Queries 15001 to 16000

GO:0036459

sp|O57476|CDC37_CHICK
Hsp90 co-chaperone Cdc37
Search

CDC37

0.96	Cell division cycle 37

0.66	GO:0060330	regulation of response to interferon-gamma
0.64	GO:0098779	positive regulation of mitophagy in response to mitochondrial depolarization
0.57	GO:0060338	regulation of type I interferon-mediated signaling pathway
0.55	GO:0045859	regulation of protein kinase activity
0.53	GO:0010608	posttranscriptional regulation of gene expression
0.52	GO:0050821	protein stabilization
0.50	GO:0051301	cell division
0.47	GO:0006457	protein folding

0.78	GO:0019901	protein kinase binding
0.65	GO:0097110	scaffold protein binding
0.63	GO:0031072	heat shock protein binding
0.57	GO:0019887	protein kinase regulator activity
0.51	GO:0051087	chaperone binding
0.48	GO:0051082	unfolded protein binding

0.66	GO:1990565	HSP90-CDC37 chaperone complex
0.54	GO:0005829	cytosol

sp|O57535|NDK_CHICK
Nucleoside diphosphate kinase
Search

0.47	Nucleoside diphosphate kinase B

0.79	GO:0006228	UTP biosynthetic process
0.79	GO:0006183	GTP biosynthetic process
0.75	GO:0046036	CTP metabolic process
0.70	GO:0006165	nucleoside diphosphate phosphorylation
0.47	GO:0050679	positive regulation of epithelial cell proliferation
0.47	GO:0042981	regulation of apoptotic process
0.45	GO:0007595	lactation
0.44	GO:0043388	positive regulation of DNA binding
0.44	GO:2000026	regulation of multicellular organismal development
0.42	GO:0045597	positive regulation of cell differentiation

0.79	GO:0004550	nucleoside diphosphate kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.45	GO:0043024	ribosomal small subunit binding
0.41	GO:0042802	identical protein binding
0.41	GO:0019215	intermediate filament binding
0.41	GO:0004536	deoxyribonuclease activity
0.40	GO:0046872	metal ion binding

0.49	GO:0001726	ruffle
0.45	GO:0043209	myelin sheath
0.44	GO:0031256	leading edge membrane
0.43	GO:0031253	cell projection membrane
0.43	GO:0030027	lamellipodium
0.42	GO:0005634	nucleus
0.41	GO:0005829	cytosol
0.41	GO:0005925	focal adhesion
0.39	GO:0005739	mitochondrion
0.39	GO:0070062	extracellular exosome

0.79

EC:2.7.4.6

GO:0004550

sp|O57579|AMPN_CHICK
Aminopeptidase Ey
Search

ANPEP

0.52	Aminopeptidase Ey

0.60	GO:0006508	proteolysis
0.48	GO:0008217	regulation of blood pressure
0.46	GO:0043171	peptide catabolic process
0.45	GO:0007267	cell-cell signaling
0.42	GO:0001525	angiogenesis
0.40	GO:0007165	signal transduction
0.40	GO:0030154	cell differentiation
0.37	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.37	GO:0044409	entry into host
0.37	GO:0019058	viral life cycle

0.70	GO:0004177	aminopeptidase activity
0.66	GO:0008237	metallopeptidase activity
0.62	GO:0008270	zinc ion binding
0.46	GO:0042277	peptide binding
0.41	GO:0104005	hijacked molecular function
0.33	GO:0004872	receptor activity

0.53	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.52	GO:0070062	extracellular exosome
0.51	GO:0009897	external side of plasma membrane
0.40	GO:0005765	lysosomal membrane
0.36	GO:0012506	vesicle membrane
0.35	GO:0031983	vesicle lumen
0.35	GO:0030141	secretory granule
0.34	GO:0044433	cytoplasmic vesicle part
0.30	GO:0016021	integral component of membrane

0.70

EC:3.4.11

GO:0004177

sp|O57598|ATOH7_CHICK
Protein atonal homolog 7
Search

ATOH7

0.97	Atonal bHLH transcription factor 7

0.78	GO:0003407	neural retina development
0.58	GO:0007399	nervous system development
0.55	GO:0009649	entrainment of circadian clock
0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.53	GO:0007623	circadian rhythm
0.50	GO:0030154	cell differentiation
0.48	GO:0048839	inner ear development
0.48	GO:0008544	epidermis development

0.68	GO:0046983	protein dimerization activity
0.44	GO:0001012	RNA polymerase II regulatory region DNA binding
0.42	GO:0031490	chromatin DNA binding
0.42	GO:0043565	sequence-specific DNA binding
0.42	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0003690	double-stranded DNA binding
0.30	GO:0003824	catalytic activity

0.39

GO:0005634

nucleus

sp|O57601|HMX3_CHICK
Homeobox protein HMX3
Search

HMX3

0.93	Homeobox protein HMX3-A

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0042472	inner ear morphogenesis
0.50	GO:0050885	neuromuscular process controlling balance
0.50	GO:0007399	nervous system development
0.49	GO:0007566	embryo implantation
0.48	GO:0060135	maternal process involved in female pregnancy
0.48	GO:0060322	head development
0.42	GO:0030154	cell differentiation

0.64	GO:0043565	sequence-specific DNA binding
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003690	double-stranded DNA binding
0.35	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|O57604|PODXL_CHICK
Podocalyxin
Search

PODXL

0.88	Podocalyxin like

0.77	GO:0016477	cell migration
0.76	GO:0022407	regulation of cell-cell adhesion
0.58	GO:0007162	negative regulation of cell adhesion
0.52	GO:0033630	positive regulation of cell adhesion mediated by integrin
0.51	GO:0007155	cell adhesion
0.49	GO:0030335	positive regulation of cell migration
0.49	GO:0032534	regulation of microvillus assembly
0.44	GO:0072175	epithelial tube formation
0.42	GO:0032835	glomerulus development
0.41	GO:0061318	renal filtration cell differentiation

0.35

GO:0005515

protein binding

0.57	GO:0016324	apical plasma membrane
0.51	GO:0042995	cell projection
0.49	GO:0031252	cell leading edge
0.46	GO:0070062	extracellular exosome
0.43	GO:0005815	microtubule organizing center
0.43	GO:0045121	membrane raft
0.43	GO:0005730	nucleolus
0.42	GO:0036057	slit diaphragm
0.37	GO:0005737	cytoplasm
0.35	GO:0044297	cell body

sp|O73590|ZFHX4_CHICK
Zinc finger homeobox protein 4
Search

ZFHX4

0.87	LOW QUALITY PROTEIN: zinc finger homeobox protein 4

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0045595	regulation of cell differentiation
0.34	GO:1904059	regulation of locomotor rhythm
0.34	GO:0048513	animal organ development
0.34	GO:0007050	cell cycle arrest
0.34	GO:0071559	response to transforming growth factor beta
0.33	GO:0007623	circadian rhythm

0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.34	GO:0001047	core promoter binding
0.33	GO:0001012	RNA polymerase II regulatory region DNA binding
0.33	GO:0003690	double-stranded DNA binding
0.33	GO:0019899	enzyme binding

0.60	GO:0005634	nucleus
0.33	GO:0005667	transcription factor complex
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0005739	mitochondrion
0.32	GO:0044446	intracellular organelle part

sp|O73592|MIXL1_CHICK
Homeobox protein MIXL1
Search

0.78	Homeobox protein SEBOX

0.54	GO:0009790	embryo development
0.53	GO:0007492	endoderm development
0.52	GO:2001141	regulation of RNA biosynthetic process
0.52	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0072359	circulatory system development
0.52	GO:0010468	regulation of gene expression
0.51	GO:0048513	animal organ development
0.50	GO:0035295	tube development
0.50	GO:2000382	positive regulation of mesoderm development
0.50	GO:0030154	cell differentiation

0.58	GO:0043565	sequence-specific DNA binding
0.52	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.51	GO:0035326	enhancer binding
0.50	GO:0001103	RNA polymerase II repressing transcription factor binding
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.47	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0003690	double-stranded DNA binding
0.45	GO:0042803	protein homodimerization activity
0.42	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding

0.61	GO:0005634	nucleus
0.44	GO:0000785	chromatin
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0005667	transcription factor complex
0.30	GO:0031224	intrinsic component of membrane

sp|O73606|KCNG2_CHICK
Potassium voltage-gated channel subfamily G member 2
Search

KCNG2

0.95	Potassium voltage-gated channel modifier subfamily G member 2

0.76	GO:0051260	protein homooligomerization
0.76	GO:0034765	regulation of ion transmembrane transport
0.72	GO:0071805	potassium ion transmembrane transport
0.36	GO:0043266	regulation of potassium ion transport
0.36	GO:0022898	regulation of transmembrane transporter activity
0.34	GO:0050796	regulation of insulin secretion
0.34	GO:0008016	regulation of heart contraction

0.77

GO:0005249

voltage-gated potassium channel activity

0.77	GO:0008076	voltage-gated potassium channel complex
0.36	GO:0070062	extracellular exosome

sp|O73612|EFNB1_CHICK
Ephrin-B1
Search

0.73	GO:0048013	ephrin receptor signaling pathway
0.58	GO:0031295	T cell costimulation
0.56	GO:0001667	ameboidal-type cell migration
0.55	GO:0048699	generation of neurons
0.55	GO:0008284	positive regulation of cell proliferation
0.54	GO:0009653	anatomical structure morphogenesis
0.54	GO:0009888	tissue development
0.53	GO:0048513	animal organ development
0.52	GO:0120036	plasma membrane bounded cell projection organization
0.51	GO:0048468	cell development

0.75	GO:0046875	ephrin receptor binding
0.34	GO:0016301	kinase activity

0.50	GO:0045121	membrane raft
0.45	GO:0005886	plasma membrane
0.42	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0045202	synapse
0.30	GO:0016021	integral component of membrane

tr|O73664|O73664_CHICK
MSSP-1
Search

RBMS1

0.95	RNA binding motif single stranded interacting protein 1

0.36	GO:0006260	DNA replication
0.33	GO:0006396	RNA processing

0.59	GO:0003723	RNA binding
0.34	GO:0003677	DNA binding
0.33	GO:0005515	protein binding

0.46	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.30	GO:0044425	membrane part

sp|O73691|EGR1_CHICK
Early growth response protein 1 (Fragment)
Search

ZENK

0.46	Zinc finger protein (Fragment)

0.51

GO:0003676

nucleic acid binding

sp|O73700|CAC1D_CHICK
Voltage-dependent L-type calcium channel subunit alpha-1D
Search

CACNA1D

0.73	Voltage-dependent L-type calcium channel subunit alpha

0.77	GO:0034765	regulation of ion transmembrane transport
0.77	GO:0070588	calcium ion transmembrane transport
0.57	GO:0086046	membrane depolarization during SA node cell action potential
0.55	GO:0086002	cardiac muscle cell action potential involved in contraction
0.55	GO:0086091	regulation of heart rate by cardiac conduction
0.53	GO:0007605	sensory perception of sound
0.53	GO:0051928	positive regulation of calcium ion transport
0.53	GO:0070509	calcium ion import
0.52	GO:0043266	regulation of potassium ion transport
0.51	GO:0022898	regulation of transmembrane transporter activity

0.82	GO:0005245	voltage-gated calcium channel activity
0.55	GO:0051393	alpha-actinin binding
0.54	GO:0030506	ankyrin binding
0.35	GO:0046872	metal ion binding
0.33	GO:0030165	PDZ domain binding

0.81	GO:0005891	voltage-gated calcium channel complex
0.55	GO:0030315	T-tubule
0.52	GO:0030018	Z disc
0.40	GO:0097470	ribbon synapse
0.39	GO:0009925	basal plasma membrane
0.33	GO:0005887	integral component of plasma membrane
0.33	GO:0032590	dendrite membrane
0.33	GO:0016324	apical plasma membrane
0.33	GO:0043025	neuronal cell body
0.32	GO:0005634	nucleus

sp|O73705|CAC1A_CHICK
Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Fragment)
Search

0.79	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Fragment)

0.76	GO:0070588	calcium ion transmembrane transport
0.76	GO:0034765	regulation of ion transmembrane transport
0.52	GO:0051899	membrane depolarization
0.51	GO:0021750	vestibular nucleus development
0.50	GO:0050883	musculoskeletal movement, spinal reflex action
0.50	GO:0021679	cerebellar molecular layer development
0.50	GO:0030644	cellular chloride ion homeostasis
0.50	GO:0021590	cerebellum maturation
0.50	GO:0014056	regulation of acetylcholine secretion, neurotransmission
0.50	GO:0014051	gamma-aminobutyric acid secretion

0.81	GO:0005245	voltage-gated calcium channel activity
0.43	GO:0005509	calcium ion binding
0.37	GO:0019905	syntaxin binding
0.34	GO:0008022	protein C-terminus binding
0.34	GO:0005516	calmodulin binding

0.80	GO:0005891	voltage-gated calcium channel complex
0.47	GO:0043025	neuronal cell body
0.46	GO:0030425	dendrite
0.45	GO:0098793	presynapse
0.34	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.33	GO:0043234	protein complex

sp|O73706|CAC1B_CHICK
Voltage-dependent N-type calcium channel subunit alpha-1B (Fragment)
Search

0.71	Voltage-dependent N-type calcium channel subunit alpha-1B (Fragment)

0.77	GO:0034765	regulation of ion transmembrane transport
0.76	GO:0070588	calcium ion transmembrane transport
0.52	GO:0048265	response to pain
0.50	GO:0007269	neurotransmitter secretion
0.50	GO:0007626	locomotory behavior
0.49	GO:0051899	membrane depolarization
0.47	GO:0008016	regulation of heart contraction
0.47	GO:0008217	regulation of blood pressure
0.47	GO:0051924	regulation of calcium ion transport
0.46	GO:0001508	action potential

0.81	GO:0005245	voltage-gated calcium channel activity
0.53	GO:0005509	calcium ion binding
0.48	GO:0008022	protein C-terminus binding
0.35	GO:0019905	syntaxin binding
0.34	GO:0051721	protein phosphatase 2A binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005516	calmodulin binding

0.80	GO:0005891	voltage-gated calcium channel complex
0.50	GO:0043025	neuronal cell body
0.50	GO:0030425	dendrite
0.49	GO:0098793	presynapse
0.36	GO:0044306	neuron projection terminus
0.33	GO:0009986	cell surface
0.33	GO:0005634	nucleus
0.33	GO:0043234	protein complex
0.32	GO:0005737	cytoplasm

sp|O73707|CAC1C_CHICK
Voltage-dependent L-type calcium channel subunit alpha-1C (Fragment)
Search

CACNA1C

0.75	Calcium voltage-gated channel subunit alpha1 C

0.76	GO:0034765	regulation of ion transmembrane transport
0.76	GO:0070588	calcium ion transmembrane transport
0.51	GO:0086010	membrane depolarization during action potential
0.49	GO:0061337	cardiac conduction
0.49	GO:0098911	regulation of ventricular cardiac muscle cell action potential
0.49	GO:0086002	cardiac muscle cell action potential involved in contraction
0.48	GO:0035115	embryonic forelimb morphogenesis
0.48	GO:0002027	regulation of heart rate
0.47	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.46	GO:0043010	camera-type eye development

0.81	GO:0005245	voltage-gated calcium channel activity
0.48	GO:0051393	alpha-actinin binding
0.45	GO:0005516	calmodulin binding
0.38	GO:1905030	voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential
0.35	GO:0051721	protein phosphatase 2A binding
0.34	GO:0044325	ion channel binding
0.34	GO:0030506	ankyrin binding
0.34	GO:0031369	translation initiation factor binding
0.34	GO:0046872	metal ion binding
0.34	GO:0019904	protein domain specific binding

0.80	GO:0005891	voltage-gated calcium channel complex
0.50	GO:0030315	T-tubule
0.47	GO:0014069	postsynaptic density
0.38	GO:0030018	Z disc
0.38	GO:0002095	caveolar macromolecular signaling complex
0.36	GO:0043198	dendritic shaft
0.36	GO:0043025	neuronal cell body
0.35	GO:0045211	postsynaptic membrane
0.35	GO:0042734	presynaptic membrane
0.33	GO:0005634	nucleus

sp|O73718|TBX3_CHICK
T-box transcription factor TBX3 (Fragment)
Search

TBX3

0.80	T-box transcription factor TBX3

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:0046884	follicle-stimulating hormone secretion
0.46	GO:0032275	luteinizing hormone secretion
0.45	GO:0030540	female genitalia development
0.45	GO:0045662	negative regulation of myoblast differentiation
0.45	GO:0035115	embryonic forelimb morphogenesis
0.45	GO:0030539	male genitalia development

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.41	GO:0001102	RNA polymerase II activating transcription factor binding
0.39	GO:0001067	regulatory region nucleic acid binding
0.38	GO:0051087	chaperone binding

0.61	GO:0005634	nucleus
0.35	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|O73737|MAP6_CHICK
Microtubule-associated protein 6 homolog
Search

MAP6

0.95	Microtubule-associated protein 6

0.76	GO:0000226	microtubule cytoskeleton organization
0.51	GO:0032418	lysosome localization
0.50	GO:0048813	dendrite morphogenesis
0.34	GO:0019896	axonal transport of mitochondrion
0.34	GO:0050772	positive regulation of axonogenesis
0.33	GO:0070507	regulation of microtubule cytoskeleton organization

0.79	GO:0005516	calmodulin binding
0.74	GO:0008017	microtubule binding

0.73	GO:0005874	microtubule
0.45	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0030425	dendrite
0.35	GO:0030424	axon
0.34	GO:0030658	transport vesicle membrane
0.34	GO:0005794	Golgi apparatus
0.34	GO:0120111	neuron projection cytoplasm
0.33	GO:0099503	secretory vesicle

tr|O73739|O73739_CHICK
Endothelin receptor type A
Search

EDNRA

0.97	Endothelin receptor type A

0.86	GO:0086100	endothelin receptor signaling pathway
0.85	GO:0048484	enteric nervous system development
0.85	GO:0042310	vasoconstriction
0.83	GO:0008217	regulation of blood pressure
0.59	GO:0014820	tonic smooth muscle contraction
0.57	GO:0014032	neural crest cell development
0.57	GO:0001569	branching involved in blood vessel morphogenesis
0.57	GO:0007585	respiratory gaseous exchange
0.56	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.54	GO:0001666	response to hypoxia

0.86	GO:0004962	endothelin receptor activity
0.39	GO:0017046	peptide hormone binding
0.34	GO:0004435	phosphatidylinositol phospholipase C activity
0.34	GO:0004713	protein tyrosine kinase activity
0.34	GO:0005515	protein binding
0.33	GO:0003924	GTPase activity
0.33	GO:0005525	GTP binding
0.32	GO:0003735	structural constituent of ribosome

0.37	GO:0005886	plasma membrane
0.34	GO:0098857	membrane microdomain
0.34	GO:0031965	nuclear membrane
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.34	EC:3.1.4.11	GO:0004435
0.34	KEGG:R03435	GO:0004435

sp|O73755|GREM1_CHICK
Gremlin-1
Search

GREM1

0.97	Gremlin 1, DAN family BMP antagonist

0.74	GO:0010469	regulation of receptor activity
0.67	GO:0090291	negative regulation of osteoclast proliferation
0.66	GO:0048263	determination of dorsal identity
0.66	GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis
0.66	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation
0.66	GO:0003257	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
0.66	GO:1900155	negative regulation of bone trabecula formation
0.66	GO:0060676	ureteric bud formation
0.65	GO:1900158	negative regulation of bone mineralization involved in bone maturation
0.65	GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis

0.77	GO:0005125	cytokine activity
0.66	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.66	GO:0043184	vascular endothelial growth factor receptor 2 binding
0.65	GO:0036122	BMP binding
0.56	GO:0042803	protein homodimerization activity
0.40	GO:0008201	heparin binding
0.40	GO:0016015	morphogen activity
0.36	GO:0043395	heparan sulfate proteoglycan binding

0.72	GO:0005615	extracellular space
0.56	GO:0009986	cell surface
0.30	GO:0016020	membrane

sp|O73770|DGCR6_CHICK
Protein DGCR6
Search

DGCR6

0.97	DiGeorge syndrome critical region gene 6

0.53	GO:0032501	multicellular organismal process
0.49	GO:0007155	cell adhesion
0.49	GO:0009653	anatomical structure morphogenesis
0.48	GO:0009593	detection of chemical stimulus
0.46	GO:0007186	G-protein coupled receptor signaling pathway

0.48	GO:0004984	olfactory receptor activity
0.46	GO:0004930	G-protein coupled receptor activity
0.45	GO:0005515	protein binding

0.51	GO:0005578	proteinaceous extracellular matrix
0.50	GO:0005634	nucleus
0.40	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|O73775|FBLN1_CHICK
Fibulin-1
Search

FBLN1

0.83

Fibulin-1

0.81	GO:0010952	positive regulation of peptidase activity
0.80	GO:0030198	extracellular matrix organization
0.55	GO:0072378	blood coagulation, fibrin clot formation
0.55	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading
0.54	GO:2000647	negative regulation of stem cell proliferation
0.53	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.52	GO:2000146	negative regulation of cell motility
0.42	GO:1904188	negative regulation of transformation of host cell by virus
0.41	GO:0007566	embryo implantation
0.41	GO:1904237	positive regulation of substrate-dependent cell migration, cell attachment to substrate

0.83	GO:0016504	peptidase activator activity
0.70	GO:0005509	calcium ion binding
0.57	GO:0070051	fibrinogen binding
0.55	GO:0001968	fibronectin binding
0.52	GO:0008022	protein C-terminus binding
0.52	GO:0005201	extracellular matrix structural constituent
0.48	GO:0042802	identical protein binding
0.41	GO:0005178	integrin binding

0.65	GO:0005576	extracellular region
0.42	GO:0043234	protein complex
0.36	GO:0031982	vesicle
0.32	GO:0005622	intracellular

sp|O73777|IF4G2_CHICK
Eukaryotic translation initiation factor 4 gamma 2 (Fragment)
Search

EIF4G2

0.53	Eukaryotic translation initiation factor 4 gamma 2

0.60	GO:0006413	translational initiation
0.43	GO:0007498	mesoderm development
0.40	GO:0006417	regulation of translation
0.39	GO:0030307	positive regulation of cell growth
0.38	GO:0060999	positive regulation of dendritic spine development
0.37	GO:0050772	positive regulation of axonogenesis
0.37	GO:0030516	regulation of axon extension
0.37	GO:0048639	positive regulation of developmental growth
0.37	GO:0007507	heart development
0.36	GO:0034250	positive regulation of cellular amide metabolic process

0.61	GO:0003743	translation initiation factor activity
0.37	GO:0045296	cadherin binding

0.46	GO:0005829	cytosol
0.41	GO:0016281	eukaryotic translation initiation factor 4F complex
0.37	GO:0005913	cell-cell adherens junction
0.37	GO:0030424	axon
0.30	GO:0016021	integral component of membrane

sp|O73790|SPB10_CHICK
Heterochromatin-associated protein MENT
Search

SERPINB10

0.97	Heterochromatin-associated protein MENT

0.53	GO:0010951	negative regulation of endopeptidase activity
0.38	GO:0043066	negative regulation of apoptotic process
0.37	GO:0043362	nucleate erythrocyte maturation
0.35	GO:0030261	chromosome condensation
0.35	GO:0006508	proteolysis
0.35	GO:0016569	covalent chromatin modification
0.34	GO:0042270	protection from natural killer cell mediated cytotoxicity
0.34	GO:0002448	mast cell mediated immunity
0.34	GO:0033668	negative regulation by symbiont of host apoptotic process
0.34	GO:0071391	cellular response to estrogen stimulus

0.54	GO:0004867	serine-type endopeptidase inhibitor activity
0.36	GO:0031490	chromatin DNA binding
0.35	GO:0008233	peptidase activity
0.34	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.33	GO:0002020	protease binding
0.33	GO:0004674	protein serine/threonine kinase activity

0.73	GO:0005615	extracellular space
0.35	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.35	GO:0000785	chromatin
0.33	GO:0005737	cytoplasm
0.32	GO:0012505	endomembrane system
0.31	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0008233

tr|O73816|O73816_CHICK
High mobility group protein I-C
Search

HMGA2

0.96	High mobility group protein HMGI-C

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0090402	oncogene-induced cell senescence
0.52	GO:0035986	senescence-associated heterochromatin focus assembly
0.51	GO:2000774	positive regulation of cellular senescence
0.49	GO:0031052	chromosome breakage
0.49	GO:0035978	histone H2A-S139 phosphorylation
0.49	GO:0003131	mesodermal-endodermal cell signaling
0.48	GO:2000685	positive regulation of cellular response to X-ray

0.55	GO:0003677	DNA binding
0.49	GO:0035501	MH1 domain binding
0.48	GO:0035500	MH2 domain binding
0.48	GO:0051575	5'-deoxyribose-5-phosphate lyase activity
0.47	GO:0070742	C2H2 zinc finger domain binding
0.46	GO:0004677	DNA-dependent protein kinase activity
0.46	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity
0.45	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0031491	nucleosome binding

0.72	GO:0000785	chromatin
0.61	GO:0005634	nucleus
0.47	GO:0071141	SMAD protein complex
0.42	GO:0032993	protein-DNA complex
0.41	GO:0070013	intracellular organelle lumen
0.35	GO:0005667	transcription factor complex
0.33	GO:0005925	focal adhesion
0.33	GO:0005829	cytosol

0.46

GO:0004677

tr|O73883|O73883_CHICK
IL-2
Search

0.88	Interleukin

0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.63	GO:0036037	CD8-positive, alpha-beta T cell activation
0.62	GO:0050671	positive regulation of lymphocyte proliferation
0.54	GO:0010628	positive regulation of gene expression
0.42	GO:0035710	CD4-positive, alpha-beta T cell activation

0.80	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding

0.73	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

sp|O73884|PHOP1_CHICK
Phosphoethanolamine/phosphocholine phosphatase
Search

PHOSPHO1

0.97	Phosphoethanolamine/phosphocholine phosphatase

0.68	GO:0016311	dephosphorylation
0.61	GO:0035630	bone mineralization involved in bone maturation
0.55	GO:0001958	endochondral ossification
0.40	GO:0030500	regulation of bone mineralization
0.35	GO:0006656	phosphatidylcholine biosynthetic process
0.35	GO:0006646	phosphatidylethanolamine biosynthetic process

0.69	GO:0016791	phosphatase activity
0.42	GO:0016462	pyrophosphatase activity
0.34	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.56	GO:0065010	extracellular membrane-bounded organelle
0.50	GO:0005578	proteinaceous extracellular matrix
0.34	GO:0005829	cytosol

0.69

EC:3.1.3 EC:3.1.3.41

GO:0016791

sp|O73885|HSP7C_CHICK
Heat shock cognate 71 kDa protein
Search

HSPA8

0.75	Heat shock cognate protein isoform A

0.56	GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy
0.55	GO:0061738	late endosomal microautophagy
0.54	GO:0072318	clathrin coat disassembly
0.54	GO:0044829	positive regulation by host of viral genome replication
0.53	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.51	GO:0051085	chaperone cofactor-dependent protein refolding
0.50	GO:1902904	negative regulation of supramolecular fiber organization
0.50	GO:0031647	regulation of protein stability
0.49	GO:0042026	protein refolding
0.48	GO:0045892	negative regulation of transcription, DNA-templated

0.56	GO:0055131	C3HC4-type RING finger domain binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0001786	phosphatidylserine binding
0.51	GO:0045296	cadherin binding
0.50	GO:0001664	G-protein coupled receptor binding
0.50	GO:0031072	heat shock protein binding
0.50	GO:0031625	ubiquitin protein ligase binding

0.53	GO:0000974	Prp19 complex
0.51	GO:0070062	extracellular exosome
0.51	GO:0043209	myelin sheath
0.50	GO:0005770	late endosome
0.49	GO:0000151	ubiquitin ligase complex
0.46	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.44	GO:0030529	intracellular ribonucleoprotein complex
0.42	GO:0042470	melanosome
0.38	GO:0043202	lysosomal lumen

sp|O73888|HPGDS_CHICK
Hematopoietic prostaglandin D synthase
Search

HPGDS

0.70	Glutathione-requiring prostaglandin D synthase

0.79	GO:0006692	prostanoid metabolic process
0.76	GO:2000255	negative regulation of male germ cell proliferation
0.47	GO:0046456	icosanoid biosynthetic process
0.46	GO:0006636	unsaturated fatty acid biosynthetic process
0.40	GO:1901685	glutathione derivative metabolic process
0.39	GO:0019369	arachidonic acid metabolic process
0.38	GO:0007626	locomotory behavior
0.36	GO:0044272	sulfur compound biosynthetic process
0.35	GO:0045087	innate immune response
0.35	GO:0007165	signal transduction

0.85	GO:0004667	prostaglandin-D synthase activity
0.69	GO:0042803	protein homodimerization activity
0.64	GO:0005509	calcium ion binding
0.60	GO:0000287	magnesium ion binding
0.52	GO:0004364	glutathione transferase activity
0.40	GO:0005212	structural constituent of eye lens

0.36

GO:0005737

cytoplasm

0.85	EC:5.3.99.2	GO:0004667
0.85	KEGG:R02266	GO:0004667

sp|O73895|TPSN_CHICK
Tapasin
Search

0.85	TAP binding protein like

0.53	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
0.37	GO:0002590	negative regulation of antigen processing and presentation of peptide antigen via MHC class I
0.34	GO:0045579	positive regulation of B cell differentiation
0.34	GO:0045582	positive regulation of T cell differentiation
0.33	GO:0035725	sodium ion transmembrane transport
0.33	GO:0043066	negative regulation of apoptotic process
0.33	GO:0016567	protein ubiquitination
0.32	GO:0007165	signal transduction

0.39	GO:0005509	calcium ion binding
0.36	GO:0032403	protein complex binding
0.34	GO:0015280	ligand-gated sodium channel activity
0.33	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0004888	transmembrane signaling receptor activity
0.32	GO:0008270	zinc ion binding

0.37	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

tr|O73911|O73911_CHICK
K123 protein
Search

0.92	Endonuclease domain-containing 1

0.58

GO:0090305

nucleic acid phosphodiester bond hydrolysis

0.59	GO:0004519	endonuclease activity
0.54	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding

0.30

GO:0031224

intrinsic component of membrane

tr|O73912|O73912_CHICK
C-X-C motif chemokine
Search

CXCL8

0.42	Multifunctional fusion protein (Fragment)

0.84	GO:0042119	neutrophil activation
0.84	GO:0030593	neutrophil chemotaxis
0.78	GO:0006954	inflammatory response
0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.46	GO:0036446	myofibroblast differentiation
0.44	GO:0042127	regulation of cell proliferation
0.44	GO:0048246	macrophage chemotaxis
0.44	GO:0050921	positive regulation of chemotaxis
0.44	GO:0002548	monocyte chemotaxis

0.86	GO:0005153	interleukin-8 receptor binding
0.84	GO:0008009	chemokine activity
0.35	GO:0008083	growth factor activity
0.33	GO:0005355	glucose transmembrane transporter activity

