Queries 18001 to 18556

GO:0004553

tr|R4GGR3|R4GGR3_CHICK
Uncharacterized protein
Search

EFCAB2

0.97	EF-hand calcium-binding domain-containing protein 2

0.39	GO:0006468	protein phosphorylation
0.33	GO:0009738	abscisic acid-activated signaling pathway
0.33	GO:0018209	peptidyl-serine modification
0.32	GO:0035556	intracellular signal transduction
0.31	GO:0055085	transmembrane transport

0.70	GO:0005509	calcium ion binding
0.39	GO:0004672	protein kinase activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0008897	holo-[acyl-carrier-protein] synthase activity
0.35	GO:0000287	magnesium ion binding
0.32	GO:0005516	calmodulin binding
0.31	GO:0022857	transmembrane transporter activity

0.32	GO:0005634	nucleus
0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.36

EC:2.7.8.7

GO:0008897

tr|R4GGR6|R4GGR6_CHICK
Uncharacterized protein
Search

ARL4A

0.97	ADP ribosylation factor like GTPase 4A

0.52	GO:0050873	brown fat cell differentiation
0.37	GO:0032456	endocytic recycling
0.33	GO:0016579	protein deubiquitination
0.33	GO:0006511	ubiquitin-dependent protein catabolic process

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0043014	alpha-tubulin binding
0.33	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.33	GO:0003924	GTPase activity
0.32	GO:0003676	nucleic acid binding

0.48	GO:0005730	nucleolus
0.47	GO:0005829	cytosol
0.47	GO:0005654	nucleoplasm
0.42	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

EC:3.4.19.12

GO:0036459

tr|R4GGS3|R4GGS3_CHICK
Uncharacterized protein
Search

HINT2

0.53	Histidine triad nucleotide binding protein 2

0.54	GO:0044240	multicellular organismal lipid catabolic process
0.52	GO:2000757	negative regulation of peptidyl-lysine acetylation
0.39	GO:0031163	metallo-sulfur cluster assembly
0.37	GO:0006790	sulfur compound metabolic process
0.37	GO:0051188	cofactor biosynthetic process
0.36	GO:0006915	apoptotic process
0.36	GO:0006694	steroid biosynthetic process
0.34	GO:0016310	phosphorylation
0.33	GO:0051056	regulation of small GTPase mediated signal transduction
0.33	GO:0036211	protein modification process

0.39	GO:0008199	ferric iron binding
0.35	GO:0016301	kinase activity
0.34	GO:1901265	nucleoside phosphate binding
0.33	GO:0036094	small molecule binding
0.33	GO:0004146	dihydrofolate reductase activity
0.33	GO:0008252	nucleotidase activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0005096	GTPase activator activity
0.33	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0097367	carbohydrate derivative binding

0.47	GO:0005730	nucleolus
0.42	GO:0005739	mitochondrion
0.38	GO:0009507	chloroplast
0.30	GO:0016020	membrane

0.33

EC:1.5.1.3

GO:0004146

tr|R4GGS4|R4GGS4_CHICK
Uncharacterized protein
Search

tr|R4GGS6|R4GGS6_CHICK
Uncharacterized protein
Search

TMEM269

0.45	CDP-diacylglycerol--serine O-phosphatidyltransferase

0.65	GO:0008654	phospholipid biosynthetic process
0.44	GO:0045017	glycerolipid biosynthetic process
0.43	GO:0006650	glycerophospholipid metabolic process

0.68

GO:0016780

phosphotransferase activity, for other substituted phosphate groups

0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.68

EC:2.7.8

GO:0016780

tr|R4GGT1|R4GGT1_CHICK
Uncharacterized protein
Search

MESP2

0.70	Mesoderm posterior bHLH transcription factor 2

0.62	GO:0001756	somitogenesis
0.59	GO:0007498	mesoderm development
0.58	GO:0007369	gastrulation
0.57	GO:0009880	embryonic pattern specification
0.57	GO:0006366	transcription by RNA polymerase II
0.57	GO:0045944	positive regulation of transcription by RNA polymerase II
0.56	GO:0048729	tissue morphogenesis
0.55	GO:0003007	heart morphogenesis
0.52	GO:0007379	segment specification
0.49	GO:0003235	sinus venosus development

0.68	GO:0046983	protein dimerization activity
0.60	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0003682	chromatin binding
0.46	GO:0035326	enhancer binding
0.34	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.32	GO:0004519	endonuclease activity
0.32	GO:0008237	metallopeptidase activity

0.47	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome

tr|R4GGT6|R4GGT6_CHICK
Uncharacterized protein
Search

0.83	Receptor-type tyrosine-protein phosphatase mu

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.38	GO:0098902	regulation of membrane depolarization during action potential
0.38	GO:0051045	negative regulation of membrane protein ectodomain proteolysis
0.37	GO:2000649	regulation of sodium ion transmembrane transporter activity
0.37	GO:0050860	negative regulation of T cell receptor signaling pathway
0.37	GO:0051894	positive regulation of focal adhesion assembly
0.37	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.37	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.37	GO:0051898	negative regulation of protein kinase B signaling
0.36	GO:0043407	negative regulation of MAP kinase activity

0.75	GO:0004725	protein tyrosine phosphatase activity
0.66	GO:0019198	transmembrane receptor protein phosphatase activity
0.38	GO:0008092	cytoskeletal protein binding
0.37	GO:0017080	sodium channel regulator activity
0.37	GO:0001784	phosphotyrosine residue binding
0.37	GO:0051117	ATPase binding
0.37	GO:0070097	delta-catenin binding
0.36	GO:0045295	gamma-catenin binding
0.36	GO:0005161	platelet-derived growth factor receptor binding
0.36	GO:0051019	mitogen-activated protein kinase binding

0.38	GO:0005856	cytoskeleton
0.36	GO:0001772	immunological synapse
0.36	GO:0009898	cytoplasmic side of plasma membrane
0.36	GO:0005911	cell-cell junction
0.35	GO:0009986	cell surface
0.35	GO:0005737	cytoplasm
0.34	GO:0032587	ruffle membrane
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0070013	intracellular organelle lumen
0.32	GO:0019866	organelle inner membrane

0.75

EC:3.1.3.48

GO:0004725

tr|R4GGT7|R4GGT7_CHICK
Uncharacterized protein
Search

CLK1

0.88	dual specificity protein kinase CLK1

0.62	GO:0006468	protein phosphorylation
0.41	GO:0043484	regulation of RNA splicing
0.40	GO:0018212	peptidyl-tyrosine modification
0.39	GO:0018210	peptidyl-threonine modification
0.39	GO:0018209	peptidyl-serine modification
0.35	GO:0008283	cell proliferation
0.34	GO:0000413	protein peptidyl-prolyl isomerization
0.34	GO:0006457	protein folding

0.64	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0004713	protein tyrosine kinase activity
0.40	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.36	GO:0005515	protein binding
0.34	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.37	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm

0.64

GO:0004674

tr|R4GGU1|R4GGU1_CHICK
Uncharacterized protein
Search

0.40	Protein tyrosine phosphatase, non-receptor type 18 (Fragment)

tr|R4GGU2|R4GGU2_CHICK
Keratin
Search

0.84	Feather beta keratin

0.71

GO:0007010

cytoskeleton organization

0.77

GO:0005200

structural constituent of cytoskeleton

0.79

GO:0005882

intermediate filament

tr|R4GGU3|R4GGU3_CHICK
Uncharacterized protein
Search

0.83	Alpha-1-antiproteinase F

0.44	GO:0010951	negative regulation of endopeptidase activity
0.37	GO:0006508	proteolysis
0.37	GO:0007283	spermatogenesis
0.37	GO:0046628	positive regulation of insulin receptor signaling pathway
0.37	GO:0090181	regulation of cholesterol metabolic process
0.37	GO:0090207	regulation of triglyceride metabolic process
0.36	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.36	GO:0045721	negative regulation of gluconeogenesis
0.36	GO:0051055	negative regulation of lipid biosynthetic process
0.36	GO:0043434	response to peptide hormone

0.45	GO:0004867	serine-type endopeptidase inhibitor activity
0.39	GO:0032190	acrosin binding
0.38	GO:0001972	retinoic acid binding
0.38	GO:0031210	phosphatidylcholine binding
0.38	GO:0002020	protease binding
0.37	GO:0008233	peptidase activity
0.34	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.32	GO:0003677	DNA binding

0.73	GO:0005615	extracellular space
0.39	GO:0097182	protein C inhibitor-coagulation factor Xa complex
0.39	GO:0097183	protein C inhibitor-coagulation factor XI complex
0.39	GO:0097181	protein C inhibitor-coagulation factor V complex
0.39	GO:0036030	protein C inhibitor-plasma kallikrein complex
0.39	GO:0036028	protein C inhibitor-thrombin complex
0.39	GO:0036029	protein C inhibitor-KLK3 complex
0.39	GO:0036024	protein C inhibitor-TMPRSS7 complex
0.39	GO:0036026	protein C inhibitor-PLAT complex
0.39	GO:0036027	protein C inhibitor-PLAU complex

0.37

GO:0008233

tr|R4GGU8|R4GGU8_CHICK
Uncharacterized protein
Search

IGSF6

0.81	Immunoglobulin superfamily member 6

0.30

GO:0044425

membrane part

tr|R4GGV6|R4GGV6_CHICK
Uncharacterized protein
Search

tr|R4GGW5|R4GGW5_CHICK
Phospholipase A2
Search

0.66	Phospholipase A2

0.79	GO:0009395	phospholipid catabolic process
0.35	GO:0036150	phosphatidylserine acyl-chain remodeling
0.35	GO:0036152	phosphatidylethanolamine acyl-chain remodeling
0.35	GO:0036149	phosphatidylinositol acyl-chain remodeling
0.35	GO:0036151	phosphatidylcholine acyl-chain remodeling

0.82	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.82	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.79	GO:0004623	phospholipase A2 activity
0.52	GO:0046872	metal ion binding
0.34	GO:0008970	phosphatidylcholine 1-acylhydrolase activity
0.34	GO:0004622	lysophospholipase activity

0.48	GO:0005737	cytoplasm
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.32	GO:0044446	intracellular organelle part
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.79

GO:0004623

tr|R4GGW6|R4GGW6_CHICK
Uncharacterized protein
Search

KLHL33

0.97	Kelch like family member 33

0.72

GO:0016567

protein ubiquitination

0.73	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0003723	RNA binding

0.82

GO:0031463

Cul3-RING ubiquitin ligase complex

0.73

GO:0004842

tr|R4GGW7|R4GGW7_CHICK
Uncharacterized protein
Search

0.12	synaptotagmin-like protein 5

0.69	GO:0006886	intracellular protein transport
0.48	GO:0006887	exocytosis
0.47	GO:0017158	regulation of calcium ion-dependent exocytosis
0.47	GO:0048489	synaptic vesicle transport
0.46	GO:0099504	synaptic vesicle cycle
0.46	GO:0006906	vesicle fusion
0.46	GO:0099643	signal release from synapse
0.46	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.44	GO:0006836	neurotransmitter transport
0.43	GO:0001505	regulation of neurotransmitter levels

0.81	GO:0017137	Rab GTPase binding
0.73	GO:0005543	phospholipid binding
0.47	GO:0019905	syntaxin binding
0.46	GO:0030276	clathrin binding
0.42	GO:0005509	calcium ion binding

0.46	GO:0070382	exocytic vesicle
0.45	GO:0098793	presynapse
0.38	GO:0005886	plasma membrane

tr|R4GGW9|R4GGW9_CHICK
Uncharacterized protein
Search

YRDC

0.95	YrdC domain-containing protein, mitochondrial

0.55	GO:0051051	negative regulation of transport
0.46	GO:0002949	tRNA threonylcarbamoyladenosine modification
0.45	GO:0006450	regulation of translational fidelity

0.74	GO:0003725	double-stranded RNA binding
0.44	GO:0000049	tRNA binding
0.41	GO:0016779	nucleotidyltransferase activity
0.34	GO:0005515	protein binding

0.37	GO:0005737	cytoplasm
0.35	GO:0043227	membrane-bounded organelle
0.35	GO:0043229	intracellular organelle
0.30	GO:0031224	intrinsic component of membrane

0.41

EC:2.7.7

GO:0016779

tr|R4GGX0|R4GGX0_CHICK
Uncharacterized protein
Search

0.20	Kyphoscoliosis peptidase-like

0.85	GO:0007528	neuromuscular junction development
0.81	GO:0007517	muscle organ development
0.61	GO:0006508	proteolysis

0.61

GO:0008233

peptidase activity

0.84	GO:0030018	Z disc
0.69	GO:0005856	cytoskeleton

0.61

GO:0008233

tr|R4GGX4|R4GGX4_CHICK
Olfactory receptor
Search

0.46	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|R4GGX6|R4GGX6_CHICK
Uncharacterized protein
Search

TOMM5

0.97	Translocase of outer mitochondrial membrane 5 homolog

0.43	GO:0006626	protein targeting to mitochondrion
0.38	GO:0016236	macroautophagy

0.41

GO:0008565

protein transporter activity

0.84	GO:0005742	mitochondrial outer membrane translocase complex
0.30	GO:0031224	intrinsic component of membrane

tr|R4GGX8|R4GGX8_CHICK
Uncharacterized protein
Search

0.56	SNF-related serine/threonine-protein kinase

0.63	GO:0006468	protein phosphorylation
0.41	GO:0035556	intracellular signal transduction
0.41	GO:0060217	hemangioblast cell differentiation
0.35	GO:0042981	regulation of apoptotic process
0.34	GO:1901214	regulation of neuron death
0.34	GO:0030099	myeloid cell differentiation
0.34	GO:0043069	negative regulation of programmed cell death

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0000287	magnesium ion binding

0.41	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm

tr|R4GGY0|R4GGY0_CHICK
NAD(P)(+)--arginine ADP-ribosyltransferase
Search

ART1

0.75	Ecto-ADP-ribosyltransferase 4

0.84	GO:0006471	protein ADP-ribosylation
0.35	GO:0046677	response to antibiotic
0.34	GO:0006501	C-terminal protein lipidation
0.34	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0006525	arginine metabolic process

0.85	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity
0.48	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.34	GO:0004984	olfactory receptor activity
0.33	GO:0016787	hydrolase activity

0.48	GO:0031225	anchored component of membrane
0.45	GO:0009986	cell surface
0.38	GO:0033017	sarcoplasmic reticulum membrane
0.38	GO:0044194	cytolytic granule
0.35	GO:0005615	extracellular space
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.85

EC:2.4.2.31

GO:0003956

tr|R4GGZ7|R4GGZ7_CHICK
Uncharacterized protein
Search

0.77	Wilms tumor protein 1-interacting

0.43	GO:0035331	negative regulation of hippo signaling
0.43	GO:2000637	positive regulation of gene silencing by miRNA
0.42	GO:0035195	gene silencing by miRNA
0.41	GO:0001666	response to hypoxia
0.41	GO:1903507	negative regulation of nucleic acid-templated transcription
0.39	GO:0007010	cytoskeleton organization
0.39	GO:0022604	regulation of cell morphogenesis
0.38	GO:0030030	cell projection organization
0.37	GO:0035329	hippo signaling
0.36	GO:0006355	regulation of transcription, DNA-templated

0.54	GO:0046872	metal ion binding
0.41	GO:0003714	transcription corepressor activity
0.36	GO:0005515	protein binding

0.41	GO:0000932	P-body
0.40	GO:0005912	adherens junction
0.39	GO:0005911	cell-cell junction
0.38	GO:0005667	transcription factor complex
0.37	GO:0030055	cell-substrate junction
0.36	GO:0005634	nucleus
0.35	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane
0.33	GO:0036064	ciliary basal body

tr|R4GH07|R4GH07_CHICK
Uncharacterized protein
Search

0.75	BHLH Pancreas specific transcription factor

0.64	GO:0035881	amacrine cell differentiation
0.61	GO:0031016	pancreas development
0.58	GO:0061074	regulation of neural retina development
0.58	GO:0048384	retinoic acid receptor signaling pathway
0.56	GO:0010842	retina layer formation
0.56	GO:0030902	hindbrain development
0.55	GO:0048663	neuron fate commitment
0.54	GO:0045893	positive regulation of transcription, DNA-templated
0.52	GO:0009888	tissue development
0.51	GO:0035272	exocrine system development

0.68	GO:0046983	protein dimerization activity
0.56	GO:0070888	E-box binding
0.54	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0003682	chromatin binding
0.40	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.34	GO:0004634	phosphopyruvate hydratase activity
0.33	GO:0000287	magnesium ion binding
0.33	GO:0005230	extracellular ligand-gated ion channel activity
0.33	GO:0099600	transmembrane receptor activity
0.32	GO:0038023	signaling receptor activity

0.52	GO:0005667	transcription factor complex
0.38	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:1902494	catalytic complex
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

EC:4.2.1.11

GO:0004634

tr|R4GH27|R4GH27_CHICK
Uncharacterized protein
Search

LMOD2

0.94	Leiomodin 2 (cardiac) b

0.85	GO:0051694	pointed-end actin filament capping
0.75	GO:0006936	muscle contraction
0.53	GO:0030239	myofibril assembly
0.51	GO:0045010	actin nucleation
0.47	GO:0030041	actin filament polymerization

0.85	GO:0005523	tropomyosin binding
0.64	GO:0003779	actin binding
0.33	GO:0003677	DNA binding

0.53	GO:0030016	myofibril
0.51	GO:0044449	contractile fiber part
0.48	GO:0015629	actin cytoskeleton
0.46	GO:0044430	cytoskeletal part
0.42	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|R4GH30|R4GH30_CHICK
Uncharacterized protein
Search

NIPAL1

0.91	Non-imprinted in Prader-Willi/Angelman syndrome region protein 3

0.77

GO:1903830

magnesium ion transmembrane transport

0.78	GO:0015095	magnesium ion transmembrane transporter activity
0.33	GO:0005515	protein binding

0.43	GO:0005769	early endosome
0.37	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|R4GH34|R4GH34_CHICK
Uncharacterized protein
Search

tr|R4GH36|R4GH36_CHICK
Uncharacterized protein
Search

SNRPB2

0.89	Small nuclear ribonucleoprotein polypeptide B''

0.44	GO:0000398	mRNA splicing, via spliceosome
0.33	GO:0007165	signal transduction

0.59	GO:0003723	RNA binding
0.39	GO:0070990	snRNP binding
0.35	GO:0005515	protein binding

0.60	GO:0019013	viral nucleocapsid
0.56	GO:0030529	intracellular ribonucleoprotein complex
0.51	GO:0001650	fibrillar center
0.50	GO:0120114	Sm-like protein family complex
0.50	GO:0016607	nuclear speck
0.42	GO:1902494	catalytic complex
0.34	GO:0005911	cell-cell junction
0.30	GO:0016020	membrane

tr|R4GH38|R4GH38_CHICK
Uncharacterized protein
Search

B-G

0.92	BG antigen

0.37	GO:1904622	negative regulation of actin-dependent ATPase activity
0.37	GO:1904616	regulation of actin binding
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.36	GO:0019903	protein phosphatase binding
0.35	GO:0003779	actin binding
0.32	GO:0046872	metal ion binding
0.31	GO:0003676	nucleic acid binding

0.37	GO:0031528	microvillus membrane
0.37	GO:0031526	brush border membrane
0.35	GO:0009986	cell surface
0.34	GO:0005887	integral component of plasma membrane
0.31	GO:0005622	intracellular

tr|R4GH41|R4GH41_CHICK
Uncharacterized protein
Search

ASAH1

0.84	N-acylsphingosine amidohydrolase

0.62	GO:0006629	lipid metabolic process
0.53	GO:0048668	collateral sprouting

0.67

GO:0017040

ceramidase activity

0.78	GO:0005764	lysosome
0.55	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.67

EC:3.5.1.23

GO:0017040

tr|R4GH42|R4GH42_CHICK
Carbohydrate sulfotransferase
Search

CHST14

0.44	Carbohydrate sulfotransferase

0.66	GO:0016051	carbohydrate biosynthetic process
0.57	GO:0050655	dermatan sulfate proteoglycan metabolic process
0.37	GO:0030166	proteoglycan biosynthetic process
0.37	GO:1903510	mucopolysaccharide metabolic process
0.35	GO:0006024	glycosaminoglycan biosynthetic process
0.35	GO:0072330	monocarboxylic acid biosynthetic process
0.35	GO:0044272	sulfur compound biosynthetic process
0.34	GO:0017144	drug metabolic process

0.77	GO:0008146	sulfotransferase activity
0.35	GO:0042301	phosphate ion binding
0.33	GO:0005515	protein binding

0.73	GO:0000139	Golgi membrane
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.77

EC:2.8.2

GO:0008146

tr|R4GH47|R4GH47_CHICK
Uncharacterized protein
Search

OTP

0.97	Homeobox protein orthopedia B

0.68	GO:0007275	multicellular organism development
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:2000648	positive regulation of stem cell proliferation
0.55	GO:2000179	positive regulation of neural precursor cell proliferation
0.54	GO:0060322	head development
0.52	GO:0010720	positive regulation of cell development
0.52	GO:0051962	positive regulation of nervous system development
0.50	GO:0030154	cell differentiation

0.63

GO:0043565

sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|R4GH52|R4GH52_CHICK
Uncharacterized protein
Search

P3H4

0.92	Endoplasmic reticulum protein SC65

0.82	GO:0018126	protein hydroxylation
0.65	GO:0018193	peptidyl-amino acid modification
0.64	GO:0032964	collagen biosynthetic process
0.61	GO:0046849	bone remodeling
0.61	GO:0030199	collagen fibril organization
0.60	GO:0006575	cellular modified amino acid metabolic process
0.55	GO:1901605	alpha-amino acid metabolic process
0.54	GO:1901874	negative regulation of post-translational protein modification
0.49	GO:0050821	protein stabilization
0.47	GO:0061077	chaperone-mediated protein folding

0.46	GO:0032403	protein complex binding
0.39	GO:0045294	alpha-catenin binding
0.38	GO:0045296	cadherin binding
0.35	GO:0004871	signal transducer activity
0.35	GO:0005198	structural molecule activity

0.69	GO:0005783	endoplasmic reticulum
0.47	GO:1902494	catalytic complex
0.47	GO:0005615	extracellular space
0.39	GO:0016342	catenin complex
0.38	GO:0000795	synaptonemal complex
0.38	GO:0005913	cell-cell adherens junction
0.36	GO:0005578	proteinaceous extracellular matrix
0.35	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

tr|R4GH55|R4GH55_CHICK
Uncharacterized protein
Search

0.69	Phosphatase and actin regulator 1 (Fragment)

0.83	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.77	GO:0031532	actin cytoskeleton reorganization
0.53	GO:0043149	stress fiber assembly
0.45	GO:0048870	cell motility
0.37	GO:0042325	regulation of phosphorylation

0.85	GO:0008157	protein phosphatase 1 binding
0.83	GO:0004864	protein phosphatase inhibitor activity
0.74	GO:0003779	actin binding

0.45	GO:0005829	cytosol
0.44	GO:0045202	synapse
0.44	GO:0030054	cell junction
0.42	GO:0005634	nucleus

tr|R4GH61|R4GH61_CHICK
Uncharacterized protein
Search

0.95	Phospholipase C delta 3

0.53	GO:0061743	motor learning
0.53	GO:0099558	maintenance of synapse structure
0.51	GO:0016322	neuron remodeling
0.48	GO:0050807	regulation of synapse organization
0.37	GO:0051259	protein oligomerization
0.35	GO:0007626	locomotory behavior

0.47

GO:0005515

protein binding

0.72	GO:0005581	collagen trimer
0.62	GO:0005576	extracellular region
0.53	GO:0044301	climbing fiber
0.48	GO:0098793	presynapse
0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|R4GH63|R4GH63_CHICK
Uncharacterized protein
Search

CCDC157

0.66	Coiled-coil domain-containing protein 157

0.47	GO:0006013	mannose metabolic process
0.45	GO:0007018	microtubule-based movement

0.47	GO:0004559	alpha-mannosidase activity
0.45	GO:0003777	microtubule motor activity
0.45	GO:0008017	microtubule binding
0.44	GO:0030246	carbohydrate binding
0.39	GO:0030554	adenyl nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding

0.47

EC:3.2.1.24

GO:0004559

tr|R4GH64|R4GH64_CHICK
Uncharacterized protein
Search

CHCHD1

0.96	Coiled-coil-helix-coiled-coil-helix domain-containing protein 1

0.81	GO:0032543	mitochondrial translation
0.35	GO:0006415	translational termination
0.35	GO:0006414	translational elongation

0.35	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.79	GO:0005761	mitochondrial ribosome
0.59	GO:0001650	fibrillar center
0.52	GO:0005654	nucleoplasm
0.51	GO:0005829	cytosol
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane

tr|R4GH65|R4GH65_CHICK
Uncharacterized protein
Search

ECE2

0.43	Endothelin-converting enzyme

0.59	GO:0032259	methylation
0.58	GO:0016486	peptide hormone processing
0.39	GO:0010002	cardioblast differentiation
0.37	GO:0007420	brain development
0.35	GO:0018205	peptidyl-lysine modification
0.35	GO:0008213	protein alkylation
0.35	GO:0042310	vasoconstriction
0.35	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.34	GO:0009792	embryo development ending in birth or egg hatching
0.34	GO:0007267	cell-cell signaling

0.59	GO:0008168	methyltransferase activity
0.50	GO:0004222	metalloendopeptidase activity
0.34	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding

0.47	GO:0030659	cytoplasmic vesicle membrane
0.37	GO:0000139	Golgi membrane
0.35	GO:0005802	trans-Golgi network
0.34	GO:0030133	transport vesicle
0.34	GO:0098805	whole membrane
0.30	GO:0031224	intrinsic component of membrane

0.59

GO:0008168

tr|R4GH67|R4GH67_CHICK
Uncharacterized protein
Search

EOMES

0.96	T-box transcription factor Eomesodermin

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0002302	CD8-positive, alpha-beta T cell differentiation involved in immune response
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0001714	endodermal cell fate specification
0.52	GO:0007420	brain development
0.52	GO:0007498	mesoderm development
0.51	GO:0003002	regionalization
0.50	GO:0048729	tissue morphogenesis

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.47	GO:0001102	RNA polymerase II activating transcription factor binding
0.47	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.46	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0003682	chromatin binding
0.35	GO:0019901	protein kinase binding
0.34	GO:0005452	inorganic anion exchanger activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding

0.61	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|R4GH69|R4GH69_CHICK
Uncharacterized protein
Search

0.89	Retinol dehydrogenase 8

0.84	GO:0006703	estrogen biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.47	GO:0042572	retinol metabolic process
0.44	GO:0007601	visual perception
0.35	GO:0010951	negative regulation of endopeptidase activity
0.34	GO:0006956	complement activation
0.34	GO:0006954	inflammatory response
0.33	GO:0007165	signal transduction

0.83	GO:0004303	estradiol 17-beta-dehydrogenase activity
0.47	GO:0004745	retinol dehydrogenase activity
0.38	GO:0052650	NADP-retinol dehydrogenase activity
0.36	GO:0047035	testosterone dehydrogenase (NAD+) activity
0.35	GO:0004866	endopeptidase inhibitor activity

0.47	GO:0005737	cytoplasm
0.34	GO:0005615	extracellular space
0.34	GO:0001750	photoreceptor outer segment
0.33	GO:0005887	integral component of plasma membrane

0.83	EC:1.1.1.62	GO:0004303
0.38	KEGG:R08379	GO:0052650

tr|R4GH70|R4GH70_CHICK
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|R4GH72|R4GH72_CHICK
Uncharacterized protein
Search

HAPLN4

0.96	Hyaluronan and proteoglycan link protein 4

0.71	GO:0007155	cell adhesion
0.53	GO:0001501	skeletal system development
0.52	GO:0007417	central nervous system development
0.35	GO:0030198	extracellular matrix organization

0.84	GO:0005540	hyaluronic acid binding
0.54	GO:0005201	extracellular matrix structural constituent

0.55	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

tr|R4GH73|R4GH73_CHICK
Uncharacterized protein
Search

0.65	Acyl-coenzyme A thioesterase THEM4

tr|R4GH78|R4GH78_CHICK
Uncharacterized protein
Search

CCR10

0.86	C-C motif chemokine receptor 6

0.72	GO:0070098	chemokine-mediated signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.62	GO:0006935	chemotaxis
0.57	GO:0006955	immune response
0.48	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.48	GO:0006898	receptor-mediated endocytosis
0.46	GO:0007194	negative regulation of adenylate cyclase activity
0.40	GO:0045944	positive regulation of transcription by RNA polymerase II
0.37	GO:0006954	inflammatory response
0.36	GO:0032501	multicellular organismal process

0.73	GO:0004950	chemokine receptor activity
0.55	GO:0019956	chemokine binding
0.52	GO:0005044	scavenger receptor activity
0.47	GO:0004966	galanin receptor activity
0.43	GO:0017046	peptide hormone binding
0.35	GO:0070915	lysophosphatidic acid receptor activity
0.35	GO:0015026	coreceptor activity
0.33	GO:0004982	N-formyl peptide receptor activity
0.33	GO:0004875	complement receptor activity

0.47	GO:0009986	cell surface
0.44	GO:0005783	endoplasmic reticulum
0.42	GO:0097730	non-motile cilium
0.37	GO:0005887	integral component of plasma membrane
0.35	GO:0097524	sperm plasma membrane
0.35	GO:0097225	sperm midpiece
0.35	GO:0097228	sperm principal piece

tr|R4GH80|R4GH80_CHICK
NF-kappa-B inhibitor alpha
Search

NFKBIA

0.97	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

0.85	GO:0007253	cytoplasmic sequestering of NF-kappaB
0.85	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway
0.85	GO:0010745	negative regulation of macrophage derived foam cell differentiation
0.85	GO:0010875	positive regulation of cholesterol efflux
0.85	GO:0010888	negative regulation of lipid storage
0.84	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway
0.83	GO:0035994	response to muscle stretch
0.83	GO:0032495	response to muramyl dipeptide
0.82	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.82	GO:1903707	negative regulation of hemopoiesis

0.84	GO:0051059	NF-kappaB binding
0.82	GO:0008139	nuclear localization sequence binding
0.75	GO:0031625	ubiquitin protein ligase binding
0.70	GO:0042802	identical protein binding
0.43	GO:0031072	heat shock protein binding
0.43	GO:0032403	protein complex binding
0.34	GO:0016301	kinase activity

0.65	GO:0005829	cytosol
0.59	GO:0005634	nucleus
0.54	GO:0005886	plasma membrane
0.44	GO:0033256	I-kappaB/NF-kappaB complex

tr|R4GH84|R4GH84_CHICK
Uncharacterized protein
Search

HIVEP3

0.96	Human immunodeficiency virus type I enhancer binding protein 3

0.72	GO:0035914	skeletal muscle cell differentiation
0.65	GO:0045893	positive regulation of transcription, DNA-templated
0.54	GO:0006366	transcription by RNA polymerase II
0.46	GO:0007165	signal transduction
0.33	GO:0006357	regulation of transcription by RNA polymerase II

0.54	GO:0044212	transcription regulatory region DNA binding
0.48	GO:0043565	sequence-specific DNA binding
0.46	GO:0003700	DNA binding transcription factor activity
0.45	GO:0008270	zinc ion binding
0.34	GO:0003690	double-stranded DNA binding

0.56	GO:0005634	nucleus
0.42	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part

tr|R4GH86|R4GH86_CHICK
Uncharacterized protein
Search

GPX1

0.43	Glutathione peroxidase

0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.53	GO:0009609	response to symbiotic bacterium
0.52	GO:0055114	oxidation-reduction process
0.52	GO:0051450	myoblast proliferation
0.52	GO:0010269	response to selenium ion
0.52	GO:0002862	negative regulation of inflammatory response to antigenic stimulus
0.51	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.51	GO:0043403	skeletal muscle tissue regeneration
0.51	GO:0060055	angiogenesis involved in wound healing

0.79	GO:0004602	glutathione peroxidase activity
0.47	GO:0017124	SH3 domain binding
0.37	GO:0003924	GTPase activity
0.36	GO:0005525	GTP binding
0.35	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.34	GO:0031685	adenosine receptor binding
0.33	GO:0008430	selenium binding
0.33	GO:0042802	identical protein binding

0.51	GO:0097413	Lewy body
0.44	GO:0005829	cytosol
0.41	GO:0005739	mitochondrion
0.39	GO:0097524	sperm plasma membrane
0.38	GO:0005615	extracellular space
0.35	GO:1903561	extracellular vesicle
0.33	GO:0005634	nucleus
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part

0.79

EC:1.11.1.9

GO:0004602

tr|R4GH87|R4GH87_CHICK
Uncharacterized protein
Search

LYRM4

0.61	LYR motif-containing protein 4

0.61	GO:0005739	mitochondrion
0.48	GO:0005634	nucleus

tr|R4GH91|R4GH91_CHICK
Uncharacterized protein
Search

0.97	Gastrin/cholecystokinin-like peptide

0.76	GO:0010469	regulation of receptor activity
0.65	GO:0007586	digestion

0.79

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

tr|R4GH93|R4GH93_CHICK
Uncharacterized protein
Search

tr|R4GH95|R4GH95_CHICK
Uncharacterized protein
Search

GPRIN3

0.93	G protein-regulated inducer of neurite outgrowth 3

0.61	GO:0031175	neuron projection development
0.47	GO:0022900	electron transport chain

0.48	GO:0020037	heme binding
0.48	GO:0009055	electron transfer activity
0.44	GO:0051219	phosphoprotein binding
0.43	GO:0046872	metal ion binding

0.51	GO:0030426	growth cone
0.46	GO:0005886	plasma membrane

tr|R4GH98|R4GH98_CHICK
Uncharacterized protein
Search

CRLF1

0.97	Class I helical cytokine receptor number 1

0.85	GO:2000672	negative regulation of motor neuron apoptotic process
0.81	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.80	GO:0001657	ureteric bud development
0.74	GO:0008284	positive regulation of cell proliferation
0.70	GO:0010469	regulation of receptor activity
0.43	GO:0070106	interleukin-27-mediated signaling pathway

0.85	GO:0005127	ciliary neurotrophic factor receptor binding
0.78	GO:0019955	cytokine binding
0.75	GO:0005125	cytokine activity
0.69	GO:0046982	protein heterodimerization activity

0.85	GO:0097058	CRLF-CLCF1 complex
0.38	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|R4GHA7|R4GHA7_CHICK
Uncharacterized protein
Search

TRIM62

0.87	Tripartite motif-containing protein 62

0.60	GO:0046596	regulation of viral entry into host cell
0.60	GO:0032897	negative regulation of viral transcription
0.60	GO:1902186	regulation of viral release from host cell
0.60	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.58	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.58	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.55	GO:0045087	innate immune response
0.52	GO:0016567	protein ubiquitination
0.36	GO:0010033	response to organic substance
0.35	GO:0007166	cell surface receptor signaling pathway

0.60	GO:0008270	zinc ion binding
0.52	GO:0004842	ubiquitin-protein transferase activity
0.44	GO:0016874	ligase activity

0.44	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.44	EC:6	GO:0016874
0.52	KEGG:R03876	GO:0004842

tr|R4GHA8|R4GHA8_CHICK
Uncharacterized protein
Search

TMEM213

0.97	Transmembrane protein 213

0.30

GO:0044425

membrane part

tr|R4GHB0|R4GHB0_CHICK
Uncharacterized protein
Search

PITPNC1

0.92	cytoplasmic phosphatidylinositol transfer protein 1

0.79	GO:0015914	phospholipid transport
0.42	GO:0007165	signal transduction
0.34	GO:0046488	phosphatidylinositol metabolic process

0.80	GO:0005548	phospholipid transporter activity
0.53	GO:1901611	phosphatidylglycerol binding
0.52	GO:0070300	phosphatidic acid binding
0.47	GO:0035091	phosphatidylinositol binding
0.33	GO:0005515	protein binding

0.46	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol

tr|R4GHB4|R4GHB4_CHICK
Uncharacterized protein
Search

0.72	Hepatocyte cell adhesion molecule

0.41

GO:0006898

receptor-mediated endocytosis

0.43

GO:0005044

scavenger receptor activity

0.30

GO:0044425

membrane part

tr|R4GHB5|R4GHB5_CHICK
Rhomboid-like protein
Search

RHBDL1

0.78	Rhomboid-related protein 1

0.64	GO:0016485	protein processing
0.45	GO:0007165	signal transduction

0.69	GO:0004252	serine-type endopeptidase activity
0.49	GO:0005509	calcium ion binding
0.48	GO:0003924	GTPase activity
0.47	GO:0005525	GTP binding

0.48

GO:0005887

integral component of plasma membrane

0.69

GO:0004252

tr|R4GHC2|R4GHC2_CHICK
Uncharacterized protein
Search

0.96	Myosin-M heavy chain

0.78	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.43	GO:0035277	spiracle morphogenesis, open tracheal system
0.42	GO:0007480	imaginal disc-derived leg morphogenesis
0.42	GO:0046579	positive regulation of Ras protein signal transduction
0.41	GO:0007411	axon guidance
0.34	GO:0060271	cilium assembly
0.32	GO:0006468	protein phosphorylation

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.34	GO:0005516	calmodulin binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0045179	apical cortex
0.30	GO:0016020	membrane

tr|R4GHC5|R4GHC5_CHICK
Uncharacterized protein
Search

0.10	von Willebrand factor A domain-containing protein 5A (Fragment)

0.48	GO:0060923	cardiac muscle cell fate commitment
0.38	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.37	GO:0007186	G-protein coupled receptor signaling pathway

0.38	GO:0004984	olfactory receptor activity
0.37	GO:0004930	G-protein coupled receptor activity

0.60	GO:0005654	nucleoplasm
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|R4GHD2|R4GHD2_CHICK
Uncharacterized protein
Search

UQCRQ

0.94	Mitochondrial ubiquinol-cytochrome c reductase ubiquinone-binding protein qp-c

0.61	GO:0022900	electron transport chain
0.58	GO:0021539	subthalamus development
0.57	GO:0021860	pyramidal neuron development
0.56	GO:0021794	thalamus development
0.56	GO:0021548	pons development
0.55	GO:0021854	hypothalamus development
0.55	GO:0021680	cerebellar Purkinje cell layer development
0.54	GO:0030901	midbrain development
0.54	GO:0021766	hippocampus development
0.41	GO:0006119	oxidative phosphorylation

0.74	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.62	GO:0009055	electron transfer activity
0.37	GO:0005230	extracellular ligand-gated ion channel activity
0.36	GO:0004888	transmembrane signaling receptor activity
0.36	GO:0048039	ubiquinone binding
0.33	GO:0005515	protein binding

0.48	GO:0005750	mitochondrial respiratory chain complex III
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.74

EC:1.10.2

GO:0016681

tr|R4GHD4|R4GHD4_CHICK
Uncharacterized protein
Search

CIDEC

0.97	Cell death inducing DFFA like effector c

0.77	GO:0006915	apoptotic process
0.50	GO:0019915	lipid storage
0.49	GO:0042981	regulation of apoptotic process
0.46	GO:1903624	regulation of DNA catabolic process
0.46	GO:0010890	positive regulation of sequestering of triglyceride
0.46	GO:0050995	negative regulation of lipid catabolic process
0.46	GO:0035634	response to stilbenoid
0.45	GO:0032720	negative regulation of tumor necrosis factor production
0.45	GO:0050710	negative regulation of cytokine secretion
0.45	GO:0001659	temperature homeostasis

0.42	GO:0042803	protein homodimerization activity
0.32	GO:0009982	pseudouridine synthase activity
0.32	GO:0003723	RNA binding

0.56	GO:0005811	lipid droplet
0.40	GO:0005634	nucleus
0.38	GO:0005740	mitochondrial envelope
0.38	GO:0005829	cytosol
0.37	GO:0005783	endoplasmic reticulum

0.32

EC:5.4.99.12

GO:0009982

tr|R4GHD9|R4GHD9_CHICK
Docking protein 3
Search

DOK3

0.89	Docking protein 3

0.72	GO:0007265	Ras protein signal transduction
0.69	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.42	GO:0050900	leukocyte migration
0.42	GO:0007411	axon guidance

0.76	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity
0.70	GO:0005057	signal transducer activity, downstream of receptor

0.47	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane
0.42	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|R4GHE6|R4GHE6_CHICK
Uncharacterized protein
Search

SDHAF3

0.91	Succinate dehydrogenase complex assembly factor 3

0.64	GO:0097032	mitochondrial respiratory chain complex II biogenesis
0.64	GO:0034552	respiratory chain complex II assembly
0.61	GO:0006111	regulation of gluconeogenesis
0.59	GO:0033108	mitochondrial respiratory chain complex assembly
0.59	GO:0006105	succinate metabolic process
0.53	GO:0006979	response to oxidative stress

0.61	GO:0005739	mitochondrion
0.58	GO:0031970	organelle envelope lumen

tr|R4GHF3|R4GHF3_CHICK
Uncharacterized protein
Search

SERTAD2

0.97	SERTA domain-containing protein 2

0.83	GO:0030308	negative regulation of cell growth
0.72	GO:0045893	positive regulation of transcription, DNA-templated
0.37	GO:0006351	transcription, DNA-templated
0.34	GO:0051301	cell division

0.78	GO:0003713	transcription coactivator activity
0.36	GO:0005515	protein binding

0.68	GO:0005654	nucleoplasm
0.67	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|R4GHF6|R4GHF6_CHICK
Uncharacterized protein
Search

0.75	GO:0010764	negative regulation of fibroblast migration
0.74	GO:1900016	negative regulation of cytokine production involved in inflammatory response
0.54	GO:0060271	cilium assembly
0.52	GO:0070121	Kupffer's vesicle development
0.43	GO:0015031	protein transport
0.37	GO:0016310	phosphorylation

0.44	GO:0000829	inositol heptakisphosphate kinase activity
0.35	GO:0005515	protein binding

0.80	GO:0035869	ciliary transition zone
0.47	GO:0005737	cytoplasm

tr|R4GHG2|R4GHG2_CHICK
Uncharacterized protein
Search

HES5

0.96	Transcription factor HES-5

0.57	GO:0006351	transcription, DNA-templated
0.56	GO:0006355	regulation of transcription, DNA-templated
0.48	GO:0072086	specification of loop of Henle identity
0.48	GO:0042668	auditory receptor cell fate determination
0.48	GO:0045632	negative regulation of mechanoreceptor differentiation
0.48	GO:0072049	comma-shaped body morphogenesis
0.48	GO:0072050	S-shaped body morphogenesis
0.48	GO:0072282	metanephric nephron tubule morphogenesis
0.48	GO:0045607	regulation of inner ear auditory receptor cell differentiation
0.47	GO:0048712	negative regulation of astrocyte differentiation

0.68	GO:0046983	protein dimerization activity
0.54	GO:0003677	DNA binding
0.46	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0003682	chromatin binding
0.34	GO:0008134	transcription factor binding

0.60	GO:0005634	nucleus
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part

tr|R4GHG3|R4GHG3_CHICK
Uncharacterized protein
Search

TMEM100

0.52	Transmembrane domain-containing protein (Fragment)

0.61	GO:0060842	arterial endothelial cell differentiation
0.61	GO:2001214	positive regulation of vasculogenesis
0.60	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation
0.60	GO:0045603	positive regulation of endothelial cell differentiation
0.60	GO:0051930	regulation of sensory perception of pain
0.59	GO:0043491	protein kinase B signaling
0.58	GO:0030509	BMP signaling pathway
0.57	GO:0001570	vasculogenesis
0.57	GO:0050848	regulation of calcium-mediated signaling
0.56	GO:0007219	Notch signaling pathway

0.34

GO:0005515

protein binding

0.59	GO:0043204	perikaryon
0.55	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005783	endoplasmic reticulum
0.43	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|R4GHH2|R4GHH2_CHICK
Uncharacterized protein
Search

WASHC4

0.96	WASH complex subunit 4

0.54	GO:0016197	endosomal transport
0.50	GO:0007032	endosome organization
0.34	GO:0015031	protein transport

0.84	GO:0071203	WASH complex
0.53	GO:0005768	endosome
0.48	GO:0005654	nucleoplasm
0.38	GO:0031083	BLOC-1 complex
0.30	GO:0016020	membrane

tr|R4GHH3|R4GHH3_CHICK
Uncharacterized protein
Search

RUNDC3A

0.97	RUN domain-containing protein 3A

0.86	GO:0031284	positive regulation of guanylate cyclase activity
0.57	GO:0007264	small GTPase mediated signal transduction

0.86	GO:0030250	guanylate cyclase activator activity
0.86	GO:0051428	peptide hormone receptor binding
0.57	GO:0030695	GTPase regulator activity

0.69	GO:0005829	cytosol
0.56	GO:0005886	plasma membrane

tr|R4GHI3|R4GHI3_CHICK
Uncharacterized protein
Search

ANKRD40

0.95	Ankyrin repeat domain-containing protein 40

0.49

GO:0005515

protein binding

0.30

GO:0044425

membrane part

tr|R4GHI8|R4GHI8_CHICK
Uncharacterized protein
Search

HOXA1

0.97	Homeobox protein Hox-A1

0.63	GO:0021598	abducens nerve morphogenesis
0.62	GO:0060876	semicircular canal formation
0.61	GO:0042473	outer ear morphogenesis
0.61	GO:0007634	optokinetic behavior
0.61	GO:0021603	cranial nerve formation
0.61	GO:0048702	embryonic neurocranium morphogenesis
0.60	GO:0090103	cochlea morphogenesis
0.58	GO:0048844	artery morphogenesis
0.58	GO:0050905	neuromuscular process
0.57	GO:0050795	regulation of behavior

0.65	GO:0043565	sequence-specific DNA binding
0.52	GO:0042802	identical protein binding
0.35	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

tr|R4GHJ0|R4GHJ0_CHICK
Uncharacterized protein
Search

GPR132

0.79	Truncated G protein-coupled receptor 132

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.55	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle
0.55	GO:0000082	G1/S transition of mitotic cell cycle
0.50	GO:0032098	regulation of appetite
0.49	GO:0007210	serotonin receptor signaling pathway
0.46	GO:0007268	chemical synaptic transmission
0.40	GO:0006935	chemotaxis
0.38	GO:0071310	cellular response to organic substance
0.38	GO:0007166	cell surface receptor signaling pathway
0.37	GO:0032959	inositol trisphosphate biosynthetic process

0.72	GO:0004930	G-protein coupled receptor activity
0.49	GO:0099589	serotonin receptor activity
0.46	GO:0030594	neurotransmitter receptor activity
0.37	GO:0001653	peptide receptor activity
0.37	GO:0004896	cytokine receptor activity
0.37	GO:0001875	lipopolysaccharide receptor activity
0.36	GO:0001530	lipopolysaccharide binding
0.36	GO:0019956	chemokine binding
0.35	GO:0005543	phospholipid binding
0.34	GO:0001614	purinergic nucleotide receptor activity

0.44	GO:0005887	integral component of plasma membrane
0.35	GO:0097524	sperm plasma membrane
0.34	GO:0097225	sperm midpiece
0.34	GO:0097228	sperm principal piece
0.34	GO:0005622	intracellular
0.34	GO:0009986	cell surface
0.33	GO:0031982	vesicle
0.33	GO:0012505	endomembrane system

tr|R4GHJ8|R4GHJ8_CHICK
Uncharacterized protein
Search

KLF4

0.96	Kruppel like factor 4

0.59	GO:0071499	cellular response to laminar fluid shear stress
0.58	GO:1904998	negative regulation of leukocyte adhesion to arterial endothelial cell
0.58	GO:2000342	negative regulation of chemokine (C-X-C motif) ligand 2 production
0.58	GO:0046985	positive regulation of hemoglobin biosynthetic process
0.58	GO:0045415	negative regulation of interleukin-8 biosynthetic process
0.57	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.57	GO:0061614	pri-miRNA transcription by RNA polymerase II
0.56	GO:0034115	negative regulation of heterotypic cell-cell adhesion
0.56	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis
0.56	GO:0031077	post-embryonic camera-type eye development

0.55	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting
0.55	GO:1990841	promoter-specific chromatin binding
0.54	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.53	GO:0001085	RNA polymerase II transcription factor binding
0.52	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0008013	beta-catenin binding
0.52	GO:0001047	core promoter binding
0.51	GO:0000987	proximal promoter sequence-specific DNA binding
0.40	GO:0001221	transcription cofactor binding
0.39	GO:0035014	phosphatidylinositol 3-kinase regulator activity

0.53	GO:0005719	nuclear euchromatin
0.49	GO:0044798	nuclear transcription factor complex
0.47	GO:0005654	nucleoplasm
0.38	GO:0005737	cytoplasm

tr|R4GHL2|R4GHL2_CHICK
Protein kinase C
Search

PRKCA

0.76	Protein kinase C alpha type

0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.59	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway
0.59	GO:0034351	negative regulation of glial cell apoptotic process
0.58	GO:0090330	regulation of platelet aggregation
0.57	GO:0002159	desmosome assembly
0.56	GO:0001938	positive regulation of endothelial cell proliferation
0.56	GO:0010595	positive regulation of endothelial cell migration
0.56	GO:0045766	positive regulation of angiogenesis
0.56	GO:0018210	peptidyl-threonine modification

0.82	GO:0004697	protein kinase C activity
0.61	GO:0008270	zinc ion binding
0.60	GO:0035403	histone kinase activity (H3-T6 specific)
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.49	GO:0019899	enzyme binding
0.38	GO:0009931	calcium-dependent protein serine/threonine kinase activity
0.38	GO:0050681	androgen receptor binding

