	pattern binding
0.45	GO:0046872	metal ion binding
0.41	GO:0004252	serine-type endopeptidase activity

0.67	GO:0031232	extrinsic component of external side of plasma membrane
0.62	GO:0005581	collagen trimer
0.53	GO:0005576	extracellular region
0.43	GO:1904813	ficolin-1-rich granule lumen
0.42	GO:0034774	secretory granule lumen

0.41

GO:0004252

sp|O70503|DHB12_MOUSE
Very-long-chain 3-oxoacyl-CoA reductase
Search

HSD17B12

0.71	Very-long-chain 3-oxoacyl-CoA reductase-A

0.52	GO:0010811	positive regulation of cell-substrate adhesion
0.51	GO:0055114	oxidation-reduction process
0.50	GO:0030198	extracellular matrix organization
0.46	GO:0006703	estrogen biosynthetic process
0.41	GO:0006633	fatty acid biosynthetic process
0.35	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.32	GO:0019538	protein metabolic process
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.54	GO:0001968	fibronectin binding
0.52	GO:0016491	oxidoreductase activity
0.51	GO:0005518	collagen binding
0.51	GO:0008201	heparin binding
0.33	GO:0004252	serine-type endopeptidase activity
0.32	GO:0003735	structural constituent of ribosome

0.48	GO:0005578	proteinaceous extracellular matrix
0.41	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005739	mitochondrion
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.52

GO:0016491

sp|O70507|HCN4_MOUSE
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Search

HCN4

0.82	Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2

0.77	GO:0002027	regulation of heart rate
0.72	GO:0071805	potassium ion transmembrane transport
0.71	GO:0034765	regulation of ion transmembrane transport
0.69	GO:0006814	sodium ion transport
0.61	GO:0071321	cellular response to cGMP
0.60	GO:0042391	regulation of membrane potential
0.60	GO:0071320	cellular response to cAMP
0.59	GO:0086018	SA node cell to atrial cardiac muscle cell signaling
0.58	GO:0098659	inorganic cation import across plasma membrane
0.58	GO:0086004	regulation of cardiac muscle cell contraction

0.77	GO:0030552	cAMP binding
0.77	GO:0005249	voltage-gated potassium channel activity
0.63	GO:0005248	voltage-gated sodium channel activity
0.62	GO:0005222	intracellular cAMP activated cation channel activity
0.52	GO:0042802	identical protein binding
0.35	GO:0030165	PDZ domain binding
0.34	GO:0032947	protein complex scaffold activity
0.34	GO:0032403	protein complex binding

0.61	GO:0098855	HCN channel complex
0.53	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0030424	axon
0.40	GO:0043025	neuronal cell body
0.40	GO:0043679	axon terminus
0.38	GO:0030425	dendrite
0.37	GO:0098590	plasma membrane region
0.34	GO:0031256	leading edge membrane

sp|O70514|FGFP1_MOUSE
Fibroblast growth factor-binding protein 1
Search

FGFBP1

0.94	Fibroblast growth factor-binding protein 1

0.84	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway
0.73	GO:0008284	positive regulation of cell proliferation
0.45	GO:0007267	cell-cell signaling
0.42	GO:0008543	fibroblast growth factor receptor signaling pathway
0.41	GO:0008285	negative regulation of cell proliferation

0.81	GO:0017134	fibroblast growth factor binding
0.42	GO:0008201	heparin binding

0.70	GO:0009986	cell surface
0.62	GO:0005576	extracellular region
0.42	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|O70517|O70517_MOUSE
Putative uncharacterized protein variable group of 2-cell-stage gene family
Search

tr|O70518|O70518_MOUSE
2-cell-stage, variable group, member 3
Search

0.87	2-cell-stage, variable group, member 3

sp|O70546|KDM6A_MOUSE
Lysine-specific demethylase 6A
Search

KDM6A

0.93	Ubiquitously transcribed tetratricopeptide repeat protein X-linked transcript variant 4

0.85	GO:0071557	histone H3-K27 demethylation
0.56	GO:0060255	regulation of macromolecule metabolic process
0.56	GO:0032259	methylation
0.46	GO:0032525	somite rostral/caudal axis specification
0.46	GO:0003016	respiratory system process
0.46	GO:0048570	notochord morphogenesis
0.45	GO:0048333	mesodermal cell differentiation
0.44	GO:0001843	neural tube closure
0.44	GO:0035264	multicellular organism growth
0.44	GO:0060070	canonical Wnt signaling pathway

0.85	GO:0071558	histone demethylase activity (H3-K27 specific)
0.56	GO:0008168	methyltransferase activity
0.54	GO:0046872	metal ion binding
0.44	GO:0031490	chromatin DNA binding
0.43	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.42	GO:0042802	identical protein binding
0.35	GO:0051213	dioxygenase activity

0.45	GO:0044666	MLL3/4 complex
0.30	GO:0031224	intrinsic component of membrane

0.56

GO:0008168

sp|O70548|TELT_MOUSE
Telethonin
Search

TCAP

0.97	Telethonin

0.86	GO:0048769	sarcomerogenesis
0.86	GO:0035995	detection of muscle stretch
0.86	GO:0030241	skeletal muscle myosin thick filament assembly
0.86	GO:0048739	cardiac muscle fiber development
0.86	GO:0007512	adult heart development
0.86	GO:0030240	skeletal muscle thin filament assembly
0.85	GO:0030916	otic vesicle formation
0.85	GO:0003299	muscle hypertrophy in response to stress
0.85	GO:0014887	cardiac muscle adaptation
0.85	GO:0055003	cardiac myofibril assembly

0.87	GO:0070080	titin Z domain binding
0.86	GO:0051373	FATZ binding
0.86	GO:0031432	titin binding
0.85	GO:0036122	BMP binding
0.85	GO:0008307	structural constituent of muscle
0.83	GO:0044325	ion channel binding
0.78	GO:0030674	protein binding, bridging

0.84	GO:0030018	Z disc
0.38	GO:0005829	cytosol

sp|O70551|SRPK1_MOUSE
SRSF protein kinase 1
Search

SRPK1

0.91	SRSF protein kinase 1

0.61	GO:0006468	protein phosphorylation
0.59	GO:0045070	positive regulation of viral genome replication
0.59	GO:0045071	negative regulation of viral genome replication
0.55	GO:0050684	regulation of mRNA processing
0.52	GO:0007059	chromosome segregation
0.48	GO:0000245	spliceosomal complex assembly
0.48	GO:0035556	intracellular signal transduction
0.37	GO:0030154	cell differentiation
0.35	GO:0043484	regulation of RNA splicing
0.35	GO:0006997	nucleus organization

0.62	GO:0004672	protein kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0000287	magnesium ion binding
0.35	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.34	GO:0015116	sulfate transmembrane transporter activity

0.49	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.43	GO:0005886	plasma membrane
0.37	GO:0005783	endoplasmic reticulum
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|O70552|BTG4_MOUSE
Protein BTG4
Search

BTG4

0.97	BTG anti-proliferation factor 4

0.72	GO:0008285	negative regulation of cell proliferation
0.55	GO:0045930	negative regulation of mitotic cell cycle
0.35	GO:0007050	cell cycle arrest
0.34	GO:0030182	neuron differentiation

0.35

GO:0005515

protein binding

0.35	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|O70554|SPR2B_MOUSE
Small proline-rich protein 2B
Search

0.96	Late cornified envelope-like proline-rich protein 1

0.57	GO:0018149	peptide cross-linking
0.56	GO:0030216	keratinocyte differentiation
0.48	GO:0032355	response to estradiol
0.39	GO:0012501	programmed cell death
0.38	GO:0008585	female gonad development
0.34	GO:0009411	response to UV
0.34	GO:0051258	protein polymerization
0.34	GO:0007010	cytoskeleton organization
0.34	GO:0008360	regulation of cell shape
0.33	GO:0006508	proteolysis

0.46	GO:0005198	structural molecule activity
0.36	GO:0005515	protein binding
0.35	GO:0060090	molecular adaptor activity
0.34	GO:0070008	serine-type exopeptidase activity
0.34	GO:0004175	endopeptidase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0070001	aspartic-type peptidase activity
0.32	GO:0003676	nucleic acid binding

0.81	GO:0001533	cornified envelope
0.44	GO:0045095	keratin filament
0.40	GO:0005737	cytoplasm
0.40	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0070008

sp|O70555|SPR2D_MOUSE
Small proline-rich protein 2D
Search

0.97	Small proline-rich protein 2D

0.57	GO:0018149	peptide cross-linking
0.57	GO:0030216	keratinocyte differentiation
0.47	GO:0032355	response to estradiol
0.40	GO:0012501	programmed cell death
0.38	GO:0008585	female gonad development
0.35	GO:0009411	response to UV
0.34	GO:0051258	protein polymerization
0.33	GO:0007010	cytoskeleton organization
0.33	GO:0008360	regulation of cell shape
0.32	GO:0030001	metal ion transport

0.46	GO:0005198	structural molecule activity
0.35	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding
0.32	GO:0003700	DNA binding transcription factor activity

0.81	GO:0001533	cornified envelope
0.40	GO:0005737	cytoplasm
0.39	GO:0005634	nucleus
0.33	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

sp|O70556|SPR2E_MOUSE
Small proline-rich protein 2E
Search

0.97	Small proline-rich protein 2E

0.63	GO:0018149	peptide cross-linking
0.57	GO:0030216	keratinocyte differentiation
0.45	GO:0032355	response to estradiol
0.40	GO:0012501	programmed cell death
0.37	GO:0008585	female gonad development
0.34	GO:0009411	response to UV
0.34	GO:0051258	protein polymerization
0.33	GO:0071526	semaphorin-plexin signaling pathway
0.33	GO:0007010	cytoskeleton organization
0.33	GO:0008360	regulation of cell shape

0.46	GO:0005198	structural molecule activity
0.39	GO:0030674	protein binding, bridging
0.33	GO:0017154	semaphorin receptor activity
0.33	GO:0046983	protein dimerization activity
0.33	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.76	GO:0001533	cornified envelope
0.42	GO:0005737	cytoplasm
0.38	GO:0005634	nucleus
0.35	GO:0070062	extracellular exosome
0.34	GO:0012505	endomembrane system
0.30	GO:0016021	integral component of membrane

sp|O70557|SPR2F_MOUSE
Small proline-rich protein 2F
Search

0.97	Small proline-rich protein 2F

0.57	GO:0018149	peptide cross-linking
0.57	GO:0030216	keratinocyte differentiation
0.47	GO:0032355	response to estradiol
0.41	GO:0012501	programmed cell death
0.38	GO:0008585	female gonad development
0.35	GO:0009411	response to UV
0.34	GO:0051258	protein polymerization
0.33	GO:0007010	cytoskeleton organization
0.33	GO:0008360	regulation of cell shape
0.32	GO:0006508	proteolysis

0.46	GO:0005198	structural molecule activity
0.35	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0070001	aspartic-type peptidase activity
0.32	GO:0003676	nucleic acid binding
0.32	GO:0004175	endopeptidase activity

0.82	GO:0001533	cornified envelope
0.41	GO:0005737	cytoplasm
0.39	GO:0005634	nucleus
0.33	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

sp|O70558|SPR2G_MOUSE
Small proline-rich protein 2G
Search

0.97	Small proline-rich protein 2G

0.58	GO:0018149	peptide cross-linking
0.57	GO:0030216	keratinocyte differentiation
0.48	GO:0032355	response to estradiol
0.41	GO:0012501	programmed cell death
0.38	GO:0008585	female gonad development
0.35	GO:0009411	response to UV
0.34	GO:0051258	protein polymerization
0.34	GO:0007010	cytoskeleton organization
0.33	GO:0008360	regulation of cell shape
0.32	GO:0030001	metal ion transport

0.46	GO:0005198	structural molecule activity
0.36	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding
0.32	GO:0003700	DNA binding transcription factor activity

0.83	GO:0001533	cornified envelope
0.41	GO:0005737	cytoplasm
0.40	GO:0005634	nucleus
0.33	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

sp|O70559|SPR2H_MOUSE
Small proline-rich protein 2H
Search

0.90	small proline-rich protein 4

0.58	GO:0018149	peptide cross-linking
0.58	GO:0030216	keratinocyte differentiation
0.50	GO:0032355	response to estradiol
0.39	GO:0012501	programmed cell death
0.38	GO:0008585	female gonad development
0.35	GO:0001558	regulation of cell growth
0.34	GO:0009411	response to UV
0.34	GO:0051258	protein polymerization
0.33	GO:0007010	cytoskeleton organization
0.33	GO:0008360	regulation of cell shape

0.47	GO:0005198	structural molecule activity
0.35	GO:0005515	protein binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0070001	aspartic-type peptidase activity
0.32	GO:0004175	endopeptidase activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003676	nucleic acid binding

0.82	GO:0001533	cornified envelope
0.41	GO:0005737	cytoplasm
0.40	GO:0005634	nucleus
0.35	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|O70560|SPR2I_MOUSE
Small proline-rich protein 2I
Search

0.97	Small proline-rich protein 2I

0.63	GO:0018149	peptide cross-linking
0.57	GO:0030216	keratinocyte differentiation
0.45	GO:0032355	response to estradiol
0.40	GO:0012501	programmed cell death
0.37	GO:0008585	female gonad development
0.34	GO:0009411	response to UV
0.34	GO:0051258	protein polymerization
0.33	GO:0007010	cytoskeleton organization
0.33	GO:0008360	regulation of cell shape
0.32	GO:0006508	proteolysis

0.46	GO:0005198	structural molecule activity
0.39	GO:0030674	protein binding, bridging
0.33	GO:0046983	protein dimerization activity
0.33	GO:0046872	metal ion binding
0.32	GO:0070001	aspartic-type peptidase activity
0.32	GO:0003676	nucleic acid binding
0.32	GO:0004175	endopeptidase activity
0.32	GO:0003700	DNA binding transcription factor activity

0.77	GO:0001533	cornified envelope
0.42	GO:0005737	cytoplasm
0.38	GO:0005634	nucleus
0.35	GO:0005615	extracellular space
0.35	GO:1903561	extracellular vesicle
0.34	GO:0012505	endomembrane system
0.30	GO:0016021	integral component of membrane

sp|O70561|SPR2J_MOUSE
Putative small proline-rich protein 2J
Search

0.61	Small proline-rich protein 2I-like

0.85	GO:0032355	response to estradiol
0.56	GO:0031424	keratinization
0.55	GO:0018149	peptide cross-linking

0.44

GO:0005198

structural molecule activity

0.66	GO:0001533	cornified envelope
0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm

sp|O70562|SPR2K_MOUSE
Small proline-rich protein 2K
Search

0.97	Small proline-rich protein 2K

0.54	GO:0018149	peptide cross-linking
0.54	GO:0030216	keratinocyte differentiation
0.45	GO:0032355	response to estradiol
0.40	GO:0012501	programmed cell death
0.37	GO:0008585	female gonad development
0.34	GO:0009411	response to UV
0.34	GO:0051258	protein polymerization
0.33	GO:0007010	cytoskeleton organization
0.33	GO:0008360	regulation of cell shape

0.44	GO:0005198	structural molecule activity
0.35	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.78	GO:0001533	cornified envelope
0.40	GO:0005737	cytoplasm
0.38	GO:0005634	nucleus
0.33	GO:0033644	host cell membrane
0.33	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

sp|O70566|DIAP2_MOUSE
Protein diaphanous homolog 2
Search

DIAPH2

0.94	Diaphanous

0.78	GO:0007292	female gamete generation
0.74	GO:0030036	actin cytoskeleton organization
0.72	GO:0097435	supramolecular fiber organization
0.43	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.43	GO:0060027	convergent extension involved in gastrulation
0.42	GO:0042074	cell migration involved in gastrulation
0.42	GO:0040001	establishment of mitotic spindle localization
0.41	GO:0051258	protein polymerization
0.40	GO:0051056	regulation of small GTPase mediated signal transduction
0.37	GO:0007281	germ cell development

0.76	GO:0017048	Rho GTPase binding
0.73	GO:0003779	actin binding
0.36	GO:0005102	receptor binding
0.35	GO:0030545	receptor regulator activity
0.34	GO:0045296	cadherin binding

0.49	GO:0005730	nucleolus
0.48	GO:0005783	endoplasmic reticulum
0.35	GO:0005769	early endosome
0.34	GO:0005829	cytosol
0.34	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|O70570|PIGR_MOUSE
Polymeric immunoglobulin receptor
Search

PIGR

0.93	Polymeric immunoglobulin receptor

0.79	GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor
0.75	GO:0038093	Fc receptor signaling pathway
0.74	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
0.73	GO:0043113	receptor clustering
0.73	GO:0007173	epidermal growth factor receptor signaling pathway
0.49	GO:0001895	retina homeostasis
0.43	GO:0043312	neutrophil degranulation

0.80	GO:0001792	polymeric immunoglobulin receptor activity
0.45	GO:0005154	epidermal growth factor receptor binding

0.67	GO:0043235	receptor complex
0.63	GO:0005615	extracellular space
0.50	GO:0005886	plasma membrane
0.47	GO:1903561	extracellular vesicle
0.45	GO:0044433	cytoplasmic vesicle part
0.44	GO:0098805	whole membrane
0.44	GO:0098588	bounding membrane of organelle
0.44	GO:0055037	recycling endosome
0.43	GO:0005766	primary lysosome
0.42	GO:0030133	transport vesicle

sp|O70571|PDK4_MOUSE
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial
Search

PDK4

0.97	Pyruvate dehydrogenase kinase isozyme 4

0.72	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate
0.68	GO:0008286	insulin receptor signaling pathway
0.66	GO:0010906	regulation of glucose metabolic process
0.63	GO:2000811	negative regulation of anoikis
0.63	GO:0042593	glucose homeostasis
0.63	GO:0071398	cellular response to fatty acid
0.63	GO:0046320	regulation of fatty acid oxidation
0.63	GO:0045124	regulation of bone resorption
0.62	GO:0006885	regulation of pH
0.62	GO:0031669	cellular response to nutrient levels

0.59	GO:0016301	kinase activity
0.51	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.49	GO:0140096	catalytic activity, acting on a protein
0.46	GO:0032559	adenyl ribonucleotide binding
0.46	GO:0008144	drug binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0042803	protein homodimerization activity
0.34	GO:0032403	protein complex binding
0.34	GO:0046982	protein heterodimerization activity

0.51	GO:0044429	mitochondrial part
0.48	GO:0019866	organelle inner membrane
0.47	GO:0045254	pyruvate dehydrogenase complex
0.45	GO:0031974	membrane-enclosed lumen
0.43	GO:0005829	cytosol
0.42	GO:0044428	nuclear part

0.51

GO:0016773

sp|O70572|NSMA_MOUSE
Sphingomyelin phosphodiesterase 2
Search

SMPD2

0.97	Sphingomyelin phosphodiesterase 2, neutral membrane (Neutral sphingomyelinase)

0.43	GO:0046513	ceramide biosynthetic process
0.41	GO:0009612	response to mechanical stimulus
0.40	GO:0006684	sphingomyelin metabolic process
0.38	GO:0071502	cellular response to temperature stimulus
0.38	GO:0035556	intracellular signal transduction
0.38	GO:0090520	sphingolipid mediated signaling pathway
0.37	GO:2000304	positive regulation of ceramide biosynthetic process
0.36	GO:0071466	cellular response to xenobiotic stimulus
0.36	GO:0043065	positive regulation of apoptotic process
0.36	GO:0006687	glycosphingolipid metabolic process

0.61	GO:0004767	sphingomyelin phosphodiesterase activity
0.35	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding
0.33	GO:0004527	exonuclease activity
0.32	GO:0004519	endonuclease activity
0.31	GO:0003676	nucleic acid binding

0.41	GO:0005901	caveola
0.36	GO:0005794	Golgi apparatus
0.34	GO:0005887	integral component of plasma membrane

0.61	EC:3.1.4.12	GO:0004767
0.61	KEGG:R02541	GO:0004767

sp|O70576|STAG3_MOUSE
Cohesin subunit SA-3
Search

STAG3

0.92	Stromal antigen 3

0.81	GO:0007129	synapsis
0.80	GO:0034502	protein localization to chromosome
0.51	GO:0032876	negative regulation of DNA endoreduplication
0.50	GO:1901673	regulation of mitotic spindle assembly
0.47	GO:0007062	sister chromatid cohesion
0.39	GO:0019827	stem cell population maintenance
0.38	GO:0006366	transcription by RNA polymerase II
0.38	GO:0045944	positive regulation of transcription by RNA polymerase II
0.37	GO:0032259	methylation

0.39	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.38	GO:0003682	chromatin binding
0.37	GO:0008168	methyltransferase activity

0.86	GO:0000802	transverse filament
0.85	GO:0034991	nuclear meiotic cohesin complex
0.84	GO:0000800	lateral element
0.84	GO:0001673	male germ cell nucleus
0.50	GO:0097431	mitotic spindle pole
0.49	GO:0016363	nuclear matrix
0.44	GO:0000785	chromatin
0.30	GO:0016020	membrane

0.37

GO:0008168

sp|O70577|S22A2_MOUSE
Solute carrier family 22 member 2
Search

SLC22A2

0.96	Solute carrier family 22 member 2

0.58	GO:0015695	organic cation transport
0.55	GO:0015872	dopamine transport
0.55	GO:0055085	transmembrane transport
0.55	GO:0015874	norepinephrine transport
0.54	GO:1901374	acetate ester transport
0.47	GO:0006836	neurotransmitter transport
0.46	GO:0015711	organic anion transport
0.39	GO:0048241	epinephrine transport
0.36	GO:0051260	protein homooligomerization
0.35	GO:0007589	body fluid secretion

0.60	GO:0015101	organic cation transmembrane transporter activity
0.55	GO:0005329	dopamine transmembrane transporter activity
0.55	GO:0005333	norepinephrine transmembrane transporter activity
0.54	GO:1901375	acetate ester transmembrane transporter activity
0.48	GO:0005326	neurotransmitter transporter activity
0.47	GO:0008514	organic anion transmembrane transporter activity
0.45	GO:0015291	secondary active transmembrane transporter activity
0.36	GO:0042803	protein homodimerization activity
0.35	GO:0005496	steroid binding

0.45	GO:0005887	integral component of plasma membrane
0.41	GO:0016323	basolateral plasma membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0098793	presynapse

sp|O70578|CCG1_MOUSE
Voltage-dependent calcium channel gamma-1 subunit
Search

CACNG1

0.46	Voltage-dependent calcium channel gamma-1 subunit

0.76	GO:0070588	calcium ion transmembrane transport
0.75	GO:0034765	regulation of ion transmembrane transport
0.61	GO:0070296	sarcoplasmic reticulum calcium ion transport
0.35	GO:0061337	cardiac conduction
0.35	GO:0006936	muscle contraction

0.81	GO:0005245	voltage-gated calcium channel activity
0.34	GO:0005515	protein binding

0.80	GO:0005891	voltage-gated calcium channel complex
0.35	GO:0030315	T-tubule

sp|O70579|PM34_MOUSE
Peroxisomal membrane protein PMP34
Search

SLC25A17

0.92	Solute carrier family 25 (Mitochondrial carrier peroxisomal membrane protein, 34kDa), member 17

0.77	GO:0035352	NAD transmembrane transport
0.77	GO:0080121	AMP transport
0.76	GO:0035350	FAD transmembrane transport
0.76	GO:0071106	adenosine 3',5'-bisphosphate transmembrane transport
0.76	GO:0015880	coenzyme A transport
0.72	GO:0015866	ADP transport
0.71	GO:0015867	ATP transport
0.68	GO:0015908	fatty acid transport
0.65	GO:0006635	fatty acid beta-oxidation
0.53	GO:0006839	mitochondrial transport

0.79	GO:0044610	FMN transmembrane transporter activity
0.77	GO:0051724	NAD transmembrane transporter activity
0.77	GO:0080122	AMP transmembrane transporter activity
0.76	GO:0015230	FAD transmembrane transporter activity
0.76	GO:0071077	adenosine 3',5'-bisphosphate transmembrane transporter activity
0.72	GO:0015217	ADP transmembrane transporter activity
0.72	GO:0005347	ATP transmembrane transporter activity
0.65	GO:0051087	chaperone binding

0.69	GO:0005779	integral component of peroxisomal membrane
0.54	GO:0005739	mitochondrion
0.46	GO:0031967	organelle envelope

sp|O70582|LX12B_MOUSE
Arachidonate 12-lipoxygenase, 12R-type
Search

0.97	Epidermis-type lipoxygenase 3

0.72	GO:0019372	lipoxygenase pathway
0.72	GO:0043651	linoleic acid metabolic process
0.69	GO:0019369	arachidonic acid metabolic process
0.66	GO:0061436	establishment of skin barrier
0.65	GO:0046513	ceramide biosynthetic process
0.62	GO:0070257	positive regulation of mucus secretion
0.58	GO:0009967	positive regulation of signal transduction
0.55	GO:0043408	regulation of MAPK cascade
0.55	GO:0006497	protein lipidation
0.55	GO:0051122	hepoxilin biosynthetic process

0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.61	GO:0005506	iron ion binding
0.52	GO:0051120	hepoxilin A3 synthase activity
0.42	GO:0005509	calcium ion binding
0.36	GO:0005515	protein binding
0.35	GO:0008289	lipid binding
0.34	GO:0016829	lyase activity

0.44	GO:0019898	extrinsic component of membrane
0.43	GO:0005829	cytosol
0.42	GO:0005856	cytoskeleton
0.38	GO:0005886	plasma membrane
0.35	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.75

EC:1.13.11

GO:0016702

sp|O70583|TRI18_MOUSE
E3 ubiquitin-protein ligase Midline-1
Search

MID1

0.97	E3 ubiquitin-protein ligase Midline-1

0.58	GO:0035372	protein localization to microtubule
0.55	GO:0032874	positive regulation of stress-activated MAPK cascade
0.51	GO:0007026	negative regulation of microtubule depolymerization
0.36	GO:0045087	innate immune response
0.35	GO:0046597	negative regulation of viral entry into host cell
0.35	GO:1902187	negative regulation of viral release from host cell
0.35	GO:0032897	negative regulation of viral transcription
0.34	GO:0019221	cytokine-mediated signaling pathway
0.34	GO:0007389	pattern specification process
0.34	GO:0051092	positive regulation of NF-kappaB transcription factor activity

0.62	GO:0008270	zinc ion binding
0.55	GO:0051219	phosphoprotein binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.51	GO:0042803	protein homodimerization activity
0.51	GO:0008017	microtubule binding
0.51	GO:0046982	protein heterodimerization activity
0.48	GO:0016874	ligase activity
0.34	GO:0016740	transferase activity

0.55	GO:0005881	cytoplasmic microtubule
0.34	GO:0005819	spindle
0.34	GO:0005875	microtubule associated complex
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.48

GO:0016874

sp|O70584|NKX28_MOUSE
Homeobox protein Nkx-2.8
Search

NKX2-8

0.93	Homeobox protein Nkx-2.8

0.59	GO:0035295	tube development
0.58	GO:0030182	neuron differentiation
0.58	GO:0050680	negative regulation of epithelial cell proliferation
0.57	GO:0045944	positive regulation of transcription by RNA polymerase II
0.57	GO:0048468	cell development
0.56	GO:0048513	animal organ development
0.56	GO:0060541	respiratory system development
0.55	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.54	GO:0120036	plasma membrane bounded cell projection organization
0.53	GO:0006366	transcription by RNA polymerase II

0.64	GO:0043565	sequence-specific DNA binding
0.58	GO:0044212	transcription regulatory region DNA binding
0.56	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0003690	double-stranded DNA binding
0.46	GO:0003713	transcription coactivator activity
0.45	GO:0003682	chromatin binding
0.44	GO:0008134	transcription factor binding
0.36	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.33	GO:0005267	potassium channel activity
0.33	GO:0004252	serine-type endopeptidase activity

0.61	GO:0005634	nucleus
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

GO:0004252

sp|O70585|DTNB_MOUSE
Dystrobrevin beta
Search

DTNB

0.88	Dystrobrevin beta

0.62	GO:0008270	zinc ion binding
0.35	GO:0005515	protein binding

0.49	GO:0045202	synapse
0.47	GO:0005737	cytoplasm

sp|O70589|CSKP_MOUSE
Peripheral plasma membrane protein CASK
Search

CASK

0.81	Calcium/calmodulin-dependent serine protein kinase a

0.63	GO:0006468	protein phosphorylation
0.57	GO:0010839	negative regulation of keratinocyte proliferation
0.56	GO:0001953	negative regulation of cell-matrix adhesion
0.55	GO:0061045	negative regulation of wound healing
0.54	GO:0090280	positive regulation of calcium ion import
0.53	GO:0090288	negative regulation of cellular response to growth factor stimulus
0.53	GO:0070509	calcium ion import
0.49	GO:0045944	positive regulation of transcription by RNA polymerase II

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0042043	neurexin family protein binding

0.56	GO:0005652	nuclear lamina
0.54	GO:0016363	nuclear matrix
0.53	GO:0005604	basement membrane
0.52	GO:0016323	basolateral plasma membrane
0.51	GO:0005911	cell-cell junction
0.49	GO:0005730	nucleolus
0.49	GO:0045202	synapse
0.47	GO:0031982	vesicle
0.46	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|O70591|PFD2_MOUSE
Prefoldin subunit 2
Search

PFDN2

0.89	Prefoldin subunit 2

0.69	GO:0006457	protein folding
0.52	GO:0051495	positive regulation of cytoskeleton organization
0.37	GO:0007021	tubulin complex assembly
0.34	GO:0007155	cell adhesion
0.33	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.33	GO:0044409	entry into host
0.33	GO:0019058	viral life cycle
0.33	GO:0006661	phosphatidylinositol biosynthetic process
0.32	GO:0046034	ATP metabolic process

0.71	GO:0051082	unfolded protein binding
0.58	GO:0044183	protein binding involved in protein folding
0.36	GO:0015631	tubulin binding
0.33	GO:0003723	RNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0016272	prefoldin complex
0.48	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.44	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.33	GO:0070772	PAS complex
0.30	GO:0031224	intrinsic component of membrane

tr|O70616|O70616_MOUSE
AF067061 protein
Search

tr|O70618|O70618_MOUSE
CDNA sequence AF067063
Search

tr|O70619|O70619_MOUSE
2-cell-stage, variable group, member 1
Search

0.87	2-cell-stage, variable group, member 1

sp|O70622|RTN2_MOUSE
Reticulon-2
Search

RTN2

0.66

Reticulon

0.54	GO:0046324	regulation of glucose import
0.49	GO:0065002	intracellular protein transmembrane transport
0.43	GO:0071787	endoplasmic reticulum tubular network formation
0.43	GO:0021558	trochlear nerve development
0.42	GO:0021557	oculomotor nerve development
0.42	GO:0021554	optic nerve development
0.42	GO:0031103	axon regeneration
0.42	GO:0048884	neuromast development
0.41	GO:0048703	embryonic viscerocranium morphogenesis
0.41	GO:0008045	motor neuron axon guidance

0.39	GO:0005199	structural constituent of cell wall
0.34	GO:0102250	linear malto-oligosaccharide phosphorylase activity
0.34	GO:0102499	SHG alpha-glucan phosphorylase activity
0.34	GO:0008184	glycogen phosphorylase activity
0.33	GO:0030170	pyridoxal phosphate binding
0.33	GO:0005515	protein binding

0.71	GO:0005789	endoplasmic reticulum membrane
0.57	GO:0014802	terminal cisterna
0.55	GO:0030315	T-tubule
0.36	GO:0000139	Golgi membrane
0.34	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|O70624|MYOC_MOUSE
Myocilin
Search

MYOC

0.97	Myocilin, trabecular meshwork-inducible glucocorticoid response

0.83	GO:0051492	regulation of stress fiber assembly
0.82	GO:0001952	regulation of cell-matrix adhesion
0.79	GO:0030335	positive regulation of cell migration
0.65	GO:0038133	ERBB2-ERBB3 signaling pathway
0.65	GO:0014734	skeletal muscle hypertrophy
0.63	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade
0.62	GO:0051901	positive regulation of mitochondrial depolarization
0.62	GO:0045162	clustering of voltage-gated sodium channels
0.61	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.61	GO:0032232	negative regulation of actin filament bundle assembly

0.61	GO:0032027	myosin light chain binding
0.60	GO:0001968	fibronectin binding
0.59	GO:0005109	frizzled binding
0.58	GO:0030971	receptor tyrosine kinase binding
0.37	GO:0046872	metal ion binding
0.35	GO:0045296	cadherin binding
0.35	GO:0042803	protein homodimerization activity
0.34	GO:0004930	G-protein coupled receptor activity
0.34	GO:0030246	carbohydrate binding
0.30	GO:0003824	catalytic activity

0.71	GO:0005615	extracellular space
0.62	GO:0033268	node of Ranvier
0.56	GO:0005758	mitochondrial intermembrane space
0.55	GO:0005741	mitochondrial outer membrane
0.53	GO:0031012	extracellular matrix
0.53	GO:0031410	cytoplasmic vesicle
0.52	GO:0005794	Golgi apparatus
0.52	GO:0005783	endoplasmic reticulum
0.47	GO:0019866	organelle inner membrane
0.44	GO:1903561	extracellular vesicle

sp|O70628|PDE9A_MOUSE
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
Search

PDE9A

0.58	Phosphodiesterase

0.60	GO:0007165	signal transduction
0.53	GO:0046069	cGMP catabolic process
0.52	GO:0014742	positive regulation of muscle hypertrophy
0.51	GO:0010611	regulation of cardiac muscle hypertrophy

0.79	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.53	GO:0046872	metal ion binding
0.36	GO:0042802	identical protein binding

0.50	GO:0042383	sarcolemma
0.38	GO:0043204	perikaryon
0.38	GO:0032587	ruffle membrane
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005794	Golgi apparatus
0.36	GO:0005783	endoplasmic reticulum
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.79

GO:0004114

sp|O88174|MCP_MOUSE
Membrane cofactor protein
Search

CD46

0.97	membrane cofactor protein isoform X2

0.79	GO:0007338	single fertilization
0.56	GO:0002449	lymphocyte mediated immunity
0.56	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
0.53	GO:0050778	positive regulation of immune response
0.52	GO:0043380	regulation of memory T cell differentiation
0.52	GO:0032613	interleukin-10 production
0.52	GO:0035581	sequestering of extracellular ligand from receptor
0.52	GO:0045591	positive regulation of regulatory T cell differentiation
0.51	GO:0071636	positive regulation of transforming growth factor beta production
0.51	GO:0032733	positive regulation of interleukin-10 production

0.48	GO:0045296	cadherin binding
0.40	GO:0001848	complement binding
0.38	GO:0004175	endopeptidase activity
0.38	GO:0104005	hijacked molecular function
0.38	GO:0004857	enzyme inhibitor activity
0.35	GO:0004872	receptor activity

0.85	GO:0002079	inner acrosomal membrane
0.75	GO:0009986	cell surface
0.43	GO:0005576	extracellular region
0.41	GO:0005925	focal adhesion
0.39	GO:0005886	plasma membrane
0.37	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

sp|O88186|GPIX_MOUSE
Platelet glycoprotein IX
Search

GP9

0.97	Glycoprotein Ib platelet beta subunit

0.42	GO:0007596	blood coagulation
0.40	GO:0007155	cell adhesion
0.39	GO:0048699	generation of neurons
0.39	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.39	GO:0000904	cell morphogenesis involved in differentiation
0.38	GO:0120036	plasma membrane bounded cell projection organization
0.38	GO:0072376	protein activation cascade
0.38	GO:0001775	cell activation
0.35	GO:0010172	embryonic body morphogenesis
0.35	GO:0046426	negative regulation of JAK-STAT cascade

0.36	GO:0004180	carboxypeptidase activity
0.35	GO:0005515	protein binding
0.35	GO:0004860	protein kinase inhibitor activity
0.34	GO:0004601	peroxidase activity
0.33	GO:0020037	heme binding
0.32	GO:0046872	metal ion binding

0.38	GO:0031012	extracellular matrix
0.38	GO:0005615	extracellular space
0.36	GO:0005887	integral component of plasma membrane
0.32	GO:0005737	cytoplasm

0.34	EC:1.11.1.7	GO:0004601
0.34	KEGG:R03532	GO:0004601

sp|O88188|LY86_MOUSE
Lymphocyte antigen 86
Search

LY86

0.96	Lymphocyte antigen 86

0.87	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway
0.46	GO:0006954	inflammatory response
0.45	GO:0045087	innate immune response
0.41	GO:0006959	humoral immune response
0.40	GO:0008283	cell proliferation
0.40	GO:0006915	apoptotic process

0.42

GO:0005515

protein binding

0.44	GO:0005615	extracellular space
0.35	GO:0005886	plasma membrane

sp|O88196|TTC3_MOUSE
E3 ubiquitin-protein ligase TTC3
Search

TTC3

0.92	Tetratricopeptide repeat protein 3

0.80	GO:0070936	protein K48-linked ubiquitination
0.70	GO:0006511	ubiquitin-dependent protein catabolic process

0.70

GO:0004842

ubiquitin-protein transferase activity

0.68	GO:0005730	nucleolus
0.64	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.70

GO:0004842

sp|O88199|CHST3_MOUSE
Carbohydrate sulfotransferase 3
Search

CHST3

0.55	Carbohydrate sulfotransferase 3

0.62	GO:1903510	mucopolysaccharide metabolic process
0.61	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process
0.59	GO:0005975	carbohydrate metabolic process
0.52	GO:0006790	sulfur compound metabolic process
0.51	GO:0006024	glycosaminoglycan biosynthetic process
0.46	GO:0043436	oxoacid metabolic process
0.38	GO:0043029	T cell homeostasis
0.36	GO:0014012	peripheral nervous system axon regeneration
0.35	GO:0051272	positive regulation of cellular component movement
0.34	GO:0006954	inflammatory response

0.78	GO:0008146	sulfotransferase activity
0.33	GO:0005044	scavenger receptor activity

0.72	GO:0000139	Golgi membrane
0.33	GO:0005802	trans-Golgi network
0.30	GO:0016021	integral component of membrane

0.78

GO:0008146

sp|O88200|CLC11_MOUSE
C-type lectin domain family 11 member A
Search

CLEC11A

0.97	Stem cell growth factor; lymphocyte secreted C-type lectin

0.64	GO:0008284	positive regulation of cell proliferation
0.62	GO:0010469	regulation of receptor activity
0.46	GO:0001503	ossification

0.64	GO:0008083	growth factor activity
0.63	GO:0030246	carbohydrate binding

0.55	GO:0005576	extracellular region
0.36	GO:0005737	cytoplasm

sp|O88207|CO5A1_MOUSE
Collagen alpha-1(V) chain
Search

COL5A1

0.81	Collagen type XI alpha 1 chain

0.61	GO:0045112	integrin biosynthetic process
0.59	GO:0030199	collagen fibril organization
0.59	GO:0035989	tendon development
0.59	GO:1903225	negative regulation of endodermal cell differentiation
0.59	GO:0032964	collagen biosynthetic process
0.58	GO:0035313	wound healing, spreading of epidermal cells
0.56	GO:0090596	sensory organ morphogenesis
0.55	GO:0043588	skin development
0.54	GO:0003007	heart morphogenesis
0.53	GO:0001654	eye development

0.80	GO:0005201	extracellular matrix structural constituent
0.58	GO:0048407	platelet-derived growth factor binding
0.57	GO:0043394	proteoglycan binding
0.55	GO:0008201	heparin binding
0.35	GO:0005178	integrin binding
0.32	GO:0046872	metal ion binding

0.74	GO:0005581	collagen trimer
0.62	GO:0098643	banded collagen fibril
0.51	GO:0005604	basement membrane
0.50	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:0005788	endoplasmic reticulum lumen

tr|O88222|O88222_MOUSE
Mszf72 (Fragment)
Search

0.50	GO:1903506	regulation of nucleic acid-templated transcription
0.50	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.50	GO:0010468	regulation of gene expression
0.38	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage
0.35	GO:0032501	multicellular organismal process
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:1902679	negative regulation of RNA biosynthetic process
0.34	GO:0048856	anatomical structure development
0.34	GO:0044092	negative regulation of molecular function
0.33	GO:0009593	detection of chemical stimulus

0.51	GO:0003676	nucleic acid binding
0.49	GO:0046872	metal ion binding
0.39	GO:0003700	DNA binding transcription factor activity
0.36	GO:0042826	histone deacetylase binding
0.35	GO:0003682	chromatin binding
0.34	GO:0004984	olfactory receptor activity
0.33	GO:0005543	phospholipid binding
0.33	GO:0004930	G-protein coupled receptor activity

0.42	GO:0005622	intracellular
0.39	GO:0043227	membrane-bounded organelle
0.38	GO:0099512	supramolecular fiber
0.36	GO:0044422	organelle part
0.36	GO:0043228	non-membrane-bounded organelle
0.35	GO:0031974	membrane-enclosed lumen
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|O88229|O88229_MOUSE
Mszf79-1 (Fragment)
Search

0.49	GO:1903506	regulation of nucleic acid-templated transcription
0.49	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.48	GO:0010468	regulation of gene expression
0.36	GO:0006996	organelle organization
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:0022604	regulation of cell morphogenesis
0.35	GO:0018022	peptidyl-lysine methylation
0.35	GO:0051321	meiotic cell cycle
0.33	GO:0006468	protein phosphorylation

0.51	GO:0003676	nucleic acid binding
0.46	GO:0046872	metal ion binding
0.40	GO:0003700	DNA binding transcription factor activity
0.35	GO:0018024	histone-lysine N-methyltransferase activity
0.33	GO:0004672	protein kinase activity
0.33	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005622	intracellular
0.35	GO:0043227	membrane-bounded organelle
0.33	GO:0043228	non-membrane-bounded organelle

0.35

GO:0018024

tr|O88245|O88245_MOUSE
Mszf85 (Fragment)
Search

0.23	Zinc finger protein (Fragment)

0.51	GO:1903506	regulation of nucleic acid-templated transcription
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.50	GO:0010468	regulation of gene expression
0.36	GO:0014909	smooth muscle cell migration
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:0048745	smooth muscle tissue development
0.36	GO:0060325	face morphogenesis
0.36	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.35	GO:0001570	vasculogenesis
0.35	GO:0060021	palate development

0.51	GO:0003676	nucleic acid binding
0.47	GO:0046872	metal ion binding
0.44	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005515	protein binding

0.41	GO:0005622	intracellular
0.36	GO:0043227	membrane-bounded organelle

tr|O88253|O88253_MOUSE
Mszf39 (Fragment)
Search

0.37	Zinc finger protein (Fragment)

0.49	GO:1903506	regulation of nucleic acid-templated transcription
0.49	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.48	GO:0010468	regulation of gene expression
0.38	GO:0030097	hemopoiesis
0.37	GO:0006351	transcription, DNA-templated
0.35	GO:0006468	protein phosphorylation

0.51	GO:0003676	nucleic acid binding
0.46	GO:0046872	metal ion binding
0.40	GO:0003700	DNA binding transcription factor activity
0.35	GO:0004672	protein kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

tr|O88255|O88255_MOUSE
Mszf57 (Fragment)
Search

0.11	Zinc finger protein 441 (Fragment)

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.39	GO:0006351	transcription, DNA-templated
0.37	GO:0014022	neural plate elongation
0.36	GO:0060029	convergent extension involved in organogenesis
0.36	GO:0060028	convergent extension involved in axis elongation
0.36	GO:0060669	embryonic placenta morphogenesis
0.36	GO:0060027	convergent extension involved in gastrulation
0.34	GO:1902679	negative regulation of RNA biosynthetic process

