Queries 17001 to 18000

GO:0016887

tr|Q5ZM26|Q5ZM26_CHICK
Uncharacterized protein
Search

XRCC3

0.91	X-ray repair complementing defective repair in Chinese hamster cells 3

0.74	GO:0071140	resolution of mitotic recombination intermediates
0.73	GO:0001325	formation of extrachromosomal circular DNA
0.73	GO:0090737	telomere maintenance via telomere trimming
0.71	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint
0.69	GO:0000722	telomere maintenance via recombination
0.68	GO:0010824	regulation of centrosome duplication
0.66	GO:0036297	interstrand cross-link repair
0.65	GO:0000724	double-strand break repair via homologous recombination
0.56	GO:0042148	strand invasion
0.56	GO:0090735	DNA repair complex assembly

0.72	GO:0000400	four-way junction DNA binding
0.70	GO:0008094	DNA-dependent ATPase activity
0.64	GO:0008821	crossover junction endodeoxyribonuclease activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0000150	recombinase activity
0.49	GO:0003697	single-stranded DNA binding
0.49	GO:0003690	double-stranded DNA binding

0.74	GO:0033065	Rad51C-XRCC3 complex
0.64	GO:0048471	perinuclear region of cytoplasm
0.62	GO:0005657	replication fork
0.57	GO:0005654	nucleoplasm
0.56	GO:0005829	cytosol
0.55	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex
0.51	GO:0005739	mitochondrion

0.64

EC:3.1.22.4

GO:0008821

sp|Q5ZM30|RPR1A_CHICK
Regulation of nuclear pre-mRNA domain-containing protein 1A
Search

RPRD1A

0.94	Regulation of nuclear pre-mRNA domain-containing protein 1A

0.85	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain
0.57	GO:0008284	positive regulation of cell proliferation
0.55	GO:0010564	regulation of cell cycle process
0.55	GO:0045944	positive regulation of transcription by RNA polymerase II
0.42	GO:0042795	snRNA transcription by RNA polymerase II

0.61	GO:0000993	RNA polymerase II core binding
0.57	GO:0042802	identical protein binding

0.75	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
0.56	GO:0005813	centrosome
0.51	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q5ZM31|T170A_CHICK
Transmembrane protein 170A
Search

TMEM170A

0.67	Transmembrane domain-containing protein (Fragment)

0.50	GO:0071786	endoplasmic reticulum tubular network organization
0.47	GO:0051292	nuclear pore complex assembly
0.46	GO:0006998	nuclear envelope organization

0.34

GO:0005515

protein binding

0.45	GO:0005635	nuclear envelope
0.44	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q5ZM33|HP1B3_CHICK
Heterochromatin protein 1-binding protein 3
Search

HP1BP3

0.97	Heterochromatin protein 1-binding protein 3

0.83	GO:0070828	heterochromatin organization
0.78	GO:0006334	nucleosome assembly
0.64	GO:0097298	regulation of nucleus size
0.59	GO:0071456	cellular response to hypoxia
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0042127	regulation of cell proliferation
0.55	GO:0010468	regulation of gene expression
0.34	GO:0006936	muscle contraction

0.74	GO:0003682	chromatin binding
0.54	GO:0003677	DNA binding
0.52	GO:0044877	macromolecular complex binding
0.34	GO:0017022	myosin binding
0.34	GO:0005516	calmodulin binding
0.34	GO:0003779	actin binding

0.73	GO:0000786	nucleosome
0.60	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

tr|Q5ZM34|Q5ZM34_CHICK
Uncharacterized protein
Search

STK17B

0.97	Serine/threonine kinase 17b (Apoptosis-inducing)

0.63	GO:0006468	protein phosphorylation
0.61	GO:2000271	positive regulation of fibroblast apoptotic process
0.47	GO:0035556	intracellular signal transduction
0.43	GO:2000377	regulation of reactive oxygen species metabolic process
0.38	GO:0006915	apoptotic process
0.34	GO:0016567	protein ubiquitination
0.33	GO:0007018	microtubule-based movement

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0003777	microtubule motor activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding
0.32	GO:0016874	ligase activity

0.47	GO:0005634	nucleus
0.39	GO:0043233	organelle lumen
0.37	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.37	GO:0005886	plasma membrane
0.37	GO:0015629	actin cytoskeleton
0.37	GO:0044446	intracellular organelle part
0.33	GO:0015630	microtubule cytoskeleton
0.33	GO:1902494	catalytic complex
0.32	GO:0043234	protein complex

0.32	EC:6	GO:0016874
0.34	KEGG:R03876	GO:0004842

sp|Q5ZM35|TWF2_CHICK
Twinfilin-2
Search

TWF2

0.88	Twinfilin actin binding protein 2

0.79	GO:0030837	negative regulation of actin filament polymerization
0.51	GO:0051239	regulation of multicellular organismal process
0.50	GO:0010592	positive regulation of lamellipodium assembly
0.50	GO:0071300	cellular response to retinoic acid
0.49	GO:0061387	regulation of extent of cell growth
0.49	GO:0010770	positive regulation of cell morphogenesis involved in differentiation
0.48	GO:0043538	regulation of actin phosphorylation
0.48	GO:0030307	positive regulation of cell growth
0.48	GO:0048639	positive regulation of developmental growth
0.47	GO:0071363	cellular response to growth factor stimulus

0.74	GO:0003779	actin binding
0.54	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.53	GO:0045296	cadherin binding
0.50	GO:0005080	protein kinase C binding
0.43	GO:0004713	protein tyrosine kinase activity
0.42	GO:0032403	protein complex binding
0.41	GO:0030554	adenyl nucleotide binding
0.41	GO:0097367	carbohydrate derivative binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0008144	drug binding

0.54	GO:0030175	filopodium
0.53	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0031252	cell leading edge
0.50	GO:0032420	stereocilium
0.50	GO:0120038	plasma membrane bounded cell projection part
0.47	GO:0030427	site of polarized growth
0.45	GO:0030016	myofibril
0.43	GO:0005856	cytoskeleton
0.43	GO:0098590	plasma membrane region
0.43	GO:0005911	cell-cell junction

0.43

GO:0004713

sp|Q5ZM36|IF4A3_CHICK
Eukaryotic initiation factor 4A-III
Search

EIF4A3

0.87	Eukaryotic initiation factor

0.61	GO:0006413	translational initiation
0.53	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.51	GO:0048701	embryonic cranial skeleton morphogenesis
0.48	GO:0006417	regulation of translation
0.48	GO:0034250	positive regulation of cellular amide metabolic process
0.47	GO:0034249	negative regulation of cellular amide metabolic process
0.47	GO:0010501	RNA secondary structure unwinding
0.46	GO:0032270	positive regulation of cellular protein metabolic process
0.46	GO:0008380	RNA splicing
0.46	GO:0048024	regulation of mRNA splicing, via spliceosome

0.65	GO:0004386	helicase activity
0.62	GO:0003743	translation initiation factor activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0008143	poly(A) binding
0.49	GO:0008186	RNA-dependent ATPase activity
0.47	GO:0003729	mRNA binding
0.43	GO:0140098	catalytic activity, acting on RNA

0.51	GO:0071013	catalytic step 2 spliceosome
0.51	GO:0035145	exon-exon junction complex
0.48	GO:0005654	nucleoplasm
0.44	GO:0005730	nucleolus
0.39	GO:0005737	cytoplasm
0.36	GO:0043025	neuronal cell body
0.36	GO:0030425	dendrite
0.30	GO:0016020	membrane

sp|Q5ZM39|BCL6_CHICK
B-cell lymphoma 6 protein homolog
Search

BCL6

0.97	B-cell lymphoma 6 protein homolog

0.60	GO:0042092	type 2 immune response
0.59	GO:0032764	negative regulation of mast cell cytokine production
0.58	GO:0043380	regulation of memory T cell differentiation
0.58	GO:0048294	negative regulation of isotype switching to IgE isotypes
0.58	GO:0045591	positive regulation of regulatory T cell differentiation
0.57	GO:0045629	negative regulation of T-helper 2 cell differentiation
0.57	GO:0002467	germinal center formation
0.57	GO:0000060	protein import into nucleus, translocation
0.56	GO:2000773	negative regulation of cellular senescence
0.56	GO:0035024	negative regulation of Rho protein signal transduction

0.57	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding
0.53	GO:0031490	chromatin DNA binding
0.53	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.51	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.50	GO:0042802	identical protein binding
0.35	GO:0005179	hormone activity
0.34	GO:0046872	metal ion binding

0.51	GO:0005657	replication fork
0.49	GO:0005794	Golgi apparatus
0.48	GO:0005654	nucleoplasm
0.34	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q5ZM41|TEX10_CHICK
Testis-expressed protein 10 homolog
Search

TEX10

0.97	Testis-expressed protein 10

0.37

GO:0006364

rRNA processing

0.36

GO:0005515

protein binding

0.82	GO:0071339	MLL1 complex
0.68	GO:0097344	Rix1 complex
0.46	GO:0005730	nucleolus
0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q5ZM44|CHP1_CHICK
Calcineurin B homologous protein 1
Search

CHP1

0.90	Calcineurin B like proteinous protein 1

0.68	GO:0032417	positive regulation of sodium:proton antiporter activity
0.67	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade
0.63	GO:0042308	negative regulation of protein import into nucleus
0.63	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.62	GO:0051453	regulation of intracellular pH
0.61	GO:0010923	negative regulation of phosphatase activity
0.61	GO:1901214	regulation of neuron death
0.47	GO:0060050	positive regulation of protein glycosylation
0.47	GO:0031953	negative regulation of protein autophosphorylation
0.46	GO:0090314	positive regulation of protein targeting to membrane

0.70	GO:0005509	calcium ion binding
0.63	GO:0048306	calcium-dependent protein binding
0.45	GO:0004860	protein kinase inhibitor activity
0.43	GO:0019900	kinase binding
0.42	GO:0008017	microtubule binding
0.37	GO:0005215	transporter activity
0.37	GO:0015459	potassium channel regulator activity
0.36	GO:0016174	NAD(P)H oxidase activity

0.45	GO:0005886	plasma membrane
0.45	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.43	GO:0030133	transport vesicle
0.42	GO:0000139	Golgi membrane
0.41	GO:0015630	microtubule cytoskeleton
0.41	GO:0005783	endoplasmic reticulum
0.39	GO:0005634	nucleus
0.38	GO:0005925	focal adhesion
0.38	GO:0070062	extracellular exosome
0.38	GO:0005829	cytosol

0.36

EC:1.6.3.1

GO:0016174

sp|Q5ZM45|UBP48_CHICK
Ubiquitin carboxyl-terminal hydrolase 48
Search

USP48

0.95	Ubiquitin carboxyl-terminal hydrolase 48

0.76	GO:0016579	protein deubiquitination
0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.44	GO:1904888	cranial skeletal system development
0.34	GO:0051056	regulation of small GTPase mediated signal transduction
0.34	GO:0043547	positive regulation of GTPase activity

0.79	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.35	GO:0005509	calcium ion binding
0.34	GO:0005096	GTPase activator activity

0.48	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.44	GO:0005739	mitochondrion
0.35	GO:0045121	membrane raft
0.34	GO:0045211	postsynaptic membrane

sp|Q5ZM46|LBH_CHICK
Protein LBH
Search

LBH

0.95	Limb bud and heart development

0.57	GO:1904677	positive regulation of somatic stem cell division
0.57	GO:2000101	regulation of mammary stem cell proliferation
0.57	GO:1904674	positive regulation of somatic stem cell population maintenance
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway
0.55	GO:0010468	regulation of gene expression
0.54	GO:2000737	negative regulation of stem cell differentiation
0.51	GO:0060644	mammary gland epithelial cell differentiation
0.50	GO:0008284	positive regulation of cell proliferation

0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q5ZM48|Q5ZM48_CHICK
Synaptogyrin
Search

SYNGR2

0.88	Synaptogyrin

0.44	GO:0045055	regulated exocytosis
0.42	GO:0032411	positive regulation of transporter activity
0.41	GO:0048499	synaptic vesicle membrane organization
0.40	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.39	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.39	GO:0071310	cellular response to organic substance
0.39	GO:1990823	response to leukemia inhibitory factor
0.38	GO:0060976	coronary vasculature development
0.37	GO:0035904	aorta development
0.37	GO:0000185	activation of MAPKKK activity

0.43	GO:0042169	SH2 domain binding
0.42	GO:0047485	protein N-terminus binding
0.37	GO:0004722	protein serine/threonine phosphatase activity
0.37	GO:0019209	kinase activator activity
0.32	GO:0016301	kinase activity

0.57	GO:0008021	synaptic vesicle
0.50	GO:0031594	neuromuscular junction
0.49	GO:0099501	exocytic vesicle membrane
0.39	GO:0030054	cell junction
0.37	GO:0016607	nuclear speck
0.36	GO:0070062	extracellular exosome
0.35	GO:0005829	cytosol
0.35	GO:0005811	lipid droplet
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

sp|Q5ZM55|FEM1B_CHICK
Protein fem-1 homolog B
Search

FEM1B

0.97	Fem-1 homolog b (C. elegans)

0.87	GO:0060743	epithelial cell maturation involved in prostate gland development
0.86	GO:0060442	branching involved in prostate gland morphogenesis
0.86	GO:2000001	regulation of DNA damage checkpoint
0.85	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.81	GO:0051438	regulation of ubiquitin-protein transferase activity
0.73	GO:0016567	protein ubiquitination
0.50	GO:0006915	apoptotic process
0.40	GO:0043687	post-translational protein modification

0.86	GO:0005123	death receptor binding
0.72	GO:0004842	ubiquitin-protein transferase activity

0.69	GO:0005654	nucleoplasm
0.67	GO:0005829	cytosol

0.72

GO:0004842

tr|Q5ZM56|Q5ZM56_CHICK
Serine/threonine-protein phosphatase 2A activator
Search

PTPA

0.66	Serine/threonine-protein phosphatase 2A activator

0.72	GO:0043085	positive regulation of catalytic activity
0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.55	GO:0035307	positive regulation of protein dephosphorylation
0.53	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.51	GO:0043065	positive regulation of apoptotic process
0.49	GO:0030472	mitotic spindle organization in nucleus

0.84	GO:0019211	phosphatase activator activity
0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.56	GO:0051721	protein phosphatase 2A binding
0.54	GO:0019888	protein phosphatase regulator activity
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0005102	receptor binding
0.44	GO:0016887	ATPase activity
0.41	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0000159	protein phosphatase type 2A complex
0.52	GO:0034704	calcium channel complex
0.49	GO:0005737	cytoplasm
0.49	GO:0005654	nucleoplasm
0.35	GO:0070062	extracellular exosome

0.72

GO:0003755

sp|Q5ZM57|HACD3_CHICK
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase
Search

HACD3

0.70	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase

0.70	GO:0006633	fatty acid biosynthetic process
0.57	GO:0046726	positive regulation by virus of viral protein levels in host cell
0.56	GO:0000038	very long-chain fatty acid metabolic process
0.55	GO:0045070	positive regulation of viral genome replication
0.55	GO:0007254	JNK cascade
0.54	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.54	GO:0007266	Rho protein signal transduction
0.47	GO:0030148	sphingolipid biosynthetic process
0.35	GO:0016601	Rac protein signal transduction
0.35	GO:0043507	positive regulation of JUN kinase activity

0.85	GO:0102158	very-long-chain 3-hydroxyacyl-CoA dehydratase activity
0.85	GO:0102343	3-hydroxy-arachidoyl-CoA dehydratase activity
0.85	GO:0102344	3-hydroxy-behenoyl-CoA dehydratase activity
0.85	GO:0102345	3-hydroxy-lignoceroyl-CoA dehydratase activity
0.59	GO:0018812	3-hydroxyacyl-CoA dehydratase activity
0.48	GO:0019899	enzyme binding
0.34	GO:0005096	GTPase activator activity

0.72	GO:0005789	endoplasmic reticulum membrane
0.52	GO:0031965	nuclear membrane
0.47	GO:0005829	cytosol
0.44	GO:0005739	mitochondrion
0.36	GO:0005925	focal adhesion
0.30	GO:0016021	integral component of membrane

0.85

EC:4.2.1.134

GO:0102343

tr|Q5ZM59|Q5ZM59_CHICK
Phosphohippolin-like protein
Search

FXYD6

0.85	FXYD domain-containing ion transport regulator

0.60	GO:0034220	ion transmembrane transport
0.53	GO:2000649	regulation of sodium ion transmembrane transporter activity
0.44	GO:1903275	positive regulation of sodium ion export
0.44	GO:1903276	regulation of sodium ion export across plasma membrane
0.44	GO:0086036	regulation of cardiac muscle cell membrane potential
0.35	GO:1903779	regulation of cardiac conduction

0.69	GO:0005216	ion channel activity
0.53	GO:0017080	sodium channel regulator activity
0.33	GO:0005515	protein binding

0.43	GO:0005887	integral component of plasma membrane
0.42	GO:0042383	sarcolemma

sp|Q5ZM60|CCPG1_CHICK
Cell cycle progression protein 1
Search

CCPG1

0.96	Cell cycle progression protein 1

0.86	GO:1904475	regulation of Ras GTPase binding
0.86	GO:1905097	regulation of guanyl-nucleotide exchange factor activity
0.54	GO:0045787	positive regulation of cell cycle
0.54	GO:0008284	positive regulation of cell proliferation
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.37	GO:0007049	cell cycle
0.36	GO:0003341	cilium movement

0.34

GO:0005515

protein binding

0.30

GO:0016021

integral component of membrane

tr|Q5ZM62|Q5ZM62_CHICK
Uncharacterized protein
Search

ABCF2

0.93	ATP-binding cassette sub-family F member 2

0.34	GO:0015886	heme transport
0.32	GO:0055085	transmembrane transport

0.59	GO:0016887	ATPase activity
0.53	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0015232	heme transporter activity
0.33	GO:0015399	primary active transmembrane transporter activity

0.43	GO:0005739	mitochondrion
0.33	GO:0043190	ATP-binding cassette (ABC) transporter complex
0.33	GO:0031967	organelle envelope

0.59

GO:0016887

tr|Q5ZM64|Q5ZM64_CHICK
Uncharacterized protein
Search

PEX2

0.83	Peroxisomal biogenesis factor 2

0.57	GO:0048147	negative regulation of fibroblast proliferation
0.56	GO:0031648	protein destabilization
0.55	GO:0050680	negative regulation of epithelial cell proliferation
0.55	GO:0000038	very long-chain fatty acid metabolic process
0.54	GO:0016558	protein import into peroxisome matrix
0.52	GO:0000122	negative regulation of transcription by RNA polymerase II
0.52	GO:0006635	fatty acid beta-oxidation
0.37	GO:0045540	regulation of cholesterol biosynthetic process
0.37	GO:0006699	bile acid biosynthetic process
0.37	GO:0042632	cholesterol homeostasis

0.53	GO:0046872	metal ion binding
0.37	GO:0061630	ubiquitin protein ligase activity
0.35	GO:0016874	ligase activity
0.33	GO:0005515	protein binding

0.54	GO:0016593	Cdc73/Paf1 complex
0.54	GO:0005779	integral component of peroxisomal membrane
0.32	GO:0033768	SUMO-targeted ubiquitin ligase complex

0.35

GO:0016874

sp|Q5ZM65|PTSS1_CHICK
Phosphatidylserine synthase 1
Search

PTDSS1

0.92	Phosphatidylserine synthase 1

0.84

GO:0006659

phosphatidylserine biosynthetic process

0.35

GO:0016740

transferase activity

0.47	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:2

GO:0016740

sp|Q5ZM71|SP20H_CHICK
Transcription factor SPT20 homolog
Search

SUPT20H

0.94	Suppressor of Ty 20

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.51	GO:0045722	positive regulation of gluconeogenesis
0.45	GO:1902680	positive regulation of RNA biosynthetic process
0.45	GO:0010628	positive regulation of gene expression
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0007369	gastrulation
0.34	GO:0006914	autophagy

0.76	GO:0003712	transcription cofactor activity
0.33	GO:0005515	protein binding

0.80	GO:0000124	SAGA complex
0.53	GO:0001650	fibrillar center

sp|Q5ZM72|FACR1_CHICK
Fatty acyl-CoA reductase 1
Search

FAR1

0.58	Fatty acyl-CoA reductase

0.62	GO:0006629	lipid metabolic process
0.58	GO:0035336	long-chain fatty-acyl-CoA metabolic process
0.57	GO:0010025	wax biosynthetic process
0.56	GO:0046504	glycerol ether biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.44	GO:0090407	organophosphate biosynthetic process
0.41	GO:0006796	phosphate-containing compound metabolic process
0.33	GO:0000413	protein peptidyl-prolyl isomerization

0.83	GO:0102965	alcohol-forming fatty acyl-CoA reductase activity
0.83	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.53	GO:0005777	peroxisome
0.52	GO:0031903	microbody membrane
0.51	GO:0031301	integral component of organelle membrane
0.35	GO:0031907	microbody lumen

0.33

GO:0003755

sp|Q5ZM73|MIRO1_CHICK
Mitochondrial Rho GTPase 1
Search

RHOT1

0.71	Mitochondrial Rho GTPase

0.73	GO:0007005	mitochondrion organization
0.53	GO:1905710	positive regulation of membrane permeability
0.53	GO:0047497	mitochondrion transport along microtubule
0.50	GO:0097190	apoptotic signaling pathway
0.48	GO:0006839	mitochondrial transport
0.45	GO:0019725	cellular homeostasis
0.45	GO:0061024	membrane organization
0.40	GO:0034640	establishment of mitochondrion localization by microtubule attachment
0.39	GO:1902513	regulation of organelle transport along microtubule
0.38	GO:0046928	regulation of neurotransmitter secretion

0.69	GO:0005509	calcium ion binding
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.81	GO:0031307	integral component of mitochondrial outer membrane
0.33	GO:0005829	cytosol
0.33	GO:0005840	ribosome
0.32	GO:0005886	plasma membrane

sp|Q5ZM74|RN141_CHICK
RING finger protein 141
Search

RNF141

0.74	RING finger protein 141

0.84	GO:0051865	protein autoubiquitination
0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression

0.73	GO:0004842	ubiquitin-protein transferase activity
0.53	GO:0003677	DNA binding
0.41	GO:0046872	metal ion binding
0.33	GO:0004386	helicase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.31	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.73

GO:0004842

tr|Q5ZM76|Q5ZM76_CHICK
Uncharacterized protein
Search

FUBP3

0.95	Far upstream element binding protein 3

0.51	GO:0006366	transcription by RNA polymerase II
0.51	GO:0045944	positive regulation of transcription by RNA polymerase II

0.59	GO:0003723	RNA binding
0.54	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0003697	single-stranded DNA binding
0.33	GO:0005515	protein binding

0.44	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q5ZM83|MIRO2_CHICK
Mitochondrial Rho GTPase 2
Search

RHOT2

0.72	Mitochondrial Rho GTPase

0.71	GO:0007005	mitochondrion organization
0.59	GO:1905710	positive regulation of membrane permeability
0.59	GO:0047497	mitochondrion transport along microtubule
0.55	GO:0097190	apoptotic signaling pathway
0.53	GO:0006839	mitochondrial transport
0.48	GO:0019725	cellular homeostasis
0.48	GO:0061024	membrane organization
0.39	GO:0034640	establishment of mitochondrion localization by microtubule attachment
0.38	GO:1902513	regulation of organelle transport along microtubule
0.37	GO:0046928	regulation of neurotransmitter secretion

0.68	GO:0005509	calcium ion binding
0.66	GO:0003924	GTPase activity
0.64	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.78	GO:0031307	integral component of mitochondrial outer membrane
0.46	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.34	GO:0019866	organelle inner membrane
0.33	GO:0005886	plasma membrane
0.33	GO:0005840	ribosome

sp|Q5ZM86|CCD50_CHICK
Coiled-coil domain-containing protein 50
Search

CCDC50

0.96	Coiled-coil domain-containing protein 50

0.81

GO:0007605

sensory perception of sound

0.79

GO:0031625

ubiquitin protein ligase binding

0.68	GO:0005829	cytosol
0.59	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

sp|Q5ZM88|ASXL2_CHICK
Putative Polycomb group protein ASXL2
Search

ASXL2

0.94	Putative Polycomb group protein ASXL2

0.54	GO:0006351	transcription, DNA-templated
0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.42	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway
0.41	GO:0045600	positive regulation of fat cell differentiation
0.40	GO:1902466	positive regulation of histone H3-K27 trimethylation
0.39	GO:1900159	positive regulation of bone mineralization involved in bone maturation
0.39	GO:0007512	adult heart development
0.38	GO:1902680	positive regulation of RNA biosynthetic process

0.54	GO:0003677	DNA binding
0.42	GO:0042975	peroxisome proliferator activated receptor binding
0.37	GO:0046872	metal ion binding

0.40	GO:0005634	nucleus
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.35	GO:0005694	chromosome

tr|Q5ZM89|Q5ZM89_CHICK
Uncharacterized protein
Search

COMMD5

0.97	COMM domain-containing protein 5

0.44	GO:0072158	proximal tubule morphogenesis
0.41	GO:0030858	positive regulation of epithelial cell differentiation
0.41	GO:0006351	transcription, DNA-templated
0.41	GO:0030307	positive regulation of cell growth
0.41	GO:0007050	cell cycle arrest
0.41	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression

0.37

GO:0005515

protein binding

0.67	GO:0005654	nucleoplasm
0.66	GO:0005829	cytosol

sp|Q5ZM91|KAP0_CHICK
cAMP-dependent protein kinase type I-alpha regulatory subunit
Search

PRKAR1A

0.97	cAMP-dependent protein kinase type I-alpha regulatory subunit

0.75	GO:0045859	regulation of protein kinase activity
0.57	GO:0046007	negative regulation of activated T cell proliferation
0.55	GO:0060038	cardiac muscle cell proliferation
0.54	GO:0033673	negative regulation of kinase activity
0.54	GO:0045214	sarcomere organization
0.54	GO:0001707	mesoderm formation
0.52	GO:0001933	negative regulation of protein phosphorylation
0.51	GO:0016310	phosphorylation
0.40	GO:0051445	regulation of meiotic cell cycle
0.39	GO:0007611	learning or memory

0.84	GO:0008603	cAMP-dependent protein kinase regulator activity
0.83	GO:0030552	cAMP binding
0.58	GO:0034236	protein kinase A catalytic subunit binding
0.58	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.52	GO:0016301	kinase activity
0.52	GO:0031625	ubiquitin protein ligase binding
0.51	GO:0019904	protein domain specific binding
0.34	GO:0042802	identical protein binding
0.33	GO:0004888	transmembrane signaling receptor activity
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.83	GO:0005952	cAMP-dependent protein kinase complex
0.55	GO:0001772	immunological synapse
0.54	GO:0031588	nucleotide-activated protein kinase complex
0.54	GO:0044853	plasma membrane raft
0.53	GO:0031594	neuromuscular junction
0.53	GO:0005930	axoneme
0.35	GO:0097546	ciliary base
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.32

GO:0016773

tr|Q5ZM93|Q5ZM93_CHICK
Uncharacterized protein
Search

SEP15

0.96	Selenoprotein F

0.65	GO:0051084	'de novo' posttranslational protein folding
0.53	GO:0035092	sperm chromatin condensation
0.45	GO:0098869	cellular oxidant detoxification

0.60	GO:0008430	selenium binding
0.50	GO:0008379	thioredoxin peroxidase activity
0.48	GO:0005515	protein binding

0.84	GO:0005788	endoplasmic reticulum lumen
0.58	GO:0070062	extracellular exosome

0.50

EC:1.11.1

GO:0008379

sp|Q5ZM96|QTRT2_CHICK
Queuine tRNA-ribosyltransferase accessory subunit 2
Search

QTRT2

0.79	Queuine tRNA-ribosyltransferase accessory subunit 2

0.70	GO:0101030	tRNA-guanine transglycosylation
0.45	GO:0008616	queuosine biosynthetic process

0.77	GO:0008479	queuine tRNA-ribosyltransferase activity
0.52	GO:0042803	protein homodimerization activity
0.52	GO:0046982	protein heterodimerization activity
0.49	GO:0046872	metal ion binding

0.68	GO:0005741	mitochondrial outer membrane
0.43	GO:0043234	protein complex

0.77

EC:2.4.2.29

GO:0008479

sp|Q5ZM98|GRP75_CHICK
Stress-70 protein, mitochondrial
Search

HSPA9

0.83	Stress-70 protein, mitochondrial

0.68	GO:0006457	protein folding
0.63	GO:1902037	negative regulation of hematopoietic stem cell differentiation
0.62	GO:0045647	negative regulation of erythrocyte differentiation
0.59	GO:0030218	erythrocyte differentiation
0.55	GO:0006611	protein export from nucleus
0.53	GO:0016226	iron-sulfur cluster assembly
0.40	GO:0071345	cellular response to cytokine stimulus
0.40	GO:0060548	negative regulation of cell death
0.40	GO:0097068	response to thyroxine
0.40	GO:0070671	response to interleukin-12

0.70	GO:0051082	unfolded protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0031625	ubiquitin protein ligase binding
0.39	GO:0017134	fibroblast growth factor binding
0.37	GO:0031072	heat shock protein binding
0.37	GO:0051087	chaperone binding
0.36	GO:0003723	RNA binding

0.54	GO:0042645	mitochondrial nucleoid
0.54	GO:0043209	myelin sheath
0.46	GO:0005730	nucleolus
0.42	GO:0031012	extracellular matrix
0.41	GO:0005925	focal adhesion
0.41	GO:0070062	extracellular exosome

sp|Q5ZMA2|PRP19_CHICK
Pre-mRNA-processing factor 19
Search

PRPF19

0.91	Pre-mRNA-processing factor 19

0.69	GO:0016567	protein ubiquitination
0.57	GO:0048711	positive regulation of astrocyte differentiation
0.56	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.56	GO:0072422	signal transduction involved in DNA damage checkpoint
0.56	GO:0000244	spliceosomal tri-snRNP complex assembly
0.55	GO:0001833	inner cell mass cell proliferation
0.54	GO:0045665	negative regulation of neuron differentiation
0.54	GO:0000245	spliceosomal complex assembly
0.53	GO:0006303	double-strand break repair via nonhomologous end joining
0.51	GO:0010498	proteasomal protein catabolic process

0.70	GO:0004842	ubiquitin-protein transferase activity
0.52	GO:0061659	ubiquitin-like protein ligase activity
0.50	GO:0042802	identical protein binding

0.57	GO:0000974	Prp19 complex
0.56	GO:0005662	DNA replication factor A complex
0.55	GO:0071007	U2-type catalytic step 2 spliceosome
0.55	GO:0035861	site of double-strand break
0.54	GO:0005811	lipid droplet
0.53	GO:0016607	nuclear speck
0.48	GO:0071006	U2-type catalytic step 1 spliceosome
0.40	GO:0005819	spindle
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.70

GO:0004842

sp|Q5ZMA3|RBM24_CHICK
RNA-binding protein 24
Search

RBM24

0.91	RNA binding motif protein 24

0.63	GO:0051153	regulation of striated muscle cell differentiation
0.56	GO:0043488	regulation of mRNA stability
0.47	GO:0003228	atrial cardiac muscle tissue development
0.47	GO:0048702	embryonic neurocranium morphogenesis
0.46	GO:0001947	heart looping
0.46	GO:0001756	somitogenesis
0.45	GO:0007519	skeletal muscle tissue development
0.44	GO:0110020	regulation of actomyosin structure organization
0.44	GO:0043484	regulation of RNA splicing
0.44	GO:0072358	cardiovascular system development

0.58	GO:0003723	RNA binding
0.34	GO:0003779	actin binding
0.32	GO:0042802	identical protein binding

0.48	GO:0005829	cytosol
0.48	GO:0005654	nucleoplasm
0.33	GO:0014069	postsynaptic density

sp|Q5ZMA6|NADE_CHICK
Glutamine-dependent NAD(+) synthetase
Search

NADSYN1

0.57	Glutamine-dependent NAD(+) synthetase

0.73	GO:0009435	NAD biosynthetic process
0.36	GO:0051209	release of sequestered calcium ion into cytosol
0.33	GO:0006633	fatty acid biosynthetic process

0.79	GO:0003952	NAD+ synthase (glutamine-hydrolyzing) activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0004359	glutaminase activity
0.37	GO:0072345	NAADP-sensitive calcium-release channel activity
0.36	GO:0005245	voltage-gated calcium channel activity
0.34	GO:0008795	NAD+ synthase activity
0.33	GO:0004075	biotin carboxylase activity
0.33	GO:0003989	acetyl-CoA carboxylase activity

0.46	GO:0005829	cytosol
0.41	GO:0005634	nucleus
0.36	GO:0005765	lysosomal membrane
0.30	GO:0016021	integral component of membrane

0.79

EC:6.3.5.1

GO:0003952

tr|Q5ZMA7|Q5ZMA7_CHICK
Uncharacterized protein
Search

STK26

0.96	Serine/threonine-protein kinase 26

0.63	GO:0006468	protein phosphorylation
0.55	GO:0030033	microvillus assembly
0.55	GO:0042542	response to hydrogen peroxide
0.54	GO:1903205	regulation of hydrogen peroxide-induced cell death
0.54	GO:0030336	negative regulation of cell migration
0.52	GO:0009267	cellular response to starvation
0.51	GO:0042981	regulation of apoptotic process
0.48	GO:0000185	activation of MAPKKK activity
0.47	GO:0031098	stress-activated protein kinase signaling cascade
0.46	GO:0048699	generation of neurons

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0042803	protein homodimerization activity
0.46	GO:0005057	signal transducer activity, downstream of receptor
0.44	GO:0000287	magnesium ion binding
0.39	GO:0045296	cadherin binding

0.52	GO:0016324	apical plasma membrane
0.51	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005798	Golgi-associated vesicle
0.48	GO:0005794	Golgi apparatus
0.48	GO:0005829	cytosol
0.38	GO:0005730	nucleolus
0.37	GO:0070062	extracellular exosome
0.37	GO:0098588	bounding membrane of organelle
0.36	GO:0031984	organelle subcompartment
0.34	GO:0012506	vesicle membrane

tr|Q5ZMB1|Q5ZMB1_CHICK
Uncharacterized protein
Search

NCOA4

0.96	Nuclear receptor coactivator 4

0.84	GO:0006622	protein targeting to lysosome
0.67	GO:0006879	cellular iron ion homeostasis
0.42	GO:0009725	response to hormone
0.39	GO:0008584	male gonad development
0.38	GO:0030150	protein import into mitochondrial matrix
0.38	GO:0030522	intracellular receptor signaling pathway
0.37	GO:0071396	cellular response to lipid
0.37	GO:0071407	cellular response to organic cyclic compound
0.37	GO:0071495	cellular response to endogenous stimulus
0.37	GO:0045893	positive regulation of transcription, DNA-templated

0.39	GO:0050681	androgen receptor binding
0.38	GO:0003713	transcription coactivator activity
0.38	GO:0004252	serine-type endopeptidase activity
0.36	GO:0004649	poly(ADP-ribose) glycohydrolase activity
0.34	GO:0004872	receptor activity

0.84	GO:0044754	autolysosome
0.55	GO:0005739	mitochondrion
0.38	GO:0031301	integral component of organelle membrane
0.35	GO:0098796	membrane protein complex
0.35	GO:0019866	organelle inner membrane
0.35	GO:0005634	nucleus
0.35	GO:0005576	extracellular region

0.38

GO:0004252

sp|Q5ZMB2|HEBP1_CHICK
Heme-binding protein 1
Search

HEBP1

0.97	Heme-binding protein 1

0.48	GO:0007623	circadian rhythm
0.46	GO:0007186	G-protein coupled receptor signaling pathway
0.45	GO:0042168	heme metabolic process

0.62	GO:0020037	heme binding
0.38	GO:0004930	G-protein coupled receptor activity

0.55	GO:0070062	extracellular exosome
0.49	GO:0005829	cytosol
0.45	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

sp|Q5ZMB7|PNRC2_CHICK
Proline-rich nuclear receptor coactivator 2
Search

PNRC2

0.97	LOW QUALITY PROTEIN: proline-rich nuclear receptor coactivator 2

0.77	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.51	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.34

GO:0005515

protein binding

0.55	GO:0000932	P-body
0.47	GO:0005794	Golgi apparatus
0.46	GO:0005654	nucleoplasm
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|Q5ZMB8|Q5ZMB8_CHICK
Uncharacterized protein
Search

PSMC2

0.80	26S proteasome regulatory subunit 7

0.78	GO:1901800	positive regulation of proteasomal protein catabolic process
0.67	GO:0030163	protein catabolic process
0.55	GO:0006508	proteolysis
0.51	GO:0043632	modification-dependent macromolecule catabolic process
0.47	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.45	GO:0034976	response to endoplasmic reticulum stress
0.44	GO:0010243	response to organonitrogen compound
0.43	GO:0044267	cellular protein metabolic process
0.36	GO:0001649	osteoblast differentiation
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition

0.79	GO:0036402	proteasome-activating ATPase activity
0.53	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0008233	peptidase activity
0.46	GO:0017025	TBP-class protein binding
0.32	GO:0046872	metal ion binding

0.57	GO:1905369	endopeptidase complex
0.53	GO:0036464	cytoplasmic ribonucleoprotein granule
0.49	GO:0005829	cytosol
0.48	GO:0043234	protein complex
0.42	GO:0031981	nuclear lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.35	GO:0043197	dendritic spine
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.50

GO:0008233

tr|Q5ZMB9|Q5ZMB9_CHICK
Tyrosine-protein kinase
Search

LYN

0.58	Tyrosine-protein kinase

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.59	GO:0070666	regulation of mast cell proliferation
0.58	GO:2000670	positive regulation of dendritic cell apoptotic process
0.57	GO:0002513	tolerance induction to self antigen
0.57	GO:0002774	Fc receptor mediated inhibitory signaling pathway
0.57	GO:0002431	Fc receptor mediated stimulatory signaling pathway
0.56	GO:0034136	negative regulation of toll-like receptor 2 signaling pathway
0.56	GO:0002576	platelet degranulation
0.56	GO:0002688	regulation of leukocyte chemotaxis
0.56	GO:0030889	negative regulation of B cell proliferation

0.80	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.57	GO:0140031	phosphorylation-dependent protein binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0046875	ephrin receptor binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0044325	ion channel binding
0.50	GO:0017124	SH3 domain binding
0.48	GO:0032403	protein complex binding

0.51	GO:0045121	membrane raft
0.50	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005794	Golgi apparatus
0.45	GO:0005634	nucleus
0.45	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.38	GO:0070013	intracellular organelle lumen
0.36	GO:0044446	intracellular organelle part
0.35	GO:0034666	integrin alpha2-beta1 complex
0.35	GO:0042629	mast cell granule
0.35	GO:0014069	postsynaptic density

0.80

GO:0004715

sp|Q5ZMC0|EDF1_CHICK
Endothelial differentiation-related factor 1 homolog
Search

EDF1

0.96	Endothelial differentiation-related factor 1 isoform alpha

0.54	GO:0043388	positive regulation of DNA binding
0.42	GO:2001141	regulation of RNA biosynthetic process
0.37	GO:0030154	cell differentiation
0.37	GO:0007275	multicellular organism development
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.35	GO:0003158	endothelium development
0.34	GO:0019216	regulation of lipid metabolic process
0.34	GO:0051254	positive regulation of RNA metabolic process

0.63	GO:0043565	sequence-specific DNA binding
0.51	GO:0003713	transcription coactivator activity
0.38	GO:0005516	calmodulin binding
0.36	GO:0004402	histone acetyltransferase activity
0.34	GO:0008168	methyltransferase activity
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003723	RNA binding

0.51	GO:0005669	transcription factor TFIID complex
0.48	GO:0005730	nucleolus
0.46	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome

0.36

GO:0004402

tr|Q5ZMC1|Q5ZMC1_CHICK
Uncharacterized protein
Search

DDX19B

0.81	ATP-dependent RNA helicase DDX19B

0.41	GO:0010501	RNA secondary structure unwinding
0.39	GO:0008380	RNA splicing
0.37	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.37	GO:0051028	mRNA transport
0.37	GO:0006405	RNA export from nucleus
0.36	GO:0060255	regulation of macromolecule metabolic process

0.66	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.39	GO:0008186	RNA-dependent ATPase activity
0.37	GO:0140098	catalytic activity, acting on RNA
0.35	GO:0005515	protein binding

0.41	GO:0071013	catalytic step 2 spliceosome
0.39	GO:0005730	nucleolus
0.37	GO:0070062	extracellular exosome
0.37	GO:0031965	nuclear membrane
0.37	GO:0005643	nuclear pore
0.34	GO:0005737	cytoplasm

sp|Q5ZMC2|MYO1G_CHICK
Unconventional myosin-Ig
Search

0.95	Unconventional myosin-Ig

0.74	GO:0007018	microtubule-based movement
0.54	GO:0071976	cell gliding
0.53	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.52	GO:0072678	T cell migration
0.52	GO:0002456	T cell mediated immunity
0.50	GO:0010923	negative regulation of phosphatase activity
0.48	GO:0031589	cell-substrate adhesion
0.47	GO:0006887	exocytosis
0.43	GO:0051641	cellular localization
0.39	GO:0098927	vesicle-mediated transport between endosomal compartments

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.74	GO:0003779	actin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.51	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.50	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.47	GO:0019904	protein domain specific binding

0.77	GO:0016459	myosin complex
0.52	GO:0120025	plasma membrane bounded cell projection
0.52	GO:0001891	phagocytic cup
0.50	GO:0031256	leading edge membrane
0.49	GO:0005903	brush border
0.48	GO:0043209	myelin sheath
0.48	GO:0043025	neuronal cell body
0.39	GO:0031982	vesicle
0.38	GO:0016323	basolateral plasma membrane
0.38	GO:0043230	extracellular organelle

sp|Q5ZMC3|WSDU1_CHICK
WD repeat, SAM and U-box domain-containing protein 1
Search

WDSUB1

0.96	WD repeat, sterile alpha motif and U-box domain containing 1

0.72

GO:0016567

protein ubiquitination

0.72	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0003677	DNA binding
0.38	GO:0046872	metal ion binding

0.40	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.72

GO:0004842

tr|Q5ZMC5|Q5ZMC5_CHICK
Uncharacterized protein
Search

ORC1

0.86	LOW QUALITY PROTEIN: origin recognition complex subunit 1

0.44	GO:0006270	DNA replication initiation
0.41	GO:0051301	cell division
0.40	GO:0001878	response to yeast
0.39	GO:0040014	regulation of multicellular organism growth
0.38	GO:0043009	chordate embryonic development
0.35	GO:0070318	positive regulation of G0 to G1 transition
0.35	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle
0.34	GO:0048661	positive regulation of smooth muscle cell proliferation

0.74	GO:0003682	chromatin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003677	DNA binding
0.34	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity
0.32	GO:0016740	transferase activity

0.54	GO:0005664	nuclear origin of replication recognition complex
0.52	GO:0000784	nuclear chromosome, telomeric region
0.48	GO:0005730	nucleolus
0.46	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.33	GO:0005654	nucleoplasm
0.33	GO:1905369	endopeptidase complex

0.32

GO:0016787

sp|Q5ZMC6|GSKIP_CHICK
GSK3-beta interaction protein
Search

GSKIP

0.97	GSK3-beta interaction protein isoform X2

0.82	GO:0060828	regulation of canonical Wnt signaling pathway
0.42	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress
0.41	GO:0030177	positive regulation of Wnt signaling pathway
0.40	GO:0006469	negative regulation of protein kinase activity

0.85	GO:0051018	protein kinase A binding
0.41	GO:0004860	protein kinase inhibitor activity

0.37	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

sp|Q5ZMC9|NDE1_CHICK
Nuclear distribution protein nudE homolog 1
Search

NDE1

0.86	Nuclear distribution protein nudE like protein 1

0.84	GO:2000574	regulation of microtubule motor activity
0.62	GO:0007100	mitotic centrosome separation
0.59	GO:0060052	neurofilament cytoskeleton organization
0.54	GO:0007399	nervous system development
0.46	GO:0047496	vesicle transport along microtubule
0.46	GO:0051298	centrosome duplication
0.46	GO:0000132	establishment of mitotic spindle orientation
0.45	GO:0051303	establishment of chromosome localization
0.44	GO:0007020	microtubule nucleation
0.44	GO:0051642	centrosome localization

0.44	GO:0008017	microtubule binding
0.41	GO:0042802	identical protein binding
0.37	GO:0019904	protein domain specific binding
0.35	GO:0043014	alpha-tubulin binding
0.35	GO:0048487	beta-tubulin binding

0.47	GO:0031616	spindle pole centrosome
0.44	GO:0000776	kinetochore
0.42	GO:0005871	kinesin complex
0.42	GO:0045202	synapse
0.41	GO:0005874	microtubule
0.39	GO:0097610	cell surface furrow
0.38	GO:0032155	cell division site part
0.38	GO:0000779	condensed chromosome, centromeric region
0.35	GO:0060053	neurofilament cytoskeleton
0.35	GO:0005737	cytoplasm

sp|Q5ZMD1|1433T_CHICK
14-3-3 protein theta
Search

YWHAQ

0.97	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta

0.48	GO:0007264	small GTPase mediated signal transduction
0.48	GO:0045892	negative regulation of transcription, DNA-templated
0.47	GO:0006605	protein targeting
0.39	GO:0034765	regulation of ion transmembrane transport
0.39	GO:0034763	negative regulation of transmembrane transport
0.39	GO:0043271	negative regulation of ion transport
0.38	GO:0090168	Golgi reassembly
0.38	GO:0051683	establishment of Golgi localization
0.37	GO:0021762	substantia nigra development
0.37	GO:0010941	regulation of cell death

0.77	GO:0019904	protein domain specific binding
0.54	GO:0047485	protein N-terminus binding
0.50	GO:0042802	identical protein binding
0.42	GO:0044325	ion channel binding
0.39	GO:0004497	monooxygenase activity
0.39	GO:0071889	14-3-3 protein binding
0.38	GO:0008022	protein C-terminus binding
0.37	GO:0008134	transcription factor binding
0.37	GO:0019899	enzyme binding
0.37	GO:0045296	cadherin binding

0.43	GO:0043234	protein complex
0.39	GO:0005737	cytoplasm
0.36	GO:0005925	focal adhesion
0.36	GO:0031982	vesicle
0.36	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space
0.34	GO:0005634	nucleus
0.34	GO:0031090	organelle membrane
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005886	plasma membrane

0.34

GO:0004222

sp|Q5ZMD2|ANKY2_CHICK
Ankyrin repeat and MYND domain-containing protein 2
Search

ANKMY2

0.96	Ankyrin repeat and MYND domain-containing protein 2

0.70	GO:0008589	regulation of smoothened signaling pathway
0.36	GO:0008299	isoprenoid biosynthetic process

0.64	GO:0019899	enzyme binding
0.37	GO:0046872	metal ion binding
0.36	GO:0070567	cytidylyltransferase activity

0.44

GO:0005929

cilium

sp|Q5ZMD4|TRI59_CHICK
Tripartite motif-containing protein 59
Search

TRIM59

0.86	Tripartite motif-containing protein 59

0.56	GO:0046597	negative regulation of viral entry into host cell
0.54	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.51	GO:0045087	innate immune response
0.50	GO:0060271	cilium assembly
0.49	GO:0016567	protein ubiquitination
0.38	GO:0009887	animal organ morphogenesis
0.38	GO:0009888	tissue development
0.38	GO:2000051	negative regulation of non-canonical Wnt signaling pathway
0.37	GO:0060041	retina development in camera-type eye
0.37	GO:0045880	positive regulation of smoothened signaling pathway

0.63	GO:0008270	zinc ion binding
0.50	GO:0061630	ubiquitin protein ligase activity
0.35	GO:0016874	ligase activity
0.34	GO:0005515	protein binding
0.32	GO:0043142	single-stranded DNA-dependent ATPase activity

0.51	GO:0030992	intraciliary transport particle B
0.51	GO:0005929	cilium
0.48	GO:0005813	centrosome
0.48	GO:0005783	endoplasmic reticulum
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.32	GO:0097505	Rad6-Rad18 complex
0.31	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0016874

sp|Q5ZMD6|H2AZ_CHICK
Histone H2A.Z
Search

tr|Q5ZME1|Q5ZME1_CHICK
Uncharacterized protein
Search

HNRNPA2B1

0.78	Heterogeneous nuclear ribonucleoprotein A2 homolog 1

0.79	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.75	GO:0051028	mRNA transport
0.74	GO:0006405	RNA export from nucleus
0.69	GO:0006397	mRNA processing
0.60	GO:1990428	miRNA transport
0.58	GO:0031053	primary miRNA processing
0.56	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.51	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
0.51	GO:0000122	negative regulation of transcription by RNA polymerase II
0.36	GO:1905661	regulation of telomerase RNA reverse transcriptase activity

0.59	GO:1990247	N6-methyladenosine-containing RNA binding
0.57	GO:0035198	miRNA binding
0.56	GO:0097157	pre-mRNA intronic binding
0.56	GO:0043047	single-stranded telomeric DNA binding
0.55	GO:0003730	mRNA 3'-UTR binding
0.35	GO:0042802	identical protein binding
0.35	GO:1990715	mRNA CDS binding
0.34	GO:0001069	regulatory region RNA binding
0.34	GO:0070182	DNA polymerase binding

0.60	GO:0019013	viral nucleocapsid
0.57	GO:0030529	intracellular ribonucleoprotein complex
0.54	GO:0070062	extracellular exosome
0.49	GO:0005654	nucleoplasm
0.45	GO:1902494	catalytic complex
0.39	GO:0005737	cytoplasm
0.35	GO:0016363	nuclear matrix
0.35	GO:0000781	chromosome, telomeric region
0.34	GO:0043204	perikaryon
0.33	GO:0043005	neuron projection

sp|Q5ZME2|MDHC_CHICK
Malate dehydrogenase, cytoplasmic
Search

MDH1

0.46	Malate dehydrogenase

0.78	GO:0006108	malate metabolic process
0.70	GO:0006099	tricarboxylic acid cycle
0.60	GO:0005975	carbohydrate metabolic process
0.48	GO:0006734	NADH metabolic process
0.46	GO:0006107	oxaloacetate metabolic process
0.33	GO:0044283	small molecule biosynthetic process
0.32	GO:1901576	organic substance biosynthetic process

0.78	GO:0030060	L-malate dehydrogenase activity
0.36	GO:0051287	NAD binding
0.36	GO:0047860	diiodophenylpyruvate reductase activity
0.34	GO:0004470	malic enzyme activity
0.33	GO:0005515	protein binding

0.49	GO:0043209	myelin sheath
0.43	GO:0005739	mitochondrion
0.42	GO:0005829	cytosol
0.36	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

0.78	EC:1.1.1.37	GO:0030060
0.36	KEGG:R03431	GO:0047860

sp|Q5ZME8|SMU1_CHICK
WD40 repeat-containing protein SMU1
Search

SMU1

0.94	DNA replication regulator and spliceosomal factor

0.79	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.69	GO:0008380	RNA splicing
0.66	GO:0006397	mRNA processing
0.45	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.39	GO:0006468	protein phosphorylation

0.47	GO:0016905	myosin heavy chain kinase activity
0.44	GO:0031683	G-protein beta/gamma-subunit complex binding
0.41	GO:0003924	GTPase activity
0.40	GO:0032550	purine ribonucleoside binding
0.40	GO:0019001	guanyl nucleotide binding
0.40	GO:0004871	signal transducer activity
0.37	GO:0032555	purine ribonucleotide binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.75	GO:0016607	nuclear speck
0.69	GO:0005681	spliceosomal complex
0.47	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.47

EC:2.7.11.7

GO:0016905

tr|Q5ZMF3|Q5ZMF3_CHICK
Deoxycytidine kinase
Search

DCK

0.61	Deoxynucleoside kinase

0.62	GO:0009165	nucleotide biosynthetic process
0.52	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process
0.51	GO:0016310	phosphorylation
0.47	GO:0006220	pyrimidine nucleotide metabolic process
0.35	GO:0046092	deoxycytidine metabolic process
0.35	GO:0046053	dAMP metabolic process
0.34	GO:0043097	pyrimidine nucleoside salvage
0.34	GO:0072522	purine-containing compound biosynthetic process
0.33	GO:0046385	deoxyribose phosphate biosynthetic process
0.33	GO:0009127	purine nucleoside monophosphate biosynthetic process

0.76	GO:0019206	nucleoside kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0042803	protein homodimerization activity
0.36	GO:0032548	pyrimidine deoxyribonucleoside binding
0.33	GO:0000287	magnesium ion binding
0.32	GO:0046982	protein heterodimerization activity
0.31	GO:0003677	DNA binding

0.44	GO:0005634	nucleus
0.34	GO:0005829	cytosol
0.32	GO:0000786	nucleosome

tr|Q5ZMF6|Q5ZMF6_CHICK
Uncharacterized protein
Search

TRAP1

0.82	TNF receptor associated protein 1

0.70	GO:0009386	translational attenuation
0.69	GO:0006457	protein folding
0.68	GO:1901856	negative regulation of cellular respiration
0.62	GO:0006950	response to stress

0.71	GO:0051082	unfolded protein binding
0.60	GO:0019901	protein kinase binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.58	GO:0005759	mitochondrial matrix
0.54	GO:0005654	nucleoplasm
0.50	GO:0031966	mitochondrial membrane
0.50	GO:0019866	organelle inner membrane

tr|Q5ZMF8|Q5ZMF8_CHICK
Uncharacterized protein
Search

LIN9

0.97	Lin-9 DREAM MuvB core complex component

0.67	GO:0007049	cell cycle
0.58	GO:0006351	transcription, DNA-templated
0.41	GO:0051726	regulation of cell cycle
0.35	GO:0071897	DNA biosynthetic process

0.33

GO:0005515

protein binding

0.81	GO:0017053	transcriptional repressor complex
0.47	GO:0005654	nucleoplasm

tr|Q5ZMF9|Q5ZMF9_CHICK
Derlin
Search

DERL1

0.64

Derlin

0.56	GO:0031648	protein destabilization
0.56	GO:0071712	ER-associated misfolded protein catabolic process
0.56	GO:1903513	endoplasmic reticulum to cytosol transport
0.56	GO:0032527	protein exit from endoplasmic reticulum
0.55	GO:0006986	response to unfolded protein
0.55	GO:0032092	positive regulation of protein binding
0.54	GO:0030433	ubiquitin-dependent ERAD pathway
0.53	GO:0031398	positive regulation of protein ubiquitination
0.52	GO:0051260	protein homooligomerization
0.44	GO:0007165	signal transduction

0.57	GO:0042288	MHC class I protein binding
0.57	GO:1990381	ubiquitin-specific protease binding
0.55	GO:0051117	ATPase binding
0.52	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0004872	receptor activity

0.72	GO:0005789	endoplasmic reticulum membrane
0.54	GO:0005791	rough endoplasmic reticulum
0.53	GO:0005769	early endosome
0.52	GO:0005770	late endosome
0.52	GO:0048500	signal recognition particle
0.49	GO:0098588	bounding membrane of organelle
0.45	GO:0098796	membrane protein complex
0.34	GO:0097038	perinuclear endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

sp|Q5ZMG0|DOPD_CHICK
D-dopachrome decarboxylase
Search

DDT

0.97	D-dopachrome tautomerase like

0.76	GO:0050729	positive regulation of inflammatory response
0.61	GO:0042438	melanin biosynthetic process
0.51	GO:0010760	negative regulation of macrophage chemotaxis
0.49	GO:0032760	positive regulation of tumor necrosis factor production
0.48	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.44	GO:0006336	DNA replication-independent nucleosome assembly
0.40	GO:0048839	inner ear development
0.40	GO:0006954	inflammatory response
0.39	GO:0043066	negative regulation of apoptotic process
0.37	GO:0006749	glutathione metabolic process

0.76	GO:0002020	protease binding
0.68	GO:0033981	D-dopachrome decarboxylase activity
0.51	GO:0050178	phenylpyruvate tautomerase activity
0.47	GO:0004167	dopachrome isomerase activity
0.46	GO:0005126	cytokine receptor binding
0.38	GO:0004364	glutathione transferase activity

0.68	GO:0005615	extracellular space
0.47	GO:1903561	extracellular vesicle
0.41	GO:0005737	cytoplasm

0.68	EC:4.1.1.84	GO:0033981
0.68	KEGG:R07313	GO:0033981

sp|Q5ZMG1|UFL1_CHICK
E3 UFM1-protein ligase 1
Search

UFL1

0.94	UFM1 specific ligase 1

0.62	GO:0071569	protein ufmylation
0.60	GO:1902065	response to L-glutamate
0.60	GO:0033146	regulation of intracellular estrogen receptor signaling pathway
0.60	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.59	GO:0060252	positive regulation of glial cell proliferation
0.59	GO:0031397	negative regulation of protein ubiquitination
0.57	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
0.56	GO:0034976	response to endoplasmic reticulum stress
0.53	GO:0032880	regulation of protein localization
0.38	GO:0043066	negative regulation of apoptotic process

0.64	GO:0071568	UFM1 transferase activity
0.57	GO:0016874	ligase activity
0.34	GO:0005515	protein binding

0.53	GO:0043005	neuron projection
0.52	GO:0005783	endoplasmic reticulum
0.51	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.49	GO:0031984	organelle subcompartment
0.45	GO:0043234	protein complex
0.38	GO:0005829	cytosol
0.30	GO:0044425	membrane part

0.57

GO:0016874

tr|Q5ZMG2|Q5ZMG2_CHICK
Claudin
Search

CLDN1

0.67

Claudin

0.59	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.58	GO:0061436	establishment of skin barrier
0.57	GO:0070830	bicellular tight junction assembly
0.56	GO:0051291	protein heterooligomerization
0.53	GO:0051260	protein homooligomerization
0.48	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.48	GO:0044409	entry into host
0.46	GO:0019058	viral life cycle
0.42	GO:0061772	drug transport across blood-nerve barrier
0.42	GO:1903545	cellular response to butyrate

0.62	GO:0005198	structural molecule activity
0.58	GO:0104005	hijacked molecular function
0.50	GO:0042802	identical protein binding
0.32	GO:0016301	kinase activity
0.32	GO:0016787	hydrolase activity
0.32	GO:0046872	metal ion binding

0.81	GO:0005923	bicellular tight junction
0.56	GO:0016328	lateral plasma membrane
0.55	GO:0016323	basolateral plasma membrane
0.54	GO:0016324	apical plasma membrane
0.48	GO:0005887	integral component of plasma membrane
0.36	GO:0016327	apicolateral plasma membrane
0.34	GO:0005737	cytoplasm

0.32

GO:0016787

sp|Q5ZMG5|AROS_CHICK
Active regulator of SIRT1
Search

RPS19BP1

0.96	Active regulator of SIRT1

0.66	GO:0019899	enzyme binding
0.40	GO:0003723	RNA binding

0.73	GO:0005730	nucleolus
0.70	GO:0005654	nucleoplasm
0.63	GO:0005829	cytosol

tr|Q5ZMG6|Q5ZMG6_CHICK
Uncharacterized protein
Search

0.80	lysine-specific demethylase 4C

0.60	GO:0070544	histone H3-K36 demethylation
0.60	GO:0033169	histone H3-K9 demethylation
0.56	GO:1900113	negative regulation of histone H3-K9 trimethylation
0.52	GO:0032259	methylation
0.46	GO:0008284	positive regulation of cell proliferation
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.40	GO:2000036	regulation of stem cell population maintenance
0.39	GO:2000736	regulation of stem cell differentiation
0.39	GO:0001825	blastocyst formation
0.37	GO:0045666	positive regulation of neuron differentiation

0.60	GO:0032454	histone demethylase activity (H3-K9 specific)
0.53	GO:0008168	methyltransferase activity
0.51	GO:0051864	histone demethylase activity (H3-K36 specific)
0.51	GO:0046872	metal ion binding
0.49	GO:0050681	androgen receptor binding
0.43	GO:0019899	enzyme binding
0.36	GO:0003682	chromatin binding

0.60	GO:0005634	nucleus
0.53	GO:0005721	pericentric heterochromatin
0.49	GO:0031974	membrane-enclosed lumen
0.45	GO:0005829	cytosol

0.53

GO:0008168

tr|Q5ZMG7|Q5ZMG7_CHICK
Uncharacterized protein
Search

AP1M1

0.86	AP-1 complex subunit mu-1

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.57	GO:0035646	endosome to melanosome transport
0.56	GO:0032438	melanosome organization
0.43	GO:0048565	digestive tract development
0.42	GO:0048513	animal organ development
0.42	GO:0060322	head development
0.42	GO:0007417	central nervous system development
0.39	GO:2001136	negative regulation of endocytic recycling
0.39	GO:0033363	secretory granule organization

0.36	GO:0008565	protein transporter activity
0.34	GO:0005515	protein binding
0.33	GO:0003887	DNA-directed DNA polymerase activity
0.33	GO:0003676	nucleic acid binding

0.79	GO:0030131	clathrin adaptor complex
0.41	GO:0030665	clathrin-coated vesicle membrane
0.39	GO:0035976	transcription factor AP-1 complex
0.39	GO:0005794	Golgi apparatus
0.38	GO:0030140	trans-Golgi network transport vesicle
0.37	GO:0030658	transport vesicle membrane
0.37	GO:0030120	vesicle coat
0.37	GO:0030660	Golgi-associated vesicle membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0035579	specific granule membrane

0.33

EC:2.7.7.7

GO:0003887

tr|Q5ZMG8|Q5ZMG8_CHICK
Uncharacterized protein
Search

0.89	Rho-related GTP-binding protein RhoG

0.77	GO:0007264	small GTPase mediated signal transduction
0.44	GO:1903078	positive regulation of protein localization to plasma membrane
0.44	GO:0090630	activation of GTPase activity
0.43	GO:1900027	regulation of ruffle assembly
0.43	GO:0060326	cell chemotaxis
0.40	GO:0030036	actin cytoskeleton organization
0.40	GO:0045893	positive regulation of transcription, DNA-templated
0.37	GO:0043312	neutrophil degranulation
0.37	GO:0030168	platelet activation
0.36	GO:0008284	positive regulation of cell proliferation

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.36	GO:0012506	vesicle membrane
0.35	GO:0005886	plasma membrane
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.30	GO:0044425	membrane part

tr|Q5ZMG9|Q5ZMG9_CHICK
Uncharacterized protein
Search

TCP1

0.78	T-complex protein 1 subunit alpha

0.66	GO:0006457	protein folding
0.61	GO:0044053	translocation of peptides or proteins into host cell cytoplasm
0.60	GO:0090670	RNA localization to Cajal body
0.60	GO:2000109	regulation of macrophage apoptotic process
0.59	GO:1904869	regulation of protein localization to Cajal body
0.59	GO:1904851	positive regulation of establishment of protein localization to telomere
0.58	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.58	GO:0051973	positive regulation of telomerase activity
0.57	GO:0007339	binding of sperm to zona pellucida
0.57	GO:0032212	positive regulation of telomere maintenance via telomerase

0.68	GO:0051082	unfolded protein binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0044183	protein binding involved in protein folding
0.34	GO:0003723	RNA binding
0.33	GO:0005216	ion channel activity

0.59	GO:0002199	zona pellucida receptor complex
0.59	GO:0005832	chaperonin-containing T-complex
0.58	GO:0000242	pericentriolar material
0.56	GO:0001669	acrosomal vesicle
0.56	GO:0005720	nuclear heterochromatin
0.55	GO:0043209	myelin sheath
0.54	GO:0044297	cell body
0.51	GO:0005874	microtubule
0.50	GO:0005794	Golgi apparatus
0.37	GO:0070062	extracellular exosome

tr|Q5ZMH0|Q5ZMH0_CHICK
Uncharacterized protein
Search

REXO5

0.97	Exonuclease NEF-sp

0.56	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.33	GO:0002107	generation of mature 3'-end of 5S rRNA generated by RNA polymerase III
0.33	GO:0034476	U5 snRNA 3'-end processing
0.32	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.32	GO:0042780	tRNA 3'-end processing
0.31	GO:0055085	transmembrane transport

0.60	GO:0004527	exonuclease activity
0.57	GO:0003723	RNA binding
0.32	GO:0004540	ribonuclease activity
0.31	GO:0050662	coenzyme binding

0.51	GO:0005730	nucleolus
0.35	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q5ZMH1|SEPT2_CHICK
Septin-2
Search

SEPT2

0.85

Septin-2

0.67	GO:0051301	cell division
0.67	GO:0007049	cell cycle
0.54	GO:0002036	regulation of L-glutamate transport
0.52	GO:0007224	smoothened signaling pathway
0.50	GO:0060271	cilium assembly
0.47	GO:0032880	regulation of protein localization
0.45	GO:0050790	regulation of catalytic activity
0.38	GO:0007283	spermatogenesis
0.37	GO:0030154	cell differentiation
0.36	GO:0007399	nervous system development

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0045296	cadherin binding
0.49	GO:0032947	protein complex scaffold activity
0.45	GO:0030234	enzyme regulator activity
0.36	GO:0042802	identical protein binding
0.34	GO:0003924	GTPase activity

0.53	GO:0097227	sperm annulus
0.53	GO:0060170	ciliary membrane
0.52	GO:0031105	septin complex
0.52	GO:0032391	photoreceptor connecting cilium
0.50	GO:0043209	myelin sheath
0.50	GO:0005930	axoneme
0.49	GO:0009986	cell surface
0.47	GO:0045202	synapse
0.42	GO:0005634	nucleus
0.42	GO:0030496	midbody

tr|Q5ZMH3|Q5ZMH3_CHICK
Uncharacterized protein
Search

ADIPOR2

0.94	Adiponectin receptor protein 2

0.62	GO:0033211	adiponectin-activated signaling pathway
0.57	GO:0061042	vascular wound healing
0.54	GO:0042593	glucose homeostasis
0.42	GO:1901223	negative regulation of NIK/NF-kappaB signaling
0.41	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.41	GO:0046426	negative regulation of JAK-STAT cascade
0.41	GO:0032879	regulation of localization
0.40	GO:0019395	fatty acid oxidation
0.40	GO:0010906	regulation of glucose metabolic process
0.40	GO:0019216	regulation of lipid metabolic process

0.60	GO:0097003	adipokinetic hormone receptor activity
0.60	GO:0055100	adiponectin binding
0.51	GO:0046982	protein heterodimerization activity
0.50	GO:0042802	identical protein binding
0.39	GO:0019901	protein kinase binding
0.33	GO:0046872	metal ion binding

0.47	GO:0031226	intrinsic component of plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q5ZMH6|METL9_CHICK
Methyltransferase-like protein 9
Search

METTL9

0.96	DORA reverse strand protein 1

0.60	GO:0032259	methylation
0.33	GO:0097659	nucleic acid-templated transcription
0.32	GO:0010467	gene expression
0.32	GO:0034645	cellular macromolecule biosynthetic process
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.60	GO:0008168	methyltransferase activity
0.34	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.34	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.33	GO:0005634	nucleus
0.30	GO:0044425	membrane part

0.60

GO:0008168

tr|Q5ZMH7|Q5ZMH7_CHICK
Uncharacterized protein
Search

NFYA

0.67	Nuclear transcription factor Y subunit alpha

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.37	GO:0048511	rhythmic process
0.36	GO:1902680	positive regulation of RNA biosynthetic process
0.36	GO:2000036	regulation of stem cell population maintenance
0.35	GO:2000648	positive regulation of stem cell proliferation
0.35	GO:0006366	transcription by RNA polymerase II
0.34	GO:0045540	regulation of cholesterol biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0001221	transcription cofactor binding

0.82	GO:0016602	CCAAT-binding factor complex
0.46	GO:0032993	protein-DNA complex
0.46	GO:0005654	nucleoplasm

tr|Q5ZMH8|Q5ZMH8_CHICK
Uncharacterized protein
Search

NANS

0.57	N-acetylneuraminic acid synthase a

0.67	GO:0016051	carbohydrate biosynthetic process
0.43	GO:0048706	embryonic skeletal system development
0.36	GO:0006055	CMP-N-acetylneuraminate biosynthetic process

0.54	GO:0047444	N-acylneuraminate-9-phosphate synthase activity
0.37	GO:0050462	N-acetylneuraminate synthase activity
0.37	GO:0008781	N-acylneuraminate cytidylyltransferase activity
0.34	GO:0004565	beta-galactosidase activity

0.44	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.54

EC:2.5.1.57

GO:0047444

tr|Q5ZMH9|Q5ZMH9_CHICK
Uncharacterized protein
Search

NSA2

0.81	TGF beta-inducible nuclear protein 1

0.78	GO:0000470	maturation of LSU-rRNA
0.77	GO:0000460	maturation of 5.8S rRNA

0.38	GO:0003723	RNA binding
0.34	GO:0046872	metal ion binding

0.77	GO:0030687	preribosome, large subunit precursor
0.70	GO:0005730	nucleolus
0.37	GO:0005840	ribosome

tr|Q5ZMI3|Q5ZMI3_CHICK
Uncharacterized protein
Search

TBC1D22A

0.89	TBC1 domain family member 22A

0.64	GO:0031338	regulation of vesicle fusion
0.64	GO:0090630	activation of GTPase activity
0.55	GO:0006886	intracellular protein transport
0.42	GO:1902017	regulation of cilium assembly

0.85	GO:0071889	14-3-3 protein binding
0.63	GO:0042803	protein homodimerization activity
0.62	GO:0017137	Rab GTPase binding
0.60	GO:0005096	GTPase activator activity

0.53	GO:0012505	endomembrane system
0.39	GO:0005622	intracellular

sp|Q5ZMI4|MVP_CHICK
Major vault protein
Search

MVP

0.84	Major vault protein-alpha

0.48	GO:0023051	regulation of signaling
0.42	GO:0031953	negative regulation of protein autophosphorylation
0.42	GO:0061099	negative regulation of protein tyrosine kinase activity
0.41	GO:0038127	ERBB signaling pathway
0.41	GO:0031102	neuron projection regeneration
0.39	GO:0001654	eye development
0.39	GO:0007420	brain development
0.38	GO:0009617	response to bacterium
0.33	GO:0007017	microtubule-based process

0.41	GO:0019903	protein phosphatase binding
0.40	GO:0019901	protein kinase binding
0.39	GO:0042802	identical protein binding

0.61	GO:0030529	intracellular ribonucleoprotein complex
0.49	GO:0005737	cytoplasm
0.46	GO:0005634	nucleus
0.38	GO:0005856	cytoskeleton
0.37	GO:0097708	intracellular vesicle
0.33	GO:0043234	protein complex
0.32	GO:0044446	intracellular organelle part

tr|Q5ZMI5|Q5ZMI5_CHICK
Uncharacterized protein
Search

RAB9A

0.93	Ras-related protein Rab-9A

0.43	GO:0042147	retrograde transport, endosome to Golgi
0.43	GO:0052405	negative regulation by host of symbiont molecular function
0.41	GO:0045921	positive regulation of exocytosis
0.39	GO:0032880	regulation of protein localization
0.38	GO:0015031	protein transport
0.35	GO:0043312	neutrophil degranulation
0.33	GO:0006351	transcription, DNA-templated

0.64	GO:0003924	GTPase activity
0.62	GO:0032550	purine ribonucleoside binding
0.62	GO:0019001	guanyl nucleotide binding
0.52	GO:0032555	purine ribonucleotide binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0042802	identical protein binding

0.43	GO:0045335	phagocytic vesicle
0.42	GO:0030666	endocytic vesicle membrane
0.41	GO:0042470	melanosome
0.40	GO:0005770	late endosome
0.40	GO:0005764	lysosome
0.40	GO:0005829	cytosol
0.38	GO:0000139	Golgi membrane
0.38	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0005886	plasma membrane

tr|Q5ZMJ0|Q5ZMJ0_CHICK
Peptidyl-prolyl cis-trans isomerase
Search

PPIF

0.48	Peptidyl-prolyl cis-trans isomerase

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.67	GO:0006457	protein folding
0.56	GO:0010849	regulation of proton-transporting ATPase activity, rotational mechanism
0.55	GO:2000276	negative regulation of oxidative phosphorylation uncoupler activity
0.55	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.55	GO:1902686	mitochondrial outer membrane permeabilization involved in programmed cell death
0.55	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death
0.54	GO:0090324	negative regulation of oxidative phosphorylation
0.53	GO:0070301	cellular response to hydrogen peroxide
0.53	GO:0071243	cellular response to arsenic-containing substance

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.40	GO:0016018	cyclosporin A binding
0.35	GO:0005515	protein binding
0.33	GO:0003723	RNA binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016301	kinase activity

0.56	GO:0005757	mitochondrial permeability transition pore complex
0.41	GO:0005759	mitochondrial matrix
0.37	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.34	GO:0009533	chloroplast stromal thylakoid
0.33	GO:0031977	thylakoid lumen
0.33	GO:0009535	chloroplast thylakoid membrane

0.72

GO:0003755

sp|Q5ZMJ4|GLPK5_CHICK
Putative glycerol kinase 5
Search

GK5

0.97	Lycerol kinase 5

0.60	GO:0005975	carbohydrate metabolic process
0.56	GO:0016310	phosphorylation
0.47	GO:0006641	triglyceride metabolic process
0.47	GO:0046167	glycerol-3-phosphate biosynthetic process
0.45	GO:0019751	polyol metabolic process
0.40	GO:0046164	alcohol catabolic process
0.37	GO:0044248	cellular catabolic process
0.33	GO:0006814	sodium ion transport
0.33	GO:0006813	potassium ion transport
0.33	GO:0046072	dTDP metabolic process

0.62	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.58	GO:0016301	kinase activity
0.36	GO:0032553	ribonucleotide binding
0.36	GO:0017076	purine nucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0008144	drug binding
0.33	GO:0003924	GTPase activity
0.33	GO:0004527	exonuclease activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0016776	phosphotransferase activity, phosphate group as acceptor

0.40	GO:0005739	mitochondrion
0.34	GO:0005890	sodium:potassium-exchanging ATPase complex

0.62

GO:0016773

tr|Q5ZMJ6|Q5ZMJ6_CHICK
Uncharacterized protein
Search

SLC25A4

0.85	Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 4

0.58	GO:0015866	ADP transport
0.55	GO:0046902	regulation of mitochondrial membrane permeability
0.55	GO:0055085	transmembrane transport
0.53	GO:0060546	negative regulation of necroptotic process
0.52	GO:0015867	ATP transport
0.52	GO:0008637	apoptotic mitochondrial changes
0.45	GO:0010823	negative regulation of mitochondrion organization
0.43	GO:2001234	negative regulation of apoptotic signaling pathway
0.43	GO:0051051	negative regulation of transport
0.42	GO:0008284	positive regulation of cell proliferation

0.57	GO:0022857	transmembrane transporter activity
0.42	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0003723	RNA binding

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.52	GO:0043209	myelin sheath
0.46	GO:0071817	MMXD complex
0.42	GO:0042645	mitochondrial nucleoid
0.39	GO:0045121	membrane raft
0.38	GO:0031301	integral component of organelle membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:0031968	organelle outer membrane

sp|Q5ZMJ7|CIP2A_CHICK
Protein CIP2A homolog
Search

0.10	Cell proliferation-regulating inhibitor of protein phosphatase 2A

0.75	GO:2000179	positive regulation of neural precursor cell proliferation
0.70	GO:0007283	spermatogenesis
0.35	GO:0007018	microtubule-based movement
0.31	GO:0055085	transmembrane transport

0.73	GO:0045296	cadherin binding
0.68	GO:0042803	protein homodimerization activity
0.36	GO:0051015	actin filament binding
0.35	GO:0003777	microtubule motor activity
0.35	GO:0008017	microtubule binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0042626	ATPase activity, coupled to transmembrane movement of substances

0.63	GO:0005829	cytosol
0.52	GO:0005886	plasma membrane
0.35	GO:0016459	myosin complex
0.30	GO:0016021	integral component of membrane

sp|Q5ZMJ9|SRRM1_CHICK
Serine/arginine repetitive matrix protein 1
Search

SRRM1

0.77	Serine and arginine repetitive matrix 1

0.68	GO:0006397	mRNA processing
0.38	GO:0008380	RNA splicing
0.36	GO:0006369	termination of RNA polymerase II transcription
0.35	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.35	GO:0031123	RNA 3'-end processing
0.35	GO:0051028	mRNA transport
0.35	GO:0006405	RNA export from nucleus

0.36	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.34	GO:0003677	DNA binding

0.53	GO:0016607	nuclear speck
0.51	GO:0071013	catalytic step 2 spliceosome
0.39	GO:0016363	nuclear matrix
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|Q5ZMK0|Q5ZMK0_CHICK
Uncharacterized protein
Search

CTSO

0.94	Cathepsin O

0.60	GO:0006508	proteolysis
0.43	GO:0044257	cellular protein catabolic process

0.71	GO:0008234	cysteine-type peptidase activity
0.41	GO:0004175	endopeptidase activity

0.46	GO:0005764	lysosome
0.44	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.71

GO:0008234

tr|Q5ZMK3|Q5ZMK3_CHICK
Uncharacterized protein
Search

SCCPDH

0.51	Saccharopine dehydrogenase a

0.52	GO:0055114	oxidation-reduction process
0.35	GO:0002576	platelet degranulation

0.53

GO:0016491

oxidoreductase activity

0.53	GO:0030496	midbody
0.53	GO:0005811	lipid droplet
0.43	GO:0005739	mitochondrion
0.35	GO:0031093	platelet alpha granule lumen
0.34	GO:0005634	nucleus
0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.53

GO:0016491

sp|Q5ZMK5|JMJD6_CHICK
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6
Search

JMJD6

0.93	Arginine demethylase and lysine hydroxylase

0.61	GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine
0.61	GO:0070077	histone arginine demethylation
0.57	GO:0006909	phagocytosis
0.56	GO:0002040	sprouting angiogenesis
0.56	GO:0048024	regulation of mRNA splicing, via spliceosome
0.54	GO:0048821	erythrocyte development
0.54	GO:0033077	T cell differentiation in thymus
0.54	GO:0042116	macrophage activation
0.53	GO:0032259	methylation
0.53	GO:0030324	lung development

0.62	GO:0033749	histone demethylase activity (H4-R3 specific)
0.62	GO:0033746	histone demethylase activity (H3-R2 specific)
0.58	GO:0070815	peptidyl-lysine 5-dioxygenase activity
0.54	GO:0003727	single-stranded RNA binding
0.54	GO:0008168	methyltransferase activity
0.49	GO:0042802	identical protein binding
0.46	GO:0046983	protein dimerization activity
0.45	GO:0004872	receptor activity
0.45	GO:0005506	iron ion binding

0.51	GO:0005730	nucleolus
0.50	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol
0.43	GO:0030529	intracellular ribonucleoprotein complex
0.41	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.54

GO:0008168

sp|Q5ZMK7|UFM1_CHICK
Ubiquitin-fold modifier 1
Search

UFM1

0.90	Ubiquitin-fold modifier 1

0.86	GO:0071569	protein ufmylation
0.71	GO:0033146	regulation of intracellular estrogen receptor signaling pathway
0.69	GO:0034976	response to endoplasmic reticulum stress
0.44	GO:0043066	negative regulation of apoptotic process
0.39	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus
0.33	GO:0055114	oxidation-reduction process

0.38	GO:0005515	protein binding
0.35	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.61	GO:0005634	nucleus
0.57	GO:0005783	endoplasmic reticulum
0.42	GO:0070062	extracellular exosome

0.35

EC:1.2.1

GO:0016620

tr|Q5ZMK9|Q5ZMK9_CHICK
Uncharacterized protein
Search

ADK

0.63	Adenosine kinase a

0.75	GO:0006166	purine ribonucleoside salvage
0.74	GO:0006167	AMP biosynthetic process
0.57	GO:0006175	dATP biosynthetic process
0.53	GO:0016310	phosphorylation
0.49	GO:0046086	adenosine biosynthetic process
0.41	GO:0044262	cellular carbohydrate metabolic process
0.37	GO:0032261	purine nucleotide salvage
0.35	GO:0044342	type B pancreatic cell proliferation
0.35	GO:0010613	positive regulation of cardiac muscle hypertrophy
0.35	GO:0032922	circadian regulation of gene expression

0.84	GO:0004001	adenosine kinase activity
0.43	GO:0019200	carbohydrate kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046872	metal ion binding
0.34	GO:0003723	RNA binding

0.48	GO:0005829	cytosol
0.46	GO:0005654	nucleoplasm

0.84

EC:2.7.1.20

GO:0004001

sp|Q5ZML0|BRE_CHICK
BRCA1-A complex subunit BRE
Search

BABAM2

0.93	BRISC and BRCA1-A complex member 2

0.74	GO:0072425	signal transduction involved in G2 DNA damage checkpoint
0.71	GO:0045739	positive regulation of DNA repair
0.70	GO:0010212	response to ionizing radiation
0.64	GO:0006302	double-strand break repair
0.62	GO:0043066	negative regulation of apoptotic process
0.51	GO:0006915	apoptotic process
0.50	GO:0016569	covalent chromatin modification
0.47	GO:0051301	cell division
0.47	GO:0007049	cell cycle
0.38	GO:0070536	protein K63-linked deubiquitination

0.71	GO:0031593	polyubiquitin modification-dependent protein binding
0.65	GO:0005164	tumor necrosis factor receptor binding
0.38	GO:0000268	peroxisome targeting sequence binding

0.85	GO:0070552	BRISC complex
0.85	GO:0070531	BRCA1-A complex
0.63	GO:0000152	nuclear ubiquitin ligase complex
0.56	GO:0005829	cytosol
0.36	GO:0005654	nucleoplasm

sp|Q5ZML1|IMA5_CHICK
Importin subunit alpha-5
Search

KPNA1

0.60	Importin subunit alpha

0.78	GO:0006606	protein import into nucleus
0.41	GO:0060135	maternal process involved in female pregnancy
0.39	GO:0045944	positive regulation of transcription by RNA polymerase II
0.36	GO:0098926	postsynaptic signal transduction
0.35	GO:0006309	apoptotic DNA fragmentation
0.34	GO:0000018	regulation of DNA recombination
0.34	GO:0075733	intracellular transport of virus
0.33	GO:0044068	modulation by symbiont of host cellular process
0.33	GO:0019048	modulation by virus of host morphology or physiology

0.81	GO:0061608	nuclear import signal receptor activity
0.69	GO:0008565	protein transporter activity
0.48	GO:0008139	nuclear localization sequence binding
0.35	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.50	GO:0005829	cytosol
0.48	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.42	GO:0012505	endomembrane system
0.40	GO:0030425	dendrite
0.40	GO:0031975	envelope
0.40	GO:0043234	protein complex
0.33	GO:0044216	other organism cell
0.33	GO:0018995	host

sp|Q5ZML3|SRSF1_CHICK
Serine/arginine-rich splicing factor 1
Search

SRSF1

0.94	Serine and arginine rich splicing factor 1

0.53	GO:0000395	mRNA 5'-splice site recognition
0.52	GO:0000380	alternative mRNA splicing, via spliceosome
0.51	GO:0060048	cardiac muscle contraction
0.48	GO:0001701	in utero embryonic development
0.38	GO:0097421	liver regeneration
0.38	GO:0033120	positive regulation of RNA splicing
0.38	GO:0048709	oligodendrocyte differentiation
0.37	GO:0051028	mRNA transport
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus

0.59	GO:0003723	RNA binding
0.54	GO:0050733	RS domain binding
0.54	GO:0044547	DNA topoisomerase binding
0.39	GO:0043422	protein kinase B binding

0.52	GO:0016607	nuclear speck
0.52	GO:0035145	exon-exon junction complex
0.50	GO:0071013	catalytic step 2 spliceosome
0.36	GO:0070062	extracellular exosome
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q5ZML4|CHRD1_CHICK
Cysteine and histidine-rich domain-containing protein 1
Search

CHORDC1

0.79	Cysteine and histidine-rich domain-containing protein 1

0.76	GO:1900034	regulation of cellular response to heat
0.73	GO:2000299	negative regulation of Rho-dependent protein serine/threonine kinase activity
0.73	GO:0010824	regulation of centrosome duplication
0.68	GO:0061077	chaperone-mediated protein folding

0.82	GO:0051879	Hsp90 protein binding
0.59	GO:0043531	ADP binding
0.51	GO:0008270	zinc ion binding
0.48	GO:0005509	calcium ion binding
0.46	GO:0005524	ATP binding

sp|Q5ZML5|LSM12_CHICK
Protein LSM12 homolog
Search

0.46	GO:0070932	histone H3 deacetylation
0.45	GO:0040029	regulation of gene expression, epigenetic
0.40	GO:0006749	glutathione metabolic process
0.39	GO:0006351	transcription, DNA-templated
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.46	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
0.41	GO:0004364	glutathione transferase activity

0.40	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.46

GO:0032041

sp|Q5ZML6|F210A_CHICK
Protein FAM210A
Search

0.48	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

sp|Q5ZML7|LAP4A_CHICK
Lysosomal-associated transmembrane protein 4A
Search

LAPTM4A

0.96	Lysosomal-associated protein transmembrane 4 alpha

0.35	GO:1905671	regulation of lysosome organization
0.35	GO:1905166	negative regulation of lysosomal protein catabolic process
0.35	GO:0097213	regulation of lysosomal membrane permeability
0.35	GO:0032911	negative regulation of transforming growth factor beta1 production
0.35	GO:0007032	endosome organization
0.34	GO:0032509	endosome transport via multivesicular body sorting pathway

0.35	GO:0097001	ceramide binding
0.34	GO:1902936	phosphatidylinositol bisphosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding

0.55	GO:0031902	late endosome membrane
0.55	GO:0005765	lysosomal membrane
0.49	GO:0005794	Golgi apparatus
0.35	GO:0097487	multivesicular body, internal vesicle
0.34	GO:0005769	early endosome
0.33	GO:0042995	cell projection
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q5ZML9|SETD3_CHICK
Histone-lysine N-methyltransferase setd3
Search

SETD3

0.53	Histone-lysine N-methyltransferase

0.85	GO:0010452	histone H3-K36 methylation
0.85	GO:0018027	peptidyl-lysine dimethylation
0.85	GO:0018026	peptidyl-lysine monomethylation
0.85	GO:0018023	peptidyl-lysine trimethylation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0051568	histone H3-K4 methylation
0.55	GO:0051149	positive regulation of muscle cell differentiation
0.53	GO:1902680	positive regulation of RNA biosynthetic process
0.52	GO:0010628	positive regulation of gene expression
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.85	GO:0046975	histone methyltransferase activity (H3-K36 specific)
0.79	GO:0003713	transcription coactivator activity
0.57	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.55	GO:0001102	RNA polymerase II activating transcription factor binding
0.33	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.53	GO:0000790	nuclear chromatin
0.34	GO:0005654	nucleoplasm

sp|Q5ZMM1|NO66_CHICK
Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66
Search

RIOX1

0.93	MYC induced nuclear antigen

0.66	GO:0070544	histone H3-K36 demethylation
0.65	GO:0034720	histone H3-K4 demethylation
0.60	GO:0030961	peptidyl-arginine hydroxylation
0.59	GO:0045668	negative regulation of osteoblast differentiation
0.56	GO:0032259	methylation
0.55	GO:0045892	negative regulation of transcription, DNA-templated
0.53	GO:0006338	chromatin remodeling
0.42	GO:0055114	oxidation-reduction process
0.39	GO:0006351	transcription, DNA-templated
0.34	GO:0042254	ribosome biogenesis

0.66	GO:0032453	histone demethylase activity (H3-K4 specific)
0.66	GO:0051864	histone demethylase activity (H3-K36 specific)
0.56	GO:0008168	methyltransferase activity
0.47	GO:0005506	iron ion binding
0.35	GO:0005515	protein binding

0.53	GO:0005730	nucleolus
0.41	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.66

EC:1.14.11.27

GO:0051864

sp|Q5ZMM3|RHG15_CHICK
Rho GTPase-activating protein 15
Search

ARHGAP15

0.97	LOW QUALITY PROTEIN: rho GTPase-activating protein 15

0.68	GO:0043547	positive regulation of GTPase activity
0.59	GO:0007165	signal transduction
0.50	GO:0008360	regulation of cell shape
0.36	GO:0051056	regulation of small GTPase mediated signal transduction
0.36	GO:0006911	phagocytosis, engulfment
0.36	GO:0002011	morphogenesis of an epithelial sheet
0.35	GO:1902532	negative regulation of intracellular signal transduction
0.35	GO:0007015	actin filament organization

0.68	GO:0005096	GTPase activator activity
0.42	GO:0005543	phospholipid binding

0.36	GO:0001891	phagocytic cup
0.34	GO:0005737	cytoplasm

sp|Q5ZMM5|ZN706_CHICK
Zinc finger protein 706
Search

ZNF706

0.97	Zinc finger protein 706

0.85	GO:1902455	negative regulation of stem cell population maintenance
0.69	GO:0045892	negative regulation of transcription, DNA-templated
0.42	GO:0006417	regulation of translation

0.39	GO:0019904	protein domain specific binding
0.37	GO:0046872	metal ion binding
0.33	GO:0003676	nucleic acid binding

0.59	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|Q5ZMM7|Q5ZMM7_CHICK
Uncharacterized protein
Search

ELK3

0.97	ETS domain-containing protein Elk-3

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0001525	angiogenesis
0.56	GO:0010468	regulation of gene expression
0.56	GO:0042060	wound healing
0.54	GO:0006366	transcription by RNA polymerase II
0.53	GO:1902680	positive regulation of RNA biosynthetic process
0.52	GO:1902679	negative regulation of RNA biosynthetic process
0.45	GO:0030154	cell differentiation
0.33	GO:0007165	signal transduction

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.57	GO:0003714	transcription corepressor activity
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.49	GO:0031974	membrane-enclosed lumen
0.46	GO:0005739	mitochondrion
0.44	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|Q5ZMM8|Q5ZMM8_CHICK
Uncharacterized protein
Search

CTBP1

0.86	C-terminal-binding protein 2

0.53	GO:0055114	oxidation-reduction process
0.50	GO:0050872	white fat cell differentiation
0.50	GO:1903756	regulation of transcription from RNA polymerase II promoter by histone modification
0.49	GO:0090241	negative regulation of histone H4 acetylation
0.49	GO:0031065	positive regulation of histone deacetylation
0.46	GO:1903507	negative regulation of nucleic acid-templated transcription
0.44	GO:0048384	retinoic acid receptor signaling pathway
0.44	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.43	GO:0051726	regulation of cell cycle
0.43	GO:0010629	negative regulation of gene expression

0.68	GO:0051287	NAD binding
0.66	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.49	GO:0003714	transcription corepressor activity
0.47	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.47	GO:0070491	repressing transcription factor binding
0.45	GO:0001104	RNA polymerase II transcription cofactor activity
0.45	GO:0019904	protein domain specific binding
0.42	GO:0042803	protein homodimerization activity
0.40	GO:0003700	DNA binding transcription factor activity
0.35	GO:0042974	retinoic acid receptor binding

0.47	GO:0017053	transcriptional repressor complex
0.44	GO:0005667	transcription factor complex
0.42	GO:0005654	nucleoplasm
0.41	GO:0005829	cytosol
0.35	GO:0045202	synapse
0.34	GO:0097458	neuron part

0.66

EC:1.1.1

GO:0016616

tr|Q5ZMM9|Q5ZMM9_CHICK
Uncharacterized protein
Search

CACUL1

0.97	CDK2-associated and cullin domain-containing protein 1

0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.52	GO:0000082	G1/S transition of mitotic cell cycle
0.51	GO:0008284	positive regulation of cell proliferation
0.50	GO:0045860	positive regulation of protein kinase activity
0.42	GO:0016567	protein ubiquitination
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0043547	positive regulation of GTPase activity

0.78	GO:0031625	ubiquitin protein ligase binding
0.50	GO:0019901	protein kinase binding
0.43	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0004983	neuropeptide Y receptor activity
0.34	GO:0001965	G-protein alpha-subunit binding
0.34	GO:0005092	GDP-dissociation inhibitor activity
0.33	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0005096	GTPase activator activity

0.43	GO:0031461	cullin-RING ubiquitin ligase complex
0.33	GO:0000152	nuclear ubiquitin ligase complex
0.32	GO:0005886	plasma membrane
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q5ZMN0|AN32B_CHICK
Acidic leucine-rich nuclear phosphoprotein 32 family member B
Search

0.87	Acidic leucine-rich nuclear phosphoprotein 32 family member B

0.66	GO:0043486	histone exchange
0.64	GO:0006334	nucleosome assembly
0.62	GO:0042981	regulation of apoptotic process
0.58	GO:0006913	nucleocytoplasmic transport
0.44	GO:2000116	regulation of cysteine-type endopeptidase activity
0.41	GO:0046827	positive regulation of protein export from nucleus
0.41	GO:0010950	positive regulation of endopeptidase activity
0.40	GO:0050793	regulation of developmental process
0.40	GO:0048523	negative regulation of cellular process
0.40	GO:0043068	positive regulation of programmed cell death

0.65	GO:0042393	histone binding
0.46	GO:0032403	protein complex binding
0.39	GO:0070063	RNA polymerase binding

0.67	GO:0016363	nuclear matrix
0.47	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0031012	extracellular matrix
0.44	GO:0005783	endoplasmic reticulum
0.39	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

tr|Q5ZMN1|Q5ZMN1_CHICK
Uncharacterized protein
Search

G3BP1

0.96	Ras GTPase-activating protein-binding protein 1

0.52	GO:0034063	stress granule assembly
0.50	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.35	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.34	GO:0007265	Ras protein signal transduction
0.33	GO:0032392	DNA geometric change

0.59	GO:0003723	RNA binding
0.36	GO:0004386	helicase activity
0.36	GO:0004519	endonuclease activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0003677	DNA binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008186	RNA-dependent ATPase activity
0.34	GO:0005515	protein binding
0.33	GO:0008094	DNA-dependent ATPase activity

0.49	GO:0010494	cytoplasmic stress granule
0.47	GO:0005829	cytosol
0.36	GO:0005925	focal adhesion
0.35	GO:0005634	nucleus
0.34	GO:0005886	plasma membrane

sp|Q5ZMN2|MCM3_CHICK
DNA replication licensing factor MCM3
Search

MCM3

0.52	Zygotic DNA replication licensing factor mcm3

0.75	GO:0006270	DNA replication initiation
0.53	GO:0007049	cell cycle
0.42	GO:0030174	regulation of DNA-dependent DNA replication initiation

0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0004386	helicase activity
0.46	GO:0003682	chromatin binding
0.40	GO:0005515	protein binding

0.80	GO:0042555	MCM complex
0.51	GO:0005634	nucleus
0.49	GO:0005813	centrosome
0.46	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0031974	membrane-enclosed lumen
0.41	GO:0000781	chromosome, telomeric region
0.40	GO:0000428	DNA-directed RNA polymerase complex
0.40	GO:0030894	replisome
0.30	GO:0016020	membrane

sp|Q5ZMN3|PHB2_CHICK
Prohibitin-2
Search

PHB2

0.85	Prohibitin-2

0.56	GO:0033600	negative regulation of mammary gland epithelial cell proliferation
0.56	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis
0.55	GO:0031536	positive regulation of exit from mitosis
0.55	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway
0.54	GO:0000060	protein import into nucleus, translocation
0.54	GO:1902808	positive regulation of cell cycle G1/S phase transition
0.53	GO:0060744	mammary gland branching involved in thelarche
0.52	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.52	GO:0043433	negative regulation of DNA binding transcription factor activity
0.52	GO:0051091	positive regulation of DNA binding transcription factor activity

0.53	GO:0047485	protein N-terminus binding
0.52	GO:0008022	protein C-terminus binding
0.47	GO:0033218	amide binding
0.35	GO:0030331	estrogen receptor binding

0.54	GO:0016363	nuclear matrix
0.50	GO:0005741	mitochondrial outer membrane
0.49	GO:0009986	cell surface
0.44	GO:0005743	mitochondrial inner membrane
0.43	GO:0043234	protein complex
0.40	GO:0071944	cell periphery
0.38	GO:0030424	axon
0.36	GO:0031982	vesicle
0.36	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space

tr|Q5ZMN4|Q5ZMN4_CHICK
Uncharacterized protein
Search

UBR7

0.88	Ubiquitin protein ligase E3 component n-recognin 7

0.37

GO:0016567

protein ubiquitination

0.59	GO:0016874	ligase activity
0.57	GO:0008270	zinc ion binding
0.34	GO:0016740	transferase activity

0.30

GO:0044425

membrane part

0.59

GO:0016874

tr|Q5ZMP2|Q5ZMP2_CHICK
Uncharacterized protein
Search

STX7

0.93	Syntaxin 7 (Predicted)

0.69	GO:0016192	vesicle-mediated transport
0.68	GO:0006886	intracellular protein transport
0.68	GO:0061025	membrane fusion
0.61	GO:1902685	positive regulation of receptor localization to synapse
0.59	GO:0001916	positive regulation of T cell mediated cytotoxicity
0.57	GO:1903076	regulation of protein localization to plasma membrane
0.53	GO:0051640	organelle localization
0.50	GO:0070925	organelle assembly
0.47	GO:0065009	regulation of molecular function
0.47	GO:0048284	organelle fusion

0.80	GO:0005484	SNAP receptor activity
0.60	GO:0019869	chloride channel inhibitor activity
0.56	GO:0000149	SNARE binding
0.34	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.34	GO:0032403	protein complex binding
0.33	GO:0005507	copper ion binding

0.59	GO:0070820	tertiary granule
0.58	GO:0005766	primary lysosome
0.57	GO:0001772	immunological synapse
0.55	GO:0055037	recycling endosome
0.55	GO:0030139	endocytic vesicle
0.55	GO:0005769	early endosome
0.54	GO:0005770	late endosome
0.54	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0031201	SNARE complex
0.39	GO:0010008	endosome membrane

0.34

EC:1.14.17

GO:0016715

sp|Q5ZMP3|T184C_CHICK
Transmembrane protein 184C
Search

TMEM184C

0.52	Transmembrane protein 34

0.39

GO:0005215

transporter activity

0.30

GO:0044425

membrane part

tr|Q5ZMP4|Q5ZMP4_CHICK
Uncharacterized protein
Search

USP45

0.39	Ubiquitinyl hydrolase 1

0.75	GO:0016579	protein deubiquitination
0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.48	GO:0051289	protein homotetramerization
0.47	GO:0016570	histone modification
0.46	GO:0006974	cellular response to DNA damage stimulus
0.46	GO:0051726	regulation of cell cycle
0.45	GO:0140014	mitotic nuclear division
0.44	GO:0045893	positive regulation of transcription, DNA-templated
0.43	GO:0006259	DNA metabolic process
0.42	GO:0051301	cell division

0.76	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.63	GO:0008270	zinc ion binding
0.46	GO:0043130	ubiquitin binding
0.46	GO:0042393	histone binding
0.46	GO:0003713	transcription coactivator activity
0.45	GO:0004197	cysteine-type endopeptidase activity

0.47	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

0.76

EC:3.4.19.12

GO:0036459

sp|Q5ZMP6|AP2M1_CHICK
AP-2 complex subunit mu
Search

AP2M1

0.86	AP-2 complex subunit mu-B

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.41	GO:0098657	import into cell
0.39	GO:0097494	regulation of vesicle size
0.39	GO:1900244	positive regulation of synaptic vesicle endocytosis
0.38	GO:1903077	negative regulation of protein localization to plasma membrane
0.38	GO:0002092	positive regulation of receptor internalization
0.38	GO:0016050	vesicle organization
0.38	GO:0036465	synaptic vesicle recycling
0.37	GO:0097480	establishment of synaptic vesicle localization

0.71	GO:0008289	lipid binding
0.51	GO:0097718	disordered domain specific binding
0.39	GO:0050750	low-density lipoprotein particle receptor binding
0.38	GO:0005048	signal sequence binding
0.37	GO:0044325	ion channel binding
0.35	GO:0035615	clathrin adaptor activity
0.35	GO:0004222	metalloendopeptidase activity
0.34	GO:0008270	zinc ion binding
0.32	GO:0005215	transporter activity

0.79	GO:0030131	clathrin adaptor complex
0.43	GO:0005905	clathrin-coated pit
0.41	GO:0005739	mitochondrion
0.41	GO:0005886	plasma membrane
0.39	GO:0030128	clathrin coat of endocytic vesicle
0.38	GO:0043195	terminal bouton
0.36	GO:0044421	extracellular region part
0.35	GO:0036020	endolysosome membrane
0.34	GO:0030141	secretory granule
0.33	GO:0005829	cytosol

0.35

GO:0004222

sp|Q5ZMP7|AP3M1_CHICK
AP-3 complex subunit mu-1
Search

AP3M1

0.91	LOW QUALITY PROTEIN: AP-3 complex subunit mu-1

0.68	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.65	GO:0008089	anterograde axonal transport
0.64	GO:0047496	vesicle transport along microtubule
0.62	GO:0097480	establishment of synaptic vesicle localization
0.35	GO:0061462	protein localization to lysosome
0.35	GO:0007041	lysosomal transport
0.35	GO:0072666	establishment of protein localization to vacuole

0.54

GO:0017137

Rab GTPase binding

0.78	GO:0030131	clathrin adaptor complex
0.64	GO:1904115	axon cytoplasm
0.40	GO:0030659	cytoplasmic vesicle membrane
0.39	GO:0005794	Golgi apparatus
0.36	GO:0005765	lysosomal membrane
0.34	GO:0030136	clathrin-coated vesicle

sp|Q5ZMQ0|ARMC1_CHICK
Armadillo repeat-containing protein 1
Search

ARMC1

0.96	Armadillo repeat-containing protein 1

0.65

GO:0030001

metal ion transport

0.53	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.42	GO:0005739	mitochondrion
0.41	GO:0005634	nucleus

sp|Q5ZMQ2|ACTG_CHICK
Actin, cytoplasmic 2
Search

ACTB

0.63	Actin cytoplasmic 1

0.53	GO:0098974	postsynaptic actin cytoskeleton organization
0.52	GO:0072749	cellular response to cytochalasin B
0.49	GO:0032091	negative regulation of protein binding
0.46	GO:0045214	sarcomere organization
0.46	GO:0071346	cellular response to interferon-gamma
0.44	GO:0048870	cell motility
0.39	GO:0070527	platelet aggregation
0.39	GO:0001895	retina homeostasis
0.37	GO:0021762	substantia nigra development
0.37	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis

0.53	GO:0098973	structural constituent of postsynaptic actin cytoskeleton
0.51	GO:0030554	adenyl nucleotide binding
0.51	GO:0030957	Tat protein binding
0.51	GO:0050998	nitric-oxide synthase binding
0.51	GO:0097367	carbohydrate derivative binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0008144	drug binding
0.50	GO:0042802	identical protein binding
0.49	GO:0019894	kinesin binding
0.49	GO:0005522	profilin binding

0.76	GO:0097433	dense body
0.70	GO:0005925	focal adhesion
0.61	GO:0005856	cytoskeleton
0.53	GO:0043209	myelin sheath
0.50	GO:0005886	plasma membrane
0.47	GO:0035267	NuA4 histone acetyltransferase complex
0.47	GO:0036464	cytoplasmic ribonucleoprotein granule
0.47	GO:0070062	extracellular exosome
0.46	GO:0044448	cell cortex part
0.45	GO:0005829	cytosol

tr|Q5ZMQ3|Q5ZMQ3_CHICK
Signal peptidase complex catalytic subunit SEC11
Search

SEC11A

0.72	Signal peptidase complex catalytic subunit SEC11

0.80	GO:0006465	signal peptide processing
0.34	GO:0018108	peptidyl-tyrosine phosphorylation

0.67	GO:0017171	serine hydrolase activity
0.62	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.34	GO:0004713	protein tyrosine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.82	GO:0005787	signal peptidase complex
0.36	GO:0031090	organelle membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.34

GO:0004713

tr|Q5ZMQ7|Q5ZMQ7_CHICK
Uncharacterized protein
Search

SH3KBP1

0.93	SH3 domain containing kinase binding protein 1

0.55	GO:0016310	phosphorylation
0.50	GO:0016477	cell migration
0.47	GO:0007010	cytoskeleton organization
0.47	GO:0008360	regulation of cell shape
0.41	GO:0072554	blood vessel lumenization
0.37	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.36	GO:0007411	axon guidance
0.36	GO:0006915	apoptotic process
0.36	GO:0007267	cell-cell signaling
0.35	GO:0006897	endocytosis

0.57	GO:0016301	kinase activity
0.37	GO:0005515	protein binding
0.31	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.31	GO:0140096	catalytic activity, acting on a protein
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0030139	endocytic vesicle
0.49	GO:0005911	cell-cell junction
0.36	GO:0005925	focal adhesion
0.36	GO:0043005	neuron projection
0.36	GO:0030659	cytoplasmic vesicle membrane
0.36	GO:0045202	synapse
0.35	GO:0005856	cytoskeleton
0.35	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane

0.31

GO:0016773

sp|Q5ZMQ9|PEX5_CHICK
Peroxisomal targeting signal 1 receptor
Search

PEX5

0.91	Peroxisomal targeting signal 1 receptor

0.79	GO:0016558	protein import into peroxisome matrix
0.78	GO:0021895	cerebral cortex neuron differentiation
0.77	GO:0021795	cerebral cortex cell migration
0.76	GO:0040018	positive regulation of multicellular organism growth
0.75	GO:0050905	neuromuscular process
0.74	GO:0000038	very long-chain fatty acid metabolic process
0.74	GO:0001764	neuron migration
0.73	GO:0007029	endoplasmic reticulum organization
0.71	GO:0007006	mitochondrial membrane organization
0.69	GO:0006635	fatty acid beta-oxidation

0.71	GO:0005052	peroxisome matrix targeting signal-1 binding
0.49	GO:0008022	protein C-terminus binding
0.46	GO:0047485	protein N-terminus binding
0.43	GO:0031267	small GTPase binding

0.68	GO:0005829	cytosol
0.67	GO:0005794	Golgi apparatus
0.61	GO:0031903	microbody membrane
0.61	GO:0044439	peroxisomal part
0.55	GO:0005739	mitochondrion
0.52	GO:0031907	microbody lumen
0.38	GO:0043234	protein complex

sp|Q5ZMR3|PCMD1_CHICK
Protein-L-isoaspartate O-methyltransferase domain-containing protein 1
Search

PCMTD1

0.97	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1

0.73	GO:0008213	protein alkylation
0.67	GO:0043414	macromolecule methylation

0.79	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity
0.32	GO:0016887	ATPase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:2.1.1.77

GO:0004719

tr|Q5ZMR4|Q5ZMR4_CHICK
Uncharacterized protein
Search

SRSF10

0.97	Serine and arginine rich splicing factor 10

0.79	GO:0043484	regulation of RNA splicing
0.54	GO:0006376	mRNA splice site selection
0.52	GO:0050684	regulation of mRNA processing
0.50	GO:0016482	cytosolic transport
0.49	GO:1903312	negative regulation of mRNA metabolic process
0.46	GO:0010629	negative regulation of gene expression
0.41	GO:0045292	mRNA cis splicing, via spliceosome
0.37	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.37	GO:0000244	spliceosomal tri-snRNP complex assembly
0.37	GO:0051028	mRNA transport

0.57	GO:0003723	RNA binding
0.38	GO:0050733	RS domain binding
0.37	GO:0051082	unfolded protein binding

0.50	GO:0016607	nuclear speck
0.45	GO:0005829	cytosol

sp|Q5ZMR9|XPO4_CHICK
Exportin-4
Search

XPO4

0.91	Exportin-4

0.81	GO:0046827	positive regulation of protein export from nucleus
0.65	GO:0006611	protein export from nucleus

0.66	GO:0005049	nuclear export signal receptor activity
0.61	GO:0008536	Ran GTPase binding

0.67	GO:0005654	nucleoplasm
0.65	GO:0005829	cytosol
0.60	GO:0005643	nuclear pore

sp|Q5ZMS1|TAF8_CHICK
Transcription initiation factor TFIID subunit 8
Search

TAF8

0.94	Transcription initiation factor TFIID subunit 8

0.59	GO:0006413	translational initiation
0.54	GO:0051457	maintenance of protein location in nucleus
0.53	GO:0045598	regulation of fat cell differentiation
0.52	GO:0001833	inner cell mass cell proliferation
0.48	GO:0045893	positive regulation of transcription, DNA-templated
0.39	GO:0030154	cell differentiation
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:0006030	chitin metabolic process
0.35	GO:0005975	carbohydrate metabolic process
0.35	GO:0016073	snRNA metabolic process

0.69	GO:0046982	protein heterodimerization activity
0.59	GO:0003743	translation initiation factor activity
0.37	GO:0008061	chitin binding
0.35	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.73	GO:0005669	transcription factor TFIID complex
0.51	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.35

GO:0004553

sp|Q5ZMS2|PA1B2_CHICK
Platelet-activating factor acetylhydrolase IB subunit beta
Search

PAFAH1B2

0.84	Platelet-activating factor acetylhydrolase IB subunit beta

0.56	GO:0007283	spermatogenesis
0.54	GO:0016239	positive regulation of macroautophagy
0.49	GO:0007420	brain development
0.41	GO:0016042	lipid catabolic process
0.36	GO:0043312	neutrophil degranulation

0.55	GO:0047179	platelet-activating factor acetyltransferase activity
0.47	GO:0016787	hydrolase activity
0.45	GO:0042802	identical protein binding
0.38	GO:0046982	protein heterodimerization activity

0.53	GO:0001650	fibrillar center
0.47	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.38	GO:0070062	extracellular exosome
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0034774	secretory granule lumen

0.55

EC:2.3.1.149

GO:0047179

sp|Q5ZMS3|IF2G_CHICK
Eukaryotic translation initiation factor 2 subunit 3
Search

EIF2S3

0.78	Eukaryotic translation initiation factor 2 subunit gamma X

0.62	GO:0006413	translational initiation
0.32	GO:0055085	transmembrane transport

0.67	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.63	GO:0003743	translation initiation factor activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0045296	cadherin binding

0.44	GO:0005850	eukaryotic translation initiation factor 2 complex
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q5ZMS4|NCOA7_CHICK
Nuclear receptor coactivator 7
Search

NCOA7

0.94	Nuclear receptor coactivator 7

0.86	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation
0.85	GO:1903204	negative regulation of oxidative stress-induced neuron death
0.72	GO:0045944	positive regulation of transcription by RNA polymerase II
0.40	GO:0006351	transcription, DNA-templated
0.33	GO:0032259	methylation

0.82	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.81	GO:0035257	nuclear hormone receptor binding
0.33	GO:0008168	methyltransferase activity
0.33	GO:0003676	nucleic acid binding

0.45	GO:0005622	intracellular
0.39	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.33

GO:0008168

sp|Q5ZMS6|TDRD3_CHICK
Tudor domain-containing protein 3
Search

TDRD3

0.94	LOW QUALITY PROTEIN: tudor domain-containing protein 3

0.64	GO:0006397	mRNA processing
0.47	GO:2001141	regulation of RNA biosynthetic process
0.43	GO:0016569	covalent chromatin modification