0.49	GO:0005829	cytosol
0.48	GO:0005783	endoplasmic reticulum
0.48	GO:0005886	plasma membrane
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0001750	photoreceptor outer segment
0.37	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.36	GO:0043025	neuronal cell body
0.36	GO:0030425	dendrite
0.36	GO:0045177	apical part of cell

0.82

EC:2.7.11.13

GO:0004697

tr|R4GHL6|R4GHL6_CHICK
Uncharacterized protein
Search

NABP1

0.97	Nucleic acid binding protein 1

0.66	GO:0010212	response to ionizing radiation
0.64	GO:0007093	mitotic cell cycle checkpoint
0.62	GO:0000724	double-strand break repair via homologous recombination
0.60	GO:0070200	establishment of protein localization to telomere
0.59	GO:1904355	positive regulation of telomere capping
0.38	GO:0042795	snRNA transcription by RNA polymerase II
0.37	GO:0051972	regulation of telomerase activity
0.35	GO:0030001	metal ion transport
0.33	GO:0055085	transmembrane transport

0.60	GO:0003697	single-stranded DNA binding
0.58	GO:0070182	DNA polymerase binding
0.55	GO:0042162	telomeric DNA binding
0.44	GO:0003723	RNA binding
0.35	GO:0046873	metal ion transmembrane transporter activity

0.70	GO:0070876	SOSS complex
0.65	GO:0000784	nuclear chromosome, telomeric region
0.57	GO:0005654	nucleoplasm
0.56	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|R4GHL8|R4GHL8_CHICK
Uncharacterized protein
Search

0.86	GO:0021895	cerebral cortex neuron differentiation
0.86	GO:0060999	positive regulation of dendritic spine development

0.36

GO:0005515

protein binding

tr|R4GHM1|R4GHM1_CHICK
Uncharacterized protein
Search

CTTNBP2NL

0.94	CTTNBP2 N-terminal like

0.83	GO:0032410	negative regulation of transporter activity
0.82	GO:0034763	negative regulation of transmembrane transport
0.71	GO:0006470	protein dephosphorylation

0.84

GO:0051721

protein phosphatase 2A binding

0.71	GO:0015629	actin cytoskeleton
0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|R4GHM5|R4GHM5_CHICK
Uncharacterized protein
Search

0.91	Coagulation factor VIII-associated 2

0.40

GO:0006012

galactose metabolic process

0.40	GO:0003978	UDP-glucose 4-epimerase activity
0.37	GO:0050662	coenzyme binding

0.50	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.40

EC:5.1.3.2

GO:0003978

tr|R4GHM6|R4GHM6_CHICK
Uncharacterized protein
Search

KCNK3

0.93	Potassium two pore domain channel subfamily K member 3

0.71	GO:0071805	potassium ion transmembrane transport
0.62	GO:0010469	regulation of receptor activity
0.52	GO:0030322	stabilization of membrane potential
0.43	GO:0060047	heart contraction
0.38	GO:0051481	negative regulation of cytosolic calcium ion concentration
0.38	GO:0071294	cellular response to zinc ion
0.38	GO:0090102	cochlea development
0.37	GO:0071456	cellular response to hypoxia
0.37	GO:0007420	brain development
0.35	GO:0042493	response to drug

0.75	GO:0005252	open rectifier potassium channel activity
0.64	GO:0008083	growth factor activity
0.58	GO:0022841	potassium ion leak channel activity
0.53	GO:0044548	S100 protein binding
0.39	GO:0042803	protein homodimerization activity
0.39	GO:0046982	protein heterodimerization activity
0.37	GO:0008022	protein C-terminus binding
0.33	GO:0004930	G-protein coupled receptor activity

0.61	GO:0005615	extracellular space
0.44	GO:0005887	integral component of plasma membrane
0.38	GO:0008021	synaptic vesicle

tr|R4GHM9|R4GHM9_CHICK
Uncharacterized protein
Search

NDUFAF2

0.97	NADH:ubiquinone oxidoreductase complex assembly factor 2

0.69	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus
0.60	GO:0022900	electron transport chain
0.57	GO:0072593	reactive oxygen species metabolic process
0.52	GO:0045333	cellular respiration

0.68	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.61	GO:0009055	electron transfer activity

0.53	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.68

EC:1.6.5.3

GO:0008137

tr|R4GHN1|R4GHN1_CHICK
Uncharacterized protein
Search

ALOX5AP

0.97	Arachidonate 5-lipoxygenase-activating protein isoform 1

0.86	GO:0006691	leukotriene metabolic process
0.73	GO:0043085	positive regulation of catalytic activity
0.64	GO:0002540	leukotriene production involved in inflammatory response
0.63	GO:0046456	icosanoid biosynthetic process
0.44	GO:0001525	angiogenesis
0.41	GO:0019372	lipoxygenase pathway
0.41	GO:0070207	protein homotrimerization
0.39	GO:0002675	positive regulation of acute inflammatory response
0.39	GO:0071277	cellular response to calcium ion
0.36	GO:2001300	lipoxin metabolic process

0.75	GO:0008047	enzyme activator activity
0.52	GO:0004464	leukotriene-C4 synthase activity
0.48	GO:0004364	glutathione transferase activity
0.48	GO:0004602	glutathione peroxidase activity
0.47	GO:0050544	arachidonic acid binding
0.40	GO:0004051	arachidonate 5-lipoxygenase activity
0.39	GO:0047485	protein N-terminus binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity
0.37	GO:0019899	enzyme binding

0.48	GO:0005634	nucleus
0.46	GO:0005783	endoplasmic reticulum
0.43	GO:0031967	organelle envelope
0.42	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.41	GO:0031984	organelle subcompartment
0.39	GO:0031090	organelle membrane
0.36	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.52	EC:4.4.1.20	GO:0004464
0.52	KEGG:R03059	GO:0004464

tr|R4GHN2|R4GHN2_CHICK
Uncharacterized protein
Search

METRNL

0.96	Meteorin like, glial cell differentiation regulator

0.87	GO:2000507	positive regulation of energy homeostasis
0.86	GO:0090336	positive regulation of brown fat cell differentiation
0.86	GO:0014850	response to muscle activity
0.84	GO:0050728	negative regulation of inflammatory response
0.84	GO:0045444	fat cell differentiation
0.80	GO:0009409	response to cold
0.75	GO:0010469	regulation of receptor activity
0.40	GO:0050772	positive regulation of axonogenesis
0.39	GO:0010001	glial cell differentiation

0.78

GO:0005179

hormone activity

0.73	GO:0005615	extracellular space
0.47	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

tr|R4GHN4|R4GHN4_CHICK
Uncharacterized protein
Search

0.65	Cytosolic phospholipase A2 epsilon

0.80	GO:0009395	phospholipid catabolic process
0.35	GO:0036150	phosphatidylserine acyl-chain remodeling
0.35	GO:0036152	phosphatidylethanolamine acyl-chain remodeling
0.35	GO:0036149	phosphatidylinositol acyl-chain remodeling
0.35	GO:0036151	phosphatidylcholine acyl-chain remodeling

0.81	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.81	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.78	GO:0004623	phospholipase A2 activity
0.52	GO:0046872	metal ion binding
0.35	GO:0008970	phosphatidylcholine 1-acylhydrolase activity
0.34	GO:0004622	lysophospholipase activity

0.48	GO:0005737	cytoplasm
0.34	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.32	GO:0044446	intracellular organelle part
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.78

GO:0004623

tr|R4GHN7|R4GHN7_CHICK
Uncharacterized protein
Search

ZFYVE26

0.92	LOW QUALITY PROTEIN: zinc finger FYVE domain-containing protein 26

0.77	GO:0000724	double-strand break repair via homologous recombination
0.73	GO:0000910	cytokinesis
0.57	GO:0032465	regulation of cytokinesis
0.40	GO:0048599	oocyte development
0.40	GO:0007409	axonogenesis

0.83	GO:0032266	phosphatidylinositol-3-phosphate binding
0.51	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.59	GO:0030496	midbody
0.56	GO:0005813	centrosome
0.37	GO:0005765	lysosomal membrane
0.30	GO:0031224	intrinsic component of membrane

tr|R4GHN9|R4GHN9_CHICK
Uncharacterized protein
Search

LUZP1

0.97	Leucine zipper protein 1

0.88	GO:0021503	neural fold bending
0.85	GO:0003281	ventricular septum development
0.84	GO:0060840	artery development

0.61	GO:0005634	nucleus
0.45	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

tr|R4GHP1|R4GHP1_CHICK
Uncharacterized protein
Search

PERP

0.97	PERP, TP53 apoptosis effector

0.50	GO:0097202	activation of cysteine-type endopeptidase activity
0.48	GO:0002934	desmosome organization
0.48	GO:0097186	amelogenesis
0.47	GO:0034113	heterotypic cell-cell adhesion
0.46	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.45	GO:0007219	Notch signaling pathway
0.38	GO:1902262	apoptotic process involved in blood vessel morphogenesis
0.37	GO:0009411	response to UV
0.37	GO:0042981	regulation of apoptotic process
0.35	GO:0070268	cornification

0.42	GO:0005794	Golgi apparatus
0.41	GO:0005887	integral component of plasma membrane
0.39	GO:0005739	mitochondrion
0.36	GO:0030057	desmosome

tr|R4GHP2|R4GHP2_CHICK
Uncharacterized protein
Search

TMEM159

0.97	Promethin-A

0.30

GO:0044425

membrane part

tr|R4GHQ0|R4GHQ0_CHICK
Uncharacterized protein
Search

0.56	GO:0007049	cell cycle
0.49	GO:0097722	sperm motility
0.36	GO:0051301	cell division
0.36	GO:0007283	spermatogenesis
0.35	GO:0030154	cell differentiation

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0042802	identical protein binding
0.45	GO:0046983	protein dimerization activity
0.35	GO:0035091	phosphatidylinositol binding

0.54	GO:0097227	sperm annulus
0.52	GO:0031105	septin complex
0.51	GO:0030496	midbody
0.49	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0005819	spindle
0.36	GO:0097517	contractile actin filament bundle
0.36	GO:0032154	cleavage furrow
0.36	GO:0042641	actomyosin
0.36	GO:0045202	synapse
0.36	GO:0030054	cell junction

tr|R4GHQ6|R4GHQ6_CHICK
Uncharacterized protein
Search

ST8SIA4

0.97	Polysialic acid synthase

0.83	GO:0097503	sialylation
0.74	GO:0006486	protein glycosylation
0.66	GO:0001574	ganglioside biosynthetic process
0.62	GO:0006491	N-glycan processing
0.54	GO:0009311	oligosaccharide metabolic process
0.36	GO:0007162	negative regulation of cell adhesion
0.35	GO:0007399	nervous system development

0.84	GO:0008373	sialyltransferase activity
0.37	GO:0033691	sialic acid binding
0.34	GO:0005515	protein binding

0.70	GO:0005794	Golgi apparatus
0.45	GO:0055037	recycling endosome
0.45	GO:0005769	early endosome
0.39	GO:0098588	bounding membrane of organelle
0.38	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.84

EC:2.4.99

GO:0008373

tr|R4GHQ7|R4GHQ7_CHICK
Uncharacterized protein
Search

AMMECR1L

0.97	AMME chromosomal region gene 1-like isoform X

0.56	GO:0005634	nucleus
0.30	GO:0044425	membrane part

tr|R4GHQ9|R4GHQ9_CHICK
Uncharacterized protein
Search

SAYSD1

0.96	SAYSvFN domain-containing protein 1

0.34

GO:0046854

phosphatidylinositol phosphorylation

0.42	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0030659	cytoplasmic vesicle membrane
0.30	GO:0031224	intrinsic component of membrane

tr|R4GHR0|R4GHR0_CHICK
Glutaredoxin-like protein
Search

0.96	Glutaredoxin-like protein (Fragment)

0.50	GO:0055114	oxidation-reduction process
0.35	GO:0045454	cell redox homeostasis
0.34	GO:0006091	generation of precursor metabolites and energy

0.44	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.35	GO:0015035	protein disulfide oxidoreductase activity
0.34	GO:0009055	electron transfer activity

0.43	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

0.44

EC:2.3.1

GO:0016747

tr|R4GHR7|R4GHR7_CHICK
Uncharacterized protein
Search

0.10	Heat shock transcription factor (Fragment)

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.33	GO:0046872	metal ion binding

0.61

GO:0005634

nucleus

tr|R4GHS3|R4GHS3_CHICK
Uncharacterized protein
Search

NXNL2

0.64	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen domain containing protein

0.74	GO:0045494	photoreceptor cell maintenance
0.64	GO:0045454	cell redox homeostasis
0.63	GO:0007600	sensory perception
0.44	GO:0098869	cellular oxidant detoxification
0.34	GO:0035556	intracellular signal transduction
0.33	GO:0019068	virion assembly
0.33	GO:0055114	oxidation-reduction process
0.33	GO:0006091	generation of precursor metabolites and energy

0.48	GO:0004791	thioredoxin-disulfide reductase activity
0.35	GO:0047134	protein-disulfide reductase activity
0.34	GO:0016746	transferase activity, transferring acyl groups
0.34	GO:0016853	isomerase activity
0.34	GO:0015035	protein disulfide oxidoreductase activity
0.33	GO:0009055	electron transfer activity
0.32	GO:0003676	nucleic acid binding

0.37	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.48	EC:1.8.1.9	GO:0004791
0.48	KEGG:R02016	GO:0004791

tr|R4GHS8|R4GHS8_CHICK
Uncharacterized protein
Search

INA

0.66	Alpha-internexin

0.71	GO:0007399	nervous system development
0.68	GO:0120036	plasma membrane bounded cell projection organization
0.67	GO:0048468	cell development
0.50	GO:0033693	neurofilament bundle assembly
0.49	GO:1902513	regulation of organelle transport along microtubule
0.46	GO:1990830	cellular response to leukemia inhibitory factor
0.44	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.43	GO:0000226	microtubule cytoskeleton organization
0.36	GO:0006334	nucleosome assembly
0.35	GO:1903937	response to acrylamide

0.62	GO:0005198	structural molecule activity
0.44	GO:0019901	protein kinase binding
0.35	GO:0030674	protein binding, bridging
0.34	GO:0008017	microtubule binding
0.34	GO:0005219	ryanodine-sensitive calcium-release channel activity
0.34	GO:0019894	kinesin binding
0.34	GO:0070840	dynein complex binding
0.34	GO:0015643	toxic substance binding
0.33	GO:0003677	DNA binding
0.33	GO:0046982	protein heterodimerization activity

0.83	GO:0005883	neurofilament
0.53	GO:0097418	neurofibrillary tangle
0.45	GO:0043209	myelin sheath
0.45	GO:0014069	postsynaptic density
0.44	GO:0030424	axon
0.38	GO:0005739	mitochondrion
0.36	GO:0000786	nucleosome
0.35	GO:0031965	nuclear membrane
0.35	GO:0036464	cytoplasmic ribonucleoprotein granule
0.34	GO:0005654	nucleoplasm

tr|R4GHT6|R4GHT6_CHICK
Cerebellar degeneration-related protein 2
Search

CDR2

0.97	Paraneoplastic cerebellar degeneration-associated antigen

0.36

GO:0006457

protein folding

0.38

GO:0005515

protein binding

0.48	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|R4GHT9|R4GHT9_CHICK
Uncharacterized protein
Search

tr|R4GHU0|R4GHU0_CHICK
Uncharacterized protein
Search

MAD2L1BP

0.97	MAD2L1-binding protein isoform 1

0.84	GO:0007096	regulation of exit from mitosis
0.57	GO:0007093	mitotic cell cycle checkpoint
0.35	GO:0071173	spindle assembly checkpoint
0.35	GO:0045841	negative regulation of mitotic metaphase/anaphase transition

0.35

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.50	GO:0012505	endomembrane system
0.50	GO:0031974	membrane-enclosed lumen
0.47	GO:0031967	organelle envelope
0.47	GO:0031090	organelle membrane
0.46	GO:0043232	intracellular non-membrane-bounded organelle
0.40	GO:0005737	cytoplasm

tr|R4GHU7|R4GHU7_CHICK
Uncharacterized protein
Search

SLC17A9

0.97	Solute carrier family 17 (vesicular nucleotide transporter), member 9b

0.54	GO:1903146	regulation of autophagy of mitochondrion
0.53	GO:1903955	positive regulation of protein targeting to mitochondrion
0.53	GO:0055085	transmembrane transport
0.41	GO:0006820	anion transport
0.36	GO:0006887	exocytosis

0.54

GO:0005215

transporter activity

0.30

GO:0016021

integral component of membrane

tr|R4GHV0|R4GHV0_CHICK
Uncharacterized protein
Search

OLFML1

0.97	Olfactomedin like 1

0.62	GO:0051492	regulation of stress fiber assembly
0.62	GO:0001952	regulation of cell-matrix adhesion
0.59	GO:0030335	positive regulation of cell migration

0.59	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

tr|R4GHV2|R4GHV2_CHICK
DCN1-like protein
Search

tr|R4GHV4|R4GHV4_CHICK
Uncharacterized protein
Search

RLBP1

0.97	Retinaldehyde-binding protein 1

0.78	GO:0007601	visual perception
0.38	GO:0006776	vitamin A metabolic process
0.36	GO:0050896	response to stimulus

0.86	GO:0016918	retinal binding
0.43	GO:0019841	retinol binding

0.39	GO:0044297	cell body
0.35	GO:0005829	cytosol

tr|R4GHW2|R4GHW2_CHICK
Uncharacterized protein
Search

LYPD6B

0.97	Ly6/PLAUR domain-containing protein 6B

0.79	GO:0099601	regulation of neurotransmitter receptor activity
0.55	GO:2000272	negative regulation of receptor activity
0.45	GO:0060827	regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation
0.44	GO:2000053	regulation of Wnt signaling pathway involved in dorsal/ventral axis specification
0.43	GO:0060061	Spemann organizer formation
0.42	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.38	GO:0006501	C-terminal protein lipidation

0.80	GO:0030548	acetylcholine receptor regulator activity
0.55	GO:0030547	receptor inhibitor activity
0.34	GO:0005515	protein binding

0.47	GO:0031225	anchored component of membrane
0.39	GO:0005886	plasma membrane
0.39	GO:0045121	membrane raft
0.38	GO:0043005	neuron projection
0.38	GO:0005576	extracellular region
0.38	GO:0045202	synapse
0.38	GO:0030054	cell junction
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|R4GHW4|R4GHW4_CHICK
Uncharacterized protein
Search

PERP

0.97	PERP, TP53 apoptosis effector

0.50	GO:0097202	activation of cysteine-type endopeptidase activity
0.48	GO:0002934	desmosome organization
0.48	GO:0097186	amelogenesis
0.48	GO:0034113	heterotypic cell-cell adhesion
0.47	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.46	GO:0007219	Notch signaling pathway
0.40	GO:1902262	apoptotic process involved in blood vessel morphogenesis
0.39	GO:0009411	response to UV
0.38	GO:0042981	regulation of apoptotic process
0.35	GO:0070268	cornification

0.43	GO:0005794	Golgi apparatus
0.41	GO:0005887	integral component of plasma membrane
0.39	GO:0005739	mitochondrion
0.36	GO:0030057	desmosome

tr|R4GHW9|R4GHW9_CHICK
Erythroid protein 4.1
Search

EPB41

0.73	Erythrocyte membrane protein band 4.1

0.82	GO:0030866	cortical actin cytoskeleton organization
0.66	GO:1904778	positive regulation of protein localization to cell cortex
0.63	GO:0032092	positive regulation of protein binding
0.53	GO:0008360	regulation of cell shape
0.53	GO:0031032	actomyosin structure organization
0.37	GO:0006461	protein complex assembly

0.71	GO:0008092	cytoskeletal protein binding
0.62	GO:0047485	protein N-terminus binding
0.61	GO:0051219	phosphoprotein binding
0.61	GO:0005545	1-phosphatidylinositol binding
0.61	GO:0008022	protein C-terminus binding
0.60	GO:0005198	structural molecule activity

0.69	GO:0005856	cytoskeleton
0.61	GO:0099738	cell cortex region
0.55	GO:0030054	cell junction
0.52	GO:0005829	cytosol
0.47	GO:0043234	protein complex
0.46	GO:0005886	plasma membrane
0.39	GO:0014069	postsynaptic density
0.38	GO:0098562	cytoplasmic side of membrane

tr|R4GHX1|R4GHX1_CHICK
Uncharacterized protein
Search

0.55	MACRO domain-containing protein 2

0.87	GO:0051725	protein de-ADP-ribosylation
0.79	GO:0007420	brain development
0.71	GO:0042278	purine nucleoside metabolic process
0.65	GO:0006974	cellular response to DNA damage stimulus

0.75	GO:0019213	deacetylase activity
0.66	GO:0016798	hydrolase activity, acting on glycosyl bonds

0.78	GO:0005813	centrosome
0.73	GO:0005730	nucleolus

0.66

EC:3.2

GO:0016798

tr|R4GHY3|R4GHY3_CHICK
Uncharacterized protein
Search

LYPLAL1

0.97	Lysophospholipase like 1

0.49	GO:0002084	protein depalmitoylation
0.37	GO:0042997	negative regulation of Golgi to plasma membrane protein transport
0.32	GO:0055114	oxidation-reduction process

0.51	GO:0016787	hydrolase activity
0.40	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.48	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.51

GO:0016787

tr|R4GHY8|R4GHY8_CHICK
Uncharacterized protein
Search

CCDC92

0.97	Coiled-coil domain-containing protein 92

0.36

GO:0005515

protein binding

0.82	GO:0005814	centriole
0.75	GO:0005813	centrosome
0.68	GO:0005654	nucleoplasm

tr|R4GHZ2|R4GHZ2_CHICK
Uncharacterized protein
Search

DKK2

0.96	Dickkopf WNT signaling pathway inhibitor 2

0.79	GO:0030178	negative regulation of Wnt signaling pathway
0.67	GO:0007275	multicellular organism development
0.59	GO:0060828	regulation of canonical Wnt signaling pathway
0.56	GO:0030177	positive regulation of Wnt signaling pathway
0.48	GO:0009888	tissue development
0.47	GO:0061168	regulation of hair follicle placode formation
0.47	GO:0016055	Wnt signaling pathway
0.46	GO:0051799	negative regulation of hair follicle development
0.44	GO:1904711	regulation of Wnt-Frizzled-LRP5/6 complex assembly
0.43	GO:0042662	negative regulation of mesodermal cell fate specification

0.62	GO:0039706	co-receptor binding
0.42	GO:0048019	receptor antagonist activity
0.42	GO:0050750	low-density lipoprotein particle receptor binding
0.33	GO:0004252	serine-type endopeptidase activity

0.64	GO:0005576	extracellular region
0.36	GO:0005886	plasma membrane
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.33

GO:0004252

tr|R4GHZ8|R4GHZ8_CHICK
Uncharacterized protein
Search

S1PR1

0.95	Endothelial differentiation, sphingolipid G-protein-coupled receptor, 1

0.85	GO:0003376	sphingosine-1-phosphate signaling pathway
0.57	GO:0003245	cardiac muscle tissue growth involved in heart morphogenesis
0.55	GO:0001955	blood vessel maturation
0.55	GO:0072678	T cell migration
0.54	GO:0045124	regulation of bone resorption
0.54	GO:0061384	heart trabecula morphogenesis
0.54	GO:0030032	lamellipodium assembly
0.53	GO:0030500	regulation of bone mineralization
0.53	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.53	GO:0030595	leukocyte chemotaxis

0.86	GO:0038036	sphingosine-1-phosphate receptor activity
0.52	GO:0001664	G-protein coupled receptor binding
0.38	GO:0046625	sphingolipid binding
0.32	GO:0016491	oxidoreductase activity

0.51	GO:0009897	external side of plasma membrane
0.47	GO:0005654	nucleoplasm
0.46	GO:0031226	intrinsic component of plasma membrane
0.38	GO:0045121	membrane raft
0.37	GO:0005768	endosome
0.34	GO:0098590	plasma membrane region
0.30	GO:0016021	integral component of membrane

0.32

EC:1

GO:0016491

tr|R4GI08|R4GI08_CHICK
Uncharacterized protein
Search

EVA1A

0.90	Eva-1 homolog A

0.36	GO:0006915	apoptotic process
0.36	GO:0006914	autophagy
0.34	GO:0043687	post-translational protein modification

0.56

GO:0030246

carbohydrate binding

0.39	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0005886	plasma membrane
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0031984	organelle subcompartment
0.33	GO:0044444	cytoplasmic part
0.33	GO:0070013	intracellular organelle lumen
0.30	GO:0044425	membrane part

tr|R4GI10|R4GI10_CHICK
Uncharacterized protein
Search

MSRB3

0.70	Methionine-R-sulfoxide reductase B3, mitochondrial

0.76	GO:0030091	protein repair
0.70	GO:0006979	response to oxidative stress
0.53	GO:0055114	oxidation-reduction process

0.79	GO:0033743	peptide-methionine (R)-S-oxide reductase activity
0.44	GO:0008270	zinc ion binding
0.43	GO:0033745	L-methionine-(R)-S-oxide reductase activity

0.41	GO:0005783	endoplasmic reticulum
0.38	GO:0005739	mitochondrion

0.79	EC:1.8.4 EC:1.8.4.12	GO:0033743
0.79	KEGG:R07607	GO:0033743

tr|R4GI13|R4GI13_CHICK
Uncharacterized protein
Search

CPLX3

0.96	Complexin III

0.76	GO:0006836	neurotransmitter transport
0.62	GO:0046928	regulation of neurotransmitter secretion
0.55	GO:0030073	insulin secretion
0.53	GO:0017156	calcium ion regulated exocytosis
0.53	GO:0048489	synaptic vesicle transport
0.53	GO:0099504	synaptic vesicle cycle
0.53	GO:0099643	signal release from synapse
0.53	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.35	GO:0018108	peptidyl-tyrosine phosphorylation
0.32	GO:0007275	multicellular organism development

0.84	GO:0019905	syntaxin binding
0.51	GO:0005326	neurotransmitter transporter activity
0.35	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003677	DNA binding

0.56	GO:0045202	synapse
0.52	GO:0097458	neuron part
0.47	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.39	GO:0120038	plasma membrane bounded cell projection part
0.38	GO:0030054	cell junction
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.35

GO:0004715

tr|R4GI14|R4GI14_CHICK
Uncharacterized protein
Search

BCL10

0.97	Putative caspase activation and recruitment domain of b-cell lymphoma 10

0.84	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.78	GO:0006915	apoptotic process
0.74	GO:0042981	regulation of apoptotic process
0.62	GO:0045416	positive regulation of interleukin-8 biosynthetic process
0.61	GO:0006968	cellular defense response
0.61	GO:0032094	response to food
0.60	GO:0050852	T cell receptor signaling pathway
0.60	GO:0050856	regulation of T cell receptor signaling pathway
0.59	GO:0001843	neural tube closure
0.59	GO:0071260	cellular response to mechanical stimulus

0.62	GO:0043422	protein kinase B binding
0.61	GO:0051059	NF-kappaB binding
0.59	GO:0043621	protein self-association
0.59	GO:0002020	protease binding
0.58	GO:0008022	protein C-terminus binding
0.58	GO:0019209	kinase activator activity
0.56	GO:0031625	ubiquitin protein ligase binding
0.56	GO:0003713	transcription coactivator activity
0.53	GO:0042802	identical protein binding
0.36	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process

0.65	GO:0032449	CBM complex
0.61	GO:0042101	T cell receptor complex
0.60	GO:0046696	lipopolysaccharide receptor complex
0.59	GO:0001772	immunological synapse
0.58	GO:0005881	cytoplasmic microtubule
0.56	GO:0045121	membrane raft
0.56	GO:0048471	perinuclear region of cytoplasm
0.56	GO:0005764	lysosome
0.51	GO:0005829	cytosol
0.47	GO:0005634	nucleus

tr|R4GI22|R4GI22_CHICK
Guanylate cyclase
Search

NPR2

0.57	Guanylate cyclase

0.82	GO:0006182	cGMP biosynthetic process
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.62	GO:0007168	receptor guanylyl cyclase signaling pathway
0.59	GO:1900194	negative regulation of oocyte maturation
0.59	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.56	GO:0051447	negative regulation of meiotic cell cycle
0.55	GO:0060348	bone development
0.50	GO:0022414	reproductive process
0.46	GO:0060038	cardiac muscle cell proliferation

0.82	GO:0004383	guanylate cyclase activity
0.63	GO:0004672	protein kinase activity
0.63	GO:0016941	natriuretic peptide receptor activity
0.59	GO:0017046	peptide hormone binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0042802	identical protein binding
0.46	GO:0004016	adenylate cyclase activity

0.49	GO:0008074	guanylate cyclase complex, soluble
0.48	GO:0005887	integral component of plasma membrane
0.37	GO:0043235	receptor complex

0.82

EC:4.6.1.2

GO:0004383

tr|R4GI31|R4GI31_CHICK
Uncharacterized protein
Search

RND3

0.97	LOW QUALITY PROTEIN: rho-related GTP-binding protein RhoE

0.76	GO:0007264	small GTPase mediated signal transduction
0.37	GO:0048672	positive regulation of collateral sprouting
0.34	GO:0030036	actin cytoskeleton organization
0.34	GO:0007155	cell adhesion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0012505	endomembrane system
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|R4GI47|R4GI47_CHICK
Uncharacterized protein
Search

0.85	GO:0010457	centriole-centriole cohesion
0.71	GO:0033365	protein localization to organelle

0.78	GO:0030674	protein binding, bridging
0.76	GO:0019901	protein kinase binding
0.74	GO:0019904	protein domain specific binding
0.35	GO:0003779	actin binding

0.80	GO:0005814	centriole
0.76	GO:0005813	centrosome
0.68	GO:0005654	nucleoplasm
0.66	GO:0005829	cytosol
0.41	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part

tr|R4GI48|R4GI48_CHICK
Uncharacterized protein
Search

BG1

0.93	B-G antigen homologous

0.38	GO:1904622	negative regulation of actin-dependent ATPase activity
0.38	GO:1904616	regulation of actin binding
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.36	GO:0019903	protein phosphatase binding
0.36	GO:0003779	actin binding
0.32	GO:0046872	metal ion binding
0.31	GO:0003676	nucleic acid binding

0.38	GO:0031528	microvillus membrane
0.37	GO:0031526	brush border membrane
0.35	GO:0009986	cell surface
0.35	GO:0005887	integral component of plasma membrane
0.31	GO:0005622	intracellular

tr|R4GI53|R4GI53_CHICK
Uncharacterized protein
Search

ZCCHC24

0.97	Zinc finger CCHC domain-containing protein 24

0.33

GO:0010469

regulation of receptor activity

0.62	GO:0008270	zinc ion binding
0.50	GO:0003676	nucleic acid binding
0.33	GO:0008083	growth factor activity

0.33	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

tr|R4GI56|R4GI56_CHICK
Uncharacterized protein
Search

0.35	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.34	GO:0043066	negative regulation of apoptotic process

0.35

GO:0005031

tumor necrosis factor-activated receptor activity

0.34

GO:0005887

integral component of plasma membrane

tr|R4GI58|R4GI58_CHICK
Uncharacterized protein
Search

CTNNBIP1

0.94	beta-catenin-interacting protein 1

0.60	GO:0002528	regulation of vascular permeability involved in acute inflammatory response
0.58	GO:0072201	negative regulation of mesenchymal cell proliferation
0.58	GO:0045657	positive regulation of monocyte differentiation
0.58	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter
0.58	GO:0001658	branching involved in ureteric bud morphogenesis
0.56	GO:0045669	positive regulation of osteoblast differentiation
0.56	GO:0048662	negative regulation of smooth muscle cell proliferation
0.56	GO:0030178	negative regulation of Wnt signaling pathway
0.56	GO:0043392	negative regulation of DNA binding
0.55	GO:0032091	negative regulation of protein binding

0.84	GO:0008013	beta-catenin binding
0.58	GO:0070016	armadillo repeat domain binding
0.40	GO:0042988	X11-like protein binding
0.39	GO:0001540	amyloid-beta binding
0.39	GO:0019894	kinesin binding
0.38	GO:0005509	calcium ion binding
0.33	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0016301	kinase activity

0.58	GO:0030877	beta-catenin destruction complex
0.49	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.38	GO:0014069	postsynaptic density
0.38	GO:0045211	postsynaptic membrane
0.37	GO:0009986	cell surface
0.37	GO:0005615	extracellular space
0.34	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.34	GO:0070013	intracellular organelle lumen
0.30	GO:0016021	integral component of membrane

tr|R4GI61|R4GI61_CHICK
Uncharacterized protein
Search

DOLK

0.81	Dolichol kinase

0.84	GO:0043048	dolichyl monophosphate biosynthetic process
0.56	GO:0016310	phosphorylation
0.44	GO:0043413	macromolecule glycosylation
0.44	GO:0009101	glycoprotein biosynthetic process
0.40	GO:0006464	cellular protein modification process
0.35	GO:0006489	dolichyl diphosphate biosynthetic process

0.85	GO:0004168	dolichol kinase activity
0.33	GO:0005515	protein binding

0.53

GO:0030176

integral component of endoplasmic reticulum membrane

0.85

EC:2.7.1.108

GO:0004168

tr|R4GI62|R4GI62_CHICK
Uncharacterized protein
Search

tr|R4GI63|R4GI63_CHICK
Uncharacterized protein
Search

NHLRC4

0.88	NHL-repeat-containing protein 4

tr|R4GI64|R4GI64_CHICK
Uncharacterized protein
Search

SPG7

0.66	Spastic paraplegia 7 (pure and complicated autosomal recessive)

0.61	GO:0006508	proteolysis
0.56	GO:1902686	mitochondrial outer membrane permeabilization involved in programmed cell death
0.54	GO:0008089	anterograde axonal transport
0.35	GO:0006851	mitochondrial calcium ion transmembrane transport
0.34	GO:0043043	peptide biosynthetic process
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0030155	regulation of cell adhesion
0.34	GO:0007399	nervous system development
0.34	GO:0007155	cell adhesion
0.34	GO:0010467	gene expression

0.70	GO:0004222	metalloendopeptidase activity
0.61	GO:0008270	zinc ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0003735	structural constituent of ribosome
0.35	GO:0051082	unfolded protein binding
0.34	GO:0004176	ATP-dependent peptidase activity
0.34	GO:0008568	microtubule-severing ATPase activity

0.57	GO:0005757	mitochondrial permeability transition pore complex
0.56	GO:0005745	m-AAA complex
0.54	GO:1904115	axon cytoplasm
0.35	GO:0005840	ribosome

0.70

EC:3.4.24

GO:0004222

tr|R4GI67|R4GI67_CHICK
Uncharacterized protein
Search

MMGT1

0.97	LOW QUALITY PROTEIN: membrane magnesium transporter 1

0.45	GO:1903830	magnesium ion transmembrane transport
0.41	GO:0006824	cobalt ion transport
0.41	GO:0006825	copper ion transport
0.38	GO:1903874	ferrous iron transmembrane transport
0.38	GO:0071421	manganese ion transmembrane transport
0.38	GO:0035444	nickel cation transmembrane transport

0.45	GO:0015095	magnesium ion transmembrane transporter activity
0.41	GO:0015087	cobalt ion transmembrane transporter activity
0.38	GO:0015093	ferrous iron transmembrane transporter activity
0.38	GO:0005384	manganese ion transmembrane transporter activity
0.38	GO:0005375	copper ion transmembrane transporter activity
0.38	GO:0015099	nickel cation transmembrane transporter activity

0.60	GO:0072546	ER membrane protein complex
0.53	GO:0005769	early endosome
0.49	GO:0005794	Golgi apparatus
0.44	GO:0010008	endosome membrane
0.41	GO:0005886	plasma membrane

tr|R4GI69|R4GI69_CHICK
Uncharacterized protein
Search

AKAIN1

0.64	A-kinase anchor protein C18orf42 homolog

0.57

GO:0016310

phosphorylation

0.60

GO:0016301

kinase activity

tr|R4GI70|R4GI70_CHICK
Uncharacterized protein
Search

RGS7BP

0.97	Regulator of G protein signaling 7 binding protein a

0.68	GO:0007186	G-protein coupled receptor signaling pathway
0.49	GO:0009968	negative regulation of signal transduction
0.39	GO:0006956	complement activation

0.36

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.55	GO:0005886	plasma membrane
0.48	GO:0005737	cytoplasm
0.38	GO:0046930	pore complex

tr|R4GI71|R4GI71_CHICK
Uncharacterized protein
Search

0.37	Small integral membrane protein 29

0.30

GO:0044425

membrane part

tr|R4GI79|R4GI79_CHICK
Uncharacterized protein
Search

0.97	Winged helix transcription factor AmphiFoxE4

0.57	GO:0006355	regulation of transcription, DNA-templated
0.56	GO:0009887	animal organ morphogenesis
0.52	GO:1904888	cranial skeletal system development
0.52	GO:0060022	hard palate development
0.52	GO:0060465	pharynx development
0.51	GO:0009888	tissue development
0.51	GO:0030878	thyroid gland development
0.51	GO:0002088	lens development in camera-type eye
0.51	GO:0060023	soft palate development
0.50	GO:0048568	embryonic organ development

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.34	GO:0008301	DNA binding, bending
0.33	GO:0001012	RNA polymerase II regulatory region DNA binding
0.33	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.40	GO:0005667	transcription factor complex

tr|R4GI80|R4GI80_CHICK
Uncharacterized protein
Search

SYNPO

0.77	Synaptopodin

0.84	GO:0032233	positive regulation of actin filament bundle assembly
0.59	GO:1905355	spine apparatus assembly
0.56	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.55	GO:0008542	visual learning
0.55	GO:0098886	modification of dendritic spine
0.36	GO:0048738	cardiac muscle tissue development
0.36	GO:0007519	skeletal muscle tissue development

0.72	GO:0003779	actin binding
0.35	GO:0031005	filamin binding
0.35	GO:0051393	alpha-actinin binding
0.32	GO:0046872	metal ion binding
0.32	GO:0016787	hydrolase activity

0.59	GO:0097444	spine apparatus
0.53	GO:0015629	actin cytoskeleton
0.47	GO:0030018	Z disc
0.43	GO:0016607	nuclear speck
0.42	GO:0030054	cell junction
0.41	GO:0005829	cytosol
0.33	GO:0044430	cytoskeletal part
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

tr|R4GI82|R4GI82_CHICK
Uncharacterized protein
Search

AASDHPPT

0.96	L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

0.48	GO:0019878	lysine biosynthetic process via aminoadipic acid
0.42	GO:0006633	fatty acid biosynthetic process
0.34	GO:0015939	pantothenate metabolic process

0.78	GO:0008897	holo-[acyl-carrier-protein] synthase activity
0.64	GO:0000287	magnesium ion binding
0.33	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.36	GO:0070062	extracellular exosome
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.78

EC:2.7.8.7

GO:0008897

tr|R4GI83|R4GI83_CHICK
Uncharacterized protein
Search

tr|R4GI86|R4GI86_CHICK
Uncharacterized protein
Search

CAB39

0.94	Calcium-binding protein 39

0.85	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.80	GO:0032147	activation of protein kinase activity
0.79	GO:0018105	peptidyl-serine phosphorylation
0.77	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.64	GO:0023014	signal transduction by protein phosphorylation
0.61	GO:0035556	intracellular signal transduction
0.48	GO:0051291	protein heterooligomerization

0.82	GO:0043539	protein serine/threonine kinase activator activity
0.75	GO:0019900	kinase binding
0.69	GO:0004674	protein serine/threonine kinase activity
0.37	GO:0005509	calcium ion binding

0.44	GO:0005622	intracellular
0.41	GO:0070062	extracellular exosome
0.40	GO:0043234	protein complex

0.69

GO:0004674

tr|R4GI90|R4GI90_CHICK
Uncharacterized protein
Search

0.97

Meleagrin

0.79	GO:0045087	innate immune response
0.41	GO:0050830	defense response to Gram-positive bacterium
0.41	GO:0050829	defense response to Gram-negative bacterium

0.66	GO:0005576	extracellular region
0.30	GO:0005623	cell

tr|R4GI92|R4GI92_CHICK
Uncharacterized protein
Search

FOXO3

0.91	Forkhead box protein O1-A

0.58	GO:0001544	initiation of primordial ovarian follicle growth
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0001547	antral ovarian follicle growth
0.56	GO:0001542	ovulation from ovarian follicle
0.56	GO:0010468	regulation of gene expression
0.55	GO:0001556	oocyte maturation
0.55	GO:0006351	transcription, DNA-templated
0.55	GO:0045648	positive regulation of erythrocyte differentiation
0.55	GO:0043523	regulation of neuron apoptotic process

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0031490	chromatin DNA binding
0.53	GO:0008013	beta-catenin binding
0.53	GO:0001047	core promoter binding
0.51	GO:0019901	protein kinase binding
0.39	GO:0001221	transcription cofactor binding

0.61	GO:0005634	nucleus
0.47	GO:0005829	cytosol
0.46	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.35	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

tr|R4GI94|R4GI94_CHICK
Uncharacterized protein
Search

CLEC18A

0.85	C-type lectin domain family 18 member A

0.37	GO:0060536	cartilage morphogenesis
0.37	GO:0060325	face morphogenesis
0.37	GO:0048703	embryonic viscerocranium morphogenesis
0.37	GO:0060021	palate development
0.34	GO:0007338	single fertilization
0.33	GO:0071805	potassium ion transmembrane transport

0.56	GO:0030246	carbohydrate binding
0.33	GO:0005267	potassium channel activity

0.57	GO:0005576	extracellular region
0.36	GO:0016529	sarcoplasmic reticulum
0.36	GO:0031410	cytoplasmic vesicle
0.35	GO:0005794	Golgi apparatus
0.34	GO:0097223	sperm part
0.34	GO:0045121	membrane raft
0.34	GO:0031225	anchored component of membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|R4GI98|R4GI98_CHICK
Uncharacterized protein
Search

NHLH1

0.97	Nescient helix-loop-helix 1

0.54	GO:0006366	transcription by RNA polymerase II
0.54	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:0007617	mating behavior
0.49	GO:0042698	ovulation cycle
0.36	GO:0030154	cell differentiation
0.36	GO:0007275	multicellular organism development
0.34	GO:0051091	positive regulation of DNA binding transcription factor activity

0.68	GO:0046983	protein dimerization activity
0.57	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.56	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.49	GO:0001102	RNA polymerase II activating transcription factor binding
0.47	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0000987	proximal promoter sequence-specific DNA binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005634	nucleus
0.33	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

tr|R4GIA2|R4GIA2_CHICK
Uncharacterized protein
Search

GPN2

0.93	G patch domain containing 3

0.85	GO:1990022	RNA polymerase III complex localization to nucleus
0.85	GO:0044376	RNA polymerase II complex import to nucleus
0.39	GO:0000413	protein peptidyl-prolyl isomerization
0.37	GO:0006457	protein folding
0.37	GO:0006481	C-terminal protein methylation
0.35	GO:0008299	isoprenoid biosynthetic process

0.65	GO:0003924	GTPase activity
0.52	GO:0032550	purine ribonucleoside binding
0.52	GO:0019001	guanyl nucleotide binding
0.44	GO:0032555	purine ribonucleotide binding
0.44	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.37	GO:0004671	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
0.34	GO:0016779	nucleotidyltransferase activity

0.48	GO:0005737	cytoplasm
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment
0.33	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.39	EC:5.2.1.8	GO:0003755
0.37	KEGG:R04496	GO:0004671

tr|R4GIA4|R4GIA4_CHICK
Olfactory receptor
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|R4GIA5|R4GIA5_CHICK
Uncharacterized protein
Search

RERG

0.89	RAS like estrogen regulated growth inhibitor

0.61	GO:0007165	signal transduction
0.55	GO:0030308	negative regulation of cell growth
0.52	GO:0008285	negative regulation of cell proliferation
0.50	GO:0009725	response to hormone
0.35	GO:1901214	regulation of neuron death
0.35	GO:0030335	positive regulation of cell migration
0.33	GO:0006278	RNA-dependent DNA biosynthetic process

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0030331	estrogen receptor binding
0.33	GO:0003964	RNA-directed DNA polymerase activity
0.33	GO:0004767	sphingomyelin phosphodiesterase activity
0.32	GO:0003676	nucleic acid binding

0.48	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33	EC:2.7.7.49	GO:0003964
0.33	KEGG:R02541	GO:0004767

tr|R4GIA8|R4GIA8_CHICK
Uncharacterized protein
Search

PKIB

0.95	cAMP-dependent protein kinase inhibitor beta

0.82	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.50	GO:1904355	positive regulation of telomere capping
0.49	GO:0016310	phosphorylation
0.49	GO:0051973	positive regulation of telomerase activity
0.49	GO:0032212	positive regulation of telomere maintenance via telomerase
0.47	GO:2000479	regulation of cAMP-dependent protein kinase activity

0.86	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.51	GO:0016301	kinase activity
0.34	GO:0008289	lipid binding

0.39	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|R4GIB0|R4GIB0_CHICK
Uncharacterized protein
Search

MANSC4

0.97	MANSC domain-containing protein 4

0.30

GO:0044425

membrane part

tr|R4GIB4|R4GIB4_CHICK
Uncharacterized protein
Search

JMJD7

0.73	JmjC domain-containing protein 7

0.74	GO:0009395	phospholipid catabolic process
0.39	GO:0045454	cell redox homeostasis

0.78	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.78	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.75	GO:0004623	phospholipase A2 activity
0.51	GO:0046872	metal ion binding
0.38	GO:0005515	protein binding

0.46

GO:0005737

cytoplasm

0.75

GO:0004623

tr|R4GIB7|R4GIB7_CHICK
Uncharacterized protein
Search

SAAL1

0.84	Serum amyloid A like 1

0.40	GO:0009072	aromatic amino acid family metabolic process
0.36	GO:0055114	oxidation-reduction process

0.44	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
0.39	GO:0005506	iron ion binding
0.35	GO:0046982	protein heterodimerization activity
0.33	GO:0003677	DNA binding

0.66	GO:0005615	extracellular space
0.45	GO:0005581	collagen trimer
0.41	GO:0005634	nucleus
0.35	GO:0000786	nucleosome

0.44

EC:1.14.16

GO:0016714

tr|R4GIC1|R4GIC1_CHICK
Uncharacterized protein
Search

0.64	Solute carrier family 35 member E4

0.30

GO:0044425

membrane part

tr|R4GIC2|R4GIC2_CHICK
Uncharacterized protein
Search

GUCA2A

0.95	Preprorenoguanylin

0.86	GO:0031284	positive regulation of guanylate cyclase activity
0.39	GO:0045776	negative regulation of blood pressure
0.39	GO:0007588	excretion
0.39	GO:0007589	body fluid secretion
0.38	GO:0006182	cGMP biosynthetic process
0.36	GO:0007586	digestion
0.35	GO:0010469	regulation of receptor activity

0.86	GO:0010853	cyclase activator activity
0.86	GO:0030249	guanylate cyclase regulator activity
0.75	GO:0008047	enzyme activator activity
0.36	GO:0005179	hormone activity

0.66	GO:0005576	extracellular region
0.38	GO:0001750	photoreceptor outer segment
0.35	GO:0031982	vesicle

tr|R4GIC8|R4GIC8_CHICK
Uncharacterized protein
Search

ARHGAP11A

0.94	Rho GTPase activating protein N/AflII-2

0.60	GO:0007165	signal transduction
0.42	GO:0043547	positive regulation of GTPase activity
0.35	GO:0051056	regulation of small GTPase mediated signal transduction
0.33	GO:0021987	cerebral cortex development

0.43

GO:0005096

GTPase activator activity

0.42	GO:0030141	secretory granule
0.35	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|R4GIC9|R4GIC9_CHICK
Uncharacterized protein
Search

0.38	GO:0007229	integrin-mediated signaling pathway
0.35	GO:0006508	proteolysis

0.37	GO:0004222	metalloendopeptidase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0016757	transferase activity, transferring glycosyl groups

0.36	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.37

EC:3.4.24

GO:0004222

tr|R4GIE5|R4GIE5_CHICK
Uncharacterized protein
Search

SELENOM

0.97	Selenoprotein M

0.87	GO:0035934	corticosterone secretion
0.86	GO:0010269	response to selenium ion
0.84	GO:0060612	adipose tissue development
0.82	GO:0035264	multicellular organism growth
0.73	GO:0042445	hormone metabolic process

0.42

GO:0005515

protein binding

0.70	GO:0005783	endoplasmic reticulum
0.69	GO:0005794	Golgi apparatus
0.54	GO:0048471	perinuclear region of cytoplasm

tr|R4GIE6|R4GIE6_CHICK
Uncharacterized protein
Search

TFAP4

0.88	Transcription factor AP-4 (Activating enhancer binding protein 4)

0.60	GO:0043922	negative regulation by host of viral transcription
0.60	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
0.59	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.59	GO:0043923	positive regulation by host of viral transcription
0.58	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity
0.58	GO:0071549	cellular response to dexamethasone stimulus
0.58	GO:0071157	negative regulation of cell cycle arrest
0.57	GO:0043392	negative regulation of DNA binding
0.54	GO:0008285	negative regulation of cell proliferation
0.54	GO:1901990	regulation of mitotic cell cycle phase transition

0.68	GO:0046983	protein dimerization activity
0.58	GO:0070888	E-box binding
0.57	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.57	GO:0042826	histone deacetylase binding
0.55	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0042802	identical protein binding
0.36	GO:0003713	transcription coactivator activity