0.73	GO:0005615	extracellular space
0.34	GO:1904724	tertiary granule lumen
0.34	GO:0031093	platelet alpha granule lumen
0.30	GO:0016020	membrane

sp|O73930|PHS_CHICK
Pterin-4-alpha-carbinolamine dehydratase
Search

PCBD1

0.80	Pterin-4-alpha-carbinolamine dehydratase

0.80	GO:0046146	tetrahydrobiopterin metabolic process
0.80	GO:0034312	diol biosynthetic process
0.72	GO:0042559	pteridine-containing compound biosynthetic process
0.65	GO:0009108	coenzyme biosynthetic process
0.55	GO:0051291	protein heterooligomerization
0.54	GO:0051289	protein homotetramerization
0.40	GO:0055114	oxidation-reduction process
0.39	GO:0043496	regulation of protein homodimerization activity
0.38	GO:0006558	L-phenylalanine metabolic process
0.37	GO:0045893	positive regulation of transcription, DNA-templated

0.81	GO:0008124	4-alpha-hydroxytetrahydrobiopterin dehydratase activity
0.54	GO:0004505	phenylalanine 4-monooxygenase activity
0.49	GO:0042802	identical protein binding
0.38	GO:0003713	transcription coactivator activity

0.48	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome

0.81	EC:4.2.1.96	GO:0008124
0.81	KEGG:R04734	GO:0008124

tr|O73933|O73933_CHICK
Id2
Search

ID2

0.97	Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.58	GO:0061031	endodermal digestive tract morphogenesis
0.56	GO:0045578	negative regulation of B cell differentiation
0.56	GO:0045777	positive regulation of blood pressure
0.56	GO:0048557	embryonic digestive tract morphogenesis
0.56	GO:0003166	bundle of His development
0.56	GO:0090398	cellular senescence
0.56	GO:2000178	negative regulation of neural precursor cell proliferation
0.56	GO:0001966	thigmotaxis
0.56	GO:0071158	positive regulation of cell cycle arrest

0.68	GO:0046983	protein dimerization activity
0.54	GO:0044325	ion channel binding
0.47	GO:0003677	DNA binding
0.40	GO:0043425	bHLH transcription factor binding
0.35	GO:1901707	leptomycin B binding
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0019904	protein domain specific binding

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.43	GO:0043234	protein complex
0.34	GO:0000785	chromatin

sp|O93256|K1C19_CHICK
Keratin, type I cytoskeletal 19
Search

KRT19

0.88	Putative nuclear envelope protein lamin intermediate filament superfamily

0.52	GO:0043627	response to estrogen
0.52	GO:0045214	sarcomere organization
0.50	GO:0007219	Notch signaling pathway
0.49	GO:0060706	cell differentiation involved in embryonic placenta development
0.49	GO:0045103	intermediate filament-based process
0.49	GO:0042633	hair cycle
0.46	GO:0030855	epithelial cell differentiation
0.44	GO:0043588	skin development
0.44	GO:0008544	epidermis development
0.43	GO:0007568	aging

0.62	GO:0005198	structural molecule activity
0.44	GO:1990254	keratin filament binding
0.44	GO:0032395	MHC class II receptor activity
0.43	GO:0042289	MHC class II protein binding
0.38	GO:0097110	scaffold protein binding

0.79	GO:0005882	intermediate filament
0.53	GO:0043034	costamere
0.53	GO:1990357	terminal web
0.52	GO:0016327	apicolateral plasma membrane
0.51	GO:0042383	sarcolemma
0.51	GO:0030018	Z disc
0.43	GO:0045178	basal part of cell
0.39	GO:0070062	extracellular exosome
0.38	GO:0016010	dystrophin-associated glycoprotein complex
0.38	GO:0005634	nucleus

sp|O93257|XRCC6_CHICK
X-ray repair cross-complementing protein 5
Search

XRCC6

0.76	X-ray repair cross-complementing protein 5

0.81	GO:0006303	double-strand break repair via nonhomologous end joining
0.79	GO:0000723	telomere maintenance
0.69	GO:0032508	DNA duplex unwinding
0.48	GO:0071480	cellular response to gamma radiation
0.46	GO:0051290	protein heterotetramerization
0.45	GO:0048660	regulation of smooth muscle cell proliferation
0.44	GO:0002218	activation of innate immune response
0.43	GO:0045860	positive regulation of protein kinase activity
0.43	GO:0071475	cellular hyperosmotic salinity response
0.43	GO:0071481	cellular response to X-ray

0.82	GO:0042162	telomeric DNA binding
0.73	GO:0003684	damaged DNA binding
0.71	GO:0004003	ATP-dependent DNA helicase activity
0.49	GO:0051575	5'-deoxyribose-5-phosphate lyase activity
0.44	GO:0008022	protein C-terminus binding
0.44	GO:0030332	cyclin binding
0.42	GO:0044212	transcription regulatory region DNA binding
0.41	GO:0003690	double-stranded DNA binding
0.39	GO:0044877	macromolecular complex binding
0.37	GO:0003723	RNA binding

0.84	GO:0043564	Ku70:Ku80 complex
0.48	GO:0070419	nonhomologous end joining complex
0.43	GO:0000784	nuclear chromosome, telomeric region
0.43	GO:0005654	nucleoplasm
0.42	GO:0005667	transcription factor complex
0.42	GO:0005730	nucleolus
0.41	GO:0032993	protein-DNA complex
0.38	GO:1904813	ficolin-1-rich granule lumen
0.37	GO:0034774	secretory granule lumen
0.35	GO:0005829	cytosol

sp|O93277|WDR1_CHICK
WD repeat-containing protein 1
Search

WDR1

0.96	WD repeat-containing protein 1

0.84	GO:0030043	actin filament fragmentation
0.83	GO:0042247	establishment of planar polarity of follicular epithelium
0.81	GO:0045199	maintenance of epithelial cell apical/basal polarity
0.80	GO:0030836	positive regulation of actin filament depolymerization
0.79	GO:0045214	sarcomere organization
0.79	GO:0030220	platelet formation
0.78	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization
0.78	GO:0043297	apical junction assembly
0.77	GO:0002446	neutrophil mediated immunity
0.76	GO:1990266	neutrophil migration

0.59	GO:0051015	actin filament binding
0.34	GO:0022857	transmembrane transporter activity
0.30	GO:0003824	catalytic activity

0.73	GO:0043209	myelin sheath
0.70	GO:0005911	cell-cell junction
0.66	GO:0042643	actomyosin, actin portion
0.59	GO:0030864	cortical actin cytoskeleton
0.53	GO:0005886	plasma membrane
0.48	GO:0002102	podosome
0.42	GO:0042995	cell projection
0.41	GO:0070062	extracellular exosome
0.38	GO:0005634	nucleus
0.36	GO:0005829	cytosol

tr|O93288|O93288_CHICK
T-Box protein 4
Search

TBX4

0.97	T-box transcription factor TBX4

0.65	GO:0035108	limb morphogenesis
0.64	GO:0035113	embryonic appendage morphogenesis
0.60	GO:0030324	lung development
0.58	GO:0072359	circulatory system development
0.58	GO:0002009	morphogenesis of an epithelium
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0009887	animal organ morphogenesis
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0008134	transcription factor binding
0.38	GO:0030274	LIM domain binding
0.35	GO:0097110	scaffold protein binding
0.34	GO:0051087	chaperone binding

0.61	GO:0005634	nucleus
0.44	GO:0032993	protein-DNA complex
0.37	GO:0097517	contractile actin filament bundle
0.37	GO:0042641	actomyosin
0.37	GO:0005884	actin filament
0.37	GO:0005737	cytoplasm
0.33	GO:0043233	organelle lumen

sp|O93295|ENTP8_CHICK
Ectonucleoside triphosphate diphosphohydrolase 8
Search

ENTPD8

0.97	Ectonucleoside triphosphate diphosphohydrolase 8

0.43	GO:0009132	nucleoside diphosphate metabolic process
0.40	GO:0009143	nucleoside triphosphate catabolic process
0.39	GO:0009124	nucleoside monophosphate biosynthetic process
0.36	GO:0071405	cellular response to methanol
0.35	GO:0045471	response to ethanol
0.35	GO:0046688	response to copper ion
0.34	GO:0030168	platelet activation
0.34	GO:0005975	carbohydrate metabolic process
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0055114	oxidation-reduction process

0.51	GO:0016787	hydrolase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046872	metal ion binding

0.36	GO:0005886	plasma membrane
0.34	GO:0005605	basal lamina
0.30	GO:0031224	intrinsic component of membrane

0.51

GO:0016787

sp|O93307|SIX6_CHICK
Homeobox protein SIX6
Search

SIX6

0.93	Sine oculis homeobox 6

0.79	GO:0001654	eye development
0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.59	GO:0007420	brain development
0.54	GO:0006366	transcription by RNA polymerase II
0.53	GO:0045893	positive regulation of transcription, DNA-templated
0.52	GO:0097402	neuroblast migration
0.51	GO:1990086	lens fiber cell apoptotic process
0.51	GO:0009946	proximal/distal axis specification
0.50	GO:0061074	regulation of neural retina development
0.50	GO:0002070	epithelial cell maturation

0.72	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.55	GO:0003677	DNA binding
0.50	GO:0001222	transcription corepressor binding
0.48	GO:0042826	histone deacetylase binding
0.46	GO:0003713	transcription coactivator activity
0.45	GO:0001067	regulatory region nucleic acid binding
0.37	GO:0005102	receptor binding
0.34	GO:0004722	protein serine/threonine phosphatase activity
0.33	GO:0030145	manganese ion binding
0.33	GO:0000287	magnesium ion binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|O93319|CAD11_CHICK
Cadherin-11
Search

CDH11

0.82	Osteoblast cadherin

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.55	GO:0021957	corticospinal tract morphogenesis
0.42	GO:0048840	otolith development
0.42	GO:0031290	retinal ganglion cell axon guidance
0.41	GO:0060041	retina development in camera-type eye
0.40	GO:0035249	synaptic transmission, glutamatergic
0.39	GO:0009409	response to cold
0.36	GO:0034332	adherens junction organization
0.35	GO:0030199	collagen fibril organization
0.34	GO:0001503	ossification

0.70	GO:0005509	calcium ion binding
0.37	GO:0042802	identical protein binding
0.35	GO:0008013	beta-catenin binding
0.33	GO:0046983	protein dimerization activity

0.56	GO:0005886	plasma membrane
0.40	GO:0043083	synaptic cleft
0.39	GO:0043679	axon terminus
0.38	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.34	GO:0005911	cell-cell junction
0.30	GO:0016021	integral component of membrane

sp|O93327|H2AY_CHICK
Core histone macro-H2A.1
Search

H2AFY

0.96	Core histone macro-H2A

0.72	GO:0006334	nucleosome assembly
0.67	GO:0016569	covalent chromatin modification
0.59	GO:1904815	negative regulation of protein localization to chromosome, telomeric region
0.58	GO:0033128	negative regulation of histone phosphorylation
0.58	GO:1901837	negative regulation of transcription of nucleolar large rRNA by RNA polymerase I
0.58	GO:0051572	negative regulation of histone H3-K4 methylation
0.58	GO:0034184	positive regulation of maintenance of mitotic sister chromatid cohesion
0.58	GO:0061086	negative regulation of histone H3-K27 methylation
0.57	GO:0071169	establishment of protein localization to chromatin
0.57	GO:0045618	positive regulation of keratinocyte differentiation

0.76	GO:0031490	chromatin DNA binding
0.74	GO:0046982	protein heterodimerization activity
0.57	GO:0010385	double-stranded methylated DNA binding
0.56	GO:0000182	rDNA binding
0.56	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.54	GO:0030291	protein serine/threonine kinase inhibitor activity
0.54	GO:0031491	nucleosome binding
0.52	GO:0019901	protein kinase binding

0.74	GO:0000786	nucleosome
0.68	GO:0000790	nuclear chromatin
0.55	GO:0001740	Barr body
0.55	GO:0005721	pericentric heterochromatin
0.55	GO:0035098	ESC/E(Z) complex
0.51	GO:0000793	condensed chromosome
0.49	GO:0005730	nucleolus
0.36	GO:0000784	nuclear chromosome, telomeric region
0.36	GO:0070062	extracellular exosome
0.34	GO:0005813	centrosome

sp|O93344|AL1A2_CHICK
Retinal dehydrogenase 2
Search

ALDH1A2

0.89	Retinal dehydrogenase 2

0.53	GO:0055114	oxidation-reduction process
0.48	GO:0035799	ureter maturation
0.48	GO:0042904	9-cis-retinoic acid biosynthetic process
0.47	GO:0042574	retinal metabolic process
0.46	GO:0035115	embryonic forelimb morphogenesis
0.46	GO:0071300	cellular response to retinoic acid
0.46	GO:0009954	proximal/distal pattern formation
0.46	GO:0048384	retinoic acid receptor signaling pathway
0.46	GO:0048566	embryonic digestive tract development
0.46	GO:0031076	embryonic camera-type eye development

0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.42	GO:0016918	retinal binding
0.37	GO:0004745	retinol dehydrogenase activity

0.40	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005829	cytosol

0.69

GO:0016620

tr|O93345|O93345_CHICK
Lymphiod enhancer binding factor 1
Search

LEF1

0.93	Lymphoid enhancer-binding factor 1

0.76	GO:0016055	Wnt signaling pathway
0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.49	GO:0021872	forebrain generation of neurons
0.49	GO:0061152	trachea submucosa development
0.49	GO:0001756	somitogenesis
0.49	GO:0021761	limbic system development
0.49	GO:0021943	formation of radial glial scaffolds
0.48	GO:0048762	mesenchymal cell differentiation
0.48	GO:0048341	paraxial mesoderm formation
0.48	GO:0060019	radial glial cell differentiation

0.82	GO:0008013	beta-catenin binding
0.54	GO:0003677	DNA binding
0.47	GO:0070016	armadillo repeat domain binding
0.47	GO:0045295	gamma-catenin binding
0.46	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.46	GO:0030331	estrogen receptor binding
0.43	GO:0001067	regulatory region nucleic acid binding
0.43	GO:0070742	C2H2 zinc finger domain binding
0.43	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.43	GO:0030284	estrogen receptor activity

0.60	GO:0005634	nucleus
0.43	GO:0005667	transcription factor complex
0.39	GO:0032993	protein-DNA complex
0.36	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm

sp|O93353|HXA3_CHICK
Homeobox protein Hox-A3
Search

0.91	Transcription factor HoxB3

0.69	GO:0007275	multicellular organism development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0061448	connective tissue development
0.49	GO:0001974	blood vessel remodeling
0.46	GO:0008284	positive regulation of cell proliferation
0.45	GO:0009653	anatomical structure morphogenesis
0.44	GO:0002376	immune system process
0.39	GO:0007219	Notch signaling pathway

0.64	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.49	GO:0071837	HMG box domain binding
0.38	GO:0001012	RNA polymerase II regulatory region DNA binding
0.37	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.43	GO:0043233	organelle lumen
0.40	GO:0044446	intracellular organelle part
0.40	GO:0016235	aggresome

sp|O93366|TLX1_CHICK
T-cell leukemia homeobox protein 1
Search

0.96	T-cell leukemia homeobox protein 1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0002087	regulation of respiratory gaseous exchange by neurological system process
0.48	GO:0007585	respiratory gaseous exchange
0.48	GO:0048665	neuron fate specification
0.47	GO:0001764	neuron migration
0.47	GO:0045665	negative regulation of neuron differentiation
0.46	GO:0006366	transcription by RNA polymerase II
0.46	GO:0007417	central nervous system development

0.64	GO:0043565	sequence-specific DNA binding
0.48	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003690	double-stranded DNA binding
0.35	GO:0005515	protein binding
0.32	GO:0005198	structural molecule activity

0.61	GO:0005634	nucleus
0.42	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part
0.34	GO:0045111	intermediate filament cytoskeleton
0.33	GO:0099512	supramolecular fiber

sp|O93367|TLX3_CHICK
T-cell leukemia homeobox protein 3
Search

TLX3

0.96	T-cell leukemia homeobox protein 3

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0002087	regulation of respiratory gaseous exchange by neurological system process
0.53	GO:0007585	respiratory gaseous exchange
0.53	GO:0048665	neuron fate specification
0.52	GO:0045665	negative regulation of neuron differentiation
0.52	GO:0001764	neuron migration
0.50	GO:0007417	central nervous system development
0.43	GO:0048839	inner ear development

0.63	GO:0043565	sequence-specific DNA binding
0.44	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.42	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.42	GO:0001012	RNA polymerase II regulatory region DNA binding
0.40	GO:0003690	double-stranded DNA binding
0.36	GO:0005515	protein binding
0.33	GO:0005198	structural molecule activity

0.60	GO:0005634	nucleus
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.34	GO:0045111	intermediate filament cytoskeleton
0.34	GO:0099512	supramolecular fiber
0.32	GO:0005737	cytoplasm

sp|O93385|PITX2_CHICK
Pituitary homeobox 2
Search

PITX2

0.83	Pituitary homeobox 2

0.69	GO:0007275	multicellular organism development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:2000288	positive regulation of myoblast proliferation
0.54	GO:0003228	atrial cardiac muscle tissue development
0.53	GO:0060322	head development
0.53	GO:0048857	neural nucleus development
0.53	GO:0051145	smooth muscle cell differentiation
0.53	GO:0002009	morphogenesis of an epithelium

0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0001105	RNA polymerase II transcription coactivator activity
0.54	GO:0001102	RNA polymerase II activating transcription factor binding
0.51	GO:0031490	chromatin DNA binding
0.49	GO:0044212	transcription regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.38	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.37	GO:0051219	phosphoprotein binding
0.36	GO:0042803	protein homodimerization activity

0.61	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.38	GO:0005737	cytoplasm
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part

sp|O93388|STMN3_CHICK
Stathmin-3
Search

STMN3

0.85

Stathmin

0.84	GO:0031110	regulation of microtubule polymerization or depolymerization
0.75	GO:0031122	cytoplasmic microtubule organization
0.72	GO:0031175	neuron projection development
0.57	GO:0035021	negative regulation of Rac protein signal transduction
0.51	GO:0007019	microtubule depolymerization
0.50	GO:0043087	regulation of GTPase activity
0.49	GO:1990090	cellular response to nerve growth factor stimulus
0.47	GO:1901881	positive regulation of protein depolymerization
0.47	GO:0010977	negative regulation of neuron projection development
0.47	GO:0010976	positive regulation of neuron projection development

0.68	GO:0015631	tubulin binding
0.50	GO:0019904	protein domain specific binding
0.47	GO:0048306	calcium-dependent protein binding
0.35	GO:0008022	protein C-terminus binding

0.52	GO:0043005	neuron projection
0.49	GO:0030427	site of polarized growth
0.47	GO:0120038	plasma membrane bounded cell projection part
0.47	GO:0005737	cytoplasm
0.47	GO:0030027	lamellipodium
0.46	GO:0043025	neuronal cell body
0.39	GO:0012505	endomembrane system
0.36	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

tr|O93393|O93393_CHICK
Calcium-activated potassium channel beta subunit
Search

KCNMB1

0.97	Calcium-activated potassium channel beta subunit

0.73	GO:0071805	potassium ion transmembrane transport
0.50	GO:0005513	detection of calcium ion
0.45	GO:0007268	chemical synaptic transmission
0.42	GO:0065009	regulation of molecular function
0.40	GO:1903413	cellular response to bile acid
0.39	GO:0071361	cellular response to ethanol
0.38	GO:0097755	positive regulation of blood vessel diameter
0.38	GO:1901381	positive regulation of potassium ion transmembrane transport
0.38	GO:0071456	cellular response to hypoxia
0.37	GO:0007568	aging

0.84	GO:0015269	calcium-activated potassium channel activity
0.49	GO:0015459	potassium channel regulator activity
0.33	GO:0005515	protein binding

0.45

GO:0008076

voltage-gated potassium channel complex

tr|O93417|O93417_CHICK
Caspase-3
Search

CASP3

0.95	Caspase 3, apoptosis-related cysteine peptidase a

0.61	GO:0006508	proteolysis
0.57	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress
0.57	GO:0072733	response to staurosporine
0.57	GO:0097194	execution phase of apoptosis
0.57	GO:0030216	keratinocyte differentiation
0.56	GO:0030218	erythrocyte differentiation
0.56	GO:0034349	glial cell apoptotic process
0.55	GO:0046007	negative regulation of activated T cell proliferation
0.55	GO:0030889	negative regulation of B cell proliferation
0.55	GO:0071312	cellular response to alkaloid

0.75	GO:0004197	cysteine-type endopeptidase activity
0.53	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.47	GO:0004190	aspartic-type endopeptidase activity
0.39	GO:0016005	phospholipase A2 activator activity
0.38	GO:0005123	death receptor binding
0.37	GO:0002020	protease binding
0.36	GO:0032403	protein complex binding
0.36	GO:1990525	BIR domain binding
0.35	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.33	GO:0004252	serine-type endopeptidase activity

0.46	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.38	GO:0031264	death-inducing signaling complex
0.37	GO:0098857	membrane microdomain
0.36	GO:0097179	protease inhibitor complex
0.35	GO:0043197	dendritic spine
0.35	GO:0014069	postsynaptic density
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part

0.75

GO:0004197

sp|O93436|STAM2_CHICK
Signal transducing adapter molecule 2
Search

STAM2

0.97	Signal transducing adapter molecule 2

0.69	GO:0006886	intracellular protein transport
0.36	GO:1903551	regulation of extracellular exosome assembly
0.36	GO:1903543	positive regulation of exosomal secretion
0.35	GO:0036258	multivesicular body assembly
0.35	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.34	GO:0016236	macroautophagy
0.34	GO:0016197	endosomal transport
0.34	GO:0016579	protein deubiquitination
0.33	GO:0061024	membrane organization
0.33	GO:0007165	signal transduction

0.36

GO:0005515

protein binding

0.47	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol
0.39	GO:0044440	endosomal part
0.38	GO:0005769	early endosome
0.37	GO:0098805	whole membrane
0.37	GO:0098588	bounding membrane of organelle
0.35	GO:0030139	endocytic vesicle
0.34	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

tr|O93468|O93468_CHICK
GTP-binding protein
Search

RHOB

0.48	Rho-related GTP-binding protein RhoB

0.76	GO:0007264	small GTPase mediated signal transduction
0.54	GO:0061154	endothelial tube morphogenesis
0.53	GO:0008333	endosome to lysosome transport
0.52	GO:0071479	cellular response to ionizing radiation
0.52	GO:0070301	cellular response to hydrogen peroxide
0.52	GO:0000281	mitotic cytokinesis
0.52	GO:0010595	positive regulation of endothelial cell migration
0.51	GO:0045766	positive regulation of angiogenesis
0.51	GO:0030336	negative regulation of cell migration
0.49	GO:0043065	positive regulation of apoptotic process

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.52	GO:0019003	GDP binding
0.38	GO:0019900	kinase binding
0.34	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.32	GO:0022857	transmembrane transporter activity

0.52	GO:0097610	cell surface furrow
0.51	GO:0032155	cell division site part
0.50	GO:0005770	late endosome
0.50	GO:0005769	early endosome
0.49	GO:0010008	endosome membrane
0.43	GO:0005634	nucleus
0.41	GO:0005886	plasma membrane
0.41	GO:0070451	cell hair
0.40	GO:0045179	apical cortex
0.40	GO:0044291	cell-cell contact zone

0.34

GO:0016620

tr|O93480|O93480_CHICK
Chromobox protein (CHCB1)
Search

CBX1

0.97	Chromobox protein like protein 1

0.45	GO:0045892	negative regulation of transcription, DNA-templated
0.35	GO:0043043	peptide biosynthetic process
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0010467	gene expression
0.34	GO:0009059	macromolecule biosynthetic process

0.54	GO:1990226	histone methyltransferase binding
0.46	GO:0042803	protein homodimerization activity
0.35	GO:0003735	structural constituent of ribosome
0.34	GO:0003682	chromatin binding
0.34	GO:0003779	actin binding

0.60	GO:0005634	nucleus
0.50	GO:0010369	chromocenter
0.50	GO:0005721	pericentric heterochromatin
0.49	GO:0000781	chromosome, telomeric region
0.48	GO:0005819	spindle
0.45	GO:0031974	membrane-enclosed lumen
0.35	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

sp|O93505|TYRP2_CHICK
L-dopachrome tautomerase
Search

DCT

0.97	L-dopachrome tautomerase variant

0.60	GO:0006583	melanin biosynthetic process from tyrosine
0.59	GO:0021847	ventricular zone neuroblast division
0.57	GO:0002052	positive regulation of neuroblast proliferation
0.55	GO:0048066	developmental pigmentation
0.52	GO:0055114	oxidation-reduction process
0.51	GO:0048468	cell development
0.35	GO:0008544	epidermis development

0.60	GO:0004167	dopachrome isomerase activity
0.53	GO:0016491	oxidoreductase activity
0.53	GO:0046872	metal ion binding

0.56	GO:0042470	melanosome
0.48	GO:0005829	cytosol
0.41	GO:0090741	pigment granule membrane
0.41	GO:0045009	chitosome
0.39	GO:0030659	cytoplasmic vesicle membrane
0.38	GO:0098805	whole membrane
0.30	GO:0016021	integral component of membrane

0.60	EC:5.3.3.12	GO:0004167
0.60	KEGG:R03673	GO:0004167

sp|O93510|GELS_CHICK
Gelsolin
Search

GSN

0.75	Actin-depolymerizing factor

0.84	GO:0051014	actin filament severing
0.84	GO:0051016	barbed-end actin filament capping
0.80	GO:0045010	actin nucleation
0.61	GO:1903923	positive regulation of protein processing in phagocytic vesicle
0.60	GO:0097017	renal protein absorption
0.59	GO:1902174	positive regulation of keratinocyte apoptotic process
0.58	GO:0014891	striated muscle atrophy
0.58	GO:1990000	amyloid fibril formation
0.58	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
0.58	GO:0097284	hepatocyte apoptotic process

0.78	GO:0051015	actin filament binding
0.70	GO:0005509	calcium ion binding
0.58	GO:0045159	myosin II binding

0.58	GO:0030478	actin cap
0.56	GO:0002102	podosome
0.55	GO:0016528	sarcoplasm
0.55	GO:0005925	focal adhesion
0.54	GO:0045335	phagocytic vesicle
0.53	GO:0030027	lamellipodium
0.50	GO:0005615	extracellular space
0.48	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.42	GO:0005886	plasma membrane

sp|O93512|GFRA4_CHICK
GDNF family receptor alpha-4
Search

0.94	GDNF family receptor alpha

0.45	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.44	GO:0007399	nervous system development
0.42	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.36	GO:0031953	negative regulation of protein autophosphorylation
0.34	GO:0000165	MAPK cascade
0.34	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.34	GO:0000904	cell morphogenesis involved in differentiation
0.34	GO:0120036	plasma membrane bounded cell projection organization
0.33	GO:0006935	chemotaxis
0.33	GO:0006928	movement of cell or subcellular component

0.64	GO:0004872	receptor activity
0.34	GO:0004871	signal transducer activity
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.58	GO:0031225	anchored component of membrane
0.44	GO:0005886	plasma membrane
0.34	GO:0019898	extrinsic component of membrane
0.31	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|O93525|NOGG_CHICK
Noggin
Search

NOG

0.96

Noggin

0.85	GO:0030514	negative regulation of BMP signaling pathway
0.79	GO:0045596	negative regulation of cell differentiation
0.73	GO:0051216	cartilage development
0.65	GO:0030154	cell differentiation
0.61	GO:0060825	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
0.61	GO:2000313	regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
0.60	GO:0060302	negative regulation of cytokine activity
0.60	GO:0090193	positive regulation of glomerulus development
0.59	GO:0060044	negative regulation of cardiac muscle cell proliferation
0.59	GO:0060513	prostatic bud formation

0.55	GO:0019955	cytokine binding
0.51	GO:0042803	protein homodimerization activity
0.34	GO:0032403	protein complex binding

0.60	GO:0005576	extracellular region
0.34	GO:0030424	axon
0.34	GO:0045202	synapse
0.33	GO:0005794	Golgi apparatus
0.32	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|O93526|FGL1L_CHICK
Fibrinogen-like protein 1-like protein
Search

0.38	Cytidine deaminase

0.51	GO:0006898	receptor-mediated endocytosis
0.50	GO:0009972	cytidine deamination
0.47	GO:0072377	blood coagulation, common pathway
0.46	GO:0043152	induction of bacterial agglutination
0.46	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.46	GO:0042730	fibrinolysis
0.45	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.45	GO:0045907	positive regulation of vasoconstriction
0.45	GO:2000352	negative regulation of endothelial cell apoptotic process
0.45	GO:0098609	cell-cell adhesion

0.56	GO:0005044	scavenger receptor activity
0.56	GO:0047844	deoxycytidine deaminase activity
0.50	GO:0004126	cytidine deaminase activity
0.43	GO:0030674	protein binding, bridging
0.43	GO:0050839	cell adhesion molecule binding
0.41	GO:0005102	receptor binding
0.40	GO:0016301	kinase activity
0.38	GO:0005198	structural molecule activity
0.38	GO:0030246	carbohydrate binding
0.35	GO:0046872	metal ion binding

0.45	GO:0031091	platelet alpha granule
0.45	GO:0005577	fibrinogen complex
0.43	GO:0009897	external side of plasma membrane
0.42	GO:0005938	cell cortex
0.41	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.56

EC:3.5.4.14

GO:0047844

sp|O93532|K2CO_CHICK
Keratin, type II cytoskeletal cochleal
Search

0.85	Keratin, type II cytoskeletal cochleal

0.40	GO:0009888	tissue development
0.39	GO:0042060	wound healing
0.39	GO:0097284	hepatocyte apoptotic process
0.38	GO:0030154	cell differentiation
0.38	GO:0048513	animal organ development
0.38	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.38	GO:0031099	regeneration
0.38	GO:0097191	extrinsic apoptotic signaling pathway
0.37	GO:0001701	in utero embryonic development
0.37	GO:0048589	developmental growth

0.62	GO:0005198	structural molecule activity
0.42	GO:0097110	scaffold protein binding
0.35	GO:0032403	protein complex binding

0.83	GO:0045095	keratin filament
0.39	GO:0070062	extracellular exosome
0.38	GO:0016327	apicolateral plasma membrane
0.38	GO:0042383	sarcolemma
0.38	GO:0030018	Z disc
0.37	GO:0016363	nuclear matrix
0.37	GO:0005911	cell-cell junction
0.36	GO:0043034	costamere
0.35	GO:0016010	dystrophin-associated glycoprotein complex
0.35	GO:0005654	nucleoplasm

sp|O93533|CXB6_CHICK
Gap junction beta-6 protein
Search

GJB6

0.64	Gap junction beta-6 protein (Fragment)

0.60	GO:0007154	cell communication
0.56	GO:0016264	gap junction assembly
0.53	GO:0007605	sensory perception of sound
0.51	GO:0043583	ear development
0.49	GO:0048562	embryonic organ morphogenesis
0.49	GO:0090596	sensory organ morphogenesis
0.43	GO:0023052	signaling
0.42	GO:0032496	response to lipopolysaccharide
0.42	GO:0007568	aging
0.41	GO:1905867	epididymis development