0.65	GO:0035064	methylated histone binding
0.61	GO:0003713	transcription coactivator activity
0.60	GO:0003682	chromatin binding
0.55	GO:0003723	RNA binding

0.66	GO:0035145	exon-exon junction complex
0.55	GO:0005794	Golgi apparatus
0.54	GO:0005654	nucleoplasm
0.53	GO:0005829	cytosol

sp|Q5ZMT0|1433E_CHICK
14-3-3 protein epsilon
Search

YWHAE

0.91	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon

0.55	GO:1905912	regulation of calcium ion export across plasma membrane
0.54	GO:1902309	negative regulation of peptidyl-serine dephosphorylation
0.52	GO:0046827	positive regulation of protein export from nucleus
0.52	GO:0060306	regulation of membrane repolarization
0.52	GO:1901020	negative regulation of calcium ion transmembrane transporter activity
0.51	GO:1901016	regulation of potassium ion transmembrane transporter activity
0.50	GO:0034605	cellular response to heat
0.50	GO:0051480	regulation of cytosolic calcium ion concentration
0.50	GO:0021766	hippocampus development
0.49	GO:0000165	MAPK cascade

0.75	GO:0019904	protein domain specific binding
0.53	GO:0050815	phosphoserine residue binding
0.52	GO:0015459	potassium channel regulator activity
0.52	GO:0097110	scaffold protein binding
0.51	GO:0005246	calcium channel regulator activity
0.51	GO:0044325	ion channel binding
0.51	GO:0042826	histone deacetylase binding
0.50	GO:0045296	cadherin binding
0.49	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0046982	protein heterodimerization activity

0.42	GO:0005634	nucleus
0.42	GO:0090724	central region of growth cone
0.41	GO:0042470	melanosome
0.41	GO:0005739	mitochondrion
0.40	GO:0005886	plasma membrane
0.40	GO:0005871	kinesin complex
0.39	GO:0030424	axon
0.37	GO:0005829	cytosol
0.37	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome

tr|Q5ZMT4|Q5ZMT4_CHICK
Uncharacterized protein
Search

TMED5

0.96	Transmembrane emp24 protein transport domain containing 5

0.58	GO:0090161	Golgi ribbon formation
0.37	GO:0015031	protein transport

0.33

GO:0005515

protein binding

0.57	GO:0070971	endoplasmic reticulum exit site
0.56	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.54	GO:0005801	cis-Golgi network
0.39	GO:0005794	Golgi apparatus
0.38	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0098588	bounding membrane of organelle
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q5ZMT7|ADCK1_CHICK
Uncharacterized aarF domain-containing protein kinase 1
Search

ADCK1

0.96	AarF domain-containing protein kinase 1

0.58	GO:0006468	protein phosphorylation
0.33	GO:0031571	mitotic G1 DNA damage checkpoint
0.33	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

0.58	GO:0004672	protein kinase activity
0.51	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0030332	cyclin binding

0.41	GO:0005739	mitochondrion
0.37	GO:0005576	extracellular region
0.33	GO:0019005	SCF ubiquitin ligase complex
0.30	GO:0016020	membrane

sp|Q5ZMT9|INSI1_CHICK
Insulin-induced gene 1 protein
Search

INSIG1

0.94	Insulin-induced gene protein (Fragment)

0.83	GO:0008203	cholesterol metabolic process
0.59	GO:0060363	cranial suture morphogenesis
0.58	GO:0042474	middle ear morphogenesis
0.58	GO:0010894	negative regulation of steroid biosynthetic process
0.58	GO:0006991	response to sterol depletion
0.57	GO:0006984	ER-nucleus signaling pathway
0.56	GO:0060021	palate development
0.56	GO:0045717	negative regulation of fatty acid biosynthetic process
0.56	GO:0042472	inner ear morphogenesis
0.55	GO:0036316	SREBP-SCAP complex retention in endoplasmic reticulum

0.37

GO:0008134

transcription factor binding

0.65	GO:0005789	endoplasmic reticulum membrane
0.45	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

sp|Q5ZMU0|RT07_CHICK
28S ribosomal protein S7, mitochondrial
Search

MRPS7

0.92	Mitochondrial ribosomal protein S7

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.47	GO:0000028	ribosomal small subunit assembly
0.33	GO:0043624	cellular protein complex disassembly

0.45	GO:0003735	structural constituent of ribosome
0.44	GO:0019843	rRNA binding
0.44	GO:0003729	mRNA binding
0.40	GO:0000049	tRNA binding
0.32	GO:0016787	hydrolase activity

0.54	GO:0005840	ribosome
0.50	GO:0005759	mitochondrial matrix
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane
0.32	GO:0044445	cytosolic part
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

sp|Q5ZMU6|PP4R2_CHICK
Serine/threonine-protein phosphatase 4 regulatory subunit 2
Search

PPP4R2

0.95	Serine/threonine-protein phosphatase 4 regulatory subunit 2

0.79	GO:0043666	regulation of phosphoprotein phosphatase activity
0.55	GO:0010569	regulation of double-strand break repair via homologous recombination
0.37	GO:0002244	hematopoietic progenitor cell differentiation
0.36	GO:0008380	RNA splicing
0.36	GO:0006397	mRNA processing
0.33	GO:0006464	cellular protein modification process

0.80	GO:0019888	protein phosphatase regulator activity
0.52	GO:0030674	protein binding, bridging
0.34	GO:0016757	transferase activity, transferring glycosyl groups

0.85	GO:0030289	protein phosphatase 4 complex
0.47	GO:0005654	nucleoplasm
0.37	GO:0005815	microtubule organizing center
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016757

tr|Q5ZMU7|Q5ZMU7_CHICK
Protein-S-isoprenylcysteine O-methyltransferase
Search

ICMT

0.62	Protein-S-isoprenylcysteine O-methyltransferase

0.82	GO:0006481	C-terminal protein methylation
0.37	GO:0007186	G-protein coupled receptor signaling pathway
0.36	GO:0035264	multicellular organism growth
0.36	GO:0001889	liver development
0.36	GO:0001701	in utero embryonic development
0.36	GO:0008284	positive regulation of cell proliferation
0.35	GO:0046578	regulation of Ras protein signal transduction
0.35	GO:0008104	protein localization
0.34	GO:0046499	S-adenosylmethioninamine metabolic process
0.34	GO:0046498	S-adenosylhomocysteine metabolic process

0.83	GO:0004671	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
0.38	GO:0004930	G-protein coupled receptor activity
0.37	GO:0008140	cAMP response element binding protein binding
0.32	GO:0003676	nucleic acid binding

0.71	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.83	EC:2.1.1.100	GO:0004671
0.83	KEGG:R04496	GO:0004671

tr|Q5ZMV0|Q5ZMV0_CHICK
Uncharacterized protein
Search

0.70	Hematopoietic cell-specific Lyn substrate 1

0.83	GO:0030041	actin filament polymerization
0.49	GO:0030854	positive regulation of granulocyte differentiation
0.48	GO:0043066	negative regulation of apoptotic process
0.48	GO:0030833	regulation of actin filament polymerization
0.47	GO:0042993	positive regulation of transcription factor import into nucleus
0.47	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.47	GO:2000106	regulation of leukocyte apoptotic process
0.47	GO:0051897	positive regulation of protein kinase B signaling
0.47	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.46	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation

0.70	GO:0003779	actin binding
0.46	GO:0001085	RNA polymerase II transcription factor binding
0.45	GO:0019901	protein kinase binding
0.43	GO:0005522	profilin binding
0.41	GO:0045296	cadherin binding
0.41	GO:0017124	SH3 domain binding
0.40	GO:0032403	protein complex binding
0.34	GO:0016491	oxidoreductase activity
0.32	GO:0043565	sequence-specific DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005829	cytosol
0.44	GO:0005667	transcription factor complex
0.42	GO:0002102	podosome
0.42	GO:1990023	mitotic spindle midzone
0.41	GO:0001726	ruffle
0.41	GO:0005884	actin filament
0.41	GO:0030027	lamellipodium
0.41	GO:0030863	cortical cytoskeleton
0.40	GO:0008076	voltage-gated potassium channel complex
0.40	GO:0043231	intracellular membrane-bounded organelle

0.34

GO:0016491

sp|Q5ZMV2|SAS6_CHICK
Spindle assembly abnormal protein 6 homolog
Search

SASS6

0.89	Spindle assembly abnormal protein 6

0.85	GO:0007099	centriole replication
0.40	GO:0040016	embryonic cleavage
0.38	GO:0007052	mitotic spindle organization
0.38	GO:0007283	spermatogenesis
0.38	GO:0000280	nuclear division
0.35	GO:0016579	protein deubiquitination
0.34	GO:0006511	ubiquitin-dependent protein catabolic process
0.32	GO:0006836	neurotransmitter transport
0.32	GO:0065009	regulation of molecular function
0.31	GO:0055085	transmembrane transport

0.36	GO:0005515	protein binding
0.35	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.32	GO:0005328	neurotransmitter:sodium symporter activity
0.32	GO:0098772	molecular function regulator

0.85	GO:0098536	deuterosome
0.83	GO:0005814	centriole
0.76	GO:0005813	centrosome
0.66	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:3.4.19.12

GO:0036459

sp|Q5ZMV3|NC2B_CHICK
Protein Dr1
Search

DR1

0.97	Down-regulator of transcription 1

0.54	GO:0043966	histone H3 acetylation
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.34	GO:1902679	negative regulation of RNA biosynthetic process
0.33	GO:0006897	endocytosis

0.74	GO:0046982	protein heterodimerization activity
0.53	GO:0017025	TBP-class protein binding
0.35	GO:0003714	transcription corepressor activity
0.34	GO:0003677	DNA binding

0.58	GO:0005634	nucleus
0.51	GO:0031248	protein acetyltransferase complex
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0043234	protein complex
0.42	GO:0044446	intracellular organelle part

tr|Q5ZMV5|Q5ZMV5_CHICK
Actin-related protein 2/3 complex subunit 5
Search

ARPC5

0.71	Actin-related protein 2/3 complex subunit 5

0.81	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.53	GO:0016477	cell migration
0.39	GO:0021769	orbitofrontal cortex development
0.39	GO:0051639	actin filament network formation
0.38	GO:0030011	maintenance of cell polarity
0.38	GO:0097581	lamellipodium organization
0.38	GO:0061842	microtubule organizing center localization
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0048013	ephrin receptor signaling pathway

0.53	GO:0051015	actin filament binding
0.49	GO:0005200	structural constituent of cytoskeleton

0.80	GO:0005885	Arp2/3 protein complex
0.52	GO:0030027	lamellipodium
0.38	GO:0005925	focal adhesion
0.38	GO:0070062	extracellular exosome
0.38	GO:0030426	growth cone
0.37	GO:0005737	cytoplasm
0.36	GO:0097708	intracellular vesicle
0.35	GO:0012505	endomembrane system
0.35	GO:0031983	vesicle lumen
0.33	GO:0070013	intracellular organelle lumen

sp|Q5ZMV7|WDR82_CHICK
WD repeat-containing protein 82
Search

WDR82

0.87	WD repeat-containing protein 82-B

0.55	GO:0051568	histone H3-K4 methylation
0.50	GO:0018023	peptidyl-lysine trimethylation
0.47	GO:0030837	negative regulation of actin filament polymerization

0.55	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.51	GO:0003682	chromatin binding
0.48	GO:0003779	actin binding

0.81	GO:0072357	PTW/PP1 phosphatase complex
0.78	GO:0048188	Set1C/COMPASS complex
0.50	GO:0000784	nuclear chromosome, telomeric region
0.47	GO:0005730	nucleolus
0.46	GO:0000785	chromatin
0.30	GO:0031224	intrinsic component of membrane

sp|Q5ZMV8|RPGP2_CHICK
Rap1 GTPase-activating protein 2
Search

RAP1GAP2

0.97	Rap1 GTPase-activating protein 2

0.75	GO:0051056	regulation of small GTPase mediated signal transduction
0.75	GO:0043547	positive regulation of GTPase activity
0.53	GO:0008361	regulation of cell size
0.51	GO:0010977	negative regulation of neuron projection development

0.76	GO:0005096	GTPase activator activity
0.33	GO:0005515	protein binding

0.52	GO:0031965	nuclear membrane
0.51	GO:0005813	centrosome
0.48	GO:0043005	neuron projection
0.47	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.34	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q5ZMV9|WDR24_CHICK
WD repeat-containing protein 24
Search

WDR24

0.94	WD repeat-containing protein 24

0.80	GO:0032008	positive regulation of TOR signaling
0.54	GO:0034198	cellular response to amino acid starvation
0.48	GO:0010506	regulation of autophagy
0.39	GO:0006914	autophagy
0.33	GO:0016573	histone acetylation
0.32	GO:0055085	transmembrane transport

0.33	GO:0004402	histone acetyltransferase activity
0.32	GO:0022857	transmembrane transporter activity

0.54	GO:0061700	GATOR2 complex
0.52	GO:0005765	lysosomal membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004402

sp|Q5ZMW0|AGO4_CHICK
Protein argonaute-4
Search

0.86	Eukaryotic translation initiation factor 2C 4 (Fragment)

0.76	GO:0031047	gene silencing by RNA
0.72	GO:0006413	translational initiation

0.73

GO:0003743

translation initiation factor activity

sp|Q5ZMW3|API5_CHICK
Apoptosis inhibitor 5
Search

API5

0.95	Apoptosis inhibitor 5

0.84	GO:2000270	negative regulation of fibroblast apoptotic process
0.52	GO:0006915	apoptotic process

0.85	GO:0017134	fibroblast growth factor binding
0.36	GO:0003723	RNA binding

0.77	GO:0016607	nuclear speck
0.70	GO:0005681	spliceosomal complex
0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|Q5ZMW4|Q5ZMW4_CHICK
Uncharacterized protein
Search

OSTM1

0.97	Osteopetrosis associated transmembrane protein 1

0.60	GO:0030316	osteoclast differentiation
0.33	GO:0031204	posttranslational protein targeting to membrane, translocation
0.33	GO:0034220	ion transmembrane transport

0.33

GO:0005515

protein binding

0.50	GO:0005829	cytosol
0.37	GO:0005765	lysosomal membrane
0.33	GO:0030176	integral component of endoplasmic reticulum membrane

sp|Q5ZMW5|RHG26_CHICK
Rho GTPase-activating protein 26
Search

ARHGAP26

0.94	Rho GTPase-activating protein 26

0.74	GO:0051056	regulation of small GTPase mediated signal transduction
0.73	GO:0043547	positive regulation of GTPase activity
0.71	GO:0030036	actin cytoskeleton organization
0.59	GO:0007165	signal transduction
0.34	GO:0007399	nervous system development

0.74	GO:0005096	GTPase activator activity
0.51	GO:0005543	phospholipid binding
0.34	GO:0005515	protein binding

0.40	GO:0005925	focal adhesion
0.38	GO:0005856	cytoskeleton
0.34	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q5ZMW6|MDM1_CHICK
Nuclear protein MDM1
Search

MDM1

0.96	Mdm1 nuclear protein homolog

0.85	GO:0046600	negative regulation of centriole replication
0.44	GO:0060041	retina development in camera-type eye
0.34	GO:0045494	photoreceptor cell maintenance

0.74

GO:0008017

microtubule binding

0.49	GO:0005814	centriole
0.48	GO:0005813	centrosome
0.43	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.38	GO:0005874	microtubule
0.34	GO:0097730	non-motile cilium
0.32	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q5ZQU2|NPAS2_CHICK
Neuronal PAS domain-containing protein 2
Search

NPAS2

0.96	Neuronal PAS domain-containing protein 2

0.57	GO:0045739	positive regulation of DNA repair
0.56	GO:0051775	response to redox state
0.56	GO:0006351	transcription, DNA-templated
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.53	GO:0060548	negative regulation of cell death
0.51	GO:1902680	positive regulation of RNA biosynthetic process
0.40	GO:0007623	circadian rhythm
0.38	GO:0032501	multicellular organismal process

0.66	GO:0046983	protein dimerization activity
0.59	GO:0003700	DNA binding transcription factor activity
0.58	GO:0051879	Hsp90 protein binding
0.48	GO:0003677	DNA binding
0.38	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0046872	metal ion binding
0.32	GO:0003735	structural constituent of ribosome

0.71	GO:0005667	transcription factor complex
0.59	GO:0005634	nucleus
0.49	GO:0005829	cytosol
0.48	GO:0043233	organelle lumen
0.43	GO:0044446	intracellular organelle part
0.32	GO:0005840	ribosome

tr|Q60GF6|Q60GF6_CHICK
Protein Wnt
Search

tr|Q643S1|Q643S1_CHICK
Crossveinless-2
Search

BMPER

0.95	BMP binding endothelial regulator

0.81	GO:0030510	regulation of BMP signaling pathway
0.80	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.79	GO:0048839	inner ear development
0.79	GO:0042118	endothelial cell activation
0.76	GO:0035295	tube development
0.75	GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation
0.75	GO:0072163	mesonephric epithelium development
0.73	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.73	GO:0010594	regulation of endothelial cell migration
0.73	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.56	GO:0050840	extracellular matrix binding
0.42	GO:0005515	protein binding

0.71	GO:0005615	extracellular space
0.52	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0016021	integral component of membrane

tr|Q645M5|Q645M5_CHICK
Amphiregulin
Search

AREG

0.97	Amphiregulin long form

0.60	GO:0007173	epidermal growth factor receptor signaling pathway
0.59	GO:0032355	response to estradiol
0.59	GO:0045740	positive regulation of DNA replication
0.59	GO:0060598	dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis
0.58	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.57	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation
0.57	GO:0060744	mammary gland branching involved in thelarche
0.56	GO:0008284	positive regulation of cell proliferation
0.56	GO:0060749	mammary gland alveolus development
0.51	GO:0007186	G-protein coupled receptor signaling pathway

0.50	GO:0005154	epidermal growth factor receptor binding
0.46	GO:0008083	growth factor activity
0.38	GO:0005125	cytokine activity

0.54	GO:0009986	cell surface
0.53	GO:0005615	extracellular space
0.46	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.35	GO:0012506	vesicle membrane
0.34	GO:0097708	intracellular vesicle
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0031984	organelle subcompartment

tr|Q64EU6|Q64EU6_CHICK
Betacellulin
Search

BTC

0.96	Betacellulin

0.72	GO:0008284	positive regulation of cell proliferation
0.71	GO:0043066	negative regulation of apoptotic process
0.55	GO:0007173	epidermal growth factor receptor signaling pathway
0.50	GO:0010469	regulation of receptor activity
0.45	GO:0035810	positive regulation of urine volume
0.44	GO:0060014	granulosa cell differentiation
0.44	GO:0001556	oocyte maturation
0.43	GO:0048145	regulation of fibroblast proliferation
0.43	GO:0045840	positive regulation of mitotic nuclear division
0.42	GO:0045597	positive regulation of cell differentiation

0.55	GO:0005154	epidermal growth factor receptor binding
0.51	GO:0008083	growth factor activity

0.47	GO:0005615	extracellular space
0.30	GO:0016020	membrane

sp|Q64HY5|SP8_CHICK
Transcription factor Sp8
Search

0.96	Specificity protein 8

0.57	GO:0030326	embryonic limb morphogenesis
0.52	GO:0009954	proximal/distal pattern formation
0.50	GO:0009953	dorsal/ventral pattern formation
0.46	GO:0006357	regulation of transcription by RNA polymerase II
0.43	GO:0035118	embryonic pectoral fin morphogenesis
0.43	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway
0.38	GO:0007480	imaginal disc-derived leg morphogenesis
0.37	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.47	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.36	GO:0046872	metal ion binding

0.43	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q65Z91|TSK_CHICK
Tsukushin
Search

TSKU

0.97	Tsukushi, small leucine rich proteoglycan

0.86	GO:0061073	ciliary body morphogenesis
0.85	GO:0021540	corpus callosum morphogenesis
0.85	GO:0021960	anterior commissure morphogenesis
0.85	GO:0021670	lateral ventricle development
0.79	GO:0030178	negative regulation of Wnt signaling pathway
0.60	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.54	GO:0060255	regulation of macromolecule metabolic process
0.37	GO:0006468	protein phosphorylation

0.54	GO:0004930	G-protein coupled receptor activity
0.37	GO:0004672	protein kinase activity
0.36	GO:0005515	protein binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.70	GO:0005615	extracellular space
0.45	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q66PG3|LARG1_CHICK
LARGE xylosyl- and glucuronyltransferase 1
Search

LARGE1

0.96	LARGE xylosyl- and glucuronyltransferase 1

0.58	GO:0035269	protein O-linked mannosylation
0.50	GO:0043403	skeletal muscle tissue regeneration
0.49	GO:0046716	muscle cell cellular homeostasis
0.48	GO:0060538	skeletal muscle organ development
0.35	GO:0006688	glycosphingolipid biosynthetic process
0.34	GO:0006044	N-acetylglucosamine metabolic process

0.64	GO:0016757	transferase activity, transferring glycosyl groups
0.50	GO:0030145	manganese ion binding
0.34	GO:0005515	protein binding

0.50	GO:0005794	Golgi apparatus
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0031984	organelle subcompartment
0.34	GO:0031301	integral component of organelle membrane

0.64

GO:0016757

sp|Q66PG4|LARG2_CHICK
LARGE xylosyl- and glucuronyltransferase 2
Search

0.90	To like-glycosyltransferase

0.57	GO:0035269	protein O-linked mannosylation
0.48	GO:0043403	skeletal muscle tissue regeneration
0.46	GO:0046716	muscle cell cellular homeostasis
0.46	GO:0060538	skeletal muscle organ development
0.35	GO:0006688	glycosphingolipid biosynthetic process
0.34	GO:0006044	N-acetylglucosamine metabolic process

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.48	GO:0030145	manganese ion binding
0.34	GO:0005515	protein binding

0.48	GO:0005794	Golgi apparatus
0.39	GO:0098588	bounding membrane of organelle
0.38	GO:0031984	organelle subcompartment
0.34	GO:0031301	integral component of organelle membrane

0.65

GO:0016757

tr|Q66VY4|Q66VY4_CHICK
Splicing factor 3a subunit 2
Search

SF3A2

0.82	Spliceosome-associated protein 62

0.49	GO:0006397	mRNA processing
0.46	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
0.45	GO:0022618	ribonucleoprotein complex assembly
0.38	GO:0048731	system development
0.38	GO:0031346	positive regulation of cell projection organization
0.38	GO:0010720	positive regulation of cell development
0.38	GO:0051962	positive regulation of nervous system development
0.37	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.37	GO:0045137	development of primary sexual characteristics
0.36	GO:0030154	cell differentiation

0.62	GO:0008270	zinc ion binding
0.50	GO:0003676	nucleic acid binding
0.36	GO:0008083	growth factor activity
0.34	GO:0005199	structural constituent of cell wall

0.61	GO:0005634	nucleus
0.46	GO:0120114	Sm-like protein family complex
0.45	GO:1902494	catalytic complex
0.45	GO:0030529	intracellular ribonucleoprotein complex
0.43	GO:0044446	intracellular organelle part
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0005576	extracellular region

sp|Q679P3|PDLI7_CHICK
PDZ and LIM domain protein 7
Search

PDLIM7

0.91	PDZ and LIM domain protein 7

0.42	GO:0043433	negative regulation of DNA binding transcription factor activity
0.41	GO:0001503	ossification
0.40	GO:0032880	regulation of protein localization
0.40	GO:0030036	actin cytoskeleton organization
0.40	GO:0007275	multicellular organism development
0.40	GO:0006913	nucleocytoplasmic transport
0.39	GO:0030154	cell differentiation
0.37	GO:0048771	tissue remodeling
0.37	GO:0002009	morphogenesis of an epithelium
0.36	GO:0048646	anatomical structure formation involved in morphogenesis

0.54	GO:0046872	metal ion binding
0.43	GO:0033613	activating transcription factor binding

0.48	GO:0097517	contractile actin filament bundle
0.48	GO:0042641	actomyosin
0.45	GO:0031941	filamentous actin
0.43	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0005913	cell-cell adherens junction
0.42	GO:0001726	ruffle
0.42	GO:0005925	focal adhesion
0.42	GO:0030864	cortical actin cytoskeleton
0.39	GO:0030018	Z disc
0.37	GO:0005634	nucleus

tr|Q67BJ2|Q67BJ2_CHICK
Neprilysin
Search

MME

0.91	Membrane metallo-endopeptidase

0.61	GO:0006508	proteolysis
0.60	GO:0071492	cellular response to UV-A
0.59	GO:0071493	cellular response to UV-B
0.59	GO:0046449	creatinine metabolic process
0.59	GO:0090399	replicative senescence
0.58	GO:0050435	amyloid-beta metabolic process
0.57	GO:0019233	sensory perception of pain
0.55	GO:0001822	kidney development
0.53	GO:0071345	cellular response to cytokine stimulus
0.39	GO:0097242	amyloid-beta clearance

0.70	GO:0004222	metalloendopeptidase activity
0.47	GO:0008238	exopeptidase activity
0.46	GO:0042277	peptide binding
0.46	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding

0.56	GO:0005903	brush border
0.56	GO:0044306	neuron projection terminus
0.54	GO:0008021	synaptic vesicle
0.54	GO:0030425	dendrite
0.54	GO:0030424	axon
0.42	GO:0005886	plasma membrane
0.37	GO:0005615	extracellular space
0.36	GO:0005925	focal adhesion
0.36	GO:1903561	extracellular vesicle
0.35	GO:0030667	secretory granule membrane

0.70

GO:0004222

tr|Q67ER3|Q67ER3_CHICK
Zinc finger protein 183
Search

RNF113A

0.66	Zinc finger protein 183

0.51	GO:0034247	snoRNA splicing
0.48	GO:0045292	mRNA cis splicing, via spliceosome

0.54	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.33	GO:0016874	ligase activity

0.48

GO:0005684

U2-type spliceosomal complex

0.33

GO:0016874

tr|Q684L7|Q684L7_CHICK
Zona pellucida protein
Search

ZPAX

0.92	Egg envelope component ZPAX

0.42	GO:0060468	prevention of polyspermy
0.41	GO:0007339	binding of sperm to zona pellucida

0.58	GO:0005576	extracellular region
0.41	GO:0005771	multivesicular body
0.38	GO:0005783	endoplasmic reticulum
0.35	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q6A2A9|Q6A2A9_CHICK
Transcription factor LSox5-II
Search

SOX5

0.90	transcription factor SOX-5

0.47	GO:2000741	positive regulation of mesenchymal stem cell differentiation
0.46	GO:0032332	positive regulation of chondrocyte differentiation
0.46	GO:0055059	asymmetric neuroblast division
0.44	GO:0071560	cellular response to transforming growth factor beta stimulus
0.38	GO:0060164	regulation of timing of neuron differentiation
0.37	GO:0048709	oligodendrocyte differentiation
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:0051216	cartilage development
0.37	GO:0021953	central nervous system neuron differentiation
0.37	GO:0001701	in utero embryonic development

0.55	GO:0003677	DNA binding
0.36	GO:0005515	protein binding
0.36	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.36	GO:0005667	transcription factor complex
0.34	GO:0044446	intracellular organelle part

sp|Q6A2H4|IL10_CHICK
Interleukin-10
Search

IL10

0.92	Interleukin-10

0.75	GO:0010469	regulation of receptor activity
0.73	GO:0006955	immune response
0.64	GO:0002904	positive regulation of B cell apoptotic process
0.64	GO:0032800	receptor biosynthetic process
0.64	GO:0002740	negative regulation of cytokine secretion involved in immune response
0.63	GO:0051045	negative regulation of membrane protein ectodomain proteolysis
0.63	GO:0030889	negative regulation of B cell proliferation
0.62	GO:0032715	negative regulation of interleukin-6 production
0.61	GO:0051384	response to glucocorticoid
0.61	GO:0002875	negative regulation of chronic inflammatory response to antigenic stimulus

0.80	GO:0005125	cytokine activity
0.42	GO:0005141	interleukin-10 receptor binding
0.34	GO:0008083	growth factor activity

0.66

GO:0005576

extracellular region

sp|Q6AW68|SC16B_CHICK
Protein transport protein Sec16B
Search

SEC16B

0.64	SEC16 homolog B, endoplasmic reticulum export factor

0.83	GO:0048208	COPII vesicle coating
0.63	GO:0015031	protein transport
0.55	GO:0070863	positive regulation of protein exit from endoplasmic reticulum
0.52	GO:0016559	peroxisome fission
0.52	GO:0007029	endoplasmic reticulum organization
0.47	GO:0010628	positive regulation of gene expression

0.33

GO:0005509

calcium ion binding

0.72	GO:0000139	Golgi membrane
0.68	GO:0005783	endoplasmic reticulum

sp|Q6B3N0|HXA5_CHICK
Homeobox protein Hox-A5
Search

HOXA5

0.95	Homeobox protein Hox-A5

0.69	GO:0007275	multicellular organism development
0.58	GO:0002069	columnar/cuboidal epithelial cell maturation
0.57	GO:0010870	positive regulation of receptor biosynthetic process
0.57	GO:0045647	negative regulation of erythrocyte differentiation
0.57	GO:0060638	mesenchymal-epithelial cell signaling
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:0003016	respiratory system process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0033599	regulation of mammary gland epithelial cell proliferation

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0003690	double-stranded DNA binding
0.48	GO:0035326	enhancer binding
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.43	GO:0005829	cytosol
0.42	GO:0043233	organelle lumen
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0044446	intracellular organelle part

tr|Q6B7Z7|Q6B7Z7_CHICK
Histone stem-loop bindng protein
Search

SLBP

0.94	histone RNA hairpin-binding protein isoform X1

0.57	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage
0.53	GO:0033260	nuclear DNA replication
0.53	GO:0044770	cell cycle phase transition
0.50	GO:0051028	mRNA transport
0.40	GO:0031290	retinal ganglion cell axon guidance
0.40	GO:0003407	neural retina development
0.40	GO:0046530	photoreceptor cell differentiation
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0016567	protein ubiquitination

0.76	GO:0003729	mRNA binding
0.59	GO:0071207	histone pre-mRNA stem-loop binding
0.35	GO:0071208	histone pre-mRNA DCP binding
0.34	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0005515	protein binding

0.57	GO:0071204	histone pre-mRNA 3'end processing complex
0.50	GO:0005730	nucleolus
0.48	GO:0005829	cytosol
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|Q6B842|Q6B842_CHICK
Carnitine palmitoyltransferase I
Search

CPT1A

0.90	Carnitine palmitoyltransferase I

0.52	GO:0009437	carnitine metabolic process
0.50	GO:0001676	long-chain fatty acid metabolic process
0.50	GO:0030855	epithelial cell differentiation
0.41	GO:0032000	positive regulation of fatty acid beta-oxidation
0.41	GO:0042755	eating behavior
0.40	GO:0071398	cellular response to fatty acid
0.40	GO:0050796	regulation of insulin secretion
0.39	GO:0006641	triglyceride metabolic process
0.39	GO:0051260	protein homooligomerization
0.39	GO:0014070	response to organic cyclic compound

0.62	GO:0016746	transferase activity, transferring acyl groups
0.38	GO:0042802	identical protein binding

0.43	GO:0031966	mitochondrial membrane
0.43	GO:0019866	organelle inner membrane
0.39	GO:0031968	organelle outer membrane
0.39	GO:0031301	integral component of organelle membrane
0.34	GO:0005789	endoplasmic reticulum membrane

0.62

EC:2.3

GO:0016746

tr|Q6DMS2|Q6DMS2_CHICK
Transient receptor potential cation channel subfamily C member 1 isoform alpha
Search

TRPC1

0.97	Short transient receptor potential channel 1

0.76	GO:0070588	calcium ion transmembrane transport
0.58	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.57	GO:0042438	melanin biosynthetic process
0.56	GO:0051592	response to calcium ion
0.48	GO:0046847	filopodium assembly
0.47	GO:0006828	manganese ion transport
0.47	GO:0001570	vasculogenesis
0.46	GO:0001525	angiogenesis
0.37	GO:0046541	saliva secretion
0.36	GO:0044057	regulation of system process

0.78	GO:0005262	calcium channel activity
0.57	GO:0070679	inositol 1,4,5 trisphosphate binding
0.38	GO:0044325	ion channel binding

0.53	GO:0043235	receptor complex
0.44	GO:0005886	plasma membrane
0.37	GO:0043034	costamere
0.36	GO:0030017	sarcomere
0.36	GO:0045121	membrane raft
0.34	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|Q6DV79|STAT3_CHICK
Signal transducer and activator of transcription 3
Search

STAT3

0.69	Signal transducer and activator of transcription

0.61	GO:0007165	signal transduction
0.58	GO:1904685	positive regulation of metalloendopeptidase activity
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0006355	regulation of transcription, DNA-templated
0.56	GO:0072540	T-helper 17 cell lineage commitment
0.56	GO:0042755	eating behavior
0.56	GO:0060019	radial glial cell differentiation
0.56	GO:1905564	positive regulation of vascular endothelial cell proliferation
0.56	GO:2001223	negative regulation of neuron migration
0.56	GO:0045820	negative regulation of glycolytic process

0.64	GO:0004871	signal transducer activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.55	GO:0001103	RNA polymerase II repressing transcription factor binding
0.53	GO:0019903	protein phosphatase binding
0.51	GO:0019901	protein kinase binding
0.50	GO:0003682	chromatin binding
0.50	GO:0001067	regulatory region nucleic acid binding
0.49	GO:0042803	protein homodimerization activity
0.38	GO:0031730	CCR5 chemokine receptor binding

0.61	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.48	GO:0005737	cytoplasm
0.48	GO:0000785	chromatin
0.46	GO:0070013	intracellular organelle lumen
0.41	GO:0005886	plasma membrane
0.35	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

tr|Q6E236|Q6E236_CHICK
Homeodomain transcription factor
Search

OTX2

0.88	Orthodenticle homeobox 2

0.70	GO:0007275	multicellular organism development
0.62	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.62	GO:0000904	cell morphogenesis involved in differentiation
0.60	GO:0120036	plasma membrane bounded cell projection organization
0.60	GO:0045944	positive regulation of transcription by RNA polymerase II
0.60	GO:0006366	transcription by RNA polymerase II
0.57	GO:0006935	chemotaxis
0.56	GO:0006928	movement of cell or subcellular component
0.55	GO:0006461	protein complex assembly
0.45	GO:2000543	positive regulation of gastrulation

0.64	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0001012	RNA polymerase II regulatory region DNA binding
0.57	GO:0003690	double-stranded DNA binding
0.35	GO:0005515	protein binding

0.65	GO:0030426	growth cone
0.61	GO:0005634	nucleus
0.49	GO:0043234	protein complex

sp|Q6EE31|TCPQ_CHICK
T-complex protein 1 subunit theta
Search

CCT8

0.80	T-complex protein 1 subunit theta

0.69	GO:0006457	protein folding
0.53	GO:1904869	regulation of protein localization to Cajal body
0.53	GO:1904851	positive regulation of establishment of protein localization to telomere
0.53	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.51	GO:0032212	positive regulation of telomere maintenance via telomerase
0.51	GO:0046931	pore complex assembly
0.51	GO:0007339	binding of sperm to zona pellucida
0.50	GO:1900182	positive regulation of protein localization to nucleus
0.49	GO:0050821	protein stabilization
0.49	GO:1901998	toxin transport

0.71	GO:0051082	unfolded protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0045296	cadherin binding
0.47	GO:0044183	protein binding involved in protein folding
0.33	GO:0042623	ATPase activity, coupled

0.54	GO:0005832	chaperonin-containing T-complex
0.52	GO:0002199	zona pellucida receptor complex
0.49	GO:0044297	cell body
0.49	GO:0005815	microtubule organizing center
0.48	GO:0045111	intermediate filament cytoskeleton
0.46	GO:0005874	microtubule
0.45	GO:0005654	nucleoplasm
0.38	GO:0005929	cilium
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen

sp|Q6GVH4|GGNB2_CHICK
Gametogenetin-binding protein 2
Search

GGNBP2

0.89	Gametogenetin-binding protein 2

0.72	GO:0033140	negative regulation of peptidyl-serine phosphorylation of STAT protein
0.69	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein
0.67	GO:0061099	negative regulation of protein tyrosine kinase activity
0.63	GO:0060716	labyrinthine layer blood vessel development
0.62	GO:0007283	spermatogenesis
0.62	GO:0008285	negative regulation of cell proliferation
0.57	GO:0030154	cell differentiation
0.54	GO:0010629	negative regulation of gene expression
0.42	GO:0055114	oxidation-reduction process

0.43	GO:0016491	oxidoreductase activity
0.41	GO:0005515	protein binding

0.54	GO:0005634	nucleus
0.53	GO:0031410	cytoplasmic vesicle
0.30	GO:0016020	membrane

0.43

GO:0016491

sp|Q6GXJ1|GLL4_CHICK
Gallinacin-4
Search

0.56	Avian beta-defensin 4

0.69	GO:0050830	defense response to Gram-positive bacterium
0.68	GO:0050829	defense response to Gram-negative bacterium
0.68	GO:0050832	defense response to fungus

0.59	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

tr|Q6IEC5|Q6IEC5_CHICK
Putative ISG12(2) protein
Search

0.66	Interferon, alpha-inducible protein 6

0.30

GO:0044425

membrane part

sp|Q6IMM1|DJC27_CHICK
DnaJ homolog subfamily C member 27
Search

DNAJC27

0.97	Rab and DnaJ domain-containing

0.59	GO:0071701	regulation of MAPK export from nucleus
0.54	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.33	GO:0042981	regulation of apoptotic process
0.32	GO:0006468	protein phosphorylation

0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.31	GO:0008144	drug binding

0.45	GO:0005634	nucleus
0.44	GO:0005739	mitochondrion
0.33	GO:1902554	serine/threonine protein kinase complex
0.32	GO:0000428	DNA-directed RNA polymerase complex
0.32	GO:0005667	transcription factor complex
0.32	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

EC:2.7.11.23

GO:0008353

sp|Q6ITC7|RS13_CHICK
40S ribosomal protein S13
Search

RPS13

0.71	Ribosomal protein S13

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.49	GO:0033119	negative regulation of RNA splicing
0.37	GO:0048015	phosphatidylinositol-mediated signaling
0.37	GO:0046854	phosphatidylinositol phosphorylation
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.64	GO:0003735	structural constituent of ribosome
0.47	GO:0048027	mRNA 5'-UTR binding
0.46	GO:0070181	small ribosomal subunit rRNA binding
0.36	GO:1990932	5.8S rRNA binding
0.35	GO:0035091	phosphatidylinositol binding
0.35	GO:0016301	kinase activity
0.34	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.47	GO:0005730	nucleolus
0.47	GO:0044445	cytosolic part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.32

GO:0016787

sp|Q6IV18|GLL13_CHICK
Gallinacin-13
Search

0.74

Defensin

0.72	GO:0006952	defense response
0.39	GO:0009617	response to bacterium

0.66

GO:0005576

extracellular region

sp|Q6IV20|GLL11_CHICK
Gallinacin-11
Search

0.72	GO:0006952	defense response
0.41	GO:0009617	response to bacterium

0.66

GO:0005576

extracellular region

sp|Q6IV23|GLL8_CHICK
Gallinacin-8
Search

0.96	Avian beta-defensin 8

0.72	GO:0006952	defense response
0.45	GO:0009617	response to bacterium

0.66

GO:0005576

extracellular region

sp|Q6IV26|GLL5_CHICK
Gallinacin-5
Search

0.76	Avian beta-defensin 5

0.72	GO:0006952	defense response
0.39	GO:0009617	response to bacterium

0.66

GO:0005576

extracellular region

sp|Q6IVA4|UBA5_CHICK
Ubiquitin-like modifier-activating enzyme 5
Search

UBA5

0.90	Ubiquitin like modifier activating enzyme 5

0.59	GO:0071569	protein ufmylation
0.55	GO:0033146	regulation of intracellular estrogen receptor signaling pathway
0.52	GO:0034976	response to endoplasmic reticulum stress
0.34	GO:0007626	locomotory behavior
0.33	GO:0040011	locomotion

0.73	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.47	GO:0005829	cytosol
0.42	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

tr|Q6IYE9|Q6IYE9_CHICK
Thrombopoietin
Search

THPO

0.97	Thrombopoietin

0.80	GO:0008283	cell proliferation
0.76	GO:0010469	regulation of receptor activity
0.34	GO:0055085	transmembrane transport

0.81	GO:0005125	cytokine activity
0.79	GO:0005179	hormone activity
0.42	GO:0005128	erythropoietin receptor binding

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|Q6J211|Q6J211_CHICK
ZFP313
Search

RNF114

0.71	Ring finger protein 114

0.51	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.50	GO:0000209	protein polyubiquitination
0.40	GO:0007283	spermatogenesis
0.38	GO:0030154	cell differentiation
0.38	GO:0007275	multicellular organism development
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.52	GO:0031624	ubiquitin conjugating enzyme binding
0.48	GO:0046872	metal ion binding
0.48	GO:0061630	ubiquitin protein ligase activity
0.40	GO:0016874	ligase activity
0.37	GO:0003676	nucleic acid binding
0.33	GO:0003735	structural constituent of ribosome
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0016787	hydrolase activity

0.47	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.36	GO:0005634	nucleus
0.32	GO:0005840	ribosome

0.40

GO:0016874

tr|Q6J613|Q6J613_CHICK
Invariant chain isoform p41
Search

CD74

0.93	Major histocompatibility complex class II invariant chain

0.80	GO:0070206	protein trimerization
0.74	GO:0019882	antigen processing and presentation
0.70	GO:0006955	immune response
0.66	GO:0006886	intracellular protein transport
0.56	GO:0035691	macrophage migration inhibitory factor signaling pathway
0.55	GO:0002905	regulation of mature B cell apoptotic process
0.55	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production
0.55	GO:0002606	positive regulation of dendritic cell antigen processing and presentation
0.55	GO:0060907	positive regulation of macrophage cytokine production
0.54	GO:0045059	positive thymic T cell selection

0.85	GO:0042289	MHC class II protein binding
0.59	GO:0035718	macrophage migration inhibitory factor binding
0.54	GO:0050998	nitric-oxide synthase binding
0.54	GO:0023026	MHC class II protein complex binding
0.52	GO:0001540	amyloid-beta binding
0.52	GO:0044183	protein binding involved in protein folding
0.50	GO:0004896	cytokine receptor activity
0.49	GO:0042609	CD4 receptor binding
0.45	GO:0042288	MHC class I protein binding
0.42	GO:0005509	calcium ion binding

0.56	GO:0035693	NOS2-CD74 complex
0.55	GO:0035692	macrophage migration inhibitory factor receptor complex
0.53	GO:0005771	multivesicular body
0.51	GO:0009986	cell surface
0.50	GO:0042611	MHC protein complex
0.49	GO:0005764	lysosome
0.49	GO:0005783	endoplasmic reticulum
0.48	GO:0098552	side of membrane
0.47	GO:0005794	Golgi apparatus
0.37	GO:0005840	ribosome

sp|Q6JHU7|P3H2_CHICK
Prolyl 3-hydroxylase 2
Search

P3H2

0.97	Prolyl 3-hydroxylase 2

0.57	GO:0032963	collagen metabolic process
0.56	GO:0018126	protein hydroxylation
0.52	GO:0008285	negative regulation of cell proliferation
0.51	GO:0055114	oxidation-reduction process
0.50	GO:0018208	peptidyl-proline modification
0.41	GO:1901874	negative regulation of post-translational protein modification
0.39	GO:0060348	bone development
0.38	GO:0050821	protein stabilization
0.38	GO:0050708	regulation of protein secretion
0.37	GO:0006457	protein folding

0.76	GO:0031418	L-ascorbic acid binding
0.66	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.61	GO:0005506	iron ion binding
0.49	GO:0051213	dioxygenase activity
0.43	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0005518	collagen binding

0.54	GO:0005604	basement membrane
0.50	GO:0005783	endoplasmic reticulum
0.48	GO:0005794	Golgi apparatus
0.40	GO:0016528	sarcoplasm
0.34	GO:0070062	extracellular exosome
0.34	GO:0043233	organelle lumen
0.33	GO:0005634	nucleus
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005886	plasma membrane
0.32	GO:0032991	macromolecular complex

0.66

GO:0016705

sp|Q6JHU8|P3H1_CHICK
Prolyl 3-hydroxylase 1
Search

P3H1

0.97	LOW QUALITY PROTEIN: prolyl 3-hydroxylase 1

0.58	GO:0018126	protein hydroxylation
0.57	GO:1901874	negative regulation of post-translational protein modification
0.53	GO:0060348	bone development
0.52	GO:0032963	collagen metabolic process
0.51	GO:0055114	oxidation-reduction process
0.51	GO:0050821	protein stabilization
0.51	GO:0050708	regulation of protein secretion
0.47	GO:0018208	peptidyl-proline modification
0.47	GO:0006457	protein folding
0.44	GO:0008285	negative regulation of cell proliferation

0.77	GO:0031418	L-ascorbic acid binding
0.66	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.61	GO:0005506	iron ion binding
0.46	GO:0051213	dioxygenase activity
0.41	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0005518	collagen binding

0.51	GO:0005783	endoplasmic reticulum
0.46	GO:0005604	basement membrane
0.41	GO:0005794	Golgi apparatus
0.37	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.34	GO:0016528	sarcoplasm
0.34	GO:0032991	macromolecular complex
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005886	plasma membrane

0.66

GO:0016705

tr|Q6JHX4|Q6JHX4_CHICK
R-Ras3
Search

MRAS

0.97	Muscle RAS oncogene homolog

0.61	GO:0007165	signal transduction
0.53	GO:1990830	cellular response to leukemia inhibitory factor
0.37	GO:0061817	endoplasmic reticulum-plasma membrane tethering
0.36	GO:0006869	lipid transport
0.34	GO:0007517	muscle organ development
0.34	GO:0030036	actin cytoskeleton organization
0.33	GO:0043066	negative regulation of apoptotic process

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.58	GO:0030742	GTP-dependent protein binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0008289	lipid binding

0.36	GO:0070062	extracellular exosome
0.34	GO:0005886	plasma membrane
0.32	GO:0005622	intracellular

tr|Q6JLB2|Q6JLB2_CHICK
Proteasome subunit beta type
Search

PSMB1

0.53	Proteasome subunit beta type

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.35	GO:0043632	modification-dependent macromolecule catabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0043312	neutrophil degranulation

0.77	GO:0070003	threonine-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding

0.76	GO:0005839	proteasome core complex
0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0070013	intracellular organelle lumen
0.34	GO:0097708	intracellular vesicle
0.33	GO:0044446	intracellular organelle part
0.33	GO:0012505	endomembrane system

sp|Q6K1L7|EIF1A_CHICK
Probable RNA-binding protein EIF1AD
Search

EIF1AD

0.94	Eukaryotic translation initiation factor 1A domain containing

0.72	GO:0006413	translational initiation
0.34	GO:0007020	microtubule nucleation
0.32	GO:0006508	proteolysis

0.72	GO:0003743	translation initiation factor activity
0.34	GO:0043015	gamma-tubulin binding
0.33	GO:0008234	cysteine-type peptidase activity

0.41	GO:0005634	nucleus
0.34	GO:0000922	spindle pole
0.34	GO:0005815	microtubule organizing center

0.33

GO:0008234

tr|Q6LC82|Q6LC82_CHICK
GTPase cRac1A
Search

RAC1

0.81	Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

0.76	GO:0007264	small GTPase mediated signal transduction
0.52	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.52	GO:0032707	negative regulation of interleukin-23 production
0.51	GO:0048012	hepatocyte growth factor receptor signaling pathway
0.51	GO:0010592	positive regulation of lamellipodium assembly
0.51	GO:0060263	regulation of respiratory burst
0.50	GO:0051894	positive regulation of focal adhesion assembly
0.50	GO:0090023	positive regulation of neutrophil chemotaxis
0.50	GO:0097178	ruffle assembly
0.50	GO:0030032	lamellipodium assembly

0.67	GO:0003924	GTPase activity
0.65	GO:0005525	GTP binding
0.51	GO:0031996	thioesterase binding
0.47	GO:0019901	protein kinase binding
0.44	GO:0051022	Rho GDP-dissociation inhibitor binding
0.40	GO:0048306	calcium-dependent protein binding
0.40	GO:0030742	GTP-dependent protein binding
0.39	GO:0051117	ATPase binding
0.39	GO:0042826	histone deacetylase binding
0.38	GO:0017137	Rab GTPase binding

0.50	GO:0005884	actin filament
0.49	GO:0043197	dendritic spine
0.49	GO:0055038	recycling endosome membrane
0.49	GO:0032587	ruffle membrane
0.48	GO:0030027	lamellipodium
0.47	GO:0005802	trans-Golgi network
0.47	GO:0036464	cytoplasmic ribonucleoprotein granule
0.40	GO:0042470	melanosome
0.40	GO:0097732	9+2 non-motile cilium
0.40	GO:0030426	growth cone

0.34

GO:0004402

tr|Q6PKI7|Q6PKI7_CHICK
Neuronal tryptophan hydroxylase
Search

TPH2

0.97	Neuronal tryptophan hydroxylase

0.84	GO:0042427	serotonin biosynthetic process
0.68	GO:0009072	aromatic amino acid family metabolic process
0.52	GO:0055114	oxidation-reduction process
0.39	GO:0071285	cellular response to lithium ion
0.38	GO:0046849	bone remodeling
0.38	GO:0045600	positive regulation of fat cell differentiation
0.38	GO:0014823	response to activity
0.38	GO:0043627	response to estrogen
0.38	GO:0051384	response to glucocorticoid
0.38	GO:0051592	response to calcium ion

0.84	GO:0004510	tryptophan 5-monooxygenase activity
0.62	GO:0005506	iron ion binding

0.50	GO:0043005	neuron projection
0.33	GO:0005829	cytosol

0.84

EC:1.14.16.4

GO:0004510

tr|Q6PKI8|Q6PKI8_CHICK
Phenylalanine hydroxylase
Search

PAH

0.64	Phenylalanine hydroxylase

0.78	GO:0006559	L-phenylalanine catabolic process
0.53	GO:0055114	oxidation-reduction process
0.45	GO:0071391	cellular response to estrogen stimulus
0.37	GO:0046189	phenol-containing compound biosynthetic process
0.37	GO:0040002	collagen and cuticulin-based cuticle development
0.37	GO:0006571	tyrosine biosynthetic process
0.36	GO:0006582	melanin metabolic process
0.36	GO:0008340	determination of adult lifespan
0.35	GO:0006569	tryptophan catabolic process
0.35	GO:0044550	secondary metabolite biosynthetic process

0.83	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
0.63	GO:0005506	iron ion binding
0.34	GO:0016597	amino acid binding
0.34	GO:0042803	protein homodimerization activity
0.32	GO:0048037	cofactor binding

0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol

0.83

EC:1.14.16

GO:0016714

sp|Q6PUF4|DHI1L_CHICK
Hydroxysteroid 11-beta-dehydrogenase 1-like protein
Search

HSD11B1L

0.66	11-beta-hydroxysteroid dehydrogenase long form

0.52	GO:0055114	oxidation-reduction process
0.41	GO:0030324	lung development
0.34	GO:0008202	steroid metabolic process
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.53	GO:0016491	oxidoreductase activity
0.33	GO:0003735	structural constituent of ribosome

0.45	GO:0005654	nucleoplasm
0.36	GO:0005576	extracellular region
0.33	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.53

GO:0016491

sp|Q6PVW7|ZPBP2_CHICK
Zona pellucida-binding protein 2
Search

ZPBP2

0.97	Zona pellucida binding protein 2 transcript variant 1

0.85	GO:0007339	binding of sperm to zona pellucida
0.63	GO:0001675	acrosome assembly

0.66	GO:0005576	extracellular region
0.63	GO:0002199	zona pellucida receptor complex
0.61	GO:0001669	acrosomal vesicle
0.58	GO:0044297	cell body
0.36	GO:0005634	nucleus
0.35	GO:0030667	secretory granule membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q6PVZ1|K1C14_CHICK
Keratin, type I cytoskeletal 14
Search

0.92	Putative nuclear envelope protein lamin intermediate filament superfamily

0.52	GO:0042633	hair cycle
0.52	GO:0045109	intermediate filament organization
0.49	GO:0030855	epithelial cell differentiation
0.49	GO:0048730	epidermis morphogenesis
0.48	GO:0051798	positive regulation of hair follicle development
0.48	GO:0098773	skin epidermis development
0.48	GO:0022404	molting cycle process
0.46	GO:0030307	positive regulation of cell growth
0.45	GO:0045727	positive regulation of translation
0.42	GO:0007568	aging

0.62	GO:0005198	structural molecule activity
0.52	GO:0032395	MHC class II receptor activity
0.50	GO:0042289	MHC class II protein binding
0.43	GO:1990254	keratin filament binding

0.79	GO:0005882	intermediate filament
0.42	GO:0045178	basal part of cell
0.39	GO:0071944	cell periphery
0.38	GO:0005737	cytoplasm
0.37	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.33	GO:0015629	actin cytoskeleton
0.33	GO:0036338	viral membrane
0.30	GO:0016020	membrane

tr|Q6PVZ5|Q6PVZ5_CHICK
Type II alpha-keratin IIA
Search

0.84	Type II alpha-keratin IIA

0.38	GO:0051803	negative regulation of cytolysis in other organism involved in symbiotic interaction
0.38	GO:0001898	regulation of cytolysis by symbiont of host cells
0.37	GO:2000536	negative regulation of entry of bacterium into host cell
0.37	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.37	GO:0050830	defense response to Gram-positive bacterium
0.37	GO:0051801	cytolysis in other organism involved in symbiotic interaction
0.37	GO:0045104	intermediate filament cytoskeleton organization
0.35	GO:0031424	keratinization
0.35	GO:0012501	programmed cell death
0.35	GO:0042060	wound healing

0.62	GO:0005198	structural molecule activity
0.33	GO:0005515	protein binding

0.83	GO:0045095	keratin filament
0.35	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q6PZ02|ATG4B_CHICK
Cysteine protease ATG4B
Search

ATG4B

0.59	Cysteine protease

0.77	GO:0006914	autophagy
0.65	GO:0015031	protein transport
0.61	GO:0051697	protein delipidation
0.61	GO:0006508	proteolysis
0.55	GO:0007033	vacuole organization
0.51	GO:0070925	organelle assembly
0.48	GO:0006501	C-terminal protein lipidation
0.47	GO:0061726	mitochondrion disassembly
0.43	GO:0090150	establishment of protein localization to membrane
0.42	GO:0046907	intracellular transport

0.75	GO:0004197	cysteine-type endopeptidase activity
0.34	GO:0005515	protein binding

0.49

GO:0005737

cytoplasm

0.75

EC:3.4.22

GO:0004197

tr|Q6Q123|Q6Q123_CHICK
THRSP-like protein
Search

0.95	Gastrulation-specific protein G12

0.85	GO:0051351	positive regulation of ligase activity
0.84	GO:0045723	positive regulation of fatty acid biosynthetic process
0.83	GO:0007026	negative regulation of microtubule depolymerization
0.73	GO:0051258	protein polymerization
0.42	GO:0006853	carnitine shuttle
0.40	GO:0006629	lipid metabolic process
0.38	GO:0010866	regulation of triglyceride biosynthetic process

0.79	GO:0008022	protein C-terminus binding
0.70	GO:0042802	identical protein binding
0.35	GO:0046983	protein dimerization activity

0.70	GO:0015630	microtubule cytoskeleton
0.66	GO:0005829	cytosol
0.61	GO:0005634	nucleus
0.48	GO:0099513	polymeric cytoskeletal fiber
0.35	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

tr|Q6Q247|Q6Q247_CHICK
Growth differentiation factor 9
Search

GDF9

0.97	Growth and differentiation factor 9 variant FecG-Embrapa

0.75	GO:0010469	regulation of receptor activity
0.59	GO:2000870	regulation of progesterone secretion
0.55	GO:0001555	oocyte growth
0.52	GO:0008284	positive regulation of cell proliferation
0.52	GO:0030308	negative regulation of cell growth
0.46	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.46	GO:0060395	SMAD protein signal transduction
0.45	GO:0030509	BMP signaling pathway
0.44	GO:0043408	regulation of MAPK cascade
0.43	GO:0042981	regulation of apoptotic process

0.78	GO:0008083	growth factor activity
0.46	GO:0005160	transforming growth factor beta receptor binding
0.46	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.38	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|Q6Q273|Q6Q273_CHICK
Prepro-urotensin II-related peptide
Search

UTS2B

0.97	Prepro-urotensin II-related peptide

0.83	GO:0008217	regulation of blood pressure
0.82	GO:0097746	regulation of blood vessel diameter
0.75	GO:0010469	regulation of receptor activity

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|Q6Q2J6|Q6Q2J6_CHICK
Preprourotensin II
Search

UTS2

0.97	Preprourotensin II

0.83	GO:0008217	regulation of blood pressure
0.83	GO:0097746	regulation of blood vessel diameter
0.76	GO:0010469	regulation of receptor activity

0.79

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

sp|Q6Q2W4|ZPBP1_CHICK
Zona pellucida-binding protein 1 (Fragment)
Search

ZPBP

0.97	LOW QUALITY PROTEIN: zona pellucida-binding protein 1

0.85	GO:0007339	binding of sperm to zona pellucida
0.40	GO:0001675	acrosome assembly

0.66	GO:0005576	extracellular region
0.45	GO:0001669	acrosomal vesicle
0.44	GO:0030667	secretory granule membrane
0.40	GO:0002199	zona pellucida receptor complex
0.39	GO:0044297	cell body
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q6QLQ5|CTHL1_CHICK
Cathelicidin-1
Search

0.91	Cathelicidin

0.72	GO:0006952	defense response
0.51	GO:0009617	response to bacterium
0.48	GO:0019835	cytolysis
0.48	GO:0008219	cell death
0.47	GO:0010629	negative regulation of gene expression
0.46	GO:0051673	membrane disruption in other organism
0.46	GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response
0.45	GO:0030593	neutrophil chemotaxis
0.45	GO:0042116	macrophage activation
0.41	GO:0010628	positive regulation of gene expression

0.50

GO:0001530

lipopolysaccharide binding

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q6QLQ7|GLL12_CHICK
Gallinacin-12
Search

AVBD12

0.70	Beta-defensin

0.73	GO:0045087	innate immune response
0.72	GO:0042742	defense response to bacterium

0.66

GO:0005576

extracellular region

sp|Q6QLQ9|GLL10_CHICK
Gallinacin-10
Search

0.75	Avian beta-defensin 10

0.72	GO:0006952	defense response
0.39	GO:0009620	response to fungus
0.38	GO:0009617	response to bacterium

0.66	GO:0005576	extracellular region
0.30	GO:0044425	membrane part
0.30	GO:0005623	cell

sp|Q6QLR1|GLL9_CHICK
Gallinacin-9
Search

0.74	Avian beta-defensin 9

0.72	GO:0006952	defense response
0.43	GO:0009617	response to bacterium
0.39	GO:0009620	response to fungus
0.38	GO:0031640	killing of cells of other organism

0.66	GO:0005576	extracellular region
0.33	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q6QLR2|GLL7_CHICK
Gallinacin-7
Search

0.83	Avian beta-defensin 7

0.72	GO:0006952	defense response
0.47	GO:0009617	response to bacterium
0.37	GO:0051801	cytolysis in other organism involved in symbiotic interaction
0.37	GO:0051851	modification by host of symbiont morphology or physiology

0.66	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q6QLR3|GLL6_CHICK
Gallinacin-6
Search

0.96	Avian beta-defensin 6

0.72	GO:0006952	defense response
0.57	GO:0009617	response to bacterium
0.46	GO:0051801	cytolysis in other organism involved in symbiotic interaction
0.46	GO:0051851	modification by host of symbiont morphology or physiology

0.66

GO:0005576

extracellular region

tr|Q6R2T1|Q6R2T1_CHICK
PS1D
Search

ZCCHC17

0.97	Nucleolar protein of

0.35	GO:0043486	histone exchange
0.34	GO:0006402	mRNA catabolic process
0.34	GO:0006658	phosphatidylserine metabolic process
0.34	GO:0035019	somatic stem cell population maintenance
0.34	GO:0006665	sphingolipid metabolic process
0.33	GO:0006396	RNA processing
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.61	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.34	GO:0004654	polyribonucleotide nucleotidyltransferase activity
0.34	GO:0005515	protein binding
0.33	GO:0000287	magnesium ion binding
0.33	GO:0004386	helicase activity

0.49	GO:0022625	cytosolic large ribosomal subunit
0.47	GO:0005730	nucleolus
0.33	GO:0016607	nuclear speck
0.32	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.7.7.8

GO:0004654

tr|Q6R3Q5|Q6R3Q5_CHICK
GM3 synthase
Search

ST3GAL5

0.95	Lactosylceramide alpha-2,3-sialyltransferase

0.83	GO:0097503	sialylation
0.74	GO:0006486	protein glycosylation
0.47	GO:0018196	peptidyl-asparagine modification
0.43	GO:0009311	oligosaccharide metabolic process
0.41	GO:0006688	glycosphingolipid biosynthetic process
0.35	GO:0001573	ganglioside metabolic process
0.35	GO:0046513	ceramide biosynthetic process

0.83	GO:0008373	sialyltransferase activity
0.35	GO:0004308	exo-alpha-sialidase activity

0.69	GO:0005794	Golgi apparatus
0.42	GO:0098588	bounding membrane of organelle
0.42	GO:0031984	organelle subcompartment
0.33	GO:0005887	integral component of plasma membrane
0.32	GO:0005576	extracellular region

0.83

GO:0008373

tr|Q6R6I2|Q6R6I2_CHICK
N-methyl-D-aspartate receptor type 1 subunit
Search

GRIN1

0.91	Glutamate ionotropic receptor NMDA type subunit 1

0.79	GO:0060079	excitatory postsynaptic potential
0.76	GO:0035235	ionotropic glutamate receptor signaling pathway
0.60	GO:0034220	ion transmembrane transport
0.52	GO:1905429	response to glycine
0.51	GO:0018964	propylene metabolic process
0.51	GO:0021586	pons maturation
0.50	GO:0001661	conditioned taste aversion
0.49	GO:0060134	prepulse inhibition
0.49	GO:0043278	response to morphine
0.49	GO:0008355	olfactory learning

0.81	GO:0005234	extracellularly glutamate-gated ion channel activity
0.76	GO:0004970	ionotropic glutamate receptor activity
0.52	GO:0016594	glycine binding
0.51	GO:0016595	glutamate binding
0.51	GO:0099094	ligand-gated cation channel activity
0.49	GO:0022843	voltage-gated cation channel activity
0.48	GO:0005262	calcium channel activity
0.47	GO:1904315	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
0.46	GO:0005516	calmodulin binding
0.45	GO:0005102	receptor binding

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.53	GO:0017146	NMDA selective glutamate receptor complex
0.49	GO:0030425	dendrite
0.48	GO:0044309	neuron spine
0.48	GO:0008021	synaptic vesicle
0.47	GO:0014069	postsynaptic density
0.45	GO:0009986	cell surface
0.43	GO:0005783	endoplasmic reticulum
0.39	GO:0044422	organelle part

sp|Q6R748|STXB1_CHICK
Syntaxin-binding protein 1
Search

STXBP1

0.94	Syntaxin-binding protein 1

0.80	GO:0006904	vesicle docking involved in exocytosis
0.54	GO:0032229	negative regulation of synaptic transmission, GABAergic
0.54	GO:0002576	platelet degranulation
0.53	GO:0099011	neuronal dense core vesicle exocytosis
0.53	GO:0007412	axon target recognition
0.53	GO:0070527	platelet aggregation
0.52	GO:0016188	synaptic vesicle maturation
0.52	GO:0060292	long term synaptic depression
0.52	GO:0045956	positive regulation of calcium ion-dependent exocytosis
0.51	GO:0007274	neuromuscular synaptic transmission

0.53	GO:0017075	syntaxin-1 binding
0.39	GO:0043274	phospholipase binding
0.38	GO:0047485	protein N-terminus binding
0.37	GO:0019901	protein kinase binding
0.37	GO:0019904	protein domain specific binding
0.36	GO:0042802	identical protein binding
0.34	GO:0003723	RNA binding

0.54	GO:0048787	presynaptic active zone membrane
0.53	GO:0031091	platelet alpha granule
0.50	GO:0045335	phagocytic vesicle
0.49	GO:0043209	myelin sheath
0.48	GO:0030424	axon
0.47	GO:0005829	cytosol
0.47	GO:0005654	nucleoplasm
0.42	GO:0005739	mitochondrion
0.38	GO:0043679	axon terminus
0.37	GO:0048471	perinuclear region of cytoplasm

sp|Q6RFL5|BSH_CHICK
Brain-specific homeobox protein homolog
Search

BSX

0.96	Hematopoietically-expressed homeobox protein hhex

0.59	GO:0042755	eating behavior
0.59	GO:0060056	mammary gland involution
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0007626	locomotory behavior
0.51	GO:1902680	positive regulation of RNA biosynthetic process
0.42	GO:0007420	brain development
0.41	GO:0048663	neuron fate commitment
0.36	GO:0006351	transcription, DNA-templated

0.64	GO:0043565	sequence-specific DNA binding
0.46	GO:0003700	DNA binding transcription factor activity
0.36	GO:0001012	RNA polymerase II regulatory region DNA binding
0.36	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding
0.33	GO:0030545	receptor regulator activity

0.61	GO:0005634	nucleus
0.52	GO:0005667	transcription factor complex
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q6TPK5|Q6TPK5_CHICK
Schwann cell-specific EGF-like repeat autocrine factor
Search

0.77	von Willebrand factor D and EGF domains

0.40	GO:0007219	Notch signaling pathway
0.38	GO:0030154	cell differentiation
0.37	GO:0001558	regulation of cell growth
0.37	GO:0007275	multicellular organism development
0.37	GO:0050793	regulation of developmental process
0.35	GO:0042742	defense response to bacterium
0.35	GO:0048661	positive regulation of smooth muscle cell proliferation
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.65	GO:0005509	calcium ion binding
0.38	GO:0005520	insulin-like growth factor binding
0.35	GO:0004872	receptor activity
0.34	GO:0045296	cadherin binding
0.34	GO:0008061	chitin binding
0.34	GO:0042802	identical protein binding
0.34	GO:0019899	enzyme binding

0.37	GO:0005576	extracellular region
0.34	GO:0043235	receptor complex
0.34	GO:0015629	actin cytoskeleton
0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q6TQF9|Q6TQF9_CHICK
Type IIb sodium phosphate cotransporter
Search

SLC34A2

0.95	Sodium-dependent phosphate transport protein 2B

0.81	GO:0044341	sodium-dependent phosphate transport
0.55	GO:0072506	trivalent inorganic anion homeostasis
0.55	GO:0072505	divalent inorganic anion homeostasis
0.55	GO:0055083	monovalent inorganic anion homeostasis
0.54	GO:0035725	sodium ion transmembrane transport
0.53	GO:0035435	phosphate ion transmembrane transport
0.53	GO:0030002	cellular anion homeostasis
0.52	GO:0043627	response to estrogen
0.47	GO:0001701	in utero embryonic development
0.46	GO:0010288	response to lead ion

0.81	GO:0015321	sodium-dependent phosphate transmembrane transporter activity
0.61	GO:0005436	sodium:phosphate symporter activity
0.51	GO:0031402	sodium ion binding
0.50	GO:0042301	phosphate ion binding
0.34	GO:0019904	protein domain specific binding
0.34	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.33	GO:0015370	solute:sodium symporter activity
0.33	GO:0005057	signal transducer activity, downstream of receptor
0.32	GO:0042803	protein homodimerization activity
0.32	GO:0032403	protein complex binding

0.58	GO:0016324	apical plasma membrane
0.55	GO:0005903	brush border
0.44	GO:0031982	vesicle
0.43	GO:0072686	mitotic spindle
0.43	GO:0016607	nuclear speck
0.40	GO:0045203	integral component of cell outer membrane
0.36	GO:0005737	cytoplasm
0.36	GO:0031253	cell projection membrane
0.34	GO:0005902	microvillus
0.34	GO:0016323	basolateral plasma membrane

0.34

GO:0004714

sp|Q6U1I9|SGK1_CHICK
Serine/threonine-protein kinase Sgk1
Search

SGK1

0.94	Serum/glucocorticoid regulated kinase 1

0.63	GO:0006468	protein phosphorylation
0.46	GO:0018209	peptidyl-serine modification
0.45	GO:0048812	neuron projection morphogenesis
0.45	GO:0006950	response to stress
0.43	GO:0051716	cellular response to stimulus
0.43	GO:0006915	apoptotic process
0.40	GO:0023052	signaling
0.39	GO:0007154	cell communication
0.37	GO:0050794	regulation of cellular process
0.37	GO:0051050	positive regulation of transport

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.52	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.46	GO:0035091	phosphatidylinositol binding
0.36	GO:0043423	3-phosphoinositide-dependent protein kinase binding
0.35	GO:0048156	tau protein binding
0.35	GO:0017081	chloride channel regulator activity

0.51	GO:0016607	nuclear speck
0.46	GO:0005829	cytosol
0.41	GO:0005783	endoplasmic reticulum
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.36	GO:0005739	mitochondrion
0.35	GO:0005886	plasma membrane
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0043005	neuron projection
0.30	GO:0016021	integral component of membrane

0.70

GO:0004674

sp|Q6U7I1|UBP7_CHICK
Ubiquitin carboxyl-terminal hydrolase 7
Search

USP7

0.75	Ubiquitin carboxyl-terminal hydrolase 7

0.76	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.55	GO:0010216	maintenance of DNA methylation
0.54	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.53	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.51	GO:0050821	protein stabilization
0.51	GO:0006283	transcription-coupled nucleotide-excision repair
0.45	GO:1904888	cranial skeletal system development
0.36	GO:0016570	histone modification
0.36	GO:1904353	regulation of telomere capping

0.76	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.53	GO:0002039	p53 binding
0.52	GO:0008022	protein C-terminus binding
0.51	GO:0031625	ubiquitin protein ligase binding
0.49	GO:0004197	cysteine-type endopeptidase activity
0.48	GO:0008134	transcription factor binding

0.46	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.42	GO:0043234	protein complex
0.35	GO:0005694	chromosome
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part

0.76

EC:3.4.19.12

GO:0036459

tr|Q6URH5|Q6URH5_CHICK
Gap junction protein
Search

GJB1

0.64	Gap junction beta-1 protein (Fragment)

0.60	GO:0007154	cell communication
0.39	GO:1905867	epididymis development
0.38	GO:0015868	purine ribonucleotide transport
0.36	GO:0016264	gap junction assembly
0.36	GO:0051259	protein oligomerization
0.34	GO:0055085	transmembrane transport
0.34	GO:0007399	nervous system development
0.33	GO:0023052	signaling

0.49	GO:0042803	protein homodimerization activity
0.40	GO:0005243	gap junction channel activity

0.83	GO:0005922	connexin complex
0.38	GO:0005737	cytoplasm
0.37	GO:0016328	lateral plasma membrane
0.35	GO:0012505	endomembrane system
0.34	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

tr|Q6VN51|Q6VN51_CHICK
Protein phospatase 3 regulatory subunit B alpha isoform type 1
Search

PPP3R1

0.93	Calcineurin B regulatory subunit

0.46	GO:0051531	NFAT protein import into nucleus
0.45	GO:0033173	calcineurin-NFAT signaling cascade
0.45	GO:0060487	lung epithelial cell differentiation
0.44	GO:0001569	branching involved in blood vessel morphogenesis
0.44	GO:0022011	myelination in peripheral nervous system
0.44	GO:0001837	epithelial to mesenchymal transition
0.42	GO:0007507	heart development
0.41	GO:0006470	protein dephosphorylation
0.39	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

0.70	GO:0005509	calcium ion binding
0.42	GO:0016018	cyclosporin A binding
0.41	GO:0004721	phosphoprotein phosphatase activity
0.39	GO:0019904	protein domain specific binding
0.38	GO:0043130	ubiquitin binding
0.35	GO:0019899	enzyme binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0005516	calmodulin binding

0.43	GO:0042383	sarcolemma
0.41	GO:0005955	calcineurin complex
0.36	GO:0005829	cytosol
0.33	GO:0005654	nucleoplasm
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.41

EC:3.1.3.16

GO:0004721

sp|Q6VYA3|SOSD1_CHICK
Sclerostin domain-containing protein 1
Search

SOSTDC1

0.97	Uterine sensitization-associated protein-1

0.56	GO:2000016	negative regulation of determination of dorsal identity
0.55	GO:0030514	negative regulation of BMP signaling pathway
0.54	GO:0010454	negative regulation of cell fate commitment
0.54	GO:0045662	negative regulation of myoblast differentiation
0.53	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.53	GO:0060648	mammary gland bud morphogenesis
0.52	GO:0030509	BMP signaling pathway
0.51	GO:0042475	odontogenesis of dentin-containing tooth
0.51	GO:0031069	hair follicle morphogenesis
0.51	GO:0030279	negative regulation of ossification

0.55	GO:0098821	BMP receptor activity
0.55	GO:0036122	BMP binding
0.37	GO:0008134	transcription factor binding

0.73	GO:0005615	extracellular space
0.37	GO:0031012	extracellular matrix

tr|Q6W8X3|Q6W8X3_CHICK
High mobility group A1b
Search

HMGA1

0.97	High mobility group protein HMG-I/HMG-Y

0.62	GO:0090402	oncogene-induced cell senescence
0.62	GO:0035986	senescence-associated heterochromatin focus assembly
0.60	GO:2000774	positive regulation of cellular senescence
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0008285	negative regulation of cell proliferation
0.51	GO:1902680	positive regulation of RNA biosynthetic process
0.51	GO:0009615	response to virus
0.50	GO:1902679	negative regulation of RNA biosynthetic process

0.61	GO:0042975	peroxisome proliferator activated receptor binding
0.60	GO:0046965	retinoid X receptor binding
0.57	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.56	GO:0003680	AT DNA binding
0.55	GO:0001158	enhancer sequence-specific DNA binding
0.49	GO:0019899	enzyme binding
0.47	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity
0.42	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.41	GO:0051575	5'-deoxyribose-5-phosphate lyase activity
0.40	GO:0003682	chromatin binding

0.71	GO:0000785	chromatin
0.60	GO:0005634	nucleus
0.39	GO:0005667	transcription factor complex
0.38	GO:0005925	focal adhesion
0.34	GO:0005829	cytosol
0.34	GO:0043233	organelle lumen

0.47

EC:4.2.99.18

GO:0003906

tr|Q6XBN6|Q6XBN6_CHICK
Disabled-1 late isoform
Search

DAB1

0.92	Disabled1 transcript variant 2

0.85	GO:0021813	cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration
0.85	GO:0021589	cerebellum structural organization
0.84	GO:0097477	lateral motor column neuron migration
0.83	GO:0021942	radial glia guided migration of Purkinje cell
0.82	GO:0048712	negative regulation of astrocyte differentiation
0.80	GO:0051645	Golgi localization
0.79	GO:0007628	adult walking behavior
0.78	GO:0021517	ventral spinal cord development
0.78	GO:0050771	negative regulation of axonogenesis
0.78	GO:0046426	negative regulation of JAK-STAT cascade

0.51	GO:0043548	phosphatidylinositol 3-kinase binding
0.39	GO:0042169	SH2 domain binding
0.37	GO:0005543	phospholipid binding

0.72	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0005579	membrane attack complex
0.53	GO:0043231	intracellular membrane-bounded organelle
0.50	GO:0043005	neuron projection
0.50	GO:0005903	brush border
0.49	GO:0014069	postsynaptic density
0.49	GO:0043025	neuronal cell body
0.48	GO:0045177	apical part of cell
0.44	GO:0005829	cytosol

tr|Q6XFR1|Q6XFR1_CHICK
CD47 glycoprotein isoform A
Search

CD47

0.97	Leukocyte surface antigen CD47 isoform B

0.50	GO:0008228	opsonization
0.48	GO:0050766	positive regulation of phagocytosis
0.47	GO:0050729	positive regulation of inflammatory response
0.46	GO:0008284	positive regulation of cell proliferation
0.45	GO:0009617	response to bacterium
0.45	GO:0050870	positive regulation of T cell activation
0.40	GO:0007165	signal transduction

0.50

GO:0070053

thrombospondin receptor activity

0.46	GO:0070062	extracellular exosome
0.42	GO:0005887	integral component of plasma membrane

sp|Q6XK22|R9BP_CHICK
Regulator of G-protein signaling 9-binding protein
Search

RGS9BP

0.96	Regulator of G-protein signaling 9-binding protein A

0.61	GO:0050908	detection of light stimulus involved in visual perception
0.41	GO:0009968	negative regulation of signal transduction

0.59	GO:0001750	photoreceptor outer segment
0.36	GO:0060170	ciliary membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q6XL41|RHCG_CHICK
Ammonium transporter Rh type C
Search

RHCG

0.86	Rhesus blood group-associated glycoprotein C

0.77	GO:0072488	ammonium transmembrane transport
0.59	GO:0070634	transepithelial ammonium transport
0.51	GO:0006885	regulation of pH
0.50	GO:0006873	cellular ion homeostasis
0.47	GO:0015695	organic cation transport
0.41	GO:0097272	ammonia homeostasis
0.36	GO:0006814	sodium ion transport
0.35	GO:0015837	amine transport
0.34	GO:0030855	epithelial cell differentiation

0.77	GO:0008519	ammonium transmembrane transporter activity
0.58	GO:0030506	ankyrin binding
0.49	GO:0042802	identical protein binding

0.57	GO:0016324	apical plasma membrane
0.55	GO:0016323	basolateral plasma membrane
0.49	GO:0005887	integral component of plasma membrane
0.41	GO:0031410	cytoplasmic vesicle
0.37	GO:0012506	vesicle membrane
0.36	GO:0016327	apicolateral plasma membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0045178	basal part of cell
0.34	GO:0044446	intracellular organelle part

tr|Q6XLP9|Q6XLP9_CHICK
C-hairy1B
Search

HES1

0.89	BHLH-WRPW transcription factor

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0050767	regulation of neurogenesis
0.53	GO:0051961	negative regulation of nervous system development
0.53	GO:0010721	negative regulation of cell development
0.52	GO:0007219	Notch signaling pathway
0.52	GO:0021536	diencephalon development
0.51	GO:0043009	chordate embryonic development

0.68	GO:0046983	protein dimerization activity
0.55	GO:0003677	DNA binding
0.47	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0042826	histone deacetylase binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.45	GO:0051087	chaperone binding
0.45	GO:0042802	identical protein binding
0.39	GO:0008134	transcription factor binding
0.35	GO:0004565	beta-galactosidase activity
0.35	GO:0008432	JUN kinase binding

0.61	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome

0.35

EC:3.2.1.23

GO:0004565

sp|Q6XUX0|DUSTY_CHICK
Dual serine/threonine and tyrosine protein kinase
Search

DSTYK

0.96	Dual serine/threonine and tyrosine protein kinase

0.61	GO:0006468	protein phosphorylation
0.58	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway
0.55	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.54	GO:0044344	cellular response to fibroblast growth factor stimulus
0.52	GO:0033674	positive regulation of kinase activity
0.52	GO:0043066	negative regulation of apoptotic process
0.44	GO:0048568	embryonic organ development
0.44	GO:0018212	peptidyl-tyrosine modification
0.40	GO:0035556	intracellular signal transduction

0.62	GO:0004672	protein kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0016323	basolateral plasma membrane
0.56	GO:0016324	apical plasma membrane
0.43	GO:0030054	cell junction
0.42	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q6XXM1|CENPA_CHICK
Histone H3-like centromeric protein A
Search

CENPA

0.77	Centromeric protein A

0.60	GO:0061641	CENP-A containing chromatin organization
0.45	GO:0065004	protein-DNA complex assembly
0.44	GO:0051383	kinetochore organization
0.43	GO:0000132	establishment of mitotic spindle orientation
0.43	GO:0071459	protein localization to chromosome, centromeric region
0.42	GO:0000281	mitotic cytokinesis
0.42	GO:0031497	chromatin assembly
0.42	GO:0034728	nucleosome organization
0.41	GO:0070925	organelle assembly
0.41	GO:0043623	cellular protein complex assembly

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.43	GO:0031491	nucleosome binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.60	GO:0061638	CENP-A containing chromatin
0.58	GO:0000779	condensed chromosome, centromeric region
0.51	GO:0031974	membrane-enclosed lumen
0.44	GO:0000776	kinetochore
0.42	GO:0005721	pericentric heterochromatin
0.33	GO:0005829	cytosol

sp|Q6YI48|PTPRU_CHICK
Receptor-type tyrosine-protein phosphatase U
Search

PTPRU

0.88	Protein tyrosine phosphatase, receptor type U

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.57	GO:0034394	protein localization to cell surface
0.56	GO:0034109	homotypic cell-cell adhesion
0.55	GO:0060070	canonical Wnt signaling pathway
0.54	GO:0030336	negative regulation of cell migration
0.52	GO:0008285	negative regulation of cell proliferation
0.39	GO:0031100	animal organ regeneration
0.39	GO:0051384	response to glucocorticoid
0.38	GO:0030182	neuron differentiation

0.75	GO:0004725	protein tyrosine phosphatase activity
0.54	GO:0008013	beta-catenin binding

0.51	GO:0005911	cell-cell junction
0.30	GO:0016020	membrane

0.75

GO:0004725

sp|Q6YJI5|TRM11_CHICK
tRNA (guanine(10)-N2)-methyltransferase homolog
Search

TRMT11

0.94	tRNA methyltransferase 11 homolog

0.62	GO:0032259	methylation
0.38	GO:0008033	tRNA processing
0.35	GO:0009451	RNA modification
0.35	GO:0051382	kinetochore assembly
0.34	GO:0000278	mitotic cell cycle
0.33	GO:0044260	cellular macromolecule metabolic process

0.62	GO:0008168	methyltransferase activity
0.50	GO:0003676	nucleic acid binding
0.35	GO:0140101	catalytic activity, acting on a tRNA
0.34	GO:0046982	protein heterodimerization activity

0.30

GO:0031224

intrinsic component of membrane

0.62

GO:0008168

sp|Q6ZXC3|TRH_CHICK
Pro-thyrotropin-releasing hormone
Search

TRH

0.96	Pro-thyrotropin-releasing hormone-A

0.77	GO:0009755	hormone-mediated signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.45	GO:0014050	negative regulation of glutamate secretion
0.44	GO:0014054	positive regulation of gamma-aminobutyric acid secretion
0.44	GO:0001692	histamine metabolic process
0.43	GO:0042755	eating behavior
0.43	GO:0032024	positive regulation of insulin secretion
0.39	GO:0007628	adult walking behavior
0.34	GO:0051412	response to corticosterone
0.34	GO:2000252	negative regulation of feeding behavior

0.87	GO:0008437	thyrotropin-releasing hormone activity
0.35	GO:0046872	metal ion binding
0.33	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.41	GO:0030141	secretory granule
0.37	GO:0005634	nucleus
0.36	GO:0005886	plasma membrane

tr|Q6ZXD0|Q6ZXD0_CHICK
Alpha-2,8-sialyltransferase
Search

ST8SIA3

0.97	Z-linked ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3

0.83	GO:0097503	sialylation
0.74	GO:0006486	protein glycosylation
0.61	GO:0001574	ganglioside biosynthetic process
0.56	GO:0006491	N-glycan processing
0.51	GO:0009311	oligosaccharide metabolic process
0.46	GO:0046716	muscle cell cellular homeostasis
0.44	GO:0007517	muscle organ development
0.37	GO:0016051	carbohydrate biosynthetic process

0.83	GO:0008373	sialyltransferase activity
0.50	GO:0042802	identical protein binding
0.35	GO:0033691	sialic acid binding

0.69	GO:0005794	Golgi apparatus
0.37	GO:0098588	bounding membrane of organelle
0.36	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.83

GO:0008373

sp|Q701R0|SIAT2_CHICK
Beta-galactoside alpha-2,6-sialyltransferase 2
Search

ST6GAL2

0.97	Beta-galactoside alpha-2,6-sialyltransferase

0.83	GO:0097503	sialylation
0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.60	GO:0006464	cellular protein modification process
0.51	GO:0009311	oligosaccharide metabolic process
0.36	GO:0006054	N-acetylneuraminate metabolic process
0.34	GO:0040007	growth
0.34	GO:0007275	multicellular organism development

0.83	GO:0008373	sialyltransferase activity
0.32	GO:0050662	coenzyme binding

0.47	GO:0005794	Golgi apparatus
0.44	GO:0098588	bounding membrane of organelle
0.43	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.83

GO:0008373

tr|Q702H5|Q702H5_CHICK
CCXC chemokine receptor 1 like
Search

XCR1

0.95	Chemokine XC receptor

0.82	GO:0070098	chemokine-mediated signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.70	GO:0006935	chemotaxis
0.41	GO:0007155	cell adhesion
0.38	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.37	GO:0051283	negative regulation of sequestering of calcium ion
0.37	GO:0060401	cytosolic calcium ion transport
0.36	GO:0070588	calcium ion transmembrane transport
0.36	GO:0032501	multicellular organismal process
0.36	GO:0006954	inflammatory response

0.83	GO:0004950	chemokine receptor activity
0.44	GO:0019956	chemokine binding
0.37	GO:0004974	leukotriene receptor activity
0.34	GO:0032027	myosin light chain binding
0.34	GO:0004983	neuropeptide Y receptor activity
0.34	GO:0005044	scavenger receptor activity
0.34	GO:0043130	ubiquitin binding
0.34	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0003779	actin binding
0.33	GO:0015054	gastrin receptor activity

0.38	GO:0005654	nucleoplasm
0.36	GO:0009986	cell surface
0.35	GO:0005886	plasma membrane
0.34	GO:0005770	late endosome
0.34	GO:0005769	early endosome
0.34	GO:0031252	cell leading edge
0.34	GO:0005764	lysosome
0.33	GO:0098552	side of membrane
0.32	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

tr|Q703P0|Q703P0_CHICK
Corticotropin releasing hormone
Search

CRH

0.97	Corticotropin releasing hormone a

0.76	GO:0010469	regulation of receptor activity
0.56	GO:2000851	positive regulation of glucocorticoid secretion
0.56	GO:0051462	regulation of cortisol secretion
0.55	GO:0051461	positive regulation of corticotropin secretion
0.54	GO:0001963	synaptic transmission, dopaminergic
0.53	GO:2001025	positive regulation of response to drug
0.53	GO:1900449	regulation of glutamate receptor signaling pathway
0.53	GO:0006704	glucocorticoid biosynthetic process
0.52	GO:2001257	regulation of cation channel activity
0.52	GO:0035641	locomotory exploration behavior

0.79	GO:0005179	hormone activity
0.39	GO:0051430	corticotropin-releasing hormone receptor 1 binding
0.39	GO:0051431	corticotropin-releasing hormone receptor 2 binding
0.35	GO:0004601	peroxidase activity
0.33	GO:0004849	uridine kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.66	GO:0005576	extracellular region
0.39	GO:0043196	varicosity
0.38	GO:0043204	perikaryon
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.35	EC:1.11.1.7	GO:0004601
0.35	KEGG:R03532	GO:0004601

tr|Q70IK3|Q70IK3_CHICK
Helix-loop-helix protein E12
Search

TCF3

0.93	Transcription factor 3

0.56	GO:0033152	immunoglobulin V(D)J recombination
0.51	GO:0051091	positive regulation of DNA binding transcription factor activity
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:0000122	negative regulation of transcription by RNA polymerase II
0.46	GO:0045666	positive regulation of neuron differentiation
0.42	GO:0006351	transcription, DNA-templated
0.40	GO:0002326	B cell lineage commitment
0.39	GO:0030890	positive regulation of B cell proliferation
0.38	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.38	GO:0045787	positive regulation of cell cycle

0.67	GO:0046983	protein dimerization activity
0.56	GO:0043425	bHLH transcription factor binding
0.55	GO:0070644	vitamin D response element binding
0.54	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.54	GO:0070888	E-box binding
0.52	GO:0070491	repressing transcription factor binding
0.52	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0003713	transcription coactivator activity
0.50	GO:0042802	identical protein binding
0.38	GO:0035326	enhancer binding

0.50	GO:0005667	transcription factor complex
0.50	GO:0016607	nuclear speck
0.48	GO:0000790	nuclear chromatin
0.38	GO:0005737	cytoplasm
0.35	GO:0000786	nucleosome

sp|Q710A0|SPP24_CHICK
Secreted phosphoprotein 24
Search

SPP2

0.97	Secreted phosphoprotein 2

0.85	GO:0046849	bone remodeling
0.36	GO:0002576	platelet degranulation
0.35	GO:0043687	post-translational protein modification
0.35	GO:0001501	skeletal system development
0.35	GO:0010951	negative regulation of endopeptidase activity
0.34	GO:0006461	protein complex assembly

0.35

GO:0004866

endopeptidase inhibitor activity

0.66	GO:0005576	extracellular region
0.37	GO:0031089	platelet dense granule lumen
0.35	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

tr|Q71LH8|Q71LH8_CHICK
LIM domain-containing transcription factor
Search

LMO2

0.91	LIM domain only 2

0.53	GO:0097067	cellular response to thyroid hormone stimulus
0.52	GO:0042789	mRNA transcription by RNA polymerase II
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0035162	embryonic hemopoiesis
0.45	GO:0061304	retinal blood vessel morphogenesis
0.44	GO:0031101	fin regeneration
0.44	GO:0001935	endothelial cell proliferation
0.43	GO:0048821	erythrocyte development
0.39	GO:0032844	regulation of homeostatic process
0.38	GO:0002682	regulation of immune system process

0.54	GO:0046872	metal ion binding
0.52	GO:0043425	bHLH transcription factor binding
0.52	GO:0070888	E-box binding
0.51	GO:0001102	RNA polymerase II activating transcription factor binding
0.51	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.49	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.40	GO:0048037	cofactor binding
0.36	GO:0003682	chromatin binding
0.32	GO:0003707	steroid hormone receptor activity

0.47	GO:0005667	transcription factor complex
0.38	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q71R50|DHR11_CHICK
Dehydrogenase/reductase SDR family member 11
Search

DHRS11

0.90	Dehydrogenase/reductase SDR family member 11

0.53	GO:0006694	steroid biosynthetic process
0.50	GO:0055114	oxidation-reduction process
0.41	GO:0008210	estrogen metabolic process
0.39	GO:0042446	hormone biosynthetic process
0.34	GO:0044249	cellular biosynthetic process
0.34	GO:0001510	RNA methylation
0.33	GO:0006396	RNA processing

0.62	GO:0072555	17-beta-ketosteroid reductase activity
0.62	GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity
0.60	GO:0000253	3-keto sterol reductase activity
0.58	GO:0004303	estradiol 17-beta-dehydrogenase activity
0.34	GO:1901265	nucleoside phosphate binding
0.34	GO:0036094	small molecule binding
0.34	GO:0008173	RNA methyltransferase activity
0.33	GO:0003723	RNA binding

0.37	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.60

EC:1.1.1.270

GO:0000253

tr|Q71RI7|Q71RI7_CHICK
Guanine nucleotide-binding protein G11 alpha-subunit
Search

GNA11

0.86	G protein subunit alpha q

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.56	GO:0007603	phototransduction, visible light
0.55	GO:0009649	entrainment of circadian clock
0.54	GO:1905145	cellular response to acetylcholine
0.54	GO:1903831	signal transduction involved in cellular response to ammonium ion
0.54	GO:0001508	action potential
0.53	GO:0045634	regulation of melanocyte differentiation
0.51	GO:0048066	developmental pigmentation
0.49	GO:0001501	skeletal system development
0.49	GO:0071467	cellular response to pH

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.80	GO:0001664	G-protein coupled receptor binding
0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.64	GO:0004871	signal transducer activity
0.39	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity
0.39	GO:0005096	GTPase activator activity
0.36	GO:0046872	metal ion binding
0.35	GO:0002046	opsin binding

0.55	GO:0001750	photoreceptor outer segment
0.46	GO:1905360	GTPase complex
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.41	GO:0098797	plasma membrane protein complex
0.39	GO:0030425	dendrite
0.39	GO:0044297	cell body
0.38	GO:0005765	lysosomal membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0031965	nuclear membrane
0.35	GO:0097232	lamellar body membrane

0.39

EC:3.1.4.39

GO:0047391

tr|Q71SG4|Q71SG4_CHICK
Collapsin response mediator protein-1A
Search

CRMP1

0.95	Dihydropyrimidinase-related protein 1 isoform A

0.80	GO:0007411	axon guidance
0.75	GO:0000226	microtubule cytoskeleton organization
0.46	GO:0010975	regulation of neuron projection development
0.43	GO:0051491	positive regulation of filopodium assembly
0.43	GO:0048678	response to axon injury
0.43	GO:1904617	negative regulation of actin binding
0.43	GO:1904529	regulation of actin filament binding
0.42	GO:0051017	actin filament bundle assembly
0.41	GO:0045665	negative regulation of neuron differentiation
0.41	GO:0031345	negative regulation of cell projection organization

0.65	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
0.43	GO:0031005	filamin binding
0.40	GO:0051219	phosphoprotein binding

0.49	GO:0005737	cytoplasm
0.42	GO:0005813	centrosome
0.41	GO:0030496	midbody
0.40	GO:0005819	spindle
0.40	GO:0031941	filamentous actin
0.40	GO:0030426	growth cone
0.39	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite

0.65

EC:3.5

GO:0016810

sp|Q71SY6|OAF_CHICK
Out at first protein homolog
Search

OAF

0.97	Out at first protein homolog

0.44	GO:0043922	negative regulation by host of viral transcription
0.41	GO:0006366	transcription by RNA polymerase II
0.41	GO:0045944	positive regulation of transcription by RNA polymerase II

0.42	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.42	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0070062	extracellular exosome
0.38	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q71T09|BHE22_CHICK
Class E basic helix-loop-helix protein 22
Search

BHLHE22

0.91	Class E basic helix-loop-helix protein 22

0.67	GO:0030154	cell differentiation
0.64	GO:0048856	anatomical structure development
0.60	GO:0006357	regulation of transcription by RNA polymerase II
0.59	GO:0032501	multicellular organismal process
0.44	GO:0046671	negative regulation of retinal cell programmed cell death
0.41	GO:0120036	plasma membrane bounded cell projection organization
0.40	GO:0045893	positive regulation of transcription, DNA-templated
0.38	GO:0006935	chemotaxis
0.38	GO:0006928	movement of cell or subcellular component
0.37	GO:0006351	transcription, DNA-templated

0.68	GO:0046983	protein dimerization activity
0.60	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.37	GO:0003682	chromatin binding
0.36	GO:0042802	identical protein binding
0.33	GO:0003677	DNA binding

0.38

GO:0005634

nucleus

tr|Q71T10|Q71T10_CHICK
BHLH transcription factor neuroAB
Search

BHLHE23

0.97	BHLH transcription factor neuroAB

0.67	GO:0030154	cell differentiation
0.65	GO:0048856	anatomical structure development
0.55	GO:0006357	regulation of transcription by RNA polymerase II
0.55	GO:0032501	multicellular organismal process
0.50	GO:0046671	negative regulation of retinal cell programmed cell death
0.44	GO:0045893	positive regulation of transcription, DNA-templated
0.40	GO:0120036	plasma membrane bounded cell projection organization
0.38	GO:0006935	chemotaxis
0.38	GO:0006928	movement of cell or subcellular component
0.35	GO:0006351	transcription, DNA-templated

0.68	GO:0046983	protein dimerization activity
0.53	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.35	GO:0003682	chromatin binding
0.34	GO:0042802	identical protein binding
0.33	GO:0003677	DNA binding

0.36

GO:0005634

nucleus

sp|Q75QI0|CFDP1_CHICK
Craniofacial development protein 1
Search

CFDP1

0.96	Craniofacial development protein 1

0.66	GO:0007275	multicellular organism development
0.55	GO:2000270	negative regulation of fibroblast apoptotic process
0.49	GO:0042127	regulation of cell proliferation
0.47	GO:0007155	cell adhesion
0.46	GO:0008360	regulation of cell shape

0.76	GO:0000777	condensed chromosome kinetochore
0.35	GO:0005604	basement membrane

sp|Q75R65|JAK2_CHICK
Tyrosine-protein kinase JAK2
Search

JAK2

0.58	Tyrosine-protein kinase

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.63	GO:0035556	intracellular signal transduction
0.59	GO:0035722	interleukin-12-mediated signaling pathway
0.57	GO:0060396	growth hormone receptor signaling pathway
0.57	GO:0016572	histone phosphorylation
0.56	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.55	GO:0010811	positive regulation of cell-substrate adhesion
0.53	GO:0050727	regulation of inflammatory response
0.50	GO:0030218	erythrocyte differentiation
0.50	GO:0046677	response to antibiotic

0.81	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.75	GO:0042393	histone binding
0.58	GO:0035173	histone kinase activity
0.57	GO:0042169	SH2 domain binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0019901	protein kinase binding
0.51	GO:0005102	receptor binding

0.68	GO:0005856	cytoskeleton
0.54	GO:0005925	focal adhesion
0.48	GO:0005654	nucleoplasm
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.39	GO:0016363	nuclear matrix
0.39	GO:0005737	cytoplasm
0.38	GO:0005901	caveola
0.38	GO:0012505	endomembrane system
0.34	GO:0097708	intracellular vesicle

0.81

GO:0004715

tr|Q75XU5|Q75XU5_CHICK
Neuropeptide FF receptor 1
Search

NPFFR1

0.97	Neuropeptide NPVF receptor

0.78	GO:0007218	neuropeptide signaling pathway
0.64	GO:2000479	regulation of cAMP-dependent protein kinase activity
0.62	GO:0045761	regulation of adenylate cyclase activity
0.58	GO:0043408	regulation of MAPK cascade
0.46	GO:1901652	response to peptide
0.44	GO:0032870	cellular response to hormone stimulus

0.80	GO:0008188	neuropeptide receptor activity
0.65	GO:0031628	opioid receptor binding
0.45	GO:0042277	peptide binding

0.42	GO:0005887	integral component of plasma membrane
0.36	GO:0015629	actin cytoskeleton

tr|Q75XU6|Q75XU6_CHICK
Gonadotropin-inhibitory hormone
Search

NPVF

0.97	Gonadotropin inhibitory hormone peptides

0.80	GO:0007218	neuropeptide signaling pathway
0.48	GO:0032277	negative regulation of gonadotropin secretion
0.41	GO:0046880	regulation of follicle-stimulating hormone secretion
0.41	GO:0032100	positive regulation of appetite
0.41	GO:0033684	regulation of luteinizing hormone secretion

0.39

GO:0001664

G-protein coupled receptor binding

0.39	GO:0043204	perikaryon
0.38	GO:0043005	neuron projection
0.36	GO:0005576	extracellular region

tr|Q766Y2|Q766Y2_CHICK
LIM and SH3 protein
Search

LASP1

0.91	LIM zinc-binding domain-containing Nebulette

0.45	GO:0071691	cardiac muscle thin filament assembly
0.38	GO:0006811	ion transport
0.36	GO:0055085	transmembrane transport
0.35	GO:0009967	positive regulation of signal transduction

0.53	GO:0046872	metal ion binding
0.52	GO:0051015	actin filament binding
0.52	GO:0045296	cadherin binding
0.43	GO:0031005	filamin binding
0.42	GO:0005523	tropomyosin binding
0.37	GO:0015075	ion transmembrane transporter activity
0.36	GO:0005070	SH3/SH2 adaptor activity
0.33	GO:0008307	structural constituent of muscle

0.51	GO:0005925	focal adhesion
0.44	GO:0005856	cytoskeleton
0.42	GO:0005938	cell cortex
0.42	GO:0030018	Z disc
0.39	GO:0070062	extracellular exosome
0.39	GO:0044446	intracellular organelle part

tr|Q76F79|Q76F79_CHICK
Rad9
Search

RAD9A

0.94	G protein-coupled receptor kinase 2

0.81	GO:0000077	DNA damage checkpoint
0.61	GO:0006281	DNA repair
0.60	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.59	GO:0071479	cellular response to ionizing radiation
0.57	GO:0044774	mitotic DNA integrity checkpoint
0.49	GO:0000076	DNA replication checkpoint
0.48	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.36	GO:1901796	regulation of signal transduction by p53 class mediator
0.35	GO:0006310	DNA recombination
0.34	GO:0006260	DNA replication

0.57	GO:0042826	histone deacetylase binding
0.55	GO:0017124	SH3 domain binding
0.54	GO:0019901	protein kinase binding
0.52	GO:0008408	3'-5' exonuclease activity
0.38	GO:0008853	exodeoxyribonuclease III activity

0.84	GO:0030896	checkpoint clamp complex
0.50	GO:0005654	nucleoplasm
0.39	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.38

EC:3.1.11.2

GO:0008853

sp|Q76I89|NDC80_CHICK
Kinetochore protein NDC80 homolog
Search

NDC80

0.92	NDC80 kinetochore complex component

0.86	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint
0.85	GO:0051315	attachment of mitotic spindle microtubules to kinetochore
0.85	GO:1905342	positive regulation of protein localization to kinetochore
0.82	GO:0000132	establishment of mitotic spindle orientation
0.82	GO:0007052	mitotic spindle organization
0.80	GO:0051383	kinetochore organization
0.46	GO:0051301	cell division
0.40	GO:0051311	meiotic metaphase plate congression
0.39	GO:0007143	female meiotic nuclear division
0.38	GO:0051225	spindle assembly

0.71	GO:0042802	identical protein binding
0.59	GO:0005200	structural constituent of cytoskeleton

0.86	GO:0031262	Ndc80 complex
0.80	GO:0000777	condensed chromosome kinetochore
0.79	GO:0000780	condensed nuclear chromosome, centromeric region
0.75	GO:0005813	centrosome
0.68	GO:0005654	nucleoplasm
0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q76I90|NUF2_CHICK
Kinetochore protein Nuf2
Search

NUF2

0.94	Kinetochore protein Nuf2

0.74	GO:0000278	mitotic cell cycle
0.39	GO:0007507	heart development
0.38	GO:0051301	cell division
0.36	GO:0098813	nuclear chromosome segregation
0.34	GO:0051276	chromosome organization

0.35

GO:0005515

protein binding

0.76	GO:0000775	chromosome, centromeric region
0.47	GO:0005634	nucleus
0.46	GO:0043234	protein complex
0.40	GO:0000793	condensed chromosome
0.36	GO:0005815	microtubule organizing center
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q76KB1|HS2ST_CHICK
Heparan sulfate 2-O-sulfotransferase 1
Search

HS2ST1

0.96	Heparan sulfate 2-O-sulfotransferase 1

0.58	GO:0060676	ureteric bud formation
0.58	GO:0030202	heparin metabolic process
0.58	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
0.44	GO:2000047	regulation of cell-cell adhesion mediated by cadherin
0.43	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.42	GO:0060828	regulation of canonical Wnt signaling pathway
0.34	GO:0007424	open tracheal system development
0.34	GO:0006024	glycosaminoglycan biosynthetic process

0.78	GO:0008146	sulfotransferase activity
0.34	GO:0042802	identical protein binding

0.39	GO:0000139	Golgi membrane
0.35	GO:0005759	mitochondrial matrix
0.30	GO:0016021	integral component of membrane

0.78

GO:0008146

sp|Q76KB2|H6ST1_CHICK
Heparan-sulfate 6-O-sulfotransferase 1
Search

HS6ST1

0.75	Heparan-sulfate 6-O-sulfotransferase

0.58	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification
0.50	GO:0048666	neuron development
0.48	GO:0048286	lung alveolus development
0.47	GO:0001525	angiogenesis
0.46	GO:0060716	labyrinthine layer blood vessel development
0.37	GO:0048048	embryonic eye morphogenesis
0.37	GO:0048754	branching morphogenesis of an epithelial tube
0.36	GO:0060173	limb development
0.34	GO:0006024	glycosaminoglycan biosynthetic process
0.33	GO:0006635	fatty acid beta-oxidation

0.78	GO:0008146	sulfotransferase activity
0.35	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding
0.34	GO:0070492	oligosaccharide binding
0.34	GO:0003997	acyl-CoA oxidase activity
0.33	GO:0071949	FAD binding

0.35	GO:0005654	nucleoplasm
0.34	GO:0000139	Golgi membrane
0.33	GO:0005887	integral component of plasma membrane
0.33	GO:0042579	microbody

0.78

GO:0008146

sp|Q76LT9|TM258_CHICK
Transmembrane protein 258
Search

TMEM258

0.59	Transmembrane domain-containing protein (Fragment)

0.80	GO:0006487	protein N-linked glycosylation
0.36	GO:0015031	protein transport

0.85	GO:0034998	oligosaccharyltransferase I complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q76LW2|H6ST2_CHICK
Heparan-sulfate 6-O-sulfotransferase 2
Search

0.73	Heparan-sulfate 6-O-sulfotransferase

0.56	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification
0.48	GO:0001525	angiogenesis
0.47	GO:0035295	tube development
0.46	GO:0048666	neuron development
0.46	GO:0048568	embryonic organ development
0.43	GO:0060541	respiratory system development
0.43	GO:0061138	morphogenesis of a branching epithelium
0.42	GO:0060674	placenta blood vessel development
0.42	GO:0048592	eye morphogenesis
0.41	GO:0048598	embryonic morphogenesis

0.78	GO:0008146	sulfotransferase activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005654	nucleoplasm
0.36	GO:0000139	Golgi membrane
0.35	GO:0070062	extracellular exosome
0.33	GO:0005887	integral component of plasma membrane

0.78

GO:0008146

sp|Q76MS9|MSTN1_CHICK
Musculoskeletal embryonic nuclear protein 1
Search

MUSTN1

0.97	Musculoskeletal embryonic nuclear protein 1

0.86	GO:0035988	chondrocyte proliferation
0.85	GO:0002062	chondrocyte differentiation
0.85	GO:0042246	tissue regeneration
0.47	GO:1902730	positive regulation of proteoglycan biosynthetic process
0.47	GO:1902732	positive regulation of chondrocyte proliferation
0.46	GO:0032332	positive regulation of chondrocyte differentiation
0.42	GO:0010628	positive regulation of gene expression
0.38	GO:0030326	embryonic limb morphogenesis

0.61	GO:0005634	nucleus
0.36	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part

tr|Q789A4|Q789A4_CHICK
Nonmuscle myosin heavy chain
Search

MYH10

0.91	Nonmuscle myosin heavy chain b

0.66	GO:0007018	microtubule-based movement
0.52	GO:0031032	actomyosin structure organization
0.51	GO:0000281	mitotic cytokinesis
0.49	GO:0030048	actin filament-based movement
0.48	GO:0050714	positive regulation of protein secretion
0.46	GO:0021592	fourth ventricle development
0.46	GO:0021678	third ventricle development
0.46	GO:0006930	substrate-dependent cell migration, cell extension
0.46	GO:0001778	plasma membrane repair
0.46	GO:0021670	lateral ventricle development

0.74	GO:0003779	actin binding
0.73	GO:0003774	motor activity
0.71	GO:0032403	protein complex binding
0.66	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0030898	actin-dependent ATPase activity
0.50	GO:0035613	RNA stem-loop binding
0.48	GO:0048027	mRNA 5'-UTR binding

0.77	GO:0016459	myosin complex
0.53	GO:0097517	contractile actin filament bundle
0.53	GO:0042641	actomyosin
0.49	GO:0005938	cell cortex
0.49	GO:0032154	cleavage furrow
0.48	GO:0030496	midbody
0.48	GO:0005844	polysome
0.44	GO:0043197	dendritic spine
0.44	GO:0031594	neuromuscular junction
0.44	GO:0030426	growth cone

sp|Q789F3|MAF_CHICK
Transcription factor Maf
Search

0.90	V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba

0.57	GO:0070306	lens fiber cell differentiation
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.55	GO:0006351	transcription, DNA-templated
0.54	GO:0032330	regulation of chondrocyte differentiation
0.53	GO:0001816	cytokine production
0.52	GO:0048839	inner ear development
0.51	GO:1902680	positive regulation of RNA biosynthetic process
0.49	GO:0048468	cell development

0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0003677	DNA binding
0.40	GO:0001067	regulatory region nucleic acid binding
0.38	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.36	GO:0000785	chromatin
0.35	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

tr|Q7LZ70|Q7LZ70_CHICK
Gamma-aminobutyric acid A receptor gamma 1 chain
Search

GABRG1

0.96	Gamma-aminobutyric acid A receptor gamma 1 chain

0.85	GO:0007214	gamma-aminobutyric acid signaling pathway
0.77	GO:0006821	chloride transport
0.60	GO:0034220	ion transmembrane transport
0.56	GO:0007268	chemical synaptic transmission
0.52	GO:0071420	cellular response to histamine
0.49	GO:0030534	adult behavior
0.47	GO:0009791	post-embryonic development

0.84	GO:0004890	GABA-A receptor activity
0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.48	GO:0005254	chloride channel activity
0.38	GO:0050811	GABA receptor binding
0.35	GO:0008503	benzodiazepine receptor activity

0.55	GO:0005886	plasma membrane
0.51	GO:1902711	GABA-A receptor complex
0.48	GO:0030424	axon
0.41	GO:0034707	chloride channel complex
0.40	GO:0098794	postsynapse
0.40	GO:0030054	cell junction
0.38	GO:0030425	dendrite
0.38	GO:0030659	cytoplasmic vesicle membrane
0.36	GO:0060077	inhibitory synapse
0.35	GO:0031252	cell leading edge

sp|Q7LZR2|CO8A1_CHICK
Collagen alpha-1(VIII) chain
Search

COL8A1

0.92	Collagen type VIII alpha 1 chain

0.61	GO:0050673	epithelial cell proliferation
0.60	GO:0048593	camera-type eye morphogenesis
0.57	GO:0035987	endodermal cell differentiation
0.53	GO:0010811	positive regulation of cell-substrate adhesion
0.41	GO:0001525	angiogenesis
0.39	GO:0007155	cell adhesion
0.36	GO:0030574	collagen catabolic process
0.36	GO:0030198	extracellular matrix organization
0.35	GO:0014028	notochord formation
0.34	GO:0060322	head development

0.34	GO:0005201	extracellular matrix structural constituent
0.34	GO:0030674	protein binding, bridging

0.75	GO:0005581	collagen trimer
0.63	GO:0005576	extracellular region
0.37	GO:0005938	cell cortex
0.36	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0031982	vesicle
0.34	GO:0099081	supramolecular polymer
0.30	GO:0016020	membrane

tr|Q7SX63|Q7SX63_CHICK
Heat shock protein 70
Search

HSPA2

0.61	Inducible heat shock protein 70

0.65	GO:0009409	response to cold
0.61	GO:0009408	response to heat
0.56	GO:0031662	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle
0.56	GO:1901896	positive regulation of calcium-transporting ATPase activity
0.55	GO:0070194	synaptonemal complex disassembly
0.54	GO:0090084	negative regulation of inclusion body assembly
0.54	GO:0007141	male meiosis I
0.51	GO:0007286	spermatid development
0.48	GO:0042026	protein refolding
0.40	GO:0032570	response to progesterone