0.54	GO:0017053	transcriptional repressor complex
0.47	GO:0005634	nucleus
0.45	GO:0005739	mitochondrion

tr|R4GIF1|R4GIF1_CHICK
Uncharacterized protein
Search

ANKRD9

0.97	LOW QUALITY PROTEIN: ankyrin repeat domain-containing protein 9

0.53

GO:0043687

post-translational protein modification

0.38

GO:0016787

hydrolase activity

0.47

GO:0005829

cytosol

0.38

GO:0016787

tr|R4GIF2|R4GIF2_CHICK
Uncharacterized protein
Search

0.92	TIR-domain containing adaptor inducing interferon-beta

0.79	GO:0045087	innate immune response
0.61	GO:0007165	signal transduction
0.50	GO:0043330	response to exogenous dsRNA
0.49	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.47	GO:0002218	activation of innate immune response
0.46	GO:0140052	cellular response to oxidised low-density lipoprotein particle stimulus
0.45	GO:0045359	positive regulation of interferon-beta biosynthetic process
0.45	GO:0045080	positive regulation of chemokine biosynthetic process
0.45	GO:0002281	macrophage activation involved in immune response
0.45	GO:1900017	positive regulation of cytokine production involved in inflammatory response

0.64	GO:0004871	signal transducer activity
0.47	GO:0019901	protein kinase binding
0.33	GO:0008236	serine-type peptidase activity

0.52	GO:0097342	ripoptosome
0.36	GO:0005776	autophagosome
0.35	GO:0031410	cytoplasmic vesicle
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0012505	endomembrane system
0.32	GO:0044446	intracellular organelle part

tr|R4GIF5|R4GIF5_CHICK
Uncharacterized protein
Search

tr|R4GIF7|R4GIF7_CHICK
Uncharacterized protein
Search

0.11	LOW QUALITY PROTEIN: probable tubulin polyglutamylase TTLL2

0.60	GO:0006464	cellular protein modification process
0.39	GO:0006364	rRNA processing

0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0016874	ligase activity

0.41

GO:0032040

small-subunit processome

0.41

GO:0016874

tr|R4GIF9|R4GIF9_CHICK
Keratin
Search

0.83	Feather beta keratin

0.71

GO:0007010

cytoskeleton organization

0.77

GO:0005200

structural constituent of cytoskeleton

0.79

GO:0005882

intermediate filament

tr|R4GIG1|R4GIG1_CHICK
Uncharacterized protein
Search

0.72	Fast myosin heavy chain HCIII

0.74	GO:0007018	microtubule-based movement
0.52	GO:0006936	muscle contraction
0.50	GO:0014823	response to activity
0.49	GO:0033275	actin-myosin filament sliding
0.47	GO:0050881	musculoskeletal movement
0.40	GO:0046034	ATP metabolic process
0.38	GO:0001778	plasma membrane repair
0.38	GO:0031034	myosin filament assembly
0.35	GO:0035994	response to muscle stretch
0.35	GO:0009629	response to gravity

0.78	GO:0051015	actin filament binding
0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0000146	microfilament motor activity
0.45	GO:0005516	calmodulin binding
0.41	GO:0016887	ATPase activity
0.38	GO:0003725	double-stranded RNA binding

0.77	GO:0016459	myosin complex
0.55	GO:0043292	contractile fiber
0.46	GO:0036464	cytoplasmic ribonucleoprotein granule
0.45	GO:0014704	intercalated disc
0.38	GO:0005826	actomyosin contractile ring
0.36	GO:0005794	Golgi apparatus
0.35	GO:0005829	cytosol

0.41

EC:3.6.1.3

GO:0016887

tr|R4GIG3|R4GIG3_CHICK
Uncharacterized protein
Search

PNMT

0.94	Phenylethanolamine N-methyltransferase

0.63	GO:0032259	methylation
0.43	GO:0042418	epinephrine biosynthetic process
0.38	GO:0031100	animal organ regeneration
0.38	GO:0010243	response to organonitrogen compound
0.37	GO:0042493	response to drug
0.36	GO:0035900	response to isolation stress
0.36	GO:0035902	response to immobilization stress
0.36	GO:0045472	response to ether
0.36	GO:0042415	norepinephrine metabolic process
0.35	GO:0030325	adrenal gland development

0.63

GO:0008168

methyltransferase activity

0.44	GO:0005829	cytosol
0.36	GO:0043196	varicosity
0.35	GO:0043204	perikaryon
0.35	GO:0043195	terminal bouton
0.35	GO:0030425	dendrite
0.34	GO:0005634	nucleus

0.63

GO:0008168

tr|R4GIG4|R4GIG4_CHICK
Uncharacterized protein
Search

SH2D1B

0.97	SH2 domain-containing protein 1B

0.57	GO:0046580	negative regulation of Ras protein signal transduction
0.56	GO:0043547	positive regulation of GTPase activity
0.50	GO:0018108	peptidyl-tyrosine phosphorylation
0.50	GO:0001953	negative regulation of cell-matrix adhesion
0.48	GO:0007165	signal transduction
0.47	GO:0048514	blood vessel morphogenesis
0.47	GO:0032956	regulation of actin cytoskeleton organization
0.46	GO:0043066	negative regulation of apoptotic process
0.46	GO:0032271	regulation of protein polymerization
0.46	GO:1902903	regulation of supramolecular fiber organization

0.57	GO:0005096	GTPase activator activity
0.52	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.50	GO:0001784	phosphotyrosine residue binding
0.46	GO:0005102	receptor binding
0.45	GO:0019899	enzyme binding
0.41	GO:0030554	adenyl nucleotide binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0032555	purine ribonucleotide binding
0.41	GO:0008144	drug binding
0.39	GO:0030674	protein binding, bridging

0.49	GO:0001726	ruffle
0.43	GO:0009898	cytoplasmic side of plasma membrane
0.42	GO:0005622	intracellular
0.39	GO:0031226	intrinsic component of plasma membrane
0.38	GO:0019897	extrinsic component of plasma membrane
0.37	GO:0031256	leading edge membrane
0.37	GO:0031253	cell projection membrane
0.35	GO:0031090	organelle membrane
0.35	GO:0031974	membrane-enclosed lumen
0.35	GO:0031975	envelope

0.52

GO:0004715

tr|R4GIH6|R4GIH6_CHICK
Uncharacterized protein
Search

SLC38A3

0.95	Sodium-coupled neutral amino acid transporter 3

0.59	GO:0006867	asparagine transport
0.58	GO:0006868	glutamine transport
0.57	GO:0015817	histidine transport
0.57	GO:0089709	L-histidine transmembrane transport
0.56	GO:0015808	L-alanine transport
0.56	GO:0061402	positive regulation of transcription from RNA polymerase II promoter in response to acidic pH
0.56	GO:0051365	cellular response to potassium ion starvation
0.40	GO:2000487	positive regulation of glutamine transport
0.39	GO:0015816	glycine transport
0.38	GO:0007565	female pregnancy

0.60	GO:0015182	L-asparagine transmembrane transporter activity
0.58	GO:0015186	L-glutamine transmembrane transporter activity
0.57	GO:0005290	L-histidine transmembrane transporter activity
0.56	GO:0015180	L-alanine transmembrane transporter activity
0.40	GO:0015187	glycine transmembrane transporter activity
0.36	GO:0015293	symporter activity
0.36	GO:0015297	antiporter activity

0.48	GO:0005887	integral component of plasma membrane
0.37	GO:0016323	basolateral plasma membrane

tr|R4GII2|R4GII2_CHICK
Uncharacterized protein
Search

TMEM207

0.97	Transmembrane protein 207

0.30

GO:0044425

membrane part

tr|R4GII3|R4GII3_CHICK
5' exonuclease Apollo
Search

DCLRE1B

0.97	5' exonuclease Apollo

0.67	GO:0031848	protection from non-homologous end joining at telomere
0.67	GO:0031860	telomeric 3' overhang formation
0.66	GO:0031627	telomeric loop formation
0.63	GO:0036297	interstrand cross-link repair
0.62	GO:0010833	telomere maintenance via telomere lengthening
0.60	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.59	GO:0000075	cell cycle checkpoint
0.52	GO:0006303	double-strand break repair via nonhomologous end joining
0.39	GO:0006468	protein phosphorylation
0.34	GO:0006289	nucleotide-excision repair

0.65	GO:0004527	exonuclease activity
0.55	GO:0042803	protein homodimerization activity
0.53	GO:0044877	macromolecular complex binding
0.49	GO:0003684	damaged DNA binding
0.48	GO:0004536	deoxyribonuclease activity
0.39	GO:0004672	protein kinase activity
0.37	GO:0005524	ATP binding
0.35	GO:0043047	single-stranded telomeric DNA binding
0.33	GO:0005096	GTPase activator activity
0.33	GO:0004519	endonuclease activity

0.62	GO:0000784	nuclear chromosome, telomeric region
0.58	GO:0005813	centrosome
0.56	GO:0016604	nuclear body
0.34	GO:0005737	cytoplasm
0.34	GO:0070419	nonhomologous end joining complex
0.32	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016874

tr|R4GII9|R4GII9_CHICK
Uncharacterized protein
Search

0.43	Low-specificity L-threonine aldolase

0.60	GO:0006520	cellular amino acid metabolic process
0.44	GO:0042136	neurotransmitter biosynthetic process
0.41	GO:0046395	carboxylic acid catabolic process
0.41	GO:1901565	organonitrogen compound catabolic process
0.39	GO:0046394	carboxylic acid biosynthetic process
0.39	GO:0017144	drug metabolic process
0.37	GO:1901566	organonitrogen compound biosynthetic process
0.32	GO:0006468	protein phosphorylation

0.62	GO:0016829	lyase activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0016874	ligase activity
0.32	GO:0016740	transferase activity
0.32	GO:0140096	catalytic activity, acting on a protein
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005829	cytosol
0.32	GO:0019013	viral nucleocapsid
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.62

EC:4

GO:0016829

tr|R4GIJ8|R4GIJ8_CHICK
Adenosine receptor A3
Search

ADORA3

0.81	Adenosine receptor A3

0.85	GO:0001973	adenosine receptor signaling pathway
0.48	GO:0030336	negative regulation of cell migration
0.47	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.45	GO:0008285	negative regulation of cell proliferation
0.42	GO:0070255	regulation of mucus secretion
0.40	GO:1900453	negative regulation of long term synaptic depression
0.40	GO:0002685	regulation of leukocyte migration
0.40	GO:0003093	regulation of glomerular filtration
0.40	GO:0050727	regulation of inflammatory response
0.40	GO:0051930	regulation of sensory perception of pain

0.85

GO:0001609

G-protein coupled adenosine receptor activity

0.55	GO:0005886	plasma membrane
0.39	GO:0043197	dendritic spine
0.36	GO:0042629	mast cell granule
0.34	GO:0098793	presynapse
0.30	GO:0016021	integral component of membrane

tr|R4GIL1|R4GIL1_CHICK
Paired mesoderm homeobox protein 2
Search

PRRX2

0.93	Paired mesoderm homeobox protein 2

0.67	GO:0007275	multicellular organism development
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:1904888	cranial skeletal system development
0.53	GO:0002053	positive regulation of mesenchymal cell proliferation
0.52	GO:0045880	positive regulation of smoothened signaling pathway
0.51	GO:0097150	neuronal stem cell population maintenance
0.50	GO:0061448	connective tissue development
0.50	GO:0060021	palate development

0.64	GO:0043565	sequence-specific DNA binding
0.53	GO:0071837	HMG box domain binding
0.50	GO:0001105	RNA polymerase II transcription coactivator activity
0.50	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003690	double-stranded DNA binding
0.37	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.44	GO:0005829	cytosol
0.44	GO:0043233	organelle lumen
0.40	GO:0044446	intracellular organelle part

tr|R4GIL3|R4GIL3_CHICK
Uncharacterized protein
Search

0.76	Heparan-sulfate 6-O-sulfotransferase

0.55	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification
0.43	GO:0048666	neuron development
0.41	GO:0048286	lung alveolus development
0.41	GO:0060716	labyrinthine layer blood vessel development
0.40	GO:0001525	angiogenesis
0.33	GO:0006024	glycosaminoglycan biosynthetic process

0.78	GO:0008146	sulfotransferase activity
0.35	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding
0.34	GO:0070492	oligosaccharide binding

0.33	GO:0000139	Golgi membrane
0.33	GO:0005887	integral component of plasma membrane

0.78

EC:2.8.2

GO:0008146

tr|R4GIL4|R4GIL4_CHICK
Uncharacterized protein
Search

0.10	cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Fragment)

0.58	GO:0007165	signal transduction
0.56	GO:0032743	positive regulation of interleukin-2 production
0.56	GO:0006198	cAMP catabolic process
0.56	GO:0032729	positive regulation of interferon-gamma production
0.55	GO:0001780	neutrophil homeostasis
0.54	GO:0030593	neutrophil chemotaxis
0.53	GO:0002253	activation of immune response
0.53	GO:0071222	cellular response to lipopolysaccharide
0.52	GO:0035690	cellular response to drug
0.43	GO:0006939	smooth muscle contraction

0.75	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.56	GO:0030552	cAMP binding
0.52	GO:0043015	gamma-tubulin binding
0.51	GO:0046872	metal ion binding
0.40	GO:0044325	ion channel binding

0.54	GO:0060076	excitatory synapse
0.53	GO:0043197	dendritic spine
0.52	GO:0014069	postsynaptic density
0.52	GO:0000930	gamma-tubulin complex
0.52	GO:0008021	synaptic vesicle
0.50	GO:0005813	centrosome
0.47	GO:0005829	cytosol
0.41	GO:0071944	cell periphery
0.40	GO:0030018	Z disc
0.39	GO:0034704	calcium channel complex

0.75

EC:3.1.4.17

GO:0004114

tr|R4GIL5|R4GIL5_CHICK
Metalloproteinase inhibitor 2
Search

TIMP2

0.89	Tissue inhibitor of metalloproteinase

0.75	GO:0010951	negative regulation of endopeptidase activity
0.49	GO:1905049	negative regulation of metallopeptidase activity
0.47	GO:0051045	negative regulation of membrane protein ectodomain proteolysis
0.44	GO:0034097	response to cytokine
0.43	GO:0009725	response to hormone
0.41	GO:0032487	regulation of Rap protein signal transduction
0.41	GO:0030814	regulation of cAMP metabolic process
0.40	GO:0051349	positive regulation of lyase activity
0.40	GO:0031281	positive regulation of cyclase activity
0.40	GO:0045664	regulation of neuron differentiation

0.85	GO:0008191	metalloendopeptidase inhibitor activity
0.50	GO:0002020	protease binding
0.41	GO:0005178	integrin binding
0.41	GO:0008270	zinc ion binding
0.40	GO:0098770	FBXO family protein binding
0.36	GO:0008047	enzyme activator activity
0.35	GO:0008237	metallopeptidase activity

0.65	GO:0005576	extracellular region
0.39	GO:0030426	growth cone
0.39	GO:0009986	cell surface
0.39	GO:0043025	neuronal cell body
0.37	GO:1904724	tertiary granule lumen
0.37	GO:0035580	specific granule lumen
0.36	GO:1904813	ficolin-1-rich granule lumen
0.33	GO:0005634	nucleus

tr|R4GIM6|R4GIM6_CHICK
Uncharacterized protein
Search

TMEM165

0.50	Transmembrane protein 165

0.59	GO:0032472	Golgi calcium ion transport
0.58	GO:0035751	regulation of lysosomal lumen pH
0.56	GO:0006487	protein N-linked glycosylation
0.53	GO:0006874	cellular calcium ion homeostasis
0.45	GO:0060536	cartilage morphogenesis
0.44	GO:0048703	embryonic viscerocranium morphogenesis
0.44	GO:0002062	chondrocyte differentiation
0.44	GO:0001649	osteoblast differentiation
0.33	GO:0006629	lipid metabolic process
0.32	GO:0055114	oxidation-reduction process

0.33

GO:0016627

oxidoreductase activity, acting on the CH-CH group of donors

0.56	GO:0032588	trans-Golgi network membrane
0.54	GO:0005765	lysosomal membrane
0.52	GO:0010008	endosome membrane
0.37	GO:0005770	late endosome
0.37	GO:0005769	early endosome
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:1.3

GO:0016627

tr|R4GIN1|R4GIN1_CHICK
Uncharacterized protein
Search

0.86	Interferon type B

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.57	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.57	GO:0002323	natural killer cell activation involved in immune response
0.56	GO:0042100	B cell proliferation
0.56	GO:0002286	T cell activation involved in immune response
0.55	GO:0043330	response to exogenous dsRNA
0.55	GO:0030183	B cell differentiation
0.54	GO:0002250	adaptive immune response
0.53	GO:0006959	humoral immune response

0.81	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.50	GO:0032403	protein complex binding

0.73

GO:0005615

extracellular space

tr|R4GIN8|R4GIN8_CHICK
Uncharacterized protein
Search

PRKACB

0.94	cAMP-dependent protein kinase catalytic subunit beta

0.60	GO:0006468	protein phosphorylation
0.52	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.50	GO:0001843	neural tube closure
0.50	GO:0070613	regulation of protein processing
0.37	GO:0097338	response to clozapine
0.36	GO:0051447	negative regulation of meiotic cell cycle
0.34	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway

0.66	GO:0004674	protein serine/threonine kinase activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0060089	molecular transducer activity
0.43	GO:0000287	magnesium ion binding
0.35	GO:0034237	protein kinase A regulatory subunit binding

0.50	GO:0097546	ciliary base
0.50	GO:0045171	intercellular bridge
0.47	GO:0005813	centrosome
0.44	GO:0005829	cytosol
0.36	GO:0005952	cAMP-dependent protein kinase complex
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005634	nucleus
0.34	GO:0070062	extracellular exosome
0.34	GO:0005886	plasma membrane

0.66

GO:0004674

tr|R4GIN9|R4GIN9_CHICK
Uncharacterized protein
Search

LRTM2

0.97	Leucine-rich repeat and transmembrane domain-containing protein 2

0.58	GO:0051965	positive regulation of synapse assembly
0.48	GO:0046426	negative regulation of JAK-STAT cascade
0.46	GO:0006469	negative regulation of protein kinase activity
0.46	GO:0019221	cytokine-mediated signaling pathway
0.38	GO:0007409	axonogenesis

0.47

GO:0004860

protein kinase inhibitor activity

0.37	GO:0005578	proteinaceous extracellular matrix
0.37	GO:0005615	extracellular space
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|R4GIP1|R4GIP1_CHICK
Uncharacterized protein
Search

TMEM178B

0.92	Transmembrane protein 178

0.30

GO:0044425

membrane part

tr|R4GIP3|R4GIP3_CHICK
Uncharacterized protein
Search

ATXN1L

0.80	Brother of ataxin-1

0.63	GO:1902035	positive regulation of hematopoietic stem cell proliferation
0.60	GO:0048286	lung alveolus development
0.60	GO:0035176	social behavior
0.59	GO:0007613	memory
0.58	GO:0007612	learning
0.56	GO:0030198	extracellular matrix organization
0.56	GO:0007420	brain development
0.55	GO:0000122	negative regulation of transcription by RNA polymerase II
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0051168	nuclear export

0.59	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.34	GO:0003677	DNA binding

0.53	GO:0005730	nucleolus
0.51	GO:0005654	nucleoplasm
0.37	GO:0030425	dendrite
0.35	GO:0042405	nuclear inclusion body
0.34	GO:0016363	nuclear matrix
0.34	GO:0005737	cytoplasm
0.32	GO:0043234	protein complex
0.30	GO:0016020	membrane

tr|R4GIQ0|R4GIQ0_CHICK
Uncharacterized protein
Search

CCNO

0.97	Novel protein containing a Cyclin, N-terminal domain

0.64	GO:1903251	multi-ciliated epithelial cell differentiation
0.59	GO:0060271	cilium assembly
0.55	GO:0000278	mitotic cell cycle
0.54	GO:0006284	base-excision repair
0.44	GO:0051726	regulation of cell cycle
0.39	GO:0051301	cell division
0.38	GO:0042493	response to drug
0.35	GO:0006275	regulation of DNA replication
0.35	GO:0010332	response to gamma radiation
0.34	GO:0001558	regulation of cell growth

0.58	GO:0097506	deaminated base DNA N-glycosylase activity
0.34	GO:0004386	helicase activity
0.34	GO:0005515	protein binding
0.33	GO:0017110	nucleoside-diphosphatase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0005509	calcium ion binding

0.60	GO:0005634	nucleus
0.51	GO:0031974	membrane-enclosed lumen
0.46	GO:0044446	intracellular organelle part
0.41	GO:0005737	cytoplasm

0.33

EC:3.6.1.6

GO:0017110

tr|R4GIQ1|R4GIQ1_CHICK
Voltage-dependent calcium channel gamma subunit
Search

CACNG4

0.46	Multifunctional fusion protein (Fragment)

0.76	GO:0034765	regulation of ion transmembrane transport
0.75	GO:0070588	calcium ion transmembrane transport
0.58	GO:1900449	regulation of glutamate receptor signaling pathway
0.58	GO:0099601	regulation of neurotransmitter receptor activity
0.57	GO:0019226	transmission of nerve impulse
0.55	GO:0022898	regulation of transmembrane transporter activity
0.41	GO:0098953	receptor diffusion trapping
0.41	GO:0098943	neurotransmitter receptor transport, postsynaptic endosome to lysosome
0.41	GO:0099590	neurotransmitter receptor internalization
0.40	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels

0.79	GO:0005245	voltage-gated calcium channel activity
0.45	GO:0016247	channel regulator activity
0.34	GO:0035255	ionotropic glutamate receptor binding

0.78	GO:0005891	voltage-gated calcium channel complex
0.58	GO:0032281	AMPA glutamate receptor complex
0.51	GO:0036477	somatodendritic compartment
0.40	GO:0099634	postsynaptic specialization membrane
0.34	GO:0014069	postsynaptic density
0.33	GO:0005622	intracellular

tr|R4GIQ2|R4GIQ2_CHICK
Uncharacterized protein
Search

RPL21

0.71	Ribosomal protein L21

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.35	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.34	GO:0016072	rRNA metabolic process
0.34	GO:0042254	ribosome biogenesis

0.63	GO:0003735	structural constituent of ribosome
0.35	GO:0005515	protein binding
0.34	GO:0003723	RNA binding
0.33	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.42	GO:0044445	cytosolic part
0.38	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

GO:0016787

tr|R4GIQ3|R4GIQ3_CHICK
Keratin
Search

0.74	Claw keratin

0.69

GO:0007010

cytoskeleton organization

0.75

GO:0005200

structural constituent of cytoskeleton

0.77	GO:0005882	intermediate filament
0.30	GO:0031224	intrinsic component of membrane

tr|R4GIQ5|R4GIQ5_CHICK
Uncharacterized protein
Search

DUSP14

0.94	Dual-specificity protein phosphatase 6

0.82	GO:0000188	inactivation of MAPK activity
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.33	GO:0006626	protein targeting to mitochondrion
0.33	GO:0006612	protein targeting to membrane

0.83	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.33	GO:0003677	DNA binding

0.35	GO:0005634	nucleus
0.34	GO:0031314	extrinsic component of mitochondrial inner membrane
0.33	GO:0005758	mitochondrial intermembrane space
0.33	GO:0005759	mitochondrial matrix

0.83

EC:3.1.3

GO:0017017

tr|R4GIR0|R4GIR0_CHICK
Fibroblast growth factor
Search

FGF23

0.64	Fibroblast growth factor

0.84	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.64	GO:0042369	vitamin D catabolic process
0.64	GO:0010979	regulation of vitamin D 24-hydroxylase activity
0.62	GO:0010966	regulation of phosphate transport
0.62	GO:0030502	negative regulation of bone mineralization
0.61	GO:0045668	negative regulation of osteoblast differentiation
0.60	GO:0051353	positive regulation of oxidoreductase activity
0.59	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.56	GO:0072506	trivalent inorganic anion homeostasis

0.85	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0004713	protein tyrosine kinase activity

0.66	GO:0005576	extracellular region
0.38	GO:0005622	intracellular
0.34	GO:0012505	endomembrane system
0.34	GO:0043233	organelle lumen
0.33	GO:0043227	membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

tr|R4GIR8|R4GIR8_CHICK
Gap junction protein
Search

GJB3

0.64	Gap junction beta-3 protein (Fragment)

0.59	GO:0007154	cell communication
0.50	GO:0001890	placenta development
0.40	GO:0001701	in utero embryonic development
0.38	GO:1905867	epididymis development
0.38	GO:0071300	cellular response to retinoic acid
0.37	GO:0043588	skin development
0.37	GO:0042048	olfactory behavior
0.37	GO:0048568	embryonic organ development
0.37	GO:0007283	spermatogenesis
0.37	GO:0048598	embryonic morphogenesis

0.35	GO:0005243	gap junction channel activity
0.33	GO:0005515	protein binding

0.81	GO:0005922	connexin complex
0.41	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0005737	cytoplasm
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

tr|R4GIS0|R4GIS0_CHICK
Inhibin beta B chain
Search

INHBB

0.95	Inhibin beta B subunit

0.75	GO:0010469	regulation of receptor activity
0.61	GO:0032686	negative regulation of hepatocyte growth factor production
0.61	GO:0048176	regulation of hepatocyte growth factor biosynthetic process
0.61	GO:0046882	negative regulation of follicle-stimulating hormone secretion
0.60	GO:0046881	positive regulation of follicle-stimulating hormone secretion
0.59	GO:0060279	positive regulation of ovulation
0.58	GO:0042036	negative regulation of cytokine biosynthetic process
0.58	GO:0032924	activin receptor signaling pathway
0.57	GO:0046676	negative regulation of insulin secretion
0.55	GO:0045444	fat cell differentiation

0.78	GO:0008083	growth factor activity
0.77	GO:0005179	hormone activity
0.51	GO:0042803	protein homodimerization activity
0.49	GO:0005160	transforming growth factor beta receptor binding
0.47	GO:0005125	cytokine activity
0.36	GO:0034711	inhibin binding
0.34	GO:0046982	protein heterodimerization activity
0.34	GO:0046812	host cell surface binding
0.33	GO:0003924	GTPase activity
0.33	GO:0005525	GTP binding

0.66	GO:0005576	extracellular region
0.54	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0071944	cell periphery
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

tr|R4GIS1|R4GIS1_CHICK
Uncharacterized protein
Search

PGF

0.96	Placental growth factor b

0.76	GO:0010469	regulation of receptor activity
0.51	GO:0001658	branching involved in ureteric bud morphogenesis
0.51	GO:0060688	regulation of morphogenesis of a branching structure
0.50	GO:0008284	positive regulation of cell proliferation
0.45	GO:0001936	regulation of endothelial cell proliferation
0.45	GO:0045766	positive regulation of angiogenesis
0.45	GO:0060754	positive regulation of mast cell chemotaxis
0.44	GO:0001525	angiogenesis
0.44	GO:0050930	induction of positive chemotaxis
0.44	GO:0048010	vascular endothelial growth factor receptor signaling pathway

0.78	GO:0008083	growth factor activity
0.62	GO:0008201	heparin binding
0.46	GO:0005172	vascular endothelial growth factor receptor binding
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0046982	protein heterodimerization activity
0.36	GO:0090729	toxin activity

0.47	GO:0005615	extracellular space
0.34	GO:0009986	cell surface
0.30	GO:0016020	membrane

tr|R4GIS3|R4GIS3_CHICK
Uncharacterized protein
Search

NRIP1

0.97	Nuclear receptor interacting protein 1

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.62	GO:0001543	ovarian follicle rupture
0.60	GO:0071392	cellular response to estradiol stimulus
0.59	GO:0032922	circadian regulation of gene expression
0.56	GO:0019915	lipid storage
0.52	GO:0045893	positive regulation of transcription, DNA-templated
0.51	GO:0045892	negative regulation of transcription, DNA-templated
0.36	GO:0030521	androgen receptor signaling pathway
0.34	GO:0097659	nucleic acid-templated transcription
0.33	GO:0010467	gene expression

0.76	GO:0003712	transcription cofactor activity
0.72	GO:0005102	receptor binding
0.58	GO:0001046	core promoter sequence-specific DNA binding
0.56	GO:0042826	histone deacetylase binding
0.52	GO:0008134	transcription factor binding
0.34	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.52	GO:0000785	chromatin
0.49	GO:0031974	membrane-enclosed lumen
0.45	GO:1902494	catalytic complex

tr|R4GIS6|R4GIS6_CHICK
Forkhead-related transciptional factor 1
Search

0.88	Forkhead-related transciptional factor 1

0.57	GO:0006355	regulation of transcription, DNA-templated
0.54	GO:0009653	anatomical structure morphogenesis
0.53	GO:0048513	animal organ development
0.51	GO:0009888	tissue development
0.49	GO:1904888	cranial skeletal system development
0.49	GO:0030154	cell differentiation
0.49	GO:0060022	hard palate development
0.49	GO:0060023	soft palate development
0.48	GO:0060465	pharynx development
0.47	GO:0048522	positive regulation of cellular process

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.37	GO:0008301	DNA binding, bending
0.36	GO:0001012	RNA polymerase II regulatory region DNA binding
0.35	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.40	GO:0005667	transcription factor complex

tr|R4GIT0|R4GIT0_CHICK
Uncharacterized protein
Search

TMEM47

0.96	Transmembrane protein 47

0.33

GO:0005515

protein binding

0.48	GO:0030054	cell junction
0.41	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|R4GIT1|R4GIT1_CHICK
Uncharacterized protein
Search

PIGY

0.97	phosphatidylinositol N-acetylglucosaminyltransferase subunit Y

0.78

GO:0006506

GPI anchor biosynthetic process

0.59

GO:0016757

transferase activity, transferring glycosyl groups

0.86	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
0.41	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.59

EC:2.4

GO:0016757

tr|R4GIT3|R4GIT3_CHICK
Uncharacterized protein
Search

MARCH3

0.91	Membrane associated ring-CH-type finger 3

0.46	GO:0016567	protein ubiquitination
0.40	GO:0006897	endocytosis
0.37	GO:0030097	hemopoiesis
0.33	GO:0000398	mRNA splicing, via spliceosome

0.63	GO:0008270	zinc ion binding
0.52	GO:0016874	ligase activity
0.44	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0003723	RNA binding

0.53	GO:0031410	cytoplasmic vesicle
0.52	GO:0005764	lysosome
0.50	GO:0012505	endomembrane system
0.40	GO:0098805	whole membrane
0.39	GO:0098588	bounding membrane of organelle
0.39	GO:0012506	vesicle membrane
0.37	GO:0044446	intracellular organelle part
0.33	GO:0019013	viral nucleocapsid
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

0.52	EC:6	GO:0016874
0.44	KEGG:R03876	GO:0004842

tr|R4GIT7|R4GIT7_CHICK
Uncharacterized protein
Search

FITM2

0.97	Fat storage inducing transmembrane protein 2

0.84	GO:0019915	lipid storage
0.60	GO:0010890	positive regulation of sequestering of triglyceride
0.59	GO:0035356	cellular triglyceride homeostasis
0.59	GO:0034389	lipid particle organization
0.59	GO:0010866	regulation of triglyceride biosynthetic process
0.50	GO:0007010	cytoskeleton organization
0.49	GO:0022604	regulation of cell morphogenesis
0.43	GO:0008654	phospholipid biosynthetic process
0.33	GO:0005975	carbohydrate metabolic process
0.32	GO:0009057	macromolecule catabolic process

0.35	GO:0004557	alpha-galactosidase activity
0.32	GO:0102483	scopolin beta-glucosidase activity
0.32	GO:0008422	beta-glucosidase activity

0.72	GO:0005789	endoplasmic reticulum membrane
0.45	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:3.2.1.22

GO:0004557

tr|R4GIU0|R4GIU0_CHICK
Uncharacterized protein
Search

ENDOG

0.53	Endonuclease G, mitochondrial

0.58	GO:0006309	apoptotic DNA fragmentation
0.54	GO:0034612	response to tumor necrosis factor
0.52	GO:0043065	positive regulation of apoptotic process
0.51	GO:0001701	in utero embryonic development
0.50	GO:0046677	response to antibiotic
0.42	GO:0036475	neuron death in response to oxidative stress
0.42	GO:1903626	positive regulation of DNA catabolic process
0.41	GO:1902510	regulation of apoptotic DNA fragmentation
0.41	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death
0.40	GO:0032355	response to estradiol

0.54	GO:0046872	metal ion binding
0.53	GO:0004519	endonuclease activity
0.51	GO:0003676	nucleic acid binding
0.38	GO:0004536	deoxyribonuclease activity
0.36	GO:0044540	L-cystine L-cysteine-lyase (deaminating)
0.36	GO:0080146	L-cysteine desulfhydrase activity
0.35	GO:0004123	cystathionine gamma-lyase activity
0.34	GO:0005515	protein binding
0.33	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0004713	protein tyrosine kinase activity

0.44	GO:0005739	mitochondrion
0.40	GO:0043204	perikaryon
0.37	GO:0005829	cytosol
0.36	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.36	EC:4.4.1.1	GO:0044540
0.36	KEGG:R02408	GO:0044540

tr|R4GIU3|R4GIU3_CHICK
Interleukin 34
Search

IL34

0.97	Interleukin-34 isoform A

0.79	GO:0008284	positive regulation of cell proliferation
0.77	GO:0001934	positive regulation of protein phosphorylation
0.61	GO:0045657	positive regulation of monocyte differentiation
0.61	GO:0045651	positive regulation of macrophage differentiation
0.42	GO:0010469	regulation of receptor activity
0.40	GO:0006954	inflammatory response
0.40	GO:0045087	innate immune response
0.35	GO:0019221	cytokine-mediated signaling pathway

0.87	GO:0005157	macrophage colony-stimulating factor receptor binding
0.43	GO:0005125	cytokine activity
0.39	GO:0008083	growth factor activity
0.37	GO:0042802	identical protein binding

0.73	GO:0005615	extracellular space
0.30	GO:0016020	membrane

tr|R4GIU6|R4GIU6_CHICK
Uncharacterized protein
Search

0.65	Voltage-dependent L-type calcium channel subunit beta-1

0.76	GO:0070588	calcium ion transmembrane transport
0.56	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
0.53	GO:1904646	cellular response to amyloid-beta
0.50	GO:0070978	voltage-gated calcium channel complex assembly
0.49	GO:0006936	muscle contraction
0.49	GO:1901385	regulation of voltage-gated calcium channel activity
0.48	GO:0007528	neuromuscular junction development
0.47	GO:0007268	chemical synaptic transmission
0.44	GO:0086045	membrane depolarization during AV node cell action potential
0.43	GO:0086026	atrial cardiac muscle cell to AV node cell signaling

0.81	GO:0005245	voltage-gated calcium channel activity
0.41	GO:0005515	protein binding
0.39	GO:0044877	macromolecular complex binding
0.34	GO:0005246	calcium channel regulator activity

0.80	GO:0005891	voltage-gated calcium channel complex
0.45	GO:0042383	sarcolemma
0.36	GO:0016529	sarcoplasmic reticulum
0.33	GO:0005887	integral component of plasma membrane

tr|R4GIU7|R4GIU7_CHICK
Uncharacterized protein
Search

TSC22D2

0.92	Similar to TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4)

0.62	GO:0006970	response to osmotic stress
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression

0.61

GO:0003700

DNA binding transcription factor activity

0.43	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|R4GIU8|R4GIU8_CHICK
Uncharacterized protein
Search

CDR2L

0.97	Cerebellar degeneration related protein 2 like

0.52

GO:0006415

translational termination

0.53	GO:0003747	translation release factor activity
0.42	GO:0005515	protein binding

0.42

GO:0005737

cytoplasm

tr|R4GIU9|R4GIU9_CHICK
Uncharacterized protein
Search

RNF44

0.90	Ring finger protein 44

0.72	GO:0016567	protein ubiquitination
0.70	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

0.73	GO:0004842	ubiquitin-protein transferase activity
0.69	GO:0061659	ubiquitin-like protein ligase activity
0.39	GO:0046872	metal ion binding

0.56	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.73

GO:0004842

tr|R4GIV3|R4GIV3_CHICK
Uncharacterized protein
Search

0.11	Cardiomyopathy-associated protein 5

0.45	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade
0.45	GO:0014733	regulation of skeletal muscle adaptation
0.43	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.38	GO:0031397	negative regulation of protein ubiquitination
0.38	GO:0035246	peptidyl-arginine N-methylation

0.42	GO:0005515	protein binding
0.38	GO:0016274	protein-arginine N-methyltransferase activity
0.33	GO:0003676	nucleic acid binding

0.50	GO:0031430	M band
0.47	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0043034	costamere
0.36	GO:0005829	cytosol
0.35	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.38

GO:0016274

tr|R4GIV5|R4GIV5_CHICK
Uncharacterized protein
Search

COMMD8

0.97	COMM domain-containing protein 8

0.37	GO:0097659	nucleic acid-templated transcription
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.36	GO:0010467	gene expression
0.35	GO:0034645	cellular macromolecule biosynthetic process
0.35	GO:0006508	proteolysis

0.36	GO:0004252	serine-type endopeptidase activity
0.36	GO:0005515	protein binding

0.68	GO:0005654	nucleoplasm
0.67	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.36

GO:0004252

tr|R4GIV6|R4GIV6_CHICK
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase
Search

HACD4

0.77	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase

0.70	GO:0006633	fatty acid biosynthetic process
0.61	GO:0000038	very long-chain fatty acid metabolic process
0.50	GO:0030148	sphingolipid biosynthetic process

0.85	GO:0102343	3-hydroxy-arachidoyl-CoA dehydratase activity
0.85	GO:0102345	3-hydroxy-lignoceroyl-CoA dehydratase activity
0.85	GO:0102344	3-hydroxy-behenoyl-CoA dehydratase activity
0.85	GO:0102158	very-long-chain 3-hydroxyacyl-CoA dehydratase activity
0.65	GO:0018812	3-hydroxyacyl-CoA dehydratase activity
0.53	GO:0019899	enzyme binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:4.2.1.134

GO:0102343

tr|R4GIV8|R4GIV8_CHICK
Uncharacterized protein
Search

UBE2R2

0.59	Ubiquitin conjugating enzyme E2

0.58	GO:0070936	protein K48-linked ubiquitination
0.56	GO:0006513	protein monoubiquitination
0.47	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.40	GO:0043951	negative regulation of cAMP-mediated signaling
0.40	GO:0035458	cellular response to interferon-beta
0.36	GO:0090261	positive regulation of inclusion body assembly
0.36	GO:0043525	positive regulation of neuron apoptotic process
0.35	GO:0000082	G1/S transition of mitotic cell cycle
0.35	GO:0070848	response to growth factor
0.34	GO:0006270	DNA replication initiation

0.58	GO:0061631	ubiquitin conjugating enzyme activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0061630	ubiquitin protein ligase activity

0.38	GO:0016607	nuclear speck
0.37	GO:0005829	cytosol

tr|R4GIW4|R4GIW4_CHICK
Uncharacterized protein
Search

XPNPEP2

0.71	X-prolyl aminopeptidase (Aminopeptidase P) 2, membrane-bound

0.60	GO:0006508	proteolysis
0.35	GO:0006501	C-terminal protein lipidation

0.74	GO:0070006	metalloaminopeptidase activity
0.51	GO:0046872	metal ion binding

0.54	GO:0070062	extracellular exosome
0.39	GO:0031225	anchored component of membrane
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|R4GIX1|R4GIX1_CHICK
Uncharacterized protein
Search

DROSHA

0.43	Drosha ribonuclease III

0.76	GO:0016075	rRNA catabolic process
0.70	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.63	GO:0006396	RNA processing
0.51	GO:0071359	cellular response to dsRNA
0.51	GO:0035195	gene silencing by miRNA
0.51	GO:2000628	regulation of miRNA metabolic process
0.50	GO:0045589	regulation of regulatory T cell differentiation
0.50	GO:0010586	miRNA metabolic process
0.49	GO:0050830	defense response to Gram-positive bacterium
0.49	GO:0050829	defense response to Gram-negative bacterium

0.78	GO:0032296	double-stranded RNA-specific ribonuclease activity
0.72	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters
0.58	GO:0003723	RNA binding
0.51	GO:0017151	DEAD/H-box RNA helicase binding
0.51	GO:0070412	R-SMAD binding
0.48	GO:0001530	lipopolysaccharide binding
0.46	GO:0042803	protein homodimerization activity
0.31	GO:0046872	metal ion binding

0.52	GO:0070877	microprocessor complex
0.48	GO:0014069	postsynaptic density
0.32	GO:0005730	nucleolus
0.31	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.72

EC:3.1.26

GO:0016891

tr|R4GIX2|R4GIX2_CHICK
Uncharacterized protein
Search

THEMIS2

0.78	Thymocyte selection associated family member 2

0.85

GO:0050852

T cell receptor signaling pathway

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm

tr|R4GIZ1|R4GIZ1_CHICK
Uncharacterized protein
Search

HSD11B2

0.97	11-beta-hydroxysteroid dehydrogenase

0.52	GO:0055114	oxidation-reduction process
0.52	GO:0007565	female pregnancy
0.44	GO:0008211	glucocorticoid metabolic process
0.40	GO:0002017	regulation of blood volume by renal aldosterone
0.40	GO:0033555	multicellular organismal response to stress
0.39	GO:0033993	response to lipid
0.39	GO:0032094	response to food
0.38	GO:1901700	response to oxygen-containing compound
0.38	GO:0042180	cellular ketone metabolic process
0.38	GO:0051492	regulation of stress fiber assembly

0.53	GO:0016491	oxidoreductase activity
0.38	GO:0005496	steroid binding
0.36	GO:0051287	NAD binding

0.38	GO:0005783	endoplasmic reticulum
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.53

EC:1

GO:0016491

tr|R4GIZ2|R4GIZ2_CHICK
Uncharacterized protein
Search

PTX3

0.97	Pentraxin 3, long a

0.84	GO:1903016	negative regulation of exo-alpha-sialidase activity
0.84	GO:0052403	negative regulation by host of symbiont catalytic activity
0.84	GO:0044867	modulation by host of viral catalytic activity
0.84	GO:0044870	modulation by host of viral glycoprotein metabolic process
0.82	GO:0044793	negative regulation by host of viral process
0.82	GO:0008228	opsonization
0.81	GO:0046597	negative regulation of viral entry into host cell
0.80	GO:1903019	negative regulation of glycoprotein metabolic process
0.79	GO:0001878	response to yeast
0.77	GO:0045429	positive regulation of nitric oxide biosynthetic process

0.83	GO:0046790	virion binding
0.82	GO:0001849	complement component C1q binding
0.82	GO:0001872	(1->3)-beta-D-glucan binding
0.67	GO:0042802	identical protein binding
0.40	GO:0046872	metal ion binding
0.34	GO:0008061	chitin binding
0.34	GO:0004930	G-protein coupled receptor activity
0.32	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.66	GO:0005615	extracellular space
0.39	GO:1904724	tertiary granule lumen
0.39	GO:0035580	specific granule lumen
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0004553

tr|R4GIZ3|R4GIZ3_CHICK
Uncharacterized protein
Search

RASSF9

0.97	Peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor

0.74	GO:0016197	endosomal transport
0.60	GO:0007165	signal transduction
0.35	GO:0006605	protein targeting
0.34	GO:0055114	oxidation-reduction process

0.36	GO:0004497	monooxygenase activity
0.35	GO:0005515	protein binding
0.33	GO:0005215	transporter activity

0.54	GO:0012510	trans-Golgi network transport vesicle membrane
0.51	GO:0005768	endosome
0.48	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.34	GO:0000922	spindle pole
0.34	GO:0005815	microtubule organizing center

tr|R4GJ03|R4GJ03_CHICK
Uncharacterized protein
Search

CLRN2

0.97

Clarin 2

0.43	GO:0050885	neuromuscular process controlling balance
0.42	GO:0036466	synaptic vesicle recycling via endosome
0.42	GO:0007605	sensory perception of sound
0.41	GO:0035418	protein localization to synapse
0.40	GO:0120036	plasma membrane bounded cell projection organization
0.40	GO:0050808	synapse organization
0.38	GO:0030031	cell projection assembly
0.38	GO:0070925	organelle assembly
0.38	GO:0002093	auditory receptor cell morphogenesis
0.33	GO:0006508	proteolysis

0.34

GO:0004177

aminopeptidase activity

0.42	GO:0032421	stereocilium bundle
0.40	GO:0035869	ciliary transition zone
0.38	GO:0045202	synapse
0.37	GO:0045178	basal part of cell
0.37	GO:0098858	actin-based cell projection
0.37	GO:0030140	trans-Golgi network transport vesicle
0.36	GO:0043005	neuron projection
0.36	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.4.11

GO:0004177

tr|R4GJ12|R4GJ12_CHICK
Uncharacterized protein
Search

0.68	GO:0048496	maintenance of animal organ identity
0.65	GO:0045494	photoreceptor cell maintenance
0.64	GO:0035315	hair cell differentiation
0.64	GO:0060113	inner ear receptor cell differentiation
0.62	GO:0007605	sensory perception of sound
0.59	GO:0050953	sensory perception of light stimulus
0.51	GO:0045184	establishment of protein localization
0.42	GO:0042462	eye photoreceptor cell development
0.38	GO:0035335	peptidyl-tyrosine dephosphorylation
0.34	GO:0050896	response to stimulus

0.63	GO:0017022	myosin binding
0.62	GO:0005518	collagen binding
0.57	GO:0042803	protein homodimerization activity
0.38	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0005044	scavenger receptor activity

0.69	GO:0060171	stereocilium membrane
0.69	GO:0002142	stereocilia ankle link complex
0.68	GO:1990696	USH2 complex
0.67	GO:1990075	periciliary membrane compartment
0.65	GO:0001917	photoreceptor inner segment
0.65	GO:0032391	photoreceptor connecting cilium
0.62	GO:0036064	ciliary basal body
0.62	GO:0005604	basement membrane
0.61	GO:0016324	apical plasma membrane
0.41	GO:0005737	cytoplasm

0.38

EC:3.1.3.48

GO:0004725

tr|R4GJ14|R4GJ14_CHICK
Sodium channel protein
Search

0.47	Sodium channel protein (Fragment)

0.78	GO:0034765	regulation of ion transmembrane transport
0.77	GO:0035725	sodium ion transmembrane transport
0.52	GO:0019228	neuronal action potential
0.51	GO:0086010	membrane depolarization during action potential
0.50	GO:0051930	regulation of sensory perception of pain
0.47	GO:0019233	sensory perception of pain
0.42	GO:0086001	cardiac muscle cell action potential
0.40	GO:0086028	bundle of His cell to Purkinje myocyte signaling
0.40	GO:0086027	AV node cell to bundle of His cell signaling
0.40	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization

0.84	GO:0005248	voltage-gated sodium channel activity
0.75	GO:0022832	voltage-gated channel activity
0.72	GO:0022839	ion gated channel activity
0.72	GO:0008381	mechanosensitive ion channel activity
0.39	GO:0044325	ion channel binding
0.38	GO:0005509	calcium ion binding

0.83	GO:0001518	voltage-gated sodium channel complex
0.52	GO:0044299	C-fiber
0.38	GO:0043194	axon initial segment
0.38	GO:0033268	node of Ranvier
0.38	GO:0030315	T-tubule
0.38	GO:0014704	intercalated disc
0.37	GO:0030018	Z disc
0.37	GO:0043025	neuronal cell body
0.36	GO:0016604	nuclear body
0.36	GO:0070062	extracellular exosome

tr|R4GJ15|R4GJ15_CHICK
Uncharacterized protein
Search

POMK

0.97	Protein-O-mannose kinase

0.63	GO:0006468	protein phosphorylation
0.55	GO:0006493	protein O-linked glycosylation
0.53	GO:0019233	sensory perception of pain
0.52	GO:0050905	neuromuscular process
0.52	GO:0001764	neuron migration
0.52	GO:0046835	carbohydrate phosphorylation
0.51	GO:0007611	learning or memory
0.50	GO:0007420	brain development
0.45	GO:0036268	swimming
0.41	GO:0061061	muscle structure development

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0019200	carbohydrate kinase activity
0.41	GO:0001871	pattern binding
0.39	GO:0030246	carbohydrate binding
0.35	GO:0008318	protein prenyltransferase activity

0.49	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.35

EC:2.5.1

GO:0008318

tr|R4GJ23|R4GJ23_CHICK
Uncharacterized protein
Search

tr|R4GJ24|R4GJ24_CHICK
Uncharacterized protein
Search

0.97	DBF4-type zinc finger-containing protein 2

0.32

GO:0006508

proteolysis

0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.33	GO:0004222	metalloendopeptidase activity

0.30

GO:0031224

intrinsic component of membrane

0.33

EC:3.4.24

GO:0004222

tr|R4GJ33|R4GJ33_CHICK
Uncharacterized protein
Search

SHISA3

0.86	Shisa family member 3

0.42	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway
0.40	GO:0030178	negative regulation of Wnt signaling pathway
0.37	GO:0007275	multicellular organism development
0.33	GO:0045332	phospholipid translocation
0.33	GO:0000413	protein peptidyl-prolyl isomerization
0.33	GO:0006457	protein folding

0.33	GO:0004012	phospholipid-translocating ATPase activity
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.33	GO:0005515	protein binding
0.32	GO:0000287	magnesium ion binding
0.32	GO:0016874	ligase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005783	endoplasmic reticulum
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.6.3.1