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.40	GO:0003700	DNA binding transcription factor activity
0.36	GO:0001222	transcription corepressor binding

0.43	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle

sp|O88271|CFDP1_MOUSE
Craniofacial development protein 1
Search

CFDP1

0.95	Craniofacial development protein 1

0.67	GO:0007275	multicellular organism development
0.58	GO:2000270	negative regulation of fibroblast apoptotic process
0.51	GO:0042127	regulation of cell proliferation
0.49	GO:0007155	cell adhesion
0.48	GO:0008360	regulation of cell shape

0.76	GO:0000777	condensed chromosome kinetochore
0.36	GO:0005604	basement membrane

sp|O88273|GREM2_MOUSE
Gremlin-2
Search

GREM2

0.96	Gremlin 2, DAN family BMP antagonist b

0.70	GO:0048263	determination of dorsal identity
0.68	GO:0010469	regulation of receptor activity
0.67	GO:0038098	sequestering of BMP from receptor via BMP binding
0.63	GO:1900120	regulation of receptor binding
0.63	GO:0010172	embryonic body morphogenesis
0.58	GO:0019221	cytokine-mediated signaling pathway
0.52	GO:1901213	regulation of transcription from RNA polymerase II promoter involved in heart development
0.50	GO:0090291	negative regulation of osteoclast proliferation
0.50	GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis
0.50	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation

0.69	GO:0036122	BMP binding
0.69	GO:0005125	cytokine activity
0.60	GO:0008201	heparin binding
0.59	GO:0042803	protein homodimerization activity
0.50	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.50	GO:0043184	vascular endothelial growth factor receptor 2 binding
0.35	GO:0016015	morphogen activity

0.66	GO:0005615	extracellular space
0.45	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|O88282|BCL6B_MOUSE
B-cell CLL/lymphoma 6 member B protein
Search

BCL6B

0.91	B-cell CLL/lymphoma 6, member B

0.61	GO:0000122	negative regulation of transcription by RNA polymerase II
0.59	GO:0042092	type 2 immune response
0.54	GO:0050727	regulation of inflammatory response
0.52	GO:0042127	regulation of cell proliferation
0.52	GO:0045595	regulation of cell differentiation
0.47	GO:0032764	negative regulation of mast cell cytokine production
0.46	GO:0048294	negative regulation of isotype switching to IgE isotypes
0.46	GO:0002467	germinal center formation
0.46	GO:0000060	protein import into nucleus, translocation
0.46	GO:0002829	negative regulation of type 2 immune response

0.64	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.60	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.45	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding
0.43	GO:0031490	chromatin DNA binding
0.42	GO:0042802	identical protein binding
0.35	GO:0046872	metal ion binding
0.33	GO:0005179	hormone activity

0.50	GO:0005634	nucleus
0.42	GO:0005657	replication fork
0.41	GO:0005794	Golgi apparatus
0.40	GO:0070013	intracellular organelle lumen
0.32	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|O88286|WIZ_MOUSE
Protein Wiz
Search

sp|O88291|ZN326_MOUSE
DBIRD complex subunit ZNF326
Search

ZNF326

0.88	DBIRD complex subunit ZNF326

0.62	GO:0043484	regulation of RNA splicing
0.58	GO:0032784	regulation of DNA-templated transcription, elongation
0.55	GO:0008380	RNA splicing
0.53	GO:0006397	mRNA processing
0.44	GO:0006351	transcription, DNA-templated
0.42	GO:0045893	positive regulation of transcription, DNA-templated

0.64	GO:0000993	RNA polymerase II core binding
0.55	GO:0003677	DNA binding
0.44	GO:0046872	metal ion binding
0.37	GO:0003723	RNA binding

0.68	GO:0044609	DBIRD complex
0.61	GO:0005634	nucleus
0.53	GO:0031974	membrane-enclosed lumen
0.49	GO:0030529	intracellular ribonucleoprotein complex
0.48	GO:0044446	intracellular organelle part

sp|O88307|SORL_MOUSE
Sortilin-related receptor
Search

SORL1

0.96	Sortilin-related receptor, L(DLR class) A repeats containing

0.69	GO:0005794	Golgi apparatus
0.30	GO:0044425	membrane part

sp|O88310|ITL1A_MOUSE
Intelectin-1a
Search

ITLN1

0.97	Intelectin 1 (Galactofuranose binding)

0.69	GO:0070207	protein homotrimerization
0.69	GO:0046326	positive regulation of glucose import
0.62	GO:0001934	positive regulation of protein phosphorylation
0.58	GO:0009624	response to nematode
0.50	GO:0019730	antimicrobial humoral response
0.45	GO:0006952	defense response
0.45	GO:0009617	response to bacterium
0.40	GO:0034214	protein hexamerization

0.69	GO:0070492	oligosaccharide binding
0.59	GO:0042802	identical protein binding
0.58	GO:0005509	calcium ion binding
0.43	GO:0005537	mannose binding
0.41	GO:2001065	mannan binding
0.38	GO:0001530	lipopolysaccharide binding
0.37	GO:0008061	chitin binding

0.62	GO:0043235	receptor complex
0.55	GO:0031526	brush border membrane
0.52	GO:0045121	membrane raft
0.50	GO:0005576	extracellular region
0.47	GO:0031225	anchored component of membrane
0.45	GO:0031982	vesicle
0.36	GO:0012505	endomembrane system
0.34	GO:0005737	cytoplasm
0.34	GO:0043229	intracellular organelle
0.30	GO:0016021	integral component of membrane

sp|O88312|AGR2_MOUSE
Anterior gradient protein 2 homolog
Search

AGR2

0.97	Anterior gradient protein 2

0.80	GO:0070254	mucus secretion
0.79	GO:0060480	lung goblet cell differentiation
0.78	GO:1903896	positive regulation of IRE1-mediated unfolded protein response
0.77	GO:1903899	positive regulation of PERK-mediated unfolded protein response
0.74	GO:0048565	digestive tract development
0.74	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
0.73	GO:0010811	positive regulation of cell-substrate adhesion
0.72	GO:1903078	positive regulation of protein localization to plasma membrane
0.70	GO:0048639	positive regulation of developmental growth
0.69	GO:0060548	negative regulation of cell death

0.80	GO:0002162	dystroglycan binding
0.73	GO:0005154	epidermal growth factor receptor binding
0.65	GO:0042803	protein homodimerization activity

0.65	GO:0005783	endoplasmic reticulum
0.62	GO:0005615	extracellular space
0.53	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

sp|O88319|NTR1_MOUSE
Neurotensin receptor type 1
Search

NTSR1

0.96	Neurotensin receptor type 1

0.79	GO:0007218	neuropeptide signaling pathway
0.64	GO:0008344	adult locomotory behavior
0.60	GO:0043066	negative regulation of apoptotic process
0.46	GO:0014054	positive regulation of gamma-aminobutyric acid secretion
0.46	GO:0097151	positive regulation of inhibitory postsynaptic potential
0.46	GO:0090238	positive regulation of arachidonic acid secretion
0.46	GO:0014049	positive regulation of glutamate secretion
0.46	GO:0070777	D-aspartate transport
0.46	GO:0098712	L-glutamate import across plasma membrane
0.46	GO:0060732	positive regulation of inositol phosphate biosynthetic process

0.86	GO:0016492	G-protein coupled neurotensin receptor activity
0.58	GO:0042802	identical protein binding
0.44	GO:0047485	protein N-terminus binding
0.41	GO:0046982	protein heterodimerization activity

0.62	GO:0098857	membrane microdomain
0.53	GO:0005887	integral component of plasma membrane
0.47	GO:0032280	symmetric synapse
0.45	GO:0043198	dendritic shaft
0.44	GO:0043204	perikaryon
0.44	GO:0043195	terminal bouton
0.44	GO:0043197	dendritic spine
0.42	GO:0009898	cytoplasmic side of plasma membrane
0.42	GO:0009986	cell surface
0.41	GO:0005794	Golgi apparatus

sp|O88322|NID2_MOUSE
Nidogen-2
Search

NID2

0.60	Nidogen 2a (osteonidogen)

0.78	GO:0007160	cell-matrix adhesion
0.47	GO:0032836	glomerular basement membrane development
0.45	GO:0010811	positive regulation of cell-substrate adhesion
0.33	GO:0071711	basement membrane organization
0.32	GO:0006508	proteolysis

0.69	GO:0005509	calcium ion binding
0.47	GO:0043237	laminin-1 binding
0.46	GO:0043394	proteoglycan binding
0.45	GO:0005518	collagen binding
0.32	GO:0004222	metalloendopeptidase activity
0.32	GO:0008270	zinc ion binding

0.57	GO:0005604	basement membrane
0.48	GO:0005615	extracellular space
0.43	GO:0071944	cell periphery
0.33	GO:1903561	extracellular vesicle
0.32	GO:0009986	cell surface
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0004222

sp|O88324|CD83_MOUSE
CD83 antigen
Search

tr|O88325|O88325_MOUSE
Alpha-N-acetylglucosaminidase
Search

NAGLU

0.71	Lysosomal alpha-N-acetyl glucosaminidase

0.84	GO:0046548	retinal rod cell development
0.83	GO:0042474	middle ear morphogenesis
0.81	GO:0021680	cerebellar Purkinje cell layer development
0.81	GO:0045475	locomotor rhythm
0.80	GO:0060119	inner ear receptor cell development
0.78	GO:0007040	lysosome organization
0.40	GO:0015991	ATP hydrolysis coupled proton transport
0.38	GO:0006027	glycosaminoglycan catabolic process
0.37	GO:0016573	histone acetylation
0.35	GO:0006511	ubiquitin-dependent protein catabolic process

0.47	GO:0004561	alpha-N-acetylglucosaminidase activity
0.38	GO:0004402	histone acetyltransferase activity
0.37	GO:0015078	hydrogen ion transmembrane transporter activity
0.36	GO:0030151	molybdenum ion binding
0.36	GO:0070003	threonine-type peptidase activity
0.35	GO:0030170	pyridoxal phosphate binding
0.34	GO:0004175	endopeptidase activity

0.76	GO:0070062	extracellular exosome
0.41	GO:0043202	lysosomal lumen
0.40	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.36	GO:0019773	proteasome core complex, alpha-subunit complex
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.47

EC:3.2.1.50

GO:0004561

sp|O88327|CTNL1_MOUSE
Alpha-catulin
Search

CTNNAL1

0.89	Alpha-catulin

0.85	GO:0007266	Rho protein signal transduction
0.72	GO:0007155	cell adhesion

0.78	GO:0051015	actin filament binding
0.69	GO:0045296	cadherin binding

0.49	GO:0005829	cytosol
0.36	GO:0005856	cytoskeleton
0.35	GO:0005938	cell cortex
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|O88329|MYO1A_MOUSE
Unconventional myosin-Ia
Search

MYO1A

0.91	LOW QUALITY PROTEIN: unconventional myosin-Ia

0.74	GO:0007018	microtubule-based movement
0.56	GO:0030033	microvillus assembly
0.52	GO:0007605	sensory perception of sound
0.52	GO:0051648	vesicle localization
0.48	GO:0006892	post-Golgi vesicle-mediated transport
0.47	GO:0007015	actin filament organization
0.45	GO:0030048	actin filament-based movement
0.39	GO:0007217	tachykinin receptor signaling pathway
0.36	GO:0033572	transferrin transport
0.35	GO:0045056	transcytosis

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.74	GO:0003779	actin binding
0.55	GO:0032403	protein complex binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0000146	microfilament motor activity
0.48	GO:0045296	cadherin binding
0.45	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding

0.77	GO:0016459	myosin complex
0.59	GO:0005884	actin filament
0.57	GO:0005903	brush border
0.57	GO:0098858	actin-based cell projection
0.55	GO:0009925	basal plasma membrane
0.55	GO:0016328	lateral plasma membrane
0.53	GO:0044853	plasma membrane raft
0.53	GO:0045177	apical part of cell
0.52	GO:0030864	cortical actin cytoskeleton
0.50	GO:0032588	trans-Golgi network membrane

sp|O88335|KCNJ1_MOUSE
ATP-sensitive inward rectifier potassium channel 1
Search

KCNJ1

0.97	LOW QUALITY PROTEIN: ATP-sensitive inward rectifier potassium channel 1

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.42	GO:0098660	inorganic ion transmembrane transport
0.38	GO:0070294	renal sodium ion absorption
0.37	GO:0043266	regulation of potassium ion transport
0.37	GO:0001894	tissue homeostasis
0.37	GO:0022898	regulation of transmembrane transporter activity
0.37	GO:0001822	kidney development
0.36	GO:0072358	cardiovascular system development

0.84	GO:0005242	inward rectifier potassium channel activity
0.56	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.35	GO:0042277	peptide binding
0.34	GO:0030955	potassium ion binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005887	integral component of plasma membrane
0.34	GO:0034705	potassium channel complex

sp|O88338|CAD16_MOUSE
Cadherin-16
Search

CDH16

0.95	Cadherin-16 isoform B

0.78	GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules
0.43	GO:0007267	cell-cell signaling
0.43	GO:0007399	nervous system development
0.35	GO:0007165	signal transduction
0.33	GO:0002576	platelet degranulation
0.32	GO:0009409	response to cold
0.32	GO:0050808	synapse organization
0.32	GO:0022607	cellular component assembly

0.70	GO:0005509	calcium ion binding
0.36	GO:0003924	GTPase activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0005515	protein binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0016323	basolateral plasma membrane
0.42	GO:0005887	integral component of plasma membrane
0.33	GO:0031092	platelet alpha granule membrane
0.33	GO:0043083	synaptic cleft
0.33	GO:0043679	axon terminus
0.32	GO:0070062	extracellular exosome

sp|O88342|WDR1_MOUSE
WD repeat-containing protein 1
Search

WDR1

0.96	WD repeat-containing protein 1

0.84	GO:0030043	actin filament fragmentation
0.84	GO:0042247	establishment of planar polarity of follicular epithelium
0.82	GO:0045199	maintenance of epithelial cell apical/basal polarity
0.81	GO:0030836	positive regulation of actin filament depolymerization
0.80	GO:0045214	sarcomere organization
0.79	GO:0030220	platelet formation
0.79	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization
0.78	GO:0043297	apical junction assembly
0.78	GO:0002446	neutrophil mediated immunity
0.76	GO:1990266	neutrophil migration

0.59	GO:0051015	actin filament binding
0.34	GO:0022857	transmembrane transporter activity
0.30	GO:0003824	catalytic activity

0.73	GO:0043209	myelin sheath
0.70	GO:0005911	cell-cell junction
0.66	GO:0042643	actomyosin, actin portion
0.59	GO:0030864	cortical actin cytoskeleton
0.53	GO:0005886	plasma membrane
0.48	GO:0002102	podosome
0.42	GO:0042995	cell projection
0.42	GO:0070062	extracellular exosome
0.38	GO:0005634	nucleus
0.36	GO:0005829	cytosol

sp|O88343|S4A4_MOUSE
Electrogenic sodium bicarbonate cotransporter 1
Search

SLC4A4

0.62	Anion exchange protein (Fragment)

0.69	GO:0098656	anion transmembrane transport
0.69	GO:0015698	inorganic anion transport
0.59	GO:0015701	bicarbonate transport
0.53	GO:0035725	sodium ion transmembrane transport
0.45	GO:0051453	regulation of intracellular pH

0.83	GO:0005452	inorganic anion exchanger activity
0.61	GO:0008510	sodium:bicarbonate symporter activity

0.52	GO:0016323	basolateral plasma membrane
0.40	GO:0005887	integral component of plasma membrane

sp|O88346|TNNT1_MOUSE
Troponin T, slow skeletal muscle
Search

TNNT1

0.96	Nemaline myopathy mutant slow skeletal muscle troponin T high molecular weight variant

0.81	GO:0006937	regulation of muscle contraction
0.53	GO:0006941	striated muscle contraction
0.52	GO:0014883	transition between fast and slow fiber
0.50	GO:0050881	musculoskeletal movement
0.47	GO:0051241	negative regulation of multicellular organismal process
0.45	GO:0030049	muscle filament sliding
0.45	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.44	GO:0008016	regulation of heart contraction
0.43	GO:0060047	heart contraction
0.42	GO:0051592	response to calcium ion

0.53	GO:0005523	tropomyosin binding
0.44	GO:0030172	troponin C binding
0.44	GO:0031013	troponin I binding
0.40	GO:0031014	troponin T binding
0.40	GO:0003779	actin binding
0.34	GO:0030674	protein binding, bridging
0.33	GO:0016887	ATPase activity

0.82	GO:0005861	troponin complex
0.41	GO:0097512	cardiac myofibril
0.35	GO:0005829	cytosol

0.33

GO:0016887

sp|O88351|IKKB_MOUSE
Inhibitor of nuclear factor kappa-B kinase subunit beta
Search

IKBKB

0.96	Inhibitor of nuclear factor kappa-B kinase subunit beta

0.79	GO:0007252	I-kappaB phosphorylation
0.62	GO:1903347	negative regulation of bicellular tight junction assembly
0.62	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity
0.61	GO:1903140	regulation of establishment of endothelial barrier
0.60	GO:0070498	interleukin-1-mediated signaling pathway
0.60	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.58	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.57	GO:0018105	peptidyl-serine phosphorylation
0.57	GO:0072659	protein localization to plasma membrane
0.57	GO:0030866	cortical actin cytoskeleton organization

0.81	GO:0008384	IkappaB kinase activity
0.59	GO:0097110	scaffold protein binding
0.55	GO:0019901	protein kinase binding
0.53	GO:0042803	protein homodimerization activity
0.53	GO:0030554	adenyl nucleotide binding
0.53	GO:0046982	protein heterodimerization activity
0.52	GO:0032555	purine ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity

0.51	GO:0005829	cytosol
0.46	GO:1902554	serine/threonine protein kinase complex
0.40	GO:0035631	CD40 receptor complex
0.40	GO:0098857	membrane microdomain
0.38	GO:0009898	cytoplasmic side of plasma membrane
0.37	GO:0005634	nucleus
0.33	GO:0005783	endoplasmic reticulum
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part

0.81

EC:2.7.11.10

GO:0008384

tr|O88375|O88375_MOUSE
Keratin associated protein 13
Search

0.92	Keratin-associated protein 13

0.51

GO:0031424

keratinization

0.37

GO:0005515

protein binding

0.62	GO:0005882	intermediate filament
0.44	GO:0005829	cytosol

sp|O88379|BAZ1A_MOUSE
Bromodomain adjacent to zinc finger domain protein 1A
Search

BAZ1A

0.91	LOW QUALITY PROTEIN: bromodomain adjacent to zinc finger domain protein 1A

0.72	GO:0006338	chromatin remodeling
0.51	GO:0006261	DNA-dependent DNA replication
0.41	GO:0030042	actin filament depolymerization
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.53	GO:0046872	metal ion binding
0.39	GO:0003779	actin binding
0.36	GO:0004402	histone acetyltransferase activity

0.62	GO:0008623	CHRAC
0.39	GO:0015629	actin cytoskeleton
0.38	GO:0016590	ACF complex

0.36

EC:2.3.1.48

GO:0004402

sp|O88384|VTI1B_MOUSE
Vesicle transport through interaction with t-SNAREs homolog 1B
Search

VTI1B

0.97	Vesicle transport through interaction with t-SNAREs like protein 1B

0.68	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.48	GO:0072666	establishment of protein localization to vacuole
0.48	GO:1903076	regulation of protein localization to plasma membrane
0.48	GO:0090174	organelle membrane fusion
0.47	GO:0016482	cytosolic transport
0.47	GO:0016050	vesicle organization
0.47	GO:0007034	vacuolar transport
0.47	GO:0016197	endosomal transport
0.42	GO:0065009	regulation of molecular function

0.54	GO:0005484	SNAP receptor activity
0.52	GO:0000149	SNARE binding
0.50	GO:0019869	chloride channel inhibitor activity
0.36	GO:0052650	NADP-retinol dehydrogenase activity
0.33	GO:0015631	tubulin binding
0.32	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.53	GO:0031902	late endosome membrane
0.52	GO:0005794	Golgi apparatus
0.49	GO:0055038	recycling endosome membrane
0.49	GO:0031901	early endosome membrane
0.48	GO:0031201	SNARE complex
0.48	GO:0005765	lysosomal membrane
0.47	GO:0012507	ER to Golgi transport vesicle membrane
0.47	GO:0005829	cytosol
0.46	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0005789	endoplasmic reticulum membrane

0.36	EC:1.1.1.300	GO:0052650
0.36	KEGG:R08379	GO:0052650

sp|O88393|TGBR3_MOUSE
Transforming growth factor beta receptor type 3
Search

TGFBR3

0.96	Transforming growth factor beta receptor type 3

0.64	GO:0034699	response to luteinizing hormone
0.63	GO:0032354	response to follicle-stimulating hormone
0.62	GO:0060317	cardiac epithelial to mesenchymal transition
0.61	GO:0060389	pathway-restricted SMAD protein phosphorylation
0.61	GO:0034695	response to prostaglandin E
0.59	GO:0030509	BMP signaling pathway
0.58	GO:0007179	transforming growth factor beta receptor signaling pathway
0.58	GO:0051271	negative regulation of cellular component movement
0.53	GO:0006955	immune response
0.47	GO:0035556	intracellular signal transduction

0.67	GO:0070123	transforming growth factor beta receptor activity, type III
0.63	GO:0050431	transforming growth factor beta binding
0.62	GO:0005114	type II transforming growth factor beta receptor binding
0.60	GO:0015026	coreceptor activity
0.59	GO:0046332	SMAD binding
0.45	GO:0005539	glycosaminoglycan binding
0.42	GO:0048185	activin binding
0.41	GO:0017134	fibroblast growth factor binding
0.40	GO:0030165	PDZ domain binding
0.39	GO:1901681	sulfur compound binding

0.63	GO:0034673	inhibin-betaglycan-ActRII complex
0.63	GO:0005576	extracellular region
0.58	GO:0009897	external side of plasma membrane
0.55	GO:0043235	receptor complex
0.41	GO:0005887	integral component of plasma membrane
0.38	GO:0005622	intracellular
0.36	GO:0031982	vesicle
0.36	GO:0012505	endomembrane system

sp|O88396|GRPE2_MOUSE
GrpE protein homolog 2, mitochondrial
Search

GRPEL2

0.67	GrpE protein like protein 2, mitochondrial

0.69	GO:0006457	protein folding
0.69	GO:0050790	regulation of catalytic activity
0.49	GO:0030150	protein import into mitochondrial matrix
0.35	GO:0030329	prenylcysteine metabolic process
0.35	GO:0000098	sulfur amino acid catabolic process
0.34	GO:0042219	cellular modified amino acid catabolic process
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0055114	oxidation-reduction process
0.32	GO:0010467	gene expression

0.79	GO:0000774	adenyl-nucleotide exchange factor activity
0.77	GO:0051087	chaperone binding
0.75	GO:0042803	protein homodimerization activity
0.52	GO:0051082	unfolded protein binding
0.35	GO:0001735	prenylcysteine oxidase activity
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0016746	transferase activity, transferring acyl groups

0.65	GO:0005759	mitochondrial matrix
0.51	GO:0001405	presequence translocase-associated import motor
0.34	GO:0005634	nucleus
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.35

EC:1.8.3.5

GO:0001735

sp|O88398|AVIL_MOUSE
Advillin
Search

AVIL

0.95

Advillin

0.69	GO:0007010	cytoskeleton organization
0.63	GO:0051014	actin filament severing
0.63	GO:0051130	positive regulation of cellular component organization
0.63	GO:0051693	actin filament capping
0.59	GO:0044089	positive regulation of cellular component biogenesis
0.58	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.57	GO:0097435	supramolecular fiber organization
0.56	GO:0051240	positive regulation of multicellular organismal process
0.56	GO:0051094	positive regulation of developmental process
0.53	GO:0030154	cell differentiation

0.78	GO:0051015	actin filament binding
0.64	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.54	GO:0005509	calcium ion binding
0.51	GO:0035727	lysophosphatidic acid binding
0.49	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.45	GO:0042803	protein homodimerization activity

0.50	GO:0032433	filopodium tip
0.48	GO:0005902	microvillus
0.48	GO:0032432	actin filament bundle
0.48	GO:0001726	ruffle
0.47	GO:0030027	lamellipodium
0.47	GO:0005903	brush border
0.38	GO:0005886	plasma membrane
0.38	GO:0030424	axon
0.34	GO:0070062	extracellular exosome
0.34	GO:0005737	cytoplasm

sp|O88410|CXCR3_MOUSE
C-X-C chemokine receptor type 3
Search

CXCR3

0.96	LOW QUALITY PROTEIN: C-X-C chemokine receptor type 3

0.80	GO:0070098	chemokine-mediated signaling pathway
0.72	GO:0002685	regulation of leukocyte migration
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.70	GO:0006954	inflammatory response
0.68	GO:0006935	chemotaxis
0.46	GO:0071954	chemokine (C-C motif) ligand 11 production
0.45	GO:0002376	immune system process
0.44	GO:1900118	negative regulation of execution phase of apoptosis
0.44	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.43	GO:0050921	positive regulation of chemotaxis

0.81	GO:0004950	chemokine receptor activity
0.60	GO:0019956	chemokine binding
0.41	GO:0005044	scavenger receptor activity
0.36	GO:0004875	complement receptor activity
0.36	GO:0001847	opsonin receptor activity
0.35	GO:0015026	coreceptor activity
0.34	GO:0016907	G-protein coupled acetylcholine receptor activity
0.33	GO:0008188	neuropeptide receptor activity
0.32	GO:0042277	peptide binding

0.52	GO:0009897	external side of plasma membrane
0.38	GO:0005887	integral component of plasma membrane
0.35	GO:0005884	actin filament
0.35	GO:0031965	nuclear membrane
0.34	GO:0005654	nucleoplasm
0.34	GO:0005829	cytosol
0.34	GO:0009925	basal plasma membrane
0.33	GO:0045177	apical part of cell
0.32	GO:0045211	postsynaptic membrane
0.32	GO:0030054	cell junction

sp|O88413|TULP3_MOUSE
Tubby-related protein 3
Search

TULP3

0.86	Tubby like protein 3

0.78	GO:0060434	bronchus morphogenesis
0.78	GO:0097500	receptor localization to non-motile cilium
0.78	GO:0043010	camera-type eye development
0.78	GO:1903546	protein localization to photoreceptor outer segment
0.77	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
0.77	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.76	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.75	GO:0048702	embryonic neurocranium morphogenesis
0.75	GO:0061548	ganglion development
0.72	GO:0042733	embryonic digit morphogenesis

0.72	GO:0032403	protein complex binding
0.69	GO:0035091	phosphatidylinositol binding
0.61	GO:0019899	enzyme binding
0.40	GO:0003700	DNA binding transcription factor activity

0.74	GO:0097546	ciliary base
0.73	GO:0030991	intraciliary transport particle A
0.69	GO:0005930	axoneme
0.63	GO:0005730	nucleolus
0.52	GO:0005576	extracellular region
0.52	GO:0005829	cytosol
0.50	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|O88416|GPR33_MOUSE
Probable G-protein coupled receptor 33
Search

GPR33

0.80	G protein-coupled receptor 33 variant 1

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.58	GO:0002430	complement receptor mediated signaling pathway
0.52	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.51	GO:0050900	leukocyte migration
0.50	GO:0006954	inflammatory response
0.50	GO:0060326	cell chemotaxis
0.44	GO:0010759	positive regulation of macrophage chemotaxis
0.44	GO:0090023	positive regulation of neutrophil chemotaxis
0.44	GO:0010575	positive regulation of vascular endothelial growth factor production
0.43	GO:0045766	positive regulation of angiogenesis

0.72	GO:0004930	G-protein coupled receptor activity
0.59	GO:0004875	complement receptor activity
0.41	GO:0001653	peptide receptor activity
0.38	GO:0001614	purinergic nucleotide receptor activity
0.37	GO:0019957	C-C chemokine binding
0.36	GO:0004896	cytokine receptor activity
0.36	GO:0005044	scavenger receptor activity
0.36	GO:0042923	neuropeptide binding
0.35	GO:0001847	opsonin receptor activity
0.34	GO:0009881	photoreceptor activity

0.45	GO:0005887	integral component of plasma membrane
0.35	GO:0005654	nucleoplasm
0.35	GO:0043005	neuron projection
0.35	GO:0016323	basolateral plasma membrane
0.35	GO:0016324	apical plasma membrane
0.34	GO:0035579	specific granule membrane
0.34	GO:0035577	azurophil granule membrane
0.33	GO:0005884	actin filament
0.33	GO:0031965	nuclear membrane
0.32	GO:0097731	9+0 non-motile cilium

sp|O88425|NDK6_MOUSE
Nucleoside diphosphate kinase 6
Search

NME6

0.45	Nucleoside diphosphate kinase

0.77	GO:0006228	UTP biosynthetic process
0.77	GO:0006183	GTP biosynthetic process
0.74	GO:0046036	CTP metabolic process
0.69	GO:0006165	nucleoside diphosphate phosphorylation
0.39	GO:0030308	negative regulation of cell growth
0.39	GO:0045839	negative regulation of mitotic nuclear division
0.36	GO:0015949	nucleobase-containing small molecule interconversion
0.35	GO:0006915	apoptotic process
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.78	GO:0004550	nucleoside diphosphate kinase activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0046872	metal ion binding
0.33	GO:0004519	endonuclease activity

0.45	GO:0005739	mitochondrion
0.34	GO:0005829	cytosol

0.78

EC:2.7.4.6

GO:0004550

sp|O88427|CAC1H_MOUSE
Voltage-dependent T-type calcium channel subunit alpha-1H
Search

CACNA1H

0.75	Voltage-dependent T-type calcium channel subunit alpha

0.75	GO:0070588	calcium ion transmembrane transport
0.67	GO:0070509	calcium ion import
0.66	GO:0019228	neuronal action potential
0.59	GO:0030317	flagellated sperm motility
0.56	GO:0034651	cortisol biosynthetic process
0.56	GO:0032341	aldosterone metabolic process
0.56	GO:0051049	regulation of transport
0.56	GO:0006705	mineralocorticoid biosynthetic process
0.54	GO:2000344	positive regulation of acrosome reaction
0.54	GO:0006700	C21-steroid hormone biosynthetic process

0.80	GO:0005245	voltage-gated calcium channel activity
0.53	GO:0097110	scaffold protein binding
0.51	GO:0005248	voltage-gated sodium channel activity
0.35	GO:0046872	metal ion binding

0.79	GO:0005891	voltage-gated calcium channel complex
0.45	GO:0005887	integral component of plasma membrane
0.39	GO:0042383	sarcolemma
0.39	GO:0005901	caveola
0.37	GO:0043204	perikaryon
0.36	GO:0030425	dendrite
0.34	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm

sp|O88428|PAPS2_MOUSE
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2
Search

PAPSS2

0.97	LOW QUALITY PROTEIN: bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2

0.76	GO:0000103	sulfate assimilation
0.57	GO:0016310	phosphorylation
0.52	GO:0060348	bone development
0.51	GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process
0.51	GO:0007596	blood coagulation
0.34	GO:0070814	hydrogen sulfide biosynthetic process

0.80	GO:0004020	adenylylsulfate kinase activity
0.79	GO:0004781	sulfate adenylyltransferase (ATP) activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0098616	selenate adenylyltransferase (ATP) activity
0.34	GO:0042803	protein homodimerization activity

0.35

GO:0005829

cytosol

0.80

EC:2.7.1.25

GO:0004020

sp|O88430|CCL22_MOUSE
C-C motif chemokine 22
Search

CCL22

0.65	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.79	GO:0006954	inflammatory response
0.74	GO:0006955	immune response
0.72	GO:0010469	regulation of receptor activity
0.59	GO:0071674	mononuclear cell migration
0.58	GO:0072676	lymphocyte migration
0.58	GO:1990266	neutrophil migration
0.57	GO:0071347	cellular response to interleukin-1
0.56	GO:0071356	cellular response to tumor necrosis factor
0.56	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.84	GO:0008009	chemokine activity
0.59	GO:0048020	CCR chemokine receptor binding

0.73	GO:0005615	extracellular space
0.30	GO:0016020	membrane

sp|O88441|MTX2_MOUSE
Metaxin-2
Search

MTX2

0.87	Metaxin-2 protein 2

0.78

GO:0006626

protein targeting to mitochondrion

0.33	GO:0005515	protein binding
0.32	GO:0003723	RNA binding

0.77	GO:0005741	mitochondrial outer membrane
0.50	GO:0005730	nucleolus
0.30	GO:0016021	integral component of membrane

sp|O88444|ADCY1_MOUSE
Adenylate cyclase type 1
Search

ADCY1

0.77	Adenylate cyclase type 1

0.74	GO:0006171	cAMP biosynthetic process
0.62	GO:0035556	intracellular signal transduction
0.53	GO:0007616	long-term memory
0.53	GO:0007409	axonogenesis
0.53	GO:0042752	regulation of circadian rhythm
0.48	GO:0006182	cGMP biosynthetic process
0.41	GO:0008038	neuron recognition
0.41	GO:0007605	sensory perception of sound
0.40	GO:0097485	neuron projection guidance
0.40	GO:1904321	response to forskolin

0.74	GO:0004016	adenylate cyclase activity
0.52	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.48	GO:0004383	guanylate cyclase activity
0.47	GO:0097367	carbohydrate derivative binding
0.47	GO:0008144	drug binding
0.46	GO:0043168	anion binding
0.38	GO:0005516	calmodulin binding
0.34	GO:0046872	metal ion binding

0.53	GO:0005886	plasma membrane
0.49	GO:0008074	guanylate cyclase complex, soluble
0.38	GO:0045121	membrane raft
0.37	GO:0070062	extracellular exosome
0.35	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.74

EC:4.6.1.1

GO:0004016

sp|O88445|AURKC_MOUSE
Aurora kinase C
Search

AURKB

0.96	Aurora kinase C

0.70	GO:0035404	histone-serine phosphorylation
0.69	GO:0007051	spindle organization
0.64	GO:0000278	mitotic cell cycle
0.62	GO:0051321	meiotic cell cycle
0.62	GO:0032465	regulation of cytokinesis
0.61	GO:0051781	positive regulation of cell division
0.60	GO:0007292	female gamete generation
0.60	GO:0090068	positive regulation of cell cycle process
0.60	GO:0031577	spindle checkpoint
0.59	GO:0022412	cellular process involved in reproduction in multicellular organism

0.69	GO:0004674	protein serine/threonine kinase activity
0.61	GO:0035173	histone kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.51	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.51	GO:0019900	kinase binding
0.44	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0046982	protein heterodimerization activity

0.77	GO:0032133	chromosome passenger complex
0.60	GO:0051233	spindle midzone
0.58	GO:0031616	spindle pole centrosome
0.56	GO:0000793	condensed chromosome
0.56	GO:0030496	midbody
0.55	GO:0005876	spindle microtubule
0.53	GO:0000775	chromosome, centromeric region
0.52	GO:0072686	mitotic spindle
0.51	GO:0044454	nuclear chromosome part
0.49	GO:0042585	germinal vesicle

0.69

GO:0004674

sp|O88447|KLC1_MOUSE
Kinesin light chain 1
Search

KLC1

0.89	Kinesin light chain 1

0.46	GO:0097193	intrinsic apoptotic signaling pathway
0.40	GO:0035617	stress granule disassembly
0.38	GO:0035418	protein localization to synapse
0.38	GO:0008088	axo-dendritic transport
0.36	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0006886	intracellular protein transport
0.35	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.33	GO:0016032	viral process

0.73	GO:0003777	microtubule motor activity
0.36	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.80	GO:0005871	kinesin complex
0.41	GO:0030426	growth cone
0.39	GO:0031982	vesicle
0.38	GO:0030424	axon
0.38	GO:0005874	microtubule
0.38	GO:0035253	ciliary rootlet
0.37	GO:0043025	neuronal cell body
0.36	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|O88448|KLC2_MOUSE
Kinesin light chain 2
Search

KLC2

0.87	Kinesin light chain 2

0.43	GO:0036269	swimming behavior
0.41	GO:0097193	intrinsic apoptotic signaling pathway
0.37	GO:0008088	axo-dendritic transport
0.36	GO:0035418	protein localization to synapse
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0016192	vesicle-mediated transport
0.34	GO:0006886	intracellular protein transport

0.75	GO:0003777	microtubule motor activity
0.53	GO:0045296	cadherin binding
0.39	GO:0019894	kinesin binding
0.35	GO:0003924	GTPase activity
0.35	GO:0015631	tubulin binding
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.81	GO:0005871	kinesin complex
0.48	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol
0.44	GO:0005739	mitochondrion
0.42	GO:0005886	plasma membrane
0.38	GO:0043005	neuron projection
0.38	GO:0120038	plasma membrane bounded cell projection part
0.36	GO:0005874	microtubule
0.36	GO:0030427	site of polarized growth
0.36	GO:0005929	cilium

sp|O88451|RDH7_MOUSE
Retinol dehydrogenase 7
Search

0.94	Retinol dehydrogenase similar protein 2

0.51	GO:0055114	oxidation-reduction process
0.48	GO:0001523	retinoid metabolic process
0.43	GO:0034754	cellular hormone metabolic process
0.43	GO:0016102	diterpenoid biosynthetic process
0.43	GO:0008202	steroid metabolic process
0.38	GO:0072330	monocarboxylic acid biosynthetic process
0.38	GO:0034308	primary alcohol metabolic process
0.36	GO:0017144	drug metabolic process
0.34	GO:0042446	hormone biosynthetic process
0.34	GO:0042447	hormone catabolic process

0.56	GO:0004745	retinol dehydrogenase activity
0.44	GO:0016229	steroid dehydrogenase activity
0.37	GO:0042803	protein homodimerization activity
0.34	GO:0009055	electron transfer activity

0.41	GO:0005783	endoplasmic reticulum
0.37	GO:0031090	organelle membrane
0.37	GO:0044446	intracellular organelle part
0.37	GO:0043233	organelle lumen
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0005769	early endosome
0.35	GO:0098805	whole membrane
0.34	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.33	GO:0043232	intracellular non-membrane-bounded organelle

0.56

EC:1.1.1.105

GO:0004745

sp|O88452|STC2_MOUSE
Stanniocalcin-2
Search

STC2

0.97	Stanniocalcin 2

0.76	GO:0010469	regulation of receptor activity
0.60	GO:0046885	regulation of hormone biosynthetic process
0.57	GO:0040015	negative regulation of multicellular organism growth
0.56	GO:2001256	regulation of store-operated calcium entry
0.55	GO:0030968	endoplasmic reticulum unfolded protein response
0.53	GO:0006874	cellular calcium ion homeostasis
0.50	GO:0010629	negative regulation of gene expression
0.49	GO:0006979	response to oxidative stress
0.43	GO:0046697	decidualization
0.42	GO:0033280	response to vitamin D

0.79	GO:0005179	hormone activity
0.54	GO:0042803	protein homodimerization activity
0.52	GO:0019899	enzyme binding
0.47	GO:0020037	heme binding
0.33	GO:0043565	sequence-specific DNA binding

0.66	GO:0005576	extracellular region
0.56	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005783	endoplasmic reticulum
0.49	GO:0005794	Golgi apparatus
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005634	nucleus

sp|O88454|KCNK4_MOUSE
Potassium channel subfamily K member 4
Search

KCNK4

0.94	Potassium two pore domain channel subfamily K member 4

0.73	GO:0071805	potassium ion transmembrane transport
0.60	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch
0.58	GO:0050951	sensory perception of temperature stimulus
0.58	GO:0071398	cellular response to fatty acid
0.58	GO:0019233	sensory perception of pain
0.57	GO:0071260	cellular response to mechanical stimulus
0.51	GO:0030322	stabilization of membrane potential
0.45	GO:0071502	cellular response to temperature stimulus
0.44	GO:0071469	cellular response to alkaline pH
0.43	GO:0007613	memory

0.76	GO:0005267	potassium channel activity
0.53	GO:0140135	mechanosensitive cation channel activity
0.51	GO:0022842	narrow pore channel activity
0.45	GO:0097603	temperature-gated ion channel activity
0.39	GO:0022832	voltage-gated channel activity
0.38	GO:0042802	identical protein binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.53	GO:0034705	potassium channel complex
0.50	GO:0005887	integral component of plasma membrane
0.31	GO:0005634	nucleus

sp|O88455|DHCR7_MOUSE
7-dehydrocholesterol reductase
Search

DHCR7

0.93	7-dehydrocholesterol reductase large variant

0.58	GO:0006695	cholesterol biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.51	GO:0035264	multicellular organism growth
0.51	GO:0030324	lung development
0.50	GO:0016132	brassinosteroid biosynthetic process
0.49	GO:0001568	blood vessel development
0.49	GO:0009791	post-embryonic development
0.48	GO:0042127	regulation of cell proliferation
0.46	GO:0030154	cell differentiation
0.40	GO:0045540	regulation of cholesterol biosynthetic process

0.73	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
0.51	GO:0009918	sterol delta7 reductase activity
0.39	GO:0050661	NADP binding

0.55	GO:0005640	nuclear outer membrane
0.50	GO:0005783	endoplasmic reticulum
0.47	GO:0005829	cytosol
0.43	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.73

EC:1.3.1

GO:0016628

sp|O88456|CPNS1_MOUSE
Calpain small subunit 1
Search

CAPNS1

0.97	Calpain small subunit 1

0.45	GO:0006508	proteolysis
0.38	GO:0022617	extracellular matrix disassembly
0.36	GO:0070268	cornification
0.36	GO:0016241	regulation of macroautophagy
0.35	GO:0008284	positive regulation of cell proliferation

0.68	GO:0005509	calcium ion binding
0.56	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.36	GO:0005515	protein binding

0.48	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.37	GO:0005886	plasma membrane

sp|O88466|ZN106_MOUSE
Zinc finger protein 106
Search

ZNF106

0.96	Zinc finger protein 106 homolog

0.51	GO:0008286	insulin receptor signaling pathway
0.36	GO:0010469	regulation of receptor activity

0.50	GO:0003676	nucleic acid binding
0.48	GO:0017124	SH3 domain binding
0.38	GO:0001515	opioid peptide activity
0.38	GO:0008270	zinc ion binding

0.44	GO:0005829	cytosol
0.38	GO:0005730	nucleolus
0.30	GO:0016020	membrane

sp|O88470|FOXL2_MOUSE
Forkhead box protein L2
Search

FOXL2

0.79	Forkhead transcription factor Foxl2

0.63	GO:0002074	extraocular skeletal muscle development
0.61	GO:0019101	female somatic sex determination
0.60	GO:0006309	apoptotic DNA fragmentation
0.60	GO:0001541	ovarian follicle development
0.59	GO:0060014	granulosa cell differentiation
0.58	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.57	GO:0046881	positive regulation of follicle-stimulating hormone secretion
0.57	GO:0033686	positive regulation of luteinizing hormone secretion
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process
0.55	GO:0031624	ubiquitin conjugating enzyme binding
0.55	GO:0030331	estrogen receptor binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.55	GO:0045171	intercellular bridge
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part

sp|O88472|TNR17_MOUSE
Tumor necrosis factor receptor superfamily member 17
Search

TNFRSF17

0.97	Tumor necrosis factor receptor superfamily member 17

0.67	GO:0002260	lymphocyte homeostasis
0.59	GO:0007165	signal transduction
0.43	GO:0002250	adaptive immune response
0.38	GO:0071356	cellular response to tumor necrosis factor
0.38	GO:0008283	cell proliferation
0.36	GO:0007275	multicellular organism development