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0051861	glycolipid binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.53	GO:0097718	disordered domain specific binding
0.47	GO:0019899	enzyme binding
0.46	GO:0051082	unfolded protein binding
0.41	GO:0033142	progesterone receptor binding
0.35	GO:0055131	C3HC4-type RING finger domain binding

0.54	GO:0036128	CatSper complex
0.54	GO:0072687	meiotic spindle
0.54	GO:0001673	male germ cell nucleus
0.52	GO:0000795	synaptonemal complex
0.51	GO:0043209	myelin sheath
0.48	GO:0009986	cell surface
0.46	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.39	GO:0043204	perikaryon
0.38	GO:0043235	receptor complex

0.33

GO:0016887

tr|Q7SX83|Q7SX83_CHICK
CAMP response element-binding protein
Search

CREB1

0.85	cAMP responsive element binding protein 1

0.63	GO:0060509	Type I pneumocyte differentiation
0.63	GO:0060430	lung saccule development
0.63	GO:0010944	negative regulation of transcription by competitive promoter binding
0.63	GO:0071294	cellular response to zinc ion
0.62	GO:0035729	cellular response to hepatocyte growth factor stimulus
0.62	GO:0033762	response to glucagon
0.61	GO:0045672	positive regulation of osteoclast differentiation
0.61	GO:0033363	secretory granule organization
0.61	GO:0021983	pituitary gland development
0.61	GO:0055025	positive regulation of cardiac muscle tissue development

0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.60	GO:0035497	cAMP response element binding
0.60	GO:0001102	RNA polymerase II activating transcription factor binding
0.60	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.53	GO:0042802	identical protein binding
0.53	GO:0019899	enzyme binding
0.41	GO:0001225	RNA polymerase II transcription coactivator binding
0.40	GO:1990763	arrestin family protein binding
0.39	GO:0030544	Hsp70 protein binding

0.65	GO:1990589	ATF4-CREB1 transcription factor complex
0.60	GO:0005719	nuclear euchromatin
0.52	GO:0005654	nucleoplasm
0.38	GO:0030424	axon
0.37	GO:0005759	mitochondrial matrix

sp|Q7SZC6|RGS4_CHICK
Regulator of G-protein signaling 4
Search

RGS4

0.97	LOW QUALITY PROTEIN: regulator of G-protein signaling 4

0.73	GO:0043547	positive regulation of GTPase activity
0.68	GO:0007186	G-protein coupled receptor signaling pathway
0.43	GO:0031018	endocrine pancreas development
0.42	GO:0009968	negative regulation of signal transduction
0.42	GO:0007626	locomotory behavior
0.41	GO:0007409	axonogenesis
0.41	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.36	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.35	GO:0043405	regulation of MAP kinase activity
0.34	GO:0010519	negative regulation of phospholipase activity

0.74	GO:0005096	GTPase activator activity
0.40	GO:0001965	G-protein alpha-subunit binding
0.34	GO:0005516	calmodulin binding

0.45	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.39	GO:0005886	plasma membrane
0.34	GO:0043234	protein complex
0.34	GO:0098562	cytoplasmic side of membrane
0.33	GO:0019898	extrinsic component of membrane

sp|Q7SZI5|RFTN1_CHICK
Raftlin
Search

RFTN1

0.97	Raftlin lipid raft linker 1

0.80	GO:0050851	antigen receptor-mediated signaling pathway
0.80	GO:0034138	toll-like receptor 3 signaling pathway
0.79	GO:0033227	dsRNA transport
0.79	GO:0043330	response to exogenous dsRNA
0.79	GO:0001765	membrane raft assembly
0.76	GO:0032596	protein transport into membrane raft
0.71	GO:0040007	growth
0.67	GO:0002457	T cell antigen processing and presentation
0.66	GO:0032620	interleukin-17 production
0.34	GO:0007281	germ cell development

0.70	GO:0003725	double-stranded RNA binding
0.45	GO:0003730	mRNA 3'-UTR binding
0.34	GO:0008494	translation activator activity

0.77	GO:0045121	membrane raft
0.69	GO:0005768	endosome
0.55	GO:0043234	protein complex
0.53	GO:0005886	plasma membrane
0.43	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

tr|Q7T048|Q7T048_CHICK
Aryl-hydrocarbon receptor-interacting protein
Search

AIP

0.81	AH receptor-interacting protein isoform 1

0.81	GO:0022417	protein maturation by protein folding
0.74	GO:0006805	xenobiotic metabolic process
0.73	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity
0.70	GO:0006626	protein targeting to mitochondrion
0.66	GO:0010738	regulation of protein kinase A signaling
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:0035722	interleukin-12-mediated signaling pathway

0.84	GO:0036004	GAF domain binding
0.82	GO:0017162	aryl hydrocarbon receptor binding
0.73	GO:0003712	transcription cofactor activity
0.64	GO:0051082	unfolded protein binding
0.43	GO:0004871	signal transducer activity

0.79	GO:0034751	aryl hydrocarbon receptor complex
0.63	GO:0005829	cytosol
0.51	GO:0005886	plasma membrane
0.45	GO:0005654	nucleoplasm

sp|Q7T0B1|STK40_CHICK
Serine/threonine-protein kinase 40
Search

STK40

0.97	Serine/threonine-protein kinase 40

0.61	GO:0006468	protein phosphorylation
0.57	GO:0003016	respiratory system process
0.56	GO:0048286	lung alveolus development
0.55	GO:0060425	lung morphogenesis
0.54	GO:0035264	multicellular organism growth
0.51	GO:0043408	regulation of MAPK cascade
0.51	GO:0043066	negative regulation of apoptotic process
0.50	GO:0005977	glycogen metabolic process
0.42	GO:0010468	regulation of gene expression

0.62	GO:0004672	protein kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.47	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q7T0L4|TE2IP_CHICK
Telomeric repeat-binding factor 2-interacting protein 1
Search

TERF2IP

0.70	Telomeric repeat-binding factor 2-interacting protein 1

0.72	GO:0048239	negative regulation of DNA recombination at telomere
0.70	GO:0031848	protection from non-homologous end joining at telomere
0.68	GO:0010569	regulation of double-strand break repair via homologous recombination
0.67	GO:0010833	telomere maintenance via telomere lengthening
0.65	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.65	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.62	GO:0070198	protein localization to chromosome, telomeric region
0.61	GO:0032205	negative regulation of telomere maintenance
0.61	GO:1901224	positive regulation of NIK/NF-kappaB signaling
0.61	GO:1901985	positive regulation of protein acetylation

0.63	GO:0098505	G-rich strand telomeric DNA binding
0.59	GO:0019902	phosphatase binding

0.63	GO:0000781	chromosome, telomeric region
0.59	GO:0030870	Mre11 complex
0.57	GO:0005654	nucleoplasm
0.54	GO:0044454	nuclear chromosome part
0.53	GO:0005635	nuclear envelope
0.53	GO:0032993	protein-DNA complex
0.51	GO:0005829	cytosol

sp|Q7T199|KCA10_CHICK
Potassium voltage-gated channel subfamily A member 10
Search

KCNA10

0.97	Potassium voltage-gated channel subfamily A member 10

0.78	GO:0051260	protein homooligomerization
0.77	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.35	GO:0071286	cellular response to magnesium ion
0.35	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain
0.34	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch
0.34	GO:0010960	magnesium ion homeostasis
0.34	GO:0001964	startle response
0.34	GO:0019228	neuronal action potential
0.34	GO:0007405	neuroblast proliferation

0.78	GO:0005249	voltage-gated potassium channel activity
0.35	GO:0005221	intracellular cyclic nucleotide activated cation channel activity
0.34	GO:0097718	disordered domain specific binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.35	GO:0030424	axon
0.34	GO:0043679	axon terminus
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite
0.33	GO:0009986	cell surface
0.33	GO:0030054	cell junction

tr|Q7T1A0|Q7T1A0_CHICK
Shaker subfamily potassium channel Kv1.2 alpha subunit
Search

KCNA2

0.97	Potassium voltage-gated channel subfamily A member 2

0.77	GO:0051260	protein homooligomerization
0.77	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.57	GO:0021633	optic nerve structural organization
0.56	GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep
0.55	GO:0014059	regulation of dopamine secretion
0.50	GO:0019228	neuronal action potential
0.48	GO:0019233	sensory perception of pain
0.48	GO:0071286	cellular response to magnesium ion
0.47	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch

0.78	GO:0005249	voltage-gated potassium channel activity
0.46	GO:0097718	disordered domain specific binding
0.38	GO:0019894	kinesin binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.62	GO:0044224	juxtaparanode region of axon
0.58	GO:0043679	axon terminus
0.56	GO:0043025	neuronal cell body
0.56	GO:0030425	dendrite
0.55	GO:0044298	cell body membrane
0.47	GO:0033270	paranode region of axon
0.45	GO:0030054	cell junction
0.43	GO:0009986	cell surface
0.42	GO:0042734	presynaptic membrane

sp|Q7T2H2|FGRL1_CHICK
Fibroblast growth factor receptor-like 1
Search

FGFRL1

0.96	Fibroblast growth factor receptor like 1

0.52	GO:0001501	skeletal system development
0.52	GO:0008543	fibroblast growth factor receptor signaling pathway
0.52	GO:0060412	ventricular septum morphogenesis
0.51	GO:0003179	heart valve morphogenesis
0.50	GO:0060539	diaphragm development
0.49	GO:0051260	protein homooligomerization
0.49	GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules
0.49	GO:0008285	negative regulation of cell proliferation
0.43	GO:0021592	fourth ventricle development
0.43	GO:0021678	third ventricle development

0.54	GO:0005007	fibroblast growth factor-activated receptor activity
0.52	GO:0008201	heparin binding
0.51	GO:0017134	fibroblast growth factor binding
0.36	GO:0001571	non-tyrosine kinase fibroblast growth factor receptor activity

0.52	GO:0044291	cell-cell contact zone
0.49	GO:0030133	transport vesicle
0.47	GO:0005794	Golgi apparatus
0.41	GO:0005886	plasma membrane
0.34	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.33	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

sp|Q7T2L7|I17RD_CHICK
Interleukin-17 receptor D
Search

IL17RD

0.97	Interleukin-17 receptor D

0.60	GO:0019221	cytokine-mediated signaling pathway
0.39	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway
0.39	GO:0000165	MAPK cascade
0.38	GO:0000188	inactivation of MAPK activity
0.38	GO:0009953	dorsal/ventral pattern formation

0.68	GO:0030368	interleukin-17 receptor activity
0.35	GO:0003676	nucleic acid binding

0.68	GO:0005794	Golgi apparatus
0.67	GO:0005654	nucleoplasm
0.52	GO:0005887	integral component of plasma membrane
0.40	GO:0098588	bounding membrane of organelle
0.39	GO:0031984	organelle subcompartment

sp|Q7T2T1|CELF2_CHICK
CUGBP Elav-like family member 2
Search

CELF2

0.93	cDNA FLJ50655, highly similar to Homo sapiens CUG triplet repeat, RNA binding protein 2 (CUGBP2), transcript variant 3, mRNA

0.50	GO:0006376	mRNA splice site selection
0.35	GO:0000380	alternative mRNA splicing, via spliceosome
0.34	GO:0008016	regulation of heart contraction
0.34	GO:0017148	negative regulation of translation

0.59	GO:0003723	RNA binding
0.35	GO:0000900	translation repressor activity, nucleic acid binding
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.43	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.33	GO:0019013	viral nucleocapsid
0.32	GO:0030529	intracellular ribonucleoprotein complex

sp|Q7T2U9|TFCP2_CHICK
Transcription factor CP2
Search

TFCP2

0.77	Transcription factor LSF

0.70	GO:0006366	transcription by RNA polymerase II
0.69	GO:0045944	positive regulation of transcription by RNA polymerase II
0.55	GO:0009299	mRNA transcription
0.38	GO:0002070	epithelial cell maturation
0.38	GO:0007028	cytoplasm organization
0.37	GO:0007431	salivary gland development
0.37	GO:0008340	determination of adult lifespan
0.37	GO:0045927	positive regulation of growth
0.36	GO:0009653	anatomical structure morphogenesis
0.36	GO:0000122	negative regulation of transcription by RNA polymerase II

0.75	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.49	GO:0008134	transcription factor binding
0.39	GO:0008022	protein C-terminus binding

0.48	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.43	GO:0043234	protein complex
0.37	GO:0001650	fibrillar center
0.34	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

sp|Q7T2Z5|UNC5C_CHICK
Netrin receptor UNC5C
Search

UNC5C

0.92	Unc-5 netrin receptor C

0.85	GO:0038007	netrin-activated signaling pathway
0.57	GO:0033564	anterior/posterior axon guidance
0.52	GO:0007420	brain development
0.52	GO:0030334	regulation of cell migration
0.52	GO:0043065	positive regulation of apoptotic process
0.38	GO:0006915	apoptotic process

0.85

GO:0005042

netrin receptor activity

0.42	GO:0005886	plasma membrane
0.39	GO:0043005	neuron projection
0.38	GO:0045202	synapse
0.38	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

sp|Q7T3T4|SMS1_CHICK
Phosphatidylcholine:ceramide cholinephosphotransferase 1
Search

SGMS1

0.69	Phosphatidylcholine:ceramide cholinephosphotransferase 1

0.60	GO:0046513	ceramide biosynthetic process
0.54	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.54	GO:0006686	sphingomyelin biosynthetic process
0.43	GO:1905371	ceramide phosphoethanolamine metabolic process
0.39	GO:0006915	apoptotic process
0.38	GO:0006954	inflammatory response
0.38	GO:0071356	cellular response to tumor necrosis factor
0.38	GO:0071222	cellular response to lipopolysaccharide
0.36	GO:0010628	positive regulation of gene expression
0.36	GO:0016310	phosphorylation

0.63	GO:0033188	sphingomyelin synthase activity
0.61	GO:0002950	ceramide phosphoethanolamine synthase activity
0.54	GO:0047493	ceramide cholinephosphotransferase activity
0.36	GO:0016301	kinase activity

0.50	GO:0030173	integral component of Golgi membrane
0.47	GO:0030176	integral component of endoplasmic reticulum membrane
0.44	GO:0005887	integral component of plasma membrane
0.38	GO:0000138	Golgi trans cisterna
0.34	GO:0005634	nucleus

0.63	EC:2.7.8.27	GO:0033188
0.63	KEGG:R08969	GO:0033188

sp|Q7ZT11|ANKR1_CHICK
Ankyrin repeat domain-containing protein 1
Search

ANKRD1

0.97	Ankyrin repeat domain-containing protein 1

0.84	GO:0035914	skeletal muscle cell differentiation
0.82	GO:1901796	regulation of signal transduction by p53 class mediator
0.77	GO:0035994	response to muscle stretch
0.75	GO:0071260	cellular response to mechanical stimulus
0.74	GO:2000279	negative regulation of DNA biosynthetic process
0.74	GO:0055008	cardiac muscle tissue morphogenesis
0.74	GO:0071347	cellular response to interleukin-1
0.73	GO:2001022	positive regulation of response to DNA damage stimulus
0.73	GO:0071356	cellular response to tumor necrosis factor
0.72	GO:0071222	cellular response to lipopolysaccharide

0.86	GO:0031432	titin binding
0.82	GO:0001085	RNA polymerase II transcription factor binding
0.77	GO:0070412	R-SMAD binding
0.74	GO:0001105	RNA polymerase II transcription coactivator activity
0.74	GO:0002039	p53 binding
0.73	GO:0042826	histone deacetylase binding
0.70	GO:0003714	transcription corepressor activity
0.60	GO:0043422	protein kinase B binding
0.52	GO:0003682	chromatin binding
0.50	GO:0003677	DNA binding

0.81	GO:0031674	I band
0.72	GO:0001650	fibrillar center
0.65	GO:0005829	cytosol
0.65	GO:0005667	transcription factor complex
0.56	GO:0000791	euchromatin
0.56	GO:0016605	PML body
0.37	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016020	membrane

tr|Q7ZT27|Q7ZT27_CHICK
p15INK4b tumor suppressor
Search

0.95	Cyclin dependant kinase inhibitor

0.67	GO:0007050	cell cycle arrest
0.66	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.66	GO:0044772	mitotic cell cycle phase transition
0.65	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
0.65	GO:1904030	negative regulation of cyclin-dependent protein kinase activity
0.64	GO:0008285	negative regulation of cell proliferation
0.62	GO:0030308	negative regulation of cell growth
0.62	GO:0044843	cell cycle G1/S phase transition
0.52	GO:0048536	spleen development
0.52	GO:2000045	regulation of G1/S transition of mitotic cell cycle

0.68	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.63	GO:0019901	protein kinase binding
0.52	GO:0016301	kinase activity
0.49	GO:0051059	NF-kappaB binding
0.40	GO:1990948	ubiquitin ligase inhibitor activity
0.40	GO:0097371	MDM2/MDM4 family protein binding
0.39	GO:0097718	disordered domain specific binding
0.39	GO:0047485	protein N-terminus binding
0.39	GO:0002039	p53 binding
0.38	GO:0019789	SUMO transferase activity

0.51	GO:0005634	nucleus
0.51	GO:0035985	senescence-associated heterochromatin focus
0.43	GO:0005737	cytoplasm
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0043234	protein complex
0.33	GO:1905369	endopeptidase complex

0.33

EC:2.3.1

GO:0016747

tr|Q7ZT63|Q7ZT63_CHICK
Proteasome subunit beta type
Search

PSMB7

0.53	Proteasome subunit beta type

0.71	GO:0051603	proteolysis involved in cellular protein catabolic process
0.55	GO:1903955	positive regulation of protein targeting to mitochondrion
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0043312	neutrophil degranulation

0.76	GO:0004298	threonine-type endopeptidase activity
0.33	GO:0005515	protein binding
0.33	GO:0016301	kinase activity

0.75	GO:0005839	proteasome core complex
0.57	GO:0005634	nucleus
0.48	GO:0005829	cytosol
0.47	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.35	GO:0101002	ficolin-1-rich granule
0.35	GO:0031983	vesicle lumen
0.30	GO:0016020	membrane

0.76

EC:3.4.25

GO:0004298

tr|Q7ZTG3|Q7ZTG3_CHICK
ARF tumor suppressor
Search

0.94	ARF tumor suppressor

sp|Q7ZUA6|LMBR1_CHICK
Limb region 1 protein homolog
Search

LMBR1

0.97	Limb development membrane protein 1

0.55	GO:0042733	embryonic digit morphogenesis
0.35	GO:0035116	embryonic hindlimb morphogenesis
0.33	GO:0006898	receptor-mediated endocytosis

0.33

GO:0060089

molecular transducer activity

0.33

GO:0005887

integral component of plasma membrane

sp|Q7ZZL8|TMHS_CHICK
Tetraspan membrane protein of hair cell stereocilia homolog
Search

LHFPL5

0.96	Tetraspan membrane protein of hair cell stereocilia

0.57	GO:0060088	auditory receptor cell stereocilium organization
0.57	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
0.35	GO:0006811	ion transport

0.34

GO:0005515

protein binding

0.57	GO:0032426	stereocilium tip
0.54	GO:0016324	apical plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q7ZZN4|Q7ZZN4_CHICK
Fibroblast growth factor
Search

FGF9

0.62	Fibroblast growth factor

0.83	GO:0008543	fibroblast growth factor receptor signaling pathway
0.75	GO:0010469	regulation of receptor activity
0.60	GO:0060043	regulation of cardiac muscle cell proliferation
0.58	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.57	GO:0048839	inner ear development
0.56	GO:0060484	lung-associated mesenchyme development
0.56	GO:0032927	positive regulation of activin receptor signaling pathway
0.56	GO:0008584	male gonad development
0.56	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
0.56	GO:0048505	regulation of timing of cell differentiation

0.85	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.50	GO:0090722	receptor-receptor interaction
0.41	GO:0008201	heparin binding
0.37	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0004713	protein tyrosine kinase activity
0.34	GO:0043395	heparan sulfate proteoglycan binding

0.66	GO:0005576	extracellular region
0.38	GO:0031982	vesicle
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.37	EC:2.7.1.153	GO:0046934
0.37	KEGG:R04545	GO:0046934

sp|Q7ZZR3|BRNP1_CHICK
BMP/retinoic acid-inducible neural-specific protein 1
Search

BRINP1

0.97	Bone morphogenetic protein/retinoic acid inducible neural-specific 1

0.82	GO:0045666	positive regulation of neuron differentiation
0.79	GO:0045930	negative regulation of mitotic cell cycle
0.60	GO:0071300	cellular response to retinoic acid
0.58	GO:0042711	maternal behavior
0.58	GO:0071625	vocalization behavior
0.57	GO:0007614	short-term memory
0.57	GO:0035640	exploration behavior
0.57	GO:0001662	behavioral fear response
0.56	GO:0035176	social behavior
0.54	GO:0050768	negative regulation of neurogenesis

0.33

GO:0005515

protein binding

0.48	GO:0043025	neuronal cell body
0.48	GO:0030425	dendrite
0.44	GO:0005783	endoplasmic reticulum
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|Q7ZZS5|Q7ZZS5_CHICK
Regulator of G-protein signaling protein 2 long isoform
Search

RGS2

0.97	Regulator of G-protein signaling protein 2

0.77	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway
0.72	GO:0043547	positive regulation of GTPase activity
0.58	GO:0010519	negative regulation of phospholipase activity
0.58	GO:0071877	regulation of adrenergic receptor signaling pathway
0.58	GO:0060087	relaxation of vascular smooth muscle
0.58	GO:0060452	positive regulation of cardiac muscle contraction
0.58	GO:0055119	relaxation of cardiac muscle
0.57	GO:0010614	negative regulation of cardiac muscle hypertrophy
0.57	GO:0043951	negative regulation of cAMP-mediated signaling
0.54	GO:0043407	negative regulation of MAP kinase activity

0.72	GO:0005096	GTPase activator activity
0.58	GO:0001965	G-protein alpha-subunit binding
0.38	GO:0048487	beta-tubulin binding
0.34	GO:0005516	calmodulin binding

0.51	GO:0009898	cytoplasmic side of plasma membrane
0.49	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.37	GO:0043005	neuron projection
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0044446	intracellular organelle part
0.33	GO:0019897	extrinsic component of plasma membrane
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

tr|Q7ZZY2|Q7ZZY2_CHICK
TRB2 protein
Search

TRIB2

0.40	Serine/threonine protein kinase

0.63	GO:0006468	protein phosphorylation
0.60	GO:0045081	negative regulation of interleukin-10 biosynthetic process
0.58	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.55	GO:0045599	negative regulation of fat cell differentiation
0.50	GO:0050790	regulation of catalytic activity
0.49	GO:0043408	regulation of MAPK cascade
0.46	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway
0.45	GO:0045643	regulation of eosinophil differentiation
0.45	GO:0014912	negative regulation of smooth muscle cell migration
0.45	GO:0045659	negative regulation of neutrophil differentiation

0.64	GO:0004672	protein kinase activity
0.56	GO:0055106	ubiquitin-protein transferase regulator activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.54	GO:0031434	mitogen-activated protein kinase kinase binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0008134	transcription factor binding
0.46	GO:0004860	protein kinase inhibitor activity

0.42	GO:0005634	nucleus
0.37	GO:0005856	cytoskeleton
0.36	GO:0005737	cytoplasm

tr|Q800I0|Q800I0_CHICK
CD30 protein
Search

TNFRSF8

0.95	Tumor necrosis factor receptor superfamily member 8

0.45	GO:0045556	positive regulation of TRAIL biosynthetic process
0.44	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process
0.42	GO:0071260	cellular response to mechanical stimulus
0.42	GO:0007165	signal transduction
0.41	GO:0043065	positive regulation of apoptotic process
0.41	GO:0006915	apoptotic process
0.40	GO:0071356	cellular response to tumor necrosis factor
0.39	GO:0006954	inflammatory response
0.38	GO:0051093	negative regulation of developmental process
0.38	GO:0051241	negative regulation of multicellular organismal process

0.44	GO:0004888	transmembrane signaling receptor activity
0.39	GO:0048406	nerve growth factor binding

0.37	GO:0043005	neuron projection
0.37	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:0005887	integral component of plasma membrane
0.35	GO:0005578	proteinaceous extracellular matrix
0.35	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm

sp|Q800K9|SURF4_CHICK
Surfeit locus protein 4
Search

SURF4

0.96	Surfeit gene 4

0.49	GO:0007030	Golgi organization
0.47	GO:0010638	positive regulation of organelle organization
0.38	GO:0034498	early endosome to Golgi transport
0.38	GO:0032527	protein exit from endoplasmic reticulum
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER

0.34

GO:0005515

protein binding

0.51	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.39	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0000139	Golgi membrane
0.35	GO:0035577	azurophil granule membrane
0.34	GO:0030133	transport vesicle
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q800L1|SURF1_CHICK
Surfeit locus protein 1
Search

0.48	GO:0033617	mitochondrial respiratory chain complex IV assembly
0.44	GO:0021522	spinal cord motor neuron differentiation
0.43	GO:1902600	hydrogen ion transmembrane transport
0.43	GO:0006754	ATP biosynthetic process
0.42	GO:0048568	embryonic organ development
0.42	GO:0022900	electron transport chain
0.41	GO:0006119	oxidative phosphorylation
0.35	GO:0042331	phototaxis
0.35	GO:0002168	instar larval development
0.35	GO:0007632	visual behavior

0.44	GO:0015002	heme-copper terminal oxidase activity
0.44	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.43	GO:0015078	hydrogen ion transmembrane transporter activity
0.43	GO:0009055	electron transfer activity
0.33	GO:0005515	protein binding
0.33	GO:0016934	extracellularly glycine-gated chloride channel activity
0.32	GO:0004888	transmembrane signaling receptor activity

0.60	GO:0031966	mitochondrial membrane
0.60	GO:0019866	organelle inner membrane
0.35	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.33	GO:0070469	respiratory chain
0.32	GO:0045211	postsynaptic membrane
0.30	GO:0016021	integral component of membrane

0.44

EC:1.9.3

GO:0016676

sp|Q800L3|MED22_CHICK
Mediator of RNA polymerase II transcription subunit 22
Search

MED22

0.90	Mediator of RNA polymerase II transcription subunit 22

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0006351	transcription, DNA-templated
0.33	GO:0005975	carbohydrate metabolic process

0.79	GO:0001104	RNA polymerase II transcription cofactor activity
0.33	GO:0016758	transferase activity, transferring hexosyl groups
0.33	GO:0005515	protein binding

0.77	GO:0016592	mediator complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33

GO:0016758

sp|Q801X6|PHAR1_CHICK
Phosphatase and actin regulator 1
Search

PHACTR1

0.76	Phosphatase and actin regulator

0.83	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.77	GO:0031532	actin cytoskeleton reorganization
0.58	GO:0043149	stress fiber assembly
0.48	GO:0048870	cell motility
0.34	GO:0042325	regulation of phosphorylation
0.33	GO:0001944	vasculature development
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.85	GO:0008157	protein phosphatase 1 binding
0.83	GO:0004864	protein phosphatase inhibitor activity
0.74	GO:0003779	actin binding
0.32	GO:0003676	nucleic acid binding

0.47	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.39	GO:0045202	synapse
0.38	GO:0030054	cell junction

sp|Q802A9|FGFP2_CHICK
Fibroblast growth factor-binding protein 2
Search

FGFBP2

0.97	Fibroblast growth factor-binding protein 2

0.82

GO:0019838

growth factor binding

0.73

GO:0005615

extracellular space

tr|Q802E3|Q802E3_CHICK
Phosphodiesterase 6 gamma subunit cone form
Search

PDE6H

0.95	Cone phosphodiesterase beta subunit

0.75	GO:0007601	visual perception
0.51	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
0.50	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
0.49	GO:0000187	activation of MAPK activity
0.38	GO:0050896	response to stimulus
0.35	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.35	GO:0043086	negative regulation of catalytic activity
0.34	GO:0198738	cell-cell signaling by wnt

0.84	GO:0030553	cGMP binding
0.76	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.38	GO:0030507	spectrin binding
0.36	GO:0004857	enzyme inhibitor activity
0.33	GO:0008270	zinc ion binding

0.38	GO:0097381	photoreceptor disc membrane
0.35	GO:0042622	photoreceptor outer segment membrane

0.76

EC:3.1.4.17

GO:0004114

tr|Q802E4|Q802E4_CHICK
Phosphodiesterase 6 gamma subunit rod form
Search

PDE6G

0.97	Retinal rod rhodopsin-sensitive cgmp 3'5'-cyclic phosphodiesterase subunit gamma

0.76	GO:0007601	visual perception
0.51	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
0.51	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
0.49	GO:0000187	activation of MAPK activity
0.38	GO:0050896	response to stimulus
0.36	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.35	GO:0043086	negative regulation of catalytic activity
0.35	GO:0198738	cell-cell signaling by wnt

0.85	GO:0030553	cGMP binding
0.77	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.39	GO:0030507	spectrin binding
0.36	GO:0004857	enzyme inhibitor activity
0.33	GO:0008270	zinc ion binding

0.38	GO:0097381	photoreceptor disc membrane
0.36	GO:0042622	photoreceptor outer segment membrane

0.77

EC:3.1.4.17

GO:0004114

tr|Q802E6|Q802E6_CHICK
Bombesin-like peptide receptor subtype 3.5
Search

BRS3

0.94	Gastrin releasing peptide receptor

0.79	GO:0031989	bombesin receptor signaling pathway
0.52	GO:0036343	psychomotor behavior
0.50	GO:0035176	social behavior
0.50	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.48	GO:0007218	neuropeptide signaling pathway
0.46	GO:0042127	regulation of cell proliferation
0.44	GO:0043207	response to external biotic stimulus
0.35	GO:0008343	adult feeding behavior
0.34	GO:0003008	system process
0.34	GO:0008283	cell proliferation

0.79	GO:0004946	bombesin receptor activity
0.34	GO:0042923	neuropeptide binding
0.32	GO:0005515	protein binding
0.32	GO:0003723	RNA binding

0.44	GO:0005887	integral component of plasma membrane
0.41	GO:0005829	cytosol
0.37	GO:0043025	neuronal cell body
0.36	GO:0043005	neuron projection

tr|Q802T0|Q802T0_CHICK
MIZIP protein
Search

ZMYND19

0.95	Melanin-concentrating hormone receptor 1

0.36	GO:0043043	peptide biosynthetic process
0.35	GO:0044267	cellular protein metabolic process
0.35	GO:0010467	gene expression
0.35	GO:0009059	macromolecule biosynthetic process

0.39	GO:0046872	metal ion binding
0.37	GO:0005515	protein binding
0.37	GO:0003735	structural constituent of ribosome

0.75	GO:0045202	synapse
0.49	GO:0005737	cytoplasm
0.39	GO:0005886	plasma membrane
0.36	GO:1990904	ribonucleoprotein complex
0.36	GO:0043232	intracellular non-membrane-bounded organelle

sp|Q802T2|ALG6_CHICK
Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
Search

ALG6

0.60	Alpha-1,3-glucosyltransferase

0.74	GO:0006486	protein glycosylation
0.48	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process
0.34	GO:0040003	chitin-based cuticle development
0.33	GO:0008299	isoprenoid biosynthetic process
0.32	GO:0016310	phosphorylation

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.34	GO:0004496	mevalonate kinase activity
0.33	GO:0035091	phosphatidylinositol binding
0.33	GO:0008080	N-acetyltransferase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.69	EC:2.4.1	GO:0016758
0.34	KEGG:R02245	GO:0004496

sp|Q804A9|DAZL_CHICK
Deleted in azoospermia-like
Search

DAZL

0.97	Deleted in azoospermia like

0.79	GO:0007281	germ cell development
0.75	GO:0045727	positive regulation of translation
0.57	GO:0007147	female meiosis II
0.55	GO:0045836	positive regulation of meiotic nuclear division
0.54	GO:0006446	regulation of translational initiation
0.53	GO:0071695	anatomical structure maturation
0.53	GO:0048469	cell maturation
0.50	GO:0070935	3'-UTR-mediated mRNA stabilization
0.43	GO:0007283	spermatogenesis
0.40	GO:0007275	multicellular organism development

0.85	GO:0008494	translation activator activity
0.82	GO:0003730	mRNA 3'-UTR binding
0.49	GO:0042802	identical protein binding

0.53	GO:0005844	polysome
0.40	GO:0005737	cytoplasm
0.40	GO:0043234	protein complex
0.36	GO:0005634	nucleus
0.34	GO:0043232	intracellular non-membrane-bounded organelle

sp|Q804X6|FA9_CHICK
Coagulation factor IX
Search

0.44	Coagulation factor IXb

0.82	GO:0007596	blood coagulation
0.62	GO:0031638	zymogen activation
0.39	GO:0051897	positive regulation of protein kinase B signaling
0.38	GO:1900047	negative regulation of hemostasis
0.38	GO:0050819	negative regulation of coagulation
0.38	GO:0061045	negative regulation of wound healing
0.38	GO:0030193	regulation of blood coagulation
0.35	GO:0017187	peptidyl-glutamic acid carboxylation
0.35	GO:0072376	protein activation cascade
0.35	GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway

0.68	GO:0004252	serine-type endopeptidase activity
0.68	GO:0005509	calcium ion binding
0.36	GO:0005543	phospholipid binding
0.33	GO:0005515	protein binding
0.33	GO:0000287	magnesium ion binding
0.32	GO:0044877	macromolecular complex binding

0.65	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.36	GO:0005796	Golgi lumen
0.35	GO:0005788	endoplasmic reticulum lumen
0.35	GO:1905286	serine-type peptidase complex
0.33	GO:0005886	plasma membrane
0.31	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0004252

tr|Q805B1|Q805B1_CHICK
Tumor necrosis factor receptor associated factor-5
Search

TRAF5

0.97	LOW QUALITY PROTEIN: TNF receptor-associated factor 5

0.76	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.74	GO:0042981	regulation of apoptotic process
0.64	GO:0051090	regulation of DNA binding transcription factor activity
0.60	GO:0007165	signal transduction
0.59	GO:0050688	regulation of defense response to virus
0.58	GO:0071356	cellular response to tumor necrosis factor
0.55	GO:0001817	regulation of cytokine production
0.55	GO:0045087	innate immune response
0.50	GO:0044092	negative regulation of molecular function
0.49	GO:0044093	positive regulation of molecular function

0.84	GO:0005164	tumor necrosis factor receptor binding
0.63	GO:0031996	thioesterase binding
0.63	GO:0008270	zinc ion binding
0.57	GO:0031625	ubiquitin protein ligase binding
0.50	GO:0042802	identical protein binding
0.46	GO:0019903	protein phosphatase binding
0.45	GO:0019901	protein kinase binding
0.34	GO:0004871	signal transducer activity
0.33	GO:0004842	ubiquitin-protein transferase activity

0.52	GO:0005813	centrosome
0.50	GO:0035631	CD40 receptor complex
0.48	GO:0005829	cytosol
0.45	GO:0009898	cytoplasmic side of plasma membrane
0.34	GO:0005768	endosome
0.32	GO:0005739	mitochondrion

0.33

GO:0004842

sp|Q805F9|DDB1_CHICK
DNA damage-binding protein 1
Search

DDB1

0.88	Damage specific DNA binding protein 1

0.65	GO:0006281	DNA repair
0.58	GO:0046726	positive regulation by virus of viral protein levels in host cell
0.57	GO:1902188	positive regulation of viral release from host cell
0.57	GO:0035518	histone H2A monoubiquitination
0.56	GO:0045070	positive regulation of viral genome replication
0.55	GO:0051702	interaction with symbiont
0.54	GO:0034644	cellular response to UV
0.54	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.53	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.52	GO:0045732	positive regulation of protein catabolic process

0.58	GO:0071987	WD40-repeat domain binding
0.56	GO:0097602	cullin family protein binding
0.53	GO:0030674	protein binding, bridging
0.51	GO:0003684	damaged DNA binding
0.50	GO:0032403	protein complex binding

0.61	GO:0005634	nucleus
0.59	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex
0.57	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex
0.47	GO:0043233	organelle lumen
0.43	GO:0043234	protein complex
0.42	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0005694	chromosome
0.30	GO:0016020	membrane

tr|Q8AV16|Q8AV16_CHICK
B29/Ig-b
Search

CD79B

0.97	B-cell antigen receptor complex-associated protein beta chain

0.66	GO:0007166	cell surface receptor signaling pathway
0.60	GO:0002757	immune response-activating signal transduction
0.58	GO:0051260	protein homooligomerization
0.51	GO:0030183	B cell differentiation
0.39	GO:0035725	sodium ion transmembrane transport
0.39	GO:0002250	adaptive immune response
0.37	GO:0010469	regulation of receptor activity
0.37	GO:0034765	regulation of ion transmembrane transport

0.64	GO:0004888	transmembrane signaling receptor activity
0.56	GO:0042803	protein homodimerization activity
0.40	GO:0005248	voltage-gated sodium channel activity
0.37	GO:0005179	hormone activity
0.36	GO:0005244	voltage-gated ion channel activity
0.34	GO:0005131	growth hormone receptor binding

0.67	GO:0019815	B cell receptor complex
0.61	GO:0009897	external side of plasma membrane
0.54	GO:0005794	Golgi apparatus
0.53	GO:0005654	nucleoplasm
0.52	GO:0005829	cytosol
0.46	GO:0005887	integral component of plasma membrane
0.40	GO:0034706	sodium channel complex
0.38	GO:0070062	extracellular exosome

sp|Q8AV28|PCM1_CHICK
Pericentriolar material 1 protein
Search

PCM1

0.91	Pericentriolar material 1

0.85	GO:0034454	microtubule anchoring at centrosome
0.85	GO:0071539	protein localization to centrosome
0.79	GO:0060271	cilium assembly
0.52	GO:0022027	interkinetic nuclear migration
0.51	GO:0007098	centrosome cycle
0.50	GO:0097150	neuronal stem cell population maintenance
0.50	GO:0035176	social behavior
0.50	GO:0042073	intraciliary transport
0.50	GO:0031122	cytoplasmic microtubule organization
0.50	GO:0090316	positive regulation of intracellular protein transport

0.78	GO:0005813	centrosome
0.50	GO:0035869	ciliary transition zone
0.49	GO:0031965	nuclear membrane
0.49	GO:0044450	microtubule organizing center part
0.49	GO:0036064	ciliary basal body
0.48	GO:0045177	apical part of cell
0.45	GO:0005829	cytosol
0.41	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|Q8AV57|SDK2_CHICK
Protein sidekick-2
Search

0.86	Sidekick cell adhesion molecule 2

0.48	GO:0060219	camera-type eye photoreceptor cell differentiation
0.48	GO:0010842	retina layer formation
0.47	GO:0007416	synapse assembly
0.45	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.32	GO:0048148	behavioral response to cocaine
0.32	GO:0060998	regulation of dendritic spine development
0.31	GO:0005975	carbohydrate metabolic process

0.36	GO:0042802	identical protein binding
0.31	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.44	GO:0045202	synapse
0.36	GO:0030054	cell junction
0.33	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.31

GO:0004553

sp|Q8AV58|SDK1_CHICK
Protein sidekick-1
Search

SDK1

0.76	Sidekick cell adhesion molecule 1

0.53	GO:0048148	behavioral response to cocaine
0.52	GO:0060998	regulation of dendritic spine development
0.44	GO:0010842	retina layer formation
0.43	GO:0007416	synapse assembly
0.41	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.40	GO:0060219	camera-type eye photoreceptor cell differentiation
0.38	GO:0045216	cell-cell junction organization

0.39

GO:0042802

identical protein binding

0.41	GO:0045202	synapse
0.39	GO:0030054	cell junction
0.38	GO:0070062	extracellular exosome
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q8AV73|Q8AV73_CHICK
Ghrelin
Search

GHRL

0.90	Ghrelin and obestatin prepropeptide

0.76	GO:0010469	regulation of receptor activity
0.57	GO:2000851	positive regulation of glucocorticoid secretion
0.56	GO:0032095	regulation of response to food
0.56	GO:0032098	regulation of appetite
0.55	GO:2000506	negative regulation of energy homeostasis
0.54	GO:2000507	positive regulation of energy homeostasis
0.54	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep
0.54	GO:0060124	positive regulation of growth hormone secretion
0.54	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep
0.53	GO:0032102	negative regulation of response to external stimulus

0.87	GO:0016608	growth hormone-releasing hormone activity
0.53	GO:0031768	ghrelin receptor binding
0.51	GO:0030296	protein tyrosine kinase activator activity
0.34	GO:0005198	structural molecule activity

0.66	GO:0005576	extracellular region
0.48	GO:0098794	postsynapse
0.48	GO:0030424	axon
0.38	GO:0005737	cytoplasm
0.36	GO:0012506	vesicle membrane
0.36	GO:0048475	coated membrane
0.36	GO:0097708	intracellular vesicle
0.36	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0031984	organelle subcompartment

tr|Q8AV77|Q8AV77_CHICK
Hep21 protein
Search

tr|Q8AWB4|Q8AWB4_CHICK
Putative uncharacterized protein POFUT1
Search

POFUT1

0.96	GDP-fucose protein O-fucosyltransferase 1

0.79	GO:0006004	fucose metabolic process
0.61	GO:0036066	protein O-linked fucosylation
0.58	GO:0008593	regulation of Notch signaling pathway
0.58	GO:0001756	somitogenesis
0.56	GO:0007219	Notch signaling pathway
0.56	GO:0001525	angiogenesis
0.55	GO:0007507	heart development
0.52	GO:0007399	nervous system development
0.37	GO:0098609	cell-cell adhesion
0.37	GO:0009967	positive regulation of signal transduction

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.45	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0005112	Notch binding
0.34	GO:0003777	microtubule motor activity
0.34	GO:0008017	microtubule binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003677	DNA binding

0.51	GO:0005783	endoplasmic reticulum
0.36	GO:0031410	cytoplasmic vesicle
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.33	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016757

sp|Q8AWB5|FUT10_CHICK
Alpha-(1,3)-fucosyltransferase 10
Search

FUT10

0.79	Fucosyltransferase 10

0.80	GO:0036065	fucosylation
0.74	GO:0006486	protein glycosylation
0.50	GO:0097150	neuronal stem cell population maintenance
0.50	GO:0021799	cerebral cortex radially oriented cell migration
0.35	GO:0042355	L-fucose catabolic process
0.34	GO:0009566	fertilization
0.34	GO:0042060	wound healing
0.34	GO:0030097	hemopoiesis
0.34	GO:0006605	protein targeting
0.33	GO:0006457	protein folding

0.81	GO:0046920	alpha-(1->3)-fucosyltransferase activity
0.34	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity
0.32	GO:0003676	nucleic acid binding

0.80	GO:0032580	Golgi cisterna membrane
0.46	GO:0005783	endoplasmic reticulum
0.45	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0046920

sp|Q8AWB6|S35B1_CHICK
Solute carrier family 35 member B1
Search

SLC35B1

0.93	Endoplasmic reticulum nucleotide sugar transporter

0.55	GO:0055085	transmembrane transport
0.43	GO:1901264	carbohydrate derivative transport
0.43	GO:0015931	nucleobase-containing compound transport
0.41	GO:0015711	organic anion transport
0.40	GO:0008643	carbohydrate transport
0.34	GO:0002119	nematode larval development
0.33	GO:0007029	endoplasmic reticulum organization

0.48

GO:0005459

UDP-galactose transmembrane transporter activity

0.46	GO:0030173	integral component of Golgi membrane
0.44	GO:0030176	integral component of endoplasmic reticulum membrane

tr|Q8AWB8|Q8AWB8_CHICK
Structural maintenance of chromosomes protein
Search

sp|Q8AWC3|ARC_CHICK
Activity-regulated cytoskeleton-associated protein
Search

ARC

0.95	Activity-regulated cytoskeleton-associated protein (Fragment)

0.85	GO:0007492	endoderm development
0.82	GO:0009952	anterior/posterior pattern specification
0.78	GO:0016477	cell migration
0.71	GO:0007010	cytoskeleton organization
0.69	GO:0022604	regulation of cell morphogenesis
0.68	GO:2000969	positive regulation of AMPA receptor activity
0.66	GO:1900271	regulation of long-term synaptic potentiation
0.64	GO:0099175	regulation of postsynapse organization
0.64	GO:0060998	regulation of dendritic spine development
0.64	GO:0048168	regulation of neuronal synaptic plasticity

0.46

GO:0005515

protein binding

0.71	GO:0043197	dendritic spine
0.70	GO:0001669	acrosomal vesicle
0.69	GO:0014069	postsynaptic density
0.66	GO:0045211	postsynaptic membrane
0.63	GO:0005768	endosome
0.63	GO:0030054	cell junction
0.58	GO:0005856	cytoskeleton
0.48	GO:0043025	neuronal cell body
0.46	GO:0005938	cell cortex

sp|Q8AWC7|FUT11_CHICK
Alpha-(1,3)-fucosyltransferase 11
Search

FUT11

0.77	Fucosyltransferase 11

0.81	GO:0036065	fucosylation
0.74	GO:0006486	protein glycosylation
0.38	GO:0097150	neuronal stem cell population maintenance
0.38	GO:0021799	cerebral cortex radially oriented cell migration
0.35	GO:0006888	ER to Golgi vesicle-mediated transport
0.34	GO:0035459	cargo loading into vesicle
0.34	GO:0006886	intracellular protein transport
0.34	GO:0051668	localization within membrane
0.34	GO:0048194	Golgi vesicle budding

0.81	GO:0008417	fucosyltransferase activity
0.34	GO:0005515	protein binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.80	GO:0032580	Golgi cisterna membrane
0.37	GO:0005783	endoplasmic reticulum
0.37	GO:0005654	nucleoplasm
0.36	GO:0031982	vesicle
0.36	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space
0.34	GO:0030117	membrane coat
0.34	GO:0098805	whole membrane
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0008417

tr|Q8AWW1|Q8AWW1_CHICK
DNA polymerase kappa
Search

POLK

0.93	DNA polymerase kappa

0.65	GO:0071897	DNA biosynthetic process
0.64	GO:0006281	DNA repair
0.55	GO:0034644	cellular response to UV
0.35	GO:0006260	DNA replication
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.33	GO:0007165	signal transduction

0.71	GO:0003684	damaged DNA binding
0.69	GO:0003887	DNA-directed DNA polymerase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.54	GO:0090734	site of DNA damage
0.52	GO:0016604	nuclear body
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:2.7.7.7

GO:0003887

sp|Q8AWW5|CRIM1_CHICK
Cysteine-rich motor neuron 1 protein
Search

0.48	Cysteine-rich motor neuron 1 protein (Fragment)

0.74	GO:0010951	negative regulation of endopeptidase activity
0.57	GO:0001558	regulation of cell growth
0.34	GO:0048570	notochord morphogenesis
0.34	GO:0048009	insulin-like growth factor receptor signaling pathway
0.34	GO:0001756	somitogenesis
0.34	GO:0001568	blood vessel development
0.33	GO:0007399	nervous system development

0.77	GO:0004867	serine-type endopeptidase inhibitor activity
0.60	GO:0005520	insulin-like growth factor binding
0.36	GO:0030165	PDZ domain binding
0.35	GO:0005010	insulin-like growth factor-activated receptor activity

0.50	GO:0005576	extracellular region
0.33	GO:0031982	vesicle
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q8AXL1|SAT1_CHICK
Diamine acetyltransferase 1
Search

SAT1

0.96	Spermidine/spermine N-acetyltransferase

0.54	GO:0001525	angiogenesis
0.51	GO:0032918	spermidine acetylation
0.50	GO:0046208	spermine catabolic process
0.49	GO:0042127	regulation of cell proliferation
0.43	GO:0009447	putrescine catabolic process
0.38	GO:0032919	spermine acetylation
0.34	GO:0006596	polyamine biosynthetic process

0.85	GO:0004145	diamine N-acetyltransferase activity
0.51	GO:0019809	spermidine binding
0.50	GO:0042802	identical protein binding

0.42	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:2.3.1.57

GO:0004145

sp|Q8AXP2|CCD80_CHICK
Coiled-coil domain-containing protein 80
Search

CCDC80

0.97	Nuclear envelope protein okuribin

0.78	GO:0010811	positive regulation of cell-substrate adhesion
0.74	GO:0030198	extracellular matrix organization
0.52	GO:0001756	somitogenesis
0.51	GO:0003073	regulation of systemic arterial blood pressure
0.36	GO:0007411	axon guidance

0.82	GO:0001968	fibronectin binding
0.76	GO:0008201	heparin binding

0.82	GO:0005614	interstitial matrix
0.76	GO:0005604	basement membrane
0.68	GO:0005615	extracellular space
0.36	GO:0019031	viral envelope
0.30	GO:0016020	membrane

tr|Q8AXQ0|Q8AXQ0_CHICK
Translocating chain-associated membrane protein
Search

TRAM1

0.88	Translocating chain-associated membrane protein 1

0.56	GO:0015031	protein transport
0.35	GO:0090150	establishment of protein localization to membrane
0.35	GO:0046907	intracellular transport
0.34	GO:0072599	establishment of protein localization to endoplasmic reticulum
0.33	GO:0016032	viral process
0.32	GO:0055085	transmembrane transport

0.33	GO:0004872	receptor activity
0.33	GO:0005515	protein binding

0.44	GO:0005783	endoplasmic reticulum
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

sp|Q8AXU9|SH3G3_CHICK
Endophilin-A3
Search

SH3GL3

0.96	SH3 domain containing GRB2 like 3, endophilin A3

0.71	GO:0006897	endocytosis
0.44	GO:0072318	clathrin coat disassembly
0.43	GO:0036465	synaptic vesicle recycling
0.42	GO:0099003	vesicle-mediated transport in synapse
0.40	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus
0.40	GO:0030100	regulation of endocytosis
0.40	GO:0097484	dendrite extension
0.37	GO:0099050	vesicle scission
0.37	GO:0097753	membrane bending
0.37	GO:0097749	membrane tubulation

0.49	GO:0042802	identical protein binding
0.40	GO:0008022	protein C-terminus binding
0.39	GO:0008289	lipid binding
0.37	GO:0031697	beta-1 adrenergic receptor binding
0.37	GO:0045296	cadherin binding
0.36	GO:0019899	enzyme binding
0.36	GO:0044325	ion channel binding
0.35	GO:0017124	SH3 domain binding
0.33	GO:0004888	transmembrane signaling receptor activity

0.49	GO:0005737	cytoplasm
0.40	GO:0097708	intracellular vesicle
0.40	GO:0045202	synapse
0.39	GO:0012505	endomembrane system
0.37	GO:0098805	whole membrane
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0070062	extracellular exosome
0.35	GO:0044446	intracellular organelle part
0.34	GO:0030054	cell junction
0.33	GO:0015629	actin cytoskeleton

sp|Q8AXV0|SH3G1_CHICK
Endophilin-A2
Search

SH3GL1

0.96	Kinase C and casein kinase II substrate protein 3

0.71	GO:0006897	endocytosis
0.61	GO:0072318	clathrin coat disassembly
0.58	GO:0036465	synaptic vesicle recycling
0.56	GO:0099003	vesicle-mediated transport in synapse
0.47	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus
0.47	GO:0030100	regulation of endocytosis
0.47	GO:0097484	dendrite extension
0.41	GO:1903421	regulation of synaptic vesicle recycling
0.41	GO:0098815	modulation of excitatory postsynaptic potential
0.39	GO:0099050	vesicle scission

0.53	GO:0045296	cadherin binding
0.53	GO:0042802	identical protein binding
0.42	GO:0031697	beta-1 adrenergic receptor binding
0.42	GO:0008022	protein C-terminus binding
0.40	GO:0044325	ion channel binding
0.40	GO:0019902	phosphatase binding
0.39	GO:0008289	lipid binding
0.39	GO:0017124	SH3 domain binding
0.38	GO:0051020	GTPase binding
0.36	GO:0019901	protein kinase binding

0.53	GO:0045202	synapse
0.49	GO:0005737	cytoplasm
0.44	GO:0097708	intracellular vesicle
0.42	GO:0012505	endomembrane system
0.40	GO:0002102	podosome
0.38	GO:0098805	whole membrane
0.38	GO:0030054	cell junction
0.38	GO:0098588	bounding membrane of organelle
0.37	GO:0042995	cell projection
0.35	GO:0070062	extracellular exosome

sp|Q8AXV1|SH3G2_CHICK
Endophilin-A1
Search

SH3GL2

0.92	Endophilin-1

0.71	GO:0006897	endocytosis
0.58	GO:0072318	clathrin coat disassembly
0.56	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus
0.55	GO:0097484	dendrite extension
0.55	GO:0036465	synaptic vesicle recycling
0.54	GO:0002090	regulation of receptor internalization
0.53	GO:0099003	vesicle-mediated transport in synapse
0.40	GO:0099050	vesicle scission
0.39	GO:0097753	membrane bending
0.39	GO:0097749	membrane tubulation

0.50	GO:0042802	identical protein binding
0.40	GO:0045296	cadherin binding
0.37	GO:0008289	lipid binding
0.37	GO:0008022	protein C-terminus binding
0.37	GO:0019901	protein kinase binding

0.51	GO:0005769	early endosome
0.50	GO:0045202	synapse
0.38	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.35	GO:0044433	cytoplasmic vesicle part
0.35	GO:0098805	whole membrane
0.35	GO:0045334	clathrin-coated endocytic vesicle
0.35	GO:0098588	bounding membrane of organelle
0.34	GO:0002102	podosome
0.34	GO:0012506	vesicle membrane

sp|Q8AXY6|MUSK_CHICK
Muscle, skeletal receptor tyrosine protein kinase
Search

MUSK

0.58	Muscle associated receptor tyrosine kinase

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.55	GO:0007528	neuromuscular junction development
0.48	GO:0001934	positive regulation of protein phosphorylation
0.47	GO:0001941	postsynaptic membrane organization
0.47	GO:0043113	receptor clustering
0.46	GO:0030517	negative regulation of axon extension
0.45	GO:0008045	motor neuron axon guidance
0.45	GO:0007416	synapse assembly
0.44	GO:0048589	developmental growth
0.39	GO:0008582	regulation of synaptic growth at neuromuscular junction

0.76	GO:0004713	protein tyrosine kinase activity
0.58	GO:0019199	transmembrane receptor protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0042802	identical protein binding
0.35	GO:0030165	PDZ domain binding
0.33	GO:0019901	protein kinase binding
0.33	GO:0046872	metal ion binding

0.48	GO:0043235	receptor complex
0.45	GO:0045211	postsynaptic membrane
0.37	GO:0030054	cell junction
0.36	GO:0031594	neuromuscular junction
0.34	GO:0005887	integral component of plasma membrane
0.34	GO:0009897	external side of plasma membrane
0.33	GO:0042995	cell projection

0.76

GO:0004713

sp|Q8AY65|MB211_CHICK
Putative nucleotidyltransferase MAB21L1
Search

MAB21L1

0.96	Mab-21 like 1

0.81	GO:0043010	camera-type eye development
0.79	GO:0008284	positive regulation of cell proliferation
0.42	GO:0010172	embryonic body morphogenesis

0.61	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm

tr|Q8AYA6|Q8AYA6_CHICK
Suppressor of cytokine signaling 2 variant 1
Search

SOCS2

0.97	Suppressor of cytokine signaling 2

0.83	GO:0046426	negative regulation of JAK-STAT cascade
0.77	GO:0001558	regulation of cell growth
0.65	GO:0016567	protein ubiquitination
0.62	GO:0035556	intracellular signal transduction
0.58	GO:0040015	negative regulation of multicellular organism growth
0.58	GO:0060396	growth hormone receptor signaling pathway
0.57	GO:0032355	response to estradiol
0.55	GO:0061377	mammary gland lobule development
0.54	GO:0045666	positive regulation of neuron differentiation
0.54	GO:0007595	lactation

0.85	GO:0008269	JAK pathway signal transduction adaptor activity
0.85	GO:0005159	insulin-like growth factor receptor binding
0.57	GO:0005131	growth hormone receptor binding
0.46	GO:0004860	protein kinase inhibitor activity
0.36	GO:0070513	death domain binding
0.35	GO:0005070	SH3/SH2 adaptor activity
0.33	GO:0035014	phosphatidylinositol 3-kinase regulator activity
0.32	GO:0016301	kinase activity
0.31	GO:0046872	metal ion binding

0.48	GO:0005737	cytoplasm
0.33	GO:0005942	phosphatidylinositol 3-kinase complex
0.33	GO:0005886	plasma membrane

sp|Q8AYC9|CHK1_CHICK
Serine/threonine-protein kinase Chk1
Search

CHEK1

0.49	Non-specific serine/threonine protein kinase

0.77	GO:0000077	DNA damage checkpoint
0.63	GO:0006468	protein phosphorylation
0.60	GO:0010767	regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage
0.58	GO:0007093	mitotic cell cycle checkpoint
0.58	GO:0048096	chromatin-mediated maintenance of transcription
0.57	GO:2000615	regulation of histone H3-K9 acetylation
0.56	GO:1902742	apoptotic process involved in development
0.56	GO:0018210	peptidyl-threonine modification
0.55	GO:0000086	G2/M transition of mitotic cell cycle
0.54	GO:0001833	inner cell mass cell proliferation

0.68	GO:0004674	protein serine/threonine kinase activity
0.57	GO:0035173	histone kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0019904	protein domain specific binding
0.37	GO:0004576	oligosaccharyl transferase activity
0.33	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors

0.50	GO:0005657	replication fork
0.50	GO:0000785	chromatin
0.49	GO:0005654	nucleoplasm
0.40	GO:0000794	condensed nuclear chromosome
0.40	GO:0005813	centrosome
0.38	GO:0000781	chromosome, telomeric region
0.37	GO:0005737	cytoplasm
0.36	GO:0005615	extracellular space
0.35	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.68

GO:0004674

sp|Q8AYD0|CADH5_CHICK
Cadherin-5
Search

CDH5

0.93	Cadherin 5, type 2 preproprotein variant (Fragment)

0.83	GO:0001955	blood vessel maturation
0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.59	GO:1901552	positive regulation of endothelial cell development
0.58	GO:1903140	regulation of establishment of endothelial barrier
0.55	GO:0050728	negative regulation of inflammatory response
0.55	GO:0045765	regulation of angiogenesis
0.55	GO:0007043	cell-cell junction assembly
0.54	GO:0007179	transforming growth factor beta receptor signaling pathway
0.54	GO:1904018	positive regulation of vasculature development
0.52	GO:2000114	regulation of establishment of cell polarity

0.70	GO:0005509	calcium ion binding
0.55	GO:0044325	ion channel binding
0.54	GO:0008013	beta-catenin binding
0.54	GO:0019903	protein phosphatase binding
0.49	GO:0005102	receptor binding

0.55	GO:0005886	plasma membrane
0.54	GO:0005913	cell-cell adherens junction
0.53	GO:0005923	bicellular tight junction
0.51	GO:0009986	cell surface
0.50	GO:0098552	side of membrane
0.30	GO:0016021	integral component of membrane

tr|Q8AYE5|Q8AYE5_CHICK
T-box transcription factor Tbx22
Search

TBX22

0.86	T-box transcription factor TBX22

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:1902679	negative regulation of RNA biosynthetic process
0.43	GO:0072001	renal system development
0.37	GO:0060829	negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation
0.36	GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development
0.36	GO:0003163	sinoatrial node development
0.36	GO:0090103	cochlea morphogenesis

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.51	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0001106	RNA polymerase II transcription corepressor activity
0.35	GO:0001085	RNA polymerase II transcription factor binding
0.35	GO:0042803	protein homodimerization activity
0.35	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.35	GO:0017053	transcriptional repressor complex
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|Q8AYG9|Q8AYG9_CHICK
Ferritin
Search

0.62

Ferritin

0.76	GO:0006879	cellular iron ion homeostasis
0.75	GO:0006826	iron ion transport
0.38	GO:0051238	sequestering of metal ion
0.37	GO:0051651	maintenance of location in cell

0.76

GO:0008199

ferric iron binding

0.33

GO:0005737

cytoplasm

tr|Q8AYN2|Q8AYN2_CHICK
TALE homeodomain transcription factor Prep2
Search

PKNOX2

0.97	PBX/knotted 1 homeobox 2

0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:0010468	regulation of gene expression
0.41	GO:0030218	erythrocyte differentiation
0.41	GO:0030217	T cell differentiation
0.41	GO:0001525	angiogenesis
0.41	GO:0043010	camera-type eye development
0.39	GO:0006366	transcription by RNA polymerase II
0.39	GO:1902680	positive regulation of RNA biosynthetic process

0.57	GO:0003785	actin monomer binding
0.54	GO:0003677	DNA binding
0.53	GO:0051015	actin filament binding
0.52	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.40	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.39	GO:0046982	protein heterodimerization activity

0.60	GO:0005634	nucleus
0.57	GO:0045171	intercellular bridge
0.51	GO:0015629	actin cytoskeleton
0.50	GO:0015630	microtubule cytoskeleton
0.48	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.40	GO:0005737	cytoplasm
0.39	GO:0005667	transcription factor complex

sp|Q8AYS7|CENPI_CHICK
Centromere protein I
Search

CENPI

0.97	Centromere protein I

0.82	GO:0034508	centromere complex assembly
0.36	GO:0007548	sex differentiation
0.35	GO:0031055	chromatin remodeling at centromere
0.35	GO:0061641	CENP-A containing chromatin organization
0.35	GO:0006336	DNA replication-independent nucleosome assembly
0.35	GO:0043486	histone exchange
0.35	GO:0022602	ovulation cycle process
0.34	GO:0007062	sister chromatid cohesion
0.34	GO:0022412	cellular process involved in reproduction in multicellular organism
0.34	GO:0048608	reproductive structure development

0.33	GO:0005515	protein binding
0.32	GO:0008270	zinc ion binding

0.78	GO:0000776	kinetochore
0.53	GO:0016604	nuclear body
0.48	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q8AYS8|KCMA1_CHICK
Calcium-activated potassium channel subunit alpha-1
Search

KCNMA1

0.84	Calcium-activated potassium channel

0.72	GO:0071805	potassium ion transmembrane transport
0.43	GO:0034465	response to carbon monoxide
0.42	GO:0045794	negative regulation of cell volume
0.42	GO:0060073	micturition
0.41	GO:0030007	cellular potassium ion homeostasis
0.41	GO:0051592	response to calcium ion
0.40	GO:0001666	response to hypoxia
0.40	GO:0042391	regulation of membrane potential
0.40	GO:0006970	response to osmotic stress
0.40	GO:0014832	urinary bladder smooth muscle contraction

0.85	GO:0060072	large conductance calcium-activated potassium channel activity
0.76	GO:0005249	voltage-gated potassium channel activity
0.39	GO:0003779	actin binding
0.35	GO:0046872	metal ion binding

0.76	GO:0008076	voltage-gated potassium channel complex
0.42	GO:0016324	apical plasma membrane
0.41	GO:0005901	caveola
0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0043195	terminal bouton
0.34	GO:0009897	external side of plasma membrane
0.34	GO:0070062	extracellular exosome
0.34	GO:0045211	postsynaptic membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment

sp|Q8JFP1|IF4A2_CHICK
Eukaryotic initiation factor 4A-II
Search

EIF4A2

0.65	Eukaryotic initiation factor 4A-III

0.72	GO:0006413	translational initiation
0.56	GO:1900260	negative regulation of RNA-directed 5'-3' RNA polymerase activity
0.52	GO:1990823	response to leukemia inhibitory factor
0.49	GO:0071345	cellular response to cytokine stimulus
0.47	GO:0010501	RNA secondary structure unwinding
0.38	GO:0010468	regulation of gene expression
0.34	GO:0006401	RNA catabolic process
0.34	GO:0034248	regulation of cellular amide metabolic process
0.33	GO:0016071	mRNA metabolic process
0.33	GO:0032268	regulation of cellular protein metabolic process

0.78	GO:0004004	ATP-dependent RNA helicase activity
0.73	GO:0003743	translation initiation factor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.49	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005730	nucleolus
0.35	GO:0016281	eukaryotic translation initiation factor 4F complex
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|Q8JFP6|Q8JFP6_CHICK
Kv channel-interacting protein
Search

KCNIP2

0.90	Kv channel-interacting protein 2

0.45	GO:0045163	clustering of voltage-gated potassium channels
0.44	GO:0097623	potassium ion export across plasma membrane
0.44	GO:0086009	membrane repolarization
0.41	GO:1901379	regulation of potassium ion transmembrane transport
0.39	GO:0065009	regulation of molecular function
0.36	GO:0005513	detection of calcium ion
0.36	GO:0086001	cardiac muscle cell action potential
0.36	GO:0061337	cardiac conduction
0.36	GO:0051291	protein heterooligomerization
0.36	GO:0006936	muscle contraction

0.68	GO:0005509	calcium ion binding
0.44	GO:0015459	potassium channel regulator activity
0.44	GO:0005250	A-type (transient outward) potassium channel activity
0.43	GO:0047485	protein N-terminus binding
0.43	GO:0044325	ion channel binding
0.38	GO:0042802	identical protein binding
0.36	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
0.36	GO:0046923	ER retention sequence binding

0.42	GO:0008076	voltage-gated potassium channel complex
0.35	GO:0030425	dendrite
0.34	GO:0005737	cytoplasm

sp|Q8JFQ4|RDM1_CHICK
RAD52 motif-containing protein 1
Search

RDM1

0.97	RAD52 motif-containing protein 1

0.63	GO:0006310	DNA recombination
0.63	GO:0006281	DNA repair

0.56	GO:0003723	RNA binding
0.36	GO:0003677	DNA binding
0.34	GO:0005515	protein binding

0.49	GO:0005730	nucleolus
0.46	GO:0005829	cytosol
0.40	GO:0015030	Cajal body
0.40	GO:0016605	PML body

sp|Q8JG30|ST1B1_CHICK
Sulfotransferase family cytosolic 1B member 1
Search

0.55	Sulfotransferase

0.71	GO:0042403	thyroid hormone metabolic process
0.69	GO:0051923	sulfation
0.64	GO:0006805	xenobiotic metabolic process
0.51	GO:0006068	ethanol catabolic process
0.50	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.48	GO:0009812	flavonoid metabolic process
0.45	GO:0030855	epithelial cell differentiation
0.41	GO:0008202	steroid metabolic process
0.39	GO:0000103	sulfate assimilation
0.38	GO:0006584	catecholamine metabolic process

0.78	GO:0008146	sulfotransferase activity
0.34	GO:0005496	steroid binding
0.34	GO:0005515	protein binding

0.37	GO:0005829	cytosol
0.34	GO:0031965	nuclear membrane
0.34	GO:0005764	lysosome
0.30	GO:0016021	integral component of membrane

0.78

GO:0008146

sp|Q8JG33|WFDC1_CHICK
WAP four-disulfide core domain protein 1
Search

WFDC1

0.97	WAP four-disulfide core domain protein 1

0.75	GO:0010466	negative regulation of peptidase activity
0.51	GO:0061045	negative regulation of wound healing
0.51	GO:0050728	negative regulation of inflammatory response
0.46	GO:0001558	regulation of cell growth
0.39	GO:0032355	response to estradiol
0.39	GO:0050680	negative regulation of epithelial cell proliferation
0.38	GO:0052548	regulation of endopeptidase activity
0.37	GO:0070588	calcium ion transmembrane transport
0.36	GO:0042493	response to drug
0.36	GO:0099132	ATP hydrolysis coupled cation transmembrane transport

0.75	GO:0030414	peptidase inhibitor activity
0.38	GO:0061135	endopeptidase regulator activity
0.38	GO:0005388	calcium-transporting ATPase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding
0.31	GO:0019842	vitamin binding
0.31	GO:0050662	coenzyme binding

0.65	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.38

EC:3.6.3.8

GO:0005388

sp|Q8JG54|RGMA_CHICK
Repulsive guidance molecule A
Search

RGMA

0.97	Repulsive guidance molecule A

0.84	GO:0048681	negative regulation of axon regeneration
0.79	GO:0030509	BMP signaling pathway
0.52	GO:1900121	negative regulation of receptor binding
0.52	GO:0051044	positive regulation of membrane protein ectodomain proteolysis
0.50	GO:0001843	neural tube closure
0.50	GO:0030510	regulation of BMP signaling pathway
0.48	GO:0031175	neuron projection development
0.47	GO:0043547	positive regulation of GTPase activity
0.37	GO:0048671	negative regulation of collateral sprouting
0.37	GO:0010976	positive regulation of neuron projection development

0.81	GO:0015026	coreceptor activity
0.46	GO:0005102	receptor binding

0.47	GO:0009986	cell surface
0.39	GO:0031225	anchored component of membrane
0.38	GO:0005886	plasma membrane
0.36	GO:0043005	neuron projection
0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q8JG64|PDIA3_CHICK
Protein disulfide-isomerase A3
Search

PDIA3

0.57	Protein disulfide-isomerase A3

0.69	GO:0045454	cell redox homeostasis
0.68	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway
0.64	GO:0034976	response to endoplasmic reticulum stress
0.54	GO:0006457	protein folding
0.52	GO:1904148	cellular response to nonylphenol
0.51	GO:1901423	response to benzene
0.50	GO:1903334	positive regulation of protein folding
0.50	GO:0033595	response to genistein
0.49	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.48	GO:0071305	cellular response to vitamin D

0.72	GO:0003756	protein disulfide isomerase activity
0.64	GO:0015037	peptide disulfide oxidoreductase activity
0.59	GO:0042802	identical protein binding
0.49	GO:0019153	protein-disulfide reductase (glutathione) activity
0.48	GO:0042288	MHC class I protein binding
0.45	GO:0004629	phospholipase C activity
0.44	GO:0004197	cysteine-type endopeptidase activity
0.42	GO:0003723	RNA binding

0.74	GO:0042470	melanosome
0.72	GO:0005788	endoplasmic reticulum lumen
0.65	GO:0043209	myelin sheath
0.63	GO:0009986	cell surface
0.59	GO:0005615	extracellular space
0.52	GO:0005925	focal adhesion
0.51	GO:1903561	extracellular vesicle
0.48	GO:0042825	TAP complex
0.48	GO:0005790	smooth endoplasmic reticulum
0.47	GO:0055038	recycling endosome membrane

0.72

EC:5.3.4.1

GO:0003756

sp|Q8JGM4|QSOX1_CHICK
Sulfhydryl oxidase 1
Search

QSOX1

0.60	Sulfhydryl oxidase

0.64	GO:0045454	cell redox homeostasis
0.54	GO:0016242	negative regulation of macroautophagy
0.53	GO:0055114	oxidation-reduction process
0.35	GO:0002576	platelet degranulation
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0043687	post-translational protein modification
0.34	GO:0008285	negative regulation of cell proliferation
0.33	GO:0034453	microtubule anchoring
0.33	GO:0034975	protein folding in endoplasmic reticulum

0.84	GO:0016972	thiol oxidase activity
0.55	GO:0003756	protein disulfide isomerase activity
0.32	GO:0008017	microtubule binding

0.55	GO:0030173	integral component of Golgi membrane
0.54	GO:0045171	intercellular bridge
0.52	GO:0070062	extracellular exosome
0.38	GO:0043233	organelle lumen
0.37	GO:0044428	nuclear part
0.35	GO:0070820	tertiary granule
0.35	GO:0031091	platelet alpha granule
0.35	GO:0042581	specific granule
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0044433	cytoplasmic vesicle part

0.84

EC:1.8.3.2

GO:0016972

sp|Q8JGM8|BID_CHICK
BH3-interacting domain death agonist
Search

BID

0.97	BH3-interacting domain death agonist

0.79	GO:0043065	positive regulation of apoptotic process
0.52	GO:0032464	positive regulation of protein homooligomerization
0.52	GO:0001836	release of cytochrome c from mitochondria
0.51	GO:0010918	positive regulation of mitochondrial membrane potential
0.51	GO:0097284	hepatocyte apoptotic process
0.51	GO:0097345	mitochondrial outer membrane permeabilization
0.51	GO:2000269	regulation of fibroblast apoptotic process
0.51	GO:0090199	regulation of release of cytochrome c from mitochondria
0.50	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.50	GO:0010822	positive regulation of mitochondrion organization

0.47	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0046982	protein heterodimerization activity
0.36	GO:0005123	death receptor binding

0.49	GO:0005737	cytoplasm
0.46	GO:0031301	integral component of organelle membrane
0.41	GO:0031967	organelle envelope
0.39	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0070062	extracellular exosome
0.35	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0019867	outer membrane

sp|Q8JH64|BTK_CHICK
Tyrosine-protein kinase BTK
Search

BTK

0.59	Tyrosine-protein kinase

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.61	GO:0035556	intracellular signal transduction
0.60	GO:0002344	B cell affinity maturation
0.59	GO:0098761	cellular response to interleukin-7
0.57	GO:0030889	negative regulation of B cell proliferation
0.54	GO:0001818	negative regulation of cytokine production
0.54	GO:0048469	cell maturation
0.49	GO:0046777	protein autophosphorylation
0.46	GO:0045087	innate immune response
0.46	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

0.80	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.58	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0042802	identical protein binding
0.44	GO:0005102	receptor binding
0.34	GO:0046872	metal ion binding

0.55	GO:0098857	membrane microdomain
0.49	GO:0031410	cytoplasmic vesicle
0.49	GO:0005829	cytosol
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.44	GO:0005634	nucleus
0.39	GO:0042629	mast cell granule
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005856	cytoskeleton
0.34	GO:0005739	mitochondrion

0.80

GO:0004715

tr|Q8JH76|Q8JH76_CHICK
LIM domain only 4 protein
Search

LMO4

0.97	LOW QUALITY PROTEIN: LIM domain transcription factor LMO4

0.57	GO:0021527	spinal cord association neuron differentiation
0.56	GO:0021514	ventral spinal cord interneuron differentiation
0.55	GO:0042659	regulation of cell fate specification
0.55	GO:0021522	spinal cord motor neuron differentiation
0.55	GO:0048538	thymus development
0.55	GO:0003281	ventricular septum development
0.54	GO:0001843	neural tube closure
0.52	GO:0031333	negative regulation of protein complex assembly
0.52	GO:0030334	regulation of cell migration
0.51	GO:0033674	positive regulation of kinase activity

0.55	GO:0001158	enhancer sequence-specific DNA binding
0.54	GO:0046872	metal ion binding
0.49	GO:0008134	transcription factor binding
0.37	GO:0003712	transcription cofactor activity
0.33	GO:0003700	DNA binding transcription factor activity

0.52	GO:0031252	cell leading edge
0.50	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

tr|Q8JHJ4|Q8JHJ4_CHICK
B-cell-activating factor BAFF
Search

TNFSF13B

0.97	B-cell-activating factor BAFF

0.74	GO:0006955	immune response
0.55	GO:0031296	B cell costimulation
0.55	GO:0002636	positive regulation of germinal center formation
0.54	GO:0030890	positive regulation of B cell proliferation
0.54	GO:0048305	immunoglobulin secretion
0.53	GO:0031295	T cell costimulation
0.53	GO:0001782	B cell homeostasis
0.52	GO:0042102	positive regulation of T cell proliferation
0.35	GO:0010469	regulation of receptor activity
0.34	GO:0033209	tumor necrosis factor-mediated signaling pathway

0.83	GO:0005164	tumor necrosis factor receptor binding
0.35	GO:0005125	cytokine activity

0.50	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005615	extracellular space
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q8JHU0|HOP_CHICK
Homeodomain-only protein
Search

HOPX

0.97	Homeodomain-only protein (Fragment)

0.60	GO:0043415	positive regulation of skeletal muscle tissue regeneration
0.57	GO:0048286	lung alveolus development
0.57	GO:0051155	positive regulation of striated muscle cell differentiation
0.55	GO:0008016	regulation of heart contraction
0.55	GO:0043393	regulation of protein binding
0.54	GO:0016575	histone deacetylation
0.53	GO:0007507	heart development
0.53	GO:0000122	negative regulation of transcription by RNA polymerase II
0.52	GO:0001829	trophectodermal cell differentiation
0.49	GO:0051131	chaperone-mediated protein complex assembly

0.55	GO:0003677	DNA binding
0.36	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

tr|Q8JHU1|Q8JHU1_CHICK
Liver X receptor
Search

NR1H3

0.93	LOW QUALITY PROTEIN: oxysterols receptor LXR-alpha

0.79	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0097659	nucleic acid-templated transcription
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0010467	gene expression
0.53	GO:0034645	cellular macromolecule biosynthetic process
0.49	GO:0090341	negative regulation of secretion of lysosomal enzymes
0.48	GO:0090188	negative regulation of pancreatic juice secretion
0.48	GO:0010887	negative regulation of cholesterol storage

0.80	GO:0003707	steroid hormone receptor activity
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.44	GO:0001012	RNA polymerase II regulatory region DNA binding
0.42	GO:0003690	double-stranded DNA binding
0.40	GO:0046965	retinoid X receptor binding
0.36	GO:0015485	cholesterol binding
0.36	GO:0003713	transcription coactivator activity
0.35	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.43	GO:0005667	transcription factor complex
0.39	GO:0043235	receptor complex
0.38	GO:0000785	chromatin
0.37	GO:0070013	intracellular organelle lumen
0.32	GO:0005737	cytoplasm

tr|Q8JHU2|Q8JHU2_CHICK
Farnesoid X receptor
Search

NR1H4

0.90	Nuclear receptor subfamily 1 group H member 4

0.79	GO:0030522	intracellular receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.77	GO:1905695	positive regulation of phosphatidic acid biosynthetic process
0.77	GO:2001250	positive regulation of ammonia assimilation cycle
0.77	GO:0072615	interleukin-17 secretion
0.76	GO:0034255	regulation of urea metabolic process
0.76	GO:0034971	histone H3-R17 methylation
0.76	GO:0038183	bile acid signaling pathway
0.76	GO:1904179	positive regulation of adipose tissue development
0.76	GO:1904252	negative regulation of bile acid metabolic process

0.83	GO:0004887	thyroid hormone receptor activity
0.80	GO:0032052	bile acid binding
0.80	GO:0003707	steroid hormone receptor activity
0.76	GO:0038181	bile acid receptor activity
0.74	GO:0046965	retinoid X receptor binding
0.71	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.70	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.70	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.69	GO:0005496	steroid binding
0.67	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.70

GO:0005719

nuclear euchromatin

tr|Q8JHX2|Q8JHX2_CHICK
HMG-box transcription factor Tcf-1
Search

TCF7

0.86	HMG-box transcription factor Tcf-1

0.86	GO:0002681	somatic recombination of T cell receptor gene segments
0.83	GO:0060070	canonical Wnt signaling pathway
0.77	GO:0033151	V(D)J recombination
0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.51	GO:0071353	cellular response to interleukin-4
0.49	GO:0030538	embryonic genitalia morphogenesis
0.47	GO:0048619	embryonic hindgut morphogenesis
0.47	GO:0048557	embryonic digestive tract morphogenesis
0.47	GO:0046632	alpha-beta T cell differentiation
0.46	GO:0007399	nervous system development

0.82	GO:0008013	beta-catenin binding
0.54	GO:0003677	DNA binding
0.49	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.46	GO:0000791	euchromatin
0.44	GO:0031974	membrane-enclosed lumen
0.43	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|Q8JHZ8|PALD_CHICK
Paladin
Search

PALD1

0.96	Phosphatase domain containing, paladin 1

0.62	GO:0016311	dephosphorylation
0.48	GO:0006464	cellular protein modification process
0.39	GO:0001525	angiogenesis
0.36	GO:0006508	proteolysis
0.36	GO:0007050	cell cycle arrest
0.35	GO:1903047	mitotic cell cycle process
0.35	GO:0044843	cell cycle G1/S phase transition
0.34	GO:0051255	spindle midzone assembly
0.34	GO:0051231	spindle elongation
0.34	GO:0007096	regulation of exit from mitosis

0.62	GO:0016791	phosphatase activity
0.48	GO:0140096	catalytic activity, acting on a protein

0.57	GO:0005829	cytosol
0.49	GO:0005634	nucleus
0.34	GO:0072686	mitotic spindle
0.33	GO:0000922	spindle pole
0.33	GO:0005813	centrosome
0.30	GO:0031224	intrinsic component of membrane

0.62

EC:3.1.3 EC:3.1.3.41

GO:0016791

sp|Q8JIF5|ERAL1_CHICK
GTPase Era, mitochondrial
Search

ERAL1

0.68	GTPase Era, mitochondrial

0.45

GO:0000028

ribosomal small subunit assembly

0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.57	GO:0003723	RNA binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0032555	purine ribonucleotide binding
0.46	GO:0043024	ribosomal small subunit binding
0.36	GO:0003924	GTPase activity

0.43	GO:0005759	mitochondrial matrix
0.39	GO:0005829	cytosol
0.36	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane
0.34	GO:0005886	plasma membrane

tr|Q8JIG5|Q8JIG5_CHICK
Alpha-1-acid glycoprotein
Search

0.96	Alpha-1-acid glycoprotein 1

0.71

GO:0002682

regulation of immune system process

0.73

GO:0005615

extracellular space

sp|Q8JIR8|IMPG1_CHICK
Interphotoreceptor matrix proteoglycan 1
Search

IMPG1

0.91	Interphotoreceptor matrix proteoglycan 1

0.59

GO:0007601

visual perception

0.61	GO:0005201	extracellular matrix structural constituent
0.61	GO:0005540	hyaluronic acid binding

0.64	GO:0033165	interphotoreceptor matrix
0.30	GO:0044425	membrane part

sp|Q8JIS3|DER_CHICK
D-erythrulose reductase
Search

DCXR

0.70	Dicarbonyl and L-xylulose reductase

0.54	GO:0051262	protein tetramerization
0.52	GO:0005997	xylulose metabolic process
0.52	GO:0055114	oxidation-reduction process
0.50	GO:0051260	protein homooligomerization
0.48	GO:0006006	glucose metabolic process
0.43	GO:0006739	NADP metabolic process
0.41	GO:0042732	D-xylose metabolic process
0.36	GO:0019640	glucuronate catabolic process to xylulose 5-phosphate
0.35	GO:0006734	NADH metabolic process
0.34	GO:0007389	pattern specification process

0.58	GO:0050038	L-xylulose reductase (NADP+) activity
0.48	GO:0042802	identical protein binding
0.46	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
0.43	GO:0004090	carbonyl reductase (NADPH) activity
0.41	GO:0043621	protein self-association
0.37	GO:0047880	erythrulose reductase activity
0.36	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity
0.33	GO:0102131	3-oxo-glutaryl-[acp] methyl ester reductase activity
0.33	GO:0102132	3-oxo-pimeloyl-[acp] methyl ester reductase activity
0.33	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity

0.53	GO:0005881	cytoplasmic microtubule
0.48	GO:0005902	microvillus
0.47	GO:0005903	brush border
0.37	GO:0043227	membrane-bounded organelle
0.36	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space
0.35	GO:0097223	sperm part
0.34	GO:0016324	apical plasma membrane
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0012505	endomembrane system

0.58	EC:1.1.1.10	GO:0050038
0.58	KEGG:R01904	GO:0050038

tr|Q8JIV2|Q8JIV2_CHICK
Cyclin-dependent kinase inhibitor p27 Kip1
Search

CDKN1B

0.85	Cyclin dependent kinase inhibitor

0.84	GO:0007050	cell cycle arrest
0.82	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.75	GO:0042127	regulation of cell proliferation
0.62	GO:1902746	regulation of lens fiber cell differentiation
0.61	GO:1904030	negative regulation of cyclin-dependent protein kinase activity
0.60	GO:0071236	cellular response to antibiotic
0.60	GO:0071285	cellular response to lithium ion
0.60	GO:0048102	autophagic cell death
0.59	GO:0031116	positive regulation of microtubule polymerization
0.57	GO:0000082	G1/S transition of mitotic cell cycle

0.85	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.57	GO:0019903	protein phosphatase binding
0.56	GO:0030332	cyclin binding
0.54	GO:0019901	protein kinase binding
0.53	GO:0032403	protein complex binding
0.52	GO:0016301	kinase activity
0.40	GO:0030544	Hsp70 protein binding
0.39	GO:0051087	chaperone binding
0.36	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity
0.36	GO:0060089	molecular transducer activity

0.61	GO:0005634	nucleus
0.58	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex
0.49	GO:0005829	cytosol
0.40	GO:0005768	endosome
0.36	GO:0043234	protein complex
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:1902554	serine/threonine protein kinase complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle

0.35

GO:0016773

tr|Q8JIY0|Q8JIY0_CHICK
Syndecan
Search

SDC2

0.82

Syndecan

0.54	GO:0048814	regulation of dendrite morphogenesis
0.47	GO:0016477	cell migration
0.45	GO:0048813	dendrite morphogenesis
0.42	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.42	GO:0070121	Kupffer's vesicle development
0.41	GO:0002040	sprouting angiogenesis
0.41	GO:0048565	digestive tract development
0.40	GO:0007507	heart development
0.39	GO:0097435	supramolecular fiber organization
0.36	GO:0042060	wound healing

0.56	GO:0030165	PDZ domain binding
0.50	GO:0042802	identical protein binding
0.34	GO:0070053	thrombospondin receptor activity
0.33	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding

0.51	GO:0031012	extracellular matrix
0.44	GO:0009986	cell surface
0.37	GO:0005796	Golgi lumen
0.35	GO:0043202	lysosomal lumen
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0043025	neuronal cell body
0.34	GO:0045202	synapse
0.33	GO:0005886	plasma membrane
0.33	GO:0005925	focal adhesion
0.30	GO:0016021	integral component of membrane

sp|Q8JJC0|ZIC1_CHICK
Zinc finger protein ZIC 1
Search

ZIC1

0.66	Zinc finger of the cerebellum 1

0.56	GO:0007417	central nervous system development
0.56	GO:0060322	head development
0.54	GO:0048513	animal organ development
0.48	GO:0048598	embryonic morphogenesis
0.47	GO:0061351	neural precursor cell proliferation
0.47	GO:0008589	regulation of smoothened signaling pathway
0.46	GO:0007628	adult walking behavior
0.45	GO:0042307	positive regulation of protein import into nucleus
0.45	GO:0007389	pattern specification process
0.43	GO:0045944	positive regulation of transcription by RNA polymerase II

0.51	GO:0003676	nucleic acid binding
0.45	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0003682	chromatin binding
0.35	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.46	GO:0005634	nucleus
0.40	GO:0070013	intracellular organelle lumen
0.37	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q8QFM1|Q8QFM1_CHICK
Neuropeptide Y receptor Y1
Search

NPY1R

0.97	Neuropeptide Y receptor type 1

0.78	GO:0007218	neuropeptide signaling pathway
0.57	GO:0003151	outflow tract morphogenesis
0.57	GO:0007631	feeding behavior
0.56	GO:0019233	sensory perception of pain
0.56	GO:0040014	regulation of multicellular organism growth
0.55	GO:0008015	blood circulation
0.54	GO:0007626	locomotory behavior
0.49	GO:0006006	glucose metabolic process
0.46	GO:0065008	regulation of biological quality
0.45	GO:0007268	chemical synaptic transmission

0.83	GO:0004983	neuropeptide Y receptor activity
0.36	GO:0042277	peptide binding
0.35	GO:0042562	hormone binding
0.33	GO:0005515	protein binding

0.36	GO:0005886	plasma membrane
0.35	GO:0008021	synaptic vesicle
0.34	GO:0030424	axon
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q8QFN3|TM121_CHICK
Transmembrane protein 121
Search

TMEM121

0.75	Transmembrane protein 121

0.30

GO:0044425

membrane part

sp|Q8QFP1|NSG1_CHICK
Neuron-specific protein family member 1
Search

HGNC:18790

0.97	Neuronal vesicle trafficking-associated protein 1

0.85	GO:0007212	dopamine receptor signaling pathway
0.83	GO:0048268	clathrin coat assembly
0.59	GO:0099627	neurotransmitter receptor cycle
0.58	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane
0.56	GO:0042982	amyloid precursor protein metabolic process
0.56	GO:0001881	receptor recycling
0.51	GO:0006915	apoptotic process
0.43	GO:0098814	spontaneous synaptic transmission
0.42	GO:1900271	regulation of long-term synaptic potentiation
0.40	GO:0001921	positive regulation of receptor recycling

0.85	GO:0032051	clathrin light chain binding
0.37	GO:0005102	receptor binding
0.34	GO:0003677	DNA binding

0.55	GO:0016328	lateral plasma membrane
0.53	GO:0005770	late endosome
0.52	GO:0045211	postsynaptic membrane
0.47	GO:0005783	endoplasmic reticulum
0.43	GO:0043202	lysosomal lumen
0.42	GO:0055038	recycling endosome membrane
0.42	GO:0031901	early endosome membrane
0.41	GO:0032588	trans-Golgi network membrane
0.41	GO:0030425	dendrite
0.40	GO:0098845	postsynaptic endosome

sp|Q8QFP8|LIMK1_CHICK
LIM domain kinase 1
Search

LIMK1

0.92	LIM domain kinase 1

0.63	GO:0006468	protein phosphorylation
0.58	GO:0032233	positive regulation of actin filament bundle assembly
0.57	GO:0051444	negative regulation of ubiquitin-protein transferase activity
0.57	GO:0051492	regulation of stress fiber assembly
0.55	GO:0045773	positive regulation of axon extension
0.45	GO:0030036	actin cytoskeleton organization
0.44	GO:0001878	response to yeast
0.42	GO:0035556	intracellular signal transduction
0.36	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.52	GO:0031072	heat shock protein binding
0.49	GO:0046982	protein heterodimerization activity
0.42	GO:0004871	signal transducer activity
0.35	GO:0005201	extracellular matrix structural constituent

0.53	GO:0016607	nuclear speck
0.53	GO:0043005	neuron projection
0.53	GO:0030027	lamellipodium
0.52	GO:0005925	focal adhesion
0.48	GO:0005829	cytosol
0.44	GO:0005794	Golgi apparatus
0.37	GO:0030427	site of polarized growth
0.36	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005578	proteinaceous extracellular matrix

sp|Q8QFQ8|IL18_CHICK
Interleukin-18
Search

IL18

0.91	Interleukin-18

0.80	GO:0006954	inflammatory response
0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.68	GO:1902715	positive regulation of interferon-gamma secretion
0.66	GO:0050671	positive regulation of lymphocyte proliferation
0.65	GO:0035710	CD4-positive, alpha-beta T cell activation
0.50	GO:0051140	regulation of NK T cell proliferation
0.50	GO:0051135	positive regulation of NK T cell activation
0.50	GO:0035655	interleukin-18-mediated signaling pathway
0.50	GO:0032817	regulation of natural killer cell proliferation

0.81

GO:0005125

cytokine activity

0.73	GO:0005615	extracellular space
0.35	GO:0005622	intracellular

sp|Q8QFV0|KCNT1_CHICK
Potassium channel subfamily T member 1
Search

KCNT1

0.96	Potassium sodium-activated channel subfamily T member 1

0.71	GO:0006813	potassium ion transport
0.40	GO:0098662	inorganic cation transmembrane transport
0.30	GO:0009987	cellular process

0.46	GO:0015269	calcium-activated potassium channel activity
0.45	GO:0005249	voltage-gated potassium channel activity

0.45

GO:0008076

voltage-gated potassium channel complex

sp|Q8QFX1|RIMB2_CHICK
RIMS-binding protein 2
Search

RIMBP2

0.91	RIMS-binding protein 2

0.82

GO:0010923

negative regulation of phosphatase activity

0.44	GO:0045202	synapse
0.44	GO:0030054	cell junction
0.38	GO:0005886	plasma membrane

tr|Q8QG55|Q8QG55_CHICK
C-C motif chemokine
Search

CCL20

0.71	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.57	GO:0072679	thymocyte migration
0.54	GO:2000406	positive regulation of T cell migration
0.54	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.45	GO:0071674	mononuclear cell migration
0.44	GO:1990266	neutrophil migration
0.44	GO:0071347	cellular response to interleukin-1
0.43	GO:0071356	cellular response to tumor necrosis factor

0.84	GO:0008009	chemokine activity
0.56	GO:0031731	CCR6 chemokine receptor binding

0.73	GO:0005615	extracellular space
0.36	GO:0005622	intracellular

tr|Q8QG57|Q8QG57_CHICK
C-C motif chemokine
Search

CCL5

0.75	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.73	GO:0010469	regulation of receptor activity
0.71	GO:0070098	chemokine-mediated signaling pathway
0.69	GO:0006954	inflammatory response
0.65	GO:0009615	response to virus
0.55	GO:0097529	myeloid leukocyte migration
0.53	GO:0071347	cellular response to interleukin-1
0.53	GO:0034612	response to tumor necrosis factor
0.53	GO:0140131	positive regulation of lymphocyte chemotaxis

0.84	GO:0008009	chemokine activity
0.76	GO:0031729	CCR4 chemokine receptor binding
0.76	GO:0031726	CCR1 chemokine receptor binding
0.76	GO:0031730	CCR5 chemokine receptor binding
0.53	GO:0046817	chemokine receptor antagonist activity
0.52	GO:0016004	phospholipase activator activity
0.51	GO:0042056	chemoattractant activity
0.51	GO:0030298	receptor signaling protein tyrosine kinase activator activity
0.49	GO:0043621	protein self-association
0.48	GO:0004435	phosphatidylinositol phospholipase C activity

0.72	GO:0005615	extracellular space
0.37	GO:0005737	cytoplasm

0.48	EC:3.1.4.11	GO:0004435
0.48	KEGG:R03435	GO:0004435

tr|Q8QG58|Q8QG58_CHICK
Ngfi-A binding protein 1
Search

NAB1

0.97	Ngfi-A binding protein 1

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.61	GO:0001958	endochondral ossification
0.60	GO:0014037	Schwann cell differentiation
0.60	GO:0045682	regulation of epidermis development
0.59	GO:0042552	myelination
0.36	GO:0006351	transcription, DNA-templated

0.53

GO:0008134

transcription factor binding

0.61

GO:0005634

nucleus

sp|Q8QG60|CRY2_CHICK
Cryptochrome-2
Search

CRY2

0.87	Cryptochrome circadian clock 2

0.76	GO:0009649	entrainment of circadian clock
0.75	GO:2000847	negative regulation of corticosteroid hormone secretion
0.74	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway
0.73	GO:0042754	negative regulation of circadian rhythm
0.73	GO:2000849	regulation of glucocorticoid secretion
0.70	GO:0032922	circadian regulation of gene expression
0.70	GO:0009648	photoperiodism
0.67	GO:0032868	response to insulin
0.67	GO:0019915	lipid storage
0.66	GO:0045892	negative regulation of transcription, DNA-templated

0.68	GO:0035257	nuclear hormone receptor binding
0.64	GO:0019901	protein kinase binding
0.63	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.61	GO:0071949	FAD binding
0.45	GO:0016829	lyase activity
0.43	GO:0009881	photoreceptor activity
0.42	GO:0019902	phosphatase binding
0.40	GO:0000989	transcription factor activity, transcription factor binding
0.40	GO:0003697	single-stranded DNA binding
0.40	GO:0003684	damaged DNA binding

0.65	GO:0016607	nuclear speck
0.58	GO:0005829	cytosol
0.51	GO:0005739	mitochondrion
0.51	GO:0005667	transcription factor complex
0.44	GO:0097381	photoreceptor disc membrane
0.44	GO:0042622	photoreceptor outer segment membrane
0.37	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.45

GO:0016829

sp|Q8QG61|CRY1_CHICK
Cryptochrome-1
Search

CRY1

0.81	Cryptochrome circadian clock 1

0.66	GO:0009649	entrainment of circadian clock
0.63	GO:0009416	response to light stimulus
0.63	GO:0045892	negative regulation of transcription, DNA-templated
0.58	GO:2000850	negative regulation of glucocorticoid secretion
0.57	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway
0.57	GO:0006975	DNA damage induced protein phosphorylation
0.57	GO:1901700	response to oxygen-containing compound
0.56	GO:0048511	rhythmic process
0.56	GO:0042754	negative regulation of circadian rhythm
0.55	GO:2000001	regulation of DNA damage checkpoint

0.60	GO:0035257	nuclear hormone receptor binding
0.60	GO:0019902	phosphatase binding
0.55	GO:0000989	transcription factor activity, transcription factor binding
0.54	GO:0042826	histone deacetylase binding
0.54	GO:0003690	double-stranded DNA binding
0.53	GO:0001047	core promoter binding
0.51	GO:0019901	protein kinase binding
0.46	GO:0009881	photoreceptor activity
0.45	GO:0043565	sequence-specific DNA binding
0.42	GO:0016829	lyase activity

0.65	GO:0097381	photoreceptor disc membrane
0.64	GO:0042622	photoreceptor outer segment membrane
0.53	GO:0005829	cytosol
0.51	GO:0005634	nucleus
0.50	GO:0005667	transcription factor complex
0.43	GO:0005739	mitochondrion
0.36	GO:0043233	organelle lumen
0.36	GO:0005576	extracellular region
0.35	GO:0044446	intracellular organelle part

0.42

GO:0016829

tr|Q8QG94|Q8QG94_CHICK
Suppressor of fused homolog
Search

SUFU

0.93	Suppressor of fused

0.56	GO:0045879	negative regulation of smoothened signaling pathway
0.54	GO:0007224	smoothened signaling pathway
0.54	GO:0007275	multicellular organism development
0.53	GO:0042994	cytoplasmic sequestering of transcription factor
0.52	GO:1901620	regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.52	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.51	GO:0045992	negative regulation of embryonic development
0.50	GO:0001708	cell fate specification
0.49	GO:0051961	negative regulation of nervous system development
0.48	GO:0000122	negative regulation of transcription by RNA polymerase II

0.70	GO:0008134	transcription factor binding
0.50	GO:0008013	beta-catenin binding
0.48	GO:0019901	protein kinase binding
0.44	GO:0003714	transcription corepressor activity
0.39	GO:0004871	signal transducer activity
0.32	GO:0003676	nucleic acid binding

0.54	GO:0005634	nucleus
0.47	GO:0035301	Hedgehog signaling complex
0.47	GO:0005929	cilium
0.44	GO:0005737	cytoplasm
0.34	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0044422	organelle part

tr|Q8QGF8|Q8QGF8_CHICK
FSH beta
Search

FSHB

0.96	Follitropin subunit beta

0.76	GO:0010469	regulation of receptor activity
0.52	GO:0042699	follicle-stimulating hormone signaling pathway
0.50	GO:0060011	Sertoli cell proliferation
0.49	GO:0007179	transforming growth factor beta receptor signaling pathway
0.49	GO:0045780	positive regulation of bone resorption
0.48	GO:0045670	regulation of osteoclast differentiation
0.46	GO:0007267	cell-cell signaling
0.44	GO:0009755	hormone-mediated signaling pathway
0.43	GO:0010628	positive regulation of gene expression
0.40	GO:0009914	hormone transport

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.38	GO:0005737	cytoplasm
0.37	GO:0031982	vesicle
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q8QGH2|SUMO1_CHICK
Small ubiquitin-related modifier 1
Search

SUMO1

0.76	Small ubiquitin-related modifier

0.79	GO:0016925	protein sumoylation
0.52	GO:1902260	negative regulation of delayed rectifier potassium channel activity
0.52	GO:0045759	negative regulation of action potential
0.51	GO:0090204	protein localization to nuclear pore
0.51	GO:0030578	PML body organization
0.51	GO:0071276	cellular response to cadmium ion
0.51	GO:1901896	positive regulation of calcium-transporting ATPase activity
0.50	GO:0060021	palate development
0.49	GO:0086004	regulation of cardiac muscle cell contraction
0.49	GO:0034605	cellular response to heat

0.61	GO:0008134	transcription factor binding
0.50	GO:0015459	potassium channel regulator activity
0.50	GO:0044388	small protein activating enzyme binding
0.49	GO:0031386	protein tag
0.47	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0008022	protein C-terminus binding
0.47	GO:0051427	hormone receptor binding
0.46	GO:0030674	protein binding, bridging
0.38	GO:0019789	SUMO transferase activity
0.34	GO:0003723	RNA binding

0.59	GO:0005634	nucleus
0.48	GO:0035770	ribonucleoprotein granule
0.47	GO:0001741	XY body
0.47	GO:0008076	voltage-gated potassium channel complex
0.44	GO:0070013	intracellular organelle lumen
0.44	GO:0012505	endomembrane system
0.42	GO:0031967	organelle envelope
0.41	GO:0031090	organelle membrane
0.40	GO:1902494	catalytic complex
0.39	GO:0000792	heterochromatin

0.32

GO:0016491

sp|Q8QGH3|CAD20_CHICK
Cadherin-20
Search

CDH20

0.97	Cadherin 20, type 2

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.37	GO:0036032	neural crest cell delamination
0.36	GO:0001841	neural tube formation
0.35	GO:0060591	chondroblast differentiation
0.34	GO:0001502	cartilage condensation
0.34	GO:0034332	adherens junction organization
0.34	GO:0060173	limb development
0.34	GO:0042060	wound healing
0.34	GO:0016477	cell migration

0.70

GO:0005509

calcium ion binding

0.56	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q8QGM3|Q8QGM3_CHICK
Neuropeptide Y receptor 4
Search

0.96	Neuropeptide Y /peptide YY receptor Yb

0.79	GO:0007218	neuropeptide signaling pathway
0.53	GO:0007631	feeding behavior
0.51	GO:0008015	blood circulation
0.50	GO:0003151	outflow tract morphogenesis
0.49	GO:0019233	sensory perception of pain
0.48	GO:0040014	regulation of multicellular organism growth
0.47	GO:0007626	locomotory behavior
0.45	GO:0098916	anterograde trans-synaptic signaling
0.44	GO:0006006	glucose metabolic process
0.41	GO:0065008	regulation of biological quality

0.83	GO:0004983	neuropeptide Y receptor activity
0.48	GO:0042923	neuropeptide binding

0.36	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q8QGP3|CBPZ_CHICK
Carboxypeptidase Z
Search

CPZ

0.97	Carboxypeptidase Z

0.60	GO:0006508	proteolysis
0.42	GO:0051604	protein maturation
0.39	GO:0006518	peptide metabolic process
0.38	GO:0016055	Wnt signaling pathway
0.34	GO:0007275	multicellular organism development

0.76	GO:0004181	metallocarboxypeptidase activity
0.62	GO:0008270	zinc ion binding
0.43	GO:0004185	serine-type carboxypeptidase activity

0.42	GO:0005615	extracellular space
0.38	GO:0005578	proteinaceous extracellular matrix
0.36	GO:1903561	extracellular vesicle

0.76

GO:0004181

sp|Q8QGQ6|CLOCK_CHICK
Circadian locomoter output cycles protein kaput
Search

CLOCK

0.82	Circadian clock protein CLOCK

0.66	GO:0032922	circadian regulation of gene expression
0.66	GO:2000074	regulation of type B pancreatic cell development
0.66	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway
0.64	GO:0042634	regulation of hair cycle
0.63	GO:0071479	cellular response to ionizing radiation
0.62	GO:0050729	positive regulation of inflammatory response
0.62	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.62	GO:0050796	regulation of insulin secretion
0.61	GO:0051775	response to redox state
0.60	GO:0000077	DNA damage checkpoint

0.68	GO:0046983	protein dimerization activity
0.64	GO:0070888	E-box binding
0.62	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.62	GO:0001046	core promoter sequence-specific DNA binding
0.61	GO:0031490	chromatin DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.59	GO:0004402	histone acetyltransferase activity

0.75	GO:0005667	transcription factor complex
0.65	GO:0033391	chromatoid body
0.61	GO:0005634	nucleus
0.53	GO:0005829	cytosol
0.52	GO:0005694	chromosome
0.52	GO:0043233	organelle lumen
0.46	GO:0044446	intracellular organelle part

0.59

GO:0004402

sp|Q8QGQ7|BMAL2_CHICK
Aryl hydrocarbon receptor nuclear translocator-like protein 2
Search

ARNTL2

0.89	Aryl hydrocarbon receptor nuclear translocator like

0.58	GO:0042753	positive regulation of circadian rhythm
0.58	GO:0007623	circadian rhythm
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0051254	positive regulation of RNA metabolic process
0.52	GO:0010557	positive regulation of macromolecule biosynthetic process
0.52	GO:0031328	positive regulation of cellular biosynthetic process
0.49	GO:0090403	oxidative stress-induced premature senescence

0.68	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.59	GO:0070888	E-box binding
0.48	GO:0017162	aryl hydrocarbon receptor binding
0.48	GO:0043425	bHLH transcription factor binding
0.47	GO:0051879	Hsp90 protein binding
0.47	GO:0070491	repressing transcription factor binding
0.47	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.46	GO:0001047	core promoter binding
0.35	GO:0003682	chromatin binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.49	GO:0043233	organelle lumen
0.45	GO:0035770	ribonucleoprotein granule
0.44	GO:0044446	intracellular organelle part
0.34	GO:0005694	chromosome

sp|Q8QGQ8|PER2_CHICK
Period circadian protein homolog 2
Search

PER2

0.96	Period circadian protein like protein 2

0.63	GO:0007623	circadian rhythm
0.61	GO:0043153	entrainment of circadian clock by photoperiod
0.60	GO:0042753	positive regulation of circadian rhythm
0.60	GO:0007622	rhythmic behavior
0.59	GO:0042542	response to hydrogen peroxide
0.58	GO:0016525	negative regulation of angiogenesis
0.57	GO:0007626	locomotory behavior
0.57	GO:0009411	response to UV
0.57	GO:0009409	response to cold
0.44	GO:0051946	regulation of glutamate uptake involved in transmission of nerve impulse

0.55	GO:0003682	chromatin binding
0.40	GO:0000989	transcription factor activity, transcription factor binding
0.39	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.38	GO:1990226	histone methyltransferase binding
0.38	GO:0001222	transcription corepressor binding
0.38	GO:0042826	histone deacetylase binding
0.38	GO:0036002	pre-mRNA binding
0.37	GO:0035257	nuclear hormone receptor binding
0.37	GO:0001047	core promoter binding
0.37	GO:0019900	kinase binding

0.57	GO:0005634	nucleus
0.40	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0005829	cytosol
0.34	GO:0043232	intracellular non-membrane-bounded organelle

tr|Q8QGU2|Q8QGU2_CHICK
Peptidylprolyl isomerase
Search

FKBP1B

0.61	Peptidyl-prolyl cis-trans isomerase FKBP1B

0.85	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.85	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity
0.84	GO:0033197	response to vitamin E
0.83	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus
0.83	GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.82	GO:0098870	action potential propagation
0.82	GO:0010459	negative regulation of heart rate
0.81	GO:0051280	negative regulation of release of sequestered calcium ion into cytosol
0.81	GO:0048680	positive regulation of axon regeneration
0.81	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling

0.81	GO:0019855	calcium channel inhibitor activity
0.77	GO:0005528	FK506 binding
0.76	GO:0044325	ion channel binding
0.70	GO:0030551	cyclic nucleotide binding
0.70	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.66	GO:0005102	receptor binding
0.54	GO:0005219	ryanodine-sensitive calcium-release channel activity

0.82	GO:0016529	sarcoplasmic reticulum
0.75	GO:0030018	Z disc
0.73	GO:0034704	calcium channel complex
0.69	GO:0098827	endoplasmic reticulum subcompartment
0.65	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.64	GO:0098588	bounding membrane of organelle
0.46	GO:0005829	cytosol

0.70

GO:0003755

sp|Q8QGW7|LITAF_CHICK
Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog
Search

LITAF

0.90	Lipopolysaccharide-induced tumor necrosis factor-alpha factor

0.68	GO:0042347	negative regulation of NF-kappaB import into nucleus
0.64	GO:0071222	cellular response to lipopolysaccharide
0.61	GO:0001817	regulation of cytokine production
0.59	GO:0045944	positive regulation of transcription by RNA polymerase II
0.44	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.41	GO:0007568	aging
0.38	GO:0006351	transcription, DNA-templated
0.38	GO:0001816	cytokine production
0.38	GO:0007165	signal transduction
0.37	GO:0019953	sexual reproduction

0.68	GO:0050699	WW domain binding
0.62	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0008270	zinc ion binding
0.39	GO:0004871	signal transducer activity
0.38	GO:0005125	cytokine activity
0.36	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0005319	lipid transporter activity
0.35	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding

0.73	GO:0098560	cytoplasmic side of late endosome membrane
0.72	GO:0098559	cytoplasmic side of early endosome membrane
0.72	GO:0098574	cytoplasmic side of lysosomal membrane
0.61	GO:0009898	cytoplasmic side of plasma membrane
0.58	GO:0005794	Golgi apparatus
0.57	GO:0005654	nucleoplasm
0.56	GO:0005829	cytosol
0.41	GO:0031984	organelle subcompartment
0.35	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q8QGX4|PRKDC_CHICK
DNA-dependent protein kinase catalytic subunit
Search

PRKDC

0.81	DNA-dependent protein kinase catalytic subunit

0.80	GO:0006303	double-strand break repair via nonhomologous end joining
0.66	GO:1902400	intracellular signal transduction involved in G1 DNA damage checkpoint
0.64	GO:0002328	pro-B cell differentiation
0.64	GO:1902402	signal transduction involved in mitotic DNA damage checkpoint
0.64	GO:0002326	B cell lineage commitment
0.63	GO:0031571	mitotic G1 DNA damage checkpoint
0.63	GO:0033152	immunoglobulin V(D)J recombination
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035234	ectopic germ cell programmed cell death
0.62	GO:0002568	somatic diversification of T cell receptor genes

0.86	GO:0004677	DNA-dependent protein kinase activity
0.56	GO:0019904	protein domain specific binding
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0003677	DNA binding
0.54	GO:0008134	transcription factor binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0019899	enzyme binding
0.35	GO:0003723	RNA binding

0.65	GO:0070419	nonhomologous end joining complex
0.61	GO:0005634	nucleus
0.55	GO:0005667	transcription factor complex
0.53	GO:0032993	protein-DNA complex
0.52	GO:0070013	intracellular organelle lumen
0.47	GO:0043232	intracellular non-membrane-bounded organelle
0.46	GO:0044446	intracellular organelle part
0.39	GO:0031012	extracellular matrix
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.86

GO:0004677

tr|Q8QH01|Q8QH01_CHICK
Dimethylaniline monooxygenase [N-oxide-forming]
Search

FMO3

0.59	Flavin-containing monooxygenase

0.52	GO:0055114	oxidation-reduction process
0.43	GO:0009404	toxin metabolic process
0.43	GO:0006739	NADP metabolic process
0.40	GO:0017144	drug metabolic process
0.38	GO:0006082	organic acid metabolic process
0.38	GO:0032496	response to lipopolysaccharide
0.37	GO:0006970	response to osmotic stress
0.35	GO:0006805	xenobiotic metabolic process

0.78	GO:0004499	N,N-dimethylaniline monooxygenase activity
0.70	GO:0050661	NADP binding
0.66	GO:0050660	flavin adenine dinucleotide binding
0.45	GO:0034899	trimethylamine monooxygenase activity
0.34	GO:0016597	amino acid binding
0.34	GO:0005515	protein binding

0.42	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0031090	organelle membrane
0.34	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