0.55	GO:0005243	gap junction channel activity
0.48	GO:0042802	identical protein binding

0.83	GO:0005922	connexin complex
0.40	GO:0097449	astrocyte projection
0.39	GO:0016328	lateral plasma membrane
0.39	GO:0005829	cytosol
0.39	GO:0016324	apical plasma membrane
0.38	GO:0044297	cell body
0.38	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.30	GO:0016021	integral component of membrane

sp|O93567|ZBT7A_CHICK
Zinc finger and BTB domain-containing protein 7A
Search

ZBTB7A

0.94	Zinc finger and BTB domain-containing protein 7A

0.52	GO:0006357	regulation of transcription by RNA polymerase II
0.51	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding
0.50	GO:0045600	positive regulation of fat cell differentiation
0.50	GO:0048523	negative regulation of cellular process
0.47	GO:0042127	regulation of cell proliferation
0.47	GO:0010558	negative regulation of macromolecule biosynthetic process
0.46	GO:0051172	negative regulation of nitrogen compound metabolic process
0.45	GO:0010629	negative regulation of gene expression
0.45	GO:0045893	positive regulation of transcription, DNA-templated
0.37	GO:0030154	cell differentiation

0.54	GO:0035035	histone acetyltransferase binding
0.52	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0046872	metal ion binding

0.43

GO:0005634

nucleus

sp|O93574|RELN_CHICK
Reelin (Fragment)
Search

RELN

0.56

Reelin

0.84	GO:0001764	neuron migration
0.78	GO:0007417	central nervous system development
0.55	GO:1902076	regulation of lateral motor column neuron migration
0.54	GO:1905485	positive regulation of motor neuron migration
0.54	GO:0097114	NMDA glutamate receptor clustering
0.54	GO:0097119	postsynaptic density protein 95 clustering
0.54	GO:2000969	positive regulation of AMPA receptor activity
0.54	GO:0090129	positive regulation of synapse maturation
0.54	GO:0061003	positive regulation of dendritic spine morphogenesis
0.54	GO:1900273	positive regulation of long-term synaptic potentiation

0.85	GO:0070325	lipoprotein particle receptor binding
0.44	GO:0015116	sulfate transmembrane transporter activity
0.34	GO:0017171	serine hydrolase activity
0.33	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.32	GO:0046872	metal ion binding
0.32	GO:0015291	secondary active transmembrane transporter activity

0.50	GO:0030425	dendrite
0.48	GO:0005578	proteinaceous extracellular matrix
0.47	GO:0005615	extracellular space
0.40	GO:0005886	plasma membrane
0.37	GO:0005737	cytoplasm
0.33	GO:0043204	perikaryon
0.33	GO:0030424	axon
0.30	GO:0016021	integral component of membrane

tr|O93582|O93582_CHICK
Paired type homeodomain protein
Search

ALX4

0.97	LOW QUALITY PROTEIN: homeobox protein aristaless-like 4

0.69	GO:0007275	multicellular organism development
0.66	GO:0006357	regulation of transcription by RNA polymerase II
0.57	GO:0060021	palate development
0.56	GO:0009653	anatomical structure morphogenesis
0.54	GO:0042981	regulation of apoptotic process
0.54	GO:0061061	muscle structure development
0.54	GO:0022405	hair cycle process
0.52	GO:0008544	epidermis development
0.52	GO:0006366	transcription by RNA polymerase II
0.51	GO:1904888	cranial skeletal system development

0.63	GO:0043565	sequence-specific DNA binding
0.59	GO:0071837	HMG box domain binding
0.58	GO:0003700	DNA binding transcription factor activity
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0046982	protein heterodimerization activity
0.50	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.52	GO:0005667	transcription factor complex

tr|O93601|O93601_CHICK
Apolipoprotein AIV
Search

APOA4

0.89	Apolipoprotein A-IV

0.75	GO:0042157	lipoprotein metabolic process
0.74	GO:0006869	lipid transport
0.73	GO:0010873	positive regulation of cholesterol esterification
0.73	GO:0034372	very-low-density lipoprotein particle remodeling
0.72	GO:0051006	positive regulation of lipoprotein lipase activity
0.71	GO:0045723	positive regulation of fatty acid biosynthetic process
0.71	GO:0010898	positive regulation of triglyceride catabolic process
0.71	GO:0065005	protein-lipid complex assembly
0.71	GO:0034444	regulation of plasma lipoprotein oxidation
0.70	GO:0030300	regulation of intestinal cholesterol absorption

0.74	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity
0.72	GO:0008289	lipid binding
0.71	GO:0050997	quaternary ammonium group binding
0.70	GO:0017127	cholesterol transporter activity
0.67	GO:0070405	ammonium ion binding
0.58	GO:0042803	protein homodimerization activity
0.56	GO:0005507	copper ion binding
0.55	GO:0043178	alcohol binding
0.55	GO:0016209	antioxidant activity
0.46	GO:0043168	anion binding

0.73	GO:0034364	high-density lipoprotein particle
0.73	GO:0042627	chylomicron
0.67	GO:0034361	very-low-density lipoprotein particle
0.59	GO:0031012	extracellular matrix
0.59	GO:0009986	cell surface
0.56	GO:0072562	blood microparticle
0.45	GO:0070062	extracellular exosome
0.41	GO:0005788	endoplasmic reticulum lumen
0.41	GO:0031410	cytoplasmic vesicle
0.38	GO:0005829	cytosol

sp|O93602|ATF2_CHICK
Cyclic AMP-dependent transcription factor ATF-2
Search

ATF2

0.93	Cyclic AMP-dependent transcription factor ATF-2

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.59	GO:0032915	positive regulation of transforming growth factor beta2 production
0.57	GO:0110024	positive regulation of cardiac muscle myoblast proliferation
0.56	GO:0060612	adipose tissue development
0.56	GO:1902110	positive regulation of mitochondrial membrane permeability involved in apoptotic process
0.55	GO:0003151	outflow tract morphogenesis
0.54	GO:0045444	fat cell differentiation
0.54	GO:0031573	intra-S DNA damage checkpoint
0.53	GO:0016525	negative regulation of angiogenesis
0.52	GO:0051091	positive regulation of DNA binding transcription factor activity

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0008140	cAMP response element binding protein binding
0.54	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.54	GO:0035497	cAMP response element binding
0.54	GO:0001102	RNA polymerase II activating transcription factor binding
0.52	GO:0004402	histone acetyltransferase activity
0.51	GO:0003682	chromatin binding
0.51	GO:0019901	protein kinase binding
0.36	GO:0046982	protein heterodimerization activity
0.34	GO:0003713	transcription coactivator activity

0.61	GO:0005634	nucleus
0.54	GO:0035861	site of double-strand break
0.51	GO:0005741	mitochondrial outer membrane
0.46	GO:0070013	intracellular organelle lumen
0.33	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.30	GO:0016021	integral component of membrane

0.52

EC:2.3.1.48

GO:0004402

sp|O93603|TRFR_CHICK
Thyrotropin-releasing hormone receptor
Search

TRHR

0.92	Thyrotropin-releasing hormone receptor b

0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:0090073	positive regulation of protein homodimerization activity
0.34	GO:0007204	positive regulation of cytosolic calcium ion concentration

0.85	GO:0004997	thyrotropin-releasing hormone receptor activity
0.34	GO:0042803	protein homodimerization activity

0.35	GO:0005886	plasma membrane
0.34	GO:0009986	cell surface
0.30	GO:0044425	membrane part

sp|P00174|CYB5_CHICK
Cytochrome b5
Search

CYB5A

0.64	Microsomal cytochrome b5 type A

0.41	GO:0071466	cellular response to xenobiotic stimulus
0.39	GO:0046686	response to cadmium ion
0.36	GO:0055114	oxidation-reduction process
0.35	GO:0019852	L-ascorbic acid metabolic process
0.34	GO:0006091	generation of precursor metabolites and energy
0.34	GO:0006631	fatty acid metabolic process
0.33	GO:1902600	hydrogen ion transmembrane transport

0.58	GO:0020037	heme binding
0.50	GO:0046872	metal ion binding
0.49	GO:0019899	enzyme binding
0.35	GO:0004033	aldo-keto reductase (NADP) activity
0.35	GO:0004768	stearoyl-CoA 9-desaturase activity
0.34	GO:0009055	electron transfer activity
0.33	GO:0015002	heme-copper terminal oxidase activity
0.33	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.48	GO:0005829	cytosol
0.44	GO:0005739	mitochondrion
0.41	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0031090	organelle membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0031967	organelle envelope
0.34	GO:0098805	whole membrane
0.33	GO:0019867	outer membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:1.1.1

GO:0004033

sp|P00337|LDHB_CHICK
L-lactate dehydrogenase B chain
Search

LDHB

0.54	L-lactate dehydrogenase B chain

0.60	GO:0005975	carbohydrate metabolic process
0.57	GO:0019752	carboxylic acid metabolic process
0.52	GO:0055114	oxidation-reduction process
0.37	GO:0019674	NAD metabolic process
0.36	GO:1901615	organic hydroxy compound metabolic process
0.33	GO:0016053	organic acid biosynthetic process
0.32	GO:0006091	generation of precursor metabolites and energy
0.32	GO:0009059	macromolecule biosynthetic process
0.32	GO:0044260	cellular macromolecule metabolic process

0.81	GO:0004459	L-lactate dehydrogenase activity
0.48	GO:0042802	identical protein binding
0.37	GO:0019900	kinase binding
0.36	GO:0051287	NAD binding
0.35	GO:0005212	structural constituent of eye lens
0.34	GO:0004373	glycogen (starch) synthase activity

0.51	GO:0043209	myelin sheath
0.51	GO:0045121	membrane raft
0.48	GO:0005737	cytoplasm
0.41	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.81

EC:1.1.1.27

GO:0004459

sp|P00340|LDHA_CHICK
L-lactate dehydrogenase A chain
Search

LDHA

0.54	L-lactate dehydrogenase A chain

0.60	GO:0005975	carbohydrate metabolic process
0.57	GO:0019752	carboxylic acid metabolic process
0.52	GO:0055114	oxidation-reduction process
0.37	GO:0051591	response to cAMP
0.37	GO:0043627	response to estrogen
0.37	GO:0009749	response to glucose
0.37	GO:0042542	response to hydrogen peroxide
0.37	GO:0048569	post-embryonic animal organ development
0.37	GO:0001666	response to hypoxia
0.37	GO:0007584	response to nutrient

0.81	GO:0004459	L-lactate dehydrogenase activity
0.41	GO:0045296	cadherin binding
0.36	GO:0019900	kinase binding
0.36	GO:0042802	identical protein binding
0.35	GO:0051287	NAD binding

0.48	GO:0005737	cytoplasm
0.37	GO:0035686	sperm fibrous sheath
0.36	GO:0000439	core TFIIH complex
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.81

EC:1.1.1.27

GO:0004459

sp|P00356|G3P_CHICK
Glyceraldehyde-3-phosphate dehydrogenase
Search

GAPDH

0.52	Glyceraldehyde-3-phosphate dehydrogenase

0.67	GO:0006006	glucose metabolic process
0.67	GO:0006757	ATP generation from ADP
0.65	GO:0006090	pyruvate metabolic process
0.64	GO:0016052	carbohydrate catabolic process
0.64	GO:0019362	pyridine nucleotide metabolic process
0.52	GO:0055114	oxidation-reduction process
0.51	GO:0035606	peptidyl-cysteine S-trans-nitrosylation
0.49	GO:0051402	neuron apoptotic process
0.47	GO:0051873	killing by host of symbiont cells
0.46	GO:0050821	protein stabilization

0.78	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
0.66	GO:0050661	NADP binding
0.64	GO:0051287	NAD binding
0.52	GO:0035605	peptidyl-cysteine S-nitrosylase activity
0.47	GO:0019828	aspartic-type endopeptidase inhibitor activity
0.46	GO:0097718	disordered domain specific binding
0.45	GO:0008017	microtubule binding
0.42	GO:0042802	identical protein binding
0.35	GO:0019899	enzyme binding

0.53	GO:0097452	GAIT complex
0.46	GO:0005829	cytosol
0.44	GO:0005811	lipid droplet
0.44	GO:0031965	nuclear membrane
0.43	GO:0015630	microtubule cytoskeleton
0.39	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome

0.78

EC:1.2.1.12

GO:0004365

sp|P00368|DHE3_CHICK
Glutamate dehydrogenase 1, mitochondrial
Search

GLUD1

0.45	Glutamate dehydrogenase

0.57	GO:0006520	cellular amino acid metabolic process
0.50	GO:0055114	oxidation-reduction process
0.47	GO:0032024	positive regulation of insulin secretion
0.43	GO:0072350	tricarboxylic acid metabolic process
0.41	GO:0043649	dicarboxylic acid catabolic process
0.40	GO:0032094	response to food
0.39	GO:0043650	dicarboxylic acid biosynthetic process
0.38	GO:1901565	organonitrogen compound catabolic process
0.37	GO:0021762	substantia nigra development
0.37	GO:0010044	response to aluminum ion

0.71	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
0.43	GO:0070728	leucine binding
0.40	GO:0043531	ADP binding
0.39	GO:0032550	purine ribonucleoside binding
0.39	GO:0019001	guanyl nucleotide binding
0.38	GO:0070403	NAD+ binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005515	protein binding
0.35	GO:0008144	drug binding

0.46	GO:0005759	mitochondrial matrix
0.39	GO:0031966	mitochondrial membrane
0.39	GO:0019866	organelle inner membrane

0.71

EC:1.4.1

GO:0016639

sp|P00378|DYR_CHICK
Dihydrofolate reductase
Search

DHFR

0.43	Dihydrofolate reductase

0.75	GO:0046654	tetrahydrofolate biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0051000	positive regulation of nitric-oxide synthase activity
0.49	GO:2000121	regulation of removal of superoxide radicals
0.48	GO:0046146	tetrahydrobiopterin metabolic process
0.48	GO:0034312	diol biosynthetic process
0.45	GO:0031427	response to methotrexate
0.44	GO:0003232	bulbus arteriosus development
0.43	GO:0046452	dihydrofolate metabolic process
0.43	GO:0046655	folic acid metabolic process

0.79	GO:0004146	dihydrofolate reductase activity
0.44	GO:0051870	methotrexate binding
0.43	GO:0003729	mRNA binding
0.43	GO:0000900	translation repressor activity, nucleic acid binding
0.41	GO:0005542	folic acid binding
0.40	GO:0070402	NADPH binding
0.40	GO:0051871	dihydrofolic acid binding
0.36	GO:0033560	folate reductase activity
0.35	GO:0004799	thymidylate synthase activity
0.33	GO:0004386	helicase activity

0.43	GO:0005739	mitochondrion
0.35	GO:0005829	cytosol
0.34	GO:0070013	intracellular organelle lumen
0.34	GO:0019866	organelle inner membrane
0.34	GO:0000439	core TFIIH complex
0.30	GO:0016021	integral component of membrane

0.79	EC:1.5.1.3	GO:0004146
0.35	KEGG:R02101	GO:0004799

sp|P00504|AATC_CHICK
Aspartate aminotransferase, cytoplasmic
Search

GOT1

0.49	Aspartate aminotransferase

0.61	GO:0006532	aspartate biosynthetic process
0.61	GO:0006114	glycerol biosynthetic process
0.60	GO:0019550	glutamate catabolic process to aspartate
0.60	GO:0006533	aspartate catabolic process
0.58	GO:0055089	fatty acid homeostasis
0.56	GO:0051384	response to glucocorticoid
0.56	GO:0032869	cellular response to insulin stimulus
0.55	GO:0006103	2-oxoglutarate metabolic process
0.54	GO:0007219	Notch signaling pathway
0.54	GO:0006107	oxaloacetate metabolic process

0.81	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity
0.78	GO:0070546	L-phenylalanine aminotransferase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.53	GO:0004609	phosphatidylserine decarboxylase activity
0.47	GO:0047801	L-cysteine:2-oxoglutarate aminotransferase activity
0.37	GO:0031406	carboxylic acid binding

0.50	GO:0005829	cytosol
0.49	GO:0005654	nucleoplasm
0.39	GO:0005739	mitochondrion
0.39	GO:0043679	axon terminus
0.38	GO:0005764	lysosome
0.36	GO:0070062	extracellular exosome

0.81	EC:2.6.1.1	GO:0004069
0.81	KEGG:R00355	GO:0004069

sp|P00508|AATM_CHICK
Aspartate aminotransferase, mitochondrial
Search

GOT2

0.49	Aspartate aminotransferase

0.60	GO:0006520	cellular amino acid metabolic process
0.52	GO:0043649	dicarboxylic acid catabolic process
0.51	GO:0045471	response to ethanol
0.49	GO:0015908	fatty acid transport
0.49	GO:0009058	biosynthetic process
0.48	GO:0006103	2-oxoglutarate metabolic process
0.46	GO:1901565	organonitrogen compound catabolic process
0.46	GO:0006107	oxaloacetate metabolic process
0.45	GO:0006106	fumarate metabolic process
0.41	GO:0042537	benzene-containing compound metabolic process

0.82	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity
0.78	GO:0070546	L-phenylalanine aminotransferase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.45	GO:0016212	kynurenine-oxoglutarate transaminase activity
0.37	GO:0042803	protein homodimerization activity
0.36	GO:0016597	amino acid binding
0.36	GO:0005543	phospholipid binding
0.36	GO:0019899	enzyme binding
0.36	GO:0047578	4-hydroxyglutamate transaminase activity
0.34	GO:0090729	toxin activity

0.46	GO:0043209	myelin sheath
0.44	GO:0005739	mitochondrion
0.40	GO:0005886	plasma membrane
0.40	GO:0019866	organelle inner membrane
0.40	GO:0070013	intracellular organelle lumen
0.38	GO:0043204	perikaryon
0.37	GO:0009986	cell surface
0.36	GO:0070062	extracellular exosome
0.34	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.82	EC:2.6.1.1	GO:0004069
0.82	KEGG:R00355	GO:0004069

sp|P00523|SRC_CHICK
Proto-oncogene tyrosine-protein kinase Src
Search

SRC

0.53	Neuronal proto-oncogene tyrosine-protein kinase Src

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.57	GO:0036035	osteoclast development
0.56	GO:0071801	regulation of podosome assembly
0.56	GO:0045453	bone resorption
0.56	GO:2001286	regulation of caveolin-mediated endocytosis
0.55	GO:0051902	negative regulation of mitochondrial depolarization
0.55	GO:0086098	angiotensin-activated signaling pathway involved in heart process
0.55	GO:2000394	positive regulation of lamellipodium morphogenesis
0.55	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.55	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway

0.79	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0071253	connexin binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0042169	SH2 domain binding
0.53	GO:0070851	growth factor receptor binding
0.53	GO:0097110	scaffold protein binding
0.53	GO:0046875	ephrin receptor binding

0.53	GO:0002102	podosome
0.52	GO:0032587	ruffle membrane
0.52	GO:0005901	caveola
0.51	GO:0005884	actin filament
0.50	GO:0005770	late endosome
0.50	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005764	lysosome
0.46	GO:0005829	cytosol
0.45	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.43	GO:0031966	mitochondrial membrane

0.79	EC:2.7.10.2	GO:0004715
0.35	KEGG:R04545	GO:0046934

sp|P00548|KPYM_CHICK
Pyruvate kinase PKM
Search

PKM

0.46	Pyruvate kinase PKM

0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.47	GO:0012501	programmed cell death
0.45	GO:0032868	response to insulin
0.44	GO:0071375	cellular response to peptide hormone stimulus
0.38	GO:0014870	response to muscle inactivity
0.38	GO:0043403	skeletal muscle tissue regeneration
0.38	GO:0031100	animal organ regeneration

0.78	GO:0004743	pyruvate kinase activity
0.77	GO:0030955	potassium ion binding
0.64	GO:0000287	magnesium ion binding
0.60	GO:0016301	kinase activity
0.48	GO:0045296	cadherin binding
0.38	GO:0070324	thyroid hormone binding
0.37	GO:0023026	MHC class II protein complex binding
0.36	GO:0043531	ADP binding
0.36	GO:0042802	identical protein binding
0.36	GO:0005524	ATP binding

0.48	GO:0043209	myelin sheath
0.46	GO:0005929	cilium
0.45	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.41	GO:0005739	mitochondrion
0.39	GO:1902912	pyruvate kinase complex
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen

0.78

EC:2.7.1.40

GO:0004743

sp|P00565|KCRM_CHICK
Creatine kinase M-type
Search

CKM

0.92	Brain-subtype creatine kinase

0.56	GO:0016310	phosphorylation
0.56	GO:0046314	phosphocreatine biosynthetic process
0.49	GO:0009408	response to heat
0.35	GO:0006600	creatine metabolic process

0.65	GO:0004111	creatine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0031625	ubiquitin protein ligase binding

0.49	GO:0005615	extracellular space
0.37	GO:0043209	myelin sheath
0.37	GO:0005829	cytosol
0.34	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.65	EC:2.7.3.2	GO:0004111
0.65	KEGG:R01881	GO:0004111

sp|P00698|LYSC_CHICK
Lysozyme C
Search

LYZ

0.52	Lysozyme C, kidney isozyme

0.77	GO:0042742	defense response to bacterium
0.76	GO:0019835	cytolysis
0.40	GO:0031640	killing of cells of other organism
0.39	GO:0016998	cell wall macromolecule catabolic process
0.37	GO:0044041	multi-organism carbohydrate catabolic process
0.37	GO:0044278	cell wall disruption in other organism
0.34	GO:0009253	peptidoglycan catabolic process
0.34	GO:0050832	defense response to fungus
0.34	GO:0032496	response to lipopolysaccharide

0.78	GO:0003796	lysozyme activity
0.39	GO:0042802	identical protein binding
0.36	GO:0016231	beta-N-acetylglucosaminidase activity
0.35	GO:0005539	glycosaminoglycan binding

0.48	GO:0005576	extracellular region
0.34	GO:0005783	endoplasmic reticulum

0.78

EC:3.2.1.17

GO:0003796

sp|P00789|CANX_CHICK
Calpain-1 catalytic subunit
Search

0.86	Calpain-1 catalytic subunit

0.61	GO:0006508	proteolysis
0.47	GO:0060056	mammary gland involution
0.44	GO:0032801	receptor catabolic process
0.43	GO:0021785	branchiomotor neuron axon guidance
0.42	GO:0050790	regulation of catalytic activity
0.40	GO:0007420	brain development
0.37	GO:0043066	negative regulation of apoptotic process
0.35	GO:0051493	regulation of cytoskeleton organization
0.33	GO:0051604	protein maturation

0.82	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.70	GO:0005509	calcium ion binding
0.33	GO:0008092	cytoskeletal protein binding

0.45	GO:0005622	intracellular
0.40	GO:0097223	sperm part
0.39	GO:0005886	plasma membrane
0.38	GO:0043227	membrane-bounded organelle
0.37	GO:0012505	endomembrane system
0.34	GO:0005925	focal adhesion
0.34	GO:0043230	extracellular organelle
0.33	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

sp|P00793|PEPA_CHICK
Pepsin A
Search

0.93	Pepsinogen A

0.61	GO:0006508	proteolysis
0.49	GO:0007586	digestion
0.48	GO:0006914	autophagy
0.45	GO:0030163	protein catabolic process
0.37	GO:0051604	protein maturation
0.37	GO:0002803	positive regulation of antibacterial peptide production
0.36	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.34	GO:0044267	cellular protein metabolic process

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.34	GO:0042803	protein homodimerization activity

0.42	GO:0005576	extracellular region
0.39	GO:0097486	multivesicular body lumen
0.30	GO:0016020	membrane

sp|P00940|TPIS_CHICK
Triosephosphate isomerase
Search

TPI1

0.47	Triosephosphate isomerase A

0.73	GO:0019319	hexose biosynthetic process
0.72	GO:0006098	pentose-phosphate shunt
0.71	GO:0006006	glucose metabolic process
0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.49	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process
0.45	GO:0046174	polyol catabolic process
0.44	GO:0006071	glycerol metabolic process
0.44	GO:0007275	multicellular organism development

0.78	GO:0004807	triose-phosphate isomerase activity
0.48	GO:0031625	ubiquitin protein ligase binding

0.42	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus

0.78	EC:5.3.1.1	GO:0004807
0.78	KEGG:R01015	GO:0004807

sp|P01005|IOVO_CHICK
Ovomucoid
Search

0.88

Ovomucoid

0.76	GO:0010951	negative regulation of endopeptidase activity
0.39	GO:0048545	response to steroid hormone

0.79	GO:0004867	serine-type endopeptidase inhibitor activity
0.41	GO:0019864	IgG binding
0.41	GO:0019863	IgE binding
0.37	GO:0030246	carbohydrate binding

0.65	GO:0005576	extracellular region
0.37	GO:0005783	endoplasmic reticulum
0.36	GO:0043234	protein complex

sp|P01012|OVAL_CHICK
Ovalbumin
Search

0.80	Heterochromatin-associated protein MENT

0.54	GO:0010951	negative regulation of endopeptidase activity
0.39	GO:0051412	response to corticosterone
0.38	GO:0042270	protection from natural killer cell mediated cytotoxicity
0.37	GO:0043627	response to estrogen
0.37	GO:0080144	amino acid homeostasis
0.37	GO:0032570	response to progesterone
0.36	GO:0050830	defense response to Gram-positive bacterium
0.36	GO:0050829	defense response to Gram-negative bacterium
0.36	GO:0009792	embryo development ending in birth or egg hatching
0.35	GO:0006508	proteolysis

0.55	GO:0004867	serine-type endopeptidase inhibitor activity
0.39	GO:0002020	protease binding
0.36	GO:0008201	heparin binding
0.35	GO:0008233	peptidase activity
0.35	GO:0005509	calcium ion binding
0.34	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process

0.73	GO:0005615	extracellular space
0.38	GO:0031905	early endosome lumen
0.37	GO:0032010	phagolysosome
0.35	GO:0005829	cytosol
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0005634	nucleus
0.33	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0008233

sp|P01013|OVALX_CHICK
Ovalbumin-related protein X (Fragment)
Search

0.81	Leukocyte elastase inhibitor A

0.55	GO:0010951	negative regulation of endopeptidase activity
0.37	GO:0051412	response to corticosterone
0.36	GO:0050830	defense response to Gram-positive bacterium
0.36	GO:0050829	defense response to Gram-negative bacterium
0.35	GO:0042270	protection from natural killer cell mediated cytotoxicity
0.35	GO:0043627	response to estrogen
0.35	GO:0032501	multicellular organismal process
0.34	GO:0080144	amino acid homeostasis
0.34	GO:0071470	cellular response to osmotic stress
0.34	GO:0007548	sex differentiation

0.56	GO:0004867	serine-type endopeptidase inhibitor activity
0.37	GO:0002020	protease binding
0.36	GO:0008201	heparin binding
0.33	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.33	GO:0005509	calcium ion binding
0.32	GO:0008233	peptidase activity

0.73	GO:0005615	extracellular space
0.37	GO:0031012	extracellular matrix
0.36	GO:1903561	extracellular vesicle
0.35	GO:0097180	serine protease inhibitor complex
0.35	GO:0031905	early endosome lumen
0.34	GO:0032010	phagolysosome
0.33	GO:0005829	cytosol
0.33	GO:0005783	endoplasmic reticulum
0.33	GO:0005634	nucleus
0.33	GO:0005794	Golgi apparatus

0.32

GO:0008233

sp|P01014|OVALY_CHICK
Ovalbumin-related protein Y
Search

0.79	Heterochromatin-associated protein MENT

0.50	GO:0010951	negative regulation of endopeptidase activity
0.38	GO:0051412	response to corticosterone
0.37	GO:0050830	defense response to Gram-positive bacterium
0.37	GO:0050829	defense response to Gram-negative bacterium
0.36	GO:0043627	response to estrogen
0.36	GO:0080144	amino acid homeostasis
0.35	GO:0032570	response to progesterone
0.35	GO:0009792	embryo development ending in birth or egg hatching
0.34	GO:0042270	protection from natural killer cell mediated cytotoxicity
0.34	GO:0002448	mast cell mediated immunity

0.51	GO:0004867	serine-type endopeptidase inhibitor activity
0.37	GO:0008201	heparin binding
0.36	GO:0002020	protease binding
0.34	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.34	GO:0005509	calcium ion binding

0.73	GO:0005615	extracellular space
0.36	GO:0031905	early endosome lumen
0.36	GO:0032010	phagolysosome
0.34	GO:0005829	cytosol
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0005794	Golgi apparatus
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

sp|P01038|CYT_CHICK
Cystatin
Search

0.72

Cystatin

0.76	GO:0010951	negative regulation of endopeptidase activity
0.49	GO:2000116	regulation of cysteine-type endopeptidase activity
0.41	GO:0010711	negative regulation of collagen catabolic process
0.41	GO:0060311	negative regulation of elastin catabolic process
0.40	GO:0060313	negative regulation of blood vessel remodeling
0.40	GO:0010716	negative regulation of extracellular matrix disassembly
0.37	GO:0097435	supramolecular fiber organization
0.37	GO:0006952	defense response
0.34	GO:0006955	immune response

0.83	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.51	GO:0002020	protease binding
0.39	GO:0001540	amyloid-beta binding
0.37	GO:0042802	identical protein binding

0.47	GO:0005615	extracellular space
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P01103|MYB_CHICK
Transcriptional activator Myb
Search

MYB

0.90	Transcriptional activator Myb

0.57	GO:0045624	positive regulation of T-helper cell differentiation
0.57	GO:0051574	positive regulation of histone H3-K9 methylation
0.57	GO:0051571	positive regulation of histone H3-K4 methylation
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.51	GO:0006338	chromatin remodeling
0.51	GO:0051254	positive regulation of RNA metabolic process
0.51	GO:0010557	positive regulation of macromolecule biosynthetic process
0.51	GO:0031328	positive regulation of cellular biosynthetic process

0.54	GO:0003677	DNA binding
0.52	GO:0001067	regulatory region nucleic acid binding
0.47	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.44	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.39	GO:0071987	WD40-repeat domain binding

0.40	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome
0.30	GO:0016020	membrane

sp|P01109|MYC_CHICK
Myc proto-oncogene protein
Search

MYC

0.80	MYC proto-oncogene, bHLH transcription factor

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.36	GO:0048730	epidermis morphogenesis
0.34	GO:0016032	viral process
0.33	GO:0006351	transcription, DNA-templated

0.68	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.37	GO:0003677	DNA binding
0.35	GO:0005198	structural molecule activity

0.60	GO:0005634	nucleus
0.42	GO:0042025	host cell nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0019028	viral capsid
0.35	GO:0044446	intracellular organelle part

sp|P01280|SECR_CHICK
Secretin
Search

0.37

Secretin

0.76

GO:0010469

regulation of receptor activity

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|P01295|GRP_CHICK
Gastrin-releasing peptide
Search

GRP

0.71	Gastrin-releasing peptide

0.80	GO:0007218	neuropeptide signaling pathway
0.76	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
0.71	GO:0010469	regulation of receptor activity
0.64	GO:0090277	positive regulation of peptide hormone secretion
0.63	GO:0036343	psychomotor behavior
0.60	GO:0035176	social behavior
0.51	GO:0043207	response to external biotic stimulus

0.80

GO:0005184

neuropeptide hormone activity

0.66	GO:0034774	secretory granule lumen
0.61	GO:0005615	extracellular space

sp|P01875|IGHM_CHICK
Ig mu chain C region
Search

IGHM

0.69	Ig mu chain C region

0.73	GO:0030890	positive regulation of B cell proliferation
0.72	GO:0006958	complement activation, classical pathway

0.82

GO:0003823

antigen binding

0.57	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|P01994|HBA_CHICK
Hemoglobin subunit alpha-A
Search

HBA2

0.82	Hemoglobin subunit alpha-A

0.79

GO:0015671

oxygen transport

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.33	GO:0005515	protein binding