0.62

GO:0004872

receptor activity

0.36	GO:0012505	endomembrane system
0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|O88477|IF2B1_MOUSE
Insulin-like growth factor 2 mRNA-binding protein 1
Search

IGF2BP1

0.93	Insulin like growth factor 2 mRNA binding protein 1

0.60	GO:0010610	regulation of mRNA stability involved in response to stress
0.60	GO:0022013	pallium cell proliferation in forebrain
0.59	GO:0070934	CRD-mediated mRNA stabilization
0.56	GO:0097150	neuronal stem cell population maintenance
0.52	GO:0017148	negative regulation of translation
0.41	GO:0051028	mRNA transport
0.38	GO:0051239	regulation of multicellular organismal process
0.38	GO:0031346	positive regulation of cell projection organization
0.38	GO:0010720	positive regulation of cell development
0.37	GO:0120035	regulation of plasma membrane bounded cell projection organization

0.63	GO:0003730	mRNA 3'-UTR binding
0.60	GO:0048027	mRNA 5'-UTR binding
0.54	GO:0045182	translation regulator activity
0.35	GO:0005515	protein binding
0.33	GO:0003677	DNA binding

0.58	GO:0070937	CRD-mediated mRNA stability complex
0.53	GO:0010494	cytoplasmic stress granule
0.52	GO:0005829	cytosol
0.48	GO:0005654	nucleoplasm
0.42	GO:0030175	filopodium
0.42	GO:0030426	growth cone
0.40	GO:0030027	lamellipodium
0.39	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0043197	dendritic spine
0.38	GO:0030424	axon

sp|O88485|DC1I1_MOUSE
Cytoplasmic dynein 1 intermediate chain 1
Search

DYNC1I1

0.87	Cytoplasmic dynein 1 intermediate chain 1

0.70	GO:0007018	microtubule-based movement
0.56	GO:0099518	vesicle cytoskeletal trafficking
0.49	GO:2000582	positive regulation of ATP-dependent microtubule motor activity, plus-end-directed
0.36	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0007420	brain development
0.35	GO:0006888	ER to Golgi vesicle-mediated transport
0.35	GO:0007062	sister chromatid cohesion
0.34	GO:0075733	intracellular transport of virus

0.59	GO:0045503	dynein light chain binding
0.56	GO:0030507	spectrin binding
0.48	GO:0045504	dynein heavy chain binding
0.48	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed
0.37	GO:0008017	microtubule binding

0.78	GO:0005868	cytoplasmic dynein complex
0.55	GO:0055037	recycling endosome
0.53	GO:0000922	spindle pole
0.53	GO:0036464	cytoplasmic ribonucleoprotein granule
0.53	GO:0000776	kinetochore
0.45	GO:0005634	nucleus
0.38	GO:0000779	condensed chromosome, centromeric region
0.38	GO:0005874	microtubule
0.38	GO:0048471	perinuclear region of cytoplasm
0.37	GO:1990257	piccolo-bassoon transport vesicle

0.48

EC:3.6.4.4

GO:0008574

sp|O88487|DC1I2_MOUSE
Cytoplasmic dynein 1 intermediate chain 2
Search

DYNC1I2

0.90	Dynein cytoplasmic 1 intermediate chain 2

0.73	GO:0007018	microtubule-based movement
0.45	GO:2000582	positive regulation of ATP-dependent microtubule motor activity, plus-end-directed
0.43	GO:0030705	cytoskeleton-dependent intracellular transport
0.32	GO:0097711	ciliary basal body-plasma membrane docking
0.32	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.32	GO:1990090	cellular response to nerve growth factor stimulus
0.32	GO:0000086	G2/M transition of mitotic cell cycle
0.32	GO:0010977	negative regulation of neuron projection development
0.32	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.32	GO:0007420	brain development

0.45	GO:0045504	dynein heavy chain binding
0.44	GO:0045503	dynein light chain binding
0.44	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed
0.32	GO:0032403	protein complex binding

0.81	GO:0005868	cytoplasmic dynein complex
0.46	GO:0005813	centrosome
0.45	GO:0005874	microtubule
0.45	GO:0031982	vesicle
0.33	GO:0005737	cytoplasm
0.32	GO:0030426	growth cone
0.32	GO:0043025	neuronal cell body
0.32	GO:0030424	axon
0.31	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.44

EC:3.6.4.4

GO:0008574

sp|O88491|NSD1_MOUSE
Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific
Search

NSD1

0.41	Histone-lysine N-methyltransferase

0.78	GO:0034968	histone lysine methylation
0.55	GO:0000414	regulation of histone H3-K36 methylation
0.54	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding
0.53	GO:0033135	regulation of peptidyl-serine phosphorylation
0.48	GO:0045893	positive regulation of transcription, DNA-templated
0.42	GO:0001702	gastrulation with mouth forming second
0.40	GO:0000122	negative regulation of transcription by RNA polymerase II
0.35	GO:0006351	transcription, DNA-templated

0.79	GO:0018024	histone-lysine N-methyltransferase activity
0.55	GO:0050681	androgen receptor binding
0.53	GO:0046872	metal ion binding
0.51	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.49	GO:0003712	transcription cofactor activity
0.43	GO:0046965	retinoid X receptor binding
0.43	GO:0046966	thyroid hormone receptor binding
0.43	GO:0030331	estrogen receptor binding
0.40	GO:0003682	chromatin binding
0.38	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.38	GO:0034708	methyltransferase complex
0.36	GO:0005694	chromosome
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part

0.79

GO:0018024

sp|O88492|PLIN4_MOUSE
Perilipin-4
Search

PLIN4

0.89	Perilipin 4

0.59	GO:0042157	lipoprotein metabolic process
0.59	GO:0006869	lipid transport
0.34	GO:0009405	pathogenesis

0.57

GO:0008289

lipid binding

0.74	GO:0005811	lipid droplet
0.63	GO:0005829	cytosol
0.54	GO:0005576	extracellular region
0.52	GO:0043231	intracellular membrane-bounded organelle
0.52	GO:0005886	plasma membrane
0.36	GO:0019867	outer membrane
0.35	GO:0044462	external encapsulating structure part
0.34	GO:0030313	cell envelope
0.30	GO:0044425	membrane part

sp|O88495|MTR1L_MOUSE
Melatonin-related receptor
Search

GPR50

0.97	G protein-coupled receptor 50

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:0007267	cell-cell signaling

0.85	GO:0008502	melatonin receptor activity
0.62	GO:0042802	identical protein binding

0.59	GO:0005654	nucleoplasm
0.49	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|O88502|PDE8A_MOUSE
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
Search

PDE8A

0.56	Phosphodiesterase

0.61	GO:0007165	signal transduction
0.54	GO:0071364	cellular response to epidermal growth factor stimulus
0.52	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.52	GO:1903206	negative regulation of hydrogen peroxide-induced cell death
0.46	GO:0006355	regulation of transcription, DNA-templated
0.37	GO:0006198	cAMP catabolic process
0.36	GO:0046676	negative regulation of insulin secretion
0.35	GO:0035106	operant conditioning
0.35	GO:0090032	negative regulation of steroid hormone biosynthetic process
0.35	GO:0001662	behavioral fear response

0.79	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.54	GO:0046872	metal ion binding
0.48	GO:0019900	kinase binding

0.36	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol

0.79

GO:0004114

sp|O88507|CNTFR_MOUSE
Ciliary neurotrophic factor receptor subunit alpha
Search

CNTFR

0.97	Ciliary neurotrophic factor receptor subunit alpha

0.77	GO:0019221	cytokine-mediated signaling pathway
0.64	GO:0003360	brainstem development
0.62	GO:0001967	suckling behavior
0.59	GO:0043524	negative regulation of neuron apoptotic process
0.58	GO:0060538	skeletal muscle organ development
0.57	GO:0007548	sex differentiation
0.56	GO:0008284	positive regulation of cell proliferation
0.41	GO:0048680	positive regulation of axon regeneration

0.79	GO:0004896	cytokine receptor activity
0.58	GO:0019955	cytokine binding
0.52	GO:0005102	receptor binding

0.64	GO:0097059	CNTFR-CLCF1 complex
0.63	GO:0070110	ciliary neurotrophic factor receptor complex
0.57	GO:0016324	apical plasma membrane
0.41	GO:0031225	anchored component of membrane
0.35	GO:0019898	extrinsic component of membrane

sp|O88508|DNM3A_MOUSE
DNA (cytosine-5)-methyltransferase 3A
Search

DNMT3A

0.87	DNA methyltransferase 3 alpha

0.74	GO:0006306	DNA methylation
0.64	GO:1901538	changes to DNA methylation involved in embryo development
0.63	GO:0006346	methylation-dependent chromatin silencing
0.62	GO:0006349	regulation of gene expression by genetic imprinting
0.59	GO:0071230	cellular response to amino acid stimulus
0.57	GO:0007283	spermatogenesis
0.56	GO:0022412	cellular process involved in reproduction in multicellular organism
0.56	GO:0000122	negative regulation of transcription by RNA polymerase II

0.76	GO:0009008	DNA-methyltransferase activity
0.55	GO:0003682	chromatin binding
0.55	GO:0042802	identical protein binding
0.52	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.44	GO:0003677	DNA binding

0.62	GO:0001741	XY body
0.61	GO:0000791	euchromatin
0.61	GO:0016363	nuclear matrix
0.59	GO:0005720	nuclear heterochromatin
0.55	GO:0000775	chromosome, centromeric region
0.53	GO:0005654	nucleoplasm
0.41	GO:0005737	cytoplasm

0.76

GO:0009008

sp|O88509|DNM3B_MOUSE
DNA (cytosine-5)-methyltransferase 3B
Search

DNMT3B

0.90	DNA methyltransferase 3 beta

0.68	GO:0006306	DNA methylation
0.59	GO:0051573	negative regulation of histone H3-K9 methylation
0.59	GO:0051571	positive regulation of histone H3-K4 methylation
0.53	GO:0000122	negative regulation of transcription by RNA polymerase II
0.50	GO:0010628	positive regulation of gene expression
0.44	GO:0061484	hematopoietic stem cell homeostasis
0.44	GO:1902036	regulation of hematopoietic stem cell differentiation
0.42	GO:1901538	changes to DNA methylation involved in embryo development
0.42	GO:0006346	methylation-dependent chromatin silencing
0.42	GO:0060821	inactivation of X chromosome by DNA methylation

0.69	GO:0009008	DNA-methyltransferase activity
0.55	GO:0003714	transcription corepressor activity
0.49	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.40	GO:0042826	histone deacetylase binding
0.39	GO:0003682	chromatin binding
0.36	GO:0003677	DNA binding
0.35	GO:0046872	metal ion binding
0.35	GO:0008017	microtubule binding
0.34	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0042802	identical protein binding

0.49	GO:0005654	nucleoplasm
0.41	GO:0005720	nuclear heterochromatin
0.39	GO:0000775	chromosome, centromeric region
0.36	GO:0000791	euchromatin
0.36	GO:0016363	nuclear matrix
0.35	GO:0001741	XY body
0.35	GO:0005874	microtubule
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.69

GO:0009008

sp|O88512|AP1G2_MOUSE
AP-1 complex subunit gamma-like 2
Search

AP1G2

0.80	AP-1 complex subunit gamma-1

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.53	GO:0043323	positive regulation of natural killer cell degranulation
0.52	GO:0035646	endosome to melanosome transport
0.49	GO:0007041	lysosomal transport
0.48	GO:0016482	cytosolic transport
0.38	GO:0033339	pectoral fin development
0.35	GO:0016050	vesicle organization
0.35	GO:0099532	synaptic vesicle endosomal processing
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II

0.51	GO:0030742	GTP-dependent protein binding
0.50	GO:0019894	kinesin binding
0.48	GO:0017137	Rab GTPase binding
0.34	GO:0008022	protein C-terminus binding
0.34	GO:0005518	collagen binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0005215	transporter activity
0.30	GO:0003824	catalytic activity

0.78	GO:0030131	clathrin adaptor complex
0.70	GO:0005794	Golgi apparatus
0.55	GO:0031410	cytoplasmic vesicle
0.44	GO:0005829	cytosol
0.38	GO:0012506	vesicle membrane
0.38	GO:0098805	whole membrane
0.38	GO:0098588	bounding membrane of organelle
0.37	GO:0031984	organelle subcompartment
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005764	lysosome

sp|O88513|GEMI_MOUSE
Geminin
Search

GMNN

0.89	Geminin, DNA replication inhibitor

0.81	GO:0008156	negative regulation of DNA replication
0.77	GO:0045786	negative regulation of cell cycle
0.73	GO:0035563	positive regulation of chromatin binding
0.73	GO:0071163	DNA replication preinitiation complex assembly
0.65	GO:0090329	regulation of DNA-dependent DNA replication
0.65	GO:0048513	animal organ development
0.61	GO:0045892	negative regulation of transcription, DNA-templated
0.60	GO:0009653	anatomical structure morphogenesis
0.58	GO:0006461	protein complex assembly
0.50	GO:0070121	Kupffer's vesicle development

0.70	GO:0070491	repressing transcription factor binding
0.69	GO:0042826	histone deacetylase binding
0.67	GO:0003714	transcription corepressor activity
0.63	GO:0003682	chromatin binding

0.58	GO:0005829	cytosol
0.53	GO:0005634	nucleus

sp|O88516|DLL3_MOUSE
Delta-like protein 3
Search

DLL3

0.97	Delta like canonical Notch ligand 3

0.68	GO:0007386	compartment pattern specification
0.65	GO:0048339	paraxial mesoderm development
0.65	GO:0007219	Notch signaling pathway
0.64	GO:0001756	somitogenesis
0.62	GO:0050768	negative regulation of neurogenesis
0.60	GO:0001501	skeletal system development
0.44	GO:0045165	cell fate commitment
0.42	GO:0008593	regulation of Notch signaling pathway
0.42	GO:0007417	central nervous system development
0.41	GO:0048633	positive regulation of skeletal muscle tissue growth

0.70	GO:0005509	calcium ion binding
0.47	GO:0005112	Notch binding
0.41	GO:0030957	Tat protein binding
0.41	GO:0004872	receptor activity
0.40	GO:0097110	scaffold protein binding
0.34	GO:0030165	PDZ domain binding
0.33	GO:0046982	protein heterodimerization activity
0.32	GO:0042802	identical protein binding

0.39	GO:0016324	apical plasma membrane
0.39	GO:0098857	membrane microdomain
0.39	GO:0005912	adherens junction
0.37	GO:0031410	cytoplasmic vesicle
0.37	GO:0009986	cell surface
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005938	cell cortex
0.33	GO:0000139	Golgi membrane
0.33	GO:0005887	integral component of plasma membrane
0.33	GO:0005789	endoplasmic reticulum membrane

sp|O88520|SHOC2_MOUSE
Leucine-rich repeat protein SHOC-2
Search

SHOC2

0.80	Leucine-rich repeat protein SHOC-2

0.84	GO:0046579	positive regulation of Ras protein signal transduction
0.62	GO:0007265	Ras protein signal transduction
0.60	GO:0043666	regulation of phosphoprotein phosphatase activity
0.40	GO:0008543	fibroblast growth factor receptor signaling pathway

0.84	GO:0008157	protein phosphatase 1 binding
0.61	GO:0019888	protein phosphatase regulator activity

0.84	GO:0000164	protein phosphatase type 1 complex
0.68	GO:0005654	nucleoplasm
0.67	GO:0005829	cytosol
0.46	GO:0005886	plasma membrane

sp|O88522|NEMO_MOUSE
NF-kappa-B essential modulator
Search

IKBKG

0.93	Inhibitor of kappa light polypeptide gene enhancer in B-cells kinase gamma

0.62	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.58	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.56	GO:0051650	establishment of vesicle localization
0.53	GO:0045944	positive regulation of transcription by RNA polymerase II
0.48	GO:0006974	cellular response to DNA damage stimulus
0.48	GO:0016310	phosphorylation
0.42	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.37	GO:0036211	protein modification process
0.36	GO:0044267	cellular protein metabolic process

0.85	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding
0.64	GO:1990450	linear polyubiquitin binding
0.56	GO:0031625	ubiquitin protein ligase binding
0.54	GO:0019904	protein domain specific binding
0.53	GO:0042803	protein homodimerization activity
0.53	GO:0046982	protein heterodimerization activity
0.48	GO:0016301	kinase activity
0.41	GO:0042975	peroxisome proliferator activated receptor binding

0.64	GO:0008385	IkappaB kinase complex
0.56	GO:0072686	mitotic spindle
0.56	GO:0000922	spindle pole
0.54	GO:0000151	ubiquitin ligase complex
0.48	GO:0005634	nucleus

sp|O88531|PPT1_MOUSE
Palmitoyl-protein thioesterase 1
Search

PPT1

0.83	Palmitoyl-protein thioesterase

0.84	GO:0002084	protein depalmitoylation
0.57	GO:0032429	regulation of phospholipase A2 activity
0.57	GO:0007625	grooming behavior
0.55	GO:0007040	lysosome organization
0.55	GO:0008306	associative learning
0.54	GO:0008344	adult locomotory behavior
0.53	GO:0099643	signal release from synapse
0.53	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.52	GO:0007601	visual perception
0.50	GO:0006836	neurotransmitter transport

0.84	GO:0008474	palmitoyl-(protein) hydrolase activity
0.43	GO:0016290	palmitoyl-CoA hydrolase activity
0.35	GO:0005515	protein binding

0.55	GO:0005764	lysosome
0.53	GO:0030424	axon
0.53	GO:0098793	presynapse
0.53	GO:0043025	neuronal cell body
0.52	GO:0030425	dendrite
0.50	GO:0005615	extracellular space
0.42	GO:0070382	exocytic vesicle
0.41	GO:0045121	membrane raft
0.39	GO:0005794	Golgi apparatus
0.39	GO:0005829	cytosol

0.84

EC:3.1.2.22

GO:0008474

sp|O88532|ZFR_MOUSE
Zinc finger RNA-binding protein
Search

ZFR

0.91	zinc finger RNA-binding protein isoform X1

0.39	GO:0007275	multicellular organism development
0.33	GO:0006955	immune response

0.62	GO:0008270	zinc ion binding
0.50	GO:0003676	nucleic acid binding
0.35	GO:0005515	protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016740	transferase activity

0.37	GO:0005634	nucleus
0.37	GO:0005694	chromosome
0.35	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.32

GO:0016740

sp|O88533|DDC_MOUSE
Aromatic-L-amino-acid decarboxylase
Search

DDC

0.74	Aromatic-L-amino-acid decarboxylase

0.60	GO:0006520	cellular amino acid metabolic process
0.48	GO:0009636	response to toxic substance
0.45	GO:0042416	dopamine biosynthetic process
0.43	GO:0033076	isoquinoline alkaloid metabolic process
0.42	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle
0.42	GO:0007275	multicellular organism development
0.42	GO:0052314	phytoalexin metabolic process
0.42	GO:0060322	head development
0.42	GO:0042427	serotonin biosynthetic process
0.42	GO:0071312	cellular response to alkaloid

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.49	GO:0019899	enzyme binding
0.39	GO:0019904	protein domain specific binding
0.39	GO:0016597	amino acid binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0008021	synaptic vesicle
0.40	GO:0043025	neuronal cell body
0.40	GO:0030424	axon
0.36	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.68

EC:4.1.1

GO:0016831

sp|O88536|FPR2_MOUSE
Formyl peptide receptor 2
Search

0.95	Formyl peptide receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.56	GO:0002430	complement receptor mediated signaling pathway
0.53	GO:0050900	leukocyte migration
0.52	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.52	GO:0060326	cell chemotaxis
0.52	GO:0006954	inflammatory response
0.50	GO:1904646	cellular response to amyloid-beta
0.50	GO:0090026	positive regulation of monocyte chemotaxis
0.48	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.48	GO:0019722	calcium-mediated signaling

0.85	GO:0004982	N-formyl peptide receptor activity
0.56	GO:0004875	complement receptor activity
0.53	GO:0005124	scavenger receptor binding
0.39	GO:0050786	RAGE receptor binding
0.36	GO:0038024	cargo receptor activity

0.46	GO:0005887	integral component of plasma membrane
0.38	GO:0101003	ficolin-1-rich granule membrane
0.36	GO:0035579	specific granule membrane
0.36	GO:0070821	tertiary granule membrane
0.35	GO:0035577	azurophil granule membrane

sp|O88537|FPRS3_MOUSE
Formyl peptide receptor-related sequence 3
Search

0.96	Formyl peptide receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.57	GO:0002430	complement receptor mediated signaling pathway
0.52	GO:0050900	leukocyte migration
0.52	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.52	GO:0060326	cell chemotaxis
0.51	GO:0006954	inflammatory response
0.48	GO:0071675	regulation of mononuclear cell migration
0.48	GO:1904646	cellular response to amyloid-beta
0.48	GO:0002690	positive regulation of leukocyte chemotaxis
0.47	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.84	GO:0004982	N-formyl peptide receptor activity
0.57	GO:0004875	complement receptor activity
0.51	GO:0005124	scavenger receptor binding
0.38	GO:0050786	RAGE receptor binding
0.36	GO:0038024	cargo receptor activity
0.36	GO:0001847	opsonin receptor activity
0.34	GO:0004950	chemokine receptor activity

0.46	GO:0005887	integral component of plasma membrane
0.37	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0035579	specific granule membrane
0.35	GO:0070821	tertiary granule membrane
0.35	GO:0035577	azurophil granule membrane
0.34	GO:0060417	yolk
0.32	GO:0005829	cytosol

sp|O88543|CSN3_MOUSE
COP9 signalosome complex subunit 3
Search

COPS3

0.89	COP9 constitutive photomorphogenic homolog subunit 3

0.56	GO:0000338	protein deneddylation
0.51	GO:0001701	in utero embryonic development
0.44	GO:0006511	ubiquitin-dependent protein catabolic process
0.35	GO:0043687	post-translational protein modification
0.34	GO:0000715	nucleotide-excision repair, DNA damage recognition
0.34	GO:0006283	transcription-coupled nucleotide-excision repair
0.34	GO:0009416	response to light stimulus
0.33	GO:0065009	regulation of molecular function
0.33	GO:0007165	signal transduction

0.35	GO:0005515	protein binding
0.33	GO:0098772	molecular function regulator
0.30	GO:0003824	catalytic activity

0.76	GO:0008180	COP9 signalosome
0.49	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol

sp|O88544|CSN4_MOUSE
COP9 signalosome complex subunit 4
Search

COPS4

0.88	COP9 constitutive photomorphogenic homolog subunit 4

0.47	GO:0000338	protein deneddylation
0.34	GO:0043687	post-translational protein modification
0.34	GO:0000715	nucleotide-excision repair, DNA damage recognition
0.34	GO:0006283	transcription-coupled nucleotide-excision repair

0.47	GO:0019784	NEDD8-specific protease activity
0.35	GO:0005515	protein binding

0.79	GO:0008180	COP9 signalosome
0.43	GO:0008021	synaptic vesicle
0.41	GO:0005829	cytosol
0.41	GO:0030054	cell junction
0.38	GO:0016607	nuclear speck
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|O88545|CSN6_MOUSE
COP9 signalosome complex subunit 6
Search

COPS6

0.70	Eukaryotic translation initiation factor 3 subunit F

0.84	GO:0000338	protein deneddylation
0.39	GO:0048140	male germ-line cyst encapsulation
0.38	GO:0036099	female germ-line stem cell population maintenance
0.37	GO:0050821	protein stabilization
0.37	GO:0007281	germ cell development
0.35	GO:0021551	central nervous system morphogenesis
0.35	GO:0060026	convergent extension
0.35	GO:0043687	post-translational protein modification
0.35	GO:1904888	cranial skeletal system development
0.34	GO:0009953	dorsal/ventral pattern formation

0.36	GO:0005515	protein binding
0.33	GO:0003743	translation initiation factor activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0016787	hydrolase activity

0.81	GO:0008180	COP9 signalosome
0.47	GO:0005654	nucleoplasm
0.36	GO:0070062	extracellular exosome
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

sp|O88551|CLD1_MOUSE
Claudin-1
Search

CLDN1

0.66

Claudin

0.59	GO:0043297	apical junction assembly
0.58	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.57	GO:0061436	establishment of skin barrier
0.55	GO:0051291	protein heterooligomerization
0.51	GO:0051260	protein homooligomerization
0.47	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.47	GO:0044409	entry into host
0.46	GO:0019227	neuronal action potential propagation
0.46	GO:0019058	viral life cycle
0.42	GO:0061772	drug transport across blood-nerve barrier

0.62	GO:0005198	structural molecule activity
0.57	GO:0104005	hijacked molecular function
0.50	GO:0042802	identical protein binding
0.35	GO:0050839	cell adhesion molecule binding
0.32	GO:0016787	hydrolase activity

0.81	GO:0005923	bicellular tight junction
0.61	GO:0016323	basolateral plasma membrane
0.59	GO:0016328	lateral plasma membrane
0.53	GO:0016324	apical plasma membrane
0.47	GO:0005887	integral component of plasma membrane
0.47	GO:0016327	apicolateral plasma membrane
0.38	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm

0.32

GO:0016787

sp|O88552|CLD2_MOUSE
Claudin-2
Search

CLDN2

0.68

Claudin

0.64	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.33	GO:0006461	protein complex assembly

0.62	GO:0005198	structural molecule activity
0.54	GO:0042802	identical protein binding

0.81	GO:0005923	bicellular tight junction
0.55	GO:0005886	plasma membrane
0.39	GO:0070062	extracellular exosome
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0044425	membrane part

sp|O88554|PARP2_MOUSE
Poly [ADP-ribose] polymerase 2
Search

PARP2

0.58	Poly [ADP-ribose] polymerase

0.83	GO:0006471	protein ADP-ribosylation
0.55	GO:0097191	extrinsic apoptotic signaling pathway
0.53	GO:0018209	peptidyl-serine modification
0.49	GO:0006284	base-excision repair
0.49	GO:0006273	lagging strand elongation
0.48	GO:0051103	DNA ligation involved in DNA repair
0.38	GO:0035080	heat shock-mediated polytene chromosome puffing
0.37	GO:0008069	dorsal/ventral axis specification, ovarian follicular epithelium
0.37	GO:0006963	positive regulation of antibacterial peptide biosynthetic process
0.37	GO:0030576	Cajal body organization

0.81	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.59	GO:1990404	protein ADP-ribosylase activity
0.48	GO:0003910	DNA ligase (ATP) activity
0.46	GO:0008270	zinc ion binding
0.38	GO:0051287	NAD binding
0.37	GO:0003677	DNA binding
0.36	GO:0005515	protein binding

0.50	GO:0005730	nucleolus
0.48	GO:0005654	nucleoplasm
0.37	GO:0005737	cytoplasm
0.37	GO:0005703	polytene chromosome puff
0.37	GO:0005719	nuclear euchromatin
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:2.4.2.30

GO:0003950

sp|O88559|MEN1_MOUSE
Menin
Search

MEN1

0.96	Mmultiple endocrine neoplasia i

0.57	GO:0002076	osteoblast development
0.56	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.56	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity
0.56	GO:0051974	negative regulation of telomerase activity
0.56	GO:0046329	negative regulation of JNK cascade
0.55	GO:0045668	negative regulation of osteoblast differentiation
0.55	GO:0010332	response to gamma radiation
0.54	GO:0032092	positive regulation of protein binding
0.54	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.54	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway

0.58	GO:0000403	Y-form DNA binding
0.56	GO:0070412	R-SMAD binding
0.55	GO:0000400	four-way junction DNA binding
0.55	GO:0047485	protein N-terminus binding
0.53	GO:0018024	histone-lysine N-methyltransferase activity
0.52	GO:0030674	protein binding, bridging
0.52	GO:0044212	transcription regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.46	GO:0003682	chromatin binding
0.35	GO:0043565	sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.55	GO:0097610	cell surface furrow
0.53	GO:0032155	cell division site part
0.52	GO:0034708	methyltransferase complex
0.50	GO:0000785	chromatin
0.48	GO:0070013	intracellular organelle lumen
0.47	GO:0005829	cytosol
0.43	GO:0043234	protein complex
0.38	GO:0000781	chromosome, telomeric region
0.34	GO:0044432	endoplasmic reticulum part

0.53

GO:0018024

sp|O88561|S27A3_MOUSE
Long-chain fatty acid transport protein 3
Search

SLC27A3

0.88	Very long-chain acyl-CoA synthetase

0.75	GO:0001676	long-chain fatty acid metabolic process
0.61	GO:0015908	fatty acid transport
0.50	GO:0006699	bile acid biosynthetic process
0.50	GO:0097089	methyl-branched fatty acid metabolic process
0.49	GO:0001561	fatty acid alpha-oxidation
0.48	GO:0042760	very long-chain fatty acid catabolic process
0.44	GO:0006635	fatty acid beta-oxidation
0.35	GO:0035383	thioester metabolic process
0.34	GO:0043312	neutrophil degranulation
0.34	GO:0006732	coenzyme metabolic process

0.82	GO:0031957	very long-chain fatty acid-CoA ligase activity
0.76	GO:0004467	long-chain fatty acid-CoA ligase activity
0.50	GO:0070251	pristanate-CoA ligase activity
0.50	GO:0050197	phytanate-CoA ligase activity
0.50	GO:0015245	fatty acid transmembrane transporter activity
0.43	GO:0005102	receptor binding
0.43	GO:0019899	enzyme binding
0.39	GO:0004321	fatty-acyl-CoA synthase activity
0.37	GO:0102391	decanoate--CoA ligase activity
0.35	GO:0008756	o-succinylbenzoate-CoA ligase activity

0.54	GO:0005783	endoplasmic reticulum
0.45	GO:0005779	integral component of peroxisomal membrane
0.43	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.42	GO:0031974	membrane-enclosed lumen
0.42	GO:0031984	organelle subcompartment
0.41	GO:0005739	mitochondrion
0.35	GO:0070062	extracellular exosome
0.34	GO:0035579	specific granule membrane
0.34	GO:0042383	sarcolemma
0.33	GO:0031967	organelle envelope

0.76	EC:6.2.1.3	GO:0004467
0.50	KEGG:R03631	GO:0050197

sp|O88566|AXIN2_MOUSE
Axin-2
Search

AXIN2

0.97	Axin 2 (conductin, axil)

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0032423	regulation of mismatch repair
0.70	GO:0070602	regulation of centromeric sister chromatid cohesion
0.68	GO:0001957	intramembranous ossification
0.68	GO:0035414	negative regulation of catenin import into nucleus
0.67	GO:0003139	secondary heart field specification
0.66	GO:0061181	regulation of chondrocyte development
0.66	GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis
0.66	GO:0048255	mRNA stabilization
0.66	GO:0010718	positive regulation of epithelial to mesenchymal transition

0.67	GO:0070411	I-SMAD binding
0.61	GO:0031625	ubiquitin protein ligase binding
0.48	GO:0005096	GTPase activator activity
0.40	GO:0008013	beta-catenin binding
0.36	GO:0019901	protein kinase binding

0.60	GO:0005813	centrosome
0.50	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm
0.40	GO:0005886	plasma membrane
0.35	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|O88569|ROA2_MOUSE
Heterogeneous nuclear ribonucleoproteins A2/B1
Search

HNRNPA2B1

0.77	Heterogeneous nuclear ribonucleoprotein A2 homolog 1

0.79	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.75	GO:0051028	mRNA transport
0.74	GO:0006405	RNA export from nucleus
0.69	GO:0006397	mRNA processing
0.61	GO:1990428	miRNA transport
0.58	GO:0031053	primary miRNA processing
0.56	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.52	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
0.51	GO:0000122	negative regulation of transcription by RNA polymerase II
0.36	GO:1905661	regulation of telomerase RNA reverse transcriptase activity

0.59	GO:1990247	N6-methyladenosine-containing RNA binding
0.58	GO:0035198	miRNA binding
0.57	GO:0097157	pre-mRNA intronic binding
0.56	GO:0043047	single-stranded telomeric DNA binding
0.55	GO:0003730	mRNA 3'-UTR binding
0.35	GO:0042802	identical protein binding
0.35	GO:1990715	mRNA CDS binding
0.35	GO:0001069	regulatory region RNA binding
0.34	GO:0070182	DNA polymerase binding

0.59	GO:0019013	viral nucleocapsid
0.57	GO:0030529	intracellular ribonucleoprotein complex
0.54	GO:0070062	extracellular exosome
0.50	GO:0005654	nucleoplasm
0.45	GO:1902494	catalytic complex
0.39	GO:0005737	cytoplasm
0.35	GO:0016363	nuclear matrix
0.35	GO:0000781	chromosome, telomeric region
0.34	GO:0043204	perikaryon
0.33	GO:0043005	neuron projection

sp|O88572|LRP6_MOUSE
Low-density lipoprotein receptor-related protein 6
Search

0.47	Low-density lipoprotein receptor-related protein 5

0.67	GO:0060070	canonical Wnt signaling pathway
0.50	GO:0007275	multicellular organism development
0.44	GO:0060828	regulation of canonical Wnt signaling pathway
0.44	GO:0051091	positive regulation of DNA binding transcription factor activity
0.44	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.44	GO:0045787	positive regulation of cell cycle
0.43	GO:0035426	extracellular matrix-cell signaling
0.43	GO:0051094	positive regulation of developmental process
0.43	GO:0033690	positive regulation of osteoblast proliferation
0.43	GO:0002076	osteoblast development

0.68	GO:0017147	Wnt-protein binding
0.68	GO:0042813	Wnt-activated receptor activity
0.60	GO:0071936	coreceptor activity involved in Wnt signaling pathway
0.41	GO:0005041	low-density lipoprotein receptor activity
0.41	GO:0005109	frizzled binding
0.40	GO:0019534	toxin transmembrane transporter activity
0.40	GO:0019210	kinase inhibitor activity
0.38	GO:0042803	protein homodimerization activity
0.34	GO:0034185	apolipoprotein binding

0.42	GO:1990851	Wnt-Frizzled-LRP5/6 complex
0.41	GO:1990909	Wnt signalosome
0.41	GO:0043235	receptor complex
0.40	GO:0005901	caveola
0.39	GO:0005769	early endosome
0.38	GO:0009986	cell surface
0.38	GO:0005794	Golgi apparatus
0.37	GO:0005739	mitochondrion
0.34	GO:0043025	neuronal cell body
0.33	GO:0045202	synapse

sp|O88573|AFF1_MOUSE
AF4/FMR2 family member 1
Search

sp|O88574|SAP30_MOUSE
Histone deacetylase complex subunit SAP30
Search

SAP30

0.93	Histone deacetylase complex subunit SAP30

0.73	GO:0035914	skeletal muscle cell differentiation
0.67	GO:0000122	negative regulation of transcription by RNA polymerase II
0.60	GO:0016575	histone deacetylation
0.50	GO:0001947	heart looping
0.38	GO:0000183	chromatin silencing at rDNA
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:0006486	protein glycosylation

0.70	GO:0003714	transcription corepressor activity
0.61	GO:0044378	non-sequence-specific DNA binding, bending
0.60	GO:0004407	histone deacetylase activity
0.59	GO:0010314	phosphatidylinositol-5-phosphate binding
0.56	GO:0031491	nucleosome binding
0.55	GO:0042393	histone binding
0.46	GO:0008270	zinc ion binding
0.38	GO:0070273	phosphatidylinositol-4-phosphate binding
0.38	GO:0032266	phosphatidylinositol-3-phosphate binding
0.36	GO:0030246	carbohydrate binding

0.74	GO:0000118	histone deacetylase complex
0.51	GO:0005730	nucleolus
0.37	GO:0000790	nuclear chromatin
0.37	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.60

GO:0004407

sp|O88575|S620B_MOUSE
Sodium- and chloride-dependent transporter XTRP3B
Search

SLC6A20

0.71	Solute carrier family 6 member 20

0.76	GO:0006836	neurotransmitter transport
0.62	GO:0015824	proline transport
0.60	GO:0015807	L-amino acid transport
0.58	GO:0015838	amino-acid betaine transport
0.57	GO:0003333	amino acid transmembrane transport
0.55	GO:0015893	drug transport
0.47	GO:0098655	cation transmembrane transport

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.59	GO:0015193	L-proline transmembrane transporter activity

0.66	GO:0005887	integral component of plasma membrane
0.58	GO:0016324	apical plasma membrane

sp|O88576|S6A18_MOUSE
Sodium-dependent neutral amino acid transporter B(0)AT3
Search

SLC6A18

0.64	Sodium-dependent neutral amino acid transporter B(0)AT3

0.76	GO:0006836	neurotransmitter transport
0.55	GO:0055085	transmembrane transport
0.54	GO:0006865	amino acid transport
0.48	GO:0007584	response to nutrient
0.45	GO:0006972	hyperosmotic response

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.48	GO:0015171	amino acid transmembrane transporter activity
0.41	GO:0005515	protein binding

0.66	GO:0005887	integral component of plasma membrane
0.62	GO:0031526	brush border membrane
0.45	GO:0070062	extracellular exosome

sp|O88587|COMT_MOUSE
Catechol O-methyltransferase
Search

COMT

0.54	Membrane bound catechol-O-methyltransferase

0.81	GO:0006584	catecholamine metabolic process
0.70	GO:0042135	neurotransmitter catabolic process
0.63	GO:0032259	methylation
0.54	GO:0016036	cellular response to phosphate starvation
0.52	GO:0019614	catechol-containing compound catabolic process
0.50	GO:0097164	ammonium ion metabolic process
0.48	GO:0042737	drug catabolic process
0.46	GO:1901565	organonitrogen compound catabolic process
0.43	GO:0050668	positive regulation of homocysteine metabolic process
0.42	GO:0045963	negative regulation of dopamine metabolic process

0.84	GO:0016206	catechol O-methyltransferase activity
0.61	GO:0000287	magnesium ion binding
0.45	GO:0102084	L-dopa O-methyltransferase activity
0.45	GO:0102938	orcinol O-methyltransferase activity
0.33	GO:0005515	protein binding

0.44	GO:0005739	mitochondrion
0.40	GO:0043197	dendritic spine
0.39	GO:0044297	cell body
0.39	GO:0030424	axon
0.39	GO:0045211	postsynaptic membrane
0.37	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.84

EC:2.1.1.6

GO:0016206

sp|O88593|PGRP1_MOUSE
Peptidoglycan recognition protein 1
Search

PGLYRP1

0.80	Peptidoglycan recognition protein 1

0.74	GO:0009253	peptidoglycan catabolic process
0.71	GO:0045087	innate immune response
0.63	GO:0051714	positive regulation of cytolysis in other organism
0.60	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.59	GO:0016045	detection of bacterium
0.59	GO:0050830	defense response to Gram-positive bacterium
0.57	GO:0045089	positive regulation of innate immune response
0.56	GO:0002757	immune response-activating signal transduction
0.55	GO:0031640	killing of cells of other organism
0.53	GO:0032824	negative regulation of natural killer cell differentiation

0.76	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
0.71	GO:0042834	peptidoglycan binding
0.63	GO:0008270	zinc ion binding
0.62	GO:0016019	peptidoglycan receptor activity
0.40	GO:0046982	protein heterodimerization activity
0.36	GO:0005125	cytokine activity
0.33	GO:0004180	carboxypeptidase activity

0.41	GO:0005576	extracellular region
0.37	GO:0043234	protein complex
0.37	GO:0097013	phagocytic vesicle lumen
0.36	GO:1904724	tertiary granule lumen
0.36	GO:0035580	specific granule lumen
0.33	GO:0031314	extrinsic component of mitochondrial inner membrane
0.30	GO:0016021	integral component of membrane

0.76

EC:3.5.1.28

GO:0008745

sp|O88597|BECN1_MOUSE
Beclin-1
Search

BECN1

0.90	Beclin 1 (Coiled-coil, myosin-like BCL2 interacting protein)

0.79	GO:0032465	regulation of cytokinesis
0.77	GO:0006914	autophagy
0.71	GO:0006897	endocytosis
0.55	GO:0045022	early endosome to late endosome transport
0.54	GO:1902425	positive regulation of attachment of mitotic spindle microtubules to kinetochore
0.54	GO:0050435	amyloid-beta metabolic process
0.54	GO:1902902	negative regulation of autophagosome assembly
0.54	GO:0007033	vacuole organization
0.54	GO:0010613	positive regulation of cardiac muscle hypertrophy
0.53	GO:0098780	response to mitochondrial depolarisation

0.53	GO:0043548	phosphatidylinositol 3-kinase binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.49	GO:0019901	protein kinase binding
0.48	GO:0042803	protein homodimerization activity
0.47	GO:0051020	GTPase binding

0.56	GO:0035032	phosphatidylinositol 3-kinase complex, class III
0.54	GO:0005776	autophagosome
0.51	GO:0045335	phagocytic vesicle
0.50	GO:0005768	endosome
0.50	GO:0005802	trans-Golgi network
0.48	GO:0005783	endoplasmic reticulum
0.47	GO:0000407	phagophore assembly site
0.47	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.42	GO:0043234	protein complex

sp|O88602|CCG2_MOUSE
Voltage-dependent calcium channel gamma-2 subunit
Search

CACNG2

0.47	Multifunctional fusion protein (Fragment)

0.70	GO:0034765	regulation of ion transmembrane transport
0.69	GO:0070588	calcium ion transmembrane transport
0.56	GO:0098953	receptor diffusion trapping
0.56	GO:0098943	neurotransmitter receptor transport, postsynaptic endosome to lysosome
0.55	GO:0099590	neurotransmitter receptor internalization
0.54	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels
0.54	GO:0060081	membrane hyperpolarization
0.54	GO:1900449	regulation of glutamate receptor signaling pathway
0.54	GO:0099601	regulation of neurotransmitter receptor activity
0.54	GO:0019226	transmission of nerve impulse

0.73	GO:0005245	voltage-gated calcium channel activity
0.43	GO:0016247	channel regulator activity
0.36	GO:0003700	DNA binding transcription factor activity
0.35	GO:0035255	ionotropic glutamate receptor binding
0.35	GO:0003677	DNA binding

0.73	GO:0005891	voltage-gated calcium channel complex
0.54	GO:0032281	AMPA glutamate receptor complex
0.54	GO:0099634	postsynaptic specialization membrane
0.50	GO:0036477	somatodendritic compartment
0.36	GO:0005622	intracellular
0.35	GO:0014069	postsynaptic density

sp|O88609|LMX1B_MOUSE
LIM homeobox transcription factor 1-beta
Search

LMX1B

0.96	LIM homeobox transcription factor 1 beta

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0030902	hindbrain development
0.53	GO:0071542	dopaminergic neuron differentiation
0.52	GO:0030901	midbrain development
0.52	GO:0042048	olfactory behavior
0.52	GO:0021542	dentate gyrus development
0.51	GO:0007613	memory
0.51	GO:0021953	central nervous system neuron differentiation

0.63	GO:0043565	sequence-specific DNA binding
0.53	GO:0046872	metal ion binding
0.49	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.49	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0003690	double-stranded DNA binding
0.40	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding
0.35	GO:0005515	protein binding

0.60

GO:0005634

nucleus

sp|O88621|FOXH1_MOUSE
Forkhead box protein H1
Search

FOXH1

0.97	Forkhead activin signal transducer 1

0.79	GO:2000824	negative regulation of androgen receptor activity
0.78	GO:0035054	embryonic heart tube anterior/posterior pattern specification
0.76	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway
0.76	GO:0003139	secondary heart field specification
0.76	GO:0048318	axial mesoderm development
0.75	GO:0003222	ventricular trabecula myocardium morphogenesis
0.74	GO:0003215	cardiac right ventricle morphogenesis
0.74	GO:0035909	aorta morphogenesis
0.72	GO:0003151	outflow tract morphogenesis
0.71	GO:0001947	heart looping