0.78	EC:1.14.13.8	GO:0004499
0.45	KEGG:R05623	GO:0034899

sp|Q8QHI2|MCR_CHICK
Mineralocorticoid receptor (Fragment)
Search

0.68	Mineralocorticoid receptor variant A (Fragment)

0.79	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.42	GO:0051385	response to mineralocorticoid
0.41	GO:0071385	cellular response to glucocorticoid stimulus
0.40	GO:0060126	somatotropin secreting cell differentiation
0.40	GO:0071376	cellular response to corticotropin-releasing hormone stimulus
0.40	GO:0051459	regulation of corticotropin secretion

0.64	GO:0003707	steroid hormone receptor activity
0.62	GO:0043565	sequence-specific DNA binding
0.61	GO:0008270	zinc ion binding
0.59	GO:0003700	DNA binding transcription factor activity
0.51	GO:0005496	steroid binding
0.42	GO:0042562	hormone binding
0.36	GO:0003690	double-stranded DNA binding
0.35	GO:0001047	core promoter binding
0.35	GO:0005515	protein binding
0.33	GO:0008144	drug binding

0.61	GO:0005634	nucleus
0.41	GO:0043233	organelle lumen
0.40	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0043235	receptor complex
0.38	GO:0005829	cytosol
0.37	GO:1990794	basolateral part of cell
0.35	GO:0045177	apical part of cell

sp|Q8QHL3|VGFR1_CHICK
Vascular endothelial growth factor receptor 1
Search

FLT1

0.57	Kinase insert domain receptor like

0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.77	GO:0035924	cellular response to vascular endothelial growth factor stimulus
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.63	GO:1905563	negative regulation of vascular endothelial cell proliferation
0.62	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
0.61	GO:0010863	positive regulation of phospholipase C activity
0.61	GO:0002548	monocyte chemotaxis
0.61	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
0.60	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.58	GO:0045766	positive regulation of angiogenesis

0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.58	GO:0019838	growth factor binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0042802	identical protein binding
0.35	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity
0.35	GO:0046983	protein dimerization activity
0.34	GO:0019903	protein phosphatase binding

0.61	GO:0005887	integral component of plasma membrane
0.56	GO:0043235	receptor complex
0.53	GO:0015629	actin cytoskeleton
0.39	GO:0005768	endosome
0.37	GO:0005576	extracellular region
0.37	GO:0005925	focal adhesion
0.35	GO:0005634	nucleus
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part

0.80

GO:0004714

tr|Q8UUK1|Q8UUK1_CHICK
Preprocarboxypeptidase A
Search

CPA1

0.87	Carboxypeptidase A

0.60	GO:0006508	proteolysis
0.35	GO:0044257	cellular protein catabolic process

0.76	GO:0004181	metallocarboxypeptidase activity
0.62	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding

0.50	GO:0005615	extracellular space
0.34	GO:0005773	vacuole

0.76

GO:0004181

sp|Q8UUW7|KHDR1_CHICK
KH domain-containing, RNA-binding, signal transduction-associated protein 1
Search

KHDRBS1

0.94	KH RNA binding domain containing, signal transduction associated 1

0.59	GO:0046833	positive regulation of RNA export from nucleus
0.58	GO:0048024	regulation of mRNA splicing, via spliceosome
0.55	GO:0045948	positive regulation of translational initiation
0.52	GO:0009967	positive regulation of signal transduction
0.50	GO:0051259	protein oligomerization
0.50	GO:0007166	cell surface receptor signaling pathway
0.49	GO:0045892	negative regulation of transcription, DNA-templated
0.39	GO:0000086	G2/M transition of mitotic cell cycle
0.38	GO:0006397	mRNA processing
0.38	GO:0007283	spermatogenesis

0.59	GO:0008266	poly(U) RNA binding
0.59	GO:0008143	poly(A) binding
0.56	GO:0005070	SH3/SH2 adaptor activity
0.54	GO:0019904	protein domain specific binding
0.53	GO:0042802	identical protein binding
0.41	GO:0046982	protein heterodimerization activity
0.37	GO:0032403	protein complex binding
0.33	GO:0003677	DNA binding

0.48	GO:0005654	nucleoplasm
0.41	GO:0070618	Grb2-Sos complex
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|Q8UUX6|Q8UUX6_CHICK
GDP/GTP exchange factor VAV3
Search

VAV3

0.91	Vav 3 guanine nucleotide exchange factor b

0.77	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.62	GO:0035556	intracellular signal transduction
0.55	GO:0030890	positive regulation of B cell proliferation
0.55	GO:0030593	neutrophil chemotaxis
0.55	GO:0050853	B cell receptor signaling pathway
0.54	GO:0030032	lamellipodium assembly
0.54	GO:0008361	regulation of cell size
0.53	GO:1903727	positive regulation of phospholipid metabolic process
0.52	GO:0007229	integrin-mediated signaling pathway

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.55	GO:0048365	Rac GTPase binding
0.54	GO:0005154	epidermal growth factor receptor binding
0.51	GO:0046872	metal ion binding
0.39	GO:0001784	phosphotyrosine residue binding
0.35	GO:0005070	SH3/SH2 adaptor activity
0.34	GO:0005096	GTPase activator activity

0.45	GO:0005622	intracellular
0.41	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.37	GO:0005911	cell-cell junction
0.30	GO:0016021	integral component of membrane

sp|Q8UVC3|INVS_CHICK
Inversin
Search

INVS

0.66

Inversin

0.76	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.56	GO:0016055	Wnt signaling pathway
0.52	GO:0007275	multicellular organism development

0.57

GO:0005516

calmodulin binding

0.51	GO:0005856	cytoskeleton
0.40	GO:0005737	cytoplasm
0.36	GO:0099512	supramolecular fiber
0.35	GO:0005929	cilium
0.34	GO:0005634	nucleus
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q8UVD9|FUBP2_CHICK
Far upstream element-binding protein 2
Search

KHSRP

0.88	Far upstream element-binding protein 2

0.56	GO:2000628	regulation of miRNA metabolic process
0.56	GO:1904406	negative regulation of nitric oxide metabolic process
0.55	GO:1903427	negative regulation of reactive oxygen species biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:0010586	miRNA metabolic process
0.54	GO:0010468	regulation of gene expression
0.54	GO:0045428	regulation of nitric oxide biosynthetic process
0.53	GO:1903313	positive regulation of mRNA metabolic process
0.50	GO:0071345	cellular response to cytokine stimulus

0.59	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.34	GO:0003677	DNA binding

0.51	GO:0010494	cytoplasmic stress granule
0.48	GO:0005654	nucleoplasm
0.35	GO:0005829	cytosol
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.35	GO:0000178	exosome (RNase complex)
0.30	GO:0016021	integral component of membrane

tr|Q8UVE3|Q8UVE3_CHICK
Gap junction protein
Search

GJD2

0.64	Gap junction delta-2 protein (Fragment)

0.60	GO:0007154	cell communication
0.54	GO:0001508	action potential
0.51	GO:0007601	visual perception
0.44	GO:0023052	signaling
0.40	GO:0007416	synapse assembly
0.34	GO:0034220	ion transmembrane transport

0.38	GO:0005243	gap junction channel activity
0.35	GO:0022832	voltage-gated channel activity
0.35	GO:0022839	ion gated channel activity
0.35	GO:0008381	mechanosensitive ion channel activity
0.33	GO:0005515	protein binding

0.84	GO:0005922	connexin complex
0.30	GO:0031224	intrinsic component of membrane

tr|Q8UVF8|Q8UVF8_CHICK
Inhibitor of apoptosis protein 3
Search

XIAP

0.96	X-linked inhibitor of apoptosis

0.80	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process
0.73	GO:0051402	neuron apoptotic process
0.67	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.61	GO:1902530	positive regulation of protein linear polyubiquitination
0.60	GO:0090307	mitotic spindle assembly
0.59	GO:0016567	protein ubiquitination
0.45	GO:0006974	cellular response to DNA damage stimulus
0.45	GO:0016055	Wnt signaling pathway
0.39	GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway
0.38	GO:0043524	negative regulation of neuron apoptotic process

0.70	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.59	GO:0004842	ubiquitin-protein transferase activity
0.50	GO:0042802	identical protein binding
0.46	GO:0016874	ligase activity
0.42	GO:0002020	protease binding
0.42	GO:0061659	ubiquitin-like protein ligase activity
0.38	GO:0046872	metal ion binding
0.38	GO:0097110	scaffold protein binding
0.35	GO:0003735	structural constituent of ribosome

0.51	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.40	GO:0097179	protease inhibitor complex
0.36	GO:0043233	organelle lumen
0.35	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

0.46	EC:6	GO:0016874
0.59	KEGG:R03876	GO:0004842

tr|Q8UVG3|Q8UVG3_CHICK
Transcription factor RUNX2
Search

RUNX2

0.90	Runt-related transcription factor

0.69	GO:0045893	positive regulation of transcription, DNA-templated
0.58	GO:0002062	chondrocyte differentiation
0.55	GO:0097659	nucleic acid-templated transcription
0.52	GO:0002051	osteoblast fate commitment
0.52	GO:0032332	positive regulation of chondrocyte differentiation
0.51	GO:0010467	gene expression
0.51	GO:0042487	regulation of odontogenesis of dentin-containing tooth
0.51	GO:0002076	osteoblast development
0.50	GO:0034645	cellular macromolecule biosynthetic process
0.50	GO:0001958	endochondral ossification

0.60	GO:0003700	DNA binding transcription factor activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0003677	DNA binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0042809	vitamin D receptor binding
0.50	GO:0043425	bHLH transcription factor binding
0.49	GO:0070491	repressing transcription factor binding
0.46	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.46	GO:0005667	transcription factor complex
0.45	GO:0000785	chromatin
0.43	GO:0031974	membrane-enclosed lumen
0.37	GO:0005737	cytoplasm

sp|Q8UVJ7|CDHR1_CHICK
Cadherin-related family member 1
Search

CDHR1

0.97	Protocadherin-21

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.57	GO:0008594	photoreceptor cell morphogenesis
0.57	GO:0035845	photoreceptor cell outer segment organization
0.56	GO:0045494	photoreceptor cell maintenance
0.34	GO:0007601	visual perception
0.32	GO:0050896	response to stimulus

0.70	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding

0.57	GO:0042622	photoreceptor outer segment membrane
0.47	GO:0005887	integral component of plasma membrane

tr|Q8UVS4|Q8UVS4_CHICK
GAS41
Search

YEATS4

0.94	YEATS domain-containing protein 4

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0043968	histone H2A acetylation
0.53	GO:0043967	histone H4 acetylation
0.36	GO:0006413	translational initiation
0.36	GO:0040008	regulation of growth
0.34	GO:0000278	mitotic cell cycle
0.34	GO:1902680	positive regulation of RNA biosynthetic process
0.34	GO:0007010	cytoskeleton organization

0.53	GO:0008022	protein C-terminus binding
0.36	GO:0003743	translation initiation factor activity
0.34	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003796	lysozyme activity
0.32	GO:0003677	DNA binding
0.32	GO:0003735	structural constituent of ribosome

0.82	GO:0000812	Swr1 complex
0.78	GO:0035267	NuA4 histone acetyltransferase complex
0.52	GO:0031965	nuclear membrane
0.35	GO:0016363	nuclear matrix
0.34	GO:0005849	mRNA cleavage factor complex
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.33

EC:3.2.1.17

GO:0003796

tr|Q8UVS5|Q8UVS5_CHICK
Caspase-activated DNase
Search

DFFB

0.92	DNA fragmentation factor, beta polypeptide (caspase-activated DNase)

0.85	GO:0006309	apoptotic DNA fragmentation
0.48	GO:0030263	apoptotic chromosome condensation
0.43	GO:0051260	protein homooligomerization
0.38	GO:0007420	brain development

0.59	GO:0004518	nuclease activity
0.49	GO:0003677	DNA binding
0.48	GO:0140097	catalytic activity, acting on DNA
0.46	GO:0097718	disordered domain specific binding
0.42	GO:0042802	identical protein binding
0.42	GO:0019899	enzyme binding

0.64	GO:0005730	nucleolus
0.55	GO:0000790	nuclear chromatin
0.49	GO:0005737	cytoplasm
0.37	GO:0005654	nucleoplasm

0.59

EC:3.1

GO:0004518

sp|Q8UVV7|LIX1_CHICK
Protein limb expression 1
Search

LIX1

0.97	Limb and CNS expressed 1 like

0.85	GO:0097352	autophagosome maturation
0.41	GO:0006468	protein phosphorylation

0.43	GO:0004674	protein serine/threonine kinase activity
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding

0.48

GO:0005737

cytoplasm

0.43

GO:0004674

sp|Q8UW59|PARK7_CHICK
Protein DJ-1
Search

PARK7

0.96	Parkinsonism associated deglycase

0.85	GO:0140041	cellular detoxification of methylglyoxal
0.85	GO:0106046	guanine deglycation, glyoxal removal
0.85	GO:0036530	protein deglycation, methylglyoxal removal
0.85	GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity
0.83	GO:0033864	positive regulation of NAD(P)H oxidase activity
0.83	GO:1903189	glyoxal metabolic process
0.83	GO:0036471	cellular response to glyoxal
0.83	GO:0010273	detoxification of copper ion
0.83	GO:1903178	positive regulation of tyrosine 3-monooxygenase activity
0.83	GO:0036528	peptidyl-lysine deglycation

0.83	GO:0036470	tyrosine 3-monooxygenase activator activity
0.83	GO:0036478	L-dopa decarboxylase activator activity
0.80	GO:0044388	small protein activating enzyme binding
0.79	GO:1903135	cupric ion binding
0.78	GO:0016532	superoxide dismutase copper chaperone activity
0.78	GO:1903136	cuprous ion binding
0.77	GO:1990381	ubiquitin-specific protease binding
0.77	GO:0050681	androgen receptor binding
0.76	GO:0036524	protein deglycase activity
0.76	GO:0097110	scaffold protein binding

0.74	GO:0016605	PML body
0.73	GO:0005913	cell-cell adherens junction
0.71	GO:0005747	mitochondrial respiratory chain complex I
0.70	GO:0044297	cell body
0.69	GO:0048471	perinuclear region of cytoplasm
0.69	GO:0098793	presynapse
0.69	GO:0005758	mitochondrial intermembrane space
0.67	GO:0043005	neuron projection
0.66	GO:0005759	mitochondrial matrix
0.63	GO:0000785	chromatin

0.65

EC:1.11.1.15

GO:0051920

sp|Q8UW76|TBX20_CHICK
T-box transcription factor TBX20
Search

TBX20

0.82	T-box transcription factor TBX20

0.65	GO:0060577	pulmonary vein morphogenesis
0.65	GO:0035922	foramen ovale closure
0.64	GO:0036306	embryonic heart tube elongation
0.63	GO:0003180	aortic valve morphogenesis
0.63	GO:0001947	heart looping
0.63	GO:0003193	pulmonary valve formation
0.63	GO:0021524	visceral motor neuron differentiation
0.62	GO:0010991	negative regulation of SMAD protein complex assembly
0.62	GO:0060413	atrial septum morphogenesis
0.62	GO:0048738	cardiac muscle tissue development

0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0001105	RNA polymerase II transcription coactivator activity
0.59	GO:0001102	RNA polymerase II activating transcription factor binding
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q8UWB9|Q8UWB9_CHICK
CFTII
Search

FUT7

0.72	Fucosyltransferase 7

0.81	GO:0036065	fucosylation
0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.60	GO:0036211	protein modification process
0.56	GO:0044267	cellular protein metabolic process
0.49	GO:0006672	ceramide metabolic process
0.48	GO:0002522	leukocyte migration involved in immune response
0.47	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
0.36	GO:0042355	L-fucose catabolic process
0.33	GO:0009312	oligosaccharide biosynthetic process

0.81

GO:0008417

fucosyltransferase activity

0.81	GO:0032580	Golgi cisterna membrane
0.39	GO:0009986	cell surface
0.35	GO:0071944	cell periphery
0.33	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.81

GO:0008417

tr|Q8UWC1|Q8UWC1_CHICK
CFUT9
Search

FUT9

0.74	Fucosyltransferase 9

0.81	GO:0036065	fucosylation
0.74	GO:0006486	protein glycosylation
0.38	GO:0007399	nervous system development
0.35	GO:0042355	L-fucose catabolic process

0.81

GO:0008417

fucosyltransferase activity

0.81	GO:0032580	Golgi cisterna membrane
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0008417

tr|Q8UWC5|Q8UWC5_CHICK
Nuclear protein matrin 3
Search

MATR3

0.86	Nuclear protein matrin 3

0.36	GO:0003170	heart valve development
0.36	GO:0003281	ventricular septum development

0.63	GO:0008270	zinc ion binding
0.58	GO:0003723	RNA binding

0.58

GO:0005634

nucleus

tr|Q8UWF3|Q8UWF3_CHICK
Mothers against decapentaplegic homolog
Search

SMAD2

0.64	Mothers against decapentaplegic homolog

0.83	GO:0007179	transforming growth factor beta receptor signaling pathway
0.59	GO:1900224	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
0.58	GO:0007352	zygotic specification of dorsal/ventral axis
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0007182	common-partner SMAD protein phosphorylation
0.57	GO:0038092	nodal signaling pathway
0.57	GO:0007183	SMAD protein complex assembly
0.56	GO:0048340	paraxial mesoderm morphogenesis
0.56	GO:0070723	response to cholesterol
0.56	GO:0048617	embryonic foregut morphogenesis

0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
0.57	GO:0070410	co-SMAD binding
0.57	GO:0070878	primary miRNA binding
0.57	GO:0070411	I-SMAD binding
0.57	GO:0034713	type I transforming growth factor beta receptor binding
0.56	GO:0070412	R-SMAD binding
0.55	GO:0097718	disordered domain specific binding
0.55	GO:0003677	DNA binding
0.55	GO:0033613	activating transcription factor binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.57	GO:0071141	SMAD protein complex
0.49	GO:0000785	chromatin
0.49	GO:0005737	cytoplasm
0.47	GO:0070013	intracellular organelle lumen
0.35	GO:0097708	intracellular vesicle
0.30	GO:0016020	membrane

tr|Q8UWG6|Q8UWG6_CHICK
Mitogen-activated protein kinase
Search

MAPK1

0.58	Mitogen-activated protein kinase

0.80	GO:0000165	MAPK cascade
0.55	GO:0019858	cytosine metabolic process
0.54	GO:0060440	trachea formation
0.54	GO:0042473	outer ear morphogenesis
0.54	GO:0061308	cardiac neural crest cell development involved in heart development
0.54	GO:0060020	Bergmann glial cell differentiation
0.54	GO:1903351	cellular response to dopamine
0.54	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.53	GO:0070849	response to epidermal growth factor
0.53	GO:1904355	positive regulation of telomere capping

0.82	GO:0004707	MAP kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0004708	MAP kinase kinase activity
0.52	GO:0001784	phosphotyrosine residue binding
0.51	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.51	GO:0019902	phosphatase binding
0.47	GO:0042802	identical protein binding

0.53	GO:0031143	pseudopodium
0.48	GO:0005901	caveola
0.48	GO:0005829	cytosol
0.47	GO:0005925	focal adhesion
0.46	GO:0005770	late endosome
0.46	GO:0005769	early endosome
0.44	GO:0005634	nucleus
0.44	GO:0005739	mitochondrion
0.43	GO:0005794	Golgi apparatus
0.43	GO:0005856	cytoskeleton

0.82	EC:2.7.11.24	GO:0004707
0.82	KEGG:R00162	GO:0004707

tr|Q8UWG7|Q8UWG7_CHICK
60S ribosomal protein L6
Search

RPL6

0.69	60S ribosomal protein L6

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.45	GO:0000027	ribosomal large subunit assembly
0.43	GO:0031016	pancreas development
0.42	GO:0043009	chordate embryonic development
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.63	GO:0003735	structural constituent of ribosome
0.45	GO:0045296	cadherin binding
0.39	GO:0003723	RNA binding
0.33	GO:0003677	DNA binding
0.33	GO:0016874	ligase activity

0.60	GO:0005840	ribosome
0.47	GO:0044445	cytosolic part
0.47	GO:0005844	polysome
0.44	GO:0036464	cytoplasmic ribonucleoprotein granule
0.41	GO:0044446	intracellular organelle part
0.39	GO:0005634	nucleus
0.36	GO:0005925	focal adhesion
0.34	GO:0031672	A band
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane

0.33

GO:0016874

sp|Q90577|SRCA_CHICK
Sarcalumenin
Search

SRL

0.94	Sarcalumenin

0.53	GO:0014873	response to muscle activity involved in regulation of muscle adaptation
0.52	GO:0002115	store-operated calcium entry

0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0033018	sarcoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

sp|Q90578|VDHAP_CHICK
Vitamin D3 hydroxylase-associated protein
Search

0.95	vitamin D3 hydroxylase-associated protein isoform X1

0.75

GO:0004040

amidase activity

0.36	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane
0.30	GO:0044425	membrane part

0.75

EC:3.5.1.4

GO:0004040

tr|Q90582|Q90582_CHICK
CCAAT/Enhancer binding protein
Search

CEBPA

0.91	CCAAT enhancer binding protein alpha

0.58	GO:0030851	granulocyte differentiation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0030225	macrophage differentiation
0.54	GO:0001889	liver development
0.52	GO:0006366	transcription by RNA polymerase II
0.52	GO:0045600	positive regulation of fat cell differentiation
0.51	GO:0045669	positive regulation of osteoblast differentiation
0.51	GO:0045444	fat cell differentiation

0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.51	GO:0000987	proximal promoter sequence-specific DNA binding
0.48	GO:0019900	kinase binding
0.48	GO:0042803	protein homodimerization activity
0.45	GO:0003713	transcription coactivator activity
0.44	GO:0001046	core promoter sequence-specific DNA binding
0.44	GO:0035035	histone acetyltransferase binding
0.44	GO:0008134	transcription factor binding
0.43	GO:0042826	histone deacetylase binding

0.49	GO:0005654	nucleoplasm
0.45	GO:0090575	RNA polymerase II transcription factor complex
0.43	GO:0016363	nuclear matrix
0.42	GO:0000779	condensed chromosome, centromeric region
0.41	GO:0000790	nuclear chromatin
0.35	GO:0005737	cytoplasm
0.34	GO:0005730	nucleolus
0.32	GO:0005886	plasma membrane

sp|Q90584|COHA1_CHICK
Collagen alpha-1(XVII) chain
Search

COL17A1

0.97	Collagen type XVII alpha 1 chain

0.58	GO:0031581	hemidesmosome assembly
0.41	GO:0048925	lateral line system development
0.38	GO:0008544	epidermis development
0.35	GO:0007160	cell-matrix adhesion
0.34	GO:0050776	regulation of immune response

0.34

GO:0005515

protein binding

0.65	GO:0005581	collagen trimer
0.58	GO:0030056	hemidesmosome
0.39	GO:0005604	basement membrane
0.35	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0005911	cell-cell junction
0.34	GO:0005887	integral component of plasma membrane

sp|Q90592|GTR2_CHICK
Solute carrier family 2, facilitated glucose transporter member 2
Search

SLC2A2

0.95	Faciliated glucose transporter 2

0.67	GO:1904659	glucose transmembrane transport
0.59	GO:0070837	dehydroascorbic acid transport
0.45	GO:0046323	glucose import
0.44	GO:0001889	liver development
0.43	GO:0007420	brain development
0.41	GO:0042149	cellular response to glucose starvation
0.38	GO:0006461	protein complex assembly
0.38	GO:0032868	response to insulin
0.37	GO:1904016	response to Thyroglobulin triiodothyronine
0.37	GO:0071470	cellular response to osmotic stress

0.67	GO:0005355	glucose transmembrane transporter activity
0.59	GO:0033300	dehydroascorbic acid transmembrane transporter activity
0.42	GO:0043621	protein self-association
0.39	GO:0042802	identical protein binding
0.35	GO:0042910	xenobiotic transmembrane transporter activity
0.35	GO:0019900	kinase binding

0.54	GO:0016324	apical plasma membrane
0.53	GO:0005903	brush border
0.50	GO:0005911	cell-cell junction
0.42	GO:0001939	female pronucleus
0.41	GO:0030864	cortical actin cytoskeleton
0.41	GO:0045121	membrane raft
0.41	GO:0030496	midbody
0.41	GO:0016323	basolateral plasma membrane
0.39	GO:0031982	vesicle
0.39	GO:0005887	integral component of plasma membrane

sp|Q90593|GRP78_CHICK
78 kDa glucose-regulated protein
Search

HSPA5

0.72	Glucose-regulated protein 78

0.54	GO:1903895	negative regulation of IRE1-mediated unfolded protein response
0.53	GO:0090074	negative regulation of protein homodimerization activity
0.50	GO:0035437	maintenance of protein localization in endoplasmic reticulum
0.49	GO:0030335	positive regulation of cell migration
0.48	GO:0021589	cerebellum structural organization
0.48	GO:0006987	activation of signaling protein activity involved in unfolded protein response
0.47	GO:0006983	ER overload response
0.47	GO:0071353	cellular response to interleukin-4
0.46	GO:0021680	cerebellar Purkinje cell layer development
0.46	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0051787	misfolded protein binding
0.45	GO:0045296	cadherin binding
0.44	GO:0019904	protein domain specific binding
0.44	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0016887	ATPase activity
0.43	GO:0043022	ribosome binding

0.53	GO:0005788	endoplasmic reticulum lumen
0.48	GO:0042470	melanosome
0.47	GO:0034663	endoplasmic reticulum chaperone complex
0.45	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.45	GO:0030496	midbody
0.45	GO:0043209	myelin sheath
0.45	GO:0030176	integral component of endoplasmic reticulum membrane
0.45	GO:0008180	COP9 signalosome
0.43	GO:0009986	cell surface
0.42	GO:0005790	smooth endoplasmic reticulum

0.43

GO:0016887

sp|Q90595|MAFF_CHICK
Transcription factor MafF
Search

MAFF

0.96	Transcription factor MafF

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0006351	transcription, DNA-templated
0.45	GO:0045604	regulation of epidermal cell differentiation
0.44	GO:0035914	skeletal muscle cell differentiation
0.43	GO:0001701	in utero embryonic development
0.41	GO:1902680	positive regulation of RNA biosynthetic process
0.39	GO:0007567	parturition
0.38	GO:0007596	blood coagulation

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.39	GO:0005739	mitochondrion
0.38	GO:0043233	organelle lumen
0.36	GO:0044446	intracellular organelle part

sp|Q90596|MAFK_CHICK
Transcription factor MafK
Search

MAFK

0.93	Transcription factor MafK

0.57	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.42	GO:1902679	negative regulation of RNA biosynthetic process
0.40	GO:0007399	nervous system development
0.38	GO:1902680	positive regulation of RNA biosynthetic process
0.37	GO:0007596	blood coagulation

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.45	GO:0071535	RING-like zinc finger domain binding
0.42	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0001221	transcription cofactor binding
0.38	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.40	GO:0031974	membrane-enclosed lumen
0.38	GO:0005667	transcription factor complex
0.37	GO:0044446	intracellular organelle part

sp|Q90597|MX_CHICK
Interferon-induced GTP-binding protein Mx
Search

MX1

0.88	Interferon-induced GTP-binding protein Mx

0.39	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission
0.39	GO:0045087	innate immune response
0.38	GO:0000266	mitochondrial fission
0.37	GO:0051607	defense response to virus
0.36	GO:0034097	response to cytokine
0.36	GO:0061025	membrane fusion
0.33	GO:0071310	cellular response to organic substance

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0008017	microtubule binding

0.35	GO:0031966	mitochondrial membrane
0.35	GO:0005615	extracellular space
0.33	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005634	nucleus
0.32	GO:0005829	cytosol

sp|Q90600|RB_CHICK
Retinoblastoma-associated protein
Search

RB1

0.96	RB transcriptional corepressor 1

0.85	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.79	GO:0008285	negative regulation of cell proliferation
0.78	GO:0006915	apoptotic process
0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.60	GO:0043353	enucleate erythrocyte differentiation
0.59	GO:0045651	positive regulation of macrophage differentiation
0.59	GO:0071922	regulation of cohesin loading
0.58	GO:0034088	maintenance of mitotic sister chromatid cohesion
0.58	GO:0045445	myoblast differentiation

0.73	GO:0008134	transcription factor binding
0.58	GO:0061676	importin-alpha family protein binding
0.57	GO:0097718	disordered domain specific binding
0.55	GO:0051219	phosphoprotein binding
0.55	GO:0001047	core promoter binding
0.53	GO:0019900	kinase binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.50	GO:0042802	identical protein binding
0.35	GO:0051427	hormone receptor binding
0.34	GO:0003713	transcription coactivator activity

0.86	GO:0035189	Rb-E2F complex
0.57	GO:0008024	cyclin/CDK positive transcription elongation factor complex
0.56	GO:0016605	PML body
0.52	GO:0005819	spindle
0.35	GO:0016514	SWI/SNF complex
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|Q90602|Q90602_CHICK
Single stranded D box binding factor
Search

HNRNPAB

0.96	Heterogeneous nuclear ribonucleoprotein A/B

0.41	GO:0001837	epithelial to mesenchymal transition
0.38	GO:0045893	positive regulation of transcription, DNA-templated
0.38	GO:1904580	regulation of intracellular mRNA localization
0.38	GO:0000122	negative regulation of transcription by RNA polymerase II
0.37	GO:0071230	cellular response to amino acid stimulus
0.33	GO:0006351	transcription, DNA-templated

0.59	GO:0003723	RNA binding
0.37	GO:0043565	sequence-specific DNA binding
0.36	GO:0005515	protein binding
0.36	GO:0003700	DNA binding transcription factor activity
0.36	GO:0003690	double-stranded DNA binding
0.36	GO:0044877	macromolecular complex binding

0.61	GO:0019013	viral nucleocapsid
0.56	GO:0030529	intracellular ribonucleoprotein complex
0.47	GO:0005654	nucleoplasm
0.39	GO:0090575	RNA polymerase II transcription factor complex
0.38	GO:0120111	neuron projection cytoplasm
0.37	GO:0030425	dendrite
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q90607|SEM3A_CHICK
Semaphorin-3A
Search

SEMA3A

0.97	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa

0.84	GO:0050919	negative chemotaxis
0.84	GO:1903045	neural crest cell migration involved in sympathetic nervous system development
0.84	GO:2001224	positive regulation of neuron migration
0.83	GO:1903375	facioacoustic ganglion development
0.82	GO:0021828	gonadotrophin-releasing hormone neuronal migration to the hypothalamus
0.82	GO:0036486	ventral trunk neural crest cell migration
0.82	GO:0097490	sympathetic neuron projection extension
0.82	GO:0097491	sympathetic neuron projection guidance
0.82	GO:0140059	dendrite arborization
0.82	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance

0.85	GO:0038191	neuropilin binding
0.81	GO:0045499	chemorepellent activity
0.81	GO:0030215	semaphorin receptor binding

0.71	GO:0005615	extracellular space
0.62	GO:0030424	axon
0.45	GO:0044297	cell body
0.45	GO:0030425	dendrite
0.30	GO:0016020	membrane

sp|Q90610|NEO1_CHICK
Neogenin (Fragment)
Search

NEO1

0.92

Neogenin

0.85	GO:0030513	positive regulation of BMP signaling pathway
0.81	GO:0007411	axon guidance
0.75	GO:0055072	iron ion homeostasis
0.42	GO:0001756	somitogenesis
0.42	GO:0001841	neural tube formation
0.37	GO:0007155	cell adhesion
0.36	GO:0048681	negative regulation of axon regeneration
0.36	GO:2001222	regulation of neuron migration
0.36	GO:0007520	myoblast fusion
0.35	GO:0050709	negative regulation of protein secretion

0.65	GO:0004872	receptor activity
0.58	GO:0039706	co-receptor binding
0.36	GO:0070700	BMP receptor binding
0.35	GO:0045296	cadherin binding
0.34	GO:0004871	signal transducer activity

0.67	GO:0005887	integral component of plasma membrane
0.49	GO:0005794	Golgi apparatus
0.49	GO:0005654	nucleoplasm
0.47	GO:0098797	plasma membrane protein complex
0.35	GO:0009986	cell surface
0.34	GO:0097708	intracellular vesicle

sp|Q90611|MMP2_CHICK
72 kDa type IV collagenase
Search

MMP2

0.94	Type IV collagenase

0.61	GO:0006508	proteolysis
0.42	GO:1904932	negative regulation of cartilage condensation
0.41	GO:1990314	cellular response to insulin-like growth factor stimulus
0.41	GO:0001957	intramembranous ossification
0.41	GO:0060346	bone trabecula formation
0.40	GO:0001955	blood vessel maturation
0.40	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.40	GO:0051895	negative regulation of focal adhesion assembly
0.40	GO:0030574	collagen catabolic process
0.40	GO:0060325	face morphogenesis

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding

0.74	GO:0031012	extracellular matrix
0.39	GO:0030017	sarcomere
0.38	GO:0005615	extracellular space
0.35	GO:0005739	mitochondrion
0.35	GO:0005886	plasma membrane

0.70

GO:0004222

sp|Q90615|ITA1_CHICK
Integrin alpha-1 (Fragment)
Search

0.67	Integrin alpha-1 (Fragment)

0.79	GO:0007229	integrin-mediated signaling pathway
0.72	GO:0007155	cell adhesion
0.56	GO:0032516	positive regulation of phosphoprotein phosphatase activity
0.55	GO:0045123	cellular extravasation
0.55	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.54	GO:0030593	neutrophil chemotaxis
0.51	GO:0008285	negative regulation of cell proliferation
0.38	GO:0043525	positive regulation of neuron apoptotic process
0.38	GO:0042311	vasodilation
0.38	GO:0000187	activation of MAPK activity

0.57	GO:0098639	collagen binding involved in cell-matrix adhesion
0.53	GO:0019903	protein phosphatase binding
0.37	GO:0038064	collagen receptor activity
0.36	GO:0005102	receptor binding
0.34	GO:0046872	metal ion binding
0.33	GO:0008168	methyltransferase activity
0.32	GO:0003676	nucleic acid binding

0.80	GO:0008305	integrin complex
0.53	GO:0045178	basal part of cell
0.52	GO:0005925	focal adhesion
0.52	GO:0009897	external side of plasma membrane
0.38	GO:0043204	perikaryon
0.38	GO:0001669	acrosomal vesicle
0.37	GO:0045121	membrane raft
0.37	GO:0043005	neuron projection
0.36	GO:0070062	extracellular exosome
0.34	GO:0005581	collagen trimer

0.33

GO:0008168

sp|Q90617|LAMP2_CHICK
Lysosome-associated membrane glycoprotein 2
Search

LAMP2

0.92	Lysosome-associated membrane glycoprotein 2

0.55	GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy
0.54	GO:1905146	lysosomal protein catabolic process
0.51	GO:0097352	autophagosome maturation
0.50	GO:0046716	muscle cell cellular homeostasis
0.49	GO:0031647	regulation of protein stability
0.47	GO:0009267	cellular response to starvation
0.35	GO:0006511	ubiquitin-dependent protein catabolic process

0.47	GO:0019904	protein domain specific binding
0.47	GO:0019899	enzyme binding

0.82	GO:0005765	lysosomal membrane
0.54	GO:0031088	platelet dense granule membrane
0.53	GO:0044754	autolysosome
0.53	GO:0097636	intrinsic component of autophagosome membrane
0.51	GO:0030670	phagocytic vesicle membrane
0.51	GO:0031166	integral component of vacuolar membrane
0.50	GO:0031902	late endosome membrane
0.50	GO:0070062	extracellular exosome
0.34	GO:0005886	plasma membrane

sp|Q90623|MYPT1_CHICK
Protein phosphatase 1 regulatory subunit 12A
Search

PPP1R12A

0.92	130 kDa regulatory subunit of myosin phosphatase (Fragment)

0.68	GO:0050790	regulation of catalytic activity
0.60	GO:0007165	signal transduction
0.57	GO:0035307	positive regulation of protein dephosphorylation
0.55	GO:0007098	centrosome cycle
0.54	GO:0046822	regulation of nucleocytoplasmic transport
0.54	GO:0035690	cellular response to drug
0.52	GO:0030155	regulation of cell adhesion
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.51	GO:0000278	mitotic cell cycle
0.50	GO:0044093	positive regulation of molecular function

0.78	GO:0019208	phosphatase regulator activity
0.76	GO:0019901	protein kinase binding
0.59	GO:0071889	14-3-3 protein binding
0.51	GO:0004857	enzyme inhibitor activity
0.34	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0004871	signal transducer activity
0.32	GO:0046982	protein heterodimerization activity

0.57	GO:0031672	A band
0.56	GO:0072357	PTW/PP1 phosphatase complex
0.55	GO:0030018	Z disc
0.53	GO:0000776	kinetochore
0.53	GO:0005813	centrosome
0.51	GO:0015629	actin cytoskeleton
0.48	GO:0005829	cytosol
0.37	GO:0005925	focal adhesion
0.34	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.34

EC:3.1.3.16

GO:0004721

sp|Q90625|ZBT17_CHICK
Zinc finger and BTB domain-containing protein 17 (Fragment)
Search

0.10	Zinc finger and BTB domain-containing protein 17 (Fragment)

0.49	GO:0007398	ectoderm development
0.49	GO:0071158	positive regulation of cell cycle arrest
0.49	GO:0001702	gastrulation with mouth forming second
0.49	GO:1903146	regulation of autophagy of mitochondrion
0.48	GO:1903955	positive regulation of protein targeting to mitochondrion
0.46	GO:0008285	negative regulation of cell proliferation
0.45	GO:0006366	transcription by RNA polymerase II
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0030097	hemopoiesis

0.51	GO:0003676	nucleic acid binding
0.50	GO:0001223	transcription coactivator binding
0.47	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.32	GO:0046872	metal ion binding

0.44	GO:0032993	protein-DNA complex
0.41	GO:0005634	nucleus
0.40	GO:0043234	protein complex

sp|Q90627|TRY1_CHICK
Trypsin I-P1
Search

0.44	Cationic trypsinogen

0.61	GO:0006508	proteolysis
0.50	GO:0007586	digestion
0.36	GO:0043542	endothelial cell migration
0.35	GO:0007584	response to nutrient
0.35	GO:0031000	response to caffeine
0.35	GO:0022617	extracellular matrix disassembly
0.34	GO:0030574	collagen catabolic process
0.34	GO:0035094	response to nicotine
0.33	GO:0051604	protein maturation
0.33	GO:0009235	cobalamin metabolic process

0.69	GO:0004252	serine-type endopeptidase activity
0.37	GO:0046872	metal ion binding
0.35	GO:0097655	serpin family protein binding
0.34	GO:0046982	protein heterodimerization activity

0.49	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:0097180	serine protease inhibitor complex
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|Q90628|TRY2_CHICK
Trypsin I-P38
Search

0.44	Cationic trypsinogen

0.61	GO:0006508	proteolysis
0.50	GO:0007586	digestion
0.36	GO:0007584	response to nutrient
0.35	GO:0031000	response to caffeine
0.35	GO:0022617	extracellular matrix disassembly
0.34	GO:0030574	collagen catabolic process
0.34	GO:0035094	response to nicotine
0.34	GO:0043542	endothelial cell migration
0.33	GO:0051604	protein maturation
0.33	GO:0009235	cobalamin metabolic process

0.69	GO:0004252	serine-type endopeptidase activity
0.37	GO:0046872	metal ion binding
0.35	GO:0097655	serpin family protein binding
0.34	GO:0046982	protein heterodimerization activity

0.49	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.35	GO:0097180	serine protease inhibitor complex
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|Q90629|TRY3_CHICK
Trypsin II-P29
Search

0.47	Pancreatic anionic trypsinogen

0.61	GO:0006508	proteolysis
0.52	GO:0007586	digestion
0.39	GO:0030574	collagen catabolic process
0.38	GO:0007584	response to nutrient
0.38	GO:0031000	response to caffeine
0.38	GO:0035094	response to nicotine
0.34	GO:0043542	endothelial cell migration
0.33	GO:0051604	protein maturation

0.69	GO:0004252	serine-type endopeptidase activity
0.38	GO:0005509	calcium ion binding
0.35	GO:0097655	serpin family protein binding
0.34	GO:0046982	protein heterodimerization activity

0.51	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:0097180	serine protease inhibitor complex
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|Q90631|KTN1_CHICK
Kinectin
Search

KTN1

0.73

Kinectin

0.74	GO:0007018	microtubule-based movement
0.54	GO:0015031	protein transport
0.33	GO:0043687	post-translational protein modification

0.85	GO:0019894	kinesin binding
0.53	GO:0045296	cadherin binding
0.32	GO:0003723	RNA binding

0.63	GO:0030176	integral component of endoplasmic reticulum membrane
0.33	GO:0005788	endoplasmic reticulum lumen
0.32	GO:0070382	exocytic vesicle
0.32	GO:0005887	integral component of plasma membrane

sp|Q90632|MOT3_CHICK
Monocarboxylate transporter 3
Search

SLC16A8

0.94	Monocarboxylate transporter 3

0.81	GO:0035873	lactate transmembrane transport
0.36	GO:0050900	leukocyte migration
0.35	GO:0006090	pyruvate metabolic process

0.81	GO:0015129	lactate transmembrane transporter activity
0.39	GO:0015293	symporter activity

0.67	GO:0005887	integral component of plasma membrane
0.36	GO:0031965	nuclear membrane

sp|Q90635|DPYL2_CHICK
Dihydropyrimidinase-related protein 2
Search

DPYSL2

0.95	Dihydropyrimidinase-related protein 2 isoform B

0.84	GO:0030516	regulation of axon extension
0.80	GO:0007411	axon guidance
0.78	GO:0007420	brain development
0.71	GO:0007010	cytoskeleton organization
0.41	GO:0014049	positive regulation of glutamate secretion
0.41	GO:0001975	response to amphetamine
0.40	GO:0042220	response to cocaine
0.40	GO:0021510	spinal cord development
0.40	GO:0016192	vesicle-mediated transport
0.40	GO:0097480	establishment of synaptic vesicle localization

0.74	GO:0008017	microtubule binding
0.65	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
0.44	GO:0019901	protein kinase binding
0.38	GO:0042802	identical protein binding

0.48	GO:0005737	cytoplasm
0.45	GO:0043209	myelin sheath
0.45	GO:0043025	neuronal cell body
0.45	GO:0030425	dendrite
0.45	GO:0030424	axon
0.40	GO:0005874	microtubule
0.40	GO:0043679	axon terminus
0.40	GO:0030426	growth cone
0.38	GO:0043227	membrane-bounded organelle
0.38	GO:0005886	plasma membrane

0.65

EC:3.5

GO:0016810

sp|Q90640|KIF4_CHICK
Chromosome-associated kinesin KIF4
Search

KIF4A

0.97	Kinesin family member 4

0.74	GO:0007018	microtubule-based movement
0.46	GO:0051256	mitotic spindle midzone assembly
0.44	GO:0000281	mitotic cytokinesis
0.37	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.36	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.35	GO:0030705	cytoskeleton-dependent intracellular transport
0.34	GO:0006629	lipid metabolic process
0.33	GO:0022008	neurogenesis
0.33	GO:0030030	cell projection organization

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0042623	ATPase activity, coupled
0.35	GO:0008889	glycerophosphodiester phosphodiesterase activity
0.35	GO:0003677	DNA binding

0.48	GO:0005871	kinesin complex
0.44	GO:0045171	intercellular bridge
0.42	GO:0005874	microtubule
0.42	GO:0030496	midbody
0.40	GO:0005654	nucleoplasm
0.37	GO:0005694	chromosome
0.37	GO:0016363	nuclear matrix
0.36	GO:0005829	cytosol
0.35	GO:1904115	axon cytoplasm
0.34	GO:0005819	spindle

0.35

EC:3.1.4.46

GO:0008889

sp|Q90641|IPKA_CHICK
cAMP-dependent protein kinase inhibitor alpha
Search

PKIA

0.97	cAMP-dependent protein kinase inhibitor alpha

0.81	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.63	GO:2000479	regulation of cAMP-dependent protein kinase activity
0.58	GO:0042308	negative regulation of protein import into nucleus
0.56	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.54	GO:0000122	negative regulation of transcription by RNA polymerase II
0.52	GO:0016310	phosphorylation

0.85	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.61	GO:0034236	protein kinase A catalytic subunit binding
0.54	GO:0016301	kinase activity

0.47	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm

sp|Q90643|IRF3_CHICK
Interferon regulatory factor 3
Search

IRF7

0.77	Interferon regulatory factor 3

0.60	GO:0045351	type I interferon biosynthetic process
0.59	GO:0060340	positive regulation of type I interferon-mediated signaling pathway
0.59	GO:0034127	regulation of MyD88-independent toll-like receptor signaling pathway
0.59	GO:0032607	interferon-alpha production
0.58	GO:0032608	interferon-beta production
0.58	GO:0032727	positive regulation of interferon-alpha production
0.58	GO:0032728	positive regulation of interferon-beta production
0.57	GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway
0.56	GO:0006351	transcription, DNA-templated
0.56	GO:0006355	regulation of transcription, DNA-templated

0.75	GO:0044212	transcription regulatory region DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.51	GO:1990837	sequence-specific double-stranded DNA binding
0.40	GO:0019904	protein domain specific binding
0.39	GO:0042803	protein homodimerization activity

0.60	GO:0005634	nucleus
0.49	GO:0005829	cytosol
0.47	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.34	GO:0005768	endosome
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.33	GO:0048471	perinuclear region of cytoplasm

sp|Q90647|VATA_CHICK
V-type proton ATPase catalytic subunit A
Search

ATP6V1A

0.91	ATPase H+ transporting V1 subunit A

0.75	GO:0015991	ATP hydrolysis coupled proton transport
0.64	GO:0036295	cellular response to increased oxygen levels
0.62	GO:0046034	ATP metabolic process
0.57	GO:0006875	cellular metal ion homeostasis
0.56	GO:0055072	iron ion homeostasis
0.40	GO:0055078	sodium ion homeostasis
0.39	GO:0030004	cellular monovalent inorganic cation homeostasis
0.39	GO:0055074	calcium ion homeostasis
0.39	GO:0072503	cellular divalent inorganic cation homeostasis

0.80	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.68	GO:0016324	apical plasma membrane
0.61	GO:0005902	microvillus
0.60	GO:0043209	myelin sheath
0.52	GO:0005829	cytosol
0.49	GO:0005765	lysosomal membrane
0.47	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q90655|AKR_CHICK
Homeobox protein AKR
Search

TGIF1

0.90	Homeobox protein AKR

0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.34	GO:1902679	negative regulation of RNA biosynthetic process
0.33	GO:0006351	transcription, DNA-templated

0.55	GO:0003677	DNA binding
0.36	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0001067	regulatory region nucleic acid binding

0.36	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

sp|Q90660|BIR_CHICK
Inhibitor of apoptosis protein
Search

BIRC2

0.90	Baculoviral IAP repeat-containing protein 2

0.74	GO:0042981	regulation of apoptotic process
0.60	GO:0060544	regulation of necroptotic process
0.57	GO:0060547	negative regulation of necrotic cell death
0.52	GO:0031398	positive regulation of protein ubiquitination
0.52	GO:0097340	inhibition of cysteine-type endopeptidase activity
0.52	GO:0043069	negative regulation of programmed cell death
0.52	GO:0012501	programmed cell death
0.52	GO:0016567	protein ubiquitination
0.51	GO:1902914	regulation of protein polyubiquitination
0.51	GO:1902525	regulation of protein monoubiquitination

0.52	GO:0004842	ubiquitin-protein transferase activity
0.52	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.52	GO:0098770	FBXO family protein binding
0.49	GO:0047485	protein N-terminus binding
0.47	GO:0043130	ubiquitin binding
0.46	GO:0003713	transcription coactivator activity
0.46	GO:0051087	chaperone binding
0.41	GO:0008270	zinc ion binding
0.37	GO:0042802	identical protein binding

0.50	GO:0035631	CD40 receptor complex
0.46	GO:0005634	nucleus
0.45	GO:0009898	cytoplasmic side of plasma membrane
0.41	GO:0098857	membrane microdomain
0.40	GO:0005829	cytosol
0.40	GO:0070013	intracellular organelle lumen
0.40	GO:0001741	XY body
0.37	GO:0044446	intracellular organelle part
0.37	GO:0043234	protein complex

0.52

GO:0004842

tr|Q90661|Q90661_CHICK
Synaptophysin IIa
Search

SYNPR

0.96	Synaptophysin IIa

0.48	GO:0048168	regulation of neuronal synaptic plasticity
0.42	GO:0048488	synaptic vesicle endocytosis
0.39	GO:0071310	cellular response to organic substance
0.34	GO:2000474	regulation of opioid receptor signaling pathway
0.34	GO:0045920	negative regulation of exocytosis
0.33	GO:0048499	synaptic vesicle membrane organization
0.33	GO:0016188	synaptic vesicle maturation

0.42	GO:0042169	SH2 domain binding
0.42	GO:0015485	cholesterol binding
0.40	GO:0042802	identical protein binding
0.33	GO:0003924	GTPase activity
0.33	GO:0051020	GTPase binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0043621	protein self-association
0.33	GO:0046914	transition metal ion binding
0.32	GO:0032555	purine ribonucleotide binding

0.82	GO:0008021	synaptic vesicle
0.52	GO:0099501	exocytic vesicle membrane
0.46	GO:0031301	integral component of organelle membrane
0.42	GO:0060076	excitatory synapse
0.42	GO:0043005	neuron projection
0.42	GO:0042734	presynaptic membrane
0.42	GO:0031594	neuromuscular junction
0.41	GO:0048786	presynaptic active zone
0.40	GO:0120038	plasma membrane bounded cell projection part
0.37	GO:0030054	cell junction

sp|Q90663|SEM3D_CHICK
Semaphorin-3D
Search

SEMA3D

0.97	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D

0.62	GO:0050919	negative chemotaxis
0.47	GO:0007399	nervous system development
0.47	GO:0001755	neural crest cell migration
0.46	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching
0.45	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.45	GO:0000904	cell morphogenesis involved in differentiation
0.44	GO:0008037	cell recognition
0.44	GO:0120036	plasma membrane bounded cell projection organization
0.44	GO:0060284	regulation of cell development
0.44	GO:0035290	trunk segmentation

0.64	GO:0038191	neuropilin binding
0.46	GO:0030215	semaphorin receptor binding
0.44	GO:0045499	chemorepellent activity

0.64	GO:0005615	extracellular space
0.39	GO:0044297	cell body
0.38	GO:0030424	axon
0.30	GO:0016020	membrane

sp|Q90665|SEM4D_CHICK
Semaphorin-4D (Fragment)
Search

0.56	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis
0.55	GO:0010693	negative regulation of alkaline phosphatase activity
0.55	GO:0070486	leukocyte aggregation
0.55	GO:0048672	positive regulation of collateral sprouting
0.54	GO:0043931	ossification involved in bone maturation
0.53	GO:0045668	negative regulation of osteoblast differentiation
0.53	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.52	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation
0.52	GO:0048814	regulation of dendrite morphogenesis
0.51	GO:0007162	negative regulation of cell adhesion

0.55	GO:0030215	semaphorin receptor binding
0.49	GO:0038191	neuropilin binding
0.46	GO:0004888	transmembrane signaling receptor activity
0.37	GO:0042802	identical protein binding

0.49	GO:0005615	extracellular space
0.45	GO:0005887	integral component of plasma membrane

sp|Q90667|NREP_CHICK
Neuronal regeneration-related protein
Search

NREP

0.97	Neuronal regeneration-related protein (Fragment)

0.84

GO:0017015

regulation of transforming growth factor beta receptor signaling pathway

sp|Q90669|AVR2A_CHICK
Activin receptor type-2A
Search

ACVR2A

0.74	Serine/threonine-protein kinase receptor

0.80	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.66	GO:0023014	signal transduction by protein phosphorylation
0.59	GO:0043084	penile erection
0.58	GO:0032927	positive regulation of activin receptor signaling pathway
0.58	GO:0042713	sperm ejaculation
0.57	GO:0060011	Sertoli cell proliferation
0.57	GO:0045648	positive regulation of erythrocyte differentiation
0.56	GO:0030501	positive regulation of bone mineralization
0.56	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.56	GO:0045669	positive regulation of osteoblast differentiation

0.81	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.79	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.58	GO:0048185	activin binding
0.58	GO:0034711	inhibin binding
0.56	GO:0015026	coreceptor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0043621	protein self-association
0.54	GO:0030165	PDZ domain binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.59	GO:0034673	inhibin-betaglycan-ActRII complex
0.54	GO:0043235	receptor complex
0.50	GO:0009986	cell surface
0.39	GO:0005737	cytoplasm
0.34	GO:0005887	integral component of plasma membrane
0.34	GO:1902554	serine/threonine protein kinase complex

0.81

GO:0004675

sp|Q90670|AVR2B_CHICK
Activin receptor type-2B
Search

ACVR2B

0.74	Serine/threonine-protein kinase receptor

0.80	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.66	GO:0023014	signal transduction by protein phosphorylation
0.54	GO:0032927	positive regulation of activin receptor signaling pathway
0.53	GO:0060836	lymphatic endothelial cell differentiation
0.53	GO:0048617	embryonic foregut morphogenesis
0.53	GO:0061298	retina vasculature development in camera-type eye
0.53	GO:0060841	venous blood vessel development
0.52	GO:0001946	lymphangiogenesis
0.52	GO:0030501	positive regulation of bone mineralization
0.52	GO:0001974	blood vessel remodeling

0.81	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.79	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0048185	activin binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.50	GO:0019838	growth factor binding
0.50	GO:0004712	protein serine/threonine/tyrosine kinase activity

0.49	GO:0043235	receptor complex
0.42	GO:0043234	protein complex
0.37	GO:0005737	cytoplasm
0.37	GO:0045178	basal part of cell
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.81

GO:0004675

sp|Q90673|PRLD1_CHICK
PRELI domain-containing protein 1, mitochondrial
Search

PRELID1

0.95	PRELI domain-containing protein 1, mitochondrial

0.55	GO:0010917	negative regulation of mitochondrial membrane potential
0.55	GO:1901857	positive regulation of cellular respiration
0.55	GO:2001140	positive regulation of phospholipid transport
0.55	GO:0070234	positive regulation of T cell apoptotic process
0.54	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.52	GO:0045580	regulation of T cell differentiation
0.52	GO:0015914	phospholipid transport
0.52	GO:0010950	positive regulation of endopeptidase activity
0.50	GO:0097035	regulation of membrane lipid distribution
0.38	GO:0006915	apoptotic process

0.58	GO:1990050	phosphatidic acid transporter activity
0.35	GO:0018024	histone-lysine N-methyltransferase activity
0.34	GO:0045028	G-protein coupled purinergic nucleotide receptor activity
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.79	GO:0005758	mitochondrial intermembrane space
0.46	GO:0005654	nucleoplasm
0.42	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.35

EC:2.1.1.43

GO:0018024

sp|Q90674|LSHR_CHICK
Lutropin-choriogonadotropic hormone receptor
Search

LHCGR

0.79	Lutropin-choriogonadotropic hormone receptor

0.81	GO:0042700	luteinizing hormone signaling pathway
0.64	GO:0001541	ovarian follicle development
0.57	GO:0071371	cellular response to gonadotropin stimulus
0.56	GO:0007190	activation of adenylate cyclase activity
0.56	GO:0046544	development of secondary male sexual characteristics
0.56	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process
0.54	GO:0022412	cellular process involved in reproduction in multicellular organism
0.54	GO:0090030	regulation of steroid hormone biosynthetic process
0.54	GO:0072520	seminiferous tubule development
0.54	GO:0060065	uterus development

0.81	GO:0004964	luteinizing hormone receptor activity
0.59	GO:0004963	follicle-stimulating hormone receptor activity
0.57	GO:0035472	choriogonadotropin hormone receptor activity
0.57	GO:0038106	choriogonadotropin hormone binding
0.43	GO:0008528	G-protein coupled peptide receptor activity
0.34	GO:0017046	peptide hormone binding
0.34	GO:0051117	ATPase binding
0.34	GO:0042803	protein homodimerization activity

0.52	GO:0005886	plasma membrane
0.37	GO:0005622	intracellular
0.35	GO:0009986	cell surface
0.34	GO:0031982	vesicle
0.34	GO:0012505	endomembrane system
0.34	GO:0043235	receptor complex
0.34	GO:0098552	side of membrane
0.33	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

sp|Q90678|PAFA_CHICK
Platelet-activating factor acetylhydrolase
Search

PLA2G7

0.92	Platelet-activating factor acetylhydrolase

0.70	GO:0016042	lipid catabolic process
0.57	GO:0034441	plasma lipoprotein particle oxidation
0.56	GO:0046469	platelet activating factor metabolic process
0.55	GO:0034374	low-density lipoprotein particle remodeling
0.54	GO:0090026	positive regulation of monocyte chemotaxis
0.50	GO:0034440	lipid oxidation
0.34	GO:0050729	positive regulation of inflammatory response
0.34	GO:0006954	inflammatory response

0.79	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity
0.56	GO:0047499	calcium-independent phospholipase A2 activity
0.49	GO:0005543	phospholipid binding

0.55	GO:0034362	low-density lipoprotein particle
0.33	GO:0005737	cytoplasm

0.79

EC:3.1.1.47

GO:0003847

sp|Q90679|THYN1_CHICK
Thymocyte nuclear protein 1
Search

THYN1

0.94	Thymocyte nuclear protein 1

0.39	GO:0042147	retrograde transport, endosome to Golgi
0.37	GO:0006886	intracellular protein transport
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.37	GO:0008565	protein transporter activity
0.33	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.39	GO:0030904	retromer complex
0.38	GO:0005768	endosome
0.37	GO:0005829	cytosol
0.35	GO:0000785	chromatin

sp|Q90683|ITF2_CHICK
Transcription factor 4 (Fragment)
Search

0.54	Transcription factor 4 (Fragment)

0.50	GO:0042118	endothelial cell activation
0.50	GO:0045666	positive regulation of neuron differentiation
0.49	GO:1900746	regulation of vascular endothelial growth factor signaling pathway
0.47	GO:0016525	negative regulation of angiogenesis
0.47	GO:0045944	positive regulation of transcription by RNA polymerase II
0.46	GO:0006367	transcription initiation from RNA polymerase II promoter
0.45	GO:0065004	protein-DNA complex assembly
0.45	GO:0000122	negative regulation of transcription by RNA polymerase II

0.67	GO:0046983	protein dimerization activity
0.52	GO:0001087	transcription factor activity, TFIIB-class binding
0.52	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting
0.51	GO:0001093	TFIIB-class transcription factor binding
0.50	GO:0070888	E-box binding
0.48	GO:0043621	protein self-association
0.47	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0003714	transcription corepressor activity
0.46	GO:0043425	bHLH transcription factor binding
0.45	GO:0003682	chromatin binding

0.47	GO:0005667	transcription factor complex
0.42	GO:0005634	nucleus
0.36	GO:0000785	chromatin
0.35	GO:0043233	organelle lumen
0.34	GO:0032993	protein-DNA complex
0.30	GO:0016020	membrane

sp|Q90686|CATK_CHICK
Cathepsin K
Search

CTSK

0.97	Cathepsin K (Pycnodysostosis)

0.59	GO:0006508	proteolysis
0.58	GO:0030574	collagen catabolic process
0.57	GO:1903146	regulation of autophagy of mitochondrion
0.57	GO:1903955	positive regulation of protein targeting to mitochondrion
0.52	GO:0044257	cellular protein catabolic process
0.42	GO:0060348	bone development
0.42	GO:0009612	response to mechanical stimulus
0.42	GO:0051216	cartilage development
0.40	GO:0001957	intramembranous ossification
0.40	GO:0045453	bone resorption

0.69	GO:0008234	cysteine-type peptidase activity
0.58	GO:0001968	fibronectin binding
0.57	GO:0043394	proteoglycan binding
0.55	GO:0005518	collagen binding
0.49	GO:0004175	endopeptidase activity
0.33	GO:0017171	serine hydrolase activity

0.53	GO:0005615	extracellular space
0.49	GO:0005654	nucleoplasm
0.48	GO:0005764	lysosome
0.36	GO:0031904	endosome lumen
0.35	GO:0005775	vacuolar lumen
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008234

sp|Q90687|PTN11_CHICK
Tyrosine-protein phosphatase non-receptor type 11
Search

PTPN11

0.60	Tyrosine-protein phosphatase non-receptor type

0.72	GO:0035335	peptidyl-tyrosine dephosphorylation
0.60	GO:0051463	negative regulation of cortisol secretion
0.59	GO:0060125	negative regulation of growth hormone secretion
0.59	GO:0061582	intestinal epithelial cell migration
0.59	GO:0033277	abortive mitotic cell cycle
0.58	GO:0036302	atrioventricular canal development
0.58	GO:2001275	positive regulation of glucose import in response to insulin stimulus
0.58	GO:0033629	negative regulation of cell adhesion mediated by integrin
0.57	GO:0060020	Bergmann glial cell differentiation
0.57	GO:0071364	cellular response to epidermal growth factor stimulus

0.73	GO:0004725	protein tyrosine phosphatase activity
0.57	GO:0051428	peptide hormone receptor binding
0.57	GO:0005158	insulin receptor binding
0.56	GO:0005070	SH3/SH2 adaptor activity
0.55	GO:0030971	receptor tyrosine kinase binding
0.52	GO:0050839	cell adhesion molecule binding
0.40	GO:0031748	D1 dopamine receptor binding
0.39	GO:0043274	phospholipase binding
0.39	GO:0043560	insulin receptor substrate binding
0.37	GO:0019904	protein domain specific binding

0.45	GO:0005737	cytoplasm
0.44	GO:0005634	nucleus
0.44	GO:0043234	protein complex
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.73	EC:3.1.3.48	GO:0004725
0.36	KEGG:R04545	GO:0046934

sp|Q90688|MYPC3_CHICK
Myosin-binding protein C, cardiac-type
Search

MYBPC3

0.91	Myosin-binding protein C, cardiac-type

0.55	GO:0071688	striated muscle myosin thick filament assembly
0.55	GO:0006941	striated muscle contraction
0.53	GO:0045214	sarcomere organization
0.53	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.50	GO:0044057	regulation of system process
0.49	GO:0060047	heart contraction
0.48	GO:0007015	actin filament organization
0.46	GO:0007155	cell adhesion
0.46	GO:1903115	regulation of actin filament-based movement
0.44	GO:0032781	positive regulation of ATPase activity

0.56	GO:0008307	structural constituent of muscle
0.55	GO:0097493	structural molecule activity conferring elasticity
0.55	GO:0051371	muscle alpha-actinin binding
0.54	GO:0032036	myosin heavy chain binding
0.50	GO:0051015	actin filament binding
0.47	GO:0042802	identical protein binding
0.44	GO:0001671	ATPase activator activity
0.41	GO:0031432	titin binding
0.38	GO:0005200	structural constituent of cytoskeleton
0.37	GO:0046872	metal ion binding

0.57	GO:0032982	myosin filament
0.57	GO:0005859	muscle myosin complex
0.55	GO:0031672	A band
0.54	GO:0097512	cardiac myofibril
0.52	GO:0030018	Z disc
0.51	GO:0036379	myofilament
0.37	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q90690|HAND2_CHICK
Heart- and neural crest derivatives-expressed protein 2
Search

HAND2

0.95	Heart- and neural crest derivatives-expressed protein 2

0.64	GO:0003219	cardiac right ventricle formation
0.61	GO:0060536	cartilage morphogenesis
0.61	GO:2000677	regulation of transcription regulatory region DNA binding
0.60	GO:0043392	negative regulation of DNA binding
0.60	GO:0001947	heart looping
0.58	GO:0043433	negative regulation of DNA binding transcription factor activity
0.58	GO:0042475	odontogenesis of dentin-containing tooth
0.58	GO:0060485	mesenchyme development
0.58	GO:2000764	positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis
0.58	GO:2000763	positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process

0.68	GO:0046983	protein dimerization activity
0.57	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0003680	AT DNA binding
0.53	GO:0042802	identical protein binding
0.53	GO:0008134	transcription factor binding
0.52	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.48	GO:0003713	transcription coactivator activity
0.48	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.43	GO:0019899	enzyme binding

0.54	GO:0005667	transcription factor complex
0.51	GO:0031981	nuclear lumen
0.48	GO:0000785	chromatin
0.36	GO:0005737	cytoplasm

sp|Q90691|HAND1_CHICK
Heart- and neural crest derivatives-expressed protein 1
Search

HAND1

0.97	Heart and neural crest derivatives expressed transcript 1

0.66	GO:0003219	cardiac right ventricle formation
0.63	GO:0060536	cartilage morphogenesis
0.62	GO:2000677	regulation of transcription regulatory region DNA binding
0.62	GO:0043392	negative regulation of DNA binding
0.61	GO:0001947	heart looping
0.60	GO:0003218	cardiac left ventricle formation
0.60	GO:0043433	negative regulation of DNA binding transcription factor activity
0.60	GO:0042475	odontogenesis of dentin-containing tooth
0.60	GO:0003144	embryonic heart tube formation
0.59	GO:0060485	mesenchyme development

0.67	GO:0046983	protein dimerization activity
0.59	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.59	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.58	GO:0043425	bHLH transcription factor binding
0.55	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.54	GO:0042802	identical protein binding
0.54	GO:0003713	transcription coactivator activity
0.49	GO:0003680	AT DNA binding
0.49	GO:0019899	enzyme binding
0.47	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.55	GO:0005667	transcription factor complex
0.52	GO:0031981	nuclear lumen
0.47	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0005737	cytoplasm

sp|Q90693|PTC1_CHICK
Protein patched homolog 1
Search

PTCH1

0.93	LOW QUALITY PROTEIN: protein patched homolog 1

0.60	GO:0021997	neural plate axis specification
0.60	GO:0007165	signal transduction
0.60	GO:0045879	negative regulation of smoothened signaling pathway
0.59	GO:0010157	response to chlorate
0.59	GO:0071397	cellular response to cholesterol
0.59	GO:0009957	epidermal cell fate specification
0.59	GO:0072203	cell proliferation involved in metanephros development
0.58	GO:0010875	positive regulation of cholesterol efflux
0.58	GO:0043616	keratinocyte proliferation
0.57	GO:0040015	negative regulation of multicellular organism growth

0.86	GO:0008158	hedgehog receptor activity
0.60	GO:0005119	smoothened binding
0.60	GO:0097108	hedgehog family protein binding
0.58	GO:0005113	patched binding
0.55	GO:0015485	cholesterol binding
0.55	GO:0030332	cyclin binding
0.54	GO:0008201	heparin binding
0.51	GO:0032403	protein complex binding
0.33	GO:0008270	zinc ion binding

0.55	GO:0005901	caveola
0.54	GO:0030496	midbody
0.53	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005929	cilium
0.49	GO:0005794	Golgi apparatus
0.42	GO:0044294	dendritic growth cone
0.41	GO:0044295	axonal growth cone
0.40	GO:0014069	postsynaptic density
0.36	GO:0005634	nucleus
0.35	GO:0030666	endocytic vesicle membrane

sp|Q90694|CDC42_CHICK
Cell division control protein 42 homolog
Search

CDC42

0.83	Cell division control protein 42

0.74	GO:0007264	small GTPase mediated signal transduction
0.59	GO:0051301	cell division
0.53	GO:0046847	filopodium assembly
0.53	GO:0038189	neuropilin signaling pathway
0.52	GO:0071338	positive regulation of hair follicle cell proliferation
0.52	GO:0051489	regulation of filopodium assembly
0.51	GO:0060684	epithelial-mesenchymal cell signaling
0.51	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis
0.51	GO:0120034	positive regulation of plasma membrane bounded cell projection assembly
0.51	GO:0048664	neuron fate determination

0.66	GO:0003924	GTPase activity
0.64	GO:0005525	GTP binding
0.52	GO:0051022	Rho GDP-dissociation inhibitor binding
0.51	GO:0032427	GBD domain binding
0.51	GO:0034191	apolipoprotein A-I receptor binding
0.50	GO:0030742	GTP-dependent protein binding
0.50	GO:0031996	thioesterase binding
0.47	GO:0019901	protein kinase binding
0.45	GO:0061630	ubiquitin protein ligase activity
0.44	GO:0042802	identical protein binding

0.49	GO:0031256	leading edge membrane
0.49	GO:0051233	spindle midzone
0.48	GO:0045335	phagocytic vesicle
0.48	GO:0030496	midbody
0.48	GO:0043197	dendritic spine
0.48	GO:0043209	myelin sheath
0.48	GO:0030175	filopodium
0.47	GO:0072686	mitotic spindle
0.47	GO:0045177	apical part of cell
0.47	GO:0000322	storage vacuole

0.34

GO:0004674

tr|Q90700|Q90700_CHICK
Calcium signal-modulating cyclophilin ligand
Search

CAMLG

0.97	Calcium signal-modulating cyclophilin ligand

0.55	GO:0001881	receptor recycling
0.54	GO:0007173	epidermal growth factor receptor signaling pathway
0.34	GO:0006952	defense response
0.34	GO:0016032	viral process

0.38

GO:0050839

cell adhesion molecule binding

0.52	GO:0005783	endoplasmic reticulum
0.30	GO:0044425	membrane part

sp|Q90701|TEAD3_CHICK
Transcriptional enhancer factor TEF-5
Search

TEAD3

0.97	Transcriptional enhancer factor TEF-5

0.81	GO:0035329	hippo signaling
0.67	GO:0045944	positive regulation of transcription by RNA polymerase II
0.53	GO:0006351	transcription, DNA-templated
0.45	GO:0048568	embryonic organ development
0.39	GO:0055059	asymmetric neuroblast division
0.38	GO:1902459	positive regulation of stem cell population maintenance
0.35	GO:0007565	female pregnancy

0.59	GO:0003700	DNA binding transcription factor activity
0.51	GO:0003677	DNA binding
0.46	GO:0001085	RNA polymerase II transcription factor binding
0.44	GO:0001067	regulatory region nucleic acid binding

0.56	GO:0005634	nucleus
0.43	GO:0005667	transcription factor complex
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|Q90703|NOS2_CHICK
Nitric oxide synthase, inducible
Search

NOS2

0.72	Nitric oxide synthase

0.84	GO:0006809	nitric oxide biosynthetic process
0.60	GO:0072604	interleukin-6 secretion
0.60	GO:0032310	prostaglandin secretion
0.60	GO:0072606	interleukin-8 secretion
0.60	GO:0018119	peptidyl-cysteine S-nitrosylation
0.58	GO:1900015	regulation of cytokine production involved in inflammatory response
0.55	GO:0042742	defense response to bacterium
0.54	GO:0071346	cellular response to interferon-gamma
0.54	GO:0050796	regulation of insulin secretion
0.54	GO:0042177	negative regulation of protein catabolic process

0.85	GO:0004517	nitric-oxide synthase activity
0.79	GO:0005516	calmodulin binding
0.70	GO:0010181	FMN binding
0.69	GO:0050661	NADP binding
0.65	GO:0050660	flavin adenine dinucleotide binding
0.63	GO:0020037	heme binding
0.62	GO:0005506	iron ion binding
0.58	GO:0034617	tetrahydrobiopterin binding
0.53	GO:0034618	arginine binding
0.50	GO:0042803	protein homodimerization activity

0.52	GO:0030863	cortical cytoskeleton
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005777	peroxisome
0.47	GO:0005829	cytosol
0.36	GO:0016529	sarcoplasmic reticulum
0.36	GO:0042383	sarcolemma
0.35	GO:0005901	caveola
0.35	GO:0030018	Z disc
0.35	GO:0005634	nucleus
0.35	GO:0045202	synapse

0.85

EC:1.14.13.39

GO:0004517

sp|Q90705|EF2_CHICK
Elongation factor 2
Search

EEF2

0.57	Eukaryotic translation elongation factor 2

0.65	GO:0006414	translational elongation
0.50	GO:0002244	hematopoietic progenitor cell differentiation
0.48	GO:0045727	positive regulation of translation
0.41	GO:0070887	cellular response to chemical stimulus
0.40	GO:0010033	response to organic substance
0.40	GO:0014009	glial cell proliferation
0.39	GO:0002931	response to ischemia
0.39	GO:0003009	skeletal muscle contraction
0.39	GO:0033273	response to vitamin
0.39	GO:0035914	skeletal muscle cell differentiation

0.66	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.64	GO:0003746	translation elongation factor activity
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0045296	cadherin binding
0.48	GO:0019901	protein kinase binding
0.39	GO:0002039	p53 binding
0.38	GO:0008097	5S rRNA binding

0.51	GO:0016235	aggresome
0.49	GO:0005844	polysome
0.44	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.38	GO:0045121	membrane raft
0.38	GO:0005634	nucleus
0.37	GO:0031012	extracellular matrix
0.37	GO:0070062	extracellular exosome
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0034774	secretory granule lumen

sp|Q90718|SRF_CHICK
Serum response factor (Fragment)
Search

SRF

0.91	Serum response factor (C-fos serum response element-binding transcription factor)

0.68	GO:0045944	positive regulation of transcription by RNA polymerase II
0.59	GO:0061145	lung smooth muscle development
0.59	GO:0060532	bronchus cartilage development
0.58	GO:0060947	cardiac vascular smooth muscle cell differentiation
0.58	GO:0060534	trachea cartilage development
0.58	GO:0022028	tangential migration from the subventricular zone to the olfactory bulb
0.58	GO:0003256	regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
0.58	GO:1900222	negative regulation of amyloid-beta clearance
0.58	GO:0090009	primitive streak formation
0.58	GO:0045059	positive thymic T cell selection

0.72	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.72	GO:0000987	proximal promoter sequence-specific DNA binding
0.68	GO:0046983	protein dimerization activity
0.57	GO:0070878	primary miRNA binding
0.55	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding
0.55	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.54	GO:0031490	chromatin DNA binding
0.53	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.52	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.51	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.49	GO:0000785	chromatin
0.47	GO:0070013	intracellular organelle lumen
0.39	GO:0005737	cytoplasm
0.35	GO:0005887	integral component of plasma membrane
0.34	GO:0031461	cullin-RING ubiquitin ligase complex
0.33	GO:0005856	cytoskeleton

sp|Q90722|FGF8_CHICK
Fibroblast growth factor 8
Search

FGF8

0.62	Fibroblast growth factor

0.82	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.54	GO:0030917	midbrain-hindbrain boundary development
0.53	GO:0030916	otic vesicle formation
0.53	GO:0030878	thyroid gland development
0.53	GO:0060037	pharyngeal system development
0.51	GO:0007492	endoderm development
0.51	GO:0048634	regulation of muscle organ development
0.51	GO:0003206	cardiac chamber morphogenesis
0.51	GO:0007498	mesoderm development

0.83	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.37	GO:0042056	chemoattractant activity
0.35	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0004713	protein tyrosine kinase activity

0.65	GO:0005576	extracellular region
0.41	GO:0005764	lysosome
0.36	GO:0009897	external side of plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

sp|Q90732|PRS4_CHICK
26S protease regulatory subunit 4
Search

PSMC1

0.85	26S proteasome regulatory subunit 4

0.81	GO:1901800	positive regulation of proteasomal protein catabolic process
0.70	GO:0030163	protein catabolic process
0.52	GO:0006508	proteolysis
0.49	GO:1901215	negative regulation of neuron death
0.48	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.46	GO:0034976	response to endoplasmic reticulum stress
0.46	GO:0010243	response to organonitrogen compound
0.45	GO:0043632	modification-dependent macromolecule catabolic process
0.39	GO:0044267	cellular protein metabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition

0.82	GO:0036402	proteasome-activating ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0008233	peptidase activity
0.48	GO:0017025	TBP-class protein binding
0.34	GO:0008568	microtubule-severing ATPase activity
0.33	GO:0003723	RNA binding
0.33	GO:0003887	DNA-directed DNA polymerase activity

0.55	GO:1905369	endopeptidase complex
0.49	GO:0005737	cytoplasm
0.47	GO:0043234	protein complex
0.46	GO:0031981	nuclear lumen
0.30	GO:0016020	membrane

0.50

GO:0008233

sp|Q90733|COT2_CHICK
COUP transcription factor 2
Search

NR2F2

0.82	Nuclear receptor subfamily 2 group F member 1-A

0.80	GO:0030522	intracellular receptor signaling pathway
0.79	GO:0043401	steroid hormone mediated signaling pathway
0.71	GO:0060838	lymphatic endothelial cell fate commitment
0.69	GO:0060850	regulation of transcription involved in cell fate commitment
0.62	GO:0001568	blood vessel development
0.61	GO:0009956	radial pattern formation
0.61	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity
0.60	GO:0001937	negative regulation of endothelial cell proliferation
0.60	GO:0010596	negative regulation of endothelial cell migration
0.60	GO:0000122	negative regulation of transcription by RNA polymerase II

0.82	GO:0004879	nuclear receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0001972	retinoic acid binding
0.61	GO:0008270	zinc ion binding
0.54	GO:0042803	protein homodimerization activity
0.45	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.43	GO:0001012	RNA polymerase II regulatory region DNA binding
0.42	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.53	GO:0005829	cytosol
0.53	GO:0070013	intracellular organelle lumen
0.47	GO:0044446	intracellular organelle part

sp|Q90734|ACTN4_CHICK
Alpha-actinin-4
Search

ACTN4

0.66	Eukaryotic translation initiation factor 3 subunit K

0.64	GO:0051017	actin filament bundle assembly
0.61	GO:0051764	actin crosslink formation
0.54	GO:1902396	protein localization to bicellular tight junction
0.54	GO:0048741	skeletal muscle fiber development
0.54	GO:0035357	peroxisome proliferator activated receptor signaling pathway
0.53	GO:0045214	sarcomere organization
0.53	GO:0034329	cell junction assembly
0.53	GO:0045216	cell-cell junction organization
0.53	GO:0051271	negative regulation of cellular component movement
0.53	GO:0048549	positive regulation of pinocytosis

0.73	GO:0003779	actin binding
0.69	GO:0005509	calcium ion binding
0.59	GO:0032403	protein complex binding
0.57	GO:0017166	vinculin binding
0.56	GO:0042803	protein homodimerization activity
0.55	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.55	GO:0044325	ion channel binding
0.54	GO:0051393	alpha-actinin binding
0.52	GO:0042974	retinoic acid receptor binding
0.50	GO:0031490	chromatin DNA binding

0.62	GO:0097517	contractile actin filament bundle
0.61	GO:0042641	actomyosin
0.59	GO:0044449	contractile fiber part
0.58	GO:0030863	cortical cytoskeleton
0.56	GO:0005911	cell-cell junction
0.55	GO:0120025	plasma membrane bounded cell projection
0.55	GO:0097433	dense body
0.54	GO:0005903	brush border
0.53	GO:0005925	focal adhesion
0.53	GO:0016328	lateral plasma membrane

sp|Q90738|AFAP1_CHICK
Actin filament-associated protein 1
Search

AFAP1

0.97	Actin filament-associated protein 1

0.75	GO:0051493	regulation of cytoskeleton organization
0.69	GO:0009966	regulation of signal transduction
0.37	GO:0018109	peptidyl-arginine phosphorylation
0.35	GO:0071260	cellular response to mechanical stimulus
0.35	GO:0018108	peptidyl-tyrosine phosphorylation
0.33	GO:0007165	signal transduction

0.38	GO:0003779	actin binding
0.38	GO:0017124	SH3 domain binding
0.38	GO:0042169	SH2 domain binding
0.32	GO:0046872	metal ion binding

0.52	GO:0005925	focal adhesion
0.49	GO:0015629	actin cytoskeleton
0.46	GO:0005829	cytosol
0.34	GO:0099513	polymeric cytoskeletal fiber
0.33	GO:0005886	plasma membrane

tr|Q90743|Q90743_CHICK
Amyloid protein
Search

IAPP

0.94	Islet amyloid polypeptide

0.76	GO:0010469	regulation of receptor activity
0.54	GO:0045779	negative regulation of bone resorption
0.52	GO:0019233	sensory perception of pain
0.49	GO:0045596	negative regulation of cell differentiation
0.39	GO:0097646	calcitonin family receptor signaling pathway
0.39	GO:0038042	dimeric G-protein coupled receptor signaling pathway
0.38	GO:0007631	feeding behavior
0.38	GO:0055074	calcium ion homeostasis
0.36	GO:0030816	positive regulation of cAMP metabolic process
0.36	GO:0072503	cellular divalent inorganic cation homeostasis

0.79	GO:0005179	hormone activity
0.43	GO:0042802	identical protein binding
0.35	GO:0031716	calcitonin receptor binding
0.34	GO:0001540	amyloid-beta binding
0.33	GO:0032403	protein complex binding

0.66	GO:0005576	extracellular region
0.50	GO:0043025	neuronal cell body
0.35	GO:0043195	terminal bouton
0.34	GO:0016234	inclusion body
0.34	GO:0030141	secretory granule
0.33	GO:0005829	cytosol
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q90744|NAGAB_CHICK
Alpha-N-acetylgalactosaminidase
Search

NAGA

0.78	Alpha-N-acetylgalactosaminidase

0.60	GO:0005975	carbohydrate metabolic process
0.56	GO:0019377	glycolipid catabolic process
0.48	GO:0016139	glycoside catabolic process
0.47	GO:0006677	glycosylceramide metabolic process
0.47	GO:0046514	ceramide catabolic process

0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.50	GO:0042803	protein homodimerization activity

0.39	GO:0005764	lysosome
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.66

GO:0004553

sp|Q90751|BMP2_CHICK
Bone morphogenetic protein 2 (Fragment)
Search

BMP2

0.71	Bone morphogenetic protein 2

0.74	GO:0010469	regulation of receptor activity
0.63	GO:0003134	endodermal-mesodermal cell signaling involved in heart induction
0.63	GO:0051042	negative regulation of calcium-independent cell-cell adhesion
0.62	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development
0.62	GO:0035630	bone mineralization involved in bone maturation
0.61	GO:2000726	negative regulation of cardiac muscle cell differentiation
0.61	GO:0032345	negative regulation of aldosterone metabolic process
0.61	GO:2000065	negative regulation of cortisol biosynthetic process
0.61	GO:0060804	positive regulation of Wnt signaling pathway by BMP signaling pathway
0.61	GO:0032347	regulation of aldosterone biosynthetic process

0.77	GO:0008083	growth factor activity
0.62	GO:0070700	BMP receptor binding
0.60	GO:0039706	co-receptor binding
0.58	GO:0019211	phosphatase activator activity
0.58	GO:0046332	SMAD binding
0.58	GO:0004745	retinol dehydrogenase activity
0.52	GO:0046982	protein heterodimerization activity
0.48	GO:0005160	transforming growth factor beta receptor binding
0.47	GO:0005125	cytokine activity
0.34	GO:0019904	protein domain specific binding

0.65	GO:0005576	extracellular region
0.61	GO:0070724	BMP receptor complex
0.54	GO:0009986	cell surface
0.43	GO:0043227	membrane-bounded organelle
0.41	GO:0043229	intracellular organelle
0.33	GO:0043234	protein complex
0.32	GO:0005737	cytoplasm

0.58

EC:1.1.1.105

GO:0004745

sp|Q90752|BMP4_CHICK
Bone morphogenetic protein 4
Search

BMP4

0.79	Bone morphogenetic protein 4

0.74	GO:0010469	regulation of receptor activity
0.60	GO:0048392	intermediate mesodermal cell differentiation
0.60	GO:0071893	BMP signaling pathway involved in nephric duct formation
0.60	GO:0061155	pulmonary artery endothelial tube morphogenesis
0.60	GO:2000005	negative regulation of metanephric S-shaped body morphogenesis
0.60	GO:2000007	negative regulation of metanephric comma-shaped body morphogenesis
0.60	GO:0055018	regulation of cardiac muscle fiber development
0.60	GO:0072200	negative regulation of mesenchymal cell proliferation involved in ureter development
0.60	GO:0035844	cloaca development
0.60	GO:0072100	specification of ureteric bud anterior/posterior symmetry

0.77	GO:0008083	growth factor activity
0.60	GO:0070700	BMP receptor binding
0.57	GO:0039706	co-receptor binding
0.57	GO:0042056	chemoattractant activity
0.55	GO:0005125	cytokine activity
0.52	GO:0008201	heparin binding
0.46	GO:0005160	transforming growth factor beta receptor binding
0.34	GO:0042803	protein homodimerization activity

0.65	GO:0005576	extracellular region
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0031982	vesicle

sp|Q90762|CADH6_CHICK
Cadherin-6
Search

CDH6

0.96	Kidney cadherin

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.52	GO:0007219	Notch signaling pathway
0.36	GO:0034332	adherens junction organization
0.36	GO:0007416	synapse assembly
0.35	GO:0099560	synaptic membrane adhesion
0.35	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.34	GO:0008585	female gonad development

0.70	GO:0005509	calcium ion binding
0.36	GO:0098641	cadherin binding involved in cell-cell adhesion
0.36	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.37	GO:0098686	hippocampal mossy fiber to CA3 synapse
0.36	GO:0070062	extracellular exosome
0.35	GO:0030425	dendrite
0.35	GO:0030424	axon
0.34	GO:0098793	presynapse
0.34	GO:0098794	postsynapse
0.30	GO:0016021	integral component of membrane

sp|Q90763|CADH7_CHICK
Cadherin-7
Search

CDH7

0.97	Cadherin-7 type II

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.41	GO:0036032	neural crest cell delamination
0.40	GO:0009790	embryo development
0.39	GO:0048731	system development
0.39	GO:0072175	epithelial tube formation
0.37	GO:0030154	cell differentiation
0.35	GO:0098743	cell aggregation
0.35	GO:0034332	adherens junction organization
0.35	GO:0060173	limb development
0.35	GO:0061448	connective tissue development

0.70

GO:0005509

calcium ion binding

0.56	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q90771|Q90771_CHICK
Cyclin-dependent kinase
Search

CDK6

0.97	Cell division protein kinase 6

0.76	GO:0043697	cell dedifferentiation
0.67	GO:0042127	regulation of cell proliferation
0.65	GO:0051726	regulation of cell cycle
0.61	GO:0006468	protein phosphorylation
0.61	GO:1904628	cellular response to phorbol 13-acetate 12-myristate
0.59	GO:0007049	cell cycle
0.57	GO:0045656	negative regulation of monocyte differentiation
0.57	GO:2000773	negative regulation of cellular senescence
0.56	GO:0003323	type B pancreatic cell development
0.55	GO:0045668	negative regulation of osteoblast differentiation

0.74	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.58	GO:0030332	cyclin binding
0.58	GO:0098770	FBXO family protein binding
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0008144	drug binding
0.35	GO:0032403	protein complex binding
0.34	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.33	GO:0005509	calcium ion binding

0.59	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.53	GO:0001726	ruffle
0.51	GO:0005813	centrosome
0.49	GO:0005829	cytosol
0.49	GO:0031981	nuclear lumen
0.43	GO:0005923	bicellular tight junction
0.43	GO:0031965	nuclear membrane
0.41	GO:0005667	transcription factor complex
0.40	GO:0000785	chromatin
0.35	GO:0048471	perinuclear region of cytoplasm

0.74

EC:2.7.11.22

GO:0004693

sp|Q90773|CEPU1_CHICK
Protein CEPU-1
Search

NTM

0.87	Opioid binding protein/cell adhesion molecule like

0.66	GO:0007155	cell adhesion
0.52	GO:0006501	C-terminal protein lipidation
0.51	GO:0048699	generation of neurons
0.49	GO:0008037	cell recognition
0.47	GO:0048468	cell development
0.46	GO:0032355	response to estradiol
0.45	GO:0021549	cerebellum development
0.45	GO:0031345	negative regulation of cell projection organization
0.44	GO:0051961	negative regulation of nervous system development
0.44	GO:0010721	negative regulation of cell development

0.42

GO:0005515

protein binding

0.72	GO:0031225	anchored component of membrane
0.52	GO:0005886	plasma membrane
0.50	GO:0005615	extracellular space
0.48	GO:1903561	extracellular vesicle
0.46	GO:0060076	excitatory synapse
0.44	GO:0030424	axon
0.44	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0009986	cell surface

sp|Q90788|NKX25_CHICK
Homeobox protein Nkx-2.5
Search

NKX2-5

0.97	Cardiac homeobox transcription factor

0.83	GO:1903779	regulation of cardiac conduction
0.80	GO:0060048	cardiac muscle contraction
0.76	GO:0007507	heart development
0.67	GO:0006357	regulation of transcription by RNA polymerase II
0.62	GO:0060037	pharyngeal system development
0.61	GO:0014855	striated muscle cell proliferation
0.59	GO:0014706	striated muscle tissue development
0.59	GO:0035265	organ growth
0.59	GO:0051146	striated muscle cell differentiation
0.58	GO:0010667	negative regulation of cardiac muscle cell apoptotic process

0.65	GO:0043565	sequence-specific DNA binding
0.59	GO:0003700	DNA binding transcription factor activity
0.55	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003682	chromatin binding
0.52	GO:0001104	RNA polymerase II transcription cofactor activity
0.51	GO:0003690	double-stranded DNA binding
0.50	GO:0042803	protein homodimerization activity
0.50	GO:0046982	protein heterodimerization activity
0.50	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.50	GO:0032993	protein-DNA complex
0.43	GO:0044446	intracellular organelle part
0.38	GO:0005737	cytoplasm
0.34	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q90805|CNG1_CHICK
Cyclic nucleotide-gated channel cone photoreceptor subunit alpha
Search

CNGA3

0.94	Cyclic nucleotide-gated channel cone photoreceptor subunit alpha

0.60	GO:0034220	ion transmembrane transport
0.53	GO:0071804	cellular potassium ion transport
0.50	GO:0007601	visual perception
0.45	GO:0042391	regulation of membrane potential
0.42	GO:0032026	response to magnesium ion
0.41	GO:0051591	response to cAMP
0.41	GO:0046549	retinal cone cell development
0.41	GO:0031960	response to corticosteroid
0.36	GO:0007165	signal transduction
0.35	GO:0051480	regulation of cytosolic calcium ion concentration

0.70	GO:0005216	ion channel activity
0.60	GO:0022836	gated channel activity
0.54	GO:0030553	cGMP binding
0.53	GO:0015079	potassium ion transmembrane transporter activity
0.40	GO:0008022	protein C-terminus binding
0.36	GO:0004871	signal transducer activity
0.35	GO:0030552	cAMP binding
0.34	GO:0015085	calcium ion transmembrane transporter activity

0.45	GO:1902495	transmembrane transporter complex
0.44	GO:0042622	photoreceptor outer segment membrane
0.42	GO:0005887	integral component of plasma membrane
0.41	GO:0043204	perikaryon
0.40	GO:0030425	dendrite
0.34	GO:0043195	terminal bouton
0.34	GO:0005737	cytoplasm

tr|Q90807|Q90807_CHICK
Olfactory receptor (Fragment)
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.54	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q90812|CRFR1_CHICK
Corticotropin-releasing factor receptor 1
Search

CRHR1

0.94	Corticotrophin-releasing factor type 1 alpha receptor

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.50	GO:0051458	corticotropin secretion
0.49	GO:2000852	regulation of corticosterone secretion
0.49	GO:0071376	cellular response to corticotropin-releasing hormone stimulus
0.46	GO:0019933	cAMP-mediated signaling
0.44	GO:0051867	general adaptation syndrome, behavioral process
0.43	GO:0030325	adrenal gland development
0.43	GO:0042596	fear response
0.43	GO:0048149	behavioral response to ethanol

0.72	GO:0004930	G-protein coupled receptor activity
0.41	GO:0043404	corticotropin-releasing hormone receptor activity
0.39	GO:0051424	corticotropin-releasing hormone binding
0.39	GO:0001965	G-protein alpha-subunit binding
0.37	GO:0032403	protein complex binding

0.48	GO:0005886	plasma membrane
0.40	GO:0005768	endosome
0.38	GO:0043025	neuronal cell body
0.38	GO:0030425	dendrite
0.38	GO:0045177	apical part of cell
0.38	GO:0005802	trans-Golgi network
0.36	GO:0044309	neuron spine
0.35	GO:0098794	postsynapse
0.30	GO:0016021	integral component of membrane

tr|Q90813|Q90813_CHICK
Ch-runtB2
Search

RUNX1

0.88	Runt-related transcription factor

0.65	GO:0045893	positive regulation of transcription, DNA-templated
0.55	GO:0030854	positive regulation of granulocyte differentiation
0.53	GO:0032743	positive regulation of interleukin-2 production
0.53	GO:0006351	transcription, DNA-templated
0.51	GO:0030097	hemopoiesis
0.47	GO:0006357	regulation of transcription by RNA polymerase II
0.47	GO:0002062	chondrocyte differentiation
0.43	GO:0001503	ossification
0.41	GO:0030182	neuron differentiation
0.40	GO:0009953	dorsal/ventral pattern formation

0.60	GO:0003700	DNA binding transcription factor activity
0.55	GO:0030554	adenyl nucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0042809	vitamin D receptor binding
0.36	GO:0070491	repressing transcription factor binding
0.36	GO:0042803	protein homodimerization activity

0.61	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.45	GO:0070013	intracellular organelle lumen
0.41	GO:0044446	intracellular organelle part
0.35	GO:0005604	basement membrane
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q90826|CCL4_CHICK
C-C motif chemokine 4 homolog
Search

0.74	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.71	GO:0010469	regulation of receptor activity
0.55	GO:0070098	chemokine-mediated signaling pathway
0.54	GO:0006954	inflammatory response
0.50	GO:0097530	granulocyte migration
0.49	GO:0071347	cellular response to interleukin-1
0.49	GO:0071356	cellular response to tumor necrosis factor
0.48	GO:0071674	mononuclear cell migration
0.47	GO:0009615	response to virus

0.84	GO:0008009	chemokine activity
0.58	GO:0048020	CCR chemokine receptor binding
0.44	GO:0016004	phospholipase activator activity
0.44	GO:0042056	chemoattractant activity
0.42	GO:0046817	chemokine receptor antagonist activity
0.41	GO:0030298	receptor signaling protein tyrosine kinase activator activity
0.40	GO:0043621	protein self-association
0.39	GO:0004435	phosphatidylinositol phospholipase C activity
0.39	GO:0042802	identical protein binding
0.38	GO:0004698	calcium-dependent protein kinase C activity

0.70	GO:0005615	extracellular space
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.39	EC:3.1.4.11	GO:0004435
0.39	KEGG:R03435	GO:0004435

sp|Q90827|NEL_CHICK
Protein NEL
Search

NELL2

0.97	Neural EGFL like 2

0.70

GO:0005509

calcium ion binding

0.30	GO:0031224	intrinsic component of membrane
0.30	GO:0005623	cell

sp|Q90828|DC1L1_CHICK
Cytoplasmic dynein 1 light intermediate chain 1
Search

DYNC1LI1

0.94	Cytoplasmic dynein light-intermediate chain 1

0.73	GO:0007018	microtubule-based movement
0.59	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint
0.47	GO:0000226	microtubule cytoskeleton organization
0.42	GO:0051642	centrosome localization
0.39	GO:0009794	regulation of mitotic cell cycle, embryonic
0.39	GO:0070507	regulation of microtubule cytoskeleton organization
0.38	GO:0090235	regulation of metaphase plate congression
0.36	GO:0051301	cell division
0.36	GO:0007049	cell cycle
0.36	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II

0.73	GO:0003777	microtubule motor activity
0.60	GO:0045504	dynein heavy chain binding
0.57	GO:0019003	GDP binding
0.35	GO:0005525	GTP binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0003723	RNA binding

0.81	GO:0005868	cytoplasmic dynein complex
0.56	GO:0005813	centrosome
0.54	GO:0000922	spindle pole
0.54	GO:0000776	kinetochore
0.38	GO:0005874	microtubule
0.38	GO:0000779	condensed chromosome, centromeric region
0.36	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0005770	late endosome
0.35	GO:0005764	lysosome
0.34	GO:0005829	cytosol

sp|Q90830|CRTAP_CHICK
Cartilage-associated protein
Search

CRTAP

0.96	Putative membrane-associated proteoglycan leprecan

0.86	GO:0018400	peptidyl-proline hydroxylation to 3-hydroxy-L-proline
0.56	GO:1901874	negative regulation of post-translational protein modification
0.51	GO:0050821	protein stabilization
0.49	GO:0007283	spermatogenesis
0.47	GO:0061077	chaperone-mediated protein folding
0.32	GO:0055114	oxidation-reduction process

0.46	GO:0032403	protein complex binding
0.33	GO:0031418	L-ascorbic acid binding
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0005506	iron ion binding

0.69	GO:0005783	endoplasmic reticulum
0.48	GO:0005615	extracellular space
0.39	GO:0032991	macromolecular complex
0.37	GO:0005578	proteinaceous extracellular matrix
0.33	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016705

sp|Q90835|EF1A_CHICK
Elongation factor 1-alpha 1
Search

EEF1A1

0.45	Translation elongation factor EF-1 subunit alpha

0.68	GO:0006414	translational elongation
0.51	GO:0071364	cellular response to epidermal growth factor stimulus
0.35	GO:1904714	regulation of chaperone-mediated autophagy
0.35	GO:1903427	negative regulation of reactive oxygen species biosynthetic process
0.35	GO:1990090	cellular response to nerve growth factor stimulus
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0010976	positive regulation of neuron projection development
0.34	GO:0035690	cellular response to drug
0.34	GO:0007568	aging
0.34	GO:0010942	positive regulation of cell death

0.69	GO:0003746	translation elongation factor activity
0.66	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0019901	protein kinase binding
0.46	GO:0005516	calmodulin binding
0.43	GO:0000049	tRNA binding
0.34	GO:0003729	mRNA binding

0.49	GO:0032587	ruffle membrane
0.48	GO:0005737	cytoplasm
0.47	GO:0043209	myelin sheath
0.46	GO:0005730	nucleolus
0.45	GO:0015629	actin cytoskeleton
0.43	GO:0044430	cytoskeletal part
0.37	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0097708	intracellular vesicle

sp|Q90837|ERG_CHICK
Transcriptional regulator Erg
Search

ERG

0.88	Transcriptional regulator Erg

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:2000504	positive regulation of blood vessel remodeling
0.48	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation
0.46	GO:0003197	endocardial cushion development
0.43	GO:0016477	cell migration
0.42	GO:1902680	positive regulation of RNA biosynthetic process
0.36	GO:0060217	hemangioblast cell differentiation
0.36	GO:0008283	cell proliferation

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.43	GO:0001012	RNA polymerase II regulatory region DNA binding
0.43	GO:0003682	chromatin binding
0.42	GO:0003690	double-stranded DNA binding
0.36	GO:0005515	protein binding
0.34	GO:0004871	signal transducer activity

0.61	GO:0005634	nucleus
0.39	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0005737	cytoplasm

tr|Q90838|Q90838_CHICK
Leucine zipper protein
Search

CAVIN1

0.97	Polymerase I and transcript release factor

0.84	GO:0006363	termination of RNA polymerase I transcription
0.58	GO:0006361	transcription initiation from RNA polymerase I promoter
0.58	GO:0009303	rRNA transcription
0.55	GO:2000147	positive regulation of cell motility
0.42	GO:0097320	plasma membrane tubulation
0.41	GO:0030903	notochord development
0.36	GO:2001141	regulation of RNA biosynthetic process
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.35	GO:0007165	signal transduction

0.59	GO:0042134	rRNA primary transcript binding
0.52	GO:0042802	identical protein binding
0.43	GO:0008307	structural constituent of muscle
0.42	GO:0001786	phosphatidylserine binding
0.38	GO:0005080	protein kinase C binding
0.35	GO:0004871	signal transducer activity
0.35	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003677	DNA binding

0.83	GO:0005901	caveola
0.48	GO:0005634	nucleus
0.45	GO:0005739	mitochondrion
0.45	GO:0043234	protein complex
0.40	GO:0005829	cytosol
0.40	GO:0015629	actin cytoskeleton
0.39	GO:0043233	organelle lumen
0.37	GO:0044446	intracellular organelle part
0.36	GO:0005783	endoplasmic reticulum

sp|Q90839|DKK3_CHICK
Dickkopf-related protein 3
Search

DKK3

0.97	Dickkopf WNT signaling pathway inhibitor 3

0.82	GO:0030178	negative regulation of Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.40	GO:2000065	negative regulation of cortisol biosynthetic process
0.40	GO:0032345	negative regulation of aldosterone metabolic process
0.40	GO:0032347	regulation of aldosterone biosynthetic process
0.38	GO:0060828	regulation of canonical Wnt signaling pathway
0.38	GO:0016055	Wnt signaling pathway
0.37	GO:0031647	regulation of protein stability
0.37	GO:0045892	negative regulation of transcription, DNA-templated
0.36	GO:1902612	regulation of anti-Mullerian hormone signaling pathway

0.66

GO:0005576

extracellular region

sp|Q90844|FST_CHICK
Follistatin
Search

FST

0.96	Follistatin a

0.85	GO:0032926	negative regulation of activin receptor signaling pathway
0.84	GO:0051798	positive regulation of hair follicle development
0.80	GO:0002244	hematopoietic progenitor cell differentiation
0.73	GO:0000122	negative regulation of transcription by RNA polymerase II
0.44	GO:0045596	negative regulation of cell differentiation
0.43	GO:0043616	keratinocyte proliferation
0.43	GO:0001501	skeletal system development
0.43	GO:0031069	hair follicle morphogenesis
0.43	GO:0007389	pattern specification process
0.43	GO:0007276	gamete generation

0.85	GO:0048185	activin binding
0.48	GO:0043395	heparan sulfate proteoglycan binding
0.36	GO:0016651	oxidoreductase activity, acting on NAD(P)H
0.36	GO:0004871	signal transducer activity

0.49	GO:0005576	extracellular region
0.37	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm

0.36

EC:1.6

GO:0016651

sp|Q90845|GBRA6_CHICK
Gamma-aminobutyric acid receptor subunit alpha-6
Search

GABRA6

0.97	Gamma-aminobutyric acid receptor subunit alpha-6

0.83	GO:0007214	gamma-aminobutyric acid signaling pathway
0.74	GO:0006821	chloride transport
0.60	GO:0034220	ion transmembrane transport
0.50	GO:2001023	regulation of response to drug
0.48	GO:0007417	central nervous system development
0.35	GO:0051932	synaptic transmission, GABAergic
0.35	GO:0051291	protein heterooligomerization

0.84	GO:0004890	GABA-A receptor activity
0.75	GO:0005230	extracellular ligand-gated ion channel activity
0.41	GO:0005254	chloride channel activity
0.39	GO:0008503	benzodiazepine receptor activity
0.35	GO:0099095	ligand-gated anion channel activity
0.34	GO:0022835	transmitter-gated channel activity
0.32	GO:0008144	drug binding

0.55	GO:0005886	plasma membrane
0.51	GO:1902711	GABA-A receptor complex
0.42	GO:0034707	chloride channel complex
0.41	GO:0098794	postsynapse
0.40	GO:0030054	cell junction
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite
0.34	GO:0098793	presynapse

sp|Q90850|HIC1_CHICK
Hypermethylated in cancer 1 protein (Fragment)
Search

HIC1

0.74	Hypermethylated in cancer 1 like

0.73	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.67	GO:0000122	negative regulation of transcription by RNA polymerase II
0.40	GO:0007275	multicellular organism development
0.38	GO:0006351	transcription, DNA-templated
0.36	GO:0030178	negative regulation of Wnt signaling pathway
0.36	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator
0.34	GO:0016055	Wnt signaling pathway

0.54	GO:0003700	DNA binding transcription factor activity
0.51	GO:0003676	nucleic acid binding
0.40	GO:0046872	metal ion binding
0.36	GO:0042826	histone deacetylase binding
0.33	GO:0008022	protein C-terminus binding

0.42	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle
0.34	GO:0043233	organelle lumen
0.33	GO:0043228	non-membrane-bounded organelle

sp|Q90854|KCNJ3_CHICK
G protein-activated inward rectifier potassium channel 1
Search

KCNJ3

0.97	G protein-activated inward rectifier potassium channel 1

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.55	GO:0099587	inorganic ion import across plasma membrane
0.40	GO:0051602	response to electrical stimulus
0.36	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential
0.36	GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential
0.35	GO:0086091	regulation of heart rate by cardiac conduction
0.33	GO:0015074	DNA integration

0.86	GO:0015467	G-protein activated inward rectifier potassium channel activity
0.36	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
0.36	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
0.35	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.51	GO:0008076	voltage-gated potassium channel complex
0.40	GO:0030315	T-tubule
0.39	GO:0009897	external side of plasma membrane

sp|Q90867|HNF1A_CHICK
Hepatocyte nuclear factor 1-alpha
Search

HNF1A

0.94	Transcription factor 2 splice variant

0.73	GO:0045893	positive regulation of transcription, DNA-templated
0.63	GO:0035623	renal glucose absorption
0.60	GO:0048341	paraxial mesoderm formation
0.60	GO:0030073	insulin secretion
0.59	GO:0006699	bile acid biosynthetic process
0.59	GO:0045453	bone resorption
0.59	GO:0043691	reverse cholesterol transport
0.59	GO:0031018	endocrine pancreas development
0.58	GO:0015721	bile acid and bile salt transport
0.58	GO:0046323	glucose import

0.56	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.55	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.54	GO:0000987	proximal promoter sequence-specific DNA binding
0.53	GO:0042803	protein homodimerization activity
0.53	GO:0046982	protein heterodimerization activity
0.40	GO:0001221	transcription cofactor binding
0.40	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.38	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.33	GO:0032403	protein complex binding

0.61	GO:0005634	nucleus
0.57	GO:0001750	photoreceptor outer segment
0.53	GO:0005667	transcription factor complex
0.39	GO:0005737	cytoplasm
0.37	GO:0070013	intracellular organelle lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q90871|IRF8_CHICK
Interferon regulatory factor 8
Search

IRF8

0.97	Interferon regulatory factor 8

0.58	GO:0044130	negative regulation of growth of symbiont in host
0.58	GO:0042832	defense response to protozoan
0.58	GO:0032735	positive regulation of interleukin-12 production
0.58	GO:0030099	myeloid cell differentiation
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0032729	positive regulation of interferon-gamma production
0.57	GO:0071346	cellular response to interferon-gamma
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression

0.75	GO:0044212	transcription regulatory region DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.52	GO:1990837	sequence-specific double-stranded DNA binding
0.38	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.36	GO:0004725	protein tyrosine phosphatase activity
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.48	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.38

EC:3.1.3

GO:0008138

sp|Q90872|IFNA3_CHICK
Interferon type A3
Search

0.85	Interferon type B

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.58	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.58	GO:0002323	natural killer cell activation involved in immune response
0.57	GO:0042100	B cell proliferation
0.56	GO:0002286	T cell activation involved in immune response
0.56	GO:0043330	response to exogenous dsRNA
0.55	GO:0030183	B cell differentiation
0.54	GO:0002250	adaptive immune response
0.54	GO:0006959	humoral immune response

0.81	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.51	GO:0032403	protein complex binding

0.73

GO:0005615

extracellular space

sp|Q90873|IFNB_CHICK
Interferon type B
Search

0.90	Interferon type B

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.52	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.52	GO:0002323	natural killer cell activation involved in immune response
0.52	GO:0042100	B cell proliferation
0.51	GO:0002286	T cell activation involved in immune response
0.51	GO:0043330	response to exogenous dsRNA
0.51	GO:0030183	B cell differentiation
0.50	GO:0002250	adaptive immune response
0.49	GO:0006959	humoral immune response

0.81	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.47	GO:0032403	protein complex binding

0.73

GO:0005615

extracellular space

sp|Q90875|ACOC_CHICK
Cytoplasmic aconitate hydratase
Search

ACO1

0.86	Cytoplasmic aconitate hydratase

0.86	GO:0010040	response to iron(II) ion
0.76	GO:0006879	cellular iron ion homeostasis
0.52	GO:0050892	intestinal absorption
0.48	GO:0006101	citrate metabolic process
0.48	GO:0009791	post-embryonic development
0.45	GO:0006417	regulation of translation
0.37	GO:0009060	aerobic respiration
0.35	GO:0001889	liver development
0.30	GO:0044238	primary metabolic process

0.79	GO:0003994	aconitate hydratase activity
0.67	GO:0051539	4 iron, 4 sulfur cluster binding
0.58	GO:0030350	iron-responsive element binding
0.52	GO:0051538	3 iron, 4 sulfur cluster binding
0.35	GO:0046872	metal ion binding
0.34	GO:0048027	mRNA 5'-UTR binding
0.33	GO:0005515	protein binding

0.48	GO:0005737	cytoplasm
0.46	GO:0012505	endomembrane system
0.41	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0070062	extracellular exosome

0.79

EC:4.2.1.3

GO:0003994

sp|Q90876|IRF1_CHICK
Interferon regulatory factor 1
Search

IRF1

0.92	Interferon regulatory factor

0.74	GO:0008285	negative regulation of cell proliferation
0.73	GO:0006915	apoptotic process
0.68	GO:0050776	regulation of immune response
0.60	GO:2000564	regulation of CD8-positive, alpha-beta T cell proliferation
0.60	GO:0045590	negative regulation of regulatory T cell differentiation
0.60	GO:0035458	cellular response to interferon-beta
0.59	GO:0045084	positive regulation of interleukin-12 biosynthetic process
0.59	GO:0032728	positive regulation of interferon-beta production
0.59	GO:0043374	CD8-positive, alpha-beta T cell differentiation
0.59	GO:0060333	interferon-gamma-mediated signaling pathway

0.76	GO:0044212	transcription regulatory region DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:1990837	sequence-specific double-stranded DNA binding
0.36	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.51	GO:0000785	chromatin
0.51	GO:0070013	intracellular organelle lumen
0.43	GO:0005925	focal adhesion
0.40	GO:0005737	cytoplasm

sp|Q90879|UB2V1_CHICK
Ubiquitin-conjugating enzyme E2 variant 1
Search

UBE2V1

0.95	Ubiquitin-conjugating enzyme E2 variant 1

0.75	GO:0070534	protein K63-linked ubiquitination
0.72	GO:0006301	postreplication repair
0.58	GO:0000729	DNA double-strand break processing
0.57	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.56	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.42	GO:0006282	regulation of DNA repair
0.41	GO:0051965	positive regulation of synapse assembly
0.41	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.41	GO:2001022	positive regulation of response to DNA damage stimulus
0.41	GO:0043524	negative regulation of neuron apoptotic process

0.64	GO:0004842	ubiquitin-protein transferase activity
0.63	GO:0031625	ubiquitin protein ligase binding
0.62	GO:0061650	ubiquitin-like protein conjugating enzyme activity
0.61	GO:0061659	ubiquitin-like protein ligase activity
0.41	GO:0031624	ubiquitin conjugating enzyme binding

0.73	GO:0031371	ubiquitin conjugating enzyme complex
0.61	GO:0005654	nucleoplasm
0.55	GO:0000151	ubiquitin ligase complex
0.45	GO:0005737	cytoplasm
0.42	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.64

GO:0004842

sp|Q90881|LHX9_CHICK
LIM/homeobox protein Lhx9
Search

LHX9

0.92	LIM homeobox 9

0.59	GO:0035262	gonad morphogenesis
0.57	GO:0008584	male gonad development
0.57	GO:0008585	female gonad development
0.54	GO:0008283	cell proliferation
0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.52	GO:0021794	thalamus development
0.50	GO:0030182	neuron differentiation
0.47	GO:0001708	cell fate specification