0.82	GO:0005833	hemoglobin complex
0.34	GO:0005615	extracellular space

sp|P02001|HBAD_CHICK
Hemoglobin subunit alpha-D
Search

0.96	Hemoglobin subunit alpha-D

0.79

GO:0015671

oxygen transport

0.79	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.62	GO:0005506	iron ion binding

0.82

GO:0005833

hemoglobin complex

sp|P02007|HBPI_CHICK
Hemoglobin subunit pi
Search

HBZ

0.97	Hemoglobin subunit zeta

0.79	GO:0015671	oxygen transport
0.52	GO:0043249	erythrocyte maturation
0.47	GO:0000122	negative regulation of transcription by RNA polymerase II

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.34	GO:0005515	protein binding

0.83	GO:0005833	hemoglobin complex
0.36	GO:0070062	extracellular exosome

sp|P02112|HBB_CHICK
Hemoglobin subunit beta
Search

HBB

0.85	Hemoglobin beta A subunit

0.79

GO:0015671

oxygen transport

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.35	GO:0030492	hemoglobin binding

0.83	GO:0005833	hemoglobin complex
0.34	GO:0005615	extracellular space

sp|P02127|HBRH_CHICK
Hemoglobin subunit rho
Search

HBB

0.80	Hemoglobin subunit epsilon

0.76

GO:0015671

oxygen transport

0.77	GO:0005344	oxygen carrier activity
0.77	GO:0019825	oxygen binding
0.61	GO:0020037	heme binding
0.61	GO:0005506	iron ion binding
0.35	GO:0030492	hemoglobin binding

0.80	GO:0005833	hemoglobin complex
0.34	GO:0005615	extracellular space

sp|P02128|HBE_CHICK
Hemoglobin subunit epsilon
Search

HBB

0.79	Hemoglobin subunit epsilon

0.78

GO:0015671

oxygen transport

0.79	GO:0005344	oxygen carrier activity
0.78	GO:0019825	oxygen binding
0.62	GO:0020037	heme binding
0.62	GO:0005506	iron ion binding
0.35	GO:0030492	hemoglobin binding

0.82	GO:0005833	hemoglobin complex
0.34	GO:0005615	extracellular space

sp|P02197|MYG_CHICK
Myoglobin
Search

0.84

Myoglobin

0.78	GO:0015671	oxygen transport
0.49	GO:0043353	enucleate erythrocyte differentiation
0.46	GO:0001666	response to hypoxia
0.45	GO:0007507	heart development
0.44	GO:0050873	brown fat cell differentiation
0.41	GO:0031444	slow-twitch skeletal muscle fiber contraction
0.39	GO:0042542	response to hydrogen peroxide
0.38	GO:0009725	response to hormone

0.78	GO:0019825	oxygen binding
0.78	GO:0005344	oxygen carrier activity
0.62	GO:0020037	heme binding
0.53	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol

sp|P02259|H5_CHICK
Histone H5
Search

H1F0

0.53	Glycine C-acetyltransferase

0.79	GO:0006334	nucleosome assembly
0.40	GO:0030261	chromosome condensation
0.37	GO:0032439	endosome localization
0.36	GO:0001919	regulation of receptor recycling
0.36	GO:0042632	cholesterol homeostasis
0.36	GO:0071230	cellular response to amino acid stimulus
0.36	GO:0007040	lysosome organization
0.36	GO:0006567	threonine catabolic process
0.36	GO:0032008	positive regulation of TOR signaling
0.36	GO:0043410	positive regulation of MAPK cascade

0.55	GO:0003677	DNA binding
0.49	GO:0003682	chromatin binding
0.36	GO:0008890	glycine C-acetyltransferase activity
0.35	GO:0044877	macromolecular complex binding
0.34	GO:0030170	pyridoxal phosphate binding
0.34	GO:0016874	ligase activity
0.34	GO:0005515	protein binding
0.34	GO:0003723	RNA binding
0.33	GO:0042302	structural constituent of cuticle
0.32	GO:0008270	zinc ion binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.53	GO:0000791	euchromatin
0.48	GO:0015629	actin cytoskeleton
0.47	GO:0005794	Golgi apparatus
0.45	GO:0031974	membrane-enclosed lumen
0.36	GO:0071986	Ragulator complex
0.30	GO:0031224	intrinsic component of membrane

0.36	EC:2.3.1.29	GO:0008890
0.36	KEGG:R00371	GO:0008890

sp|P02263|H2A4_CHICK
Histone H2A-IV
Search

sp|P02272|H2AV_CHICK
Histone H2A.V
Search

sp|P02314|HMGN2_CHICK
Non-histone chromosomal protein HMG-17
Search

HMGN2

0.94	High mobility group nucleosome-binding domain-containing protein 4

0.38	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.37	GO:0031640	killing of cells of other organism
0.36	GO:0040034	regulation of development, heterochronic
0.35	GO:0000122	negative regulation of transcription by RNA polymerase II
0.33	GO:0006486	protein glycosylation
0.33	GO:0006508	proteolysis

0.85	GO:0031492	nucleosomal DNA binding
0.34	GO:0004181	metallocarboxypeptidase activity
0.34	GO:0003723	RNA binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding
0.33	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups
0.33	GO:0008270	zinc ion binding

0.72	GO:0000785	chromatin
0.61	GO:0005634	nucleus
0.36	GO:0005615	extracellular space
0.34	GO:0005737	cytoplasm

0.34

EC:3.4.17

GO:0004181

sp|P02450|KRFC_CHICK
Feather keratin 1
Search

0.80	Feather beta keratin

0.71

GO:0007010

cytoskeleton organization

0.77

GO:0005200

structural constituent of cytoskeleton

0.79

GO:0005882

intermediate filament

sp|P02457|CO1A1_CHICK
Collagen alpha-1(I) chain
Search

COL1A1

0.82	Collagen type II alpha 1 chain

0.58	GO:0030199	collagen fibril organization
0.58	GO:0032964	collagen biosynthetic process
0.58	GO:0034505	tooth mineralization
0.58	GO:0001958	endochondral ossification
0.58	GO:0043589	skin morphogenesis
0.58	GO:0060351	cartilage development involved in endochondral bone morphogenesis
0.57	GO:0001957	intramembranous ossification
0.57	GO:0060346	bone trabecula formation
0.57	GO:0070208	protein heterotrimerization
0.56	GO:0048706	embryonic skeletal system development

0.77	GO:0005201	extracellular matrix structural constituent
0.60	GO:0048407	platelet-derived growth factor binding
0.55	GO:0002020	protease binding
0.51	GO:0042802	identical protein binding
0.42	GO:0042289	MHC class II protein binding
0.36	GO:0046872	metal ion binding

0.72	GO:0005581	collagen trimer
0.60	GO:0098643	banded collagen fibril
0.53	GO:0005615	extracellular space
0.40	GO:0005604	basement membrane
0.39	GO:0005737	cytoplasm
0.36	GO:0097708	intracellular vesicle
0.36	GO:0012505	endomembrane system
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|P02460|CO2A1_CHICK
Collagen alpha-1(II) chain (Fragment)
Search

COL2A1

0.60	Collagen, type II, alpha 1 (Fragment)

0.50	GO:0030903	notochord development
0.47	GO:0007411	axon guidance
0.41	GO:0033334	fin morphogenesis

0.82

GO:0005201

extracellular matrix structural constituent

0.62

GO:0005581

collagen trimer

sp|P02467|CO1A2_CHICK
Collagen alpha-2(I) chain (Fragments)
Search

COL1A2

0.93	Procollagen type I alpha 2 chain

0.59	GO:0043589	skin morphogenesis
0.59	GO:0070208	protein heterotrimerization
0.57	GO:0030199	collagen fibril organization
0.56	GO:0007266	Rho protein signal transduction
0.56	GO:0071230	cellular response to amino acid stimulus
0.55	GO:0007179	transforming growth factor beta receptor signaling pathway
0.55	GO:0008217	regulation of blood pressure
0.54	GO:0001501	skeletal system development
0.54	GO:0001568	blood vessel development
0.47	GO:0009612	response to mechanical stimulus

0.81	GO:0005201	extracellular matrix structural constituent
0.59	GO:0048407	platelet-derived growth factor binding
0.56	GO:0002020	protease binding
0.56	GO:0046332	SMAD binding
0.54	GO:0030674	protein binding, bridging
0.51	GO:0042802	identical protein binding
0.35	GO:0046872	metal ion binding

0.67	GO:0005581	collagen trimer
0.60	GO:0098643	banded collagen fibril
0.52	GO:0005615	extracellular space
0.50	GO:0005783	endoplasmic reticulum
0.36	GO:1903561	extracellular vesicle
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P02504|CRYAA_CHICK
Alpha-crystallin A chain
Search

CRYAA

0.93	Alpha-crystallin A chain

0.45	GO:0070309	lens fiber cell morphogenesis
0.44	GO:0070141	response to UV-A
0.44	GO:0060561	apoptotic process involved in morphogenesis
0.44	GO:0048596	embryonic camera-type eye morphogenesis
0.43	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.43	GO:0007021	tubulin complex assembly
0.43	GO:0042542	response to hydrogen peroxide
0.43	GO:0030307	positive regulation of cell growth
0.42	GO:0001666	response to hypoxia
0.41	GO:0001934	positive regulation of protein phosphorylation

0.85	GO:0005212	structural constituent of eye lens
0.38	GO:0046872	metal ion binding
0.34	GO:0042802	identical protein binding
0.34	GO:0051082	unfolded protein binding

0.37	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.35	GO:0070062	extracellular exosome

sp|P02521|ARLY1_CHICK
Delta-1 crystallin
Search

ASL

0.68	Delta-1 crystallin

0.77

GO:0042450

arginine biosynthetic process via ornithine

0.77	GO:0004056	argininosuccinate lyase activity
0.57	GO:0005212	structural constituent of eye lens

0.41

GO:0005829

cytosol

0.77

EC:4.3.2.1

GO:0004056

sp|P02542|DESM_CHICK
Desmin
Search

DES

0.97	Muscle-specific intermediate filament desmin (Predicted)

0.58	GO:0045109	intermediate filament organization
0.47	GO:0006936	muscle contraction
0.46	GO:0060538	skeletal muscle organ development
0.46	GO:0007626	locomotory behavior
0.44	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling
0.43	GO:0045214	sarcomere organization
0.43	GO:0060047	heart contraction
0.42	GO:0009888	tissue development
0.39	GO:0010714	positive regulation of collagen metabolic process
0.39	GO:0032965	regulation of collagen biosynthetic process

0.62	GO:0005198	structural molecule activity
0.50	GO:0042802	identical protein binding
0.48	GO:0008092	cytoskeletal protein binding
0.40	GO:1990254	keratin filament binding
0.39	GO:0097110	scaffold protein binding
0.38	GO:0008022	protein C-terminus binding
0.37	GO:0019904	protein domain specific binding
0.37	GO:0003725	double-stranded RNA binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding

0.79	GO:0005882	intermediate filament
0.58	GO:0030018	Z disc
0.57	GO:0005916	fascia adherens
0.57	GO:0097512	cardiac myofibril
0.55	GO:0042383	sarcolemma
0.55	GO:0031594	neuromuscular junction
0.45	GO:0097433	dense body
0.44	GO:0005634	nucleus
0.38	GO:0005844	polysome
0.38	GO:0031982	vesicle

0.33

GO:0004674

sp|P02552|TBA1_CHICK
Tubulin alpha-1 chain (Fragment)
Search

0.53	Tubulin alpha chain

0.71	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.44	GO:0071353	cellular response to interleukin-4
0.37	GO:0021634	optic nerve formation
0.37	GO:0030705	cytoskeleton-dependent intracellular transport
0.35	GO:0043066	negative regulation of apoptotic process
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0051301	cell division
0.34	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle

0.77	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0031625	ubiquitin protein ligase binding
0.42	GO:0003725	double-stranded RNA binding
0.36	GO:0019904	protein domain specific binding
0.34	GO:0046982	protein heterodimerization activity

0.73	GO:0005874	microtubule
0.48	GO:0005737	cytoplasm
0.48	GO:0043209	myelin sheath
0.42	GO:0035770	ribonucleoprotein granule
0.42	GO:0031982	vesicle
0.39	GO:0045121	membrane raft
0.39	GO:0012505	endomembrane system
0.38	GO:0043230	extracellular organelle
0.37	GO:0005615	extracellular space
0.34	GO:0005634	nucleus

sp|P02565|MYH1B_CHICK
Myosin-1B
Search

0.72	Fast myosin heavy chain HCIII

0.74	GO:0007018	microtubule-based movement
0.52	GO:0006936	muscle contraction
0.50	GO:0014823	response to activity
0.49	GO:0033275	actin-myosin filament sliding
0.47	GO:0050881	musculoskeletal movement
0.40	GO:0046034	ATP metabolic process
0.38	GO:0001778	plasma membrane repair
0.38	GO:0031034	myosin filament assembly
0.35	GO:0035994	response to muscle stretch
0.35	GO:0009629	response to gravity

0.78	GO:0051015	actin filament binding
0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0000146	microfilament motor activity
0.45	GO:0005516	calmodulin binding
0.41	GO:0016887	ATPase activity
0.38	GO:0003725	double-stranded RNA binding

0.77	GO:0016459	myosin complex
0.55	GO:0043292	contractile fiber
0.46	GO:0036464	cytoplasmic ribonucleoprotein granule
0.45	GO:0014704	intercalated disc
0.38	GO:0005826	actomyosin contractile ring
0.36	GO:0005794	Golgi apparatus
0.35	GO:0005829	cytosol

0.41

GO:0016887

sp|P02588|TNNC2_CHICK
Troponin C, skeletal muscle
Search

TNNC2

0.94	Fast skeletal muscle troponin C

0.57	GO:0006941	striated muscle contraction
0.54	GO:0050881	musculoskeletal movement
0.51	GO:0006937	regulation of muscle contraction
0.47	GO:0014883	transition between fast and slow fiber
0.47	GO:0060047	heart contraction
0.46	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.46	GO:1903115	regulation of actin filament-based movement
0.44	GO:0032386	regulation of intracellular transport
0.43	GO:0043462	regulation of ATPase activity
0.42	GO:0014823	response to activity

0.70	GO:0005509	calcium ion binding
0.53	GO:0048306	calcium-dependent protein binding
0.51	GO:0003779	actin binding
0.48	GO:0031014	troponin T binding
0.48	GO:0032403	protein complex binding
0.48	GO:0031013	troponin I binding
0.43	GO:0042803	protein homodimerization activity
0.34	GO:0047617	acyl-CoA hydrolase activity

0.56	GO:0036379	myofilament
0.55	GO:0030017	sarcomere
0.51	GO:0015629	actin cytoskeleton
0.49	GO:0044430	cytoskeletal part
0.44	GO:0043234	protein complex
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.1.2 EC:3.1.2.20

GO:0047617

sp|P02597|CALMS_CHICK
Calmodulin, striated muscle
Search

0.48	Calmodulin, striated muscle

0.34	GO:0035023	regulation of Rho protein signal transduction
0.33	GO:0065009	regulation of molecular function
0.33	GO:0035556	intracellular signal transduction
0.33	GO:0006468	protein phosphorylation

0.70	GO:0005509	calcium ion binding
0.35	GO:0004689	phosphorylase kinase activity
0.35	GO:0005515	protein binding
0.33	GO:0098772	molecular function regulator

0.36	GO:0070062	extracellular exosome
0.33	GO:0005856	cytoskeleton
0.33	GO:0042995	cell projection
0.32	GO:0005737	cytoplasm

0.35

EC:2.7.11.19

GO:0004689

sp|P02604|MLE1_CHICK
Myosin light chain 1, skeletal muscle isoform
Search

MYL1

0.94	Myosin essential light chain fast

0.55	GO:0006936	muscle contraction
0.45	GO:0060047	heart contraction
0.42	GO:0014706	striated muscle tissue development
0.41	GO:0061061	muscle structure development
0.41	GO:0002026	regulation of the force of heart contraction
0.41	GO:0003007	heart morphogenesis
0.40	GO:0006942	regulation of striated muscle contraction
0.40	GO:0003231	cardiac ventricle development
0.39	GO:0048729	tissue morphogenesis
0.37	GO:0030029	actin filament-based process

0.70	GO:0005509	calcium ion binding
0.40	GO:0003785	actin monomer binding
0.36	GO:0008307	structural constituent of muscle
0.36	GO:0003774	motor activity
0.35	GO:0032038	myosin II heavy chain binding
0.34	GO:0051015	actin filament binding
0.33	GO:0003995	acyl-CoA dehydrogenase activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.54	GO:0030016	myofibril
0.42	GO:0016459	myosin complex
0.40	GO:0044449	contractile fiber part
0.34	GO:0005829	cytosol

0.33

EC:1.3.99.3

GO:0003995

sp|P02605|MLE3_CHICK
Myosin light chain 3, skeletal muscle isoform
Search

MYL1

0.97	Myosin light chain 1 transcript variant 1

0.54	GO:0006936	muscle contraction
0.45	GO:0060047	heart contraction
0.41	GO:0014706	striated muscle tissue development
0.41	GO:0002026	regulation of the force of heart contraction
0.41	GO:0061061	muscle structure development
0.41	GO:0003007	heart morphogenesis
0.40	GO:0006942	regulation of striated muscle contraction
0.39	GO:0003231	cardiac ventricle development
0.38	GO:0048729	tissue morphogenesis
0.37	GO:0030029	actin filament-based process

0.70	GO:0005509	calcium ion binding
0.40	GO:0003785	actin monomer binding
0.36	GO:0008307	structural constituent of muscle
0.35	GO:0003774	motor activity
0.35	GO:0032038	myosin II heavy chain binding
0.34	GO:0051015	actin filament binding
0.34	GO:0003995	acyl-CoA dehydrogenase activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.53	GO:0030016	myofibril
0.41	GO:0016459	myosin complex
0.40	GO:0044449	contractile fiber part
0.34	GO:0005829	cytosol

0.34

EC:1.3.99.3

GO:0003995

sp|P02606|MLEC_CHICK
Myosin light chain 1, cardiac muscle
Search

MYL3

0.91	Myosin light polypeptide 3

0.64	GO:0002026	regulation of the force of heart contraction
0.63	GO:0060047	heart contraction
0.62	GO:0006941	striated muscle contraction
0.55	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.54	GO:0006942	regulation of striated muscle contraction
0.49	GO:0032781	positive regulation of ATPase activity
0.39	GO:0055005	ventricular cardiac myofibril assembly
0.38	GO:0007519	skeletal muscle tissue development
0.38	GO:0045214	sarcomere organization
0.37	GO:0030049	muscle filament sliding

0.69	GO:0005509	calcium ion binding
0.62	GO:0003785	actin monomer binding
0.48	GO:0051015	actin filament binding
0.37	GO:0032038	myosin II heavy chain binding
0.37	GO:0003774	motor activity
0.35	GO:0008307	structural constituent of muscle
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0004872	receptor activity

0.62	GO:0031672	A band
0.54	GO:0031674	I band
0.42	GO:0016459	myosin complex
0.34	GO:0005829	cytosol
0.34	GO:0008305	integrin complex

0.33

GO:0004252

sp|P02607|MYL6_CHICK
Myosin light polypeptide 6
Search

MYL6

0.95	Smooth muscle myosin essential light chain

0.41	GO:0030049	muscle filament sliding
0.39	GO:0061061	muscle structure development
0.38	GO:0014706	striated muscle tissue development
0.37	GO:0048513	animal organ development
0.35	GO:0031032	actomyosin structure organization
0.35	GO:0010927	cellular component assembly involved in morphogenesis
0.34	GO:0048468	cell development
0.34	GO:0097435	supramolecular fiber organization
0.34	GO:0070925	organelle assembly
0.33	GO:0043043	peptide biosynthetic process

0.68	GO:0005509	calcium ion binding
0.50	GO:0008307	structural constituent of muscle
0.42	GO:0030898	actin-dependent ATPase activity
0.38	GO:0003774	motor activity
0.36	GO:0045159	myosin II binding
0.35	GO:0032036	myosin heavy chain binding
0.34	GO:0051015	actin filament binding
0.34	GO:0043531	ADP binding
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0000287	magnesium ion binding

0.50	GO:0016461	unconventional myosin complex
0.47	GO:0005903	brush border
0.38	GO:0070062	extracellular exosome
0.37	GO:0005829	cytosol
0.37	GO:0031012	extracellular matrix
0.37	GO:0005859	muscle myosin complex
0.36	GO:0097513	myosin II filament
0.35	GO:0042641	actomyosin
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

sp|P02609|MLRS_CHICK
Myosin regulatory light chain 2, skeletal muscle isoform
Search

MYLPF

0.92	Phosphorylatable fast skeletal muscle myosin light chain

0.53	GO:0007519	skeletal muscle tissue development
0.38	GO:0006936	muscle contraction
0.38	GO:0006955	immune response
0.36	GO:0042694	muscle cell fate specification
0.36	GO:0098735	positive regulation of the force of heart contraction
0.36	GO:0055003	cardiac myofibril assembly
0.36	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.36	GO:0048747	muscle fiber development
0.36	GO:0060047	heart contraction
0.36	GO:0030308	negative regulation of cell growth

0.70	GO:0005509	calcium ion binding
0.54	GO:0008307	structural constituent of muscle
0.36	GO:0003785	actin monomer binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0015629	actin cytoskeleton
0.39	GO:0043292	contractile fiber
0.39	GO:0044430	cytoskeletal part
0.37	GO:0043234	protein complex
0.36	GO:0005765	lysosomal membrane
0.33	GO:0005829	cytosol

0.33

GO:0004674

sp|P02610|MLRA_CHICK
Myosin regulatory light chain 2A, cardiac muscle isoform
Search

MYL2

0.93	Cardiac ventricular myosin light chain-2

0.57	GO:0098735	positive regulation of the force of heart contraction
0.56	GO:0042694	muscle cell fate specification
0.55	GO:0055003	cardiac myofibril assembly
0.54	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.54	GO:0060047	heart contraction
0.53	GO:0048747	muscle fiber development
0.53	GO:0006941	striated muscle contraction
0.52	GO:0030308	negative regulation of cell growth
0.50	GO:0009791	post-embryonic development
0.35	GO:0061049	cell growth involved in cardiac muscle cell development

0.69	GO:0005509	calcium ion binding
0.53	GO:0003785	actin monomer binding
0.35	GO:0032036	myosin heavy chain binding
0.35	GO:0008307	structural constituent of muscle

0.55	GO:0097512	cardiac myofibril
0.49	GO:0015629	actin cytoskeleton
0.40	GO:0031672	A band
0.38	GO:0044430	cytoskeletal part
0.36	GO:0043234	protein complex
0.36	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P02611|MLRB_CHICK
Myosin regulatory light chain 2B, cardiac muscle isoform
Search

MYL2

0.94	myosin regulatory light chain 2, ventricular/cardiac muscle isoform

0.54	GO:0098735	positive regulation of the force of heart contraction
0.54	GO:0042694	muscle cell fate specification
0.53	GO:0055003	cardiac myofibril assembly
0.51	GO:0060048	cardiac muscle contraction
0.51	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.51	GO:0048747	muscle fiber development
0.50	GO:0030308	negative regulation of cell growth
0.48	GO:0009791	post-embryonic development
0.35	GO:0061049	cell growth involved in cardiac muscle cell development
0.35	GO:0030049	muscle filament sliding

0.70	GO:0005509	calcium ion binding
0.51	GO:0003785	actin monomer binding
0.35	GO:0032036	myosin heavy chain binding
0.35	GO:0008307	structural constituent of muscle
0.33	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.53	GO:0097512	cardiac myofibril
0.47	GO:0015629	actin cytoskeleton
0.40	GO:0005739	mitochondrion
0.38	GO:0031672	A band
0.37	GO:0044430	cytoskeletal part
0.36	GO:0043234	protein complex
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.33

GO:0004674

sp|P02612|MLRM_CHICK
Myosin regulatory light chain 2, smooth muscle major isoform
Search

MYL9

0.94	Regulatory myosin light chain long version

0.44	GO:0072659	protein localization to plasma membrane
0.41	GO:0050793	regulation of developmental process
0.40	GO:0065008	regulation of biological quality
0.40	GO:0051128	regulation of cellular component organization
0.37	GO:0034109	homotypic cell-cell adhesion
0.37	GO:0050817	coagulation
0.37	GO:0042060	wound healing
0.37	GO:0001775	cell activation
0.36	GO:0031032	actomyosin structure organization
0.36	GO:0006936	muscle contraction

0.70	GO:0005509	calcium ion binding
0.46	GO:0035254	glutamate receptor binding
0.45	GO:0032036	myosin heavy chain binding
0.36	GO:0008307	structural constituent of muscle
0.35	GO:0045159	myosin II binding
0.35	GO:0030898	actin-dependent ATPase activity
0.34	GO:0051015	actin filament binding
0.34	GO:0019904	protein domain specific binding
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0051020	GTPase binding

0.51	GO:0016460	myosin II complex
0.50	GO:0097517	contractile actin filament bundle
0.50	GO:0042641	actomyosin
0.49	GO:0030018	Z disc
0.38	GO:0099738	cell cortex region
0.35	GO:0097513	myosin II filament
0.34	GO:0005829	cytosol
0.34	GO:0005903	brush border
0.34	GO:0070062	extracellular exosome
0.34	GO:0045177	apical part of cell

sp|P02640|VILI_CHICK
Villin-1
Search

VIL1

0.95

Adseverin

0.73	GO:0051014	actin filament severing
0.72	GO:0051693	actin filament capping
0.70	GO:0045010	actin nucleation
0.58	GO:0031346	positive regulation of cell projection organization
0.58	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.57	GO:0060327	cytoplasmic actin-based contraction involved in cell motility
0.56	GO:0051240	positive regulation of multicellular organismal process
0.56	GO:0035729	cellular response to hepatocyte growth factor stimulus
0.56	GO:1902896	terminal web assembly
0.56	GO:0001951	intestinal D-glucose absorption

0.78	GO:0051015	actin filament binding
0.74	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.62	GO:0005509	calcium ion binding
0.57	GO:0035727	lysophosphatidic acid binding
0.55	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.49	GO:0042803	protein homodimerization activity
0.33	GO:0016791	phosphatase activity

0.55	GO:0032433	filopodium tip
0.54	GO:0005902	microvillus
0.53	GO:0032432	actin filament bundle
0.53	GO:0001726	ruffle
0.52	GO:0030027	lamellipodium
0.52	GO:0005903	brush border
0.41	GO:0005886	plasma membrane
0.36	GO:0030424	axon
0.36	GO:0070062	extracellular exosome
0.34	GO:0005737	cytoplasm

0.33

EC:3.1.3 EC:3.1.3.41

GO:0016791

sp|P02642|TNNT2_CHICK
Troponin T, cardiac muscle isoforms
Search

TNNT2

0.95	Low Mr mutant cardiac troponin T

0.83	GO:0006937	regulation of muscle contraction
0.59	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.58	GO:0030049	muscle filament sliding
0.57	GO:0008016	regulation of heart contraction
0.56	GO:0060047	heart contraction
0.56	GO:0006941	striated muscle contraction
0.54	GO:0051592	response to calcium ion
0.53	GO:0032780	negative regulation of ATPase activity
0.52	GO:0032781	positive regulation of ATPase activity
0.47	GO:0097534	lymphoid lineage cell migration

0.58	GO:0030172	troponin C binding
0.57	GO:0031013	troponin I binding
0.55	GO:0005523	tropomyosin binding
0.49	GO:0003779	actin binding
0.36	GO:0030674	protein binding, bridging
0.35	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0016887	ATPase activity
0.32	GO:0046872	metal ion binding

0.84	GO:0005861	troponin complex
0.54	GO:0097512	cardiac myofibril
0.33	GO:0005829	cytosol

0.34

GO:0016887

sp|P02659|APOV1_CHICK
Apovitellenin-1
Search

0.97	Apovitellenin-1

0.72	GO:0043086	negative regulation of catalytic activity
0.63	GO:0006629	lipid metabolic process

0.76	GO:0045735	nutrient reservoir activity
0.74	GO:0004857	enzyme inhibitor activity

0.86	GO:0042627	chylomicron
0.83	GO:0034361	very-low-density lipoprotein particle
0.30	GO:0031224	intrinsic component of membrane

sp|P02701|AVID_CHICK
Avidin
Search

0.87

Avidin

0.54	GO:0019731	antibacterial humoral response
0.48	GO:0015878	biotin transport

0.59

GO:0009374

biotin binding

0.65	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|P02707|LECH_CHICK
Hepatic lectin
Search

0.91	Hepatic lectin

0.51	GO:0090238	positive regulation of arachidonic acid secretion
0.50	GO:0090403	oxidative stress-induced premature senescence
0.49	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator
0.49	GO:0090399	replicative senescence
0.48	GO:0001816	cytokine production
0.46	GO:0006897	endocytosis
0.44	GO:0072593	reactive oxygen species metabolic process
0.38	GO:0007154	cell communication
0.38	GO:0023052	signaling
0.37	GO:0002292	T cell differentiation involved in immune response

0.66	GO:0030246	carbohydrate binding
0.50	GO:0043274	phospholipase binding
0.41	GO:0004872	receptor activity
0.38	GO:0004871	signal transducer activity
0.36	GO:0043565	sequence-specific DNA binding
0.35	GO:0036094	small molecule binding
0.35	GO:0046872	metal ion binding
0.33	GO:0005216	ion channel activity
0.33	GO:0004252	serine-type endopeptidase activity

0.45	GO:0043235	receptor complex
0.44	GO:0009986	cell surface
0.39	GO:0005886	plasma membrane
0.36	GO:0005576	extracellular region
0.35	GO:0005634	nucleus
0.33	GO:0031982	vesicle
0.30	GO:0016021	integral component of membrane

0.33

GO:0004252

sp|P02713|ACHG_CHICK
Acetylcholine receptor subunit gamma
Search

CHRNG

0.91	Nicotinic acetylcholine receptor subunit epsilon

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.50	GO:0007271	synaptic transmission, cholinergic
0.48	GO:0035094	response to nicotine
0.48	GO:0007274	neuromuscular synaptic transmission
0.40	GO:0006936	muscle contraction
0.39	GO:0006812	cation transport
0.38	GO:0050881	musculoskeletal movement

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.49	GO:0042166	acetylcholine binding
0.35	GO:0005515	protein binding

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.49	GO:0005892	acetylcholine-gated channel complex

sp|P02717|ACHD_CHICK
Acetylcholine receptor subunit delta
Search

CHRND

0.91	Acetylcholine receptor subunit delta

0.78	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.50	GO:0007271	synaptic transmission, cholinergic
0.49	GO:0035094	response to nicotine
0.49	GO:0007274	neuromuscular synaptic transmission
0.47	GO:0048630	skeletal muscle tissue growth
0.46	GO:0050881	musculoskeletal movement
0.42	GO:0006936	muscle contraction
0.40	GO:0006812	cation transport
0.36	GO:0050905	neuromuscular process

0.81	GO:0022848	acetylcholine-gated cation-selective channel activity
0.69	GO:0099600	transmembrane receptor activity
0.52	GO:0042166	acetylcholine binding
0.36	GO:0004252	serine-type endopeptidase activity
0.35	GO:0005515	protein binding