0.76	GO:0070410	co-SMAD binding
0.75	GO:0070412	R-SMAD binding
0.75	GO:0050681	androgen receptor binding
0.75	GO:0043425	bHLH transcription factor binding
0.74	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.71	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.66	GO:0001104	RNA polymerase II transcription cofactor activity
0.66	GO:0019904	protein domain specific binding
0.65	GO:0043565	sequence-specific DNA binding
0.65	GO:0044212	transcription regulatory region DNA binding

0.78	GO:0032444	activin responsive factor complex
0.64	GO:0000790	nuclear chromatin
0.36	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

sp|O88622|PARG_MOUSE
Poly(ADP-ribose) glycohydrolase
Search

PARG

0.86	Poly (ADP-ribose) glycohydrolase

0.63	GO:1990966	ATP generation from poly-ADP-D-ribose
0.60	GO:0005975	carbohydrate metabolic process
0.39	GO:0016045	detection of bacterium
0.36	GO:0045739	positive regulation of DNA repair
0.35	GO:0006974	cellular response to DNA damage stimulus
0.34	GO:0006334	nucleosome assembly
0.34	GO:0006468	protein phosphorylation

0.85	GO:0004649	poly(ADP-ribose) glycohydrolase activity
0.35	GO:0003682	chromatin binding
0.35	GO:0004683	calmodulin-dependent protein kinase activity
0.35	GO:0005515	protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.35	GO:0005759	mitochondrial matrix
0.35	GO:0000785	chromatin
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:3.2.1.143

GO:0004649

sp|O88623|UBP2_MOUSE
Ubiquitin carboxyl-terminal hydrolase 2
Search

USP2

0.85	Ubiquitin carboxyl-terminal hydrolase 2

0.76	GO:0016579	protein deubiquitination
0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.59	GO:0043153	entrainment of circadian clock by photoperiod
0.58	GO:0045475	locomotor rhythm
0.57	GO:0032922	circadian regulation of gene expression
0.55	GO:0045931	positive regulation of mitotic cell cycle
0.54	GO:0050821	protein stabilization
0.53	GO:0000122	negative regulation of transcription by RNA polymerase II
0.40	GO:0007517	muscle organ development
0.38	GO:0051926	negative regulation of calcium ion transport

0.76	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.56	GO:0030332	cyclin binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.51	GO:0042802	identical protein binding
0.35	GO:0046872	metal ion binding
0.35	GO:0004197	cysteine-type endopeptidase activity

0.54	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005938	cell cortex
0.45	GO:0005634	nucleus
0.38	GO:0005813	centrosome
0.34	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

0.76

EC:3.4.19.12

GO:0036459

sp|O88627|S28A2_MOUSE
Sodium/nucleoside cotransporter 2
Search

0.86	Sodium/nucleoside cotransporter

0.78	GO:1901642	nucleoside transmembrane transport
0.51	GO:0072530	purine-containing compound transmembrane transport
0.45	GO:0006863	purine nucleobase transport
0.43	GO:0072531	pyrimidine-containing compound transmembrane transport
0.43	GO:0015855	pyrimidine nucleobase transport
0.36	GO:0034394	protein localization to cell surface
0.35	GO:0001895	retina homeostasis
0.32	GO:0046483	heterocycle metabolic process
0.32	GO:1901360	organic cyclic compound metabolic process
0.32	GO:0006725	cellular aromatic compound metabolic process

0.86	GO:0005415	nucleoside:sodium symporter activity
0.47	GO:0015211	purine nucleoside transmembrane transporter activity
0.46	GO:0005345	purine nucleobase transmembrane transporter activity
0.43	GO:0005350	pyrimidine nucleobase transmembrane transporter activity

0.66	GO:0005887	integral component of plasma membrane
0.34	GO:0016324	apical plasma membrane

sp|O88630|GOSR1_MOUSE
Golgi SNAP receptor complex member 1
Search

GOSR1

0.73	Golgi SNAP receptor complex member 1

0.76	GO:0006888	ER to Golgi vesicle-mediated transport
0.58	GO:0015031	protein transport
0.50	GO:0042147	retrograde transport, endosome to Golgi
0.49	GO:0048209	regulation of vesicle targeting, to, from or within Golgi
0.48	GO:0061025	membrane fusion
0.46	GO:0006891	intra-Golgi vesicle-mediated transport
0.46	GO:0048284	organelle fusion
0.45	GO:0016050	vesicle organization

0.53	GO:0005484	SNAP receptor activity
0.46	GO:0000149	SNARE binding

0.80	GO:0005801	cis-Golgi network
0.72	GO:0000139	Golgi membrane
0.48	GO:0005797	Golgi medial cisterna
0.46	GO:0031201	SNARE complex
0.45	GO:0005829	cytosol
0.35	GO:0000138	Golgi trans cisterna
0.34	GO:0030133	transport vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|O88632|SEM3F_MOUSE
Semaphorin-3F
Search

SEMA3F

0.97	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb

0.83	GO:0050919	negative chemotaxis
0.83	GO:0036486	ventral trunk neural crest cell migration
0.83	GO:0097491	sympathetic neuron projection guidance
0.83	GO:0097490	sympathetic neuron projection extension
0.83	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance
0.83	GO:0021637	trigeminal nerve structural organization
0.82	GO:1901166	neural crest cell migration involved in autonomic nervous system development
0.82	GO:0021785	branchiomotor neuron axon guidance
0.82	GO:0021612	facial nerve structural organization
0.81	GO:0048843	negative regulation of axon extension involved in axon guidance

0.82	GO:0045499	chemorepellent activity
0.68	GO:0038191	neuropilin binding
0.34	GO:0003723	RNA binding
0.33	GO:0004871	signal transducer activity

0.70

GO:0005615

extracellular space

sp|O88634|PAR4_MOUSE
Proteinase-activated receptor 4
Search

F2RL3

0.97	F2R like thrombin or trypsin receptor 3

0.80	GO:0070493	thrombin-activated receptor signaling pathway
0.75	GO:0007596	blood coagulation
0.59	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.56	GO:1904064	positive regulation of cation transmembrane transport
0.56	GO:0051279	regulation of release of sequestered calcium ion into cytosol
0.55	GO:0051928	positive regulation of calcium ion transport
0.54	GO:0032846	positive regulation of homeostatic process
0.52	GO:0048522	positive regulation of cellular process
0.50	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.47	GO:0048584	positive regulation of response to stimulus

0.81	GO:0015057	thrombin-activated receptor activity
0.45	GO:0004966	galanin receptor activity
0.42	GO:0017046	peptide hormone binding
0.37	GO:0031681	G-protein beta-subunit binding
0.36	GO:0001965	G-protein alpha-subunit binding
0.36	GO:0004947	bradykinin receptor activity
0.35	GO:0042923	neuropeptide binding
0.34	GO:0004945	angiotensin type II receptor activity
0.33	GO:0004950	chemokine receptor activity
0.33	GO:0008233	peptidase activity

0.44	GO:0005887	integral component of plasma membrane
0.36	GO:0031143	pseudopodium
0.36	GO:0005769	early endosome
0.34	GO:0005576	extracellular region
0.34	GO:0097730	non-motile cilium

0.33

GO:0008233

sp|O88643|PAK1_MOUSE
Serine/threonine-protein kinase PAK 1
Search

PAK1

0.88	LOW QUALITY PROTEIN: serine/threonine-protein kinase PAK 1

0.63	GO:0006468	protein phosphorylation
0.58	GO:0060244	negative regulation of cell proliferation involved in contact inhibition
0.57	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
0.57	GO:0048012	hepatocyte growth factor receptor signaling pathway
0.56	GO:0043406	positive regulation of MAP kinase activity
0.56	GO:0051496	positive regulation of stress fiber assembly
0.55	GO:0031116	positive regulation of microtubule polymerization
0.55	GO:0043506	regulation of JUN kinase activity
0.55	GO:0042981	regulation of apoptotic process
0.55	GO:0033138	positive regulation of peptidyl-serine phosphorylation

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0005518	collagen binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0048365	Rac GTPase binding
0.45	GO:0004708	MAP kinase kinase activity
0.39	GO:0042802	identical protein binding
0.38	GO:0017124	SH3 domain binding

0.56	GO:0071437	invadopodium
0.54	GO:0001726	ruffle
0.51	GO:0005911	cell-cell junction
0.48	GO:0005829	cytosol
0.43	GO:0043234	protein complex
0.42	GO:0005886	plasma membrane
0.39	GO:0005925	focal adhesion
0.39	GO:0120038	plasma membrane bounded cell projection part
0.39	GO:0097447	dendritic tree
0.38	GO:0030424	axon

0.70

GO:0004674

sp|O88653|LTOR3_MOUSE
Ragulator complex protein LAMTOR3
Search

LAMTOR3

0.97	Mitogen-activated protein kinase kinase 1-interacting protein 1

0.80	GO:0032006	regulation of TOR signaling
0.56	GO:0071230	cellular response to amino acid stimulus
0.52	GO:1902533	positive regulation of intracellular signal transduction
0.50	GO:0043405	regulation of MAP kinase activity
0.50	GO:0032147	activation of protein kinase activity
0.50	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.48	GO:0034613	cellular protein localization
0.42	GO:0016310	phosphorylation
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0030433	ubiquitin-dependent ERAD pathway

0.54	GO:0032947	protein complex scaffold activity
0.52	GO:0005085	guanyl-nucleotide exchange factor activity
0.51	GO:0019209	kinase activator activity
0.43	GO:0016301	kinase activity
0.35	GO:0031625	ubiquitin protein ligase binding
0.34	GO:0046982	protein heterodimerization activity
0.32	GO:0003677	DNA binding

0.56	GO:0071986	Ragulator complex
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0035579	specific granule membrane
0.35	GO:0070821	tertiary granule membrane
0.34	GO:0005765	lysosomal membrane
0.34	GO:0000786	nucleosome
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane

sp|O88662|EMP2_MOUSE
Epithelial membrane protein 2
Search

EMP2

0.97	Epithelial membrane protein 2

0.63	GO:0032060	bleb assembly
0.62	GO:0003093	regulation of glomerular filtration
0.59	GO:0001913	T cell mediated cytotoxicity
0.59	GO:2001212	regulation of vasculogenesis
0.59	GO:2001046	positive regulation of integrin-mediated signaling pathway
0.58	GO:0043534	blood vessel endothelial cell migration
0.58	GO:0034394	protein localization to cell surface
0.57	GO:0045022	early endosome to late endosome transport
0.57	GO:0070252	actin-mediated cell contraction
0.57	GO:0001765	membrane raft assembly

0.55	GO:0005178	integrin binding
0.52	GO:0019901	protein kinase binding

0.54	GO:0016324	apical plasma membrane
0.54	GO:0045121	membrane raft
0.51	GO:0009986	cell surface
0.50	GO:0031410	cytoplasmic vesicle
0.50	GO:0005794	Golgi apparatus
0.48	GO:0005829	cytosol
0.38	GO:0098588	bounding membrane of organelle
0.38	GO:0031984	organelle subcompartment
0.37	GO:0005634	nucleus
0.37	GO:0043218	compact myelin

sp|O88665|BRD7_MOUSE
Bromodomain-containing protein 7
Search

BRD7

0.95	Bromodomain-containing protein 7

0.85	GO:0035066	positive regulation of histone acetylation
0.84	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.78	GO:0008285	negative regulation of cell proliferation
0.73	GO:0045893	positive regulation of transcription, DNA-templated
0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.69	GO:0006357	regulation of transcription by RNA polymerase II
0.48	GO:0016055	Wnt signaling pathway
0.44	GO:0007049	cell cycle
0.41	GO:1901796	regulation of signal transduction by p53 class mediator
0.41	GO:0006351	transcription, DNA-templated

0.84	GO:0002039	p53 binding
0.84	GO:0070577	lysine-acetylated histone binding
0.81	GO:0003714	transcription corepressor activity
0.79	GO:0003713	transcription coactivator activity
0.74	GO:0044212	transcription regulatory region DNA binding
0.71	GO:0008134	transcription factor binding

0.68	GO:0005654	nucleoplasm
0.67	GO:0005829	cytosol

sp|O88667|RAD_MOUSE
GTP-binding protein RAD
Search

RRAD

0.96	GTP-binding protein RAD

0.86	GO:1901841	regulation of high voltage-gated calcium channel activity
0.81	GO:1901386	negative regulation of voltage-gated calcium channel activity
0.61	GO:0007165	signal transduction
0.46	GO:0051310	metaphase plate congression
0.43	GO:0000278	mitotic cell cycle
0.41	GO:0051276	chromosome organization
0.36	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.36	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.35	GO:0030308	negative regulation of cell growth
0.33	GO:0006955	immune response

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0005246	calcium channel regulator activity
0.40	GO:0000287	magnesium ion binding
0.38	GO:0005516	calmodulin binding
0.35	GO:0005509	calcium ion binding

0.46	GO:0051233	spindle midzone
0.45	GO:0030496	midbody
0.45	GO:0072686	mitotic spindle
0.43	GO:0009898	cytoplasmic side of plasma membrane
0.39	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|O88668|CREG1_MOUSE
Protein CREG1
Search

CREG1

0.97	Cellular repressor of E1A stimulated genes 1

0.44	GO:1903506	regulation of nucleic acid-templated transcription
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.38	GO:0040008	regulation of growth
0.36	GO:0043312	neutrophil degranulation
0.35	GO:0008283	cell proliferation
0.34	GO:1902679	negative regulation of RNA biosynthetic process
0.34	GO:0007275	multicellular organism development

0.56	GO:0048037	cofactor binding
0.52	GO:0008134	transcription factor binding
0.35	GO:0003714	transcription corepressor activity

0.53	GO:0005667	transcription factor complex
0.52	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.37	GO:0035578	azurophil granule lumen
0.30	GO:0031224	intrinsic component of membrane

sp|O88673|DGKA_MOUSE
Diacylglycerol kinase alpha
Search

0.48	Diacylglycerol kinase alpha

0.83	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.62	GO:0035556	intracellular signal transduction
0.57	GO:0016310	phosphorylation
0.55	GO:0046339	diacylglycerol metabolic process
0.51	GO:0006654	phosphatidic acid biosynthetic process
0.51	GO:0030258	lipid modification
0.36	GO:0030168	platelet activation
0.36	GO:0048666	neuron development

0.80	GO:0004143	diacylglycerol kinase activity
0.75	GO:0003951	NAD+ kinase activity
0.69	GO:0005509	calcium ion binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0005543	phospholipid binding

0.46	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane

0.80	EC:2.7.1.107	GO:0004143
0.75	KEGG:R00104	GO:0003951

sp|O88676|MMP23_MOUSE
Matrix metalloproteinase-23
Search

MMP23B

0.97	Matrix metalloproteinase-23

0.61	GO:0006508	proteolysis
0.47	GO:0000003	reproduction
0.40	GO:0001889	liver development
0.36	GO:0016567	protein ubiquitination
0.32	GO:0034769	basement membrane disassembly
0.32	GO:0006886	intracellular protein transport
0.32	GO:0016192	vesicle-mediated transport

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.36	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0016874	ligase activity
0.32	GO:0016887	ATPase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.74	GO:0031012	extracellular matrix
0.38	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0030131	clathrin adaptor complex
0.32	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

0.70	EC:3.4.24	GO:0004222
0.36	KEGG:R03876	GO:0004842

sp|O88685|PRS6A_MOUSE
26S protease regulatory subunit 6A
Search

PSMC3

0.78	Testicular secretory protein Li 42

0.81	GO:1901800	positive regulation of proteasomal protein catabolic process
0.70	GO:0030163	protein catabolic process
0.53	GO:0052472	modulation by host of symbiont transcription
0.52	GO:0006508	proteolysis
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:0046782	regulation of viral transcription
0.49	GO:0001824	blastocyst development
0.48	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.47	GO:2000144	positive regulation of DNA-templated transcription, initiation
0.46	GO:0034976	response to endoplasmic reticulum stress

0.82	GO:0036402	proteasome-activating ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0008233	peptidase activity
0.47	GO:0042802	identical protein binding
0.46	GO:0017025	TBP-class protein binding
0.37	GO:0033130	acetylcholine receptor binding
0.37	GO:0043495	protein membrane anchor

0.55	GO:1905369	endopeptidase complex
0.50	GO:0000932	P-body
0.47	GO:0043234	protein complex
0.44	GO:0005634	nucleus
0.43	GO:0044445	cytosolic part
0.42	GO:0070013	intracellular organelle lumen
0.39	GO:0044446	intracellular organelle part
0.35	GO:0045202	synapse
0.35	GO:0101002	ficolin-1-rich granule
0.35	GO:0031983	vesicle lumen

0.50

GO:0008233

sp|O88689|PCDA4_MOUSE
Protocadherin alpha-4
Search

0.91	Protocadherin alpha

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.53	GO:0007267	cell-cell signaling
0.53	GO:0007399	nervous system development
0.39	GO:0009988	cell-cell recognition
0.38	GO:0042476	odontogenesis
0.37	GO:0007283	spermatogenesis

0.70	GO:0005509	calcium ion binding
0.41	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.43	GO:0005783	endoplasmic reticulum
0.38	GO:0045202	synapse
0.37	GO:0005634	nucleus
0.37	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|O88693|CEGT_MOUSE
Ceramide glucosyltransferase
Search

UGCG

0.74	UDP-glucose ceramide glucosyltransferase

0.56	GO:1903955	positive regulation of protein targeting to mitochondrion
0.54	GO:0006687	glycosphingolipid metabolic process
0.50	GO:0046513	ceramide biosynthetic process
0.45	GO:0009247	glycolipid biosynthetic process
0.38	GO:0019377	glycolipid catabolic process
0.38	GO:0030149	sphingolipid catabolic process
0.37	GO:0048856	anatomical structure development
0.36	GO:0032501	multicellular organismal process

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.34	GO:0003677	DNA binding

0.39	GO:0000139	Golgi membrane
0.36	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.65

GO:0016757

sp|O88696|CLPP_MOUSE
ATP-dependent Clp protease proteolytic subunit, mitochondrial
Search

CLPP

0.42	ATP-dependent Clp protease proteolytic subunit

0.61	GO:0006508	proteolysis
0.46	GO:0044257	cellular protein catabolic process
0.37	GO:0051260	protein homooligomerization

0.69	GO:0004252	serine-type endopeptidase activity
0.37	GO:0042802	identical protein binding

0.54	GO:0009368	endopeptidase Clp complex
0.48	GO:0005759	mitochondrial matrix

0.69

GO:0004252

sp|O88697|STK16_MOUSE
Serine/threonine-protein kinase 16
Search

STK16

0.92	Serine/threonine-protein kinase 16

0.63	GO:0006468	protein phosphorylation
0.47	GO:0071560	cellular response to transforming growth factor beta stimulus
0.41	GO:0045793	positive regulation of cell size
0.39	GO:0006366	transcription by RNA polymerase II
0.39	GO:0045944	positive regulation of transcription by RNA polymerase II
0.38	GO:0018212	peptidyl-tyrosine modification
0.34	GO:0006413	translational initiation

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0003743	translation initiation factor activity
0.33	GO:0005515	protein binding

0.52	GO:0005798	Golgi-associated vesicle
0.48	GO:0005829	cytosol
0.38	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016020	membrane

sp|O88700|BLM_MOUSE
Bloom syndrome protein homolog
Search

BLM

0.91	Bloom syndrome RecQ like helicase

0.69	GO:0032508	DNA duplex unwinding
0.66	GO:0006260	DNA replication
0.65	GO:0006310	DNA recombination
0.64	GO:0006281	DNA repair
0.62	GO:0072757	cellular response to camptothecin
0.61	GO:0061820	telomeric D-loop disassembly
0.61	GO:0072711	cellular response to hydroxyurea
0.61	GO:0035786	protein complex oligomerization
0.60	GO:0044806	G-quadruplex DNA unwinding
0.60	GO:0010165	response to X-ray

0.79	GO:0043140	ATP-dependent 3'-5' DNA helicase activity
0.63	GO:0061749	forked DNA-dependent helicase activity
0.62	GO:1905773	8-hydroxy-2'-deoxyguanosine DNA binding
0.62	GO:0061821	telomeric D-loop binding
0.60	GO:0000405	bubble DNA binding
0.60	GO:0051880	G-quadruplex DNA binding
0.60	GO:0036310	annealing helicase activity
0.60	GO:0000403	Y-form DNA binding
0.59	GO:0000400	four-way junction DNA binding
0.58	GO:0002039	p53 binding

0.60	GO:0005634	nucleus
0.55	GO:0000781	chromosome, telomeric region
0.54	GO:0000793	condensed chromosome
0.49	GO:0005829	cytosol
0.49	GO:0070013	intracellular organelle lumen
0.39	GO:0005657	replication fork
0.30	GO:0016020	membrane

0.34

GO:0004674

sp|O88703|HCN2_MOUSE
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Search

0.85	Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2

0.72	GO:0071805	potassium ion transmembrane transport
0.69	GO:0034765	regulation of ion transmembrane transport
0.64	GO:0002027	regulation of heart rate
0.64	GO:0006814	sodium ion transport
0.60	GO:0071320	cellular response to cAMP
0.58	GO:0071321	cellular response to cGMP
0.57	GO:0042391	regulation of membrane potential
0.55	GO:0098659	inorganic cation import across plasma membrane
0.47	GO:0086018	SA node cell to atrial cardiac muscle cell signaling
0.46	GO:0046549	retinal cone cell development

0.77	GO:0005249	voltage-gated potassium channel activity
0.70	GO:0030552	cAMP binding
0.63	GO:0005222	intracellular cAMP activated cation channel activity
0.58	GO:0005248	voltage-gated sodium channel activity
0.53	GO:0042802	identical protein binding
0.36	GO:0032403	protein complex binding
0.36	GO:0030165	PDZ domain binding
0.35	GO:0032947	protein complex scaffold activity
0.35	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.34	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding

0.63	GO:0098855	HCN channel complex
0.45	GO:0030424	axon
0.45	GO:0036477	somatodendritic compartment
0.44	GO:0120038	plasma membrane bounded cell projection part
0.44	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0044297	cell body
0.37	GO:0098590	plasma membrane region
0.37	GO:0031256	leading edge membrane
0.37	GO:0045202	synapse
0.34	GO:0009986	cell surface

0.34

GO:0004252

sp|O88704|HCN1_MOUSE
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
Search

0.79	Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2

0.73	GO:0071805	potassium ion transmembrane transport
0.70	GO:0034765	regulation of ion transmembrane transport
0.70	GO:0006814	sodium ion transport
0.65	GO:0002027	regulation of heart rate
0.57	GO:0071320	cellular response to cAMP
0.55	GO:0042391	regulation of membrane potential
0.52	GO:0071321	cellular response to cGMP
0.52	GO:0007423	sensory organ development
0.51	GO:0048666	neuron development
0.50	GO:0098659	inorganic cation import across plasma membrane

0.80	GO:0030552	cAMP binding
0.78	GO:0005249	voltage-gated potassium channel activity
0.60	GO:0005222	intracellular cAMP activated cation channel activity
0.56	GO:0005248	voltage-gated sodium channel activity
0.51	GO:0042802	identical protein binding
0.38	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.38	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.37	GO:0008022	protein C-terminus binding
0.36	GO:0032403	protein complex binding
0.33	GO:0005524	ATP binding

0.60	GO:0098855	HCN channel complex
0.47	GO:0030424	axon
0.47	GO:0036477	somatodendritic compartment
0.45	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0120038	plasma membrane bounded cell projection part
0.39	GO:0016323	basolateral plasma membrane
0.39	GO:0044297	cell body
0.38	GO:0098793	presynapse
0.38	GO:0031256	leading edge membrane
0.36	GO:0009986	cell surface

sp|O88705|HCN3_MOUSE
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
Search

HCN3

0.89	Hyperpolarization activated cyclic nucleotide-gated potassium channel

0.72	GO:0071805	potassium ion transmembrane transport
0.71	GO:0002027	regulation of heart rate
0.70	GO:0034765	regulation of ion transmembrane transport
0.68	GO:0006814	sodium ion transport
0.59	GO:0042391	regulation of membrane potential
0.53	GO:0071320	cellular response to cAMP
0.53	GO:0071321	cellular response to cGMP
0.52	GO:0086018	SA node cell to atrial cardiac muscle cell signaling
0.51	GO:0086004	regulation of cardiac muscle cell contraction
0.50	GO:0098659	inorganic cation import across plasma membrane

0.76	GO:0005249	voltage-gated potassium channel activity
0.74	GO:0030552	cAMP binding
0.62	GO:0005248	voltage-gated sodium channel activity
0.55	GO:0005222	intracellular cAMP activated cation channel activity
0.46	GO:0042802	identical protein binding

0.54	GO:0005887	integral component of plasma membrane
0.48	GO:0034705	potassium channel complex
0.48	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0044316	cone cell pedicle
0.40	GO:0030424	axon
0.40	GO:0036477	somatodendritic compartment
0.39	GO:0044297	cell body
0.34	GO:0016323	basolateral plasma membrane

sp|O88708|ORC4_MOUSE
Origin recognition complex subunit 4
Search

ORC4

0.85	Origin recognition complex subunit 4

0.65	GO:0006260	DNA replication
0.35	GO:0000082	G1/S transition of mitotic cell cycle

0.57	GO:0003688	DNA replication origin binding
0.44	GO:0000166	nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.80	GO:0000808	origin recognition complex
0.60	GO:0005634	nucleus
0.57	GO:0000781	chromosome, telomeric region
0.51	GO:0031974	membrane-enclosed lumen
0.51	GO:0005829	cytosol

sp|O88712|CTBP1_MOUSE
C-terminal-binding protein 1
Search

CTBP1

0.96	C-terminal-binding protein 1

0.56	GO:1903756	regulation of transcription from RNA polymerase II promoter by histone modification
0.55	GO:0090241	negative regulation of histone H4 acetylation
0.54	GO:0050872	white fat cell differentiation
0.54	GO:0031065	positive regulation of histone deacetylation
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0000122	negative regulation of transcription by RNA polymerase II
0.47	GO:0051726	regulation of cell cycle
0.35	GO:0099526	presynapse to nucleus signaling pathway
0.34	GO:0008285	negative regulation of cell proliferation
0.34	GO:0006351	transcription, DNA-templated

0.68	GO:0051287	NAD binding
0.66	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.53	GO:0001106	RNA polymerase II transcription corepressor activity
0.52	GO:0070491	repressing transcription factor binding
0.49	GO:0019904	protein domain specific binding
0.44	GO:0042803	protein homodimerization activity
0.42	GO:0003700	DNA binding transcription factor activity
0.34	GO:0008022	protein C-terminus binding
0.33	GO:0016746	transferase activity, transferring acyl groups

0.51	GO:0017053	transcriptional repressor complex
0.48	GO:0005667	transcription factor complex
0.46	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol
0.34	GO:0098793	presynapse

0.66

EC:1.1.1

GO:0016616

sp|O88713|KLRG1_MOUSE
Killer cell lectin-like receptor subfamily G member 1
Search

KLRG1

0.97	Killer cell lectin like receptor G1

0.47	GO:0045087	innate immune response
0.42	GO:0007166	cell surface receptor signaling pathway
0.41	GO:0006968	cellular defense response
0.39	GO:0006954	inflammatory response
0.37	GO:0010951	negative regulation of endopeptidase activity

0.69	GO:0030246	carbohydrate binding
0.37	GO:0004866	endopeptidase inhibitor activity
0.36	GO:0004872	receptor activity
0.36	GO:0005515	protein binding

0.47	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0005886	plasma membrane
0.37	GO:0005615	extracellular space
0.30	GO:0044425	membrane part

sp|O88721|V2R_MOUSE
Vasopressin V2 receptor
Search

AVPR2

0.97	Vasopressin V2 receptor

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.57	GO:0032609	interferon-gamma production
0.55	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.52	GO:0034097	response to cytokine
0.50	GO:0001992	regulation of systemic arterial blood pressure by vasopressin
0.49	GO:0045907	positive regulation of vasoconstriction
0.47	GO:1901652	response to peptide
0.45	GO:0032870	cellular response to hormone stimulus
0.43	GO:0035814	negative regulation of renal sodium excretion
0.43	GO:0035811	negative regulation of urine volume

0.85	GO:0005000	vasopressin receptor activity
0.46	GO:0042277	peptide binding
0.36	GO:0042562	hormone binding
0.33	GO:0005515	protein binding

0.48	GO:0005886	plasma membrane
0.37	GO:0005622	intracellular
0.35	GO:0012506	vesicle membrane
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0012505	endomembrane system
0.30	GO:0016021	integral component of membrane

sp|O88728|IFM5_MOUSE
Interferon-induced transmembrane protein 5
Search

IFITM5

0.81	Interferon inducible transmembrane protein 5

0.70	GO:0009607	response to biotic stimulus
0.66	GO:0030282	bone mineralization
0.64	GO:0060349	bone morphogenesis
0.58	GO:0001701	in utero embryonic development
0.40	GO:0030500	regulation of bone mineralization

0.53

GO:0005887

integral component of plasma membrane

sp|O88735|MAP7_MOUSE
Ensconsin
Search

MAP7

0.96	Microtubule-associated protein 7

0.76	GO:0000226	microtubule cytoskeleton organization
0.41	GO:0033327	Leydig cell differentiation
0.41	GO:0060009	Sertoli cell development
0.40	GO:0032526	response to retinoic acid
0.40	GO:0035265	organ growth
0.40	GO:0006687	glycosphingolipid metabolic process
0.40	GO:0072659	protein localization to plasma membrane
0.40	GO:0009566	fertilization
0.40	GO:0006997	nucleus organization
0.39	GO:0007283	spermatogenesis

0.40	GO:0005198	structural molecule activity
0.38	GO:0005102	receptor binding
0.36	GO:0004709	MAP kinase kinase kinase activity
0.35	GO:0019903	protein phosphatase binding
0.35	GO:0019901	protein kinase binding
0.35	GO:0019904	protein domain specific binding
0.35	GO:0042803	protein homodimerization activity
0.34	GO:0000287	magnesium ion binding
0.33	GO:0003723	RNA binding
0.33	GO:0030554	adenyl nucleotide binding

0.71	GO:0015630	microtubule cytoskeleton
0.46	GO:0005829	cytosol
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0016323	basolateral plasma membrane
0.36	GO:0099513	polymeric cytoskeletal fiber
0.36	GO:1990604	IRE1-TRAF2-ASK1 complex
0.35	GO:1902911	protein kinase complex

0.36

EC:2.7.11 EC:2.7.11.25

GO:0004709

sp|O88736|DHB7_MOUSE
3-keto-steroid reductase
Search

HSD17B7

0.86	17-beta hydroxysteroid dehydrogenase

0.60	GO:0006695	cholesterol biosynthetic process
0.42	GO:0055114	oxidation-reduction process
0.41	GO:0006703	estrogen biosynthetic process
0.39	GO:0016310	phosphorylation
0.38	GO:1990637	response to prolactin
0.37	GO:0060135	maternal process involved in female pregnancy
0.36	GO:0032355	response to estradiol
0.36	GO:0021766	hippocampus development
0.36	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.35	GO:0018212	peptidyl-tyrosine modification

0.63	GO:0000253	3-keto sterol reductase activity
0.41	GO:0004303	estradiol 17-beta-dehydrogenase activity
0.39	GO:0016301	kinase activity
0.37	GO:0005148	prolactin receptor binding
0.36	GO:0038064	collagen receptor activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0005783	endoplasmic reticulum
0.36	GO:0005886	plasma membrane
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.63

EC:1.1.1.270

GO:0000253

sp|O88737|BSN_MOUSE
Protein bassoon
Search

BSN

0.97	Bassoon presynaptic cytomatrix protein

0.85	GO:0007416	synapse assembly
0.71	GO:0099526	presynapse to nucleus signaling pathway
0.67	GO:0035418	protein localization to synapse
0.41	GO:0048790	maintenance of presynaptic active zone structure
0.39	GO:0008090	retrograde axonal transport
0.37	GO:0007268	chemical synaptic transmission
0.37	GO:0006508	proteolysis
0.37	GO:0007010	cytoskeleton organization
0.32	GO:0030073	insulin secretion
0.31	GO:0019933	cAMP-mediated signaling

0.52	GO:0046872	metal ion binding
0.42	GO:0098882	structural constituent of presynaptic active zone
0.40	GO:0001222	transcription corepressor binding
0.39	GO:0045503	dynein light chain binding
0.38	GO:0017171	serine hydrolase activity
0.37	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.32	GO:0005522	profilin binding

0.83	GO:0048786	presynaptic active zone
0.64	GO:0044306	neuron projection terminus
0.64	GO:0014069	postsynaptic density
0.63	GO:0099738	cell cortex region
0.62	GO:0030425	dendrite
0.61	GO:0030424	axon
0.59	GO:0009986	cell surface
0.46	GO:0060076	excitatory synapse
0.43	GO:0099569	presynaptic cytoskeleton
0.42	GO:0030054	cell junction

sp|O88738|BIRC6_MOUSE
Baculoviral IAP repeat-containing protein 6
Search

BIRC6

0.94	Baculoviral IAP repeat-containing protein 6

0.77	GO:0032465	regulation of cytokinesis
0.76	GO:0006915	apoptotic process
0.72	GO:0016567	protein ubiquitination
0.57	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.57	GO:0060712	spongiotrophoblast layer development
0.55	GO:0060711	labyrinthine layer development
0.53	GO:0008284	positive regulation of cell proliferation
0.53	GO:0010951	negative regulation of endopeptidase activity
0.36	GO:0015031	protein transport
0.35	GO:0051301	cell division

0.72	GO:0004842	ubiquitin-protein transferase activity
0.57	GO:0061650	ubiquitin-like protein conjugating enzyme activity
0.56	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.35	GO:0005515	protein binding
0.34	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.33	GO:0140101	catalytic activity, acting on a tRNA
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0030496	midbody
0.54	GO:0005802	trans-Golgi network
0.54	GO:0000922	spindle pole
0.52	GO:0005815	microtubule organizing center
0.52	GO:0005768	endosome
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:6.1	GO:0016875
0.72	KEGG:R03876	GO:0004842

sp|O88741|GDAP1_MOUSE
Ganglioside-induced differentiation-associated protein 1
Search

GDAP1

0.88	Ganglioside-induced differentiation-associated protein 1

0.47	GO:0032526	response to retinoic acid
0.46	GO:0008053	mitochondrial fusion
0.46	GO:0000266	mitochondrial fission
0.45	GO:0006626	protein targeting to mitochondrion
0.44	GO:0006749	glutathione metabolic process
0.41	GO:0071305	cellular response to vitamin D

0.45

GO:0004364

glutathione transferase activity

0.46	GO:0031307	integral component of mitochondrial outer membrane
0.42	GO:0005829	cytosol
0.35	GO:0005634	nucleus

0.45

EC:2.5.1.18

GO:0004364

sp|O88745|SCRG1_MOUSE
Scrapie-responsive protein 1
Search

sp|O88746|TOM1_MOUSE
Target of Myb protein 1
Search

TOM1

0.92	Target of Myb protein 1

0.65	GO:0006886	intracellular protein transport
0.40	GO:0045839	negative regulation of mitotic nuclear division
0.36	GO:0007165	signal transduction
0.36	GO:0043312	neutrophil degranulation
0.35	GO:0016197	endosomal transport
0.34	GO:0006897	endocytosis

0.55	GO:0030276	clathrin binding
0.40	GO:0019901	protein kinase binding

0.53	GO:0005769	early endosome
0.48	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.36	GO:0035579	specific granule membrane
0.36	GO:0035577	azurophil granule membrane
0.33	GO:0005886	plasma membrane

sp|O88783|FA5_MOUSE
Coagulation factor V
Search

0.67	Coagulation factor V

0.71	GO:0007596	blood coagulation
0.63	GO:0008015	blood circulation
0.47	GO:0032571	response to vitamin K
0.44	GO:0072376	protein activation cascade
0.39	GO:0055114	oxidation-reduction process
0.38	GO:0009617	response to bacterium
0.37	GO:0001775	cell activation
0.34	GO:0002576	platelet degranulation
0.33	GO:0048208	COPII vesicle coating
0.33	GO:0035807	positive regulation of blood coagulation in other organism

0.71	GO:0005507	copper ion binding
0.39	GO:0016491	oxidoreductase activity
0.33	GO:0016504	peptidase activator activity
0.33	GO:0090729	toxin activity
0.33	GO:0005515	protein binding
0.32	GO:0004252	serine-type endopeptidase activity

0.68	GO:0031091	platelet alpha granule
0.58	GO:0005615	extracellular space
0.44	GO:1903561	extracellular vesicle
0.41	GO:0005794	Golgi apparatus
0.41	GO:0005783	endoplasmic reticulum
0.34	GO:0034774	secretory granule lumen
0.34	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.33	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.32	GO:0031984	organelle subcompartment
0.32	GO:0005886	plasma membrane

0.39

GO:0016491

sp|O88786|I13R2_MOUSE
Interleukin-13 receptor subunit alpha-2
Search

IL13RA2

0.96	Interleukin-13 receptor subunit alpha-2

0.75	GO:0019221	cytokine-mediated signaling pathway
0.72	GO:0043305	negative regulation of mast cell degranulation
0.71	GO:0002638	negative regulation of immunoglobulin production
0.66	GO:0016064	immunoglobulin mediated immune response
0.41	GO:0071260	cellular response to mechanical stimulus

0.77	GO:0004896	cytokine receptor activity
0.35	GO:0005515	protein binding

0.39	GO:0005576	extracellular region
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|O88792|JAM1_MOUSE
Junctional adhesion molecule A
Search

F11R

0.97	Junctional adhesion molecule A

0.61	GO:0090557	establishment of endothelial intestinal barrier
0.60	GO:0050892	intestinal absorption
0.59	GO:0034260	negative regulation of GTPase activity
0.59	GO:2000249	regulation of actin cytoskeleton reorganization
0.58	GO:0090559	regulation of membrane permeability
0.57	GO:0072659	protein localization to plasma membrane
0.56	GO:0031032	actomyosin structure organization
0.54	GO:0001817	regulation of cytokine production
0.53	GO:0043547	positive regulation of GTPase activity
0.51	GO:0007155	cell adhesion

0.58	GO:0030165	PDZ domain binding
0.56	GO:0045296	cadherin binding
0.37	GO:0046982	protein heterodimerization activity
0.36	GO:0104005	hijacked molecular function
0.33	GO:0004910	interleukin-1, Type II, blocking receptor activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0005070	SH3/SH2 adaptor activity
0.32	GO:0032555	purine ribonucleotide binding

0.56	GO:0005923	bicellular tight junction
0.43	GO:0036057	slit diaphragm
0.43	GO:0005886	plasma membrane
0.39	GO:0031410	cytoplasmic vesicle
0.38	GO:0070062	extracellular exosome
0.32	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

0.31

GO:0016740

sp|O88796|RPP30_MOUSE
Ribonuclease P protein subunit p30
Search

RPP30

0.94	Ribonuclease P protein subunit p30

0.67	GO:0090501	RNA phosphodiester bond hydrolysis
0.64	GO:0008033	tRNA processing
0.40	GO:0043043	peptide biosynthetic process
0.38	GO:0044267	cellular protein metabolic process
0.37	GO:0009059	macromolecule biosynthetic process
0.34	GO:0006364	rRNA processing

0.67	GO:0004540	ribonuclease activity
0.52	GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
0.49	GO:0140101	catalytic activity, acting on a tRNA
0.41	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.58	GO:0030681	multimeric ribonuclease P complex
0.57	GO:0000172	ribonuclease MRP complex
0.46	GO:0044452	nucleolar part
0.40	GO:0005840	ribosome
0.34	GO:0005654	nucleoplasm

0.52

EC:3.1.30

GO:0016893

sp|O88799|ZAN_MOUSE
Zonadhesin
Search

ZAN

0.52	LOW QUALITY PROTEIN: zonadhesin

0.57	GO:2000359	regulation of binding of sperm to zona pellucida
0.54	GO:0007339	binding of sperm to zona pellucida
0.48	GO:0007155	cell adhesion

0.53	GO:0050840	extracellular matrix binding
0.35	GO:0005509	calcium ion binding
0.33	GO:0005201	extracellular matrix structural constituent
0.32	GO:0005515	protein binding

0.41	GO:0005886	plasma membrane
0.33	GO:0044421	extracellular region part
0.32	GO:0031982	vesicle
0.30	GO:0044425	membrane part

sp|O88803|LECT2_MOUSE
Leukocyte cell-derived chemotaxin-2
Search

LECT2

0.96	Leukocyte cell-derived chemotaxin-2

0.46	GO:0030178	negative regulation of Wnt signaling pathway
0.44	GO:0006935	chemotaxis
0.40	GO:0001501	skeletal system development

0.74	GO:0042802	identical protein binding
0.38	GO:0046872	metal ion binding

0.43	GO:0005576	extracellular region
0.34	GO:0005737	cytoplasm

sp|O88809|DCX_MOUSE
Neuronal migration protein doublecortin
Search

DCX

0.97	Neuronal migration protein doublecortin

0.63	GO:0035556	intracellular signal transduction
0.58	GO:0021860	pyramidal neuron development
0.56	GO:0021819	layer formation in cerebral cortex
0.56	GO:0021766	hippocampus development
0.55	GO:0021952	central nervous system projection neuron axonogenesis
0.54	GO:0048675	axon extension
0.54	GO:0001764	neuron migration
0.54	GO:0048813	dendrite morphogenesis
0.43	GO:0006468	protein phosphorylation
0.40	GO:0018209	peptidyl-serine modification

0.44	GO:0004672	protein kinase activity
0.40	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0019901	protein kinase binding
0.36	GO:0008017	microtubule binding
0.36	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.33	GO:0005516	calmodulin binding
0.32	GO:0003677	DNA binding

0.51	GO:0043005	neuron projection
0.48	GO:0005829	cytosol
0.40	GO:0015630	microtubule cytoskeleton
0.39	GO:0099513	polymeric cytoskeletal fiber
0.34	GO:0043025	neuronal cell body
0.34	GO:0030427	site of polarized growth
0.34	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0005634	nucleus
0.33	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|O88811|STAM2_MOUSE
Signal transducing adapter molecule 2
Search

STAM2

0.97	Signal transducing adapter molecule 2

0.68	GO:0006886	intracellular protein transport
0.42	GO:1903551	regulation of extracellular exosome assembly
0.41	GO:1903543	positive regulation of exosomal secretion
0.35	GO:0036258	multivesicular body assembly
0.35	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.35	GO:0016236	macroautophagy
0.34	GO:0016197	endosomal transport
0.34	GO:0016579	protein deubiquitination
0.34	GO:0061024	membrane organization
0.33	GO:0007165	signal transduction

0.39	GO:0044389	ubiquitin-like protein ligase binding
0.34	GO:0017124	SH3 domain binding

0.48	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol
0.43	GO:0033565	ESCRT-0 complex
0.40	GO:0031901	early endosome membrane
0.34	GO:0030139	endocytic vesicle
0.30	GO:0016021	integral component of membrane

sp|O88816|SNAT_MOUSE
Serotonin N-acetyltransferase
Search

AANAT

0.94	Arylalkylamine-N-acetyl-transferase

0.63	GO:0030187	melatonin biosynthetic process
0.58	GO:0071320	cellular response to cAMP
0.58	GO:0007623	circadian rhythm
0.55	GO:0006474	N-terminal protein amino acid acetylation
0.46	GO:0009416	response to light stimulus
0.41	GO:0051412	response to corticosterone
0.40	GO:0034695	response to prostaglandin E
0.40	GO:0010043	response to zinc ion
0.40	GO:0051592	response to calcium ion
0.39	GO:0032868	response to insulin