GO:0004012

tr|R4GJ35|R4GJ35_CHICK
Uncharacterized protein
Search

tr|R4GJ36|R4GJ36_CHICK
Uncharacterized protein
Search

MRPS2

0.95	Mitochondrial ribosomal protein S2

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.32	GO:0003723	RNA binding

0.70	GO:0015935	small ribosomal subunit
0.50	GO:0005761	mitochondrial ribosome
0.40	GO:0031080	nuclear pore outer ring
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane

tr|R4GJ51|R4GJ51_CHICK
Uncharacterized protein
Search

0.81	Putative rab subfamily protein of small gtpase

0.44	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.44	GO:0006891	intra-Golgi vesicle-mediated transport
0.43	GO:0042147	retrograde transport, endosome to Golgi
0.35	GO:0072600	establishment of protein localization to Golgi
0.35	GO:0010452	histone H3-K36 methylation
0.35	GO:0018027	peptidyl-lysine dimethylation
0.35	GO:0018026	peptidyl-lysine monomethylation
0.34	GO:0018023	peptidyl-lysine trimethylation
0.33	GO:0006605	protein targeting
0.32	GO:2001141	regulation of RNA biosynthetic process

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0031489	myosin V binding
0.35	GO:0046975	histone methyltransferase activity (H3-K36 specific)
0.34	GO:0003713	transcription coactivator activity

0.45	GO:0005794	Golgi apparatus
0.40	GO:0005829	cytosol
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

tr|R4GJ53|R4GJ53_CHICK
Uncharacterized protein
Search

SUSD3

0.96	Sushi domain-containing protein 3

0.43	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|R4GJ54|R4GJ54_CHICK
Uncharacterized protein
Search

0.10	Docking protein 2 (Fragment)

0.78	GO:0007265	Ras protein signal transduction
0.72	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.40	GO:0016310	phosphorylation
0.40	GO:0002376	immune system process
0.39	GO:0007411	axon guidance
0.39	GO:0016477	cell migration
0.38	GO:0045055	regulated exocytosis
0.38	GO:0001775	cell activation
0.36	GO:0036211	protein modification process
0.35	GO:0044267	cellular protein metabolic process

0.84	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity
0.73	GO:0005057	signal transducer activity, downstream of receptor
0.40	GO:0016301	kinase activity

0.44	GO:0005622	intracellular
0.37	GO:0012506	vesicle membrane
0.37	GO:0005886	plasma membrane
0.37	GO:0098805	whole membrane
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0012505	endomembrane system

tr|R4GJ59|R4GJ59_CHICK
Uncharacterized protein
Search

SARS

0.60	LOW QUALITY PROTEIN: serine--tRNA ligase, cytoplasmic

0.79	GO:0006434	seryl-tRNA aminoacylation
0.46	GO:1904046	negative regulation of vascular endothelial growth factor production
0.43	GO:0016525	negative regulation of angiogenesis
0.42	GO:0000122	negative regulation of transcription by RNA polymerase II
0.41	GO:0097056	selenocysteinyl-tRNA(Sec) biosynthetic process
0.35	GO:0001569	branching involved in blood vessel morphogenesis
0.35	GO:1903670	regulation of sprouting angiogenesis
0.34	GO:0016259	selenocysteine metabolic process
0.33	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.33	GO:0008033	tRNA processing

0.79	GO:0004828	serine-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0001046	core promoter sequence-specific DNA binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0098619	selenocysteine-tRNA ligase activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0003723	RNA binding

0.49	GO:0005737	cytoplasm
0.38	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.79

EC:6.1.1.11

GO:0004828

tr|R4GJ61|R4GJ61_CHICK
Uncharacterized protein
Search

0.93	Homeobox protein Nkx-2.8

0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.56	GO:0048699	generation of neurons
0.55	GO:0035295	tube development
0.55	GO:0048468	cell development
0.55	GO:0048513	animal organ development
0.54	GO:1902680	positive regulation of RNA biosynthetic process
0.52	GO:0050680	negative regulation of epithelial cell proliferation
0.51	GO:0001709	cell fate determination

0.64	GO:0043565	sequence-specific DNA binding
0.54	GO:0044212	transcription regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.51	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0008134	transcription factor binding
0.46	GO:0003713	transcription coactivator activity
0.46	GO:0003682	chromatin binding
0.35	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.32	GO:0016740	transferase activity

0.61	GO:0005634	nucleus
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.32

EC:2

GO:0016740

tr|R4GJ64|R4GJ64_CHICK
Uncharacterized protein
Search

0.10	Transmembrane protein 161A

0.49	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.49	GO:0032526	response to retinoic acid
0.48	GO:0045739	positive regulation of DNA repair
0.48	GO:0034644	cellular response to UV
0.45	GO:0034599	cellular response to oxidative stress
0.33	GO:0045944	positive regulation of transcription by RNA polymerase II
0.32	GO:0006351	transcription, DNA-templated

0.33	GO:0046983	protein dimerization activity
0.33	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding

0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|R4GJ74|R4GJ74_CHICK
Uncharacterized protein
Search

0.95	Putative serine/threonine-protein kinase SgK494 (Fragment)

0.63	GO:0006468	protein phosphorylation
0.45	GO:0051835	positive regulation of synapse structural plasticity
0.44	GO:0060999	positive regulation of dendritic spine development
0.44	GO:0060143	positive regulation of syncytium formation by plasma membrane fusion
0.44	GO:0046827	positive regulation of protein export from nucleus
0.44	GO:1901985	positive regulation of protein acetylation
0.43	GO:0051149	positive regulation of muscle cell differentiation
0.43	GO:0010976	positive regulation of neuron projection development
0.43	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.43	GO:0032091	negative regulation of protein binding

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0005516	calmodulin binding
0.36	GO:0008017	microtubule binding
0.35	GO:0005057	signal transducer activity, downstream of receptor
0.34	GO:0004332	fructose-bisphosphate aldolase activity
0.34	GO:0005509	calcium ion binding

0.37	GO:0005876	spindle microtubule
0.36	GO:0000922	spindle pole
0.36	GO:0005813	centrosome
0.36	GO:0035371	microtubule plus-end
0.35	GO:0072686	mitotic spindle
0.35	GO:0000776	kinetochore
0.35	GO:0044450	microtubule organizing center part
0.33	GO:0005634	nucleus
0.32	GO:0005829	cytosol
0.32	GO:0005925	focal adhesion

0.34

EC:4.1.2.13

GO:0004332

tr|R4GJ75|R4GJ75_CHICK
Mannosyltransferase
Search

PIGZ

0.53	Mannosyltransferase

0.55	GO:0006506	GPI anchor biosynthetic process
0.55	GO:0097502	mannosylation

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.31	GO:0016787	hydrolase activity

0.72	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.65

EC:2.4

GO:0016757

tr|R4GJ83|R4GJ83_CHICK
Uncharacterized protein
Search

ERGIC3

0.89	ERGIC and golgi 3

0.30

GO:0044425

membrane part

tr|R4GJ84|R4GJ84_CHICK
Uncharacterized protein
Search

FPGT

0.96	Fucose-1-phosphate guanylyltransferase

0.37	GO:1903779	regulation of cardiac conduction
0.37	GO:0006468	protein phosphorylation
0.37	GO:0002027	regulation of heart rate
0.35	GO:0006004	fucose metabolic process
0.33	GO:0035556	intracellular signal transduction
0.32	GO:0006508	proteolysis

0.57	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.36	GO:0032555	purine ribonucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.35	GO:0008144	drug binding
0.33	GO:0004871	signal transducer activity
0.32	GO:0004386	helicase activity

0.34	GO:0005829	cytosol
0.32	GO:0005634	nucleus

0.57

EC:2.7

GO:0016772

tr|R4GJ86|R4GJ86_CHICK
Uncharacterized protein
Search

PLPP4

0.96	Phosphatidic acid phosphatase type 2 domain-containing protein 1A

0.79	GO:0046839	phospholipid dephosphorylation
0.43	GO:0006644	phospholipid metabolic process
0.41	GO:0007165	signal transduction
0.35	GO:0006909	phagocytosis
0.35	GO:0002253	activation of immune response
0.34	GO:0002252	immune effector process
0.34	GO:0034968	histone lysine methylation

0.85	GO:0008195	phosphatidate phosphatase activity
0.50	GO:0042802	identical protein binding
0.34	GO:0018024	histone-lysine N-methyltransferase activity
0.32	GO:0046872	metal ion binding

0.43	GO:0005887	integral component of plasma membrane
0.32	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm

0.85

EC:3.1.3.4

GO:0008195

tr|R4GJ93|R4GJ93_CHICK
Uncharacterized protein
Search

tr|R4GJA0|R4GJA0_CHICK
Uncharacterized protein
Search

TAF1C

0.84	TATA box-binding protein-associated factor RNA polymerase I subunit C

0.70	GO:0006360	transcription by RNA polymerase I
0.39	GO:2001141	regulation of RNA biosynthetic process
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression
0.37	GO:0006354	DNA-templated transcription, elongation
0.37	GO:0006366	transcription by RNA polymerase II
0.36	GO:0006353	DNA-templated transcription, termination
0.36	GO:0010604	positive regulation of macromolecule metabolic process
0.36	GO:0006352	DNA-templated transcription, initiation

0.85	GO:0001164	RNA polymerase I CORE element sequence-specific DNA binding
0.39	GO:0005515	protein binding

0.83	GO:0001650	fibrillar center
0.71	GO:0000120	RNA polymerase I transcription factor complex
0.40	GO:0005654	nucleoplasm

tr|R4GJA4|R4GJA4_CHICK
Uncharacterized protein
Search

0.63	Ras-related and estrogen-regulated growth inhibitor

0.60	GO:0007165	signal transduction
0.37	GO:0048382	mesendoderm development
0.37	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.33	GO:0005975	carbohydrate metabolic process

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0005160	transforming growth factor beta receptor binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.34	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.33

GO:0004553

tr|R4GJA5|R4GJA5_CHICK
Uncharacterized protein
Search

IMP4

0.84	U3 small nucleolar ribonucleoprotein snornp component

0.50	GO:0006364	rRNA processing
0.45	GO:0042274	ribosomal small subunit biogenesis
0.34	GO:0016226	iron-sulfur cluster assembly
0.33	GO:0001510	RNA methylation
0.32	GO:0055114	oxidation-reduction process

0.60	GO:0042134	rRNA primary transcript binding
0.57	GO:0030515	snoRNA binding
0.49	GO:0043047	single-stranded telomeric DNA binding
0.37	GO:0030519	snoRNP binding
0.34	GO:0016787	hydrolase activity
0.34	GO:0003958	NADPH-hemoprotein reductase activity
0.34	GO:0005515	protein binding
0.33	GO:0010181	FMN binding
0.33	GO:0050661	NADP binding
0.33	GO:0050660	flavin adenine dinucleotide binding

0.61	GO:0044452	nucleolar part
0.60	GO:0019013	viral nucleocapsid
0.57	GO:0030529	intracellular ribonucleoprotein complex
0.45	GO:0043234	protein complex
0.35	GO:0005654	nucleoplasm
0.34	GO:0016363	nuclear matrix
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016787

tr|R4GJA6|R4GJA6_CHICK
Tetraspanin
Search

TSPAN19

0.57	Tetraspanin

0.49

GO:0007166

cell surface receptor signaling pathway

0.47

GO:0005887

integral component of plasma membrane

tr|R4GJA8|R4GJA8_CHICK
Uncharacterized protein
Search

SPTSSA

0.97	Small subunit of serine palmitoyltransferase A

0.57	GO:0046513	ceramide biosynthetic process
0.45	GO:1904220	regulation of serine C-palmitoyltransferase activity
0.42	GO:0007029	endoplasmic reticulum organization
0.39	GO:0000045	autophagosome assembly

0.62	GO:0016454	C-palmitoyltransferase activity
0.34	GO:0005515	protein binding

0.61	GO:0017059	serine C-palmitoyltransferase complex
0.30	GO:0031224	intrinsic component of membrane

0.62

EC:2.3.1

GO:0016454

tr|R4GJA9|R4GJA9_CHICK
Uncharacterized protein
Search

EMP2

0.97	Epithelial membrane protein 2

0.62	GO:0003093	regulation of glomerular filtration
0.59	GO:0001913	T cell mediated cytotoxicity
0.59	GO:2001212	regulation of vasculogenesis
0.59	GO:0032060	bleb assembly
0.59	GO:2001046	positive regulation of integrin-mediated signaling pathway
0.58	GO:0043534	blood vessel endothelial cell migration
0.58	GO:0034394	protein localization to cell surface
0.58	GO:0045022	early endosome to late endosome transport
0.57	GO:0070252	actin-mediated cell contraction
0.57	GO:0001765	membrane raft assembly

0.56	GO:0005178	integrin binding
0.53	GO:0019901	protein kinase binding

0.55	GO:0016324	apical plasma membrane
0.54	GO:0045121	membrane raft
0.52	GO:0009986	cell surface
0.50	GO:0031410	cytoplasmic vesicle
0.50	GO:0005794	Golgi apparatus
0.48	GO:0005829	cytosol
0.38	GO:0098588	bounding membrane of organelle
0.37	GO:0031984	organelle subcompartment
0.37	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|R4GJB2|R4GJB2_CHICK
Uncharacterized protein
Search

GMNC

0.97	Geminin coiled-coil domain containing

0.75	GO:0006270	DNA replication initiation
0.60	GO:0008283	cell proliferation
0.59	GO:0060271	cilium assembly
0.41	GO:1903251	multi-ciliated epithelial cell differentiation
0.36	GO:0007049	cell cycle

0.77	GO:0003682	chromatin binding
0.32	GO:0005515	protein binding

0.61

GO:0005634

nucleus

tr|R4GJB7|R4GJB7_CHICK
Uncharacterized protein
Search

RGS8

0.97	Regulator of G protein signaling 8

0.66	GO:0043547	positive regulation of GTPase activity
0.62	GO:0007186	G-protein coupled receptor signaling pathway
0.40	GO:0060159	regulation of dopamine receptor signaling pathway
0.39	GO:0095500	acetylcholine receptor signaling pathway
0.38	GO:0009968	negative regulation of signal transduction
0.33	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.33	GO:0043405	regulation of MAP kinase activity

0.67	GO:0005096	GTPase activator activity
0.35	GO:0001965	G-protein alpha-subunit binding

0.40	GO:0005654	nucleoplasm
0.40	GO:0005829	cytosol
0.39	GO:0032809	neuronal cell body membrane
0.39	GO:0043204	perikaryon
0.38	GO:0030425	dendrite
0.38	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.30	GO:0016021	integral component of membrane

tr|R4GJC4|R4GJC4_CHICK
Uncharacterized protein
Search

CMPK2

0.90	Cytidine/uridine monophosphate kinase 2

0.62	GO:0006233	dTDP biosynthetic process
0.61	GO:0071222	cellular response to lipopolysaccharide
0.61	GO:0046939	nucleotide phosphorylation
0.59	GO:0006227	dUDP biosynthetic process
0.57	GO:0009142	nucleoside triphosphate biosynthetic process
0.52	GO:0046075	dTTP metabolic process

0.65	GO:0019201	nucleotide kinase activity
0.63	GO:0016776	phosphotransferase activity, phosphate group as acceptor
0.43	GO:0030554	adenyl nucleotide binding
0.42	GO:0032555	purine ribonucleotide binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.63

EC:2.7.4

GO:0016776

tr|R4GJC5|R4GJC5_CHICK
Uncharacterized protein
Search

TNS4

0.80

Tensin 4

0.52	GO:0035556	intracellular signal transduction
0.51	GO:0008104	protein localization
0.41	GO:0070098	chemokine-mediated signaling pathway
0.38	GO:0006935	chemotaxis
0.38	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:0006915	apoptotic process
0.35	GO:0006954	inflammatory response
0.35	GO:0006955	immune response

0.44	GO:0046872	metal ion binding
0.41	GO:0004950	chemokine receptor activity
0.37	GO:0003779	actin binding

0.61	GO:0005925	focal adhesion
0.40	GO:0005622	intracellular
0.35	GO:0043228	non-membrane-bounded organelle
0.30	GO:0016020	membrane

tr|R4GJC6|R4GJC6_CHICK
Aminomethyltransferase
Search

AMT

0.55	Aminomethyltransferase, mitochondrial

0.74	GO:0006546	glycine catabolic process
0.62	GO:0032259	methylation

0.79	GO:0004047	aminomethyltransferase activity
0.67	GO:0008483	transaminase activity
0.36	GO:0031405	lipoic acid binding

0.59	GO:0005739	mitochondrion
0.48	GO:0005654	nucleoplasm
0.33	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:2.1.2.10

GO:0004047

tr|R4GJD0|R4GJD0_CHICK
Uncharacterized protein
Search

0.52

GO:0071805

potassium ion transmembrane transport

0.54

GO:0005267

potassium channel activity

0.58	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|R4GJD3|R4GJD3_CHICK
Uncharacterized protein
Search

SCARA3

0.97	Scavenger receptor class A member 3

0.38	GO:0034138	toll-like receptor 3 signaling pathway
0.36	GO:0009650	UV protection
0.36	GO:0030162	regulation of proteolysis
0.35	GO:0032836	glomerular basement membrane development
0.35	GO:0051336	regulation of hydrolase activity
0.35	GO:0072577	endothelial cell apoptotic process
0.35	GO:0032268	regulation of cellular protein metabolic process
0.35	GO:0048519	negative regulation of biological process
0.35	GO:0045765	regulation of angiogenesis
0.35	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway

0.45	GO:0005201	extracellular matrix structural constituent
0.35	GO:0005044	scavenger receptor activity
0.35	GO:0005515	protein binding
0.35	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0030246	carbohydrate binding
0.34	GO:0044877	macromolecular complex binding
0.32	GO:0005509	calcium ion binding
0.32	GO:0042302	structural constituent of cuticle

0.50	GO:0005783	endoplasmic reticulum
0.48	GO:0005581	collagen trimer
0.43	GO:0005604	basement membrane
0.36	GO:0098644	complex of collagen trimers
0.35	GO:0000139	Golgi membrane
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0005615	extracellular space
0.35	GO:0099081	supramolecular polymer
0.32	GO:0030056	hemidesmosome
0.30	GO:0016021	integral component of membrane

tr|R4GJD4|R4GJD4_CHICK
Uncharacterized protein
Search

KCNJ8

0.97	ATP-sensitive inward rectifier potassium channel 8

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.59	GO:0099625	ventricular cardiac muscle cell membrane repolarization
0.59	GO:0086013	membrane repolarization during cardiac muscle cell action potential
0.58	GO:0086005	ventricular cardiac muscle cell action potential
0.57	GO:0014070	response to organic cyclic compound
0.57	GO:1901698	response to nitrogen compound
0.56	GO:0099587	inorganic ion import across plasma membrane
0.55	GO:1901700	response to oxygen-containing compound

0.86	GO:0015272	ATP-activated inward rectifier potassium channel activity
0.60	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
0.51	GO:0030506	ankyrin binding
0.49	GO:0044325	ion channel binding
0.42	GO:0017098	sulfonylurea receptor binding
0.38	GO:0030554	adenyl nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0008144	drug binding
0.37	GO:0008022	protein C-terminus binding

0.54	GO:0008282	inward rectifying potassium channel
0.54	GO:0030016	myofibril
0.47	GO:0042383	sarcolemma
0.39	GO:0070852	cell body fiber
0.38	GO:0030673	axolemma
0.38	GO:0014704	intercalated disc
0.37	GO:0001669	acrosomal vesicle
0.37	GO:0043209	myelin sheath
0.37	GO:0043025	neuronal cell body
0.37	GO:0005739	mitochondrion

tr|R4GJD6|R4GJD6_CHICK
Uncharacterized protein
Search

EIF4E

0.79	Eukaryotic translation initiation factor 4ea

0.72	GO:0006413	translational initiation
0.51	GO:0071549	cellular response to dexamethasone stimulus
0.51	GO:0001662	behavioral fear response
0.49	GO:0019827	stem cell population maintenance
0.49	GO:0045665	negative regulation of neuron differentiation
0.47	GO:0000082	G1/S transition of mitotic cell cycle
0.47	GO:0017148	negative regulation of translation
0.46	GO:0045931	positive regulation of mitotic cell cycle
0.38	GO:0030324	lung development
0.35	GO:0010507	negative regulation of autophagy

0.73	GO:0003743	translation initiation factor activity
0.70	GO:0031370	eukaryotic initiation factor 4G binding
0.66	GO:0070491	repressing transcription factor binding
0.57	GO:0019899	enzyme binding
0.49	GO:0000340	RNA 7-methylguanosine cap binding

0.62	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005845	mRNA cap binding complex
0.51	GO:0033391	chromatoid body
0.51	GO:0016281	eukaryotic translation initiation factor 4F complex
0.47	GO:0016442	RISC complex
0.47	GO:0000932	P-body
0.47	GO:0010494	cytoplasmic stress granule
0.43	GO:0005829	cytosol
0.35	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus

tr|R4GJD9|R4GJD9_CHICK
Uncharacterized protein
Search

DERA

0.53	Deoxyribose-phosphate aldolase

0.78	GO:0009264	deoxyribonucleotide catabolic process
0.56	GO:0046121	deoxyribonucleoside catabolic process
0.42	GO:0016052	carbohydrate catabolic process
0.38	GO:0046386	deoxyribose phosphate catabolic process
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0006098	pentose-phosphate shunt
0.33	GO:0000398	mRNA splicing, via spliceosome

0.80

GO:0004139

deoxyribose-phosphate aldolase activity

0.49	GO:0005737	cytoplasm
0.43	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.32	GO:0030529	intracellular ribonucleoprotein complex

0.80	EC:4.1.2.4	GO:0004139
0.80	KEGG:R01066	GO:0004139

tr|R4GJE0|R4GJE0_CHICK
Uncharacterized protein
Search

0.76	Transcription factor HES-1

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0006355	regulation of transcription, DNA-templated
0.55	GO:0007219	Notch signaling pathway
0.55	GO:0021536	diencephalon development
0.54	GO:0050767	regulation of neurogenesis
0.53	GO:0009952	anterior/posterior pattern specification
0.53	GO:0061106	negative regulation of stomach neuroendocrine cell differentiation
0.53	GO:2000974	negative regulation of pro-B cell differentiation
0.53	GO:0007262	STAT protein import into nucleus
0.53	GO:0043009	chordate embryonic development

0.67	GO:0046983	protein dimerization activity
0.55	GO:0003677	DNA binding
0.49	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.49	GO:0042826	histone deacetylase binding
0.46	GO:0051087	chaperone binding
0.46	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0042802	identical protein binding
0.39	GO:0008134	transcription factor binding
0.35	GO:0008432	JUN kinase binding
0.34	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome
0.30	GO:0016020	membrane

0.34

EC:3.2.1.23

GO:0004565

tr|R4GJE2|R4GJE2_CHICK
Uncharacterized protein
Search

ARHGAP29

0.80	Rho GTPase activating protein 29

0.75	GO:0043547	positive regulation of GTPase activity
0.63	GO:0035556	intracellular signal transduction
0.34	GO:0051056	regulation of small GTPase mediated signal transduction

0.76	GO:0005096	GTPase activator activity
0.52	GO:0046872	metal ion binding
0.50	GO:0030165	PDZ domain binding

0.45

GO:0005622

intracellular

tr|R4GJE7|R4GJE7_CHICK
Uncharacterized protein
Search

0.95	Transcription cofactor HES-6

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0006355	regulation of transcription, DNA-templated
0.44	GO:0050767	regulation of neurogenesis
0.42	GO:0007219	Notch signaling pathway
0.41	GO:0048864	stem cell development
0.41	GO:0051961	negative regulation of nervous system development
0.41	GO:0010721	negative regulation of cell development
0.41	GO:0007540	sex determination, establishment of X:A ratio
0.41	GO:0045931	positive regulation of mitotic cell cycle
0.41	GO:0010720	positive regulation of cell development

0.68	GO:0046983	protein dimerization activity
0.55	GO:0003677	DNA binding
0.41	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0001067	regulatory region nucleic acid binding
0.37	GO:0042826	histone deacetylase binding
0.37	GO:0042802	identical protein binding
0.36	GO:0051087	chaperone binding
0.34	GO:0008134	transcription factor binding
0.33	GO:0004565	beta-galactosidase activity

0.61	GO:0005634	nucleus
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0005737	cytoplasm
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

EC:3.2.1.23

GO:0004565

tr|R4GJF1|R4GJF1_CHICK
Cathelicidin-B1
Search

CATHB1

0.95	Cathelicidin-B1

0.72	GO:0006952	defense response
0.54	GO:0009617	response to bacterium
0.40	GO:0006955	immune response

0.66	GO:0005576	extracellular region
0.52	GO:0099512	supramolecular fiber

tr|R4GJF2|R4GJF2_CHICK
Uncharacterized protein
Search

HSD11B1

0.97	corticosteroid 11-beta-dehydrogenase isozyme 1

0.53	GO:0055114	oxidation-reduction process
0.46	GO:0030324	lung development
0.43	GO:0008202	steroid metabolic process
0.38	GO:0042445	hormone metabolic process
0.36	GO:0043456	regulation of pentose-phosphate shunt
0.36	GO:0071392	cellular response to estradiol stimulus
0.35	GO:0008610	lipid biosynthetic process
0.35	GO:0031667	response to nutrient levels
0.34	GO:0016042	lipid catabolic process
0.34	GO:1901361	organic cyclic compound catabolic process

0.54	GO:0016491	oxidoreductase activity
0.35	GO:0005496	steroid binding
0.34	GO:0050661	NADP binding

0.42	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0005791	rough endoplasmic reticulum
0.35	GO:0045177	apical part of cell
0.35	GO:0031965	nuclear membrane
0.30	GO:0031224	intrinsic component of membrane

0.54

EC:1

GO:0016491

tr|R4GJF3|R4GJF3_CHICK
Uncharacterized protein
Search

SPRED1

0.89	EVH1 domain-containing protein 1

0.70	GO:0009966	regulation of signal transduction
0.70	GO:0007275	multicellular organism development
0.51	GO:0090311	regulation of protein deacetylation
0.50	GO:2001022	positive regulation of response to DNA damage stimulus
0.49	GO:0010801	negative regulation of peptidyl-threonine phosphorylation
0.49	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.46	GO:0023056	positive regulation of signaling
0.46	GO:0010647	positive regulation of cell communication
0.46	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis
0.46	GO:0023057	negative regulation of signaling

0.52	GO:0005173	stem cell factor receptor binding
0.49	GO:0030291	protein serine/threonine kinase inhibitor activity
0.47	GO:0019901	protein kinase binding
0.45	GO:0019902	phosphatase binding

0.45	GO:0031410	cytoplasmic vesicle
0.40	GO:0005829	cytosol
0.38	GO:0005634	nucleus
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|R4GJG3|R4GJG3_CHICK
Uncharacterized protein
Search

MIF4GD

0.95	MIF4G domain-containing protein B

0.41

GO:0006417

regulation of translation

0.58	GO:0003723	RNA binding
0.53	GO:0008022	protein C-terminus binding

0.50	GO:0005730	nucleolus
0.48	GO:0005829	cytosol

tr|R4GJG5|R4GJG5_CHICK
Uncharacterized protein
Search

DMRTB1

0.94	DMRT like family B with proline rich C-terminal 1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.36	GO:0007548	sex differentiation
0.36	GO:0007275	multicellular organism development
0.35	GO:0007530	sex determination
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0030154	cell differentiation
0.34	GO:0060179	male mating behavior
0.34	GO:0022602	ovulation cycle process

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.32	GO:0003735	structural constituent of ribosome

0.61	GO:0005634	nucleus
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

tr|R4GJH6|R4GJH6_CHICK
Uncharacterized protein
Search

ITPRIP

0.97	Inositol 1,4,5-trisphosphate receptor-interacting protein (Fragment)

0.62	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.57	GO:0006469	negative regulation of protein kinase activity

0.59	GO:0004860	protein kinase inhibitor activity
0.48	GO:0005515	protein binding

0.48	GO:0005576	extracellular region
0.47	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|R4GJH9|R4GJH9_CHICK
Suppressor of cytokine-signaling 3
Search

SOCS3

0.97	Suppressor of cytokine-signaling 3

0.82	GO:0007259	JAK-STAT cascade
0.75	GO:0043066	negative regulation of apoptotic process
0.68	GO:0016567	protein ubiquitination
0.65	GO:0046426	negative regulation of JAK-STAT cascade
0.60	GO:0046627	negative regulation of insulin receptor signaling pathway
0.57	GO:0060708	spongiotrophoblast differentiation
0.57	GO:0042509	regulation of tyrosine phosphorylation of STAT protein
0.56	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation
0.56	GO:0060670	branching involved in labyrinthine layer morphogenesis
0.56	GO:0060707	trophoblast giant cell differentiation

0.56	GO:0001784	phosphotyrosine residue binding
0.50	GO:0008269	JAK pathway signal transduction adaptor activity
0.50	GO:0005159	insulin-like growth factor receptor binding
0.49	GO:0004860	protein kinase inhibitor activity
0.42	GO:0005131	growth hormone receptor binding
0.33	GO:0097678	SOCS family protein binding
0.33	GO:0005070	SH3/SH2 adaptor activity
0.33	GO:0097677	STAT family protein binding
0.32	GO:0003779	actin binding
0.32	GO:0019901	protein kinase binding

0.45

GO:0005622

intracellular

0.32

GO:0004715

tr|R4GJI3|R4GJI3_CHICK
Sulfotransferase
Search

HS3ST5

0.56	Sulfotransferase

0.59	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification
0.58	GO:0046596	regulation of viral entry into host cell
0.56	GO:0050819	negative regulation of coagulation
0.55	GO:0006477	protein sulfation
0.39	GO:0070925	organelle assembly
0.39	GO:0044782	cilium organization
0.39	GO:0120031	plasma membrane bounded cell projection assembly
0.38	GO:0055013	cardiac muscle cell development
0.38	GO:0060047	heart contraction
0.37	GO:0031032	actomyosin structure organization

0.77

GO:0008146

sulfotransferase activity

0.30

GO:0016020

membrane

0.77

EC:2.8.2

GO:0008146

tr|R4GJI7|R4GJI7_CHICK
Uncharacterized protein
Search

FRMPD3

0.84	LOW QUALITY PROTEIN: FERM and PDZ domain-containing protein 3

0.39	GO:0051835	positive regulation of synapse structural plasticity
0.37	GO:0007165	signal transduction
0.36	GO:0043312	neutrophil degranulation
0.34	GO:0009116	nucleoside metabolic process
0.34	GO:0009156	ribonucleoside monophosphate biosynthetic process
0.34	GO:0009165	nucleotide biosynthetic process

0.38	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.35	GO:0004749	ribose phosphate diphosphokinase activity
0.34	GO:0000287	magnesium ion binding

0.68	GO:0005856	cytoskeleton
0.38	GO:0043197	dendritic spine
0.36	GO:0070821	tertiary granule membrane
0.34	GO:0043234	protein complex
0.33	GO:0005886	plasma membrane

0.35	EC:2.7.6.1	GO:0004749
0.35	KEGG:R01049	GO:0004749

tr|R4GJI9|R4GJI9_CHICK
Uncharacterized protein
Search

0.56	APC membrane recruitment protein 1 (Fragment)

0.43	GO:0006334	nucleosome assembly
0.42	GO:0010824	regulation of centrosome duplication
0.41	GO:0007155	cell adhesion
0.40	GO:0019538	protein metabolic process
0.39	GO:0051234	establishment of localization
0.39	GO:0034504	protein localization to nucleus
0.38	GO:0043412	macromolecule modification
0.38	GO:0034765	regulation of ion transmembrane transport
0.38	GO:0043043	peptide biosynthetic process
0.37	GO:0044260	cellular macromolecule metabolic process

0.45	GO:0005540	hyaluronic acid binding
0.40	GO:0061608	nuclear import signal receptor activity
0.40	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0016740	transferase activity
0.39	GO:0005215	transporter activity
0.39	GO:0019843	rRNA binding
0.39	GO:0003735	structural constituent of ribosome
0.39	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity
0.39	GO:0004109	coproporphyrinogen oxidase activity
0.38	GO:0051920	peroxiredoxin activity

0.42	GO:0000786	nucleosome
0.40	GO:0005634	nucleus
0.38	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.40	EC:2	GO:0016740
0.39	KEGG:R03220	GO:0004109

tr|R4GJJ1|R4GJJ1_CHICK
Uncharacterized protein
Search

MPG

0.58	N-methylpurine DNA glycosylase

0.71	GO:0006284	base-excision repair
0.34	GO:0006307	DNA dealkylation involved in DNA repair

0.76	GO:0003905	alkylbase DNA N-glycosylase activity
0.54	GO:0003677	DNA binding
0.33	GO:0005515	protein binding

0.37	GO:0042645	mitochondrial nucleoid
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.76

EC:3.2.2.21

GO:0003905

tr|R4GJJ3|R4GJJ3_CHICK
Uncharacterized protein
Search

SERTAD4

0.97	SERTA domain-containing protein 4

0.33

GO:0006887

exocytosis

0.59	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|R4GJJ9|R4GJJ9_CHICK
Keratin
Search

0.76	Scale keratin

0.71

GO:0007010

cytoskeleton organization

0.76

GO:0005200

structural constituent of cytoskeleton

0.78	GO:0005882	intermediate filament
0.30	GO:0031224	intrinsic component of membrane

tr|R4GJK4|R4GJK4_CHICK
Uncharacterized protein
Search

0.90	Translocon-associated protein subunit gamma

0.74

GO:0006614

SRP-dependent cotranslational protein targeting to membrane

0.45	GO:0005622	intracellular
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0044422	organelle part
0.36	GO:0043227	membrane-bounded organelle
0.34	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

tr|R4GJK5|R4GJK5_CHICK
Uncharacterized protein
Search

0.90	C-type lectin domain family 12 member B

0.70

GO:0030246

carbohydrate binding

0.30

GO:0044425

membrane part

tr|R4GJL0|R4GJL0_CHICK
Uncharacterized protein
Search

CIB2

0.97	DNA-dependent protein kinase catalytic subunit-interacting protein 2

0.67	GO:0007229	integrin-mediated signaling pathway
0.54	GO:0071318	cellular response to ATP
0.51	GO:0045494	photoreceptor cell maintenance
0.50	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.42	GO:0007638	mechanosensory behavior
0.42	GO:0048884	neuromast development
0.40	GO:0043010	camera-type eye development
0.35	GO:0016310	phosphorylation
0.32	GO:0036211	protein modification process
0.32	GO:0044267	cellular protein metabolic process

0.70	GO:0005509	calcium ion binding
0.50	GO:0005178	integrin binding
0.48	GO:0042803	protein homodimerization activity
0.45	GO:0000287	magnesium ion binding
0.35	GO:0016301	kinase activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0032437	cuticular plate
0.52	GO:0032420	stereocilium
0.52	GO:0005927	muscle tendon junction
0.51	GO:0001917	photoreceptor inner segment
0.50	GO:0001750	photoreceptor outer segment
0.50	GO:0042383	sarcolemma
0.50	GO:0031594	neuromuscular junction
0.36	GO:0072562	blood microparticle

0.33

GO:0016773

tr|R4GJL1|R4GJL1_CHICK
Uncharacterized protein
Search

NIPSNAP3A

0.94	Nipsnap homolog 3A (C. elegans)

0.42	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.41	GO:0007186	G-protein coupled receptor signaling pathway

0.42	GO:0004984	olfactory receptor activity
0.38	GO:0004930	G-protein coupled receptor activity
0.36	GO:0005515	protein binding

0.58	GO:0005739	mitochondrion
0.42	GO:0005829	cytosol
0.38	GO:0005634	nucleus
0.35	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|R4GJL4|R4GJL4_CHICK
Uncharacterized protein
Search

PDZD8

0.97	PDZ domain-containing protein 8

0.61	GO:0035556	intracellular signal transduction
0.58	GO:1990456	mitochondrion-endoplasmic reticulum membrane tethering
0.56	GO:0051560	mitochondrial calcium ion homeostasis
0.49	GO:0007010	cytoskeleton organization
0.48	GO:0022604	regulation of cell morphogenesis
0.36	GO:0006869	lipid transport
0.33	GO:0016032	viral process

0.46	GO:0046872	metal ion binding
0.36	GO:0008289	lipid binding

0.55	GO:0044233	ER-mitochondrion membrane contact site
0.49	GO:0005789	endoplasmic reticulum membrane
0.44	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

tr|R4GJL7|R4GJL7_CHICK
Uncharacterized protein
Search

RHOU

0.95	Rho-related GTP-binding protein RhoU

0.77	GO:0007264	small GTPase mediated signal transduction
0.54	GO:1903955	positive regulation of protein targeting to mitochondrion
0.48	GO:0007010	cytoskeleton organization
0.47	GO:0008360	regulation of cell shape
0.45	GO:0000082	G1/S transition of mitotic cell cycle
0.45	GO:0036302	atrioventricular canal development
0.43	GO:0030029	actin filament-based process
0.41	GO:0030155	regulation of cell adhesion
0.34	GO:0019221	cytokine-mediated signaling pathway
0.34	GO:0051056	regulation of small GTPase mediated signal transduction

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity

0.45	GO:0005622	intracellular
0.38	GO:0005925	focal adhesion
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0042995	cell projection
0.36	GO:0012505	endomembrane system
0.34	GO:0043234	protein complex
0.34	GO:0043228	non-membrane-bounded organelle
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|R4GJL8|R4GJL8_CHICK
Protein FAM60A
Search

tr|R4GJM5|R4GJM5_CHICK
Uncharacterized protein
Search

STBD1

0.86	Starch-binding domain-containing protein 1

0.60	GO:0061723	glycophagy
0.49	GO:0046907	intracellular transport
0.37	GO:0043312	neutrophil degranulation

0.85	GO:2001069	glycogen binding
0.82	GO:2001070	starch binding
0.50	GO:0019899	enzyme binding

0.58	GO:0030315	T-tubule
0.54	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005783	endoplasmic reticulum
0.49	GO:0005829	cytosol
0.48	GO:0005887	integral component of plasma membrane
0.41	GO:0034045	phagophore assembly site membrane
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.37	GO:0101003	ficolin-1-rich granule membrane
0.37	GO:0070821	tertiary granule membrane

tr|R4GJN3|R4GJN3_CHICK
Uncharacterized protein
Search

tr|R4GJN4|R4GJN4_CHICK
Uncharacterized protein
Search

0.53	Heat shock protein 12B

0.47

GO:0010970

transport along microtubule

0.50	GO:0030554	adenyl nucleotide binding
0.49	GO:0097367	carbohydrate derivative binding
0.49	GO:0008144	drug binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0070840	dynein complex binding

0.47	GO:0005869	dynactin complex
0.45	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

tr|R4GJN9|R4GJN9_CHICK
Uncharacterized protein
Search

0.12	Ewing's tumor-associated antigen 1

0.86	GO:2000001	regulation of DNA damage checkpoint
0.84	GO:0031297	replication fork processing
0.80	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.65	GO:0006281	DNA repair

0.85	GO:0043539	protein serine/threonine kinase activator activity
0.49	GO:0005515	protein binding

0.82

GO:0043596

nuclear replication fork

tr|R4GJP5|R4GJP5_CHICK
Uncharacterized protein
Search

GLCE

0.93	Glucuronic acid epimerase a

0.69	GO:0006024	glycosaminoglycan biosynthetic process
0.60	GO:0030202	heparin metabolic process
0.59	GO:0030201	heparan sulfate proteoglycan metabolic process
0.58	GO:0030166	proteoglycan biosynthetic process
0.48	GO:0044272	sulfur compound biosynthetic process
0.37	GO:0009950	dorsal/ventral axis specification

0.72

GO:0016857

racemase and epimerase activity, acting on carbohydrates and derivatives

0.50	GO:0005794	Golgi apparatus
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.72

EC:5.1.3

GO:0016857

tr|R4GJP7|R4GJP7_CHICK
Uncharacterized protein
Search

0.75	GO:0006030	chitin metabolic process
0.37	GO:0006508	proteolysis
0.35	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.34	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.34	GO:0006814	sodium ion transport
0.34	GO:0006813	potassium ion transport
0.34	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.33	GO:0016525	negative regulation of angiogenesis
0.33	GO:0030244	cellulose biosynthetic process
0.33	GO:0006898	receptor-mediated endocytosis

0.74	GO:0008061	chitin binding
0.36	GO:0005509	calcium ion binding
0.35	GO:0005391	sodium:potassium-exchanging ATPase activity
0.33	GO:0005044	scavenger receptor activity
0.33	GO:0016760	cellulose synthase (UDP-forming) activity
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0016746	transferase activity, transferring acyl groups
0.32	GO:0016301	kinase activity

0.65	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.35

EC:3.6.3.9

GO:0005391

tr|R4GJP8|R4GJP8_CHICK
Uncharacterized protein
Search

TSPAN13

0.50	Tetraspanin

0.56	GO:1903169	regulation of calcium ion transmembrane transport
0.48	GO:0065009	regulation of molecular function
0.46	GO:0007166	cell surface receptor signaling pathway
0.34	GO:0008284	positive regulation of cell proliferation

0.57	GO:0005246	calcium channel regulator activity
0.33	GO:0005515	protein binding

0.44

GO:0005887

integral component of plasma membrane

tr|R4GJP9|R4GJP9_CHICK
Histone H2A
Search

tr|R4GJQ0|R4GJQ0_CHICK
Uncharacterized protein
Search

0.86	Interferon type B

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.57	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.57	GO:0002323	natural killer cell activation involved in immune response
0.56	GO:0042100	B cell proliferation
0.55	GO:0002286	T cell activation involved in immune response
0.55	GO:0043330	response to exogenous dsRNA
0.55	GO:0030183	B cell differentiation
0.54	GO:0002250	adaptive immune response
0.53	GO:0006959	humoral immune response

0.81	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.50	GO:0032403	protein complex binding

0.73

GO:0005615

extracellular space

tr|R4GJQ4|R4GJQ4_CHICK
Uncharacterized protein
Search

HRH3

0.88	Histamine H3 receptor long form

0.72	GO:0001505	regulation of neurotransmitter levels
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.50	GO:0007194	negative regulation of adenylate cyclase activity
0.47	GO:0014050	negative regulation of glutamate secretion
0.47	GO:0014063	negative regulation of serotonin secretion
0.47	GO:0014061	regulation of norepinephrine secretion
0.44	GO:0050890	cognition
0.39	GO:0014053	negative regulation of gamma-aminobutyric acid secretion
0.38	GO:0042756	drinking behavior
0.38	GO:0042755	eating behavior

0.86	GO:0004969	histamine receptor activity
0.33	GO:0008144	drug binding

0.38	GO:0097458	neuron part
0.37	GO:0043209	myelin sheath
0.36	GO:0005886	plasma membrane
0.36	GO:0044456	synapse part
0.36	GO:0120025	plasma membrane bounded cell projection
0.30	GO:0016021	integral component of membrane

tr|R4GJQ6|R4GJQ6_CHICK
Protein S100
Search

tr|R4GJR3|R4GJR3_CHICK
Uncharacterized protein
Search

tr|R4GJR8|R4GJR8_CHICK
Uncharacterized protein
Search

SLC25A51

0.97	Mitochondrial carrier triple repeat protein 1

0.47	GO:0006839	mitochondrial transport
0.39	GO:0055085	transmembrane transport
0.32	GO:0016310	phosphorylation
0.31	GO:0046483	heterocycle metabolic process
0.31	GO:1901360	organic cyclic compound metabolic process
0.31	GO:0006725	cellular aromatic compound metabolic process
0.31	GO:0034641	cellular nitrogen compound metabolic process
0.30	GO:0044238	primary metabolic process

0.40	GO:0022857	transmembrane transporter activity
0.34	GO:0005198	structural molecule activity
0.33	GO:0030246	carbohydrate binding
0.32	GO:0004386	helicase activity
0.32	GO:0019205	nucleobase-containing compound kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.43	GO:0005739	mitochondrion
0.41	GO:0019866	organelle inner membrane
0.30	GO:0044425	membrane part

tr|R4GJS1|R4GJS1_CHICK
Uncharacterized protein
Search

BTG2

0.97	BTG anti-proliferation factor 2

0.79	GO:0008285	negative regulation of cell proliferation
0.76	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.74	GO:0021542	dentate gyrus development
0.72	GO:0035914	skeletal muscle cell differentiation
0.71	GO:0008306	associative learning
0.71	GO:0021954	central nervous system neuron development
0.71	GO:2000177	regulation of neural precursor cell proliferation
0.68	GO:0009952	anterior/posterior pattern specification
0.67	GO:0031175	neuron projection development
0.66	GO:0017148	negative regulation of translation

0.52

GO:0019899

enzyme binding

0.47	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm

tr|R4GJS2|R4GJS2_CHICK
Uncharacterized protein
Search

DTX1

0.93	Deltex E3 ubiquitin ligase 1

0.55	GO:0045581	negative regulation of T cell differentiation
0.54	GO:0008593	regulation of Notch signaling pathway
0.54	GO:0045665	negative regulation of neuron differentiation
0.54	GO:1990823	response to leukemia inhibitory factor
0.53	GO:0007219	Notch signaling pathway
0.53	GO:0010001	glial cell differentiation
0.51	GO:0071345	cellular response to cytokine stimulus
0.38	GO:0016567	protein ubiquitination
0.35	GO:0006366	transcription by RNA polymerase II
0.33	GO:1903506	regulation of nucleic acid-templated transcription

0.57	GO:0008270	zinc ion binding
0.56	GO:0005112	Notch binding
0.52	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0016874	ligase activity
0.37	GO:0017124	SH3 domain binding
0.36	GO:0003713	transcription coactivator activity
0.34	GO:0016740	transferase activity

0.52	GO:0016604	nuclear body
0.47	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.47

GO:0016874

tr|R4GJS8|R4GJS8_CHICK
Protein fem-1 homolog B
Search

FEM1B

0.97	Fem-1 homolog b (C. elegans)

0.87	GO:0060743	epithelial cell maturation involved in prostate gland development
0.86	GO:0060442	branching involved in prostate gland morphogenesis
0.86	GO:2000001	regulation of DNA damage checkpoint
0.85	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.81	GO:0051438	regulation of ubiquitin-protein transferase activity
0.73	GO:0016567	protein ubiquitination
0.50	GO:0006915	apoptotic process
0.40	GO:0043687	post-translational protein modification

0.86	GO:0005123	death receptor binding
0.72	GO:0004842	ubiquitin-protein transferase activity

0.69	GO:0005654	nucleoplasm
0.67	GO:0005829	cytosol

0.72

GO:0004842

tr|R4GJT2|R4GJT2_CHICK
Uncharacterized protein
Search

LRRC71

0.64	Leucine-rich repeat-containing protein 71

0.56	GO:0007266	Rho protein signal transduction
0.52	GO:0035023	regulation of Rho protein signal transduction
0.49	GO:0007186	G-protein coupled receptor signaling pathway
0.47	GO:0065009	regulation of molecular function
0.41	GO:0006468	protein phosphorylation

0.53	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.41	GO:0004672	protein kinase activity
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008144	drug binding

0.37	GO:0005622	intracellular
0.30	GO:0044425	membrane part

tr|R4GJT4|R4GJT4_CHICK
Uncharacterized protein
Search

TLDC2

0.91	TLD domain-containing protein 2

0.73

GO:1903204

negative regulation of oxidative stress-induced neuron death

0.30

GO:0044425

membrane part

tr|R4GJT5|R4GJT5_CHICK
Uncharacterized protein
Search

ISLR2

0.93	immunoglobulin superfamily containing leucine-rich repeat protein 2

0.44	GO:0045773	positive regulation of axon extension
0.41	GO:0007155	cell adhesion
0.35	GO:0002576	platelet degranulation
0.32	GO:0006338	chromatin remodeling
0.31	GO:0055085	transmembrane transport

0.36	GO:0005515	protein binding
0.32	GO:0003682	chromatin binding
0.31	GO:0003723	RNA binding

0.48	GO:0005615	extracellular space
0.41	GO:0009986	cell surface
0.36	GO:1903561	extracellular vesicle
0.35	GO:0031093	platelet alpha granule lumen
0.33	GO:0005886	plasma membrane
0.33	GO:0016586	RSC-type complex
0.30	GO:0016021	integral component of membrane

tr|R4GJT6|R4GJT6_CHICK
Uncharacterized protein
Search

LRRC55

0.97	LOW QUALITY PROTEIN: leucine-rich repeat-containing protein 55

0.69	GO:1903818	positive regulation of voltage-gated potassium channel activity
0.58	GO:0071805	potassium ion transmembrane transport
0.52	GO:0007409	axonogenesis
0.39	GO:0006468	protein phosphorylation
0.34	GO:0007165	signal transduction
0.33	GO:0018212	peptidyl-tyrosine modification
0.33	GO:0098656	anion transmembrane transport
0.32	GO:0000186	activation of MAPKK activity
0.32	GO:0042128	nitrate assimilation
0.32	GO:0006270	DNA replication initiation

0.72	GO:0099103	channel activator activity
0.68	GO:0015459	potassium channel regulator activity
0.66	GO:0044325	ion channel binding
0.61	GO:0005249	voltage-gated potassium channel activity
0.40	GO:0004674	protein serine/threonine kinase activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0001653	peptide receptor activity
0.33	GO:0099600	transmembrane receptor activity

0.61	GO:0008076	voltage-gated potassium channel complex
0.50	GO:0005578	proteinaceous extracellular matrix
0.49	GO:0005615	extracellular space
0.34	GO:0009507	chloroplast
0.32	GO:0042555	MCM complex