0.77	GO:0045211	postsynaptic membrane
0.73	GO:0030054	cell junction
0.51	GO:0005892	acetylcholine-gated channel complex
0.41	GO:0005654	nucleoplasm
0.41	GO:0005829	cytosol

0.36

GO:0004252

sp|P02752|RBP_CHICK
Riboflavin-binding protein
Search

0.96

retbindin

0.76	GO:0032218	riboflavin transport
0.75	GO:1904656	regulation of sensory perception of sweet taste
0.75	GO:1904661	negative regulation of sensory perception of bitter taste

0.76	GO:0032217	riboflavin transmembrane transporter activity
0.71	GO:1902444	riboflavin binding

0.30	GO:0031224	intrinsic component of membrane
0.30	GO:0005623	cell

sp|P02789|TRFE_CHICK
Ovotransferrin
Search

0.76	Lactoferrin

0.86	GO:0019732	antifungal humoral response
0.85	GO:0019731	antibacterial humoral response
0.79	GO:0001817	regulation of cytokine production
0.61	GO:0006508	proteolysis
0.44	GO:1900229	negative regulation of single-species biofilm formation in or on host organism
0.44	GO:1902732	positive regulation of chondrocyte proliferation
0.44	GO:0044793	negative regulation by host of viral process
0.44	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway
0.44	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway
0.44	GO:0002227	innate immune response in mucosa

0.69	GO:0004252	serine-type endopeptidase activity
0.63	GO:0005506	iron ion binding
0.42	GO:0043539	protein serine/threonine kinase activator activity
0.42	GO:0008201	heparin binding
0.42	GO:0001530	lipopolysaccharide binding
0.42	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.41	GO:0016724	oxidoreductase activity, oxidizing metal ions, oxygen as acceptor

0.73	GO:0005615	extracellular space
0.43	GO:0042581	specific granule
0.40	GO:0009986	cell surface
0.38	GO:0044218	other organism cell membrane
0.37	GO:0043234	protein complex

0.69

GO:0004252

sp|P02822|OSTCN_CHICK
Osteocalcin
Search

BGLAP

0.97	Osteocalcin

0.85	GO:0030500	regulation of bone mineralization
0.64	GO:0033280	response to vitamin D
0.63	GO:0031214	biomineral tissue development
0.61	GO:0001649	osteoblast differentiation
0.39	GO:0033594	response to hydroxyisoflavone
0.38	GO:0032571	response to vitamin K
0.38	GO:0033574	response to testosterone
0.38	GO:0071295	cellular response to vitamin
0.38	GO:0014823	response to activity
0.38	GO:0045124	regulation of bone resorption

0.70	GO:0005509	calcium ion binding
0.39	GO:0008147	structural constituent of bone
0.39	GO:0046848	hydroxyapatite binding
0.35	GO:0042803	protein homodimerization activity
0.33	GO:0046914	transition metal ion binding

0.66	GO:0005576	extracellular region
0.44	GO:0005737	cytoplasm
0.37	GO:0043204	perikaryon
0.37	GO:0030425	dendrite
0.36	GO:0031982	vesicle
0.35	GO:0012505	endomembrane system
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0043231	intracellular membrane-bounded organelle

sp|P02845|VIT2_CHICK
Vitellogenin-2
Search

VTG2

0.53	Vitellogenin

0.74	GO:0006869	lipid transport
0.32	GO:0000398	mRNA splicing, via spliceosome
0.32	GO:1903165	response to polycyclic arene
0.32	GO:0032355	response to estradiol
0.32	GO:0032868	response to insulin
0.32	GO:0034605	cellular response to heat
0.31	GO:0006265	DNA topological change
0.31	GO:0065007	biological regulation
0.31	GO:0023052	signaling
0.31	GO:0007154	cell communication

0.76	GO:0005319	lipid transporter activity
0.42	GO:0045735	nutrient reservoir activity
0.32	GO:0003917	DNA topoisomerase type I activity
0.31	GO:0005102	receptor binding
0.31	GO:0004871	signal transducer activity
0.31	GO:0003677	DNA binding

0.32	GO:0005869	dynactin complex
0.32	GO:0060417	yolk
0.31	GO:0005615	extracellular space
0.31	GO:0005694	chromosome
0.31	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.32

EC:5.99.1.2

GO:0003917

sp|P04047|KITH_CHICK
Thymidine kinase, cytosolic
Search

TK1

0.51	Thymidine kinase, cytosolic

0.76	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process
0.67	GO:0071897	DNA biosynthetic process
0.57	GO:0016310	phosphorylation
0.54	GO:0051289	protein homotetramerization
0.47	GO:0046104	thymidine metabolic process
0.35	GO:0060138	fetal process involved in parturition
0.34	GO:0009165	nucleotide biosynthetic process
0.34	GO:0014856	skeletal muscle cell proliferation
0.34	GO:0043097	pyrimidine nucleoside salvage
0.34	GO:0051414	response to cortisol

0.81	GO:0004797	thymidine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0042802	identical protein binding
0.45	GO:0008270	zinc ion binding

0.35

GO:0005829

cytosol

0.81

EC:2.7.1.21

GO:0004797

sp|P04210|LV1_CHICK
Ig lambda chain V-1 region
Search

0.94	Ig lambda chain V-1 region

0.85

GO:0006958

complement activation, classical pathway

0.85

GO:0003823

antigen binding

0.66

GO:0005576

extracellular region

sp|P04268|TPM1_CHICK
Tropomyosin alpha-1 chain
Search

TPM1

0.75	Japanese quail alpha-tropomyosin

0.73	GO:0060048	cardiac muscle contraction
0.66	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.65	GO:1904753	negative regulation of vascular associated smooth muscle cell migration
0.64	GO:0097435	supramolecular fiber organization
0.64	GO:0030036	actin cytoskeleton organization
0.64	GO:1904706	negative regulation of vascular smooth muscle cell proliferation
0.60	GO:0055002	striated muscle cell development
0.59	GO:0010927	cellular component assembly involved in morphogenesis
0.57	GO:0003065	positive regulation of heart rate by epinephrine
0.56	GO:0034614	cellular response to reactive oxygen species

0.68	GO:0008092	cytoskeletal protein binding
0.68	GO:0008307	structural constituent of muscle
0.66	GO:0032403	protein complex binding
0.60	GO:0042803	protein homodimerization activity
0.59	GO:0046982	protein heterodimerization activity
0.46	GO:0097718	disordered domain specific binding
0.44	GO:0005200	structural constituent of cytoskeleton
0.41	GO:0047485	protein N-terminus binding

0.72	GO:0015629	actin cytoskeleton
0.65	GO:0032059	bleb
0.65	GO:0036379	myofilament
0.63	GO:0030017	sarcomere
0.63	GO:0044430	cytoskeletal part
0.61	GO:0032587	ruffle membrane
0.54	GO:0005829	cytosol
0.43	GO:0097512	cardiac myofibril
0.40	GO:0043234	protein complex

sp|P04354|CALB1_CHICK
Calbindin
Search

CALB1

0.96	Cerebellar calbindin

0.76	GO:0055074	calcium ion homeostasis
0.62	GO:0072027	connecting tubule development
0.61	GO:0072221	metanephric distal convoluted tubule development
0.61	GO:0035502	metanephric part of ureteric bud development
0.60	GO:0072205	metanephric collecting duct development
0.60	GO:0007614	short-term memory
0.59	GO:1900271	regulation of long-term synaptic potentiation
0.58	GO:0007616	long-term memory
0.58	GO:0010842	retina layer formation
0.55	GO:0007626	locomotory behavior

0.70	GO:0005509	calcium ion binding
0.47	GO:0008270	zinc ion binding
0.43	GO:0005499	vitamin D binding
0.33	GO:0005515	protein binding

0.56	GO:0043025	neuronal cell body
0.55	GO:0030425	dendrite
0.55	GO:0030424	axon
0.53	GO:0045202	synapse
0.50	GO:0005829	cytosol
0.46	GO:0005634	nucleus
0.39	GO:0044306	neuron projection terminus
0.38	GO:0044309	neuron spine
0.36	GO:0031982	vesicle
0.36	GO:0043230	extracellular organelle

sp|P04458|KRFB_CHICK
Feather keratin 2
Search

0.82	Feather beta keratin

0.71

GO:0007010

cytoskeleton organization

0.77

GO:0005200

structural constituent of cytoskeleton

0.79

GO:0005882

intermediate filament

sp|P04459|KRSC_CHICK
Scale keratin
Search

0.69	Scale keratin

0.71

GO:0007010

cytoskeleton organization

0.77

GO:0005200

structural constituent of cytoskeleton

0.79

GO:0005882

intermediate filament

sp|P04625|THA_CHICK
Thyroid hormone receptor alpha
Search

THRA

0.93	Thyroid hormone receptor alpha variant a

0.78	GO:0030522	intracellular receptor signaling pathway
0.77	GO:0043401	steroid hormone mediated signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0008050	female courtship behavior
0.52	GO:0060509	Type I pneumocyte differentiation
0.51	GO:0045925	positive regulation of female receptivity
0.50	GO:0002155	regulation of thyroid hormone mediated signaling pathway

0.84	GO:0004887	thyroid hormone receptor activity
0.79	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.57	GO:0070324	thyroid hormone binding
0.52	GO:0002153	steroid receptor RNA activator RNA binding
0.49	GO:0031490	chromatin DNA binding
0.47	GO:0017025	TBP-class protein binding
0.46	GO:0019904	protein domain specific binding
0.45	GO:0044212	transcription regulatory region DNA binding

0.60	GO:0005634	nucleus
0.43	GO:0005829	cytosol
0.36	GO:0043233	organelle lumen
0.36	GO:0000785	chromatin
0.33	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

sp|P05081|KAD1_CHICK
Adenylate kinase isoenzyme 1
Search

AK1

0.91	Adenylate kinase isoenzyme 1

0.78	GO:0006172	ADP biosynthetic process
0.68	GO:0046033	AMP metabolic process
0.66	GO:0046939	nucleotide phosphorylation
0.65	GO:0009142	nucleoside triphosphate biosynthetic process
0.60	GO:0046034	ATP metabolic process
0.52	GO:0007050	cell cycle arrest
0.38	GO:0097503	sialylation
0.37	GO:0033993	response to lipid
0.37	GO:0006486	protein glycosylation
0.36	GO:1901700	response to oxygen-containing compound

0.74	GO:0004017	adenylate kinase activity
0.74	GO:0004550	nucleoside diphosphate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008373	sialyltransferase activity
0.35	GO:0030695	GTPase regulator activity

0.54	GO:0001520	outer dense fiber
0.47	GO:0005737	cytoplasm
0.41	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0043005	neuron projection
0.30	GO:0031224	intrinsic component of membrane

0.74

EC:2.7.4.3

GO:0004017

sp|P05083|ARLY2_CHICK
Argininosuccinate lyase
Search

ASL

0.43	Argininosuccinate lyase

0.77	GO:0042450	arginine biosynthetic process via ornithine
0.51	GO:0019676	ammonia assimilation cycle
0.48	GO:0007626	locomotory behavior
0.47	GO:0009791	post-embryonic development
0.41	GO:0000050	urea cycle
0.35	GO:0000053	argininosuccinate metabolic process
0.35	GO:0060539	diaphragm development
0.35	GO:0071377	cellular response to glucagon stimulus
0.35	GO:0007494	midgut development
0.35	GO:0071549	cellular response to dexamethasone stimulus

0.79	GO:0004056	argininosuccinate lyase activity
0.43	GO:0005212	structural constituent of eye lens
0.36	GO:0042802	identical protein binding
0.32	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0003723	RNA binding
0.32	GO:0004333	fumarate hydratase activity
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.37	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0070852	cell body fiber
0.35	GO:0043204	perikaryon
0.34	GO:0031968	organelle outer membrane
0.33	GO:0012505	endomembrane system
0.33	GO:0005634	nucleus

0.79	EC:4.3.2.1	GO:0004056
0.32	KEGG:R01082	GO:0004333

sp|P05094|ACTN1_CHICK
Alpha-actinin-1
Search

ACTN1

0.89	Alpha-actinin-1

0.86	GO:0051764	actin crosslink formation
0.83	GO:0051017	actin filament bundle assembly
0.69	GO:0048741	skeletal muscle fiber development
0.68	GO:0045214	sarcomere organization
0.51	GO:0051639	actin filament network formation
0.51	GO:0048041	focal adhesion assembly
0.51	GO:0030220	platelet formation
0.48	GO:0051271	negative regulation of cellular component movement
0.40	GO:2001141	regulation of RNA biosynthetic process
0.37	GO:0070527	platelet aggregation

0.78	GO:0051015	actin filament binding
0.73	GO:0017166	vinculin binding
0.70	GO:0051393	alpha-actinin binding
0.70	GO:0005509	calcium ion binding
0.63	GO:0042803	protein homodimerization activity
0.50	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.50	GO:0044325	ion channel binding
0.49	GO:0005178	integrin binding
0.47	GO:0003725	double-stranded RNA binding
0.35	GO:0019904	protein domain specific binding

0.73	GO:0030486	smooth muscle dense body
0.73	GO:0090637	inner dense plaque of desmosome
0.73	GO:0090636	outer dense plaque of desmosome
0.72	GO:1990357	terminal web
0.71	GO:0005915	zonula adherens
0.71	GO:0097433	dense body
0.70	GO:0097517	contractile actin filament bundle
0.70	GO:0042641	actomyosin
0.68	GO:0016328	lateral plasma membrane
0.67	GO:0042383	sarcolemma

sp|P05099|MATN1_CHICK
Cartilage matrix protein
Search

MATN1

0.90	cartilage matrix protein isoform X1

0.58	GO:0003429	growth plate cartilage chondrocyte morphogenesis
0.53	GO:0030500	regulation of bone mineralization
0.38	GO:0031104	dendrite regeneration
0.37	GO:1901031	regulation of response to reactive oxygen species
0.37	GO:0048678	response to axon injury
0.37	GO:0008347	glial cell migration
0.37	GO:0001764	neuron migration
0.36	GO:0007411	axon guidance
0.35	GO:0030198	extracellular matrix organization
0.34	GO:0006461	protein complex assembly

0.78	GO:0005201	extracellular matrix structural constituent
0.69	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.33	GO:0003677	DNA binding
0.32	GO:0000287	magnesium ion binding

0.73	GO:0005578	proteinaceous extracellular matrix
0.36	GO:0044420	extracellular matrix component
0.35	GO:0005615	extracellular space
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P05122|KCRB_CHICK
Creatine kinase B-type
Search

CKB

0.91	Brain-subtype creatine kinase

0.57	GO:0016310	phosphorylation
0.44	GO:0030644	cellular chloride ion homeostasis
0.43	GO:0046314	phosphocreatine biosynthetic process
0.41	GO:0007420	brain development
0.39	GO:0009408	response to heat
0.37	GO:0048857	neural nucleus development
0.37	GO:0006600	creatine metabolic process
0.34	GO:0006754	ATP biosynthetic process

0.61	GO:0004111	creatine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0031625	ubiquitin protein ligase binding

0.50	GO:0043209	myelin sheath
0.49	GO:0005615	extracellular space
0.45	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.38	GO:0043025	neuronal cell body
0.38	GO:0030425	dendrite
0.37	GO:0043230	extracellular organelle
0.35	GO:0005634	nucleus
0.35	GO:0031982	vesicle

0.61	EC:2.7.3.2	GO:0004111
0.61	KEGG:R01881	GO:0004111

sp|P05153|PCKGC_CHICK
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
Search

PCK1

0.97	Phosphoenolpyruvate carboxykinase, cytosolic

0.72	GO:0019319	hexose biosynthetic process
0.70	GO:0006006	glucose metabolic process
0.58	GO:0046327	glycerol biosynthetic process from pyruvate
0.57	GO:0061402	positive regulation of transcription from RNA polymerase II promoter in response to acidic pH
0.57	GO:0051365	cellular response to potassium ion starvation
0.54	GO:0032868	response to insulin
0.52	GO:0016310	phosphorylation
0.51	GO:0006475	internal protein amino acid acetylation
0.46	GO:0009746	response to hexose
0.43	GO:0048878	chemical homeostasis

0.81	GO:0004613	phosphoenolpyruvate carboxykinase (GTP) activity
0.65	GO:0005525	GTP binding
0.54	GO:0016301	kinase activity
0.49	GO:0030145	manganese ion binding
0.48	GO:0043177	organic acid binding
0.45	GO:0000287	magnesium ion binding
0.38	GO:0019003	GDP binding
0.36	GO:0019157	malate oxidase activity
0.35	GO:0050692	DBD domain binding
0.35	GO:0051379	epinephrine binding

0.47	GO:0005829	cytosol
0.37	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome

0.81	EC:4.1.1.32	GO:0004613
0.36	KEGG:R00360	GO:0019157

sp|P05180|CP2H1_CHICK
Cytochrome P450 2H1
Search

CYP2C8

0.97	Cytochrome P450 family 2 subfamily C member 8

0.53	GO:0019373	epoxygenase P450 pathway
0.53	GO:0055114	oxidation-reduction process
0.43	GO:0042738	exogenous drug catabolic process
0.42	GO:0002933	lipid hydroxylation
0.41	GO:0070988	demethylation
0.40	GO:0008202	steroid metabolic process
0.36	GO:0043651	linoleic acid metabolic process
0.36	GO:0006805	xenobiotic metabolic process
0.35	GO:0097267	omega-hydroxylase P450 pathway
0.35	GO:0016098	monoterpenoid metabolic process

0.70	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.54	GO:0008392	arachidonic acid epoxygenase activity
0.53	GO:0008395	steroid hydroxylase activity
0.44	GO:0034875	caffeine oxidase activity
0.37	GO:0071614	linoleic acid epoxygenase activity
0.36	GO:0019825	oxygen binding
0.35	GO:0008389	coumarin 7-hydroxylase activity
0.33	GO:0008270	zinc ion binding

0.42	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.70

EC:1.14.14

GO:0016712

sp|P05200|NGF_CHICK
Beta-nerve growth factor
Search

NGF

0.74	Beta-nerve growth factor

0.75	GO:0010469	regulation of receptor activity
0.38	GO:0048812	neuron projection morphogenesis
0.38	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors
0.36	GO:0010951	negative regulation of endopeptidase activity
0.36	GO:0010628	positive regulation of gene expression
0.35	GO:0043524	negative regulation of neuron apoptotic process
0.35	GO:0045664	regulation of neuron differentiation
0.35	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.34	GO:0007267	cell-cell signaling

0.78	GO:0008083	growth factor activity
0.41	GO:0005163	nerve growth factor receptor binding
0.38	GO:0008191	metalloendopeptidase inhibitor activity

0.34	GO:0031410	cytoplasmic vesicle
0.34	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|P05300|LAMP1_CHICK
Lysosome-associated membrane glycoprotein 1
Search

LAMP1

0.94	Lysosomal-associated membrane glycoprotein 1

0.54	GO:0043323	positive regulation of natural killer cell degranulation
0.53	GO:1902513	regulation of organelle transport along microtubule
0.53	GO:0008626	granzyme-mediated apoptotic signaling pathway
0.53	GO:0090160	Golgi to lysosome transport
0.49	GO:0050821	protein stabilization
0.46	GO:0072594	establishment of protein localization to organelle
0.39	GO:0048102	autophagic cell death
0.35	GO:0043312	neutrophil degranulation
0.33	GO:0051704	multi-organism process
0.33	GO:0048609	multicellular organismal reproductive process

0.48	GO:0019904	protein domain specific binding
0.45	GO:0019899	enzyme binding
0.35	GO:0104005	hijacked molecular function

0.82	GO:0005765	lysosomal membrane
0.53	GO:0044194	cytolytic granule
0.53	GO:0032010	phagolysosome
0.52	GO:0044754	autolysosome
0.52	GO:0030670	phagocytic vesicle membrane
0.51	GO:0005771	multivesicular body
0.51	GO:0042470	melanosome
0.51	GO:0042383	sarcolemma
0.49	GO:0008021	synaptic vesicle
0.49	GO:0009897	external side of plasma membrane

sp|P05419|CALN_CHICK
Neo-calmodulin (Fragment)
Search

0.50	Calmodulin like 5

0.40	GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity
0.39	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity
0.39	GO:0005513	detection of calcium ion
0.39	GO:0032516	positive regulation of phosphoprotein phosphatase activity
0.39	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.39	GO:0030819	positive regulation of cAMP biosynthetic process
0.38	GO:0055117	regulation of cardiac muscle contraction
0.38	GO:0002027	regulation of heart rate
0.38	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
0.37	GO:0043388	positive regulation of DNA binding

0.70	GO:0005509	calcium ion binding
0.40	GO:0031997	N-terminal myristoylation domain binding
0.39	GO:0019211	phosphatase activator activity
0.39	GO:0031432	titin binding
0.39	GO:0008179	adenylate cyclase binding
0.39	GO:0097718	disordered domain specific binding
0.38	GO:0044325	ion channel binding
0.38	GO:0019855	calcium channel inhibitor activity
0.38	GO:0019888	protein phosphatase regulator activity
0.37	GO:0019901	protein kinase binding

0.38	GO:0034703	cation channel complex
0.38	GO:0005876	spindle microtubule
0.38	GO:0030017	sarcomere
0.37	GO:0000922	spindle pole
0.37	GO:0005813	centrosome
0.37	GO:0043209	myelin sheath
0.35	GO:0005887	integral component of plasma membrane
0.35	GO:1902494	catalytic complex
0.35	GO:0043234	protein complex
0.33	GO:0005829	cytosol

sp|P05625|RAF1_CHICK
RAF proto-oncogene serine/threonine-protein kinase
Search

RAF1

0.92	RAF proto-oncogene serine/threonine-protein kinase

0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.48	GO:0000186	activation of MAPKK activity
0.48	GO:0071550	death-inducing signaling complex assembly
0.47	GO:0035773	insulin secretion involved in cellular response to glucose stimulus
0.46	GO:0035994	response to muscle stretch
0.46	GO:0043066	negative regulation of apoptotic process
0.46	GO:0048011	neurotrophin TRK receptor signaling pathway
0.46	GO:0007190	activation of adenylate cyclase activity
0.46	GO:0030878	thyroid gland development

0.77	GO:0005057	signal transducer activity, downstream of receptor
0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.47	GO:0031434	mitogen-activated protein kinase kinase binding
0.44	GO:0010856	adenylate cyclase activator activity
0.42	GO:0031267	small GTPase binding

0.46	GO:0031143	pseudopodium
0.45	GO:0005622	intracellular
0.40	GO:0012505	endomembrane system
0.40	GO:0031974	membrane-enclosed lumen
0.39	GO:0005886	plasma membrane
0.38	GO:0043227	membrane-bounded organelle
0.38	GO:0044422	organelle part
0.35	GO:0098805	whole membrane
0.35	GO:0019867	outer membrane
0.34	GO:0031975	envelope

0.69

GO:0004674

sp|P06212|ESR1_CHICK
Estrogen receptor
Search

ESR1

0.93	Estrogen receptor

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.59	GO:0060523	prostate epithelial cord elongation
0.59	GO:0071392	cellular response to estradiol stimulus
0.58	GO:0001547	antral ovarian follicle growth
0.58	GO:0060526	prostate glandular acinus morphogenesis
0.58	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA
0.58	GO:0060687	regulation of branching involved in prostate gland morphogenesis
0.58	GO:0006351	transcription, DNA-templated
0.58	GO:0060068	vagina development
0.57	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling

0.85	GO:0030284	estrogen receptor activity
0.81	GO:0005496	steroid binding
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.59	GO:0001093	TFIIB-class transcription factor binding
0.57	GO:0001223	transcription coactivator binding
0.57	GO:0030331	estrogen receptor binding
0.56	GO:0051117	ATPase binding
0.54	GO:0008013	beta-catenin binding

0.61	GO:0005634	nucleus
0.57	GO:0097550	transcriptional preinitiation complex
0.55	GO:0035327	transcriptionally active chromatin
0.47	GO:0070013	intracellular organelle lumen
0.44	GO:0043234	protein complex
0.42	GO:0005886	plasma membrane
0.39	GO:0005737	cytoplasm
0.38	GO:0012505	endomembrane system
0.35	GO:0043204	perikaryon
0.35	GO:0043195	terminal bouton

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

sp|P07031|ACYP2_CHICK
Acylphosphatase-2
Search

ACYP2

0.50	Acylphosphatase

0.45	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.44	GO:0018108	peptidyl-tyrosine phosphorylation
0.34	GO:0051693	actin filament capping
0.33	GO:0007010	cytoskeleton organization
0.32	GO:0006261	DNA-dependent DNA replication
0.32	GO:0071897	DNA biosynthetic process
0.32	GO:0006281	DNA repair

0.81	GO:0003998	acylphosphatase activity
0.46	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0042802	identical protein binding
0.34	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0005543	phospholipid binding
0.33	GO:0003779	actin binding
0.32	GO:0003684	damaged DNA binding

0.42	GO:0005739	mitochondrion
0.34	GO:0008091	spectrin
0.30	GO:0016020	membrane

0.81

EC:3.6.1.7

GO:0003998

sp|P07032|ACYP1_CHICK
Acylphosphatase-1
Search

ACYP1

0.54	Acylphosphatase

0.35	GO:0007131	reciprocal meiotic recombination
0.35	GO:0006298	mismatch repair
0.33	GO:0046944	protein carbamoylation
0.32	GO:0010469	regulation of receptor activity
0.32	GO:0016310	phosphorylation

0.81	GO:0003998	acylphosphatase activity
0.34	GO:0030983	mismatched DNA binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003725	double-stranded RNA binding
0.33	GO:0016743	carboxyl- or carbamoyltransferase activity
0.33	GO:0008083	growth factor activity
0.32	GO:0016301	kinase activity
0.32	GO:0008270	zinc ion binding

0.35	GO:0032300	mismatch repair complex
0.34	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.81

EC:3.6.1.7

GO:0003998

sp|P07090|CALB2_CHICK
Calretinin
Search

CALB2

0.94	Testicular secretory protein Li 8

0.59	GO:0055074	calcium ion homeostasis
0.46	GO:0072503	cellular divalent inorganic cation homeostasis
0.45	GO:0072027	connecting tubule development
0.45	GO:0072221	metanephric distal convoluted tubule development
0.45	GO:0035502	metanephric part of ureteric bud development
0.44	GO:0072205	metanephric collecting duct development
0.44	GO:0007614	short-term memory
0.44	GO:0006875	cellular metal ion homeostasis
0.44	GO:1900271	regulation of long-term synaptic potentiation
0.43	GO:0007616	long-term memory

0.70	GO:0005509	calcium ion binding
0.38	GO:0008270	zinc ion binding
0.34	GO:0005499	vitamin D binding

0.50	GO:0005921	gap junction
0.50	GO:0005829	cytosol
0.48	GO:0043005	neuron projection
0.47	GO:0045202	synapse
0.43	GO:0120038	plasma membrane bounded cell projection part
0.42	GO:0043025	neuronal cell body
0.42	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P07228|ITB1_CHICK
Integrin beta-1
Search

ITGB1

0.67	Integrin beta

0.82	GO:0007160	cell-matrix adhesion
0.80	GO:0007229	integrin-mediated signaling pathway
0.58	GO:0010710	regulation of collagen catabolic process
0.57	GO:0033627	cell adhesion mediated by integrin
0.56	GO:0071404	cellular response to low-density lipoprotein particle stimulus
0.55	GO:1903078	positive regulation of protein localization to plasma membrane
0.55	GO:0021943	formation of radial glial scaffolds
0.55	GO:2000811	negative regulation of anoikis
0.54	GO:0050901	leukocyte tethering or rolling
0.54	GO:0031623	receptor internalization

0.65	GO:0004872	receptor activity
0.57	GO:0001968	fibronectin binding
0.56	GO:0019960	C-X3-C chemokine binding
0.56	GO:0098639	collagen binding involved in cell-matrix adhesion
0.52	GO:0043236	laminin binding
0.52	GO:0002020	protease binding
0.52	GO:0046982	protein heterodimerization activity
0.51	GO:0005178	integrin binding
0.51	GO:0045296	cadherin binding
0.48	GO:0003779	actin binding

0.81	GO:0008305	integrin complex
0.58	GO:0071438	invadopodium membrane
0.56	GO:0032587	ruffle membrane
0.54	GO:0035748	myelin sheath abaxonal region
0.53	GO:0005925	focal adhesion
0.53	GO:0042383	sarcolemma
0.53	GO:0031594	neuromuscular junction
0.52	GO:0030175	filopodium
0.52	GO:0014704	intercalated disc
0.51	GO:0009986	cell surface

sp|P07322|ENOB_CHICK
Beta-enolase
Search

ENO3

0.68	Beta-enolase 3 transcript variant 1

0.71	GO:0006096	glycolytic process
0.46	GO:0061718	glucose catabolic process to pyruvate
0.46	GO:0006735	NADH regeneration
0.46	GO:1903297	regulation of hypoxia-induced intrinsic apoptotic signaling pathway
0.46	GO:0010756	positive regulation of plasminogen activation
0.46	GO:2001171	positive regulation of ATP biosynthetic process
0.45	GO:1900038	negative regulation of cellular response to hypoxia
0.45	GO:0045933	positive regulation of muscle contraction
0.44	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.44	GO:0030308	negative regulation of cell growth

0.78	GO:0004634	phosphopyruvate hydratase activity
0.64	GO:0000287	magnesium ion binding
0.44	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.43	GO:0045296	cadherin binding
0.43	GO:0042803	protein homodimerization activity
0.42	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.41	GO:0051020	GTPase binding
0.36	GO:0046982	protein heterodimerization activity
0.34	GO:0005212	structural constituent of eye lens
0.33	GO:0003723	RNA binding

0.77	GO:0000015	phosphopyruvate hydratase complex
0.43	GO:0099738	cell cortex region
0.43	GO:0005886	plasma membrane
0.42	GO:0009986	cell surface
0.41	GO:0001917	photoreceptor inner segment
0.41	GO:0043204	perikaryon
0.40	GO:0043209	myelin sheath
0.37	GO:0070062	extracellular exosome
0.35	GO:0031430	M band
0.34	GO:0000145	exocyst

0.78

EC:4.2.1.11

GO:0004634

sp|P07341|ALDOB_CHICK
Fructose-bisphosphate aldolase B
Search

ALDOB

0.50	Fructose-bisphosphate aldolase B

0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.49	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly
0.49	GO:0030388	fructose 1,6-bisphosphate metabolic process
0.49	GO:0006000	fructose metabolic process
0.48	GO:0032781	positive regulation of ATPase activity
0.38	GO:0055114	oxidation-reduction process
0.35	GO:0001889	liver development

0.79	GO:0004332	fructose-bisphosphate aldolase activity
0.54	GO:0061609	fructose-1-phosphate aldolase activity
0.53	GO:0070061	fructose binding
0.50	GO:0051117	ATPase binding
0.46	GO:0042802	identical protein binding
0.45	GO:0008092	cytoskeletal protein binding

0.51	GO:0034451	centriolar satellite
0.35	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.79

EC:4.1.2.13

GO:0004332

sp|P07354|HPLN1_CHICK
Hyaluronan and proteoglycan link protein 1
Search

HAPLN1

0.97	Hyaluronan and proteoglycan link protein 1

0.71	GO:0007155	cell adhesion
0.48	GO:0001501	skeletal system development
0.47	GO:0007417	central nervous system development
0.40	GO:0031101	fin regeneration
0.35	GO:0002040	sprouting angiogenesis
0.35	GO:0030198	extracellular matrix organization