0.69	GO:0004059	aralkylamine N-acetyltransferase activity
0.56	GO:0004060	arylamine N-acetyltransferase activity
0.40	GO:0071889	14-3-3 protein binding

0.54	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0005829	cytosol

0.69

EC:2.3.1.87

GO:0004059

sp|O88819|FUT9_MOUSE
Alpha-(1,3)-fucosyltransferase 9
Search

FUT9

0.74	Fucosyltransferase 9

0.81	GO:0036065	fucosylation
0.74	GO:0006486	protein glycosylation
0.38	GO:0007399	nervous system development
0.35	GO:0042355	L-fucose catabolic process

0.81

GO:0008417

fucosyltransferase activity

0.81	GO:0032580	Golgi cisterna membrane
0.30	GO:0016021	integral component of membrane

0.81

EC:2.4.1

GO:0008417

sp|O88822|SC5D_MOUSE
Lathosterol oxidase
Search

SC5D

0.93	Lathosterol oxidase

0.65	GO:0008610	lipid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.50	GO:1902653	secondary alcohol biosynthetic process
0.49	GO:0016125	sterol metabolic process
0.46	GO:0001878	response to yeast
0.41	GO:0044108	cellular alcohol biosynthetic process
0.41	GO:0016128	phytosteroid metabolic process
0.40	GO:1901362	organic cyclic compound biosynthetic process
0.38	GO:0044255	cellular lipid metabolic process
0.36	GO:0007605	sensory perception of sound

0.63	GO:0005506	iron ion binding
0.55	GO:0000248	C-5 sterol desaturase activity
0.52	GO:0050046	lathosterol oxidase activity
0.36	GO:0005201	extracellular matrix structural constituent
0.33	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.32	GO:0003723	RNA binding

0.47	GO:0044432	endoplasmic reticulum part
0.44	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.43	GO:0031984	organelle subcompartment
0.38	GO:0043233	organelle lumen
0.35	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

0.52

EC:1.14.21.6

GO:0050046

sp|O88824|JTB_MOUSE
Protein JTB
Search

JTB

0.97	Jumping translocation breakpoint

0.71	GO:0008637	apoptotic mitochondrial changes
0.68	GO:0000281	mitotic cytokinesis
0.66	GO:0045860	positive regulation of protein kinase activity
0.64	GO:0042127	regulation of cell proliferation

0.66

GO:0019901

protein kinase binding

0.69	GO:0030496	midbody
0.66	GO:0005813	centrosome
0.65	GO:0005819	spindle
0.52	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

sp|O88829|SIAT9_MOUSE
Lactosylceramide alpha-2,3-sialyltransferase
Search

ST3GAL5

0.95	Lactosylceramide alpha-2,3-sialyltransferase

0.82	GO:0097503	sialylation
0.73	GO:0006486	protein glycosylation
0.48	GO:0018196	peptidyl-asparagine modification
0.43	GO:0009311	oligosaccharide metabolic process
0.41	GO:0006688	glycosphingolipid biosynthetic process
0.36	GO:0001573	ganglioside metabolic process
0.35	GO:0046513	ceramide biosynthetic process
0.32	GO:0006351	transcription, DNA-templated

0.83	GO:0008373	sialyltransferase activity
0.35	GO:0004308	exo-alpha-sialidase activity
0.32	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0003677	DNA binding

0.68	GO:0005794	Golgi apparatus
0.43	GO:0098588	bounding membrane of organelle
0.42	GO:0031984	organelle subcompartment
0.34	GO:0005887	integral component of plasma membrane
0.32	GO:0005634	nucleus

0.83

EC:2.4.99

GO:0008373

sp|O88833|CP4AA_MOUSE
Cytochrome P450 4A10
Search

0.97	Fatty acid omega-hydroxylase

0.53	GO:0055114	oxidation-reduction process
0.46	GO:0006690	icosanoid metabolic process
0.46	GO:0033559	unsaturated fatty acid metabolic process
0.44	GO:0001676	long-chain fatty acid metabolic process
0.42	GO:1901569	fatty acid derivative catabolic process
0.41	GO:0048252	lauric acid metabolic process
0.41	GO:0009062	fatty acid catabolic process
0.40	GO:1901616	organic hydroxy compound catabolic process
0.39	GO:0001822	kidney development
0.38	GO:0003095	pressure natriuresis

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.64	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.44	GO:0103002	16-hydroxypalmitate dehydrogenase activity
0.35	GO:0050544	arachidonic acid binding
0.34	GO:0019825	oxygen binding

0.44	GO:0005789	endoplasmic reticulum membrane
0.42	GO:0016324	apical plasma membrane
0.40	GO:0005615	extracellular space
0.39	GO:0031090	organelle membrane
0.35	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

0.68

EC:1.14

GO:0016705

sp|O88834|SHD_MOUSE
SH2 domain-containing adapter protein D
Search

SHD

0.95	Src homology 2 domain containing transforming protein D

0.75	GO:0009967	positive regulation of signal transduction
0.60	GO:0007165	signal transduction

0.85

GO:0005070

SH3/SH2 adaptor activity

sp|O88838|SPSB2_MOUSE
SPRY domain-containing SOCS box protein 2
Search

0.89	SPRY domain-containing SOCS box protein 2

0.62	GO:0035556	intracellular signal transduction
0.57	GO:0016567	protein ubiquitination
0.39	GO:1900075	positive regulation of neuromuscular synaptic transmission
0.38	GO:0043687	post-translational protein modification
0.38	GO:0045887	positive regulation of synaptic growth at neuromuscular junction
0.38	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
0.38	GO:0040024	dauer larval development
0.38	GO:0048681	negative regulation of axon regeneration
0.38	GO:0030517	negative regulation of axon extension
0.37	GO:0008340	determination of adult lifespan

0.39	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0001882	nucleoside binding
0.32	GO:0003677	DNA binding

0.45	GO:0005622	intracellular
0.36	GO:0043005	neuron projection
0.34	GO:0045202	synapse
0.34	GO:0030054	cell junction
0.33	GO:1990904	ribonucleoprotein complex
0.33	GO:0043228	non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.33

GO:0003899

sp|O88839|ADA15_MOUSE
Disintegrin and metalloproteinase domain-containing protein 15
Search

ADAM15

0.85	LOW QUALITY PROTEIN: disintegrin and metalloproteinase domain-containing protein 15

0.71	GO:0007229	integrin-mediated signaling pathway
0.61	GO:0002418	immune response to tumor cell
0.61	GO:0006508	proteolysis
0.59	GO:0070528	protein kinase C signaling
0.59	GO:1900121	negative regulation of receptor binding
0.58	GO:0001953	negative regulation of cell-matrix adhesion
0.58	GO:0060317	cardiac epithelial to mesenchymal transition
0.56	GO:0030308	negative regulation of cell growth
0.55	GO:0030336	negative regulation of cell migration
0.54	GO:0045087	innate immune response

0.70	GO:0004222	metalloendopeptidase activity
0.61	GO:0017124	SH3 domain binding
0.57	GO:0005178	integrin binding
0.54	GO:0046872	metal ion binding
0.33	GO:0046875	ephrin receptor binding

0.55	GO:0070062	extracellular exosome
0.52	GO:0009986	cell surface
0.45	GO:0012505	endomembrane system
0.41	GO:0097223	sperm part
0.40	GO:0044444	cytoplasmic part
0.40	GO:0043231	intracellular membrane-bounded organelle
0.40	GO:0005912	adherens junction
0.39	GO:0097708	intracellular vesicle
0.38	GO:0042995	cell projection
0.35	GO:0043233	organelle lumen

0.70

GO:0004222

sp|O88842|FGD3_MOUSE
FYVE, RhoGEF and PH domain-containing protein 3
Search

FGD3

0.97	FYVE, RhoGEF and PH domain-containing protein 3

0.76	GO:0035023	regulation of Rho protein signal transduction
0.65	GO:0065009	regulation of molecular function
0.50	GO:0046847	filopodium assembly
0.43	GO:0030036	actin cytoskeleton organization
0.42	GO:0008360	regulation of cell shape
0.34	GO:0043065	positive regulation of apoptotic process
0.34	GO:0009887	animal organ morphogenesis
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.52	GO:0046872	metal ion binding

0.46	GO:0001726	ruffle
0.46	GO:0030027	lamellipodium
0.42	GO:0005794	Golgi apparatus
0.36	GO:0005856	cytoskeleton
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|O88843|CRADD_MOUSE
Death domain-containing protein CRADD
Search

CRADD

0.89	Death domain-containing protein CRADD

0.73	GO:0042981	regulation of apoptotic process
0.56	GO:0007165	signal transduction
0.48	GO:0071158	positive regulation of cell cycle arrest
0.48	GO:0031571	mitotic G1 DNA damage checkpoint
0.48	GO:0071260	cellular response to mechanical stimulus
0.46	GO:2001056	positive regulation of cysteine-type endopeptidase activity
0.45	GO:0043068	positive regulation of programmed cell death
0.43	GO:0009967	positive regulation of signal transduction
0.42	GO:0006915	apoptotic process
0.37	GO:0046426	negative regulation of JAK-STAT cascade

0.86	GO:0070513	death domain binding
0.82	GO:0002020	protease binding
0.47	GO:0030674	protein binding, bridging
0.38	GO:0005159	insulin-like growth factor receptor binding
0.37	GO:0035591	signaling adaptor activity

0.39	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm

sp|O88844|IDHC_MOUSE
Isocitrate dehydrogenase [NADP] cytoplasmic
Search

IDH1

0.49	Isocitrate dehydrogenase [NADP] cytoplasmic

0.81	GO:0006102	isocitrate metabolic process
0.60	GO:0006099	tricarboxylic acid cycle
0.53	GO:0006103	2-oxoglutarate metabolic process
0.53	GO:0060696	regulation of phospholipid catabolic process
0.51	GO:0071071	regulation of phospholipid biosynthetic process
0.47	GO:0006749	glutathione metabolic process
0.46	GO:0006979	response to oxidative stress
0.41	GO:0048513	animal organ development
0.41	GO:0006097	glyoxylate cycle
0.40	GO:0002520	immune system development

0.78	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.67	GO:0051287	NAD binding
0.64	GO:0000287	magnesium ion binding
0.52	GO:0045296	cadherin binding
0.50	GO:0042803	protein homodimerization activity
0.48	GO:0005102	receptor binding
0.39	GO:0051990	(R)-2-hydroxyglutarate dehydrogenase activity
0.36	GO:0050661	NADP binding

0.50	GO:0005777	peroxisome
0.47	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.35	GO:1904724	tertiary granule lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.35	GO:0031907	microbody lumen

0.78

EC:1.1.1.42

GO:0004450

sp|O88845|AKA10_MOUSE
A-kinase anchor protein 10, mitochondrial
Search

AKAP10

0.95	A-kinase-anchoring protein 10

0.60

GO:0008104

protein localization

0.85

GO:0051018

protein kinase A binding

0.66	GO:0005829	cytosol
0.57	GO:0043234	protein complex
0.57	GO:0005739	mitochondrion
0.54	GO:0005886	plasma membrane

sp|O88848|ARL6_MOUSE
ADP-ribosylation factor-like protein 6
Search

ARL6

0.96	ADP ribosylation factor like GTPase 6

0.55	GO:1903445	protein transport from ciliary membrane to plasma membrane
0.54	GO:0097499	protein localization to non-motile cilium
0.53	GO:0010842	retina layer formation
0.52	GO:0060271	cilium assembly
0.52	GO:0008589	regulation of smoothened signaling pathway
0.52	GO:0045444	fat cell differentiation
0.50	GO:0016055	Wnt signaling pathway
0.50	GO:0007420	brain development
0.41	GO:0032402	melanosome transport
0.40	GO:0007368	determination of left/right symmetry

0.62	GO:0032550	purine ribonucleoside binding
0.62	GO:0019001	guanyl nucleotide binding
0.52	GO:0032555	purine ribonucleotide binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0005543	phospholipid binding
0.34	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.50	GO:0005929	cilium
0.45	GO:0005829	cytosol
0.39	GO:0005881	cytoplasmic microtubule
0.39	GO:0031253	cell projection membrane
0.39	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.38	GO:0030117	membrane coat
0.37	GO:0098588	bounding membrane of organelle
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|O88851|RBBP9_MOUSE
Putative hydrolase RBBP9
Search

RBBP9

0.37	Retinoblastoma binding protein 9

0.40	GO:0042127	regulation of cell proliferation
0.35	GO:0009312	oligosaccharide biosynthetic process
0.34	GO:0006446	regulation of translational initiation
0.34	GO:0006413	translational initiation
0.32	GO:0006429	leucyl-tRNA aminoacylation
0.32	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity

0.51	GO:0016787	hydrolase activity
0.35	GO:0005515	protein binding
0.34	GO:0043022	ribosome binding
0.34	GO:0003743	translation initiation factor activity
0.32	GO:0004823	leucine-tRNA ligase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0005654	nucleoplasm
0.38	GO:0070062	extracellular exosome
0.34	GO:0005852	eukaryotic translation initiation factor 3 complex
0.34	GO:1905369	endopeptidase complex

0.51	EC:3	GO:0016787
0.32	KEGG:R03657	GO:0004823

sp|O88852|TSYL1_MOUSE
Testis-specific Y-encoded-like protein 1
Search

0.97	Testis-specific Y-encoded-like protein 1

0.79	GO:0006334	nucleosome assembly
0.41	GO:0071480	cellular response to gamma radiation
0.41	GO:0051897	positive regulation of protein kinase B signaling
0.40	GO:0031398	positive regulation of protein ubiquitination
0.40	GO:0008284	positive regulation of cell proliferation
0.33	GO:0040008	regulation of growth
0.33	GO:0016444	somatic cell DNA recombination
0.33	GO:0000724	double-strand break repair via homologous recombination

0.46

GO:0019899

enzyme binding

0.61	GO:0005634	nucleus
0.45	GO:0031974	membrane-enclosed lumen
0.42	GO:0043232	intracellular non-membrane-bounded organelle
0.41	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|O88853|GALR3_MOUSE
Galanin receptor type 3
Search

GALR3

0.94	Galanin receptor type 3

0.68	GO:0007186	G-protein coupled receptor signaling pathway
0.64	GO:0007194	negative regulation of adenylate cyclase activity
0.53	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:1902608	positive regulation of large conductance calcium-activated potassium channel activity
0.48	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.44	GO:0031175	neuron projection development
0.37	GO:0019933	cAMP-mediated signaling
0.37	GO:0007631	feeding behavior
0.37	GO:0007611	learning or memory
0.37	GO:0043647	inositol phosphate metabolic process

0.69	GO:0004930	G-protein coupled receptor activity
0.61	GO:0001653	peptide receptor activity
0.59	GO:0017046	peptide hormone binding
0.38	GO:0042923	neuropeptide binding
0.34	GO:0005230	extracellular ligand-gated ion channel activity
0.33	GO:0005515	protein binding

0.52	GO:0097730	non-motile cilium
0.43	GO:0005887	integral component of plasma membrane
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane

sp|O88854|GALR2_MOUSE
Galanin receptor type 2
Search

GALR2

0.94	Galanin receptor type 2

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.61	GO:0007194	negative regulation of adenylate cyclase activity
0.57	GO:1902608	positive regulation of large conductance calcium-activated potassium channel activity
0.56	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.50	GO:0031175	neuron projection development
0.39	GO:0019933	cAMP-mediated signaling
0.39	GO:0043647	inositol phosphate metabolic process
0.38	GO:0046488	phosphatidylinositol metabolic process
0.37	GO:0007631	feeding behavior

0.71	GO:0004930	G-protein coupled receptor activity
0.61	GO:0001653	peptide receptor activity
0.56	GO:0017046	peptide hormone binding
0.40	GO:0042923	neuropeptide binding
0.35	GO:0005230	extracellular ligand-gated ion channel activity
0.33	GO:0005515	protein binding

0.42	GO:0005887	integral component of plasma membrane
0.39	GO:0097730	non-motile cilium
0.33	GO:0005622	intracellular

sp|O88855|LT4R1_MOUSE
Leukotriene B4 receptor 1
Search

LTB4R

0.97	Leukotriene B4 receptor

0.85	GO:0061737	leukotriene signaling pathway
0.56	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.53	GO:0007218	neuropeptide signaling pathway
0.47	GO:0051546	keratinocyte migration
0.46	GO:0006954	inflammatory response
0.42	GO:0038178	complement component C5a signaling pathway
0.41	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.40	GO:0050679	positive regulation of epithelial cell proliferation
0.40	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.38	GO:0006935	chemotaxis

0.85	GO:0004974	leukotriene receptor activity
0.53	GO:0008528	G-protein coupled peptide receptor activity
0.42	GO:0004878	complement component C5a receptor activity
0.35	GO:0005515	protein binding
0.33	GO:1901265	nucleoside phosphate binding
0.33	GO:0036094	small molecule binding

0.48	GO:0005887	integral component of plasma membrane
0.44	GO:0045121	membrane raft
0.41	GO:0005654	nucleoplasm
0.38	GO:0009986	cell surface
0.37	GO:0009925	basal plasma membrane
0.36	GO:0045177	apical part of cell

sp|O88856|TPST2_MOUSE
Protein-tyrosine sulfotransferase 2
Search

TPST2

0.97	Tyrosylprotein sulfotransferase 2

0.84	GO:0006478	peptidyl-tyrosine sulfation
0.38	GO:0060468	prevention of polyspermy
0.37	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization
0.35	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process

0.84	GO:0008476	protein-tyrosine sulfotransferase activity
0.52	GO:0042803	protein homodimerization activity
0.32	GO:0003676	nucleic acid binding

0.50	GO:0012505	endomembrane system
0.44	GO:0043231	intracellular membrane-bounded organelle
0.43	GO:0044444	cytoplasmic part
0.41	GO:0098588	bounding membrane of organelle
0.41	GO:0031984	organelle subcompartment
0.39	GO:0031301	integral component of organelle membrane
0.36	GO:0070062	extracellular exosome

0.84

EC:2.8.2.20

GO:0008476

sp|O88866|HUNK_MOUSE
Hormonally up-regulated neu tumor-associated kinase
Search

HUNK

0.96	Hormonally up-regulated neu tumor-associated kinase

0.63	GO:0006468	protein phosphorylation
0.43	GO:0035556	intracellular signal transduction
0.35	GO:0007275	multicellular organism development

0.63	GO:0004672	protein kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.42	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|O88870|BEST1_MOUSE
Bestrophin-1
Search

BEST1

0.67	Bestrophin

0.77	GO:1902476	chloride transmembrane transport
0.70	GO:0007601	visual perception
0.55	GO:0043269	regulation of ion transport
0.55	GO:0030321	transepithelial chloride transport
0.55	GO:0050962	detection of light stimulus involved in sensory perception
0.51	GO:0009584	detection of visible light
0.47	GO:0051051	negative regulation of transport
0.35	GO:0015701	bicarbonate transport

0.78	GO:0005254	chloride channel activity
0.48	GO:0042802	identical protein binding
0.35	GO:0015106	bicarbonate transmembrane transporter activity
0.34	GO:0022839	ion gated channel activity
0.34	GO:0008381	mechanosensitive ion channel activity
0.32	GO:0046872	metal ion binding

0.81	GO:0034707	chloride channel complex
0.55	GO:0005886	plasma membrane
0.33	GO:0005829	cytosol

sp|O88874|CCNK_MOUSE
Cyclin-K
Search

CCNK

0.91

Cyclin-K

0.57	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain
0.56	GO:0044828	negative regulation by host of viral genome replication
0.56	GO:2001163	regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues
0.54	GO:0071157	negative regulation of cell cycle arrest
0.48	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0006974	cellular response to DNA damage stimulus
0.44	GO:0006468	protein phosphorylation
0.38	GO:2000737	negative regulation of stem cell differentiation
0.37	GO:0001701	in utero embryonic development

0.53	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.53	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.50	GO:0019901	protein kinase binding
0.47	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity

0.59	GO:0005634	nucleus
0.57	GO:0002944	cyclin K-CDK12 complex
0.57	GO:0002945	cyclin K-CDK13 complex
0.47	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.33	GO:0032993	protein-DNA complex
0.33	GO:0005694	chromosome
0.30	GO:0016020	membrane

0.53

EC:2.7.11.22

GO:0004693

sp|O88875|BY55_MOUSE
CD160 antigen
Search

sp|O88876|DHRS3_MOUSE
Short-chain dehydrogenase/reductase 3
Search

DHRS3

0.97	Short-chain dehydrogenase/reductase 3

0.84	GO:0042572	retinol metabolic process
0.58	GO:0048387	negative regulation of retinoic acid receptor signaling pathway
0.56	GO:0060411	cardiac septum morphogenesis
0.56	GO:0003151	outflow tract morphogenesis
0.55	GO:0060021	palate development
0.55	GO:0060349	bone morphogenesis
0.54	GO:0030278	regulation of ossification
0.52	GO:0055114	oxidation-reduction process
0.40	GO:0002138	retinoic acid biosynthetic process
0.36	GO:1900053	negative regulation of retinoic acid biosynthetic process

0.85	GO:0004745	retinol dehydrogenase activity
0.45	GO:0052650	NADP-retinol dehydrogenase activity
0.33	GO:0009055	electron transfer activity
0.33	GO:0003885	D-arabinono-1,4-lactone oxidase activity
0.33	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding
0.32	GO:0102131	3-oxo-glutaryl-[acp] methyl ester reductase activity
0.32	GO:0102132	3-oxo-pimeloyl-[acp] methyl ester reductase activity
0.32	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
0.32	GO:0047936	glucose 1-dehydrogenase [NAD(P)] activity

0.35	GO:0042622	photoreceptor outer segment membrane
0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.85	EC:1.1.1.105	GO:0004745
0.45	KEGG:R08379	GO:0052650

sp|O88878|ZFAN5_MOUSE
AN1-type zinc finger protein 5
Search

ZFAND5

0.95	Zinc finger A20 domain-containing protein 2

0.56	GO:0010761	fibroblast migration
0.56	GO:0003016	respiratory system process
0.55	GO:0048745	smooth muscle tissue development
0.55	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.54	GO:0060324	face development
0.53	GO:0048705	skeletal system morphogenesis
0.51	GO:0001944	vasculature development
0.50	GO:0001701	in utero embryonic development
0.39	GO:0071356	cellular response to tumor necrosis factor
0.39	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling

0.63	GO:0008270	zinc ion binding
0.54	GO:0003677	DNA binding
0.39	GO:0031593	polyubiquitin modification-dependent protein binding

0.33

GO:0005622

intracellular

sp|O88879|APAF_MOUSE
Apoptotic protease-activating factor 1
Search

APAF1

0.94	Apoptotic peptidase activating factor 1

0.76	GO:0097190	apoptotic signaling pathway
0.73	GO:0042981	regulation of apoptotic process
0.63	GO:1903624	regulation of DNA catabolic process
0.61	GO:0051402	neuron apoptotic process
0.61	GO:2001056	positive regulation of cysteine-type endopeptidase activity
0.60	GO:0001843	neural tube closure
0.58	GO:0030900	forebrain development
0.57	GO:0043068	positive regulation of programmed cell death
0.57	GO:0034976	response to endoplasmic reticulum stress
0.55	GO:0009967	positive regulation of signal transduction

0.74	GO:0043531	ADP binding
0.64	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.54	GO:0042802	identical protein binding
0.52	GO:0008233	peptidase activity
0.51	GO:0005524	ATP binding
0.39	GO:0031072	heat shock protein binding

0.85	GO:0043293	apoptosome
0.47	GO:0005634	nucleus
0.37	GO:0070062	extracellular exosome
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0034774	secretory granule lumen

0.52

GO:0008233

sp|O88888|APBA3_MOUSE
Amyloid beta A4 precursor protein-binding family A member 3
Search

APBA3

0.94	Amyloid beta precursor protein binding family A member 3

0.68	GO:0043086	negative regulation of catalytic activity
0.56	GO:0007268	chemical synaptic transmission
0.53	GO:0001701	in utero embryonic development
0.43	GO:0060255	regulation of macromolecule metabolic process
0.37	GO:0008104	protein localization
0.36	GO:0042886	amide transport
0.36	GO:0006461	protein complex assembly
0.36	GO:0071702	organic substance transport
0.34	GO:0035264	multicellular organism growth
0.34	GO:0007626	locomotory behavior

0.84	GO:0001540	amyloid-beta binding
0.70	GO:0004857	enzyme inhibitor activity
0.50	GO:0019899	enzyme binding

0.53	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0008021	synaptic vesicle

sp|O88890|SH21A_MOUSE
SH2 domain-containing protein 1A
Search

SH2D1A

0.97	SH2 domain containing 1A duplicate b

0.85	GO:0006968	cellular defense response
0.78	GO:0002250	adaptive immune response
0.75	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity
0.75	GO:0007267	cell-cell signaling
0.74	GO:0045087	innate immune response
0.73	GO:0009967	positive regulation of signal transduction
0.69	GO:0006959	humoral immune response

0.82

GO:0005070

SH3/SH2 adaptor activity

0.49

GO:0005737

cytoplasm

sp|O88892|SERF1_MOUSE
Small EDRK-rich factor 1
Search

0.97	Small EDRK-rich factor 1

0.45	GO:0000413	protein peptidyl-prolyl isomerization
0.42	GO:0007399	nervous system development

0.45

GO:0003755

peptidyl-prolyl cis-trans isomerase activity

0.51	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.30	GO:0044425	membrane part

0.45

EC:5.2.1.8

GO:0003755

sp|O88895|HDAC3_MOUSE
Histone deacetylase 3
Search

HDAC3

0.51	Histone deacetylase

0.80	GO:0016575	histone deacetylation
0.60	GO:1903507	negative regulation of nucleic acid-templated transcription
0.58	GO:0071498	cellular response to fluid shear stress
0.57	GO:0042993	positive regulation of transcription factor import into nucleus
0.57	GO:0046329	negative regulation of JNK cascade
0.54	GO:0051225	spindle assembly
0.54	GO:0032008	positive regulation of TOR signaling
0.53	GO:0031647	regulation of protein stability
0.53	GO:0006351	transcription, DNA-templated
0.52	GO:0001934	positive regulation of protein phosphorylation

0.81	GO:0004407	histone deacetylase activity
0.70	GO:0034979	NAD-dependent protein deacetylase activity
0.67	GO:0003714	transcription corepressor activity
0.57	GO:0051059	NF-kappaB binding
0.56	GO:0042826	histone deacetylase binding
0.54	GO:0030332	cyclin binding
0.53	GO:0003682	chromatin binding
0.52	GO:0046872	metal ion binding
0.35	GO:0070491	repressing transcription factor binding
0.34	GO:0051020	GTPase binding

0.56	GO:0005634	nucleus
0.55	GO:0017053	transcriptional repressor complex
0.54	GO:0005876	spindle microtubule
0.49	GO:0005794	Golgi apparatus
0.48	GO:0005829	cytosol
0.48	GO:0070013	intracellular organelle lumen
0.42	GO:0005886	plasma membrane
0.35	GO:1902494	catalytic complex
0.34	GO:0000785	chromatin
0.30	GO:0016021	integral component of membrane

0.81

GO:0004407

sp|O88898|P63_MOUSE
Tumor protein 63
Search

TP63

0.97	Tumor protein 63 isoform A

0.80	GO:0051262	protein tetramerization
0.78	GO:0006915	apoptotic process
0.68	GO:0032502	developmental process
0.60	GO:0010481	epidermal cell division
0.59	GO:1904674	positive regulation of somatic stem cell population maintenance
0.58	GO:0010482	regulation of epidermal cell division
0.58	GO:0045617	negative regulation of keratinocyte differentiation
0.58	GO:0010838	positive regulation of keratinocyte proliferation
0.58	GO:2000381	negative regulation of mesoderm development
0.58	GO:2000271	positive regulation of fibroblast apoptotic process

0.76	GO:0044212	transcription regulatory region DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0097371	MDM2/MDM4 family protein binding
0.56	GO:0002039	p53 binding
0.56	GO:0050699	WW domain binding
0.52	GO:0003682	chromatin binding
0.50	GO:0003684	damaged DNA binding
0.50	GO:0000989	transcription factor activity, transcription factor binding
0.50	GO:0042802	identical protein binding
0.47	GO:0043565	sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.50	GO:0000785	chromatin
0.49	GO:0005794	Golgi apparatus
0.49	GO:0005829	cytosol
0.47	GO:0070013	intracellular organelle lumen
0.47	GO:0030425	dendrite
0.44	GO:0005667	transcription factor complex
0.39	GO:0005791	rough endoplasmic reticulum
0.33	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

sp|O88904|HIPK1_MOUSE
Homeodomain-interacting protein kinase 1
Search

HIPK1

0.88	Homeodomain-interacting protein kinase 1

0.70	GO:0060235	lens induction in camera-type eye
0.69	GO:0061072	iris morphogenesis
0.68	GO:0060059	embryonic retina morphogenesis in camera-type eye
0.68	GO:0072577	endothelial cell apoptotic process
0.67	GO:0010842	retina layer formation
0.67	GO:0048596	embryonic camera-type eye morphogenesis
0.67	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.65	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway
0.64	GO:0007224	smoothened signaling pathway
0.64	GO:0097191	extrinsic apoptotic signaling pathway

0.63	GO:0004672	protein kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.46	GO:0003677	DNA binding
0.46	GO:0046790	virion binding
0.44	GO:0001105	RNA polymerase II transcription coactivator activity
0.44	GO:0001102	RNA polymerase II activating transcription factor binding
0.44	GO:0003714	transcription corepressor activity

0.65	GO:0016605	PML body
0.60	GO:0016607	nuclear speck
0.59	GO:0005813	centrosome
0.53	GO:0005829	cytosol
0.42	GO:0090575	RNA polymerase II transcription factor complex
0.32	GO:0005840	ribosome

sp|O88907|PIAS1_MOUSE
E3 SUMO-protein ligase PIAS1
Search

PIAS1

0.96	Protein inhibitor of activated STAT 1 (Predicted)

0.64	GO:0033235	positive regulation of protein sumoylation
0.61	GO:0045444	fat cell differentiation
0.61	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.59	GO:0016925	protein sumoylation
0.57	GO:0000122	negative regulation of transcription by RNA polymerase II
0.56	GO:0042127	regulation of cell proliferation
0.42	GO:0051152	positive regulation of smooth muscle cell differentiation
0.41	GO:0008542	visual learning
0.41	GO:0000082	G1/S transition of mitotic cell cycle
0.40	GO:0007283	spermatogenesis

0.65	GO:0061665	SUMO ligase activity
0.63	GO:0008270	zinc ion binding
0.58	GO:0031625	ubiquitin protein ligase binding
0.54	GO:0008134	transcription factor binding
0.41	GO:0008022	protein C-terminus binding
0.39	GO:0019904	protein domain specific binding

0.61	GO:0016605	PML body
0.30	GO:0016020	membrane

sp|O88908|SOAT2_MOUSE
Sterol O-acyltransferase 2
Search

SOAT2

0.62	O-acyltransferase

0.77	GO:0034435	cholesterol esterification
0.70	GO:0042632	cholesterol homeostasis
0.65	GO:0034379	very-low-density lipoprotein particle assembly
0.63	GO:0033344	cholesterol efflux
0.62	GO:0008203	cholesterol metabolic process
0.52	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process
0.52	GO:0010878	cholesterol storage
0.52	GO:0010742	macrophage derived foam cell differentiation
0.37	GO:0034383	low-density lipoprotein particle clearance
0.36	GO:0030299	intestinal cholesterol absorption

0.78	GO:0034736	cholesterol O-acyltransferase activity
0.60	GO:0015485	cholesterol binding
0.59	GO:0000062	fatty-acyl-CoA binding
0.33	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.68	GO:0005789	endoplasmic reticulum membrane
0.54	GO:0005903	brush border
0.30	GO:0016021	integral component of membrane

0.78	EC:2.3.1.26	GO:0034736
0.78	KEGG:R01461	GO:0034736

sp|O88909|S22A8_MOUSE
Solute carrier family 22 member 8
Search

SLC22A8

0.86	Solute carrier family 22 (organic anion transporter), member 6, like

0.57	GO:0043252	sodium-independent organic anion transport
0.55	GO:0055085	transmembrane transport
0.53	GO:0015698	inorganic anion transport
0.44	GO:0097254	renal tubular secretion
0.44	GO:0015742	alpha-ketoglutarate transport
0.42	GO:0015747	urate transport
0.40	GO:0009636	response to toxic substance
0.39	GO:0031427	response to methotrexate
0.36	GO:0034635	glutathione transport
0.36	GO:0015697	quaternary ammonium group transport

0.62	GO:0005452	inorganic anion exchanger activity
0.57	GO:0015347	sodium-independent organic anion transmembrane transporter activity
0.42	GO:0015143	urate transmembrane transporter activity
0.38	GO:0015301	anion:anion antiporter activity
0.36	GO:0015651	quaternary ammonium group transmembrane transporter activity
0.36	GO:0005080	protein kinase C binding
0.35	GO:0031404	chloride ion binding
0.35	GO:0016907	G-protein coupled acetylcholine receptor activity
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0004955	prostaglandin receptor activity

0.59	GO:0016323	basolateral plasma membrane
0.48	GO:0005887	integral component of plasma membrane
0.39	GO:0070062	extracellular exosome
0.35	GO:0005901	caveola
0.34	GO:0045211	postsynaptic membrane
0.34	GO:0030054	cell junction
0.33	GO:0043234	protein complex

sp|O88910|MPP3_MOUSE
MAGUK p55 subfamily member 3
Search

MPP3

0.93	Membrane palmitoylated protein 3

0.53	GO:0035335	peptidyl-tyrosine dephosphorylation
0.49	GO:0046710	GDP metabolic process
0.48	GO:0046037	GMP metabolic process
0.42	GO:0007165	signal transduction
0.41	GO:0016310	phosphorylation

0.67	GO:0030165	PDZ domain binding
0.55	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.53	GO:0004725	protein tyrosine phosphatase activity
0.49	GO:0004385	guanylate kinase activity

0.44

GO:0005887

integral component of plasma membrane

0.55

EC:3.1.3

GO:0008138

sp|O88932|KCJ15_MOUSE
ATP-sensitive inward rectifier potassium channel 15
Search

KCNJ15

0.97	ATP-sensitive inward rectifier potassium channel 15

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.50	GO:0051933	amino acid neurotransmitter reuptake
0.49	GO:0060075	regulation of resting membrane potential
0.49	GO:0098712	L-glutamate import across plasma membrane
0.48	GO:0022010	central nervous system myelination
0.48	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.48	GO:0007628	adult walking behavior
0.47	GO:0055075	potassium ion homeostasis

0.84	GO:0005242	inward rectifier potassium channel activity
0.35	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0016323	basolateral plasma membrane
0.45	GO:0098793	presynapse
0.44	GO:0005887	integral component of plasma membrane

tr|O88933|O88933_MOUSE
Extraembryonic, spermatogenesis, homeobox 1
Search

ESX1

0.97	Extraembryonic, spermatogenesis, homeobox 1

0.65	GO:0007275	multicellular organism development
0.61	GO:0006366	transcription by RNA polymerase II
0.60	GO:0007601	visual perception
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0009653	anatomical structure morphogenesis
0.48	GO:0060322	head development
0.48	GO:0003006	developmental process involved in reproduction
0.46	GO:0051254	positive regulation of RNA metabolic process

0.64	GO:0043565	sequence-specific DNA binding
0.53	GO:0003700	DNA binding transcription factor activity
0.49	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0003690	double-stranded DNA binding
0.43	GO:0071837	HMG box domain binding
0.42	GO:0008190	eukaryotic initiation factor 4E binding
0.42	GO:0008301	DNA binding, bending
0.42	GO:0070491	repressing transcription factor binding
0.40	GO:0003682	chromatin binding
0.40	GO:0042803	protein homodimerization activity

0.61	GO:0005634	nucleus
0.39	GO:0032993	protein-DNA complex
0.35	GO:0005737	cytoplasm
0.32	GO:1990904	ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.33

GO:0004222

sp|O88935|SYN1_MOUSE
Synapsin-1
Search

SYN1

0.79	Synapsin IIb

0.82	GO:0099643	signal release from synapse
0.82	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.76	GO:0006836	neurotransmitter transport
0.72	GO:0001505	regulation of neurotransmitter levels
0.69	GO:0051649	establishment of localization in cell
0.51	GO:0097479	synaptic vesicle localization
0.35	GO:0099177	regulation of trans-synaptic signaling
0.34	GO:0051588	regulation of neurotransmitter transport
0.34	GO:1902803	regulation of synaptic vesicle transport
0.34	GO:0098693	regulation of synaptic vesicle cycle

0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0032555	purine ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0019901	protein kinase binding
0.38	GO:0048306	calcium-dependent protein binding
0.37	GO:0003779	actin binding
0.34	GO:0046872	metal ion binding
0.32	GO:0046983	protein dimerization activity
0.32	GO:0005215	transporter activity

0.82	GO:0008021	synaptic vesicle
0.57	GO:0099501	exocytic vesicle membrane
0.55	GO:0014069	postsynaptic density
0.55	GO:0043209	myelin sheath
0.52	GO:0000795	synaptonemal complex
0.51	GO:0048786	presynaptic active zone
0.50	GO:0030424	axon
0.47	GO:0005856	cytoskeleton
0.44	GO:0031201	SNARE complex
0.38	GO:0043679	axon terminus

sp|O88939|ZBT7A_MOUSE
Zinc finger and BTB domain-containing protein 7A
Search

ZBTB7A

0.95	Zinc finger and BTB domain-containing protein 7A

0.53	GO:0000122	negative regulation of transcription by RNA polymerase II
0.47	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding
0.47	GO:0045600	positive regulation of fat cell differentiation
0.45	GO:0008285	negative regulation of cell proliferation
0.43	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0030154	cell differentiation
0.39	GO:0007275	multicellular organism development
0.37	GO:0045670	regulation of osteoclast differentiation
0.37	GO:0061448	connective tissue development
0.37	GO:0006351	transcription, DNA-templated

0.58	GO:0035035	histone acetyltransferase binding
0.56	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0046872	metal ion binding

0.42

GO:0005634

nucleus

sp|O88940|MUSC_MOUSE
Musculin
Search

MSC

0.96	Activated B-cell factor 1

0.69	GO:0014707	branchiomeric skeletal muscle development
0.67	GO:0060539	diaphragm development
0.64	GO:0060021	palate development
0.60	GO:0000122	negative regulation of transcription by RNA polymerase II
0.57	GO:0072277	metanephric glomerular capillary formation
0.57	GO:0060435	bronchiole development
0.57	GO:0072162	metanephric mesenchymal cell differentiation
0.57	GO:0060426	lung vasculature development
0.56	GO:0060766	negative regulation of androgen receptor signaling pathway
0.55	GO:0048286	lung alveolus development

0.68	GO:0046983	protein dimerization activity
0.63	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.59	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.55	GO:0001158	enhancer sequence-specific DNA binding
0.55	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.54	GO:0043425	bHLH transcription factor binding
0.54	GO:0050681	androgen receptor binding
0.52	GO:0042826	histone deacetylase binding
0.52	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0000987	proximal promoter sequence-specific DNA binding

0.50	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part

sp|O88942|NFAC1_MOUSE
Nuclear factor of activated T-cells, cytoplasmic 1
Search

NFATC1

0.97	Nuclear factor of activated T cells c

0.58	GO:0033173	calcineurin-NFAT signaling cascade
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0051254	positive regulation of RNA metabolic process
0.51	GO:0010557	positive regulation of macromolecule biosynthetic process
0.51	GO:0031328	positive regulation of cellular biosynthetic process
0.41	GO:0006366	transcription by RNA polymerase II
0.41	GO:0060854	branching involved in lymph vessel morphogenesis
0.41	GO:0009612	response to mechanical stimulus

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.42	GO:0001067	regulatory region nucleic acid binding
0.42	GO:0001225	RNA polymerase II transcription coactivator binding
0.42	GO:0048273	mitogen-activated protein kinase p38 binding
0.40	GO:0001085	RNA polymerase II transcription factor binding
0.38	GO:0003682	chromatin binding
0.35	GO:0005528	FK506 binding

0.52	GO:0016604	nuclear body
0.51	GO:0000790	nuclear chromatin
0.37	GO:0005667	transcription factor complex
0.37	GO:0005829	cytosol

sp|O88947|FA10_MOUSE
Coagulation factor X
Search

F10

0.88	Coagulation factor IX

0.75	GO:0007596	blood coagulation
0.61	GO:0051897	positive regulation of protein kinase B signaling
0.60	GO:0006508	proteolysis
0.41	GO:0051604	protein maturation
0.37	GO:0017187	peptidyl-glutamic acid carboxylation
0.37	GO:0072376	protein activation cascade
0.36	GO:0006888	ER to Golgi vesicle-mediated transport
0.36	GO:0030335	positive regulation of cell migration
0.35	GO:0010952	positive regulation of peptidase activity
0.34	GO:0006518	peptide metabolic process

0.68	GO:0004252	serine-type endopeptidase activity
0.66	GO:0005509	calcium ion binding
0.55	GO:0005543	phospholipid binding
0.35	GO:0016504	peptidase activator activity
0.34	GO:0005515	protein binding
0.34	GO:0090729	toxin activity

0.63	GO:0005576	extracellular region
0.38	GO:0005796	Golgi lumen
0.37	GO:0005788	endoplasmic reticulum lumen
0.36	GO:0031233	intrinsic component of external side of plasma membrane
0.33	GO:0031982	vesicle
0.30	GO:0016021	integral component of membrane

0.68

GO:0004252

sp|O88951|LIN7B_MOUSE
Protein lin-7 homolog B
Search

LIN7B

0.92	Lin-7 homolog B, crumbs cell polarity complex component

0.76	GO:0099643	signal release from synapse
0.76	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.71	GO:0006887	exocytosis
0.70	GO:0006836	neurotransmitter transport
0.67	GO:0001505	regulation of neurotransmitter levels
0.64	GO:0051649	establishment of localization in cell
0.60	GO:0008104	protein localization
0.60	GO:0042886	amide transport
0.57	GO:0071702	organic substance transport
0.56	GO:0045199	maintenance of epithelial cell apical/basal polarity

0.83	GO:0097016	L27 domain binding
0.45	GO:0008092	cytoskeletal protein binding
0.40	GO:0030165	PDZ domain binding
0.36	GO:0030619	U1 snRNA binding

0.82	GO:0097025	MPP7-DLG1-LIN7 complex
0.76	GO:0016323	basolateral plasma membrane
0.73	GO:0098793	presynapse
0.53	GO:0005911	cell-cell junction
0.42	GO:0014069	postsynaptic density
0.41	GO:0045211	postsynaptic membrane
0.41	GO:0043005	neuron projection
0.37	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.34	GO:0019013	viral nucleocapsid

sp|O88952|LIN7C_MOUSE
Protein lin-7 homolog C
Search

LIN7C

0.96	Lin-7 homolog C, crumbs cell polarity complex component

0.79	GO:0099643	signal release from synapse
0.79	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.74	GO:0006887	exocytosis
0.73	GO:0006836	neurotransmitter transport
0.70	GO:0001505	regulation of neurotransmitter levels
0.66	GO:0051649	establishment of localization in cell
0.63	GO:0015031	protein transport
0.58	GO:0002011	morphogenesis of an epithelial sheet
0.55	GO:0045199	maintenance of epithelial cell apical/basal polarity
0.52	GO:1903361	protein localization to basolateral plasma membrane