0.60	GO:0043565	sequence-specific DNA binding
0.54	GO:0046872	metal ion binding
0.41	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.41	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.41	GO:0001012	RNA polymerase II regulatory region DNA binding
0.40	GO:0003682	chromatin binding
0.39	GO:0003690	double-stranded DNA binding

0.61

GO:0005634

nucleus

sp|Q90888|MAFB_CHICK
Transcription factor MafB
Search

MAFB

0.95	Basic domain leucine zipper transcription factor

0.60	GO:0021572	rhombomere 6 development
0.59	GO:0021598	abducens nerve morphogenesis
0.59	GO:0021571	rhombomere 5 development
0.58	GO:0035283	central nervous system segmentation
0.58	GO:0045647	negative regulation of erythrocyte differentiation
0.58	GO:0021603	cranial nerve formation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0045671	negative regulation of osteoclast differentiation

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.51	GO:0001067	regulatory region nucleic acid binding
0.49	GO:0008134	transcription factor binding
0.38	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.50	GO:0005667	transcription factor complex
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q90889|MAFG_CHICK
Transcription factor MafG
Search

MAFG

0.94	Transcription factor MafG

0.57	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0045604	regulation of epidermal cell differentiation
0.48	GO:0030534	adult behavior
0.46	GO:0001701	in utero embryonic development
0.46	GO:0042127	regulation of cell proliferation
0.45	GO:0051254	positive regulation of RNA metabolic process
0.44	GO:0010557	positive regulation of macromolecule biosynthetic process

0.74	GO:0046982	protein heterodimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.46	GO:0001067	regulatory region nucleic acid binding

0.61	GO:0005634	nucleus
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part

sp|Q90890|LY86_CHICK
Lymphocyte antigen 86
Search

LY86

0.97	Lymphocyte antigen 86

0.86	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway
0.47	GO:0006954	inflammatory response
0.46	GO:0045087	innate immune response

0.44

GO:0005615

extracellular space

sp|Q90891|MP2K2_CHICK
Dual specificity mitogen-activated protein kinase kinase 2
Search

MAP2K2

0.91	Dual specificity mitogen-activated protein kinase kinase 2

0.63	GO:0006468	protein phosphorylation
0.56	GO:0060502	epithelial cell proliferation involved in lung morphogenesis
0.55	GO:0060440	trachea formation
0.54	GO:0030878	thyroid gland development
0.53	GO:0048679	regulation of axon regeneration
0.53	GO:0048538	thymus development
0.53	GO:0060324	face development
0.53	GO:0050772	positive regulation of axonogenesis
0.51	GO:0001932	regulation of protein phosphorylation
0.50	GO:0007507	heart development

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0032947	protein complex scaffold activity
0.47	GO:0004708	MAP kinase kinase activity
0.46	GO:0097110	scaffold protein binding
0.46	GO:0043539	protein serine/threonine kinase activator activity
0.43	GO:0030165	PDZ domain binding

0.42	GO:0005783	endoplasmic reticulum
0.41	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0005911	cell-cell junction
0.41	GO:0009898	cytoplasmic side of plasma membrane
0.40	GO:0005874	microtubule
0.40	GO:0005794	Golgi apparatus
0.38	GO:0005829	cytosol
0.37	GO:0005925	focal adhesion
0.37	GO:0005770	late endosome
0.37	GO:0005769	early endosome

0.69

GO:0004674

sp|Q90922|NET1_CHICK
Netrin-1
Search

0.89	LOW QUALITY PROTEIN: netrin-3

0.56	GO:0071678	olfactory bulb axon guidance
0.56	GO:0030516	regulation of axon extension
0.55	GO:0021960	anterior commissure morphogenesis
0.52	GO:0033564	anterior/posterior axon guidance
0.52	GO:0016358	dendrite development
0.49	GO:0035908	ventral aorta development
0.49	GO:0048562	embryonic organ morphogenesis
0.48	GO:0051093	negative regulation of developmental process
0.48	GO:0061626	pharyngeal arch artery morphogenesis
0.47	GO:0051241	negative regulation of multicellular organismal process

0.37

GO:0005515

protein binding

0.64	GO:0005576	extracellular region
0.35	GO:0005737	cytoplasm
0.33	GO:0012505	endomembrane system
0.33	GO:0071944	cell periphery
0.32	GO:0043227	membrane-bounded organelle
0.32	GO:0043229	intracellular organelle
0.30	GO:0016021	integral component of membrane

sp|Q90923|NET3_CHICK
Netrin-3 (Fragment)
Search

0.87	LOW QUALITY PROTEIN: netrin-3

0.54	GO:0071678	olfactory bulb axon guidance
0.53	GO:0030516	regulation of axon extension
0.53	GO:0021960	anterior commissure morphogenesis
0.50	GO:0033564	anterior/posterior axon guidance
0.50	GO:0016358	dendrite development
0.47	GO:0035908	ventral aorta development
0.47	GO:0048562	embryonic organ morphogenesis
0.46	GO:0061626	pharyngeal arch artery morphogenesis
0.46	GO:0051093	negative regulation of developmental process
0.46	GO:0051241	negative regulation of multicellular organismal process

0.39

GO:0005515

protein binding

0.65	GO:0005576	extracellular region
0.38	GO:0005794	Golgi apparatus
0.33	GO:0071944	cell periphery

sp|Q90932|NFIX_CHICK
Nuclear factor 1 X-type
Search

NFIX

0.77	Nuclear factor 1 X-type

0.66	GO:0006260	DNA replication
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:1902680	positive regulation of RNA biosynthetic process
0.48	GO:1902679	negative regulation of RNA biosynthetic process
0.40	GO:0021684	cerebellar granular layer formation
0.39	GO:0021533	cell differentiation in hindbrain
0.39	GO:0021680	cerebellar Purkinje cell layer development

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.38	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|Q90935|NEUS_CHICK
Neuroserpin
Search

SERPINI1

0.96	Putative neuroserpin is a inhibitory member of the serine proteinase inhibitor

0.55	GO:0010951	negative regulation of endopeptidase activity
0.43	GO:2000266	regulation of blood coagulation, intrinsic pathway
0.39	GO:0010976	positive regulation of neuron projection development
0.38	GO:0030155	regulation of cell adhesion
0.36	GO:0071391	cellular response to estrogen stimulus
0.35	GO:0007422	peripheral nervous system development
0.34	GO:0007417	central nervous system development
0.33	GO:0015986	ATP synthesis coupled proton transport
0.33	GO:0050829	defense response to Gram-negative bacterium
0.33	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

0.57	GO:0004867	serine-type endopeptidase inhibitor activity
0.41	GO:0008201	heparin binding
0.33	GO:0002020	protease binding
0.33	GO:0015078	hydrogen ion transmembrane transporter activity
0.32	GO:0042802	identical protein binding
0.32	GO:0005509	calcium ion binding

0.73	GO:0005615	extracellular space
0.59	GO:0060205	cytoplasmic vesicle lumen
0.56	GO:0043025	neuronal cell body
0.55	GO:0030141	secretory granule
0.36	GO:1903561	extracellular vesicle
0.33	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q90941|PB1_CHICK
Protein polybromo-1
Search

PBRM1

0.91	Polybromo 1

0.78	GO:0006338	chromatin remodeling
0.63	GO:0008285	negative regulation of cell proliferation
0.38	GO:0001890	placenta development
0.37	GO:0007507	heart development

0.77	GO:0003682	chromatin binding
0.55	GO:0003677	DNA binding

0.83	GO:0016586	RSC-type complex
0.57	GO:0005654	nucleoplasm
0.37	GO:0000776	kinetochore
0.30	GO:0031224	intrinsic component of membrane

sp|Q90944|EPYC_CHICK
Epiphycan
Search

EPYC

0.97	Dermatan sulfate proteoglycan 3

0.72	GO:0007409	axonogenesis
0.44	GO:0016525	negative regulation of angiogenesis
0.42	GO:0007565	female pregnancy

0.40	GO:0005515	protein binding
0.40	GO:0005539	glycosaminoglycan binding
0.38	GO:0044877	macromolecular complex binding
0.37	GO:0005201	extracellular matrix structural constituent

0.73	GO:0005578	proteinaceous extracellular matrix
0.67	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

sp|Q90952|PON2_CHICK
Serum paraoxonase/arylesterase 2
Search

PON2

0.96	Serum paraoxonase/arylesterase 2

0.44	GO:0009636	response to toxic substance
0.44	GO:0019439	aromatic compound catabolic process
0.44	GO:0010875	positive regulation of cholesterol efflux
0.43	GO:0016311	dephosphorylation
0.42	GO:0032411	positive regulation of transporter activity
0.42	GO:0051099	positive regulation of binding
0.42	GO:0008203	cholesterol metabolic process
0.42	GO:0046470	phosphatidylcholine metabolic process
0.42	GO:1902617	response to fluoride
0.41	GO:0019372	lipoxygenase pathway

0.85	GO:0004064	arylesterase activity
0.51	GO:0004063	aryldialkylphosphatase activity
0.50	GO:0102007	acyl-L-homoserine-lactone lactonohydrolase activity
0.46	GO:0042802	identical protein binding
0.40	GO:0005543	phospholipid binding
0.40	GO:0046983	protein dimerization activity
0.40	GO:0005509	calcium ion binding
0.37	GO:0018733	3,4-dihydrocoumarin hydrolase activity
0.37	GO:0047856	dihydrocoumarin hydrolase activity
0.37	GO:0008035	high-density lipoprotein particle binding

0.62	GO:0005576	extracellular region
0.44	GO:1990777	lipoprotein particle
0.39	GO:0005764	lysosome
0.38	GO:0031982	vesicle
0.37	GO:0005886	plasma membrane
0.36	GO:0005634	nucleus
0.36	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.85	EC:3.1.1.2	GO:0004064
0.37	KEGG:R03692	GO:0047856

sp|Q90953|CSPG2_CHICK
Versican core protein
Search

0.10	Versican core protein

0.57	GO:0007155	cell adhesion
0.43	GO:0035775	pronephric glomerulus morphogenesis
0.42	GO:0003093	regulation of glomerular filtration
0.42	GO:0036072	direct ossification
0.42	GO:0003203	endocardial cushion morphogenesis
0.40	GO:0001501	skeletal system development
0.40	GO:0007417	central nervous system development

0.68	GO:0005509	calcium ion binding
0.66	GO:0005540	hyaluronic acid binding
0.41	GO:0005201	extracellular matrix structural constituent
0.30	GO:0030246	carbohydrate binding

0.42	GO:0031012	extracellular matrix
0.38	GO:0005615	extracellular space

sp|Q90955|TEBP_CHICK
Prostaglandin E synthase 3 (Fragment)
Search

PTGES3

0.97	Prostaglandin E synthase 3

0.73	GO:0046457	prostanoid biosynthetic process
0.72	GO:0006693	prostaglandin metabolic process
0.72	GO:1905323	telomerase holoenzyme complex assembly
0.69	GO:0051973	positive regulation of telomerase activity
0.68	GO:0007004	telomere maintenance via telomerase
0.68	GO:0060430	lung saccule development
0.67	GO:0042921	glucocorticoid receptor signaling pathway
0.63	GO:0043588	skin development
0.61	GO:0008283	cell proliferation
0.59	GO:0005978	glycogen biosynthetic process

0.69	GO:0070182	DNA polymerase binding
0.62	GO:0050220	prostaglandin-E synthase activity
0.50	GO:0003720	telomerase activity
0.48	GO:0051879	Hsp90 protein binding
0.44	GO:0051082	unfolded protein binding
0.44	GO:0002039	p53 binding
0.42	GO:0033142	progesterone receptor binding
0.40	GO:0003896	DNA primase activity
0.35	GO:0046872	metal ion binding
0.33	GO:0030554	adenyl nucleotide binding

0.59	GO:0005654	nucleoplasm
0.59	GO:0005829	cytosol
0.50	GO:0005697	telomerase holoenzyme complex
0.43	GO:0005884	actin filament
0.43	GO:0070062	extracellular exosome
0.43	GO:0043025	neuronal cell body
0.42	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0043005	neuron projection
0.40	GO:0043234	protein complex
0.39	GO:0000781	chromosome, telomeric region

0.62	EC:5.3.99.3	GO:0050220
0.62	KEGG:R02265	GO:0050220

sp|Q90963|PRRX2_CHICK
Paired mesoderm homeobox protein 2 (Fragment)
Search

PRRX2

0.97	Paired mesoderm homeobox protein 2

0.69	GO:0007275	multicellular organism development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0002053	positive regulation of mesenchymal cell proliferation
0.52	GO:0045880	positive regulation of smoothened signaling pathway
0.52	GO:1904888	cranial skeletal system development
0.51	GO:0097150	neuronal stem cell population maintenance
0.50	GO:0061448	connective tissue development
0.50	GO:0060021	palate development

0.64	GO:0043565	sequence-specific DNA binding
0.53	GO:0071837	HMG box domain binding
0.51	GO:0001105	RNA polymerase II transcription coactivator activity
0.50	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003690	double-stranded DNA binding
0.37	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.44	GO:0005829	cytosol
0.43	GO:0043233	organelle lumen
0.40	GO:0044446	intracellular organelle part

sp|Q90964|FOXG1_CHICK
Forkhead box protein G1
Search

FOXG1

0.89	Transforming protein Qin

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0043584	nose development
0.48	GO:0060059	embryonic retina morphogenesis in camera-type eye
0.47	GO:0030154	cell differentiation
0.46	GO:1902679	negative regulation of RNA biosynthetic process
0.45	GO:0007399	nervous system development
0.39	GO:0006351	transcription, DNA-templated
0.38	GO:0051961	negative regulation of nervous system development

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003779	actin binding

0.61	GO:0005634	nucleus
0.36	GO:0042025	host cell nucleus
0.30	GO:0016021	integral component of membrane

sp|Q90965|RAB2A_CHICK
Ras-related protein Rab-2A
Search

RAB2A

0.94	RAS oncogene family member RAB2

0.62

GO:0007030

Golgi organization

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.58

GO:0005794

Golgi apparatus

sp|Q90966|RARA_CHICK
Retinoic acid receptor alpha
Search

RARA

0.93	Retinoic acid receptor alpha

0.85	GO:0048384	retinoic acid receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:0060010	Sertoli cell fate commitment
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0003417	growth plate cartilage development
0.55	GO:0045630	positive regulation of T-helper 2 cell differentiation
0.55	GO:0055012	ventricular cardiac muscle cell differentiation

0.85	GO:0003708	retinoic acid receptor activity
0.79	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.54	GO:0043422	protein kinase B binding
0.54	GO:0001972	retinoic acid binding
0.53	GO:0051393	alpha-actinin binding
0.52	GO:0051018	protein kinase A binding
0.51	GO:0031490	chromatin DNA binding
0.50	GO:0003714	transcription corepressor activity

0.61	GO:0005634	nucleus
0.50	GO:0043025	neuronal cell body
0.50	GO:0030425	dendrite
0.47	GO:0015629	actin cytoskeleton
0.47	GO:0000785	chromatin
0.46	GO:0070013	intracellular organelle lumen
0.45	GO:0005829	cytosol
0.40	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0009986	cell surface
0.30	GO:0016020	membrane

sp|Q90972|RNF13_CHICK
E3 ubiquitin-protein ligase RNF13
Search

RNF13

0.91	Ring finger protein 13

0.64

GO:0051865

protein autoubiquitination

0.59	GO:0061630	ubiquitin protein ligase activity
0.47	GO:0008270	zinc ion binding

0.63	GO:0031902	late endosome membrane
0.62	GO:0005765	lysosomal membrane
0.58	GO:0005654	nucleoplasm
0.57	GO:0005829	cytosol
0.30	GO:0044425	membrane part

sp|Q90977|E2F1_CHICK
Transcription factor E2F1
Search

E2F1

0.96	E2F transcription factor 1

0.74	GO:1990086	lens fiber cell apoptotic process
0.70	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.67	GO:0070345	negative regulation of fat cell proliferation
0.66	GO:0043276	anoikis
0.65	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle
0.64	GO:0051093	negative regulation of developmental process
0.62	GO:0048255	mRNA stabilization
0.62	GO:0048146	positive regulation of fibroblast proliferation
0.62	GO:0045944	positive regulation of transcription by RNA polymerase II
0.62	GO:0043392	negative regulation of DNA binding

0.68	GO:0046983	protein dimerization activity
0.67	GO:0001047	core promoter binding
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0008134	transcription factor binding
0.55	GO:0043565	sequence-specific DNA binding
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.36	GO:0019901	protein kinase binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.57	GO:0005813	centrosome
0.54	GO:0000785	chromatin
0.52	GO:0031974	membrane-enclosed lumen
0.41	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q90979|Q90979_CHICK
Transcription factor
Search

NRF1

0.97	LOW QUALITY PROTEIN: nuclear respiratory factor 1

0.55	GO:0006366	transcription by RNA polymerase II
0.55	GO:0045944	positive regulation of transcription by RNA polymerase II
0.50	GO:0014823	response to activity
0.49	GO:0045494	photoreceptor cell maintenance
0.49	GO:0003407	neural retina development
0.48	GO:0070417	cellular response to cold
0.38	GO:0007005	mitochondrion organization
0.34	GO:0006091	generation of precursor metabolites and energy

0.80	GO:0001046	core promoter sequence-specific DNA binding
0.72	GO:0042803	protein homodimerization activity
0.58	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.60	GO:0005634	nucleus
0.52	GO:0005829	cytosol
0.51	GO:0031974	membrane-enclosed lumen
0.46	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.35	GO:0005667	transcription factor complex

sp|Q90980|CNG3_CHICK
Cyclic nucleotide-gated channel rod photoreceptor subunit alpha
Search

CNGA1

0.96	Cyclic nucleotide-gated channel rod photoreceptor subunit alpha

0.74	GO:0007601	visual perception
0.60	GO:0034220	ion transmembrane transport
0.59	GO:0006812	cation transport
0.45	GO:0042391	regulation of membrane potential
0.35	GO:0050896	response to stimulus
0.35	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.34	GO:0051480	regulation of cytosolic calcium ion concentration
0.34	GO:0007283	spermatogenesis
0.33	GO:0023052	signaling
0.33	GO:0007154	cell communication

0.83	GO:0005221	intracellular cyclic nucleotide activated cation channel activity
0.49	GO:0005249	voltage-gated potassium channel activity
0.42	GO:0030553	cGMP binding
0.35	GO:0030552	cAMP binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity

0.51	GO:0042622	photoreceptor outer segment membrane
0.41	GO:0005887	integral component of plasma membrane
0.36	GO:1902495	transmembrane transporter complex
0.35	GO:0043195	terminal bouton
0.33	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm

sp|Q90986|LY6E_CHICK
Lymphocyte antigen 6E
Search

LY6E

0.91	Lymphocyte antigen 6E

0.41	GO:0002320	lymphoid progenitor cell differentiation
0.39	GO:0008283	cell proliferation

0.42	GO:0009986	cell surface
0.39	GO:0031225	anchored component of membrane
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q90987|STMN2_CHICK
Stathmin-2
Search

STMN2

0.85

Stathmin

0.84	GO:0031110	regulation of microtubule polymerization or depolymerization
0.55	GO:0048699	generation of neurons
0.54	GO:1990090	cellular response to nerve growth factor stimulus
0.54	GO:0032272	negative regulation of protein polymerization
0.53	GO:1902904	negative regulation of supramolecular fiber organization
0.53	GO:0051494	negative regulation of cytoskeleton organization
0.52	GO:1901881	positive regulation of protein depolymerization
0.52	GO:0007019	microtubule depolymerization
0.51	GO:0031346	positive regulation of cell projection organization
0.51	GO:0031345	negative regulation of cell projection organization

0.53	GO:0048306	calcium-dependent protein binding
0.49	GO:0015631	tubulin binding
0.35	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity
0.32	GO:0004871	signal transducer activity

0.53	GO:0043005	neuron projection
0.52	GO:0030027	lamellipodium
0.51	GO:0030427	site of polarized growth
0.51	GO:0043025	neuronal cell body
0.50	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0120038	plasma membrane bounded cell projection part
0.38	GO:0005829	cytosol
0.37	GO:0031982	vesicle
0.37	GO:0005794	Golgi apparatus
0.34	GO:0005874	microtubule

0.35

EC:3.1.1.47

GO:0003847

sp|Q90988|SMC2_CHICK
Structural maintenance of chromosomes protein 2
Search

sp|Q90997|TFR1_CHICK
Transferrin receptor protein 1
Search

TFRC

0.95	Transferrin receptor

0.85	GO:0033572	transferrin transport
0.73	GO:0006879	cellular iron ion homeostasis
0.68	GO:0006898	receptor-mediated endocytosis
0.57	GO:0045830	positive regulation of isotype switching
0.57	GO:0030890	positive regulation of B cell proliferation
0.56	GO:0097286	iron ion import
0.56	GO:0042102	positive regulation of T cell proliferation
0.55	GO:0045780	positive regulation of bone resorption
0.54	GO:0030316	osteoclast differentiation
0.53	GO:0043112	receptor metabolic process

0.85	GO:0033570	transferrin transmembrane transporter activity
0.85	GO:0004998	transferrin receptor activity
0.50	GO:0003725	double-stranded RNA binding
0.49	GO:0042803	protein homodimerization activity
0.37	GO:0039706	co-receptor binding
0.35	GO:0001618	virus receptor activity
0.34	GO:0030544	Hsp70 protein binding
0.34	GO:0051087	chaperone binding

0.56	GO:1990712	HFE-transferrin receptor complex
0.53	GO:0055037	recycling endosome
0.53	GO:0009897	external side of plasma membrane
0.52	GO:0016323	basolateral plasma membrane
0.52	GO:0005905	clathrin-coated pit
0.51	GO:0070062	extracellular exosome
0.51	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005769	early endosome
0.51	GO:0010008	endosome membrane
0.46	GO:0005887	integral component of plasma membrane

tr|Q90998|Q90998_CHICK
Transforming growth factor-beta type III receptor
Search

TGFBR3

0.96	Transforming growth factor beta receptor type 3

0.61	GO:0034699	response to luteinizing hormone
0.60	GO:0060317	cardiac epithelial to mesenchymal transition
0.59	GO:0032354	response to follicle-stimulating hormone
0.58	GO:0060389	pathway-restricted SMAD protein phosphorylation
0.58	GO:0034695	response to prostaglandin E
0.56	GO:0030509	BMP signaling pathway
0.55	GO:0007179	transforming growth factor beta receptor signaling pathway
0.55	GO:0051271	negative regulation of cellular component movement
0.51	GO:0006955	immune response
0.47	GO:0009790	embryo development

0.64	GO:0070123	transforming growth factor beta receptor activity, type III
0.61	GO:0050431	transforming growth factor beta binding
0.59	GO:0005114	type II transforming growth factor beta receptor binding
0.57	GO:0015026	coreceptor activity
0.56	GO:0046332	SMAD binding
0.45	GO:0005539	glycosaminoglycan binding
0.41	GO:0048185	activin binding
0.40	GO:0017134	fibroblast growth factor binding
0.38	GO:0030165	PDZ domain binding
0.38	GO:1901681	sulfur compound binding

0.63	GO:0005576	extracellular region
0.60	GO:0034673	inhibin-betaglycan-ActRII complex
0.55	GO:0009897	external side of plasma membrane
0.53	GO:0043235	receptor complex
0.41	GO:0005887	integral component of plasma membrane
0.37	GO:0005622	intracellular
0.35	GO:0031982	vesicle
0.35	GO:0012505	endomembrane system

sp|Q90999|TGFR2_CHICK
TGF-beta receptor type-2
Search

TGFBR2

0.74	Serine/threonine-protein kinase receptor

0.80	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.74	GO:0071560	cellular response to transforming growth factor beta stimulus
0.66	GO:0023014	signal transduction by protein phosphorylation
0.64	GO:0006915	apoptotic process
0.63	GO:0040008	regulation of growth
0.61	GO:0030154	cell differentiation
0.60	GO:1905317	inferior endocardial cushion morphogenesis
0.60	GO:0002651	positive regulation of tolerance induction to self antigen
0.59	GO:0060434	bronchus morphogenesis
0.59	GO:0002661	regulation of B cell tolerance induction

0.86	GO:0005026	transforming growth factor beta receptor activity, type II
0.79	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.58	GO:0034713	type I transforming growth factor beta receptor binding
0.58	GO:0050431	transforming growth factor beta binding
0.55	GO:0030554	adenyl nucleotide binding
0.55	GO:0046332	SMAD binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0046872	metal ion binding

0.70	GO:0043235	receptor complex
0.54	GO:0005901	caveola
0.53	GO:0009897	external side of plasma membrane
0.37	GO:0005829	cytosol
0.36	GO:0005887	integral component of plasma membrane
0.36	GO:1902554	serine/threonine protein kinase complex
0.34	GO:0031012	extracellular matrix

0.79

GO:0004702

tr|Q90VW0|Q90VW0_CHICK
TOB protein
Search

TOB1

0.92	Putative anti-proliferation factor btg1/tob

0.79	GO:0008285	negative regulation of cell proliferation
0.58	GO:0060212	negative regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.57	GO:0007184	SMAD protein import into nucleus
0.56	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.54	GO:0045668	negative regulation of osteoblast differentiation
0.54	GO:0030514	negative regulation of BMP signaling pathway
0.50	GO:0017148	negative regulation of translation
0.49	GO:1903507	negative regulation of nucleic acid-templated transcription
0.48	GO:0030509	BMP signaling pathway
0.41	GO:0060070	canonical Wnt signaling pathway

0.54	GO:0030971	receptor tyrosine kinase binding
0.53	GO:0003714	transcription corepressor activity
0.53	GO:0046332	SMAD binding
0.34	GO:0042809	vitamin D receptor binding
0.34	GO:0005070	SH3/SH2 adaptor activity

0.53	GO:0030014	CCR4-NOT complex
0.41	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm

sp|Q90VZ9|HXA7_CHICK
Homeobox protein Hox-A7
Search

HOXA7

0.96	Homeobox protein Hox-A7 (Predicted)

0.67	GO:0007275	multicellular organism development
0.62	GO:0045617	negative regulation of keratinocyte differentiation
0.62	GO:0045656	negative regulation of monocyte differentiation
0.60	GO:0002686	negative regulation of leukocyte migration
0.60	GO:0001953	negative regulation of cell-matrix adhesion
0.57	GO:0048863	stem cell differentiation
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0006366	transcription by RNA polymerase II

0.63	GO:0043565	sequence-specific DNA binding
0.59	GO:0003700	DNA binding transcription factor activity
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0008134	transcription factor binding
0.52	GO:0003690	double-stranded DNA binding
0.34	GO:0042803	protein homodimerization activity

0.61	GO:0005634	nucleus
0.49	GO:0012505	endomembrane system
0.49	GO:0031974	membrane-enclosed lumen
0.46	GO:0031967	organelle envelope
0.46	GO:0031090	organelle membrane

sp|Q90W79|CNTN5_CHICK
Contactin-5
Search

CNTN5

0.85	Contactin 5

0.69	GO:0007605	sensory perception of sound
0.51	GO:0007155	cell adhesion
0.48	GO:0030182	neuron differentiation
0.45	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.44	GO:0000904	cell morphogenesis involved in differentiation
0.44	GO:0120036	plasma membrane bounded cell projection organization
0.42	GO:0006935	chemotaxis
0.42	GO:0006928	movement of cell or subcellular component
0.41	GO:0006501	C-terminal protein lipidation
0.38	GO:0045665	negative regulation of neuron differentiation

0.44

GO:0005112

Notch binding

0.64	GO:0005829	cytosol
0.45	GO:0031225	anchored component of membrane
0.38	GO:0005886	plasma membrane
0.37	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

tr|Q90W83|Q90W83_CHICK
Aldo-keto reductase
Search

0.40	Aldo-keto reductase

0.53	GO:0055114	oxidation-reduction process
0.40	GO:0016488	farnesol catabolic process
0.39	GO:0044598	doxorubicin metabolic process
0.39	GO:0044597	daunorubicin metabolic process
0.37	GO:0001523	retinoid metabolic process
0.35	GO:0008202	steroid metabolic process
0.35	GO:0006081	cellular aldehyde metabolic process
0.34	GO:0007586	digestion
0.34	GO:0034754	cellular hormone metabolic process
0.34	GO:0042446	hormone biosynthetic process

0.54	GO:0016491	oxidoreductase activity
0.35	GO:0005536	glucose binding
0.35	GO:0070401	NADP+ binding
0.35	GO:0070402	NADPH binding
0.33	GO:0005515	protein binding

0.35	GO:0005739	mitochondrion
0.34	GO:0005829	cytosol
0.34	GO:0070062	extracellular exosome
0.34	GO:0005764	lysosome
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part

0.54

GO:0016491

tr|Q90WA9|Q90WA9_CHICK
Fatty acid-binding protein, liver
Search

FABP1

0.85	Fatty acid-binding protein, liver

0.56	GO:0070301	cellular response to hydrogen peroxide
0.55	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.55	GO:0071456	cellular response to hypoxia
0.48	GO:0098869	cellular oxidant detoxification
0.41	GO:0032000	positive regulation of fatty acid beta-oxidation
0.40	GO:0050892	intestinal absorption
0.39	GO:0015909	long-chain fatty acid transport
0.38	GO:0051345	positive regulation of hydrolase activity
0.36	GO:0019082	viral protein processing
0.35	GO:0019433	triglyceride catabolic process

0.72	GO:0033293	monocarboxylic acid binding
0.71	GO:0008289	lipid binding
0.51	GO:0003682	chromatin binding
0.48	GO:0016209	antioxidant activity
0.40	GO:0005324	long-chain fatty acid transporter activity
0.35	GO:0051978	lysophospholipid transporter activity
0.34	GO:0008144	drug binding
0.34	GO:0005515	protein binding

0.49	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol
0.40	GO:0045179	apical cortex
0.40	GO:0031907	microbody lumen
0.38	GO:0044439	peroxisomal part
0.36	GO:0070062	extracellular exosome
0.35	GO:0043234	protein complex

sp|Q90WD0|ARP3_CHICK
Actin-related protein 3
Search

ACTR3

0.85	Actin-related protein 3

0.81	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.55	GO:0016344	meiotic chromosome movement towards spindle pole
0.53	GO:0033206	meiotic cytokinesis
0.52	GO:0071346	cellular response to interferon-gamma
0.52	GO:0008356	asymmetric cell division
0.51	GO:0051653	spindle localization
0.50	GO:0060271	cilium assembly
0.49	GO:0007163	establishment or maintenance of cell polarity
0.36	GO:1905836	response to triterpenoid
0.36	GO:1905834	response to pyrimidine ribonucleotide

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0051015	actin filament binding
0.48	GO:0005200	structural constituent of cytoskeleton
0.35	GO:0051117	ATPase binding

0.80	GO:0005885	Arp2/3 protein complex
0.51	GO:0030027	lamellipodium
0.51	GO:0005903	brush border
0.48	GO:0005911	cell-cell junction
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.36	GO:0061830	concave side of sperm head
0.36	GO:0061828	apical tubulobulbar complex
0.35	GO:0061825	podosome core
0.35	GO:0030056	hemidesmosome

tr|Q90WF6|Q90WF6_CHICK
ChB1
Search

0.59	C-type lectin short form

0.52

GO:0030246

carbohydrate binding

0.30

GO:0044425

membrane part

sp|Q90WG1|SPINZ_CHICK
Spindlin-Z
Search

SPIN1

0.97	Z-linked spindlin 1

0.78	GO:0007276	gamete generation
0.49	GO:0009303	rRNA transcription
0.48	GO:0030177	positive regulation of Wnt signaling pathway
0.44	GO:0045893	positive regulation of transcription, DNA-templated
0.38	GO:0051321	meiotic cell cycle
0.37	GO:0016055	Wnt signaling pathway
0.37	GO:0016569	covalent chromatin modification
0.36	GO:0007275	multicellular organism development
0.34	GO:0046294	formaldehyde catabolic process
0.34	GO:0022412	cellular process involved in reproduction in multicellular organism

0.49	GO:0140034	methylation-dependent protein binding
0.47	GO:0042393	histone binding
0.34	GO:0018738	S-formylglutathione hydrolase activity
0.34	GO:0003677	DNA binding
0.33	GO:0052689	carboxylic ester hydrolase activity

0.47	GO:0031965	nuclear membrane
0.45	GO:0005819	spindle
0.44	GO:0005730	nucleolus
0.43	GO:0005654	nucleoplasm
0.43	GO:0005829	cytosol

0.34	EC:3.1.2.12	GO:0018738
0.34	KEGG:R00527	GO:0018738

sp|Q90WG2|SPINW_CHICK
Spindlin-W
Search

SPIN1

0.97	W-linked spindlin 1

0.78	GO:0007276	gamete generation
0.49	GO:0009303	rRNA transcription
0.48	GO:0030177	positive regulation of Wnt signaling pathway
0.44	GO:0045893	positive regulation of transcription, DNA-templated
0.38	GO:0051321	meiotic cell cycle
0.37	GO:0016055	Wnt signaling pathway
0.37	GO:0016569	covalent chromatin modification
0.36	GO:0007275	multicellular organism development
0.34	GO:0046294	formaldehyde catabolic process
0.34	GO:0022412	cellular process involved in reproduction in multicellular organism

0.49	GO:0140034	methylation-dependent protein binding
0.47	GO:0042393	histone binding
0.34	GO:0018738	S-formylglutathione hydrolase activity
0.34	GO:0003677	DNA binding
0.33	GO:0052689	carboxylic ester hydrolase activity

0.47	GO:0031965	nuclear membrane
0.45	GO:0005819	spindle
0.44	GO:0005730	nucleolus
0.43	GO:0005654	nucleoplasm
0.43	GO:0005829	cytosol

0.34	EC:3.1.2.12	GO:0018738
0.34	KEGG:R00527	GO:0018738

sp|Q90WI4|MXRA8_CHICK
Matrix remodeling-associated protein 8
Search

0.96	matrix-remodeling-associated protein 8

0.46	GO:0060857	establishment of glial blood-brain barrier
0.34	GO:0016055	Wnt signaling pathway
0.33	GO:0035556	intracellular signal transduction

0.42	GO:0009986	cell surface
0.32	GO:0005622	intracellular
0.30	GO:0044425	membrane part

tr|Q90WK2|Q90WK2_CHICK
Platelet-derived growth factor A chain long form
Search

PDGFA

0.97	Platelet-derived growth factor alpha polypeptide

0.74	GO:0010469	regulation of receptor activity
0.58	GO:1900238	regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
0.58	GO:2000591	positive regulation of metanephric mesenchymal cell migration
0.58	GO:0031954	positive regulation of protein autophosphorylation
0.57	GO:0010512	negative regulation of phosphatidylinositol biosynthetic process
0.56	GO:0010544	negative regulation of platelet activation
0.56	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.55	GO:0014910	regulation of smooth muscle cell migration
0.55	GO:0050919	negative chemotaxis
0.55	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.77	GO:0008083	growth factor activity
0.58	GO:0005161	platelet-derived growth factor receptor binding
0.56	GO:0048407	platelet-derived growth factor binding
0.53	GO:0005518	collagen binding
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0046982	protein heterodimerization activity
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.50	GO:0005615	extracellular space
0.50	GO:0009986	cell surface
0.38	GO:0005902	microvillus
0.36	GO:0031093	platelet alpha granule lumen
0.35	GO:0005796	Golgi lumen
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0000139	Golgi membrane

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

tr|Q90WR6|Q90WR6_CHICK
Sulfotransferase
Search

0.57	Sulfotransferase

0.48	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.48	GO:0006068	ethanol catabolic process
0.48	GO:0051923	sulfation
0.38	GO:0006584	catecholamine metabolic process
0.36	GO:0000103	sulfate assimilation
0.36	GO:0008202	steroid metabolic process
0.35	GO:0006805	xenobiotic metabolic process
0.35	GO:0009812	flavonoid metabolic process
0.35	GO:0098989	NMDA selective glutamate receptor signaling pathway
0.34	GO:0036498	IRE1-mediated unfolded protein response

0.78	GO:0008146	sulfotransferase activity
0.34	GO:0043199	sulfate binding
0.33	GO:0005515	protein binding

0.41	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.78

GO:0008146

sp|Q90WR8|SP3_CHICK
Transcription factor Sp3
Search

SP3

0.96	Transcription factor Sp3

0.58	GO:0043353	enucleate erythrocyte differentiation
0.58	GO:0001779	natural killer cell differentiation
0.57	GO:1903131	mononuclear cell differentiation
0.57	GO:0030219	megakaryocyte differentiation
0.57	GO:0030851	granulocyte differentiation
0.57	GO:0060216	definitive hemopoiesis
0.56	GO:0048596	embryonic camera-type eye morphogenesis
0.55	GO:0030183	B cell differentiation
0.55	GO:0001889	liver development
0.55	GO:0060136	embryonic process involved in female pregnancy

0.75	GO:0000987	proximal promoter sequence-specific DNA binding
0.59	GO:0003700	DNA binding transcription factor activity
0.53	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.51	GO:0003682	chromatin binding
0.35	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding

0.59	GO:0005634	nucleus
0.53	GO:0017053	transcriptional repressor complex
0.37	GO:0032993	protein-DNA complex
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|Q90WR9|Q90WR9_CHICK
Transcription factor
Search

SP1

0.96	Sp1 transcription factor

0.69	GO:0006357	regulation of transcription by RNA polymerase II
0.64	GO:1904828	positive regulation of hydrogen sulfide biosynthetic process
0.62	GO:1905564	positive regulation of vascular endothelial cell proliferation
0.61	GO:0043923	positive regulation by host of viral transcription
0.59	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.58	GO:0045766	positive regulation of angiogenesis
0.54	GO:0006366	transcription by RNA polymerase II
0.52	GO:0045893	positive regulation of transcription, DNA-templated
0.40	GO:0060136	embryonic process involved in female pregnancy
0.40	GO:0048511	rhythmic process

0.61	GO:0071837	HMG box domain binding
0.60	GO:0003700	DNA binding transcription factor activity
0.59	GO:0070491	repressing transcription factor binding
0.58	GO:0042826	histone deacetylase binding
0.57	GO:0008022	protein C-terminus binding
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0042803	protein homodimerization activity
0.41	GO:0043425	bHLH transcription factor binding
0.40	GO:0001046	core promoter sequence-specific DNA binding
0.40	GO:0001085	RNA polymerase II transcription factor binding

0.60	GO:0005634	nucleus
0.56	GO:0017053	transcriptional repressor complex
0.52	GO:0000785	chromatin
0.49	GO:0031974	membrane-enclosed lumen
0.37	GO:0032993	protein-DNA complex
0.34	GO:0005737	cytoplasm

tr|Q90WT9|Q90WT9_CHICK
TNF-related apoptosis inducing ligand-like protein
Search

0.91	Tumor necrosis factor ligand superfamily member 10

0.74	GO:0006955	immune response
0.47	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway
0.43	GO:0010469	regulation of receptor activity
0.42	GO:0090200	positive regulation of release of cytochrome c from mitochondria
0.41	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.41	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.38	GO:0008584	male gonad development
0.37	GO:0032868	response to insulin
0.34	GO:0006915	apoptotic process
0.33	GO:0048305	immunoglobulin secretion

0.83	GO:0005164	tumor necrosis factor receptor binding
0.50	GO:0046872	metal ion binding
0.44	GO:0005125	cytokine activity
0.39	GO:0042802	identical protein binding
0.33	GO:0005174	CD40 receptor binding

0.42	GO:0005615	extracellular space
0.35	GO:1903561	extracellular vesicle
0.33	GO:0009897	external side of plasma membrane
0.31	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q90WU3|DDX1_CHICK
ATP-dependent RNA helicase DDX1
Search

DDX1

0.68	DEAD-box helicase 1

0.60	GO:1903608	protein localization to cytoplasmic stress granule
0.57	GO:0043330	response to exogenous dsRNA
0.56	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.53	GO:0006302	double-strand break repair
0.52	GO:0009615	response to virus
0.51	GO:0032392	DNA geometric change
0.49	GO:0007275	multicellular organism development
0.47	GO:0010501	RNA secondary structure unwinding
0.47	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.44	GO:1903506	regulation of nucleic acid-templated transcription

0.63	GO:0004386	helicase activity
0.58	GO:0008143	poly(A) binding
0.54	GO:0003682	chromatin binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0003712	transcription cofactor activity
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0003725	double-stranded RNA binding
0.47	GO:0042623	ATPase activity, coupled
0.47	GO:0004518	nuclease activity

0.62	GO:0071920	cleavage body
0.59	GO:0072669	tRNA-splicing ligase complex
0.55	GO:0010494	cytoplasmic stress granule
0.49	GO:0005829	cytosol
0.44	GO:0005730	nucleolus
0.30	GO:0016020	membrane

0.47

EC:3.1

GO:0004518

sp|Q90X07|PSN2_CHICK
Presenilin-2
Search

PSEN2

0.79	Presenilin

0.81	GO:0007219	Notch signaling pathway
0.79	GO:0042987	amyloid precursor protein catabolic process
0.75	GO:0016485	protein processing
0.57	GO:0006509	membrane protein ectodomain proteolysis
0.55	GO:0035556	intracellular signal transduction
0.52	GO:0050435	amyloid-beta metabolic process
0.48	GO:0043085	positive regulation of catalytic activity
0.48	GO:0007220	Notch receptor processing
0.45	GO:0043066	negative regulation of apoptotic process
0.44	GO:0061053	somite development

0.75	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving
0.34	GO:0005515	protein binding
0.33	GO:0008324	cation transmembrane transporter activity

0.73	GO:0000139	Golgi membrane
0.71	GO:0005789	endoplasmic reticulum membrane
0.53	GO:0005637	nuclear inner membrane
0.51	GO:0000776	kinetochore
0.51	GO:0005813	centrosome
0.48	GO:0035253	ciliary rootlet
0.48	GO:0043198	dendritic shaft
0.47	GO:0005887	integral component of plasma membrane
0.47	GO:0031594	neuromuscular junction
0.47	GO:0030426	growth cone

0.75

EC:3.4.23

GO:0042500

tr|Q90X14|Q90X14_CHICK
Helix-loop-helix protein
Search

ID3

0.95	Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.55	GO:0045668	negative regulation of osteoblast differentiation
0.55	GO:0043433	negative regulation of DNA binding transcription factor activity
0.54	GO:0007399	nervous system development
0.54	GO:0001656	metanephros development
0.54	GO:0048511	rhythmic process
0.53	GO:0030154	cell differentiation
0.52	GO:0048568	embryonic organ development
0.52	GO:0007507	heart development
0.51	GO:0009888	tissue development

0.68	GO:0046983	protein dimerization activity
0.50	GO:1901707	leptomycin B binding
0.48	GO:0044325	ion channel binding
0.47	GO:0003677	DNA binding
0.45	GO:0008134	transcription factor binding
0.44	GO:0019904	protein domain specific binding
0.40	GO:0003700	DNA binding transcription factor activity
0.35	GO:0008113	peptide-methionine (S)-S-oxide reductase activity

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.40	GO:0043234	protein complex
0.33	GO:0000785	chromatin

0.35

EC:1.8.4 EC:1.8.4.11

GO:0008113

tr|Q90X15|Q90X15_CHICK
Helix-loop-helix protein
Search

ID1

0.79	DNA-binding protein inhibitor ID-1

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.58	GO:0090074	negative regulation of protein homodimerization activity
0.58	GO:0060426	lung vasculature development
0.58	GO:0001886	endothelial cell morphogenesis
0.57	GO:0045596	negative regulation of cell differentiation
0.56	GO:0045667	regulation of osteoblast differentiation
0.56	GO:0060425	lung morphogenesis
0.56	GO:0032963	collagen metabolic process
0.56	GO:0051241	negative regulation of multicellular organismal process
0.56	GO:0043392	negative regulation of DNA binding

0.68	GO:0046983	protein dimerization activity
0.55	GO:0043621	protein self-association
0.45	GO:0003677	DNA binding
0.44	GO:0003700	DNA binding transcription factor activity
0.40	GO:0008134	transcription factor binding
0.39	GO:0047485	protein N-terminus binding
0.39	GO:0070628	proteasome binding
0.39	GO:0008022	protein C-terminus binding
0.37	GO:0042802	identical protein binding

0.61	GO:0005634	nucleus
0.49	GO:0005794	Golgi apparatus
0.47	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.37	GO:0015630	microtubule cytoskeleton

sp|Q90X25|HXA13_CHICK
Homeobox protein Hox-A13
Search

HOXA13

0.81	LOW QUALITY PROTEIN: homeobox protein Hox-A13

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.42	GO:1902679	negative regulation of RNA biosynthetic process
0.38	GO:0007275	multicellular organism development
0.36	GO:2001055	positive regulation of mesenchymal cell apoptotic process
0.36	GO:0060847	endothelial cell fate specification
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:0001886	endothelial cell morphogenesis
0.35	GO:0033574	response to testosterone

0.62	GO:0043565	sequence-specific DNA binding
0.43	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.35	GO:0035326	enhancer binding
0.35	GO:0001012	RNA polymerase II regulatory region DNA binding
0.34	GO:0003690	double-stranded DNA binding
0.32	GO:0005515	protein binding

0.59

GO:0005634

nucleus

sp|Q90X67|SOCS3_CHICK
Suppressor of cytokine signaling 3
Search

SOCS3

0.97	Suppressor of cytokine signaling 3

0.82	GO:0007259	JAK-STAT cascade
0.75	GO:0043066	negative regulation of apoptotic process
0.68	GO:0016567	protein ubiquitination
0.65	GO:0046426	negative regulation of JAK-STAT cascade
0.60	GO:0046627	negative regulation of insulin receptor signaling pathway
0.57	GO:0060708	spongiotrophoblast differentiation
0.57	GO:0042509	regulation of tyrosine phosphorylation of STAT protein
0.56	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation
0.56	GO:0060670	branching involved in labyrinthine layer morphogenesis
0.56	GO:0060707	trophoblast giant cell differentiation

0.56	GO:0001784	phosphotyrosine residue binding
0.50	GO:0008269	JAK pathway signal transduction adaptor activity
0.49	GO:0005159	insulin-like growth factor receptor binding
0.49	GO:0004860	protein kinase inhibitor activity
0.42	GO:0005131	growth hormone receptor binding
0.33	GO:0097678	SOCS family protein binding
0.33	GO:0097677	STAT family protein binding
0.33	GO:0005070	SH3/SH2 adaptor activity
0.32	GO:0003779	actin binding
0.32	GO:0019901	protein kinase binding

0.45	GO:0005622	intracellular
0.32	GO:0005942	phosphatidylinositol 3-kinase complex

0.32

GO:0004715

tr|Q90XB2|Q90XB2_CHICK
Surfactant protein A
Search

0.87	Pulmonary surfactant-associated protein A

0.77	GO:0007585	respiratory gaseous exchange
0.62	GO:0008228	opsonization
0.52	GO:0002224	toll-like receptor signaling pathway
0.48	GO:0033189	response to vitamin A
0.48	GO:0071732	cellular response to nitric oxide
0.47	GO:0055093	response to hyperoxia
0.47	GO:0070741	response to interleukin-6
0.47	GO:0070849	response to epidermal growth factor
0.47	GO:0050766	positive regulation of phagocytosis
0.47	GO:0071260	cellular response to mechanical stimulus

0.63	GO:0030246	carbohydrate binding
0.47	GO:0046872	metal ion binding
0.44	GO:0005319	lipid transporter activity
0.40	GO:0005515	protein binding

0.79	GO:0005581	collagen trimer
0.67	GO:0005578	proteinaceous extracellular matrix
0.65	GO:0005615	extracellular space
0.55	GO:0042599	lamellar body
0.53	GO:0045334	clathrin-coated endocytic vesicle
0.50	GO:0005783	endoplasmic reticulum
0.47	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.47	GO:0005771	multivesicular body
0.46	GO:0031984	organelle subcompartment
0.30	GO:0044425	membrane part

sp|Q90XB3|OLIG2_CHICK
Oligodendrocyte transcription factor 2
Search

OLIG2

0.96	Oligodendrocyte lineage transcription factor 2

0.82	GO:0001708	cell fate specification
0.77	GO:0007417	central nervous system development
0.75	GO:0030182	neuron differentiation
0.72	GO:0021781	glial cell fate commitment
0.68	GO:0042552	myelination
0.64	GO:0048513	animal organ development
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0001764	neuron migration

0.67	GO:0046983	protein dimerization activity
0.55	GO:0140110	transcription regulator activity
0.50	GO:0071837	HMG box domain binding
0.45	GO:0042802	identical protein binding
0.35	GO:0003677	DNA binding

0.41	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.34	GO:0005667	transcription factor complex

sp|Q90XD2|SPEB_CHICK
Agmatinase, mitochondrial
Search

AGMAT

0.45	Agmatinase, mitochondrial

0.39	GO:0033388	putrescine biosynthetic process from arginine
0.38	GO:0008295	spermidine biosynthetic process
0.36	GO:0097055	agmatine biosynthetic process
0.33	GO:0006468	protein phosphorylation

0.75	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
0.54	GO:0046872	metal ion binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003723	RNA binding

0.36	GO:0070062	extracellular exosome
0.35	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.75

EC:3.5.3

GO:0016813

sp|Q90Y35|ZN622_CHICK
Zinc finger protein 622
Search

ZNF622

0.53	Zinc finger protein Yan

0.58	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress
0.55	GO:0046330	positive regulation of JNK cascade
0.53	GO:0043065	positive regulation of apoptotic process
0.52	GO:0033674	positive regulation of kinase activity
0.45	GO:0042273	ribosomal large subunit biogenesis
0.35	GO:0061709	reticulophagy

0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.33	GO:0005515	protein binding

0.50	GO:0005730	nucleolus
0.49	GO:0005829	cytosol
0.49	GO:0005794	Golgi apparatus
0.47	GO:0030687	preribosome, large subunit precursor
0.43	GO:0015934	large ribosomal subunit
0.34	GO:0030176	integral component of endoplasmic reticulum membrane

sp|Q90YB1|DNLI4_CHICK
DNA ligase 4
Search

LIG4

0.47	DNA ligase

0.80	GO:0051103	DNA ligation involved in DNA repair
0.67	GO:0071897	DNA biosynthetic process
0.66	GO:0006260	DNA replication
0.65	GO:0006310	DNA recombination
0.61	GO:0097680	double-strand break repair via classical nonhomologous end joining
0.61	GO:0006297	nucleotide-excision repair, DNA gap filling
0.60	GO:0002328	pro-B cell differentiation
0.59	GO:0016445	somatic diversification of immunoglobulins
0.59	GO:0002568	somatic diversification of T cell receptor genes
0.59	GO:0000012	single strand break repair

0.79	GO:0003910	DNA ligase (ATP) activity
0.56	GO:0008022	protein C-terminus binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046872	metal ion binding

0.62	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex
0.61	GO:0032807	DNA ligase IV complex
0.55	GO:0036464	cytoplasmic ribonucleoprotein granule
0.53	GO:0000793	condensed chromosome
0.50	GO:0005654	nucleoplasm
0.35	GO:0000784	nuclear chromosome, telomeric region

0.79

EC:6.5.1.1

GO:0003910

tr|Q90YB5|Q90YB5_CHICK
AvEna neural variant
Search

ENAH

0.84	Enabled homolog, transcript variant long

0.55	GO:0070358	actin polymerization-dependent cell motility
0.54	GO:0007411	axon guidance
0.52	GO:0001843	neural tube closure
0.52	GO:1990823	response to leukemia inhibitory factor
0.50	GO:0008154	actin polymerization or depolymerization
0.49	GO:0071345	cellular response to cytokine stimulus
0.47	GO:0046907	intracellular transport

0.64	GO:0050699	WW domain binding
0.54	GO:0005522	profilin binding
0.54	GO:0005199	structural constituent of cell wall
0.53	GO:0017124	SH3 domain binding
0.50	GO:0003779	actin binding

0.66	GO:0005925	focal adhesion
0.57	GO:0005829	cytosol
0.55	GO:0030175	filopodium
0.55	GO:0030027	lamellipodium
0.52	GO:0097517	contractile actin filament bundle
0.52	GO:0042641	actomyosin
0.51	GO:0045202	synapse
0.48	GO:0005886	plasma membrane

sp|Q90YC9|NBL1_CHICK
Neuroblastoma suppressor of tumorigenicity 1
Search

NBL1

0.97	Neuroblastoma suppressor of tumorigenicity 1

0.70	GO:0090027	negative regulation of monocyte chemotaxis
0.70	GO:0048263	determination of dorsal identity
0.70	GO:0035582	sequestering of BMP in extracellular matrix
0.62	GO:0045666	positive regulation of neuron differentiation
0.61	GO:0048812	neuron projection morphogenesis
0.60	GO:0010469	regulation of receptor activity
0.45	GO:0038098	sequestering of BMP from receptor via BMP binding
0.45	GO:0048752	semicircular canal morphogenesis
0.38	GO:0035148	tube formation

0.69	GO:0016015	morphogen activity
0.68	GO:0036122	BMP binding
0.43	GO:0042803	protein homodimerization activity
0.42	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q90YH8|ST7L_CHICK
Suppressor of tumorigenicity 7 protein-like
Search

ST7L

0.97	Suppression of tumorigenicity 7 like

0.54	GO:0030308	negative regulation of cell growth
0.34	GO:0030198	extracellular matrix organization
0.34	GO:0045595	regulation of cell differentiation
0.34	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process

0.34

GO:0003735

structural constituent of ribosome

0.34	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

sp|Q90YH9|TES_CHICK
Testin
Search

TES

0.92	Testis derived transcript

0.76	GO:0042127	regulation of cell proliferation
0.52	GO:0048523	negative regulation of cellular process
0.36	GO:0001755	neural crest cell migration
0.33	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling

0.63	GO:0008270	zinc ion binding
0.54	GO:0045296	cadherin binding
0.34	GO:0003723	RNA binding

0.61	GO:0005925	focal adhesion
0.48	GO:0005829	cytosol
0.44	GO:0043234	protein complex
0.42	GO:0005886	plasma membrane
0.35	GO:0005938	cell cortex
0.34	GO:0005634	nucleus

sp|Q90YI0|IL6_CHICK
Interleukin-6
Search

IL6

0.80	Interleukin-6

0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.57	GO:0001781	neutrophil apoptotic process
0.57	GO:0032966	negative regulation of collagen biosynthetic process
0.56	GO:0051024	positive regulation of immunoglobulin secretion
0.55	GO:0070102	interleukin-6-mediated signaling pathway
0.55	GO:0002675	positive regulation of acute inflammatory response
0.54	GO:0010574	regulation of vascular endothelial growth factor production
0.54	GO:0048661	positive regulation of smooth muscle cell proliferation
0.54	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein

0.86	GO:0005138	interleukin-6 receptor binding
0.80	GO:0005125	cytokine activity
0.50	GO:0008083	growth factor activity

0.66	GO:0005576	extracellular region
0.56	GO:0005896	interleukin-6 receptor complex

sp|Q90YI1|OCX32_CHICK
Ovocalyxin-32
Search

RARRES1

0.96	Retinoic acid receptor responder protein 1

0.85

GO:0031214

biomineral tissue development

0.87	GO:0035805	egg coat
0.76	GO:0005578	proteinaceous extracellular matrix
0.73	GO:0005615	extracellular space

sp|Q90YJ9|CLAT_CHICK
Choline O-acetyltransferase
Search

CHAT

0.96	Choline O-acetyltransferase a

0.57	GO:0060416	response to growth hormone
0.43	GO:0007626	locomotory behavior
0.39	GO:0042136	neurotransmitter biosynthetic process
0.38	GO:0007529	establishment of synaptic specificity at neuromuscular junction
0.38	GO:0043179	rhythmic excitation
0.37	GO:0007268	chemical synaptic transmission
0.37	GO:0007622	rhythmic behavior
0.36	GO:0016358	dendrite development
0.36	GO:0030534	adult behavior
0.36	GO:0007517	muscle organ development

0.62	GO:0016746	transferase activity, transferring acyl groups
0.35	GO:0033265	choline binding

0.37	GO:0097458	neuron part
0.36	GO:0044297	cell body
0.35	GO:0120025	plasma membrane bounded cell projection
0.34	GO:0044456	synapse part
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0044444	cytoplasmic part

0.62

EC:2.3

GO:0016746

sp|Q90YK5|HPSE_CHICK
Heparanase
Search

HPSE

0.97	Heparanase

0.60	GO:0030200	heparan sulfate proteoglycan catabolic process
0.59	GO:0060055	angiogenesis involved in wound healing
0.58	GO:0033690	positive regulation of osteoblast proliferation
0.57	GO:0051797	regulation of hair follicle development
0.57	GO:0010575	positive regulation of vascular endothelial growth factor production
0.57	GO:0042635	positive regulation of hair cycle
0.56	GO:0030194	positive regulation of blood coagulation
0.56	GO:0045684	positive regulation of epidermis development
0.55	GO:0051897	positive regulation of protein kinase B signaling
0.55	GO:0007160	cell-matrix adhesion

0.66	GO:0016798	hydrolase activity, acting on glycosyl bonds
0.59	GO:0043394	proteoglycan binding
0.48	GO:0046983	protein dimerization activity
0.39	GO:1901681	sulfur compound binding
0.36	GO:0043168	anion binding
0.34	GO:0047293	4-hydroxybenzoate nonaprenyltransferase activity
0.34	GO:0002083	4-hydroxybenzoate decaprenyltransferase activity
0.33	GO:0004386	helicase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.53	GO:0005764	lysosome
0.53	GO:0045121	membrane raft
0.48	GO:0005654	nucleoplasm
0.48	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0098852	lytic vacuole membrane
0.35	GO:0035580	specific granule lumen
0.35	GO:0005775	vacuolar lumen
0.34	GO:0031305	integral component of mitochondrial inner membrane
0.32	GO:0005886	plasma membrane

0.66

EC:3.2

GO:0016798

sp|Q90Z16|OPTN_CHICK
Optineurin
Search

OPTN

0.97	Optineurin

0.77	GO:0006914	autophagy
0.69	GO:0016192	vesicle-mediated transport
0.59	GO:0090161	Golgi ribbon formation
0.57	GO:0001920	negative regulation of receptor recycling
0.57	GO:0061734	parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
0.57	GO:0072600	establishment of protein localization to Golgi
0.57	GO:1904417	positive regulation of xenophagy
0.55	GO:0034620	cellular response to unfolded protein
0.54	GO:0061951	establishment of protein localization to plasma membrane
0.53	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling

0.85	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding
0.53	GO:0008022	protein C-terminus binding
0.52	GO:0017137	Rab GTPase binding
0.52	GO:0030674	protein binding, bridging
0.49	GO:0042802	identical protein binding
0.36	GO:0046872	metal ion binding
0.35	GO:0001155	TFIIIA-class transcription factor binding
0.34	GO:0043130	ubiquitin binding
0.32	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0003676	nucleic acid binding

0.72	GO:0031410	cytoplasmic vesicle
0.71	GO:0005794	Golgi apparatus
0.52	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0031984	organelle subcompartment
0.47	GO:0005829	cytosol
0.43	GO:0005776	autophagosome
0.40	GO:0005634	nucleus
0.34	GO:0043025	neuronal cell body
0.34	GO:0030424	axon
0.34	GO:0098805	whole membrane

0.32

GO:0004674

tr|Q90Z54|Q90Z54_CHICK
Caudal-type homeobox protein CDXB
Search

0.96	Caudal-type homeobox protein CDXB

0.68	GO:0007275	multicellular organism development
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.48	GO:0009653	anatomical structure morphogenesis
0.46	GO:0003006	developmental process involved in reproduction
0.46	GO:0060429	epithelium development
0.45	GO:0030154	cell differentiation
0.45	GO:1902679	negative regulation of RNA biosynthetic process
0.45	GO:0048522	positive regulation of cellular process

0.57	GO:0043565	sequence-specific DNA binding
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.47	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.42	GO:0035326	enhancer binding
0.42	GO:0003682	chromatin binding
0.42	GO:0003714	transcription corepressor activity
0.33	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.42	GO:0017053	transcriptional repressor complex
0.41	GO:0000793	condensed chromosome
0.38	GO:0043233	organelle lumen
0.37	GO:0043234	protein complex
0.36	GO:0044446	intracellular organelle part

sp|Q90Z72|NFIL3_CHICK
Nuclear factor interleukin-3-regulated protein
Search

NFIL3

0.97	Interleukin 3 regulated nuclear factor

0.81	GO:0007623	circadian rhythm
0.74	GO:0006366	transcription by RNA polymerase II
0.73	GO:0006955	immune response
0.60	GO:0071353	cellular response to interleukin-4
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0051253	negative regulation of RNA metabolic process
0.52	GO:0010558	negative regulation of macromolecule biosynthetic process
0.52	GO:0031327	negative regulation of cellular biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0003714	transcription corepressor activity
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm

tr|Q90ZD4|Q90ZD4_CHICK
Interferon regulatory factor 7
Search

IRF7

0.77	Interferon regulatory factor 7

0.60	GO:0045351	type I interferon biosynthetic process
0.59	GO:0060340	positive regulation of type I interferon-mediated signaling pathway
0.59	GO:0034127	regulation of MyD88-independent toll-like receptor signaling pathway
0.59	GO:0032607	interferon-alpha production
0.58	GO:0032608	interferon-beta production
0.58	GO:0032727	positive regulation of interferon-alpha production
0.58	GO:0032728	positive regulation of interferon-beta production
0.57	GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway
0.56	GO:0006351	transcription, DNA-templated
0.56	GO:0006355	regulation of transcription, DNA-templated

0.75	GO:0044212	transcription regulatory region DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.51	GO:1990837	sequence-specific double-stranded DNA binding
0.40	GO:0019904	protein domain specific binding
0.39	GO:0042803	protein homodimerization activity

0.60	GO:0005634	nucleus
0.49	GO:0005829	cytosol
0.47	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.34	GO:0005768	endosome
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.33	GO:0048471	perinuclear region of cytoplasm

sp|Q90ZD5|CRDL1_CHICK
Chordin-like protein 1
Search

CHRDL1

0.97	Chordin like 1

0.80	GO:0030514	negative regulation of BMP signaling pathway
0.79	GO:0048749	compound eye development
0.47	GO:0001503	ossification
0.44	GO:0030154	cell differentiation
0.43	GO:0007399	nervous system development
0.41	GO:0009953	dorsal/ventral pattern formation
0.40	GO:0030509	BMP signaling pathway
0.39	GO:0043687	post-translational protein modification
0.38	GO:0051216	cartilage development
0.31	GO:0055114	oxidation-reduction process

0.34	GO:0005515	protein binding
0.31	GO:0016491	oxidoreductase activity
0.31	GO:0046872	metal ion binding

0.44	GO:0005576	extracellular region
0.39	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

0.31

GO:0016491

sp|Q90ZF9|CENPH_CHICK
Centromere protein H
Search

CENPH

0.70	Centromere protein H

0.84

GO:0051382

kinetochore assembly

0.81

GO:0043515

kinetochore binding

0.78	GO:0000776	kinetochore
0.74	GO:0000779	condensed chromosome, centromeric region
0.68	GO:0005730	nucleolus

tr|Q90ZG0|Q90ZG0_CHICK
Peptidylprolyl isomerase
Search

0.66	Peptidyl-prolyl cis-trans isomerase FKBP1A

0.86	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity
0.85	GO:1990000	amyloid fibril formation
0.85	GO:0007183	SMAD protein complex assembly
0.85	GO:0060347	heart trabecula formation
0.85	GO:0031000	response to caffeine
0.84	GO:1902991	regulation of amyloid precursor protein catabolic process
0.83	GO:0032925	regulation of activin receptor signaling pathway
0.83	GO:0042098	T cell proliferation
0.82	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.80	GO:0032092	positive regulation of protein binding

0.85	GO:0048185	activin binding
0.81	GO:0005528	FK506 binding
0.80	GO:0044325	ion channel binding
0.80	GO:0046332	SMAD binding
0.80	GO:0019855	calcium channel inhibitor activity
0.73	GO:0034713	type I transforming growth factor beta receptor binding
0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.71	GO:0030544	Hsp70 protein binding
0.71	GO:0042803	protein homodimerization activity
0.60	GO:0019899	enzyme binding

0.88	GO:1990425	ryanodine receptor complex
0.81	GO:0031312	extrinsic component of organelle membrane
0.79	GO:0030018	Z disc
0.76	GO:0098562	cytoplasmic side of membrane
0.75	GO:0014802	terminal cisterna
0.72	GO:0070062	extracellular exosome
0.69	GO:0043679	axon terminus
0.69	GO:0005829	cytosol

0.72

GO:0003755

sp|Q90ZK6|ACVR1_CHICK
Activin receptor type-1
Search

ACVR1

0.61	Serine/threonine-protein kinase receptor

0.80	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.66	GO:0023014	signal transduction by protein phosphorylation
0.60	GO:0061445	endocardial cushion cell fate commitment
0.59	GO:0003289	atrial septum primum morphogenesis
0.59	GO:2000017	positive regulation of determination of dorsal identity
0.59	GO:0003274	endocardial cushion fusion
0.59	GO:0060923	cardiac muscle cell fate commitment
0.58	GO:1905007	positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
0.58	GO:0003183	mitral valve morphogenesis
0.57	GO:0032926	negative regulation of activin receptor signaling pathway

0.82	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.79	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.58	GO:0048185	activin binding
0.58	GO:0050431	transforming growth factor beta binding
0.55	GO:0046332	SMAD binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.51	GO:0042803	protein homodimerization activity

0.59	GO:0048179	activin receptor complex
0.53	GO:0045177	apical part of cell
0.42	GO:0070724	BMP receptor complex
0.39	GO:0005938	cell cortex

0.82

GO:0004675

sp|Q90ZN1|NR13_CHICK
Anti-apoptotic protein NR13
Search

0.87	Anti-apoptotic protein NR13

0.73	GO:0042981	regulation of apoptotic process
0.67	GO:0006915	apoptotic process
0.63	GO:0038034	signal transduction in absence of ligand
0.57	GO:1902532	negative regulation of intracellular signal transduction
0.57	GO:0043069	negative regulation of programmed cell death
0.53	GO:0007166	cell surface receptor signaling pathway
0.49	GO:0006974	cellular response to DNA damage stimulus
0.48	GO:0035556	intracellular signal transduction

0.55	GO:0042803	protein homodimerization activity
0.55	GO:0046982	protein heterodimerization activity

0.56	GO:0005741	mitochondrial outer membrane
0.50	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q90ZT4|Q90ZT4_CHICK
OL-protocadherin isoform
Search

0.90	OL-protocadherin isoform

0.77	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.50	GO:0021794	thalamus development
0.49	GO:0048339	paraxial mesoderm development
0.48	GO:0001756	somitogenesis
0.40	GO:0007267	cell-cell signaling

0.69

GO:0005509

calcium ion binding

0.55	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q91000|Q91000_CHICK
Trans Golgi network protease furin
Search

FURIN

0.95	Furin, paired basic amino acid cleaving enzyme

0.61	GO:0006508	proteolysis
0.59	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process
0.59	GO:0032902	nerve growth factor production
0.58	GO:0032911	negative regulation of transforming growth factor beta1 production
0.58	GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process
0.52	GO:0008283	cell proliferation
0.51	GO:0010951	negative regulation of endopeptidase activity
0.51	GO:0042445	hormone metabolic process
0.49	GO:0051604	protein maturation
0.48	GO:0032940	secretion by cell

0.69	GO:0004252	serine-type endopeptidase activity
0.58	GO:0048406	nerve growth factor binding
0.55	GO:0002020	protease binding
0.52	GO:0042277	peptide binding
0.52	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0046872	metal ion binding
0.34	GO:0043140	ATP-dependent 3'-5' DNA helicase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0097367	carbohydrate derivative binding

0.54	GO:0030140	trans-Golgi network transport vesicle
0.53	GO:0098857	membrane microdomain
0.52	GO:0005802	trans-Golgi network
0.51	GO:0009986	cell surface
0.50	GO:0000139	Golgi membrane
0.48	GO:0005783	endoplasmic reticulum
0.39	GO:0010008	endosome membrane
0.37	GO:0005576	extracellular region
0.35	GO:0005796	Golgi lumen
0.35	GO:0030659	cytoplasmic vesicle membrane

0.69

GO:0004252

sp|Q91009|NTRK1_CHICK
High affinity nerve growth factor receptor (Fragment)
Search

NTRK1

0.66	Tyrosine-protein kinase receptor

0.81	GO:0038179	neurotrophin signaling pathway
0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.59	GO:0061368	behavioral response to formalin induced pain
0.58	GO:0060385	axonogenesis involved in innervation
0.57	GO:1990090	cellular response to nerve growth factor stimulus
0.57	GO:0010975	regulation of neuron projection development
0.56	GO:0051965	positive regulation of synapse assembly
0.56	GO:0048485	sympathetic nervous system development
0.56	GO:0042490	mechanoreceptor differentiation

0.83	GO:0005030	neurotrophin receptor activity
0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.60	GO:0043121	neurotrophin binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.51	GO:0042803	protein homodimerization activity
0.41	GO:0022832	voltage-gated channel activity
0.40	GO:0022839	ion gated channel activity

0.65	GO:0005887	integral component of plasma membrane
0.54	GO:0043235	receptor complex
0.53	GO:0005769	early endosome
0.53	GO:0030424	axon
0.52	GO:0005770	late endosome
0.50	GO:0009986	cell surface
0.37	GO:0043679	axon terminus
0.37	GO:0014069	postsynaptic density
0.37	GO:0045211	postsynaptic membrane
0.35	GO:0005829	cytosol

0.80

GO:0004714

sp|Q91012|T22D1_CHICK
TSC22 domain family protein 1
Search

TSC22D1

0.93	Putative thyroid hormone receptor-associated protein complex subunit

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.36	GO:0006351	transcription, DNA-templated
0.34	GO:0008284	positive regulation of cell proliferation
0.34	GO:0043065	positive regulation of apoptotic process
0.34	GO:0043066	negative regulation of apoptotic process
0.32	GO:0051254	positive regulation of RNA metabolic process
0.32	GO:0010557	positive regulation of macromolecule biosynthetic process
0.32	GO:0031328	positive regulation of cellular biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005515	protein binding
0.32	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.41	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm

sp|Q91018|PROX1_CHICK
Prospero homeobox protein 1
Search

PROX1

0.97	Prospero homeobox protein 1

0.64	GO:0001946	lymphangiogenesis
0.64	GO:0060849	regulation of transcription involved in lymphatic endothelial cell fate commitment
0.63	GO:0070309	lens fiber cell morphogenesis
0.63	GO:1904252	negative regulation of bile acid metabolic process
0.63	GO:2000979	positive regulation of forebrain neuron differentiation
0.63	GO:0090425	acinar cell differentiation
0.63	GO:0002194	hepatocyte cell migration
0.63	GO:0070365	hepatocyte differentiation
0.62	GO:0061114	branching involved in pancreas morphogenesis
0.62	GO:0060414	aorta smooth muscle tissue morphogenesis

0.63	GO:0050692	DBD domain binding
0.63	GO:0050693	LBD domain binding
0.61	GO:0016922	ligand-dependent nuclear receptor binding
0.58	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.57	GO:0001046	core promoter sequence-specific DNA binding
0.57	GO:0003714	transcription corepressor activity
0.48	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.54	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm

sp|Q91025|VIT3_CHICK
Vitellogenin-3 (Fragments)
Search

0.10	Vitellogenin-3 (Fragments)

0.74

GO:0006869

lipid transport

0.77	GO:0005319	lipid transporter activity
0.46	GO:0045735	nutrient reservoir activity

0.30

GO:0031224

intrinsic component of membrane

sp|Q91029|WNT1_CHICK
Protein Wnt-1 (Fragment)
Search

WNT1

0.86	Proto-oncogene Wnt-1

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.62	GO:0061184	positive regulation of dermatome development
0.62	GO:0036520	astrocyte-dopaminergic neuron signaling
0.61	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway
0.60	GO:0030579	ubiquitin-dependent SMAD protein catabolic process
0.60	GO:0060061	Spemann organizer formation
0.60	GO:0010592	positive regulation of lamellipodium assembly
0.59	GO:0090344	negative regulation of cell aging
0.59	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

0.73	GO:0005102	receptor binding
0.53	GO:0044212	transcription regulatory region DNA binding
0.53	GO:0030545	receptor regulator activity
0.53	GO:0019904	protein domain specific binding
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0008270	zinc ion binding

0.76	GO:0005578	proteinaceous extracellular matrix
0.52	GO:0009986	cell surface
0.45	GO:0005615	extracellular space
0.40	GO:0005737	cytoplasm
0.36	GO:1990909	Wnt signalosome
0.35	GO:0012505	endomembrane system
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:1903561	extracellular vesicle
0.34	GO:0012506	vesicle membrane
0.34	GO:0097708	intracellular vesicle

0.33

GO:0004222

sp|Q91035|SHH_CHICK
Sonic hedgehog protein
Search

SHH

0.84	Sonic hedgehog protein A

0.74	GO:0007267	cell-cell signaling
0.72	GO:0016539	intein-mediated protein splicing
0.69	GO:0007275	multicellular organism development
0.56	GO:0033084	regulation of immature T cell proliferation in thymus
0.56	GO:0033089	positive regulation of T cell differentiation in thymus
0.56	GO:0045880	positive regulation of smoothened signaling pathway
0.55	GO:0046639	negative regulation of alpha-beta T cell differentiation
0.55	GO:0002053	positive regulation of mesenchymal cell proliferation
0.55	GO:0007224	smoothened signaling pathway
0.55	GO:0046638	positive regulation of alpha-beta T cell differentiation

0.59	GO:0008233	peptidase activity
0.57	GO:0005113	patched binding
0.52	GO:0043237	laminin-1 binding
0.51	GO:0046872	metal ion binding
0.46	GO:0005539	glycosaminoglycan binding
0.38	GO:0016015	morphogen activity
0.32	GO:0022857	transmembrane transporter activity

0.68	GO:0005615	extracellular space
0.52	GO:0005886	plasma membrane
0.49	GO:0005578	proteinaceous extracellular matrix
0.48	GO:0098857	membrane microdomain
0.46	GO:0009986	cell surface
0.36	GO:0005622	intracellular
0.35	GO:0012505	endomembrane system
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.34	GO:0030424	axon

0.59

GO:0008233

sp|Q91044|NTRK3_CHICK
NT-3 growth factor receptor
Search

NTRK3

0.67	Tyrosine-protein kinase receptor

0.78	GO:0038179	neurotrophin signaling pathway
0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.51	GO:0048687	positive regulation of sprouting of injured axon
0.51	GO:0048690	regulation of axon extension involved in regeneration
0.50	GO:2000251	positive regulation of actin cytoskeleton reorganization
0.50	GO:0050927	positive regulation of positive chemotaxis
0.50	GO:0032148	activation of protein kinase B activity
0.50	GO:0070306	lens fiber cell differentiation
0.49	GO:0045773	positive regulation of axon extension

0.80	GO:0005030	neurotrophin receptor activity
0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0002039	p53 binding
0.36	GO:0043121	neurotrophin binding
0.34	GO:0004675	transmembrane receptor protein serine/threonine kinase activity

0.65	GO:0005887	integral component of plasma membrane
0.46	GO:0043235	receptor complex
0.37	GO:0005737	cytoplasm
0.34	GO:0098588	bounding membrane of organelle
0.33	GO:0031984	organelle subcompartment
0.33	GO:0012505	endomembrane system
0.32	GO:0043231	intracellular membrane-bounded organelle

0.80

GO:0004714

sp|Q91048|PTK7_CHICK
Inactive tyrosine-protein kinase 7
Search

PTK7

0.96	Inactive tyrosine-protein kinase 7

0.85	GO:0060071	Wnt signaling pathway, planar cell polarity pathway
0.85	GO:0060026	convergent extension
0.85	GO:0001736	establishment of planar polarity
0.63	GO:0006468	protein phosphorylation
0.56	GO:0018212	peptidyl-tyrosine modification
0.56	GO:0003401	axis elongation
0.55	GO:0060484	lung-associated mesenchyme development
0.55	GO:0090178	regulation of establishment of planar polarity involved in neural tube closure
0.55	GO:0045198	establishment of epithelial cell apical/basal polarity
0.54	GO:0090103	cochlea morphogenesis

0.86	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway
0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.35	GO:0004888	transmembrane signaling receptor activity
0.34	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0000987	proximal promoter sequence-specific DNA binding

0.66	GO:0005887	integral component of plasma membrane
0.50	GO:0005911	cell-cell junction
0.35	GO:0005925	focal adhesion
0.34	GO:0005634	nucleus

sp|Q91049|OCLN_CHICK
Occludin
Search

OCLN

0.95	Occludin antigen

0.84	GO:0070830	bicellular tight junction assembly
0.40	GO:0070673	response to interleukin-18
0.39	GO:0071356	cellular response to tumor necrosis factor
0.35	GO:2000810	regulation of bicellular tight junction assembly
0.33	GO:0006414	translational elongation
0.33	GO:0006461	protein complex assembly
0.33	GO:0032259	methylation

0.49	GO:0019904	protein domain specific binding
0.35	GO:0008119	thiopurine S-methyltransferase activity
0.33	GO:0003746	translation elongation factor activity

0.79	GO:0005923	bicellular tight junction
0.54	GO:0016327	apicolateral plasma membrane
0.51	GO:0016324	apical plasma membrane
0.51	GO:0030139	endocytic vesicle
0.39	GO:0016328	lateral plasma membrane
0.35	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

0.35

EC:2.1.1.67

GO:0008119

sp|Q91348|F26L_CHICK
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
Search

PFKFB1

0.88	6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase

0.83	GO:0006003	fructose 2,6-bisphosphate metabolic process
0.82	GO:0006000	fructose metabolic process
0.74	GO:0046835	carbohydrate phosphorylation
0.46	GO:0016311	dephosphorylation
0.40	GO:0033133	positive regulation of glucokinase activity
0.39	GO:0033762	response to glucagon
0.39	GO:0031100	animal organ regeneration
0.39	GO:0051591	response to cAMP
0.39	GO:0051384	response to glucocorticoid
0.38	GO:0032868	response to insulin

0.84	GO:0003873	6-phosphofructo-2-kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0042802	identical protein binding
0.40	GO:0070095	fructose-6-phosphate binding
0.37	GO:0019900	kinase binding
0.35	GO:0003968	RNA-directed 5'-3' RNA polymerase activity
0.33	GO:0004930	G-protein coupled receptor activity

0.54	GO:0043540	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex
0.30	GO:0016021	integral component of membrane

0.84	EC:2.7.1.105	GO:0003873
0.84	KEGG:R02732	GO:0003873

sp|Q91379|NR2E1_CHICK
Nuclear receptor subfamily 2 group E member 1
Search

NR2E1

0.96	Nuclear receptor TLX

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.60	GO:0060164	regulation of timing of neuron differentiation
0.59	GO:0021764	amygdala development
0.59	GO:0021960	anterior commissure morphogenesis
0.58	GO:0048712	negative regulation of astrocyte differentiation
0.58	GO:0002118	aggressive behavior
0.58	GO:0021819	layer formation in cerebral cortex
0.58	GO:0021542	dentate gyrus development
0.58	GO:0097659	nucleic acid-templated transcription
0.58	GO:0021895	cerebral cortex neuron differentiation

0.79	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0042826	histone deacetylase binding
0.32	GO:0015631	tubulin binding

0.61	GO:0005634	nucleus
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q91955|MTPN_CHICK
Myotrophin
Search

MTPN

0.96	Myotrophin

0.79	GO:0014742	positive regulation of muscle hypertrophy
0.78	GO:0010611	regulation of cardiac muscle hypertrophy
0.77	GO:2000812	regulation of barbed-end actin filament capping
0.72	GO:0008361	regulation of cell size
0.51	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.51	GO:0030307	positive regulation of cell growth
0.48	GO:0021684	cerebellar granular layer formation
0.48	GO:0043403	skeletal muscle tissue regeneration
0.47	GO:0021533	cell differentiation in hindbrain
0.47	GO:0051247	positive regulation of protein metabolic process

0.46	GO:0002039	p53 binding
0.44	GO:0018024	histone-lysine N-methyltransferase activity
0.40	GO:0043565	sequence-specific DNA binding
0.39	GO:0008270	zinc ion binding
0.38	GO:0019901	protein kinase binding
0.36	GO:0008318	protein prenyltransferase activity
0.34	GO:0008081	phosphoric diester hydrolase activity

0.74	GO:0008290	F-actin capping protein complex
0.51	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0030424	axon
0.47	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.41	GO:0070062	extracellular exosome
0.40	GO:0005694	chromosome
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.44

EC:2.1.1.43

GO:0018024

sp|Q91957|XIRP1_CHICK
Xin actin-binding repeat-containing protein 1
Search

XIRP1

0.66	Xin actin-binding repeat-containing protein 1

0.79	GO:0007507	heart development
0.73	GO:0030036	actin cytoskeleton organization
0.51	GO:0060415	muscle tissue morphogenesis
0.50	GO:0045216	cell-cell junction organization
0.50	GO:0014706	striated muscle tissue development
0.42	GO:0032091	negative regulation of protein binding
0.33	GO:0055002	striated muscle cell development
0.33	GO:0007219	Notch signaling pathway
0.33	GO:0010927	cellular component assembly involved in morphogenesis
0.33	GO:0008285	negative regulation of cell proliferation

0.73	GO:0003779	actin binding
0.52	GO:0051393	alpha-actinin binding
0.37	GO:0046872	metal ion binding
0.33	GO:0031005	filamin binding
0.32	GO:0003723	RNA binding

0.74	GO:0030054	cell junction
0.56	GO:0031941	filamentous actin
0.56	GO:0097517	contractile actin filament bundle
0.56	GO:0042641	actomyosin
0.51	GO:0030018	Z disc

tr|Q91967|Q91967_CHICK
Gnot1 homeodomain protein
Search

0.90	homeobox protein notochord

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:0014028	notochord formation
0.45	GO:0048331	axial mesoderm structural organization
0.44	GO:0048321	axial mesodermal cell differentiation
0.44	GO:0021982	pineal gland development
0.44	GO:0035775	pronephric glomerulus morphogenesis
0.43	GO:0021508	floor plate formation
0.43	GO:0003160	endocardium morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.33	GO:0000774	adenyl-nucleotide exchange factor activity
0.33	GO:0051087	chaperone binding
0.33	GO:0042803	protein homodimerization activity
0.32	GO:0009055	electron transfer activity

0.61	GO:0005634	nucleus
0.33	GO:0005759	mitochondrial matrix
0.30	GO:0031224	intrinsic component of membrane

sp|Q91974|IKBA_CHICK
NF-kappa-B inhibitor alpha
Search

NFKBIA

0.97	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

0.86	GO:0007253	cytoplasmic sequestering of NF-kappaB
0.85	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway
0.85	GO:0010745	negative regulation of macrophage derived foam cell differentiation
0.85	GO:0010875	positive regulation of cholesterol efflux
0.85	GO:0010888	negative regulation of lipid storage
0.85	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway
0.83	GO:0035994	response to muscle stretch
0.83	GO:0032495	response to muramyl dipeptide
0.82	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.82	GO:0007249	I-kappaB kinase/NF-kappaB signaling

0.84	GO:0051059	NF-kappaB binding
0.82	GO:0008139	nuclear localization sequence binding
0.76	GO:0031625	ubiquitin protein ligase binding
0.71	GO:0042802	identical protein binding
0.43	GO:0031072	heat shock protein binding
0.43	GO:0032403	protein complex binding
0.34	GO:0016301	kinase activity

0.66	GO:0005829	cytosol
0.59	GO:0005634	nucleus
0.54	GO:0005886	plasma membrane
0.44	GO:0033256	I-kappaB/NF-kappaB complex

sp|Q91975|DBX2_CHICK
Homeobox protein DBX2 (Fragment)
Search

DBX2

0.97	Homeobox protein DBX2

0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.36	GO:0007275	multicellular organism development

0.64

GO:0043565

sequence-specific DNA binding

0.61

GO:0005634

nucleus

sp|Q91987|NTRK2_CHICK
BDNF/NT-3 growth factors receptor
Search

NTRK2

0.67	Tyrosine-protein kinase receptor

0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.75	GO:0038179	neurotrophin signaling pathway
0.59	GO:0099538	synaptic signaling via neuropeptide
0.58	GO:0010975	regulation of neuron projection development
0.58	GO:0099550	trans-synaptic signaling, modulating synaptic transmission
0.57	GO:0014047	glutamate secretion
0.57	GO:0046548	retinal rod cell development
0.56	GO:2000811	negative regulation of anoikis
0.56	GO:0048935	peripheral nervous system neuron development

0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.77	GO:0005030	neurotrophin receptor activity
0.58	GO:0048403	brain-derived neurotrophic factor binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.47	GO:0022832	voltage-gated channel activity
0.46	GO:0022839	ion gated channel activity
0.46	GO:0008381	mechanosensitive ion channel activity

0.65	GO:0005887	integral component of plasma membrane
0.55	GO:0043195	terminal bouton
0.54	GO:0014069	postsynaptic density
0.52	GO:0005769	early endosome
0.52	GO:0045211	postsynaptic membrane
0.51	GO:0043235	receptor complex
0.47	GO:0005829	cytosol
0.39	GO:0010008	endosome membrane
0.37	GO:0044297	cell body
0.35	GO:0060076	excitatory synapse

0.80

GO:0004714

sp|Q91998|BRN3_CHICK
Brain-specific homeobox/POU domain protein 3
Search

0.54	POU domain, class 4, transcription factor 3

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0007605	sensory perception of sound
0.51	GO:0048839	inner ear development
0.46	GO:0007420	brain development
0.44	GO:0045672	positive regulation of osteoclast differentiation
0.43	GO:0051355	proprioception involved in equilibrioception
0.42	GO:0003223	ventricular compact myocardium morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.42	GO:0003714	transcription corepressor activity
0.41	GO:0001012	RNA polymerase II regulatory region DNA binding
0.41	GO:0003682	chromatin binding
0.41	GO:0035326	enhancer binding
0.40	GO:0003690	double-stranded DNA binding
0.40	GO:0003713	transcription coactivator activity
0.39	GO:0051020	GTPase binding
0.39	GO:0003697	single-stranded DNA binding

0.61	GO:0005634	nucleus
0.39	GO:0043005	neuron projection
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:0000785	chromatin
0.35	GO:0005737	cytoplasm

sp|Q92010|ZBT14_CHICK
Zinc finger and BTB domain-containing protein 14
Search

ZBTB14

0.97	Zinc finger and BTB domain-containing protein 14

0.56	GO:0060976	coronary vasculature development
0.56	GO:0003170	heart valve development
0.55	GO:0003279	cardiac septum development
0.52	GO:0000122	negative regulation of transcription by RNA polymerase II
0.35	GO:0007016	cytoskeletal anchoring at plasma membrane
0.35	GO:0030866	cortical actin cytoskeleton organization
0.35	GO:0001558	regulation of cell growth
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0061411	positive regulation of transcription from RNA polymerase II promoter in response to cold
0.34	GO:0061403	positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress

0.55	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding
0.33	GO:0005198	structural molecule activity
0.32	GO:0003924	GTPase activity
0.32	GO:0005525	GTP binding
0.32	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.32	GO:0004842	ubiquitin-protein transferase activity

0.57	GO:0016235	aggresome
0.50	GO:0005730	nucleolus
0.49	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.35	GO:0005911	cell-cell junction
0.34	GO:0005856	cytoskeleton
0.33	GO:0005886	plasma membrane
0.32	GO:0031463	Cul3-RING ubiquitin ligase complex

0.32

GO:0004842

sp|Q92056|ASMT_CHICK
Acetylserotonin O-methyltransferase
Search

ASMT

0.90	Acetylserotonin O-methyltransferase

0.63	GO:0032259	methylation
0.52	GO:0030187	melatonin biosynthetic process
0.34	GO:0043484	regulation of RNA splicing
0.34	GO:0046219	indolalkylamine biosynthetic process
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.73	GO:0008171	O-methyltransferase activity
0.47	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.44	GO:0042803	protein homodimerization activity
0.42	GO:0047429	nucleoside-triphosphate diphosphatase activity
0.34	GO:0051018	protein kinase A binding
0.34	GO:0008172	S-methyltransferase activity
0.32	GO:0003676	nucleic acid binding

0.37	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.73

GO:0008171

sp|Q92058|PPBT_CHICK
Alkaline phosphatase, tissue-nonspecific isozyme
Search

ALPL

0.47	Alkaline phosphatase, tissue-nonspecific isozyme

0.68	GO:0016311	dephosphorylation
0.56	GO:0033280	response to vitamin D
0.55	GO:0001958	endochondral ossification
0.50	GO:0071407	cellular response to organic cyclic compound
0.50	GO:0003006	developmental process involved in reproduction
0.49	GO:0046677	response to antibiotic
0.44	GO:0009612	response to mechanical stimulus
0.41	GO:0071529	cementum mineralization
0.39	GO:0051384	response to glucocorticoid
0.39	GO:0032496	response to lipopolysaccharide

0.82	GO:0004035	alkaline phosphatase activity
0.43	GO:0016462	pyrophosphatase activity
0.37	GO:0002020	protease binding
0.35	GO:0046872	metal ion binding

0.56	GO:0065010	extracellular membrane-bounded organelle
0.50	GO:0005578	proteinaceous extracellular matrix
0.42	GO:0005886	plasma membrane
0.41	GO:0031225	anchored component of membrane
0.37	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.82

EC:3.1.3.1

GO:0004035

sp|Q92060|MAOX_CHICK
NADP-dependent malic enzyme (Fragment)
Search

0.58	NADP-dependent malic enzyme (Fragment)

0.52

GO:0055114

oxidation-reduction process

0.83	GO:0004473	malate dehydrogenase (decarboxylating) (NADP+) activity
0.79	GO:0008948	oxaloacetate decarboxylase activity

0.49

GO:0005737

cytoplasm

0.83	EC:1.1.1.40	GO:0004473
0.83	KEGG:R00216	GO:0004473

tr|Q92071|Q92071_CHICK
Integrin beta
Search

ITGB3

0.67	Integrin beta

0.86	GO:0060055	angiogenesis involved in wound healing
0.85	GO:0070527	platelet aggregation
0.85	GO:0007044	cell-substrate junction assembly
0.82	GO:0007160	cell-matrix adhesion
0.80	GO:0007229	integrin-mediated signaling pathway
0.79	GO:0030334	regulation of cell migration
0.55	GO:0033690	positive regulation of osteoblast proliferation
0.55	GO:0036120	cellular response to platelet-derived growth factor stimulus
0.54	GO:0043277	apoptotic cell clearance
0.54	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading

0.65	GO:0004872	receptor activity
0.54	GO:0005178	integrin binding
0.53	GO:0005080	protein kinase C binding
0.41	GO:0042802	identical protein binding
0.41	GO:0038132	neuregulin binding
0.41	GO:0043184	vascular endothelial growth factor receptor 2 binding
0.41	GO:0019960	C-X3-C chemokine binding
0.41	GO:0031994	insulin-like growth factor I binding
0.40	GO:0001968	fibronectin binding
0.40	GO:0017134	fibroblast growth factor binding

0.81	GO:0008305	integrin complex
0.58	GO:0035866	alphav-beta3 integrin-PKCalpha complex
0.57	GO:0071133	alpha9-beta1 integrin-ADAM8 complex
0.53	GO:0009897	external side of plasma membrane
0.51	GO:0016324	apical plasma membrane
0.41	GO:0035868	alphav-beta3 integrin-HMGB1 complex
0.41	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex
0.40	GO:0031258	lamellipodium membrane
0.40	GO:0031528	microvillus membrane
0.40	GO:0031527	filopodium membrane

0.39

EC:5.3.4.1

GO:0003756

sp|Q92072|DNMT1_CHICK
DNA (cytosine-5)-methyltransferase 1
Search

DNMT1

0.74	DNA methyltransferase 1

0.76	GO:0090116	C-5 methylation of cytosine
0.54	GO:0090309	positive regulation of methylation-dependent chromatin silencing
0.53	GO:1901538	changes to DNA methylation involved in embryo development
0.52	GO:0010216	maintenance of DNA methylation
0.52	GO:0051573	negative regulation of histone H3-K9 methylation
0.52	GO:0051571	positive regulation of histone H3-K4 methylation
0.50	GO:0035622	intrahepatic bile duct development
0.50	GO:0007265	Ras protein signal transduction
0.50	GO:0071230	cellular response to amino acid stimulus
0.49	GO:0044030	regulation of DNA methylation

0.77	GO:0003886	DNA (cytosine-5-)-methyltransferase activity
0.76	GO:0003682	chromatin binding
0.62	GO:0008270	zinc ion binding
0.54	GO:0003677	DNA binding
0.41	GO:0003723	RNA binding
0.38	GO:1901265	nucleoside phosphate binding
0.38	GO:0036094	small molecule binding
0.35	GO:0038036	sphingosine-1-phosphate receptor activity
0.35	GO:0030331	estrogen receptor binding
0.35	GO:0042826	histone deacetylase binding

0.59	GO:0005634	nucleus
0.50	GO:0005721	pericentric heterochromatin
0.46	GO:0005657	replication fork
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0043025	neuronal cell body
0.33	GO:0043234	protein complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.77

EC:2.1.1.37

GO:0003886

tr|Q92074|Q92074_CHICK
Beta-1,4-galactosyltransferase
Search

B4GALT1

0.88	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 1

0.60	GO:0005975	carbohydrate metabolic process
0.46	GO:0060058	positive regulation of apoptotic process involved in mammary gland involution
0.46	GO:0007341	penetration of zona pellucida
0.46	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing
0.46	GO:0045136	development of secondary sexual characteristics
0.45	GO:0060046	regulation of acrosome reaction
0.45	GO:0060055	angiogenesis involved in wound healing
0.45	GO:0007339	binding of sperm to zona pellucida
0.44	GO:0002526	acute inflammatory response
0.44	GO:0048754	branching morphogenesis of an epithelial tube

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.42	GO:0030145	manganese ion binding
0.41	GO:0008092	cytoskeletal protein binding

0.46	GO:0000138	Golgi trans cisterna
0.45	GO:0030057	desmosome
0.45	GO:0031526	brush border membrane
0.44	GO:0016323	basolateral plasma membrane
0.44	GO:0009897	external side of plasma membrane
0.41	GO:0005615	extracellular space
0.34	GO:0005874	microtubule
0.30	GO:0016021	integral component of membrane

0.65

GO:0016757

sp|Q92075|SCNNA_CHICK
Amiloride-sensitive sodium channel subunit alpha
Search

SCNN1A

0.97	Amiloride-sensitive sodium channel subunit alpha

0.76	GO:0035725	sodium ion transmembrane transport
0.58	GO:0055078	sodium ion homeostasis
0.57	GO:0050891	multicellular organismal water homeostasis
0.41	GO:0050909	sensory perception of taste
0.36	GO:0050896	response to stimulus
0.35	GO:0008217	regulation of blood pressure
0.34	GO:0016567	protein ubiquitination
0.33	GO:0016192	vesicle-mediated transport
0.32	GO:0023052	signaling
0.32	GO:0007154	cell communication

0.85	GO:0015280	ligand-gated sodium channel activity
0.56	GO:0050699	WW domain binding
0.34	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0003779	actin binding
0.33	GO:0008270	zinc ion binding

0.57	GO:0060170	ciliary membrane
0.56	GO:0034706	sodium channel complex
0.55	GO:0016324	apical plasma membrane
0.54	GO:0031514	motile cilium
0.53	GO:0070062	extracellular exosome
0.48	GO:0005887	integral component of plasma membrane
0.39	GO:0005737	cytoplasm
0.36	GO:0009897	external side of plasma membrane
0.36	GO:0015629	actin cytoskeleton
0.34	GO:0044430	cytoskeletal part

sp|Q92076|DPOG1_CHICK
DNA polymerase subunit gamma-1 (Fragment)
Search

POLG

0.71	DNA polymerase gamma, catalytic subunit

0.65	GO:0071897	DNA biosynthetic process
0.64	GO:0006260	DNA replication
0.59	GO:0006287	base-excision repair, gap-filling
0.49	GO:0032042	mitochondrial DNA metabolic process
0.41	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.40	GO:0055093	response to hyperoxia
0.40	GO:0007568	aging
0.40	GO:0010332	response to gamma radiation
0.40	GO:0071333	cellular response to glucose stimulus
0.38	GO:0009416	response to light stimulus

0.69	GO:0003887	DNA-directed DNA polymerase activity
0.57	GO:0002020	protease binding
0.54	GO:0003682	chromatin binding
0.54	GO:0003677	DNA binding
0.44	GO:0008408	3'-5' exonuclease activity

0.84	GO:0005760	gamma DNA polymerase complex
0.57	GO:0042645	mitochondrial nucleoid
0.44	GO:0043234	protein complex
0.40	GO:0043195	terminal bouton
0.36	GO:0070062	extracellular exosome
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:2.7.7.7

GO:0003887

sp|Q92080|NARE_CHICK
Erythroblast NAD(P)(+)--arginine ADP-ribosyltransferase
Search

ART1

0.75	Erythroblast NAD(P)(+)--arginine ADP-ribosyltransferase

0.84	GO:0006471	protein ADP-ribosylation
0.36	GO:0019677	NAD catabolic process
0.35	GO:0046677	response to antibiotic
0.34	GO:0006501	C-terminal protein lipidation
0.34	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0018195	peptidyl-arginine modification
0.33	GO:0006525	arginine metabolic process

0.85	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity
0.49	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.36	GO:0061810	NAD glycohydrolase activity
0.34	GO:0004984	olfactory receptor activity

0.49	GO:0031225	anchored component of membrane
0.46	GO:0009986	cell surface
0.38	GO:0033017	sarcoplasmic reticulum membrane
0.37	GO:0044194	cytolytic granule
0.35	GO:0005615	extracellular space
0.34	GO:0031226	intrinsic component of plasma membrane
0.33	GO:0098552	side of membrane
0.30	GO:0016021	integral component of membrane

0.85

EC:2.4.2.31

GO:0003956

sp|Q92108|ANXA1_CHICK
Annexin A1 (Fragment)
Search

0.28

Annexin

0.71	GO:0043086	negative regulation of catalytic activity
0.61	GO:0045629	negative regulation of T-helper 2 cell differentiation
0.61	GO:0045627	positive regulation of T-helper 1 cell differentiation
0.59	GO:0002548	monocyte chemotaxis
0.59	GO:0045920	negative regulation of exocytosis
0.59	GO:0032743	positive regulation of interleukin-2 production
0.59	GO:0014839	myoblast migration involved in skeletal muscle regeneration
0.59	GO:0097350	neutrophil clearance
0.59	GO:0071385	cellular response to glucocorticoid stimulus
0.58	GO:2000483	negative regulation of interleukin-8 secretion

0.85	GO:0004859	phospholipase inhibitor activity
0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.57	GO:0098641	cadherin binding involved in cell-cell adhesion
0.56	GO:0048306	calcium-dependent protein binding
0.53	GO:0030674	protein binding, bridging
0.45	GO:0005198	structural molecule activity
0.41	GO:0033676	double-stranded DNA-dependent ATPase activity
0.40	GO:0036310	annealing helicase activity
0.39	GO:0003727	single-stranded RNA binding

0.61	GO:0031232	extrinsic component of external side of plasma membrane
0.57	GO:0016328	lateral plasma membrane
0.56	GO:0001533	cornified envelope
0.55	GO:0070062	extracellular exosome
0.55	GO:0016324	apical plasma membrane
0.54	GO:0005913	cell-cell adherens junction
0.54	GO:0042383	sarcolemma
0.54	GO:0005884	actin filament
0.54	GO:0031514	motile cilium
0.53	GO:0005768	endosome

sp|Q92172|TEF_CHICK
Transcription factor VBP
Search

TEF

0.97	Thyrotrophic embryonic factor

0.69	GO:0006357	regulation of transcription by RNA polymerase II
0.51	GO:0045893	positive regulation of transcription, DNA-templated
0.44	GO:0006366	transcription by RNA polymerase II
0.43	GO:0007275	multicellular organism development
0.41	GO:0071482	cellular response to light stimulus
0.38	GO:0048511	rhythmic process

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0003690	double-stranded DNA binding
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.34	GO:0005515	protein binding

0.61

GO:0005634

nucleus

sp|Q92177|CAN3_CHICK
Calpain-3
Search

CAPN3

0.93	Calpain 3 transcription variant 10

0.85	GO:0045214	sarcomere organization
0.64	GO:0014718	positive regulation of satellite cell activation involved in skeletal muscle regeneration
0.61	GO:0033234	negative regulation of protein sumoylation
0.61	GO:0006508	proteolysis
0.60	GO:0070315	G1 to G0 transition involved in cell differentiation
0.59	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.58	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.58	GO:0071472	cellular response to salt stress
0.58	GO:0071277	cellular response to calcium ion
0.58	GO:2001015	negative regulation of skeletal muscle cell differentiation

0.82	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.69	GO:0005509	calcium ion binding
0.64	GO:0055103	ligase regulator activity
0.62	GO:0031432	titin binding
0.60	GO:0008307	structural constituent of muscle
0.57	GO:0032947	protein complex scaffold activity
0.57	GO:0031402	sodium ion binding
0.34	GO:0005102	receptor binding
0.34	GO:0019899	enzyme binding
0.33	GO:0004871	signal transducer activity

0.53	GO:0030315	T-tubule
0.51	GO:0030018	Z disc
0.50	GO:0005829	cytosol
0.46	GO:0005634	nucleus
0.46	GO:0043234	protein complex

0.33

GO:0004553

sp|Q92178|CAN2_CHICK
Calpain-2 catalytic subunit
Search

CAPN2

0.89	Calpain-2 catalytic subunit

0.73	GO:0051493	regulation of cytoskeleton organization
0.61	GO:0006508	proteolysis
0.54	GO:0071230	cellular response to amino acid stimulus
0.53	GO:0007520	myoblast fusion
0.50	GO:0001824	blastocyst development
0.48	GO:0007586	digestion
0.47	GO:0044257	cellular protein catabolic process
0.38	GO:0001666	response to hypoxia
0.36	GO:0051604	protein maturation
0.36	GO:0043066	negative regulation of apoptotic process

0.82	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.70	GO:0005509	calcium ion binding
0.39	GO:1990782	protein tyrosine kinase binding
0.37	GO:0046982	protein heterodimerization activity
0.36	GO:0008092	cytoskeletal protein binding

0.54	GO:0031143	pseudopodium
0.54	GO:0097038	perinuclear endoplasmic reticulum
0.51	GO:0045121	membrane raft
0.50	GO:0005764	lysosome
0.47	GO:0005794	Golgi apparatus
0.47	GO:0000785	chromatin
0.46	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.41	GO:0030425	dendrite
0.41	GO:0005886	plasma membrane

sp|Q92179|CHST3_CHICK
Carbohydrate sulfotransferase 3
Search

CHST3

0.56	Carbohydrate sulfotransferase 3

0.60	GO:1903510	mucopolysaccharide metabolic process
0.59	GO:0005975	carbohydrate metabolic process
0.58	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process
0.50	GO:0006790	sulfur compound metabolic process
0.50	GO:0006024	glycosaminoglycan biosynthetic process
0.45	GO:0043436	oxoacid metabolic process
0.37	GO:0043029	T cell homeostasis
0.36	GO:0014012	peripheral nervous system axon regeneration
0.35	GO:0051272	positive regulation of cellular component movement
0.34	GO:0006954	inflammatory response

0.78

GO:0008146

sulfotransferase activity

0.72	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

0.78

GO:0008146

sp|Q92182|SIAT1_CHICK
Beta-galactoside alpha-2,6-sialyltransferase 1
Search

ST6GAL1

0.97	LOW QUALITY PROTEIN: beta-galactoside alpha-2,6-sialyltransferase 1

0.83	GO:0097503	sialylation
0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.60	GO:0036211	protein modification process
0.56	GO:0044267	cellular protein metabolic process
0.50	GO:0006054	N-acetylneuraminate metabolic process
0.47	GO:0009311	oligosaccharide metabolic process
0.35	GO:2000110	negative regulation of macrophage apoptotic process
0.34	GO:0050922	negative regulation of chemotaxis
0.34	GO:1900024	regulation of substrate adhesion-dependent cell spreading

0.83	GO:0008373	sialyltransferase activity
0.33	GO:0005515	protein binding

0.63	GO:0005794	Golgi apparatus
0.43	GO:0098588	bounding membrane of organelle
0.42	GO:0031984	organelle subcompartment
0.36	GO:0005576	extracellular region
0.34	GO:0031982	vesicle
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.83

GO:0008373

sp|Q92183|SIA7A_CHICK
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
Search

ST6GALNAC1

0.97	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1

0.83	GO:0097503	sialylation
0.74	GO:0006486	protein glycosylation
0.51	GO:0009311	oligosaccharide metabolic process
0.50	GO:0018196	peptidyl-asparagine modification
0.49	GO:0001574	ganglioside biosynthetic process
0.46	GO:0016051	carbohydrate biosynthetic process
0.33	GO:0016567	protein ubiquitination
0.32	GO:0042981	regulation of apoptotic process
0.31	GO:0007165	signal transduction

0.84	GO:0008373	sialyltransferase activity
0.33	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0016874	ligase activity
0.32	GO:0016887	ATPase activity
0.32	GO:0046872	metal ion binding

0.56	GO:0005794	Golgi apparatus
0.45	GO:0098588	bounding membrane of organelle
0.44	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.84	EC:2.4.99	GO:0008373
0.33	KEGG:R03876	GO:0004842

sp|Q92184|SIA7B_CHICK
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
Search

ST6GALNAC2

0.96	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1

0.83	GO:0097503	sialylation
0.74	GO:0006486	protein glycosylation
0.50	GO:0018196	peptidyl-asparagine modification
0.47	GO:0009311	oligosaccharide metabolic process
0.40	GO:0001574	ganglioside biosynthetic process
0.38	GO:0016051	carbohydrate biosynthetic process
0.33	GO:0016567	protein ubiquitination

0.84	GO:0008373	sialyltransferase activity
0.33	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0016874	ligase activity
0.32	GO:0016887	ATPase activity
0.32	GO:0046872	metal ion binding

0.66	GO:0005794	Golgi apparatus
0.45	GO:0098588	bounding membrane of organelle
0.44	GO:0031984	organelle subcompartment
0.33	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.84	EC:2.4.99	GO:0008373
0.33	KEGG:R03876	GO:0004842

tr|Q95601|Q95601_CHICK
MHC class I alpha chain 2
Search

0.41	MHC class I molecule

0.40	GO:0042605	peptide antigen binding
0.35	GO:0042289	MHC class II protein binding
0.32	GO:0046872	metal ion binding

0.38	GO:0009986	cell surface
0.34	GO:0042611	MHC protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q98892|OBCAM_CHICK
Opioid-binding protein/cell adhesion molecule homolog
Search

OPCML

0.87	Opioid binding protein/cell adhesion molecule like

0.64	GO:0007155	cell adhesion
0.51	GO:0006501	C-terminal protein lipidation
0.50	GO:0008038	neuron recognition
0.44	GO:0032355	response to estradiol
0.44	GO:0021549	cerebellum development
0.44	GO:0010977	negative regulation of neuron projection development

0.42

GO:0005515

protein binding

0.70	GO:0031225	anchored component of membrane
0.51	GO:0005886	plasma membrane
0.49	GO:0005615	extracellular space
0.49	GO:1903561	extracellular vesicle
0.45	GO:0060076	excitatory synapse
0.43	GO:0030424	axon
0.42	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|Q98907|P2RY3_CHICK
P2Y purinoceptor 3
Search

P2RY6

0.97	Pyrimidinergic receptor P2Y, G-protein coupled, 6

0.85	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway
0.71	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.63	GO:0030321	transepithelial chloride transport
0.57	GO:0071380	cellular response to prostaglandin E stimulus
0.57	GO:0090075	relaxation of muscle
0.54	GO:0030168	platelet activation
0.51	GO:0071407	cellular response to organic cyclic compound
0.40	GO:0014911	positive regulation of smooth muscle cell migration
0.38	GO:0043270	positive regulation of ion transport
0.33	GO:0046856	phosphatidylinositol dephosphorylation

0.85	GO:0045028	G-protein coupled purinergic nucleotide receptor activity
0.59	GO:0015065	uridine nucleotide receptor activity
0.36	GO:0019103	pyrimidine nucleotide binding
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0046872	metal ion binding
0.32	GO:0016787	hydrolase activity

0.40	GO:0016323	basolateral plasma membrane
0.40	GO:0016324	apical plasma membrane
0.34	GO:0005887	integral component of plasma membrane

0.32

GO:0016787

sp|Q98910|CD3E_CHICK
T-cell surface glycoprotein CD3 epsilon chain
Search

CD3E

0.97	T-cell surface glycoprotein CD3 epsilon chain

0.68	GO:0007166	cell surface receptor signaling pathway
0.59	GO:0002913	positive regulation of lymphocyte anergy
0.59	GO:0002666	positive regulation of T cell tolerance induction
0.59	GO:0002667	regulation of T cell anergy
0.58	GO:0045086	positive regulation of interleukin-2 biosynthetic process
0.58	GO:0045060	negative thymic T cell selection
0.58	GO:0046641	positive regulation of alpha-beta T cell proliferation
0.57	GO:0032753	positive regulation of interleukin-4 production
0.57	GO:0031295	T cell costimulation
0.57	GO:0045879	negative regulation of smoothened signaling pathway

0.67	GO:0004888	transmembrane signaling receptor activity
0.53	GO:0017124	SH3 domain binding
0.51	GO:0042803	protein homodimerization activity
0.51	GO:0046982	protein heterodimerization activity
0.43	GO:0042608	T cell receptor binding
0.35	GO:0030159	receptor signaling complex scaffold activity
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.34	GO:0019901	protein kinase binding

0.61	GO:0042105	alpha-beta T cell receptor complex
0.56	GO:0001772	immunological synapse
0.56	GO:0043197	dendritic spine
0.54	GO:0009897	external side of plasma membrane
0.53	GO:0044297	cell body
0.51	GO:0005911	cell-cell junction
0.33	GO:0005887	integral component of plasma membrane

sp|Q98913|OLF8_CHICK
Olfactory receptor-like protein COR8 (Fragment)
Search

0.37	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0016573	histone acetylation
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.76	GO:0004984	olfactory receptor activity
0.70	GO:0004930	G-protein coupled receptor activity
0.47	GO:0005549	odorant binding
0.33	GO:0004402	histone acetyltransferase activity
0.32	GO:0003723	RNA binding

0.55	GO:0005886	plasma membrane
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.33

GO:0004402

sp|Q98914|OLF9_CHICK
Olfactory receptor-like protein COR9 (Fragment)
Search

0.40	Olfactory receptor family 5 subfamily D (Fragment)

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.70	GO:0004930	G-protein coupled receptor activity
0.49	GO:0005549	odorant binding