0.83	GO:0005540	hyaluronic acid binding
0.48	GO:0005201	extracellular matrix structural constituent

0.53	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

sp|P07530|CRBB1_CHICK
Beta-crystallin B1
Search

CRYBB1

0.71	Acyl-CoA dehydrogenase, C-2 to C-3 short chain

0.76	GO:0007601	visual perception
0.35	GO:0006478	peptidyl-tyrosine sulfation
0.35	GO:0043010	camera-type eye development
0.32	GO:0055114	oxidation-reduction process

0.83	GO:0005212	structural constituent of eye lens
0.35	GO:0008476	protein-tyrosine sulfotransferase activity
0.35	GO:0005515	protein binding
0.34	GO:0003995	acyl-CoA dehydrogenase activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.30

GO:0031224

intrinsic component of membrane

0.35

EC:2.8.2.20

GO:0008476

sp|P07583|LEG4_CHICK
Beta-galactoside-binding lectin
Search

LGALS1

0.66	Beta-galactoside-binding lectin

0.51	GO:0002317	plasma cell differentiation
0.50	GO:0046598	positive regulation of viral entry into host cell
0.49	GO:0031295	T cell costimulation
0.49	GO:0045445	myoblast differentiation
0.38	GO:0050767	regulation of neurogenesis
0.38	GO:0045597	positive regulation of cell differentiation
0.38	GO:0034120	positive regulation of erythrocyte aggregation
0.38	GO:0002040	sprouting angiogenesis
0.38	GO:0051240	positive regulation of multicellular organismal process
0.38	GO:0035900	response to isolation stress

0.70	GO:0030246	carbohydrate binding
0.40	GO:0043236	laminin binding
0.38	GO:0016936	galactoside binding
0.35	GO:0042803	protein homodimerization activity
0.34	GO:0004871	signal transducer activity
0.34	GO:0003723	RNA binding

0.45	GO:0031012	extracellular matrix
0.44	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:0009986	cell surface
0.35	GO:0005622	intracellular
0.33	GO:0012505	endomembrane system
0.33	GO:0043233	organelle lumen
0.30	GO:0016020	membrane

sp|P07630|CAH2_CHICK
Carbonic anhydrase 2
Search

CA2

0.86	Carbonic anhydrase II

0.71	GO:0006730	one-carbon metabolic process
0.55	GO:0044070	regulation of anion transport
0.54	GO:0038166	angiotensin-activated signaling pathway
0.54	GO:0032849	positive regulation of cellular pH reduction
0.54	GO:2000878	positive regulation of oligopeptide transport
0.54	GO:2001148	regulation of dipeptide transmembrane transport
0.53	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.51	GO:0015670	carbon dioxide transport
0.49	GO:0034764	positive regulation of transmembrane transport
0.46	GO:0002009	morphogenesis of an epithelium

0.77	GO:0004089	carbonate dehydratase activity
0.63	GO:0008270	zinc ion binding
0.55	GO:0004064	arylesterase activity
0.40	GO:0016151	nickel cation binding
0.34	GO:0005515	protein binding
0.33	GO:0016791	phosphatase activity

0.51	GO:0045177	apical part of cell
0.48	GO:0043209	myelin sheath
0.47	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.38	GO:0005902	microvillus
0.38	GO:0030424	axon
0.37	GO:0005615	extracellular space
0.36	GO:0043227	membrane-bounded organelle
0.36	GO:0043230	extracellular organelle
0.35	GO:0043229	intracellular organelle

0.77

EC:4.2.1.1

GO:0004089

sp|P07660|CALC_CHICK
Calcitonin
Search

CALCA

0.96	Salmon calcitonin-IV

0.76	GO:0010469	regulation of receptor activity
0.46	GO:0055074	calcium ion homeostasis
0.44	GO:0045779	negative regulation of bone resorption
0.44	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.44	GO:0002548	monocyte chemotaxis
0.43	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.43	GO:0072503	cellular divalent inorganic cation homeostasis
0.42	GO:0032147	activation of protein kinase activity
0.41	GO:0006875	cellular metal ion homeostasis
0.40	GO:0045892	negative regulation of transcription, DNA-templated

0.79	GO:0005179	hormone activity
0.47	GO:0031716	calcitonin receptor binding
0.40	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.34	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|P07751|SPTN1_CHICK
Spectrin alpha chain, non-erythrocytic 1
Search

SPTAN1

0.62	Spectrin alpha chain, non-erythrocytic 1

0.42	GO:0045162	clustering of voltage-gated sodium channels
0.39	GO:0051693	actin filament capping
0.39	GO:0016973	poly(A)+ mRNA export from nucleus
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0007010	cytoskeleton organization
0.35	GO:0007411	axon guidance
0.35	GO:0000165	MAPK cascade
0.35	GO:0006888	ER to Golgi vesicle-mediated transport
0.34	GO:0030029	actin filament-based process
0.34	GO:0065009	regulation of molecular function

0.70	GO:0005509	calcium ion binding
0.50	GO:0045296	cadherin binding
0.39	GO:0005516	calmodulin binding
0.38	GO:0003779	actin binding
0.37	GO:0030507	spectrin binding
0.36	GO:0046982	protein heterodimerization activity
0.35	GO:0047485	protein N-terminus binding
0.35	GO:0019905	syntaxin binding
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0005200	structural constituent of cytoskeleton

0.46	GO:0015630	microtubule cytoskeleton
0.44	GO:0033270	paranode region of axon
0.42	GO:0033268	node of Ranvier
0.41	GO:0043227	membrane-bounded organelle
0.39	GO:0044449	contractile fiber part
0.39	GO:0030016	myofibril
0.38	GO:0005938	cell cortex
0.38	GO:0005916	fascia adherens
0.37	GO:0016328	lateral plasma membrane
0.37	GO:0012505	endomembrane system

sp|P07812|PRGR_CHICK
Progesterone receptor
Search

PGR

0.69	Progesterone receptor PR

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:0030728	ovulation
0.43	GO:0042700	luteinizing hormone signaling pathway
0.42	GO:0038001	paracrine signaling
0.41	GO:0002070	epithelial cell maturation
0.41	GO:0048286	lung alveolus development

0.79	GO:0003707	steroid hormone receptor activity
0.63	GO:0005496	steroid binding
0.62	GO:0043565	sequence-specific DNA binding
0.61	GO:0008270	zinc ion binding
0.59	GO:0003700	DNA binding transcription factor activity
0.41	GO:0051117	ATPase binding
0.39	GO:0001012	RNA polymerase II regulatory region DNA binding
0.39	GO:0051879	Hsp90 protein binding
0.39	GO:0030544	Hsp70 protein binding
0.39	GO:0042562	hormone binding

0.61	GO:0005634	nucleus
0.38	GO:0043235	receptor complex
0.37	GO:0000785	chromatin
0.37	GO:0032993	protein-DNA complex
0.36	GO:0005829	cytosol
0.36	GO:0031974	membrane-enclosed lumen

sp|P07850|SUOX_CHICK
Sulfite oxidase
Search

SUOX

0.69	Mitochondrial sulfite oxidase

0.76	GO:0042128	nitrate assimilation
0.53	GO:0055114	oxidation-reduction process
0.37	GO:0006790	sulfur compound metabolic process
0.34	GO:0007584	response to nutrient
0.33	GO:0042254	ribosome biogenesis
0.33	GO:0005975	carbohydrate metabolic process

0.76	GO:0030151	molybdenum ion binding
0.61	GO:0020037	heme binding
0.57	GO:0043546	molybdopterin cofactor binding
0.54	GO:0016491	oxidoreductase activity
0.35	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.43	GO:0005739	mitochondrion
0.39	GO:0031970	organelle envelope lumen
0.33	GO:0005829	cytosol
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.54

EC:1

GO:0016491

sp|P07898|PGCA_CHICK
Aggrecan core protein
Search

ACAN

0.92	Aggrecan core protein isoform A

0.72	GO:0007155	cell adhesion
0.54	GO:0001502	cartilage condensation
0.53	GO:0002063	chondrocyte development
0.53	GO:0030199	collagen fibril organization
0.52	GO:0030166	proteoglycan biosynthetic process
0.50	GO:0007507	heart development
0.44	GO:0007417	central nervous system development
0.36	GO:0060591	chondroblast differentiation
0.35	GO:0009629	response to gravity
0.35	GO:0010447	response to acidic pH

0.85	GO:0005540	hyaluronic acid binding
0.66	GO:0005509	calcium ion binding
0.45	GO:0005201	extracellular matrix structural constituent
0.39	GO:0030246	carbohydrate binding
0.33	GO:0005515	protein binding

0.51	GO:0005578	proteinaceous extracellular matrix
0.51	GO:0044420	extracellular matrix component
0.47	GO:0005615	extracellular space
0.35	GO:0043025	neuronal cell body
0.34	GO:0043005	neuron projection
0.33	GO:0043202	lysosomal lumen
0.33	GO:0005796	Golgi lumen
0.30	GO:0016020	membrane

sp|P07916|ELN_CHICK
Elastin (Fragment)
Search

ELN

0.85	Tropoelastin

0.54	GO:0043149	stress fiber assembly
0.51	GO:0007519	skeletal muscle tissue development
0.51	GO:0030198	extracellular matrix organization
0.49	GO:0030833	regulation of actin filament polymerization
0.38	GO:0071298	cellular response to L-ascorbic acid
0.37	GO:0071280	cellular response to copper ion
0.37	GO:0071549	cellular response to dexamethasone stimulus
0.37	GO:0055093	response to hyperoxia
0.37	GO:0001974	blood vessel remodeling
0.37	GO:0071300	cellular response to retinoic acid

0.76	GO:0005201	extracellular matrix structural constituent
0.52	GO:0050840	extracellular matrix binding
0.39	GO:0030246	carbohydrate binding
0.38	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.38	GO:0005515	protein binding
0.37	GO:0097493	structural molecule activity conferring elasticity
0.35	GO:0003712	transcription cofactor activity
0.35	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0046872	metal ion binding
0.35	GO:0004672	protein kinase activity

0.70	GO:0005578	proteinaceous extracellular matrix
0.57	GO:0071953	elastic fiber
0.42	GO:0005739	mitochondrion
0.38	GO:0005581	collagen trimer
0.36	GO:0035060	brahma complex
0.35	GO:0005719	nuclear euchromatin
0.35	GO:0071565	nBAF complex
0.35	GO:0071564	npBAF complex
0.35	GO:0005615	extracellular space
0.35	GO:0016586	RSC-type complex

0.38

EC:3.2.1

GO:0004553

sp|P07997|HEM1_CHICK
5-aminolevulinate synthase, nonspecific, mitochondrial
Search

ALAS1

0.63	5-aminolevulinate synthase, nonspecific, mitochondrial

0.71	GO:0006782	protoporphyrinogen IX biosynthetic process
0.36	GO:0070541	response to platinum ion
0.35	GO:0032025	response to cobalt ion
0.35	GO:0034698	response to gonadotropin
0.35	GO:0051591	response to cAMP
0.35	GO:0045471	response to ethanol
0.35	GO:0010045	response to nickel cation
0.34	GO:0032869	cellular response to insulin stimulus
0.34	GO:0009635	response to herbicide
0.34	GO:0001666	response to hypoxia

0.84	GO:0003870	5-aminolevulinate synthase activity
0.67	GO:0070279	vitamin B6 binding
0.60	GO:0050662	coenzyme binding
0.53	GO:0043168	anion binding
0.49	GO:0042802	identical protein binding
0.34	GO:0016874	ligase activity

0.74	GO:0005759	mitochondrial matrix
0.47	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol

0.84	EC:2.3.1.37	GO:0003870
0.84	KEGG:R00830	GO:0003870

sp|P08023|ACTA_CHICK
Actin, aortic smooth muscle
Search

ACTA2

0.97	Actin aortic smooth muscle

0.78	GO:0090131	mesenchyme migration
0.63	GO:0010628	positive regulation of gene expression
0.41	GO:0003008	system process
0.41	GO:0072144	glomerular mesangial cell development
0.38	GO:0009615	response to virus
0.37	GO:0035296	regulation of tube diameter
0.37	GO:0061870	positive regulation of hepatic stellate cell migration
0.37	GO:0061873	regulation of hepatic stellate cell contraction
0.37	GO:2000491	positive regulation of hepatic stellate cell activation
0.37	GO:1903116	positive regulation of actin filament-based movement

0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0019901	protein kinase binding
0.35	GO:0005200	structural constituent of cytoskeleton

0.73	GO:0030175	filopodium
0.72	GO:0030027	lamellipodium
0.70	GO:0044297	cell body
0.48	GO:0032982	myosin filament
0.45	GO:0005737	cytoplasm
0.40	GO:0070062	extracellular exosome
0.38	GO:0072562	blood microparticle
0.38	GO:0097517	contractile actin filament bundle
0.38	GO:0042641	actomyosin
0.37	GO:0099512	supramolecular fiber

sp|P08070|TBA2_CHICK
Tubulin alpha-2 chain
Search

TUBA8

0.53	Tubulin alpha chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.37	GO:0045046	protein import into peroxisome membrane

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0032403	protein complex binding
0.34	GO:0005544	calcium-dependent phospholipid binding
0.33	GO:0005509	calcium ion binding

0.73	GO:0005874	microtubule
0.46	GO:0005737	cytoplasm
0.35	GO:0031301	integral component of organelle membrane
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.33	GO:0043231	intracellular membrane-bounded organelle

sp|P08106|HSP70_CHICK
Heat shock 70 kDa protein
Search

HSPA2

0.61	Inducible heat shock protein 70

0.65	GO:0009409	response to cold
0.61	GO:0009408	response to heat
0.56	GO:0031662	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle
0.56	GO:1901896	positive regulation of calcium-transporting ATPase activity
0.55	GO:0070194	synaptonemal complex disassembly
0.54	GO:0090084	negative regulation of inclusion body assembly
0.54	GO:0007141	male meiosis I
0.51	GO:0007286	spermatid development
0.50	GO:0042026	protein refolding
0.41	GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0051861	glycolipid binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.53	GO:0097718	disordered domain specific binding
0.48	GO:0019899	enzyme binding
0.48	GO:0051082	unfolded protein binding
0.42	GO:0055131	C3HC4-type RING finger domain binding
0.41	GO:0033142	progesterone receptor binding

0.54	GO:0036128	CatSper complex
0.54	GO:0072687	meiotic spindle
0.54	GO:0001673	male germ cell nucleus
0.53	GO:0043209	myelin sheath
0.52	GO:0000795	synaptonemal complex
0.48	GO:0009986	cell surface
0.47	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.41	GO:0070062	extracellular exosome
0.40	GO:0000974	Prp19 complex

0.36

GO:0016887

sp|P08110|ENPL_CHICK
Endoplasmin
Search

HSP90B1

0.84	Heat shock protein HSP 90-alpha

0.69	GO:0006457	protein folding
0.62	GO:0006950	response to stress
0.58	GO:0031247	actin rod assembly
0.56	GO:0071318	cellular response to ATP
0.54	GO:1903513	endoplasmic reticulum to cytosol transport
0.54	GO:0032527	protein exit from endoplasmic reticulum
0.53	GO:0036293	response to decreased oxygen levels
0.51	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.51	GO:0043666	regulation of phosphoprotein phosphatase activity
0.50	GO:0043066	negative regulation of apoptotic process

0.71	GO:0051082	unfolded protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0050750	low-density lipoprotein particle receptor binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0019903	protein phosphatase binding
0.42	GO:0003723	RNA binding
0.34	GO:0019104	DNA N-glycosylase activity
0.33	GO:0005509	calcium ion binding

0.55	GO:0005788	endoplasmic reticulum lumen
0.52	GO:0030496	midbody
0.51	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0034663	endoplasmic reticulum chaperone complex
0.48	GO:0005789	endoplasmic reticulum membrane
0.46	GO:0005829	cytosol
0.43	GO:0042470	melanosome
0.39	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion

0.34

EC:3.2.2

GO:0019104

sp|P08125|COAA1_CHICK
Collagen alpha-1(X) chain
Search

0.86	Collagen type VIII alpha 2 chain

0.47	GO:0050673	epithelial cell proliferation
0.46	GO:0048593	camera-type eye morphogenesis
0.38	GO:0001958	endochondral ossification
0.38	GO:0051216	cartilage development
0.36	GO:0030574	collagen catabolic process
0.36	GO:0030198	extracellular matrix organization
0.35	GO:0001525	angiogenesis
0.34	GO:0098609	cell-cell adhesion

0.38	GO:0005201	extracellular matrix structural constituent
0.34	GO:0030674	protein binding, bridging
0.32	GO:0046872	metal ion binding

0.78	GO:0005581	collagen trimer
0.61	GO:0005576	extracellular region
0.50	GO:0005938	cell cortex
0.39	GO:0043235	receptor complex
0.36	GO:0005788	endoplasmic reticulum lumen

sp|P08250|APOA1_CHICK
Apolipoprotein A-I
Search

APOA1

0.97	Apolipoprotein A-I preproprotein (Predicted)

0.75	GO:0042157	lipoprotein metabolic process
0.74	GO:0006869	lipid transport
0.67	GO:0008203	cholesterol metabolic process
0.65	GO:0030300	regulation of intestinal cholesterol absorption
0.64	GO:0034380	high-density lipoprotein particle assembly
0.64	GO:0010873	positive regulation of cholesterol esterification
0.63	GO:0060354	negative regulation of cell adhesion molecule production
0.63	GO:0018158	protein oxidation
0.63	GO:0034369	plasma lipoprotein particle remodeling
0.63	GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling

0.72	GO:0008289	lipid binding
0.66	GO:0070653	high-density lipoprotein particle receptor binding
0.65	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity
0.63	GO:0017127	cholesterol transporter activity
0.63	GO:0008035	high-density lipoprotein particle binding
0.62	GO:0034191	apolipoprotein A-I receptor binding
0.61	GO:0045499	chemorepellent activity
0.60	GO:0001540	amyloid-beta binding
0.60	GO:0043178	alcohol binding
0.54	GO:0031072	heat shock protein binding

0.69	GO:0034364	high-density lipoprotein particle
0.60	GO:0034385	triglyceride-rich plasma lipoprotein particle
0.56	GO:0030139	endocytic vesicle
0.53	GO:0031012	extracellular matrix
0.48	GO:0042627	chylomicron
0.47	GO:0072562	blood microparticle
0.39	GO:0034362	low-density lipoprotein particle
0.37	GO:0009986	cell surface
0.36	GO:0034774	secretory granule lumen
0.36	GO:0005788	endoplasmic reticulum lumen

sp|P08251|AT1B1_CHICK
Sodium/potassium-transporting ATPase subunit beta-1
Search

ATP1B1

0.80	Sodium/potassium-transporting ATPase subunit beta

0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.60	GO:1903281	positive regulation of calcium:sodium antiporter activity
0.60	GO:1903288	positive regulation of potassium ion import
0.60	GO:1903275	positive regulation of sodium ion export
0.59	GO:1903276	regulation of sodium ion export across plasma membrane
0.59	GO:0055119	relaxation of cardiac muscle
0.59	GO:0006883	cellular sodium ion homeostasis
0.58	GO:0086009	membrane repolarization
0.58	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling

0.57	GO:0005391	sodium:potassium-exchanging ATPase activity
0.57	GO:0051117	ATPase binding
0.55	GO:0008022	protein C-terminus binding
0.54	GO:0001671	ATPase activator activity
0.54	GO:0031402	sodium ion binding
0.52	GO:0019901	protein kinase binding
0.52	GO:0030955	potassium ion binding
0.42	GO:0030554	adenyl nucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0097367	carbohydrate derivative binding

0.85	GO:0005890	sodium:potassium-exchanging ATPase complex
0.56	GO:0014704	intercalated disc
0.56	GO:0042383	sarcolemma
0.54	GO:0043209	myelin sheath
0.54	GO:0016323	basolateral plasma membrane
0.54	GO:0016324	apical plasma membrane
0.40	GO:0005901	caveola
0.37	GO:0005622	intracellular
0.36	GO:0070062	extracellular exosome

0.57

GO:0005391

sp|P08267|FRIH_CHICK
Ferritin heavy chain
Search

FTH1

0.54	Ferritin heavy chain

0.76	GO:0006879	cellular iron ion homeostasis
0.75	GO:0006826	iron ion transport
0.50	GO:0051238	sequestering of metal ion
0.47	GO:0051651	maintenance of location in cell
0.43	GO:0008285	negative regulation of cell proliferation
0.42	GO:0006955	immune response
0.39	GO:0048145	regulation of fibroblast proliferation
0.37	GO:0055114	oxidation-reduction process
0.35	GO:0060547	negative regulation of necrotic cell death
0.35	GO:0002446	neutrophil mediated immunity

0.76	GO:0008199	ferric iron binding
0.46	GO:0016724	oxidoreductase activity, oxidizing metal ions, oxygen as acceptor
0.35	GO:0005515	protein binding

0.39	GO:0044754	autolysosome
0.36	GO:0005739	mitochondrion
0.36	GO:0031982	vesicle
0.36	GO:0043230	extracellular organelle
0.35	GO:0070288	ferritin complex
0.35	GO:0005615	extracellular space
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0005634	nucleus
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005829	cytosol

0.46

EC:1.16.3

GO:0016724

sp|P08284|H101_CHICK
Histone H1.01
Search

0.97	Histone cluster 1 H1 family member e

0.79	GO:0006334	nucleosome assembly
0.51	GO:0000122	negative regulation of transcription by RNA polymerase II
0.51	GO:0071169	establishment of protein localization to chromatin
0.50	GO:0051574	positive regulation of histone H3-K9 methylation
0.48	GO:0030307	positive regulation of cell growth
0.47	GO:0098532	histone H3-K27 trimethylation
0.47	GO:0050821	protein stabilization
0.46	GO:0080182	histone H3-K4 trimethylation
0.46	GO:0016584	nucleosome positioning
0.41	GO:0048260	positive regulation of receptor-mediated endocytosis

0.61	GO:0031490	chromatin DNA binding
0.48	GO:0042826	histone deacetylase binding
0.40	GO:0008201	heparin binding
0.35	GO:0046982	protein heterodimerization activity
0.35	GO:0003723	RNA binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.53	GO:0000792	heterochromatin
0.51	GO:0031974	membrane-enclosed lumen
0.50	GO:0000791	euchromatin
0.41	GO:0035327	transcriptionally active chromatin
0.40	GO:0031982	vesicle
0.39	GO:0009986	cell surface
0.37	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space

sp|P08285|H103_CHICK
Histone H1.03
Search

0.97	Histone cluster 1 H1 family member b

0.78	GO:0006334	nucleosome assembly
0.50	GO:0071169	establishment of protein localization to chromatin
0.49	GO:0051574	positive regulation of histone H3-K9 methylation
0.48	GO:0000122	negative regulation of transcription by RNA polymerase II
0.47	GO:0030307	positive regulation of cell growth
0.46	GO:0050821	protein stabilization
0.43	GO:0098532	histone H3-K27 trimethylation
0.42	GO:0080182	histone H3-K4 trimethylation
0.42	GO:0016584	nucleosome positioning
0.37	GO:0007517	muscle organ development

0.57	GO:0031490	chromatin DNA binding
0.48	GO:0042826	histone deacetylase binding
0.35	GO:0008201	heparin binding
0.34	GO:0003723	RNA binding
0.33	GO:0046982	protein heterodimerization activity

0.73	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.53	GO:0000792	heterochromatin
0.48	GO:0031974	membrane-enclosed lumen
0.42	GO:0000791	euchromatin
0.37	GO:0070062	extracellular exosome
0.35	GO:0035327	transcriptionally active chromatin
0.34	GO:0009986	cell surface

sp|P08286|H110_CHICK
Histone H1.10
Search

0.97	Histone cluster 1 H1 family member e

0.78	GO:0006334	nucleosome assembly
0.50	GO:0000122	negative regulation of transcription by RNA polymerase II
0.50	GO:0071169	establishment of protein localization to chromatin
0.49	GO:0051574	positive regulation of histone H3-K9 methylation
0.48	GO:0030307	positive regulation of cell growth
0.47	GO:0098532	histone H3-K27 trimethylation
0.46	GO:0050821	protein stabilization
0.46	GO:0080182	histone H3-K4 trimethylation
0.45	GO:0016584	nucleosome positioning
0.41	GO:0048260	positive regulation of receptor-mediated endocytosis

0.59	GO:0031490	chromatin DNA binding
0.48	GO:0042826	histone deacetylase binding
0.40	GO:0008201	heparin binding
0.35	GO:0003723	RNA binding
0.32	GO:0046982	protein heterodimerization activity

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.53	GO:0000792	heterochromatin
0.50	GO:0031974	membrane-enclosed lumen
0.47	GO:0000791	euchromatin
0.42	GO:0035327	transcriptionally active chromatin
0.39	GO:0031982	vesicle
0.39	GO:0009986	cell surface
0.37	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space

sp|P08287|H11L_CHICK
Histone H1.11L
Search

0.97	Histone cluster 1 H1 family member e

0.78	GO:0006334	nucleosome assembly
0.50	GO:0000122	negative regulation of transcription by RNA polymerase II
0.50	GO:0071169	establishment of protein localization to chromatin
0.49	GO:0051574	positive regulation of histone H3-K9 methylation
0.47	GO:0030307	positive regulation of cell growth
0.47	GO:0098532	histone H3-K27 trimethylation
0.46	GO:0050821	protein stabilization
0.46	GO:0080182	histone H3-K4 trimethylation
0.45	GO:0016584	nucleosome positioning
0.41	GO:0048260	positive regulation of receptor-mediated endocytosis

0.59	GO:0031490	chromatin DNA binding
0.48	GO:0042826	histone deacetylase binding
0.40	GO:0008201	heparin binding
0.34	GO:0003723	RNA binding
0.33	GO:0046982	protein heterodimerization activity

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.53	GO:0000792	heterochromatin
0.50	GO:0031974	membrane-enclosed lumen
0.49	GO:0000791	euchromatin
0.41	GO:0035327	transcriptionally active chromatin
0.39	GO:0031982	vesicle
0.39	GO:0009986	cell surface
0.36	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space

sp|P08288|H11R_CHICK
Histone H1.11R
Search

0.97	Histone cluster 1 H1 family member e

0.78	GO:0006334	nucleosome assembly
0.50	GO:0071169	establishment of protein localization to chromatin
0.50	GO:0000122	negative regulation of transcription by RNA polymerase II
0.49	GO:0051574	positive regulation of histone H3-K9 methylation
0.47	GO:0030307	positive regulation of cell growth
0.46	GO:0098532	histone H3-K27 trimethylation
0.46	GO:0050821	protein stabilization
0.45	GO:0080182	histone H3-K4 trimethylation
0.45	GO:0016584	nucleosome positioning
0.41	GO:0048260	positive regulation of receptor-mediated endocytosis

0.60	GO:0031490	chromatin DNA binding
0.48	GO:0042826	histone deacetylase binding
0.40	GO:0008201	heparin binding
0.36	GO:0032564	dATP binding
0.35	GO:0016208	AMP binding
0.35	GO:0003723	RNA binding
0.34	GO:0043531	ADP binding
0.34	GO:0003690	double-stranded DNA binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0032550	purine ribonucleoside binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.54	GO:0000792	heterochromatin
0.51	GO:0031974	membrane-enclosed lumen
0.47	GO:0000791	euchromatin
0.40	GO:0031982	vesicle
0.39	GO:0035327	transcriptionally active chromatin
0.39	GO:0009986	cell surface
0.38	GO:0043230	extracellular organelle
0.37	GO:0005615	extracellular space

sp|P08317|IL8_CHICK
Interleukin-8
Search

CXCL8

0.42	Multifunctional fusion protein (Fragment)

0.85	GO:0042119	neutrophil activation
0.85	GO:0030593	neutrophil chemotaxis
0.79	GO:0006954	inflammatory response
0.74	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.49	GO:0036446	myofibroblast differentiation
0.47	GO:0048246	macrophage chemotaxis
0.47	GO:0048147	negative regulation of fibroblast proliferation
0.47	GO:0002548	monocyte chemotaxis
0.46	GO:0048247	lymphocyte chemotaxis

0.86	GO:0005153	interleukin-8 receptor binding
0.84	GO:0008009	chemokine activity
0.35	GO:0008083	growth factor activity

0.72	GO:0005615	extracellular space
0.33	GO:0005622	intracellular

sp|P08629|THIO_CHICK
Thioredoxin
Search

TXN

0.51	Thioredoxin

0.73	GO:0006662	glycerol ether metabolic process
0.66	GO:0045454	cell redox homeostasis
0.51	GO:0055114	oxidation-reduction process
0.50	GO:0046822	regulation of nucleocytoplasmic transport
0.48	GO:0051223	regulation of protein transport
0.48	GO:0043388	positive regulation of DNA binding
0.47	GO:0051457	maintenance of protein location in nucleus
0.46	GO:1900180	regulation of protein localization to nucleus
0.46	GO:0032386	regulation of intracellular transport
0.45	GO:1904950	negative regulation of establishment of protein localization

0.70	GO:0015035	protein disulfide oxidoreductase activity
0.45	GO:0047134	protein-disulfide reductase activity
0.45	GO:0015037	peptide disulfide oxidoreductase activity
0.44	GO:0004791	thioredoxin-disulfide reductase activity
0.43	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
0.35	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.42	GO:0005634	nucleus
0.42	GO:0005829	cytosol
0.40	GO:0005576	extracellular region
0.39	GO:0005739	mitochondrion
0.35	GO:0031982	vesicle
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon

0.45	EC:1.8.1.8	GO:0047134
0.44	KEGG:R02016	GO:0004791

sp|P08636|RS17_CHICK
40S ribosomal protein S17
Search

RPS17

0.71	Ribosomal protein S17

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.50	GO:0000028	ribosomal small subunit assembly
0.47	GO:0034101	erythrocyte homeostasis
0.42	GO:0016072	rRNA metabolic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0003730	mRNA 3'-UTR binding
0.34	GO:0045182	translation regulator activity
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.49	GO:0044445	cytosolic part
0.42	GO:0044446	intracellular organelle part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle

0.32

GO:0016787

sp|P08641|CADH1_CHICK
Cadherin-1
Search

CDH1

0.95	Truncated E-cadherin

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.59	GO:0071681	cellular response to indole-3-methanol
0.58	GO:0051050	positive regulation of transport
0.58	GO:0071285	cellular response to lithium ion
0.56	GO:0060341	regulation of cellular localization
0.55	GO:0034332	adherens junction organization
0.55	GO:0031328	positive regulation of cellular biosynthetic process
0.55	GO:0022408	negative regulation of cell-cell adhesion
0.55	GO:0010628	positive regulation of gene expression
0.55	GO:0051796	negative regulation of timing of catagen

0.70	GO:0005509	calcium ion binding
0.58	GO:0045295	gamma-catenin binding
0.57	GO:0032794	GTPase activating protein binding
0.57	GO:0030506	ankyrin binding
0.54	GO:0008013	beta-catenin binding
0.54	GO:0045296	cadherin binding
0.50	GO:0042802	identical protein binding
0.38	GO:0045294	alpha-catenin binding
0.37	GO:0019903	protein phosphatase binding
0.36	GO:0019904	protein domain specific binding