0.40

GO:0004674

tr|R4GJU1|R4GJU1_CHICK
Uncharacterized protein
Search

0.78	Interleukin-31 receptor subunit alpha

0.80

GO:0019221

cytokine-mediated signaling pathway

0.81

GO:0004896

cytokine receptor activity

0.30

GO:0044425

membrane part

tr|R4GJU5|R4GJU5_CHICK
Uncharacterized protein
Search

SNRNP25

0.96	Small nuclear ribonucleoprotein 25

0.39	GO:0008380	RNA splicing
0.38	GO:0006397	mRNA processing

0.34

GO:0005515

protein binding

0.64	GO:0005689	U12-type spliceosomal complex
0.64	GO:0045171	intercellular bridge
0.63	GO:0019013	viral nucleocapsid
0.54	GO:0005654	nucleoplasm
0.54	GO:0005829	cytosol

tr|R4GJU7|R4GJU7_CHICK
Uncharacterized protein
Search

MXRA7

0.78	Matrix-remodeling-associated protein 7

0.38	GO:0043484	regulation of RNA splicing
0.36	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly
0.36	GO:0032259	methylation
0.36	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:0000186	activation of MAPKK activity
0.35	GO:0006402	mRNA catabolic process
0.35	GO:0000165	MAPK cascade
0.35	GO:0006367	transcription initiation from RNA polymerase II promoter
0.35	GO:0043009	chordate embryonic development
0.34	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.37	GO:0003723	RNA binding
0.36	GO:0008168	methyltransferase activity
0.36	GO:0004871	signal transducer activity
0.36	GO:0008995	ribonuclease E activity
0.35	GO:0000287	magnesium ion binding
0.35	GO:0004521	endoribonuclease activity
0.34	GO:0004674	protein serine/threonine kinase activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding

0.60	GO:0031012	extracellular matrix
0.38	GO:0009898	cytoplasmic side of plasma membrane
0.37	GO:1905360	GTPase complex
0.37	GO:0019897	extrinsic component of plasma membrane
0.35	GO:0019013	viral nucleocapsid
0.35	GO:0005672	transcription factor TFIIA complex
0.35	GO:0098797	plasma membrane protein complex
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.36

GO:0008168

tr|R4GJU8|R4GJU8_CHICK
Uncharacterized protein
Search

NINJ1

0.94	Nerve injury-induced protein 1

0.85	GO:0042246	tissue regeneration
0.72	GO:0007155	cell adhesion
0.57	GO:1990384	hyaloid vascular plexus regression
0.53	GO:0001954	positive regulation of cell-matrix adhesion
0.34	GO:0007399	nervous system development

0.33

GO:0005515

protein binding

0.30

GO:0031224

intrinsic component of membrane

tr|R4GJV3|R4GJV3_CHICK
Uncharacterized protein
Search

TMEM8A

0.69	Post-GPI attachment to proteins factor 6

0.40	GO:0007160	cell-matrix adhesion
0.35	GO:0040008	regulation of growth
0.33	GO:0007346	regulation of mitotic cell cycle

0.36	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.36	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.36	GO:0004623	phospholipase A2 activity
0.34	GO:0003735	structural constituent of ribosome
0.33	GO:0005515	protein binding

0.40	GO:0005886	plasma membrane
0.39	GO:0009986	cell surface
0.38	GO:0005765	lysosomal membrane
0.37	GO:0070062	extracellular exosome
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0005634	nucleus
0.34	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0004623

tr|R4GJV9|R4GJV9_CHICK
Uncharacterized protein
Search

tr|R4GJW5|R4GJW5_CHICK
Wee1-like protein kinase
Search

WEE1

0.92	WEE1 G2 checkpoint kinase

0.71	GO:0018108	peptidyl-tyrosine phosphorylation
0.70	GO:0000278	mitotic cell cycle
0.54	GO:0030010	establishment of cell polarity
0.53	GO:0048812	neuron projection morphogenesis
0.51	GO:0000226	microtubule cytoskeleton organization
0.42	GO:0009416	response to light stimulus
0.37	GO:0051301	cell division
0.37	GO:0051321	meiotic cell cycle
0.36	GO:0051726	regulation of cell cycle
0.35	GO:0044839	cell cycle G2/M phase transition

0.75	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.60	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0004674	protein serine/threonine kinase activity
0.35	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.58	GO:0005634	nucleus
0.48	GO:0031974	membrane-enclosed lumen
0.44	GO:0043232	intracellular non-membrane-bounded organelle
0.43	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm

0.75

GO:0004715

tr|R4GJW7|R4GJW7_CHICK
Uncharacterized protein
Search

CSF2RB

0.73	Cytokine receptor common subunit beta

0.75	GO:0019221	cytokine-mediated signaling pathway
0.42	GO:0002532	production of molecular mediator involved in inflammatory response
0.41	GO:0032496	response to lipopolysaccharide
0.40	GO:0036015	response to interleukin-3
0.39	GO:0007585	respiratory gaseous exchange
0.38	GO:0000165	MAPK cascade
0.38	GO:0001558	regulation of cell growth
0.37	GO:0018108	peptidyl-tyrosine phosphorylation
0.36	GO:0065009	regulation of molecular function

0.77	GO:0004896	cytokine receptor activity
0.37	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.37	GO:0004713	protein tyrosine kinase activity

0.41	GO:0030526	granulocyte macrophage colony-stimulating factor receptor complex
0.33	GO:0005622	intracellular

0.37

GO:0004713

tr|R4GJW9|R4GJW9_CHICK
Uncharacterized protein
Search

TRAIP

0.95	TRAF-interacting protein (Fragment)

0.66	GO:0032688	negative regulation of interferon-beta production
0.66	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
0.55	GO:0016567	protein ubiquitination
0.48	GO:0007165	signal transduction

0.59	GO:0005057	signal transducer activity, downstream of receptor
0.58	GO:0061630	ubiquitin protein ligase activity
0.56	GO:0008270	zinc ion binding
0.36	GO:0003779	actin binding

0.35	GO:0005856	cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

tr|R4GJX0|R4GJX0_CHICK
Uncharacterized protein
Search

NUDT2

0.76	Nucleoside diphosphate-linked moiety X motif 2

0.39	GO:0015967	diadenosine tetraphosphate catabolic process
0.38	GO:0006172	ADP biosynthetic process
0.37	GO:0006915	apoptotic process
0.36	GO:0006167	AMP biosynthetic process
0.36	GO:0006754	ATP biosynthetic process
0.34	GO:0034599	cellular response to oxidative stress
0.33	GO:0006030	chitin metabolic process
0.33	GO:0010951	negative regulation of endopeptidase activity

0.83	GO:0008796	bis(5'-nucleosyl)-tetraphosphatase activity
0.39	GO:0043135	5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0032561	guanyl ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0008061	chitin binding
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding

0.42	GO:0005739	mitochondrion
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0005576	extracellular region
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.83

EC:3.6.1

GO:0008796

tr|R4GJX3|R4GJX3_CHICK
Uncharacterized protein
Search

0.78	Interferon-inducible transmembrane protein 3

0.70	GO:0009607	response to biotic stimulus
0.47	GO:0030282	bone mineralization
0.46	GO:0060349	bone morphogenesis
0.45	GO:0001701	in utero embryonic development
0.40	GO:0046597	negative regulation of viral entry into host cell
0.38	GO:0002252	immune effector process
0.38	GO:0006952	defense response
0.37	GO:0035455	response to interferon-alpha
0.37	GO:0035456	response to interferon-beta
0.37	GO:0045071	negative regulation of viral genome replication

0.41	GO:0005887	integral component of plasma membrane
0.36	GO:0031902	late endosome membrane
0.36	GO:0005765	lysosomal membrane
0.36	GO:0045177	apical part of cell
0.35	GO:0009986	cell surface
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0005634	nucleus

tr|R4GJX5|R4GJX5_CHICK
Uncharacterized protein
Search

MSRA

0.43	mitochondrial peptide methionine sulfoxide reductase

0.52	GO:0055114	oxidation-reduction process
0.46	GO:0036211	protein modification process
0.44	GO:0044267	cellular protein metabolic process
0.34	GO:0007568	aging
0.34	GO:0006555	methionine metabolic process
0.34	GO:0006979	response to oxidative stress

0.78

GO:0008113

peptide-methionine (S)-S-oxide reductase activity

0.46	GO:0015629	actin cytoskeleton
0.45	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.41	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.78

EC:1.8.4 EC:1.8.4.11

GO:0008113

tr|R4GJX8|R4GJX8_CHICK
Uncharacterized protein
Search

0.79	Coiled-coil domain-containing protein 92

0.66	GO:0048312	intracellular distribution of mitochondria
0.54	GO:0060271	cilium assembly
0.40	GO:0006413	translational initiation

0.49	GO:0003723	RNA binding
0.39	GO:0005198	structural molecule activity
0.35	GO:0016788	hydrolase activity, acting on ester bonds

0.53	GO:0005813	centrosome
0.45	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm
0.38	GO:1990904	ribonucleoprotein complex

0.35

EC:3.1

GO:0016788

tr|R4GJY1|R4GJY1_CHICK
Uncharacterized protein
Search

ORMDL3

0.53	ORMDL sphingolipid biosynthesis regulator 3

0.82	GO:0006672	ceramide metabolic process
0.81	GO:0090156	cellular sphingolipid homeostasis
0.74	GO:0090155	negative regulation of sphingolipid biosynthetic process
0.64	GO:2000303	regulation of ceramide biosynthetic process
0.56	GO:0034249	negative regulation of cellular amide metabolic process
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0042176	regulation of protein catabolic process
0.33	GO:0050790	regulation of catalytic activity

0.33	GO:0030234	enzyme regulator activity
0.33	GO:0005515	protein binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.59	GO:0002178	palmitoyltransferase complex
0.35	GO:0035579	specific granule membrane
0.34	GO:1905369	endopeptidase complex
0.33	GO:0043234	protein complex
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|R4GJY8|R4GJY8_CHICK
Uncharacterized protein
Search

UBE2C

0.76	Ubiquitin conjugating enzyme E2 C

0.53	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.52	GO:0000209	protein polyubiquitination
0.51	GO:0010994	free ubiquitin chain polymerization
0.51	GO:0007088	regulation of mitotic nuclear division
0.51	GO:1901990	regulation of mitotic cell cycle phase transition
0.50	GO:0010458	exit from mitosis
0.49	GO:0051785	positive regulation of nuclear division
0.48	GO:1901989	positive regulation of cell cycle phase transition
0.48	GO:0045931	positive regulation of mitotic cell cycle
0.48	GO:1902099	regulation of metaphase/anaphase transition of cell cycle

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0044389	ubiquitin-like protein ligase binding
0.50	GO:0061631	ubiquitin conjugating enzyme activity
0.46	GO:0061630	ubiquitin protein ligase activity
0.37	GO:0016874	ligase activity

0.48	GO:0005680	anaphase-promoting complex
0.43	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane
0.33	GO:0005654	nucleoplasm

0.37

GO:0016874

tr|R4GJY9|R4GJY9_CHICK
Uncharacterized protein
Search

0.53

GO:0035335

peptidyl-tyrosine dephosphorylation

0.53

GO:0004725

protein tyrosine phosphatase activity

0.53

EC:3.1.3.48

GO:0004725

tr|R4GJZ1|R4GJZ1_CHICK
Uncharacterized protein
Search

MPV17

0.93	General transcription factor IIIC subunit 2

0.53	GO:0000002	mitochondrial genome maintenance
0.46	GO:0042592	homeostatic process
0.45	GO:0034614	cellular response to reactive oxygen species
0.40	GO:0006067	ethanol metabolic process
0.40	GO:0032836	glomerular basement membrane development
0.39	GO:2000377	regulation of reactive oxygen species metabolic process
0.38	GO:0048839	inner ear development
0.36	GO:0010469	regulation of receptor activity
0.36	GO:0072593	reactive oxygen species metabolic process
0.33	GO:0098656	anion transmembrane transport

0.37	GO:0005179	hormone activity
0.34	GO:0005452	inorganic anion exchanger activity

0.46	GO:0005739	mitochondrion
0.46	GO:0019866	organelle inner membrane
0.37	GO:0005777	peroxisome
0.35	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|R4GJZ2|R4GJZ2_CHICK
P2X purinoceptor
Search

0.10	Purinergic receptor P2X 6

0.85	GO:0033198	response to ATP
0.84	GO:0035590	purinergic nucleotide receptor signaling pathway
0.79	GO:0060079	excitatory postsynaptic potential
0.61	GO:0098655	cation transmembrane transport
0.53	GO:0002554	serotonin secretion by platelet
0.52	GO:0003056	regulation of vascular smooth muscle contraction
0.51	GO:0007320	insemination
0.50	GO:0046513	ceramide biosynthetic process
0.50	GO:0051260	protein homooligomerization
0.50	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process

0.85	GO:0004931	extracellularly ATP-gated cation channel activity
0.84	GO:0001614	purinergic nucleotide receptor activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.47	GO:0042802	identical protein binding
0.34	GO:0008270	zinc ion binding

0.77	GO:0098794	postsynapse
0.66	GO:0005887	integral component of plasma membrane
0.49	GO:0031229	intrinsic component of nuclear inner membrane
0.48	GO:0009897	external side of plasma membrane
0.48	GO:0030054	cell junction
0.47	GO:0097060	synaptic membrane
0.47	GO:0031301	integral component of organelle membrane
0.38	GO:0005737	cytoplasm
0.37	GO:0043005	neuron projection
0.36	GO:0098857	membrane microdomain

tr|R4GJZ3|R4GJZ3_CHICK
Uncharacterized protein
Search

0.97	Phospholipase A2 inhibitor subunit gamma B

0.72

GO:0043086

negative regulation of catalytic activity

0.86

GO:0004859

phospholipase inhibitor activity

0.66

GO:0005576

extracellular region

tr|R4GJZ6|R4GJZ6_CHICK
Uncharacterized protein
Search

GOLPH3

0.88	Z-linked golgi phosphoprotein 3

0.56	GO:0090164	asymmetric Golgi ribbon formation
0.56	GO:0060352	cell adhesion molecule production
0.55	GO:0043001	Golgi to plasma membrane protein transport
0.54	GO:0050901	leukocyte tethering or rolling
0.53	GO:0048194	Golgi vesicle budding
0.53	GO:0030032	lamellipodium assembly
0.53	GO:0045053	protein retention in Golgi apparatus
0.51	GO:0050714	positive regulation of protein secretion
0.51	GO:0010821	regulation of mitochondrion organization
0.51	GO:0032008	positive regulation of TOR signaling

0.84	GO:0070273	phosphatidylinositol-4-phosphate binding
0.47	GO:0019899	enzyme binding

0.52	GO:0031985	Golgi cisterna
0.52	GO:0005802	trans-Golgi network
0.50	GO:0000139	Golgi membrane
0.47	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.37	GO:0031970	organelle envelope lumen
0.36	GO:0005768	endosome
0.34	GO:0005886	plasma membrane
0.33	GO:0019028	viral capsid
0.30	GO:0031224	intrinsic component of membrane

tr|R4GK04|R4GK04_CHICK
Uncharacterized protein
Search

0.92	Putative G-protein coupled receptor 27

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0097211	cellular response to gonadotropin-releasing hormone
0.52	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
0.50	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
0.48	GO:2001223	negative regulation of neuron migration

0.71	GO:0004930	G-protein coupled receptor activity
0.50	GO:0016500	protein-hormone receptor activity

0.42	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|R4GK12|R4GK12_CHICK
Uncharacterized protein
Search

CDC26

0.96	Cell division cycle 26

0.83	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.80	GO:0030071	regulation of mitotic metaphase/anaphase transition
0.71	GO:0070979	protein K11-linked ubiquitination
0.51	GO:0051301	cell division
0.49	GO:0000278	mitotic cell cycle

0.80	GO:0005680	anaphase-promoting complex
0.59	GO:0005654	nucleoplasm

tr|R4GK17|R4GK17_CHICK
Uncharacterized protein
Search

FAAH2

0.90	Fatty-acid amide hydrolase 2-A

0.37

GO:0019369

arachidonic acid metabolic process

0.51

GO:0016787

hydrolase activity

0.36	GO:0005811	lipid droplet
0.30	GO:0044425	membrane part

0.51

GO:0016787

tr|R4GK19|R4GK19_CHICK
Uncharacterized protein
Search

TNK2

0.91	Tyrosine kinase non-receptor

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.56	GO:0007165	signal transduction
0.56	GO:2000369	regulation of clathrin-dependent endocytosis
0.53	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.48	GO:0046777	protein autophosphorylation
0.47	GO:0045087	innate immune response
0.47	GO:0016477	cell migration
0.46	GO:0042127	regulation of cell proliferation
0.45	GO:0030154	cell differentiation

0.77	GO:0004713	protein tyrosine kinase activity
0.75	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.55	GO:0005154	epidermal growth factor receptor binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0031625	ubiquitin protein ligase binding
0.49	GO:0042802	identical protein binding

0.58	GO:0070436	Grb2-EGFR complex
0.52	GO:0005905	clathrin-coated pit
0.52	GO:0030136	clathrin-coated vesicle
0.48	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.44	GO:0005634	nucleus

0.77

GO:0004713

tr|R4GK20|R4GK20_CHICK
Uncharacterized protein
Search

ANKRD32

0.96	Ankyrin repeat domain 32

0.85	GO:1990166	protein localization to site of double-strand break
0.85	GO:0034184	positive regulation of maintenance of mitotic sister chromatid cohesion
0.83	GO:2000781	positive regulation of double-strand break repair
0.74	GO:0031334	positive regulation of protein complex assembly
0.61	GO:0006974	cellular response to DNA damage stimulus
0.51	GO:0043065	positive regulation of apoptotic process
0.48	GO:0016567	protein ubiquitination
0.46	GO:0046826	negative regulation of protein export from nucleus
0.42	GO:0043066	negative regulation of apoptotic process
0.41	GO:0042325	regulation of phosphorylation

0.74	GO:0031625	ubiquitin protein ligase binding
0.70	GO:0032403	protein complex binding
0.42	GO:0042803	protein homodimerization activity
0.41	GO:0046982	protein heterodimerization activity
0.41	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0003723	RNA binding
0.33	GO:0016301	kinase activity

0.81	GO:0042405	nuclear inclusion body
0.78	GO:0035861	site of double-strand break
0.71	GO:0005813	centrosome
0.68	GO:0000786	nucleosome
0.55	GO:0031436	BRCA1-BARD1 complex
0.47	GO:0005737	cytoplasm
0.44	GO:0070531	BRCA1-A complex
0.43	GO:0016607	nuclear speck
0.42	GO:0035770	ribonucleoprotein granule
0.30	GO:0031224	intrinsic component of membrane

0.41

GO:0004842

tr|R4GK22|R4GK22_CHICK
Collagen alpha-2(IX) chain
Search

COL9A2

0.90	Collagen type IX alpha 2 chain

0.53	GO:0035989	tendon development
0.52	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
0.51	GO:0035987	endodermal cell differentiation
0.51	GO:0001502	cartilage condensation
0.51	GO:0002063	chondrocyte development
0.50	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.50	GO:0030199	collagen fibril organization
0.50	GO:0042472	inner ear morphogenesis
0.49	GO:0006029	proteoglycan metabolic process
0.49	GO:0048704	embryonic skeletal system morphogenesis

0.62	GO:0005201	extracellular matrix structural constituent
0.35	GO:0050840	extracellular matrix binding
0.34	GO:0030674	protein binding, bridging
0.34	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0046872	metal ion binding

0.72	GO:0005581	collagen trimer
0.52	GO:0098643	banded collagen fibril
0.46	GO:0005615	extracellular space
0.36	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016020	membrane

tr|R4GK26|R4GK26_CHICK
Uncharacterized protein
Search

0.87	LOW QUALITY PROTEIN: mediator of RNA polymerase II transcription subunit 26

0.39	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0006351	transcription, DNA-templated

0.41	GO:0001104	RNA polymerase II transcription cofactor activity
0.35	GO:0003713	transcription coactivator activity
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.46	GO:0043234	protein complex
0.45	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|R4GK27|R4GK27_CHICK
Uncharacterized protein
Search

TMEM221

0.84	Transmembrane domain-containing protein (Fragment)

0.30

GO:0044425

membrane part

tr|R4GK35|R4GK35_CHICK
Uncharacterized protein
Search

CELF3

0.91	Trinucleotide repeat containing 4 (Predicted)

0.54	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.54	GO:0030575	nuclear body organization
0.53	GO:0030317	flagellated sperm motility
0.52	GO:0098781	ncRNA transcription
0.51	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.51	GO:0007283	spermatogenesis
0.47	GO:0008380	RNA splicing
0.39	GO:0006397	mRNA processing

0.59

GO:0003723

RNA binding

0.50	GO:0016604	nuclear body
0.38	GO:0005737	cytoplasm

tr|R4GK38|R4GK38_CHICK
Sulfate anion transporter 1
Search

SLC26A1

0.52	Sulfate transporter

0.79	GO:0019532	oxalate transport
0.74	GO:1902358	sulfate transmembrane transport
0.71	GO:1902476	chloride transmembrane transport
0.55	GO:0001503	ossification
0.49	GO:0015701	bicarbonate transport
0.47	GO:0051453	regulation of intracellular pH
0.46	GO:0042391	regulation of membrane potential
0.38	GO:0036269	swimming behavior
0.37	GO:0032474	otolith morphogenesis
0.37	GO:0048884	neuromast development

0.79	GO:0019531	oxalate transmembrane transporter activity
0.77	GO:0008271	secondary active sulfate transmembrane transporter activity
0.76	GO:0015301	anion:anion antiporter activity
0.71	GO:0015108	chloride transmembrane transporter activity
0.49	GO:0015106	bicarbonate transmembrane transporter activity
0.45	GO:0005253	anion channel activity
0.33	GO:0008270	zinc ion binding

0.62	GO:0005887	integral component of plasma membrane
0.37	GO:0016323	basolateral plasma membrane
0.31	GO:0005622	intracellular

tr|R4GK41|R4GK41_CHICK
Uncharacterized protein
Search

LOX

0.75	Lysyl oxidase like protein 1

0.53	GO:0055114	oxidation-reduction process
0.47	GO:0048731	system development
0.43	GO:0048251	elastic fiber assembly
0.42	GO:0030199	collagen fibril organization
0.42	GO:0009790	embryo development
0.41	GO:0035295	tube development
0.40	GO:0009653	anatomical structure morphogenesis
0.39	GO:0061448	connective tissue development
0.38	GO:0061061	muscle structure development
0.37	GO:0032496	response to lipopolysaccharide

0.77	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
0.72	GO:0005507	copper ion binding
0.37	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0005515	protein binding

0.51	GO:0031012	extracellular matrix
0.43	GO:0005615	extracellular space
0.41	GO:0005581	collagen trimer
0.37	GO:0001669	acrosomal vesicle

0.77

EC:1.4.3

GO:0016641

tr|R4GK45|R4GK45_CHICK
Uncharacterized protein
Search

GPHB5

0.96	Glycoprotein hormone beta 5

0.75	GO:0010469	regulation of receptor activity
0.65	GO:0002155	regulation of thyroid hormone mediated signaling pathway
0.60	GO:0030819	positive regulation of cAMP biosynthetic process
0.52	GO:0007166	cell surface receptor signaling pathway
0.47	GO:0009755	hormone-mediated signaling pathway
0.47	GO:0007267	cell-cell signaling
0.45	GO:0007186	G-protein coupled receptor signaling pathway

0.79	GO:0005179	hormone activity
0.63	GO:0031531	thyrotropin-releasing hormone receptor binding
0.53	GO:0046982	protein heterodimerization activity

0.66	GO:0005576	extracellular region
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|R4GK50|R4GK50_CHICK
Uncharacterized protein
Search

ETV3L

0.87	ETS domain-containing transcription factor ERF

0.71	GO:0000122	negative regulation of transcription by RNA polymerase II
0.50	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.46	GO:0008285	negative regulation of cell proliferation
0.44	GO:0030154	cell differentiation
0.36	GO:0006351	transcription, DNA-templated
0.34	GO:0000278	mitotic cell cycle
0.33	GO:0006468	protein phosphorylation

0.73	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.61	GO:0043565	sequence-specific DNA binding
0.49	GO:0017151	DEAD/H-box RNA helicase binding
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003714	transcription corepressor activity
0.43	GO:0003690	double-stranded DNA binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.58	GO:0005634	nucleus
0.46	GO:0017053	transcriptional repressor complex
0.43	GO:0000785	chromatin
0.43	GO:0031974	membrane-enclosed lumen
0.36	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|R4GK54|R4GK54_CHICK
Uncharacterized protein
Search

RRAGD

0.92	Ras-related GTP-binding protein D

0.47	GO:0071230	cellular response to amino acid stimulus
0.46	GO:0032008	positive regulation of TOR signaling
0.45	GO:1990253	cellular response to leucine starvation
0.45	GO:0043201	response to leucine
0.43	GO:1903432	regulation of TORC1 signaling
0.42	GO:0010506	regulation of autophagy
0.38	GO:0007050	cell cycle arrest
0.36	GO:0034613	cellular protein localization

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0003924	GTPase activity
0.41	GO:0046982	protein heterodimerization activity
0.41	GO:0051020	GTPase binding

0.47	GO:1990131	Gtr1-Gtr2 GTPase complex
0.46	GO:0034448	EGO complex
0.45	GO:0005764	lysosome
0.42	GO:0005813	centrosome
0.40	GO:0005634	nucleus
0.39	GO:0031974	membrane-enclosed lumen
0.36	GO:0005829	cytosol

tr|R4GK55|R4GK55_CHICK
Uncharacterized protein
Search

SKAP1

0.65	Src kinase associated phosphoprotein 1

0.56	GO:0002757	immune response-activating signal transduction
0.52	GO:0002768	immune response-regulating cell surface receptor signaling pathway
0.51	GO:0072659	protein localization to plasma membrane
0.50	GO:0016310	phosphorylation
0.50	GO:0048522	positive regulation of cellular process
0.48	GO:0045785	positive regulation of cell adhesion
0.48	GO:0023056	positive regulation of signaling
0.47	GO:0010557	positive regulation of macromolecule biosynthetic process
0.47	GO:0010628	positive regulation of gene expression
0.47	GO:0051173	positive regulation of nitrogen compound metabolic process

0.54	GO:0042169	SH2 domain binding
0.52	GO:0019903	protein phosphatase binding
0.52	GO:0016301	kinase activity
0.52	GO:0005070	SH3/SH2 adaptor activity
0.50	GO:0019901	protein kinase binding
0.36	GO:0032403	protein complex binding
0.34	GO:0017124	SH3 domain binding
0.34	GO:0005096	GTPase activator activity
0.34	GO:0004435	phosphatidylinositol phospholipase C activity
0.33	GO:0043565	sequence-specific DNA binding

0.53	GO:0042101	T cell receptor complex
0.50	GO:0005829	cytosol
0.48	GO:0005911	cell-cell junction
0.46	GO:0005634	nucleus
0.41	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part
0.33	GO:0055037	recycling endosome
0.33	GO:0005769	early endosome
0.33	GO:0098592	cytoplasmic side of apical plasma membrane
0.32	GO:0016323	basolateral plasma membrane

0.34	EC:3.1.4.11	GO:0004435
0.34	KEGG:R03435	GO:0004435

tr|R4GK57|R4GK57_CHICK
Neuronal regeneration-related protein
Search

NREP

0.97	Neuronal regeneration-related protein (Fragment)

0.84

GO:0017015

regulation of transforming growth factor beta receptor signaling pathway

tr|R4GK62|R4GK62_CHICK
Uncharacterized protein
Search

ZBTB25

0.97	Zinc finger and BTB domain-containing protein 25

0.44	GO:0000122	negative regulation of transcription by RNA polymerase II
0.42	GO:0010467	gene expression
0.34	GO:0097659	nucleic acid-templated transcription
0.33	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding
0.33	GO:0003700	DNA binding transcription factor activity

0.50	GO:0005654	nucleoplasm
0.40	GO:0005737	cytoplasm

tr|R4GK64|R4GK64_CHICK
Uncharacterized protein
Search

HDGFL2

0.89	Hepatoma-derived growth factor-related protein 2

0.48

GO:0003677

DNA binding

0.52

GO:0005634

nucleus

tr|R4GK65|R4GK65_CHICK
Uncharacterized protein
Search

OTOP3

0.87	LOW QUALITY PROTEIN: otopetrin-3

0.35

GO:0003676

nucleic acid binding

0.30

GO:0044425

membrane part

tr|R4GK68|R4GK68_CHICK
Uncharacterized protein
Search

0.46	Adenine phosphoribosyltransferase

0.66	GO:0009116	nucleoside metabolic process
0.47	GO:0006168	adenine salvage
0.41	GO:0044209	AMP salvage
0.39	GO:1901659	glycosyl compound biosynthetic process

0.59

GO:0016757

transferase activity, transferring glycosyl groups

0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.59

EC:2.4

GO:0016757

tr|R4GK76|R4GK76_CHICK
Uncharacterized protein
Search

ATG10

0.91	Ubiquitin-like-conjugating enzyme ATG10 isoform A

0.86	GO:0006983	ER overload response
0.77	GO:0006914	autophagy
0.72	GO:0032446	protein modification by small protein conjugation
0.60	GO:0006497	protein lipidation
0.44	GO:0031401	positive regulation of protein modification process
0.39	GO:0015031	protein transport

0.71	GO:0019777	Atg12 transferase activity
0.38	GO:0016874	ligase activity
0.36	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.38

GO:0016874

tr|R4GK77|R4GK77_CHICK
Uncharacterized protein
Search

MRPL54

0.97	Mitochondrial ribosomal protein L54

0.38	GO:0032543	mitochondrial translation
0.35	GO:0006508	proteolysis
0.35	GO:0006415	translational termination
0.35	GO:0006414	translational elongation
0.34	GO:0006030	chitin metabolic process
0.34	GO:0044257	cellular protein catabolic process
0.33	GO:0005975	carbohydrate metabolic process

0.37	GO:0004197	cysteine-type endopeptidase activity
0.35	GO:0003723	RNA binding
0.34	GO:0003735	structural constituent of ribosome
0.34	GO:0070003	threonine-type peptidase activity
0.34	GO:0008061	chitin binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.59	GO:0005840	ribosome
0.55	GO:0005759	mitochondrial matrix
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.34	GO:0005839	proteasome core complex
0.33	GO:0005576	extracellular region

0.37

EC:3.4.22

GO:0004197

tr|R4GK80|R4GK80_CHICK
Cardiac phospholamban
Search

PLN

0.97	Cardiac phospholamban

0.77	GO:0006816	calcium ion transport
0.72	GO:0043086	negative regulation of catalytic activity
0.67	GO:1901877	negative regulation of calcium ion binding
0.67	GO:0086023	adrenergic receptor signaling pathway involved in heart process
0.66	GO:0086092	regulation of the force of heart contraction by cardiac conduction
0.65	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
0.65	GO:1901894	regulation of calcium-transporting ATPase activity
0.65	GO:1901077	regulation of relaxation of muscle
0.64	GO:0010459	negative regulation of heart rate
0.64	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity

0.85	GO:0005246	calcium channel regulator activity
0.82	GO:0042030	ATPase inhibitor activity
0.38	GO:0051117	ATPase binding
0.36	GO:0042802	identical protein binding

0.83	GO:0033017	sarcoplasmic reticulum membrane
0.66	GO:0090534	calcium ion-transporting ATPase complex
0.60	GO:0031966	mitochondrial membrane
0.39	GO:0031982	vesicle
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0043234	protein complex

tr|R4GK82|R4GK82_CHICK
Uncharacterized protein
Search

0.40

GO:0007156

homophilic cell adhesion via plasma membrane adhesion molecules

0.38

GO:0005509

calcium ion binding

0.69	GO:0005654	nucleoplasm
0.68	GO:0005829	cytosol
0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|R4GK91|R4GK91_CHICK
Uncharacterized protein
Search

OTOL1

0.97

Otolin 1

0.43	GO:0048840	otolith development
0.36	GO:2000534	positive regulation of renal albumin absorption
0.36	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process
0.36	GO:1904753	negative regulation of vascular associated smooth muscle cell migration
0.36	GO:2000481	positive regulation of cAMP-dependent protein kinase activity
0.36	GO:0045650	negative regulation of macrophage differentiation
0.36	GO:0030198	extracellular matrix organization
0.36	GO:0033034	positive regulation of myeloid cell apoptotic process
0.36	GO:0071639	positive regulation of monocyte chemotactic protein-1 production
0.36	GO:0030853	negative regulation of granulocyte differentiation

0.42	GO:0005201	extracellular matrix structural constituent
0.36	GO:0033691	sialic acid binding
0.35	GO:0005515	protein binding
0.34	GO:0030545	receptor regulator activity
0.33	GO:0005509	calcium ion binding
0.31	GO:0003676	nucleic acid binding

0.76	GO:0005581	collagen trimer
0.64	GO:0005576	extracellular region
0.34	GO:0009986	cell surface
0.34	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0005938	cell cortex
0.33	GO:0019867	outer membrane
0.33	GO:0099081	supramolecular polymer
0.32	GO:0019012	virion
0.30	GO:0016021	integral component of membrane

tr|R4GK99|R4GK99_CHICK
Uncharacterized protein
Search

RALGAPB

0.90	Ral GTPase activating protein non-catalytic beta subunit

0.75	GO:0051056	regulation of small GTPase mediated signal transduction
0.75	GO:0043547	positive regulation of GTPase activity
0.36	GO:0032484	Ral protein signal transduction
0.36	GO:0060178	regulation of exocyst localization

0.75	GO:0005096	GTPase activator activity
0.50	GO:0046982	protein heterodimerization activity

0.33

GO:0005829

cytosol

tr|R4GKA5|R4GKA5_CHICK
Uncharacterized protein
Search

tr|R4GKB3|R4GKB3_CHICK
Uncharacterized protein
Search

RGS6

0.95	Regulator of G protein signaling 6

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.65	GO:0043547	positive regulation of GTPase activity
0.62	GO:0035556	intracellular signal transduction
0.35	GO:0009968	negative regulation of signal transduction
0.35	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway

0.65	GO:0005096	GTPase activator activity
0.63	GO:0004871	signal transducer activity
0.34	GO:0005515	protein binding

0.80	GO:1905360	GTPase complex
0.79	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.65	GO:0098797	plasma membrane protein complex
0.46	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|R4GKC1|R4GKC1_CHICK
Uncharacterized protein
Search

FBXO42

0.64	Kelch domain-containing protein 3

0.67

GO:0010469

regulation of receptor activity

0.70	GO:0005179	hormone activity
0.69	GO:0008083	growth factor activity
0.49	GO:0005509	calcium ion binding

0.60	GO:0005576	extracellular region
0.48	GO:0071339	MLL1 complex
0.30	GO:0044425	membrane part

tr|R4GKC2|R4GKC2_CHICK
Uncharacterized protein
Search

ACKR3

0.97	C-X-C chemokine receptor type 7

0.82	GO:0001570	vasculogenesis
0.78	GO:0001525	angiogenesis
0.68	GO:0006935	chemotaxis
0.68	GO:0007186	G-protein coupled receptor signaling pathway
0.60	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.59	GO:0031623	receptor internalization
0.58	GO:0070098	chemokine-mediated signaling pathway
0.58	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.47	GO:0048920	posterior lateral line neuromast primordium migration
0.41	GO:0021730	trigeminal sensory nucleus development

0.83	GO:0019956	chemokine binding
0.82	GO:0015026	coreceptor activity
0.69	GO:0004930	G-protein coupled receptor activity
0.56	GO:0004896	cytokine receptor activity
0.56	GO:0005044	scavenger receptor activity
0.55	GO:0001653	peptide receptor activity
0.32	GO:0008289	lipid binding

0.56	GO:0005905	clathrin-coated pit
0.53	GO:0009986	cell surface
0.53	GO:0005768	endosome
0.43	GO:0043231	intracellular membrane-bounded organelle
0.43	GO:0005886	plasma membrane
0.39	GO:0048471	perinuclear region of cytoplasm
0.32	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

tr|R4GKC3|R4GKC3_CHICK
Uncharacterized protein
Search

SDR42E2

0.97	Short chain dehydrogenase/reductase family 42E, member 2

0.78	GO:0006694	steroid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process
0.32	GO:0006012	galactose metabolic process

0.83	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0016853	isomerase activity
0.31	GO:0050662	coenzyme binding

0.33	GO:0005840	ribosome
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0044425	membrane part

0.83

EC:1.1.1.145

GO:0003854

tr|R4GKC4|R4GKC4_CHICK
Uncharacterized protein
Search

KLF13

0.95	Kruppel like factor 9

0.47	GO:0045647	negative regulation of erythrocyte differentiation
0.44	GO:0008285	negative regulation of cell proliferation
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.43	GO:0006366	transcription by RNA polymerase II
0.42	GO:0045893	positive regulation of transcription, DNA-templated
0.40	GO:0031018	endocrine pancreas development
0.34	GO:0048565	digestive tract development
0.34	GO:0060319	primitive erythrocyte differentiation
0.34	GO:1902070	positive regulation of sphingolipid mediated signaling pathway

0.51	GO:0003676	nucleic acid binding
0.45	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.33	GO:0046872	metal ion binding
0.33	GO:0003682	chromatin binding
0.33	GO:0005515	protein binding
0.32	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding

0.37	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|R4GKC6|R4GKC6_CHICK
Uncharacterized protein
Search

0.83	A-kinase anchor protein 13-like

0.78	GO:0035023	regulation of Rho protein signal transduction
0.63	GO:0006468	protein phosphorylation
0.56	GO:0065009	regulation of molecular function
0.53	GO:0035556	intracellular signal transduction
0.50	GO:1900169	regulation of glucocorticoid mediated signaling pathway
0.50	GO:0086023	adrenergic receptor signaling pathway involved in heart process
0.48	GO:0060297	regulation of sarcomere organization
0.48	GO:0046579	positive regulation of Ras protein signal transduction
0.47	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.47	GO:0055007	cardiac muscle cell differentiation

0.85	GO:0004691	cAMP-dependent protein kinase activity
0.65	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.49	GO:0005078	MAP-kinase scaffold activity
0.48	GO:0051018	protein kinase A binding
0.43	GO:0046872	metal ion binding
0.33	GO:0004871	signal transducer activity

0.46	GO:0030864	cortical actin cytoskeleton
0.46	GO:0005884	actin filament
0.43	GO:0005829	cytosol
0.37	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.85

EC:2.7.11.11

GO:0004691

tr|R4GKD1|R4GKD1_CHICK
Guanine nucleotide-binding protein subunit gamma
Search

GNG5

0.71	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.51	GO:0072513	positive regulation of secondary heart field cardioblast proliferation
0.49	GO:2000179	positive regulation of neural precursor cell proliferation
0.37	GO:0071377	cellular response to glucagon stimulus
0.36	GO:0021987	cerebral cortex development
0.36	GO:0032496	response to lipopolysaccharide
0.35	GO:0007368	determination of left/right symmetry
0.32	GO:0005975	carbohydrate metabolic process

0.64	GO:0004871	signal transducer activity
0.55	GO:0030165	PDZ domain binding
0.36	GO:0042301	phosphate ion binding
0.33	GO:0008061	chitin binding
0.33	GO:0003924	GTPase activity
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.81	GO:1905360	GTPase complex
0.80	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.65	GO:0098797	plasma membrane protein complex
0.40	GO:0005739	mitochondrion
0.40	GO:0031680	G-protein beta/gamma-subunit complex
0.38	GO:0070062	extracellular exosome
0.36	GO:0005884	actin filament
0.34	GO:0036064	ciliary basal body
0.34	GO:0005813	centrosome

0.33

GO:0004553

tr|R4GKD4|R4GKD4_CHICK
Uncharacterized protein
Search

CCDC177

0.97	Coiled-coil domain-containing protein 177

tr|R4GKE1|R4GKE1_CHICK
E3 ubiquitin-protein ligase
Search

SIAH3

0.53	E3 ubiquitin-protein ligase

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.72	GO:0016567	protein ubiquitination
0.70	GO:0007275	multicellular organism development
0.56	GO:1903215	negative regulation of protein targeting to mitochondrion
0.50	GO:0031647	regulation of protein stability

0.54	GO:0046872	metal ion binding
0.44	GO:0016874	ligase activity

0.61	GO:0005634	nucleus
0.43	GO:0005739	mitochondrion

0.44

GO:0016874

tr|R4GKE5|R4GKE5_CHICK
Uncharacterized protein
Search

0.49	Ribosome-binding protein 1

0.47	GO:0006334	nucleosome assembly
0.46	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.44	GO:0007186	G-protein coupled receptor signaling pathway
0.42	GO:0010824	regulation of centrosome duplication
0.42	GO:0019538	protein metabolic process
0.41	GO:0032259	methylation
0.40	GO:0007155	cell adhesion
0.40	GO:0043413	macromolecule glycosylation
0.39	GO:0019673	GDP-mannose metabolic process
0.39	GO:1901566	organonitrogen compound biosynthetic process

0.46	GO:0004984	olfactory receptor activity
0.44	GO:0004930	G-protein coupled receptor activity
0.44	GO:0005540	hyaluronic acid binding
0.41	GO:0008270	zinc ion binding
0.41	GO:0016740	transferase activity
0.41	GO:0003676	nucleic acid binding
0.40	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0003735	structural constituent of ribosome
0.39	GO:0008446	GDP-mannose 4,6-dehydratase activity
0.37	GO:0003700	DNA binding transcription factor activity

0.46	GO:0000786	nucleosome
0.39	GO:0005840	ribosome
0.37	GO:0000139	Golgi membrane
0.37	GO:0005886	plasma membrane
0.36	GO:0044445	cytosolic part
0.30	GO:0016021	integral component of membrane

0.41	EC:2	GO:0016740
0.39	KEGG:R00888	GO:0008446

tr|R4GKE9|R4GKE9_CHICK
Uncharacterized protein
Search

SOWAHC

0.94	Ankyrin repeat domain-containing protein SOWAHC

0.36	GO:0016310	phosphorylation
0.35	GO:0006464	cellular protein modification process

0.37	GO:0016301	kinase activity
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.35	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:1905369	endopeptidase complex
0.45	GO:0043234	protein complex
0.38	GO:0044424	intracellular part

0.35

GO:0016773

tr|R4GKF0|R4GKF0_CHICK
Uncharacterized protein
Search

CHCHD10

0.88	coiled-coil-helix-coiled-coil-helix domain-containing protein 2

0.61	GO:0007005	mitochondrion organization
0.58	GO:1900037	regulation of cellular response to hypoxia
0.54	GO:0045944	positive regulation of transcription by RNA polymerase II
0.50	GO:2000984	negative regulation of ATP citrate synthase activity
0.42	GO:0006754	ATP biosynthetic process
0.42	GO:0006091	generation of precursor metabolites and energy
0.41	GO:0009250	glucan biosynthetic process
0.41	GO:0016310	phosphorylation
0.37	GO:0036211	protein modification process
0.36	GO:0055114	oxidation-reduction process

0.50	GO:0008134	transcription factor binding
0.49	GO:0043565	sequence-specific DNA binding
0.44	GO:0004689	phosphorylase kinase activity
0.42	GO:0005516	calmodulin binding
0.38	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0005739	mitochondrion
0.58	GO:0031970	organelle envelope lumen
0.54	GO:0005634	nucleus
0.44	GO:0005964	phosphorylase kinase complex
0.30	GO:0016020	membrane

0.44

EC:2.7.11.19

GO:0004689

tr|R4GKF3|R4GKF3_CHICK
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C
Search

MGAT4C

0.96	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C

0.60	GO:0005975	carbohydrate metabolic process
0.38	GO:0043413	macromolecule glycosylation
0.38	GO:0009101	glycoprotein biosynthetic process
0.35	GO:0006464	cellular protein modification process
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.39	GO:0140103	catalytic activity, acting on a glycoprotein
0.38	GO:0008194	UDP-glycosyltransferase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0004930	G-protein coupled receptor activity

0.38	GO:0000139	Golgi membrane
0.30	GO:0044425	membrane part

0.69

GO:0016758

tr|R4GKH1|R4GKH1_CHICK
Uncharacterized protein
Search

BLCAP

0.97	Bladder cancer-associated protein A

0.54	GO:0030262	apoptotic nuclear changes
0.38	GO:0007049	cell cycle

0.33

GO:0005515

protein binding

0.30

GO:0044425

membrane part

tr|R4GKH5|R4GKH5_CHICK
Uncharacterized protein
Search

SYPL1

0.59	Synaptophysin like 1

0.46	GO:0048168	regulation of neuronal synaptic plasticity
0.41	GO:0006874	cellular calcium ion homeostasis
0.34	GO:0007268	chemical synaptic transmission
0.33	GO:0006508	proteolysis

0.33

GO:0004252

serine-type endopeptidase activity

0.82	GO:0008021	synaptic vesicle
0.50	GO:0030141	secretory granule
0.48	GO:0099501	exocytic vesicle membrane
0.45	GO:0031301	integral component of organelle membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0042470	melanosome
0.33	GO:0005887	integral component of plasma membrane

0.33

GO:0004252

tr|R4GKH7|R4GKH7_CHICK
Uncharacterized protein
Search

ZNF362

0.96	Zinc finger protein 362

0.36	GO:1902269	positive regulation of polyamine transmembrane transport
0.35	GO:0006596	polyamine biosynthetic process
0.35	GO:0043085	positive regulation of catalytic activity
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.51	GO:0003676	nucleic acid binding
0.36	GO:0042978	ornithine decarboxylase activator activity
0.35	GO:0046872	metal ion binding
0.30	GO:0003824	catalytic activity

0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|R4GKI4|R4GKI4_CHICK
Gamma-glutamylcyclotransferase
Search

CHAC1

0.49	Glutathione-specific gamma-glutamylcyclotransferase 1

0.79	GO:0006751	glutathione catabolic process
0.55	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.54	GO:0010955	negative regulation of protein processing
0.54	GO:0045746	negative regulation of Notch signaling pathway
0.49	GO:0022008	neurogenesis
0.38	GO:0006986	response to unfolded protein
0.38	GO:0007219	Notch signaling pathway
0.34	GO:0006750	glutathione biosynthetic process
0.32	GO:0030163	protein catabolic process
0.32	GO:0006629	lipid metabolic process

0.81	GO:0003839	gamma-glutamylcyclotransferase activity
0.60	GO:0016829	lyase activity
0.54	GO:0005112	Notch binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
0.32	GO:0008270	zinc ion binding
0.32	GO:0020037	heme binding

0.51	GO:0005802	trans-Golgi network
0.47	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:2.3.2.4

GO:0003839

tr|R4GKJ0|R4GKJ0_CHICK
Uncharacterized protein
Search

0.48	GO:0006238	CMP salvage
0.44	GO:0044206	UMP salvage
0.38	GO:0016310	phosphorylation

0.44	GO:0019206	nucleoside kinase activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0070062	extracellular exosome
0.47	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|R4GKJ2|R4GKJ2_CHICK
Uncharacterized protein
Search

RAB34

0.96	RAB34, member RAS oncogene family a

0.40	GO:0090385	phagosome-lysosome fusion
0.38	GO:0032418	lysosome localization
0.38	GO:0043001	Golgi to plasma membrane protein transport
0.38	GO:1905171	positive regulation of protein localization to phagocytic vesicle
0.37	GO:0044351	macropinocytosis
0.37	GO:1900426	positive regulation of defense response to bacterium
0.37	GO:0019882	antigen processing and presentation
0.36	GO:0007041	lysosomal transport
0.35	GO:0071333	cellular response to glucose stimulus
0.34	GO:0050714	positive regulation of protein secretion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0030742	GTP-dependent protein binding
0.38	GO:0017160	Ral GTPase binding
0.34	GO:0004623	phospholipase A2 activity

0.39	GO:0030670	phagocytic vesicle membrane
0.37	GO:0001726	ruffle
0.37	GO:0031985	Golgi cisterna
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0031256	leading edge membrane
0.36	GO:0031253	cell projection membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:0005770	late endosome
0.36	GO:0005769	early endosome
0.35	GO:0045202	synapse

0.34

GO:0004623

tr|R4GKJ3|R4GKJ3_CHICK
Uncharacterized protein
Search

0.95	Serine palmitoyltransferase small subunit B

0.51

GO:0016740

transferase activity

0.30

GO:0044425

membrane part

0.51

EC:2

GO:0016740

tr|R4GKJ6|R4GKJ6_CHICK
Uncharacterized protein
Search

0.86	Interferon type B

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.57	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.57	GO:0002323	natural killer cell activation involved in immune response
0.56	GO:0042100	B cell proliferation
0.56	GO:0002286	T cell activation involved in immune response
0.55	GO:0043330	response to exogenous dsRNA
0.55	GO:0030183	B cell differentiation
0.54	GO:0002250	adaptive immune response
0.53	GO:0006959	humoral immune response

0.81	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.50	GO:0032403	protein complex binding

0.73

GO:0005615

extracellular space

tr|R4GKJ9|R4GKJ9_CHICK
Uncharacterized protein
Search

FFAR4

0.97	Free fatty acid receptor 4

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.68	GO:0050710	negative regulation of cytokine secretion
0.68	GO:0046879	hormone secretion
0.67	GO:0010827	regulation of glucose transport
0.67	GO:0050728	negative regulation of inflammatory response
0.66	GO:0045444	fat cell differentiation
0.66	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.62	GO:0043066	negative regulation of apoptotic process
0.52	GO:1901652	response to peptide
0.50	GO:0032870	cellular response to hormone stimulus

0.72	GO:0004930	G-protein coupled receptor activity
0.69	GO:0005504	fatty acid binding
0.69	GO:0008527	taste receptor activity
0.51	GO:0042277	peptide binding
0.35	GO:0005515	protein binding