0.85	GO:0097016	L27 domain binding
0.51	GO:0008092	cytoskeletal protein binding
0.39	GO:0030165	PDZ domain binding
0.33	GO:0016757	transferase activity, transferring glycosyl groups

0.85	GO:0097025	MPP7-DLG1-LIN7 complex
0.79	GO:0016323	basolateral plasma membrane
0.76	GO:0098793	presynapse
0.55	GO:0005911	cell-cell junction
0.42	GO:0045211	postsynaptic membrane
0.41	GO:0014069	postsynaptic density
0.40	GO:0043005	neuron projection
0.40	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.33

GO:0016757

sp|O88958|GNPI1_MOUSE
Glucosamine-6-phosphate isomerase 1
Search

GNPDA1

0.73	Glucosamine-6-phosphate isomerase

0.78	GO:0006044	N-acetylglucosamine metabolic process
0.60	GO:0005975	carbohydrate metabolic process
0.59	GO:0006043	glucosamine catabolic process
0.43	GO:0006091	generation of precursor metabolites and energy
0.36	GO:0007338	single fertilization
0.34	GO:0006002	fructose 6-phosphate metabolic process
0.33	GO:0044283	small molecule biosynthetic process
0.32	GO:1901576	organic substance biosynthetic process

0.80	GO:0004342	glucosamine-6-phosphate deaminase activity
0.34	GO:0005515	protein binding

0.49	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus

0.80	EC:3.5.99.6	GO:0004342
0.80	KEGG:R00765	GO:0004342

sp|O88962|CP8B1_MOUSE
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
Search

CYP8B1

0.97	7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase

0.53	GO:0055114	oxidation-reduction process
0.48	GO:0046457	prostanoid biosynthetic process
0.48	GO:0006693	prostaglandin metabolic process
0.44	GO:0006699	bile acid biosynthetic process
0.41	GO:0035754	B cell chemotaxis
0.41	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway
0.41	GO:0060740	prostate gland epithelium morphogenesis
0.40	GO:0050679	positive regulation of epithelial cell proliferation
0.38	GO:0016125	sterol metabolic process
0.37	GO:0006706	steroid catabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.68	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.50	GO:0008116	prostaglandin-I synthase activity
0.35	GO:0019825	oxygen binding
0.31	GO:0008168	methyltransferase activity

0.67	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0031090	organelle membrane
0.35	GO:0005901	caveola
0.33	GO:0005634	nucleus
0.33	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.68	EC:1.14	GO:0016705
0.50	KEGG:R02267	GO:0008116

sp|O88967|YMEL1_MOUSE
ATP-dependent zinc metalloprotease YME1L1
Search

YME1L1

0.96	ATP-dependent zinc metalloprotease YME1L1

0.61	GO:0006508	proteolysis
0.51	GO:0035694	mitochondrial protein catabolic process
0.50	GO:0034214	protein hexamerization
0.47	GO:0008283	cell proliferation
0.46	GO:0043066	negative regulation of apoptotic process
0.44	GO:0051604	protein maturation
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0009059	macromolecule biosynthetic process

0.70	GO:0004222	metalloendopeptidase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0004176	ATP-dependent peptidase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0000062	fatty-acyl-CoA binding
0.32	GO:0003735	structural constituent of ribosome

0.46	GO:0016604	nuclear body
0.42	GO:0031966	mitochondrial membrane
0.42	GO:0019866	organelle inner membrane
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.70

GO:0004222

sp|O88968|TCO2_MOUSE
Transcobalamin-2
Search

TCN2

0.97	Transcobalamin II

0.78	GO:0015889	cobalamin transport
0.44	GO:0006824	cobalt ion transport
0.35	GO:0009235	cobalamin metabolic process

0.75	GO:0031419	cobalamin binding
0.37	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.57	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.38	GO:0043202	lysosomal lumen
0.36	GO:0005768	endosome
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

sp|O88974|SETB1_MOUSE
Histone-lysine N-methyltransferase SETDB1
Search

SETDB1

0.48	Histone-lysine N-methyltransferase

0.77	GO:0034968	histone lysine methylation
0.68	GO:0090309	positive regulation of methylation-dependent chromatin silencing
0.62	GO:0007265	Ras protein signal transduction
0.44	GO:0033273	response to vitamin
0.44	GO:0045471	response to ethanol
0.43	GO:0001833	inner cell mass cell proliferation
0.43	GO:0061647	histone H3-K9 modification
0.42	GO:0018023	peptidyl-lysine trimethylation
0.42	GO:0060348	bone development
0.40	GO:0000122	negative regulation of transcription by RNA polymerase II

0.78	GO:0018024	histone-lysine N-methyltransferase activity
0.65	GO:1990841	promoter-specific chromatin binding
0.62	GO:0008270	zinc ion binding
0.54	GO:0003677	DNA binding
0.36	GO:0005515	protein binding
0.31	GO:0003700	DNA binding transcription factor activity

0.64	GO:0005694	chromosome
0.60	GO:0005634	nucleus
0.53	GO:0005829	cytosol
0.53	GO:0031974	membrane-enclosed lumen
0.47	GO:0044446	intracellular organelle part
0.46	GO:0005886	plasma membrane
0.32	GO:0005667	transcription factor complex
0.30	GO:0031224	intrinsic component of membrane

0.78

GO:0018024

sp|O88978|TILB_MOUSE
Protein tilB homolog
Search

LRRC6

0.97	Leucine-rich repeat-containing protein 6

0.86	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry
0.85	GO:0036158	outer dynein arm assembly
0.85	GO:0036159	inner dynein arm assembly
0.85	GO:0044458	motile cilium assembly
0.84	GO:0030317	flagellated sperm motility
0.83	GO:0008584	male gonad development

0.36	GO:0005515	protein binding
0.34	GO:0030246	carbohydrate binding

0.76	GO:0005929	cilium
0.49	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|O88983|STX8_MOUSE
Syntaxin-8
Search

STX8

0.93	Putative syntaxin-8 protein kinase regulator

0.66	GO:0045022	early endosome to late endosome transport
0.64	GO:1903076	regulation of protein localization to plasma membrane
0.64	GO:0071346	cellular response to interferon-gamma
0.53	GO:0006906	vesicle fusion
0.52	GO:0065009	regulation of molecular function
0.52	GO:0048278	vesicle docking
0.47	GO:0006886	intracellular protein transport
0.42	GO:0008333	endosome to lysosome transport
0.34	GO:0016310	phosphorylation

0.68	GO:0019869	chloride channel inhibitor activity
0.66	GO:0000149	SNARE binding
0.60	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0005484	SNAP receptor activity
0.34	GO:0016301	kinase activity

0.62	GO:0045335	phagocytic vesicle
0.62	GO:0055037	recycling endosome
0.61	GO:0005770	late endosome
0.61	GO:0005769	early endosome
0.60	GO:0005802	trans-Golgi network
0.60	GO:0048471	perinuclear region of cytoplasm
0.54	GO:0005829	cytosol
0.53	GO:0031201	SNARE complex
0.41	GO:0005765	lysosomal membrane
0.40	GO:0010008	endosome membrane

sp|O88986|KBL_MOUSE
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Search

GCAT

0.49	Glycine C-acetyltransferase

0.79	GO:0006567	threonine catabolic process
0.49	GO:0009058	biosynthetic process
0.37	GO:0006544	glycine metabolic process
0.36	GO:0042737	drug catabolic process
0.36	GO:0006334	nucleosome assembly
0.35	GO:0007313	maternal specification of dorsal/ventral axis, oocyte, soma encoded
0.35	GO:0007362	terminal region determination
0.35	GO:0008293	torso signaling pathway
0.34	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.33	GO:0016485	protein processing

0.83	GO:0008890	glycine C-acetyltransferase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.49	GO:0016874	ligase activity
0.33	GO:0003677	DNA binding
0.33	GO:0005509	calcium ion binding

0.51	GO:0016607	nuclear speck
0.44	GO:0005739	mitochondrion
0.44	GO:0019866	organelle inner membrane
0.35	GO:0000786	nucleosome

0.83	EC:2.3.1.29	GO:0008890
0.83	KEGG:R00371	GO:0008890

sp|O88987|AKAP3_MOUSE
A-kinase anchor protein 3
Search

AKAP3

0.97	A-kinase anchoring protein 3

0.68	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.61	GO:0010738	regulation of protein kinase A signaling
0.57	GO:0008104	protein localization
0.48	GO:0016310	phosphorylation
0.42	GO:0030317	flagellated sperm motility
0.42	GO:0044458	motile cilium assembly
0.39	GO:0007340	acrosome reaction
0.35	GO:0051234	establishment of localization

0.74	GO:0051018	protein kinase A binding
0.49	GO:0016301	kinase activity
0.36	GO:0003924	GTPase activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0035686	sperm fibrous sheath
0.77	GO:0097228	sperm principal piece
0.71	GO:0001669	acrosomal vesicle
0.41	GO:0030018	Z disc
0.40	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005634	nucleus
0.32	GO:0005952	cAMP-dependent protein kinase complex
0.32	GO:0005856	cytoskeleton

sp|O88990|ACTN3_MOUSE
Alpha-actinin-3
Search

ACTN3

0.94	Truncated alpha-actinin

0.59	GO:0006936	muscle contraction
0.56	GO:1904025	positive regulation of glucose catabolic process to lactate via pyruvate
0.56	GO:0048513	animal organ development
0.55	GO:0014862	regulation of skeletal muscle contraction by chemo-mechanical energy conversion
0.55	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway
0.55	GO:1900159	positive regulation of bone mineralization involved in bone maturation
0.55	GO:0048633	positive regulation of skeletal muscle tissue growth
0.55	GO:0031446	regulation of fast-twitch skeletal muscle fiber contraction
0.55	GO:0045214	sarcomere organization
0.55	GO:0090324	negative regulation of oxidative phosphorylation

0.73	GO:0003779	actin binding
0.69	GO:0005509	calcium ion binding
0.55	GO:0070080	titin Z domain binding
0.55	GO:0032403	protein complex binding
0.54	GO:0030375	thyroid hormone receptor coactivator activity
0.54	GO:0051373	FATZ binding
0.54	GO:0031432	titin binding
0.53	GO:0030274	LIM domain binding
0.53	GO:0044325	ion channel binding
0.51	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding

0.60	GO:0030018	Z disc
0.51	GO:0030175	filopodium
0.51	GO:0005903	brush border
0.51	GO:0005925	focal adhesion
0.40	GO:0005886	plasma membrane
0.38	GO:0015629	actin cytoskeleton
0.38	GO:0070062	extracellular exosome
0.38	GO:0044430	cytoskeletal part
0.37	GO:0030863	cortical cytoskeleton
0.37	GO:0031143	pseudopodium

sp|O88992|C1QRF_MOUSE
C1q-related factor
Search

0.93	Phospholipase C delta 3

0.52	GO:0061743	motor learning
0.52	GO:0099558	maintenance of synapse structure
0.51	GO:0016322	neuron remodeling
0.44	GO:0050807	regulation of synapse organization
0.41	GO:0051259	protein oligomerization
0.32	GO:0007626	locomotory behavior

0.47

GO:0005515

protein binding

0.73	GO:0005581	collagen trimer
0.63	GO:0005576	extracellular region
0.53	GO:0044301	climbing fiber
0.47	GO:0098793	presynapse
0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|O88995|IKBL1_MOUSE
NF-kappa-B inhibitor-like protein 1
Search

NFKBIL1

0.97	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1

0.86	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway
0.85	GO:0034122	negative regulation of toll-like receptor signaling pathway
0.85	GO:0032720	negative regulation of tumor necrosis factor production
0.84	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.83	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.82	GO:0071222	cellular response to lipopolysaccharide
0.41	GO:0042994	cytoplasmic sequestering of transcription factor
0.40	GO:0006915	apoptotic process
0.39	GO:0010469	regulation of receptor activity
0.39	GO:0006955	immune response

0.41	GO:0005164	tumor necrosis factor receptor binding
0.40	GO:0005125	cytokine activity
0.38	GO:0004674	protein serine/threonine kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.66	GO:0005829	cytosol
0.60	GO:0005634	nucleus
0.39	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.38

GO:0004674

sp|O88998|NOE1_MOUSE
Noelin
Search

OLFM1

0.97	Olfactomedin 1

0.74	GO:0007399	nervous system development
0.51	GO:0003190	atrioventricular valve formation
0.50	GO:0060317	cardiac epithelial to mesenchymal transition
0.49	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.44	GO:0010628	positive regulation of gene expression
0.43	GO:0010629	negative regulation of gene expression
0.40	GO:0023041	neuronal signal transduction
0.39	GO:0061387	regulation of extent of cell growth
0.38	GO:0010769	regulation of cell morphogenesis involved in differentiation
0.38	GO:0048638	regulation of developmental growth

0.37	GO:0001540	amyloid-beta binding
0.34	GO:0005515	protein binding

0.39	GO:0044295	axonal growth cone
0.39	GO:0043204	perikaryon
0.37	GO:0045202	synapse
0.37	GO:0030054	cell junction
0.37	GO:0005615	extracellular space
0.37	GO:0032281	AMPA glutamate receptor complex
0.37	GO:0005783	endoplasmic reticulum
0.36	GO:0098590	plasma membrane region

sp|O89001|CBPD_MOUSE
Carboxypeptidase D
Search

0.71	Carboxypeptidase D

0.61	GO:0006508	proteolysis
0.43	GO:0071352	cellular response to interleukin-2
0.41	GO:0051604	protein maturation
0.38	GO:0006518	peptide metabolic process

0.78	GO:0004181	metallocarboxypeptidase activity
0.73	GO:0004185	serine-type carboxypeptidase activity
0.63	GO:0008270	zinc ion binding
0.42	GO:0051721	protein phosphatase 2A binding
0.40	GO:0032403	protein complex binding

0.42	GO:0005615	extracellular space
0.41	GO:1903561	extracellular vesicle
0.41	GO:0005802	trans-Golgi network
0.41	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005886	plasma membrane
0.37	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.78

EC:3.4.17

GO:0004181

tr|O89006|O89006_MOUSE
Magea1 protein
Search

0.90	Melanoma-associated antigen 9

0.40

GO:0005515

protein binding

0.56	GO:0005654	nucleoplasm
0.55	GO:0005829	cytosol

tr|O89009|O89009_MOUSE
MCG115462
Search

MAGEA10

0.89	Melanoma-associated antigen 9

0.37

GO:0005515

protein binding

0.54	GO:0005654	nucleoplasm
0.53	GO:0005829	cytosol

tr|O89010|O89010_MOUSE
MCG114343
Search

0.88	Melanoma-associated antigen 8

0.50	GO:0000122	negative regulation of transcription by RNA polymerase II
0.48	GO:0045746	negative regulation of Notch signaling pathway
0.41	GO:0051443	positive regulation of ubiquitin-protein transferase activity
0.39	GO:0033234	negative regulation of protein sumoylation
0.38	GO:0090398	cellular senescence
0.38	GO:0044257	cellular protein catabolic process
0.38	GO:1901984	negative regulation of protein acetylation
0.38	GO:0072331	signal transduction by p53 class mediator
0.36	GO:0006351	transcription, DNA-templated

0.53	GO:0042826	histone deacetylase binding
0.40	GO:0031625	ubiquitin protein ligase binding
0.38	GO:0070491	repressing transcription factor binding

0.51	GO:0005654	nucleoplasm
0.51	GO:0005829	cytosol
0.36	GO:0005730	nucleolus
0.34	GO:0005886	plasma membrane

tr|O89012|O89012_MOUSE
MCG115467
Search

0.88	Melanoma-associated antigen 10

0.54	GO:0005654	nucleoplasm
0.53	GO:0005829	cytosol

sp|O89013|OBRG_MOUSE
Leptin receptor gene-related protein
Search

LEPROT

0.97	Leptin receptor overlapping transcript

0.51	GO:2000009	negative regulation of protein localization to cell surface
0.51	GO:0060400	negative regulation of growth hormone receptor signaling pathway
0.49	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway
0.47	GO:0046426	negative regulation of JAK-STAT cascade
0.38	GO:1903955	positive regulation of protein targeting to mitochondrion
0.33	GO:0005975	carbohydrate metabolic process

0.43	GO:0005102	receptor binding
0.33	GO:0016868	intramolecular transferase activity, phosphotransferases
0.33	GO:0000287	magnesium ion binding

0.46	GO:0005768	endosome
0.40	GO:0044433	cytoplasmic vesicle part
0.40	GO:0000139	Golgi membrane
0.40	GO:0098805	whole membrane
0.30	GO:0016021	integral component of membrane

0.33

EC:5.4.2

GO:0016868

sp|O89016|ABCD4_MOUSE
ATP-binding cassette sub-family D member 4
Search

ABCD4

0.95	ATP-binding cassette sub-family D member 4

0.57	GO:1990823	response to leukemia inhibitory factor
0.55	GO:0055085	transmembrane transport
0.54	GO:0071345	cellular response to cytokine stimulus
0.50	GO:0009235	cobalamin metabolic process

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.53	GO:0042579	microbody
0.51	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0005765	lysosomal membrane
0.33	GO:0043190	ATP-binding cassette (ABC) transporter complex

sp|O89017|LGMN_MOUSE
Legumain
Search

LGMN

0.93

Legumain

0.59	GO:0006508	proteolysis
0.57	GO:1901185	negative regulation of ERBB signaling pathway
0.57	GO:0040015	negative regulation of multicellular organism growth
0.56	GO:0003014	renal system process
0.55	GO:0010447	response to acidic pH
0.55	GO:0043524	negative regulation of neuron apoptotic process
0.54	GO:0032801	receptor catabolic process
0.51	GO:0044257	cellular protein catabolic process
0.45	GO:0031103	axon regeneration
0.44	GO:0042246	tissue regeneration

0.60

GO:0008233

peptidase activity

0.53	GO:0005764	lysosome
0.53	GO:0005770	late endosome
0.53	GO:0045177	apical part of cell
0.36	GO:0070062	extracellular exosome
0.35	GO:0031904	endosome lumen
0.35	GO:0005775	vacuolar lumen

0.60

GO:0008233

sp|O89019|INVS_MOUSE
Inversin
Search

INVS

0.65

Inversin

0.82	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.50	GO:0016055	Wnt signaling pathway
0.48	GO:0007275	multicellular organism development
0.41	GO:0060429	epithelium development

0.51

GO:0005516

calmodulin binding

0.47	GO:0005856	cytoskeleton
0.45	GO:0097543	ciliary inversin compartment
0.44	GO:0097546	ciliary base
0.43	GO:0099512	supramolecular fiber
0.40	GO:0005634	nucleus
0.39	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|O89020|AFAM_MOUSE
Afamin
Search

AFM

0.97	LOW QUALITY PROTEIN: afamin

0.62	GO:0071693	protein transport within extracellular region
0.54	GO:0050821	protein stabilization
0.52	GO:0051180	vitamin transport
0.50	GO:0051659	maintenance of mitochondrion location
0.47	GO:0019836	hemolysis by symbiont of host erythrocytes
0.45	GO:0009267	cellular response to starvation
0.45	GO:0043066	negative regulation of apoptotic process
0.38	GO:0001542	ovulation from ovarian follicle
0.38	GO:0042448	progesterone metabolic process
0.37	GO:0060395	SMAD protein signal transduction

0.61	GO:0008431	vitamin E binding
0.47	GO:0005504	fatty acid binding
0.46	GO:0015643	toxic substance binding
0.45	GO:0019825	oxygen binding
0.42	GO:0051087	chaperone binding
0.42	GO:0042802	identical protein binding
0.41	GO:0030170	pyridoxal phosphate binding
0.38	GO:0003677	DNA binding
0.35	GO:0046872	metal ion binding
0.33	GO:0019899	enzyme binding

0.73	GO:0005615	extracellular space
0.46	GO:1903561	extracellular vesicle
0.44	GO:0043209	myelin sheath
0.41	GO:0005794	Golgi apparatus
0.40	GO:0005783	endoplasmic reticulum
0.39	GO:0043234	protein complex
0.34	GO:0005604	basement membrane
0.32	GO:0005634	nucleus

sp|O89023|TPP1_MOUSE
Tripeptidyl-peptidase 1
Search

TPP1

0.93	Tripeptidyl peptidase I

0.61	GO:0045453	bone resorption
0.61	GO:0006508	proteolysis
0.58	GO:0050885	neuromuscular process controlling balance
0.57	GO:0007040	lysosome organization
0.56	GO:0007399	nervous system development
0.55	GO:0043171	peptide catabolic process
0.55	GO:0030855	epithelial cell differentiation
0.42	GO:0007626	locomotory behavior
0.36	GO:0036498	IRE1-mediated unfolded protein response
0.34	GO:0030163	protein catabolic process

0.69	GO:0004252	serine-type endopeptidase activity
0.63	GO:0008240	tripeptidyl-peptidase activity
0.49	GO:0046872	metal ion binding
0.37	GO:0042277	peptide binding
0.35	GO:0005515	protein binding

0.56	GO:0005764	lysosome
0.45	GO:0005739	mitochondrion
0.45	GO:0042470	melanosome
0.37	GO:0070062	extracellular exosome
0.36	GO:0005775	vacuolar lumen
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004252

sp|O89026|ROBO1_MOUSE
Roundabout homolog 1
Search

ROBO1

0.97	Roundabout guidance receptor 1

0.85	GO:0035385	Roundabout signaling pathway
0.81	GO:0007411	axon guidance
0.80	GO:0007507	heart development
0.57	GO:0021836	chemorepulsion involved in postnatal olfactory bulb interneuron migration
0.57	GO:0050925	negative regulation of negative chemotaxis
0.56	GO:0033600	negative regulation of mammary gland epithelial cell proliferation
0.56	GO:0070100	negative regulation of chemokine-mediated signaling pathway
0.56	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway
0.55	GO:0002042	cell migration involved in sprouting angiogenesis
0.54	GO:0035025	positive regulation of Rho protein signal transduction

0.55	GO:0030275	LRR domain binding
0.48	GO:0042802	identical protein binding
0.38	GO:0008046	axon guidance receptor activity

0.49	GO:0009986	cell surface
0.42	GO:0005886	plasma membrane
0.38	GO:0030424	axon
0.38	GO:0005737	cytoplasm
0.37	GO:0031252	cell leading edge
0.36	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0043025	neuronal cell body
0.30	GO:0016021	integral component of membrane

sp|O89029|MATN4_MOUSE
Matrilin-4
Search

MATN4

0.91	Matrilin 4

0.36	GO:0030198	extracellular matrix organization
0.33	GO:0010466	negative regulation of peptidase activity
0.30	GO:0006950	response to stress

0.69	GO:0005509	calcium ion binding
0.36	GO:0000287	magnesium ion binding
0.34	GO:0005515	protein binding
0.33	GO:0030414	peptidase inhibitor activity

0.35	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|O89032|SPD2A_MOUSE
SH3 and PX domain-containing protein 2A
Search

SH3PXD2A

0.88	SH3 and PX domain-containing protein 2A

0.55	GO:0071800	podosome assembly
0.53	GO:0072675	osteoclast fusion
0.52	GO:0006801	superoxide metabolic process
0.47	GO:0043085	positive regulation of catalytic activity
0.45	GO:0055114	oxidation-reduction process

0.76	GO:0035091	phosphatidylinositol binding
0.62	GO:0016175	superoxide-generating NADPH oxidase activity
0.54	GO:0016176	superoxide-generating NADPH oxidase activator activity
0.30	GO:0005515	protein binding

0.58	GO:0002102	podosome
0.41	GO:0005737	cytoplasm
0.30	GO:0030054	cell junction
0.30	GO:0042995	cell projection

0.62

EC:1.6.3

GO:0016175

sp|O89033|CDC6_MOUSE
Cell division control protein 6 homolog
Search

CDC6

0.70	Cell division control protein 6

0.72	GO:0006270	DNA replication initiation
0.66	GO:0051301	cell division
0.60	GO:0032467	positive regulation of cytokinesis
0.60	GO:0051984	positive regulation of chromosome segregation
0.58	GO:0030071	regulation of mitotic metaphase/anaphase transition
0.55	GO:0000278	mitotic cell cycle
0.45	GO:1904117	cellular response to vasopressin
0.43	GO:1904385	cellular response to angiotensin
0.42	GO:0048146	positive regulation of fibroblast proliferation
0.42	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity

0.57	GO:0019900	kinase binding
0.47	GO:0032559	adenyl ribonucleotide binding
0.46	GO:0008144	drug binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0003779	actin binding
0.38	GO:0003682	chromatin binding
0.32	GO:0004674	protein serine/threonine kinase activity
0.31	GO:0016787	hydrolase activity

0.60	GO:0051233	spindle midzone
0.58	GO:0005634	nucleus
0.57	GO:0000922	spindle pole
0.36	GO:0043233	organelle lumen
0.34	GO:0005829	cytosol
0.32	GO:0000785	chromatin
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0004674

sp|O89050|MKLN1_MOUSE
Muskelin
Search

MKLN1

0.94	Muskelin 1, intracellular mediator containing kelch motifs

0.82	GO:0007160	cell-matrix adhesion
0.77	GO:0031532	actin cytoskeleton reorganization
0.69	GO:0008360	regulation of cell shape
0.36	GO:0007165	signal transduction
0.34	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0010467	gene expression
0.33	GO:0034645	cellular macromolecule biosynthetic process

0.73	GO:0042802	identical protein binding
0.34	GO:0003735	structural constituent of ribosome

0.83	GO:0001726	ruffle
0.76	GO:0005938	cell cortex
0.68	GO:0005829	cytosol
0.34	GO:0005840	ribosome

sp|O89051|ITM2B_MOUSE
Integral membrane protein 2B
Search

ITM2B

0.97	Integral membrane protein 2B

0.63	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process
0.45	GO:0007399	nervous system development
0.39	GO:0006915	apoptotic process
0.39	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.38	GO:0008285	negative regulation of cell proliferation
0.37	GO:0038034	signal transduction in absence of ligand
0.37	GO:0002317	plasma cell differentiation
0.37	GO:0045892	negative regulation of transcription, DNA-templated
0.36	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0002377	immunoglobulin production

0.60	GO:0001540	amyloid-beta binding
0.42	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0008134	transcription factor binding

0.53	GO:0030660	Golgi-associated vesicle membrane
0.53	GO:0031301	integral component of organelle membrane
0.53	GO:0005615	extracellular space
0.52	GO:0005794	Golgi apparatus
0.48	GO:1903561	extracellular vesicle
0.44	GO:0005886	plasma membrane
0.42	GO:0010008	endosome membrane
0.40	GO:0031984	organelle subcompartment
0.39	GO:0035189	Rb-E2F complex

sp|O89053|COR1A_MOUSE
Coronin-1A
Search

CORO1A

0.69

Coronin

0.74	GO:0001845	phagolysosome assembly
0.70	GO:0030595	leukocyte chemotaxis
0.65	GO:0030036	actin cytoskeleton organization
0.61	GO:0061502	early endosome to recycling endosome transport
0.60	GO:0032796	uropod organization
0.60	GO:0030334	regulation of cell migration
0.60	GO:0038180	nerve growth factor signaling pathway
0.59	GO:0043320	natural killer cell degranulation
0.59	GO:0031339	negative regulation of vesicle fusion
0.58	GO:0071353	cellular response to interleukin-4

0.76	GO:0051015	actin filament binding
0.58	GO:0032036	myosin heavy chain binding
0.57	GO:0043548	phosphatidylinositol 3-kinase binding
0.56	GO:0003785	actin monomer binding
0.55	GO:0008022	protein C-terminus binding
0.51	GO:0042803	protein homodimerization activity
0.51	GO:0048365	Rac GTPase binding
0.35	GO:0071933	Arp2/3 complex binding
0.34	GO:0045296	cadherin binding
0.34	GO:0003723	RNA binding

0.65	GO:0015629	actin cytoskeleton
0.62	GO:0030027	lamellipodium
0.57	GO:0001891	phagocytic cup
0.57	GO:0001772	immunological synapse
0.55	GO:0031982	vesicle
0.54	GO:0030424	axon
0.54	GO:0030863	cortical cytoskeleton
0.52	GO:0016600	flotillin complex
0.52	GO:0005911	cell-cell junction
0.51	GO:0016328	lateral plasma membrane

sp|O89079|COPE_MOUSE
Coatomer subunit epsilon
Search

COPE

0.75	Coatomer protein complex subunit epsilon

0.80	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.59	GO:0015031	protein transport
0.47	GO:0006891	intra-Golgi vesicle-mediated transport
0.46	GO:0006888	ER to Golgi vesicle-mediated transport

0.61	GO:0005198	structural molecule activity
0.34	GO:0005515	protein binding

0.66	GO:0000139	Golgi membrane
0.66	GO:0031410	cytoplasmic vesicle
0.48	GO:0005654	nucleoplasm
0.46	GO:0012506	vesicle membrane
0.45	GO:0030117	membrane coat
0.45	GO:0098805	whole membrane
0.34	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005829	cytosol
0.33	GO:0019028	viral capsid
0.30	GO:0031224	intrinsic component of membrane

sp|O89084|PDE4A_MOUSE
cAMP-specific 3',5'-cyclic phosphodiesterase 4A
Search

PDE4A

0.55	Phosphodiesterase

0.61	GO:0007165	signal transduction
0.58	GO:0006198	cAMP catabolic process
0.53	GO:0043949	regulation of cAMP-mediated signaling
0.53	GO:0010738	regulation of protein kinase A signaling
0.51	GO:0035690	cellular response to drug
0.51	GO:0003008	system process
0.49	GO:0032743	positive regulation of interleukin-2 production
0.49	GO:1901898	negative regulation of relaxation of cardiac muscle
0.48	GO:0030593	neutrophil chemotaxis
0.48	GO:0032729	positive regulation of interferon-gamma production

0.79	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.58	GO:0030552	cAMP binding
0.54	GO:0046872	metal ion binding
0.46	GO:0051117	ATPase binding
0.46	GO:0097110	scaffold protein binding
0.46	GO:0044325	ion channel binding
0.38	GO:0043015	gamma-tubulin binding
0.37	GO:0008144	drug binding
0.37	GO:0031698	beta-2 adrenergic receptor binding
0.35	GO:0031625	ubiquitin protein ligase binding

0.50	GO:0005829	cytosol
0.49	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0044428	nuclear part
0.45	GO:0005813	centrosome
0.45	GO:0034704	calcium channel complex
0.44	GO:0070013	intracellular organelle lumen
0.43	GO:0071944	cell periphery
0.42	GO:0012505	endomembrane system
0.39	GO:0060076	excitatory synapse
0.39	GO:0031967	organelle envelope

0.79

GO:0004114

sp|O89086|RBM3_MOUSE
RNA-binding protein 3
Search

RBM3

0.41	Cold-inducible RNA-binding protein isoform B

0.48	GO:0034063	stress granule assembly
0.47	GO:0009409	response to cold
0.46	GO:0030308	negative regulation of cell growth
0.45	GO:1902806	regulation of cell cycle G1/S phase transition
0.45	GO:0017148	negative regulation of translation
0.41	GO:0045727	positive regulation of translation
0.40	GO:0033554	cellular response to stress
0.39	GO:0048255	mRNA stabilization
0.38	GO:0009411	response to UV
0.37	GO:0070918	production of small RNA involved in gene silencing by RNA

0.59	GO:0003723	RNA binding
0.47	GO:0030371	translation repressor activity
0.38	GO:0043023	ribosomal large subunit binding
0.35	GO:0005515	protein binding
0.34	GO:0047750	cholestenol delta-isomerase activity
0.32	GO:0003677	DNA binding

0.52	GO:0005730	nucleolus
0.50	GO:0005654	nucleoplasm
0.46	GO:0010494	cytoplasmic stress granule
0.39	GO:0030425	dendrite
0.36	GO:0015934	large ribosomal subunit
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:5.3.3.5

GO:0047750

sp|O89090|SP1_MOUSE
Transcription factor Sp1
Search

SP1

0.96	Transcription factor Sp1

0.69	GO:0006357	regulation of transcription by RNA polymerase II
0.67	GO:1904828	positive regulation of hydrogen sulfide biosynthetic process
0.64	GO:1905564	positive regulation of vascular endothelial cell proliferation
0.63	GO:0043923	positive regulation by host of viral transcription
0.61	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.60	GO:0045766	positive regulation of angiogenesis
0.55	GO:0006366	transcription by RNA polymerase II
0.54	GO:0045893	positive regulation of transcription, DNA-templated
0.41	GO:0060136	embryonic process involved in female pregnancy
0.40	GO:0043353	enucleate erythrocyte differentiation

0.63	GO:0071837	HMG box domain binding
0.61	GO:0070491	repressing transcription factor binding
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0042826	histone deacetylase binding
0.59	GO:0008022	protein C-terminus binding
0.58	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0042803	protein homodimerization activity
0.42	GO:0043425	bHLH transcription factor binding
0.41	GO:0001046	core promoter sequence-specific DNA binding
0.41	GO:0001085	RNA polymerase II transcription factor binding

0.61	GO:0005634	nucleus
0.58	GO:0017053	transcriptional repressor complex
0.53	GO:0000785	chromatin
0.51	GO:0031974	membrane-enclosed lumen
0.37	GO:0032993	protein-DNA complex
0.34	GO:0005737	cytoplasm

sp|O89091|KLF10_MOUSE
Krueppel-like factor 10
Search

KLF10

0.97	Kruppel like factor 10

0.63	GO:0045672	positive regulation of osteoclast differentiation
0.62	GO:0030282	bone mineralization
0.62	GO:0035019	somatic stem cell population maintenance
0.59	GO:0007623	circadian rhythm
0.57	GO:0009267	cellular response to starvation
0.55	GO:0006366	transcription by RNA polymerase II
0.55	GO:0045944	positive regulation of transcription by RNA polymerase II
0.54	GO:0045892	negative regulation of transcription, DNA-templated
0.40	GO:0042752	regulation of circadian rhythm
0.40	GO:1901653	cellular response to peptide

0.60	GO:0001046	core promoter sequence-specific DNA binding
0.59	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.58	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0005515	protein binding
0.35	GO:0046872	metal ion binding

0.48	GO:0005634	nucleus
0.38	GO:0005925	focal adhesion
0.36	GO:0005829	cytosol
0.36	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part

sp|O89093|CCL20_MOUSE
C-C motif chemokine 20
Search

CCL20

0.76	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.66	GO:0072679	thymocyte migration
0.64	GO:2000403	positive regulation of lymphocyte migration
0.63	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.63	GO:2000404	regulation of T cell migration
0.52	GO:0071674	mononuclear cell migration
0.52	GO:0097530	granulocyte migration
0.51	GO:0071347	cellular response to interleukin-1

0.84	GO:0008009	chemokine activity
0.66	GO:0031731	CCR6 chemokine receptor binding
0.38	GO:0031727	CCR2 chemokine receptor binding
0.38	GO:0031726	CCR1 chemokine receptor binding
0.37	GO:0016004	phospholipase activator activity
0.34	GO:0008201	heparin binding
0.34	GO:0004672	protein kinase activity

0.72	GO:0005615	extracellular space
0.39	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|O89094|CASPE_MOUSE
Caspase-14
Search

CASP14

0.97	Caspase 14, apoptosis-related cysteine peptidase

0.79	GO:0070268	cornification
0.61	GO:0006508	proteolysis
0.56	GO:0097194	execution phase of apoptosis
0.51	GO:0042981	regulation of apoptotic process
0.41	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway
0.41	GO:0050727	regulation of inflammatory response
0.41	GO:0050718	positive regulation of interleukin-1 beta secretion
0.41	GO:0051882	mitochondrial depolarization
0.40	GO:0050717	positive regulation of interleukin-1 alpha secretion
0.40	GO:0071260	cellular response to mechanical stimulus

0.75	GO:0004197	cysteine-type endopeptidase activity
0.41	GO:0050700	CARD domain binding
0.39	GO:0019900	kinase binding
0.38	GO:0042802	identical protein binding
0.34	GO:0097110	scaffold protein binding

0.55	GO:0005829	cytosol
0.50	GO:0005739	mitochondrion
0.50	GO:0005634	nucleus
0.46	GO:0045095	keratin filament
0.42	GO:0097179	protease inhibitor complex
0.41	GO:0031012	extracellular matrix
0.39	GO:0070062	extracellular exosome
0.33	GO:0043005	neuron projection

0.75

GO:0004197

sp|O89098|CYTF_MOUSE
Cystatin-F
Search

CST7

0.74	Cystatin-F

0.76	GO:0010951	negative regulation of endopeptidase activity
0.54	GO:2000116	regulation of cysteine-type endopeptidase activity
0.36	GO:0006955	immune response

0.83	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.55	GO:0002020	protease binding

0.50	GO:0005615	extracellular space
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|O89100|GRAP2_MOUSE
GRB2-related adaptor protein 2
Search

GRAP2

0.97	growth factor receptor-bound protein 2-like isoform X1

0.61	GO:0038083	peptidyl-tyrosine autophosphorylation
0.57	GO:0045087	innate immune response
0.57	GO:0016477	cell migration
0.57	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.55	GO:0042127	regulation of cell proliferation
0.55	GO:0007265	Ras protein signal transduction
0.53	GO:0030154	cell differentiation
0.40	GO:0038095	Fc-epsilon receptor signaling pathway
0.39	GO:0031295	T cell costimulation
0.39	GO:0050852	T cell receptor signaling pathway

0.58	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.54	GO:0005102	receptor binding
0.39	GO:0005070	SH3/SH2 adaptor activity
0.35	GO:0008289	lipid binding
0.34	GO:0005516	calmodulin binding
0.33	GO:0005085	guanyl-nucleotide exchange factor activity
0.33	GO:0042802	identical protein binding
0.33	GO:0008092	cytoskeletal protein binding
0.33	GO:0017048	Rho GTPase binding
0.33	GO:0043168	anion binding

0.69	GO:0005768	endosome
0.57	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.57	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.35	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:1990528	Rvs161p-Rvs167p complex
0.34	GO:0031097	medial cortex
0.34	GO:0005826	actomyosin contractile ring
0.34	GO:0030479	actin cortical patch
0.34	GO:0005937	mating projection

0.58

EC:2.7.10.2

GO:0004715

sp|O89101|FGF18_MOUSE
Fibroblast growth factor 18
Search

FGF18

0.61	Fibroblast growth factor

0.84	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.59	GO:1904849	positive regulation of cell chemotaxis to fibroblast growth factor
0.58	GO:0001957	intramembranous ossification
0.58	GO:2000544	regulation of endothelial cell chemotaxis to fibroblast growth factor
0.57	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
0.57	GO:2001028	positive regulation of endothelial cell chemotaxis
0.57	GO:0032332	positive regulation of chondrocyte differentiation
0.56	GO:0001958	endochondral ossification
0.56	GO:0002063	chondrocyte development

0.85	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0004713	protein tyrosine kinase activity
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.49	GO:0005730	nucleolus
0.32	GO:0005737	cytoplasm

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|O89103|C1QR1_MOUSE
Complement component C1q receptor
Search

0.70	complement component C1q receptor

0.49	GO:0035583	sequestering of TGFbeta in extracellular matrix
0.48	GO:0006030	chitin metabolic process
0.47	GO:0048048	embryonic eye morphogenesis
0.46	GO:0060346	bone trabecula formation
0.46	GO:0043010	camera-type eye development
0.45	GO:0030501	positive regulation of bone mineralization
0.45	GO:0045669	positive regulation of osteoblast differentiation
0.44	GO:0030326	embryonic limb morphogenesis
0.44	GO:0030198	extracellular matrix organization
0.44	GO:0007155	cell adhesion

0.70	GO:0005509	calcium ion binding
0.63	GO:0005201	extracellular matrix structural constituent
0.48	GO:0001849	complement component C1q binding
0.48	GO:0008061	chitin binding
0.38	GO:0050840	extracellular matrix binding
0.37	GO:0005178	integrin binding
0.36	GO:0016504	peptidase activator activity
0.36	GO:0008201	heparin binding
0.36	GO:0005044	scavenger receptor activity
0.35	GO:0042802	identical protein binding

0.60	GO:0031012	extracellular matrix
0.42	GO:0099512	supramolecular fiber
0.41	GO:0009986	cell surface
0.41	GO:0031982	vesicle
0.40	GO:0005615	extracellular space
0.38	GO:0005886	plasma membrane
0.37	GO:0044444	cytoplasmic part
0.36	GO:0043229	intracellular organelle
0.33	GO:0043230	extracellular organelle
0.33	GO:0012505	endomembrane system

0.35

GO:0004222

sp|O89104|SYPL2_MOUSE
Synaptophysin-like protein 2
Search

SYPL2

0.88	Synaptophysin a

0.54	GO:0006874	cellular calcium ion homeostasis
0.51	GO:0048168	regulation of neuronal synaptic plasticity
0.39	GO:0021762	substantia nigra development
0.33	GO:0055114	oxidation-reduction process

0.82	GO:0008021	synaptic vesicle
0.51	GO:0099501	exocytic vesicle membrane
0.47	GO:0031301	integral component of organelle membrane
0.33	GO:0030141	secretory granule

sp|O89106|FHIT_MOUSE
Bis(5'-adenosyl)-triphosphatase
Search

FHIT

0.50	Fragile histidine triad gene

0.52	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.52	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.42	GO:0006163	purine nucleotide metabolic process
0.37	GO:0015962	diadenosine triphosphate metabolic process
0.36	GO:0015961	diadenosine polyphosphate catabolic process
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:0006355	regulation of transcription, DNA-templated
0.35	GO:0006260	DNA replication
0.35	GO:0009164	nucleoside catabolic process
0.33	GO:0006289	nucleotide-excision repair

0.53	GO:0047710	bis(5'-adenosyl)-triphosphatase activity
0.49	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0042802	identical protein binding
0.35	GO:0043530	adenosine 5'-monophosphoramidase activity
0.35	GO:0016819	hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides
0.34	GO:0016151	nickel cation binding
0.34	GO:1901265	nucleoside phosphate binding
0.34	GO:0036094	small molecule binding
0.33	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0017111	nucleoside-triphosphatase activity

0.50	GO:0001650	fibrillar center
0.45	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.39	GO:0005856	cytoskeleton
0.37	GO:0070062	extracellular exosome
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.53	EC:3.6.1.29	GO:0047710
0.53	KEGG:R00187	GO:0047710

sp|O89109|KCNN4_MOUSE
Intermediate conductance calcium-activated potassium channel protein 4
Search

KCNN4

0.94	Intermediate-conductance calcium-activated potassium channel

0.73	GO:0071805	potassium ion transmembrane transport
0.56	GO:0046541	saliva secretion
0.56	GO:0050862	positive regulation of T cell receptor signaling pathway
0.56	GO:0030322	stabilization of membrane potential
0.54	GO:0006884	cell volume homeostasis
0.53	GO:0050714	positive regulation of protein secretion
0.52	GO:0045332	phospholipid translocation
0.50	GO:0006816	calcium ion transport
0.38	GO:0002376	immune system process
0.34	GO:0006952	defense response

0.85	GO:0016286	small conductance calcium-activated potassium channel activity
0.77	GO:0005516	calmodulin binding
0.53	GO:0019903	protein phosphatase binding
0.38	GO:0022894	Intermediate conductance calcium-activated potassium channel activity
0.34	GO:0005249	voltage-gated potassium channel activity