0.59	GO:0005913	cell-cell adherens junction
0.58	GO:0016600	flotillin complex
0.57	GO:0016342	catenin complex
0.55	GO:0016328	lateral plasma membrane
0.54	GO:0030027	lamellipodium
0.53	GO:0030864	cortical actin cytoskeleton
0.53	GO:0043296	apical junction complex
0.53	GO:0005802	trans-Golgi network
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0009898	cytoplasmic side of plasma membrane

0.33	EC:3.5.2.17	GO:0033971
0.33	KEGG:R06601	GO:0033971

sp|P08642|RASH_CHICK
GTPase HRas
Search

HRAS

0.53	V-Ha-ras Harvey rat sarcoma viral oncogene homolog a

0.61	GO:0007165	signal transduction
0.53	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.52	GO:2000630	positive regulation of miRNA metabolic process
0.52	GO:1900029	positive regulation of ruffle assembly
0.51	GO:0090398	cellular senescence
0.51	GO:2000251	positive regulation of actin cytoskeleton reorganization
0.51	GO:0071480	cellular response to gamma radiation
0.51	GO:0043524	negative regulation of neuron apoptotic process
0.51	GO:0034260	negative regulation of GTPase activity
0.51	GO:0008284	positive regulation of cell proliferation

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.51	GO:0019003	GDP binding
0.49	GO:0008022	protein C-terminus binding
0.38	GO:0032403	protein complex binding
0.37	GO:0019002	GMP binding
0.36	GO:0030275	LRR domain binding
0.33	GO:0042802	identical protein binding
0.33	GO:0005198	structural molecule activity

0.45	GO:0005794	Golgi apparatus
0.42	GO:0005886	plasma membrane
0.39	GO:0098562	cytoplasmic side of membrane
0.39	GO:0019898	extrinsic component of membrane
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0031984	organelle subcompartment
0.36	GO:0020002	host cell plasma membrane
0.35	GO:0098857	membrane microdomain
0.34	GO:0005829	cytosol
0.34	GO:0048471	perinuclear region of cytoplasm

sp|P08836|FPPS_CHICK
Farnesyl pyrophosphate synthase
Search

FDPS

0.51	Farnesyl pyrophosphate synthetase

0.69	GO:0008299	isoprenoid biosynthetic process
0.47	GO:0045338	farnesyl diphosphate metabolic process
0.44	GO:0033383	geranyl diphosphate metabolic process
0.42	GO:0006695	cholesterol biosynthetic process
0.41	GO:0008654	phospholipid biosynthetic process
0.38	GO:0045540	regulation of cholesterol biosynthetic process
0.36	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development
0.36	GO:0090205	positive regulation of cholesterol metabolic process
0.36	GO:0033574	response to testosterone
0.36	GO:0070723	response to cholesterol

0.49	GO:0016740	transferase activity
0.35	GO:0046872	metal ion binding
0.34	GO:0003723	RNA binding

0.42	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol
0.38	GO:0005739	mitochondrion
0.35	GO:0005777	peroxisome
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.49

EC:2

GO:0016740

sp|P08938|PURP_CHICK
Purpurin
Search

0.97	Retinol binding protein 4, like

0.86	GO:0034633	retinol transport
0.50	GO:0001654	eye development
0.48	GO:0032526	response to retinoic acid
0.48	GO:0030277	maintenance of gastrointestinal epithelium
0.48	GO:0042572	retinol metabolic process
0.48	GO:0032024	positive regulation of insulin secretion
0.46	GO:0042593	glucose homeostasis
0.43	GO:0019319	hexose biosynthetic process
0.43	GO:0006006	glucose metabolic process
0.37	GO:0060157	urinary bladder development

0.86	GO:0034632	retinol transmembrane transporter activity
0.83	GO:0005501	retinoid binding
0.48	GO:0043178	alcohol binding
0.42	GO:0019842	vitamin binding
0.35	GO:0046982	protein heterodimerization activity

0.45	GO:0005615	extracellular space
0.35	GO:0033165	interphotoreceptor matrix
0.35	GO:1903561	extracellular vesicle
0.33	GO:0043234	protein complex
0.33	GO:0005829	cytosol

sp|P08940|MIM1_CHICK
Myeloid protein 1
Search

0.10	Myeloid protein 1

0.57	GO:0060271	cilium assembly
0.56	GO:0009617	response to bacterium
0.30	GO:0048869	cellular developmental process
0.30	GO:0009636	response to toxic substance
0.30	GO:0030097	hemopoiesis

0.65	GO:0042802	identical protein binding
0.30	GO:0043169	cation binding

0.40	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane
0.30	GO:0043227	membrane-bounded organelle
0.30	GO:0005576	extracellular region
0.30	GO:0043229	intracellular organelle

sp|P08941|ROS1_CHICK
Proto-oncogene tyrosine-protein kinase ROS
Search

ROS1

0.57	Tyrosine-protein kinase receptor

0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.60	GO:0010966	regulation of phosphate transport
0.56	GO:0002066	columnar/cuboidal epithelial cell development
0.56	GO:0070372	regulation of ERK1 and ERK2 cascade
0.55	GO:0046777	protein autophosphorylation
0.55	GO:0007283	spermatogenesis
0.55	GO:0032006	regulation of TOR signaling
0.54	GO:0008283	cell proliferation
0.54	GO:0001558	regulation of cell growth

0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.56	GO:0019903	protein phosphatase binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0042289	MHC class II protein binding
0.33	GO:0015321	sodium-dependent phosphate transmembrane transporter activity
0.32	GO:0008092	cytoskeletal protein binding

0.54	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0009986	cell surface
0.32	GO:0005856	cytoskeleton
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.80

EC:2.7.10.1

GO:0004714

sp|P08998|SOMA_CHICK
Somatotropin
Search

0.67	Somatotropin

0.76	GO:0010469	regulation of receptor activity
0.66	GO:0035846	oviduct epithelium development
0.57	GO:0043066	negative regulation of apoptotic process
0.57	GO:0006915	apoptotic process
0.54	GO:0010628	positive regulation of gene expression
0.51	GO:0010629	negative regulation of gene expression
0.42	GO:0032094	response to food
0.42	GO:0050691	regulation of defense response to virus by host
0.42	GO:0040018	positive regulation of multicellular organism growth
0.41	GO:0032869	cellular response to insulin stimulus

0.85	GO:0005131	growth hormone receptor binding
0.79	GO:0005179	hormone activity
0.62	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process
0.42	GO:0046872	metal ion binding

0.73	GO:0005615	extracellular space
0.41	GO:0030141	secretory granule
0.40	GO:0005802	trans-Golgi network
0.37	GO:0005634	nucleus
0.36	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P09102|PDIA1_CHICK
Protein disulfide-isomerase
Search

P4HB

0.48	Dolichyl-diphosphooligosaccharide--protein glycotransferase

0.68	GO:0045454	cell redox homeostasis
0.57	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.56	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline
0.55	GO:0046598	positive regulation of viral entry into host cell
0.53	GO:0034976	response to endoplasmic reticulum stress
0.52	GO:0071456	cellular response to hypoxia
0.42	GO:0006457	protein folding
0.41	GO:0055114	oxidation-reduction process
0.36	GO:0034378	chylomicron assembly
0.36	GO:0038155	interleukin-23-mediated signaling pathway

0.79	GO:0003756	protein disulfide isomerase activity
0.55	GO:0031545	peptidyl-proline 4-dioxygenase activity
0.53	GO:0019798	procollagen-proline dioxygenase activity
0.53	GO:0005178	integrin binding
0.51	GO:0015037	peptide disulfide oxidoreductase activity
0.50	GO:0046982	protein heterodimerization activity
0.37	GO:0019899	enzyme binding
0.34	GO:0003723	RNA binding
0.32	GO:0016740	transferase activity

0.69	GO:0005783	endoplasmic reticulum
0.52	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.51	GO:0009897	external side of plasma membrane
0.46	GO:1990204	oxidoreductase complex
0.43	GO:0044446	intracellular organelle part
0.43	GO:0042470	melanosome
0.43	GO:0043234	protein complex
0.40	GO:0043233	organelle lumen
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion

0.79

EC:5.3.4.1

GO:0003756

sp|P09203|TBB1_CHICK
Tubulin beta-1 chain
Search

0.57	Tubulin beta chain

0.71	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.52	GO:1902669	positive regulation of axon guidance
0.50	GO:0001764	neuron migration
0.35	GO:0031115	negative regulation of microtubule polymerization
0.33	GO:0070925	organelle assembly
0.33	GO:0022402	cell cycle process

0.77	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0046982	protein heterodimerization activity
0.34	GO:0042288	MHC class I protein binding
0.34	GO:0003725	double-stranded RNA binding
0.34	GO:0031625	ubiquitin protein ligase binding

0.73	GO:0005874	microtubule
0.46	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus
0.34	GO:0043209	myelin sheath
0.34	GO:0044297	cell body
0.34	GO:0031970	organelle envelope lumen
0.34	GO:0035770	ribonucleoprotein granule
0.33	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

sp|P09206|TBB3_CHICK
Tubulin beta-3 chain
Search

TUBB4B

0.49	Tubulin beta chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0042267	natural killer cell mediated cytotoxicity
0.35	GO:1902669	positive regulation of axon guidance
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0001764	neuron migration
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0003725	double-stranded RNA binding
0.35	GO:0042288	MHC class I protein binding
0.34	GO:0046982	protein heterodimerization activity
0.34	GO:0051082	unfolded protein binding

0.73	GO:0005874	microtubule
0.48	GO:0043209	myelin sheath
0.46	GO:0005737	cytoplasm
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:0045298	tubulin complex
0.35	GO:0031983	vesicle lumen
0.34	GO:0030496	midbody
0.34	GO:0005634	nucleus
0.34	GO:0097708	intracellular vesicle

sp|P09207|TBB6_CHICK
Tubulin beta-6 chain
Search

0.49	Tubulin beta chain

0.71	GO:0007017	microtubule-based process
0.70	GO:0007010	cytoskeleton organization
0.43	GO:0070925	organelle assembly
0.43	GO:0022402	cell cycle process
0.37	GO:0007411	axon guidance
0.35	GO:0000278	mitotic cell cycle
0.34	GO:0006915	apoptotic process

0.76	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0042277	peptide binding
0.33	GO:0005515	protein binding

0.73	GO:0005874	microtubule
0.46	GO:0005737	cytoplasm
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.37	GO:0030424	axon
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.33	GO:0071944	cell periphery

sp|P09244|TBB7_CHICK
Tubulin beta-7 chain
Search

TUBB

0.49	Tubulin beta chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.46	GO:0070925	organelle assembly
0.45	GO:0022402	cell cycle process
0.37	GO:1902669	positive regulation of axon guidance
0.36	GO:0001764	neuron migration
0.35	GO:0042267	natural killer cell mediated cytotoxicity
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.34	GO:0030705	cytoskeleton-dependent intracellular transport

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0042288	MHC class I protein binding
0.49	GO:0031625	ubiquitin protein ligase binding
0.39	GO:0032794	GTPase activating protein binding
0.37	GO:0019904	protein domain specific binding

0.73	GO:0005874	microtubule
0.53	GO:0005641	nuclear envelope lumen
0.50	GO:0044297	cell body
0.49	GO:0036464	cytoplasmic ribonucleoprotein granule
0.38	GO:0045121	membrane raft
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:0035578	azurophil granule lumen
0.35	GO:0045298	tubulin complex
0.33	GO:0005829	cytosol

sp|P09324|YES_CHICK
Tyrosine-protein kinase Yes
Search

YES1

0.58	Tyrosine-protein kinase Yes

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.50	GO:0046777	protein autophosphorylation
0.50	GO:0036120	cellular response to platelet-derived growth factor stimulus
0.49	GO:0071300	cellular response to retinoic acid
0.48	GO:0001932	regulation of protein phosphorylation
0.47	GO:0071560	cellular response to transforming growth factor beta stimulus
0.47	GO:0015758	glucose transport
0.46	GO:0042327	positive regulation of phosphorylation
0.46	GO:0045087	innate immune response
0.45	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

0.81	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0001784	phosphotyrosine residue binding
0.53	GO:0044325	ion channel binding
0.47	GO:0019899	enzyme binding
0.44	GO:0005102	receptor binding
0.33	GO:0032403	protein complex binding

0.47	GO:0005884	actin filament
0.47	GO:0005794	Golgi apparatus
0.47	GO:0005829	cytosol
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.39	GO:0005815	microtubule organizing center
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0016235	aggresome
0.34	GO:0032587	ruffle membrane
0.32	GO:0005634	nucleus

0.81

EC:2.7.10.2

GO:0004715

sp|P09479|ACHA_CHICK
Acetylcholine receptor subunit alpha
Search

CHRNA1

0.94	Nicotinic acetylcholine recepter alpha-subunit

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.47	GO:0007274	neuromuscular synaptic transmission
0.46	GO:0035094	response to nicotine
0.46	GO:0007271	synaptic transmission, cholinergic
0.46	GO:0048630	skeletal muscle tissue growth
0.44	GO:0070050	neuron cellular homeostasis
0.44	GO:0003009	skeletal muscle contraction
0.44	GO:0019228	neuronal action potential
0.44	GO:0046716	muscle cell cellular homeostasis

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.48	GO:0042166	acetylcholine binding
0.35	GO:0005515	protein binding

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.46	GO:0005892	acetylcholine-gated channel complex
0.43	GO:0031594	neuromuscular junction
0.41	GO:0009986	cell surface

sp|P09480|ACHA2_CHICK
Neuronal acetylcholine receptor subunit alpha-2
Search

CHRNA2

0.89	Nicotinic acetylcholine receptor alpha 2 subunit

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.54	GO:0035094	response to nicotine
0.53	GO:0007271	synaptic transmission, cholinergic
0.49	GO:0007274	neuromuscular synaptic transmission
0.46	GO:0060080	inhibitory postsynaptic potential
0.46	GO:0014059	regulation of dopamine secretion
0.46	GO:0035640	exploration behavior
0.45	GO:0007585	respiratory gaseous exchange
0.45	GO:0051899	membrane depolarization

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.51	GO:0042166	acetylcholine binding
0.33	GO:0005515	protein binding

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.57	GO:0005892	acetylcholine-gated channel complex
0.44	GO:0009897	external side of plasma membrane

sp|P09481|ACHA3_CHICK
Neuronal acetylcholine receptor subunit alpha-3
Search

CHRNA3

0.90	Cholinergic receptor nicotinic alpha 3 subunit

0.80	GO:0060079	excitatory postsynaptic potential
0.66	GO:0060084	synaptic transmission involved in micturition
0.64	GO:0035095	behavioral response to nicotine
0.60	GO:0034220	ion transmembrane transport
0.55	GO:0007399	nervous system development
0.41	GO:0006812	cation transport
0.38	GO:0007271	synaptic transmission, cholinergic

0.83	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.50	GO:0022850	serotonin-gated cation-selective channel activity
0.39	GO:0042166	acetylcholine binding
0.35	GO:0051537	2 iron, 2 sulfur cluster binding

0.79	GO:0045211	postsynaptic membrane
0.75	GO:0030054	cell junction
0.63	GO:0005892	acetylcholine-gated channel complex

sp|P09482|ACHA4_CHICK
Neuronal acetylcholine receptor subunit alpha-4
Search

CHRNA4

0.94	Cholinergic receptor nicotinic alpha 4 subunit

0.79	GO:0060079	excitatory postsynaptic potential
0.75	GO:0035094	response to nicotine
0.72	GO:0007271	synaptic transmission, cholinergic
0.71	GO:0060080	inhibitory postsynaptic potential
0.70	GO:0014059	regulation of dopamine secretion
0.69	GO:0035640	exploration behavior
0.69	GO:0007585	respiratory gaseous exchange
0.68	GO:0051899	membrane depolarization
0.68	GO:0019233	sensory perception of pain
0.67	GO:0001508	action potential

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.73	GO:0015464	acetylcholine receptor activity
0.58	GO:0042166	acetylcholine binding

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0005892	acetylcholine-gated channel complex
0.74	GO:0030054	cell junction
0.65	GO:0009897	external side of plasma membrane

sp|P09484|ACHB2_CHICK
Neuronal acetylcholine receptor subunit beta-2
Search

CHRNB2

0.91	Neuronal nicotinic acetylcholine receptor beta 2 subunit

0.80	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.51	GO:0035094	response to nicotine
0.50	GO:0007274	neuromuscular synaptic transmission
0.49	GO:0060073	micturition
0.49	GO:0021771	lateral geniculate nucleus development
0.48	GO:0042320	regulation of circadian sleep/wake cycle, REM sleep
0.48	GO:0033603	positive regulation of dopamine secretion
0.48	GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep
0.48	GO:0001661	conditioned taste aversion

0.83	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.49	GO:0042166	acetylcholine binding
0.40	GO:0046982	protein heterodimerization activity

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.50	GO:0005892	acetylcholine-gated channel complex
0.45	GO:0009897	external side of plasma membrane
0.43	GO:0043204	perikaryon
0.42	GO:0030425	dendrite
0.42	GO:0030424	axon
0.42	GO:0044853	plasma membrane raft
0.35	GO:0005737	cytoplasm

sp|P09531|TGFB1_CHICK
Transforming growth factor beta-1 (Fragment)
Search

TGFB1

0.86	Transforming growth factor beta

0.80	GO:0016049	cell growth
0.77	GO:0010936	negative regulation of macrophage cytokine production
0.76	GO:0043932	ossification involved in bone remodeling
0.76	GO:0032570	response to progesterone
0.76	GO:0010469	regulation of receptor activity
0.74	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.74	GO:0032967	positive regulation of collagen biosynthetic process
0.73	GO:0007435	salivary gland morphogenesis
0.73	GO:0045778	positive regulation of ossification
0.72	GO:0070169	positive regulation of biomineral tissue development

0.84	GO:0005160	transforming growth factor beta receptor binding
0.78	GO:0008083	growth factor activity
0.63	GO:0003823	antigen binding
0.59	GO:0042802	identical protein binding
0.57	GO:0050431	transforming growth factor beta binding
0.53	GO:0043539	protein serine/threonine kinase activator activity
0.51	GO:0005125	cytokine activity
0.47	GO:0019899	enzyme binding
0.44	GO:0001540	amyloid-beta binding
0.42	GO:0046983	protein dimerization activity

0.72	GO:0005615	extracellular space
0.60	GO:0031012	extracellular matrix
0.57	GO:0009986	cell surface
0.55	GO:0005902	microvillus
0.49	GO:0005634	nucleus
0.42	GO:0043025	neuronal cell body
0.41	GO:0005737	cytoplasm
0.39	GO:0030424	axon
0.39	GO:0097708	intracellular vesicle
0.38	GO:0012505	endomembrane system

sp|P09540|MLEX_CHICK
Myosin light chain, embryonic
Search

MYL4

0.97	Myosin light chain, embryonic

0.55	GO:0002026	regulation of the force of heart contraction
0.54	GO:0060048	cardiac muscle contraction
0.49	GO:0032781	positive regulation of ATPase activity
0.41	GO:0014706	striated muscle tissue development
0.41	GO:0007517	muscle organ development
0.41	GO:0003208	cardiac ventricle morphogenesis
0.41	GO:0006942	regulation of striated muscle contraction
0.39	GO:0048729	tissue morphogenesis
0.39	GO:0030049	muscle filament sliding
0.35	GO:0060055	angiogenesis involved in wound healing

0.70	GO:0005509	calcium ion binding
0.53	GO:0003785	actin monomer binding
0.48	GO:0051015	actin filament binding
0.41	GO:0008307	structural constituent of muscle
0.38	GO:0030898	actin-dependent ATPase activity
0.35	GO:0032038	myosin II heavy chain binding
0.35	GO:0003774	motor activity
0.33	GO:0004872	receptor activity

0.54	GO:0031672	A band
0.42	GO:0016459	myosin complex
0.40	GO:0031674	I band
0.40	GO:0005903	brush border
0.35	GO:0005829	cytosol
0.34	GO:0031012	extracellular matrix
0.34	GO:0008305	integrin complex
0.34	GO:0070062	extracellular exosome

sp|P09572|AT1A1_CHICK
Sodium/potassium-transporting ATPase subunit alpha-1
Search

ATP1A1

0.64	Sodium/potassium-transporting ATPase subunit alpha

0.85	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.76	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.53	GO:1903416	response to glycoside
0.53	GO:0006883	cellular sodium ion homeostasis
0.52	GO:0086009	membrane repolarization
0.52	GO:0031947	negative regulation of glucocorticoid biosynthetic process
0.51	GO:0045989	positive regulation of striated muscle contraction
0.51	GO:0030007	cellular potassium ion homeostasis

0.85	GO:0005391	sodium:potassium-exchanging ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.54	GO:0046872	metal ion binding
0.52	GO:1990239	steroid hormone binding
0.47	GO:0051087	chaperone binding
0.44	GO:0016791	phosphatase activity
0.38	GO:0030506	ankyrin binding

0.53	GO:0042383	sarcolemma
0.51	GO:0005890	sodium:potassium-exchanging ATPase complex
0.49	GO:0014069	postsynaptic density
0.49	GO:0043209	myelin sheath
0.48	GO:0016323	basolateral plasma membrane
0.48	GO:0016324	apical plasma membrane
0.41	GO:0043234	protein complex
0.38	GO:0014704	intercalated disc
0.37	GO:0005901	caveola
0.37	GO:0031410	cytoplasmic vesicle

0.85

GO:0005391

sp|P09642|TBA3_CHICK
Tubulin alpha-3 chain (Fragment)
Search

0.53	Tubulin alpha chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.37	GO:0045046	protein import into peroxisome membrane

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0032403	protein complex binding

0.73	GO:0005874	microtubule
0.46	GO:0005737	cytoplasm
0.35	GO:0031301	integral component of organelle membrane
0.35	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.33	GO:0043231	intracellular membrane-bounded organelle

sp|P09643|TBA4_CHICK
Tubulin alpha-4 chain (Fragment)
Search

TUBA8

0.53	Tubulin alpha chain

0.71	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.35	GO:0045046	protein import into peroxisome membrane
0.34	GO:0021782	glial cell development
0.34	GO:0042552	myelination

0.77	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0032403	protein complex binding

0.73	GO:0005874	microtubule
0.46	GO:0005737	cytoplasm
0.34	GO:0031301	integral component of organelle membrane
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.32	GO:0043231	intracellular membrane-bounded organelle

sp|P09644|TBA5_CHICK
Tubulin alpha-5 chain
Search

TUBA4A

0.53	Tubulin alpha chain

0.71	GO:0007017	microtubule-based process
0.70	GO:0007010	cytoskeleton organization
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0002576	platelet degranulation
0.35	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.34	GO:0030705	cytoskeleton-dependent intracellular transport
0.33	GO:0051301	cell division

0.76	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0019901	protein kinase binding

0.72	GO:0005874	microtubule
0.47	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus

sp|P09645|TBA8_CHICK
Tubulin alpha-8 chain (Fragment)
Search

0.53	Tubulin alpha chain

0.71	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.35	GO:0045046	protein import into peroxisome membrane

0.77	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0032403	protein complex binding

0.73	GO:0005874	microtubule
0.46	GO:0005737	cytoplasm
0.34	GO:0031301	integral component of organelle membrane
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.32	GO:0043231	intracellular membrane-bounded organelle

sp|P09648|CATL1_CHICK
Cathepsin L1 (Fragments)
Search

CTSL

0.65	Procathepsin L

0.61	GO:0006508	proteolysis
0.45	GO:0044257	cellular protein catabolic process
0.43	GO:0010839	negative regulation of keratinocyte proliferation
0.43	GO:0046697	decidualization
0.43	GO:0031069	hair follicle morphogenesis
0.43	GO:2000249	regulation of actin cytoskeleton reorganization
0.40	GO:0097067	cellular response to thyroid hormone stimulus
0.39	GO:0051604	protein maturation
0.39	GO:0030574	collagen catabolic process
0.38	GO:0002250	adaptive immune response

0.72	GO:0008234	cysteine-type peptidase activity
0.43	GO:0042393	histone binding
0.42	GO:0004175	endopeptidase activity
0.41	GO:0097655	serpin family protein binding
0.39	GO:0004180	carboxypeptidase activity
0.39	GO:0001968	fibronectin binding
0.39	GO:0043394	proteoglycan binding
0.38	GO:0032403	protein complex binding
0.37	GO:0030984	kininogen binding
0.35	GO:0042277	peptide binding

0.50	GO:0005764	lysosome
0.47	GO:0005615	extracellular space
0.40	GO:0005730	nucleolus
0.39	GO:0031410	cytoplasmic vesicle
0.36	GO:0043204	perikaryon
0.36	GO:0005902	microvillus
0.35	GO:0009897	external side of plasma membrane
0.35	GO:0045177	apical part of cell
0.35	GO:0043005	neuron projection
0.34	GO:0005775	vacuolar lumen

0.72

GO:0008234

sp|P09652|TBB4_CHICK
Tubulin beta-4 chain
Search

0.49	Tubulin beta chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.46	GO:0007411	axon guidance
0.44	GO:0007186	G-protein coupled receptor signaling pathway
0.36	GO:0000278	mitotic cell cycle
0.34	GO:0006915	apoptotic process
0.33	GO:0035556	intracellular signal transduction

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0004930	G-protein coupled receptor activity
0.37	GO:0042277	peptide binding
0.35	GO:0042288	MHC class I protein binding
0.34	GO:0031625	ubiquitin protein ligase binding

0.73	GO:0005874	microtubule
0.45	GO:0044297	cell body
0.45	GO:0030425	dendrite
0.45	GO:0030424	axon
0.43	GO:0005737	cytoplasm
0.38	GO:0071944	cell periphery
0.37	GO:0070062	extracellular exosome
0.35	GO:0005634	nucleus
0.34	GO:0031970	organelle envelope lumen
0.34	GO:0035770	ribonucleoprotein granule

sp|P09653|TBB5_CHICK
Tubulin beta-5 chain
Search

TUBB6

0.49	Tubulin beta chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.43	GO:0007411	axon guidance
0.42	GO:0007186	G-protein coupled receptor signaling pathway
0.36	GO:0000278	mitotic cell cycle
0.34	GO:0006915	apoptotic process

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0004930	G-protein coupled receptor activity
0.37	GO:0042277	peptide binding
0.34	GO:0005515	protein binding

0.73	GO:0005874	microtubule
0.44	GO:0005737	cytoplasm
0.43	GO:0043025	neuronal cell body
0.43	GO:0030425	dendrite
0.42	GO:0030424	axon
0.38	GO:0070062	extracellular exosome
0.36	GO:0071944	cell periphery
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P09654|VIME_CHICK
Vimentin
Search

VIM

0.85	Putative nuclear envelope protein lamin intermediate filament superfamily

0.58	GO:0060020	Bergmann glial cell differentiation
0.58	GO:0070307	lens fiber cell development
0.57	GO:0010714	positive regulation of collagen metabolic process
0.57	GO:0032965	regulation of collagen biosynthetic process
0.57	GO:0014002	astrocyte development
0.57	GO:0045109	intermediate filament organization
0.56	GO:0060395	SMAD protein signal transduction
0.56	GO:0071346	cellular response to interferon-gamma
0.55	GO:0010977	negative regulation of neuron projection development
0.55	GO:0043488	regulation of mRNA stability

0.62	GO:0005198	structural molecule activity
0.59	GO:1990254	keratin filament binding
0.57	GO:0097110	scaffold protein binding
0.55	GO:0008022	protein C-terminus binding
0.52	GO:0019904	protein domain specific binding
0.52	GO:0003725	double-stranded RNA binding
0.50	GO:0042802	identical protein binding
0.35	GO:0051721	protein phosphatase 2A binding
0.34	GO:0019901	protein kinase binding

0.79	GO:0005882	intermediate filament
0.55	GO:0045335	phagocytic vesicle
0.54	GO:0005844	polysome
0.53	GO:0031252	cell leading edge
0.52	GO:0043005	neuron projection
0.51	GO:0005777	peroxisome
0.48	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion

sp|P09859|ANTR_CHICK
Gastrin/cholecystokinin-like peptide
Search

0.97	Gastrin/cholecystokinin-like peptide

0.76	GO:0010469	regulation of receptor activity
0.65	GO:0007586	digestion

0.79

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

sp|P09860|TNNC1_CHICK
Troponin C, slow skeletal and cardiac muscles
Search

TNNC1

0.94	Troponin C, slow skeletal and cardiac muscles

0.61	GO:0006941	striated muscle contraction
0.60	GO:0060047	heart contraction
0.59	GO:0032972	regulation of muscle filament sliding speed
0.58	GO:0003231	cardiac ventricle development
0.57	GO:0014883	transition between fast and slow fiber
0.56	GO:0003229	ventricular cardiac muscle tissue development
0.56	GO:0055008	cardiac muscle tissue morphogenesis
0.55	GO:0003206	cardiac chamber morphogenesis
0.52	GO:0043462	regulation of ATPase activity
0.50	GO:0050881	musculoskeletal movement

0.68	GO:0005509	calcium ion binding
0.59	GO:0031014	troponin T binding
0.58	GO:0031013	troponin I binding
0.58	GO:0048306	calcium-dependent protein binding
0.54	GO:0051015	actin filament binding
0.51	GO:0042803	protein homodimerization activity

0.59	GO:1990584	cardiac Troponin complex
0.35	GO:0097512	cardiac myofibril
0.33	GO:0005829	cytosol

sp|P09987|H1_CHICK
Histone H1
Search

0.96	Histone cluster 1 H1 family member e

0.78	GO:0006334	nucleosome assembly
0.53	GO:0000122	negative regulation of transcription by RNA polymerase II
0.52	GO:0098532	histone H3-K27 trimethylation
0.50	GO:0071169	establishment of protein localization to chromatin
0.50	GO:0080182	histone H3-K4 trimethylation
0.50	GO:0051574	positive regulation of histone H3-K9 methylation
0.50	GO:0016584	nucleosome positioning
0.48	GO:0030307	positive regulation of cell growth
0.47	GO:0050821	protein stabilization
0.37	GO:0048260	positive regulation of receptor-mediated endocytosis

0.62	GO:0031490	chromatin DNA binding
0.48	GO:0042826	histone deacetylase binding
0.39	GO:0032564	dATP binding
0.37	GO:0008201	heparin binding
0.37	GO:0016208	AMP binding
0.36	GO:0043531	ADP binding
0.36	GO:0003690	double-stranded DNA binding
0.35	GO:0003723	RNA binding
0.35	GO:0005509	calcium ion binding
0.35	GO:0032550	purine ribonucleoside binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.56	GO:0000792	heterochromatin
0.52	GO:0031974	membrane-enclosed lumen
0.50	GO:0000791	euchromatin
0.46	GO:0035327	transcriptionally active chromatin
0.39	GO:0031982	vesicle
0.38	GO:0043230	extracellular organelle
0.37	GO:0005615	extracellular space
0.36	GO:0009986	cell surface

sp|P0C1H3|H2B1_CHICK
Histone H2B 1/2/3/4/6
Search

sp|P0C1H4|H2B5_CHICK
Histone H2B 5
Search

sp|P0C1H5|H2B7_CHICK
Histone H2B 7
Search

sp|P0C597|DUPD1_CHICK
Dual specificity phosphatase DUPD1
Search

DUPD1

0.97	Dual specificity phosphatase and pro isomerase domain containing 1

0.73	GO:0035335	peptidyl-tyrosine dephosphorylation
0.37	GO:0043622	cortical microtubule organization
0.37	GO:0009737	response to abscisic acid
0.35	GO:1902310	positive regulation of peptidyl-serine dephosphorylation
0.35	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation
0.35	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.34	GO:0000122	negative regulation of transcription by RNA polymerase II
0.34	GO:0045785	positive regulation of cell adhesion
0.33	GO:0016310	phosphorylation
0.32	GO:0043043	peptide biosynthetic process