0.64	GO:0030139	endocytic vesicle
0.48	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|R4GKK2|R4GKK2_CHICK
Uncharacterized protein
Search

0.47	GO:0006414	translational elongation
0.42	GO:0016310	phosphorylation

0.48	GO:0003746	translation elongation factor activity
0.43	GO:0016301	kinase activity

tr|R4GKK6|R4GKK6_CHICK
Uncharacterized protein
Search

SLC26A6

0.81	Solute carrier family 26 (Sulfate transporter), member 6

0.75	GO:0008272	sulfate transport
0.72	GO:0098661	inorganic anion transmembrane transport
0.69	GO:0045852	pH elevation
0.66	GO:0051453	regulation of intracellular pH
0.57	GO:0015701	bicarbonate transport
0.54	GO:0019532	oxalate transport
0.52	GO:0007605	sensory perception of sound
0.52	GO:0006821	chloride transport
0.51	GO:0070633	transepithelial transport
0.50	GO:0071346	cellular response to interferon-gamma

0.78	GO:0008271	secondary active sulfate transmembrane transporter activity
0.66	GO:0015301	anion:anion antiporter activity
0.57	GO:0015106	bicarbonate transmembrane transporter activity
0.54	GO:0019531	oxalate transmembrane transporter activity
0.50	GO:0015108	chloride transmembrane transporter activity
0.46	GO:0005253	anion channel activity
0.45	GO:0004930	G-protein coupled receptor activity
0.44	GO:0005509	calcium ion binding
0.40	GO:0030507	spectrin binding
0.40	GO:0015296	anion:cation symporter activity

0.55	GO:0005887	integral component of plasma membrane
0.51	GO:0016323	basolateral plasma membrane
0.50	GO:0031526	brush border membrane
0.48	GO:0016324	apical plasma membrane
0.40	GO:0016328	lateral plasma membrane
0.38	GO:0097225	sperm midpiece
0.36	GO:0012506	vesicle membrane
0.36	GO:0034707	chloride channel complex
0.35	GO:0044433	cytoplasmic vesicle part
0.35	GO:0005783	endoplasmic reticulum

tr|R4GKL8|R4GKL8_CHICK
Uncharacterized protein
Search

C1QTNF3

0.89	Complement C1q tumor necrosis factor-related protein 3 isoform B

0.42	GO:0070165	positive regulation of adiponectin secretion
0.41	GO:0071638	negative regulation of monocyte chemotactic protein-1 production
0.41	GO:1900165	negative regulation of interleukin-6 secretion
0.41	GO:0035356	cellular triglyceride homeostasis
0.40	GO:0042347	negative regulation of NF-kappaB import into nucleus
0.40	GO:0045721	negative regulation of gluconeogenesis
0.40	GO:0050715	positive regulation of cytokine secretion
0.40	GO:0050728	negative regulation of inflammatory response
0.39	GO:0070206	protein trimerization
0.37	GO:0051897	positive regulation of protein kinase B signaling

0.41	GO:0005201	extracellular matrix structural constituent
0.37	GO:0042302	structural constituent of cuticle
0.36	GO:0005515	protein binding

0.78	GO:0005581	collagen trimer
0.65	GO:0005576	extracellular region
0.35	GO:0031982	vesicle
0.33	GO:0099081	supramolecular polymer
0.33	GO:0030056	hemidesmosome
0.30	GO:0016020	membrane
0.30	GO:0005623	cell

tr|R4GKM0|R4GKM0_CHICK
Uncharacterized protein
Search

EXOC1L

0.75	Exocyst complex component 1 like

0.85	GO:0051601	exocyst localization
0.81	GO:0006893	Golgi to plasma membrane transport
0.77	GO:0006887	exocytosis

0.84	GO:0017049	GTP-Rho binding
0.83	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding

0.79	GO:0000145	exocyst
0.54	GO:0005886	plasma membrane

tr|R4GKM5|R4GKM5_CHICK
Uncharacterized protein
Search

tr|R4GKM8|R4GKM8_CHICK
Uncharacterized protein
Search

CAVIN4

0.97	Caveolae associated protein 4

0.75	GO:0035023	regulation of Rho protein signal transduction
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II
0.44	GO:0007517	muscle organ development
0.42	GO:0033292	T-tubule organization
0.41	GO:0055002	striated muscle cell development
0.41	GO:0014706	striated muscle tissue development
0.40	GO:0014902	myotube differentiation
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:0055006	cardiac cell development
0.35	GO:0007266	Rho protein signal transduction

0.34	GO:0005515	protein binding
0.34	GO:0005096	GTPase activator activity
0.33	GO:0001786	phosphatidylserine binding

0.58	GO:0005901	caveola
0.52	GO:0030018	Z disc
0.39	GO:0042383	sarcolemma
0.37	GO:0005829	cytosol
0.32	GO:0015629	actin cytoskeleton
0.32	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

tr|R4GKM9|R4GKM9_CHICK
G-protein coupled receptor 139
Search

GPR139

0.94	G-protein coupled receptor 139

0.74	GO:0007218	neuropeptide signaling pathway
0.59	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway

0.76	GO:0008188	neuropeptide receptor activity
0.50	GO:0046983	protein dimerization activity

0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|R4GKN1|R4GKN1_CHICK
Uncharacterized protein
Search

0.59	Protein-glutamine gamma-glutamyltransferase 6 (Fragment)

0.84	GO:0018149	peptide cross-linking
0.45	GO:0030216	keratinocyte differentiation
0.41	GO:0051262	protein tetramerization
0.41	GO:0043163	cell envelope organization
0.39	GO:0010838	positive regulation of keratinocyte proliferation
0.37	GO:0045787	positive regulation of cell cycle
0.33	GO:0012501	programmed cell death

0.84	GO:0003810	protein-glutamine gamma-glutamyltransferase activity
0.39	GO:0005509	calcium ion binding
0.32	GO:0005515	protein binding

0.41	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.38	GO:0005737	cytoplasm
0.34	GO:0001533	cornified envelope
0.33	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:2.3.2.13

GO:0003810

tr|R4GKN9|R4GKN9_CHICK
Uncharacterized protein
Search

RHOV

0.97	Rho-related GTP-binding protein RhoV

0.77	GO:0007264	small GTPase mediated signal transduction
0.45	GO:1903955	positive regulation of protein targeting to mitochondrion
0.42	GO:0036302	atrioventricular canal development
0.41	GO:0007010	cytoskeleton organization
0.41	GO:0008360	regulation of cell shape
0.39	GO:0030155	regulation of cell adhesion
0.39	GO:0000082	G1/S transition of mitotic cell cycle
0.37	GO:0030029	actin filament-based process
0.37	GO:0071896	protein localization to adherens junction
0.36	GO:0055113	epiboly involved in gastrulation with mouth forming second

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding
0.32	GO:0003700	DNA binding transcription factor activity

0.45	GO:0005622	intracellular
0.38	GO:0098588	bounding membrane of organelle
0.37	GO:0012505	endomembrane system
0.37	GO:0031982	vesicle
0.37	GO:0098805	whole membrane
0.36	GO:0005925	focal adhesion
0.35	GO:0005886	plasma membrane
0.35	GO:0042995	cell projection
0.34	GO:0043234	protein complex
0.34	GO:0043228	non-membrane-bounded organelle

tr|R4GKP0|R4GKP0_CHICK
Uncharacterized protein
Search

MARVELD2

0.96	MARVEL domain-containing protein 2

0.82	GO:0045216	cell-cell junction organization
0.81	GO:0007605	sensory perception of sound
0.56	GO:0061028	establishment of endothelial barrier
0.55	GO:0034329	cell junction assembly
0.38	GO:0051414	response to cortisol
0.37	GO:0070542	response to fatty acid
0.34	GO:0006414	translational elongation
0.32	GO:0055085	transmembrane transport

0.34	GO:0003746	translation elongation factor activity
0.33	GO:0005515	protein binding

0.86	GO:0061689	tricellular tight junction
0.53	GO:0005923	bicellular tight junction
0.53	GO:0016323	basolateral plasma membrane
0.53	GO:0016324	apical plasma membrane
0.49	GO:0031410	cytoplasmic vesicle
0.41	GO:0033010	paranodal junction
0.41	GO:0043220	Schmidt-Lanterman incisure
0.30	GO:0016021	integral component of membrane

tr|R4GKP1|R4GKP1_CHICK
Uncharacterized protein
Search

tr|R4GKP5|R4GKP5_CHICK
Uncharacterized protein
Search

BORCS6

0.80	BLOC-1 related complex subunit 6

0.83	GO:0032418	lysosome localization
0.47	GO:0043988	histone H3-S28 phosphorylation
0.45	GO:0032467	positive regulation of cytokinesis
0.45	GO:0031577	spindle checkpoint
0.43	GO:0000278	mitotic cell cycle
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression

0.41	GO:0004674	protein serine/threonine kinase activity
0.39	GO:0005515	protein binding
0.39	GO:0003697	single-stranded DNA binding
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0046872	metal ion binding

0.85	GO:0099078	BORC complex
0.51	GO:0005765	lysosomal membrane
0.46	GO:0032133	chromosome passenger complex
0.30	GO:0031224	intrinsic component of membrane

0.41

GO:0004674

tr|R4GKP9|R4GKP9_CHICK
Keratin
Search

0.82	Feather beta keratin

0.71

GO:0007010

cytoskeleton organization

0.77

GO:0005200

structural constituent of cytoskeleton

0.79

GO:0005882

intermediate filament

tr|R4GKQ0|R4GKQ0_CHICK
Uncharacterized protein
Search

MSMP

0.93	Microseminoprotein, prostate associated

0.67	GO:0005615	extracellular space
0.46	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|R4GKQ2|R4GKQ2_CHICK
Uncharacterized protein
Search

SENP8

0.97	Sentrin-specific protease 8

0.61	GO:0006508	proteolysis
0.45	GO:0070647	protein modification by small protein conjugation or removal
0.45	GO:0018205	peptidyl-lysine modification
0.37	GO:0043065	positive regulation of apoptotic process
0.34	GO:0043687	post-translational protein modification
0.33	GO:1902017	regulation of cilium assembly
0.32	GO:0098656	anion transmembrane transport
0.32	GO:0035023	regulation of Rho protein signal transduction
0.32	GO:0065009	regulation of molecular function
0.32	GO:0035556	intracellular signal transduction

0.72	GO:0008234	cysteine-type peptidase activity
0.42	GO:0004175	endopeptidase activity
0.33	GO:0102490	8-oxo-dGTP phosphohydrolase activity
0.33	GO:0102491	dGTP phosphohydrolase activity
0.33	GO:0102486	dCTP phosphohydrolase activity
0.33	GO:0102487	dUTP phosphohydrolase activity
0.33	GO:0102485	dATP phosphohydrolase activity
0.33	GO:0102488	dTTP phosphohydrolase activity
0.33	GO:0102489	GTP phosphohydrolase activity
0.33	GO:0008308	voltage-gated anion channel activity

0.41	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.33	GO:0005741	mitochondrial outer membrane
0.30	GO:0016021	integral component of membrane

0.72

GO:0008234

tr|R4GKR1|R4GKR1_CHICK
Uncharacterized protein
Search

IL5RA

0.97	Interleukin 5 receptor subunit alpha

0.79	GO:0019221	cytokine-mediated signaling pathway
0.61	GO:0032674	regulation of interleukin-5 production
0.61	GO:0002437	inflammatory response to antigenic stimulus
0.36	GO:0008283	cell proliferation
0.35	GO:0000165	MAPK cascade
0.35	GO:0018108	peptidyl-tyrosine phosphorylation
0.34	GO:0065009	regulation of molecular function

0.81	GO:0004896	cytokine receptor activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0004713	protein tyrosine kinase activity

0.35	GO:0005615	extracellular space
0.33	GO:0005886	plasma membrane
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.35

GO:0004713

tr|R4GKR3|R4GKR3_CHICK
Uncharacterized protein
Search

FIG4

0.87	FIG4 phosphoinositide 5-phosphatase

0.72	GO:0031642	negative regulation of myelination
0.70	GO:0032288	myelin assembly
0.66	GO:0043473	pigmentation
0.65	GO:0007626	locomotory behavior
0.64	GO:0007033	vacuole organization
0.62	GO:0048666	neuron development
0.59	GO:0046488	phosphatidylinositol metabolic process
0.37	GO:0010976	positive regulation of neuron projection development
0.35	GO:0016311	dephosphorylation

0.68

GO:0042578

phosphoric ester hydrolase activity

0.66	GO:0005811	lipid droplet
0.63	GO:0010008	endosome membrane
0.48	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0055037	recycling endosome
0.30	GO:0031224	intrinsic component of membrane

0.68

EC:3.1

GO:0042578

tr|R4GKR4|R4GKR4_CHICK
Uncharacterized protein
Search

TMEM27

0.70	Transmembrane protein 27

0.61	GO:0006508	proteolysis
0.59	GO:0035543	positive regulation of SNARE complex assembly
0.58	GO:0045956	positive regulation of calcium ion-dependent exocytosis
0.58	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
0.56	GO:0051957	positive regulation of amino acid transport
0.43	GO:0003051	angiotensin-mediated drinking behavior
0.42	GO:1903598	positive regulation of gap junction assembly
0.42	GO:0032800	receptor biosynthetic process
0.42	GO:0015827	tryptophan transport
0.42	GO:0060452	positive regulation of cardiac muscle contraction

0.84	GO:0008241	peptidyl-dipeptidase activity
0.67	GO:0008237	metallopeptidase activity
0.48	GO:0004180	carboxypeptidase activity
0.43	GO:0104005	hijacked molecular function
0.40	GO:0046872	metal ion binding
0.37	GO:0004175	endopeptidase activity
0.35	GO:0005515	protein binding
0.34	GO:0050660	flavin adenine dinucleotide binding
0.34	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors

0.55	GO:0031526	brush border membrane
0.40	GO:0005615	extracellular space
0.40	GO:0009986	cell surface
0.40	GO:0005737	cytoplasm
0.37	GO:1903561	extracellular vesicle
0.33	GO:0045121	membrane raft
0.30	GO:0016021	integral component of membrane

0.84

EC:3.4.15

GO:0008241

tr|R4GKR5|R4GKR5_CHICK
Uncharacterized protein
Search

PURG

0.97	Purine-rich element-binding protein gamma

0.55	GO:0003677	DNA binding
0.51	GO:0003723	RNA binding

0.61

GO:0005634

nucleus

tr|R4GKR7|R4GKR7_CHICK
Uncharacterized protein
Search

CPLX2

0.95	Complexin 2

0.76	GO:0006836	neurotransmitter transport
0.53	GO:0031915	positive regulation of synaptic plasticity
0.48	GO:0045055	regulated exocytosis
0.48	GO:0030073	insulin secretion
0.48	GO:0048489	synaptic vesicle transport
0.48	GO:0099504	synaptic vesicle cycle
0.48	GO:0099643	signal release from synapse
0.48	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.44	GO:0001505	regulation of neurotransmitter levels
0.39	GO:0002279	mast cell activation involved in immune response

0.84	GO:0019905	syntaxin binding
0.45	GO:0005326	neurotransmitter transporter activity
0.38	GO:0048306	calcium-dependent protein binding

0.48	GO:0031201	SNARE complex
0.47	GO:0098793	presynapse
0.40	GO:0044306	neuron projection terminus
0.40	GO:0033267	axon part
0.40	GO:0005829	cytosol
0.39	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite
0.39	GO:0042629	mast cell granule
0.34	GO:0030054	cell junction
0.33	GO:0005634	nucleus

tr|R4GKR8|R4GKR8_CHICK
Uncharacterized protein
Search

0.10	Putative transcription regulator xnp/atrx dead-box superfamily (Fragment)

0.64	GO:0031297	replication fork processing
0.59	GO:0051301	cell division
0.51	GO:0006974	cellular response to DNA damage stimulus
0.34	GO:0007049	cell cycle
0.34	GO:0071459	protein localization to chromosome, centromeric region
0.33	GO:0051303	establishment of chromosome localization
0.33	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.33	GO:0000280	nuclear division
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.35	GO:0003677	DNA binding
0.34	GO:0051721	protein phosphatase 2A binding
0.33	GO:0004864	protein phosphatase inhibitor activity

0.55	GO:0005654	nucleoplasm
0.38	GO:0005694	chromosome
0.35	GO:0005815	microtubule organizing center
0.33	GO:0005876	spindle microtubule
0.33	GO:0043234	protein complex
0.33	GO:0000922	spindle pole
0.32	GO:0005737	cytoplasm

tr|R4GKS0|R4GKS0_CHICK
Uncharacterized protein
Search

RELL2

0.89	RELT like 2

0.53	GO:0010811	positive regulation of cell-substrate adhesion
0.33	GO:0032259	methylation

0.52	GO:0005518	collagen binding
0.33	GO:0008168	methyltransferase activity

0.52	GO:0005604	basement membrane
0.41	GO:0015630	microtubule cytoskeleton
0.38	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008168

tr|R4GKS2|R4GKS2_CHICK
Uncharacterized protein
Search

0.68	GO:0016311	dephosphorylation
0.44	GO:0030258	lipid modification
0.42	GO:0006644	phospholipid metabolic process
0.40	GO:0007165	signal transduction
0.34	GO:0030148	sphingolipid biosynthetic process
0.33	GO:0006464	cellular protein modification process

0.85	GO:0008195	phosphatidate phosphatase activity
0.49	GO:0042577	lipid phosphatase activity
0.35	GO:0042392	sphingosine-1-phosphate phosphatase activity
0.34	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0003677	DNA binding
0.33	GO:0005515	protein binding

0.42	GO:0005887	integral component of plasma membrane
0.34	GO:0005634	nucleus

0.85

EC:3.1.3.4

GO:0008195

tr|R4GKS6|R4GKS6_CHICK
Uncharacterized protein
Search

tr|R4GKS8|R4GKS8_CHICK
Uncharacterized protein
Search

TCTEX1D2

0.95	Tctex1 domain-containing protein 2

0.85	GO:1905799	regulation of intraciliary retrograde transport
0.68	GO:1902017	regulation of cilium assembly
0.63	GO:0060271	cilium assembly

0.68

GO:0045505

dynein intermediate chain binding

0.70	GO:0031021	interphase microtubule organizing center
0.68	GO:0097546	ciliary base
0.65	GO:0005868	cytoplasmic dynein complex
0.65	GO:0005930	axoneme
0.63	GO:0000922	spindle pole
0.62	GO:0005813	centrosome
0.30	GO:0031224	intrinsic component of membrane

tr|R4GKS9|R4GKS9_CHICK
Uncharacterized protein
Search

ZMYM2

0.92	Zinc finger MYM-type containing 2

0.43	GO:0007010	cytoskeleton organization
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.42	GO:0007275	multicellular organism development
0.42	GO:0022604	regulation of cell morphogenesis
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:0018108	peptidyl-tyrosine phosphorylation

0.62	GO:0008270	zinc ion binding
0.56	GO:0031624	ubiquitin conjugating enzyme binding
0.43	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.38	GO:0003677	DNA binding
0.35	GO:0004713	protein tyrosine kinase activity

0.55	GO:0016605	PML body
0.36	GO:0005737	cytoplasm

0.35

GO:0004713

tr|R4GKT9|R4GKT9_CHICK
Uncharacterized protein
Search

0.10	Exophilin-5 (Fragment)

0.71	GO:0045921	positive regulation of exocytosis
0.70	GO:0050714	positive regulation of protein secretion
0.69	GO:0003334	keratinocyte development
0.68	GO:0071985	multivesicular body sorting pathway
0.65	GO:0006886	intracellular protein transport

0.81

GO:0017137

Rab GTPase binding

0.64

GO:0005768

endosome

tr|R4GKV3|R4GKV3_CHICK
Uncharacterized protein
Search

MINDY1

0.97	Ubiquitin carboxyl-terminal hydrolase MINDY-1

0.85

GO:0071108

protein K48-linked deubiquitination

0.85	GO:1990380	Lys48-specific deubiquitinase activity
0.80	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.62	GO:0070004	cysteine-type exopeptidase activity
0.62	GO:0036435	K48-linked polyubiquitin modification-dependent protein binding
0.52	GO:0004180	carboxypeptidase activity
0.48	GO:0071795	K11-linked polyubiquitin modification-dependent protein binding
0.48	GO:0071796	K6-linked polyubiquitin modification-dependent protein binding
0.46	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding
0.32	GO:0003677	DNA binding

0.51	GO:0016604	nuclear body
0.36	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part

tr|R4GKV5|R4GKV5_CHICK
Uncharacterized protein
Search

EMC6

0.67	ER membrane protein complex subunit 6

0.56	GO:0000045	autophagosome assembly
0.48	GO:0034975	protein folding in endoplasmic reticulum

0.35	GO:0003723	RNA binding
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0005515	protein binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.83	GO:0072546	ER membrane protein complex
0.59	GO:0097630	intrinsic component of omegasome membrane
0.51	GO:0031301	integral component of organelle membrane
0.35	GO:0019013	viral nucleocapsid
0.34	GO:0030529	intracellular ribonucleoprotein complex

tr|R4GKV8|R4GKV8_CHICK
Uncharacterized protein
Search

0.92	GA binding protein transcription factor beta subunit 1 transcript variant gamma-2

0.75	GO:0045944	positive regulation of transcription by RNA polymerase II
0.38	GO:0006351	transcription, DNA-templated

0.76	GO:0044212	transcription regulatory region DNA binding
0.72	GO:0046982	protein heterodimerization activity
0.65	GO:0042803	protein homodimerization activity
0.51	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.54	GO:0036464	cytoplasmic ribonucleoprotein granule
0.48	GO:0043233	organelle lumen
0.43	GO:0044446	intracellular organelle part

tr|R4GKW1|R4GKW1_CHICK
Hexosyltransferase
Search

CHSY3

0.54	Hexosyltransferase

0.50	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process
0.49	GO:0002063	chondrocyte development
0.49	GO:0030204	chondroitin sulfate metabolic process
0.48	GO:0045880	positive regulation of smoothened signaling pathway
0.48	GO:0009954	proximal/distal pattern formation
0.48	GO:0030279	negative regulation of ossification
0.48	GO:0060349	bone morphogenesis
0.47	GO:0051923	sulfation
0.43	GO:0006024	glycosaminoglycan biosynthetic process
0.42	GO:0044272	sulfur compound biosynthetic process

0.84

GO:0008376

acetylgalactosaminyltransferase activity

0.81	GO:0032580	Golgi cisterna membrane
0.42	GO:0005576	extracellular region
0.34	GO:0030176	integral component of endoplasmic reticulum membrane

0.84

GO:0008376

tr|R4GKX0|R4GKX0_CHICK
Uncharacterized protein
Search

RGS5

0.96	Regulator of G protein signaling 5

0.65	GO:0043547	positive regulation of GTPase activity
0.52	GO:0007186	G-protein coupled receptor signaling pathway
0.46	GO:0009968	negative regulation of signal transduction
0.42	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.35	GO:0007601	visual perception

0.65	GO:0005096	GTPase activator activity
0.35	GO:0005516	calmodulin binding

0.61	GO:0005829	cytosol
0.46	GO:0005886	plasma membrane
0.36	GO:0045121	membrane raft
0.30	GO:0031224	intrinsic component of membrane

tr|R4GKX9|R4GKX9_CHICK
Iodothyronine deiodinase
Search

DIO2

0.77	Type II iodothyronine deiodinase

0.78	GO:0042446	hormone biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.49	GO:0042403	thyroid hormone metabolic process
0.42	GO:0061074	regulation of neural retina development
0.41	GO:0019336	phenol-containing compound catabolic process
0.41	GO:0042447	hormone catabolic process
0.41	GO:0048066	developmental pigmentation
0.40	GO:0045454	cell redox homeostasis
0.40	GO:0042219	cellular modified amino acid catabolic process
0.40	GO:0048589	developmental growth

0.85	GO:0004800	thyroxine 5'-deiodinase activity
0.38	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0008430	selenium binding

0.33	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.85

EC:1.97.1.10

GO:0004800

tr|R4GKY2|R4GKY2_CHICK
Uncharacterized protein
Search

TMEM136

0.48	Transmembrane domain-containing protein (Fragment)

0.34	GO:0006351	transcription, DNA-templated
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.33	GO:0007266	Rho protein signal transduction
0.33	GO:0035023	regulation of Rho protein signal transduction
0.33	GO:0043547	positive regulation of GTPase activity
0.32	GO:0007186	G-protein coupled receptor signaling pathway

0.35	GO:0043565	sequence-specific DNA binding
0.35	GO:0003700	DNA binding transcription factor activity
0.33	GO:0001664	G-protein coupled receptor binding
0.33	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.33	GO:0005096	GTPase activator activity

0.35	GO:0005634	nucleus
0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|R4GKY3|R4GKY3_CHICK
Uncharacterized protein
Search

FEV

0.93	FEV, ETS transcription factor

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0030097	hemopoiesis
0.49	GO:0030154	cell differentiation
0.45	GO:0060348	bone development
0.45	GO:0048518	positive regulation of biological process
0.44	GO:0008015	blood circulation
0.44	GO:0009653	anatomical structure morphogenesis
0.43	GO:0006366	transcription by RNA polymerase II

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.48	GO:0044212	transcription regulatory region DNA binding
0.46	GO:0003690	double-stranded DNA binding
0.43	GO:0003682	chromatin binding
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.43	GO:0031974	membrane-enclosed lumen
0.42	GO:0005829	cytosol
0.40	GO:0044446	intracellular organelle part

tr|R4GKY7|R4GKY7_CHICK
Uncharacterized protein
Search

0.33	GO:0003677	DNA binding
0.32	GO:0046872	metal ion binding

0.68	GO:0005829	cytosol
0.35	GO:0071339	MLL1 complex

tr|R4GKZ9|R4GKZ9_CHICK
Uncharacterized protein
Search

CLEC5A

0.88	Killer cell lectin-like receptor subfamily G member 1

0.45	GO:0060355	positive regulation of cell adhesion molecule production
0.44	GO:0071360	cellular response to exogenous dsRNA
0.44	GO:0034138	toll-like receptor 3 signaling pathway
0.44	GO:0006910	phagocytosis, recognition
0.40	GO:0006955	immune response
0.38	GO:0097323	B cell adhesion
0.36	GO:0042102	positive regulation of T cell proliferation

0.69	GO:0030246	carbohydrate binding
0.44	GO:0030169	low-density lipoprotein particle binding
0.43	GO:0008329	signaling pattern recognition receptor activity
0.35	GO:0036094	small molecule binding
0.33	GO:0046872	metal ion binding

0.51	GO:0005581	collagen trimer
0.38	GO:0009986	cell surface
0.35	GO:0098552	side of membrane
0.34	GO:0044459	plasma membrane part
0.30	GO:0016021	integral component of membrane

tr|R4GL01|R4GL01_CHICK
Uncharacterized protein
Search

tr|R4GL05|R4GL05_CHICK
Uncharacterized protein
Search

0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0032553	ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0036064	ciliary basal body
0.30	GO:0031224	intrinsic component of membrane

tr|R4GL06|R4GL06_CHICK
Uncharacterized protein
Search

0.22	Threonylcarbamoyl-AMP synthase

0.44	GO:0002949	tRNA threonylcarbamoyladenosine modification
0.43	GO:0006450	regulation of translational fidelity

0.75	GO:0003725	double-stranded RNA binding
0.42	GO:0000049	tRNA binding
0.40	GO:0016779	nucleotidyltransferase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.40

EC:2.7.7

GO:0016779

tr|R4GL09|R4GL09_CHICK
Uncharacterized protein
Search

0.55	Mannose receptor C-type 1

0.43	GO:0071353	cellular response to interleukin-4
0.42	GO:0071346	cellular response to interferon-gamma
0.42	GO:0071222	cellular response to lipopolysaccharide
0.39	GO:0006898	receptor-mediated endocytosis
0.39	GO:0007165	signal transduction

0.43	GO:0005537	mannose binding
0.41	GO:0004888	transmembrane signaling receptor activity

0.41	GO:0010008	endosome membrane
0.40	GO:0009986	cell surface
0.37	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|R4GL10|R4GL10_CHICK
Uncharacterized protein
Search

RNF144A

0.58	RING-type E3 ubiquitin transferase

0.72	GO:0016567	protein ubiquitination
0.50	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.47	GO:0006511	ubiquitin-dependent protein catabolic process
0.41	GO:0043066	negative regulation of apoptotic process
0.34	GO:0051607	defense response to virus
0.33	GO:0006915	apoptotic process

0.73	GO:0004842	ubiquitin-protein transferase activity
0.53	GO:0046872	metal ion binding
0.51	GO:0016874	ligase activity
0.50	GO:0031624	ubiquitin conjugating enzyme binding
0.47	GO:0061659	ubiquitin-like protein ligase activity
0.33	GO:0051536	iron-sulfur cluster binding

0.49	GO:0005794	Golgi apparatus
0.47	GO:0000151	ubiquitin ligase complex
0.38	GO:0031090	organelle membrane
0.38	GO:0044446	intracellular organelle part
0.37	GO:0005739	mitochondrion
0.37	GO:0031975	envelope
0.35	GO:0031410	cytoplasmic vesicle
0.35	GO:0005811	lipid droplet
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0098805	whole membrane

0.51	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

tr|R4GL11|R4GL11_CHICK
Uncharacterized protein
Search

SCRT1

0.89	Zinc finger transcription factor

0.47	GO:2001222	regulation of neuron migration
0.45	GO:0000122	negative regulation of transcription by RNA polymerase II
0.38	GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator
0.38	GO:2000177	regulation of neural precursor cell proliferation
0.37	GO:0043523	regulation of neuron apoptotic process
0.33	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.32	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.32	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.39	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.32	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.32	GO:0046872	metal ion binding
0.32	GO:0005515	protein binding

0.40	GO:0005634	nucleus
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.32	GO:0005694	chromosome

tr|R4GL18|R4GL18_CHICK
Uncharacterized protein
Search

RD3L

0.97	Retinal degeneration 3-like

tr|R4GL26|R4GL26_CHICK
Uncharacterized protein
Search

0.60	Angiopoietin-4

0.69	GO:0048014	Tie signaling pathway
0.62	GO:0001525	angiogenesis
0.54	GO:2000352	negative regulation of endothelial cell apoptotic process
0.52	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.52	GO:0003018	vascular process in circulatory system
0.51	GO:0007596	blood coagulation
0.51	GO:2000446	regulation of macrophage migration inhibitory factor signaling pathway
0.51	GO:0031589	cell-substrate adhesion
0.51	GO:0008015	blood circulation
0.51	GO:0030210	heparin biosynthetic process

0.66	GO:0030971	receptor tyrosine kinase binding
0.48	GO:0030674	protein binding, bridging
0.43	GO:0050839	cell adhesion molecule binding
0.38	GO:0005198	structural molecule activity
0.36	GO:0030246	carbohydrate binding
0.35	GO:0008233	peptidase activity
0.35	GO:0005172	vascular endothelial growth factor receptor binding
0.35	GO:0008061	chitin binding
0.34	GO:0016504	peptidase activator activity
0.33	GO:0005044	scavenger receptor activity

0.51	GO:0005615	extracellular space
0.48	GO:0005902	microvillus
0.47	GO:0098857	membrane microdomain
0.45	GO:0031091	platelet alpha granule
0.43	GO:0009897	external side of plasma membrane
0.42	GO:0005938	cell cortex
0.40	GO:0043234	protein complex
0.36	GO:1903561	extracellular vesicle
0.34	GO:0034774	secretory granule lumen
0.34	GO:0005788	endoplasmic reticulum lumen

0.35

GO:0008233

tr|R4GL30|R4GL30_CHICK
Uncharacterized protein
Search

BAG2

0.91	BCL2 associated athanogene 2

0.69	GO:0050790	regulation of catalytic activity
0.48	GO:0006457	protein folding
0.47	GO:0019538	protein metabolic process

0.79	GO:0000774	adenyl-nucleotide exchange factor activity
0.77	GO:0051087	chaperone binding
0.61	GO:0042802	identical protein binding

tr|R4GL34|R4GL34_CHICK
Uncharacterized protein
Search

TPGS1

0.97	Tubulin polyglutamylase complex subunit 1

0.85	GO:0007288	sperm axoneme assembly
0.84	GO:0018095	protein polyglutamylation
0.80	GO:0030534	adult behavior
0.78	GO:0051648	vesicle localization
0.75	GO:0007268	chemical synaptic transmission
0.47	GO:2000403	positive regulation of lymphocyte migration
0.45	GO:0007160	cell-matrix adhesion
0.44	GO:0007229	integrin-mediated signaling pathway
0.42	GO:0007275	multicellular organism development

0.86	GO:0070740	tubulin-glutamic acid ligase activity
0.72	GO:0008017	microtubule binding
0.48	GO:0098640	integrin binding involved in cell-matrix adhesion

0.76	GO:0005813	centrosome
0.45	GO:0030425	dendrite
0.45	GO:0030424	axon
0.44	GO:0031514	motile cilium
0.43	GO:0005874	microtubule
0.38	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.86

EC:6.3.2

GO:0070740

tr|R4GL36|R4GL36_CHICK
Uncharacterized protein
Search

PGC

0.94	Progastricsin

0.61	GO:0006508	proteolysis
0.54	GO:0002803	positive regulation of antibacterial peptide production
0.48	GO:0006914	autophagy
0.45	GO:0030163	protein catabolic process
0.44	GO:0007586	digestion

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity

0.47	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

tr|R4GL39|R4GL39_CHICK
Uncharacterized protein
Search

tr|R4GL41|R4GL41_CHICK
Uncharacterized protein
Search

ANKRD27

0.78	ankyrin repeat domain-containing protein 27

0.86	GO:0035544	negative regulation of SNARE complex assembly
0.86	GO:1990126	retrograde transport, endosome to plasma membrane
0.86	GO:0045022	early endosome to late endosome transport
0.86	GO:0035646	endosome to melanosome transport
0.85	GO:0050775	positive regulation of dendrite morphogenesis
0.76	GO:0048812	neuron projection morphogenesis
0.66	GO:0065009	regulation of molecular function

0.82	GO:0000149	SNARE binding
0.81	GO:0017137	Rab GTPase binding
0.75	GO:0005085	guanyl-nucleotide exchange factor activity

0.87	GO:0097422	tubular endosome
0.83	GO:0042470	melanosome
0.81	GO:0005770	late endosome
0.81	GO:0005769	early endosome
0.79	GO:0005764	lysosome
0.77	GO:0030133	transport vesicle
0.75	GO:0043005	neuron projection
0.69	GO:0005829	cytosol
0.56	GO:0005886	plasma membrane

tr|R4GL42|R4GL42_CHICK
Uncharacterized protein
Search

SREK1IP1

0.97	SREK1 interacting protein 1

0.38	GO:0008380	RNA splicing
0.37	GO:0006397	mRNA processing
0.35	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0007283	spermatogenesis
0.33	GO:0019991	septate junction assembly

0.62	GO:0008270	zinc ion binding
0.50	GO:0003676	nucleic acid binding
0.35	GO:0008502	melatonin receptor activity
0.33	GO:0005515	protein binding

0.33	GO:0005918	septate junction
0.32	GO:0005634	nucleus
0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|R4GL44|R4GL44_CHICK
Uncharacterized protein
Search

MC3R

0.97	Melanocortin 3 receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.54	GO:0019933	cAMP-mediated signaling
0.53	GO:0060259	regulation of feeding behavior
0.53	GO:0045475	locomotor rhythm
0.52	GO:0032922	circadian regulation of gene expression
0.40	GO:0042309	homoiothermy
0.39	GO:0055078	sodium ion homeostasis
0.38	GO:0002027	regulation of heart rate
0.38	GO:0008217	regulation of blood pressure
0.35	GO:0030819	positive regulation of cAMP biosynthetic process

0.84	GO:0004977	melanocortin receptor activity
0.54	GO:0042923	neuropeptide binding
0.39	GO:0017046	peptide hormone binding
0.34	GO:0005515	protein binding

0.54	GO:0005886	plasma membrane
0.37	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

tr|R4GL52|R4GL52_CHICK
Uncharacterized protein
Search

MPEG1

0.97	Macrophage expressed gene 1

0.38	GO:0042742	defense response to bacterium
0.33	GO:0007264	small GTPase mediated signal transduction
0.33	GO:0065009	regulation of molecular function

0.33

GO:0005085

guanyl-nucleotide exchange factor activity

0.31	GO:0005622	intracellular
0.30	GO:0044425	membrane part

tr|R4GL56|R4GL56_CHICK
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|R4GL66|R4GL66_CHICK
60S ribosomal protein L29
Search

RPL29

0.39	60S ribosomal protein L29

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.36	GO:0035264	multicellular organism growth
0.36	GO:0031589	cell-substrate adhesion
0.35	GO:0008283	cell proliferation
0.35	GO:0007566	embryo implantation
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0007568	aging

0.64	GO:0003735	structural constituent of ribosome
0.45	GO:0045296	cadherin binding
0.37	GO:0008201	heparin binding
0.34	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.33	GO:0003723	RNA binding
0.33	GO:0016301	kinase activity

0.61	GO:0005840	ribosome
0.48	GO:0044445	cytosolic part
0.42	GO:0044446	intracellular organelle part
0.36	GO:0005844	polysome
0.35	GO:0019898	extrinsic component of membrane
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:1902493	acetyltransferase complex
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle

0.34

EC:3.1.3

GO:0017017

tr|R4GL67|R4GL67_CHICK
Uncharacterized protein
Search

PLPPR4

0.72	phospholipid phosphatase-related protein type 4 isoform X1

0.71	GO:0046839	phospholipid dephosphorylation
0.66	GO:0007409	axonogenesis
0.51	GO:0006644	phospholipid metabolic process
0.51	GO:0048839	inner ear development
0.47	GO:0007165	signal transduction

0.78	GO:0042577	lipid phosphatase activity
0.62	GO:0008195	phosphatidate phosphatase activity
0.35	GO:0005515	protein binding

0.60

GO:0005887

integral component of plasma membrane

0.62

EC:3.1.3.4

GO:0008195

tr|R4GL69|R4GL69_CHICK
Uncharacterized protein
Search

CCDC59

0.91	Thyroid transcription factor 1-associated protein 26

0.52

GO:0007156

homophilic cell adhesion via plasma membrane adhesion molecules

0.54	GO:0046983	protein dimerization activity
0.48	GO:0005509	calcium ion binding

0.42	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|R4GL74|R4GL74_CHICK
Uncharacterized protein
Search

MCF2L

0.79	Guanine nucleotide exchange factor DBS

0.78	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.62	GO:0035556	intracellular signal transduction
0.36	GO:0006508	proteolysis

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.39	GO:0035091	phosphatidylinositol binding
0.37	GO:0005509	calcium ion binding
0.37	GO:0004252	serine-type endopeptidase activity

0.45	GO:0005622	intracellular
0.37	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0004252

tr|R4GL75|R4GL75_CHICK
Uncharacterized protein
Search

SLITRK5

0.91	Leucine-rich repeat-containing protein 11

0.59	GO:0051965	positive regulation of synapse assembly
0.59	GO:0007625	grooming behavior
0.58	GO:0021756	striatum development
0.56	GO:0007409	axonogenesis
0.56	GO:0048813	dendrite morphogenesis
0.55	GO:0043588	skin development
0.55	GO:0030534	adult behavior
0.54	GO:0072358	cardiovascular system development
0.53	GO:0007268	chemical synaptic transmission
0.52	GO:0009410	response to xenobiotic stimulus

0.57	GO:0043235	receptor complex
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|R4GL80|R4GL80_CHICK
Uncharacterized protein
Search

COASY

0.87	CoA synthase

0.75	GO:0015937	coenzyme A biosynthetic process
0.57	GO:0016310	phosphorylation

0.79	GO:0004140	dephospho-CoA kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0004595	pantetheine-phosphate adenylyltransferase activity

0.79	EC:2.7.1.24	GO:0004140
0.79	KEGG:R00130	GO:0004140

tr|R4GL82|R4GL82_CHICK
Uncharacterized protein
Search

CMC1

0.67	COX assembly mitochondrial protein homolog

0.34

GO:0046872

metal ion binding

0.61

GO:0005739

mitochondrion

tr|R4GL85|R4GL85_CHICK
Uncharacterized protein
Search

COX11

0.94	Cytochrome c oxidase assembly protein COX11, mitochondrial

0.58	GO:0033132	negative regulation of glucokinase activity
0.49	GO:0055065	metal ion homeostasis
0.35	GO:0007585	respiratory gaseous exchange
0.34	GO:0008535	respiratory chain complex IV assembly
0.33	GO:1902600	hydrogen ion transmembrane transport
0.33	GO:0022900	electron transport chain
0.33	GO:0006413	translational initiation

0.72	GO:0005507	copper ion binding
0.34	GO:0005515	protein binding
0.33	GO:0015002	heme-copper terminal oxidase activity
0.33	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.33	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0009055	electron transfer activity
0.33	GO:0003743	translation initiation factor activity

0.44	GO:0005739	mitochondrion
0.43	GO:0043234	protein complex
0.35	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:1.9.3

GO:0016676

tr|R4GL87|R4GL87_CHICK
Uncharacterized protein
Search

0.78	Ammonium transporter Rh type B-B

0.77	GO:0072488	ammonium transmembrane transport
0.50	GO:0070634	transepithelial ammonium transport
0.46	GO:0006873	cellular ion homeostasis
0.45	GO:0015695	organic cation transport
0.45	GO:0055080	cation homeostasis
0.44	GO:0098771	inorganic ion homeostasis
0.42	GO:0015670	carbon dioxide transport
0.40	GO:0048821	erythrocyte development
0.39	GO:0048871	multicellular organismal homeostasis
0.37	GO:0015672	monovalent inorganic cation transport

0.77	GO:0008519	ammonium transmembrane transporter activity
0.52	GO:0030506	ankyrin binding
0.43	GO:0042802	identical protein binding
0.41	GO:0022842	narrow pore channel activity
0.36	GO:0015379	potassium:chloride symporter activity
0.34	GO:0022820	potassium ion symporter activity
0.33	GO:0004555	alpha,alpha-trehalase activity

0.46	GO:0016324	apical plasma membrane
0.46	GO:0016323	basolateral plasma membrane
0.45	GO:0005887	integral component of plasma membrane
0.35	GO:0031410	cytoplasmic vesicle
0.35	GO:0014731	spectrin-associated cytoskeleton
0.34	GO:0046658	anchored component of plasma membrane
0.33	GO:0005576	extracellular region

0.33

EC:3.2.1.28

GO:0004555

tr|R4GL88|R4GL88_CHICK
Cellular retinoic acid-binding protein 2
Search

CRABP2

0.95	Cellular retinoic acid-binding protein 2

0.74	GO:0048385	regulation of retinoic acid receptor signaling pathway
0.73	GO:0042573	retinoic acid metabolic process
0.66	GO:0042363	fat-soluble vitamin catabolic process
0.66	GO:0016103	diterpenoid catabolic process
0.57	GO:0048672	positive regulation of collateral sprouting
0.55	GO:0035115	embryonic forelimb morphogenesis
0.55	GO:0072329	monocarboxylic acid catabolic process
0.45	GO:0021575	hindbrain morphogenesis
0.35	GO:0016102	diterpenoid biosynthetic process
0.34	GO:0008544	epidermis development

0.84	GO:0001972	retinoic acid binding
0.45	GO:0019841	retinol binding
0.44	GO:0016918	retinal binding
0.37	GO:0019215	intermediate filament binding
0.34	GO:0030332	cyclin binding
0.34	GO:0005198	structural molecule activity
0.33	GO:0042802	identical protein binding

0.52	GO:0005634	nucleus
0.48	GO:0005829	cytosol
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.37	GO:0005783	endoplasmic reticulum
0.36	GO:0070062	extracellular exosome
0.36	GO:0045111	intermediate filament cytoskeleton
0.35	GO:0070852	cell body fiber
0.35	GO:0099512	supramolecular fiber
0.34	GO:0030424	axon

tr|R4GL89|R4GL89_CHICK
Uncharacterized protein
Search

CBLN2

0.94	Cerebellin 2 precursor

0.81	GO:0051965	positive regulation of synapse assembly
0.72	GO:1900454	positive regulation of long term synaptic depression
0.70	GO:0090394	negative regulation of excitatory postsynaptic potential
0.69	GO:0021684	cerebellar granular layer formation
0.67	GO:0021533	cell differentiation in hindbrain
0.66	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.63	GO:0021953	central nervous system neuron differentiation
0.55	GO:0009306	protein secretion
0.38	GO:0048168	regulation of neuronal synaptic plasticity
0.36	GO:0007268	chemical synaptic transmission

0.58	GO:0042803	protein homodimerization activity
0.35	GO:0003676	nucleic acid binding
0.33	GO:0046872	metal ion binding

0.59	GO:0005615	extracellular space
0.59	GO:0045202	synapse
0.42	GO:0098590	plasma membrane region
0.41	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

tr|R4GL94|R4GL94_CHICK
Hexosyltransferase
Search

CHSY1

0.55	Hexosyltransferase

0.57	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process
0.54	GO:0051216	cartilage development
0.53	GO:0030204	chondroitin sulfate metabolic process
0.52	GO:0045880	positive regulation of smoothened signaling pathway
0.52	GO:0009954	proximal/distal pattern formation
0.52	GO:0030279	negative regulation of ossification
0.52	GO:0009887	animal organ morphogenesis
0.50	GO:0060348	bone development
0.50	GO:0051923	sulfation
0.47	GO:0048468	cell development

0.85	GO:0008376	acetylgalactosaminyltransferase activity
0.40	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity
0.36	GO:0008378	galactosyltransferase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0004252	serine-type endopeptidase activity

0.81	GO:0032580	Golgi cisterna membrane
0.44	GO:0005576	extracellular region
0.36	GO:0030176	integral component of endoplasmic reticulum membrane

0.85

GO:0008376

tr|R4GL99|R4GL99_CHICK
Transcription factor MafA
Search

0.77	LOW QUALITY PROTEIN: transcription factor MafA

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0006351	transcription, DNA-templated
0.50	GO:0007263	nitric oxide mediated signal transduction
0.49	GO:0030073	insulin secretion
0.48	GO:0009749	response to glucose
0.44	GO:1902680	positive regulation of RNA biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0046982	protein heterodimerization activity

0.61

GO:0005634

nucleus

tr|R4GLB3|R4GLB3_CHICK
Proteasome subunit beta type
Search

PSMB2

0.53	Proteasome subunit beta type

0.71	GO:0051603	proteolysis involved in cellular protein catabolic process
0.38	GO:0010243	response to organonitrogen compound
0.37	GO:0014070	response to organic cyclic compound
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia

0.76	GO:0070003	threonine-type peptidase activity
0.64	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding

0.75	GO:0005839	proteasome core complex
0.56	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.45	GO:0005737	cytoplasm
0.43	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

tr|R4GLB5|R4GLB5_CHICK
Uncharacterized protein
Search

0.67	caltractin

0.47	GO:0007099	centriole replication
0.45	GO:0032465	regulation of cytokinesis
0.43	GO:0007283	spermatogenesis
0.43	GO:0006289	nucleotide-excision repair
0.40	GO:0022027	interkinetic nuclear migration
0.39	GO:0060271	cilium assembly
0.36	GO:0051301	cell division
0.35	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.34	GO:0140056	organelle localization by membrane tethering

0.70	GO:0005509	calcium ion binding
0.51	GO:0032795	heterotrimeric G-protein binding
0.47	GO:0031683	G-protein beta/gamma-subunit complex binding
0.42	GO:0008017	microtubule binding

0.49	GO:0005814	centriole
0.49	GO:0071942	XPC complex
0.47	GO:0036064	ciliary basal body
0.45	GO:0032391	photoreceptor connecting cilium
0.44	GO:0005813	centrosome
0.34	GO:0030008	TRAPP complex
0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|R4GLC1|R4GLC1_CHICK
Uncharacterized protein
Search

CDC42SE2

0.97	CDC42 small effector protein 2-A

0.68	GO:0009966	regulation of signal transduction
0.51	GO:0008360	regulation of cell shape
0.49	GO:0006909	phagocytosis
0.48	GO:0007165	signal transduction
0.37	GO:0021555	midbrain-hindbrain boundary morphogenesis
0.36	GO:0006348	chromatin silencing at telomere
0.36	GO:0016573	histone acetylation

0.62	GO:0005198	structural molecule activity
0.38	GO:0005515	protein binding
0.36	GO:0004402	histone acetyltransferase activity

0.55	GO:0005886	plasma membrane
0.50	GO:0005856	cytoskeleton
0.44	GO:0042995	cell projection
0.42	GO:0070062	extracellular exosome
0.40	GO:0005737	cytoplasm
0.36	GO:0000781	chromosome, telomeric region
0.34	GO:0005634	nucleus
0.30	GO:0044425	membrane part

0.36

EC:2.3.1.48

GO:0004402

tr|R4GLC9|R4GLC9_CHICK
Uncharacterized protein
Search

TCF21

0.97	LOW QUALITY PROTEIN: transcription factor 21

0.68	GO:0014707	branchiomeric skeletal muscle development
0.65	GO:0060539	diaphragm development
0.63	GO:0060021	palate development
0.63	GO:0072277	metanephric glomerular capillary formation
0.62	GO:0060435	bronchiole development
0.62	GO:0072162	metanephric mesenchymal cell differentiation
0.62	GO:0060426	lung vasculature development
0.61	GO:0060766	negative regulation of androgen receptor signaling pathway
0.59	GO:0048286	lung alveolus development
0.59	GO:0001658	branching involved in ureteric bud morphogenesis