0.48	GO:0031982	vesicle
0.48	GO:0043025	neuronal cell body
0.43	GO:0005886	plasma membrane
0.36	GO:0034705	potassium channel complex
0.36	GO:0045121	membrane raft
0.36	GO:0045177	apical part of cell
0.33	GO:0005737	cytoplasm

sp|O89110|CASP8_MOUSE
Caspase-8
Search

CASP8

0.90	Caspase 8, apoptosis-related cysteine peptidase

0.78	GO:0006915	apoptotic process
0.73	GO:0042981	regulation of apoptotic process
0.61	GO:0006508	proteolysis
0.61	GO:0045651	positive regulation of macrophage differentiation
0.58	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.58	GO:0071260	cellular response to mechanical stimulus
0.58	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.57	GO:2001056	positive regulation of cysteine-type endopeptidase activity
0.57	GO:0034612	response to tumor necrosis factor
0.51	GO:0007166	cell surface receptor signaling pathway

0.75	GO:0004197	cysteine-type endopeptidase activity
0.63	GO:0035877	death effector domain binding
0.59	GO:0097110	scaffold protein binding
0.55	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0042802	identical protein binding
0.50	GO:0004871	signal transducer activity
0.39	GO:0005123	death receptor binding
0.38	GO:0005164	tumor necrosis factor receptor binding
0.37	GO:0046982	protein heterodimerization activity
0.37	GO:0032403	protein complex binding

0.65	GO:0097342	ripoptosome
0.62	GO:0031265	CD95 death-inducing signaling complex
0.51	GO:0005654	nucleoplasm
0.39	GO:0030690	Noc1p-Noc2p complex
0.37	GO:0044297	cell body
0.37	GO:0098857	membrane microdomain
0.37	GO:0043005	neuron projection
0.36	GO:0005739	mitochondrion
0.35	GO:0031968	organelle outer membrane
0.34	GO:0005856	cytoskeleton

0.75

GO:0004197

sp|O89112|LANC1_MOUSE
LanC-like protein 1
Search

LANCL1

0.96	LanC lantibiotic synthetase component C-like 1 (Bacterial)

0.49

GO:0007165

signal transduction

0.85	GO:0050750	low-density lipoprotein particle receptor binding
0.84	GO:0043295	glutathione binding
0.78	GO:0017124	SH3 domain binding
0.62	GO:0008270	zinc ion binding

0.46

GO:0005886

plasma membrane

sp|O89113|IER5_MOUSE
Immediate early response gene 5 protein
Search

IER5

0.94	Immediate early response 5

0.87	GO:1900036	positive regulation of cellular response to heat
0.80	GO:0034605	cellular response to heat
0.76	GO:0042127	regulation of cell proliferation
0.75	GO:0045944	positive regulation of transcription by RNA polymerase II
0.42	GO:0006351	transcription, DNA-templated

0.73

GO:0042802

identical protein binding

0.80	GO:0000159	protein phosphatase type 2A complex
0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm

sp|O89114|DNJB5_MOUSE
DnaJ homolog subfamily B member 5
Search

DNAJB5

0.97	DnaJ like protein subfamily B member 5

0.68	GO:0006457	protein folding
0.53	GO:0000122	negative regulation of transcription by RNA polymerase II
0.53	GO:0006986	response to unfolded protein
0.43	GO:0090084	negative regulation of inclusion body assembly
0.42	GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress
0.42	GO:0032781	positive regulation of ATPase activity
0.34	GO:0002088	lens development in camera-type eye

0.70	GO:0051082	unfolded protein binding
0.53	GO:0051087	chaperone binding
0.43	GO:0001106	RNA polymerase II transcription corepressor activity
0.43	GO:0030544	Hsp70 protein binding
0.42	GO:0051117	ATPase binding
0.42	GO:0001671	ATPase activator activity
0.41	GO:0045296	cadherin binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.49	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.34	GO:0014069	postsynaptic density
0.34	GO:0070062	extracellular exosome
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044446	intracellular organelle part

sp|O89116|VTI1A_MOUSE
Vesicle transport through interaction with t-SNAREs homolog 1A
Search

VTI1A

0.96	Vesicle transport through interaction with t-SNAREsB

0.67	GO:0006886	intracellular protein transport
0.66	GO:0016192	vesicle-mediated transport
0.58	GO:0050882	voluntary musculoskeletal movement
0.58	GO:0090161	Golgi ribbon formation
0.56	GO:0061025	membrane fusion
0.54	GO:0016482	cytosolic transport
0.53	GO:0016197	endosomal transport
0.52	GO:0006914	autophagy
0.46	GO:0072666	establishment of protein localization to vacuole
0.45	GO:0048284	organelle fusion

0.64	GO:0005484	SNAP receptor activity
0.45	GO:0000149	SNARE binding

0.57	GO:0005794	Golgi apparatus
0.55	GO:0005776	autophagosome
0.49	GO:0005829	cytosol
0.46	GO:0031902	late endosome membrane
0.46	GO:0031201	SNARE complex
0.45	GO:0012507	ER to Golgi transport vesicle membrane
0.42	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0044306	neuron projection terminus
0.38	GO:0008021	synaptic vesicle
0.38	GO:0043025	neuronal cell body

sp|P00015|CYC2_MOUSE
Cytochrome c, testis-specific
Search

CYCS

0.67	Cytochrome c, somatic A

0.61	GO:0022900	electron transport chain
0.55	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.46	GO:0006119	oxidative phosphorylation
0.46	GO:0009060	aerobic respiration
0.42	GO:0006915	apoptotic process
0.42	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process
0.42	GO:0042743	hydrogen peroxide metabolic process
0.42	GO:0034465	response to carbon monoxide
0.41	GO:1901857	positive regulation of cellular respiration
0.41	GO:0002931	response to ischemia

0.63	GO:0020037	heme binding
0.62	GO:0009055	electron transfer activity
0.54	GO:0046872	metal ion binding
0.38	GO:0019899	enzyme binding

0.62	GO:0070469	respiratory chain
0.61	GO:0005739	mitochondrion
0.60	GO:0031970	organelle envelope lumen
0.48	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.43	GO:0043209	myelin sheath

sp|P00158|CYB_MOUSE
Cytochrome b
Search

CYTB

0.41	Cytochrome b

0.73	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c
0.37	GO:0033590	response to cobalamin
0.37	GO:0033762	response to glucagon
0.36	GO:0055093	response to hyperoxia
0.36	GO:0031100	animal organ regeneration
0.36	GO:0042538	hyperosmotic salinity response
0.36	GO:0045471	response to ethanol
0.36	GO:0051592	response to calcium ion
0.36	GO:0046686	response to cadmium ion
0.36	GO:0001666	response to hypoxia

0.73	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.62	GO:0009055	electron transfer activity
0.54	GO:0046872	metal ion binding
0.35	GO:0032403	protein complex binding

0.72	GO:0045275	respiratory chain complex III
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.35	GO:0031301	integral component of organelle membrane

0.73

EC:1.10.2

GO:0016681

sp|P00184|CP1A1_MOUSE
Cytochrome P450 1A1
Search

sp|P00186|CP1A2_MOUSE
Cytochrome P450 1A2
Search

sp|P00329|ADH1_MOUSE
Alcohol dehydrogenase 1
Search

0.38	Alcohol dehydrogenase E chain

0.53	GO:0055114	oxidation-reduction process
0.49	GO:0006067	ethanol metabolic process
0.47	GO:0033574	response to testosterone
0.47	GO:0042573	retinoic acid metabolic process
0.47	GO:0045471	response to ethanol
0.47	GO:0042572	retinol metabolic process
0.46	GO:0032526	response to retinoic acid
0.46	GO:0034310	primary alcohol catabolic process
0.45	GO:0030534	adult behavior
0.44	GO:0048545	response to steroid hormone

0.62	GO:0008270	zinc ion binding
0.56	GO:0004022	alcohol dehydrogenase (NAD) activity
0.43	GO:0042803	protein homodimerization activity
0.40	GO:0004745	retinol dehydrogenase activity
0.39	GO:0035276	ethanol binding
0.37	GO:0004031	aldehyde oxidase activity
0.37	GO:0019841	retinol binding
0.36	GO:0048019	receptor antagonist activity
0.33	GO:0051287	NAD binding

0.42	GO:0005829	cytosol
0.42	GO:0005654	nucleoplasm
0.39	GO:0005739	mitochondrion
0.38	GO:0005886	plasma membrane
0.35	GO:0005576	extracellular region
0.33	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

0.56

EC:1.1.1.1

GO:0004022

sp|P00342|LDHC_MOUSE
L-lactate dehydrogenase C chain
Search

0.53	L-lactate dehydrogenase C chain

0.60	GO:0005975	carbohydrate metabolic process
0.57	GO:0019752	carboxylic acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0030317	flagellated sperm motility
0.46	GO:1901617	organic hydroxy compound biosynthetic process
0.45	GO:0006754	ATP biosynthetic process
0.42	GO:0016053	organic acid biosynthetic process
0.37	GO:0019674	NAD metabolic process
0.37	GO:0051591	response to cAMP
0.37	GO:0043627	response to estrogen

0.81	GO:0004459	L-lactate dehydrogenase activity
0.42	GO:0042802	identical protein binding
0.39	GO:0045296	cadherin binding
0.38	GO:0019900	kinase binding
0.36	GO:0051287	NAD binding

0.49	GO:0031514	motile cilium
0.48	GO:0005737	cytoplasm
0.42	GO:0043209	myelin sheath
0.42	GO:0045121	membrane raft
0.38	GO:0070062	extracellular exosome
0.37	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0097223	sperm part
0.35	GO:0044441	ciliary part
0.30	GO:0016021	integral component of membrane

0.81

EC:1.1.1.27

GO:0004459

sp|P00375|DYR_MOUSE
Dihydrofolate reductase
Search

DHFR

0.42	Viral dihydrofolate reductase

0.75	GO:0046654	tetrahydrofolate biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0051000	positive regulation of nitric-oxide synthase activity
0.49	GO:2000121	regulation of removal of superoxide radicals
0.48	GO:0046146	tetrahydrobiopterin metabolic process
0.48	GO:0034312	diol biosynthetic process
0.46	GO:0031427	response to methotrexate
0.44	GO:0003232	bulbus arteriosus development
0.43	GO:0046452	dihydrofolate metabolic process
0.43	GO:0046655	folic acid metabolic process

0.79	GO:0004146	dihydrofolate reductase activity
0.45	GO:0051870	methotrexate binding
0.44	GO:1990825	sequence-specific mRNA binding
0.43	GO:0000900	translation repressor activity, nucleic acid binding
0.42	GO:0005542	folic acid binding
0.41	GO:0070402	NADPH binding
0.41	GO:0051871	dihydrofolic acid binding
0.36	GO:0033560	folate reductase activity
0.33	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0004386	helicase activity

0.43	GO:0005739	mitochondrion
0.35	GO:0005829	cytosol
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0019866	organelle inner membrane
0.34	GO:0000439	core TFIIH complex
0.30	GO:0016021	integral component of membrane

0.79

EC:1.5.1.3

GO:0004146

sp|P00397|COX1_MOUSE
Cytochrome c oxidase subunit 1
Search

COX1

0.30	Cytochrome c oxidase subunit 1

0.64	GO:0006119	oxidative phosphorylation
0.64	GO:0009060	aerobic respiration
0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.38	GO:0051602	response to electrical stimulus
0.37	GO:0021549	cerebellum development
0.37	GO:0046688	response to copper ion
0.37	GO:0007568	aging
0.35	GO:0006979	response to oxidative stress

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0020037	heme binding
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.63	GO:0005506	iron ion binding
0.62	GO:0009055	electron transfer activity

0.75	GO:0045277	respiratory chain complex IV
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.38	GO:0098798	mitochondrial protein complex
0.38	GO:0045275	respiratory chain complex III
0.30	GO:0016021	integral component of membrane

0.65

EC:1.9.3

GO:0016676

sp|P00405|COX2_MOUSE
Cytochrome c oxidase subunit 2
Search

COX2

0.44	Cytochrome c oxidase subunit 2

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.38	GO:0007595	lactation
0.37	GO:0009409	response to cold
0.34	GO:0006119	oxidative phosphorylation
0.34	GO:0045333	cellular respiration

0.72	GO:0005507	copper ion binding
0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.49	GO:0070069	cytochrome complex
0.45	GO:0098796	membrane protein complex
0.35	GO:0098798	mitochondrial protein complex
0.34	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.65

EC:1.9.3

GO:0016676

sp|P00416|COX3_MOUSE
Cytochrome c oxidase subunit 3
Search

COX3

0.44	Cytochrome c oxidase subunit 3

0.76	GO:0019646	aerobic electron transport chain
0.63	GO:1902600	hydrogen ion transmembrane transport
0.40	GO:0008535	respiratory chain complex IV assembly

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.61	GO:0005739	mitochondrion
0.38	GO:0045277	respiratory chain complex IV
0.34	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.65

EC:1.9.3

GO:0016676

sp|P00493|HPRT_MOUSE
Hypoxanthine-guanine phosphoribosyltransferase
Search

HPRT1

0.50	Hypoxanthine-guanine phosphoribosyltransferase

0.78	GO:0032264	IMP salvage
0.75	GO:0006166	purine ribonucleoside salvage
0.59	GO:0046038	GMP catabolic process
0.58	GO:0006178	guanine salvage
0.58	GO:0045964	positive regulation of dopamine metabolic process
0.55	GO:0051289	protein homotetramerization
0.54	GO:0046100	hypoxanthine metabolic process
0.54	GO:0007625	grooming behavior
0.54	GO:0021756	striatum development
0.54	GO:0001975	response to amphetamine

0.79	GO:0052657	guanine phosphoribosyltransferase activity
0.79	GO:0004422	hypoxanthine phosphoribosyltransferase activity
0.53	GO:0046872	metal ion binding
0.52	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.50	GO:0042803	protein homodimerization activity

0.48	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.33	GO:0005694	chromosome

0.79	EC:2.4.2.8	GO:0052657
0.79	KEGG:R01229	GO:0052657

sp|P00520|ABL1_MOUSE
Tyrosine-protein kinase ABL1
Search

ABL1

0.57	Tyrosine-protein kinase

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.61	GO:1904531	positive regulation of actin filament binding
0.61	GO:1900275	negative regulation of phospholipase C activity
0.61	GO:0002333	transitional one stage B cell differentiation
0.60	GO:1990051	activation of protein kinase C activity
0.60	GO:0038189	neuropilin signaling pathway
0.60	GO:1905555	positive regulation blood vessel branching
0.60	GO:1904528	positive regulation of microtubule binding
0.60	GO:0090135	actin filament branching
0.60	GO:1905244	regulation of modification of synaptic structure

0.81	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.59	GO:0038191	neuropilin binding
0.58	GO:0070064	proline-rich region binding
0.58	GO:0051019	mitogen-activated protein kinase binding
0.58	GO:0042169	SH2 domain binding
0.58	GO:0005080	protein kinase C binding
0.57	GO:0001784	phosphotyrosine residue binding
0.56	GO:0046875	ephrin receptor binding
0.55	GO:0019905	syntaxin binding
0.55	GO:0008022	protein C-terminus binding

0.54	GO:0031252	cell leading edge
0.53	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0016604	nuclear body
0.51	GO:0005730	nucleolus
0.51	GO:0015629	actin cytoskeleton
0.49	GO:0005829	cytosol
0.47	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.44	GO:0043234	protein complex
0.41	GO:0043005	neuron projection
0.41	GO:0043025	neuronal cell body

0.81

EC:2.7.10.2

GO:0004715

sp|P00536|MOS_MOUSE
Proto-oncogene serine/threonine-protein kinase mos
Search

MOS

0.51	Serine/threonine-protein kinase-transforming protein mos

0.63	GO:0006468	protein phosphorylation
0.47	GO:1902103	negative regulation of metaphase/anaphase transition of meiotic cell cycle
0.45	GO:0051296	establishment of meiotic spindle orientation
0.44	GO:0043410	positive regulation of MAPK cascade
0.43	GO:0000212	meiotic spindle organization
0.42	GO:0043405	regulation of MAP kinase activity
0.42	GO:0032147	activation of protein kinase activity
0.42	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.40	GO:0006325	chromatin organization
0.39	GO:0035556	intracellular signal transduction

0.64	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0005057	signal transducer activity, downstream of receptor
0.35	GO:0004713	protein tyrosine kinase activity
0.34	GO:0005198	structural molecule activity
0.33	GO:0005515	protein binding
0.32	GO:0003723	RNA binding

0.35	GO:0005737	cytoplasm
0.35	GO:0019028	viral capsid
0.34	GO:0036338	viral membrane
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044446	intracellular organelle part

0.64

GO:0004674

sp|P00683|RNAS1_MOUSE
Ribonuclease pancreatic
Search

RNASE1

0.47	RNase1 alpha

0.63

GO:0090305

nucleic acid phosphodiester bond hydrolysis

0.65	GO:0004519	endonuclease activity
0.51	GO:0003676	nucleic acid binding

sp|P00687|AMY1_MOUSE
Alpha-amylase 1
Search

0.43	Pancreatic alpha-amylase

0.60	GO:0005975	carbohydrate metabolic process
0.38	GO:0007586	digestion
0.36	GO:1901575	organic substance catabolic process

0.81	GO:0103025	alpha-amylase activity (releasing maltohexaose)
0.80	GO:0004556	alpha-amylase activity
0.53	GO:0043169	cation binding
0.41	GO:0031404	chloride ion binding
0.34	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.42	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle

0.80

EC:3.2.1.1

GO:0004556

sp|P00688|AMYP_MOUSE
Pancreatic alpha-amylase
Search

0.43	Pancreatic alpha-amylase

0.60	GO:0005975	carbohydrate metabolic process
0.37	GO:0007586	digestion
0.36	GO:1901575	organic substance catabolic process

0.81	GO:0103025	alpha-amylase activity (releasing maltohexaose)
0.80	GO:0004556	alpha-amylase activity
0.53	GO:0043169	cation binding
0.41	GO:0031404	chloride ion binding
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.41	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle

0.80

EC:3.2.1.1

GO:0004556

sp|P00755|K1KB1_MOUSE
Kallikrein 1-related peptidase b1
Search

0.97	Epidermal growth factor-binding protein type A

0.61	GO:0006508	proteolysis
0.40	GO:0002675	positive regulation of acute inflammatory response
0.39	GO:0007584	response to nutrient
0.39	GO:0051604	protein maturation
0.38	GO:0008284	positive regulation of cell proliferation
0.38	GO:0043065	positive regulation of apoptotic process
0.38	GO:0009405	pathogenesis
0.38	GO:0008015	blood circulation
0.38	GO:0002936	bradykinin biosynthetic process
0.38	GO:0002255	tissue kallikrein-kinin cascade

0.69	GO:0004252	serine-type endopeptidase activity
0.43	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.39	GO:0090729	toxin activity
0.38	GO:0005057	signal transducer activity, downstream of receptor
0.37	GO:0005102	receptor binding
0.36	GO:0030545	receptor regulator activity
0.35	GO:0005044	scavenger receptor activity
0.34	GO:0046872	metal ion binding
0.34	GO:0019899	enzyme binding
0.33	GO:0043395	heparan sulfate proteoglycan binding

0.48	GO:0005615	extracellular space
0.41	GO:0030141	secretory granule
0.40	GO:1903561	extracellular vesicle
0.40	GO:0043234	protein complex
0.40	GO:0005634	nucleus
0.39	GO:0097223	sperm part
0.38	GO:0045177	apical part of cell
0.36	GO:0005766	primary lysosome
0.35	GO:0060205	cytoplasmic vesicle lumen
0.35	GO:0005775	vacuolar lumen

0.69

GO:0004252

sp|P00756|K1KB3_MOUSE
Kallikrein 1-related peptidase b3
Search

0.97	Epidermal growth factor-binding protein type A

0.61	GO:0006508	proteolysis
0.40	GO:0002778	antibacterial peptide production
0.39	GO:0002675	positive regulation of acute inflammatory response
0.38	GO:0007584	response to nutrient
0.38	GO:0051604	protein maturation
0.38	GO:0008284	positive regulation of cell proliferation
0.38	GO:0043065	positive regulation of apoptotic process
0.37	GO:0009405	pathogenesis
0.37	GO:0008015	blood circulation
0.36	GO:0002936	bradykinin biosynthetic process

0.69	GO:0004252	serine-type endopeptidase activity
0.43	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.38	GO:0090729	toxin activity
0.37	GO:0005057	signal transducer activity, downstream of receptor
0.36	GO:0005102	receptor binding
0.36	GO:0030545	receptor regulator activity
0.34	GO:0046872	metal ion binding
0.33	GO:0019899	enzyme binding
0.32	GO:0043395	heparan sulfate proteoglycan binding
0.32	GO:0008201	heparin binding

0.48	GO:0005615	extracellular space
0.40	GO:1903561	extracellular vesicle
0.40	GO:0043234	protein complex
0.40	GO:0030141	secretory granule
0.40	GO:0005634	nucleus
0.38	GO:0097223	sperm part
0.38	GO:0045177	apical part of cell
0.35	GO:0005766	primary lysosome
0.35	GO:0060205	cytoplasmic vesicle lumen
0.34	GO:0005775	vacuolar lumen

0.69

GO:0004252

sp|P00757|K1KB4_MOUSE
Kallikrein 1-related peptidase-like b4
Search

0.97	Epidermal growth factor-binding protein type A

0.61	GO:0006508	proteolysis
0.40	GO:0002675	positive regulation of acute inflammatory response
0.39	GO:0007584	response to nutrient
0.39	GO:0008284	positive regulation of cell proliferation
0.38	GO:0051604	protein maturation
0.38	GO:0043065	positive regulation of apoptotic process
0.38	GO:0008015	blood circulation
0.37	GO:0002936	bradykinin biosynthetic process
0.37	GO:0002255	tissue kallikrein-kinin cascade
0.37	GO:0010469	regulation of receptor activity

0.69	GO:0004252	serine-type endopeptidase activity
0.43	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.38	GO:0005057	signal transducer activity, downstream of receptor
0.37	GO:0008083	growth factor activity
0.35	GO:0046872	metal ion binding
0.34	GO:0090729	toxin activity
0.33	GO:0019899	enzyme binding

0.48	GO:0005615	extracellular space
0.42	GO:0030141	secretory granule
0.41	GO:1903561	extracellular vesicle
0.40	GO:0005634	nucleus
0.40	GO:0043234	protein complex
0.39	GO:0097223	sperm part
0.39	GO:0045177	apical part of cell
0.34	GO:0005766	primary lysosome
0.34	GO:0060205	cytoplasmic vesicle lumen
0.34	GO:0005775	vacuolar lumen

0.69

GO:0004252

sp|P00796|RENI2_MOUSE
Renin-2
Search

REN

0.97

Pro-renin

0.61	GO:0006508	proteolysis
0.59	GO:0002002	regulation of angiotensin levels in blood
0.58	GO:0002018	renin-angiotensin regulation of aldosterone production
0.57	GO:0042756	drinking behavior
0.54	GO:0001823	mesonephros development
0.54	GO:0008584	male gonad development
0.53	GO:0042445	hormone metabolic process
0.53	GO:0048469	cell maturation
0.51	GO:0051604	protein maturation
0.51	GO:0043408	regulation of MAPK cascade

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.48	GO:0005102	receptor binding
0.35	GO:0070492	oligosaccharide binding
0.35	GO:0097718	disordered domain specific binding
0.34	GO:0004983	neuropeptide Y receptor activity

0.52	GO:0045177	apical part of cell
0.49	GO:0005615	extracellular space
0.37	GO:0005622	intracellular
0.34	GO:0043227	membrane-bounded organelle
0.33	GO:0005578	proteinaceous extracellular matrix
0.33	GO:0071944	cell periphery
0.33	GO:0043234	protein complex
0.32	GO:0012505	endomembrane system
0.32	GO:0044422	organelle part
0.30	GO:0016020	membrane

sp|P00848|ATP6_MOUSE
ATP synthase subunit a
Search

ATP6

0.42	ATP synthase subunit a

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.38	GO:0055093	response to hyperoxia
0.37	GO:0007568	aging

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.38	GO:0016887	ATPase activity

0.72	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.42	GO:0098798	mitochondrial protein complex
0.34	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.38

GO:0016887

sp|P00860|DCOR_MOUSE
Ornithine decarboxylase
Search

ODC1

0.48	Ornithine decarboxylase

0.74	GO:0006596	polyamine biosynthetic process
0.57	GO:0009445	putrescine metabolic process
0.55	GO:0001822	kidney development
0.54	GO:0006591	ornithine metabolic process
0.54	GO:0042176	regulation of protein catabolic process
0.54	GO:0008284	positive regulation of cell proliferation
0.53	GO:0009615	response to virus
0.44	GO:0042462	eye photoreceptor cell development
0.35	GO:0006521	regulation of cellular amino acid metabolic process

0.60	GO:0004586	ornithine decarboxylase activity
0.53	GO:0042803	protein homodimerization activity

0.49	GO:0005829	cytosol
0.39	GO:0048471	perinuclear region of cytoplasm

0.60	EC:4.1.1.17	GO:0004586
0.60	KEGG:R00670	GO:0004586

sp|P00920|CAH2_MOUSE
Carbonic anhydrase 2
Search

CA2

0.43	Red blood cell carbonic anhydrase II

0.71	GO:0006730	one-carbon metabolic process
0.56	GO:0015670	carbon dioxide transport
0.55	GO:0038166	angiotensin-activated signaling pathway
0.55	GO:2000878	positive regulation of oligopeptide transport
0.55	GO:2001148	regulation of dipeptide transmembrane transport
0.54	GO:0044070	regulation of anion transport
0.52	GO:0032849	positive regulation of cellular pH reduction
0.51	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.50	GO:0034764	positive regulation of transmembrane transport
0.47	GO:0002009	morphogenesis of an epithelium

0.77	GO:0004089	carbonate dehydratase activity
0.63	GO:0008270	zinc ion binding
0.55	GO:0004064	arylesterase activity
0.34	GO:0005515	protein binding

0.52	GO:0045177	apical part of cell
0.48	GO:0043209	myelin sheath
0.43	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.39	GO:0005902	microvillus
0.39	GO:0030424	axon
0.37	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.77

EC:4.2.1.1

GO:0004089

sp|P01027|CO3_MOUSE
Complement C3
Search

0.90	Cobra venom factor

0.84	GO:0006956	complement activation
0.75	GO:0010951	negative regulation of endopeptidase activity
0.66	GO:0006954	inflammatory response
0.58	GO:0001970	positive regulation of activation of membrane attack complex
0.58	GO:0002894	positive regulation of type II hypersensitivity
0.58	GO:0001796	regulation of type IIa hypersensitivity
0.57	GO:0010866	regulation of triglyceride biosynthetic process
0.57	GO:0097242	amyloid-beta clearance
0.57	GO:0010884	positive regulation of lipid storage
0.57	GO:2000427	positive regulation of apoptotic cell clearance

0.75	GO:0004866	endopeptidase inhibitor activity
0.61	GO:0031715	C5L2 anaphylatoxin chemotactic receptor binding
0.38	GO:0090729	toxin activity
0.36	GO:0005164	tumor necrosis factor receptor binding
0.35	GO:0004252	serine-type endopeptidase activity
0.35	GO:0008289	lipid binding
0.34	GO:0046872	metal ion binding
0.33	GO:0048037	cofactor binding
0.32	GO:0016491	oxidoreductase activity

0.73	GO:0005615	extracellular space
0.43	GO:0043234	protein complex
0.37	GO:1903561	extracellular vesicle
0.36	GO:0035578	azurophil granule lumen
0.35	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0004252

sp|P01029|CO4B_MOUSE
Complement C4-B
Search

0.95	Complement component 4

0.76	GO:0006956	complement activation
0.74	GO:0010951	negative regulation of endopeptidase activity
0.71	GO:0006954	inflammatory response
0.57	GO:0016064	immunoglobulin mediated immune response
0.42	GO:2000427	positive regulation of apoptotic cell clearance
0.42	GO:0045087	innate immune response
0.40	GO:0030449	regulation of complement activation
0.40	GO:0032490	detection of molecule of bacterial origin
0.37	GO:0008228	opsonization
0.36	GO:0043687	post-translational protein modification

0.75	GO:0004866	endopeptidase inhibitor activity
0.44	GO:0001848	complement binding
0.43	GO:0001846	opsonin binding
0.38	GO:0030246	carbohydrate binding
0.37	GO:0004252	serine-type endopeptidase activity
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.34	GO:0020037	heme binding
0.34	GO:0005506	iron ion binding

0.71	GO:0005615	extracellular space
0.44	GO:0030425	dendrite
0.44	GO:0030424	axon
0.42	GO:0045202	synapse
0.41	GO:0030054	cell junction
0.41	GO:0043025	neuronal cell body
0.40	GO:1903561	extracellular vesicle
0.37	GO:0044216	other organism cell
0.36	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0005886	plasma membrane

0.37

GO:0004252

sp|P01101|FOS_MOUSE
Proto-oncogene c-Fos
Search

FOS

0.96	Proto-oncogene protein c-FOS

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.62	GO:0035994	response to muscle stretch
0.62	GO:0045672	positive regulation of osteoclast differentiation
0.60	GO:0071277	cellular response to calcium ion
0.60	GO:0035914	skeletal muscle cell differentiation
0.60	GO:0071276	cellular response to cadmium ion
0.60	GO:0060395	SMAD protein signal transduction
0.58	GO:0007179	transforming growth factor beta receptor signaling pathway
0.55	GO:0006366	transcription by RNA polymerase II
0.54	GO:0034614	cellular response to reactive oxygen species

0.61	GO:0070412	R-SMAD binding
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.60	GO:0001102	RNA polymerase II activating transcription factor binding
0.60	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.57	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0003682	chromatin binding
0.54	GO:0046982	protein heterodimerization activity
0.33	GO:0005198	structural molecule activity

0.74	GO:0005667	transcription factor complex
0.52	GO:0032993	protein-DNA complex
0.52	GO:0005654	nucleoplasm
0.43	GO:0005783	endoplasmic reticulum
0.42	GO:0005829	cytosol
0.39	GO:0043005	neuron projection
0.35	GO:0042025	host cell nucleus
0.33	GO:0019028	viral capsid
0.30	GO:0016020	membrane

sp|P01108|MYC_MOUSE
Myc proto-oncogene protein
Search

MYC

0.93	MYC proto-oncogene, bHLH transcription factor

0.57	GO:0006355	regulation of transcription, DNA-templated
0.56	GO:0045656	negative regulation of monocyte differentiation
0.55	GO:0048146	positive regulation of fibroblast proliferation
0.54	GO:0010332	response to gamma radiation
0.54	GO:2000573	positive regulation of DNA biosynthetic process
0.53	GO:0060070	canonical Wnt signaling pathway
0.53	GO:2001022	positive regulation of response to DNA damage stimulus
0.53	GO:0032204	regulation of telomere maintenance
0.53	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.53	GO:0050679	positive regulation of epithelial cell proliferation

0.61	GO:0003700	DNA binding transcription factor activity
0.61	GO:0046983	protein dimerization activity
0.55	GO:0070888	E-box binding
0.49	GO:0032403	protein complex binding
0.39	GO:0070491	repressing transcription factor binding
0.39	GO:0033613	activating transcription factor binding
0.39	GO:0071074	eukaryotic initiation factor eIF2 binding
0.37	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0003729	mRNA binding

0.61	GO:0005634	nucleus
0.51	GO:0070013	intracellular organelle lumen
0.45	GO:0044446	intracellular organelle part
0.42	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0005791	rough endoplasmic reticulum
0.37	GO:0030424	axon
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0042025	host cell nucleus
0.35	GO:0005739	mitochondrion
0.35	GO:0043234	protein complex

sp|P01132|EGF_MOUSE
Pro-epidermal growth factor
Search

EGF

0.97	Pro-epidermal growth factor

0.72	GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification
0.66	GO:0060070	canonical Wnt signaling pathway
0.62	GO:0010469	regulation of receptor activity
0.61	GO:0007262	STAT protein import into nucleus
0.59	GO:1900127	positive regulation of hyaluronan biosynthetic process
0.59	GO:0090370	negative regulation of cholesterol efflux
0.58	GO:0035413	positive regulation of catenin import into nucleus
0.58	GO:0021940	positive regulation of cerebellar granule cell precursor proliferation
0.57	GO:0070371	ERK1 and ERK2 cascade
0.57	GO:0002092	positive regulation of receptor internalization

0.70	GO:0005509	calcium ion binding
0.68	GO:0017147	Wnt-protein binding
0.67	GO:0042813	Wnt-activated receptor activity
0.64	GO:0008083	growth factor activity
0.56	GO:0005154	epidermal growth factor receptor binding
0.40	GO:0004713	protein tyrosine kinase activity
0.37	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.37	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0016504	peptidase activator activity

0.63	GO:0043235	receptor complex
0.54	GO:0070062	extracellular exosome
0.43	GO:0005886	plasma membrane
0.38	GO:0005765	lysosomal membrane
0.37	GO:0031093	platelet alpha granule lumen
0.36	GO:0031012	extracellular matrix
0.36	GO:0030665	clathrin-coated vesicle membrane
0.34	GO:0031429	box H/ACA snoRNP complex
0.30	GO:0016021	integral component of membrane

0.40	EC:2.7.10	GO:0004713
0.37	KEGG:R04545	GO:0046934

sp|P01139|NGF_MOUSE
Beta-nerve growth factor
Search

NGF

0.75	Beta-nerve growth factor

0.75	GO:0010469	regulation of receptor activity
0.52	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors
0.50	GO:0010951	negative regulation of endopeptidase activity
0.49	GO:0048812	neuron projection morphogenesis
0.46	GO:0010628	positive regulation of gene expression
0.44	GO:0043524	negative regulation of neuron apoptotic process
0.43	GO:0045664	regulation of neuron differentiation
0.43	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.41	GO:0007267	cell-cell signaling
0.38	GO:0038179	neurotrophin signaling pathway

0.78	GO:0008083	growth factor activity
0.56	GO:0005163	nerve growth factor receptor binding
0.54	GO:0008191	metalloendopeptidase inhibitor activity
0.38	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.36	GO:0005057	signal transducer activity, downstream of receptor
0.36	GO:0038177	death receptor agonist activity
0.35	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.33	GO:0042802	identical protein binding

0.42	GO:0005576	extracellular region
0.41	GO:0031410	cytoplasmic vesicle
0.37	GO:0005796	Golgi lumen
0.37	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0044306	neuron projection terminus
0.30	GO:0016020	membrane

sp|P01173|WAP_MOUSE
Whey acidic protein
Search

WAP

0.83	Whey acidic protein (Fragment)

0.76

GO:0010466

negative regulation of peptidase activity

0.76	GO:0030414	peptidase inhibitor activity
0.51	GO:0045735	nutrient reservoir activity

0.66

GO:0005576

extracellular region

sp|P01193|COLI_MOUSE
Pro-opiomelanocortin
Search

POMC

0.56	Proopiomelanocortin (Adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin)

0.75	GO:0010469	regulation of receptor activity
0.59	GO:2000852	regulation of corticosterone secretion
0.56	GO:0032098	regulation of appetite
0.56	GO:0032720	negative regulation of tumor necrosis factor production
0.55	GO:0070873	regulation of glycogen metabolic process
0.55	GO:0033059	cellular pigmentation
0.53	GO:0008217	regulation of blood pressure
0.52	GO:0042593	glucose homeostasis
0.50	GO:0007267	cell-cell signaling
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II

0.78	GO:0005179	hormone activity
0.59	GO:0070996	type 1 melanocortin receptor binding
0.58	GO:0031781	type 3 melanocortin receptor binding
0.58	GO:0031782	type 4 melanocortin receptor binding

0.66	GO:0005576	extracellular region
0.53	GO:0030141	secretory granule
0.36	GO:0060205	cytoplasmic vesicle lumen
0.35	GO:0031907	microbody lumen
0.35	GO:0044439	peroxisomal part

sp|P01216|GLHA_MOUSE
Glycoprotein hormones alpha chain
Search

CGA

0.93	Glycoprotein hormones alpha chain

0.76	GO:0010469	regulation of receptor activity
0.54	GO:0046884	follicle-stimulating hormone secretion
0.53	GO:0032275	luteinizing hormone secretion
0.52	GO:0006590	thyroid hormone generation
0.52	GO:0030878	thyroid gland development
0.51	GO:0046621	negative regulation of organ growth
0.49	GO:0008406	gonad development
0.48	GO:0048589	developmental growth
0.47	GO:0032870	cellular response to hormone stimulus
0.34	GO:0006702	androgen biosynthetic process

0.79	GO:0005179	hormone activity
0.44	GO:0046982	protein heterodimerization activity
0.35	GO:0008083	growth factor activity

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|P01325|INS1_MOUSE
Insulin-1
Search

INS

0.95

Insulin

0.76	GO:0010469	regulation of receptor activity
0.70	GO:0006006	glucose metabolic process
0.51	GO:0045818	negative regulation of glycogen catabolic process
0.50	GO:0010243	response to organonitrogen compound
0.50	GO:0050995	negative regulation of lipid catabolic process
0.50	GO:0033861	negative regulation of NAD(P)H oxidase activity
0.50	GO:1902952	positive regulation of dendritic spine maintenance
0.50	GO:0060266	negative regulation of respiratory burst involved in inflammatory response
0.50	GO:0046628	positive regulation of insulin receptor signaling pathway
0.50	GO:0002674	negative regulation of acute inflammatory response

0.79	GO:0005179	hormone activity
0.53	GO:0005159	insulin-like growth factor receptor binding
0.51	GO:0005158	insulin receptor binding
0.49	GO:0002020	protease binding
0.45	GO:0042802	identical protein binding
0.37	GO:0051087	chaperone binding

0.66	GO:0005576	extracellular region
0.42	GO:0030141	secretory granule
0.40	GO:0060205	cytoplasmic vesicle lumen
0.38	GO:0005829	cytosol
0.37	GO:0005732	small nucleolar ribonucleoprotein complex
0.36	GO:0031904	endosome lumen
0.36	GO:0005796	Golgi lumen
0.35	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0030133	transport vesicle

sp|P01326|INS2_MOUSE
Insulin-2
Search

INS

0.95

Insulin

0.76	GO:0010469	regulation of receptor activity
0.71	GO:0006006	glucose metabolic process
0.50	GO:0045818	negative regulation of glycogen catabolic process
0.50	GO:0010243	response to organonitrogen compound
0.50	GO:0050995	negative regulation of lipid catabolic process
0.50	GO:0033861	negative regulation of NAD(P)H oxidase activity
0.50	GO:1902952	positive regulation of dendritic spine maintenance
0.50	GO:0060266	negative regulation of respiratory burst involved in inflammatory response
0.49	GO:2000252	negative regulation of feeding behavior
0.49	GO:0046628	positive regulation of insulin receptor signaling pathway

0.79	GO:0005179	hormone activity
0.53	GO:0005159	insulin-like growth factor receptor binding
0.51	GO:0005158	insulin receptor binding
0.49	GO:0002020	protease binding
0.44	GO:0042802	identical protein binding
0.36	GO:0051087	chaperone binding

0.66	GO:0005576	extracellular region
0.42	GO:0030141	secretory granule
0.40	GO:0060205	cytoplasmic vesicle lumen
0.37	GO:0005829	cytosol
0.37	GO:0005732	small nucleolar ribonucleoprotein complex
0.36	GO:0031904	endosome lumen
0.36	GO:0005796	Golgi lumen
0.35	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.35	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0005634	nucleus

sp|P01572|IFNA1_MOUSE
Interferon alpha-1
Search

0.95	Interferon alpha-B

0.78	GO:0051607	defense response to virus
0.75	GO:0010469	regulation of receptor activity
0.57	GO:0002323	natural killer cell activation involved in immune response
0.57	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.56	GO:0042100	B cell proliferation
0.56	GO:0002286	T cell activation involved in immune response
0.55	GO:0043330	response to exogenous dsRNA
0.55	GO:0030183	B cell differentiation
0.53	GO:0002250	adaptive immune response
0.53	GO:0006959	humoral immune response

0.80	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.50	GO:0032403	protein complex binding

0.73	GO:0005615	extracellular space
0.32	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|P01573|IFNA2_MOUSE
Interferon alpha-2
Search

0.94	Interferon alpha B

0.78	GO:0051607	defense response to virus
0.75	GO:0010469	regulation of receptor activity
0.61	GO:0002323	natural killer cell activation involved in immune response
0.61	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.60	GO:0042100	B cell proliferation
0.59	GO:0002286	T cell activation involved in immune response
0.58	GO:0043330	response to exogenous dsRNA
0.58	GO:0030183	B cell differentiation
0.57	GO:0002250	adaptive immune response
0.56	GO:0006959	humoral immune response

0.80	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.53	GO:0032403	protein complex binding

0.73	GO:0005615	extracellular space
0.32	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|P01575|IFNB_MOUSE
Interferon beta
Search

IFNB1

0.97	Interferon beta

0.77	GO:0051607	defense response to virus
0.75	GO:0010469	regulation of receptor activity
0.67	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.65	GO:0042113	B cell activation
0.65	GO:0043331	response to dsRNA
0.64	GO:0002285	lymphocyte activation involved in immune response
0.64	GO:2000552	negative regulation of T-helper 2 cell cytokine production
0.62	GO:0060337	type I interferon signaling pathway
0.61	GO:0035458	cellular response to interferon-beta
0.60	GO:0046651	lymphocyte proliferation

0.80	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.58	GO:0008811	chloramphenicol O-acetyltransferase activity
0.54	GO:0032403	protein complex binding

0.73

GO:0005615

extracellular space

0.58	EC:2.3.1.28	GO:0008811
0.58	KEGG:R03065	GO:0008811

sp|P01580|IFNG_MOUSE
Interferon gamma
Search

IFNG

0.75	Interferon gamma

0.74	GO:0006955	immune response
0.71	GO:0040008	regulation of growth
0.70	GO:0051607	defense response to virus
0.68	GO:0010469	regulation of receptor activity
0.55	GO:0060552	positive regulation of fructose 1,6-bisphosphate metabolic process
0.55	GO:0060550	positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity
0.55	GO:0032834	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response
0.55	GO:2000309	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production
0.54	GO:0060559	positive regulation of calcidiol 1-monooxygenase activity
0.54	GO:0032747	positive regulation of interleukin-23 production

0.86	GO:0005133	interferon-gamma receptor binding
0.73	GO:0005125	cytokine activity

0.67	GO:0005615	extracellular space
0.50	GO:0043204	perikaryon
0.48	GO:0009897	external side of plasma membrane
0.46	GO:0043005	neuron projection
0.37	GO:0005737	cytoplasm

sp|P01582|IL1A_MOUSE
Interleukin-1 alpha
Search

IL1A

0.82	Interleukin-1 alpha

0.86	GO:0001660	fever generation
0.83	GO:0051781	positive regulation of cell division
0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.65	GO:0002248	connective tissue replacement involved in inflammatory response wound healing
0.65	GO:0045086	positive regulation of interleukin-2 biosynthetic process
0.65	GO:2000391	positive regulation of neutrophil extravasation
0.64	GO:0046688	response to copper ion
0.64	GO:0034605	cellular response to heat
0.64	GO:0071639	positive regulation of monocyte chemotactic protein-1 production