0.54	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q98917|PMEL_CHICK
Melanocyte protein PMEL
Search

0.88	Melanocyte protein PMEL

0.66	GO:0032438	melanosome organization
0.59	GO:0048066	developmental pigmentation
0.37	GO:0048023	positive regulation of melanin biosynthetic process
0.37	GO:0042438	melanin biosynthetic process
0.34	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.32	GO:0016310	phosphorylation
0.32	GO:0006259	DNA metabolic process
0.32	GO:0000160	phosphorelay signal transduction system
0.32	GO:0042886	amide transport
0.32	GO:0006351	transcription, DNA-templated

0.44	GO:0042802	identical protein binding
0.34	GO:0004143	diacylglycerol kinase activity
0.34	GO:0004531	deoxyribonuclease II activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003951	NAD+ kinase activity
0.33	GO:0046872	metal ion binding
0.32	GO:0016887	ATPase activity
0.32	GO:0003677	DNA binding

0.55	GO:0042470	melanosome
0.49	GO:0032585	multivesicular body membrane
0.45	GO:0060205	cytoplasmic vesicle lumen
0.44	GO:0005887	integral component of plasma membrane
0.44	GO:0005789	endoplasmic reticulum membrane
0.43	GO:0005794	Golgi apparatus
0.34	GO:0005576	extracellular region

0.34	EC:2.7.1.107	GO:0004143
0.34	KEGG:R00104	GO:0003951

sp|Q98919|LSAMP_CHICK
Limbic system-associated membrane protein
Search

LSAMP

0.85	Opioid-binding protein/cell adhesion molecule

0.64	GO:0035641	locomotory exploration behavior
0.42	GO:0007155	cell adhesion
0.38	GO:0006501	C-terminal protein lipidation
0.38	GO:0007399	nervous system development
0.36	GO:0007631	feeding behavior
0.36	GO:0031346	positive regulation of cell projection organization
0.35	GO:0010720	positive regulation of cell development
0.35	GO:0051962	positive regulation of nervous system development
0.35	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.35	GO:0030154	cell differentiation

0.35

GO:0005515

protein binding

0.54	GO:0005829	cytosol
0.43	GO:0031225	anchored component of membrane
0.38	GO:0005886	plasma membrane
0.35	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|Q98924|HXA9_CHICK
Homeobox protein Hox-A9 (Fragment)
Search

HOXA9

0.85	Homeobox protein Hox-A9

0.63	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0006351	transcription, DNA-templated
0.54	GO:0045638	negative regulation of myeloid cell differentiation
0.52	GO:0007338	single fertilization
0.51	GO:0007548	sex differentiation
0.51	GO:0007283	spermatogenesis
0.50	GO:0042118	endothelial cell activation

0.65	GO:0043565	sequence-specific DNA binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.44	GO:0019899	enzyme binding
0.35	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.40	GO:0016235	aggresome
0.38	GO:0005737	cytoplasm
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part

sp|Q98925|IRF2_CHICK
Interferon regulatory factor 2
Search

IRF2

0.89	Interferon regulatory factor

0.79	GO:0008283	cell proliferation
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0051607	defense response to virus
0.51	GO:1902680	positive regulation of RNA biosynthetic process
0.35	GO:0060337	type I interferon signaling pathway
0.35	GO:0060333	interferon-gamma-mediated signaling pathway
0.35	GO:0010605	negative regulation of macromolecule metabolic process

0.75	GO:0044212	transcription regulatory region DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.52	GO:1990837	sequence-specific double-stranded DNA binding
0.33	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.55	GO:0005925	focal adhesion
0.49	GO:0005829	cytosol
0.48	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q98930|SORL_CHICK
Sortilin-related receptor (Fragment)
Search

SORL1

0.91	Sortilin-related receptor, L(DLR class) A repeats containing

0.69	GO:0005794	Golgi apparatus
0.30	GO:0044425	membrane part

sp|Q98931|LRP8_CHICK
Low-density lipoprotein receptor-related protein 8
Search

LRP8

0.94	Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor

0.48	GO:0006898	receptor-mediated endocytosis
0.41	GO:0021541	ammon gyrus development
0.40	GO:0021987	cerebral cortex development
0.39	GO:0061003	positive regulation of dendritic spine morphogenesis
0.39	GO:0038026	reelin-mediated signaling pathway
0.39	GO:0022030	telencephalon glial cell migration
0.39	GO:0071397	cellular response to cholesterol
0.39	GO:0032793	positive regulation of CREB transcription factor activity
0.39	GO:0021517	ventral spinal cord development
0.39	GO:0061098	positive regulation of protein tyrosine kinase activity

0.69	GO:0005509	calcium ion binding
0.56	GO:0030229	very-low-density lipoprotein particle receptor activity
0.40	GO:0038025	reelin receptor activity
0.39	GO:0034185	apolipoprotein binding
0.39	GO:0008035	high-density lipoprotein particle binding
0.39	GO:0048306	calcium-dependent protein binding
0.38	GO:0019894	kinesin binding
0.37	GO:0005041	low-density lipoprotein receptor activity

0.54	GO:0005901	caveola
0.51	GO:0043235	receptor complex
0.38	GO:0014069	postsynaptic density
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.37	GO:0030424	axon
0.37	GO:0005875	microtubule associated complex
0.37	GO:0005615	extracellular space
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q98932|RAB5C_CHICK
Ras-related protein Rab-5C
Search

RAB5C

0.85	RAB5C, member RAS oncogene family

0.69	GO:0048227	plasma membrane to endosome transport
0.57	GO:0030100	regulation of endocytosis
0.48	GO:0001702	gastrulation with mouth forming second
0.45	GO:0007032	endosome organization
0.44	GO:0001525	angiogenesis
0.43	GO:0098609	cell-cell adhesion
0.42	GO:0019882	antigen processing and presentation
0.38	GO:0060061	Spemann organizer formation
0.38	GO:0038092	nodal signaling pathway
0.37	GO:0090504	epiboly

0.68	GO:0003924	GTPase activity
0.66	GO:0019003	GDP binding
0.66	GO:0005525	GTP binding
0.46	GO:0030742	GTP-dependent protein binding

0.64	GO:0005768	endosome
0.60	GO:0005811	lipid droplet
0.53	GO:0030139	endocytic vesicle
0.45	GO:0070062	extracellular exosome
0.40	GO:0005886	plasma membrane
0.39	GO:0098993	anchored component of synaptic vesicle membrane
0.38	GO:0043231	intracellular membrane-bounded organelle

tr|Q98934|Q98934_CHICK
Nuclear orphan receptor ROR-beta
Search

RORB

0.94	Nuclear orphan receptor ROR-beta

0.79	GO:0030522	intracellular receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.63	GO:0046548	retinal rod cell development
0.63	GO:0046549	retinal cone cell development
0.61	GO:0045668	negative regulation of osteoblast differentiation
0.59	GO:0042752	regulation of circadian rhythm
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression

0.82	GO:0004879	nuclear receptor activity
0.79	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.58	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0008134	transcription factor binding
0.52	GO:0003690	double-stranded DNA binding

0.61

GO:0005634

nucleus

sp|Q98936|PTPRG_CHICK
Receptor-type tyrosine-protein phosphatase gamma
Search

PTPRG

0.84	Carbonic anhydrase XVI b

0.75

GO:0035335

peptidyl-tyrosine dephosphorylation

0.75

GO:0004725

protein tyrosine phosphatase activity

0.30

GO:0031224

intrinsic component of membrane

0.75

GO:0004725

sp|Q98937|FOXD1_CHICK
Forkhead box protein D1
Search

0.94	Winged helix protein CWH-1

0.57	GO:0006355	regulation of transcription, DNA-templated
0.51	GO:0030154	cell differentiation
0.50	GO:0009653	anatomical structure morphogenesis
0.50	GO:1903508	positive regulation of nucleic acid-templated transcription
0.49	GO:0010628	positive regulation of gene expression
0.48	GO:1902679	negative regulation of RNA biosynthetic process
0.47	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.46	GO:0060485	mesenchyme development
0.46	GO:0010629	negative regulation of gene expression
0.45	GO:0061448	connective tissue development

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003690	double-stranded DNA binding
0.41	GO:0008301	DNA binding, bending
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.42	GO:0000785	chromatin
0.41	GO:0070013	intracellular organelle lumen
0.34	GO:0005667	transcription factor complex

sp|Q98938|IHH_CHICK
Indian hedgehog protein
Search

IHH

0.86	Indian hedgehog

0.74	GO:0007267	cell-cell signaling
0.71	GO:0016539	intein-mediated protein splicing
0.69	GO:0007275	multicellular organism development
0.62	GO:0033084	regulation of immature T cell proliferation in thymus
0.62	GO:0033089	positive regulation of T cell differentiation in thymus
0.61	GO:0046639	negative regulation of alpha-beta T cell differentiation
0.61	GO:0001649	osteoblast differentiation
0.61	GO:0045880	positive regulation of smoothened signaling pathway
0.61	GO:0002053	positive regulation of mesenchymal cell proliferation
0.60	GO:0048074	negative regulation of eye pigmentation

0.63	GO:0005113	patched binding
0.60	GO:0008233	peptidase activity
0.51	GO:0005509	calcium ion binding
0.46	GO:0043237	laminin-1 binding
0.42	GO:0005539	glycosaminoglycan binding
0.39	GO:0008270	zinc ion binding
0.35	GO:0016015	morphogen activity
0.34	GO:0019901	protein kinase binding
0.33	GO:0022857	transmembrane transporter activity

0.65	GO:0005615	extracellular space
0.54	GO:0005578	proteinaceous extracellular matrix
0.52	GO:0005886	plasma membrane
0.43	GO:0098857	membrane microdomain
0.42	GO:0009986	cell surface
0.35	GO:0005634	nucleus
0.34	GO:0008021	synaptic vesicle
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon

0.60

GO:0008233

sp|Q98943|CASP2_CHICK
Caspase-2
Search

CASP2

0.96	Caspase 2, apoptosis-related cysteine peptidase

0.84	GO:0097194	execution phase of apoptosis
0.73	GO:0042981	regulation of apoptotic process
0.60	GO:0006508	proteolysis
0.58	GO:0035234	ectopic germ cell programmed cell death
0.58	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
0.57	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand
0.56	GO:0071260	cellular response to mechanical stimulus
0.54	GO:0043068	positive regulation of programmed cell death
0.51	GO:0009967	positive regulation of signal transduction
0.49	GO:0051604	protein maturation

0.85	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis
0.51	GO:0019904	protein domain specific binding
0.50	GO:0042802	identical protein binding
0.34	GO:0019899	enzyme binding

0.45	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|Q98944|Q98944_CHICK
Leucine zipper transcription factor
Search

CEBPG

0.97	CCAAT/enhancer binding protein gamma

0.60	GO:0043353	enucleate erythrocyte differentiation
0.59	GO:0045078	positive regulation of interferon-gamma biosynthetic process
0.59	GO:0042267	natural killer cell mediated cytotoxicity
0.57	GO:0045739	positive regulation of DNA repair
0.57	GO:0030183	B cell differentiation
0.56	GO:0043433	negative regulation of DNA binding transcription factor activity
0.52	GO:0006366	transcription by RNA polymerase II
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:0016071	mRNA metabolic process
0.40	GO:0001889	liver development

0.58	GO:0003700	DNA binding transcription factor activity
0.54	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0042803	protein homodimerization activity
0.51	GO:0046982	protein heterodimerization activity
0.51	GO:0008134	transcription factor binding
0.39	GO:0044374	sequence-specific DNA binding, bending

0.49	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q98948|SSBP3_CHICK
Single-stranded DNA-binding protein 3
Search

SSBP3

0.88	Single-stranded DNA-binding protein 3

0.55	GO:0021547	midbrain-hindbrain boundary initiation
0.55	GO:0021501	prechordal plate formation
0.55	GO:2000744	positive regulation of anterior head development
0.52	GO:0060323	head morphogenesis
0.51	GO:0002244	hematopoietic progenitor cell differentiation
0.49	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:0008284	positive regulation of cell proliferation
0.45	GO:0006461	protein complex assembly
0.43	GO:0006366	transcription by RNA polymerase II
0.38	GO:0048936	peripheral nervous system neuron axonogenesis

0.67	GO:0003697	single-stranded DNA binding
0.45	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.44	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0005515	protein binding

0.41	GO:0043234	protein complex
0.39	GO:0005634	nucleus
0.33	GO:0005739	mitochondrion

sp|Q98949|TYRO3_CHICK
Tyrosine-protein kinase receptor TYRO3
Search

TYRO3

0.94	Tyrosine-protein kinase receptor TYRO3

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.66	GO:0070050	neuron cellular homeostasis
0.66	GO:0060068	vagina development
0.66	GO:0001779	natural killer cell differentiation
0.66	GO:0034122	negative regulation of toll-like receptor signaling pathway
0.66	GO:0070527	platelet aggregation
0.66	GO:0043491	protein kinase B signaling
0.66	GO:0043277	apoptotic cell clearance
0.65	GO:0034446	substrate adhesion-dependent cell spreading
0.65	GO:0021885	forebrain cell migration

0.77	GO:0004713	protein tyrosine kinase activity
0.67	GO:0043548	phosphatidylinositol 3-kinase binding
0.56	GO:0046982	protein heterodimerization activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0019199	transmembrane receptor protein kinase activity
0.37	GO:0001618	virus receptor activity
0.36	GO:0005057	signal transducer activity, downstream of receptor

0.49	GO:0005635	nuclear envelope
0.47	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.77

GO:0004713

tr|Q98950|Q98950_CHICK
CVg1 protein
Search

GDF3

0.97	Growth differentiation factor 3

0.76	GO:0010469	regulation of receptor activity
0.56	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.51	GO:0048598	embryonic morphogenesis
0.51	GO:0060395	SMAD protein signal transduction
0.51	GO:0007389	pattern specification process
0.50	GO:0006357	regulation of transcription by RNA polymerase II
0.50	GO:0048568	embryonic organ development
0.50	GO:0045605	negative regulation of epidermal cell differentiation
0.50	GO:0009888	tissue development
0.49	GO:0048468	cell development

0.78	GO:0008083	growth factor activity
0.51	GO:0005160	transforming growth factor beta receptor binding
0.49	GO:0005125	cytokine activity
0.46	GO:0019901	protein kinase binding
0.38	GO:0016015	morphogen activity
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0019838	growth factor binding
0.35	GO:0046982	protein heterodimerization activity
0.33	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
0.33	GO:0008270	zinc ion binding

0.66	GO:0005576	extracellular region
0.37	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.33

EC:3.5.4

GO:0016814

sp|Q98953|S10A6_CHICK
Protein S100-A6
Search

0.10	S100 calcium binding protein A6

0.51	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.37	GO:0043542	endothelial cell migration
0.33	GO:0034220	ion transmembrane transport

0.69	GO:0005509	calcium ion binding
0.57	GO:0042802	identical protein binding
0.56	GO:0044548	S100 protein binding
0.56	GO:0048306	calcium-dependent protein binding
0.56	GO:0005523	tropomyosin binding
0.54	GO:0050786	RAGE receptor binding
0.52	GO:0046914	transition metal ion binding
0.48	GO:0046983	protein dimerization activity
0.38	GO:0019899	enzyme binding
0.34	GO:0003779	actin binding

0.60	GO:0048471	perinuclear region of cytoplasm
0.54	GO:0001726	ruffle
0.53	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.52	GO:0005576	extracellular region
0.51	GO:0005635	nuclear envelope
0.49	GO:0005829	cytosol
0.34	GO:0043005	neuron projection

sp|Q98SH2|AT2B1_CHICK
Plasma membrane calcium-transporting ATPase 1 (Fragment)
Search

ATP2B1

0.78	Plasma membrane calcium-transporting ATPase 1

0.77	GO:0070588	calcium ion transmembrane transport
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.56	GO:1901660	calcium ion export
0.53	GO:0006874	cellular calcium ion homeostasis
0.42	GO:0007399	nervous system development
0.41	GO:0071386	cellular response to corticosterone stimulus
0.40	GO:0007605	sensory perception of sound
0.40	GO:0007423	sensory organ development
0.40	GO:0071305	cellular response to vitamin D
0.39	GO:0009409	response to cold

0.81	GO:0005388	calcium-transporting ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0030165	PDZ domain binding
0.40	GO:0005516	calmodulin binding
0.35	GO:0046872	metal ion binding

0.43	GO:0005634	nucleus
0.42	GO:0005887	integral component of plasma membrane
0.41	GO:0032591	dendritic spine membrane
0.40	GO:0032809	neuronal cell body membrane
0.39	GO:0016323	basolateral plasma membrane
0.39	GO:0016324	apical plasma membrane
0.39	GO:0045121	membrane raft
0.38	GO:0009898	cytoplasmic side of plasma membrane
0.35	GO:0070062	extracellular exosome
0.35	GO:0030054	cell junction

0.81

EC:3.6.3.8

GO:0005388

sp|Q98SH3|ADRM1_CHICK
Proteasomal ubiquitin receptor ADRM1
Search

ADRM1

0.90	Adhesion regulating molecule 1

0.55	GO:0010950	positive regulation of endopeptidase activity
0.53	GO:0043248	proteasome assembly
0.51	GO:0006368	transcription elongation from RNA polymerase II promoter
0.43	GO:0006511	ubiquitin-dependent protein catabolic process
0.38	GO:0060399	positive regulation of growth hormone receptor signaling pathway
0.37	GO:0060009	Sertoli cell development
0.37	GO:0072520	seminiferous tubule development
0.37	GO:0033081	regulation of T cell differentiation in thymus
0.37	GO:0042699	follicle-stimulating hormone signaling pathway
0.37	GO:0060612	adipose tissue development

0.58	GO:0061133	endopeptidase activator activity
0.55	GO:0070628	proteasome binding
0.53	GO:0002020	protease binding
0.45	GO:0043130	ubiquitin binding

0.61	GO:0005634	nucleus
0.51	GO:1905369	endopeptidase complex
0.49	GO:0005737	cytoplasm
0.46	GO:0043233	organelle lumen
0.44	GO:0043234	protein complex
0.42	GO:0044446	intracellular organelle part
0.41	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q98SN3|Q98SN3_CHICK
Aryl hydrocarbon receptor nuclear translocator
Search

ARNT

0.85	Aryl hydrocarbon receptor nuclear translocator

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0033235	positive regulation of protein sumoylation
0.57	GO:0046886	positive regulation of hormone biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0010575	positive regulation of vascular endothelial growth factor production
0.54	GO:1902680	positive regulation of RNA biosynthetic process
0.54	GO:0001666	response to hypoxia
0.52	GO:0030522	intracellular receptor signaling pathway

0.68	GO:0046983	protein dimerization activity
0.64	GO:0017162	aryl hydrocarbon receptor binding
0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0004874	aryl hydrocarbon receptor activity
0.55	GO:0044212	transcription regulatory region DNA binding
0.52	GO:0003713	transcription coactivator activity
0.49	GO:0043565	sequence-specific DNA binding
0.46	GO:0003690	double-stranded DNA binding
0.37	GO:0070491	repressing transcription factor binding
0.37	GO:0008234	cysteine-type peptidase activity

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.53	GO:0034751	aryl hydrocarbon receptor complex
0.49	GO:0005737	cytoplasm
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.37

GO:0008234

sp|Q98SN7|WNT2B_CHICK
Protein Wnt-2b
Search

tr|Q98SR2|Q98SR2_CHICK
Claudin
Search

CLDN3

0.69

Claudin c

0.56	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.52	GO:0070830	bicellular tight junction assembly
0.52	GO:0003382	epithelial cell morphogenesis
0.52	GO:0051291	protein heterooligomerization
0.51	GO:0001666	response to hypoxia
0.50	GO:0070293	renal absorption
0.49	GO:0061436	establishment of skin barrier
0.49	GO:0051260	protein homooligomerization
0.46	GO:1902476	chloride transmembrane transport
0.40	GO:0045471	response to ethanol

0.62	GO:0005198	structural molecule activity
0.48	GO:0042802	identical protein binding
0.46	GO:0005254	chloride channel activity
0.35	GO:0001618	virus receptor activity
0.35	GO:0004888	transmembrane signaling receptor activity

0.81	GO:0005923	bicellular tight junction
0.59	GO:0016327	apicolateral plasma membrane
0.54	GO:0016328	lateral plasma membrane
0.42	GO:0005887	integral component of plasma membrane
0.38	GO:0045178	basal part of cell
0.37	GO:0045177	apical part of cell
0.37	GO:0034707	chloride channel complex
0.36	GO:0070062	extracellular exosome
0.36	GO:0016323	basolateral plasma membrane
0.36	GO:0097574	lateral part of cell

tr|Q98SS5|Q98SS5_CHICK
Doublecortin
Search

DCX

0.97	Neuronal migration protein doublecortin

0.63	GO:0035556	intracellular signal transduction
0.58	GO:0021860	pyramidal neuron development
0.56	GO:0021819	layer formation in cerebral cortex
0.56	GO:0021766	hippocampus development
0.55	GO:0021952	central nervous system projection neuron axonogenesis
0.54	GO:0048675	axon extension
0.54	GO:0001764	neuron migration
0.54	GO:0048813	dendrite morphogenesis
0.43	GO:0006468	protein phosphorylation
0.40	GO:0018209	peptidyl-serine modification

0.43	GO:0004672	protein kinase activity
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0019901	protein kinase binding
0.36	GO:0008017	microtubule binding
0.36	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.34	GO:0005516	calmodulin binding
0.32	GO:0003677	DNA binding

0.51	GO:0043005	neuron projection
0.48	GO:0005829	cytosol
0.39	GO:0015630	microtubule cytoskeleton
0.39	GO:0099513	polymeric cytoskeletal fiber
0.34	GO:0043025	neuronal cell body
0.34	GO:0030427	site of polarized growth
0.34	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0005634	nucleus
0.33	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q98ST5|CRLD1_CHICK
Cysteine-rich secretory protein LCCL domain-containing 1
Search

CRISPLD1

0.93	Cysteine-rich secretory protein LCCL domain-containing 1

0.53	GO:0060325	face morphogenesis
0.35	GO:0030198	extracellular matrix organization

0.35

GO:0008201

heparin binding

0.66	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.34	GO:0012505	endomembrane system
0.33	GO:0044444	cytoplasmic part
0.32	GO:0043229	intracellular organelle
0.30	GO:0044425	membrane part

sp|Q98ST6|PI15_CHICK
Peptidase inhibitor 15
Search

PI15

0.97	Peptidase inhibitor 15-A

0.39	GO:0048856	anatomical structure development
0.38	GO:0010466	negative regulation of peptidase activity
0.38	GO:0032501	multicellular organismal process
0.37	GO:0030198	extracellular matrix organization
0.33	GO:0043401	steroid hormone mediated signaling pathway
0.33	GO:0006508	proteolysis
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:0006355	regulation of transcription, DNA-templated

0.38	GO:0030414	peptidase inhibitor activity
0.37	GO:0008201	heparin binding
0.33	GO:0008233	peptidase activity
0.32	GO:0043565	sequence-specific DNA binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0003700	DNA binding transcription factor activity

0.63	GO:0005576	extracellular region
0.38	GO:0031982	vesicle
0.34	GO:0012505	endomembrane system
0.33	GO:0043229	intracellular organelle
0.33	GO:0044444	cytoplasmic part
0.30	GO:0016020	membrane

0.33

GO:0008233

sp|Q98ST7|MOXD1_CHICK
DBH-like monooxygenase protein 1
Search

MOXD1

0.96	Monooxygenase DBH like 1

0.53	GO:0006589	octopamine biosynthetic process
0.53	GO:0042420	dopamine catabolic process
0.53	GO:0042421	norepinephrine biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.34	GO:0006886	intracellular protein transport
0.34	GO:0061025	membrane fusion
0.34	GO:0016192	vesicle-mediated transport

0.84	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.71	GO:0005507	copper ion binding
0.35	GO:0005484	SNAP receptor activity

0.52	GO:0005789	endoplasmic reticulum membrane
0.51	GO:0030667	secretory granule membrane
0.46	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.84

EC:1.14.17

GO:0016715

tr|Q98SU9|Q98SU9_CHICK
Survival motor neuron protein
Search

0.89	Survival motor neuron

0.69	GO:0006397	mRNA processing
0.48	GO:0010975	regulation of neuron projection development
0.47	GO:0007409	axonogenesis
0.46	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
0.46	GO:1903862	positive regulation of oxidative phosphorylation
0.45	GO:0048934	peripheral nervous system neuron differentiation
0.45	GO:1904396	regulation of neuromuscular junction development
0.44	GO:1990138	neuron projection extension
0.44	GO:0007528	neuromuscular junction development
0.44	GO:0061387	regulation of extent of cell growth

0.59	GO:0003723	RNA binding
0.37	GO:0042802	identical protein binding
0.36	GO:0017134	fibroblast growth factor binding

0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.46	GO:0032797	SMN complex
0.45	GO:0043204	perikaryon
0.43	GO:0035770	ribonucleoprotein granule
0.42	GO:0043005	neuron projection
0.42	GO:0120114	Sm-like protein family complex
0.42	GO:0099512	supramolecular fiber
0.41	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part

sp|Q98T89|TWSG1_CHICK
Twisted gastrulation protein homolog 1
Search

TWSG1

0.97	Twisted gastrulation BMP signaling modulator 1

0.85	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation
0.79	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.78	GO:0045668	negative regulation of osteoblast differentiation
0.78	GO:0030513	positive regulation of BMP signaling pathway
0.76	GO:0007435	salivary gland morphogenesis
0.76	GO:0001707	mesoderm formation
0.76	GO:0030514	negative regulation of BMP signaling pathway
0.76	GO:0001818	negative regulation of cytokine production
0.76	GO:0007179	transforming growth factor beta receptor signaling pathway
0.75	GO:0030509	BMP signaling pathway

0.81

GO:0050431

transforming growth factor beta binding

0.66	GO:0005615	extracellular space
0.41	GO:1903561	extracellular vesicle
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

sp|Q98TA4|MBL_CHICK
Mannose-binding protein
Search

0.78	Pulmonary surfactant-associated protein A

0.78	GO:0001867	complement activation, lectin pathway
0.42	GO:0006958	complement activation, classical pathway
0.41	GO:0044130	negative regulation of growth of symbiont in host
0.41	GO:0009617	response to bacterium
0.40	GO:0051851	modification by host of symbiont morphology or physiology
0.40	GO:0050766	positive regulation of phagocytosis
0.40	GO:0098542	defense response to other organism
0.38	GO:0048525	negative regulation of viral process
0.38	GO:0008228	opsonization
0.38	GO:0051883	killing of cells in other organism involved in symbiotic interaction

0.76	GO:0005537	mannose binding
0.45	GO:0005201	extracellular matrix structural constituent
0.40	GO:0048306	calcium-dependent protein binding
0.38	GO:0005509	calcium ion binding
0.37	GO:0048407	platelet-derived growth factor binding
0.37	GO:0005102	receptor binding
0.36	GO:0042802	identical protein binding
0.35	GO:0002020	protease binding
0.35	GO:0070273	phosphatidylinositol-4-phosphate binding
0.34	GO:0030247	polysaccharide binding

0.70	GO:0005581	collagen trimer
0.48	GO:0005576	extracellular region
0.36	GO:0031410	cytoplasmic vesicle
0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0099081	supramolecular polymer
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.33	GO:0016328	lateral plasma membrane
0.33	GO:0016324	apical plasma membrane
0.33	GO:0005923	bicellular tight junction

0.32

GO:0004553

sp|Q98TF5|RL39_CHICK
60S ribosomal protein L39
Search

RPL39

0.83	Angiomotin like 2

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.41	GO:0007283	spermatogenesis
0.38	GO:0002227	innate immune response in mucosa
0.37	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.37	GO:0019731	antibacterial humoral response
0.37	GO:0050830	defense response to Gram-positive bacterium
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

0.64	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.45	GO:0044445	cytosolic part
0.40	GO:0044446	intracellular organelle part
0.36	GO:0005615	extracellular space
0.34	GO:0005844	polysome

sp|Q98TF6|RL36_CHICK
60S ribosomal protein L36
Search

RPL36

0.70	60S ribosomal protein L36 pseudogene

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.43	GO:0007420	brain development
0.41	GO:0051726	regulation of cell cycle
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process

0.63	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.34	GO:0070840	dynein complex binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0008134	transcription factor binding
0.32	GO:0016491	oxidoreductase activity

0.60	GO:0005840	ribosome
0.48	GO:0044445	cytosolic part
0.46	GO:0005844	polysome
0.43	GO:0005730	nucleolus
0.30	GO:0016020	membrane

0.32

GO:0016491

sp|Q98TF7|RL35_CHICK
60S ribosomal protein L35
Search

RPL35

0.76	Ribosomal protein L35

0.59	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.47	GO:0042273	ribosomal large subunit biogenesis
0.44	GO:0016072	rRNA metabolic process
0.41	GO:0030218	erythrocyte differentiation
0.40	GO:0043009	chordate embryonic development
0.39	GO:0051726	regulation of cell cycle
0.35	GO:0071493	cellular response to UV-B

0.62	GO:0003735	structural constituent of ribosome
0.47	GO:0003729	mRNA binding
0.34	GO:0043021	ribonucleoprotein complex binding
0.33	GO:0044212	transcription regulatory region DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005840	ribosome
0.46	GO:0044445	cytosolic part
0.40	GO:0044446	intracellular organelle part
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0005634	nucleus
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q98TF8|RL22_CHICK
60S ribosomal protein L22
Search

RPL22

0.59	Chromodomain helicase DNA binding protein 5

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.47	GO:0030217	T cell differentiation
0.44	GO:0046631	alpha-beta T cell activation
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.45	GO:0008201	heparin binding
0.41	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.43	GO:0044445	cytosolic part
0.39	GO:0044446	intracellular organelle part
0.38	GO:0005634	nucleus
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0098562	cytoplasmic side of membrane

tr|Q98TH5|Q98TH5_CHICK
Ribosomal protein S11
Search

RPS11

0.60	Ribosomal protein S11

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0010469	regulation of receptor activity
0.35	GO:0001649	osteoblast differentiation
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.37	GO:0019843	rRNA binding
0.36	GO:0005125	cytokine activity
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.61	GO:0005840	ribosome
0.50	GO:0044445	cytosolic part
0.44	GO:0044446	intracellular organelle part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:1.2.1

GO:0016620

tr|Q98TQ8|Q98TQ8_CHICK
Connective tissue growth factor
Search

CTGF

0.95	Connective tissue growth factor XCTGF

0.73	GO:0001558	regulation of cell growth
0.58	GO:0035988	chondrocyte proliferation
0.58	GO:0001502	cartilage condensation
0.57	GO:0051496	positive regulation of stress fiber assembly
0.56	GO:0032330	regulation of chondrocyte differentiation
0.55	GO:0046330	positive regulation of JNK cascade
0.55	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.55	GO:0030324	lung development
0.55	GO:0008543	fibroblast growth factor receptor signaling pathway
0.55	GO:0001894	tissue homeostasis

0.77	GO:0005520	insulin-like growth factor binding
0.57	GO:0005178	integrin binding
0.56	GO:0008201	heparin binding
0.55	GO:0008022	protein C-terminus binding
0.39	GO:0001968	fibronectin binding
0.37	GO:0008083	growth factor activity

0.63	GO:0005576	extracellular region
0.38	GO:0005801	cis-Golgi network
0.37	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005938	cell cortex
0.36	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane

sp|Q98TX3|PDCD4_CHICK
Programmed cell death protein 4
Search

PDCD4

0.96	Programmed Cell death 4 (Neoplastic transformation inhibitor)

0.84	GO:1904761	negative regulation of myofibroblast differentiation
0.84	GO:1905064	negative regulation of vascular smooth muscle cell differentiation
0.83	GO:1905461	positive regulation of vascular associated smooth muscle cell apoptotic process
0.81	GO:1900016	negative regulation of cytokine production involved in inflammatory response
0.81	GO:2000353	positive regulation of endothelial cell apoptotic process
0.80	GO:1904706	negative regulation of vascular smooth muscle cell proliferation
0.77	GO:1901224	positive regulation of NIK/NF-kappaB signaling
0.76	GO:0030509	BMP signaling pathway
0.75	GO:0050729	positive regulation of inflammatory response
0.75	GO:0007569	cell aging

0.40	GO:0003723	RNA binding
0.37	GO:0005515	protein binding
0.30	GO:0003824	catalytic activity

0.63	GO:0005829	cytosol
0.57	GO:0005634	nucleus

tr|Q98TX7|Q98TX7_CHICK
Interferon regulatory factor 4
Search

IRF4

0.86	Interferon regulatory factor

0.61	GO:0045368	positive regulation of interleukin-13 biosynthetic process
0.61	GO:0045404	positive regulation of interleukin-4 biosynthetic process
0.60	GO:0045082	positive regulation of interleukin-10 biosynthetic process
0.58	GO:0045086	positive regulation of interleukin-2 biosynthetic process
0.57	GO:0072540	T-helper 17 cell lineage commitment
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:0006355	regulation of transcription, DNA-templated
0.56	GO:0043011	myeloid dendritic cell differentiation
0.56	GO:0042832	defense response to protozoan
0.56	GO:0034122	negative regulation of toll-like receptor signaling pathway

0.75	GO:0044212	transcription regulatory region DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.52	GO:0016279	protein-lysine N-methyltransferase activity
0.51	GO:1990837	sequence-specific double-stranded DNA binding
0.34	GO:0005515	protein binding
0.32	GO:0003735	structural constituent of ribosome

0.60	GO:0005634	nucleus
0.50	GO:0000785	chromatin
0.50	GO:0044815	DNA packaging complex
0.48	GO:0032993	protein-DNA complex
0.47	GO:0070013	intracellular organelle lumen
0.34	GO:0005829	cytosol
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.52

GO:0016279

tr|Q98UC3|Q98UC3_CHICK
Ubiquitin fusion-degradation 1-like protein
Search

UFD1

0.83	Ubiquitin recognition factor in ER-associated degradation protein 1

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.54	GO:0039536	negative regulation of RIG-I signaling pathway
0.53	GO:0032480	negative regulation of type I interferon production
0.53	GO:0071712	ER-associated misfolded protein catabolic process
0.53	GO:1903513	endoplasmic reticulum to cytosol transport
0.53	GO:0032527	protein exit from endoplasmic reticulum
0.42	GO:0071466	cellular response to xenobiotic stimulus
0.35	GO:0070987	error-free translesion synthesis
0.34	GO:0001501	skeletal system development
0.34	GO:0016579	protein deubiquitination

0.54	GO:0036435	K48-linked polyubiquitin modification-dependent protein binding
0.39	GO:0051117	ATPase binding
0.37	GO:0032403	protein complex binding
0.37	GO:0005102	receptor binding
0.34	GO:0004843	thiol-dependent ubiquitin-specific protease activity

0.56	GO:0036501	UFD1-NPL4 complex
0.54	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex
0.36	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q98UI9|MUC5B_CHICK
Mucin-5B
Search

0.50	GO:0030299	intestinal cholesterol absorption
0.49	GO:0002281	macrophage activation involved in immune response
0.47	GO:0042632	cholesterol homeostasis

0.50	GO:0046790	virion binding
0.40	GO:0005515	protein binding

0.66	GO:0005576	extracellular region
0.38	GO:0043231	intracellular membrane-bounded organelle

tr|Q9DD46|Q9DD46_CHICK
Aldehyde dehydrogenase
Search

ALDH1A3

0.40	Aldehyde dehydrogenase

0.60	GO:0021768	nucleus accumbens development
0.60	GO:0060166	olfactory pit development
0.59	GO:0070384	Harderian gland development
0.59	GO:0002072	optic cup morphogenesis involved in camera-type eye development
0.58	GO:0060013	righting reflex
0.58	GO:0002138	retinoic acid biosynthetic process
0.58	GO:0042574	retinal metabolic process
0.56	GO:0060324	face development
0.56	GO:0050885	neuromuscular process controlling balance
0.56	GO:0051289	protein homotetramerization

0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.58	GO:0070324	thyroid hormone binding
0.52	GO:0070403	NAD+ binding
0.51	GO:0042803	protein homodimerization activity
0.35	GO:0005497	androgen binding
0.34	GO:0005096	GTPase activator activity
0.33	GO:0016301	kinase activity

0.52	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.42	GO:0005886	plasma membrane
0.38	GO:0070062	extracellular exosome

0.69

EC:1.2.1

GO:0016620

sp|Q9DD78|TLR21_CHICK
Toll-like receptor 2 type-1
Search

TLR2

0.79	Toll like receptor 2

0.86	GO:0034134	toll-like receptor 2 signaling pathway
0.84	GO:0050729	positive regulation of inflammatory response
0.84	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
0.82	GO:0050707	regulation of cytokine secretion
0.82	GO:0002237	response to molecule of bacterial origin
0.80	GO:0006954	inflammatory response
0.79	GO:0045087	innate immune response
0.49	GO:0002374	cytokine secretion involved in immune response
0.49	GO:0032613	interleukin-10 production
0.48	GO:0016045	detection of bacterium

0.50	GO:0042497	triacyl lipopeptide binding
0.48	GO:0035325	Toll-like receptor binding
0.47	GO:0038187	pattern recognition receptor activity
0.46	GO:0001530	lipopolysaccharide binding
0.44	GO:0042834	peptidoglycan binding
0.44	GO:0032403	protein complex binding
0.43	GO:0046982	protein heterodimerization activity
0.41	GO:0038023	signaling receptor activity
0.35	GO:0042498	diacyl lipopeptide binding
0.35	GO:0070891	lipoteichoic acid binding

0.49	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex
0.47	GO:0098857	membrane microdomain
0.44	GO:0009986	cell surface
0.44	GO:0005794	Golgi apparatus
0.43	GO:0031226	intrinsic component of plasma membrane
0.42	GO:0030670	phagocytic vesicle membrane
0.37	GO:0044297	cell body
0.36	GO:0106003	amyloid-beta complex
0.35	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex
0.35	GO:0042995	cell projection

sp|Q9DDD0|NRX1A_CHICK
Neurexin-1 (Fragment)
Search

NRXN1

0.90	Neurexin-1-alpha

0.50	GO:0098596	imitative learning
0.49	GO:0098598	learned vocalization behavior or vocal learning
0.49	GO:0031223	auditory behavior
0.49	GO:0071625	vocalization behavior
0.48	GO:0035176	social behavior
0.47	GO:0030534	adult behavior
0.46	GO:0097116	gephyrin clustering involved in postsynaptic density assembly
0.46	GO:0099560	synaptic membrane adhesion
0.46	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly
0.46	GO:2000821	regulation of grooming behavior

0.47	GO:0097109	neuroligin family protein binding
0.45	GO:0033130	acetylcholine receptor binding
0.44	GO:0005246	calcium channel regulator activity
0.43	GO:0050839	cell adhesion molecule binding
0.38	GO:0005105	type 1 fibroblast growth factor receptor binding
0.35	GO:0005509	calcium ion binding
0.35	GO:0048306	calcium-dependent protein binding
0.34	GO:0004888	transmembrane signaling receptor activity

0.46	GO:0005730	nucleolus
0.45	GO:0042734	presynaptic membrane
0.44	GO:0009986	cell surface
0.43	GO:0043025	neuronal cell body
0.43	GO:0031965	nuclear membrane
0.41	GO:0031982	vesicle
0.40	GO:0005783	endoplasmic reticulum
0.38	GO:0043234	protein complex
0.37	GO:0030054	cell junction
0.35	GO:0044295	axonal growth cone

sp|Q9DDD1|GP149_CHICK
Probable G-protein coupled receptor 149
Search

GPR149

0.89	G protein-coupled receptor 149

0.62	GO:0060280	negative regulation of ovulation
0.61	GO:0001547	antral ovarian follicle growth
0.59	GO:0048162	multi-layer follicle stage
0.49	GO:0007186	G-protein coupled receptor signaling pathway
0.46	GO:0007268	chemical synaptic transmission

0.50	GO:0042923	neuropeptide binding
0.49	GO:0004930	G-protein coupled receptor activity

0.46	GO:0043005	neuron projection
0.43	GO:0005887	integral component of plasma membrane

tr|Q9DDD4|Q9DDD4_CHICK
Tetranectin
Search

CLEC3B

0.97	Tetranectin

0.76	GO:0030282	bone mineralization
0.72	GO:0071560	cellular response to transforming growth factor beta stimulus
0.60	GO:0010756	positive regulation of plasminogen activation
0.40	GO:0001501	skeletal system development
0.38	GO:0002576	platelet degranulation

0.83	GO:0036143	kringle domain binding
0.72	GO:0008201	heparin binding
0.62	GO:0005509	calcium ion binding
0.57	GO:0030246	carbohydrate binding

0.79	GO:0001652	granular component
0.65	GO:0005615	extracellular space
0.45	GO:0005737	cytoplasm
0.40	GO:0031012	extracellular matrix
0.40	GO:1903561	extracellular vesicle
0.38	GO:0031983	vesicle lumen
0.36	GO:0097708	intracellular vesicle
0.35	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

sp|Q9DDD5|NBEA_CHICK
Neurobeachin (Fragment)
Search

NBEA

0.53	Neurobeachin

0.58	GO:0008104	protein localization
0.53	GO:0007416	synapse assembly
0.52	GO:0016358	dendrite development
0.42	GO:0006892	post-Golgi vesicle-mediated transport
0.39	GO:0046907	intracellular transport
0.39	GO:0070727	cellular macromolecule localization
0.38	GO:0015833	peptide transport
0.36	GO:0055085	transmembrane transport

0.69	GO:0019901	protein kinase binding
0.42	GO:0051018	protein kinase A binding

0.70	GO:0005802	trans-Golgi network
0.61	GO:0005829	cytosol
0.50	GO:0005886	plasma membrane
0.41	GO:0098794	postsynapse
0.40	GO:0030054	cell junction
0.30	GO:0031224	intrinsic component of membrane

sp|Q9DDN6|NPY2R_CHICK
Neuropeptide Y receptor type 2
Search

NPY2R

0.96	Neuropeptide Y receptor type 2

0.80	GO:0007218	neuropeptide signaling pathway
0.57	GO:0003214	cardiac left ventricle morphogenesis
0.55	GO:0003151	outflow tract morphogenesis
0.52	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.45	GO:0007631	feeding behavior
0.43	GO:0007268	chemical synaptic transmission
0.39	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep
0.39	GO:0033603	positive regulation of dopamine secretion
0.39	GO:2000252	negative regulation of feeding behavior
0.39	GO:0051967	negative regulation of synaptic transmission, glutamatergic

0.84	GO:0004983	neuropeptide Y receptor activity
0.45	GO:0042923	neuropeptide binding
0.35	GO:0005246	calcium channel regulator activity
0.33	GO:0005515	protein binding

0.51	GO:0097730	non-motile cilium
0.36	GO:0005886	plasma membrane
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q9DDT2|BCAP_CHICK
Phosphoinositide 3-kinase adapter protein 1
Search

PIK3AP1

0.93	Phosphoinositide 3-kinase adapter protein 1

0.57	GO:0016310	phosphorylation
0.47	GO:0034162	toll-like receptor 9 signaling pathway
0.47	GO:0034154	toll-like receptor 7 signaling pathway
0.47	GO:0034134	toll-like receptor 2 signaling pathway
0.46	GO:0034142	toll-like receptor 4 signaling pathway
0.46	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.45	GO:0050727	regulation of inflammatory response
0.38	GO:0042325	regulation of phosphorylation
0.38	GO:0032869	cellular response to insulin stimulus
0.38	GO:0031929	TOR signaling

0.60	GO:0016301	kinase activity
0.48	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding
0.43	GO:0042802	identical protein binding
0.34	GO:0003735	structural constituent of ribosome
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.41	GO:0005829	cytosol
0.38	GO:0005886	plasma membrane
0.37	GO:0005762	mitochondrial large ribosomal subunit
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.34

GO:0016773

tr|Q9DDT7|Q9DDT7_CHICK
Mitochondrial uncoupling protein
Search

UCP3

0.83	Mitochondrial uncoupling protein UCP

0.76	GO:0006839	mitochondrial transport
0.52	GO:0001666	response to hypoxia
0.52	GO:1990845	adaptive thermogenesis
0.51	GO:0051881	regulation of mitochondrial membrane potential
0.49	GO:0000303	response to superoxide
0.49	GO:0009409	response to cold
0.45	GO:0015992	proton transport
0.45	GO:0006631	fatty acid metabolic process
0.43	GO:0032868	response to insulin
0.42	GO:0007568	aging

0.60	GO:0017077	oxidative phosphorylation uncoupler activity
0.34	GO:0005515	protein binding
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.61	GO:0031966	mitochondrial membrane
0.42	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

tr|Q9DDU8|Q9DDU8_CHICK
Transformer-2 beta
Search

TRA2B

0.97	Transformer-2 protein like protein beta

0.58	GO:0021796	cerebral cortex regionalization
0.58	GO:1990403	embryonic brain development
0.58	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.57	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.56	GO:0071333	cellular response to glucose stimulus
0.55	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.51	GO:0000398	mRNA splicing, via spliceosome
0.50	GO:0051259	protein oligomerization
0.37	GO:0000302	response to reactive oxygen species
0.36	GO:0006508	proteolysis

0.59	GO:0003723	RNA binding
0.52	GO:0019904	protein domain specific binding
0.50	GO:0042802	identical protein binding
0.36	GO:0008233	peptidase activity
0.34	GO:0003872	6-phosphofructokinase activity

0.54	GO:0005637	nuclear inner membrane
0.52	GO:0005681	spliceosomal complex
0.49	GO:0005654	nucleoplasm
0.37	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0008233

tr|Q9DDW4|Q9DDW4_CHICK
Cited2/melanocyte specific gene-related gene 1 MRG1
Search

CITED2

0.91	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0001570	vasculogenesis
0.53	GO:0007179	transforming growth factor beta receptor signaling pathway
0.52	GO:0035802	adrenal cortex formation
0.52	GO:0060972	left/right pattern formation
0.52	GO:0048568	embryonic organ development
0.51	GO:0043009	chordate embryonic development
0.51	GO:0003006	developmental process involved in reproduction

0.54	GO:0001105	RNA polymerase II transcription coactivator activity
0.54	GO:0046332	SMAD binding
0.50	GO:0003682	chromatin binding
0.49	GO:0001102	RNA polymerase II activating transcription factor binding
0.47	GO:0050693	LBD domain binding
0.45	GO:0008022	protein C-terminus binding
0.43	GO:0044212	transcription regulatory region DNA binding
0.43	GO:0042803	protein homodimerization activity
0.42	GO:0003700	DNA binding transcription factor activity
0.39	GO:0019905	syntaxin binding

0.61	GO:0005634	nucleus
0.44	GO:0000785	chromatin
0.43	GO:0070013	intracellular organelle lumen
0.41	GO:0005829	cytosol

0.33

GO:0032041

sp|Q9DE07|NBN_CHICK
Nibrin
Search

NBN

0.92

Nibrin

0.78	GO:0007093	mitotic cell cycle checkpoint
0.77	GO:0000723	telomere maintenance
0.65	GO:0051321	meiotic cell cycle
0.64	GO:0006281	DNA repair
0.58	GO:0031572	G2 DNA damage checkpoint
0.57	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response
0.57	GO:0001325	formation of extrachromosomal circular DNA
0.56	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle
0.56	GO:1904354	negative regulation of telomere capping
0.56	GO:0002312	B cell activation involved in immune response

0.56	GO:0047485	protein N-terminus binding
0.50	GO:0008134	transcription factor binding
0.50	GO:0003684	damaged DNA binding
0.50	GO:0004003	ATP-dependent DNA helicase activity

0.82	GO:0030870	Mre11 complex
0.66	GO:0000781	chromosome, telomeric region
0.58	GO:0042405	nuclear inclusion body
0.54	GO:0016605	PML body
0.53	GO:0035861	site of double-strand break
0.50	GO:0044454	nuclear chromosome part
0.49	GO:0005657	replication fork
0.48	GO:0005730	nucleolus
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q9DE09|HMX1_CHICK
Homeobox protein HMX1
Search

0.73	Homeobox transcription factor SOHo

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0090596	sensory organ morphogenesis
0.48	GO:0007399	nervous system development
0.48	GO:0050885	neuromuscular process controlling balance
0.47	GO:0048839	inner ear development
0.47	GO:0007566	embryo implantation
0.47	GO:0048562	embryonic organ morphogenesis
0.47	GO:0060135	maternal process involved in female pregnancy

0.64	GO:0043565	sequence-specific DNA binding
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding
0.38	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q9DE13|BAZ2B_CHICK
Bromodomain adjacent to zinc finger domain protein 2B
Search

BAZ2B

0.89	Bromodomain adjacent to zinc finger domain protein 2B

0.37	GO:0016567	protein ubiquitination
0.34	GO:0097659	nucleic acid-templated transcription
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.34	GO:0010467	gene expression
0.34	GO:0034645	cellular macromolecule biosynthetic process

0.53	GO:0003677	DNA binding
0.52	GO:0046872	metal ion binding
0.37	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0005515	protein binding

0.59

GO:0005634

nucleus

0.37

GO:0004842

tr|Q9DE64|Q9DE64_CHICK
p95-APP2
Search

GIT2

0.92	G protein-coupled receptor kinase interacting ArfGAP 2

0.75	GO:0043547	positive regulation of GTPase activity
0.39	GO:0042074	cell migration involved in gastrulation
0.37	GO:0016310	phosphorylation
0.36	GO:0022604	regulation of cell morphogenesis
0.36	GO:0048266	behavioral response to pain
0.35	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway

0.76	GO:0005096	GTPase activator activity
0.50	GO:0046872	metal ion binding
0.38	GO:0016301	kinase activity
0.36	GO:0048365	Rac GTPase binding
0.35	GO:0019901	protein kinase binding
0.34	GO:0032403	protein complex binding

0.48	GO:0005654	nucleoplasm
0.37	GO:0005925	focal adhesion
0.34	GO:0031410	cytoplasmic vesicle
0.33	GO:0043234	protein complex

sp|Q9DEA3|PCNA_CHICK
Proliferating cell nuclear antigen
Search

PCNA

0.66	Proliferating cell nuclear antigen

0.76	GO:0006275	regulation of DNA replication
0.65	GO:0006260	DNA replication
0.58	GO:0019985	translesion synthesis
0.57	GO:0032077	positive regulation of deoxyribonuclease activity
0.56	GO:0045739	positive regulation of DNA repair
0.55	GO:0034644	cellular response to UV
0.52	GO:0030855	epithelial cell differentiation
0.52	GO:0006298	mismatch repair
0.49	GO:0010557	positive regulation of macromolecule biosynthetic process
0.49	GO:0031328	positive regulation of cellular biosynthetic process

0.84	GO:0030337	DNA polymerase processivity factor activity
0.59	GO:0000701	purine-specific mismatch base pair DNA N-glycosylase activity
0.59	GO:0032405	MutLalpha complex binding
0.58	GO:0032139	dinucleotide insertion or deletion binding
0.57	GO:0070182	DNA polymerase binding
0.57	GO:0035035	histone acetyltransferase binding
0.56	GO:0030971	receptor tyrosine kinase binding
0.52	GO:0003682	chromatin binding
0.50	GO:0042802	identical protein binding
0.50	GO:0003684	damaged DNA binding

0.61	GO:0070557	PCNA-p21 complex
0.59	GO:0043626	PCNA complex
0.54	GO:0043596	nuclear replication fork
0.52	GO:0005813	centrosome
0.52	GO:0016604	nuclear body
0.38	GO:0005652	nuclear lamina
0.37	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.36	GO:0000784	nuclear chromosome, telomeric region
0.36	GO:0070062	extracellular exosome
0.34	GO:0005663	DNA replication factor C complex

0.59

EC:3.2.2

GO:0000701

tr|Q9DEB1|Q9DEB1_CHICK
Transcription factor Gbx-1
Search

GBX1

0.78	LOW QUALITY PROTEIN: homeobox protein GBX-1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0007417	central nervous system development
0.54	GO:0007411	axon guidance
0.53	GO:0048513	animal organ development
0.52	GO:0021903	rostrocaudal neural tube patterning
0.50	GO:0019230	proprioception
0.50	GO:0060322	head development
0.50	GO:0001569	branching involved in blood vessel morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.49	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.48	GO:0001047	core promoter binding
0.47	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q9DEB6|CDX1_CHICK
Homeobox protein CDX-1
Search

CDX1

0.93	Homeobox protein CHOX-CAD

0.66	GO:0007275	multicellular organism development
0.61	GO:0014807	regulation of somitogenesis
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.52	GO:0009653	anatomical structure morphogenesis
0.52	GO:1902680	positive regulation of RNA biosynthetic process
0.51	GO:0006366	transcription by RNA polymerase II
0.46	GO:0030154	cell differentiation
0.40	GO:0035019	somatic stem cell population maintenance

0.63	GO:0043565	sequence-specific DNA binding
0.57	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.57	GO:0035326	enhancer binding
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.39	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.39	GO:0003714	transcription corepressor activity
0.33	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.39	GO:0017053	transcriptional repressor complex
0.38	GO:0000793	condensed chromosome
0.37	GO:0043233	organelle lumen
0.35	GO:0043234	protein complex
0.35	GO:0044446	intracellular organelle part

tr|Q9DEB8|Q9DEB8_CHICK
Protein Wnt
Search

sp|Q9DED6|BAX1B_CHICK
Homeobox protein BarH-like 1b
Search

BARX1

0.97	BARX homeobox 1

0.58	GO:0048536	spleen development
0.58	GO:0009888	tissue development
0.58	GO:0055123	digestive system development
0.56	GO:0030178	negative regulation of Wnt signaling pathway
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0009952	anterior/posterior pattern specification
0.55	GO:0010468	regulation of gene expression
0.55	GO:0030154	cell differentiation
0.53	GO:0006366	transcription by RNA polymerase II

0.63	GO:0043565	sequence-specific DNA binding
0.56	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding
0.46	GO:0003682	chromatin binding
0.32	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.45	GO:0005667	transcription factor complex
0.43	GO:0005829	cytosol
0.43	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part

sp|Q9DEE9|ARP6_CHICK
Actin-related protein 6
Search

ACTR6

0.94	ARP6 actin-related protein 6 homolog (Yeast)

0.78

GO:0006338

chromatin remodeling

0.34

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.36	GO:0005856	cytoskeleton
0.33	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q9DEQ4|SFRP1_CHICK
Secreted frizzled-related protein 1
Search

SFRP1

0.96	Secreted frizzled-related protein 1

0.73	GO:0016055	Wnt signaling pathway
0.69	GO:0007275	multicellular organism development
0.69	GO:0030510	regulation of BMP signaling pathway
0.67	GO:0030111	regulation of Wnt signaling pathway
0.59	GO:0045578	negative regulation of B cell differentiation
0.58	GO:0071504	cellular response to heparin
0.58	GO:0033689	negative regulation of osteoblast proliferation
0.57	GO:2000271	positive regulation of fibroblast apoptotic process
0.57	GO:2000270	negative regulation of fibroblast apoptotic process
0.57	GO:0061469	regulation of type B pancreatic cell proliferation

0.60	GO:0017147	Wnt-protein binding
0.56	GO:0005109	frizzled binding
0.53	GO:0008201	heparin binding
0.51	GO:0042813	Wnt-activated receptor activity
0.50	GO:0004197	cysteine-type endopeptidase activity
0.50	GO:0042802	identical protein binding
0.46	GO:0004930	G-protein coupled receptor activity
0.41	GO:0008144	drug binding

0.65	GO:0005576	extracellular region
0.50	GO:0009986	cell surface
0.47	GO:0005829	cytosol
0.35	GO:0031982	vesicle
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.50

EC:3.4.22

GO:0004197

tr|Q9DEQ5|Q9DEQ5_CHICK
p37NB protein (Fragment)
Search

LRRC17

0.97	Leucine-rich repeat-containing protein 17

0.86	GO:0048539	bone marrow development
0.85	GO:0045671	negative regulation of osteoclast differentiation
0.49	GO:0033687	osteoblast proliferation
0.47	GO:0001649	osteoblast differentiation
0.38	GO:0051965	positive regulation of synapse assembly
0.35	GO:0046426	negative regulation of JAK-STAT cascade
0.34	GO:0006469	negative regulation of protein kinase activity
0.34	GO:0019221	cytokine-mediated signaling pathway
0.34	GO:0007265	Ras protein signal transduction
0.34	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway

0.35	GO:0005102	receptor binding
0.34	GO:0004860	protein kinase inhibitor activity
0.33	GO:0004016	adenylate cyclase activity
0.33	GO:0099103	channel activator activity
0.33	GO:0015459	potassium channel regulator activity
0.33	GO:0044325	ion channel binding
0.33	GO:0016500	protein-hormone receptor activity
0.33	GO:0005249	voltage-gated potassium channel activity
0.33	GO:0050661	NADP binding
0.32	GO:0004930	G-protein coupled receptor activity

0.72	GO:0005615	extracellular space
0.37	GO:0044300	cerebellar mossy fiber
0.33	GO:0042734	presynaptic membrane
0.33	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0030054	cell junction
0.33	GO:0008076	voltage-gated potassium channel complex
0.32	GO:0005739	mitochondrion

0.33

EC:4.6.1.1

GO:0004016

tr|Q9DEQ6|Q9DEQ6_CHICK
Eukaryote initiation factor 2 beta
Search

EIF2S2

0.92	Eukaryotic translation initiation factor 2 subunit beta

0.70	GO:0006413	translational initiation
0.53	GO:0002176	male germ cell proliferation
0.49	GO:0008584	male gonad development
0.45	GO:0001701	in utero embryonic development
0.32	GO:0055085	transmembrane transport

0.70	GO:0003743	translation initiation factor activity
0.35	GO:0005515	protein binding
0.35	GO:0046872	metal ion binding

0.53	GO:0005850	eukaryotic translation initiation factor 2 complex
0.34	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q9DEQ9|MSGN1_CHICK
Mesogenin-1
Search

MSGN1

0.97	BHLH transcription factor pMesogenin2

0.61	GO:0001756	somitogenesis
0.59	GO:0007379	segment specification
0.57	GO:0006366	transcription by RNA polymerase II
0.56	GO:0045944	positive regulation of transcription by RNA polymerase II
0.54	GO:0001707	mesoderm formation
0.52	GO:0009880	embryonic pattern specification
0.46	GO:0009887	animal organ morphogenesis
0.44	GO:0007507	heart development
0.44	GO:0030154	cell differentiation
0.43	GO:0060485	mesenchyme development

0.68	GO:0046983	protein dimerization activity
0.59	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.53	GO:0003682	chromatin binding
0.51	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0035326	enhancer binding
0.39	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.34	GO:0004518	nuclease activity

0.43	GO:0005634	nucleus
0.34	GO:0070062	extracellular exosome

0.34

EC:3.1

GO:0004518

tr|Q9DER1|Q9DER1_CHICK
Angiopoietin-2B
Search

ANGPT2

0.95	Angiopoietin 2

0.69	GO:0048014	Tie signaling pathway
0.62	GO:0001525	angiogenesis
0.60	GO:0050928	negative regulation of positive chemotaxis
0.60	GO:0043535	regulation of blood vessel endothelial cell migration
0.57	GO:0007162	negative regulation of cell adhesion
0.56	GO:0010596	negative regulation of endothelial cell migration
0.54	GO:0016525	negative regulation of angiogenesis
0.54	GO:0010810	regulation of cell-substrate adhesion
0.49	GO:0072012	glomerulus vasculature development
0.48	GO:2000446	regulation of macrophage migration inhibitory factor signaling pathway

0.85	GO:0030971	receptor tyrosine kinase binding
0.35	GO:0005172	vascular endothelial growth factor receptor binding
0.35	GO:0046872	metal ion binding
0.34	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.53	GO:0005615	extracellular space
0.46	GO:0005902	microvillus
0.44	GO:0098857	membrane microdomain
0.38	GO:0005886	plasma membrane
0.35	GO:0005634	nucleus
0.34	GO:1903561	extracellular vesicle

sp|Q9DER5|TEN2_CHICK
Teneurin-2
Search

TENM2

0.95	Teneurin transmembrane protein 2

0.78	GO:0097264	self proteolysis
0.57	GO:0007165	signal transduction
0.48	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.45	GO:0048666	neuron development
0.44	GO:0000902	cell morphogenesis
0.40	GO:0051491	positive regulation of filopodium assembly
0.38	GO:0032990	cell part morphogenesis
0.38	GO:0000122	negative regulation of transcription by RNA polymerase II
0.38	GO:0120036	plasma membrane bounded cell projection organization
0.37	GO:0006935	chemotaxis

0.54	GO:0005509	calcium ion binding
0.46	GO:0050839	cell adhesion molecule binding
0.44	GO:0042803	protein homodimerization activity
0.44	GO:0046982	protein heterodimerization activity
0.37	GO:0005102	receptor binding
0.30	GO:0003824	catalytic activity

0.67	GO:0005887	integral component of plasma membrane
0.45	GO:0043005	neuron projection
0.39	GO:0016605	PML body
0.39	GO:0030175	filopodium
0.38	GO:0030427	site of polarized growth
0.38	GO:0036477	somatodendritic compartment
0.38	GO:0045211	postsynaptic membrane
0.38	GO:0005911	cell-cell junction
0.38	GO:0120038	plasma membrane bounded cell projection part
0.37	GO:0005794	Golgi apparatus

sp|Q9DER7|TLL1_CHICK
Tolloid-like protein 1
Search

TLL1

0.63	Metalloendopeptidase

0.60	GO:0006508	proteolysis
0.47	GO:0035124	embryonic caudal fin morphogenesis
0.47	GO:0048264	determination of ventral identity
0.45	GO:0036342	post-anal tail morphogenesis
0.45	GO:0001885	endothelial cell development
0.45	GO:0030513	positive regulation of BMP signaling pathway
0.45	GO:0035162	embryonic hemopoiesis
0.44	GO:0001707	mesoderm formation
0.43	GO:0001568	blood vessel development
0.35	GO:0045332	phospholipid translocation

0.69	GO:0004222	metalloendopeptidase activity
0.69	GO:0005509	calcium ion binding
0.62	GO:0008270	zinc ion binding
0.35	GO:0004012	phospholipid-translocating ATPase activity
0.34	GO:0000287	magnesium ion binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0005518	collagen binding

0.30

GO:0031224

intrinsic component of membrane

0.69

GO:0004222

tr|Q9DF37|Q9DF37_CHICK
Tandem PH domain-containing protein-2
Search

PLEKHA2

0.97	Pleckstrin like proteiny domain-containing family A member 2

0.46	GO:0001954	positive regulation of cell-matrix adhesion
0.38	GO:0006661	phosphatidylinositol biosynthetic process
0.36	GO:0001558	regulation of cell growth
0.36	GO:0006508	proteolysis
0.36	GO:0032065	cortical protein anchoring

0.84	GO:0030165	PDZ domain binding
0.84	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.47	GO:0001968	fibronectin binding
0.46	GO:0043236	laminin binding
0.37	GO:0005520	insulin-like growth factor binding
0.36	GO:0004175	endopeptidase activity
0.35	GO:0017171	serine hydrolase activity
0.35	GO:0008237	metallopeptidase activity

0.42	GO:0005737	cytoplasm
0.39	GO:0005634	nucleus
0.39	GO:0043234	protein complex
0.38	GO:0071944	cell periphery
0.35	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|Q9DF58|Q9DF58_CHICK
Integrin-linked kinase
Search

ILK

0.96	Integrin-linked protein kinase

0.72	GO:0007229	integrin-mediated signaling pathway
0.61	GO:0006468	protein phosphorylation
0.60	GO:0034446	substrate adhesion-dependent cell spreading
0.59	GO:0010761	fibroblast migration
0.58	GO:2000178	negative regulation of neural precursor cell proliferation
0.58	GO:0043491	protein kinase B signaling
0.58	GO:0032292	peripheral nervous system axon ensheathment
0.58	GO:0001658	branching involved in ureteric bud morphogenesis
0.58	GO:1901224	positive regulation of NIK/NF-kappaB signaling
0.58	GO:0014044	Schwann cell development

0.62	GO:0004672	protein kinase activity
0.53	GO:0019901	protein kinase binding
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0004871	signal transducer activity
0.39	GO:0005178	integrin binding
0.38	GO:0017124	SH3 domain binding

0.58	GO:0005925	focal adhesion
0.57	GO:0030027	lamellipodium
0.49	GO:0005654	nucleoplasm
0.49	GO:0097517	contractile actin filament bundle
0.49	GO:0042641	actomyosin
0.49	GO:0005829	cytosol
0.45	GO:0030017	sarcomere
0.40	GO:0042383	sarcolemma
0.39	GO:0043034	costamere
0.39	GO:0043198	dendritic shaft

sp|Q9DF69|CSPG5_CHICK
Chondroitin sulfate proteoglycan 5
Search

CSPG5

0.95	Chondroitin sulfate proteoglycan 5

0.50	GO:0050804	modulation of chemical synaptic transmission
0.41	GO:0040008	regulation of growth
0.40	GO:0007399	nervous system development
0.40	GO:0030154	cell differentiation
0.36	GO:0030207	chondroitin sulfate catabolic process
0.36	GO:0030208	dermatan sulfate biosynthetic process
0.35	GO:0030206	chondroitin sulfate biosynthetic process
0.35	GO:0048678	response to axon injury
0.35	GO:0031099	regeneration
0.34	GO:0120036	plasma membrane bounded cell projection organization

0.34

GO:0008083

growth factor activity

0.48	GO:0030660	Golgi-associated vesicle membrane
0.46	GO:0005794	Golgi apparatus
0.37	GO:0009986	cell surface
0.36	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0005886	plasma membrane
0.35	GO:0043202	lysosomal lumen
0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|Q9DFH3|Q9DFH3_CHICK
Xenobiotic receptor
Search

NR1I3

0.87	Constitutive androstane nuclear receptor

0.77	GO:0043401	steroid hormone mediated signaling pathway
0.69	GO:0030522	intracellular receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0051254	positive regulation of RNA metabolic process
0.51	GO:0010557	positive regulation of macromolecule biosynthetic process
0.51	GO:0031328	positive regulation of cellular biosynthetic process
0.50	GO:0051253	negative regulation of RNA metabolic process

0.78	GO:0003707	steroid hormone receptor activity
0.71	GO:0004879	nuclear receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding
0.50	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.45	GO:0046965	retinoid X receptor binding
0.37	GO:0035326	enhancer binding
0.36	GO:0008144	drug binding

0.61	GO:0005634	nucleus
0.49	GO:0070013	intracellular organelle lumen
0.44	GO:0044446	intracellular organelle part
0.43	GO:0005829	cytosol
0.41	GO:0005667	transcription factor complex
0.41	GO:0045111	intermediate filament cytoskeleton
0.38	GO:0005694	chromosome
0.33	GO:0043235	receptor complex
0.33	GO:0098636	protein complex involved in cell adhesion
0.33	GO:0005887	integral component of plasma membrane

0.32

EC:1.97.1

GO:0051353

sp|Q9DFZ3|CHUR_CHICK
Protein Churchill
Search

CHURC1

0.97	Churchill domain containing 1

0.73	GO:0045893	positive regulation of transcription, DNA-templated
0.70	GO:0007275	multicellular organism development
0.39	GO:0006351	transcription, DNA-templated
0.37	GO:0009888	tissue development
0.37	GO:0042661	regulation of mesodermal cell fate specification
0.37	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway
0.36	GO:0008543	fibroblast growth factor receptor signaling pathway
0.36	GO:0030336	negative regulation of cell migration
0.36	GO:0001667	ameboidal-type cell migration
0.35	GO:0048646	anatomical structure formation involved in morphogenesis

0.63	GO:0008270	zinc ion binding
0.33	GO:0003677	DNA binding

0.34

GO:0005634

nucleus

tr|Q9DG07|Q9DG07_CHICK
SLP-76 adaptor protein
Search

LCP2

0.97	Lymphocyte cytosolic protein 2

0.85	GO:0045576	mast cell activation
0.84	GO:0050663	cytokine secretion
0.84	GO:0050852	T cell receptor signaling pathway
0.77	GO:0045860	positive regulation of protein kinase activity
0.61	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.58	GO:0006955	immune response
0.51	GO:0035556	intracellular signal transduction
0.40	GO:0038095	Fc-epsilon receptor signaling pathway
0.39	GO:0030168	platelet activation
0.36	GO:0043551	regulation of phosphatidylinositol 3-kinase activity

0.46	GO:0023027	MHC class I protein binding, via antigen binding groove
0.36	GO:0035014	phosphatidylinositol 3-kinase regulator activity
0.33	GO:0003779	actin binding
0.33	GO:0008269	JAK pathway signal transduction adaptor activity
0.33	GO:0005159	insulin-like growth factor receptor binding
0.32	GO:0016301	kinase activity

0.87	GO:0036398	TCR signalosome
0.82	GO:0044853	plasma membrane raft
0.74	GO:0005911	cell-cell junction
0.67	GO:0005829	cytosol
0.36	GO:0005942	phosphatidylinositol 3-kinase complex
0.33	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|Q9DG09|STAR_CHICK
Steroidogenic acute regulatory protein, mitochondrial
Search

STAR

0.92	Steroidogenic acute regulatory protein, mitochondrial

0.83	GO:0030301	cholesterol transport
0.76	GO:0006694	steroid biosynthetic process
0.62	GO:1904253	positive regulation of bile acid metabolic process
0.61	GO:0070857	regulation of bile acid biosynthetic process
0.61	GO:0008211	glucocorticoid metabolic process
0.60	GO:0010893	positive regulation of steroid biosynthetic process
0.52	GO:0031328	positive regulation of cellular biosynthetic process
0.47	GO:0044255	cellular lipid metabolic process
0.47	GO:0008203	cholesterol metabolic process
0.40	GO:0042747	circadian sleep/wake cycle, REM sleep

0.85	GO:0017127	cholesterol transporter activity
0.82	GO:0015485	cholesterol binding
0.34	GO:0005515	protein binding

0.60	GO:0005739	mitochondrion
0.38	GO:0043025	neuronal cell body
0.38	GO:0031970	organelle envelope lumen
0.37	GO:0043005	neuron projection
0.36	GO:0005829	cytosol
0.35	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

sp|Q9DG23|POPD1_CHICK
Blood vessel epicardial substance
Search

BVES

0.94	Blood vessel epicardial substance-A

0.59	GO:0090136	epithelial cell-cell adhesion
0.57	GO:0007519	skeletal muscle tissue development
0.56	GO:0001921	positive regulation of receptor recycling
0.56	GO:0060931	sinoatrial node cell development
0.55	GO:0002931	response to ischemia
0.55	GO:0034446	substrate adhesion-dependent cell spreading
0.54	GO:2001135	regulation of endocytic recycling
0.54	GO:0060973	cell migration involved in heart development
0.52	GO:0040017	positive regulation of locomotion
0.52	GO:0002027	regulation of heart rate

0.53	GO:0030552	cAMP binding
0.46	GO:0005198	structural molecule activity
0.35	GO:0005515	protein binding

0.57	GO:0042383	sarcolemma
0.57	GO:0016328	lateral plasma membrane
0.55	GO:0005923	bicellular tight junction
0.53	GO:0005901	caveola
0.51	GO:0031253	cell projection membrane
0.42	GO:0044214	spanning component of plasma membrane
0.40	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0031227	intrinsic component of endoplasmic reticulum membrane

sp|Q9DG25|POPD3_CHICK
Popeye domain-containing protein 3
Search

POPDC3

0.93	Popeye domain-containing protein 3

0.50	GO:0042391	regulation of membrane potential
0.39	GO:0061337	cardiac conduction
0.39	GO:0001947	heart looping
0.38	GO:0051146	striated muscle cell differentiation
0.34	GO:0006470	protein dephosphorylation

0.53	GO:0030552	cAMP binding
0.35	GO:0008138	protein tyrosine/serine/threonine phosphatase activity

0.42	GO:0042383	sarcolemma
0.30	GO:0016021	integral component of membrane

0.35

EC:3.1.3

GO:0008138

tr|Q9DG28|Q9DG28_CHICK
Rod-type transducin alpha subunit
Search

GNAT1

0.79	Short photoreceptor transducin-alpha subunit

0.82	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.60	GO:0050908	detection of light stimulus involved in visual perception
0.60	GO:0050917	sensory perception of umami taste
0.57	GO:0042462	eye photoreceptor cell development
0.56	GO:0060041	retina development in camera-type eye
0.55	GO:0071257	cellular response to electrical stimulus
0.54	GO:0007602	phototransduction
0.50	GO:0050913	sensory perception of bitter taste
0.50	GO:0008283	cell proliferation
0.48	GO:0050912	detection of chemical stimulus involved in sensory perception of taste

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0001664	G-protein coupled receptor binding
0.37	GO:0000035	acyl binding
0.36	GO:0046872	metal ion binding

0.61	GO:0001917	photoreceptor inner segment
0.60	GO:0001750	photoreceptor outer segment
0.53	GO:0032391	photoreceptor connecting cilium
0.50	GO:1905360	GTPase complex
0.50	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.44	GO:0098797	plasma membrane protein complex
0.40	GO:0098590	plasma membrane region
0.40	GO:0045177	apical part of cell
0.38	GO:0043025	neuronal cell body
0.38	GO:0030141	secretory granule

sp|Q9DG45|PHS2_CHICK
Pterin-4-alpha-carbinolamine dehydratase 2
Search

PCBD2

0.97	Pterin-4-alpha-carbinolamine dehydratase 2

0.80	GO:0046146	tetrahydrobiopterin metabolic process
0.80	GO:0034312	diol biosynthetic process
0.72	GO:0042559	pteridine-containing compound biosynthetic process
0.65	GO:0009108	coenzyme biosynthetic process
0.53	GO:0051291	protein heterooligomerization
0.53	GO:0051289	protein homotetramerization
0.46	GO:0045893	positive regulation of transcription, DNA-templated
0.39	GO:0055114	oxidation-reduction process
0.34	GO:0006351	transcription, DNA-templated
0.33	GO:0045454	cell redox homeostasis

0.81	GO:0008124	4-alpha-hydroxytetrahydrobiopterin dehydratase activity
0.53	GO:0004505	phenylalanine 4-monooxygenase activity
0.37	GO:0042802	identical protein binding
0.34	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0003677	DNA binding

0.43	GO:0005634	nucleus
0.42	GO:0005739	mitochondrion
0.36	GO:0005829	cytosol
0.36	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.81	EC:4.2.1.96	GO:0008124
0.81	KEGG:R04734	GO:0008124

sp|Q9DG58|GLL3_CHICK
Gallinacin-3
Search

0.85	Beta-defensin prepropeptide

0.72	GO:0006952	defense response
0.52	GO:0009617	response to bacterium

0.66

GO:0005576

extracellular region

sp|Q9DG67|RA54B_CHICK
DNA repair and recombination protein RAD54B
Search

RAD54B

0.86	LOW QUALITY PROTEIN: DNA repair and recombination protein RAD54B

0.57	GO:0008340	determination of adult lifespan
0.56	GO:0010212	response to ionizing radiation
0.54	GO:0000724	double-strand break repair via homologous recombination
0.50	GO:0042493	response to drug
0.36	GO:0007165	signal transduction
0.36	GO:0007131	reciprocal meiotic recombination
0.35	GO:0006312	mitotic recombination
0.35	GO:0032508	DNA duplex unwinding
0.35	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.34	GO:0030491	heteroduplex formation

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0015616	DNA translocase activity
0.37	GO:0003924	GTPase activity
0.37	GO:0032550	purine ribonucleoside binding
0.37	GO:0032561	guanyl ribonucleotide binding
0.36	GO:0004386	helicase activity
0.35	GO:0003677	DNA binding
0.34	GO:0005515	protein binding

0.36	GO:0005634	nucleus
0.33	GO:0016282	eukaryotic 43S preinitiation complex
0.33	GO:0033290	eukaryotic 48S preinitiation complex
0.33	GO:0005852	eukaryotic translation initiation factor 3 complex
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.31

EC:2

GO:0016740

sp|Q9DGB6|TLR22_CHICK
Toll-like receptor 2 type-2
Search

TLR2

0.79	Toll like receptor 2

0.86	GO:0034134	toll-like receptor 2 signaling pathway
0.84	GO:0050729	positive regulation of inflammatory response
0.84	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
0.82	GO:0050707	regulation of cytokine secretion
0.82	GO:0002237	response to molecule of bacterial origin
0.80	GO:0006954	inflammatory response
0.79	GO:0045087	innate immune response
0.49	GO:0002374	cytokine secretion involved in immune response
0.49	GO:0032613	interleukin-10 production
0.49	GO:0016045	detection of bacterium

0.50	GO:0042497	triacyl lipopeptide binding
0.48	GO:0035325	Toll-like receptor binding
0.47	GO:0038187	pattern recognition receptor activity
0.46	GO:0001530	lipopolysaccharide binding
0.44	GO:0042834	peptidoglycan binding
0.44	GO:0032403	protein complex binding
0.43	GO:0046982	protein heterodimerization activity
0.41	GO:0038023	signaling receptor activity
0.35	GO:0042498	diacyl lipopeptide binding
0.35	GO:0070891	lipoteichoic acid binding

0.49	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex
0.47	GO:0098857	membrane microdomain
0.44	GO:0009986	cell surface
0.44	GO:0005794	Golgi apparatus
0.43	GO:0031226	intrinsic component of plasma membrane
0.41	GO:0030670	phagocytic vesicle membrane
0.37	GO:0044297	cell body
0.36	GO:0106003	amyloid-beta complex
0.35	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex
0.35	GO:0042995	cell projection

sp|Q9DGD1|MGT4C_CHICK
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C
Search

MGAT4C

0.95	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C

0.60	GO:0005975	carbohydrate metabolic process
0.38	GO:0043413	macromolecule glycosylation
0.38	GO:0009101	glycoprotein biosynthetic process
0.36	GO:0006464	cellular protein modification process
0.34	GO:0007186	G-protein coupled receptor signaling pathway

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.39	GO:0140103	catalytic activity, acting on a glycoprotein
0.38	GO:0008194	UDP-glycosyltransferase activity
0.35	GO:0046872	metal ion binding
0.34	GO:0004930	G-protein coupled receptor activity

0.38	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0016758

sp|Q9DGG6|ADCY9_CHICK
Adenylate cyclase type 9
Search

ADCY9

0.92	Adenylate cyclase type 9

0.76	GO:0009190	cyclic nucleotide biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.58	GO:0071875	adrenergic receptor signaling pathway
0.57	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.56	GO:0046058	cAMP metabolic process
0.50	GO:0009152	purine ribonucleotide biosynthetic process
0.47	GO:0046068	cGMP metabolic process
0.36	GO:0034199	activation of protein kinase A activity
0.36	GO:0071377	cellular response to glucagon stimulus
0.36	GO:0003091	renal water homeostasis

0.75	GO:0016849	phosphorus-oxygen lyase activity
0.57	GO:0009975	cyclase activity
0.52	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0008144	drug binding
0.35	GO:0046872	metal ion binding
0.34	GO:0043168	anion binding

0.49	GO:0008074	guanylate cyclase complex, soluble
0.49	GO:0005887	integral component of plasma membrane
0.38	GO:0030425	dendrite
0.38	GO:0030424	axon

0.75

EC:4.6

GO:0016849

tr|Q9DGL8|Q9DGL8_CHICK
Jun-suppressed chemokine
Search

CXCL14

0.97	C-X-C motif chemokine ligand 14

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.62	GO:2000503	positive regulation of natural killer cell chemotaxis
0.59	GO:0045662	negative regulation of myoblast differentiation
0.56	GO:0048839	inner ear development
0.45	GO:0007267	cell-cell signaling
0.36	GO:0031640	killing of cells of other organism
0.36	GO:0010469	regulation of receptor activity
0.35	GO:0043207	response to external biotic stimulus
0.33	GO:0007165	signal transduction

0.84	GO:0008009	chemokine activity
0.34	GO:0046983	protein dimerization activity

0.66	GO:0005576	extracellular region
0.51	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

tr|Q9DGN6|Q9DGN6_CHICK
Endothelin converting enzyme-1
Search

ECE1

0.76	Endothelin converting enzyme

0.85	GO:0016486	peptide hormone processing
0.56	GO:0010814	substance P catabolic process
0.56	GO:0010816	calcitonin catabolic process
0.55	GO:0010815	bradykinin catabolic process
0.54	GO:0001921	positive regulation of receptor recycling
0.53	GO:0060037	pharyngeal system development
0.53	GO:0002002	regulation of angiotensin levels in blood
0.52	GO:0042733	embryonic digit morphogenesis
0.50	GO:0043583	ear development
0.49	GO:0007507	heart development

0.70	GO:0004222	metalloendopeptidase activity
0.48	GO:0042803	protein homodimerization activity
0.43	GO:0008270	zinc ion binding
0.35	GO:0017046	peptide hormone binding
0.34	GO:0000339	RNA cap binding
0.33	GO:0003743	translation initiation factor activity

0.55	GO:0033093	Weibel-Palade body
0.50	GO:0009897	external side of plasma membrane
0.49	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0005768	endosome
0.39	GO:0044433	cytoplasmic vesicle part
0.38	GO:0012506	vesicle membrane
0.36	GO:0005765	lysosomal membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0031300	intrinsic component of organelle membrane
0.34	GO:0005794	Golgi apparatus

0.70

GO:0004222

tr|Q9I878|Q9I878_CHICK
Peroxisome proliferator-activated receptor
Search

PPARG

0.93	Peroxisome proliferator-activated receptor gamma

0.79	GO:0048511	rhythmic process
0.79	GO:0030522	intracellular receptor signaling pathway
0.77	GO:0043401	steroid hormone mediated signaling pathway
0.60	GO:0045713	low-density lipoprotein particle receptor biosynthetic process
0.60	GO:0010742	macrophage derived foam cell differentiation
0.59	GO:1905563	negative regulation of vascular endothelial cell proliferation
0.59	GO:1905461	positive regulation of vascular associated smooth muscle cell apoptotic process
0.58	GO:0010887	negative regulation of cholesterol storage
0.58	GO:0060331	negative regulation of response to interferon-gamma
0.58	GO:0010871	negative regulation of receptor biosynthetic process

0.82	GO:0004879	nuclear receptor activity
0.78	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.59	GO:0050692	DBD domain binding
0.58	GO:0050693	LBD domain binding
0.58	GO:0046965	retinoid X receptor binding
0.56	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.56	GO:0051393	alpha-actinin binding
0.55	GO:0043621	protein self-association

0.61	GO:0005634	nucleus
0.50	GO:0005667	transcription factor complex
0.48	GO:0005737	cytoplasm
0.43	GO:0044446	intracellular organelle part
0.34	GO:0070013	intracellular organelle lumen
0.30	GO:0016021	integral component of membrane

tr|Q9I882|Q9I882_CHICK
Protein kinase C inhibitor
Search

HINT1

0.54	Histidine triad nucleotide-binding protein 1

0.52	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.51	GO:0009154	purine ribonucleotide catabolic process
0.47	GO:0050850	positive regulation of calcium-mediated signaling
0.41	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression
0.37	GO:0006351	transcription, DNA-templated
0.33	GO:0016310	phosphorylation

0.38	GO:0016787	hydrolase activity
0.36	GO:0005080	protein kinase C binding
0.36	GO:1901265	nucleoside phosphate binding
0.35	GO:0036094	small molecule binding
0.33	GO:0016301	kinase activity

0.50	GO:0000118	histone deacetylase complex
0.44	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.34	GO:0005856	cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

0.38

GO:0016787

sp|Q9I8C7|ACH10_CHICK
Neuronal acetylcholine receptor subunit alpha-10
Search

0.81	Cholinergic receptor nicotinic alpha 9 subunit

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.49	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
0.47	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.47	GO:0042472	inner ear morphogenesis
0.39	GO:0006812	cation transport
0.37	GO:0007271	synaptic transmission, cholinergic

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.46	GO:0005892	acetylcholine-gated channel complex

sp|Q9I8D0|VPP1_CHICK
V-type proton ATPase 116 kDa subunit a isoform 1
Search

ATP6V0A1

0.58	V-type proton ATPase subunit a

0.75	GO:0015991	ATP hydrolysis coupled proton transport
0.53	GO:0016241	regulation of macroautophagy
0.51	GO:1901998	toxin transport
0.46	GO:0007035	vacuolar acidification
0.46	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly
0.42	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.42	GO:0006754	ATP biosynthetic process
0.39	GO:0090382	phagosome maturation
0.38	GO:0097352	autophagosome maturation
0.37	GO:0001755	neural crest cell migration

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.56	GO:0051117	ATPase binding
0.45	GO:0036442	proton-exporting ATPase activity
0.42	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism

0.83	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain
0.51	GO:0016607	nuclear speck
0.47	GO:0005794	Golgi apparatus
0.46	GO:0005829	cytosol
0.45	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.42	GO:0042470	melanosome
0.42	GO:0005886	plasma membrane
0.40	GO:0030659	cytoplasmic vesicle membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:0099503	secretory vesicle

sp|Q9I8D1|MYO6_CHICK
Unconventional myosin-VI
Search

MYO6

0.94	Unconventional myosin-VI

0.74	GO:0007018	microtubule-based movement
0.53	GO:0030330	DNA damage response, signal transduction by p53 class mediator
0.50	GO:0051046	regulation of secretion
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II
0.47	GO:0006897	endocytosis
0.43	GO:0035479	angioblast cell migration from lateral mesoderm to midline
0.43	GO:0050954	sensory perception of mechanical stimulus
0.42	GO:0042491	inner ear auditory receptor cell differentiation
0.42	GO:0048844	artery morphogenesis
0.40	GO:0050982	detection of mechanical stimulus

0.77	GO:0051015	actin filament binding
0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0045296	cadherin binding
0.38	GO:0005516	calmodulin binding
0.37	GO:0042802	identical protein binding
0.37	GO:0000146	microfilament motor activity

0.77	GO:0016459	myosin complex
0.53	GO:0031941	filamentous actin
0.52	GO:0045334	clathrin-coated endocytic vesicle
0.52	GO:0001726	ruffle
0.50	GO:0031965	nuclear membrane
0.50	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
0.47	GO:0005794	Golgi apparatus
0.39	GO:0005902	microvillus
0.39	GO:0031256	leading edge membrane

sp|Q9I8D8|CD40L_CHICK
CD40 ligand
Search

sp|Q9I8F4|TPD53_CHICK
Tumor protein D53 homolog
Search

TPD52L1

0.96	Tumor protein D52 like 1

0.68	GO:0030183	B cell differentiation
0.68	GO:0000086	G2/M transition of mitotic cell cycle
0.62	GO:0046330	positive regulation of JNK cascade
0.61	GO:2001235	positive regulation of apoptotic signaling pathway
0.60	GO:0043406	positive regulation of MAP kinase activity
0.42	GO:0008284	positive regulation of cell proliferation

0.73	GO:0042803	protein homodimerization activity
0.70	GO:0046982	protein heterodimerization activity
0.58	GO:0005509	calcium ion binding

0.77	GO:0048471	perinuclear region of cytoplasm
0.61	GO:0012505	endomembrane system
0.51	GO:0043227	membrane-bounded organelle
0.49	GO:0043229	intracellular organelle
0.30	GO:0016020	membrane

sp|Q9I8G9|RBBP7_CHICK
Histone-binding protein RBBP7
Search

RBBP7

0.88	Histone-binding protein RBBP7

0.53	GO:0070370	cellular heat acclimation
0.51	GO:0030308	negative regulation of cell growth
0.48	GO:0000122	negative regulation of transcription by RNA polymerase II
0.46	GO:0016569	covalent chromatin modification
0.43	GO:0006260	DNA replication
0.40	GO:0048545	response to steroid hormone
0.40	GO:0006351	transcription, DNA-templated
0.39	GO:0045814	negative regulation of gene expression, epigenetic
0.38	GO:0006338	chromatin remodeling
0.38	GO:0070317	negative regulation of G0 to G1 transition

0.41	GO:0003723	RNA binding
0.36	GO:0004407	histone deacetylase activity
0.36	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.51	GO:0017053	transcriptional repressor complex
0.50	GO:0034708	methyltransferase complex
0.48	GO:0031974	membrane-enclosed lumen
0.48	GO:0000785	chromatin
0.45	GO:1904949	ATPase complex
0.45	GO:0005829	cytosol
0.42	GO:0043234	protein complex

0.36

GO:0004407

sp|Q9I8I2|BOK_CHICK
Bcl-2-related ovarian killer protein
Search

BOK

0.97	Putative anti-apoptotic bcl-2 family prevent opening of mitochondrial porin channel

0.74	GO:0042981	regulation of apoptotic process
0.58	GO:0051902	negative regulation of mitochondrial depolarization
0.57	GO:1901382	regulation of chorionic trophoblast cell proliferation
0.57	GO:1903899	positive regulation of PERK-mediated unfolded protein response
0.57	GO:0006915	apoptotic process
0.57	GO:0060546	negative regulation of necroptotic process
0.55	GO:0010823	negative regulation of mitochondrion organization
0.55	GO:0070997	neuron death
0.54	GO:0046902	regulation of mitochondrial membrane permeability
0.54	GO:2001056	positive regulation of cysteine-type endopeptidase activity

0.52	GO:0042803	protein homodimerization activity
0.52	GO:0031625	ubiquitin protein ligase binding
0.49	GO:0005102	receptor binding
0.45	GO:0046982	protein heterodimerization activity
0.41	GO:0051400	BH domain binding
0.34	GO:0004197	cysteine-type endopeptidase activity

0.57	GO:0033106	cis-Golgi network membrane
0.55	GO:0032588	trans-Golgi network membrane
0.55	GO:0055038	recycling endosome membrane
0.54	GO:0031901	early endosome membrane
0.49	GO:0005789	endoplasmic reticulum membrane
0.46	GO:0031966	mitochondrial membrane
0.45	GO:0031968	organelle outer membrane
0.44	GO:0019866	organelle inner membrane
0.44	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.4.22

GO:0004197

sp|Q9I8K7|CITE3_CHICK
Cbp/p300-interacting transactivator 3
Search

0.96	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0051254	positive regulation of RNA metabolic process
0.48	GO:0010557	positive regulation of macromolecule biosynthetic process
0.48	GO:0031328	positive regulation of cellular biosynthetic process
0.48	GO:0043627	response to estrogen
0.46	GO:0035801	adrenal cortex development
0.46	GO:0006366	transcription by RNA polymerase II
0.45	GO:0060972	left/right pattern formation

0.51	GO:0003713	transcription coactivator activity
0.49	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.47	GO:0001104	RNA polymerase II transcription cofactor activity
0.43	GO:0001102	RNA polymerase II activating transcription factor binding
0.43	GO:0046332	SMAD binding
0.42	GO:0003682	chromatin binding
0.38	GO:0003700	DNA binding transcription factor activity
0.36	GO:0050693	LBD domain binding
0.36	GO:0003714	transcription corepressor activity
0.35	GO:0035035	histone acetyltransferase binding

0.61	GO:0005634	nucleus
0.40	GO:0000785	chromatin
0.39	GO:0070013	intracellular organelle lumen
0.36	GO:0005737	cytoplasm
0.33	GO:0043234	protein complex

0.32

EC:5

GO:0016853

sp|Q9I8P6|OTOR_CHICK
Otoraplin
Search

OTOR

0.97

Otoraplin

0.81	GO:0001502	cartilage condensation
0.38	GO:0007605	sensory perception of sound
0.37	GO:0007018	microtubule-based movement

0.37

GO:0003777

microtubule motor activity

0.42	GO:0005576	extracellular region
0.38	GO:0030286	dynein complex
0.37	GO:0005794	Golgi apparatus
0.30	GO:0044425	membrane part

sp|Q9I8Q3|CFC1_CHICK
Cryptic protein
Search

0.97	Teratocarcinoma-derived growth factor 1

0.70	GO:0090008	hypoblast development
0.70	GO:0072045	convergent extension involved in nephron morphogenesis
0.69	GO:0021501	prechordal plate formation
0.68	GO:0035775	pronephric glomerulus morphogenesis
0.68	GO:0046619	optic placode formation involved in camera-type eye formation
0.68	GO:0007369	gastrulation
0.68	GO:0021999	neural plate anterior/posterior regionalization
0.68	GO:0003260	cardioblast migration
0.68	GO:0021508	floor plate formation
0.67	GO:0003318	cell migration to the midline involved in heart development

0.42	GO:0005509	calcium ion binding
0.35	GO:0008270	zinc ion binding

0.61	GO:0009897	external side of plasma membrane
0.51	GO:0031225	anchored component of membrane
0.45	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|Q9I8T7|BMAL1_CHICK
Aryl hydrocarbon receptor nuclear translocator-like protein 1
Search

ARNTL

0.91	Aryl hydrocarbon receptor nuclear translocator like

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:0090403	oxidative stress-induced premature senescence
0.57	GO:2001016	positive regulation of skeletal muscle cell differentiation
0.57	GO:2000074	regulation of type B pancreatic cell development
0.56	GO:0010468	regulation of gene expression
0.56	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway
0.56	GO:0060137	maternal process involved in parturition
0.55	GO:0042634	regulation of hair cycle

0.68	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0017162	aryl hydrocarbon receptor binding
0.55	GO:0070888	E-box binding
0.54	GO:0043425	bHLH transcription factor binding
0.54	GO:0051879	Hsp90 protein binding
0.53	GO:0070491	repressing transcription factor binding
0.53	GO:0001047	core promoter binding
0.53	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.37	GO:0003682	chromatin binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.56	GO:0033391	chromatoid body
0.46	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.36	GO:0005694	chromosome
0.33	GO:0005829	cytosol

sp|Q9I8W6|EURL_CHICK
Protein EURL
Search

0.86	GO:0021895	cerebral cortex neuron differentiation
0.86	GO:0060999	positive regulation of dendritic spine development

0.36

GO:0005515

protein binding

sp|Q9I920|BLM_CHICK
Bloom syndrome protein homolog (Fragment)
Search

BLM

0.42	Bloom syndrome RecQ like helicase

0.69	GO:0032508	DNA duplex unwinding
0.66	GO:0006260	DNA replication
0.65	GO:0006310	DNA recombination
0.64	GO:0006281	DNA repair
0.57	GO:0072757	cellular response to camptothecin
0.57	GO:0035786	protein complex oligomerization
0.56	GO:0061820	telomeric D-loop disassembly
0.56	GO:0072711	cellular response to hydroxyurea
0.56	GO:0044806	G-quadruplex DNA unwinding
0.55	GO:0045910	negative regulation of DNA recombination

0.79	GO:0043140	ATP-dependent 3'-5' DNA helicase activity
0.59	GO:0061749	forked DNA-dependent helicase activity
0.57	GO:1905773	8-hydroxy-2'-deoxyguanosine DNA binding
0.57	GO:0061821	telomeric D-loop binding
0.56	GO:0000405	bubble DNA binding
0.55	GO:0000400	four-way junction DNA binding
0.55	GO:0051880	G-quadruplex DNA binding
0.55	GO:0036310	annealing helicase activity
0.55	GO:0000403	Y-form DNA binding
0.55	GO:0030554	adenyl nucleotide binding

0.60	GO:0005634	nucleus
0.51	GO:0000781	chromosome, telomeric region
0.50	GO:0000793	condensed chromosome
0.46	GO:0005829	cytosol
0.46	GO:0070013	intracellular organelle lumen
0.36	GO:0005657	replication fork
0.30	GO:0016020	membrane

0.33

GO:0008234

sp|Q9I923|RGN_CHICK
Regucalcin
Search

RGN

0.83	Epididymis secretory protein Li 41

0.68	GO:0050790	regulation of catalytic activity
0.59	GO:0019853	L-ascorbic acid biosynthetic process
0.44	GO:0050848	regulation of calcium-mediated signaling
0.43	GO:0006874	cellular calcium ion homeostasis
0.41	GO:0044093	positive regulation of molecular function
0.40	GO:1903625	negative regulation of DNA catabolic process
0.40	GO:1901318	negative regulation of flagellated sperm motility
0.40	GO:1903011	negative regulation of bone development
0.39	GO:0045019	negative regulation of nitric oxide biosynthetic process
0.39	GO:0010867	positive regulation of triglyceride biosynthetic process

0.70	GO:0030234	enzyme regulator activity
0.70	GO:0005509	calcium ion binding
0.59	GO:0004341	gluconolactonase activity
0.46	GO:0008270	zinc ion binding
0.35	GO:0008081	phosphoric diester hydrolase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.45	GO:0005634	nucleus
0.42	GO:0005576	extracellular region
0.39	GO:0005737	cytoplasm

0.59

EC:3.1.1.17

GO:0004341

sp|Q9I946|PDGFC_CHICK
Platelet-derived growth factor C
Search

PDGFC

0.97	Platelet-derived growth factor C

0.85	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.75	GO:0008284	positive regulation of cell proliferation
0.74	GO:0010469	regulation of receptor activity
0.73	GO:0009790	embryo development
0.58	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity
0.58	GO:0048145	regulation of fibroblast proliferation
0.58	GO:0071230	cellular response to amino acid stimulus
0.57	GO:0045740	positive regulation of DNA replication
0.56	GO:0050730	regulation of peptidyl-tyrosine phosphorylation
0.54	GO:0060348	bone development

0.86	GO:0005161	platelet-derived growth factor receptor binding
0.77	GO:0008083	growth factor activity
0.52	GO:0042803	protein homodimerization activity

0.54	GO:0005615	extracellular space
0.52	GO:0009986	cell surface
0.49	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.38	GO:1903561	extracellular vesicle
0.36	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0005634	nucleus
0.35	GO:0000139	Golgi membrane

tr|Q9I950|Q9I950_CHICK
Fibroblast growth factor
Search

FGF18

0.61	Fibroblast growth factor

0.84	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.58	GO:1904849	positive regulation of cell chemotaxis to fibroblast growth factor
0.57	GO:0001957	intramembranous ossification
0.57	GO:2000544	regulation of endothelial cell chemotaxis to fibroblast growth factor
0.57	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
0.56	GO:2001028	positive regulation of endothelial cell chemotaxis
0.56	GO:0032332	positive regulation of chondrocyte differentiation
0.56	GO:0001958	endochondral ossification
0.56	GO:0002063	chondrocyte development

0.85	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0004713	protein tyrosine kinase activity
0.33	GO:0004984	olfactory receptor activity
0.33	GO:0004930	G-protein coupled receptor activity
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.49	GO:0005730	nucleolus
0.32	GO:0005737	cytoplasm
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|Q9I969|TXLNB_CHICK
Beta-taxilin
Search

TXLNB

0.90	Taxilin alpha

0.49	GO:0042113	B cell activation
0.38	GO:0010976	positive regulation of neuron projection development
0.35	GO:0006887	exocytosis
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0080090	regulation of primary metabolic process
0.34	GO:0010468	regulation of gene expression
0.34	GO:0051171	regulation of nitrogen compound metabolic process
0.34	GO:0006606	protein import into nucleus
0.33	GO:0001731	formation of translation preinitiation complex
0.33	GO:0008283	cell proliferation

0.84	GO:0019905	syntaxin binding
0.35	GO:0030372	high molecular weight B cell growth factor receptor binding
0.34	GO:0061608	nuclear import signal receptor activity
0.34	GO:0005125	cytokine activity
0.33	GO:0003743	translation initiation factor activity
0.33	GO:0008565	protein transporter activity
0.32	GO:0003677	DNA binding

0.41	GO:0005737	cytoplasm
0.38	GO:0099512	supramolecular fiber
0.37	GO:0005615	extracellular space
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0044422	organelle part
0.34	GO:0005634	nucleus
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q9I993|BCDO1_CHICK
Beta,beta-carotene 15,15'-dioxygenase
Search

BCO1

0.70	Beta-carotene oxygenase 1

0.59	GO:1901810	beta-carotene metabolic process
0.57	GO:0042574	retinal metabolic process
0.53	GO:0055114	oxidation-reduction process
0.42	GO:0001754	eye photoreceptor cell differentiation
0.42	GO:0030902	hindbrain development
0.39	GO:0042572	retinol metabolic process
0.38	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.35	GO:0035238	vitamin A biosynthetic process
0.35	GO:0032526	response to retinoic acid
0.34	GO:0016122	xanthophyll metabolic process

0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.57	GO:0004497	monooxygenase activity
0.54	GO:0046872	metal ion binding

0.34	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol

0.75

EC:1.13.11

GO:0016702

sp|Q9I9E0|TAOK3_CHICK
Serine/threonine-protein kinase TAO3
Search

TAOK3

0.90	Serine/threonine-protein kinase TAO3

0.65	GO:0007095	mitotic G2 DNA damage checkpoint
0.63	GO:0032874	positive regulation of stress-activated MAPK cascade
0.62	GO:0006468	protein phosphorylation
0.62	GO:0046328	regulation of JNK cascade
0.59	GO:0043406	positive regulation of MAP kinase activity
0.58	GO:0032873	negative regulation of stress-activated MAPK cascade
0.53	GO:0097194	execution phase of apoptosis
0.51	GO:0031098	stress-activated protein kinase signaling cascade
0.50	GO:0032147	activation of protein kinase activity
0.48	GO:0042981	regulation of apoptotic process

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0005057	signal transducer activity, downstream of receptor
0.37	GO:0019887	protein kinase regulator activity
0.36	GO:0019209	kinase activator activity
0.35	GO:0005515	protein binding
0.35	GO:0019210	kinase inhibitor activity

0.39	GO:0005622	intracellular
0.35	GO:0070062	extracellular exosome
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q9I9G9|Q9I9G9_CHICK
Beta-synuclein
Search

SNCB

0.91	Gamma-synuclein

0.72	GO:0014059	regulation of dopamine secretion
0.62	GO:0042417	dopamine metabolic process
0.60	GO:0043524	negative regulation of neuron apoptotic process
0.58	GO:0050808	synapse organization
0.56	GO:0007268	chemical synaptic transmission
0.52	GO:0051945	negative regulation of catecholamine uptake involved in synaptic transmission
0.52	GO:0051621	regulation of norepinephrine uptake
0.52	GO:1903284	positive regulation of glutathione peroxidase activity
0.52	GO:1903285	positive regulation of hydrogen peroxide catabolic process
0.52	GO:1904715	negative regulation of chaperone-mediated autophagy

0.63	GO:1903136	cuprous ion binding
0.52	GO:0005509	calcium ion binding
0.51	GO:0048156	tau protein binding
0.51	GO:0050544	arachidonic acid binding
0.50	GO:0043014	alpha-tubulin binding
0.50	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.50	GO:0030544	Hsp70 protein binding
0.49	GO:0019894	kinesin binding
0.48	GO:0070840	dynein complex binding
0.48	GO:0051219	phosphoprotein binding

0.60	GO:0016234	inclusion body
0.57	GO:0045202	synapse
0.51	GO:0031092	platelet alpha granule membrane
0.49	GO:0030426	growth cone
0.48	GO:0043025	neuronal cell body
0.48	GO:0030424	axon
0.47	GO:0005739	mitochondrion
0.47	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0005615	extracellular space
0.46	GO:0005938	cell cortex

0.38

GO:0016491

tr|Q9I9H0|Q9I9H0_CHICK
Gamma-synuclein
Search

SNCG

0.97	Gamma-synuclein

0.71	GO:0014059	regulation of dopamine secretion
0.70	GO:0050808	synapse organization
0.67	GO:0007268	chemical synaptic transmission
0.66	GO:0046928	regulation of neurotransmitter secretion
0.65	GO:0008344	adult locomotory behavior
0.56	GO:0042417	dopamine metabolic process
0.55	GO:0009306	protein secretion
0.54	GO:0043524	negative regulation of neuron apoptotic process
0.37	GO:0071464	cellular response to hydrostatic pressure
0.37	GO:0002118	aggressive behavior

0.57	GO:1903136	cuprous ion binding
0.48	GO:0005509	calcium ion binding
0.38	GO:0043014	alpha-tubulin binding
0.38	GO:0048487	beta-tubulin binding
0.36	GO:0004859	phospholipase inhibitor activity

0.63	GO:0043025	neuronal cell body
0.62	GO:0030424	axon
0.54	GO:0016234	inclusion body
0.51	GO:0045202	synapse
0.48	GO:0005737	cytoplasm
0.42	GO:0043227	membrane-bounded organelle
0.42	GO:0005819	spindle
0.42	GO:0005815	microtubule organizing center
0.38	GO:0043230	extracellular organelle
0.38	GO:0044306	neuron projection terminus

sp|Q9I9J6|SMAP_CHICK
Small acidic protein
Search

SMAP

0.97	small acidic protein isoform X2

sp|Q9I9K9|GATM_CHICK
Glycine amidinotransferase, mitochondrial
Search

GATM

0.87	LOW QUALITY PROTEIN: glycine amidinotransferase, mitochondrial

0.65	GO:0006601	creatine biosynthetic process
0.62	GO:0014889	muscle atrophy
0.57	GO:0007611	learning or memory
0.51	GO:0007275	multicellular organism development
0.35	GO:0042246	tissue regeneration
0.35	GO:0007584	response to nutrient
0.35	GO:0043434	response to peptide hormone
0.35	GO:0046689	response to mercury ion
0.34	GO:0006979	response to oxidative stress

0.84

GO:0015067

amidinotransferase activity

0.56	GO:0005758	mitochondrial intermembrane space
0.40	GO:0031966	mitochondrial membrane
0.40	GO:0019866	organelle inner membrane
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:2.1.4

GO:0015067

sp|Q9I9R0|HABP4_CHICK
Intracellular hyaluronan-binding protein 4
Search

HABP4

0.96	Intracellular hyaluronan-binding protein 4

0.84	GO:0033120	positive regulation of RNA splicing
0.83	GO:0043392	negative regulation of DNA binding
0.80	GO:0045948	positive regulation of translational initiation
0.54	GO:0071260	cellular response to mechanical stimulus
0.50	GO:0008380	RNA splicing
0.49	GO:0006397	mRNA processing
0.43	GO:0006351	transcription, DNA-templated
0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:0002576	platelet degranulation
0.40	GO:0030212	hyaluronan metabolic process

0.47	GO:0003730	mRNA 3'-UTR binding
0.40	GO:0005540	hyaluronic acid binding
0.38	GO:0005515	protein binding
0.36	GO:0019205	nucleobase-containing compound kinase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.85	GO:0097504	Gemini of coiled bodies
0.83	GO:0015030	Cajal body
0.78	GO:0010494	cytoplasmic stress granule
0.77	GO:0016607	nuclear speck
0.71	GO:0005730	nucleolus
0.56	GO:0016528	sarcoplasm
0.52	GO:0030017	sarcomere
0.37	GO:0005829	cytosol
0.37	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q9IA02|FZD9_CHICK
Frizzled-9 (Fragment)
Search

FZD9

0.97	Frizzled class receptor 9

0.72	GO:0016055	Wnt signaling pathway
0.67	GO:0007275	multicellular organism development
0.55	GO:1904394	negative regulation of skeletal muscle acetylcholine-gated channel clustering
0.54	GO:1990523	bone regeneration
0.52	GO:0071157	negative regulation of cell cycle arrest
0.52	GO:2000179	positive regulation of neural precursor cell proliferation
0.51	GO:0030501	positive regulation of bone mineralization
0.51	GO:0043524	negative regulation of neuron apoptotic process
0.51	GO:0072089	stem cell proliferation
0.50	GO:0061351	neural precursor cell proliferation

0.70	GO:0004888	transmembrane signaling receptor activity
0.57	GO:0017147	Wnt-protein binding
0.47	GO:0042803	protein homodimerization activity
0.47	GO:0046982	protein heterodimerization activity
0.32	GO:0003677	DNA binding

0.52	GO:0031527	filopodium membrane
0.50	GO:0009986	cell surface
0.48	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005654	nucleoplasm
0.35	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0005794	Golgi apparatus
0.34	GO:0031966	mitochondrial membrane
0.33	GO:0005887	integral component of plasma membrane

sp|Q9IA03|FZD8_CHICK
Frizzled-8 (Fragment)
Search

0.10	Frizzled-8

0.71	GO:0007166	cell surface receptor signaling pathway
0.70	GO:0198738	cell-cell signaling by wnt
0.68	GO:0007275	multicellular organism development
0.54	GO:0060061	Spemann organizer formation
0.53	GO:0002726	positive regulation of T cell cytokine production
0.53	GO:0043507	positive regulation of JUN kinase activity
0.53	GO:1901382	regulation of chorionic trophoblast cell proliferation
0.53	GO:0060718	chorionic trophoblast cell differentiation
0.52	GO:1903146	regulation of autophagy of mitochondrion
0.52	GO:0032729	positive regulation of interferon-gamma production

0.70	GO:0004888	transmembrane signaling receptor activity
0.61	GO:0017147	Wnt-protein binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0001540	amyloid-beta binding
0.49	GO:0019901	protein kinase binding
0.44	GO:0030165	PDZ domain binding
0.39	GO:0005102	receptor binding

0.54	GO:0106003	amyloid-beta complex
0.49	GO:0005923	bicellular tight junction
0.48	GO:0005769	early endosome
0.48	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0009986	cell surface
0.46	GO:0005794	Golgi apparatus
0.44	GO:0044459	plasma membrane part
0.37	GO:0098796	membrane protein complex
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0031984	organelle subcompartment

sp|Q9IA05|FZD4_CHICK
Frizzled-4
Search

FZD4

0.80	Frizzled class receptor 4

0.76	GO:0016055	Wnt signaling pathway
0.66	GO:0007275	multicellular organism development
0.60	GO:0035929	steroid hormone secretion
0.60	GO:0035426	extracellular matrix-cell signaling
0.60	GO:0031987	locomotion involved in locomotory behavior
0.58	GO:0010812	negative regulation of cell-substrate adhesion
0.58	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway
0.57	GO:0034446	substrate adhesion-dependent cell spreading
0.57	GO:0043507	positive regulation of JUN kinase activity
0.56	GO:0022602	ovulation cycle process

0.84	GO:0042813	Wnt-activated receptor activity
0.58	GO:0017147	Wnt-protein binding
0.57	GO:0001540	amyloid-beta binding
0.57	GO:0030165	PDZ domain binding
0.57	GO:0019955	cytokine binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0042803	protein homodimerization activity
0.52	GO:0046982	protein heterodimerization activity
0.44	GO:0004930	G-protein coupled receptor activity

0.59	GO:0106003	amyloid-beta complex
0.54	GO:0030425	dendrite
0.52	GO:0009986	cell surface
0.52	GO:0005911	cell-cell junction
0.43	GO:0005886	plasma membrane
0.39	GO:0070062	extracellular exosome
0.35	GO:0030669	clathrin-coated endocytic vesicle membrane
0.30	GO:0016021	integral component of membrane

sp|Q9IA06|FZD2_CHICK
Frizzled-2 (Fragment)
Search

FZD2

0.89	Frizzled class receptor 2

0.77	GO:0016055	Wnt signaling pathway
0.69	GO:0007275	multicellular organism development
0.59	GO:0045995	regulation of embryonic development
0.59	GO:0060429	epithelium development
0.57	GO:0060022	hard palate development
0.56	GO:0010562	positive regulation of phosphorus metabolic process
0.56	GO:1905276	regulation of epithelial tube formation
0.56	GO:0009653	anatomical structure morphogenesis
0.55	GO:0090175	regulation of establishment of planar polarity
0.54	GO:0045893	positive regulation of transcription, DNA-templated