0.68	GO:0046983	protein dimerization activity
0.62	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.60	GO:0070888	E-box binding
0.59	GO:0043425	bHLH transcription factor binding
0.59	GO:0050681	androgen receptor binding
0.57	GO:0042826	histone deacetylase binding
0.57	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.47	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.34	GO:0003714	transcription corepressor activity

0.49	GO:0005634	nucleus
0.42	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part

tr|R4GLD1|R4GLD1_CHICK
Uncharacterized protein
Search

HUNK

0.91	hormonally up-regulated neu tumor-associated kinase

0.63	GO:0006468	protein phosphorylation
0.40	GO:0035556	intracellular signal transduction
0.33	GO:0007275	multicellular organism development

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.40	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|R4GLD6|R4GLD6_CHICK
Uncharacterized protein
Search

PHF13

0.97	PHD finger protein 13

0.54	GO:0007076	mitotic chromosome condensation
0.44	GO:1901097	negative regulation of autophagosome maturation
0.43	GO:1902902	negative regulation of autophagosome assembly
0.41	GO:0031398	positive regulation of protein ubiquitination
0.38	GO:0006914	autophagy
0.35	GO:0016569	covalent chromatin modification
0.34	GO:0051301	cell division

0.52	GO:0046872	metal ion binding
0.51	GO:0003682	chromatin binding
0.34	GO:0140034	methylation-dependent protein binding
0.34	GO:0042393	histone binding
0.32	GO:0003677	DNA binding

0.45	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.33	GO:0005737	cytoplasm

tr|R4GLE3|R4GLE3_CHICK
Uncharacterized protein
Search

0.66	cyclin-dependent kinase inhibitor 1

0.84	GO:0007050	cell cycle arrest
0.82	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.76	GO:0072331	signal transduction by p53 class mediator
0.70	GO:0007346	regulation of mitotic cell cycle
0.51	GO:0016310	phosphorylation
0.50	GO:0042127	regulation of cell proliferation
0.49	GO:1904030	negative regulation of cyclin-dependent protein kinase activity
0.47	GO:0000082	G1/S transition of mitotic cell cycle
0.46	GO:0030308	negative regulation of cell growth
0.46	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity

0.85	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.54	GO:0016301	kinase activity
0.46	GO:0030332	cyclin binding
0.45	GO:0019901	protein kinase binding
0.44	GO:0032403	protein complex binding
0.43	GO:0030295	protein kinase activator activity
0.42	GO:0031625	ubiquitin protein ligase binding
0.40	GO:0019903	protein phosphatase binding
0.38	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.37	GO:0140096	catalytic activity, acting on a protein

0.61	GO:0005634	nucleus
0.43	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.42	GO:0005829	cytosol
0.41	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex
0.39	GO:0070013	intracellular organelle lumen
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0044446	intracellular organelle part
0.34	GO:0005576	extracellular region
0.33	GO:0005768	endosome
0.30	GO:0016020	membrane

0.38

GO:0016773

tr|R4GLE6|R4GLE6_CHICK
Eukaryotic translation initiation factor 1
Search

EIF1

0.93	Eukaryotic translation initiation factor 1

0.72	GO:0006413	translational initiation
0.47	GO:0006446	regulation of translational initiation
0.44	GO:0009048	dosage compensation by inactivation of X chromosome
0.34	GO:0006886	intracellular protein transport

0.73	GO:0003743	translation initiation factor activity
0.35	GO:0017137	Rab GTPase binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0016787	hydrolase activity

0.41	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.32

GO:0016787

tr|R4GLE8|R4GLE8_CHICK
Claudin
Search

CLDN16

0.64

Claudin

0.41	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.35	GO:0007588	excretion
0.35	GO:0070633	transepithelial transport
0.35	GO:0006811	ion transport
0.35	GO:0051928	positive regulation of calcium ion transport
0.34	GO:0006875	cellular metal ion homeostasis
0.33	GO:0055085	transmembrane transport

0.62	GO:0005198	structural molecule activity
0.38	GO:0042802	identical protein binding
0.34	GO:0015095	magnesium ion transmembrane transporter activity

0.81	GO:0005923	bicellular tight junction
0.55	GO:0005886	plasma membrane
0.37	GO:0098594	mucin granule
0.30	GO:0016021	integral component of membrane

tr|R4GLF2|R4GLF2_CHICK
Uncharacterized protein
Search

ARRDC3

0.90	Arrestin domain-containing protein 3 mRNA

0.60	GO:0031651	negative regulation of heat generation
0.60	GO:0007165	signal transduction
0.60	GO:0090327	negative regulation of locomotion involved in locomotory behavior
0.59	GO:0071879	positive regulation of adrenergic receptor signaling pathway
0.59	GO:0044252	negative regulation of multicellular organismal metabolic process
0.58	GO:0060613	fat pad development
0.56	GO:0001659	temperature homeostasis
0.55	GO:0051443	positive regulation of ubiquitin-protein transferase activity
0.54	GO:0043588	skin development
0.33	GO:0043043	peptide biosynthetic process

0.60	GO:0031699	beta-3 adrenergic receptor binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0003723	RNA binding

0.52	GO:0005768	endosome
0.42	GO:0005886	plasma membrane
0.39	GO:0005764	lysosome
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

tr|R4GLF3|R4GLF3_CHICK
Uncharacterized protein
Search

SAMD5

0.88	Sterile alpha motif domain-containing protein 5

0.70	GO:0007608	sensory perception of smell
0.38	GO:0016192	vesicle-mediated transport

0.30

GO:0016020

membrane

tr|R4GLF5|R4GLF5_CHICK
Uncharacterized protein
Search

SAP30L

0.91	histone deacetylase complex subunit SAP30

0.61	GO:0009888	tissue development
0.61	GO:0016575	histone deacetylation
0.60	GO:0000122	negative regulation of transcription by RNA polymerase II
0.60	GO:0048513	animal organ development
0.57	GO:0061061	muscle structure development
0.53	GO:0007368	determination of left/right symmetry
0.53	GO:0030154	cell differentiation
0.52	GO:0035239	tube morphogenesis
0.51	GO:0048598	embryonic morphogenesis
0.51	GO:0072359	circulatory system development

0.74	GO:0044378	non-sequence-specific DNA binding, bending
0.71	GO:0010314	phosphatidylinositol-5-phosphate binding
0.67	GO:0031491	nucleosome binding
0.65	GO:0042393	histone binding
0.64	GO:0003712	transcription cofactor activity
0.61	GO:0004407	histone deacetylase activity
0.53	GO:0008270	zinc ion binding
0.48	GO:0070273	phosphatidylinositol-4-phosphate binding
0.48	GO:0032266	phosphatidylinositol-3-phosphate binding
0.33	GO:0016740	transferase activity

0.70	GO:0000118	histone deacetylase complex
0.60	GO:0005730	nucleolus
0.35	GO:0000790	nuclear chromatin

0.61

EC:3.5.1.98

GO:0004407

tr|R4GLG2|R4GLG2_CHICK
Uncharacterized protein
Search

SLC25A20

0.81	Carnitine/acylcarnitine translocase

0.50	GO:1902603	carnitine transmembrane transport
0.46	GO:0006839	mitochondrial transport
0.39	GO:1902616	acyl carnitine transmembrane transport
0.35	GO:1902001	fatty acid transmembrane transport
0.35	GO:0032365	intracellular lipid transport
0.34	GO:0015909	long-chain fatty acid transport
0.32	GO:0006518	peptide metabolic process
0.32	GO:0043604	amide biosynthetic process
0.32	GO:0016310	phosphorylation
0.32	GO:0044267	cellular protein metabolic process

0.50	GO:0005476	carnitine:acyl carnitine antiporter activity
0.50	GO:0015226	carnitine transmembrane transporter activity
0.39	GO:0015227	acyl carnitine transmembrane transporter activity
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0016301	kinase activity

0.48	GO:0005829	cytosol
0.46	GO:0031966	mitochondrial membrane
0.46	GO:0019866	organelle inner membrane
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

tr|R4GLH0|R4GLH0_CHICK
Uncharacterized protein
Search

ESM1

0.97	Endothelial cell specific molecule 1

0.80	GO:0001558	regulation of cell growth
0.62	GO:1902204	positive regulation of hepatocyte growth factor receptor signaling pathway
0.56	GO:0002040	sprouting angiogenesis
0.53	GO:0008284	positive regulation of cell proliferation
0.38	GO:0035988	chondrocyte proliferation
0.38	GO:0001502	cartilage condensation
0.38	GO:0051496	positive regulation of stress fiber assembly
0.38	GO:0032330	regulation of chondrocyte differentiation
0.38	GO:0046330	positive regulation of JNK cascade
0.38	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.84	GO:0005520	insulin-like growth factor binding
0.61	GO:0005171	hepatocyte growth factor receptor binding
0.58	GO:0005178	integrin binding
0.38	GO:0008201	heparin binding
0.37	GO:0008022	protein C-terminus binding
0.34	GO:0004252	serine-type endopeptidase activity
0.33	GO:0008083	growth factor activity
0.33	GO:0001968	fibronectin binding
0.32	GO:0005509	calcium ion binding
0.32	GO:0019904	protein domain specific binding

0.66	GO:0005576	extracellular region
0.33	GO:0005801	cis-Golgi network
0.33	GO:0048471	perinuclear region of cytoplasm
0.32	GO:0005938	cell cortex
0.32	GO:0005829	cytosol
0.31	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0004252

tr|R4GLH5|R4GLH5_CHICK
Uncharacterized protein
Search

DNAL1

0.95	Dynein axonemal light chain 1

0.84	GO:0036158	outer dynein arm assembly
0.37	GO:0035383	thioester metabolic process
0.37	GO:0016973	poly(A)+ mRNA export from nucleus
0.37	GO:0006631	fatty acid metabolic process
0.36	GO:0006732	coenzyme metabolic process
0.34	GO:0006793	phosphorus metabolic process
0.33	GO:0055114	oxidation-reduction process

0.84	GO:0045504	dynein heavy chain binding
0.82	GO:0043014	alpha-tubulin binding
0.49	GO:0003774	motor activity
0.38	GO:0047617	acyl-CoA hydrolase activity
0.37	GO:0030246	carbohydrate binding
0.34	GO:0003723	RNA binding
0.33	GO:0016491	oxidoreductase activity

0.52	GO:0030286	dynein complex
0.50	GO:0005874	microtubule
0.47	GO:0042995	cell projection
0.41	GO:0099568	cytoplasmic region
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.38

EC:3.1.2 EC:3.1.2.20

GO:0047617

tr|R4GLH9|R4GLH9_CHICK
Uncharacterized protein
Search

MAP3K19

0.93	Mitogen-activated protein kinase kinase kinase 19

0.63	GO:0006468	protein phosphorylation
0.50	GO:0031098	stress-activated protein kinase signaling cascade
0.49	GO:0032147	activation of protein kinase activity
0.48	GO:0007346	regulation of mitotic cell cycle
0.47	GO:0042981	regulation of apoptotic process
0.36	GO:0043622	cortical microtubule organization
0.34	GO:0043406	positive regulation of MAP kinase activity
0.34	GO:2000071	regulation of defense response by callose deposition
0.33	GO:0071323	cellular response to chitin
0.33	GO:1900150	regulation of defense response to fungus

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.33	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.33	GO:0004623	phospholipase A2 activity
0.33	GO:0005057	signal transducer activity, downstream of receptor

0.37	GO:0005737	cytoplasm
0.36	GO:0048046	apoplast
0.33	GO:0005874	microtubule
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

EC:1.3.1.74

GO:0032440

tr|R4GLI0|R4GLI0_CHICK
Uncharacterized protein
Search

0.60	Dystrotelin

0.35	GO:0005975	carbohydrate metabolic process
0.34	GO:0055114	oxidation-reduction process
0.33	GO:0006108	malate metabolic process

0.63	GO:0008270	zinc ion binding
0.51	GO:0003779	actin binding
0.36	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.33	GO:0016615	malate dehydrogenase activity

0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:1.1.1

GO:0016616

tr|R4GLI2|R4GLI2_CHICK
GMP reductase
Search

GMPR

0.57	GMP reductase

0.70	GO:0006144	purine nucleobase metabolic process
0.59	GO:0009117	nucleotide metabolic process
0.53	GO:0055114	oxidation-reduction process
0.36	GO:0072522	purine-containing compound biosynthetic process
0.36	GO:0009409	response to cold
0.35	GO:1901293	nucleoside phosphate biosynthetic process
0.35	GO:1901068	guanosine-containing compound metabolic process
0.35	GO:0043094	cellular metabolic compound salvage
0.33	GO:0009126	purine nucleoside monophosphate metabolic process
0.33	GO:0009161	ribonucleoside monophosphate metabolic process

0.82	GO:0003920	GMP reductase activity
0.53	GO:0046872	metal ion binding
0.37	GO:0003938	IMP dehydrogenase activity

0.81	GO:1902560	GMP reductase complex
0.34	GO:0005829	cytosol

0.82	EC:1.7.1.7	GO:0003920
0.82	KEGG:R01134	GO:0003920

tr|R4GLI3|R4GLI3_CHICK
Uncharacterized protein
Search

HOXB2

0.77	Homeobox protein Hox-B2

0.66	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0048857	neural nucleus development
0.48	GO:0048532	anatomical structure arrangement
0.48	GO:0002011	morphogenesis of an epithelial sheet
0.46	GO:0060322	head development
0.44	GO:1902680	positive regulation of RNA biosynthetic process
0.37	GO:0006351	transcription, DNA-templated

0.65	GO:0043565	sequence-specific DNA binding
0.58	GO:0003700	DNA binding transcription factor activity
0.35	GO:0001012	RNA polymerase II regulatory region DNA binding
0.34	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.42	GO:0005829	cytosol
0.42	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|R4GLI9|R4GLI9_CHICK
Uncharacterized protein
Search

NQO2

0.92	Ribosyldihydronicotinamide dehydrogenase quinone

0.57	GO:0022900	electron transport chain
0.44	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.44	GO:0043525	positive regulation of neuron apoptotic process
0.43	GO:2000379	positive regulation of reactive oxygen species metabolic process
0.43	GO:0007613	memory
0.43	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.41	GO:0071466	cellular response to xenobiotic stimulus
0.36	GO:0043086	negative regulation of catalytic activity
0.36	GO:0006979	response to oxidative stress
0.35	GO:0006468	protein phosphorylation

0.86	GO:1905594	resveratrol binding
0.86	GO:1904408	melatonin binding
0.85	GO:0001512	dihydronicotinamide riboside quinone reductase activity
0.82	GO:0031404	chloride ion binding
0.70	GO:0042803	protein homodimerization activity
0.69	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors
0.68	GO:0071949	FAD binding
0.59	GO:0008270	zinc ion binding
0.58	GO:0009055	electron transfer activity
0.45	GO:0003955	NAD(P)H dehydrogenase (quinone) activity

0.65	GO:0005654	nucleoplasm
0.64	GO:0005829	cytosol
0.42	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.85

EC:1.10.99.2

GO:0001512

tr|R4GLJ0|R4GLJ0_CHICK
Uncharacterized protein
Search

TM4SF1

0.90	Transmembrane 4 L six family member 1

0.34

GO:0055085

transmembrane transport

0.34	GO:0022857	transmembrane transporter activity
0.33	GO:0005515	protein binding

0.41

GO:0005887

integral component of plasma membrane

tr|R4GLJ2|R4GLJ2_CHICK
MICOS complex subunit MIC13
Search

C19ORF70

0.87	MICOS complex subunit MIC13

0.42

GO:0042407

cristae formation

0.83	GO:0061617	MICOS complex
0.49	GO:0005654	nucleoplasm
0.42	GO:0044284	mitochondrial crista junction

tr|R4GLJ4|R4GLJ4_CHICK
Uncharacterized protein
Search

TM6SF2

0.94	Transmembrane 6 superfamily member 2

0.51	GO:0019216	regulation of lipid metabolic process
0.35	GO:0007155	cell adhesion
0.34	GO:0006396	RNA processing
0.33	GO:0006629	lipid metabolic process
0.33	GO:0032259	methylation

0.36	GO:0005540	hyaluronic acid binding
0.34	GO:0003723	RNA binding
0.32	GO:0005515	protein binding

0.54	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.51	GO:0005765	lysosomal membrane
0.48	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005845	mRNA cap binding complex
0.30	GO:0031224	intrinsic component of membrane

tr|R4GLJ6|R4GLJ6_CHICK
Uncharacterized protein
Search

VHL

0.95	von Hippel-Lindau disease tumor suppressor

0.83	GO:1902072	negative regulation of hypoxia-inducible factor-1alpha signaling pathway
0.82	GO:0048877	homeostasis of number of retina cells
0.80	GO:0061073	ciliary body morphogenesis
0.79	GO:0070244	negative regulation of thymocyte apoptotic process
0.79	GO:0061072	iris morphogenesis
0.79	GO:0045602	negative regulation of endothelial cell differentiation
0.79	GO:0003310	pancreatic A cell differentiation
0.76	GO:0043534	blood vessel endothelial cell migration
0.76	GO:0048069	eye pigmentation
0.76	GO:0003309	type B pancreatic cell differentiation

0.67	GO:0032403	protein complex binding
0.63	GO:0061630	ubiquitin protein ligase activity
0.54	GO:0008134	transcription factor binding
0.53	GO:0019899	enzyme binding

0.76	GO:0031462	Cul2-RING ubiquitin ligase complex
0.69	GO:0030891	VCB complex
0.67	GO:0005929	cilium
0.65	GO:0005654	nucleoplasm
0.64	GO:0005730	nucleolus
0.46	GO:0005829	cytosol
0.44	GO:0031209	SCAR complex
0.43	GO:0005739	mitochondrion
0.39	GO:0005667	transcription factor complex
0.39	GO:0005783	endoplasmic reticulum

tr|R4GLJ9|R4GLJ9_CHICK
Uncharacterized protein
Search

0.80	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.77	GO:0007605	sensory perception of sound
0.71	GO:0007399	nervous system development
0.69	GO:0030154	cell differentiation
0.68	GO:0006397	mRNA processing
0.46	GO:0008380	RNA splicing
0.41	GO:0048857	neural nucleus development
0.40	GO:0071695	anatomical structure maturation
0.39	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.39	GO:0060322	head development

0.72

GO:0003729

mRNA binding

0.60	GO:0005634	nucleus
0.39	GO:0034708	methyltransferase complex
0.37	GO:0044446	intracellular organelle part
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

tr|R4GLK3|R4GLK3_CHICK
Uncharacterized protein
Search

PSMD4

0.90	26S proteasome non-ATPase regulatory subunit 4

0.66	GO:0006511	ubiquitin-dependent protein catabolic process
0.44	GO:0043248	proteasome assembly
0.43	GO:0010498	proteasomal protein catabolic process
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.36	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.36	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.36	GO:0038095	Fc-epsilon receptor signaling pathway
0.36	GO:1902036	regulation of hematopoietic stem cell differentiation
0.36	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia

0.45	GO:0031593	polyubiquitin modification-dependent protein binding
0.37	GO:0042802	identical protein binding
0.37	GO:0008134	transcription factor binding
0.34	GO:0003723	RNA binding
0.33	GO:0003735	structural constituent of ribosome

0.75	GO:0008540	proteasome regulatory particle, base subcomplex
0.48	GO:0005829	cytosol
0.47	GO:0005654	nucleoplasm
0.33	GO:0005840	ribosome

tr|R4GLL2|R4GLL2_CHICK
Keratin
Search

0.75

Keratin

0.71

GO:0007010

cytoskeleton organization

0.77

GO:0005200

structural constituent of cytoskeleton

0.79	GO:0005882	intermediate filament
0.30	GO:0031224	intrinsic component of membrane

tr|R4GLL3|R4GLL3_CHICK
Uncharacterized protein
Search

GIPC3

0.94	PDZ domain-containing protein GIPC3

0.72	GO:0014047	glutamate secretion
0.69	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.68	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.67	GO:0043542	endothelial cell migration
0.66	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.66	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
0.66	GO:0048167	regulation of synaptic plasticity
0.65	GO:0032467	positive regulation of cytokinesis
0.63	GO:0031647	regulation of protein stability
0.62	GO:0007268	chemical synaptic transmission

0.67	GO:0017022	myosin binding
0.63	GO:0045296	cadherin binding
0.60	GO:0042803	protein homodimerization activity
0.59	GO:0003779	actin binding
0.57	GO:0005102	receptor binding
0.45	GO:0030165	PDZ domain binding
0.40	GO:0004957	prostaglandin E receptor activity
0.40	GO:0004707	MAP kinase activity
0.39	GO:0051082	unfolded protein binding
0.39	GO:0003677	DNA binding

0.68	GO:0043198	dendritic shaft
0.67	GO:0043197	dendritic spine
0.65	GO:0031982	vesicle
0.63	GO:0098793	presynapse
0.60	GO:0005938	cell cortex
0.56	GO:0005829	cytosol
0.55	GO:0012505	endomembrane system
0.51	GO:0031090	organelle membrane
0.47	GO:0043229	intracellular organelle
0.44	GO:0005903	brush border

0.40	EC:2.7.11.24	GO:0004707
0.40	KEGG:R00162	GO:0004707

tr|R4GLL9|R4GLL9_CHICK
Uncharacterized protein
Search

RNF24

0.97	Ring finger protein 24

0.48	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.47	GO:0000209	protein polyubiquitination
0.46	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

0.57	GO:0008270	zinc ion binding
0.46	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0005515	protein binding

0.50	GO:0005794	Golgi apparatus
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

tr|R4GLM3|R4GLM3_CHICK
Uncharacterized protein
Search

RAB38

0.95	Ras-related protein Rab-38

0.67	GO:0016192	vesicle-mediated transport
0.46	GO:0032438	melanosome organization
0.44	GO:0035646	endosome to melanosome transport
0.44	GO:0090382	phagosome maturation
0.42	GO:0051452	intracellular pH reduction
0.40	GO:0007005	mitochondrion organization
0.40	GO:0070925	organelle assembly
0.40	GO:0072657	protein localization to membrane
0.39	GO:0060155	platelet dense granule organization
0.35	GO:0043687	post-translational protein modification

0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0036461	BLOC-2 complex binding
0.45	GO:0035651	AP-3 adaptor complex binding
0.44	GO:0035650	AP-1 adaptor complex binding
0.44	GO:0030742	GTP-dependent protein binding
0.38	GO:0035612	AP-2 adaptor complex binding

0.77	GO:0005802	trans-Golgi network
0.70	GO:0031982	vesicle
0.42	GO:0044233	ER-mitochondrion membrane contact site
0.40	GO:0005764	lysosome
0.40	GO:0098805	whole membrane
0.40	GO:0098588	bounding membrane of organelle
0.38	GO:0005739	mitochondrion
0.37	GO:0005783	endoplasmic reticulum
0.37	GO:0005829	cytosol
0.35	GO:0031974	membrane-enclosed lumen

tr|R4GLN9|R4GLN9_CHICK
Keratin
Search

0.85	Feather keratin 2

0.71

GO:0007010

cytoskeleton organization

0.77

GO:0005200

structural constituent of cytoskeleton

0.79

GO:0005882

intermediate filament

tr|R4GLP0|R4GLP0_CHICK
Uncharacterized protein
Search

COX7C

0.94	Cytochrome c oxidase polypeptide VIIc

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.44	GO:0006119	oxidative phosphorylation
0.44	GO:0009060	aerobic respiration

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.53	GO:0005751	mitochondrial respiratory chain complex IV
0.30	GO:0031224	intrinsic component of membrane

0.65

EC:1.9.3

GO:0016676

tr|R4GLP1|R4GLP1_CHICK
Uncharacterized protein
Search

DIRAS1

0.91	DIRAS family GTPase 1

0.61	GO:0007165	signal transduction
0.50	GO:0061551	trigeminal ganglion development
0.45	GO:0048666	neuron development
0.38	GO:0043406	positive regulation of MAP kinase activity

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0051019	mitogen-activated protein kinase binding

0.50

GO:0005886

plasma membrane

tr|R4GLP3|R4GLP3_CHICK
Uncharacterized protein
Search

CECR6

0.93	Cat eye syndrome critical region protein 6

0.36	GO:0043043	peptide biosynthetic process
0.35	GO:0044267	cellular protein metabolic process
0.34	GO:0010467	gene expression
0.34	GO:0009059	macromolecule biosynthetic process

0.39	GO:0008097	5S rRNA binding
0.36	GO:0003735	structural constituent of ribosome

0.36	GO:0005840	ribosome
0.30	GO:0044425	membrane part

tr|R4GLP5|R4GLP5_CHICK
Uncharacterized protein
Search

0.58	Integrator complex subunit 3

0.79	GO:0010212	response to ionizing radiation
0.77	GO:0016180	snRNA processing
0.76	GO:0007093	mitotic cell cycle checkpoint
0.62	GO:0006281	DNA repair
0.44	GO:0006182	cGMP biosynthetic process
0.41	GO:0042795	snRNA transcription by RNA polymerase II
0.39	GO:0006468	protein phosphorylation
0.39	GO:0035556	intracellular signal transduction

0.44	GO:0004383	guanylate cyclase activity
0.39	GO:0004672	protein kinase activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005515	protein binding

0.84	GO:0070876	SOSS complex
0.78	GO:0032039	integrator complex
0.68	GO:0005730	nucleolus
0.47	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.44

EC:4.6.1.2

GO:0004383

tr|R4GLQ3|R4GLQ3_CHICK
Uncharacterized protein
Search

TRMT10B

0.93	RNA (Guanine-9-)-methyltransferase domain-containing protein 3

0.60	GO:0032259	methylation
0.49	GO:0006400	tRNA modification
0.40	GO:0044260	cellular macromolecule metabolic process

0.61	GO:0008168	methyltransferase activity
0.48	GO:0140101	catalytic activity, acting on a tRNA

0.48	GO:0005829	cytosol
0.35	GO:0005739	mitochondrion
0.34	GO:0005856	cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

0.61

GO:0008168

tr|R4GLQ9|R4GLQ9_CHICK
Keratin
Search

0.82	Feather beta keratin

0.71

GO:0007010

cytoskeleton organization

0.77

GO:0005200

structural constituent of cytoskeleton

0.79

GO:0005882

intermediate filament

tr|R4GLR2|R4GLR2_CHICK
Cyclin-dependent kinase inhibitor 1D
Search

0.71	Cyclin-dependent kinase inhibitor 1

0.84	GO:0007050	cell cycle arrest
0.82	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.77	GO:0072331	signal transduction by p53 class mediator
0.71	GO:0007346	regulation of mitotic cell cycle
0.51	GO:0016310	phosphorylation
0.50	GO:0042127	regulation of cell proliferation
0.47	GO:1904030	negative regulation of cyclin-dependent protein kinase activity
0.45	GO:0000082	G1/S transition of mitotic cell cycle
0.45	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
0.44	GO:0030308	negative regulation of cell growth

0.85	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.54	GO:0016301	kinase activity
0.44	GO:0030332	cyclin binding
0.43	GO:0019901	protein kinase binding
0.43	GO:0032403	protein complex binding
0.41	GO:0019903	protein phosphatase binding
0.40	GO:0030295	protein kinase activator activity
0.39	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.36	GO:0030544	Hsp70 protein binding

0.61	GO:0005634	nucleus
0.41	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex
0.41	GO:0005829	cytosol
0.40	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.38	GO:0070013	intracellular organelle lumen
0.36	GO:0044446	intracellular organelle part
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0005768	endosome
0.33	GO:0005576	extracellular region

0.36

GO:0016773

tr|R4GLR8|R4GLR8_CHICK
Keratin
Search

0.68	Feather beta keratin

0.71

GO:0007010

cytoskeleton organization

0.77

GO:0005200

structural constituent of cytoskeleton

0.79

GO:0005882

intermediate filament

tr|R4GLS0|R4GLS0_CHICK
Uncharacterized protein
Search

0.80	Adherens junction-associated protein 1

0.65	GO:0030860	regulation of polarized epithelial cell differentiation
0.61	GO:0001953	negative regulation of cell-matrix adhesion
0.60	GO:0061045	negative regulation of wound healing
0.41	GO:0007155	cell adhesion

0.59	GO:0008013	beta-catenin binding
0.54	GO:0032403	protein complex binding
0.33	GO:0003676	nucleic acid binding

0.63	GO:0044214	spanning component of plasma membrane
0.60	GO:0044291	cell-cell contact zone
0.59	GO:0005913	cell-cell adherens junction
0.55	GO:0009898	cytoplasmic side of plasma membrane
0.55	GO:0009986	cell surface
0.43	GO:0016323	basolateral plasma membrane
0.43	GO:0016324	apical plasma membrane

tr|R4GLS1|R4GLS1_CHICK
Uncharacterized protein
Search

CISD2

0.97	CDGSH iron-sulfur domain-containing protein 2

0.56	GO:0000422	autophagy of mitochondrion
0.55	GO:0010259	multicellular organism aging
0.51	GO:0010506	regulation of autophagy
0.33	GO:0106004	tRNA (guanine-N7)-methylation

0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.52	GO:0042803	protein homodimerization activity
0.37	GO:0046872	metal ion binding
0.34	GO:0003723	RNA binding
0.33	GO:0008176	tRNA (guanine-N7-)-methyltransferase activity

0.56	GO:0043231	intracellular membrane-bounded organelle
0.52	GO:0031968	organelle outer membrane
0.50	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.48	GO:0031984	organelle subcompartment
0.43	GO:0043234	protein complex
0.42	GO:0044444	cytoplasmic part
0.30	GO:0016021	integral component of membrane

0.33

EC:2.1.1.33

GO:0008176

tr|R4GLS4|R4GLS4_CHICK
Uncharacterized protein
Search

TMEM144

0.97	Transmembrane protein 144

0.72	GO:0034219	carbohydrate transmembrane transport
0.32	GO:0007186	G-protein coupled receptor signaling pathway

0.71	GO:0015144	carbohydrate transmembrane transporter activity
0.32	GO:0016500	protein-hormone receptor activity
0.32	GO:0004930	G-protein coupled receptor activity

0.30

GO:0044425

membrane part

tr|R4GLS6|R4GLS6_CHICK
Uncharacterized protein
Search

ATF3

0.97	Cyclic AMP-dependent transcription factor ATF-3

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.61	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway
0.57	GO:0035914	skeletal muscle cell differentiation
0.57	GO:0034198	cellular response to amino acid starvation
0.57	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.56	GO:0030968	endoplasmic reticulum unfolded protein response
0.56	GO:0043620	regulation of DNA-templated transcription in response to stress
0.51	GO:0045892	negative regulation of transcription, DNA-templated
0.51	GO:0010604	positive regulation of macromolecule metabolic process
0.51	GO:0045935	positive regulation of nucleobase-containing compound metabolic process

0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0042803	protein homodimerization activity
0.52	GO:0046982	protein heterodimerization activity
0.37	GO:0003682	chromatin binding
0.34	GO:0003714	transcription corepressor activity

0.61	GO:1990622	CHOP-ATF3 complex
0.60	GO:0005634	nucleus
0.48	GO:0043233	organelle lumen
0.44	GO:0043232	intracellular non-membrane-bounded organelle
0.44	GO:0044446	intracellular organelle part
0.39	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

tr|R4GLT4|R4GLT4_CHICK
Uncharacterized protein
Search

SNTB1

0.84	LOW QUALITY PROTEIN: beta-2-syntrophin

0.38	GO:0050808	synapse organization
0.34	GO:0006936	muscle contraction

0.62	GO:0005198	structural molecule activity
0.38	GO:0005516	calmodulin binding
0.37	GO:0003779	actin binding
0.37	GO:0030165	PDZ domain binding
0.34	GO:0003723	RNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0045202	synapse
0.47	GO:0043234	protein complex
0.39	GO:0005737	cytoplasm
0.39	GO:0030054	cell junction
0.37	GO:0031982	vesicle
0.37	GO:0043230	extracellular organelle
0.36	GO:0005856	cytoskeleton
0.36	GO:0044459	plasma membrane part
0.36	GO:0005615	extracellular space
0.36	GO:0099512	supramolecular fiber

tr|R4GLV2|R4GLV2_CHICK
Uncharacterized protein
Search

PDYN

0.76	Proenkephalin-B

0.80	GO:0007218	neuropeptide signaling pathway
0.60	GO:0010469	regulation of receptor activity
0.50	GO:0007600	sensory perception
0.49	GO:0007268	chemical synaptic transmission
0.46	GO:0002118	aggressive behavior
0.46	GO:0001964	startle response
0.46	GO:0001662	behavioral fear response
0.44	GO:0007626	locomotory behavior
0.35	GO:0046928	regulation of neurotransmitter secretion

0.66	GO:0001515	opioid peptide activity
0.56	GO:0031628	opioid receptor binding
0.52	GO:0005184	neuropeptide hormone activity

0.52	GO:0043679	axon terminus
0.51	GO:0005576	extracellular region
0.50	GO:0043025	neuronal cell body
0.50	GO:0030425	dendrite
0.45	GO:0005886	plasma membrane
0.32	GO:0005737	cytoplasm

tr|R4GLV4|R4GLV4_CHICK
Uncharacterized protein
Search

MKI67

0.97	Antigen KI-67 isoform E

tr|R4GLV5|R4GLV5_CHICK
Uncharacterized protein
Search

SREBF1

0.92	Sterol regulatory element binding transcription factor 1

0.56	GO:0003062	regulation of heart rate by chemical signal
0.56	GO:0045542	positive regulation of cholesterol biosynthetic process
0.56	GO:0010867	positive regulation of triglyceride biosynthetic process
0.55	GO:0031065	positive regulation of histone deacetylation
0.54	GO:0042789	mRNA transcription by RNA polymerase II
0.54	GO:0046676	negative regulation of insulin secretion
0.53	GO:0008286	insulin receptor signaling pathway
0.53	GO:0045444	fat cell differentiation
0.53	GO:0009749	response to glucose
0.52	GO:1903146	regulation of autophagy of mitochondrion

0.67	GO:0046983	protein dimerization activity
0.56	GO:0032810	sterol response element binding
0.51	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0004879	nuclear receptor activity
0.50	GO:0019901	protein kinase binding
0.49	GO:0003682	chromatin binding
0.38	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.37	GO:0032403	protein complex binding

0.44	GO:0005634	nucleus
0.40	GO:0012507	ER to Golgi transport vesicle membrane
0.39	GO:0000139	Golgi membrane
0.38	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:0043234	protein complex
0.33	GO:0005829	cytosol
0.33	GO:0031967	organelle envelope
0.30	GO:0016021	integral component of membrane

tr|R4GLV7|R4GLV7_CHICK
Uncharacterized protein
Search

TTF1

0.88	Transcription termination factor 1

0.44	GO:0030154	cell differentiation
0.44	GO:0006363	termination of RNA polymerase I transcription
0.44	GO:0006357	regulation of transcription by RNA polymerase II
0.42	GO:0006361	transcription initiation from RNA polymerase I promoter
0.40	GO:0006338	chromatin remodeling
0.39	GO:0008156	negative regulation of DNA replication
0.37	GO:0000183	chromatin silencing at rDNA
0.33	GO:0044267	cellular protein metabolic process

0.53	GO:0003677	DNA binding
0.49	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.46	GO:0001067	regulatory region nucleic acid binding
0.45	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.40	GO:0003682	chromatin binding
0.34	GO:0005515	protein binding

0.51	GO:0005730	nucleolus
0.49	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.37	GO:0005654	nucleoplasm

tr|R4GLV8|R4GLV8_CHICK
Uncharacterized protein
Search

0.88	Protocadherin gamma subfamily C, 3

0.77	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.49	GO:0007267	cell-cell signaling
0.49	GO:0007399	nervous system development
0.45	GO:0050808	synapse organization
0.41	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.36	GO:0060989	lipid tube assembly involved in organelle fusion
0.35	GO:0008333	endosome to lysosome transport
0.34	GO:0007283	spermatogenesis

0.69	GO:0005509	calcium ion binding
0.36	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.55	GO:0005886	plasma membrane
0.37	GO:0005911	cell-cell junction
0.37	GO:0070062	extracellular exosome
0.36	GO:0030426	growth cone
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

tr|R4GLW2|R4GLW2_CHICK
Uncharacterized protein
Search

APPL2

0.92	DCC-interacting protein 13-beta

0.75	GO:0008283	cell proliferation
0.58	GO:0007049	cell cycle
0.46	GO:0007165	signal transduction

0.58

GO:0005515

protein binding

0.82	GO:0090545	CHD-type complex
0.79	GO:0090568	nuclear transcriptional repressor complex
0.78	GO:0000118	histone deacetylase complex
0.74	GO:0010008	endosome membrane
0.68	GO:0005769	early endosome
0.57	GO:0070062	extracellular exosome

tr|R4GLW7|R4GLW7_CHICK
Kinase
Search

IP6K3

0.50

Kinase

0.83	GO:0032958	inositol phosphate biosynthetic process
0.57	GO:0016310	phosphorylation
0.51	GO:0046488	phosphatidylinositol metabolic process
0.43	GO:0036211	protein modification process
0.41	GO:0030308	negative regulation of cell growth
0.41	GO:0044267	cellular protein metabolic process
0.40	GO:0043065	positive regulation of apoptotic process
0.40	GO:0030258	lipid modification

0.60	GO:0016301	kinase activity
0.50	GO:0016776	phosphotransferase activity, phosphate group as acceptor

0.45	GO:0005634	nucleus
0.40	GO:0030054	cell junction
0.39	GO:0031974	membrane-enclosed lumen
0.38	GO:0005737	cytoplasm
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0044446	intracellular organelle part

0.50

EC:2.7.4

GO:0016776

tr|R4GLX1|R4GLX1_CHICK
Gap junction protein
Search

GJA9

0.58	Gap junction protein (Fragment)

0.60	GO:0007154	cell communication
0.47	GO:0050908	detection of light stimulus involved in visual perception
0.46	GO:0007416	synapse assembly
0.44	GO:0007276	gamete generation
0.39	GO:0055085	transmembrane transport

0.51	GO:0005243	gap junction channel activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003677	DNA binding

0.83	GO:0005922	connexin complex
0.30	GO:0016021	integral component of membrane

tr|R4GLX2|R4GLX2_CHICK
Uncharacterized protein
Search

ARL9

0.91	ADP ribosylation factor like GTPase 9

0.37	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.36	GO:0051519	activation of bipolar cell growth
0.36	GO:0061389	regulation of direction of cell growth
0.36	GO:0061171	establishment of bipolar cell polarity
0.35	GO:0035845	photoreceptor cell outer segment organization
0.34	GO:0060271	cilium assembly
0.33	GO:0000042	protein targeting to Golgi
0.33	GO:0043001	Golgi to plasma membrane protein transport
0.33	GO:0034976	response to endoplasmic reticulum stress
0.33	GO:0016310	phosphorylation

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0008312	7S RNA binding
0.34	GO:0003951	NAD+ kinase activity
0.33	GO:0016874	ligase activity
0.32	GO:0016787	hydrolase activity
0.32	GO:0016491	oxidoreductase activity

0.45	GO:0005622	intracellular
0.35	GO:0000935	division septum
0.35	GO:0051286	cell tip
0.35	GO:1990904	ribonucleoprotein complex
0.34	GO:0005929	cilium
0.33	GO:0071944	cell periphery
0.32	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.34	EC:2.7.1.23	GO:0003951
0.34	KEGG:R00104	GO:0003951

tr|R4GLX9|R4GLX9_CHICK
Uncharacterized protein
Search

MDFIC

0.96	MyoD family inhibitor domain containing

0.78	GO:0042308	negative regulation of protein import into nucleus
0.67	GO:0045892	negative regulation of transcription, DNA-templated
0.59	GO:0050434	positive regulation of viral transcription
0.53	GO:0048704	embryonic skeletal system morphogenesis
0.51	GO:0060707	trophoblast giant cell differentiation
0.46	GO:0030111	regulation of Wnt signaling pathway
0.45	GO:0007257	activation of JUN kinase activity
0.41	GO:0045893	positive regulation of transcription, DNA-templated
0.41	GO:0009950	dorsal/ventral axis specification
0.41	GO:0043392	negative regulation of DNA binding

0.58	GO:0008134	transcription factor binding
0.48	GO:0042802	identical protein binding
0.44	GO:0030332	cyclin binding
0.40	GO:0050825	ice binding

0.67	GO:0005730	nucleolus
0.47	GO:0005737	cytoplasm

tr|R4GLY5|R4GLY5_CHICK
Uncharacterized protein
Search

0.61	GO:0007165	signal transduction
0.52	GO:0071356	cellular response to tumor necrosis factor
0.52	GO:0032496	response to lipopolysaccharide
0.52	GO:0006915	apoptotic process
0.51	GO:0006954	inflammatory response
0.50	GO:0006955	immune response
0.49	GO:0042127	regulation of cell proliferation
0.48	GO:0042981	regulation of apoptotic process
0.47	GO:0007275	multicellular organism development
0.40	GO:0035023	regulation of Rho protein signal transduction

0.54	GO:0005031	tumor necrosis factor-activated receptor activity
0.43	GO:0043120	tumor necrosis factor binding
0.41	GO:0005089	Rho guanyl-nucleotide exchange factor activity

0.45	GO:0005887	integral component of plasma membrane
0.37	GO:0044444	cytoplasmic part
0.36	GO:0043227	membrane-bounded organelle
0.36	GO:0030027	lamellipodium
0.35	GO:0005911	cell-cell junction
0.35	GO:0043229	intracellular organelle
0.34	GO:0005576	extracellular region

tr|R4GLY7|R4GLY7_CHICK
Elongation of very long chain fatty acids protein
Search

ELOVL6

0.55	Elongation of very long chain fatty acids protein 6

0.76	GO:0019367	fatty acid elongation, saturated fatty acid
0.75	GO:0042761	very long-chain fatty acid biosynthetic process
0.69	GO:0034625	fatty acid elongation, monounsaturated fatty acid
0.67	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.63	GO:0006636	unsaturated fatty acid biosynthetic process
0.50	GO:0042759	long-chain fatty acid biosynthetic process
0.49	GO:0034626	fatty acid elongation, polyunsaturated fatty acid
0.48	GO:0030148	sphingolipid biosynthetic process
0.35	GO:0045540	regulation of cholesterol biosynthetic process

0.82	GO:0102756	very-long-chain 3-ketoacyl-CoA synthase activity
0.82	GO:0102338	3-oxo-lignoceronyl-CoA synthase activity
0.82	GO:0102336	3-oxo-arachidoyl-CoA synthase activity
0.82	GO:0102337	3-oxo-cerotoyl-CoA synthase activity
0.76	GO:0009922	fatty acid elongase activity
0.33	GO:0005515	protein binding

0.62	GO:0005783	endoplasmic reticulum
0.59	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.56	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.82

EC:2.3.1.199

GO:0102338

tr|R4GLY8|R4GLY8_CHICK
Uncharacterized protein
Search

0.62	Neuropeptide FF receptor 2

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.64	GO:0018298	protein-chromophore linkage
0.50	GO:0009583	detection of light stimulus
0.37	GO:0007601	visual perception
0.35	GO:0095500	acetylcholine receptor signaling pathway
0.32	GO:0050911	detection of chemical stimulus involved in sensory perception of smell

0.72	GO:0004930	G-protein coupled receptor activity
0.68	GO:0009881	photoreceptor activity
0.35	GO:0015464	acetylcholine receptor activity
0.32	GO:0016500	protein-hormone receptor activity
0.32	GO:0016758	transferase activity, transferring hexosyl groups
0.32	GO:0004984	olfactory receptor activity

0.46	GO:0001750	photoreceptor outer segment
0.38	GO:0005578	proteinaceous extracellular matrix
0.33	GO:0005887	integral component of plasma membrane

0.32

GO:0016758

tr|R4GLZ1|R4GLZ1_CHICK
Uncharacterized protein
Search

0.73	Lateral signaling target protein 2 like protein (Fragment)

0.53	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity
0.35	GO:0046854	phosphatidylinositol phosphorylation

0.53	GO:0046872	metal ion binding
0.51	GO:0032266	phosphatidylinositol-3-phosphate binding
0.41	GO:0046983	protein dimerization activity
0.36	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity

0.52	GO:0031901	early endosome membrane
0.45	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.36	EC:2.7.1.150	GO:0000285
0.36	KEGG:R05802	GO:0000285

tr|R4GLZ2|R4GLZ2_CHICK
Claudin
Search

CLDN20

0.70

Claudin

0.35	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.33	GO:0043269	regulation of ion transport

0.62	GO:0005198	structural molecule activity
0.34	GO:0042802	identical protein binding

0.81	GO:0005923	bicellular tight junction
0.55	GO:0005886	plasma membrane
0.31	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|R4GLZ3|R4GLZ3_CHICK
Uncharacterized protein
Search

CSRNP1

0.96	Cysteine and serine rich nuclear protein 1

0.74	GO:0060325	face morphogenesis
0.74	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.72	GO:0060021	palate development
0.70	GO:0048705	skeletal system morphogenesis
0.69	GO:0006366	transcription by RNA polymerase II
0.69	GO:0045944	positive regulation of transcription by RNA polymerase II
0.67	GO:0009791	post-embryonic development
0.58	GO:0030901	midbrain development
0.57	GO:0021536	diencephalon development
0.52	GO:0010923	negative regulation of phosphatase activity

0.74	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.60	GO:0043565	sequence-specific DNA binding
0.35	GO:0005515	protein binding

0.57

GO:0005634

nucleus

tr|R4GLZ9|R4GLZ9_CHICK
Uncharacterized protein
Search

METTL20

0.70	Methyltransferase-like protein 20

0.67	GO:1904733	negative regulation of electron transfer activity
0.67	GO:1904736	negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase
0.63	GO:0032259	methylation
0.54	GO:0018205	peptidyl-lysine modification
0.54	GO:0008213	protein alkylation

0.63	GO:0008168	methyltransferase activity
0.56	GO:0031072	heat shock protein binding
0.46	GO:0140096	catalytic activity, acting on a protein

0.55	GO:0005759	mitochondrial matrix
0.46	GO:0043234	protein complex

0.63

GO:0008168

tr|R4GM05|R4GM05_CHICK
Uncharacterized protein
Search

PRRG3

0.97	Transmembrane gamma-carboxyglutamic acid protein 3

0.49	GO:0007596	blood coagulation
0.42	GO:0006508	proteolysis
0.39	GO:0051897	positive regulation of protein kinase B signaling
0.35	GO:0051604	protein maturation
0.33	GO:0030335	positive regulation of cell migration
0.33	GO:0032101	regulation of response to external stimulus
0.33	GO:0044537	regulation of circulating fibrinogen levels
0.33	GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway
0.33	GO:1901552	positive regulation of endothelial cell development
0.33	GO:1903140	regulation of establishment of endothelial barrier

0.69	GO:0005509	calcium ion binding
0.45	GO:0004252	serine-type endopeptidase activity
0.37	GO:0005543	phospholipid binding
0.32	GO:0005515	protein binding

0.66	GO:0005576	extracellular region
0.33	GO:1905286	serine-type peptidase complex
0.33	GO:0005796	Golgi lumen
0.33	GO:0031233	intrinsic component of external side of plasma membrane
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.45

GO:0004252

tr|R4GM10|R4GM10_CHICK
Fructose-bisphosphate aldolase
Search

ALDOC

0.55	Fructose-bisphosphate aldolase C

0.70	GO:0006096	glycolytic process
0.57	GO:0030388	fructose 1,6-bisphosphate metabolic process
0.52	GO:0030855	epithelial cell differentiation
0.44	GO:0006000	fructose metabolic process
0.44	GO:0046716	muscle cell cellular homeostasis
0.44	GO:0007339	binding of sperm to zona pellucida
0.43	GO:0006941	striated muscle contraction
0.40	GO:0051289	protein homotetramerization
0.40	GO:0006754	ATP biosynthetic process
0.39	GO:0008360	regulation of cell shape

0.78	GO:0004332	fructose-bisphosphate aldolase activity
0.51	GO:0008092	cytoskeletal protein binding
0.46	GO:0070061	fructose binding
0.42	GO:0045296	cadherin binding
0.37	GO:0042802	identical protein binding
0.36	GO:0002020	protease binding
0.35	GO:0061609	fructose-1-phosphate aldolase activity
0.34	GO:0051117	ATPase binding
0.33	GO:0003723	RNA binding
0.33	GO:0004672	protein kinase activity

0.45	GO:0061827	sperm head
0.44	GO:0005739	mitochondrion
0.43	GO:0070062	extracellular exosome
0.40	GO:0015629	actin cytoskeleton
0.40	GO:0005829	cytosol
0.39	GO:0031430	M band
0.39	GO:0035686	sperm fibrous sheath
0.39	GO:0031674	I band
0.37	GO:1904724	tertiary granule lumen
0.37	GO:1904813	ficolin-1-rich granule lumen

0.78

EC:4.1.2.13

GO:0004332

tr|R4GM14|R4GM14_CHICK
Uncharacterized protein
Search

DUSP16

0.97	Dual specificity protein phosphatase 16

0.84	GO:0000188	inactivation of MAPK activity
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.37	GO:0045208	MAPK phosphatase export from nucleus
0.36	GO:0045204	MAPK export from nucleus
0.34	GO:0016310	phosphorylation

0.85	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.37	GO:0005515	protein binding
0.35	GO:0016301	kinase activity