0.86	GO:0005149	interleukin-1 receptor binding
0.80	GO:0005125	cytokine activity
0.58	GO:0005507	copper ion binding

0.73	GO:0005615	extracellular space
0.68	GO:0005829	cytosol
0.36	GO:0009986	cell surface
0.34	GO:0005886	plasma membrane

sp|P01586|IL3_MOUSE
Interleukin-3
Search

IL3

0.83	Interleukin-3

0.82	GO:0038156	interleukin-3-mediated signaling pathway
0.78	GO:0033026	negative regulation of mast cell apoptotic process
0.78	GO:0070668	positive regulation of mast cell proliferation
0.78	GO:0033028	myeloid cell apoptotic process
0.77	GO:0042976	activation of Janus kinase activity
0.76	GO:0010469	regulation of receptor activity
0.75	GO:1903131	mononuclear cell differentiation
0.74	GO:0006955	immune response
0.74	GO:0038034	signal transduction in absence of ligand
0.73	GO:0006110	regulation of glycolytic process

0.88	GO:0005135	interleukin-3 receptor binding
0.81	GO:0005125	cytokine activity
0.78	GO:0008083	growth factor activity
0.64	GO:0005149	interleukin-1 receptor binding

0.73

GO:0005615

extracellular space

sp|P01587|CSF2_MOUSE
Granulocyte-macrophage colony-stimulating factor
Search

CSF2

0.93	Granulocyte-macrophage colony-stimulating factor

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.69	GO:0045918	negative regulation of cytolysis
0.68	GO:0032747	positive regulation of interleukin-23 production
0.68	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.68	GO:0010744	positive regulation of macrophage derived foam cell differentiation
0.67	GO:0071803	positive regulation of podosome assembly
0.67	GO:0043011	myeloid dendritic cell differentiation
0.66	GO:1901099	negative regulation of signal transduction in absence of ligand
0.66	GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand

0.87	GO:0005129	granulocyte macrophage colony-stimulating factor receptor binding
0.78	GO:0008083	growth factor activity
0.65	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.46	GO:0043227	membrane-bounded organelle
0.44	GO:0043229	intracellular organelle

sp|P01590|IL2RA_MOUSE
Interleukin-2 receptor subunit alpha
Search

IL2RA

0.97	Interleukin-2 receptor subunit alpha

0.87	GO:0038110	interleukin-2-mediated signaling pathway
0.71	GO:0002664	regulation of T cell tolerance induction
0.69	GO:0046013	regulation of T cell homeostatic proliferation
0.69	GO:0006924	activation-induced cell death of T cells
0.66	GO:0042104	positive regulation of activated T cell proliferation
0.65	GO:0042130	negative regulation of T cell proliferation
0.64	GO:0050728	negative regulation of inflammatory response
0.62	GO:0007219	Notch signaling pathway
0.54	GO:0006954	inflammatory response
0.51	GO:0006955	immune response

0.87	GO:0004911	interleukin-2 receptor activity
0.87	GO:0019976	interleukin-2 binding
0.38	GO:0008144	drug binding
0.37	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0003735	structural constituent of ribosome

0.62	GO:0009897	external side of plasma membrane
0.34	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

sp|P01592|IGJ_MOUSE
Immunoglobulin J chain
Search

JCHAIN

0.97	Joining chain of multimeric IgA and IgM

0.86	GO:0060267	positive regulation of respiratory burst
0.86	GO:0003094	glomerular filtration
0.85	GO:0032461	positive regulation of protein oligomerization
0.85	GO:0019731	antibacterial humoral response
0.82	GO:0002250	adaptive immune response
0.78	GO:0045087	innate immune response

0.87	GO:0019862	IgA binding
0.86	GO:0034987	immunoglobulin receptor binding
0.85	GO:0031210	phosphatidylcholine binding
0.79	GO:0030674	protein binding, bridging
0.76	GO:0042834	peptidoglycan binding
0.74	GO:0042803	protein homodimerization activity
0.73	GO:0003697	single-stranded DNA binding

0.88	GO:0071754	IgM immunoglobulin complex, circulating
0.87	GO:0071750	dimeric IgA immunoglobulin complex
0.87	GO:0071751	secretory IgA immunoglobulin complex
0.87	GO:0071748	monomeric IgA immunoglobulin complex
0.30	GO:0016020	membrane

sp|P01627|KV2A2_MOUSE
Ig kappa chain V-II region VKappa167
Search

0.96	Ig kappa chain V-II region MOPC 167

0.71	GO:0002377	immunoglobulin production
0.68	GO:0006955	immune response
0.61	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.61	GO:0038095	Fc-epsilon receptor signaling pathway
0.59	GO:0030449	regulation of complement activation
0.57	GO:0002449	lymphocyte mediated immunity
0.57	GO:0072376	protein activation cascade
0.57	GO:0050900	leukocyte migration
0.51	GO:0006898	receptor-mediated endocytosis
0.46	GO:0006508	proteolysis

0.75	GO:0003823	antigen binding
0.50	GO:0004252	serine-type endopeptidase activity
0.35	GO:0046872	metal ion binding

0.65	GO:0005615	extracellular space
0.48	GO:1903561	extracellular vesicle
0.45	GO:0005886	plasma membrane

0.50

GO:0004252

sp|P01629|KV2A4_MOUSE
Ig kappa chain V-II region 2S1.3
Search

0.97	Immunoglobulin kappa variable 2-28

0.67	GO:0006955	immune response
0.66	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.66	GO:0002377	immunoglobulin production
0.65	GO:0038095	Fc-epsilon receptor signaling pathway
0.64	GO:0030449	regulation of complement activation
0.62	GO:0002449	lymphocyte mediated immunity
0.61	GO:0072376	protein activation cascade
0.61	GO:0050900	leukocyte migration
0.55	GO:0006898	receptor-mediated endocytosis
0.48	GO:0006508	proteolysis

0.77	GO:0003823	antigen binding
0.53	GO:0004252	serine-type endopeptidase activity
0.36	GO:0046872	metal ion binding

0.63	GO:0005615	extracellular space
0.51	GO:1903561	extracellular vesicle
0.47	GO:0005886	plasma membrane

0.53

GO:0004252

sp|P01630|KV2A6_MOUSE
Ig kappa chain V-II region 7S34.1
Search

0.92	Myosin-reactive immunoglobulin light chain variable region (Fragment)

0.78	GO:0002377	immunoglobulin production
0.70	GO:0006955	immune response
0.50	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.49	GO:0038095	Fc-epsilon receptor signaling pathway
0.48	GO:0030449	regulation of complement activation
0.47	GO:0002449	lymphocyte mediated immunity
0.47	GO:0072376	protein activation cascade
0.47	GO:0050900	leukocyte migration
0.43	GO:0006898	receptor-mediated endocytosis
0.40	GO:0006508	proteolysis

0.61	GO:0003823	antigen binding
0.42	GO:0004252	serine-type endopeptidase activity
0.36	GO:0046872	metal ion binding

0.68	GO:0005615	extracellular space
0.42	GO:1903561	extracellular vesicle
0.40	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.42

GO:0004252

sp|P01631|KV2A7_MOUSE
Ig kappa chain V-II region 26-10
Search

0.89	Myosin-reactive immunoglobulin light chain variable region (Fragment)

0.79	GO:0002377	immunoglobulin production
0.71	GO:0006955	immune response
0.51	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.50	GO:0038095	Fc-epsilon receptor signaling pathway
0.49	GO:0030449	regulation of complement activation
0.48	GO:0002449	lymphocyte mediated immunity
0.48	GO:0072376	protein activation cascade
0.48	GO:0050900	leukocyte migration
0.44	GO:0006898	receptor-mediated endocytosis
0.40	GO:0006508	proteolysis

0.57	GO:0003823	antigen binding
0.43	GO:0004252	serine-type endopeptidase activity
0.37	GO:0046872	metal ion binding

0.70	GO:0005615	extracellular space
0.42	GO:1903561	extracellular vesicle
0.41	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.43

GO:0004252

sp|P01632|KV1A1_MOUSE
Ig kappa chain V-I region S107A
Search

0.93	Anti-staphylococcal enterotoxin D variable region kappa chain (Fragment)

0.81	GO:0002377	immunoglobulin production
0.71	GO:0006955	immune response
0.43	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.42	GO:0038095	Fc-epsilon receptor signaling pathway
0.42	GO:0030449	regulation of complement activation
0.41	GO:0002449	lymphocyte mediated immunity
0.41	GO:0072376	protein activation cascade
0.41	GO:0050900	leukocyte migration
0.39	GO:0006898	receptor-mediated endocytosis
0.36	GO:0006508	proteolysis

0.55	GO:0003823	antigen binding
0.38	GO:0004252	serine-type endopeptidase activity
0.34	GO:0046872	metal ion binding
0.34	GO:0003676	nucleic acid binding

0.71	GO:0005615	extracellular space
0.43	GO:1903561	extracellular vesicle
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.38

GO:0004252

sp|P01633|KV5A1_MOUSE
Ig kappa chain V19-17
Search

0.92	Ig kappa chain V-I region

0.79	GO:0002377	immunoglobulin production
0.69	GO:0006955	immune response
0.42	GO:0002449	lymphocyte mediated immunity
0.42	GO:0002429	immune response-activating cell surface receptor signaling pathway
0.42	GO:0072376	protein activation cascade
0.42	GO:0006909	phagocytosis
0.40	GO:0038094	Fc-gamma receptor signaling pathway
0.40	GO:0038095	Fc-epsilon receptor signaling pathway
0.39	GO:0030449	regulation of complement activation
0.39	GO:0050900	leukocyte migration

0.56	GO:0003823	antigen binding
0.39	GO:0034987	immunoglobulin receptor binding
0.37	GO:0046872	metal ion binding
0.36	GO:0004252	serine-type endopeptidase activity
0.34	GO:0003676	nucleic acid binding

0.69	GO:0005615	extracellular space
0.43	GO:1903561	extracellular vesicle
0.38	GO:0019814	immunoglobulin complex
0.38	GO:0005886	plasma membrane
0.37	GO:0009986	cell surface
0.37	GO:0098552	side of membrane

0.36

GO:0004252

sp|P01634|KV5A2_MOUSE
Ig kappa chain V-V region MOPC 21
Search

0.95	B cell antigen receptor

0.78	GO:0002377	immunoglobulin production
0.68	GO:0006955	immune response
0.39	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.39	GO:0038095	Fc-epsilon receptor signaling pathway
0.38	GO:0030449	regulation of complement activation
0.38	GO:0002449	lymphocyte mediated immunity
0.38	GO:0072376	protein activation cascade
0.38	GO:0050900	leukocyte migration
0.36	GO:0006898	receptor-mediated endocytosis
0.35	GO:0006508	proteolysis

0.61	GO:0003823	antigen binding
0.36	GO:0004252	serine-type endopeptidase activity
0.35	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0032561	guanyl ribonucleotide binding
0.34	GO:0003676	nucleic acid binding
0.34	GO:0046872	metal ion binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.68	GO:0005615	extracellular space
0.41	GO:1903561	extracellular vesicle
0.37	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.36

GO:0004252

sp|P01635|KV5A3_MOUSE
Ig kappa chain V-V region K2 (Fragment)
Search

0.97	Anti-carcinoma embryonic antigen light chain variable region (Fragment)

0.78	GO:0002377	immunoglobulin production
0.74	GO:0006955	immune response
0.71	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.70	GO:0038095	Fc-epsilon receptor signaling pathway
0.68	GO:0030449	regulation of complement activation
0.66	GO:0002449	lymphocyte mediated immunity
0.65	GO:0072376	protein activation cascade
0.65	GO:0050900	leukocyte migration
0.58	GO:0006898	receptor-mediated endocytosis
0.50	GO:0006508	proteolysis

0.74	GO:0003823	antigen binding
0.56	GO:0004252	serine-type endopeptidase activity

0.72	GO:0005615	extracellular space
0.59	GO:1903561	extracellular vesicle
0.50	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.56

GO:0004252

sp|P01636|KV5A4_MOUSE
Ig kappa chain V-V region MOPC 149
Search

0.93	Anti-streptococcal/anti-myosin immunoglobulin kappa light chain variable region (Fragment)

0.78	GO:0002377	immunoglobulin production
0.74	GO:0006955	immune response
0.65	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.64	GO:0038095	Fc-epsilon receptor signaling pathway
0.63	GO:0030449	regulation of complement activation
0.61	GO:0002449	lymphocyte mediated immunity
0.60	GO:0072376	protein activation cascade
0.60	GO:0050900	leukocyte migration
0.54	GO:0006898	receptor-mediated endocytosis
0.47	GO:0006508	proteolysis

0.76	GO:0003823	antigen binding
0.52	GO:0004252	serine-type endopeptidase activity

0.70	GO:0005615	extracellular space
0.54	GO:1903561	extracellular vesicle
0.51	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.52

GO:0004252

sp|P01637|KV5A5_MOUSE
Ig kappa chain V-V region T1
Search

0.96	Immunoglobulin kappa variable 1-6

0.76	GO:0002377	immunoglobulin production
0.73	GO:0006955	immune response
0.66	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.65	GO:0038095	Fc-epsilon receptor signaling pathway
0.63	GO:0030449	regulation of complement activation
0.61	GO:0002449	lymphocyte mediated immunity
0.61	GO:0072376	protein activation cascade
0.61	GO:0050900	leukocyte migration
0.54	GO:0006898	receptor-mediated endocytosis
0.48	GO:0006508	proteolysis

0.74	GO:0003823	antigen binding
0.53	GO:0004252	serine-type endopeptidase activity
0.40	GO:0042802	identical protein binding
0.38	GO:0003964	RNA-directed DNA polymerase activity

0.70	GO:0005615	extracellular space
0.55	GO:1903561	extracellular vesicle
0.50	GO:0005886	plasma membrane

0.53

GO:0004252

sp|P01638|KV5A6_MOUSE
Ig kappa chain V-V region L6 (Fragment)
Search

0.97	Immunoglobulin kappa variable 1-8

0.74	GO:0002377	immunoglobulin production
0.74	GO:0006955	immune response
0.69	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.68	GO:0038095	Fc-epsilon receptor signaling pathway
0.66	GO:0030449	regulation of complement activation
0.64	GO:0002449	lymphocyte mediated immunity
0.63	GO:0072376	protein activation cascade
0.63	GO:0050900	leukocyte migration
0.56	GO:0006898	receptor-mediated endocytosis
0.49	GO:0006508	proteolysis

0.75	GO:0003823	antigen binding
0.54	GO:0004252	serine-type endopeptidase activity
0.39	GO:0042802	identical protein binding

0.71	GO:0005615	extracellular space
0.58	GO:1903561	extracellular vesicle
0.50	GO:0005886	plasma membrane

0.54

GO:0004252

sp|P01639|KV5A7_MOUSE
Ig kappa chain V-V region MOPC 41
Search

0.84	Immunoglobulin kappa variable 1-5

0.76	GO:0002377	immunoglobulin production
0.74	GO:0006955	immune response
0.69	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.68	GO:0038095	Fc-epsilon receptor signaling pathway
0.67	GO:0030449	regulation of complement activation
0.64	GO:0002449	lymphocyte mediated immunity
0.64	GO:0072376	protein activation cascade
0.64	GO:0050900	leukocyte migration
0.57	GO:0006898	receptor-mediated endocytosis
0.50	GO:0006508	proteolysis

0.70	GO:0003823	antigen binding
0.55	GO:0004252	serine-type endopeptidase activity
0.41	GO:0042802	identical protein binding

0.72	GO:0005615	extracellular space
0.60	GO:1903561	extracellular vesicle
0.48	GO:0005886	plasma membrane

0.55

GO:0004252

sp|P01641|KV5A8_MOUSE
Ig kappa chain V-V region MOPC 173B
Search

0.97	Immunoglobulin kappa variable 1-5

0.74	GO:0002377	immunoglobulin production
0.74	GO:0006955	immune response
0.73	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.72	GO:0038095	Fc-epsilon receptor signaling pathway
0.70	GO:0030449	regulation of complement activation
0.68	GO:0002449	lymphocyte mediated immunity
0.67	GO:0072376	protein activation cascade
0.67	GO:0050900	leukocyte migration
0.59	GO:0006898	receptor-mediated endocytosis
0.51	GO:0006508	proteolysis

0.75	GO:0003823	antigen binding
0.57	GO:0004252	serine-type endopeptidase activity
0.41	GO:0042802	identical protein binding

0.72	GO:0005615	extracellular space
0.62	GO:1903561	extracellular vesicle
0.51	GO:0005886	plasma membrane

0.57

GO:0004252

sp|P01642|KV5A9_MOUSE
Ig kappa chain V-V region L7 (Fragment)
Search

0.91	Ig kappa chain V-I region Walker

0.81	GO:0002377	immunoglobulin production
0.70	GO:0006955	immune response
0.36	GO:0006278	RNA-dependent DNA biosynthetic process

0.57	GO:0003823	antigen binding
0.36	GO:0003964	RNA-directed DNA polymerase activity

0.69	GO:0005615	extracellular space
0.37	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:2.7.7.49

GO:0003964

sp|P01643|KV5AA_MOUSE
Ig kappa chain V-V region MOPC 173
Search

0.89	Anti-streptococcal/anti-myosin immunoglobulin kappa light chain variable region (Fragment)

0.76	GO:0002377	immunoglobulin production
0.74	GO:0006955	immune response
0.65	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.64	GO:0038095	Fc-epsilon receptor signaling pathway
0.63	GO:0030449	regulation of complement activation
0.61	GO:0002449	lymphocyte mediated immunity
0.60	GO:0072376	protein activation cascade
0.60	GO:0050900	leukocyte migration
0.54	GO:0006898	receptor-mediated endocytosis
0.47	GO:0006508	proteolysis

0.77	GO:0003823	antigen binding
0.52	GO:0004252	serine-type endopeptidase activity
0.39	GO:0042802	identical protein binding

0.71	GO:0005615	extracellular space
0.57	GO:1903561	extracellular vesicle
0.51	GO:0005886	plasma membrane

0.52

GO:0004252

sp|P01644|KV5AB_MOUSE
Ig kappa chain V-V region HP R16.7
Search

0.90	Anti-streptococcal/anti-myosin immunoglobulin kappa light chain variable region (Fragment)

0.78	GO:0002377	immunoglobulin production
0.74	GO:0006955	immune response
0.67	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.66	GO:0038095	Fc-epsilon receptor signaling pathway
0.64	GO:0030449	regulation of complement activation
0.62	GO:0002449	lymphocyte mediated immunity
0.62	GO:0072376	protein activation cascade
0.61	GO:0050900	leukocyte migration
0.55	GO:0006898	receptor-mediated endocytosis
0.48	GO:0006508	proteolysis

0.76	GO:0003823	antigen binding
0.53	GO:0004252	serine-type endopeptidase activity
0.40	GO:0042802	identical protein binding

0.72	GO:0005615	extracellular space
0.58	GO:1903561	extracellular vesicle
0.51	GO:0005886	plasma membrane

0.53

GO:0004252

sp|P01645|KV5AC_MOUSE
Ig kappa chain V-V region HP 93G7
Search

0.90	Anti-streptococcal/anti-myosin immunoglobulin kappa light chain variable region (Fragment)

0.78	GO:0002377	immunoglobulin production
0.74	GO:0006955	immune response
0.67	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.66	GO:0038095	Fc-epsilon receptor signaling pathway
0.64	GO:0030449	regulation of complement activation
0.62	GO:0002449	lymphocyte mediated immunity
0.62	GO:0072376	protein activation cascade
0.61	GO:0050900	leukocyte migration
0.55	GO:0006898	receptor-mediated endocytosis
0.48	GO:0006508	proteolysis

0.76	GO:0003823	antigen binding
0.53	GO:0004252	serine-type endopeptidase activity
0.40	GO:0042802	identical protein binding

0.72	GO:0005615	extracellular space
0.58	GO:1903561	extracellular vesicle
0.51	GO:0005886	plasma membrane

0.53

GO:0004252

sp|P01646|KV5AD_MOUSE
Ig kappa chain V-V region HP 123E6
Search

0.90	Anti-streptococcal/anti-myosin immunoglobulin kappa light chain variable region (Fragment)

0.74	GO:0002377	immunoglobulin production
0.74	GO:0006955	immune response
0.74	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.73	GO:0038095	Fc-epsilon receptor signaling pathway
0.71	GO:0030449	regulation of complement activation
0.68	GO:0002449	lymphocyte mediated immunity
0.68	GO:0072376	protein activation cascade
0.67	GO:0050900	leukocyte migration
0.60	GO:0006898	receptor-mediated endocytosis
0.52	GO:0006508	proteolysis

0.76	GO:0003823	antigen binding
0.57	GO:0004252	serine-type endopeptidase activity
0.41	GO:0042802	identical protein binding

0.72	GO:0005615	extracellular space
0.64	GO:1903561	extracellular vesicle
0.51	GO:0005886	plasma membrane

0.57

GO:0004252

sp|P01647|KV5AE_MOUSE
Ig kappa chain V-V region HP 124E1
Search

0.88	Anti-streptococcal/anti-myosin immunoglobulin kappa light chain variable region (Fragment)

0.79	GO:0002377	immunoglobulin production
0.74	GO:0006955	immune response
0.66	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.65	GO:0038095	Fc-epsilon receptor signaling pathway
0.63	GO:0030449	regulation of complement activation
0.61	GO:0002449	lymphocyte mediated immunity
0.61	GO:0072376	protein activation cascade
0.61	GO:0050900	leukocyte migration
0.54	GO:0006898	receptor-mediated endocytosis
0.48	GO:0006508	proteolysis

0.75	GO:0003823	antigen binding
0.53	GO:0004252	serine-type endopeptidase activity
0.39	GO:0042802	identical protein binding

0.72	GO:0005615	extracellular space
0.58	GO:1903561	extracellular vesicle
0.50	GO:0005886	plasma membrane

0.53

GO:0004252

sp|P01648|KV5AF_MOUSE
Ig kappa chain V-V region HP 91A3
Search

0.86	Anti-streptococcal/anti-myosin immunoglobulin kappa light chain variable region (Fragment)

0.80	GO:0002377	immunoglobulin production
0.74	GO:0006955	immune response
0.68	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.67	GO:0038095	Fc-epsilon receptor signaling pathway
0.66	GO:0030449	regulation of complement activation
0.63	GO:0002449	lymphocyte mediated immunity
0.63	GO:0072376	protein activation cascade
0.63	GO:0050900	leukocyte migration
0.56	GO:0006898	receptor-mediated endocytosis
0.49	GO:0006508	proteolysis

0.75	GO:0003823	antigen binding
0.54	GO:0004252	serine-type endopeptidase activity

0.72	GO:0005615	extracellular space
0.57	GO:1903561	extracellular vesicle
0.50	GO:0005886	plasma membrane

0.54

GO:0004252

sp|P01649|KV5AG_MOUSE
Ig kappa chain V-V regions
Search

0.84	Ig kappa chain V-V regions

0.85

GO:0003823

antigen binding

sp|P01650|KV5AH_MOUSE
Ig kappa chain V-V region UPC 61
Search

0.92	Anti-streptococcal/anti-myosin immunoglobulin kappa light chain variable region (Fragment)

0.80	GO:0002250	adaptive immune response
0.76	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.75	GO:0038095	Fc-epsilon receptor signaling pathway
0.73	GO:0030449	regulation of complement activation
0.71	GO:0002449	lymphocyte mediated immunity
0.70	GO:0006956	complement activation
0.70	GO:0050900	leukocyte migration
0.68	GO:0002377	immunoglobulin production
0.61	GO:0006898	receptor-mediated endocytosis
0.53	GO:0006508	proteolysis

0.83	GO:0003823	antigen binding
0.59	GO:0004252	serine-type endopeptidase activity
0.42	GO:0042802	identical protein binding

0.69	GO:0005615	extracellular space
0.63	GO:1903561	extracellular vesicle
0.54	GO:0005886	plasma membrane

0.59

GO:0004252

sp|P01652|KV5AK_MOUSE
Ig kappa chain V-V region J606
Search

0.93	Anti-streptococcal/anti-myosin immunoglobulin kappa light chain variable region (Fragment)

0.76	GO:0002377	immunoglobulin production
0.70	GO:0006955	immune response
0.55	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.54	GO:0038095	Fc-epsilon receptor signaling pathway
0.53	GO:0030449	regulation of complement activation
0.51	GO:0002449	lymphocyte mediated immunity
0.51	GO:0072376	protein activation cascade
0.51	GO:0050900	leukocyte migration
0.47	GO:0006898	receptor-mediated endocytosis
0.42	GO:0006508	proteolysis

0.67	GO:0003823	antigen binding
0.46	GO:0004252	serine-type endopeptidase activity
0.37	GO:0042802	identical protein binding
0.33	GO:0003676	nucleic acid binding

0.68	GO:0005615	extracellular space
0.48	GO:1903561	extracellular vesicle
0.43	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.46

GO:0004252

sp|P01653|KV5AL_MOUSE
Ig kappa chain V-V region W3082
Search

0.92	Anti-streptococcal/anti-myosin immunoglobulin kappa light chain variable region (Fragment)

0.80	GO:0002250	adaptive immune response
0.76	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.75	GO:0038095	Fc-epsilon receptor signaling pathway
0.73	GO:0030449	regulation of complement activation
0.71	GO:0002449	lymphocyte mediated immunity
0.70	GO:0006956	complement activation
0.70	GO:0050900	leukocyte migration
0.68	GO:0002377	immunoglobulin production
0.61	GO:0006898	receptor-mediated endocytosis
0.53	GO:0006508	proteolysis

0.83	GO:0003823	antigen binding
0.59	GO:0004252	serine-type endopeptidase activity
0.42	GO:0042802	identical protein binding

0.69	GO:0005615	extracellular space
0.63	GO:1903561	extracellular vesicle
0.54	GO:0005886	plasma membrane

0.59

GO:0004252

sp|P01654|KV3A1_MOUSE
Ig kappa chain V-III region PC 2880/PC 1229
Search

0.94	Ig kappa chain V-V regions

0.67	GO:0002377	immunoglobulin production
0.59	GO:0006955	immune response
0.37	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.37	GO:0038095	Fc-epsilon receptor signaling pathway
0.37	GO:0030449	regulation of complement activation
0.36	GO:0002449	lymphocyte mediated immunity
0.36	GO:0072376	protein activation cascade
0.36	GO:0050900	leukocyte migration
0.35	GO:0006898	receptor-mediated endocytosis
0.34	GO:0006508	proteolysis

0.72	GO:0003823	antigen binding
0.35	GO:0004252	serine-type endopeptidase activity

0.59	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.33	GO:0005886	plasma membrane

0.35

GO:0004252

sp|P01655|KV3A2_MOUSE
Ig kappa chain V-III region PC 7132
Search

0.94	Ig kappa chain V-V regions

0.67	GO:0002377	immunoglobulin production
0.59	GO:0006955	immune response
0.37	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.37	GO:0038095	Fc-epsilon receptor signaling pathway
0.37	GO:0030449	regulation of complement activation
0.36	GO:0002449	lymphocyte mediated immunity
0.36	GO:0072376	protein activation cascade
0.36	GO:0050900	leukocyte migration
0.35	GO:0006898	receptor-mediated endocytosis
0.34	GO:0006508	proteolysis

0.73	GO:0003823	antigen binding
0.35	GO:0004252	serine-type endopeptidase activity

0.58	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.33	GO:0005886	plasma membrane

0.35

GO:0004252

sp|P01656|KV3A3_MOUSE
Ig kappa chain V-III region MOPC 70
Search

0.93	Ig kappa chain V-V regions

0.67	GO:0002377	immunoglobulin production
0.59	GO:0006955	immune response
0.37	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.37	GO:0038095	Fc-epsilon receptor signaling pathway
0.37	GO:0030449	regulation of complement activation
0.36	GO:0002449	lymphocyte mediated immunity
0.36	GO:0072376	protein activation cascade
0.36	GO:0050900	leukocyte migration
0.35	GO:0006898	receptor-mediated endocytosis
0.34	GO:0006508	proteolysis

0.72	GO:0003823	antigen binding
0.35	GO:0004252	serine-type endopeptidase activity

0.59	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.33	GO:0005886	plasma membrane

0.35

GO:0004252

sp|P01657|KV3A5_MOUSE
Ig kappa chain V-III region PC 2413
Search

0.92	Ig kappa chain V-III region HIC

0.68	GO:0002377	immunoglobulin production
0.60	GO:0006955	immune response
0.37	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.37	GO:0038095	Fc-epsilon receptor signaling pathway
0.37	GO:0030449	regulation of complement activation
0.36	GO:0002449	lymphocyte mediated immunity
0.36	GO:0072376	protein activation cascade
0.36	GO:0050900	leukocyte migration
0.35	GO:0006898	receptor-mediated endocytosis
0.34	GO:0006508	proteolysis

0.72	GO:0003823	antigen binding
0.35	GO:0004252	serine-type endopeptidase activity

0.60	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.33	GO:0005886	plasma membrane

0.35

GO:0004252

sp|P01658|KV3A6_MOUSE
Ig kappa chain V-III region MOPC 321
Search

0.91	Ig kappa chain V-III region VG

0.69	GO:0002377	immunoglobulin production
0.62	GO:0006955	immune response
0.38	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.38	GO:0003094	glomerular filtration
0.38	GO:0038095	Fc-epsilon receptor signaling pathway
0.37	GO:0030449	regulation of complement activation
0.37	GO:0002449	lymphocyte mediated immunity
0.37	GO:0072376	protein activation cascade
0.37	GO:0050900	leukocyte migration
0.36	GO:0042742	defense response to bacterium

0.69	GO:0003823	antigen binding
0.35	GO:0004252	serine-type endopeptidase activity

0.61	GO:0005615	extracellular space
0.38	GO:0071745	IgA immunoglobulin complex
0.38	GO:0071753	IgM immunoglobulin complex
0.37	GO:1903561	extracellular vesicle
0.33	GO:0005886	plasma membrane

0.35

GO:0004252

sp|P01659|KV3A7_MOUSE
Ig kappa chain V-III region TEPC 124
Search

0.91	Ig kappa chain V-III region HIC

0.66	GO:0002377	immunoglobulin production
0.59	GO:0006955	immune response
0.38	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.38	GO:0038095	Fc-epsilon receptor signaling pathway
0.38	GO:0003094	glomerular filtration
0.37	GO:0030449	regulation of complement activation
0.37	GO:0002449	lymphocyte mediated immunity
0.37	GO:0072376	protein activation cascade
0.37	GO:0050900	leukocyte migration
0.36	GO:0042742	defense response to bacterium

0.72	GO:0003823	antigen binding
0.35	GO:0004252	serine-type endopeptidase activity

0.59	GO:0005615	extracellular space
0.38	GO:0071745	IgA immunoglobulin complex
0.38	GO:0071753	IgM immunoglobulin complex
0.36	GO:1903561	extracellular vesicle
0.33	GO:0005886	plasma membrane

0.35

GO:0004252

sp|P01660|KV3A8_MOUSE
Ig kappa chain V-III region PC 3741/TEPC 111
Search

0.93	Ig kappa chain V-V regions

0.66	GO:0002377	immunoglobulin production
0.58	GO:0006955	immune response
0.38	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.38	GO:0038095	Fc-epsilon receptor signaling pathway
0.37	GO:0030449	regulation of complement activation
0.37	GO:0002449	lymphocyte mediated immunity
0.37	GO:0072376	protein activation cascade
0.37	GO:0050900	leukocyte migration
0.35	GO:0006898	receptor-mediated endocytosis
0.34	GO:0006508	proteolysis

0.73	GO:0003823	antigen binding
0.35	GO:0004252	serine-type endopeptidase activity

0.58	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.33	GO:0005886	plasma membrane

0.35

GO:0004252

sp|P01661|KV3A9_MOUSE
Ig kappa chain V-III region MOPC 63
Search

0.92	Ig kappa chain V-III region HIC

0.66	GO:0002377	immunoglobulin production
0.59	GO:0006955	immune response

0.73

GO:0003823

antigen binding

0.58

GO:0005615

extracellular space

sp|P01662|KV3AA_MOUSE
Ig kappa chain V-III region ABPC 22/PC 9245
Search

0.93	Ig kappa chain V-III region HIC

0.65	GO:0002377	immunoglobulin production
0.58	GO:0006955	immune response

0.73

GO:0003823

antigen binding

0.57

GO:0005615

extracellular space

sp|P01663|KV3AB_MOUSE
Ig kappa chain V-III region PC 4050
Search

0.93	Ig kappa chain V-III region HIC

0.65	GO:0002377	immunoglobulin production
0.57	GO:0006955	immune response

0.74

GO:0003823

antigen binding

0.57

GO:0005615

extracellular space

sp|P01664|KV3AC_MOUSE
Ig kappa chain V-III region CBPC 101
Search

0.94	Ig kappa chain V-III region MOPC 63

0.70	GO:0002377	immunoglobulin production
0.62	GO:0006955	immune response

0.69	GO:0003823	antigen binding
0.35	GO:0046872	metal ion binding

0.61	GO:0005615	extracellular space
0.35	GO:0005886	plasma membrane

sp|P01665|KV3AD_MOUSE
Ig kappa chain V-III region PC 7043
Search

0.93	Ig kappa chain V-V regions

0.64	GO:0002377	immunoglobulin production
0.57	GO:0006955	immune response

0.75

GO:0003823

antigen binding

0.57	GO:0005615	extracellular space
0.35	GO:0005886	plasma membrane

sp|P01666|KV3AE_MOUSE
Ig kappa chain V-III region PC 7183
Search

0.93	Ig kappa chain V-V regions

0.64	GO:0002377	immunoglobulin production
0.57	GO:0006955	immune response

0.75

GO:0003823

antigen binding

0.56	GO:0005615	extracellular space
0.34	GO:0005886	plasma membrane

sp|P01667|KV3AF_MOUSE
Ig kappa chain V-III region PC 6308
Search

0.92	Ig kappa chain V-V regions

0.66	GO:0002377	immunoglobulin production
0.58	GO:0006955	immune response
0.38	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.38	GO:0038095	Fc-epsilon receptor signaling pathway
0.37	GO:0030449	regulation of complement activation
0.37	GO:0002449	lymphocyte mediated immunity
0.37	GO:0072376	protein activation cascade
0.37	GO:0050900	leukocyte migration
0.36	GO:0006898	receptor-mediated endocytosis
0.34	GO:0006508	proteolysis

0.74	GO:0003823	antigen binding
0.35	GO:0004252	serine-type endopeptidase activity

0.58	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.35	GO:0005886	plasma membrane

0.35

GO:0004252

sp|P01668|KV3AG_MOUSE
Ig kappa chain V-III region PC 7210
Search

0.93	Ig kappa chain V-V regions

0.69	GO:0002377	immunoglobulin production
0.61	GO:0006955	immune response
0.38	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.38	GO:0038095	Fc-epsilon receptor signaling pathway
0.37	GO:0030449	regulation of complement activation
0.37	GO:0002449	lymphocyte mediated immunity
0.37	GO:0072376	protein activation cascade
0.37	GO:0050900	leukocyte migration
0.35	GO:0006898	receptor-mediated endocytosis
0.34	GO:0006508	proteolysis

0.72	GO:0003823	antigen binding
0.35	GO:0004252	serine-type endopeptidase activity

0.60	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:0005886	plasma membrane

0.35

GO:0004252

sp|P01669|KV3AH_MOUSE
Ig kappa chain V-III region PC 7769
Search

0.92	Ig kappa chain V-V regions

0.70	GO:0002377	immunoglobulin production
0.61	GO:0006955	immune response

0.70

GO:0003823

antigen binding

0.61	GO:0005615	extracellular space
0.33	GO:0005886	plasma membrane

sp|P01670|KV3AI_MOUSE
Ig kappa chain V-III region PC 6684
Search

0.94	Ig kappa chain V-V regions

0.65	GO:0002377	immunoglobulin production
0.57	GO:0006955	immune response

0.73	GO:0003823	antigen binding
0.34	GO:0046872	metal ion binding

0.57	GO:0005615	extracellular space
0.33	GO:0005886	plasma membrane

sp|P01671|KV3AJ_MOUSE
Ig kappa chain V-III region PC 7175
Search

0.93	Ig kappa chain V-V regions

0.65	GO:0002377	immunoglobulin production
0.58	GO:0006955	immune response

0.74

GO:0003823

antigen binding

0.57	GO:0005615	extracellular space
0.33	GO:0005886	plasma membrane

sp|P01672|KV3AK_MOUSE
Ig kappa chain V-III region PC 7940
Search

0.93	Ig kappa chain V-V regions

0.64	GO:0002377	immunoglobulin production
0.57	GO:0006955	immune response
0.38	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.38	GO:0038095	Fc-epsilon receptor signaling pathway
0.37	GO:0030449	regulation of complement activation
0.37	GO:0002449	lymphocyte mediated immunity
0.37	GO:0072376	protein activation cascade
0.37	GO:0050900	leukocyte migration
0.35	GO:0006898	receptor-mediated endocytosis
0.34	GO:0006508	proteolysis

0.75	GO:0003823	antigen binding
0.35	GO:0004252	serine-type endopeptidase activity
0.33	GO:0046872	metal ion binding

0.56	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.33	GO:0005886	plasma membrane

0.35

GO:0004252

sp|P01673|KV3AL_MOUSE
Ig kappa chain V-III region PC 2485/PC 4039
Search

0.93	Ig kappa chain V-V regions

0.64	GO:0002377	immunoglobulin production
0.57	GO:0006955	immune response
0.38	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.38	GO:0038095	Fc-epsilon receptor signaling pathway
0.37	GO:0030449	regulation of complement activation
0.37	GO:0002449	lymphocyte mediated immunity
0.37	GO:0072376	protein activation cascade
0.37	GO:0050900	leukocyte migration
0.36	GO:0006898	receptor-mediated endocytosis
0.34	GO:0006508	proteolysis

0.75	GO:0003823	antigen binding
0.35	GO:0004252	serine-type endopeptidase activity

0.57	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.34	GO:0005886	plasma membrane

0.35

GO:0004252

sp|P01674|KV3AM_MOUSE
Ig kappa chain V-III region PC 2154
Search

0.93	Ig kappa chain V-V regions

0.68	GO:0002377	immunoglobulin production
0.60	GO:0006955	immune response
0.38	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.37	GO:0038095	Fc-epsilon receptor signaling pathway
0.37	GO:0030449	regulation of complement activation
0.37	GO:0002449	lymphocyte mediated immunity
0.37	GO:0072376	protein activation cascade
0.36	GO:0050900	leukocyte migration
0.35	GO:0006898	receptor-mediated endocytosis
0.34	GO:0006508	proteolysis

0.72	GO:0003823	antigen binding
0.35	GO:0004252	serine-type endopeptidase activity

0.60	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:0005886	plasma membrane

0.35

GO:0004252

sp|P01675|KV6A1_MOUSE
Ig kappa chain V-VI region XRPC 44
Search

0.93	Pterin-mimicking anti-idiotope kappa chain variable region (Fragment)

0.85	GO:0002377	immunoglobulin production
0.73	GO:0006955	immune response

0.73

GO:0005615

extracellular space

sp|P01676|KV6A2_MOUSE
Ig kappa chain V-VI region XRPC 24
Search

0.92	Pterin-mimicking anti-idiotope kappa chain variable region (Fragment)

0.85	GO:0002377	immunoglobulin production
0.73	GO:0006955	immune response

0.73

GO:0005615

extracellular space

sp|P01677|KV6A3_MOUSE
Ig kappa chain V-VI region TEPC 601/TEPC 191
Search

0.92	Pterin-mimicking anti-idiotope kappa chain variable region (Fragment)

0.84	GO:0002377	immunoglobulin production
0.73	GO:0006955	immune response
0.36	GO:0006278	RNA-dependent DNA biosynthetic process

0.37

GO:0003964

RNA-directed DNA polymerase activity

0.72

GO:0005615

extracellular space

0.37

EC:2.7.7.49

GO:0003964

sp|P01678|KV6A4_MOUSE
Ig kappa chain V-VI region SAPC 10
Search

0.92	Pterin-mimicking anti-idiotope kappa chain variable region (Fragment)

0.85	GO:0002377	immunoglobulin production
0.73	GO:0006955	immune response

0.73

GO:0005615

extracellular space

sp|P01679|KV6A5_MOUSE
Ig kappa chain V-VI region J539
Search

0.92	Pterin-mimicking anti-idiotope kappa chain variable region (Fragment)

0.84	GO:0002377	immunoglobulin production
0.73	GO:0006955	immune response
0.37	GO:0006278	RNA-dependent DNA biosynthetic process

0.37

GO:0003964

RNA-directed DNA polymerase activity

0.72	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.37

EC:2.7.7.49

GO:0003964

sp|P01680|KV4A1_MOUSE
Ig kappa chain V-IV region S107B
Search

0.92	Pterin-mimicking anti-idiotope kappa chain variable region (Fragment)

0.85	GO:0002377	immunoglobulin production
0.73	GO:0006955	immune response

0.73	GO:0005615	extracellular space
0.30	GO:0016020	membrane

sp|P01723|LV1A_MOUSE
Ig lambda-1 chain V region
Search

0.76	Immunoglobulin lambda variable 2

0.83	GO:0002377	immunoglobulin production
0.73	GO:0006955	immune response
0.45	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.45	GO:0038095	Fc-epsilon receptor signaling pathway
0.44	GO:0030449	regulation of complement activation
0.43	GO:0002449	lymphocyte mediated immunity
0.43	GO:0072376	protein activation cascade
0.43	GO:0050900	leukocyte migration
0.40	GO:0006898	receptor-mediated endocytosis
0.38	GO:0006508	proteolysis

0.54	GO:0003823	antigen binding
0.40	GO:0004252	serine-type endopeptidase activity

0.71	GO:0005615	extracellular space
0.41	GO:0005886	plasma membrane

0.40

GO:0004252

sp|P01724|LV1B_MOUSE
Ig lambda-1 chain V regions MOPC 104E/RPC20/J558/S104
Search

0.78	Ig lambda-1 chain V region

0.50	GO:0002377	immunoglobulin production
0.46	GO:0006955	immune response

0.85

GO:0003823

antigen binding

0.45	GO:0005615	extracellular space
0.40	GO:0005886	plasma membrane

sp|P01725|LV1C_MOUSE
Ig lambda-1 chain V region S178
Search

0.78	Ig lambda-1 chain V region

0.46	GO:0002377	immunoglobulin production
0.43	GO:0006955	immune response

0.85

GO:0003823

antigen binding

0.43	GO:0005615	extracellular space
0.38	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P01726|LV1D_MOUSE
Ig lambda-1 chain V region H2020
Search

0.77	Immunoglobulin lambda variable 2

0.85	GO:0002377	immunoglobulin production
0.74	GO:0006955	immune response

0.67

GO:0003823

antigen binding

0.73	GO:0005615	extracellular space
0.47	GO:0005886	plasma membrane

sp|P01727|LV1E_MOUSE
Ig lambda-1 chain V region S43
Search

0.81	Immunoglobulin lambda variable 2

0.83	GO:0002377	immunoglobulin production
0.73	GO:0006955	immune response
0.46	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.46	GO:0038095	Fc-epsilon receptor signaling pathway
0.45	GO:0030449	regulation of complement activation
0.44	GO:0002449	lymphocyte mediated immunity
0.44	GO:0072376	protein activation cascade
0.44	GO:0050900	leukocyte migration
0.41	GO:0006898	receptor-mediated endocytosis
0.38	GO:0006508	proteolysis

0.50	GO:0003823	antigen binding
0.40	GO:0004252	serine-type endopeptidase activity

0.71	GO:0005615	extracellular space
0.39	GO:0005886	plasma membrane

0.40