0.85	GO:0042813	Wnt-activated receptor activity
0.61	GO:0030165	PDZ domain binding
0.60	GO:0017147	Wnt-protein binding
0.53	GO:0005109	frizzled binding
0.49	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.48	GO:0004930	G-protein coupled receptor activity
0.35	GO:0046982	protein heterodimerization activity
0.35	GO:0042802	identical protein binding
0.35	GO:0045545	syndecan binding
0.33	GO:0004672	protein kinase activity

0.49	GO:0055038	recycling endosome membrane
0.45	GO:0005886	plasma membrane
0.40	GO:0009986	cell surface
0.38	GO:0005925	focal adhesion
0.35	GO:1990909	Wnt signalosome
0.35	GO:0030669	clathrin-coated endocytic vesicle membrane
0.34	GO:0043005	neuron projection
0.30	GO:0016021	integral component of membrane

sp|Q9IA31|GLI3_CHICK
Transcriptional activator GLI3 (Fragment)
Search

GLI3

0.77	GLI family zinc finger 3

0.82	GO:0009953	dorsal/ventral pattern formation
0.82	GO:0007224	smoothened signaling pathway
0.80	GO:0009952	anterior/posterior pattern specification
0.79	GO:0048568	embryonic organ development
0.74	GO:0022018	lateral ganglionic eminence cell proliferation
0.74	GO:0060873	anterior semicircular canal development
0.74	GO:0060366	lambdoid suture morphogenesis
0.74	GO:0060367	sagittal suture morphogenesis
0.74	GO:0060875	lateral semicircular canal development
0.74	GO:0060364	frontal suture morphogenesis

0.72	GO:0035035	histone acetyltransferase binding
0.69	GO:0042826	histone deacetylase binding
0.68	GO:0008013	beta-catenin binding
0.68	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.64	GO:0003682	chromatin binding
0.60	GO:0003700	DNA binding transcription factor activity
0.41	GO:0008134	transcription factor binding
0.39	GO:0008270	zinc ion binding

0.67	GO:0005930	axoneme
0.66	GO:0016607	nuclear speck
0.64	GO:0017053	transcriptional repressor complex
0.63	GO:0016592	mediator complex
0.57	GO:0005829	cytosol
0.45	GO:0097542	ciliary tip
0.43	GO:0031514	motile cilium
0.41	GO:0005730	nucleolus
0.36	GO:0097730	non-motile cilium
0.30	GO:0016020	membrane

sp|Q9IA88|SIK2_CHICK
Serine/threonine-protein kinase SIK2
Search

SIK1

0.80	Serine/threonine-protein kinase SIK2

0.63	GO:0006468	protein phosphorylation
0.44	GO:0035556	intracellular signal transduction
0.39	GO:0046626	regulation of insulin receptor signaling pathway
0.37	GO:0032870	cellular response to hormone stimulus

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0000287	magnesium ion binding

0.36	GO:0005622	intracellular
0.34	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q9IA95|SFRP3_CHICK
Secreted frizzled-related protein 3
Search

FRZB

0.96	LOW QUALITY PROTEIN: secreted frizzled-related protein 3

0.71	GO:0016055	Wnt signaling pathway
0.67	GO:0007275	multicellular organism development
0.61	GO:0070367	negative regulation of hepatocyte differentiation
0.59	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.57	GO:0061037	negative regulation of cartilage development
0.56	GO:0045600	positive regulation of fat cell differentiation
0.56	GO:0060026	convergent extension
0.56	GO:0008285	negative regulation of cell proliferation
0.55	GO:0043065	positive regulation of apoptotic process
0.55	GO:0030308	negative regulation of cell growth

0.62	GO:0017147	Wnt-protein binding
0.50	GO:0042813	Wnt-activated receptor activity
0.45	GO:0004930	G-protein coupled receptor activity

0.66	GO:0005576	extracellular region
0.42	GO:0009986	cell surface
0.38	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q9IA96|SFRP2_CHICK
Secreted frizzled-related protein 2
Search

SFRP2

0.97	Secreted frizzled-related protein 2

0.71	GO:0016055	Wnt signaling pathway
0.66	GO:0007275	multicellular organism development
0.63	GO:0061185	negative regulation of dermatome development
0.62	GO:2000041	negative regulation of planar cell polarity pathway involved in axis elongation
0.61	GO:0042662	negative regulation of mesodermal cell fate specification
0.61	GO:0071481	cellular response to X-ray
0.61	GO:2000035	regulation of stem cell division
0.60	GO:0035413	positive regulation of catenin import into nucleus
0.60	GO:0043508	negative regulation of JUN kinase activity
0.60	GO:0010667	negative regulation of cardiac muscle cell apoptotic process

0.61	GO:0017147	Wnt-protein binding
0.59	GO:0061133	endopeptidase activator activity
0.53	GO:0048018	receptor ligand activity
0.50	GO:0042813	Wnt-activated receptor activity
0.45	GO:0004930	G-protein coupled receptor activity
0.38	GO:0001968	fibronectin binding
0.37	GO:0005178	integrin binding

0.63	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|Q9IAD2|Q9IAD2_CHICK
P2X purinoceptor
Search

sp|Q9IAK4|NOE1_CHICK
Noelin
Search

OLFM1

0.95	Olfactomedin 1

0.74	GO:0007399	nervous system development
0.51	GO:0003190	atrioventricular valve formation
0.50	GO:0060317	cardiac epithelial to mesenchymal transition
0.49	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.44	GO:0010628	positive regulation of gene expression
0.43	GO:0010629	negative regulation of gene expression
0.40	GO:0023041	neuronal signal transduction
0.39	GO:0061387	regulation of extent of cell growth
0.38	GO:0010769	regulation of cell morphogenesis involved in differentiation
0.38	GO:0048638	regulation of developmental growth

0.37	GO:0001540	amyloid-beta binding
0.34	GO:0005515	protein binding

0.39	GO:0044295	axonal growth cone
0.39	GO:0043204	perikaryon
0.37	GO:0045202	synapse
0.37	GO:0030054	cell junction
0.37	GO:0005615	extracellular space
0.37	GO:0032281	AMPA glutamate receptor complex
0.37	GO:0005783	endoplasmic reticulum
0.35	GO:0098590	plasma membrane region

sp|Q9IAL1|VSX2_CHICK
Visual system homeobox 2
Search

VSX2

0.92	Visual system homeobox 2

0.63	GO:0007275	multicellular organism development
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.42	GO:0007601	visual perception
0.37	GO:0030154	cell differentiation
0.37	GO:0009653	anatomical structure morphogenesis
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:0050896	response to stimulus
0.36	GO:0048523	negative regulation of cellular process

0.63	GO:0043565	sequence-specific DNA binding
0.37	GO:0003682	chromatin binding
0.36	GO:0044212	transcription regulatory region DNA binding
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm

sp|Q9IAL2|VSX1_CHICK
Visual system homeobox 1
Search

0.89	Visual system homeobox 1

0.57	GO:0007275	multicellular organism development
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.41	GO:0007601	visual perception
0.40	GO:0030154	cell differentiation
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:0048328	regulation of axial mesodermal cell fate specification
0.37	GO:0009653	anatomical structure morphogenesis
0.36	GO:0042662	negative regulation of mesodermal cell fate specification

0.62	GO:0043565	sequence-specific DNA binding
0.40	GO:0003682	chromatin binding
0.39	GO:0044212	transcription regulatory region DNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm

sp|Q9IAL7|NCKX2_CHICK
Sodium/potassium/calcium exchanger 2
Search

SLC24A2

0.96	Sodium/potassium/calcium exchanger 2

0.74	GO:0007601	visual perception
0.73	GO:0035725	sodium ion transmembrane transport
0.58	GO:0060292	long term synaptic depression
0.56	GO:0060291	long-term synaptic potentiation
0.53	GO:0007613	memory
0.53	GO:0006874	cellular calcium ion homeostasis
0.53	GO:0007612	learning
0.52	GO:0070588	calcium ion transmembrane transport
0.36	GO:0006813	potassium ion transport
0.34	GO:0050896	response to stimulus

0.82	GO:0008273	calcium, potassium:sodium antiporter activity
0.53	GO:0005262	calcium channel activity
0.45	GO:0031402	sodium ion binding
0.44	GO:0030955	potassium ion binding
0.42	GO:0005509	calcium ion binding
0.37	GO:0015293	symporter activity
0.36	GO:0046870	cadmium ion binding
0.35	GO:0016151	nickel cation binding
0.35	GO:0030145	manganese ion binding
0.34	GO:0046983	protein dimerization activity

0.41

GO:0005887

integral component of plasma membrane

sp|Q9IAL8|NCKX1_CHICK
Sodium/potassium/calcium exchanger 1
Search

SLC24A2

0.90	Sodium/potassium/calcium exchanger 1

0.59	GO:0007601	visual perception
0.58	GO:0035725	sodium ion transmembrane transport
0.44	GO:0060292	long term synaptic depression
0.44	GO:0060291	long-term synaptic potentiation
0.43	GO:0006816	calcium ion transport
0.42	GO:0006874	cellular calcium ion homeostasis
0.39	GO:0007613	memory
0.39	GO:0007612	learning
0.39	GO:0006813	potassium ion transport
0.36	GO:0050896	response to stimulus

0.64	GO:0008273	calcium, potassium:sodium antiporter activity
0.42	GO:0005262	calcium channel activity
0.41	GO:0031402	sodium ion binding
0.40	GO:0030955	potassium ion binding
0.39	GO:0015293	symporter activity
0.39	GO:0046870	cadmium ion binding
0.39	GO:0005509	calcium ion binding
0.36	GO:0016151	nickel cation binding
0.36	GO:0030145	manganese ion binding
0.36	GO:0046983	protein dimerization activity

0.38

GO:0005887

integral component of plasma membrane

sp|Q9IAM7|MRE11_CHICK
Double-strand break repair protein MRE11
Search

MRE11

0.89	Double-strand break repair protein MRE11

0.73	GO:0051321	meiotic cell cycle
0.73	GO:0006302	double-strand break repair
0.62	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.59	GO:0031860	telomeric 3' overhang formation
0.58	GO:0032876	negative regulation of DNA endoreduplication
0.58	GO:0031954	positive regulation of protein autophosphorylation
0.57	GO:0031573	intra-S DNA damage checkpoint
0.56	GO:0032206	positive regulation of telomere maintenance
0.56	GO:0007095	mitotic G2 DNA damage checkpoint
0.54	GO:0000726	non-recombinational repair

0.70	GO:0030145	manganese ion binding
0.69	GO:0008408	3'-5' exonuclease activity
0.64	GO:0004519	endonuclease activity
0.55	GO:0008022	protein C-terminus binding
0.54	GO:0045296	cadherin binding
0.51	GO:0042802	identical protein binding
0.50	GO:0004003	ATP-dependent DNA helicase activity
0.49	GO:0004536	deoxyribonuclease activity
0.42	GO:0003677	DNA binding

0.80	GO:0030870	Mre11 complex
0.56	GO:0016605	PML body
0.55	GO:0035861	site of double-strand break
0.54	GO:0000784	nuclear chromosome, telomeric region
0.39	GO:0005737	cytoplasm
0.34	GO:0000794	condensed nuclear chromosome
0.34	GO:0000790	nuclear chromatin

tr|Q9IAR7|Q9IAR7_CHICK
TvbS1
Search

TNFRSF10B

0.95	Subgroup E ALV receptor

0.61	GO:0007165	signal transduction
0.45	GO:0071356	cellular response to tumor necrosis factor
0.45	GO:0032496	response to lipopolysaccharide
0.44	GO:0006954	inflammatory response
0.44	GO:0006915	apoptotic process
0.43	GO:0042127	regulation of cell proliferation
0.43	GO:0042981	regulation of apoptotic process
0.43	GO:0006955	immune response
0.41	GO:0007275	multicellular organism development

0.63	GO:0045569	TRAIL binding
0.47	GO:0005031	tumor necrosis factor-activated receptor activity

0.41

GO:0005887

integral component of plasma membrane

sp|Q9IAX2|IOD2_CHICK
Type II iodothyronine deiodinase
Search

DIO2

0.69	Type II iodothyronine deiodinase

0.79	GO:0042446	hormone biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0042403	thyroid hormone metabolic process
0.42	GO:0061074	regulation of neural retina development
0.42	GO:0019336	phenol-containing compound catabolic process
0.42	GO:0042447	hormone catabolic process
0.41	GO:0048066	developmental pigmentation
0.41	GO:0042219	cellular modified amino acid catabolic process
0.40	GO:0048589	developmental growth
0.40	GO:0043009	chordate embryonic development

0.86	GO:0004800	thyroxine 5'-deiodinase activity
0.39	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0008430	selenium binding

0.33	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.86

EC:1.97.1.10

GO:0004800

sp|Q9IAY5|SDOS_CHICK
Protein syndesmos
Search

NUDT16L1

0.92	Tudor-interacting repair regulator protein (Fragment)

0.57	GO:2000779	regulation of double-strand break repair
0.53	GO:0045738	negative regulation of DNA repair
0.50	GO:1901639	XDP catabolic process
0.49	GO:0046709	IDP catabolic process
0.48	GO:0016077	snoRNA catabolic process
0.46	GO:0045739	positive regulation of DNA repair
0.45	GO:0090068	positive regulation of cell cycle process
0.45	GO:0006382	adenosine to inosine editing
0.44	GO:0008284	positive regulation of cell proliferation
0.43	GO:0006402	mRNA catabolic process

0.56	GO:0030515	snoRNA binding
0.52	GO:0050072	m7G(5')pppN diphosphatase activity
0.50	GO:1901640	XTP binding
0.50	GO:1901641	ITP binding
0.47	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides
0.46	GO:0042803	protein homodimerization activity
0.44	GO:0050897	cobalt ion binding
0.43	GO:0003729	mRNA binding
0.43	GO:0008235	metalloexopeptidase activity
0.43	GO:0030145	manganese ion binding

0.46	GO:0005634	nucleus
0.41	GO:0031974	membrane-enclosed lumen
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.38	GO:0044446	intracellular organelle part
0.37	GO:0005925	focal adhesion
0.36	GO:0005737	cytoplasm
0.33	GO:0005886	plasma membrane

0.52	EC:3.6.1.30	GO:0050072
0.42	KEGG:R03531	GO:0035870

tr|Q9IB15|Q9IB15_CHICK
PBX1A
Search

PBX1

0.94	Pre-B-cell leukemia transcription factor 1

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.54	GO:0030325	adrenal gland development
0.54	GO:0048536	spleen development
0.53	GO:0001658	branching involved in ureteric bud morphogenesis
0.53	GO:0009954	proximal/distal pattern formation
0.53	GO:0048538	thymus development
0.53	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
0.53	GO:0035162	embryonic hemopoiesis

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0046982	protein heterodimerization activity
0.48	GO:0003690	double-stranded DNA binding
0.38	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.50	GO:0005667	transcription factor complex
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.38	GO:0005737	cytoplasm
0.34	GO:0030496	midbody
0.30	GO:0016020	membrane

tr|Q9IBC9|Q9IBC9_CHICK
Tetraspanin
Search

CD9

0.59	Tetraspanin

0.54	GO:0090331	negative regulation of platelet aggregation
0.53	GO:0030913	paranodal junction assembly
0.53	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization
0.53	GO:0071404	cellular response to low-density lipoprotein particle stimulus
0.51	GO:0031623	receptor internalization
0.51	GO:0051271	negative regulation of cellular component movement
0.49	GO:0008285	negative regulation of cell proliferation
0.47	GO:0007155	cell adhesion
0.40	GO:0007166	cell surface receptor signaling pathway
0.35	GO:0048916	posterior lateral line development

0.50	GO:0070062	extracellular exosome
0.49	GO:0009897	external side of plasma membrane
0.39	GO:0005887	integral component of plasma membrane

sp|Q9PRL8|ACBP_CHICK
Acyl-CoA-binding protein
Search

DBI

0.61	Benzodiazepine receptor ligand

0.49	GO:0036151	phosphatidylcholine acyl-chain remodeling
0.36	GO:0021670	lateral ventricle development
0.36	GO:0001662	behavioral fear response
0.36	GO:0032228	regulation of synaptic transmission, GABAergic
0.36	GO:0060291	long-term synaptic potentiation
0.36	GO:0001942	hair follicle development
0.36	GO:0018345	protein palmitoylation
0.36	GO:0001300	chronological cell aging
0.36	GO:0042761	very long-chain fatty acid biosynthetic process
0.36	GO:0007611	learning or memory

0.82	GO:0000062	fatty-acyl-CoA binding
0.41	GO:0046983	protein dimerization activity
0.40	GO:0008289	lipid binding
0.36	GO:0030156	benzodiazepine receptor binding
0.33	GO:0008483	transaminase activity
0.33	GO:0030170	pyridoxal phosphate binding
0.32	GO:0016787	hydrolase activity

0.39	GO:0005794	Golgi apparatus
0.39	GO:0005783	endoplasmic reticulum
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005576	extracellular region
0.36	GO:0008021	synaptic vesicle
0.34	GO:0043292	contractile fiber
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005739	mitochondrion
0.33	GO:0043209	myelin sheath
0.33	GO:0043233	organelle lumen

0.33

EC:2.6.1

GO:0008483

sp|Q9PRP6|MOTI_CHICK
Motilin
Search

0.73

Motilin

0.75	GO:0010469	regulation of receptor activity
0.60	GO:0006939	smooth muscle contraction

0.79

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

sp|Q9PRS8|OC17_CHICK
Ovocleidin-17
Search

0.92	Ovocleidin-17

0.70	GO:0031215	shell calcification
0.63	GO:0019731	antibacterial humoral response
0.54	GO:0030574	collagen catabolic process
0.40	GO:0007165	signal transduction

0.82	GO:1990430	extracellular matrix protein binding
0.63	GO:0003823	antigen binding
0.63	GO:0030246	carbohydrate binding
0.61	GO:0001530	lipopolysaccharide binding
0.58	GO:0042834	peptidoglycan binding
0.53	GO:0005509	calcium ion binding
0.52	GO:0005518	collagen binding
0.43	GO:0099600	transmembrane receptor activity
0.42	GO:0038023	signaling receptor activity

0.57	GO:0005578	proteinaceous extracellular matrix
0.55	GO:0005615	extracellular space
0.42	GO:0005887	integral component of plasma membrane

sp|Q9PSW9|H2B8_CHICK
Histone H2B 8
Search

sp|Q9PSX7|RHOC_CHICK
Rho-related GTP-binding protein RhoC
Search

RHOC

0.89	Rho-related GTP-binding protein RhoC

0.78	GO:1902766	skeletal muscle satellite cell migration
0.77	GO:0007264	small GTPase mediated signal transduction
0.76	GO:0090505	epiboly involved in wound healing
0.54	GO:0032464	positive regulation of protein homooligomerization
0.52	GO:0043297	apical junction assembly
0.49	GO:0060193	positive regulation of lipase activity
0.49	GO:0000281	mitotic cytokinesis
0.38	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.37	GO:0051056	regulation of small GTPase mediated signal transduction
0.36	GO:0007186	G-protein coupled receptor signaling pathway

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.37	GO:0005515	protein binding
0.35	GO:0004871	signal transducer activity

0.52	GO:0032420	stereocilium
0.50	GO:0097610	cell surface furrow
0.49	GO:0032155	cell division site part
0.45	GO:0005622	intracellular
0.40	GO:0005886	plasma membrane
0.39	GO:0043227	membrane-bounded organelle
0.37	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space

sp|Q9PT84|KCNH6_CHICK
Potassium voltage-gated channel subfamily H member 6
Search

KCNH2

0.57	Potassium voltage-gated channel subfamily H member 6

0.76	GO:0034765	regulation of ion transmembrane transport
0.72	GO:0071805	potassium ion transmembrane transport
0.58	GO:0086013	membrane repolarization during cardiac muscle cell action potential
0.57	GO:0008016	regulation of heart contraction
0.55	GO:0060047	heart contraction
0.54	GO:0035637	multicellular organismal signaling
0.54	GO:0099625	ventricular cardiac muscle cell membrane repolarization
0.52	GO:0043267	negative regulation of potassium ion transport
0.52	GO:0086010	membrane depolarization during action potential
0.51	GO:0070252	actin-mediated cell contraction

0.77	GO:0005249	voltage-gated potassium channel activity
0.54	GO:0055131	C3HC4-type RING finger domain binding
0.52	GO:0097110	scaffold protein binding
0.51	GO:0000155	phosphorelay sensor kinase activity
0.49	GO:0099094	ligand-gated cation channel activity
0.49	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0042803	protein homodimerization activity

0.54	GO:1902937	inward rectifier potassium channel complex
0.49	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0009986	cell surface
0.36	GO:0005635	nuclear envelope

0.51

EC:2.7.3

GO:0000155

tr|Q9PT88|Q9PT88_CHICK
RNA polymerase common subunit RPB6
Search

POLR2F

0.93	RNA polymerase II subunit F

0.58	GO:0006351	transcription, DNA-templated
0.35	GO:0035019	somatic stem cell population maintenance
0.35	GO:0032481	positive regulation of type I interferon production
0.35	GO:0060964	regulation of gene silencing by miRNA
0.35	GO:0045815	positive regulation of gene expression, epigenetic
0.34	GO:0008543	fibroblast growth factor receptor signaling pathway
0.34	GO:0016073	snRNA metabolic process
0.34	GO:0050434	positive regulation of viral transcription
0.34	GO:0006283	transcription-coupled nucleotide-excision repair
0.34	GO:0000398	mRNA splicing, via spliceosome

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.55	GO:0003677	DNA binding
0.33	GO:0004427	inorganic diphosphatase activity
0.33	GO:0000287	magnesium ion binding

0.80	GO:0005665	DNA-directed RNA polymerase II, core complex
0.47	GO:0005736	DNA-directed RNA polymerase I complex
0.47	GO:0005666	DNA-directed RNA polymerase III complex
0.37	GO:0001650	fibrillar center
0.33	GO:0005829	cytosol

0.70	EC:2.7.7.6	GO:0003899
0.33	KEGG:R00004	GO:0004427

sp|Q9PTD5|MTFR1_CHICK
Mitochondrial fission regulator 1
Search

MTFR1

0.95	Mitochondrial fission regulator 1

0.66	GO:0000266	mitochondrial fission
0.62	GO:0009060	aerobic respiration
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.32	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.65	GO:0005829	cytosol
0.61	GO:0005739	mitochondrion
0.53	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9PTG6|DCTN2_CHICK
Dynactin subunit 2
Search

DCTN2

0.96	Dynactin complex 50 kDa subunit

0.70	GO:0007017	microtubule-based process
0.54	GO:0032402	melanosome transport
0.54	GO:0071539	protein localization to centrosome
0.51	GO:0000278	mitotic cell cycle
0.51	GO:0008283	cell proliferation
0.43	GO:0007010	cytoskeleton organization
0.43	GO:0022402	cell cycle process
0.36	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0030719	P granule organization

0.53	GO:0030507	spectrin binding
0.50	GO:0019901	protein kinase binding
0.48	GO:0042802	identical protein binding
0.41	GO:0003774	motor activity

0.79	GO:0005869	dynactin complex
0.53	GO:0030426	growth cone
0.52	GO:0005813	centrosome
0.50	GO:0000776	kinetochore
0.49	GO:0031982	vesicle
0.46	GO:0005829	cytosol
0.43	GO:0030286	dynein complex
0.41	GO:0005874	microtubule
0.36	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space

tr|Q9PTI4|Q9PTI4_CHICK
Makorin 1
Search

MKRN1

0.85	E3 ubiquitin-protein ligase makorin-1

0.47	GO:0016567	protein ubiquitination
0.37	GO:0043491	protein kinase B signaling
0.37	GO:1990830	cellular response to leukemia inhibitory factor

0.59	GO:0016874	ligase activity
0.54	GO:0046872	metal ion binding
0.42	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0003682	chromatin binding
0.36	GO:0061659	ubiquitin-like protein ligase activity
0.34	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.35

GO:0005829

cytosol

0.59	EC:6	GO:0016874
0.42	KEGG:R03876	GO:0004842

sp|Q9PTJ6|CTDSL_CHICK
CTD small phosphatase-like protein
Search

CTDSPL

0.93	CTD small phosphatase like

0.68	GO:0016311	dephosphorylation
0.51	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.47	GO:0001933	negative regulation of protein phosphorylation
0.39	GO:0036211	protein modification process
0.38	GO:0044267	cellular protein metabolic process

0.68	GO:0016791	phosphatase activity
0.38	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0051015	actin filament binding
0.34	GO:0046872	metal ion binding

0.35	GO:0005634	nucleus
0.34	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.68

EC:3.1.3 EC:3.1.3.41

GO:0016791

sp|Q9PTL1|SPY1_CHICK
Protein sprouty homolog 1 (Fragment)
Search

0.85	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.84	GO:0046580	negative regulation of Ras protein signal transduction
0.76	GO:0042127	regulation of cell proliferation
0.76	GO:0001759	organ induction
0.70	GO:0007275	multicellular organism development
0.62	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway
0.61	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway
0.60	GO:0060602	branch elongation of an epithelium
0.60	GO:0034260	negative regulation of GTPase activity
0.59	GO:0045595	regulation of cell differentiation

0.49	GO:0043539	protein serine/threonine kinase activator activity
0.46	GO:0019901	protein kinase binding
0.34	GO:0030291	protein serine/threonine kinase inhibitor activity

0.50	GO:0005829	cytosol
0.47	GO:0005794	Golgi apparatus
0.46	GO:0005654	nucleoplasm
0.45	GO:0015630	microtubule cytoskeleton
0.39	GO:0032587	ruffle membrane
0.37	GO:0099513	polymeric cytoskeletal fiber
0.30	GO:0016021	integral component of membrane

sp|Q9PTL2|SPY2_CHICK
Protein sprouty homolog 2
Search

SPRY2

0.97	Sprouty RTK signaling antagonist 2

0.85	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.84	GO:0046580	negative regulation of Ras protein signal transduction
0.76	GO:0042127	regulation of cell proliferation
0.70	GO:0045595	regulation of cell differentiation
0.70	GO:0007275	multicellular organism development
0.61	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway
0.61	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway
0.60	GO:2000026	regulation of multicellular organismal development
0.60	GO:0060602	branch elongation of an epithelium
0.59	GO:0034260	negative regulation of GTPase activity

0.54	GO:0043539	protein serine/threonine kinase activator activity
0.52	GO:0019901	protein kinase binding
0.35	GO:0030291	protein serine/threonine kinase inhibitor activity

0.49	GO:0005829	cytosol
0.49	GO:0015630	microtubule cytoskeleton
0.46	GO:0005634	nucleus
0.42	GO:0005794	Golgi apparatus
0.41	GO:0032587	ruffle membrane
0.41	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part
0.38	GO:0099512	supramolecular fiber
0.30	GO:0016021	integral component of membrane

tr|Q9PTM3|Q9PTM3_CHICK
JAC
Search

0.72	Epidermal differentiation protein

0.48	GO:0007341	penetration of zona pellucida
0.47	GO:0007339	binding of sperm to zona pellucida
0.46	GO:0030317	flagellated sperm motility

0.68	GO:0045095	keratin filament
0.39	GO:0031966	mitochondrial membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9PTQ7|DMRT1_CHICK
Doublesex- and mab-3-related transcription factor 1
Search

DMRT1

0.91	DM domain expressed in testis protein 1

0.59	GO:0002176	male germ cell proliferation
0.57	GO:0030238	male sex determination
0.57	GO:0060008	Sertoli cell differentiation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2000020	positive regulation of male gonad development
0.57	GO:1900107	regulation of nodal signaling pathway
0.56	GO:0010468	regulation of gene expression
0.56	GO:0060903	positive regulation of meiosis I
0.55	GO:0008354	germ cell migration

0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0043565	sequence-specific DNA binding
0.51	GO:0044212	transcription regulatory region DNA binding
0.50	GO:0003682	chromatin binding
0.50	GO:0046872	metal ion binding
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0046982	protein heterodimerization activity
0.49	GO:0003690	double-stranded DNA binding
0.32	GO:0003735	structural constituent of ribosome

0.61	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044446	intracellular organelle part

sp|Q9PTR5|LIS1_CHICK
Lissencephaly-1 homolog
Search

PAFAH1B1

0.87	Platelet-activating factor acetylhydrolase IB subunit alpha

0.80	GO:0000132	establishment of mitotic spindle orientation
0.71	GO:0007399	nervous system development
0.68	GO:0030154	cell differentiation
0.67	GO:0051301	cell division
0.59	GO:0008090	retrograde axonal transport
0.57	GO:0090176	microtubule cytoskeleton organization involved in establishment of planar polarity
0.57	GO:0047496	vesicle transport along microtubule
0.56	GO:0051081	nuclear envelope disassembly
0.56	GO:0051661	maintenance of centrosome location
0.55	GO:0042249	establishment of planar polarity of embryonic epithelium

0.79	GO:0070840	dynein complex binding
0.53	GO:0051219	phosphoprotein binding
0.51	GO:0008017	microtubule binding
0.49	GO:0042803	protein homodimerization activity
0.41	GO:0016787	hydrolase activity
0.39	GO:0045505	dynein intermediate chain binding
0.37	GO:0034452	dynactin binding
0.37	GO:0043274	phospholipase binding
0.36	GO:0008201	heparin binding
0.36	GO:0047179	platelet-activating factor acetyltransferase activity

0.73	GO:0005874	microtubule
0.72	GO:0005815	microtubule organizing center
0.72	GO:0005875	microtubule associated complex
0.59	GO:0005819	spindle
0.59	GO:0031965	nuclear membrane
0.57	GO:1904115	axon cytoplasm
0.53	GO:0032420	stereocilium
0.53	GO:0000776	kinetochore
0.52	GO:0005938	cell cortex
0.51	GO:0031252	cell leading edge

0.41

GO:0016787

sp|Q9PTS8|ACHA9_CHICK
Neuronal acetylcholine receptor subunit alpha-9
Search

CHRNA9

0.97	LOW QUALITY PROTEIN: neuronal acetylcholine receptor subunit alpha-9

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.57	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
0.55	GO:0042472	inner ear morphogenesis
0.54	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.44	GO:0006812	cation transport

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.37	GO:0005262	calcium channel activity
0.34	GO:0005515	protein binding

0.78	GO:0045211	postsynaptic membrane
0.73	GO:0030054	cell junction
0.56	GO:0005892	acetylcholine-gated channel complex

tr|Q9PTS9|Q9PTS9_CHICK
Small-conductance calcium-activated potassium channel
Search

KCNN2

0.92	Small conductance calcium-activated potassium channel protein 2

0.73	GO:0071805	potassium ion transmembrane transport
0.48	GO:1901379	regulation of potassium ion transmembrane transport
0.36	GO:1903955	positive regulation of protein targeting to mitochondrion
0.36	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential
0.32	GO:0048168	regulation of neuronal synaptic plasticity

0.85	GO:0016286	small conductance calcium-activated potassium channel activity
0.79	GO:0005516	calmodulin binding
0.49	GO:0051393	alpha-actinin binding
0.45	GO:0019904	protein domain specific binding
0.45	GO:0042803	protein homodimerization activity
0.34	GO:0046982	protein heterodimerization activity
0.34	GO:0005249	voltage-gated potassium channel activity

0.47	GO:0043025	neuronal cell body
0.45	GO:0009986	cell surface
0.43	GO:0005886	plasma membrane
0.39	GO:0043197	dendritic spine
0.37	GO:0005737	cytoplasm
0.35	GO:0031594	neuromuscular junction
0.35	GO:0030175	filopodium
0.34	GO:0099512	supramolecular fiber
0.34	GO:0034705	potassium channel complex
0.34	GO:0012505	endomembrane system

sp|Q9PTU5|ESR2_CHICK
Estrogen receptor beta
Search

ESR2

0.94	Estrogen receptor beta transcript variant 2

0.85	GO:0030520	intracellular estrogen receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:1902680	positive regulation of RNA biosynthetic process
0.49	GO:0044093	positive regulation of molecular function
0.48	GO:1902679	negative regulation of RNA biosynthetic process
0.38	GO:0071392	cellular response to estradiol stimulus
0.37	GO:0008628	hormone-mediated apoptotic signaling pathway

0.85	GO:0030284	estrogen receptor activity
0.81	GO:0005496	steroid binding
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0001047	core promoter binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0042802	identical protein binding
0.48	GO:0003690	double-stranded DNA binding
0.48	GO:0019899	enzyme binding

0.61	GO:0005634	nucleus
0.43	GO:0005739	mitochondrion
0.35	GO:0043204	perikaryon
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0043005	neuron projection
0.34	GO:0005929	cilium
0.33	GO:0032993	protein-DNA complex
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0005576	extracellular region
0.32	GO:0044446	intracellular organelle part

sp|Q9PTW1|FZD6_CHICK
Frizzled-6 (Fragment)
Search

0.10	Frizzled homolog 6 (Fragment)

0.77	GO:0016055	Wnt signaling pathway
0.67	GO:0007275	multicellular organism development
0.55	GO:0048105	establishment of body hair planar orientation
0.55	GO:0090175	regulation of establishment of planar polarity
0.54	GO:0061351	neural precursor cell proliferation
0.54	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.53	GO:0043433	negative regulation of DNA binding transcription factor activity
0.53	GO:0060322	head development
0.53	GO:0030168	platelet activation
0.52	GO:0022405	hair cycle process

0.85	GO:0042813	Wnt-activated receptor activity
0.56	GO:0017147	Wnt-protein binding
0.52	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0004930	G-protein coupled receptor activity
0.37	GO:0030165	PDZ domain binding
0.35	GO:0001540	amyloid-beta binding

0.55	GO:0016327	apicolateral plasma membrane
0.53	GO:0045177	apical part of cell
0.38	GO:0030659	cytoplasmic vesicle membrane
0.38	GO:0009986	cell surface
0.38	GO:0032433	filopodium tip
0.37	GO:0016328	lateral plasma membrane
0.37	GO:0048786	presynaptic active zone
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.37	GO:0030424	axon

sp|Q9PTW3|FZD3_CHICK
Frizzled-3 (Fragment)
Search

0.77	GO:0016055	Wnt signaling pathway
0.69	GO:0007275	multicellular organism development
0.54	GO:0045976	negative regulation of mitotic cell cycle, embryonic
0.53	GO:1900118	negative regulation of execution phase of apoptosis
0.52	GO:0090175	regulation of establishment of planar polarity
0.52	GO:0036342	post-anal tail morphogenesis
0.52	GO:0060322	head development
0.52	GO:0001736	establishment of planar polarity
0.52	GO:0061351	neural precursor cell proliferation
0.52	GO:2000648	positive regulation of stem cell proliferation

0.85	GO:0042813	Wnt-activated receptor activity
0.56	GO:0017147	Wnt-protein binding
0.52	GO:0030165	PDZ domain binding
0.43	GO:0004930	G-protein coupled receptor activity
0.37	GO:0031625	ubiquitin protein ligase binding

0.52	GO:0032433	filopodium tip
0.51	GO:0016328	lateral plasma membrane
0.51	GO:0045177	apical part of cell
0.50	GO:0048786	presynaptic active zone
0.49	GO:0043025	neuronal cell body
0.49	GO:0098590	plasma membrane region
0.49	GO:0030425	dendrite
0.49	GO:0030424	axon
0.38	GO:0005737	cytoplasm
0.37	GO:0009986	cell surface

tr|Q9PTX1|Q9PTX1_CHICK
Paired-box containing protein Pax-2
Search

PAX2

0.94	LOW QUALITY PROTEIN: paired box protein Pax-2

0.68	GO:0007275	multicellular organism development
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.53	GO:0045918	negative regulation of cytolysis
0.51	GO:2000378	negative regulation of reactive oxygen species metabolic process
0.50	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.49	GO:0061138	morphogenesis of a branching epithelium
0.49	GO:0050679	positive regulation of epithelial cell proliferation

0.54	GO:0003677	DNA binding
0.46	GO:0001067	regulatory region nucleic acid binding
0.45	GO:0008134	transcription factor binding
0.38	GO:0016175	superoxide-generating NADPH oxidase activity
0.36	GO:0070742	C2H2 zinc finger domain binding
0.35	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.60	GO:0005634	nucleus
0.51	GO:0034451	centriolar satellite
0.45	GO:0005794	Golgi apparatus
0.44	GO:0043233	organelle lumen
0.36	GO:0005764	lysosome
0.36	GO:0032993	protein-DNA complex
0.34	GO:0043234	protein complex

0.38

EC:1.6.3

GO:0016175

sp|Q9PU36|PCLO_CHICK
Protein piccolo (Fragment)
Search

PCLO

0.92	Piccolo presynaptic cytomatrix protein a

0.84	GO:0007416	synapse assembly
0.62	GO:0099526	presynapse to nucleus signaling pathway
0.58	GO:0035418	protein localization to synapse
0.58	GO:0030073	insulin secretion
0.56	GO:0019933	cAMP-mediated signaling
0.55	GO:0017157	regulation of exocytosis
0.50	GO:0007010	cytoskeleton organization
0.34	GO:0016079	synaptic vesicle exocytosis
0.33	GO:0006903	vesicle targeting
0.33	GO:0140029	exocytic process

0.60	GO:0005522	profilin binding
0.46	GO:0046872	metal ion binding
0.34	GO:0005544	calcium-dependent phospholipid binding
0.33	GO:0098882	structural constituent of presynaptic active zone
0.32	GO:0001222	transcription corepressor binding

0.83	GO:0048786	presynaptic active zone
0.56	GO:0014069	postsynaptic density
0.56	GO:0099738	cell cortex region
0.34	GO:0030054	cell junction
0.34	GO:0099569	presynaptic cytoskeleton
0.33	GO:0070062	extracellular exosome
0.33	GO:0030863	cortical cytoskeleton
0.33	GO:0044317	rod spherule
0.33	GO:0044316	cone cell pedicle
0.32	GO:0097470	ribbon synapse

tr|Q9PU40|Q9PU40_CHICK
Tyrosine hydroxylase
Search

0.88	Tyrosine hydroxylase

0.79	GO:0042423	catecholamine biosynthetic process
0.68	GO:0009072	aromatic amino acid family metabolic process
0.62	GO:0007617	mating behavior
0.59	GO:0007625	grooming behavior
0.59	GO:0071625	vocalization behavior
0.59	GO:0042417	dopamine metabolic process
0.58	GO:0035176	social behavior
0.57	GO:0060416	response to growth hormone
0.55	GO:0042414	epinephrine metabolic process
0.53	GO:0001963	synaptic transmission, dopaminergic

0.83	GO:0004511	tyrosine 3-monooxygenase activity
0.62	GO:0005506	iron ion binding
0.46	GO:0019899	enzyme binding
0.41	GO:0004510	tryptophan 5-monooxygenase activity
0.38	GO:0034617	tetrahydrobiopterin binding
0.37	GO:0035240	dopamine binding
0.36	GO:0019825	oxygen binding
0.36	GO:0019904	protein domain specific binding
0.36	GO:0016597	amino acid binding
0.34	GO:0005179	hormone activity

0.53	GO:0033162	melanosome membrane
0.52	GO:0005790	smooth endoplasmic reticulum
0.52	GO:0043204	perikaryon
0.49	GO:0030424	axon
0.47	GO:0009898	cytoplasmic side of plasma membrane
0.42	GO:0005634	nucleus
0.37	GO:0043679	axon terminus
0.36	GO:0008021	synaptic vesicle
0.36	GO:0030425	dendrite
0.36	GO:0070852	cell body fiber

0.83

EC:1.14.16.2

GO:0004511

sp|Q9PU41|CCKN_CHICK
Cholecystokinin
Search

CCK

0.97	Preprocholecystokinin

0.76	GO:0010469	regulation of receptor activity
0.53	GO:0042755	eating behavior
0.52	GO:0001764	neuron migration
0.51	GO:0007409	axonogenesis
0.39	GO:0031667	response to nutrient levels
0.38	GO:0014049	positive regulation of glutamate secretion
0.38	GO:0051901	positive regulation of mitochondrial depolarization
0.38	GO:0007586	digestion
0.38	GO:0051930	regulation of sensory perception of pain
0.38	GO:0001836	release of cytochrome c from mitochondria

0.79	GO:0005179	hormone activity
0.33	GO:0090729	toxin activity

0.66	GO:0005576	extracellular region
0.51	GO:0030424	axon
0.37	GO:0043204	perikaryon
0.37	GO:0043679	axon terminus
0.37	GO:0030425	dendrite
0.30	GO:0016020	membrane

sp|Q9PU45|RADI_CHICK
Radixin
Search

RDX

0.96	Radixin isoform C

0.58	GO:1902966	positive regulation of protein localization to early endosome
0.58	GO:2000643	positive regulation of early endosome to late endosome transport
0.57	GO:0034111	negative regulation of homotypic cell-cell adhesion
0.57	GO:0045792	negative regulation of cell size
0.56	GO:1903392	negative regulation of adherens junction organization
0.56	GO:1900027	regulation of ruffle assembly
0.56	GO:0061028	establishment of endothelial barrier
0.56	GO:0034260	negative regulation of GTPase activity
0.56	GO:0030033	microvillus assembly
0.55	GO:0097067	cellular response to thyroid hormone stimulus

0.72	GO:0003779	actin binding
0.55	GO:0051117	ATPase binding
0.53	GO:0045296	cadherin binding
0.50	GO:0019904	protein domain specific binding
0.49	GO:0042803	protein homodimerization activity
0.36	GO:0051018	protein kinase A binding
0.35	GO:0003723	RNA binding

0.69	GO:0005856	cytoskeleton
0.54	GO:0005902	microvillus
0.54	GO:0032420	stereocilium
0.53	GO:0005925	focal adhesion
0.53	GO:0016324	apical plasma membrane
0.53	GO:0030175	filopodium
0.52	GO:0001726	ruffle
0.52	GO:0030027	lamellipodium
0.52	GO:0043209	myelin sheath
0.50	GO:0044448	cell cortex part

sp|Q9PU47|PDLI3_CHICK
PDZ and LIM domain protein 3
Search

PDLIM3

0.89	Actinin-associated LIM protein 2

0.47	GO:0007507	heart development
0.46	GO:0007015	actin filament organization
0.34	GO:0016311	dephosphorylation

0.54	GO:0046872	metal ion binding
0.50	GO:0008307	structural constituent of muscle
0.45	GO:0008092	cytoskeletal protein binding
0.36	GO:0004035	alkaline phosphatase activity

0.47	GO:0015629	actin cytoskeleton
0.44	GO:0030018	Z disc
0.40	GO:0030027	lamellipodium
0.39	GO:0005925	focal adhesion
0.37	GO:0044430	cytoskeletal part

0.36

EC:3.1.3.1

GO:0004035

tr|Q9PU52|Q9PU52_CHICK
Iroquois homologue 2
Search

IRX2

0.94	Iroquois-class homeodomain protein irx-2

0.62	GO:0072086	specification of loop of Henle identity
0.59	GO:0072272	proximal/distal pattern formation involved in metanephric nephron development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0048523	negative regulation of cellular process
0.50	GO:0010558	negative regulation of macromolecule biosynthetic process
0.49	GO:0051172	negative regulation of nitrogen compound metabolic process
0.46	GO:0060042	retina morphogenesis in camera-type eye
0.45	GO:0051961	negative regulation of nervous system development

0.64	GO:0043565	sequence-specific DNA binding
0.36	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.33	GO:0004969	histamine receptor activity

0.61	GO:0005634	nucleus
0.43	GO:0030424	axon
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9PU53|TERF2_CHICK
Telomeric repeat-binding factor 2
Search

0.43	Telomeric repeat binding factor 2

0.86	GO:0031848	protection from non-homologous end joining at telomere
0.58	GO:1903770	negative regulation of beta-galactosidase activity
0.58	GO:0032208	negative regulation of telomere maintenance via recombination
0.58	GO:1905839	negative regulation of telomeric D-loop disassembly
0.57	GO:1905778	negative regulation of exonuclease activity
0.57	GO:1904430	negative regulation of t-circle formation
0.57	GO:0031627	telomeric loop formation
0.56	GO:0061820	telomeric D-loop disassembly
0.56	GO:1904354	negative regulation of telomere capping
0.56	GO:2000773	negative regulation of cellular senescence

0.82	GO:0042162	telomeric DNA binding
0.75	GO:0042803	protein homodimerization activity
0.54	GO:0003720	telomerase activity
0.53	GO:0098847	sequence-specific single stranded DNA binding
0.53	GO:0008022	protein C-terminus binding
0.48	GO:0003690	double-stranded DNA binding
0.48	GO:0044877	macromolecular complex binding
0.48	GO:0019899	enzyme binding

0.82	GO:0000784	nuclear chromosome, telomeric region
0.54	GO:0000782	telomere cap complex
0.53	GO:0030870	Mre11 complex
0.50	GO:0016604	nuclear body
0.43	GO:0001673	male germ cell nucleus
0.43	GO:1904115	axon cytoplasm
0.30	GO:0016020	membrane

0.54

EC:2.7.7

GO:0003720

tr|Q9PU55|Q9PU55_CHICK
Lymphoid transcription factor
Search

IKZF3

0.95	Zinc finger protein Aiolos

0.46	GO:0045577	regulation of B cell differentiation
0.46	GO:0030888	regulation of B cell proliferation
0.43	GO:0042113	B cell activation
0.43	GO:0045944	positive regulation of transcription by RNA polymerase II
0.42	GO:0042981	regulation of apoptotic process
0.41	GO:0006366	transcription by RNA polymerase II
0.38	GO:0007498	mesoderm development

0.51	GO:0003676	nucleic acid binding
0.43	GO:0042803	protein homodimerization activity
0.42	GO:0046982	protein heterodimerization activity
0.42	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.36	GO:0046872	metal ion binding

0.40	GO:0005654	nucleoplasm
0.39	GO:0005829	cytosol
0.36	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q9PUA4|Q9PUA4_CHICK
G/T mismatch DNA glycosylase
Search

TDG

0.92	LOW QUALITY PROTEIN: G/T mismatch-specific thymine DNA glycosylase

0.64	GO:0006281	DNA repair
0.60	GO:1902544	regulation of DNA N-glycosylase activity
0.59	GO:0035562	negative regulation of chromatin binding
0.56	GO:0032091	negative regulation of protein binding
0.56	GO:0080111	DNA demethylation
0.53	GO:0040029	regulation of gene expression, epigenetic
0.53	GO:0000122	negative regulation of transcription by RNA polymerase II
0.51	GO:0009790	embryo development
0.38	GO:0009223	pyrimidine deoxyribonucleotide catabolic process
0.35	GO:0016569	covalent chromatin modification

0.73	GO:0019104	DNA N-glycosylase activity
0.58	GO:0031404	chloride ion binding
0.58	GO:0032183	SUMO binding
0.57	GO:0005080	protein kinase C binding
0.57	GO:0043621	protein self-association
0.54	GO:0031402	sodium ion binding
0.53	GO:0001104	RNA polymerase II transcription cofactor activity
0.52	GO:0030983	mismatched DNA binding
0.52	GO:0042803	protein homodimerization activity
0.47	GO:0000287	magnesium ion binding

0.56	GO:0016605	PML body
0.42	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.73

EC:3.2.2

GO:0019104

sp|Q9PUB4|CP26A_CHICK
Cytochrome P450 26A1
Search

CYP26A1

0.97	Cytochrome P450 family 26 subfamily A polypeptide 1

0.79	GO:0034653	retinoic acid catabolic process
0.63	GO:0006805	xenobiotic metabolic process
0.53	GO:0014032	neural crest cell development
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0016125	sterol metabolic process
0.51	GO:0009952	anterior/posterior pattern specification
0.50	GO:0007417	central nervous system development
0.50	GO:0048284	organelle fusion
0.38	GO:0071300	cellular response to retinoic acid
0.38	GO:0048384	retinoic acid receptor signaling pathway

0.81	GO:0008401	retinoic acid 4-hydroxylase activity
0.77	GO:0001972	retinoic acid binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.61	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

0.30

GO:0016020

membrane

0.61

EC:1.14.13

GO:0016709

sp|Q9PUF6|PGFRA_CHICK
Platelet-derived growth factor receptor alpha
Search

PDGFRA

0.68	Platelet-derived growth factor receptor alpha

0.85	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.64	GO:0006935	chemotaxis
0.63	GO:0007275	multicellular organism development
0.55	GO:0023019	signal transduction involved in regulation of gene expression
0.55	GO:0008210	estrogen metabolic process
0.54	GO:0060325	face morphogenesis
0.54	GO:0060021	palate development
0.53	GO:1904888	cranial skeletal system development
0.53	GO:0022602	ovulation cycle process

0.85	GO:0005018	platelet-derived growth factor alpha-receptor activity
0.56	GO:0048407	platelet-derived growth factor binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0032403	protein complex binding
0.46	GO:0038085	vascular endothelial growth factor binding
0.45	GO:0005161	platelet-derived growth factor receptor binding
0.43	GO:0005021	vascular endothelial growth factor-activated receptor activity

0.53	GO:0005902	microvillus
0.52	GO:0009897	external side of plasma membrane
0.43	GO:0005634	nucleus
0.40	GO:0030054	cell junction
0.39	GO:0031226	intrinsic component of plasma membrane
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:0005737	cytoplasm
0.37	GO:0043234	protein complex
0.36	GO:0044446	intracellular organelle part
0.35	GO:0030424	axon

tr|Q9PUJ4|Q9PUJ4_CHICK
Ephrin-B2
Search

0.79	GO:0048013	ephrin receptor signaling pathway
0.58	GO:0031295	T cell costimulation
0.58	GO:0002042	cell migration involved in sprouting angiogenesis
0.57	GO:1903849	positive regulation of aorta morphogenesis
0.56	GO:1901216	positive regulation of neuron death
0.56	GO:0048699	generation of neurons
0.56	GO:0048845	venous blood vessel morphogenesis
0.55	GO:0008284	positive regulation of cell proliferation
0.55	GO:0010839	negative regulation of keratinocyte proliferation
0.55	GO:0072178	nephric duct morphogenesis

0.81	GO:0046875	ephrin receptor binding
0.35	GO:0104005	hijacked molecular function
0.33	GO:0016301	kinase activity

0.44	GO:0005886	plasma membrane
0.42	GO:0045121	membrane raft
0.38	GO:0005634	nucleus
0.36	GO:0005925	focal adhesion
0.35	GO:0005737	cytoplasm
0.34	GO:0070062	extracellular exosome
0.33	GO:0045202	synapse
0.30	GO:0016021	integral component of membrane

sp|Q9PUU8|LECT1_CHICK
Leukocyte cell-derived chemotaxin 1
Search

CNMD

0.97	Leukocyte cell-derived chemotaxin 1

0.66	GO:0016525	negative regulation of angiogenesis
0.48	GO:0001886	endothelial cell morphogenesis
0.47	GO:0001937	negative regulation of endothelial cell proliferation
0.44	GO:0061448	connective tissue development
0.43	GO:0001501	skeletal system development
0.41	GO:0048513	animal organ development
0.40	GO:0007585	respiratory gaseous exchange
0.39	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway
0.36	GO:0006029	proteoglycan metabolic process
0.35	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

0.34	GO:0005509	calcium ion binding
0.32	GO:0005515	protein binding

0.42	GO:0005578	proteinaceous extracellular matrix
0.40	GO:0012505	endomembrane system
0.34	GO:0044428	nuclear part
0.33	GO:0031967	organelle envelope
0.33	GO:0005886	plasma membrane
0.33	GO:0009986	cell surface
0.31	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q9PV94|RSMB_CHICK
Small nuclear ribonucleoprotein-associated protein B'
Search

0.85	Small nuclear ribonucleoprotein-associated proteins B and B'

0.51	GO:0000398	mRNA splicing, via spliceosome
0.45	GO:0022618	ribonucleoprotein complex assembly
0.43	GO:0008213	protein alkylation
0.41	GO:0043414	macromolecule methylation
0.37	GO:0009725	response to hormone
0.35	GO:0008334	histone mRNA metabolic process
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0007420	brain development
0.34	GO:0051170	nuclear import

0.56	GO:0003723	RNA binding
0.35	GO:1990447	U2 snRNP binding
0.35	GO:1990446	U1 snRNP binding
0.34	GO:0005515	protein binding

0.60	GO:0030529	intracellular ribonucleoprotein complex
0.58	GO:0005634	nucleus
0.57	GO:0019013	viral nucleocapsid
0.52	GO:0120114	Sm-like protein family complex
0.49	GO:0034709	methylosome
0.46	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.43	GO:0005829	cytosol
0.40	GO:0043234	protein complex
0.36	GO:0070062	extracellular exosome

tr|Q9PVG4|Q9PVG4_CHICK
CTwist
Search

TWIST1

0.93	Basic helix-loop-helix transcription factor twist

0.55	GO:0045668	negative regulation of osteoblast differentiation
0.52	GO:2000793	cell proliferation involved in heart valve development
0.51	GO:0140051	positive regulation of endocardial cushion to mesenchymal transition
0.51	GO:2000800	regulation of endocardial cushion to mesenchymal transition involved in heart valve formation
0.50	GO:2000276	negative regulation of oxidative phosphorylation uncoupler activity
0.50	GO:0033128	negative regulation of histone phosphorylation
0.50	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway
0.50	GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis
0.50	GO:0003180	aortic valve morphogenesis
0.50	GO:0032000	positive regulation of fatty acid beta-oxidation

0.68	GO:0046983	protein dimerization activity
0.49	GO:0043425	bHLH transcription factor binding
0.49	GO:0070888	E-box binding
0.45	GO:0019904	protein domain specific binding
0.44	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.44	GO:0042802	identical protein binding
0.35	GO:0001158	enhancer sequence-specific DNA binding
0.35	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.35	GO:0003682	chromatin binding

0.46	GO:0005634	nucleus
0.42	GO:0070013	intracellular organelle lumen
0.39	GO:0044446	intracellular organelle part
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0005737	cytoplasm
0.35	GO:0005667	transcription factor complex

tr|Q9PVL6|Q9PVL6_CHICK
Mitochondrial carrier homolog 2
Search

MTCH2

0.62	Mitochondrial carrier like protein 2

0.51	GO:0070585	protein localization to mitochondrion
0.47	GO:0043065	positive regulation of apoptotic process
0.44	GO:0045444	fat cell differentiation
0.44	GO:0001889	liver development
0.44	GO:0048565	digestive tract development
0.40	GO:2001056	positive regulation of cysteine-type endopeptidase activity
0.40	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.39	GO:0010917	negative regulation of mitochondrial membrane potential
0.39	GO:0035701	hematopoietic stem cell migration
0.39	GO:0061484	hematopoietic stem cell homeostasis

0.34	GO:0004181	metallocarboxypeptidase activity
0.33	GO:0008270	zinc ion binding

0.41	GO:0005739	mitochondrion
0.38	GO:0070062	extracellular exosome
0.37	GO:0031968	organelle outer membrane
0.37	GO:0019866	organelle inner membrane
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0004181

sp|Q9PVN2|VAX1_CHICK
Ventral anterior homeobox 1
Search

VAX1

0.96	Ventral anterior homeobox 1

0.76	GO:0007411	axon guidance
0.75	GO:0007420	brain development
0.63	GO:0001654	eye development
0.61	GO:0007406	negative regulation of neuroblast proliferation
0.59	GO:0035914	skeletal muscle cell differentiation
0.59	GO:0060021	palate development
0.58	GO:0001764	neuron migration
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression

0.62	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0031490	chromatin DNA binding
0.32	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm

sp|Q9PVX0|RX2_CHICK
Retinal homeobox protein Rx2
Search

RAX

0.93	Retina and anterior neural fold homeobox

0.73	GO:0043010	camera-type eye development
0.68	GO:0006366	transcription by RNA polymerase II
0.66	GO:0007601	visual perception
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0021854	hypothalamus development
0.51	GO:0060173	limb development
0.50	GO:0007389	pattern specification process
0.48	GO:1902680	positive regulation of RNA biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.56	GO:0003700	DNA binding transcription factor activity
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.37	GO:0019905	syntaxin binding
0.33	GO:0003746	translation elongation factor activity

0.61

GO:0005634

nucleus

sp|Q9PVY0|RX1_CHICK
Retinal homeobox protein Rx1
Search

0.94	Retina and anterior neural fold homeobox

0.77	GO:0043010	camera-type eye development
0.72	GO:0007601	visual perception
0.71	GO:0006366	transcription by RNA polymerase II
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:0021854	hypothalamus development
0.45	GO:0060173	limb development
0.45	GO:1902680	positive regulation of RNA biosynthetic process
0.44	GO:0007389	pattern specification process

0.64	GO:0043565	sequence-specific DNA binding
0.58	GO:0003700	DNA binding transcription factor activity
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003690	double-stranded DNA binding
0.37	GO:0019905	syntaxin binding

0.61

GO:0005634

nucleus

tr|Q9PW10|Q9PW10_CHICK
CHUNK-1 protein
Search

sp|Q9PW38|GEPH_CHICK
Gephyrin
Search

GPHN

0.87	Gephyrin a

0.79	GO:0032324	molybdopterin cofactor biosynthetic process
0.73	GO:0006777	Mo-molybdopterin cofactor biosynthetic process
0.53	GO:0072578	neurotransmitter-gated ion channel clustering
0.51	GO:0001941	postsynaptic membrane organization
0.44	GO:0018315	molybdenum incorporation into molybdenum-molybdopterin complex
0.42	GO:0010038	response to metal ion
0.36	GO:0055114	oxidation-reduction process
0.34	GO:0098970	postsynaptic neurotransmitter receptor diffusion trapping
0.34	GO:0007529	establishment of synaptic specificity at neuromuscular junction
0.34	GO:0007416	synapse assembly

0.43	GO:0061598	molybdopterin adenylyltransferase activity
0.43	GO:0008940	nitrate reductase activity
0.43	GO:0061599	molybdopterin molybdotransferase activity
0.42	GO:0043546	molybdopterin cofactor binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0005515	protein binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0046872	metal ion binding
0.33	GO:0060090	molecular adaptor activity

0.45	GO:0030425	dendrite
0.44	GO:0045211	postsynaptic membrane
0.38	GO:0030054	cell junction
0.37	GO:0005856	cytoskeleton
0.34	GO:0005737	cytoplasm
0.34	GO:0060077	inhibitory synapse
0.34	GO:0099572	postsynaptic specialization
0.33	GO:0043025	neuronal cell body
0.33	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.32	GO:0044422	organelle part

0.43

EC:2.7.7.75

GO:0061598

sp|Q9PW70|CISH_CHICK
Cytokine-inducible SH2-containing protein
Search

CISH

0.97	Cytokine-inducible inhibitor of signalling type IV

0.65	GO:0016567	protein ubiquitination
0.62	GO:0035556	intracellular signal transduction
0.56	GO:0046426	negative regulation of JAK-STAT cascade
0.53	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.49	GO:0040008	regulation of growth
0.49	GO:0046627	negative regulation of insulin receptor signaling pathway
0.47	GO:0006469	negative regulation of protein kinase activity
0.46	GO:0019221	cytokine-mediated signaling pathway
0.43	GO:0051128	regulation of cellular component organization
0.42	GO:0060749	mammary gland alveolus development

0.52	GO:0008269	JAK pathway signal transduction adaptor activity
0.51	GO:0005159	insulin-like growth factor receptor binding
0.47	GO:0004860	protein kinase inhibitor activity
0.42	GO:0005131	growth hormone receptor binding
0.33	GO:0005070	SH3/SH2 adaptor activity
0.33	GO:0003779	actin binding

0.45	GO:0005622	intracellular
0.41	GO:0005886	plasma membrane

sp|Q9PW71|DUS4_CHICK
Dual specificity protein phosphatase 4
Search

DUSP4

0.72	Dual specificity protein phosphatase

0.84	GO:0000188	inactivation of MAPK activity
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.57	GO:0035970	peptidyl-threonine dephosphorylation
0.56	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.53	GO:0001706	endoderm formation
0.41	GO:0060795	cell fate commitment involved in formation of primary germ layer
0.41	GO:0001708	cell fate specification
0.40	GO:0042981	regulation of apoptotic process
0.39	GO:0033574	response to testosterone
0.38	GO:0032355	response to estradiol

0.85	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.60	GO:0008330	protein tyrosine/threonine phosphatase activity
0.58	GO:1990439	MAP kinase serine/threonine phosphatase activity
0.38	GO:0019838	growth factor binding
0.32	GO:0016301	kinase activity

0.47	GO:0005634	nucleus
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:3.1.3

GO:0017017

sp|Q9PW72|PDLI4_CHICK
PDZ and LIM domain protein 4
Search

PDLIM4

0.97	PDZ and LIM domain protein 4

0.52	GO:0031532	actin cytoskeleton reorganization
0.43	GO:0098976	excitatory chemical synaptic transmission
0.39	GO:0098609	cell-cell adhesion
0.36	GO:0060173	limb development
0.36	GO:2001141	regulation of RNA biosynthetic process
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0001666	response to hypoxia
0.35	GO:0010468	regulation of gene expression
0.35	GO:0051496	positive regulation of stress fiber assembly
0.33	GO:0055085	transmembrane transport

0.58	GO:0051393	alpha-actinin binding
0.56	GO:0019903	protein phosphatase binding
0.53	GO:0046872	metal ion binding
0.52	GO:0042803	protein homodimerization activity
0.42	GO:0098641	cadherin binding involved in cell-cell adhesion
0.40	GO:0003713	transcription coactivator activity
0.35	GO:0051015	actin filament binding
0.33	GO:0022857	transmembrane transporter activity

0.57	GO:0031941	filamentous actin
0.57	GO:0097517	contractile actin filament bundle
0.56	GO:0042641	actomyosin
0.55	GO:0030027	lamellipodium
0.54	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0005634	nucleus
0.44	GO:0034777	recycling endosome lumen
0.43	GO:0031905	early endosome lumen
0.42	GO:0030054	cell junction
0.41	GO:0055038	recycling endosome membrane

sp|Q9PWA0|RGS17_CHICK
Regulator of G-protein signaling 17
Search

RGS17

0.92	Regulator of G protein signaling 17

0.75	GO:0043547	positive regulation of GTPase activity
0.51	GO:0009968	negative regulation of signal transduction
0.40	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0005096	GTPase activator activity
0.38	GO:0005515	protein binding

0.72	GO:0031410	cytoplasmic vesicle
0.55	GO:0005886	plasma membrane
0.51	GO:0043005	neuron projection
0.50	GO:0045202	synapse
0.49	GO:0030054	cell junction
0.45	GO:0005634	nucleus
0.41	GO:0005802	trans-Golgi network

sp|Q9PWA1|RGS20_CHICK
Regulator of G-protein signaling 20
Search

RGS20

0.95	Regulator of G-protein signaling 20

0.65	GO:0043547	positive regulation of GTPase activity
0.52	GO:0009968	negative regulation of signal transduction
0.42	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.39	GO:0007186	G-protein coupled receptor signaling pathway

0.66	GO:0005096	GTPase activator activity
0.38	GO:0005515	protein binding

0.74	GO:0005802	trans-Golgi network
0.63	GO:0031410	cytoplasmic vesicle
0.50	GO:0005886	plasma membrane
0.46	GO:0005634	nucleus
0.40	GO:0043005	neuron projection
0.39	GO:0045202	synapse
0.39	GO:0030054	cell junction

tr|Q9PWA2|Q9PWA2_CHICK
GTPase activating protein Rap1-GAP
Search

RAP1GAP

0.85	Rap1 GTPase-activating protein 1

0.74	GO:0051056	regulation of small GTPase mediated signal transduction
0.74	GO:0043547	positive regulation of GTPase activity
0.40	GO:1903697	negative regulation of microvillus assembly
0.40	GO:1904441	regulation of thyroid gland epithelial cell proliferation
0.40	GO:1990790	response to glial cell derived neurotrophic factor
0.39	GO:1904425	negative regulation of GTP binding
0.38	GO:0050680	negative regulation of epithelial cell proliferation
0.38	GO:0045665	negative regulation of neuron differentiation
0.37	GO:0071363	cellular response to growth factor stimulus
0.37	GO:0050766	positive regulation of phagocytosis

0.74	GO:0005096	GTPase activator activity
0.37	GO:0017016	Ras GTPase binding
0.37	GO:0042803	protein homodimerization activity
0.33	GO:0003924	GTPase activity

0.38	GO:0005829	cytosol
0.37	GO:0012505	endomembrane system
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.37	GO:0030424	axon
0.36	GO:0031410	cytoplasmic vesicle
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0031984	organelle subcompartment
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0005813	centrosome

sp|Q9PWA3|GRIN2_CHICK
GRIN2-like protein
Search

GPRIN2

0.74	G protein-regulated inducer of neurite outgrowth 2

0.64	GO:0031175	neuron projection development
0.39	GO:0022900	electron transport chain

0.47	GO:0005515	protein binding
0.40	GO:0020037	heme binding
0.40	GO:0009055	electron transfer activity
0.37	GO:0046872	metal ion binding

0.48	GO:0005886	plasma membrane
0.47	GO:0030426	growth cone

sp|Q9PWB0|CER1_CHICK
Cerberus
Search

CER1

0.97	Cerberus 1 homolog (Xenopus laevis)

0.65	GO:0035582	sequestering of BMP in extracellular matrix
0.64	GO:2000381	negative regulation of mesoderm development
0.63	GO:0032926	negative regulation of activin receptor signaling pathway
0.63	GO:0048263	determination of dorsal identity
0.63	GO:0003419	growth plate cartilage chondrocyte proliferation
0.61	GO:0023019	signal transduction involved in regulation of gene expression
0.61	GO:0030282	bone mineralization
0.59	GO:0042074	cell migration involved in gastrulation
0.58	GO:0009948	anterior/posterior axis specification
0.58	GO:0001657	ureteric bud development

0.64	GO:0016015	morphogen activity
0.63	GO:0036122	BMP binding
0.53	GO:0042803	protein homodimerization activity
0.40	GO:0005125	cytokine activity
0.36	GO:0017147	Wnt-protein binding
0.35	GO:0038100	nodal binding

0.66	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q9PWE8|TBX5_CHICK
T-box transcription factor TBX5
Search

TBX5

0.97	Regeneration blastema forelimb-specific Tbx

0.61	GO:0035108	limb morphogenesis
0.61	GO:0035113	embryonic appendage morphogenesis
0.61	GO:0060039	pericardium development
0.60	GO:0051891	positive regulation of cardioblast differentiation
0.60	GO:0060044	negative regulation of cardiac muscle cell proliferation
0.58	GO:0003218	cardiac left ventricle formation
0.58	GO:0003181	atrioventricular valve morphogenesis
0.58	GO:0003166	bundle of His development
0.58	GO:0072513	positive regulation of secondary heart field cardioblast proliferation
0.57	GO:2001141	regulation of RNA biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0008134	transcription factor binding
0.38	GO:0030274	LIM domain binding
0.37	GO:0097110	scaffold protein binding
0.36	GO:0051087	chaperone binding

0.61	GO:0005634	nucleus
0.50	GO:0032993	protein-DNA complex
0.41	GO:0015629	actin cytoskeleton
0.39	GO:0005737	cytoplasm
0.36	GO:0099513	polymeric cytoskeletal fiber
0.34	GO:0005667	transcription factor complex
0.33	GO:0070013	intracellular organelle lumen
0.30	GO:0016020	membrane

sp|Q9PWH2|FZD10_CHICK
Frizzled-10
Search

FZD10

0.96	Frizzled class receptor 10

0.76	GO:0016055	Wnt signaling pathway
0.69	GO:0007275	multicellular organism development
0.53	GO:0034260	negative regulation of GTPase activity
0.53	GO:0043507	positive regulation of JUN kinase activity
0.49	GO:0032956	regulation of actin cytoskeleton organization
0.49	GO:0043547	positive regulation of GTPase activity
0.45	GO:0090504	epiboly
0.43	GO:0007186	G-protein coupled receptor signaling pathway
0.39	GO:1904394	negative regulation of skeletal muscle acetylcholine-gated channel clustering
0.39	GO:0071157	negative regulation of cell cycle arrest

0.78	GO:0042813	Wnt-activated receptor activity
0.54	GO:0017147	Wnt-protein binding
0.43	GO:0004930	G-protein coupled receptor activity
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity
0.32	GO:0046872	metal ion binding
0.32	GO:0003677	DNA binding

0.50	GO:0009986	cell surface
0.46	GO:0005654	nucleoplasm
0.38	GO:0005737	cytoplasm
0.38	GO:0031527	filopodium membrane
0.33	GO:0005887	integral component of plasma membrane

tr|Q9PWI5|Q9PWI5_CHICK
Interferon alpha
Search

0.85	Interferon type B

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.58	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.58	GO:0002323	natural killer cell activation involved in immune response
0.57	GO:0042100	B cell proliferation
0.56	GO:0002286	T cell activation involved in immune response
0.56	GO:0043330	response to exogenous dsRNA
0.55	GO:0030183	B cell differentiation
0.54	GO:0002250	adaptive immune response
0.54	GO:0006959	humoral immune response

0.81	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.51	GO:0032403	protein complex binding

0.73

GO:0005615

extracellular space

tr|Q9PWK1|Q9PWK1_CHICK
Pepsinogen C
Search

PGC

0.92	Progastricsin

0.61	GO:0006508	proteolysis
0.54	GO:0002803	positive regulation of antibacterial peptide production
0.49	GO:0006914	autophagy
0.46	GO:0030163	protein catabolic process
0.45	GO:0007586	digestion
0.32	GO:0006629	lipid metabolic process

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity

0.47	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

tr|Q9PWP1|Q9PWP1_CHICK
Neurogenin 1
Search

NEUROG1

0.96	Neurogenin 1

0.73	GO:0022008	neurogenesis
0.59	GO:0048513	animal organ development
0.58	GO:1905748	hard palate morphogenesis
0.58	GO:1905747	negative regulation of saliva secretion
0.58	GO:0071626	mastication
0.58	GO:0051091	positive regulation of DNA binding transcription factor activity
0.58	GO:0098583	learned vocalization behavior
0.58	GO:0007356	thorax and anterior abdomen determination
0.58	GO:0021650	vestibulocochlear nerve formation
0.58	GO:0051960	regulation of nervous system development

0.68	GO:0046983	protein dimerization activity
0.58	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0003682	chromatin binding
0.55	GO:0000989	transcription factor activity, transcription factor binding
0.49	GO:0042802	identical protein binding
0.48	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0001047	core promoter binding
0.37	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0008009	chemokine activity
0.32	GO:0046872	metal ion binding

0.55	GO:0043204	perikaryon
0.42	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q9PWR1|KCAB1_CHICK
Voltage-gated potassium channel subunit beta-1
Search

KCNAB1

0.95	Voltage-gated potassium channel subunit beta-1

0.70	GO:0006813	potassium ion transport
0.59	GO:0098662	inorganic cation transmembrane transport
0.57	GO:1903817	negative regulation of voltage-gated potassium channel activity
0.53	GO:0007611	learning or memory
0.42	GO:1902259	regulation of delayed rectifier potassium channel activity
0.40	GO:0045445	myoblast differentiation
0.39	GO:0060539	diaphragm development
0.38	GO:0007519	skeletal muscle tissue development
0.38	GO:0002244	hematopoietic progenitor cell differentiation
0.38	GO:0050905	neuromuscular process

0.74	GO:0005249	voltage-gated potassium channel activity
0.58	GO:0015459	potassium channel regulator activity
0.53	GO:0070402	NADPH binding
0.50	GO:0019904	protein domain specific binding
0.42	GO:0004033	aldo-keto reductase (NADP) activity
0.39	GO:0044325	ion channel binding

0.53	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.53	GO:0034705	potassium channel complex
0.48	GO:0005829	cytosol
0.47	GO:0005887	integral component of plasma membrane
0.42	GO:0044224	juxtaparanode region of axon
0.40	GO:1990635	proximal dendrite
0.39	GO:0032839	dendrite cytoplasm
0.38	GO:0043204	perikaryon
0.38	GO:0043679	axon terminus
0.37	GO:0014069	postsynaptic density

0.42

EC:1.1.1

GO:0004033

sp|Q9PWR4|VSIG1_CHICK
V-set and immunoglobulin domain-containing protein 1
Search

VSIG1

0.97	V-set and immunoglobulin domain-containing protein 1

0.86	GO:0030277	maintenance of gastrointestinal epithelium
0.85	GO:0003382	epithelial cell morphogenesis

0.56	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q9W601|Q9W601_CHICK
Pax-5 protein
Search

PAX5

0.96	B-cell-specific transcription factor

0.70	GO:0007275	multicellular organism development
0.63	GO:0051573	negative regulation of histone H3-K9 methylation
0.60	GO:1904888	cranial skeletal system development
0.59	GO:0030534	adult behavior
0.58	GO:0014706	striated muscle tissue development
0.58	GO:0006351	transcription, DNA-templated
0.58	GO:0007568	aging
0.57	GO:0061061	muscle structure development
0.57	GO:0060322	head development
0.57	GO:2001141	regulation of RNA biosynthetic process

0.58	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.58	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.52	GO:0005829	cytosol
0.51	GO:0031974	membrane-enclosed lumen
0.47	GO:0043232	intracellular non-membrane-bounded organelle
0.46	GO:0044446	intracellular organelle part
0.35	GO:0005667	transcription factor complex

tr|Q9W610|Q9W610_CHICK
ATF4
Search

ATF4

0.96	Cyclic AMP-dependent transcription factor ATF-4

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:1903351	cellular response to dopamine
0.58	GO:0036499	PERK-mediated unfolded protein response
0.57	GO:1903204	negative regulation of oxidative stress-induced neuron death
0.57	GO:0010575	positive regulation of vascular endothelial growth factor production
0.56	GO:0042789	mRNA transcription by RNA polymerase II
0.56	GO:0045943	positive regulation of transcription by RNA polymerase I
0.56	GO:0043620	regulation of DNA-templated transcription in response to stress
0.56	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.56	GO:0043525	positive regulation of neuron apoptotic process

0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0043522	leucine zipper domain binding
0.55	GO:0001085	RNA polymerase II transcription factor binding
0.54	GO:0001046	core promoter sequence-specific DNA binding
0.52	GO:0019901	protein kinase binding
0.52	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.38	GO:0008022	protein C-terminus binding
0.36	GO:0046982	protein heterodimerization activity
0.34	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding

0.61	GO:0005634	nucleus
0.59	GO:1990037	Lewy body core
0.52	GO:0005813	centrosome
0.52	GO:0043005	neuron projection
0.51	GO:0005667	transcription factor complex
0.49	GO:0005737	cytoplasm
0.47	GO:0043233	organelle lumen
0.38	GO:0031256	leading edge membrane
0.38	GO:0031253	cell projection membrane
0.38	GO:0036477	somatodendritic compartment

sp|Q9W676|LDB2_CHICK
LIM domain-binding protein 2
Search

LDB2

0.94	LIM domain-binding protein 2

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.54	GO:0010669	epithelial structure maintenance
0.54	GO:0035019	somatic stem cell population maintenance
0.51	GO:0001942	hair follicle development
0.50	GO:0030334	regulation of cell migration
0.50	GO:0044089	positive regulation of cellular component biogenesis
0.49	GO:0043549	regulation of kinase activity
0.48	GO:0045893	positive regulation of transcription, DNA-templated
0.41	GO:1900108	negative regulation of nodal signaling pathway
0.40	GO:0090288	negative regulation of cellular response to growth factor stimulus

0.86	GO:0030274	LIM domain binding
0.75	GO:0000989	transcription factor activity, transcription factor binding
0.47	GO:0019899	enzyme binding
0.39	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.51	GO:0031252	cell leading edge
0.49	GO:0005667	transcription factor complex
0.46	GO:0031974	membrane-enclosed lumen
0.43	GO:0043232	intracellular non-membrane-bounded organelle
0.42	GO:0044446	intracellular organelle part
0.41	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9W689|ATX3_CHICK
Ataxin-3
Search

ATXN3

0.82	Ataxin-3 reference isoform

0.76	GO:0016579	protein deubiquitination
0.47	GO:0035640	exploration behavior
0.46	GO:0071218	cellular response to misfolded protein
0.46	GO:0010810	regulation of cell-substrate adhesion
0.45	GO:0034605	cellular response to heat
0.44	GO:0006515	protein quality control for misfolded or incompletely synthesized proteins
0.44	GO:0010498	proteasomal protein catabolic process
0.43	GO:0006511	ubiquitin-dependent protein catabolic process
0.40	GO:1904327	protein localization to cytosolic proteasome complex
0.39	GO:1904294	positive regulation of ERAD pathway

0.80	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.45	GO:0031625	ubiquitin protein ligase binding
0.39	GO:0051117	ATPase binding
0.38	GO:0061578	Lys63-specific deubiquitinase activity
0.38	GO:1990380	Lys48-specific deubiquitinase activity
0.36	GO:0042802	identical protein binding

0.47	GO:0042405	nuclear inclusion body
0.43	GO:0005759	mitochondrial matrix
0.40	GO:0005730	nucleolus
0.39	GO:0031966	mitochondrial membrane
0.36	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0005886	plasma membrane
0.36	GO:0005829	cytosol
0.34	GO:0016363	nuclear matrix
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|Q9W694|Q9W694_CHICK
Homeodomain transcription factor BARX2B
Search

BARX2

0.97	BARX homeobox 2

0.61	GO:0001502	cartilage condensation
0.58	GO:0014902	myotube differentiation
0.57	GO:0006366	transcription by RNA polymerase II
0.57	GO:0045944	positive regulation of transcription by RNA polymerase II
0.54	GO:0000122	negative regulation of transcription by RNA polymerase II
0.49	GO:0055123	digestive system development
0.49	GO:0048536	spleen development
0.48	GO:0007399	nervous system development
0.47	GO:0030178	negative regulation of Wnt signaling pathway
0.47	GO:0009952	anterior/posterior pattern specification

0.64	GO:0043565	sequence-specific DNA binding
0.60	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.58	GO:0001012	RNA polymerase II regulatory region DNA binding
0.55	GO:0003690	double-stranded DNA binding
0.54	GO:0003682	chromatin binding
0.33	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.53	GO:0005667	transcription factor complex
0.50	GO:0005829	cytosol
0.50	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part

tr|Q9W6A1|Q9W6A1_CHICK
Fibroblast growth factor
Search

FGF12

0.62	Fibroblast growth factor

0.83	GO:0008543	fibroblast growth factor receptor signaling pathway
0.75	GO:0010469	regulation of receptor activity
0.56	GO:1905150	regulation of voltage-gated sodium channel activity
0.55	GO:0098908	regulation of neuronal action potential
0.53	GO:0010765	positive regulation of sodium ion transport
0.52	GO:0050905	neuromuscular process
0.52	GO:0008344	adult locomotory behavior
0.49	GO:0007268	chemical synaptic transmission
0.39	GO:0003254	regulation of membrane depolarization
0.39	GO:2001258	negative regulation of cation channel activity

0.78	GO:0008083	growth factor activity
0.39	GO:0017080	sodium channel regulator activity
0.38	GO:0005104	fibroblast growth factor receptor binding
0.38	GO:0044325	ion channel binding
0.38	GO:0008201	heparin binding

0.43	GO:0005634	nucleus
0.34	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

sp|Q9W6D8|BARX1_CHICK
Homeobox protein BarH-like 1 (Fragment)
Search

BARX1

0.96	BARX homeobox 1

0.58	GO:0009888	tissue development
0.58	GO:0048536	spleen development
0.57	GO:0055123	digestive system development
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0030178	negative regulation of Wnt signaling pathway
0.55	GO:0010468	regulation of gene expression
0.55	GO:0009952	anterior/posterior pattern specification
0.55	GO:0030154	cell differentiation
0.53	GO:0006366	transcription by RNA polymerase II

0.63	GO:0043565	sequence-specific DNA binding
0.56	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.47	GO:0003682	chromatin binding
0.33	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.46	GO:0005667	transcription factor complex
0.44	GO:0005829	cytosol
0.43	GO:0043233	organelle lumen
0.40	GO:0044446	intracellular organelle part

tr|Q9W6E5|Q9W6E5_CHICK
SOUL protein
Search

0.82	Heme-binding protein 2

0.59

GO:0003777

microtubule motor activity

0.63

GO:0005871

kinesin complex

tr|Q9W6F2|Q9W6F2_CHICK
Protein A1
Search

0.78	GO:0043066	negative regulation of apoptotic process
0.49	GO:0001836	release of cytochrome c from mitochondria
0.48	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand
0.48	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.47	GO:0008053	mitochondrial fusion
0.46	GO:0043065	positive regulation of apoptotic process
0.38	GO:0055085	transmembrane transport

0.44	GO:0042803	protein homodimerization activity
0.44	GO:0046982	protein heterodimerization activity
0.42	GO:0022803	passive transmembrane transporter activity
0.34	GO:0016874	ligase activity

0.45	GO:0005741	mitochondrial outer membrane
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016874

sp|Q9W6H0|MIME_CHICK
Mimecan
Search

OGN

0.97	Osteoglycin OG

0.60	GO:0007409	axonogenesis
0.49	GO:0010469	regulation of receptor activity
0.42	GO:0048662	negative regulation of smooth muscle cell proliferation
0.40	GO:0042340	keratan sulfate catabolic process
0.40	GO:0018146	keratan sulfate biosynthetic process
0.34	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.34	GO:0006418	tRNA aminoacylation for protein translation
0.33	GO:0018108	peptidyl-tyrosine phosphorylation

0.50	GO:0008083	growth factor activity
0.35	GO:0005201	extracellular matrix structural constituent
0.34	GO:0002161	aminoacyl-tRNA editing activity
0.34	GO:0000049	tRNA binding
0.34	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.33	GO:0046872	metal ion binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004713	protein tyrosine kinase activity

0.73	GO:0031012	extracellular matrix
0.71	GO:0005615	extracellular space
0.40	GO:1903561	extracellular vesicle
0.39	GO:0043202	lysosomal lumen
0.39	GO:0005796	Golgi lumen
0.36	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:6.1

GO:0016875

sp|Q9W6I1|RBPS2_CHICK
RNA-binding protein with multiple splicing 2
Search

RBPMS2

0.92	RNA-binding protein with multiple splicing

0.54	GO:0051151	negative regulation of smooth muscle cell differentiation
0.48	GO:0060391	positive regulation of SMAD protein import into nucleus
0.47	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.44	GO:0000398	mRNA splicing, via spliceosome
0.42	GO:0006979	response to oxidative stress
0.39	GO:0048557	embryonic digestive tract morphogenesis
0.39	GO:0048661	positive regulation of smooth muscle cell proliferation
0.39	GO:0030514	negative regulation of BMP signaling pathway
0.38	GO:0090259	regulation of retinal ganglion cell axon guidance
0.38	GO:0031290	retinal ganglion cell axon guidance

0.64	GO:0042803	protein homodimerization activity
0.58	GO:0003723	RNA binding
0.45	GO:0003713	transcription coactivator activity
0.34	GO:0008073	ornithine decarboxylase inhibitor activity

0.46	GO:0005685	U1 snRNP
0.44	GO:0010494	cytoplasmic stress granule
0.41	GO:0005654	nucleoplasm
0.41	GO:0005829	cytosol
0.35	GO:0000932	P-body

tr|Q9W6I3|Q9W6I3_CHICK
Substance P receptor
Search

TACR1

0.97	Neuromedin-K receptor

0.85	GO:0007217	tachykinin receptor signaling pathway
0.62	GO:1902093	positive regulation of flagellated sperm motility
0.55	GO:0070472	regulation of uterine smooth muscle contraction
0.53	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.52	GO:0048265	response to pain
0.48	GO:0045987	positive regulation of smooth muscle contraction
0.43	GO:0007268	chemical synaptic transmission
0.43	GO:0072347	response to anesthetic
0.43	GO:0043279	response to alkaloid
0.42	GO:0060359	response to ammonium ion

0.86	GO:0004995	tachykinin receptor activity
0.34	GO:0050254	rhodopsin kinase activity
0.34	GO:0005515	protein binding

0.61	GO:0097225	sperm midpiece
0.57	GO:0061827	sperm head
0.56	GO:0005886	plasma membrane
0.39	GO:0030425	dendrite
0.39	GO:0044297	cell body
0.36	GO:0009986	cell surface
0.36	GO:0031252	cell leading edge
0.34	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.34

EC:2.7.11.14

GO:0050254

tr|Q9W6J2|Q9W6J2_CHICK
Glutathione S-transferase class-alpha
Search

0.43	Glutathione S-transferase class-alpha

0.44	GO:0043390	aflatoxin B1 metabolic process
0.41	GO:0006749	glutathione metabolic process
0.40	GO:0009636	response to toxic substance
0.39	GO:0043651	linoleic acid metabolic process
0.39	GO:0030855	epithelial cell differentiation
0.37	GO:0070887	cellular response to chemical stimulus
0.37	GO:1901685	glutathione derivative metabolic process
0.37	GO:0010226	response to lithium ion
0.36	GO:0010043	response to zinc ion
0.35	GO:0009410	response to xenobiotic stimulus

0.76	GO:0004364	glutathione transferase activity
0.37	GO:0004602	glutathione peroxidase activity
0.36	GO:0043295	glutathione binding
0.34	GO:0005515	protein binding
0.33	GO:0008144	drug binding

0.42	GO:0005829	cytosol
0.36	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.34	GO:0005739	mitochondrion

0.76

EC:2.5.1.18

GO:0004364

sp|Q9W6S3|SIN1_CHICK
Target of rapamycin complex 2 subunit MAPKAP1
Search

MAPKAP1

0.95	Mitogen-activated protein kinase associated protein 1

0.57	GO:0046580	negative regulation of Ras protein signal transduction
0.50	GO:0038203	TORC2 signaling
0.50	GO:0090133	mesendoderm migration
0.49	GO:0030950	establishment or maintenance of actin cytoskeleton polarity
0.48	GO:0031098	stress-activated protein kinase signaling cascade
0.47	GO:0042074	cell migration involved in gastrulation
0.45	GO:0060491	regulation of cell projection assembly
0.40	GO:0016310	phosphorylation
0.38	GO:0021762	substantia nigra development
0.36	GO:0032148	activation of protein kinase B activity

0.59	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.59	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.59	GO:0070300	phosphatidic acid binding
0.58	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.57	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.54	GO:0019901	protein kinase binding
0.52	GO:0017016	Ras GTPase binding
0.41	GO:0016301	kinase activity

0.82	GO:0031932	TORC2 complex
0.51	GO:0005794	Golgi apparatus
0.49	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.44	GO:0005886	plasma membrane
0.39	GO:0031410	cytoplasmic vesicle

sp|Q9W6U8|MEF2A_CHICK
Myocyte-specific enhancer factor 2A
Search

MEF2A

0.94	Myocyte-specific enhancer factor 2A

0.72	GO:0045944	positive regulation of transcription by RNA polymerase II
0.59	GO:0070375	ERK5 cascade
0.58	GO:0055005	ventricular cardiac myofibril assembly
0.56	GO:0006351	transcription, DNA-templated
0.56	GO:0014742	positive regulation of muscle hypertrophy
0.55	GO:0061337	cardiac conduction
0.55	GO:0071277	cellular response to calcium ion
0.55	GO:0010611	regulation of cardiac muscle hypertrophy
0.54	GO:0048311	mitochondrion distribution
0.53	GO:0000002	mitochondrial genome maintenance

0.74	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.66	GO:0046983	protein dimerization activity
0.56	GO:0035035	histone acetyltransferase binding
0.55	GO:0033613	activating transcription factor binding
0.55	GO:0042826	histone deacetylase binding
0.55	GO:0046332	SMAD binding
0.54	GO:0001105	RNA polymerase II transcription coactivator activity
0.54	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.53	GO:0001085	RNA polymerase II transcription factor binding
0.52	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.60	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.48	GO:0000785	chromatin
0.47	GO:0005829	cytosol
0.47	GO:0043233	organelle lumen
0.30	GO:0016020	membrane

tr|Q9W6U9|Q9W6U9_CHICK
Glycoprotein 130
Search

IL6ST

0.97	Interleukin-6 receptor subunit beta

0.76	GO:0019221	cytokine-mediated signaling pathway
0.62	GO:0048861	leukemia inhibitory factor signaling pathway
0.60	GO:0048711	positive regulation of astrocyte differentiation
0.60	GO:0071354	cellular response to interleukin-6
0.59	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.59	GO:0045669	positive regulation of osteoblast differentiation
0.58	GO:0042102	positive regulation of T cell proliferation
0.57	GO:0008593	regulation of Notch signaling pathway
0.53	GO:0005977	glycogen metabolic process
0.40	GO:0070104	negative regulation of interleukin-6-mediated signaling pathway

0.78	GO:0004896	cytokine receptor activity
0.63	GO:0019981	interleukin-6 binding
0.63	GO:0019970	interleukin-11 binding
0.62	GO:0005127	ciliary neurotrophic factor receptor binding
0.61	GO:0005138	interleukin-6 receptor binding
0.35	GO:0046983	protein dimerization activity
0.34	GO:0042802	identical protein binding

0.62	GO:0005900	oncostatin-M receptor complex
0.62	GO:0005896	interleukin-6 receptor complex
0.62	GO:0070110	ciliary neurotrophic factor receptor complex
0.56	GO:0009897	external side of plasma membrane
0.56	GO:0043025	neuronal cell body
0.56	GO:0030425	dendrite
0.37	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:0044298	cell body membrane

sp|Q9W6V2|NEGR1_CHICK
Neuronal growth regulator 1
Search

NEGR1

0.97	Neuronal growth regulator 1

0.69	GO:0007626	locomotory behavior
0.65	GO:0007631	feeding behavior
0.64	GO:0010976	positive regulation of neuron projection development
0.60	GO:0098609	cell-cell adhesion
0.53	GO:0035640	exploration behavior
0.40	GO:0006501	C-terminal protein lipidation

0.43

GO:0042802

identical protein binding

0.48	GO:0031225	anchored component of membrane
0.48	GO:0005886	plasma membrane
0.47	GO:0005829	cytosol
0.40	GO:0070062	extracellular exosome
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.30	GO:0016021	integral component of membrane

sp|Q9W6V5|PTPRJ_CHICK
Receptor-type tyrosine-protein phosphatase eta
Search

PTPRJ

0.96	Protein tyrosine phosphatase, receptor type J

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.70	GO:0043116	negative regulation of vascular permeability
0.70	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway
0.70	GO:0050860	negative regulation of T cell receptor signaling pathway
0.69	GO:0051894	positive regulation of focal adhesion assembly
0.68	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.68	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.68	GO:0051898	negative regulation of protein kinase B signaling
0.68	GO:0050918	positive chemotaxis
0.67	GO:0051897	positive regulation of protein kinase B signaling

0.75	GO:0004725	protein tyrosine phosphatase activity
0.72	GO:0070097	delta-catenin binding
0.71	GO:0045295	gamma-catenin binding
0.69	GO:0005161	platelet-derived growth factor receptor binding
0.69	GO:0051019	mitogen-activated protein kinase binding
0.65	GO:0008013	beta-catenin binding

0.68	GO:0001772	immunological synapse
0.61	GO:0005911	cell-cell junction
0.60	GO:0009986	cell surface
0.43	GO:0032587	ruffle membrane
0.42	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.75

GO:0004725

sp|Q9W6V6|TEN1_CHICK
Teneurin-1
Search

TENM1

0.91	Teneurin transmembrane protein 1

0.77	GO:0048666	neuron development
0.57	GO:0007165	signal transduction
0.50	GO:0097264	self proteolysis
0.48	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.44	GO:0000902	cell morphogenesis
0.38	GO:0051491	positive regulation of filopodium assembly
0.38	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.38	GO:0090316	positive regulation of intracellular protein transport
0.37	GO:0006359	regulation of transcription by RNA polymerase III
0.37	GO:0043406	positive regulation of MAP kinase activity

0.49	GO:0042803	protein homodimerization activity
0.48	GO:0046982	protein heterodimerization activity
0.46	GO:0050839	cell adhesion molecule binding
0.36	GO:0005509	calcium ion binding
0.35	GO:0008201	heparin binding
0.30	GO:0003824	catalytic activity

0.45	GO:0005887	integral component of plasma membrane
0.45	GO:0043005	neuron projection
0.38	GO:0016363	nuclear matrix
0.37	GO:0016607	nuclear speck
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005794	Golgi apparatus
0.36	GO:0005783	endoplasmic reticulum
0.36	GO:0005856	cytoskeleton
0.34	GO:0005576	extracellular region

sp|Q9W719|HPRT_CHICK
Hypoxanthine-guanine phosphoribosyltransferase
Search

HPRT1

0.50	Hypoxanthine-guanine phosphoribosyltransferase

0.78	GO:0032264	IMP salvage
0.75	GO:0006166	purine ribonucleoside salvage
0.58	GO:0046038	GMP catabolic process
0.58	GO:0006178	guanine salvage
0.58	GO:0045964	positive regulation of dopamine metabolic process
0.54	GO:0051289	protein homotetramerization
0.54	GO:0007625	grooming behavior
0.54	GO:0046100	hypoxanthine metabolic process
0.54	GO:0021756	striatum development
0.54	GO:0001975	response to amphetamine

0.79	GO:0004422	hypoxanthine phosphoribosyltransferase activity
0.79	GO:0052657	guanine phosphoribosyltransferase activity
0.53	GO:0046872	metal ion binding
0.52	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.50	GO:0042803	protein homodimerization activity

0.48	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.33	GO:0005694	chromosome

0.79	EC:2.4.2.8	GO:0004422
0.79	KEGG:R01132	GO:0004422

sp|Q9W734|SMAD6_CHICK
Mothers against decapentaplegic homolog 6
Search

0.58	Mothers against decapentaplegic homolog

0.71	GO:0007179	transforming growth factor beta receptor signaling pathway
0.56	GO:0006355	regulation of transcription, DNA-templated
0.51	GO:0006351	transcription, DNA-templated
0.48	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.48	GO:0090288	negative regulation of cellular response to growth factor stimulus
0.46	GO:0034616	response to laminar fluid shear stress
0.46	GO:0051241	negative regulation of multicellular organismal process
0.45	GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation
0.45	GO:0007352	zygotic specification of dorsal/ventral axis
0.45	GO:0003281	ventricular septum development

0.54	GO:0003700	DNA binding transcription factor activity
0.49	GO:0003677	DNA binding
0.47	GO:0030617	transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
0.46	GO:0070411	I-SMAD binding
0.46	GO:0034713	type I transforming growth factor beta receptor binding
0.46	GO:0070698	type I activin receptor binding
0.45	GO:0070410	co-SMAD binding
0.44	GO:0070412	R-SMAD binding
0.44	GO:0001067	regulatory region nucleic acid binding
0.43	GO:0031625	ubiquitin protein ligase binding

0.64	GO:0005667	transcription factor complex
0.54	GO:0005634	nucleus
0.44	GO:0005737	cytoplasm
0.42	GO:0012505	endomembrane system
0.40	GO:0070013	intracellular organelle lumen
0.39	GO:0097708	intracellular vesicle
0.38	GO:0044446	intracellular organelle part
0.37	GO:0016342	catenin complex
0.37	GO:0005913	cell-cell adherens junction
0.35	GO:0015630	microtubule cytoskeleton

sp|Q9W757|SOX10_CHICK
Transcription factor SOX-10
Search

SOX10

0.97	LOW QUALITY PROTEIN: transcription factor SOX-10

0.57	GO:0032808	lacrimal gland development
0.56	GO:0048709	oligodendrocyte differentiation
0.56	GO:0030318	melanocyte differentiation
0.56	GO:0014033	neural crest cell differentiation
0.56	GO:0048484	enteric nervous system development
0.56	GO:0032291	axon ensheathment in central nervous system
0.55	GO:0014031	mesenchymal cell development
0.55	GO:0048864	stem cell development
0.55	GO:0021782	glial cell development
0.55	GO:0002052	positive regulation of neuroblast proliferation

0.55	GO:0001158	enhancer sequence-specific DNA binding
0.55	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.53	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.51	GO:0003682	chromatin binding
0.51	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0042802	identical protein binding
0.48	GO:0008134	transcription factor binding
0.39	GO:0001046	core promoter sequence-specific DNA binding
0.38	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0097157	pre-mRNA intronic binding

0.61	GO:0005634	nucleus
0.55	GO:0031315	extrinsic component of mitochondrial outer membrane
0.46	GO:0070013	intracellular organelle lumen
0.37	GO:0000785	chromatin
0.35	GO:0005667	transcription factor complex
0.30	GO:0016021	integral component of membrane

sp|Q9W770|SPON1_CHICK
Spondin-1
Search

SPON1

0.68	F-spondin extracellular matrix protein

0.36

GO:0007155

cell adhesion

0.33

GO:0046872

metal ion binding

0.76	GO:0005578	proteinaceous extracellular matrix
0.41	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

sp|Q9W7C5|HBEGF_CHICK
Proheparin-binding EGF-like growth factor
Search

HBEGF

0.97	Heparin binding EGF like growth factor

0.59	GO:0051549	positive regulation of keratinocyte migration
0.59	GO:0035313	wound healing, spreading of epidermal cells
0.58	GO:0007173	epidermal growth factor receptor signaling pathway
0.57	GO:0090303	positive regulation of wound healing
0.57	GO:0048661	positive regulation of smooth muscle cell proliferation
0.56	GO:0051897	positive regulation of protein kinase B signaling
0.55	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.55	GO:0008016	regulation of heart contraction
0.55	GO:0060326	cell chemotaxis
0.53	GO:0010469	regulation of receptor activity

0.58	GO:0005154	epidermal growth factor receptor binding
0.56	GO:0008201	heparin binding
0.54	GO:0008083	growth factor activity
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0051082	unfolded protein binding
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0004713	protein tyrosine kinase activity

0.52	GO:0005615	extracellular space
0.52	GO:0009986	cell surface
0.48	GO:0005887	integral component of plasma membrane
0.35	GO:0016272	prefoldin complex
0.35	GO:0030669	clathrin-coated endocytic vesicle membrane

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|Q9W7I5|RBBP4_CHICK
Histone-binding protein RBBP4
Search

RBBP4

0.88	RB binding protein 4, chromatin remodeling factor

0.49	GO:0006335	DNA replication-dependent nucleosome assembly
0.47	GO:0006336	DNA replication-independent nucleosome assembly
0.46	GO:0006338	chromatin remodeling
0.40	GO:0016569	covalent chromatin modification
0.39	GO:0006260	DNA replication
0.38	GO:0007049	cell cycle
0.38	GO:0060416	response to growth hormone
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.47	GO:0042826	histone deacetylase binding
0.43	GO:0008094	DNA-dependent ATPase activity
0.36	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.36	GO:0031492	nucleosomal DNA binding
0.36	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0004407	histone deacetylase activity
0.34	GO:0042393	histone binding

0.61	GO:0005634	nucleus
0.52	GO:0033186	CAF-1 complex
0.48	GO:0034708	methyltransferase complex
0.46	GO:0017053	transcriptional repressor complex
0.44	GO:0031974	membrane-enclosed lumen
0.43	GO:0000785	chromatin
0.42	GO:0005829	cytosol
0.41	GO:1904949	ATPase complex

0.34

GO:0004407

tr|Q9W7K9|Q9W7K9_CHICK
SOCS box-containing WD protein SWiP-1
Search

WSB1

0.96	WD repeat and SOCS box-containing protein 1

0.65	GO:0016567	protein ubiquitination
0.59	GO:0035556	intracellular signal transduction
0.35	GO:0043687	post-translational protein modification

0.37	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0005515	protein binding

0.44

GO:0005622

intracellular

0.37

GO:0004842

sp|Q9W7R5|SOX21_CHICK
Transcription factor SOX-21
Search

SOXB2

0.84	SOX domain-containing protein dichaete

0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.51	GO:0048731	system development
0.49	GO:0048863	stem cell differentiation
0.48	GO:0051254	positive regulation of RNA metabolic process
0.48	GO:0010557	positive regulation of macromolecule biosynthetic process
0.48	GO:0031328	positive regulation of cellular biosynthetic process
0.47	GO:0022405	hair cycle process
0.47	GO:0009888	tissue development

0.55	GO:0003677	DNA binding
0.49	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.49	GO:0001067	regulatory region nucleic acid binding
0.40	GO:0035198	miRNA binding
0.36	GO:0003682	chromatin binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0005515	protein binding
0.32	GO:0030554	adenyl nucleotide binding

0.61	GO:0005634	nucleus
0.37	GO:0005829	cytosol
0.37	GO:0070013	intracellular organelle lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.34

EC:1.3.1.74

GO:0032440

sp|Q9W7R6|SOX14_CHICK
Transcription factor SOX-14
Search

SOX14

0.94	Transcription factor SOX-14

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.52	GO:0009649	entrainment of circadian clock
0.52	GO:2001222	regulation of neuron migration
0.49	GO:0007601	visual perception
0.45	GO:0021854	hypothalamus development
0.38	GO:1902679	negative regulation of RNA biosynthetic process
0.36	GO:0006351	transcription, DNA-templated
0.33	GO:0007219	Notch signaling pathway

0.54	GO:0003677	DNA binding
0.48	GO:0003682	chromatin binding
0.47	GO:0046982	protein heterodimerization activity
0.46	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.33	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.32	GO:0005509	calcium ion binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.41	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

EC:1.3.1.74

GO:0032440

sp|Q9YGC1|BLNK_CHICK
B-cell linker protein
Search

BLNK

0.93	B-cell linker protein isoform B

0.76	GO:0009967	positive regulation of signal transduction
0.63	GO:0035556	intracellular signal transduction
0.58	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.56	GO:0006955	immune response
0.52	GO:0007202	activation of phospholipase C activity
0.50	GO:0030183	B cell differentiation
0.46	GO:0051726	regulation of cell cycle

0.85	GO:0005070	SH3/SH2 adaptor activity
0.67	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity

0.77	GO:0036464	cytoplasmic ribonucleoprotein granule
0.55	GO:0005886	plasma membrane
0.44	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q9YGI5|DNAS1_CHICK
Deoxyribonuclease-1
Search

DNASE1

0.64	Deoxyribonuclease

0.76	GO:0006308	DNA catabolic process
0.58	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.54	GO:0070948	regulation of neutrophil mediated cytotoxicity
0.53	GO:0002283	neutrophil activation involved in immune response
0.52	GO:0002673	regulation of acute inflammatory response
0.52	GO:0003335	corneocyte development
0.48	GO:0001942	hair follicle development
0.41	GO:0006915	apoptotic process
0.35	GO:0002088	lens development in camera-type eye
0.35	GO:0060041	retina development in camera-type eye

0.71	GO:0004536	deoxyribonuclease activity
0.60	GO:0004519	endonuclease activity
0.40	GO:0003779	actin binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0003677	DNA binding

0.42	GO:0005634	nucleus
0.39	GO:0005576	extracellular region
0.39	GO:0012505	endomembrane system
0.37	GO:0031967	organelle envelope
0.35	GO:0031982	vesicle
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q9YGL6|PALM_CHICK
Paralemmin-1
Search

PALM

0.97	Paralemmin

0.69	GO:0008360	regulation of cell shape
0.59	GO:0071257	cellular response to electrical stimulus
0.59	GO:0060074	synapse maturation
0.58	GO:0060160	negative regulation of dopamine receptor signaling pathway
0.58	GO:0007194	negative regulation of adenylate cyclase activity
0.58	GO:0051491	positive regulation of filopodium assembly
0.56	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.55	GO:0072659	protein localization to plasma membrane
0.50	GO:0007010	cytoskeleton organization
0.44	GO:0060999	positive regulation of dendritic spine development

0.62	GO:0031750	D3 dopamine receptor binding
0.34	GO:0016301	kinase activity

0.58	GO:0031527	filopodium membrane
0.57	GO:0044309	neuron spine
0.57	GO:0014069	postsynaptic density
0.44	GO:0005634	nucleus
0.44	GO:0016327	apicolateral plasma membrane
0.43	GO:0097060	synaptic membrane
0.43	GO:0016323	basolateral plasma membrane
0.42	GO:0030425	dendrite
0.42	GO:0030424	axon
0.41	GO:0044306	neuron projection terminus

sp|Q9YGL7|PIT1_CHICK
Pituitary-specific positive transcription factor 1
Search

PIT-1

0.57	Pituitary-specific positive transcription factor 1

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0060133	somatotropin secreting cell development
0.55	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process
0.55	GO:0001708	cell fate specification
0.53	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.52	GO:0040018	positive regulation of multicellular organism growth
0.52	GO:0030183	B cell differentiation

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0001105	RNA polymerase II transcription coactivator activity
0.53	GO:0001102	RNA polymerase II activating transcription factor binding
0.48	GO:0003682	chromatin binding
0.37	GO:0044212	transcription regulatory region DNA binding
0.36	GO:0003714	transcription corepressor activity
0.36	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.48	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|Q9YGL9|AT2A3_CHICK
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3
Search

ATP2A3

0.56	Calcium-transporting ATPase

0.76	GO:0070588	calcium ion transmembrane transport
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.40	GO:0008016	regulation of heart contraction
0.39	GO:0032470	positive regulation of endoplasmic reticulum calcium ion concentration
0.38	GO:1903233	regulation of calcium ion-dependent exocytosis of neurotransmitter
0.38	GO:0033292	T-tubule organization
0.38	GO:0014883	transition between fast and slow fiber
0.38	GO:0070296	sarcoplasmic reticulum calcium ion transport
0.38	GO:0003299	muscle hypertrophy in response to stress
0.38	GO:0014887	cardiac muscle adaptation

0.80	GO:0005388	calcium-transporting ATPase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0044548	S100 protein binding
0.36	GO:0019899	enzyme binding
0.35	GO:0005509	calcium ion binding

0.75	GO:0033017	sarcoplasmic reticulum membrane
0.38	GO:0097470	ribbon synapse
0.36	GO:0044428	nuclear part
0.35	GO:0031095	platelet dense tubular network membrane
0.35	GO:0043233	organelle lumen
0.33	GO:0031967	organelle envelope
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:3.6.3.8

GO:0005388

sp|Q9YGQ1|EF1B_CHICK
Elongation factor 1-beta
Search

EEF1B2

0.66	Eukaryotic translation elongation factor 1 beta 2

0.70	GO:0006414	translational elongation
0.36	GO:0045471	response to ethanol
0.34	GO:0071479	cellular response to ionizing radiation

0.71	GO:0003746	translation elongation factor activity
0.34	GO:0005515	protein binding

0.84	GO:0005853	eukaryotic translation elongation factor 1 complex
0.44	GO:0005783	endoplasmic reticulum
0.34	GO:0005634	nucleus
0.34	GO:0005829	cytosol
0.33	GO:0043233	organelle lumen
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044446	intracellular organelle part

sp|Q9YGS0|IRX4_CHICK
Iroquois-class homeodomain protein IRX-4
Search

IRX4

0.87	Iroquois homeobox 4

0.63	GO:0048513	animal organ development
0.59	GO:0072359	circulatory system development
0.58	GO:0048916	posterior lateral line development
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0035315	hair cell differentiation
0.56	GO:0042490	mechanoreceptor differentiation
0.56	GO:0042461	photoreceptor cell development
0.38	GO:0048560	establishment of anatomical structure orientation

0.65

GO:0043565

sequence-specific DNA binding

0.61

GO:0005634

nucleus

sp|Q9YGV8|TBPL1_CHICK
TATA box-binding protein-like protein 1
Search

TBPL1

0.96	TATA-box binding protein like 1

0.69	GO:0006352	DNA-templated transcription, initiation
0.57	GO:0001675	acrosome assembly
0.56	GO:0007289	spermatid nucleus differentiation
0.54	GO:0006366	transcription by RNA polymerase II
0.51	GO:0006235	dTTP biosynthetic process
0.51	GO:0045944	positive regulation of transcription by RNA polymerase II
0.42	GO:0009792	embryo development ending in birth or egg hatching
0.33	GO:0006413	translational initiation
0.32	GO:0055114	oxidation-reduction process

0.55	GO:0003677	DNA binding
0.55	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0005515	protein binding
0.34	GO:0003713	transcription coactivator activity
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0003743	translation initiation factor activity
0.32	GO:0008270	zinc ion binding

0.54	GO:0005672	transcription factor TFIIA complex
0.39	GO:0005737	cytoplasm
0.33	GO:0031514	motile cilium

0.34

EC:1.3.1.74

GO:0032440

tr|Q9YGW6|Q9YGW6_CHICK
Ezrin
Search

EZR

0.97	Epididymis secretory protein Li 105

0.58	GO:1902965	regulation of protein localization to early endosome
0.58	GO:2000643	positive regulation of early endosome to late endosome transport
0.58	GO:1905668	positive regulation of protein localization to endosome
0.56	GO:0061028	establishment of endothelial barrier
0.56	GO:0022614	membrane to membrane docking
0.54	GO:0030033	microvillus assembly
0.54	GO:0007159	leukocyte cell-cell adhesion
0.53	GO:0035088	establishment or maintenance of apical/basal cell polarity
0.53	GO:1902115	regulation of organelle assembly
0.53	GO:1900041	negative regulation of interleukin-2 secretion

0.73	GO:0003779	actin binding
0.53	GO:0050839	cell adhesion molecule binding
0.53	GO:0051117	ATPase binding
0.51	GO:0034236	protein kinase A catalytic subunit binding
0.51	GO:0044548	S100 protein binding
0.51	GO:0034237	protein kinase A regulatory subunit binding
0.50	GO:0097718	disordered domain specific binding
0.49	GO:0008022	protein C-terminus binding
0.47	GO:0032403	protein complex binding
0.46	GO:0008017	microtubule binding

0.69	GO:0005856	cytoskeleton
0.55	GO:0005902	microvillus
0.55	GO:0071437	invadopodium
0.54	GO:0030175	filopodium
0.54	GO:0001931	uropod
0.54	GO:0016324	apical plasma membrane
0.53	GO:0005925	focal adhesion
0.53	GO:0043209	myelin sheath
0.52	GO:0001726	ruffle
0.51	GO:0098862	cluster of actin-based cell projections

0.33

GO:0004714

sp|Q9YGX2|RPE65_CHICK
Retinoid isomerohydrolase
Search

RPE65

0.97	Retinal Mueller cells isomerohydrolase

0.66	GO:0001523	retinoid metabolic process
0.61	GO:1901827	zeaxanthin biosynthetic process
0.61	GO:0034308	primary alcohol metabolic process
0.61	GO:0034754	cellular hormone metabolic process
0.56	GO:0007468	regulation of rhodopsin gene expression
0.56	GO:0050908	detection of light stimulus involved in visual perception
0.56	GO:0071257	cellular response to electrical stimulus
0.55	GO:0001895	retina homeostasis
0.53	GO:0008286	insulin receptor signaling pathway
0.53	GO:0060042	retina morphogenesis in camera-type eye

0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.71	GO:0052885	all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity
0.68	GO:1901612	cardiolipin binding
0.66	GO:0031210	phosphatidylcholine binding
0.66	GO:0001786	phosphatidylserine binding
0.60	GO:0004744	retinal isomerase activity
0.53	GO:0046872	metal ion binding
0.49	GO:0052884	all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity
0.36	GO:0050251	retinol isomerase activity
0.34	GO:0005515	protein binding