0.51	GO:0005654	nucleoplasm
0.40	GO:0005737	cytoplasm
0.34	GO:0097708	intracellular vesicle

0.85

EC:3.1.3

GO:0017017

tr|R4GM18|R4GM18_CHICK
Uncharacterized protein
Search

KLF9

0.95	Kruppel like factor 9

0.60	GO:0071387	cellular response to cortisol stimulus
0.58	GO:0097067	cellular response to thyroid hormone stimulus
0.57	GO:0010839	negative regulation of keratinocyte proliferation
0.53	GO:0007623	circadian rhythm
0.43	GO:1902070	positive regulation of sphingolipid mediated signaling pathway
0.42	GO:0006357	regulation of transcription by RNA polymerase II
0.41	GO:0045893	positive regulation of transcription, DNA-templated
0.40	GO:0031018	endocrine pancreas development
0.38	GO:0006366	transcription by RNA polymerase II
0.37	GO:0050847	progesterone receptor signaling pathway

0.51	GO:0003676	nucleic acid binding
0.40	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.39	GO:0003682	chromatin binding
0.35	GO:0046872	metal ion binding
0.34	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding

0.48	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.34	GO:0005925	focal adhesion
0.30	GO:0031224	intrinsic component of membrane

tr|R4GM20|R4GM20_CHICK
Uncharacterized protein
Search

IL17C

0.78	Interleukin 17C

0.79	GO:0006954	inflammatory response
0.76	GO:0010469	regulation of receptor activity
0.46	GO:1900017	positive regulation of cytokine production involved in inflammatory response
0.42	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production
0.42	GO:0032755	positive regulation of interleukin-6 production
0.42	GO:0030851	granulocyte differentiation
0.42	GO:0032757	positive regulation of interleukin-8 production
0.41	GO:1903707	negative regulation of hemopoiesis
0.39	GO:0032634	interleukin-5 production
0.39	GO:0032616	interleukin-13 production

0.81	GO:0005125	cytokine activity
0.39	GO:0042803	protein homodimerization activity
0.34	GO:0005126	cytokine receptor binding
0.33	GO:0046872	metal ion binding

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|R4GM22|R4GM22_CHICK
Uncharacterized protein
Search

0.88	Regulator of G-protein signalling 2

0.82	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.72	GO:0043547	positive regulation of GTPase activity
0.68	GO:0009968	negative regulation of signal transduction
0.57	GO:0010519	negative regulation of phospholipase activity
0.57	GO:0060087	relaxation of vascular smooth muscle
0.57	GO:0060452	positive regulation of cardiac muscle contraction
0.57	GO:0055119	relaxation of cardiac muscle
0.56	GO:0010614	negative regulation of cardiac muscle hypertrophy
0.55	GO:0043949	regulation of cAMP-mediated signaling
0.54	GO:0050873	brown fat cell differentiation

0.73	GO:0005096	GTPase activator activity
0.59	GO:0001965	G-protein alpha-subunit binding
0.39	GO:0048487	beta-tubulin binding
0.34	GO:0005516	calmodulin binding
0.33	GO:0046982	protein heterodimerization activity

0.57	GO:0005829	cytosol
0.53	GO:0009898	cytoplasmic side of plasma membrane
0.50	GO:0005634	nucleus
0.42	GO:0019897	extrinsic component of plasma membrane
0.38	GO:0043005	neuron projection
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0044446	intracellular organelle part
0.35	GO:0032809	neuronal cell body membrane
0.35	GO:0043204	perikaryon

tr|R4GM24|R4GM24_CHICK
Uncharacterized protein
Search

GRIN3B

0.91	Glutamate ionotropic receptor NMDA type subunit 3B

0.77	GO:0060079	excitatory postsynaptic potential
0.75	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0034220	ion transmembrane transport
0.54	GO:0006816	calcium ion transport
0.52	GO:0045471	response to ethanol
0.52	GO:0060134	prepulse inhibition
0.50	GO:0051924	regulation of calcium ion transport
0.49	GO:0016358	dendrite development
0.48	GO:0051205	protein insertion into membrane
0.34	GO:0048511	rhythmic process

0.80	GO:0005234	extracellularly glutamate-gated ion channel activity
0.76	GO:0004970	ionotropic glutamate receptor activity
0.56	GO:0005262	calcium channel activity
0.54	GO:0016594	glycine binding
0.51	GO:0099094	ligand-gated cation channel activity
0.49	GO:0022843	voltage-gated cation channel activity
0.47	GO:0042802	identical protein binding
0.37	GO:0051721	protein phosphatase 2A binding
0.33	GO:0005509	calcium ion binding

0.76	GO:0098794	postsynapse
0.63	GO:0017146	NMDA selective glutamate receptor complex
0.58	GO:0043025	neuronal cell body
0.56	GO:0097060	synaptic membrane
0.51	GO:0030054	cell junction
0.49	GO:0043005	neuron projection
0.36	GO:0032279	asymmetric synapse
0.33	GO:0043226	organelle

tr|R4GM29|R4GM29_CHICK
Uncharacterized protein
Search

MYL3

0.90	Myosin light chain 1, cardiac muscle

0.63	GO:0002026	regulation of the force of heart contraction
0.62	GO:0060047	heart contraction
0.61	GO:0006941	striated muscle contraction
0.55	GO:0048738	cardiac muscle tissue development
0.54	GO:0003208	cardiac ventricle morphogenesis
0.54	GO:0060415	muscle tissue morphogenesis
0.54	GO:0006942	regulation of striated muscle contraction
0.49	GO:0032781	positive regulation of ATPase activity
0.40	GO:0055006	cardiac cell development
0.39	GO:0045214	sarcomere organization

0.69	GO:0005509	calcium ion binding
0.61	GO:0003785	actin monomer binding
0.47	GO:0051015	actin filament binding
0.37	GO:0032038	myosin II heavy chain binding
0.37	GO:0003774	motor activity
0.35	GO:0008307	structural constituent of muscle
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0004872	receptor activity

0.62	GO:0031672	A band
0.53	GO:0031674	I band
0.41	GO:0016459	myosin complex
0.34	GO:0005829	cytosol
0.34	GO:0008305	integrin complex

0.33

GO:0004252

tr|R4GM35|R4GM35_CHICK
Uncharacterized protein
Search

C1QTNF6

0.95	Complement C1q tumor necrosis factor-related protein 6

0.49	GO:0070208	protein heterotrimerization
0.49	GO:2000860	positive regulation of aldosterone secretion
0.48	GO:0090331	negative regulation of platelet aggregation
0.46	GO:0051897	positive regulation of protein kinase B signaling
0.45	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.45	GO:0010906	regulation of glucose metabolic process
0.44	GO:0043410	positive regulation of MAPK cascade
0.43	GO:0051260	protein homooligomerization
0.42	GO:0010628	positive regulation of gene expression

0.45	GO:0005518	collagen binding
0.37	GO:0042802	identical protein binding

0.77	GO:0005581	collagen trimer
0.65	GO:0005576	extracellular region
0.41	GO:0005887	integral component of plasma membrane

tr|R4GM36|R4GM36_CHICK
Uncharacterized protein
Search

IKBIP

0.87	IKBKB interacting protein (Fragment)

0.36

GO:0016310

phosphorylation

0.37

GO:0016301

kinase activity

0.70	GO:0005783	endoplasmic reticulum
0.30	GO:0044425	membrane part

tr|R4GM45|R4GM45_CHICK
Uncharacterized protein
Search

tr|R4GM46|R4GM46_CHICK
Uncharacterized protein
Search

TPBG

0.95	Trophoblast glycoprotein like

0.56	GO:0051965	positive regulation of synapse assembly
0.43	GO:2000052	positive regulation of non-canonical Wnt signaling pathway
0.42	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.35	GO:0007155	cell adhesion

0.49	GO:0005783	endoplasmic reticulum
0.36	GO:0009986	cell surface
0.35	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|R4GM47|R4GM47_CHICK
Uncharacterized protein
Search

DMRT2

0.97	DM domain-containing transcription factor DMRT2

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:2000287	positive regulation of myotome development
0.49	GO:0014807	regulation of somitogenesis
0.47	GO:0007275	multicellular organism development
0.44	GO:0006915	apoptotic process
0.44	GO:0051254	positive regulation of RNA metabolic process
0.43	GO:0010557	positive regulation of macromolecule biosynthetic process
0.43	GO:0031328	positive regulation of cellular biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0043565	sequence-specific DNA binding
0.47	GO:0046872	metal ion binding
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0042803	protein homodimerization activity
0.43	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|R4GM48|R4GM48_CHICK
Uncharacterized protein
Search

GTF2A1L

0.96	General transcription factor IIA subunit 1 like

0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.55	GO:0030100	regulation of endocytosis
0.51	GO:0006897	endocytosis
0.45	GO:0006413	translational initiation
0.39	GO:2001141	regulation of RNA biosynthetic process
0.36	GO:0050890	cognition
0.35	GO:0036465	synaptic vesicle recycling
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.33	GO:0042795	snRNA transcription by RNA polymerase II

0.45	GO:0003713	transcription coactivator activity
0.45	GO:0003743	translation initiation factor activity
0.44	GO:0001103	RNA polymerase II repressing transcription factor binding
0.42	GO:0017025	TBP-class protein binding
0.40	GO:0046982	protein heterodimerization activity
0.36	GO:0003677	DNA binding

0.83	GO:0005672	transcription factor TFIIA complex
0.41	GO:0005669	transcription factor TFIID complex
0.39	GO:0005829	cytosol
0.35	GO:0098793	presynapse
0.33	GO:0030131	clathrin adaptor complex

tr|R4GM50|R4GM50_CHICK
Uncharacterized protein
Search

0.65	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.46	GO:0009966	regulation of signal transduction
0.46	GO:2000669	negative regulation of dendritic cell apoptotic process
0.46	GO:0001768	establishment of T cell polarity
0.45	GO:0071731	response to nitric oxide
0.45	GO:0034695	response to prostaglandin E
0.45	GO:0036336	dendritic cell migration
0.45	GO:0090023	positive regulation of neutrophil chemotaxis
0.45	GO:0065009	regulation of molecular function

0.84	GO:0008009	chemokine activity
0.46	GO:0031735	CCR10 chemokine receptor binding

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane
0.30	GO:0005623	cell

tr|R4GM53|R4GM53_CHICK
Uncharacterized protein
Search

tr|R4GM61|R4GM61_CHICK
Uncharacterized protein
Search

PIPOX

0.95	Pipecolic acid and sarcosine oxidase

0.82	GO:0033514	L-lysine catabolic process to acetyl-CoA via L-pipecolate
0.65	GO:0046653	tetrahydrofolate metabolic process
0.53	GO:0055114	oxidation-reduction process

0.80	GO:0050031	L-pipecolate oxidase activity
0.76	GO:0008115	sarcosine oxidase activity
0.64	GO:0005102	receptor binding

0.67

GO:0042579

microbody

0.80	EC:1.5.3.7	GO:0050031
0.80	KEGG:R02204	GO:0050031

tr|R4GM64|R4GM64_CHICK
Uncharacterized protein
Search

FLAD1

0.75	FAD synthase

0.69	GO:0072388	flavin adenine dinucleotide biosynthetic process
0.69	GO:0046443	FAD metabolic process
0.38	GO:0055114	oxidation-reduction process
0.34	GO:0006771	riboflavin metabolic process
0.33	GO:0030488	tRNA methylation

0.69	GO:0003919	FMN adenylyltransferase activity
0.49	GO:0032559	adenyl ribonucleotide binding
0.48	GO:0008144	drug binding
0.48	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0009019	tRNA (guanine-N1-)-methyltransferase activity
0.33	GO:0005515	protein binding
0.33	GO:0003677	DNA binding

0.49	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane
0.35	GO:0005759	mitochondrial matrix
0.33	GO:0005634	nucleus

0.69	EC:2.7.7.2	GO:0003919
0.69	KEGG:R00161	GO:0003919

tr|R4GM67|R4GM67_CHICK
Uncharacterized protein
Search

0.63	macrophage mannose receptor 1

0.65	GO:0071353	cellular response to interleukin-4
0.63	GO:0071346	cellular response to interferon-gamma
0.62	GO:0071222	cellular response to lipopolysaccharide
0.55	GO:0006898	receptor-mediated endocytosis
0.49	GO:0007165	signal transduction

0.64	GO:0005537	mannose binding
0.55	GO:0004888	transmembrane signaling receptor activity

0.59	GO:0010008	endosome membrane
0.57	GO:0009986	cell surface
0.46	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|R4GM71|R4GM71_CHICK
Phosphatidylcholine-sterol acyltransferase
Search

LCAT

0.95	Phosphatidylcholine-sterol acyltransferase

0.67	GO:0034435	cholesterol esterification
0.66	GO:0034372	very-low-density lipoprotein particle remodeling
0.65	GO:0034375	high-density lipoprotein particle remodeling
0.64	GO:0043691	reverse cholesterol transport
0.64	GO:0090107	regulation of high-density lipoprotein particle assembly
0.62	GO:0008203	cholesterol metabolic process
0.62	GO:0042632	cholesterol homeostasis
0.61	GO:0006656	phosphatidylcholine biosynthetic process
0.54	GO:0042158	lipoprotein biosynthetic process
0.36	GO:0051384	response to glucocorticoid

0.72	GO:0008374	O-acyltransferase activity
0.67	GO:0034186	apolipoprotein A-I binding
0.36	GO:0004623	phospholipase A2 activity

0.63	GO:0034364	high-density lipoprotein particle
0.38	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.72

EC:2.3.1

GO:0008374

tr|R4GM73|R4GM73_CHICK
Uncharacterized protein
Search

MRPS33

0.93	Mitochondrial ribosomal protein S33

0.36	GO:0070126	mitochondrial translational termination
0.35	GO:0070125	mitochondrial translational elongation

0.35

GO:0003735

structural constituent of ribosome

0.55	GO:0005840	ribosome
0.47	GO:0005739	mitochondrion
0.36	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0031090	organelle membrane
0.34	GO:0031975	envelope

tr|R4GM78|R4GM78_CHICK
Uncharacterized protein
Search

0.11	Pancreatic triacylglycerol lipase (Fragment)

0.45	GO:0006629	lipid metabolic process
0.39	GO:1901575	organic substance catabolic process

0.70	GO:0052689	carboxylic ester hydrolase activity
0.50	GO:0016298	lipase activity
0.37	GO:0046872	metal ion binding

0.66

GO:0005576

extracellular region

0.70	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.70	KEGG:R00630	GO:0052689

tr|R4GM79|R4GM79_CHICK
Uncharacterized protein
Search

TOP1

0.45	DNA topoisomerase I

0.71	GO:0006265	DNA topological change
0.58	GO:0040016	embryonic cleavage
0.57	GO:0032922	circadian regulation of gene expression
0.54	GO:0006338	chromatin remodeling
0.54	GO:0018105	peptidyl-serine phosphorylation
0.49	GO:0042493	response to drug
0.48	GO:0006260	DNA replication
0.43	GO:0007059	chromosome segregation
0.36	GO:0012501	programmed cell death
0.36	GO:0071373	cellular response to luteinizing hormone stimulus

0.75	GO:0003917	DNA topoisomerase type I activity
0.58	GO:0097100	supercoiled DNA binding
0.56	GO:0001046	core promoter sequence-specific DNA binding
0.53	GO:0003682	chromatin binding
0.52	GO:0019904	protein domain specific binding
0.50	GO:0003697	single-stranded DNA binding
0.49	GO:0004674	protein serine/threonine kinase activity
0.42	GO:0030554	adenyl nucleotide binding
0.41	GO:0097367	carbohydrate derivative binding
0.41	GO:0008144	drug binding

0.67	GO:0005694	chromosome
0.57	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)
0.56	GO:0043204	perikaryon
0.55	GO:0001650	fibrillar center
0.54	GO:0000932	P-body
0.50	GO:0032993	protein-DNA complex
0.49	GO:0005654	nucleoplasm
0.36	GO:0001651	dense fibrillar component
0.35	GO:0019013	viral nucleocapsid
0.34	GO:0044815	DNA packaging complex

0.75

EC:5.99.1.2

GO:0003917

tr|R4GM80|R4GM80_CHICK
Uncharacterized protein
Search

0.75	GO:0009190	cyclic nucleotide biosynthetic process
0.63	GO:0035556	intracellular signal transduction

0.74	GO:0016849	phosphorus-oxygen lyase activity
0.53	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding

0.45	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

0.74

EC:4.6

GO:0016849

tr|R4GM81|R4GM81_CHICK
Uncharacterized protein
Search

0.93	Transmembrane protease serine 11E

0.59	GO:0006508	proteolysis
0.47	GO:0050890	cognition
0.37	GO:0006898	receptor-mediated endocytosis
0.35	GO:0046598	positive regulation of viral entry into host cell
0.33	GO:0051604	protein maturation

0.66	GO:0004252	serine-type endopeptidase activity
0.39	GO:0005044	scavenger receptor activity
0.33	GO:0016758	transferase activity, transferring hexosyl groups
0.33	GO:0005515	protein binding

0.58	GO:0005887	integral component of plasma membrane
0.58	GO:0005576	extracellular region
0.46	GO:0043204	perikaryon
0.45	GO:0030425	dendrite

0.66

GO:0004252

tr|R4GM85|R4GM85_CHICK
Uncharacterized protein
Search

0.73	Heat shock protein beta-7

tr|R4GM86|R4GM86_CHICK
Uncharacterized protein
Search

CCBE1

0.97	Collagen and calcium-binding EGF domain-containing protein 1

0.62	GO:0001946	lymphangiogenesis
0.59	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway
0.59	GO:1901492	positive regulation of lymphangiogenesis
0.58	GO:0010575	positive regulation of vascular endothelial growth factor production
0.58	GO:0010954	positive regulation of protein processing
0.57	GO:0003016	respiratory system process
0.55	GO:0010595	positive regulation of endothelial cell migration
0.54	GO:0045766	positive regulation of angiogenesis
0.54	GO:0030324	lung development
0.48	GO:0048845	venous blood vessel morphogenesis

0.67	GO:0005509	calcium ion binding
0.56	GO:0002020	protease binding
0.55	GO:0005518	collagen binding
0.37	GO:0005201	extracellular matrix structural constituent

0.67	GO:0005581	collagen trimer
0.52	GO:0005578	proteinaceous extracellular matrix
0.50	GO:0005615	extracellular space
0.35	GO:0044420	extracellular matrix component
0.33	GO:0099080	supramolecular complex
0.32	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016020	membrane

tr|R4GM98|R4GM98_CHICK
Nucleoside diphosphate kinase
Search

NME3

0.45	Nucleoside diphosphate kinase A

0.79	GO:0006228	UTP biosynthetic process
0.79	GO:0006183	GTP biosynthetic process
0.75	GO:0046036	CTP metabolic process
0.70	GO:0006165	nucleoside diphosphate phosphorylation
0.43	GO:0042981	regulation of apoptotic process
0.40	GO:0006171	cAMP biosynthetic process
0.37	GO:2000026	regulation of multicellular organismal development
0.35	GO:0022603	regulation of anatomical structure morphogenesis
0.35	GO:0015949	nucleobase-containing small molecule interconversion
0.35	GO:0051094	positive regulation of developmental process

0.79	GO:0004550	nucleoside diphosphate kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding
0.33	GO:0004519	endonuclease activity

0.42	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.34	GO:0001726	ruffle
0.34	GO:0030027	lamellipodium
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane

0.79

EC:2.7.4.6

GO:0004550

tr|R4GMA0|R4GMA0_CHICK
Uncharacterized protein
Search

0.10	Proline rich 14 like

0.54	GO:0016540	protein autoprocessing
0.51	GO:0006646	phosphatidylethanolamine biosynthetic process

0.54	GO:0004609	phosphatidylserine decarboxylase activity
0.46	GO:0070001	aspartic-type peptidase activity
0.44	GO:0004175	endopeptidase activity

0.52

GO:0031305

integral component of mitochondrial inner membrane

0.54	EC:4.1.1.65	GO:0004609
0.54	KEGG:R02055	GO:0004609

tr|R4GMA6|R4GMA6_CHICK
Uncharacterized protein
Search

RHOG

0.92	Ras homolog gene family, member Gb

0.77	GO:0007264	small GTPase mediated signal transduction
0.68	GO:1903078	positive regulation of protein localization to plasma membrane
0.68	GO:1900027	regulation of ruffle assembly
0.67	GO:0090630	activation of GTPase activity
0.65	GO:0060326	cell chemotaxis
0.59	GO:0030036	actin cytoskeleton organization
0.59	GO:0045893	positive regulation of transcription, DNA-templated
0.47	GO:0009617	response to bacterium
0.34	GO:0016192	vesicle-mediated transport

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005622	intracellular
0.41	GO:0005925	focal adhesion
0.41	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

tr|R4GMA8|R4GMA8_CHICK
Uncharacterized protein
Search

NANOS1

0.88	Transcription factor Nanos1

0.72	GO:0006417	regulation of translation
0.51	GO:0098749	cerebellar neuron development
0.49	GO:0016477	cell migration
0.48	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.47	GO:0090132	epithelium migration
0.47	GO:0040008	regulation of growth
0.46	GO:0001894	tissue homeostasis
0.46	GO:0034249	negative regulation of cellular amide metabolic process
0.45	GO:0007281	germ cell development
0.44	GO:0032269	negative regulation of cellular protein metabolic process

0.63	GO:0008270	zinc ion binding
0.59	GO:0003723	RNA binding
0.40	GO:0030371	translation repressor activity
0.33	GO:0005515	protein binding

0.50	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0060293	germ plasm
0.40	GO:0098975	postsynapse of neuromuscular junction

tr|R4GMB2|R4GMB2_CHICK
Uncharacterized protein
Search

0.39

GO:0003676

nucleic acid binding

0.65

GO:0005829

cytosol

tr|R4GMB3|R4GMB3_CHICK
Uncharacterized protein
Search

tr|R4GMB5|R4GMB5_CHICK
Fibroblast growth factor
Search

FGF19

0.62	Fibroblast growth factor

0.84	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.66	GO:1904252	negative regulation of bile acid metabolic process
0.65	GO:0070857	regulation of bile acid biosynthetic process
0.63	GO:0010894	negative regulation of steroid biosynthetic process
0.63	GO:0046326	positive regulation of glucose import
0.61	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.61	GO:0046330	positive regulation of JNK cascade
0.60	GO:0008284	positive regulation of cell proliferation
0.53	GO:0031327	negative regulation of cellular biosynthetic process

0.85	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.37	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity

0.66	GO:0005576	extracellular region
0.34	GO:0032580	Golgi cisterna membrane
0.30	GO:0016021	integral component of membrane

0.37	EC:2.7.1.153	GO:0046934
0.37	KEGG:R04545	GO:0046934

tr|R4GMC6|R4GMC6_CHICK
Neurotrophin-3
Search

NTF3

0.64	Neurotrophin-3

0.75	GO:0010469	regulation of receptor activity
0.55	GO:0050930	induction of positive chemotaxis
0.54	GO:2000251	positive regulation of actin cytoskeleton reorganization
0.54	GO:0032148	activation of protein kinase B activity
0.54	GO:0002092	positive regulation of receptor internalization
0.53	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation
0.53	GO:0050918	positive chemotaxis
0.53	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.52	GO:0090630	activation of GTPase activity
0.52	GO:0000187	activation of MAPK activity

0.85	GO:0005165	neurotrophin receptor binding
0.78	GO:0008083	growth factor activity
0.54	GO:0042056	chemoattractant activity
0.35	GO:0048406	nerve growth factor binding

0.40	GO:0031410	cytoplasmic vesicle
0.38	GO:0005576	extracellular region
0.34	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016020	membrane

tr|R4GMD2|R4GMD2_CHICK
Uncharacterized protein
Search

TERB2

0.97	Telomere repeats-binding bouquet formation protein 2

0.86	GO:0070197	meiotic attachment of telomere to nuclear envelope
0.85	GO:0007129	synapsis

0.83	GO:0005637	nuclear inner membrane
0.82	GO:0000784	nuclear chromosome, telomeric region

tr|R4GMD4|R4GMD4_CHICK
Uncharacterized protein
Search

0.91	WD repeat-containing protein 25

0.53

GO:0005515

protein binding

tr|R4GMD9|R4GMD9_CHICK
Uncharacterized protein
Search

TXNDC17

0.95	Thioredoxin domain-containing protein 17

0.77	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.63	GO:0098869	cellular oxidant detoxification
0.52	GO:0055114	oxidation-reduction process
0.38	GO:0006508	proteolysis
0.36	GO:0045454	cell redox homeostasis

0.79	GO:0047134	protein-disulfide reductase activity
0.66	GO:0004601	peroxidase activity
0.38	GO:0008233	peptidase activity
0.37	GO:0030158	protein xylosyltransferase activity
0.36	GO:0005515	protein binding
0.35	GO:0008270	zinc ion binding
0.33	GO:0003677	DNA binding

0.67	GO:0005829	cytosol
0.42	GO:0070062	extracellular exosome

0.79	EC:1.8.1.8	GO:0047134
0.66	KEGG:R03532	GO:0004601

tr|R4GME1|R4GME1_CHICK
Uncharacterized protein
Search

PFDN2

0.90	Prefoldin subunit 2

0.69	GO:0006457	protein folding
0.51	GO:0051495	positive regulation of cytoskeleton organization
0.37	GO:0007021	tubulin complex assembly
0.34	GO:0007155	cell adhesion
0.33	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.33	GO:0044409	entry into host
0.33	GO:0006661	phosphatidylinositol biosynthetic process
0.33	GO:0019058	viral life cycle
0.33	GO:0046034	ATP metabolic process

0.71	GO:0051082	unfolded protein binding
0.58	GO:0044183	protein binding involved in protein folding
0.36	GO:0015631	tubulin binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0016272	prefoldin complex
0.48	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.44	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.34	GO:0070772	PAS complex
0.30	GO:0031224	intrinsic component of membrane

tr|R4GME5|R4GME5_CHICK
Uncharacterized protein
Search

HELZ

0.85	Helicase with zinc finger

0.31	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.31	GO:2001141	regulation of RNA biosynthetic process
0.31	GO:0010468	regulation of gene expression

0.58	GO:0004386	helicase activity
0.52	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003723	RNA binding
0.33	GO:0003677	DNA binding
0.31	GO:0003700	DNA binding transcription factor activity

0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|R4GME9|R4GME9_CHICK
Uncharacterized protein
Search

0.61	Collagen, type XVI, alpha 1

0.55	GO:0033622	integrin activation
0.54	GO:0051894	positive regulation of focal adhesion assembly
0.53	GO:0033627	cell adhesion mediated by integrin
0.52	GO:0071230	cellular response to amino acid stimulus
0.40	GO:0035124	embryonic caudal fin morphogenesis
0.39	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.39	GO:0031101	fin regeneration
0.39	GO:0007528	neuromuscular junction development
0.38	GO:0048731	system development
0.38	GO:0030198	extracellular matrix organization

0.57	GO:0005201	extracellular matrix structural constituent
0.52	GO:0005178	integrin binding
0.37	GO:0004930	G-protein coupled receptor activity
0.36	GO:0005164	tumor necrosis factor receptor binding
0.35	GO:0042302	structural constituent of cuticle
0.34	GO:0005509	calcium ion binding

0.65	GO:0005581	collagen trimer
0.55	GO:0031012	extracellular matrix
0.39	GO:0031594	neuromuscular junction
0.38	GO:0005788	endoplasmic reticulum lumen
0.37	GO:0099081	supramolecular polymer
0.35	GO:0005811	lipid droplet
0.33	GO:0042613	MHC class II protein complex
0.33	GO:0045177	apical part of cell
0.33	GO:0005789	endoplasmic reticulum membrane
0.32	GO:0005887	integral component of plasma membrane

tr|R4GMF0|R4GMF0_CHICK
Uncharacterized protein
Search

ENC1

0.77	Ectodermal-neural cortex

0.69	GO:0048731	system development
0.67	GO:0010499	proteasomal ubiquitin-independent protein catabolic process
0.62	GO:0016567	protein ubiquitination
0.62	GO:0006417	regulation of translation
0.61	GO:0034249	negative regulation of cellular amide metabolic process
0.58	GO:0032269	negative regulation of cellular protein metabolic process
0.57	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.55	GO:0010629	negative regulation of gene expression
0.53	GO:0007368	determination of left/right symmetry
0.43	GO:0031346	positive regulation of cell projection organization

0.67

GO:0003779

actin binding

0.70	GO:0031463	Cul3-RING ubiquitin ligase complex
0.44	GO:0016363	nuclear matrix
0.43	GO:0043025	neuronal cell body
0.43	GO:0005737	cytoplasm
0.42	GO:0000790	nuclear chromatin
0.41	GO:0005730	nucleolus
0.40	GO:0005654	nucleoplasm
0.37	GO:0005856	cytoskeleton

tr|R4GMF7|R4GMF7_CHICK
Uncharacterized protein
Search

IMMP2L

0.66	Inner mitochondrial membrane peptidase subunit 2

0.80	GO:0006627	protein processing involved in protein targeting to mitochondrion
0.77	GO:0006465	signal peptide processing
0.48	GO:0033108	mitochondrial respiratory chain complex assembly
0.47	GO:0061300	cerebellum vasculature development
0.46	GO:0030728	ovulation
0.45	GO:0001541	ovarian follicle development
0.43	GO:0008015	blood circulation
0.43	GO:0007283	spermatogenesis
0.43	GO:0007420	brain development
0.42	GO:0006801	superoxide metabolic process

0.67	GO:0017171	serine hydrolase activity
0.62	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.40	GO:0003743	translation initiation factor activity
0.33	GO:0003725	double-stranded RNA binding
0.32	GO:0005515	protein binding
0.32	GO:0050660	flavin adenine dinucleotide binding
0.32	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.32	GO:0046872	metal ion binding

0.83	GO:0042720	mitochondrial inner membrane peptidase complex
0.30	GO:0016021	integral component of membrane

0.32

EC:1.1

GO:0016614

tr|R4GMG7|R4GMG7_CHICK
Uncharacterized protein
Search

C12ORF66

0.95	KICSTOR complex protein C12orf66 homolog

0.82	GO:0061462	protein localization to lysosome
0.82	GO:1904262	negative regulation of TORC1 signaling
0.80	GO:0034198	cellular response to amino acid starvation
0.79	GO:0042149	cellular response to glucose starvation
0.41	GO:0043043	peptide biosynthetic process
0.40	GO:0044267	cellular protein metabolic process
0.39	GO:0010467	gene expression
0.38	GO:0009059	macromolecule biosynthetic process
0.38	GO:0016569	covalent chromatin modification
0.37	GO:1903506	regulation of nucleic acid-templated transcription

0.42	GO:0003735	structural constituent of ribosome
0.39	GO:0018024	histone-lysine N-methyltransferase activity
0.38	GO:0008270	zinc ion binding
0.38	GO:0003700	DNA binding transcription factor activity

0.85	GO:0140007	KICSTOR complex
0.71	GO:0005765	lysosomal membrane
0.41	GO:0005840	ribosome
0.40	GO:0005634	nucleus

0.39

EC:2.1.1.43

GO:0018024

tr|R4GMH3|R4GMH3_CHICK
Uncharacterized protein
Search

tr|R4GMH5|R4GMH5_CHICK
Plasminogen
Search

0.10	Plasminogen

0.73	GO:0042730	fibrinolysis
0.70	GO:0048771	tissue remodeling
0.67	GO:0007596	blood coagulation
0.61	GO:0006508	proteolysis
0.48	GO:0060707	trophoblast giant cell differentiation
0.48	GO:0060716	labyrinthine layer blood vessel development
0.48	GO:0071674	mononuclear cell migration
0.47	GO:0045445	myoblast differentiation
0.47	GO:0046716	muscle cell cellular homeostasis
0.47	GO:0042246	tissue regeneration

0.69	GO:0004252	serine-type endopeptidase activity
0.44	GO:0019900	kinase binding
0.37	GO:1904854	proteasome core complex binding
0.37	GO:0019904	protein domain specific binding
0.37	GO:1990405	protein antigen binding
0.36	GO:0034185	apolipoprotein binding
0.36	GO:0005102	receptor binding
0.35	GO:0051087	chaperone binding

0.56	GO:0005576	extracellular region
0.44	GO:0019897	extrinsic component of plasma membrane
0.36	GO:0009897	external side of plasma membrane
0.34	GO:0044218	other organism cell membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004252

tr|R4GMH7|R4GMH7_CHICK
Uncharacterized protein
Search

TRAPPC3L

0.78	Trafficking protein particle complex subunit

0.74	GO:0048193	Golgi vesicle transport
0.43	GO:0046907	intracellular transport
0.33	GO:0065009	regulation of molecular function
0.33	GO:0016236	macroautophagy
0.32	GO:0034613	cellular protein localization
0.32	GO:0015031	protein transport

0.35

GO:0017112

Rab guanyl-nucleotide exchange factor activity

0.80	GO:0030008	TRAPP complex
0.63	GO:0005794	Golgi apparatus
0.63	GO:0005783	endoplasmic reticulum
0.43	GO:0098588	bounding membrane of organelle
0.43	GO:0005829	cytosol
0.42	GO:0031984	organelle subcompartment
0.34	GO:0005801	cis-Golgi network
0.33	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.33	GO:0044440	endosomal part
0.32	GO:0005634	nucleus

tr|R4GMH9|R4GMH9_CHICK
Uncharacterized protein
Search

KBTBD3

0.97	Kelch repeat and BTB domain-containing protein 3

0.73

GO:0016567

protein ubiquitination

0.74

GO:0004842

ubiquitin-protein transferase activity

0.83

GO:0031463

Cul3-RING ubiquitin ligase complex

0.74

GO:0004842

tr|R4GMI0|R4GMI0_CHICK
Uncharacterized protein
Search

AQP10

0.54	LOW QUALITY PROTEIN: aquaporin-10

0.66	GO:0006833	water transport
0.55	GO:0055085	transmembrane transport
0.48	GO:0015791	polyol transport
0.46	GO:0015840	urea transport
0.45	GO:0009636	response to toxic substance
0.42	GO:0015700	arsenite transport
0.41	GO:0008643	carbohydrate transport
0.41	GO:0006863	purine nucleobase transport
0.41	GO:0071320	cellular response to cAMP
0.41	GO:0015837	amine transport

0.69	GO:0022803	passive transmembrane transporter activity
0.49	GO:0005372	water transmembrane transporter activity
0.48	GO:0015168	glycerol transmembrane transporter activity
0.46	GO:0015204	urea transmembrane transporter activity
0.42	GO:0015105	arsenite transmembrane transporter activity
0.41	GO:0005345	purine nucleobase transmembrane transporter activity
0.39	GO:0005350	pyrimidine nucleobase transmembrane transporter activity
0.37	GO:0004012	phospholipid-translocating ATPase activity
0.35	GO:0000287	magnesium ion binding
0.34	GO:0032559	adenyl ribonucleotide binding

0.35	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0012505	endomembrane system
0.32	GO:0005886	plasma membrane
0.32	GO:0031967	organelle envelope
0.32	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.37

EC:3.6.3.1

GO:0004012

tr|R4GMI4|R4GMI4_CHICK
Cyclin-dependent kinases regulatory subunit
Search

0.38	Cyclin-dependent kinases regulatory subunit

0.76	GO:0045859	regulation of protein kinase activity
0.67	GO:0051301	cell division
0.67	GO:0007049	cell cycle
0.52	GO:0008283	cell proliferation
0.50	GO:0045787	positive regulation of cell cycle
0.49	GO:0033674	positive regulation of kinase activity
0.49	GO:0001934	positive regulation of protein phosphorylation
0.49	GO:0007346	regulation of mitotic cell cycle
0.48	GO:0016310	phosphorylation
0.47	GO:0045893	positive regulation of transcription, DNA-templated

0.82	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.52	GO:0043539	protein serine/threonine kinase activator activity
0.51	GO:0043130	ubiquitin binding
0.50	GO:0042393	histone binding
0.50	GO:0016301	kinase activity
0.50	GO:0019901	protein kinase binding
0.44	GO:0003682	chromatin binding
0.32	GO:0003676	nucleic acid binding

0.52	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.51	GO:0019005	SCF ubiquitin ligase complex
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.82

GO:0016538

tr|R4GMI5|R4GMI5_CHICK
Uncharacterized protein
Search

SIX2

0.96	SIX homeobox 2

0.74	GO:0072074	kidney mesenchyme development
0.73	GO:0042474	middle ear morphogenesis
0.73	GO:0090189	regulation of branching involved in ureteric bud morphogenesis
0.71	GO:0008283	cell proliferation
0.71	GO:0072088	nephron epithelium morphogenesis
0.71	GO:0001656	metanephros development
0.70	GO:0048701	embryonic cranial skeleton morphogenesis
0.69	GO:0001708	cell fate specification
0.66	GO:0034504	protein localization to nucleus
0.66	GO:0035239	tube morphogenesis

0.68	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.67	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0032403	protein complex binding
0.54	GO:0008134	transcription factor binding
0.52	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.48	GO:0043233	organelle lumen
0.44	GO:0043232	intracellular non-membrane-bounded organelle
0.43	GO:0044446	intracellular organelle part

tr|R4GMI7|R4GMI7_CHICK
Uncharacterized protein
Search

CARD19

0.97	Bcl10-interacting CARD protein isoform C

0.74

GO:0042981

regulation of apoptotic process

0.34	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

tr|R4GMI9|R4GMI9_CHICK
Myogenic factor
Search

MYF5

0.93	Myogenic factor

0.81	GO:0007517	muscle organ development
0.61	GO:0014706	striated muscle tissue development
0.59	GO:0001502	cartilage condensation
0.58	GO:0043010	camera-type eye development
0.57	GO:0001756	somitogenesis
0.57	GO:0001952	regulation of cell-matrix adhesion
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0006366	transcription by RNA polymerase II
0.56	GO:0048704	embryonic skeletal system morphogenesis

0.68	GO:0046983	protein dimerization activity
0.59	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.54	GO:0003677	DNA binding
0.49	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.49	GO:0001067	regulatory region nucleic acid binding
0.45	GO:0035257	nuclear hormone receptor binding
0.43	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0003713	transcription coactivator activity
0.42	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.52	GO:0070013	intracellular organelle lumen
0.47	GO:0044446	intracellular organelle part
0.43	GO:0030016	myofibril
0.43	GO:0005667	transcription factor complex
0.41	GO:0005829	cytosol
0.40	GO:0005694	chromosome

tr|R4GMJ2|R4GMJ2_CHICK
Uncharacterized protein
Search

ST8SIA3

0.97	W-linked ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3

0.83	GO:0097503	sialylation
0.74	GO:0006486	protein glycosylation
0.61	GO:0001574	ganglioside biosynthetic process
0.56	GO:0006491	N-glycan processing
0.51	GO:0009311	oligosaccharide metabolic process
0.46	GO:0046716	muscle cell cellular homeostasis
0.44	GO:0007517	muscle organ development
0.37	GO:0016051	carbohydrate biosynthetic process

0.84	GO:0008373	sialyltransferase activity
0.50	GO:0042802	identical protein binding
0.35	GO:0033691	sialic acid binding

0.69	GO:0005794	Golgi apparatus
0.37	GO:0098588	bounding membrane of organelle
0.36	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:2.4.99

GO:0008373

tr|R4GMJ3|R4GMJ3_CHICK
Uncharacterized protein
Search

LRRC74B

0.93	leucine-rich repeat-containing protein 74B

tr|R4GMK0|R4GMK0_CHICK
Uncharacterized protein
Search

0.72	Toll like receptor 1 type2

0.84	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
0.82	GO:0050707	regulation of cytokine secretion
0.79	GO:0042494	detection of bacterial lipoprotein
0.79	GO:0070339	response to bacterial lipopeptide
0.78	GO:0045087	innate immune response
0.73	GO:0045410	positive regulation of interleukin-6 biosynthetic process
0.73	GO:0034150	toll-like receptor 6 signaling pathway
0.73	GO:0006954	inflammatory response
0.71	GO:0042088	T-helper 1 type immune response
0.64	GO:0034166	toll-like receptor 10 signaling pathway

0.70	GO:0004888	transmembrane signaling receptor activity
0.45	GO:0035663	Toll-like receptor 2 binding
0.40	GO:0046982	protein heterodimerization activity
0.40	GO:0071723	lipopeptide binding
0.39	GO:0042802	identical protein binding

0.42	GO:0045121	membrane raft
0.41	GO:0043235	receptor complex
0.40	GO:0005794	Golgi apparatus
0.38	GO:0005887	integral component of plasma membrane
0.34	GO:0030670	phagocytic vesicle membrane

tr|R4GMK6|R4GMK6_CHICK
Uncharacterized protein
Search

NOL9

0.84	Polynucleotide 5'-hydroxyl-kinase NOL9

0.57	GO:0016310	phosphorylation
0.43	GO:0000448	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

0.60	GO:0016301	kinase activity
0.41	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.36	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.40	GO:0045111	intermediate filament cytoskeleton
0.39	GO:0005730	nucleolus
0.35	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.38

GO:0016773

tr|R4GRV9|R4GRV9_CHICK
Homeobox protein Hox-A13
Search

0.82	LOW QUALITY PROTEIN: homeobox protein Hox-A13

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.42	GO:1902679	negative regulation of RNA biosynthetic process
0.38	GO:0007275	multicellular organism development
0.36	GO:2001055	positive regulation of mesenchymal cell apoptotic process
0.36	GO:0060847	endothelial cell fate specification
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:0001886	endothelial cell morphogenesis
0.35	GO:0033574	response to testosterone

0.61	GO:0043565	sequence-specific DNA binding
0.43	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.35	GO:0035326	enhancer binding
0.35	GO:0001012	RNA polymerase II regulatory region DNA binding
0.34	GO:0003690	double-stranded DNA binding
0.32	GO:0005515	protein binding

0.59

GO:0005634

nucleus

tr|R9PXL7|R9PXL7_CHICK
Uncharacterized protein
Search

PTDSS2

0.96	Phosphatidylserine synthase 2

0.85

GO:0006659

phosphatidylserine biosynthetic process

0.52

GO:0003882

CDP-diacylglycerol-serine O-phosphatidyltransferase activity

0.48	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.52

EC:2.7.8.8

GO:0003882

tr|R9PXM5|R9PXM5_CHICK
Uncharacterized protein
Search

IGL

0.79	Immmunoglobulin lambda light chain variable region (Fragment)

0.85

GO:0006958

complement activation, classical pathway

0.85

GO:0003823

antigen binding

0.66

GO:0005576

extracellular region

tr|R9PXP2|R9PXP2_CHICK
Cytosolic carboxypeptidase 1
Search

AGTPBP1

0.93	ATP/GTP binding protein 1

0.86	GO:0021702	cerebellar Purkinje cell differentiation
0.68	GO:0035609	C-terminal protein deglutamylation
0.67	GO:0035610	protein side chain deglutamylation
0.64	GO:0021772	olfactory bulb development
0.64	GO:0007628	adult walking behavior
0.62	GO:0050905	neuromuscular process
0.62	GO:0001754	eye photoreceptor cell differentiation
0.61	GO:0060041	retina development in camera-type eye
0.61	GO:0006508	proteolysis
0.57	GO:0007005	mitochondrion organization

0.78	GO:0004181	metallocarboxypeptidase activity
0.63	GO:0008270	zinc ion binding
0.56	GO:0015631	tubulin binding

0.56	GO:0005730	nucleolus
0.53	GO:0005829	cytosol
0.48	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.78

EC:3.4.17

GO:0004181

tr|R9PXP6|R9PXP6_CHICK
Wee1-like protein kinase
Search

WEE2

0.89	Wee1-like protein kinase 2-A

0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.73	GO:0000278	mitotic cell cycle
0.55	GO:1900194	negative regulation of oocyte maturation
0.55	GO:0035038	female pronucleus assembly
0.53	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity
0.53	GO:0007143	female meiotic nuclear division
0.53	GO:0060631	regulation of meiosis I
0.41	GO:0030010	establishment of cell polarity
0.41	GO:0048812	neuron projection morphogenesis
0.40	GO:0000226	microtubule cytoskeleton organization

0.79	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.63	GO:0000287	magnesium ion binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0004674	protein serine/threonine kinase activity
0.35	GO:0003697	single-stranded DNA binding
0.33	GO:0042802	identical protein binding

0.60	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.46	GO:0005829	cytosol
0.42	GO:0044446	intracellular organelle part
0.36	GO:0043232	intracellular non-membrane-bounded organelle

0.79

GO:0004715

tr|R9PXP9|R9PXP9_CHICK
Uncharacterized protein
Search

SPATA18

0.87	Spermatogenesis-associated protein 18

0.66	GO:0035695	mitophagy by induced vacuole formation
0.64	GO:0035694	mitochondrial protein catabolic process
0.64	GO:0033554	cellular response to stress

0.78

GO:0005741

mitochondrial outer membrane

tr|R9PXQ8|R9PXQ8_CHICK
Ubiquitin carboxyl-terminal hydrolase 37
Search

USP37

0.96	Ubiquitin carboxyl-terminal hydrolase 37

0.75	GO:0016579	protein deubiquitination
0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.56	GO:0000082	G1/S transition of mitotic cell cycle
0.51	GO:0006275	regulation of DNA replication
0.39	GO:0051301	cell division
0.34	GO:0021551	central nervous system morphogenesis
0.33	GO:1904888	cranial skeletal system development

0.75	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.51	GO:0019901	protein kinase binding
0.51	GO:0004197	cysteine-type endopeptidase activity

0.44	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

0.75

EC:3.4.19.12

GO:0036459

tr|S4SCC1|S4SCC1_CHICK
Phosphodiesterase
Search

PDE5A

0.58	Phosphodiesterase

0.60	GO:0046069	cGMP catabolic process
0.60	GO:0007165	signal transduction
0.57	GO:0055118	negative regulation of cardiac muscle contraction
0.56	GO:0055119	relaxation of cardiac muscle
0.56	GO:0060282	positive regulation of oocyte development
0.55	GO:0014742	positive regulation of muscle hypertrophy
0.55	GO:0010611	regulation of cardiac muscle hypertrophy
0.54	GO:0030823	regulation of cGMP metabolic process
0.54	GO:0042130	negative regulation of T cell proliferation
0.52	GO:0043406	positive regulation of MAP kinase activity

0.78	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.54	GO:0030553	cGMP binding
0.53	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.36

GO:0005829

cytosol

0.78

EC:3.1.4.17

GO:0004114

tr|S5TQ07|S5TQ07_CHICK
Zinc finger protein 36 C3H1 type-like 1 protein
Search

ZFP36L1

0.97	ZFP36 ring finger protein like 1

0.75	GO:1904582	positive regulation of intracellular mRNA localization
0.74	GO:0097403	cellular response to raffinose
0.74	GO:0061158	3'-UTR-mediated mRNA destabilization
0.74	GO:1902172	regulation of keratinocyte apoptotic process
0.73	GO:0045657	positive regulation of monocyte differentiation
0.73	GO:0045647	negative regulation of erythrocyte differentiation
0.73	GO:1904628	cellular response to phorbol 13-acetate 12-myristate
0.72	GO:0003343	septum transversum development
0.71	GO:0070371	ERK1 and ERK2 cascade
0.71	GO:0038066	p38MAPK cascade

0.73	GO:0035925	mRNA 3'-UTR AU-rich region binding
0.72	GO:0071889	14-3-3 protein binding
0.54	GO:0046872	metal ion binding

0.66	GO:0000932	P-body
0.52	GO:0005634	nucleus
0.45	GO:0005829	cytosol

tr|S6BNL5|S6BNL5_CHICK
Peptidylarginine deiminase type II
Search

PADI2

0.94	Peptidylarginine deiminase

0.80	GO:0018101	protein citrullination
0.59	GO:0010848	regulation of chromatin disassembly
0.59	GO:1901624	negative regulation of lymphocyte chemotaxis
0.58	GO:0070100	negative regulation of chemokine-mediated signaling pathway
0.57	GO:0048096	chromatin-mediated maintenance of transcription
0.56	GO:0030520	intracellular estrogen receptor signaling pathway
0.54	GO:1990823	response to leukemia inhibitory factor
0.52	GO:0016570	histone modification
0.51	GO:0071345	cellular response to cytokine stimulus
0.38	GO:0021762	substantia nigra development

0.79	GO:0004668	protein-arginine deiminase activity
0.68	GO:0005509	calcium ion binding
0.56	GO:0030331	estrogen receptor binding
0.36	GO:0042802	identical protein binding
0.36	GO:0016990	arginine deiminase activity
0.34	GO:0034618	arginine binding
0.33	GO:0046983	protein dimerization activity

0.55	GO:0035327	transcriptionally active chromatin
0.48	GO:0005737	cytoplasm
0.39	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0070013	intracellular organelle lumen
0.34	GO:0097708	intracellular vesicle
0.34	GO:0012505	endomembrane system
0.32	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.79

EC:3.5.3.15

GO:0004668

sp|U3NEE3|HNMTL_CHICK
Carnosine N-methyltransferase 2
Search

HNMT

0.96	Histamine N-methyltransferase A

0.62	GO:0032259	methylation
0.58	GO:0001695	histamine catabolic process
0.52	GO:1903955	positive regulation of protein targeting to mitochondrion
0.44	GO:0007420	brain development
0.38	GO:0002347	response to tumor cell
0.38	GO:0035902	response to immobilization stress
0.38	GO:0014075	response to amine
0.38	GO:0042220	response to cocaine
0.38	GO:0051384	response to glucocorticoid
0.38	GO:0070555	response to interleukin-1

0.69	GO:0008170	N-methyltransferase activity
0.48	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.36	GO:0098603	selenol Se-methyltransferase activity

0.43	GO:0043005	neuron projection
0.38	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome

0.69