0.39	GO:0005783	endoplasmic reticulum
0.37	GO:0031090	organelle membrane
0.37	GO:0044297	cell body
0.37	GO:0005886	plasma membrane
0.33	GO:0005829	cytosol

0.75	EC:1.13.11	GO:0016702
0.71	KEGG:R08388	GO:0052885

tr|Q9YGX6|Q9YGX6_CHICK
Protein Wnt
Search

tr|Q9YGX8|Q9YGX8_CHICK
Potassium channel Shaker cKv1.4
Search

KCNA4

0.97	Potassium channel shaker alpha subunit pKv 1.4

0.77	GO:0051260	protein homooligomerization
0.77	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport

0.78	GO:0005249	voltage-gated potassium channel activity
0.66	GO:0030955	potassium ion binding
0.35	GO:0005515	protein binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.46	GO:0030424	axon
0.36	GO:0098889	intrinsic component of presynaptic membrane
0.35	GO:0098936	intrinsic component of postsynaptic membrane
0.35	GO:0099699	integral component of synaptic membrane
0.35	GO:0045121	membrane raft
0.35	GO:0043198	dendritic shaft
0.35	GO:0043197	dendritic spine
0.35	GO:0032279	asymmetric synapse
0.34	GO:0009986	cell surface

sp|Q9YH06|HMGB1_CHICK
High mobility group protein B1
Search

HMGB1

0.87	High mobility group box 1

0.58	GO:0032392	DNA geometric change
0.57	GO:0051103	DNA ligation involved in DNA repair
0.51	GO:0097350	neutrophil clearance
0.51	GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.51	GO:0002643	regulation of tolerance induction
0.51	GO:0050716	positive regulation of interleukin-1 secretion
0.51	GO:1990774	tumor necrosis factor secretion
0.51	GO:0032072	regulation of restriction endodeoxyribonuclease activity
0.50	GO:0035711	T-helper 1 cell activation
0.50	GO:0032425	positive regulation of mismatch repair

0.72	GO:0097100	supercoiled DNA binding
0.71	GO:0000405	bubble DNA binding
0.69	GO:0008301	DNA binding, bending
0.69	GO:0000400	four-way junction DNA binding
0.49	GO:0019958	C-X-C chemokine binding
0.48	GO:0001786	phosphatidylserine binding
0.48	GO:0070182	DNA polymerase binding
0.47	GO:0070491	repressing transcription factor binding
0.47	GO:0005178	integrin binding
0.46	GO:0001530	lipopolysaccharide binding

0.59	GO:0005634	nucleus
0.50	GO:0035868	alphav-beta3 integrin-HMGB1 complex
0.47	GO:0005694	chromosome
0.46	GO:0017053	transcriptional repressor complex
0.45	GO:0005768	endosome
0.45	GO:0005615	extracellular space
0.45	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.44	GO:0009986	cell surface
0.42	GO:0070013	intracellular organelle lumen
0.41	GO:0043005	neuron projection

0.40

GO:0016829

sp|Q9YH13|HXC8_CHICK
Homeobox protein Hox-C8
Search

HOXC8

0.95	Homeobox protein pXhoxc8

0.66	GO:0007275	multicellular organism development
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0009653	anatomical structure morphogenesis
0.50	GO:1902679	negative regulation of RNA biosynthetic process
0.48	GO:0030154	cell differentiation
0.44	GO:0007625	grooming behavior
0.43	GO:0019233	sensory perception of pain
0.43	GO:0045638	negative regulation of myeloid cell differentiation

0.63	GO:0043565	sequence-specific DNA binding
0.59	GO:0003700	DNA binding transcription factor activity

0.60	GO:0005634	nucleus
0.49	GO:0031974	membrane-enclosed lumen
0.48	GO:0015630	microtubule cytoskeleton
0.44	GO:0044446	intracellular organelle part

tr|Q9YH14|Q9YH14_CHICK
Progesterone receptor binding protein
Search

ATP5I

0.84	Mitochondrial ATP synthase subunit e

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.37	GO:0001666	response to hypoxia
0.37	GO:0042407	cristae formation
0.36	GO:0006839	mitochondrial transport
0.35	GO:0046907	intracellular transport

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.46	GO:0016887	ATPase activity
0.39	GO:0033142	progesterone receptor binding
0.39	GO:0047624	adenosine-tetraphosphatase activity
0.37	GO:0031490	chromatin DNA binding

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.36	GO:0000790	nuclear chromatin
0.36	GO:0032993	protein-DNA complex
0.30	GO:0016021	integral component of membrane

0.46

GO:0016887

sp|Q9YH18|QKI_CHICK
Protein quaking
Search

QKI

0.96	Quaking homolog, KH domain RNA binding

0.46	GO:0061158	3'-UTR-mediated mRNA destabilization
0.45	GO:0030154	cell differentiation
0.45	GO:0042759	long-chain fatty acid biosynthetic process
0.45	GO:0007275	multicellular organism development
0.44	GO:0051028	mRNA transport
0.44	GO:0008380	RNA splicing
0.43	GO:0007283	spermatogenesis
0.43	GO:0061061	muscle structure development
0.43	GO:0022412	cellular process involved in reproduction in multicellular organism
0.42	GO:0003006	developmental process involved in reproduction

0.59	GO:0003723	RNA binding
0.45	GO:0017124	SH3 domain binding

0.42	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm

tr|Q9YH27|Q9YH27_CHICK
Homeobox protein Hox-B8
Search

HOXB8

0.87	Homeobox protein Hox-B8

0.68	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0007625	grooming behavior
0.53	GO:0019233	sensory perception of pain
0.53	GO:0045638	negative regulation of myeloid cell differentiation
0.53	GO:0008344	adult locomotory behavior
0.52	GO:0009653	anatomical structure morphogenesis
0.51	GO:1902679	negative regulation of RNA biosynthetic process

0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.34	GO:0001012	RNA polymerase II regulatory region DNA binding
0.34	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.43	GO:0015630	microtubule cytoskeleton

tr|Q9YH55|Q9YH55_CHICK
Olfactory receptor
Search

0.46	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9YH58|FTCD_CHICK
Formimidoyltransferase-cyclodeaminase
Search

FTCD

0.80	Formimidoyltransferase-cyclodeaminase

0.39	GO:0019557	histidine catabolic process to glutamate and formate
0.39	GO:0043606	formamide metabolic process
0.39	GO:0035999	tetrahydrofolate interconversion
0.36	GO:0007010	cytoskeleton organization
0.33	GO:0006352	DNA-templated transcription, initiation
0.33	GO:0015074	DNA integration
0.33	GO:0006310	DNA recombination

0.84	GO:0005542	folic acid binding
0.51	GO:0016740	transferase activity
0.49	GO:0008017	microtubule binding
0.43	GO:0030412	formimidoyltetrahydrofolate cyclodeaminase activity
0.35	GO:0019215	intermediate filament binding
0.33	GO:0016866	intramolecular transferase activity
0.33	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity
0.32	GO:0003677	DNA binding

0.57	GO:0030868	smooth endoplasmic reticulum membrane
0.52	GO:0005794	Golgi apparatus
0.47	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.40	GO:0005814	centriole
0.38	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.51	EC:2	GO:0016740
0.43	KEGG:R02302	GO:0030412

tr|Q9YH69|Q9YH69_CHICK
Dermo protein
Search

TWIST2

0.96	Twist family bHLH transcription factor 2

0.55	GO:0045668	negative regulation of osteoblast differentiation
0.47	GO:2000793	cell proliferation involved in heart valve development
0.47	GO:0140051	positive regulation of endocardial cushion to mesenchymal transition
0.47	GO:2000800	regulation of endocardial cushion to mesenchymal transition involved in heart valve formation
0.46	GO:0033128	negative regulation of histone phosphorylation
0.46	GO:2000276	negative regulation of oxidative phosphorylation uncoupler activity
0.46	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway
0.46	GO:0003180	aortic valve morphogenesis
0.46	GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis
0.46	GO:0032000	positive regulation of fatty acid beta-oxidation

0.68	GO:0046983	protein dimerization activity
0.45	GO:0043425	bHLH transcription factor binding
0.45	GO:0070888	E-box binding
0.43	GO:0019904	protein domain specific binding
0.41	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.41	GO:0042802	identical protein binding
0.36	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.36	GO:0003682	chromatin binding

0.46	GO:0005730	nucleolus
0.37	GO:0005737	cytoplasm
0.35	GO:0005667	transcription factor complex
0.35	GO:0005654	nucleoplasm

sp|Q9YH85|TECTA_CHICK
Alpha-tectorin
Search

TECTA

0.80	LOW QUALITY PROTEIN: alpha-tectorin

0.82	GO:0007605	sensory perception of sound
0.78	GO:0007160	cell-matrix adhesion
0.52	GO:0035889	otolith tethering
0.37	GO:0006501	C-terminal protein lipidation
0.33	GO:0008610	lipid biosynthetic process
0.32	GO:0055114	oxidation-reduction process

0.82	GO:0005201	extracellular matrix structural constituent
0.34	GO:0005515	protein binding
0.32	GO:0005506	iron ion binding
0.32	GO:0016491	oxidoreductase activity
0.31	GO:0005509	calcium ion binding

0.76	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0070062	extracellular exosome
0.38	GO:0031225	anchored component of membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.32

GO:0016491

sp|Q9YH98|EYA4_CHICK
Eyes absent homolog 4 (Fragment)
Search

EYA4

0.44	Eyes absent homolog

0.80	GO:0007605	sensory perception of sound
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.69	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:0016576	histone dephosphorylation
0.47	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.46	GO:0045739	positive regulation of DNA repair
0.45	GO:0030154	cell differentiation

0.74	GO:0004725	protein tyrosine phosphatase activity
0.54	GO:0046872	metal ion binding
0.36	GO:0008134	transcription factor binding
0.33	GO:0008289	lipid binding
0.33	GO:0003735	structural constituent of ribosome

0.39	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex
0.33	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle

0.74

GO:0004725

sp|Q9YH99|EYA3_CHICK
Eyes absent homolog 3 (Fragment)
Search

EYA3

0.42	Eyes absent homolog

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.69	GO:0007275	multicellular organism development
0.57	GO:0016576	histone dephosphorylation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0045739	positive regulation of DNA repair
0.53	GO:0010212	response to ionizing radiation
0.49	GO:0006302	double-strand break repair
0.47	GO:1901099	negative regulation of signal transduction in absence of ligand

0.74	GO:0004725	protein tyrosine phosphatase activity
0.53	GO:0046872	metal ion binding
0.37	GO:0004992	platelet activating factor receptor activity
0.36	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.36	GO:0003682	chromatin binding
0.36	GO:0005515	protein binding

0.74	GO:0005667	transcription factor complex
0.50	GO:0005813	centrosome
0.47	GO:0005654	nucleoplasm
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.74

GO:0004725

sp|Q9YHA0|EYA1_CHICK
Eyes absent homolog 1 (Fragment)
Search

0.44	Eyes absent homolog

0.83	GO:0042471	ear morphogenesis
0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0016576	histone dephosphorylation
0.55	GO:0071599	otic vesicle development
0.55	GO:0072513	positive regulation of secondary heart field cardioblast proliferation
0.55	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.54	GO:0007501	mesodermal cell fate specification

0.75	GO:0004725	protein tyrosine phosphatase activity
0.54	GO:0046872	metal ion binding
0.42	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.51	GO:0016604	nuclear body
0.47	GO:0032993	protein-DNA complex
0.42	GO:0043234	protein complex
0.38	GO:0005737	cytoplasm

0.75

GO:0004725

sp|Q9YHT1|SDHA_CHICK
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Search

SDHA

0.68	Succinate dehydrogenase [ubiquinone] flavoprotein subunit A, mitochondrial

0.70	GO:0006099	tricarboxylic acid cycle
0.60	GO:0022900	electron transport chain
0.52	GO:0006105	succinate metabolic process
0.47	GO:0007399	nervous system development
0.44	GO:0009061	anaerobic respiration
0.40	GO:0006119	oxidative phosphorylation
0.37	GO:0006106	fumarate metabolic process
0.34	GO:0007034	vacuolar transport

0.78	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.65	GO:0050660	flavin adenine dinucleotide binding
0.40	GO:0009055	electron transfer activity
0.37	GO:0004333	fumarate hydratase activity
0.35	GO:0005515	protein binding

0.56	GO:0031966	mitochondrial membrane
0.56	GO:0019866	organelle inner membrane
0.49	GO:0045282	plasma membrane succinate dehydrogenase complex
0.48	GO:0043209	myelin sheath
0.48	GO:0045257	succinate dehydrogenase complex (ubiquinone)
0.48	GO:0045283	fumarate reductase complex
0.47	GO:0005730	nucleolus
0.44	GO:0098798	mitochondrial protein complex
0.36	GO:0045239	tricarboxylic acid cycle enzyme complex
0.30	GO:0031224	intrinsic component of membrane

0.78	EC:1.3.5.1	GO:0008177
0.78	KEGG:R02164	GO:0008177

sp|Q9YHT2|SDHB_CHICK
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Search

SDHB

0.68	Succinate dehydrogenase complex iron sulfur subunit B

0.69	GO:0006099	tricarboxylic acid cycle
0.59	GO:0022900	electron transport chain
0.37	GO:0006105	succinate metabolic process
0.34	GO:0018101	protein citrullination

0.77	GO:0051538	3 iron, 4 sulfur cluster binding
0.77	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.69	GO:0051537	2 iron, 2 sulfur cluster binding
0.65	GO:0051539	4 iron, 4 sulfur cluster binding
0.60	GO:0009055	electron transfer activity
0.53	GO:0046872	metal ion binding
0.44	GO:0048039	ubiquinone binding
0.34	GO:0004668	protein-arginine deiminase activity
0.34	GO:0005515	protein binding

0.60	GO:0031966	mitochondrial membrane
0.60	GO:0019866	organelle inner membrane
0.54	GO:0045257	succinate dehydrogenase complex (ubiquinone)
0.54	GO:0045283	fumarate reductase complex
0.48	GO:0098798	mitochondrial protein complex
0.46	GO:0005654	nucleoplasm
0.40	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome

0.77	EC:1.3.5.1	GO:0008177
0.77	KEGG:R02164	GO:0008177

tr|Q9YHW6|Q9YHW6_CHICK
Ets domain protein
Search

ETV1

0.96	Ets transcription factor

0.85	GO:0048935	peripheral nervous system neuron development
0.75	GO:0006366	transcription by RNA polymerase II
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0007638	mechanosensory behavior
0.49	GO:0007517	muscle organ development
0.49	GO:0007411	axon guidance
0.48	GO:1902680	positive regulation of RNA biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.61

GO:0005634

nucleus

sp|Q9YHY9|OTC_CHICK
Ornithine carbamoyltransferase, mitochondrial
Search

OTC

0.45	Ornithine carbamoyltransferase

0.65	GO:0019240	citrulline biosynthetic process
0.65	GO:0000050	urea cycle
0.64	GO:0097272	ammonia homeostasis
0.62	GO:0006593	ornithine catabolic process
0.50	GO:0042450	arginine biosynthetic process via ornithine
0.43	GO:0070781	response to biotin
0.42	GO:0007494	midgut development
0.41	GO:0070207	protein homotrimerization
0.41	GO:0010043	response to zinc ion
0.41	GO:0001889	liver development

0.75	GO:0016743	carboxyl- or carbamoyltransferase activity
0.75	GO:0016597	amino acid binding
0.40	GO:0042301	phosphate ion binding
0.39	GO:0005543	phospholipid binding

0.49	GO:0005739	mitochondrion
0.48	GO:0019866	organelle inner membrane
0.40	GO:0031974	membrane-enclosed lumen
0.37	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.75

EC:2.1.3

GO:0016743

tr|Q9YI38|Q9YI38_CHICK
Mox-1 related protein
Search

MEOX1

0.97	Homeobox protein MOX-1

0.68	GO:0001757	somite specification
0.62	GO:0061056	sclerotome development
0.59	GO:0006366	transcription by RNA polymerase II
0.59	GO:0045944	positive regulation of transcription by RNA polymerase II
0.53	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis
0.52	GO:0070997	neuron death
0.52	GO:0061061	muscle structure development
0.51	GO:0060021	palate development
0.50	GO:0060173	limb development
0.50	GO:0014706	striated muscle tissue development

0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.60	GO:0001012	RNA polymerase II regulatory region DNA binding
0.59	GO:0071837	HMG box domain binding
0.57	GO:0001047	core promoter binding
0.57	GO:0003690	double-stranded DNA binding
0.55	GO:0003682	chromatin binding
0.53	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.51	GO:0035326	enhancer binding

0.60	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part

tr|Q9YI58|Q9YI58_CHICK
Glutamate decarboxylase 1
Search

GAD1

0.53	Glutamate decarboxylase

0.57	GO:0019752	carboxylic acid metabolic process
0.57	GO:0035641	locomotory exploration behavior
0.55	GO:0035176	social behavior
0.46	GO:0042136	neurotransmitter biosynthetic process
0.39	GO:0016053	organic acid biosynthetic process
0.38	GO:0042493	response to drug
0.37	GO:1901566	organonitrogen compound biosynthetic process
0.36	GO:0018352	protein-pyridoxal-5-phosphate linkage
0.35	GO:0099643	signal release from synapse
0.35	GO:0099531	presynaptic process involved in chemical synaptic transmission

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.42	GO:0016595	glutamate binding
0.40	GO:0047485	protein N-terminus binding
0.38	GO:0046982	protein heterodimerization activity

0.56	GO:0060077	inhibitory synapse
0.54	GO:0043679	axon terminus
0.54	GO:0048786	presynaptic active zone
0.52	GO:0030424	axon
0.50	GO:0005938	cell cortex
0.44	GO:0005739	mitochondrion
0.36	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle
0.35	GO:0030665	clathrin-coated vesicle membrane
0.32	GO:0005886	plasma membrane

0.68

EC:4.1.1

GO:0016831

sp|Q9YIB9|HIF1A_CHICK
Hypoxia-inducible factor 1-alpha
Search

HIF1A

0.89	Hypoxia inducible factor 1 alpha subunit

0.59	GO:0061419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.59	GO:0051541	elastin metabolic process
0.59	GO:0060574	intestinal epithelial cell maturation
0.59	GO:0021502	neural fold elevation formation
0.59	GO:0002248	connective tissue replacement involved in inflammatory response wound healing
0.58	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway
0.58	GO:0032364	oxygen homeostasis
0.58	GO:0019896	axonal transport of mitochondrion
0.58	GO:0001922	B-1 B cell homeostasis
0.58	GO:0010573	vascular endothelial growth factor production

0.65	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0035035	histone acetyltransferase binding
0.56	GO:0070888	E-box binding
0.56	GO:0051879	Hsp90 protein binding
0.55	GO:0042826	histone deacetylase binding
0.54	GO:0002039	p53 binding
0.54	GO:0035257	nuclear hormone receptor binding
0.52	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding

0.61	GO:0005634	nucleus
0.56	GO:1904115	axon cytoplasm
0.52	GO:0031514	motile cilium
0.50	GO:0005667	transcription factor complex
0.49	GO:0070013	intracellular organelle lumen
0.48	GO:0005829	cytosol
0.44	GO:0044446	intracellular organelle part

tr|R4GF38|R4GF38_CHICK
Uncharacterized protein
Search

STARD10

0.96	START domain-containing protein 10

0.57	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway
0.57	GO:0032782	bile acid secretion
0.35	GO:0006869	lipid transport
0.35	GO:0006656	phosphatidylcholine biosynthetic process
0.33	GO:0007165	signal transduction

0.72	GO:0008289	lipid binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0005515	protein binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0046581	intercellular canaliculus
0.57	GO:0005902	microvillus
0.49	GO:0005829	cytosol
0.34	GO:0031514	motile cilium
0.30	GO:0016020	membrane

tr|R4GF39|R4GF39_CHICK
Uncharacterized protein
Search

0.97	TraB domain containing 2B

0.80	GO:0030178	negative regulation of Wnt signaling pathway
0.76	GO:1904808	positive regulation of protein oxidation
0.71	GO:0032461	positive regulation of protein oligomerization
0.59	GO:0006508	proteolysis

0.83	GO:0017147	Wnt-protein binding
0.68	GO:0004222	metalloendopeptidase activity

0.74	GO:0031301	integral component of organelle membrane
0.65	GO:0005887	integral component of plasma membrane
0.41	GO:0070062	extracellular exosome

0.68

GO:0004222

tr|R4GF52|R4GF52_CHICK
Uncharacterized protein
Search

OMD

0.97	Osteomodulin

0.77	GO:0030500	regulation of bone mineralization
0.50	GO:0007409	axonogenesis
0.41	GO:0061303	cornea development in camera-type eye
0.39	GO:0007155	cell adhesion
0.37	GO:0042340	keratan sulfate catabolic process
0.37	GO:0007569	cell aging
0.37	GO:0018146	keratan sulfate biosynthetic process
0.35	GO:0045087	innate immune response
0.34	GO:0046426	negative regulation of JAK-STAT cascade
0.34	GO:0007165	signal transduction

0.51	GO:0005518	collagen binding
0.46	GO:0005509	calcium ion binding
0.45	GO:0005201	extracellular matrix structural constituent
0.34	GO:0008201	heparin binding
0.34	GO:0004860	protein kinase inhibitor activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0031012	extracellular matrix
0.48	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.37	GO:0043202	lysosomal lumen
0.36	GO:0005796	Golgi lumen
0.30	GO:0031224	intrinsic component of membrane

tr|R4GF53|R4GF53_CHICK
Uncharacterized protein
Search

GRPR

0.97	Gastrin releasing peptide receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.58	GO:0036343	psychomotor behavior
0.56	GO:0035176	social behavior
0.51	GO:0042127	regulation of cell proliferation
0.48	GO:0043207	response to external biotic stimulus
0.34	GO:0007611	learning or memory
0.34	GO:0008283	cell proliferation

0.79	GO:0008528	G-protein coupled peptide receptor activity
0.35	GO:0042923	neuropeptide binding
0.33	GO:0005515	protein binding

0.47	GO:0005887	integral component of plasma membrane
0.38	GO:0005829	cytosol

tr|R4GF57|R4GF57_CHICK
Keratin
Search

0.73	Claw keratin

0.70

GO:0007010

cytoskeleton organization

0.76

GO:0005200

structural constituent of cytoskeleton

0.78	GO:0005882	intermediate filament
0.30	GO:0031224	intrinsic component of membrane

tr|R4GF58|R4GF58_CHICK
Uncharacterized protein
Search

OPRL1

0.97	Nociceptin receptor

0.80	GO:0038003	opioid receptor signaling pathway
0.55	GO:0019233	sensory perception of pain
0.54	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.52	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.44	GO:0007218	neuropeptide signaling pathway
0.43	GO:0007268	chemical synaptic transmission
0.40	GO:0060454	positive regulation of gastric acid secretion
0.39	GO:1904058	positive regulation of sensory perception of pain
0.39	GO:0044849	estrous cycle
0.39	GO:0106072	negative regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway

0.84	GO:0001626	nociceptin receptor activity
0.46	GO:0042923	neuropeptide binding
0.38	GO:0008022	protein C-terminus binding

0.46	GO:0005887	integral component of plasma membrane
0.43	GO:0043005	neuron projection
0.37	GO:0031410	cytoplasmic vesicle

tr|R4GF61|R4GF61_CHICK
Uncharacterized protein
Search

CTXN3

0.95	Cortexin 3

0.30

GO:0044425

membrane part

tr|R4GF62|R4GF62_CHICK
28S ribosomal protein S6, mitochondrial
Search

MRPS6

0.97	Mitochondrial ribosomal protein S6

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.34	GO:0043624	cellular protein complex disassembly
0.32	GO:0055085	transmembrane transport

0.66	GO:0019843	rRNA binding
0.64	GO:0003735	structural constituent of ribosome
0.33	GO:0005515	protein binding
0.33	GO:0022857	transmembrane transporter activity

0.61	GO:0005840	ribosome
0.53	GO:0005759	mitochondrial matrix
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

tr|R4GF68|R4GF68_CHICK
Uncharacterized protein
Search

0.12	SZT2, KICSTOR complex subunit

0.85	GO:0021540	corpus callosum morphogenesis
0.84	GO:1901668	regulation of superoxide dismutase activity
0.83	GO:0061462	protein localization to lysosome
0.83	GO:1904262	negative regulation of TORC1 signaling
0.81	GO:0034198	cellular response to amino acid starvation
0.80	GO:0042149	cellular response to glucose starvation
0.78	GO:0043473	pigmentation
0.73	GO:0009791	post-embryonic development

0.36

GO:0005515

protein binding

0.85	GO:0140007	KICSTOR complex
0.84	GO:1990130	GATOR1 complex
0.82	GO:0061700	GATOR2 complex
0.77	GO:0005765	lysosomal membrane
0.76	GO:0005777	peroxisome
0.43	GO:0070062	extracellular exosome

tr|R4GF71|R4GF71_CHICK
Uncharacterized protein
Search

0.96	Thymosin beta 4 X-linked

0.75	GO:0007015	actin filament organization
0.47	GO:1905271	regulation of proton-transporting ATP synthase activity, rotational mechanism
0.47	GO:0042989	sequestering of actin monomers
0.46	GO:0007253	cytoplasmic sequestering of NF-kappaB
0.46	GO:2000483	negative regulation of interleukin-8 secretion
0.46	GO:2001171	positive regulation of ATP biosynthetic process
0.46	GO:1901223	negative regulation of NIK/NF-kappaB signaling
0.46	GO:2001028	positive regulation of endothelial cell chemotaxis
0.45	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
0.45	GO:0043536	positive regulation of blood vessel endothelial cell migration

0.85	GO:0003785	actin monomer binding
0.41	GO:0019899	enzyme binding
0.35	GO:0003727	single-stranded RNA binding
0.34	GO:0004888	transmembrane signaling receptor activity

0.43	GO:0005856	cytoskeleton
0.41	GO:0005829	cytosol
0.41	GO:0005576	extracellular region
0.40	GO:0005634	nucleus
0.35	GO:0031093	platelet alpha granule lumen
0.30	GO:0016020	membrane

tr|R4GF75|R4GF75_CHICK
Uncharacterized protein
Search

MALT1

0.92	MALT paracaspase 2

0.78	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.70	GO:0001923	B-1 B cell differentiation
0.68	GO:0002726	positive regulation of T cell cytokine production
0.67	GO:0007250	activation of NF-kappaB-inducing kinase activity
0.67	GO:0032743	positive regulation of interleukin-2 production
0.67	GO:0042098	T cell proliferation
0.66	GO:0050856	regulation of T cell receptor signaling pathway
0.66	GO:0050852	T cell receptor signaling pathway
0.63	GO:0009620	response to fungus
0.63	GO:0002237	response to molecule of bacterial origin

0.75	GO:0004197	cysteine-type endopeptidase activity
0.65	GO:0002020	protease binding
0.65	GO:0043621	protein self-association
0.63	GO:0019209	kinase activator activity
0.58	GO:0042802	identical protein binding
0.58	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0004871	signal transducer activity

0.70	GO:0032449	CBM complex
0.64	GO:0001650	fibrillar center
0.54	GO:0005829	cytosol

0.75	EC:3.4.22	GO:0004197
0.58	KEGG:R03876	GO:0004842

tr|R4GF78|R4GF78_CHICK
Uncharacterized protein
Search

0.71	Ig heavy chain V-III region NIE

tr|R4GF80|R4GF80_CHICK
Uncharacterized protein
Search

GHSR

0.86	Growth hormone secretagogue receptor a

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.60	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process
0.60	GO:0032100	positive regulation of appetite
0.59	GO:0045409	negative regulation of interleukin-6 biosynthetic process
0.59	GO:0030252	growth hormone secretion
0.58	GO:0032691	negative regulation of interleukin-1 beta production
0.58	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway
0.58	GO:0032094	response to food
0.57	GO:0008343	adult feeding behavior
0.57	GO:0040018	positive regulation of multicellular organism growth

0.86	GO:0016520	growth hormone-releasing hormone receptor activity
0.62	GO:0001616	growth hormone secretagogue receptor activity
0.42	GO:0017046	peptide hormone binding
0.35	GO:0005131	growth hormone receptor binding

0.54	GO:0098857	membrane microdomain
0.52	GO:0043005	neuron projection
0.52	GO:0009986	cell surface
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|R4GF89|R4GF89_CHICK
Uncharacterized protein
Search

SFN

0.96	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta

0.56	GO:0010482	regulation of epidermal cell division
0.55	GO:0001836	release of cytochrome c from mitochondria
0.55	GO:0010839	negative regulation of keratinocyte proliferation
0.55	GO:0045606	positive regulation of epidermal cell differentiation
0.55	GO:0003334	keratinocyte development
0.55	GO:0061436	establishment of skin barrier
0.54	GO:0031424	keratinization
0.54	GO:0046827	positive regulation of protein export from nucleus
0.53	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.53	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

0.77	GO:0019904	protein domain specific binding
0.54	GO:0042802	identical protein binding
0.52	GO:0051219	phosphoprotein binding
0.52	GO:0045296	cadherin binding
0.50	GO:0047485	protein N-terminus binding
0.50	GO:0019901	protein kinase binding
0.38	GO:0071889	14-3-3 protein binding
0.38	GO:0044325	ion channel binding
0.38	GO:0008022	protein C-terminus binding
0.37	GO:0004497	monooxygenase activity

0.47	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.41	GO:0043234	protein complex
0.38	GO:0031982	vesicle
0.37	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space
0.35	GO:0005925	focal adhesion
0.35	GO:0031090	organelle membrane
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005739	mitochondrion

0.35

EC:2.4.1.130

GO:0004584

tr|R4GF92|R4GF92_CHICK
Uncharacterized protein
Search

PCBP4

0.96	Poly(rC) binding protein 4

0.56	GO:0043488	regulation of mRNA stability
0.39	GO:1902163	negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.37	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.35	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

0.59	GO:0003723	RNA binding
0.34	GO:0003677	DNA binding

0.49	GO:0005829	cytosol
0.35	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

tr|R4GFA9|R4GFA9_CHICK
Uncharacterized protein
Search

MED18

0.96	Mediator of RNA polymerase II transcription subunit 18

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.37	GO:0016567	protein ubiquitination
0.32	GO:2001045	negative regulation of integrin-mediated signaling pathway
0.32	GO:0061386	closure of optic fissure
0.32	GO:0048484	enteric nervous system development
0.32	GO:0001755	neural crest cell migration
0.32	GO:0001843	neural tube closure
0.32	GO:0007266	Rho protein signal transduction
0.32	GO:0032515	negative regulation of phosphoprotein phosphatase activity

0.79	GO:0001104	RNA polymerase II transcription cofactor activity
0.38	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0005515	protein binding
0.32	GO:0072542	protein phosphatase activator activity
0.32	GO:0004864	protein phosphatase inhibitor activity

0.77	GO:0016592	mediator complex
0.48	GO:0070847	core mediator complex
0.38	GO:0000151	ubiquitin ligase complex
0.32	GO:0030027	lamellipodium

tr|R4GFB3|R4GFB3_CHICK
Phosphoinositide phospholipase C
Search

PLCB4

0.53	Phosphoinositide phospholipase C

0.71	GO:0016042	lipid catabolic process
0.62	GO:0035556	intracellular signal transduction

0.80	GO:0004435	phosphatidylinositol phospholipase C activity
0.68	GO:0005509	calcium ion binding
0.63	GO:0004871	signal transducer activity
0.36	GO:0005515	protein binding

0.56	GO:0005790	smooth endoplasmic reticulum
0.54	GO:0014069	postsynaptic density
0.53	GO:0030425	dendrite
0.44	GO:0005634	nucleus

0.80	EC:3.1.4.11	GO:0004435
0.80	KEGG:R03435	GO:0004435

tr|R4GFB4|R4GFB4_CHICK
Uncharacterized protein
Search

0.72	Death-associated protein kinase 2

0.63	GO:0006468	protein phosphorylation
0.50	GO:0006915	apoptotic process
0.48	GO:0043519	regulation of myosin II filament organization
0.48	GO:0071346	cellular response to interferon-gamma
0.47	GO:2000249	regulation of actin cytoskeleton reorganization
0.47	GO:0090109	regulation of cell-substrate junction assembly
0.47	GO:1903391	regulation of adherens junction organization
0.46	GO:0001952	regulation of cell-matrix adhesion
0.46	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.45	GO:0043065	positive regulation of apoptotic process

0.66	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.48	GO:0043522	leucine zipper domain binding
0.44	GO:0017048	Rho GTPase binding
0.44	GO:0042802	identical protein binding
0.41	GO:0046983	protein dimerization activity
0.37	GO:0008022	protein C-terminus binding

0.46	GO:0016605	PML body
0.38	GO:0015629	actin cytoskeleton
0.37	GO:0098857	membrane microdomain
0.36	GO:0099513	polymeric cytoskeletal fiber
0.35	GO:0005737	cytoplasm
0.35	GO:0000775	chromosome, centromeric region
0.33	GO:0005815	microtubule organizing center
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.66

GO:0004674

tr|R4GFB9|R4GFB9_CHICK
Uncharacterized protein
Search

RRP36

0.87	Ribosomal RNA processing protein 36

0.82	GO:0000469	cleavage involved in rRNA processing
0.47	GO:0042274	ribosomal small subunit biogenesis
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.43	GO:0003682	chromatin binding
0.37	GO:0046983	protein dimerization activity
0.33	GO:0003723	RNA binding

0.72	GO:0005730	nucleolus
0.44	GO:0030686	90S preribosome
0.43	GO:0000790	nuclear chromatin
0.42	GO:0005654	nucleoplasm
0.36	GO:0005737	cytoplasm

tr|R4GFC6|R4GFC6_CHICK
Uncharacterized protein
Search

TNFSF11

0.97	Tumor necrosis factor ligand superfamily member 11

0.74	GO:0006955	immune response
0.68	GO:0051466	positive regulation of corticotropin-releasing hormone secretion
0.67	GO:0071812	positive regulation of fever generation by positive regulation of prostaglandin secretion
0.67	GO:0071848	positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling
0.67	GO:0002158	osteoclast proliferation
0.66	GO:2001206	positive regulation of osteoclast development
0.66	GO:0034112	positive regulation of homotypic cell-cell adhesion
0.66	GO:0038001	paracrine signaling
0.65	GO:0045780	positive regulation of bone resorption
0.64	GO:0045453	bone resorption

0.83	GO:0005164	tumor necrosis factor receptor binding
0.59	GO:0005125	cytokine activity

0.39	GO:0005622	intracellular
0.37	GO:0005615	extracellular space
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|R4GFC7|R4GFC7_CHICK
Uncharacterized protein
Search

SLA2

0.94	Src like adaptor

0.73	GO:0009967	positive regulation of signal transduction
0.54	GO:0050849	negative regulation of calcium-mediated signaling
0.50	GO:0042110	T cell activation
0.50	GO:0038083	peptidyl-tyrosine autophosphorylation
0.49	GO:0000122	negative regulation of transcription by RNA polymerase II
0.48	GO:0043551	regulation of phosphatidylinositol 3-kinase activity
0.47	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.47	GO:0045087	innate immune response
0.47	GO:0016477	cell migration
0.46	GO:0042127	regulation of cell proliferation

0.83	GO:0005070	SH3/SH2 adaptor activity
0.52	GO:0047485	protein N-terminus binding
0.48	GO:0035014	phosphatidylinositol 3-kinase regulator activity
0.48	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.45	GO:0005102	receptor binding
0.34	GO:0001784	phosphotyrosine residue binding
0.32	GO:0016303	1-phosphatidylinositol-3-kinase activity

0.51	GO:0019898	extrinsic component of membrane
0.49	GO:0005770	late endosome
0.46	GO:0005794	Golgi apparatus
0.46	GO:0009898	cytoplasmic side of plasma membrane
0.46	GO:0005654	nucleoplasm
0.43	GO:0061695	transferase complex, transferring phosphorus-containing groups
0.36	GO:0000444	MIS12/MIND type complex
0.34	GO:0010008	endosome membrane
0.32	GO:0005829	cytosol

0.48	EC:2.7.10.2	GO:0004715
0.32	KEGG:R03362	GO:0016303

tr|R4GFC8|R4GFC8_CHICK
Uncharacterized protein
Search

FRRS1L

0.97	Ferric chelate reductase 1 like

0.59	GO:1900449	regulation of glutamate receptor signaling pathway
0.34	GO:0097502	mannosylation
0.34	GO:0006486	protein glycosylation
0.32	GO:0055114	oxidation-reduction process

0.35	GO:0000033	alpha-1,3-mannosyltransferase activity
0.34	GO:0008092	cytoskeletal protein binding

0.38	GO:0045202	synapse
0.38	GO:0030054	cell junction
0.35	GO:0005856	cytoskeleton
0.35	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.35

GO:0000033

tr|R4GFD9|R4GFD9_CHICK
Uncharacterized protein
Search

tr|R4GFE0|R4GFE0_CHICK
Uncharacterized protein
Search

SUB1

0.94	activated RNA polymerase II transcriptional coactivator p15

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.42	GO:0051260	protein homooligomerization
0.41	GO:0031334	positive regulation of protein complex assembly
0.41	GO:0051254	positive regulation of RNA metabolic process
0.41	GO:0060395	SMAD protein signal transduction
0.41	GO:0010557	positive regulation of macromolecule biosynthetic process
0.41	GO:0031328	positive regulation of cellular biosynthetic process
0.40	GO:0032392	DNA geometric change

0.77	GO:0003713	transcription coactivator activity
0.54	GO:0003677	DNA binding
0.44	GO:0033613	activating transcription factor binding
0.42	GO:0042802	identical protein binding
0.41	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.40	GO:0003678	DNA helicase activity
0.34	GO:0003723	RNA binding

0.44	GO:0005667	transcription factor complex
0.42	GO:0005730	nucleolus
0.37	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

tr|R4GFE2|R4GFE2_CHICK
Uncharacterized protein
Search

TMEM204

0.97	Transmembrane protein 204

0.63	GO:0051145	smooth muscle cell differentiation
0.63	GO:0001945	lymph vessel development
0.63	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway

0.33

GO:0005515

protein binding

0.45	GO:0005886	plasma membrane
0.40	GO:0005912	adherens junction
0.30	GO:0044425	membrane part

tr|R4GFE8|R4GFE8_CHICK
Uncharacterized protein
Search

0.62	GO:0035556	intracellular signal transduction
0.55	GO:0042461	photoreceptor cell development
0.53	GO:0035082	axoneme assembly
0.53	GO:0060041	retina development in camera-type eye
0.46	GO:0045494	photoreceptor cell maintenance
0.44	GO:0007601	visual perception
0.43	GO:1902857	positive regulation of non-motile cilium assembly
0.43	GO:0001754	eye photoreceptor cell differentiation
0.43	GO:0048593	camera-type eye morphogenesis
0.41	GO:0071482	cellular response to light stimulus

0.42

GO:0008017

microtubule binding

0.52	GO:0005930	axoneme
0.47	GO:0001750	photoreceptor outer segment
0.44	GO:0032391	photoreceptor connecting cilium
0.43	GO:0001917	photoreceptor inner segment
0.43	GO:0097542	ciliary tip
0.41	GO:0005875	microtubule associated complex
0.36	GO:0005874	microtubule
0.34	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

tr|R4GFF0|R4GFF0_CHICK
Galactose-1-phosphate uridylyltransferase
Search

GALT

0.59	Galactose-1-phosphate uridylyltransferase

0.81	GO:0033499	galactose catabolic process via UDP-galactose
0.50	GO:0006011	UDP-glucose metabolic process
0.41	GO:0009227	nucleotide-sugar catabolic process
0.38	GO:0019221	cytokine-mediated signaling pathway
0.38	GO:0061623	glycolytic process from galactose
0.35	GO:0033501	galactose homeostasis
0.34	GO:0008344	adult locomotory behavior

0.81	GO:0008108	UDP-glucose:hexose-1-phosphate uridylyltransferase activity
0.63	GO:0008270	zinc ion binding
0.39	GO:0004896	cytokine receptor activity
0.34	GO:0005536	glucose binding
0.34	GO:0005534	galactose binding
0.33	GO:0005515	protein binding

0.47	GO:0005794	Golgi apparatus
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.81	EC:2.7.7.12	GO:0008108
0.81	KEGG:R00955	GO:0008108

tr|R4GFF1|R4GFF1_CHICK
Uncharacterized protein
Search

tr|R4GFF4|R4GFF4_CHICK
Uncharacterized protein
Search

SPTSSB

0.96	Small subunit of serine palmitoyltransferase B

0.60	GO:1904220	regulation of serine C-palmitoyltransferase activity
0.57	GO:0046513	ceramide biosynthetic process
0.54	GO:0007029	endoplasmic reticulum organization
0.36	GO:0000045	autophagosome assembly

0.62	GO:0016454	C-palmitoyltransferase activity
0.33	GO:0005515	protein binding

0.61	GO:0017059	serine C-palmitoyltransferase complex
0.30	GO:0031224	intrinsic component of membrane

0.62

EC:2.3.1

GO:0016454

tr|R4GFG6|R4GFG6_CHICK
Uncharacterized protein
Search

BG1

0.83	B-G antigen homologous

0.37	GO:1904622	negative regulation of actin-dependent ATPase activity
0.37	GO:1904616	regulation of actin binding
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.36	GO:0019903	protein phosphatase binding
0.35	GO:0003779	actin binding
0.32	GO:0046872	metal ion binding
0.31	GO:0003676	nucleic acid binding

0.37	GO:0031528	microvillus membrane
0.37	GO:0031526	brush border membrane
0.35	GO:0009986	cell surface
0.34	GO:0005887	integral component of plasma membrane
0.31	GO:0005622	intracellular

tr|R4GFG9|R4GFG9_CHICK
Uncharacterized protein
Search

0.17	t-SNARE domain-containing protein 1

0.65	GO:0006915	apoptotic process
0.57	GO:0016192	vesicle-mediated transport
0.50	GO:0090174	organelle membrane fusion
0.49	GO:0016050	vesicle organization
0.49	GO:0140056	organelle localization by membrane tethering
0.45	GO:0006886	intracellular protein transport

0.50	GO:0000149	SNARE binding
0.50	GO:0005484	SNAP receptor activity

0.53	GO:0005634	nucleus
0.50	GO:0031201	SNARE complex
0.44	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

tr|R4GFH1|R4GFH1_CHICK
Uncharacterized protein
Search

CAVIN2

0.97	Serum deprivation response

0.55	GO:0097320	plasma membrane tubulation
0.34	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0006363	termination of RNA polymerase I transcription

0.55	GO:0001786	phosphatidylserine binding
0.50	GO:0005080	protein kinase C binding

0.83	GO:0005901	caveola
0.49	GO:0015629	actin cytoskeleton
0.47	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol

tr|R4GFH4|R4GFH4_CHICK
Transcription factor 15
Search

TCF15

0.97	Basic helix-loop-helix transcription factor scleraxis

0.55	GO:0061053	somite development
0.55	GO:0007498	mesoderm development
0.55	GO:0003016	respiratory system process
0.55	GO:0060231	mesenchymal to epithelial transition
0.54	GO:0048705	skeletal system morphogenesis
0.54	GO:0045198	establishment of epithelial cell apical/basal polarity
0.54	GO:0050884	neuromuscular process controlling posture
0.54	GO:0060485	mesenchyme development
0.54	GO:0042755	eating behavior
0.54	GO:0036342	post-anal tail morphogenesis

0.68	GO:0046983	protein dimerization activity
0.54	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.50	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.43	GO:0043425	bHLH transcription factor binding
0.42	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.42	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

0.51	GO:0005667	transcription factor complex
0.45	GO:0005634	nucleus
0.41	GO:0044446	intracellular organelle part

tr|R4GFH6|R4GFH6_CHICK
Uncharacterized protein
Search

RNF146

0.89	E3 ubiquitin-protein ligase RNF146 isoform B

0.77	GO:0016055	Wnt signaling pathway
0.73	GO:0016567	protein ubiquitination
0.54	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.49	GO:0006511	ubiquitin-dependent protein catabolic process
0.35	GO:0016579	protein deubiquitination
0.35	GO:0051382	kinetochore assembly
0.34	GO:0000278	mitotic cell cycle

0.86	GO:0072572	poly-ADP-D-ribose binding
0.76	GO:0061630	ubiquitin protein ligase activity
0.63	GO:0008270	zinc ion binding
0.59	GO:0016874	ligase activity
0.35	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.47	GO:0005829	cytosol
0.43	GO:0005654	nucleoplasm
0.39	GO:0005886	plasma membrane

0.59

GO:0016874

tr|R4GFH7|R4GFH7_CHICK
Uncharacterized protein
Search

SPIC

0.97	Spi-C transcription factor

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0006366	transcription by RNA polymerase II
0.49	GO:1902680	positive regulation of RNA biosynthetic process
0.48	GO:0001824	blastocyst development
0.47	GO:0030154	cell differentiation
0.43	GO:0045646	regulation of erythrocyte differentiation
0.43	GO:0044027	hypermethylation of CpG island
0.43	GO:0045347	negative regulation of MHC class II biosynthetic process

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003690	double-stranded DNA binding
0.43	GO:0051525	NFAT protein binding
0.41	GO:0035326	enhancer binding
0.41	GO:0001085	RNA polymerase II transcription factor binding
0.41	GO:0001047	core promoter binding
0.34	GO:0003735	structural constituent of ribosome
0.32	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.39	GO:0000785	chromatin
0.38	GO:0070013	intracellular organelle lumen
0.34	GO:0005840	ribosome
0.33	GO:0005667	transcription factor complex

tr|R4GFI1|R4GFI1_CHICK
Uncharacterized protein
Search

0.68	Thrombospondin type-1 domain-containing protein 1

0.39	GO:0002244	hematopoietic progenitor cell differentiation
0.36	GO:0035335	peptidyl-tyrosine dephosphorylation

0.36	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032553	ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0009986	cell surface
0.48	GO:0005829	cytosol
0.34	GO:0071944	cell periphery
0.34	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

0.36

GO:0004725

tr|R4GFI5|R4GFI5_CHICK
Hexosyltransferase
Search

B3GNT4

0.54	Hexosyltransferase

0.74	GO:0006486	protein glycosylation
0.61	GO:0030311	poly-N-acetyllactosamine biosynthetic process
0.40	GO:1990830	cellular response to leukemia inhibitory factor
0.39	GO:0007411	axon guidance
0.38	GO:0007608	sensory perception of smell
0.32	GO:0006508	proteolysis

0.80	GO:0008378	galactosyltransferase activity
0.61	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity
0.32	GO:0017171	serine hydrolase activity
0.32	GO:0070011	peptidase activity, acting on L-amino acid peptides

0.74	GO:0000139	Golgi membrane
0.38	GO:0001650	fibrillar center
0.30	GO:0031224	intrinsic component of membrane

0.80

GO:0008378

tr|R4GFI6|R4GFI6_CHICK
Uncharacterized protein
Search

SLC46A2

0.97	Thymic stromal cotransporter

0.61	GO:0070233	negative regulation of T cell apoptotic process
0.60	GO:0043029	T cell homeostasis
0.60	GO:0048538	thymus development
0.59	GO:0045580	regulation of T cell differentiation
0.52	GO:0055085	transmembrane transport
0.33	GO:0006281	DNA repair

0.43

GO:0005215

transporter activity

0.54	GO:0009986	cell surface
0.35	GO:0070876	SOSS complex
0.35	GO:0016324	apical plasma membrane
0.30	GO:0016021	integral component of membrane

tr|R4GFI8|R4GFI8_CHICK
Uncharacterized protein
Search

0.90	Proproteinase E

0.61	GO:0006508	proteolysis
0.46	GO:0008203	cholesterol metabolic process
0.36	GO:0007586	digestion
0.35	GO:0050878	regulation of body fluid levels
0.34	GO:0030104	water homeostasis
0.34	GO:0050817	coagulation
0.34	GO:0043588	skin development
0.34	GO:0042060	wound healing
0.34	GO:0048871	multicellular organismal homeostasis
0.33	GO:1903506	regulation of nucleic acid-templated transcription

0.69	GO:0004252	serine-type endopeptidase activity
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005509	calcium ion binding

0.45	GO:0005615	extracellular space
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

tr|R4GFJ0|R4GFJ0_CHICK
Uncharacterized protein
Search

CPE

0.96	Carboxypeptidase E

0.62	GO:0030070	insulin processing
0.58	GO:0003214	cardiac left ventricle morphogenesis
0.52	GO:0016055	Wnt signaling pathway
0.50	GO:0072657	protein localization to membrane
0.36	GO:2000173	negative regulation of branching morphogenesis of a nerve
0.36	GO:0034230	enkephalin processing
0.35	GO:0007218	neuropeptide signaling pathway
0.34	GO:0043171	peptide catabolic process
0.33	GO:0036211	protein modification process
0.33	GO:0044267	cellular protein metabolic process

0.75	GO:0004181	metallocarboxypeptidase activity
0.61	GO:0008270	zinc ion binding
0.57	GO:0042043	neurexin family protein binding
0.54	GO:0050839	cell adhesion molecule binding
0.45	GO:0004185	serine-type carboxypeptidase activity
0.35	GO:0050897	cobalt ion binding
0.34	GO:0019904	protein domain specific binding

0.52	GO:0005615	extracellular space
0.51	GO:0005794	Golgi apparatus
0.47	GO:0043025	neuronal cell body
0.47	GO:0030141	secretory granule
0.46	GO:0097060	synaptic membrane
0.41	GO:0030658	transport vesicle membrane
0.37	GO:1903561	extracellular vesicle
0.35	GO:0030425	dendrite
0.35	GO:0045121	membrane raft
0.33	GO:0005634	nucleus

0.75

GO:0004181

tr|R4GFJ2|R4GFJ2_CHICK
Uncharacterized protein
Search

CPTP

0.96	Glycolipid transfer protein domain-containing protein 1

0.84	GO:0120009	intermembrane lipid transfer
0.69	GO:1902389	ceramide 1-phosphate transport
0.39	GO:0046836	glycolipid transport
0.36	GO:0006687	glycosphingolipid metabolic process

0.85	GO:0120013	intermembrane lipid transfer activity
0.69	GO:1902388	ceramide 1-phosphate transporter activity
0.69	GO:1902387	ceramide 1-phosphate binding

0.53	GO:0005829	cytosol
0.45	GO:0005640	nuclear outer membrane
0.42	GO:0010008	endosome membrane
0.41	GO:0005794	Golgi apparatus
0.37	GO:0005886	plasma membrane

tr|R4GFJ3|R4GFJ3_CHICK
Uncharacterized protein
Search

TRABD2A

0.97	TraB domain containing 2A

0.79	GO:0030178	negative regulation of Wnt signaling pathway
0.71	GO:1904808	positive regulation of protein oxidation
0.67	GO:0032461	positive regulation of protein oligomerization
0.59	GO:0006508	proteolysis

0.83	GO:0017147	Wnt-protein binding
0.68	GO:0004222	metalloendopeptidase activity

0.74	GO:0031301	integral component of organelle membrane
0.64	GO:0005887	integral component of plasma membrane
0.40	GO:0070062	extracellular exosome

0.68

GO:0004222

tr|R4GFJ9|R4GFJ9_CHICK
Adrenodoxin, mitochondrial
Search

FDX1

0.60	Adrenodoxin, mitochondrial

0.61	GO:0022900	electron transport chain
0.54	GO:1904321	response to forskolin
0.53	GO:0071320	cellular response to cAMP
0.52	GO:1901655	cellular response to ketone
0.52	GO:0008203	cholesterol metabolic process
0.50	GO:0035690	cellular response to drug
0.50	GO:0042446	hormone biosynthetic process
0.49	GO:0071396	cellular response to lipid
0.44	GO:1904087	negative regulation of epiboly involved in gastrulation with mouth forming second
0.40	GO:0006694	steroid biosynthetic process

0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.62	GO:0009055	electron transfer activity
0.35	GO:0046872	metal ion binding
0.35	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity
0.35	GO:0015039	NADPH-adrenodoxin reductase activity
0.34	GO:0008022	protein C-terminus binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0019899	enzyme binding

0.43	GO:0005739	mitochondrion
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.33	GO:0031090	organelle membrane
0.33	GO:0031975	envelope
0.30	GO:0044425	membrane part

0.35

EC:1.14.15.6

GO:0008386

tr|R4GFK3|R4GFK3_CHICK
Uncharacterized protein
Search

ERI2

0.84	ERI1 exoribonuclease family member 2

0.42	GO:0006259	DNA metabolic process
0.37	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.62	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.38	GO:0004527	exonuclease activity

0.30

GO:0031224

intrinsic component of membrane

tr|R4GFM3|R4GFM3_CHICK
Uncharacterized protein
Search

ERN1

0.87	Endoplasmic reticulum to nucleus signaling 2

0.70	GO:0006397	mRNA processing
0.69	GO:0090501	RNA phosphodiester bond hydrolysis
0.63	GO:0006468	protein phosphorylation
0.57	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.57	GO:0006987	activation of signaling protein activity involved in unfolded protein response
0.56	GO:0043507	positive regulation of JUN kinase activity
0.56	GO:0036498	IRE1-mediated unfolded protein response
0.56	GO:1901142	insulin metabolic process
0.56	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response
0.56	GO:0000187	activation of MAPK activity

0.69	GO:0004540	ribonuclease activity
0.64	GO:0004672	protein kinase activity
0.55	GO:0005161	platelet-derived growth factor receptor binding
0.55	GO:0030554	adenyl nucleotide binding
0.55	GO:0051879	Hsp90 protein binding
0.55	GO:0030544	Hsp70 protein binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0042803	protein homodimerization activity

0.59	GO:1990604	IRE1-TRAF2-ASK1 complex
0.57	GO:1990630	IRE1-RACK1-PP2A complex
0.57	GO:1990597	AIP1-IRE1 complex
0.52	GO:0005637	nuclear inner membrane
0.50	GO:0030176	integral component of endoplasmic reticulum membrane
0.43	GO:0005739	mitochondrion
0.36	GO:1990332	Ire1 complex

tr|R4GFM6|R4GFM6_CHICK
Uncharacterized protein
Search

0.72

Meleagrin

0.77	GO:0045087	innate immune response
0.50	GO:0050830	defense response to Gram-positive bacterium
0.49	GO:0050829	defense response to Gram-negative bacterium

0.65	GO:0005576	extracellular region
0.30	GO:0005623	cell

tr|R4GFN5|R4GFN5_CHICK
Uncharacterized protein
Search

0.96	N-methyl-D-aspartate receptor subunit

0.79	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.60	GO:0034220	ion transmembrane transport
0.56	GO:0060402	calcium ion transport into cytosol
0.55	GO:0019722	calcium-mediated signaling
0.55	GO:0050905	neuromuscular process
0.53	GO:0033058	directional locomotion
0.49	GO:0042177	negative regulation of protein catabolic process
0.48	GO:0051930	regulation of sensory perception of pain
0.48	GO:0009611	response to wounding

0.81	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.56	GO:0099604	ligand-gated calcium channel activity
0.52	GO:0022843	voltage-gated cation channel activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0016595	glutamate binding
0.34	GO:0042165	neurotransmitter binding

0.77	GO:0098794	postsynapse
0.76	GO:0097060	synaptic membrane
0.72	GO:0030054	cell junction
0.59	GO:0017146	NMDA selective glutamate receptor complex
0.49	GO:0032279	asymmetric synapse
0.46	GO:0097458	neuron part
0.38	GO:0043226	organelle
0.37	GO:0005622	intracellular

tr|R4GFN8|R4GFN8_CHICK
Uncharacterized protein
Search

ARMT1

0.49	Acidic residue methyltransferase 1

0.71	GO:2001020	regulation of response to DNA damage stimulus
0.66	GO:0008213	protein alkylation
0.61	GO:0032259	methylation
0.41	GO:0043401	steroid hormone mediated signaling pathway
0.40	GO:0006974	cellular response to DNA damage stimulus
0.39	GO:0016311	dephosphorylation
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:0010468	regulation of gene expression

0.70	GO:0051998	protein carboxyl O-methyltransferase activity
0.63	GO:0019899	enzyme binding
0.62	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.43	GO:0030284	estrogen receptor activity
0.42	GO:0005496	steroid binding
0.40	GO:0016791	phosphatase activity
0.38	GO:0043565	sequence-specific DNA binding
0.37	GO:0008270	zinc ion binding
0.37	GO:0003700	DNA binding transcription factor activity

0.37	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.40

EC:3.1.3 EC:3.1.3.41

GO:0016791

tr|R4GFP1|R4GFP1_CHICK
Kinesin-like protein
Search

tr|R4GFQ6|R4GFQ6_CHICK
Uncharacterized protein
Search

tr|R4GFR5|R4GFR5_CHICK
Uncharacterized protein
Search

PCSK4

0.89	LOW QUALITY PROTEIN: proprotein convertase subtilisin/kexin type 4

0.61	GO:0006508	proteolysis
0.52	GO:0048240	sperm capacitation
0.52	GO:0007340	acrosome reaction
0.52	GO:0007339	binding of sperm to zona pellucida
0.50	GO:0051604	protein maturation
0.46	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process
0.46	GO:0032902	nerve growth factor production
0.46	GO:0032911	negative regulation of transforming growth factor beta1 production
0.45	GO:0051216	cartilage development
0.45	GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process

0.69	GO:0004252	serine-type endopeptidase activity
0.46	GO:0048406	nerve growth factor binding
0.44	GO:0002020	protease binding
0.43	GO:0042277	peptide binding
0.42	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0008942	nitrite reductase [NAD(P)H] activity
0.32	GO:0046872	metal ion binding

0.52	GO:0002080	acrosomal membrane
0.43	GO:0030140	trans-Golgi network transport vesicle
0.43	GO:0045121	membrane raft
0.43	GO:0005802	trans-Golgi network
0.42	GO:0009986	cell surface
0.41	GO:0000139	Golgi membrane
0.41	GO:0005783	endoplasmic reticulum
0.34	GO:0010008	endosome membrane
0.33	GO:0043233	organelle lumen
0.33	GO:0005576	extracellular region

0.69	EC:3.4.21	GO:0004252
0.33	KEGG:R00787 KEGG:R00789	GO:0008942

tr|R4GFR8|R4GFR8_CHICK
Uncharacterized protein
Search

DNAJB2

0.88	DnaJ like protein subfamily B member 2

0.86	GO:1903644	regulation of chaperone-mediated protein folding
0.85	GO:0090084	negative regulation of inclusion body assembly
0.81	GO:0032091	negative regulation of protein binding
0.81	GO:0030308	negative regulation of cell growth
0.78	GO:0032781	positive regulation of ATPase activity
0.77	GO:0031396	regulation of protein ubiquitination
0.77	GO:0008285	negative regulation of cell proliferation
0.75	GO:0061077	chaperone-mediated protein folding
0.73	GO:0042026	protein refolding
0.52	GO:0090086	negative regulation of protein deubiquitination

0.84	GO:0030544	Hsp70 protein binding
0.78	GO:0001671	ATPase activator activity
0.74	GO:0051087	chaperone binding
0.68	GO:0051082	unfolded protein binding
0.49	GO:0031593	polyubiquitin modification-dependent protein binding
0.48	GO:0070628	proteasome binding
0.47	GO:0031625	ubiquitin protein ligase binding
0.39	GO:0005200	structural constituent of cytoskeleton
0.37	GO:0003924	GTPase activity
0.37	GO:0032550	purine ribonucleoside binding

0.76	GO:0031965	nuclear membrane
0.66	GO:0005829	cytosol
0.49	GO:0016234	inclusion body
0.46	GO:0031227	intrinsic component of endoplasmic reticulum membrane
0.45	GO:1905369	endopeptidase complex
0.40	GO:0043234	protein complex
0.38	GO:0005874	microtubule

tr|R4GFS5|R4GFS5_CHICK
Uncharacterized protein
Search

SNN

0.79

Stannin

0.34

GO:0009636

response to toxic substance

0.44	GO:0046872	metal ion binding
0.33	GO:0003677	DNA binding

0.41	GO:0005737	cytoplasm
0.39	GO:0031968	organelle outer membrane
0.35	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0044425	membrane part

tr|R4GFT0|R4GFT0_CHICK
Uncharacterized protein
Search

0.96	T-cell surface glycoprotein CD8 alpha chain

0.47	GO:0045065	cytotoxic T cell differentiation
0.44	GO:0002456	T cell mediated immunity
0.40	GO:0007166	cell surface receptor signaling pathway

0.61	GO:0044214	spanning component of plasma membrane
0.43	GO:0009897	external side of plasma membrane

tr|R4GFT1|R4GFT1_CHICK
Uncharacterized protein
Search

0.97	myeloma-overexpressed gene 2 protein homolog

0.79	GO:0034644	cellular response to UV
0.75	GO:0008284	positive regulation of cell proliferation
0.65	GO:2000435	negative regulation of protein neddylation
0.61	GO:0051220	cytoplasmic sequestering of protein
0.41	GO:0060326	cell chemotaxis
0.39	GO:0006955	immune response

0.42	GO:0005515	protein binding
0.42	GO:0031409	pigment binding
0.39	GO:0030545	receptor regulator activity
0.38	GO:0003723	RNA binding

0.76	GO:0008180	COP9 signalosome
0.71	GO:0000790	nuclear chromatin
0.66	GO:0005654	nucleoplasm
0.47	GO:0005737	cytoplasm
0.38	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|R4GFT3|R4GFT3_CHICK
Uncharacterized protein
Search

tr|R4GFT4|R4GFT4_CHICK
Uncharacterized protein
Search

tr|R4GFT6|R4GFT6_CHICK
Uncharacterized protein
Search

SUN2

0.82	SUN domain-containing protein 2

0.62	GO:0021817	nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration
0.61	GO:0090292	nuclear matrix anchoring at nuclear membrane
0.59	GO:0090286	cytoskeletal anchoring at nuclear membrane
0.59	GO:0051642	centrosome localization
0.58	GO:0006998	nuclear envelope organization
0.57	GO:0031022	nuclear migration along microfilament
0.51	GO:0030335	positive regulation of cell migration
0.46	GO:0070197	meiotic attachment of telomere to nuclear envelope
0.45	GO:0007129	synapsis
0.37	GO:0009612	response to mechanical stimulus

0.59	GO:0005521	lamin binding
0.51	GO:0043495	protein membrane anchor
0.48	GO:0042802	identical protein binding
0.34	GO:0008017	microtubule binding
0.34	GO:0004674	protein serine/threonine kinase activity

0.84	GO:0106094	nuclear membrane microtubule tethering complex
0.84	GO:0034992	microtubule organizing center attachment site
0.84	GO:0031229	intrinsic component of nuclear inner membrane
0.77	GO:0031301	integral component of organelle membrane
0.51	GO:0000784	nuclear chromosome, telomeric region
0.50	GO:0000794	condensed nuclear chromosome
0.46	GO:0002080	acrosomal membrane
0.35	GO:0010008	endosome membrane
0.35	GO:0005730	nucleolus
0.33	GO:0098589	membrane region

0.34

GO:0004674

tr|R4GFT9|R4GFT9_CHICK
Guanine nucleotide-binding protein subunit gamma
Search

GNG12

0.71	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:0021987	cerebral cortex development
0.37	GO:0032496	response to lipopolysaccharide
0.36	GO:0071377	cellular response to glucagon stimulus
0.36	GO:0007168	receptor guanylyl cyclase signaling pathway
0.36	GO:0001662	behavioral fear response
0.36	GO:0045761	regulation of adenylate cyclase activity
0.35	GO:0007626	locomotory behavior
0.34	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.34	GO:0006915	apoptotic process

0.64	GO:0004871	signal transducer activity
0.52	GO:0030165	PDZ domain binding
0.37	GO:0042301	phosphate ion binding
0.34	GO:0051015	actin filament binding
0.33	GO:0008017	microtubule binding
0.32	GO:0016787	hydrolase activity

0.81	GO:1905360	GTPase complex
0.80	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.66	GO:0098797	plasma membrane protein complex
0.38	GO:0070062	extracellular exosome
0.37	GO:0005884	actin filament
0.33	GO:0005874	microtubule

0.32

GO:0016787

tr|R4GFU3|R4GFU3_CHICK
Uncharacterized protein
Search

SEMA5A

0.90	Semaphorin-F

0.46	GO:0050919	negative chemotaxis
0.42	GO:1990256	signal clustering
0.42	GO:0048675	axon extension
0.42	GO:0050908	detection of light stimulus involved in visual perception
0.41	GO:0048842	positive regulation of axon extension involved in axon guidance
0.41	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.41	GO:0048843	negative regulation of axon extension involved in axon guidance
0.41	GO:0035413	positive regulation of catenin import into nucleus
0.41	GO:2001028	positive regulation of endothelial cell chemotaxis
0.40	GO:0097485	neuron projection guidance

0.47	GO:0038191	neuropilin binding
0.41	GO:0035373	chondroitin sulfate proteoglycan binding
0.41	GO:0045545	syndecan binding
0.41	GO:0030215	semaphorin receptor binding
0.40	GO:0043395	heparan sulfate proteoglycan binding
0.39	GO:0008046	axon guidance receptor activity

0.42	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|R4GFV0|R4GFV0_CHICK
Uncharacterized protein
Search

0.72	Mucosal addressin cell adhesion molecule 1

0.86	GO:2000403	positive regulation of lymphocyte migration
0.82	GO:0007160	cell-matrix adhesion
0.80	GO:0007229	integrin-mediated signaling pathway
0.75	GO:0098609	cell-cell adhesion

0.87

GO:0098640

integrin binding involved in cell-matrix adhesion

0.30

GO:0031224

intrinsic component of membrane

tr|R4GFV3|R4GFV3_CHICK
Uncharacterized protein
Search

MFAP5

0.94	Microfibrillar-associated protein 5

0.52	GO:0048513	animal organ development
0.47	GO:0002520	immune system development
0.47	GO:0048598	embryonic morphogenesis
0.46	GO:0097435	supramolecular fiber organization
0.45	GO:0009886	post-embryonic animal morphogenesis
0.40	GO:0001568	blood vessel development
0.35	GO:0030198	extracellular matrix organization
0.34	GO:0036344	platelet morphogenesis
0.33	GO:0006812	cation transport
0.33	GO:0048646	anatomical structure formation involved in morphogenesis

0.37	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
0.36	GO:0008270	zinc ion binding
0.35	GO:0005201	extracellular matrix structural constituent
0.35	GO:0097493	structural molecule activity conferring elasticity
0.35	GO:0005515	protein binding
0.34	GO:0016887	ATPase activity
0.33	GO:0051538	3 iron, 4 sulfur cluster binding
0.33	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0044877	macromolecular complex binding

0.86	GO:0001527	microfibril
0.48	GO:0005578	proteinaceous extracellular matrix
0.46	GO:0005615	extracellular space
0.32	GO:0031966	mitochondrial membrane
0.32	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.37	EC:3.5.4	GO:0016814
0.33	KEGG:R02164	GO:0008177

tr|R4GFW0|R4GFW0_CHICK
ELAV-like protein
Search

ELAVL2

0.85	ELAV-like protein 2

0.59	GO:1990830	cellular response to leukemia inhibitory factor
0.51	GO:0007275	multicellular organism development
0.51	GO:0008298	intracellular mRNA localization
0.48	GO:0051260	protein homooligomerization
0.48	GO:0000122	negative regulation of transcription by RNA polymerase II
0.47	GO:0000398	mRNA splicing, via spliceosome

0.59	GO:0003723	RNA binding
0.43	GO:0005515	protein binding

0.54	GO:0005938	cell cortex
0.46	GO:0030529	intracellular ribonucleoprotein complex
0.45	GO:0005654	nucleoplasm

tr|R4GFW1|R4GFW1_CHICK
Uncharacterized protein
Search

FOXB2

0.76	Forkhead box protein B2

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.49	GO:0030154	cell differentiation
0.49	GO:0009653	anatomical structure morphogenesis
0.37	GO:0097659	nucleic acid-templated transcription
0.36	GO:0010467	gene expression
0.36	GO:0034645	cellular macromolecule biosynthetic process

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|R4GFX5|R4GFX5_CHICK
Uncharacterized protein
Search

0.78	GO:0051321	meiotic cell cycle
0.54	GO:0051729	germline cell cycle switching, mitotic to meiotic cell cycle
0.51	GO:0048255	mRNA stabilization
0.51	GO:0070193	synaptonemal complex organization
0.51	GO:0051310	metaphase plate congression
0.51	GO:0048599	oocyte development
0.50	GO:0007286	spermatid development
0.48	GO:0000280	nuclear division
0.47	GO:0006302	double-strand break repair
0.43	GO:0022607	cellular component assembly

0.40	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.37	GO:0004672	protein kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008168	methyltransferase activity

0.42	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.34

GO:0008168

tr|R4GFX8|R4GFX8_CHICK
Uncharacterized protein
Search

0.69	transmembrane protein FAM155A isoform X1

0.45

GO:0098703

calcium ion import across plasma membrane

0.46

GO:0015275

stretch-activated, cation-selective, calcium channel activity

0.37	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|R4GFY1|R4GFY1_CHICK
Uncharacterized protein
Search

MED10

0.94	Mediator of RNA polymerase II transcription subunit 10

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.57	GO:0006351	transcription, DNA-templated
0.51	GO:0019827	stem cell population maintenance
0.48	GO:1905072	cardiac jelly development
0.47	GO:0045893	positive regulation of transcription, DNA-templated
0.46	GO:0036302	atrioventricular canal development
0.36	GO:0016567	protein ubiquitination
0.34	GO:0016055	Wnt signaling pathway
0.32	GO:0005975	carbohydrate metabolic process

0.79	GO:0001104	RNA polymerase II transcription cofactor activity
0.36	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0004563	beta-N-acetylhexosaminidase activity
0.33	GO:0005515	protein binding

0.77	GO:0016592	mediator complex
0.50	GO:0070847	core mediator complex
0.36	GO:0000151	ubiquitin ligase complex

0.33

EC:3.2.1.52

GO:0004563

tr|R4GFY2|R4GFY2_CHICK
Uncharacterized protein
Search

TMX4

0.92	Novel protein containing thioredoxin domain

0.68	GO:0045454	cell redox homeostasis
0.50	GO:0034976	response to endoplasmic reticulum stress
0.43	GO:0006457	protein folding
0.37	GO:0055114	oxidation-reduction process

0.48	GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds
0.42	GO:0015036	disulfide oxidoreductase activity
0.40	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0010181	FMN binding

0.46	GO:0005783	endoplasmic reticulum
0.42	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.41	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.48

EC:5.3.4

GO:0016864

tr|R4GFY3|R4GFY3_CHICK
Uncharacterized protein
Search

WDR81

0.90	WD repeat-containing protein 81

0.86	GO:0035973	aggrephagy
0.85	GO:0045022	early endosome to late endosome transport
0.84	GO:0043551	regulation of phosphatidylinositol 3-kinase activity
0.81	GO:0010923	negative regulation of phosphatase activity
0.79	GO:0050821	protein stabilization
0.73	GO:0007005	mitochondrion organization
0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.38	GO:0006468	protein phosphorylation

0.85	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding
0.85	GO:0035014	phosphatidylinositol 3-kinase regulator activity
0.38	GO:0004672	protein kinase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.86	GO:0031313	extrinsic component of endosome membrane
0.85	GO:0000421	autophagosome membrane
0.84	GO:0031901	early endosome membrane
0.82	GO:0031902	late endosome membrane
0.81	GO:0005765	lysosomal membrane
0.68	GO:0005829	cytosol
0.60	GO:0005739	mitochondrion
0.43	GO:0005789	endoplasmic reticulum membrane
0.43	GO:0005794	Golgi apparatus

tr|R4GFY8|R4GFY8_CHICK
Keratin
Search

0.83	Feather beta keratin

0.71

GO:0007010

cytoskeleton organization

0.77

GO:0005200

structural constituent of cytoskeleton

0.79

GO:0005882

intermediate filament

tr|R4GFZ2|R4GFZ2_CHICK
Neurotensin
Search

NTS

0.97	Neurotensin/neuromedin N

0.76	GO:0010469	regulation of receptor activity
0.41	GO:0050880	regulation of blood vessel size
0.37	GO:0097332	response to antipsychotic drug
0.36	GO:0051412	response to corticosterone
0.36	GO:0071285	cellular response to lithium ion
0.36	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.36	GO:0071549	cellular response to dexamethasone stimulus
0.36	GO:0001975	response to amphetamine
0.36	GO:1990090	cellular response to nerve growth factor stimulus
0.36	GO:0042220	response to cocaine

0.85

GO:0005184

neuropeptide hormone activity

0.66	GO:0005576	extracellular region
0.49	GO:0043679	axon terminus
0.40	GO:0030133	transport vesicle
0.35	GO:0043025	neuronal cell body
0.30	GO:0016020	membrane

tr|R4GFZ9|R4GFZ9_CHICK
Uncharacterized protein
Search

NR2C2AP

0.97	Nuclear receptor 2C2-associated protein isoform B

0.39	GO:0006367	transcription initiation from RNA polymerase II promoter
0.37	GO:0007155	cell adhesion
0.35	GO:0042254	ribosome biogenesis
0.34	GO:0006396	RNA processing

0.39	GO:0005540	hyaluronic acid binding
0.36	GO:0005515	protein binding
0.30	GO:0003824	catalytic activity

0.67	GO:0005654	nucleoplasm
0.42	GO:0070062	extracellular exosome
0.36	GO:0005730	nucleolus

tr|R4GG01|R4GG01_CHICK
Uncharacterized protein
Search

CPN2

0.60	Carboxypeptidase N subunit 2

0.44	GO:0007165	signal transduction
0.43	GO:0007409	axonogenesis
0.42	GO:1903077	negative regulation of protein localization to plasma membrane
0.41	GO:0046813	receptor-mediated virion attachment to host cell
0.40	GO:0030334	regulation of cell migration
0.40	GO:2000147	positive regulation of cell motility
0.39	GO:0019538	protein metabolic process
0.38	GO:0043412	macromolecule modification
0.38	GO:0051965	positive regulation of synapse assembly
0.38	GO:0016310	phosphorylation

0.42	GO:0001968	fibronectin binding
0.42	GO:0043236	laminin binding
0.41	GO:0005518	collagen binding
0.41	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.38	GO:0016301	kinase activity
0.37	GO:0005096	GTPase activator activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0031012	extracellular matrix
0.36	GO:0005829	cytosol
0.34	GO:0009505	plant-type cell wall
0.34	GO:0055044	symplast
0.34	GO:0005886	plasma membrane
0.34	GO:0005911	cell-cell junction
0.30	GO:0016021	integral component of membrane

0.39

GO:0016773

tr|R4GG02|R4GG02_CHICK
Uncharacterized protein
Search

FN3KRP

0.69	Fructosamine-3-kinase

0.56	GO:0016310	phosphorylation
0.46	GO:0030389	fructosamine metabolic process
0.43	GO:0030855	epithelial cell differentiation
0.34	GO:0043687	post-translational protein modification

0.58

GO:0016301

kinase activity

0.33

GO:0005829

cytosol

tr|R4GG09|R4GG09_CHICK
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|R4GG12|R4GG12_CHICK
Keratin
Search

0.62	Beta-keratin

0.71

GO:0007010

cytoskeleton organization

0.77

GO:0005200

structural constituent of cytoskeleton

0.79

GO:0005882

intermediate filament

tr|R4GG16|R4GG16_CHICK
Hyaluronidase
Search

HYAL3

0.72	Hyaluronidase

0.74	GO:0030214	hyaluronan catabolic process
0.64	GO:0071493	cellular response to UV-B
0.62	GO:0071347	cellular response to interleukin-1
0.60	GO:0051216	cartilage development
0.60	GO:2000355	negative regulation of ovarian follicle development
0.60	GO:2000368	positive regulation of acrosomal vesicle exocytosis
0.60	GO:0001552	ovarian follicle atresia
0.60	GO:0005975	carbohydrate metabolic process
0.60	GO:0071356	cellular response to tumor necrosis factor
0.59	GO:0007341	penetration of zona pellucida

0.85	GO:0004415	hyalurononglucosaminidase activity
0.67	GO:0033906	hyaluronoglucuronidase activity
0.53	GO:0030294	receptor signaling protein tyrosine kinase inhibitor activity
0.53	GO:0001618	virus receptor activity
0.49	GO:0005540	hyaluronic acid binding
0.49	GO:0050431	transforming growth factor beta binding
0.48	GO:0001105	RNA polymerase II transcription coactivator activity
0.48	GO:0030971	receptor tyrosine kinase binding
0.36	GO:0008080	N-acetyltransferase activity

0.58	GO:0005764	lysosome
0.57	GO:0097225	sperm midpiece
0.57	GO:0002080	acrosomal membrane
0.53	GO:0005769	early endosome
0.50	GO:0005902	microvillus
0.49	GO:0031362	anchored component of external side of plasma membrane
0.49	GO:0005783	endoplasmic reticulum
0.48	GO:0016324	apical plasma membrane
0.48	GO:0030139	endocytic vesicle
0.48	GO:0098857	membrane microdomain

0.85

EC:3.2.1.35

GO:0004415

tr|R4GG19|R4GG19_CHICK
Neurexophilin
Search

NXPH2

0.92	Neurexophilin

0.40

GO:0007218

neuropeptide signaling pathway

0.72

GO:0005102

receptor binding

0.43	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

tr|R4GG20|R4GG20_CHICK
Uncharacterized protein
Search

CFAP73

0.74	Coiled-coil domain-containing protein 42B

tr|R4GG26|R4GG26_CHICK
Uncharacterized protein
Search

ANKRD22

0.97	Ankyrin repeat domain-containing protein 22

0.43	GO:0043547	positive regulation of GTPase activity
0.33	GO:0006468	protein phosphorylation
0.32	GO:0015969	guanosine tetraphosphate metabolic process

0.44	GO:0005096	GTPase activator activity
0.36	GO:0046872	metal ion binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

tr|R4GG28|R4GG28_CHICK
Uncharacterized protein
Search

0.77	Putative tumor suppressor protein MN1

0.63	GO:0036072	direct ossification
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.37	GO:0007275	multicellular organism development
0.36	GO:0015914	phospholipid transport
0.35	GO:0097659	nucleic acid-templated transcription
0.34	GO:0010467	gene expression
0.34	GO:0034645	cellular macromolecule biosynthetic process

0.36

GO:0005548

phospholipid transporter activity

0.32	GO:0005622	intracellular
0.30	GO:0044425	membrane part

tr|R4GG32|R4GG32_CHICK
Uncharacterized protein
Search

0.77	MKRN2 opposite strand protein (Fragment)

0.30

GO:0044425

membrane part

tr|R4GG35|R4GG35_CHICK
Uncharacterized protein
Search

NOVA1

0.94	NOVA alternative splicing regulator 1

0.75	GO:0000398	mRNA splicing, via spliceosome
0.49	GO:0051252	regulation of RNA metabolic process

0.63

GO:0003729

mRNA binding

0.63

GO:0005730

nucleolus

tr|R4GG37|R4GG37_CHICK
Uncharacterized protein
Search

0.95	Zinc finger protein 469

0.35	GO:0010469	regulation of receptor activity
0.33	GO:0097659	nucleic acid-templated transcription
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression
0.32	GO:0010467	gene expression
0.32	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.37	GO:0046872	metal ion binding
0.35	GO:0005179	hormone activity

0.34	GO:0005576	extracellular region
0.33	GO:0005634	nucleus

tr|R4GG38|R4GG38_CHICK
Uncharacterized protein
Search

VGLL4

0.92	Vestigial like 4 (Drosophila)

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.39	GO:0035329	hippo signaling

0.33	GO:0005622	intracellular
0.30	GO:0044425	membrane part

tr|R4GG44|R4GG44_CHICK
Uncharacterized protein
Search

LRIT3

0.75	Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3

0.72	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway
0.65	GO:0007601	visual perception
0.36	GO:0050896	response to stimulus
0.34	GO:0018298	protein-chromophore linkage
0.33	GO:0023052	signaling
0.33	GO:0007154	cell communication

0.34	GO:0009881	photoreceptor activity
0.34	GO:0004930	G-protein coupled receptor activity

0.42	GO:0043204	perikaryon
0.41	GO:0030425	dendrite
0.40	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

tr|R4GG47|R4GG47_CHICK
Uncharacterized protein
Search

SLC35F1

0.90	Solute carrier family 35, member F2 isoform B

0.55

GO:0055085

transmembrane transport

0.57

GO:0022857

transmembrane transporter activity

0.30

GO:0044425

membrane part

tr|R4GG51|R4GG51_CHICK
Uncharacterized protein
Search

SLC30A10

0.83	Zinc transporter 10

0.61	GO:0098655	cation transmembrane transport
0.57	GO:1905802	regulation of cellular response to manganese ion
0.57	GO:0071579	regulation of zinc ion transport
0.56	GO:2000773	negative regulation of cellular senescence
0.55	GO:1903427	negative regulation of reactive oxygen species biosynthetic process
0.54	GO:1904385	cellular response to angiotensin
0.54	GO:0007173	epidermal growth factor receptor signaling pathway
0.53	GO:0043524	negative regulation of neuron apoptotic process
0.53	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.52	GO:0006828	manganese ion transport

0.61	GO:0008324	cation transmembrane transporter activity
0.41	GO:0015318	inorganic molecular entity transmembrane transporter activity
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding

0.52	GO:0055037	recycling endosome
0.51	GO:0005769	early endosome
0.39	GO:0005886	plasma membrane
0.38	GO:0000324	fungal-type vacuole
0.37	GO:0098852	lytic vacuole membrane
0.36	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

tr|R4GG54|R4GG54_CHICK
Uncharacterized protein
Search

tr|R4GG58|R4GG58_CHICK
Uncharacterized protein
Search

OTX1

0.97	Orthodenticle homeobox 1

0.70	GO:0048852	diencephalon morphogenesis
0.67	GO:0042472	inner ear morphogenesis
0.67	GO:0030901	midbrain development
0.65	GO:0022037	metencephalon development
0.64	GO:0009952	anterior/posterior pattern specification
0.60	GO:0006366	transcription by RNA polymerase II
0.60	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0060875	lateral semicircular canal development
0.45	GO:0003406	retinal pigment epithelium development
0.41	GO:0071542	dopaminergic neuron differentiation

0.65	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.65	GO:0043565	sequence-specific DNA binding
0.62	GO:0001012	RNA polymerase II regulatory region DNA binding
0.58	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.40	GO:0030426	growth cone
0.36	GO:0043234	protein complex

tr|R4GG61|R4GG61_CHICK
Uncharacterized protein
Search

SCEL

0.71

Sciellin

0.53	GO:0030216	keratinocyte differentiation
0.53	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.53	GO:0009612	response to mechanical stimulus
0.38	GO:0009792	embryo development ending in birth or egg hatching

0.54	GO:0046872	metal ion binding
0.36	GO:0051015	actin filament binding

0.51	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0015629	actin cytoskeleton

tr|R4GG62|R4GG62_CHICK
Uncharacterized protein
Search

CNKSR3

0.97	Connector enhancer of kinase suppressor of ras 3

0.70	GO:0009966	regulation of signal transduction
0.48	GO:0016310	phosphorylation
0.39	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.39	GO:0010765	positive regulation of sodium ion transport
0.37	GO:2000649	regulation of sodium ion transmembrane transporter activity
0.37	GO:0032414	positive regulation of ion transmembrane transporter activity
0.36	GO:1904064	positive regulation of cation transmembrane transport
0.36	GO:0023057	negative regulation of signaling
0.36	GO:0010648	negative regulation of cell communication
0.36	GO:0048585	negative regulation of response to stimulus

0.50	GO:0016301	kinase activity
0.34	GO:0005515	protein binding

0.49	GO:0005737	cytoplasm
0.43	GO:0014069	postsynaptic density
0.38	GO:0098590	plasma membrane region
0.37	GO:0045177	apical part of cell
0.35	GO:0043025	neuronal cell body
0.34	GO:0043005	neuron projection
0.33	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

tr|R4GG64|R4GG64_CHICK
Uncharacterized protein
Search

DCBLD1

0.91	Coagulation factor VIII

0.36	GO:0070527	platelet aggregation
0.35	GO:0006352	DNA-templated transcription, initiation
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process

0.50	GO:0070492	oligosaccharide binding
0.36	GO:0046982	protein heterodimerization activity
0.33	GO:0003735	structural constituent of ribosome

0.36	GO:0005669	transcription factor TFIID complex
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

tr|R4GG67|R4GG67_CHICK
Uncharacterized protein
Search

SMCO4

0.97	Single-pass membrane and coiled-coil domain-containing protein 4

0.34

GO:0005515

protein binding

0.30

GO:0044425

membrane part

tr|R4GG68|R4GG68_CHICK
Uncharacterized protein
Search

NRN1

0.79

Neuritin

0.74	GO:0007399	nervous system development
0.36	GO:0015074	DNA integration

0.33

GO:0003676

nucleic acid binding

0.30

GO:0044425

membrane part

tr|R4GG74|R4GG74_CHICK
Uncharacterized protein
Search

0.66	Cytosolic phospholipase A2 epsilon

0.79

GO:0009395

phospholipid catabolic process

0.80	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.80	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.77	GO:0004623	phospholipase A2 activity
0.52	GO:0046872	metal ion binding

0.47	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.77

EC:3.1.1.4

GO:0004623

tr|R4GG75|R4GG75_CHICK
Uncharacterized protein
Search

HGNC:24955

0.97	Neuronal vesicle trafficking-associated protein 2

0.85	GO:0007212	dopamine receptor signaling pathway
0.83	GO:0048268	clathrin coat assembly
0.50	GO:0016197	endosomal transport
0.47	GO:0099627	neurotransmitter receptor cycle
0.46	GO:1903540	establishment of protein localization to postsynaptic membrane
0.46	GO:0098877	neurotransmitter receptor transport to plasma membrane
0.46	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels
0.46	GO:0042982	amyloid precursor protein metabolic process
0.45	GO:0001881	receptor recycling
0.45	GO:0097120	receptor localization to synapse

0.85	GO:0032051	clathrin light chain binding
0.34	GO:0005102	receptor binding
0.34	GO:0003730	mRNA 3'-UTR binding
0.34	GO:0045182	translation regulator activity
0.32	GO:0003677	DNA binding

0.51	GO:0005768	endosome
0.49	GO:1990674	Golgi cis cisterna membrane
0.45	GO:0016328	lateral plasma membrane
0.44	GO:0030659	cytoplasmic vesicle membrane
0.43	GO:0045211	postsynaptic membrane
0.43	GO:0098805	whole membrane
0.41	GO:0043202	lysosomal lumen
0.41	GO:0005783	endoplasmic reticulum
0.40	GO:0032588	trans-Golgi network membrane
0.40	GO:0030425	dendrite

tr|R4GG86|R4GG86_CHICK
Uncharacterized protein
Search

IRS2

0.77	Insulin receptor substrate 2

0.78	GO:0008286	insulin receptor signaling pathway
0.77	GO:0032000	positive regulation of fatty acid beta-oxidation
0.76	GO:0045725	positive regulation of glycogen biosynthetic process
0.74	GO:0046326	positive regulation of glucose import
0.69	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport
0.69	GO:0050796	regulation of insulin secretion
0.66	GO:0007420	brain development
0.64	GO:0002903	negative regulation of B cell apoptotic process
0.63	GO:0002053	positive regulation of mesenchymal cell proliferation
0.62	GO:0030890	positive regulation of B cell proliferation

0.79	GO:0043548	phosphatidylinositol 3-kinase binding
0.76	GO:0005158	insulin receptor binding
0.58	GO:0005159	insulin-like growth factor receptor binding
0.57	GO:0019901	protein kinase binding
0.55	GO:0001784	phosphotyrosine residue binding
0.54	GO:0004871	signal transducer activity
0.49	GO:0071889	14-3-3 protein binding
0.47	GO:0019903	protein phosphatase binding
0.46	GO:0019904	protein domain specific binding
0.41	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity

0.62	GO:0005829	cytosol
0.54	GO:0005901	caveola
0.47	GO:0043234	protein complex
0.45	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.41	EC:2.7.1.153	GO:0046934
0.41	KEGG:R04545	GO:0046934

tr|R4GGA2|R4GGA2_CHICK
Solute carrier organic anion transporter family member
Search

SLCO4C1

0.61	Solute carrier organic anion transporter family member

0.56	GO:0006811	ion transport
0.55	GO:0055085	transmembrane transport
0.44	GO:0071702	organic substance transport
0.39	GO:0007283	spermatogenesis
0.38	GO:0030154	cell differentiation
0.37	GO:0007275	multicellular organism development
0.36	GO:0043312	neutrophil degranulation
0.34	GO:0070327	thyroid hormone transport
0.33	GO:0007588	excretion

0.56

GO:0005215

transporter activity

0.53	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0035579	specific granule membrane
0.36	GO:0035577	azurophil granule membrane
0.30	GO:0016021	integral component of membrane

tr|R4GGA4|R4GGA4_CHICK
Uncharacterized protein
Search

SEZ6

0.97	Seizure protein 6

0.55	GO:0060074	synapse maturation
0.54	GO:2000171	negative regulation of dendrite development
0.54	GO:0090036	regulation of protein kinase C signaling
0.53	GO:0021680	cerebellar Purkinje cell layer development
0.53	GO:1900006	positive regulation of dendrite development
0.52	GO:0008344	adult locomotory behavior
0.50	GO:0060079	excitatory postsynaptic potential

0.55	GO:0097440	apical dendrite
0.53	GO:0043198	dendritic shaft
0.53	GO:0043197	dendritic spine
0.51	GO:0043025	neuronal cell body
0.50	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0005615	extracellular space
0.46	GO:0005783	endoplasmic reticulum
0.34	GO:0030054	cell junction
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|R4GGA5|R4GGA5_CHICK
Uncharacterized protein
Search

XRCC2

0.93	DNA repair protein XRCC2

0.77	GO:0000724	double-strand break repair via homologous recombination
0.46	GO:2000269	regulation of fibroblast apoptotic process
0.46	GO:0042148	strand invasion
0.46	GO:0010165	response to X-ray
0.46	GO:0010332	response to gamma radiation
0.45	GO:0001756	somitogenesis
0.45	GO:0035264	multicellular organism growth
0.45	GO:0043524	negative regulation of neuron apoptotic process
0.44	GO:0007098	centrosome cycle
0.44	GO:0001701	in utero embryonic development

0.69	GO:0008094	DNA-dependent ATPase activity
0.55	GO:0003677	DNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0000150	recombinase activity
0.39	GO:0004520	endodeoxyribonuclease activity
0.36	GO:0005515	protein binding

0.85	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex
0.74	GO:0005657	replication fork
0.43	GO:0005813	centrosome
0.41	GO:0005654	nucleoplasm
0.33	GO:0005737	cytoplasm

tr|R4GGA6|R4GGA6_CHICK
Uncharacterized protein
Search

AP1AR

0.97	AP-1 complex-associated regulatory protein isoform A

0.86	GO:0048203	vesicle targeting, trans-Golgi to endosome
0.85	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading
0.83	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation
0.81	GO:2000146	negative regulation of cell motility
0.59	GO:0001920	negative regulation of receptor recycling
0.47	GO:0034613	cellular protein localization
0.34	GO:0015031	protein transport
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.86	GO:0035650	AP-1 adaptor complex binding
0.57	GO:0019894	kinesin binding
0.34	GO:0071933	Arp2/3 complex binding
0.32	GO:0003676	nucleic acid binding

0.67	GO:0005829	cytosol
0.52	GO:0005768	endosome
0.51	GO:0030133	transport vesicle
0.49	GO:0005794	Golgi apparatus

tr|R4GGA9|R4GGA9_CHICK
Uncharacterized protein
Search

0.10	Transmembrane protein 115 (Fragment)

0.81	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.53	GO:0043413	macromolecule glycosylation
0.53	GO:0009101	glycoprotein biosynthetic process
0.45	GO:0036211	protein modification process
0.43	GO:0044267	cellular protein metabolic process
0.35	GO:0001302	replicative cell aging
0.35	GO:0008285	negative regulation of cell proliferation
0.35	GO:0006888	ER to Golgi vesicle-mediated transport
0.34	GO:0015031	protein transport

0.52	GO:0042802	identical protein binding
0.33	GO:0004386	helicase activity

0.56	GO:0017119	Golgi transport complex
0.56	GO:0032580	Golgi cisterna membrane
0.46	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|R4GGB2|R4GGB2_CHICK
Glutathione peroxidase
Search

GPX8

0.46	Glutathione peroxidase

0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.53	GO:0055114	oxidation-reduction process
0.34	GO:0033554	cellular response to stress

0.79	GO:0004602	glutathione peroxidase activity
0.38	GO:0004096	catalase activity
0.33	GO:0047066	phospholipid-hydroperoxide glutathione peroxidase activity
0.32	GO:0005515	protein binding

0.37	GO:0005783	endoplasmic reticulum
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0042651	thylakoid membrane
0.33	GO:0009507	chloroplast
0.33	GO:0005576	extracellular region
0.32	GO:0031975	envelope
0.30	GO:0044425	membrane part

0.79

EC:1.11.1.9

GO:0004602

tr|R4GGB8|R4GGB8_CHICK
Uncharacterized protein
Search

GAS2L3

0.90	Growth arrest specific 2 like 3

0.64	GO:0006915	apoptotic process
0.62	GO:0000226	microtubule cytoskeleton organization
0.60	GO:0030036	actin cytoskeleton organization
0.46	GO:0021923	cell proliferation in hindbrain ventricular zone
0.43	GO:0021591	ventricular system development
0.36	GO:0007050	cell cycle arrest
0.35	GO:0008360	regulation of cell shape

0.74	GO:0008017	microtubule binding
0.61	GO:0003779	actin binding

0.69	GO:0005856	cytoskeleton
0.41	GO:0099512	supramolecular fiber
0.37	GO:0044446	intracellular organelle part
0.37	GO:0043234	protein complex
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|R4GGB9|R4GGB9_CHICK
Cysteine-rich DPF motif domain-containing protein 1
Search

CDPF1

0.97	Cysteine-rich DPF motif domain-containing protein 1

0.46	GO:0007050	cell cycle arrest
0.45	GO:0071901	negative regulation of protein serine/threonine kinase activity

0.47	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.40	GO:0005515	protein binding
0.34	GO:0016740	transferase activity

0.39	GO:0005634	nucleus
0.30	GO:0044425	membrane part

0.34

EC:2

GO:0016740

tr|R4GGD0|R4GGD0_CHICK
Uncharacterized protein
Search

OTUD1

0.94	OTU domain-containing protein 1

0.84	GO:0070536	protein K63-linked deubiquitination
0.37	GO:0043043	peptide biosynthetic process
0.35	GO:0010467	gene expression
0.35	GO:0009059	macromolecule biosynthetic process

0.77	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.38	GO:0019843	rRNA binding
0.38	GO:0003735	structural constituent of ribosome
0.36	GO:0030554	adenyl nucleotide binding
0.35	GO:0032555	purine ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.37

GO:0005840

ribosome

tr|R4GGD2|R4GGD2_CHICK
Uncharacterized protein
Search

TMEM38B

0.88	Trimeric intracellular cation channel type B-A

0.60	GO:0015672	monovalent inorganic cation transport
0.59	GO:0098655	cation transmembrane transport
0.42	GO:0030001	metal ion transport
0.41	GO:0098660	inorganic ion transmembrane transport
0.30	GO:0009987	cellular process

0.71	GO:0005261	cation channel activity
0.45	GO:0015079	potassium ion transmembrane transporter activity
0.42	GO:0022839	ion gated channel activity
0.42	GO:0008381	mechanosensitive ion channel activity
0.34	GO:0005515	protein binding

0.44	GO:0005789	endoplasmic reticulum membrane
0.43	GO:0016529	sarcoplasmic reticulum
0.42	GO:0031965	nuclear membrane
0.40	GO:0098588	bounding membrane of organelle
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

tr|R4GGE3|R4GGE3_CHICK
Uncharacterized protein
Search

LACTBL1

0.97	Lactamase beta like 1

0.40

GO:0031284

positive regulation of guanylate cyclase activity

0.40	GO:0030250	guanylate cyclase activator activity
0.32	GO:0016787	hydrolase activity

0.36	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

0.32

GO:0016787

tr|R4GGE4|R4GGE4_CHICK
Uncharacterized protein
Search

ARID3A

0.95	AT-rich interactive domain-containing protein 3A

0.53	GO:0006366	transcription by RNA polymerase II
0.53	GO:0045944	positive regulation of transcription by RNA polymerase II
0.36	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
0.35	GO:0007275	multicellular organism development
0.34	GO:0007186	G-protein coupled receptor signaling pathway

0.55	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.55	GO:0003677	DNA binding
0.53	GO:0001067	regulatory region nucleic acid binding
0.51	GO:0003682	chromatin binding
0.50	GO:0042803	protein homodimerization activity
0.34	GO:0004930	G-protein coupled receptor activity

0.61	GO:0005634	nucleus
0.52	GO:0045121	membrane raft
0.47	GO:0005829	cytosol
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|R4GGE5|R4GGE5_CHICK
Uncharacterized protein
Search

ALX1

0.97	ALX homeobox protein 1

0.83	GO:0001755	neural crest cell migration
0.64	GO:0048704	embryonic skeletal system morphogenesis
0.60	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.58	GO:0030326	embryonic limb morphogenesis
0.58	GO:0060021	palate development
0.58	GO:0001843	neural tube closure
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0009952	anterior/posterior pattern specification
0.56	GO:0010468	regulation of gene expression

0.63	GO:0043565	sequence-specific DNA binding
0.59	GO:0003700	DNA binding transcription factor activity
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0046982	protein heterodimerization activity
0.52	GO:0003690	double-stranded DNA binding
0.38	GO:0042803	protein homodimerization activity
0.35	GO:0003714	transcription corepressor activity

0.60	GO:0005634	nucleus
0.52	GO:0005667	transcription factor complex
0.51	GO:0005794	Golgi apparatus
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part

tr|R4GGE6|R4GGE6_CHICK
Uncharacterized protein
Search

TMEM26

0.97	Transmembrane protein 26

0.33	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.32	GO:0016779	nucleotidyltransferase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

0.32

EC:2.7.7

GO:0016779

tr|R4GGF1|R4GGF1_CHICK
Uncharacterized protein
Search

LRG1

0.83	Leucine rich alpha-2-glycoprotein 1

0.66	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.64	GO:0001938	positive regulation of endothelial cell proliferation
0.64	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.63	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
0.63	GO:0045766	positive regulation of angiogenesis
0.60	GO:0050873	brown fat cell differentiation
0.43	GO:0071559	response to transforming growth factor beta
0.43	GO:0043312	neutrophil degranulation
0.41	GO:1903828	negative regulation of cellular protein localization
0.40	GO:0006508	proteolysis

0.65	GO:0005160	transforming growth factor beta receptor binding
0.44	GO:0019834	phospholipase A2 inhibitor activity
0.43	GO:0004180	carboxypeptidase activity
0.40	GO:0001968	fibronectin binding
0.40	GO:0043236	laminin binding
0.39	GO:0005518	collagen binding
0.36	GO:0044325	ion channel binding
0.36	GO:0004252	serine-type endopeptidase activity
0.36	GO:0005262	calcium channel activity
0.36	GO:0019901	protein kinase binding

0.57	GO:0005615	extracellular space
0.46	GO:0043231	intracellular membrane-bounded organelle
0.44	GO:1904724	tertiary granule lumen
0.44	GO:0035580	specific granule lumen
0.43	GO:1904813	ficolin-1-rich granule lumen
0.42	GO:1903561	extracellular vesicle
0.37	GO:0031012	extracellular matrix
0.37	GO:0002133	polycystin complex
0.37	GO:0009986	cell surface
0.36	GO:0016323	basolateral plasma membrane

0.36

GO:0004252

tr|R4GGF3|R4GGF3_CHICK
Uncharacterized protein
Search

GLIPR2

0.88	Golgi-associated plant pathogenesis-related protein 1

0.52	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.51	GO:0010634	positive regulation of epithelial cell migration
0.51	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.34	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.34	GO:0007186	G-protein coupled receptor signaling pathway

0.48	GO:0042803	protein homodimerization activity
0.34	GO:0004984	olfactory receptor activity
0.34	GO:0004930	G-protein coupled receptor activity

0.65	GO:0005576	extracellular region
0.47	GO:0000139	Golgi membrane
0.35	GO:0031982	vesicle
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|R4GGF6|R4GGF6_CHICK
Uncharacterized protein
Search

SDCBP2

0.92	Putative pdz domain containing protein found in a variety of eumetazoan signaling molecules

0.71	GO:0007268	chemical synaptic transmission
0.67	GO:0030036	actin cytoskeleton organization
0.58	GO:0035556	intracellular signal transduction
0.54	GO:0008283	cell proliferation
0.48	GO:0030307	positive regulation of cell growth
0.48	GO:0030335	positive regulation of cell migration
0.47	GO:0008284	positive regulation of cell proliferation
0.37	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.37	GO:0007399	nervous system development
0.37	GO:0042246	tissue regeneration

0.58	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.57	GO:0008022	protein C-terminus binding
0.53	GO:0042803	protein homodimerization activity
0.52	GO:0046982	protein heterodimerization activity
0.52	GO:0005137	interleukin-5 receptor binding
0.41	GO:0045545	syndecan binding
0.37	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.36	GO:0050839	cell adhesion molecule binding
0.35	GO:0042043	neurexin family protein binding
0.35	GO:0005109	frizzled binding

0.55	GO:0016607	nuclear speck
0.53	GO:0005895	interleukin-5 receptor complex
0.51	GO:0005730	nucleolus
0.48	GO:0031965	nuclear membrane
0.44	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome
0.35	GO:0035578	azurophil granule lumen
0.35	GO:0072562	blood microparticle
0.35	GO:0042470	melanosome
0.34	GO:0005925	focal adhesion

tr|R4GGF7|R4GGF7_CHICK
Uncharacterized protein
Search

LYRM4

0.92	LYR motif-containing protein 4

0.41	GO:0048741	skeletal muscle fiber development
0.39	GO:0019521	D-gluconate metabolic process
0.38	GO:0006098	pentose-phosphate shunt
0.37	GO:0016226	iron-sulfur cluster assembly
0.34	GO:0055114	oxidation-reduction process

0.39	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity
0.38	GO:0031071	cysteine desulfurase activity

0.60	GO:0005739	mitochondrion
0.45	GO:0005634	nucleus
0.43	GO:0031974	membrane-enclosed lumen
0.40	GO:1990221	L-cysteine desulfurase complex
0.40	GO:0044446	intracellular organelle part
0.38	GO:0019898	extrinsic component of membrane
0.35	GO:0031090	organelle membrane
0.35	GO:0031975	envelope

0.39

EC:1.1.1.44

GO:0004616

tr|R4GGF8|R4GGF8_CHICK
Uncharacterized protein
Search

CDK5R1

0.95	Cyclin-dependent kinase 5 activator

0.80	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.60	GO:0021722	superior olivary nucleus maturation
0.58	GO:0021819	layer formation in cerebral cortex
0.56	GO:0021766	hippocampus development
0.55	GO:0021549	cerebellum development
0.55	GO:0001764	neuron migration
0.54	GO:0042501	serine phosphorylation of STAT protein
0.53	GO:0007158	neuron cell-cell adhesion
0.53	GO:0061001	regulation of dendritic spine morphogenesis
0.53	GO:0090314	positive regulation of protein targeting to membrane

0.86	GO:0016534	cyclin-dependent protein kinase 5 activator activity
0.53	GO:0035255	ionotropic glutamate receptor binding
0.51	GO:0002020	protease binding
0.50	GO:0016301	kinase activity
0.49	GO:0019901	protein kinase binding
0.48	GO:0051015	actin filament binding
0.39	GO:0045296	cadherin binding
0.39	GO:0046875	ephrin receptor binding
0.37	GO:0005509	calcium ion binding
0.36	GO:0043014	alpha-tubulin binding

0.86	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex
0.50	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0005654	nucleoplasm
0.40	GO:0014069	postsynaptic density
0.39	GO:0043197	dendritic spine
0.39	GO:0031594	neuromuscular junction
0.39	GO:0030426	growth cone
0.39	GO:0043025	neuronal cell body
0.39	GO:0043292	contractile fiber
0.39	GO:0030424	axon

0.33

GO:0016773

tr|R4GGG3|R4GGG3_CHICK
Uncharacterized protein
Search

SEMA4G

0.97	Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ga

0.52	GO:0050919	negative chemotaxis
0.41	GO:0021535	cell migration in hindbrain
0.41	GO:0032874	positive regulation of stress-activated MAPK cascade
0.41	GO:0001843	neural tube closure
0.41	GO:0021549	cerebellum development
0.40	GO:0042692	muscle cell differentiation
0.40	GO:0071526	semaphorin-plexin signaling pathway

0.53

GO:0038191

neuropilin binding

0.46	GO:0005615	extracellular space
0.41	GO:0030672	synaptic vesicle membrane
0.40	GO:0014069	postsynaptic density
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|R4GGG4|R4GGG4_CHICK
Uncharacterized protein
Search

CYP2U1

0.97	Cytochrome P450 family 2 subfamily U member 1

0.53

GO:0055114

oxidation-reduction process

0.77	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.53	GO:0008395	steroid hydroxylase activity

0.30

GO:0031224

intrinsic component of membrane

0.77

EC:1.14.14

GO:0016712

tr|R4GGG6|R4GGG6_CHICK
Uncharacterized protein
Search

NPBWR2

0.97	Neuropeptides B and W receptor 2

0.77	GO:0007218	neuropeptide signaling pathway
0.51	GO:0038169	somatostatin receptor signaling pathway
0.50	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.48	GO:0007268	chemical synaptic transmission
0.47	GO:0009755	hormone-mediated signaling pathway
0.40	GO:0019222	regulation of metabolic process
0.39	GO:0038003	opioid receptor signaling pathway
0.35	GO:0071407	cellular response to organic cyclic compound
0.35	GO:0051384	response to glucocorticoid
0.35	GO:0050796	regulation of insulin secretion

0.82	GO:0008188	neuropeptide receptor activity
0.53	GO:0042923	neuropeptide binding
0.39	GO:0004985	opioid receptor activity
0.35	GO:0005515	protein binding
0.33	GO:0060182	apelin receptor activity
0.33	GO:0016494	C-X-C chemokine receptor activity
0.32	GO:0004427	inorganic diphosphatase activity
0.31	GO:0032550	purine ribonucleoside binding
0.31	GO:0032561	guanyl ribonucleotide binding
0.31	GO:0000287	magnesium ion binding

0.48	GO:0043005	neuron projection
0.44	GO:0005887	integral component of plasma membrane
0.31	GO:0005794	Golgi apparatus
0.31	GO:0005783	endoplasmic reticulum

0.32	EC:3.6.1.1	GO:0004427
0.32	KEGG:R00004	GO:0004427

tr|R4GGG9|R4GGG9_CHICK
Uncharacterized protein
Search

0.46	GO:0006468	protein phosphorylation
0.43	GO:0006325	chromatin organization
0.42	GO:0009910	negative regulation of flower development
0.41	GO:0006368	transcription elongation from RNA polymerase II promoter
0.41	GO:0006397	mRNA processing
0.40	GO:0065004	protein-DNA complex assembly
0.40	GO:0006323	DNA packaging
0.40	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.40	GO:0006754	ATP biosynthetic process
0.39	GO:0006479	protein methylation

0.47	GO:0003779	actin binding
0.46	GO:0004674	protein serine/threonine kinase activity
0.43	GO:0005199	structural constituent of cell wall
0.42	GO:0032559	adenyl ribonucleotide binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0003723	RNA binding
0.38	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.38	GO:0015078	hydrogen ion transmembrane transporter activity
0.37	GO:0003677	DNA binding

0.45	GO:0035145	exon-exon junction complex
0.42	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.41	GO:0016593	Cdc73/Paf1 complex
0.40	GO:0000786	nucleosome
0.38	GO:0005769	early endosome
0.37	GO:0005856	cytoskeleton
0.30	GO:0016021	integral component of membrane

0.46

GO:0004674

tr|R4GGI3|R4GGI3_CHICK
Uncharacterized protein
Search

MLPH

0.85	Melanophilin transcript variant 1

0.69	GO:0006886	intracellular protein transport
0.44	GO:0030050	vesicle transport along actin filament
0.35	GO:0051875	pigment granule localization
0.34	GO:0010469	regulation of receptor activity
0.33	GO:0030318	melanocyte differentiation
0.33	GO:0006260	DNA replication

0.81	GO:0017137	Rab GTPase binding
0.51	GO:0017022	myosin binding
0.48	GO:0030674	protein binding, bridging
0.40	GO:0003779	actin binding
0.34	GO:0005179	hormone activity
0.33	GO:0051010	microtubule plus-end binding
0.32	GO:0046872	metal ion binding

0.48	GO:0030425	dendrite
0.48	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0030864	cortical actin cytoskeleton
0.33	GO:0016461	unconventional myosin complex
0.33	GO:0035371	microtubule plus-end
0.33	GO:0097517	contractile actin filament bundle
0.33	GO:0042470	melanosome
0.33	GO:0042641	actomyosin
0.33	GO:0005815	microtubule organizing center
0.33	GO:0005634	nucleus

tr|R4GGJ0|R4GGJ0_CHICK
Uncharacterized protein
Search

RPS16

0.55	Ribosomal protein S16

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.50	GO:1990830	cellular response to leukemia inhibitory factor
0.49	GO:0042274	ribosomal small subunit biogenesis
0.47	GO:0016072	rRNA metabolic process
0.39	GO:0097421	liver regeneration
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.64	GO:0003735	structural constituent of ribosome
0.43	GO:0003723	RNA binding
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0005515	protein binding
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.48	GO:0044445	cytosolic part
0.42	GO:0044446	intracellular organelle part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle

0.33

GO:0016705

tr|R4GGJ1|R4GGJ1_CHICK
Uncharacterized protein
Search

UBTD1

0.96	Ubiquitin domain-containing protein 1

0.80

GO:0043130

ubiquitin binding

0.33

GO:0005737

cytoplasm

tr|R4GGK3|R4GGK3_CHICK
Uncharacterized protein
Search

0.96	Parathyroid hormone 4

0.85	GO:0032330	regulation of chondrocyte differentiation
0.76	GO:0010469	regulation of receptor activity
0.58	GO:0002076	osteoblast development
0.55	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.42	GO:0007218	neuropeptide signaling pathway

0.79	GO:0005179	hormone activity
0.58	GO:0051428	peptide hormone receptor binding

0.66	GO:0005576	extracellular region
0.37	GO:0005622	intracellular

tr|R4GGK5|R4GGK5_CHICK
Uncharacterized protein
Search

GLOD5

0.97	Glyoxalase domain-containing protein 5

0.51

GO:0055114

oxidation-reduction process

0.67	GO:0051213	dioxygenase activity
0.40	GO:0016829	lyase activity
0.40	GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
0.35	GO:0016787	hydrolase activity
0.34	GO:0046872	metal ion binding

0.40