0.79	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.49	GO:0042803	protein homodimerization activity
0.35	GO:0001102	RNA polymerase II activating transcription factor binding
0.34	GO:0002039	p53 binding
0.34	GO:0004647	phosphoserine phosphatase activity
0.34	GO:0016301	kinase activity
0.32	GO:0003735	structural constituent of ribosome
0.32	GO:0016853	isomerase activity

0.43	GO:0043234	protein complex
0.36	GO:0005737	cytoplasm
0.33	GO:0012505	endomembrane system
0.33	GO:0005634	nucleus
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.79

EC:3.1.3

GO:0008138

sp|P0C7A1|ENASE_CHICK
Cytosolic endo-beta-N-acetylglucosaminidase
Search

ENGASE

0.73	Cytosolic endo-beta-N-acetylglucosaminidase

0.58	GO:0006517	protein deglycosylation
0.39	GO:0044041	multi-organism carbohydrate catabolic process
0.39	GO:0044278	cell wall disruption in other organism
0.36	GO:0009617	response to bacterium
0.36	GO:0006491	N-glycan processing
0.36	GO:0009253	peptidoglycan catabolic process
0.34	GO:0006457	protein folding
0.33	GO:2000860	positive regulation of aldosterone secretion
0.33	GO:0090331	negative regulation of platelet aggregation
0.33	GO:0007204	positive regulation of cytosolic calcium ion concentration

0.84	GO:0033925	mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
0.38	GO:0016231	beta-N-acetylglucosaminidase activity
0.33	GO:0005518	collagen binding

0.48	GO:0005737	cytoplasm
0.42	GO:0005581	collagen trimer
0.40	GO:0005576	extracellular region
0.40	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0005887	integral component of plasma membrane

0.84

EC:3.2.1.96

GO:0033925

sp|P0C915|OCC1_CHICK
Overexpressed in colon carcinoma 1 protein homolog
Search

0.97	Overexpressed in colon carcinoma 1 protein homolog

sp|P0CB05|CEP63_CHICK
Centrosomal protein of 63 kDa
Search

CEP63

0.85	Centrosomal protein of

0.85	GO:0098534	centriole assembly
0.84	GO:0051298	centrosome duplication
0.66	GO:1903251	multi-ciliated epithelial cell differentiation
0.53	GO:0042770	signal transduction in response to DNA damage
0.52	GO:0051225	spindle assembly
0.51	GO:0000077	DNA damage checkpoint
0.46	GO:0051301	cell division
0.42	GO:0051640	organelle localization
0.41	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
0.41	GO:0071539	protein localization to centrosome

0.38

GO:0005515

protein binding

0.76	GO:0005813	centrosome
0.63	GO:0005814	centriole
0.51	GO:0000922	spindle pole
0.38	GO:0098536	deuterosome
0.37	GO:0005829	cytosol

sp|P0CB50|PRDX1_CHICK
Peroxiredoxin-1
Search

PRDX1

0.85	Natural killer cell enhancing factor

0.69	GO:0098869	cellular oxidant detoxification
0.68	GO:0045454	cell redox homeostasis
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0030101	natural killer cell activation
0.51	GO:0042267	natural killer cell mediated cytotoxicity
0.50	GO:0042345	regulation of NF-kappaB import into nucleus
0.49	GO:0034101	erythrocyte homeostasis
0.49	GO:0032872	regulation of stress-activated MAPK cascade
0.48	GO:0042744	hydrogen peroxide catabolic process
0.48	GO:0008283	cell proliferation

0.74	GO:0051920	peroxiredoxin activity
0.49	GO:0045296	cadherin binding
0.47	GO:0004601	peroxidase activity
0.46	GO:0042802	identical protein binding
0.34	GO:0003676	nucleic acid binding
0.33	GO:0046983	protein dimerization activity
0.33	GO:0020037	heme binding

0.49	GO:0043209	myelin sheath
0.43	GO:0005634	nucleus
0.41	GO:0005739	mitochondrion
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:0005829	cytosol
0.34	GO:0042470	melanosome
0.34	GO:0031907	microbody lumen
0.34	GO:0000791	euchromatin
0.34	GO:0044439	peroxisomal part

0.74	EC:1.11.1.15	GO:0051920
0.47	KEGG:R03532	GO:0004601

sp|P0CF65|CRBN_CHICK
Protein cereblon
Search

CRBN

0.94

Cereblon

0.53	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.50	GO:0016567	protein ubiquitination
0.39	GO:0032463	negative regulation of protein homooligomerization
0.39	GO:0090073	positive regulation of protein homodimerization activity
0.38	GO:0034766	negative regulation of ion transmembrane transport
0.35	GO:0035118	embryonic pectoral fin morphogenesis
0.35	GO:0071600	otic vesicle morphogenesis
0.34	GO:0060173	limb development

0.52	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.57	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex
0.50	GO:0005730	nucleolus
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P0CG62|UBB_CHICK
Polyubiquitin-B
Search

0.49	Polyubiquitin-B Ubiquitin

0.46	GO:0019082	viral protein processing
0.41	GO:0006508	proteolysis
0.30	GO:0046483	heterocycle metabolic process
0.30	GO:0009058	biosynthetic process
0.30	GO:0006974	cellular response to DNA damage stimulus
0.30	GO:0034641	cellular nitrogen compound metabolic process
0.30	GO:1901360	organic cyclic compound metabolic process
0.30	GO:0044260	cellular macromolecule metabolic process
0.30	GO:0006725	cellular aromatic compound metabolic process

0.44

GO:0004252

serine-type endopeptidase activity

0.60	GO:0005840	ribosome
0.30	GO:0070013	intracellular organelle lumen
0.30	GO:0044428	nuclear part

0.44

GO:0004252

sp|P0DJH6|CENPW_CHICK
Centromere protein W
Search

CENPW

0.97	Centromere protein W

0.84	GO:0051382	kinetochore assembly
0.75	GO:0000278	mitotic cell cycle
0.52	GO:0007059	chromosome segregation
0.38	GO:0051301	cell division
0.37	GO:0034080	CENP-A containing nucleosome assembly
0.34	GO:0032259	methylation

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.34	GO:0008168	methyltransferase activity

0.56	GO:0000776	kinetochore
0.51	GO:0005654	nucleoplasm
0.40	GO:0000779	condensed chromosome, centromeric region
0.38	GO:0016363	nuclear matrix
0.37	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.1.1

GO:0008168

sp|P0DJH7|CENPX_CHICK
Centromere protein X
Search

0.87	Centromere protein X

0.84	GO:0051382	kinetochore assembly
0.65	GO:0006281	DNA repair
0.55	GO:0000712	resolution of meiotic recombination intermediates
0.54	GO:0031297	replication fork processing
0.43	GO:0051301	cell division
0.39	GO:0034080	CENP-A containing nucleosome assembly
0.38	GO:0031398	positive regulation of protein ubiquitination

0.54	GO:0046982	protein heterodimerization activity
0.48	GO:0003690	double-stranded DNA binding

0.55	GO:0071821	FANCM-MHF complex
0.54	GO:0043240	Fanconi anaemia nuclear complex
0.47	GO:0000777	condensed chromosome kinetochore

sp|P0DJJ2|ASTL_CHICK
Astacin-like metalloendopeptidase
Search

0.59	Metalloendopeptidase

0.60	GO:0006508	proteolysis
0.45	GO:2000360	negative regulation of binding of sperm to zona pellucida
0.44	GO:0060468	prevention of polyspermy
0.43	GO:0010954	positive regulation of protein processing
0.40	GO:0007155	cell adhesion
0.33	GO:0018996	molting cycle, collagen and cuticulin-based cuticle
0.32	GO:0000188	inactivation of MAPK activity
0.32	GO:0035335	peptidyl-tyrosine dephosphorylation

0.69	GO:0004222	metalloendopeptidase activity
0.62	GO:0008270	zinc ion binding
0.45	GO:0070002	glutamic-type peptidase activity
0.39	GO:0070001	aspartic-type peptidase activity
0.32	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.32	GO:0005515	protein binding
0.32	GO:0004725	protein tyrosine phosphatase activity

0.44	GO:0060473	cortical granule
0.38	GO:0030133	transport vesicle
0.36	GO:0005886	plasma membrane

0.69

GO:0004222

sp|P0DMQ6|DHSO_CHICK
Sorbitol dehydrogenase
Search

SORD

0.60	Sorbitol dehydrogenase

0.60	GO:0046370	fructose biosynthetic process
0.60	GO:0006062	sorbitol catabolic process
0.59	GO:0051160	L-xylitol catabolic process
0.54	GO:0030317	flagellated sperm motility
0.53	GO:0055114	oxidation-reduction process
0.37	GO:0046686	response to cadmium ion
0.37	GO:0046688	response to copper ion
0.37	GO:0006970	response to osmotic stress
0.37	GO:0031667	response to nutrient levels
0.36	GO:0009725	response to hormone

0.62	GO:0008270	zinc ion binding
0.57	GO:0003939	L-iditol 2-dehydrogenase activity
0.49	GO:0042802	identical protein binding
0.47	GO:0051287	NAD binding
0.38	GO:0046526	D-xylulose reductase activity
0.33	GO:0030246	carbohydrate binding
0.33	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.52	GO:0070062	extracellular exosome
0.52	GO:0031514	motile cilium
0.44	GO:0005739	mitochondrion
0.37	GO:0031967	organelle envelope
0.37	GO:0031090	organelle membrane
0.34	GO:0032991	macromolecular complex
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.57	EC:1.1.1.14	GO:0003939
0.38	KEGG:R01896	GO:0046526

sp|P10039|TENA_CHICK
Tenascin
Search

TNC

0.54	Tenascin C

0.76	GO:0042127	regulation of cell proliferation
0.72	GO:0007155	cell adhesion
0.64	GO:0060739	mesenchymal-epithelial cell signaling involved in prostate gland development
0.63	GO:0014012	peripheral nervous system axon regeneration
0.60	GO:0060740	prostate gland epithelium morphogenesis
0.58	GO:0007528	neuromuscular junction development
0.52	GO:0010628	positive regulation of gene expression
0.50	GO:0048522	positive regulation of cellular process
0.48	GO:0071798	response to prostaglandin D
0.48	GO:0060447	bud outgrowth involved in lung branching

0.62	GO:0045545	syndecan binding
0.39	GO:0001968	fibronectin binding

0.74	GO:0031012	extracellular matrix
0.52	GO:0005615	extracellular space
0.42	GO:0005925	focal adhesion
0.38	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016020	membrane

sp|P10042|CRBA1_CHICK
Beta-crystallin A3
Search

CRYBA1

0.97	Beta crystallin A3 chain transcript CN (Fragment)

0.65	GO:0007601	visual perception
0.44	GO:2000210	positive regulation of anoikis
0.44	GO:0043010	camera-type eye development
0.43	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling
0.43	GO:0051898	negative regulation of protein kinase B signaling
0.42	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.42	GO:0032007	negative regulation of TOR signaling
0.42	GO:0001818	negative regulation of cytokine production

0.68	GO:0005212	structural constituent of eye lens
0.38	GO:0042803	protein homodimerization activity

0.37	GO:0005634	nucleus
0.36	GO:0005861	troponin complex

sp|P10157|ETS2_CHICK
Protein C-ets-2
Search

ETS2

0.63	ETS proto-oncogene 2, transcription factor

0.58	GO:0001712	ectodermal cell fate commitment
0.57	GO:0090009	primitive streak formation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0007498	mesoderm development
0.50	GO:0051254	positive regulation of RNA metabolic process
0.49	GO:0010557	positive regulation of macromolecule biosynthetic process
0.49	GO:0031328	positive regulation of cellular biosynthetic process
0.48	GO:0051253	negative regulation of RNA metabolic process

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.52	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0019904	protein domain specific binding
0.49	GO:0003690	double-stranded DNA binding
0.40	GO:0035259	glucocorticoid receptor binding
0.33	GO:0042802	identical protein binding

0.61	GO:0005634	nucleus
0.48	GO:0005829	cytosol
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.42	GO:0005886	plasma membrane
0.33	GO:0005667	transcription factor complex
0.33	GO:0042025	host cell nucleus

sp|P10184|IOV7_CHICK
Ovoinhibitor
Search

0.10	Ovoinhibitor

0.63	GO:0010951	negative regulation of endopeptidase activity
0.54	GO:0043113	receptor clustering
0.53	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.46	GO:0006508	proteolysis
0.39	GO:0010751	negative regulation of nitric oxide mediated signal transduction
0.39	GO:1902572	negative regulation of serine-type peptidase activity
0.39	GO:1900003	regulation of serine-type endopeptidase activity
0.39	GO:0060046	regulation of acrosome reaction
0.39	GO:0090281	negative regulation of calcium ion import
0.39	GO:0048240	sperm capacitation

0.65	GO:0004867	serine-type endopeptidase inhibitor activity
0.54	GO:0043236	laminin binding
0.52	GO:0005509	calcium ion binding
0.46	GO:0008233	peptidase activity
0.38	GO:0004725	protein tyrosine phosphatase activity
0.38	GO:0005520	insulin-like growth factor binding
0.30	GO:0015459	potassium channel regulator activity
0.30	GO:0019899	enzyme binding
0.30	GO:0008200	ion channel inhibitor activity

0.41	GO:0005886	plasma membrane
0.41	GO:0005605	basal lamina
0.38	GO:0001669	acrosomal vesicle
0.37	GO:0005829	cytosol
0.36	GO:0005615	extracellular space
0.30	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.46

GO:0008233

sp|P10286|CALCA_CHICK
Calcitonin gene-related peptide
Search

0.96	Calcitonin

0.76	GO:0010469	regulation of receptor activity
0.45	GO:0055074	calcium ion homeostasis
0.41	GO:0045779	negative regulation of bone resorption
0.41	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.40	GO:0072503	cellular divalent inorganic cation homeostasis
0.40	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.40	GO:0002548	monocyte chemotaxis
0.39	GO:0006875	cellular metal ion homeostasis
0.39	GO:0010562	positive regulation of phosphorus metabolic process
0.38	GO:0051347	positive regulation of transferase activity

0.79	GO:0005179	hormone activity
0.42	GO:0031716	calcitonin receptor binding
0.38	GO:0042802	identical protein binding
0.35	GO:0032403	protein complex binding

0.66	GO:0005576	extracellular region
0.36	GO:0043195	terminal bouton
0.35	GO:0043025	neuronal cell body
0.33	GO:0005622	intracellular
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

sp|P10288|CADH2_CHICK
Cadherin-2
Search

CDH2

0.90	Cadherin 2, type 1 preproprotein (Predicted)

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.70	GO:0009966	regulation of signal transduction
0.59	GO:0044331	cell-cell adhesion mediated by cadherin
0.57	GO:1902897	regulation of postsynaptic density protein 95 clustering
0.57	GO:0097150	neuronal stem cell population maintenance
0.57	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly
0.56	GO:2000809	positive regulation of synaptic vesicle clustering
0.56	GO:0070445	regulation of oligodendrocyte progenitor proliferation
0.55	GO:0060019	radial glial cell differentiation
0.54	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

0.70	GO:0005509	calcium ion binding
0.55	GO:0045295	gamma-catenin binding
0.55	GO:0045294	alpha-catenin binding
0.53	GO:0019903	protein phosphatase binding
0.52	GO:0008013	beta-catenin binding
0.50	GO:0019901	protein kinase binding
0.48	GO:0042802	identical protein binding
0.35	GO:0050998	nitric-oxide synthase binding
0.35	GO:0050840	extracellular matrix binding
0.35	GO:0045296	cadherin binding

0.56	GO:0014704	intercalated disc
0.56	GO:0005886	plasma membrane
0.53	GO:0005913	cell-cell adherens junction
0.53	GO:0014069	postsynaptic density
0.52	GO:0030027	lamellipodium
0.51	GO:0098857	membrane microdomain
0.51	GO:0045177	apical part of cell
0.51	GO:0030864	cortical actin cytoskeleton
0.50	GO:0009986	cell surface
0.49	GO:0019898	extrinsic component of membrane

sp|P10360|P53_CHICK
Cellular tumor antigen p53
Search

TP53

0.84	Cellular tumor antigen p53

0.78	GO:0006915	apoptotic process
0.75	GO:0051262	protein tetramerization
0.66	GO:0007049	cell cycle
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0090200	positive regulation of release of cytochrome c from mitochondria
0.56	GO:0010468	regulation of gene expression
0.56	GO:0000733	DNA strand renaturation
0.56	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

0.76	GO:0044212	transcription regulatory region DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0001084	transcription factor activity, TFIID-class binding
0.54	GO:0002039	p53 binding
0.54	GO:0046872	metal ion binding
0.52	GO:0001094	TFIID-class transcription factor binding
0.52	GO:0035035	histone acetyltransferase binding
0.51	GO:0051721	protein phosphatase 2A binding
0.51	GO:0097718	disordered domain specific binding
0.51	GO:0047485	protein N-terminus binding

0.61	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.49	GO:0005737	cytoplasm
0.48	GO:0000785	chromatin
0.48	GO:0070013	intracellular organelle lumen
0.47	GO:0000428	DNA-directed RNA polymerase complex
0.42	GO:0005657	replication fork
0.42	GO:0012505	endomembrane system
0.36	GO:0035861	site of double-strand break
0.30	GO:0016020	membrane

sp|P10399|POL1_CHICK
Retrovirus-related Pol polyprotein (Fragments)
Search

0.55	Endogenous retrovirus group K member 11 Pol protein-like

0.70	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.69	GO:0015074	DNA integration

0.74	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding

0.74

EC:3.1.26.4

GO:0004523

sp|P10587|MYH11_CHICK
Myosin-11
Search

MYH11

0.73	Smooth muscle myosin heavy chain

0.73	GO:0007018	microtubule-based movement
0.42	GO:0048739	cardiac muscle fiber development
0.41	GO:0048251	elastic fiber assembly
0.41	GO:0030860	regulation of polarized epithelial cell differentiation
0.39	GO:0048546	digestive tract morphogenesis
0.39	GO:0060047	heart contraction
0.37	GO:0072593	reactive oxygen species metabolic process
0.34	GO:0030241	skeletal muscle myosin thick filament assembly
0.34	GO:0006939	smooth muscle contraction
0.34	GO:0034453	microtubule anchoring

0.74	GO:0051015	actin filament binding
0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0008307	structural constituent of muscle
0.33	GO:0005516	calmodulin binding
0.33	GO:0045159	myosin II binding
0.33	GO:0030898	actin-dependent ATPase activity

0.77	GO:0016459	myosin complex
0.33	GO:0044449	contractile fiber part
0.33	GO:0042470	melanosome
0.33	GO:0005815	microtubule organizing center
0.33	GO:0030016	myofibril
0.32	GO:0097517	contractile actin filament bundle
0.32	GO:0042641	actomyosin
0.32	GO:0005903	brush border
0.32	GO:0070062	extracellular exosome
0.31	GO:0005829	cytosol

sp|P10741|MOS_CHICK
Serine/threonine-protein kinase mos
Search

CMOS

0.53	Proto-oncogene serine/threonine-protein kinase mos

0.63	GO:0006468	protein phosphorylation
0.36	GO:1902103	negative regulation of metaphase/anaphase transition of meiotic cell cycle
0.35	GO:0000186	activation of MAPKK activity
0.33	GO:0035556	intracellular signal transduction

0.67	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005057	signal transducer activity, downstream of receptor

0.32

GO:0005737

cytoplasm

0.67

GO:0004674

sp|P11009|KCRS_CHICK
Creatine kinase S-type, mitochondrial
Search

CKMT2

0.97	Mitochondrial creatine kinase s-type

0.57	GO:0016310	phosphorylation
0.40	GO:0032091	negative regulation of protein binding
0.39	GO:0043066	negative regulation of apoptotic process
0.38	GO:0006600	creatine metabolic process
0.36	GO:0006599	phosphagen metabolic process
0.35	GO:0032501	multicellular organismal process
0.35	GO:0014706	striated muscle tissue development
0.35	GO:0061061	muscle structure development

0.59	GO:0016301	kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor
0.36	GO:1901612	cardiolipin binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.48	GO:0005739	mitochondrion
0.39	GO:0043209	myelin sheath
0.39	GO:0019866	organelle inner membrane
0.35	GO:0070062	extracellular exosome

0.41

EC:2.7.3

GO:0016775

sp|P11029|ACAC_CHICK
Acetyl-CoA carboxylase
Search

ACACA

0.46	Acetyl-CoA carboxylase alpha

0.69	GO:0006633	fatty acid biosynthetic process
0.53	GO:0044268	multicellular organismal protein metabolic process
0.52	GO:0071380	cellular response to prostaglandin E stimulus
0.51	GO:0051289	protein homotetramerization
0.50	GO:0001894	tissue homeostasis
0.49	GO:0055088	lipid homeostasis
0.47	GO:0035383	thioester metabolic process
0.43	GO:0006732	coenzyme metabolic process
0.40	GO:0006793	phosphorus metabolic process
0.38	GO:0044272	sulfur compound biosynthetic process

0.75	GO:0003989	acetyl-CoA carboxylase activity
0.75	GO:0004075	biotin carboxylase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.47	GO:0042802	identical protein binding
0.37	GO:0032810	sterol response element binding
0.37	GO:0050692	DBD domain binding
0.37	GO:0046966	thyroid hormone receptor binding

0.50	GO:0001650	fibrillar center
0.46	GO:0015629	actin cytoskeleton
0.45	GO:0005829	cytosol
0.41	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.75

EC:6.4.1.2

GO:0003989

sp|P11148|COL_CHICK
Colipase (Fragment)
Search

0.79	Colipase (Fragment)

0.84	GO:0007586	digestion
0.73	GO:0043085	positive regulation of catalytic activity
0.72	GO:0016042	lipid catabolic process
0.46	GO:0032094	response to food
0.44	GO:0050821	protein stabilization

0.75

GO:0008047

enzyme activator activity

0.66

GO:0005576

extracellular region

sp|P11183|GCSH_CHICK
Glycine cleavage system H protein, mitochondrial
Search

GCSH

0.46	Glycine cleavage system H protein, mitochondrial

0.76	GO:0019464	glycine decarboxylation via glycine cleavage system
0.42	GO:0009249	protein lipoylation
0.34	GO:0032259	methylation
0.32	GO:0034641	cellular nitrogen compound metabolic process

0.36	GO:0004047	aminomethyltransferase activity
0.35	GO:0005515	protein binding

0.78	GO:0005960	glycine cleavage complex
0.60	GO:0005739	mitochondrion
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.36

EC:2.1.2.10

GO:0004047

sp|P11501|HS90A_CHICK
Heat shock protein HSP 90-alpha
Search

HSP90AA1

0.87	Epididymis luminal secretory protein 52

0.69	GO:0006457	protein folding
0.68	GO:0009409	response to cold
0.63	GO:0009408	response to heat
0.63	GO:0046677	response to antibiotic
0.52	GO:1905323	telomerase holoenzyme complex assembly
0.50	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.50	GO:0051973	positive regulation of telomerase activity
0.50	GO:0007004	telomere maintenance via telomerase
0.49	GO:0045040	protein import into mitochondrial outer membrane
0.48	GO:0051131	chaperone-mediated protein complex assembly

0.71	GO:0051082	unfolded protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0030235	nitric-oxide synthase regulator activity
0.54	GO:0030911	TPR domain binding
0.51	GO:0070182	DNA polymerase binding
0.50	GO:0097110	scaffold protein binding
0.50	GO:0097718	disordered domain specific binding

0.53	GO:0005634	nucleus
0.48	GO:0032587	ruffle membrane
0.47	GO:0043209	myelin sheath
0.44	GO:0005737	cytoplasm
0.41	GO:0097708	intracellular vesicle
0.40	GO:0043234	protein complex
0.39	GO:0097226	sperm mitochondrial sheath
0.38	GO:0097524	sperm plasma membrane
0.38	GO:0043025	neuronal cell body
0.38	GO:0031526	brush border membrane

0.42

GO:0016887

sp|P11533|DMD_CHICK
Dystrophin
Search

DMD

0.70	Dystrophin

0.53	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
0.53	GO:0021629	olfactory nerve structural organization
0.53	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation
0.52	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
0.52	GO:0008065	establishment of blood-nerve barrier
0.52	GO:2000651	positive regulation of sodium ion transmembrane transporter activity
0.51	GO:0035994	response to muscle stretch
0.51	GO:0045213	neurotransmitter receptor metabolic process
0.51	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity
0.51	GO:0033137	negative regulation of peptidyl-serine phosphorylation

0.86	GO:0002162	dystroglycan binding
0.74	GO:0003779	actin binding
0.59	GO:0008270	zinc ion binding
0.52	GO:0050998	nitric-oxide synthase binding
0.42	GO:0017166	vinculin binding
0.42	GO:0005521	lamin binding
0.42	GO:0008307	structural constituent of muscle
0.41	GO:0030165	PDZ domain binding
0.41	GO:0005178	integrin binding
0.41	GO:0017022	myosin binding

0.64	GO:0045211	postsynaptic membrane
0.61	GO:0030054	cell junction
0.56	GO:0005856	cytoskeleton
0.51	GO:0042383	sarcolemma
0.49	GO:0044306	neuron projection terminus
0.49	GO:0030018	Z disc
0.49	GO:0016010	dystrophin-associated glycoprotein complex
0.48	GO:0098857	membrane microdomain
0.43	GO:0099617	matrix side of mitochondrial inner membrane
0.42	GO:0097449	astrocyte projection

sp|P11602|LIPL_CHICK
Lipoprotein lipase
Search

LPL

0.93	Lipoprotein lipase

0.70	GO:0016042	lipid catabolic process
0.58	GO:0009749	response to glucose
0.57	GO:0055096	low-density lipoprotein particle mediated signaling
0.56	GO:0010886	positive regulation of cholesterol storage
0.56	GO:0010890	positive regulation of sequestering of triglyceride
0.56	GO:0034372	very-low-density lipoprotein particle remodeling
0.55	GO:0090197	positive regulation of chemokine secretion
0.54	GO:0070328	triglyceride homeostasis
0.53	GO:0019432	triglyceride biosynthetic process
0.53	GO:0042632	cholesterol homeostasis

0.86	GO:0004465	lipoprotein lipase activity
0.80	GO:0008201	heparin binding
0.55	GO:0034185	apolipoprotein binding
0.48	GO:0005102	receptor binding
0.40	GO:0017129	triglyceride binding
0.35	GO:0004620	phospholipase activity

0.85	GO:0042627	chylomicron
0.84	GO:0034361	very-low-density lipoprotein particle
0.77	GO:0031225	anchored component of membrane
0.54	GO:0005886	plasma membrane
0.46	GO:0009986	cell surface
0.37	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.86

EC:3.1.1.34

GO:0004465

sp|P11682|APOB_CHICK
Apolipoprotein B (Fragment)
Search

0.37	Apolipoprotein B (Fragment)

0.74	GO:0006869	lipid transport
0.63	GO:0010886	positive regulation of cholesterol storage
0.63	GO:0045540	regulation of cholesterol biosynthetic process
0.62	GO:0034374	low-density lipoprotein particle remodeling
0.62	GO:0034383	low-density lipoprotein particle clearance
0.62	GO:0010744	positive regulation of macrophage derived foam cell differentiation
0.62	GO:0006642	triglyceride mobilization
0.62	GO:0019433	triglyceride catabolic process
0.61	GO:0008203	cholesterol metabolic process
0.60	GO:0048844	artery morphogenesis

0.76	GO:0005319	lipid transporter activity
0.63	GO:0035473	lipase binding
0.61	GO:0050750	low-density lipoprotein particle receptor binding
0.60	GO:0008201	heparin binding
0.54	GO:0005543	phospholipid binding

0.65	GO:0034362	low-density lipoprotein particle
0.65	GO:0034359	mature chylomicron
0.63	GO:0034361	very-low-density lipoprotein particle
0.63	GO:0034363	intermediate-density lipoprotein particle
0.61	GO:0070971	endoplasmic reticulum exit site
0.57	GO:0043025	neuronal cell body
0.50	GO:0005829	cytosol
0.39	GO:0031983	vesicle lumen
0.38	GO:0034360	chylomicron remnant
0.37	GO:0031904	endosome lumen

sp|P11722|FINC_CHICK
Fibronectin (Fragments)
Search

sp|P11799|MYLK_CHICK
Myosin light chain kinase, smooth muscle
Search

MYLK

0.72	Myosin light chain kinase

0.62	GO:0006468	protein phosphorylation
0.53	GO:0060414	aorta smooth muscle tissue morphogenesis
0.52	GO:0032060	bleb assembly
0.51	GO:2000145	regulation of cell motility
0.51	GO:0071476	cellular hypotonic response
0.51	GO:0051272	positive regulation of cellular component movement
0.51	GO:0040017	positive regulation of locomotion
0.51	GO:0090303	positive regulation of wound healing
0.50	GO:0051928	positive regulation of calcium ion transport
0.43	GO:0006939	smooth muscle contraction

0.62	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0005516	calmodulin binding
0.35	GO:0003779	actin binding
0.34	GO:0046872	metal ion binding

0.51	GO:0032154	cleavage furrow
0.50	GO:0097517	contractile actin filament bundle
0.50	GO:0042641	actomyosin
0.50	GO:0030027	lamellipodium
0.40	GO:0005886	plasma membrane
0.38	GO:0005829	cytosol
0.35	GO:0070062	extracellular exosome

sp|P11939|FOS_CHICK
Proto-oncogene c-Fos
Search

FOS

0.94	Proto-oncogene protein c-fos

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.61	GO:0035994	response to muscle stretch
0.61	GO:0045672	positive regulation of osteoclast differentiation
0.59	GO:0071277	cellular response to calcium ion
0.59	GO:0035914	skeletal muscle cell differentiation
0.59	GO:0071276	cellular response to cadmium ion
0.59	GO:0060395	SMAD protein signal transduction
0.57	GO:0007179	transforming growth factor beta receptor signaling pathway
0.54	GO:0006366	transcription by RNA polymerase II
0.53	GO:0034614	cellular response to reactive oxygen species

0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0070412	R-SMAD binding
0.59	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.59	GO:0001102	RNA polymerase II activating transcription factor binding
0.59	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0003682	chromatin binding
0.53	GO:0046982	protein heterodimerization activity
0.32	GO:0005198	structural molecule activity

0.73	GO:0005667	transcription factor complex
0.52	GO:0032993	protein-DNA complex
0.51	GO:0005654	nucleoplasm
0.42	GO:0005783	endoplasmic reticulum
0.41	GO:0005829	cytosol
0.38	GO:0043005	neuron projection
0.35	GO:0042025	host cell nucleus
0.33	GO:0019028	viral capsid
0.30	GO:0016020	membrane

sp|P12003|VINC_CHICK
Vinculin
Search

VCL

0.91	LOW QUALITY PROTEIN: vinculin

0.72	GO:0007155	cell adhesion
0.60	GO:0030032	lamellipodium assembly
0.59	GO:0034394	protein localization to cell surface
0.59	GO:0048675	axon extension
0.58	GO:0034333	adherens junction assembly
0.58	GO:0043297	apical junction assembly
0.55	GO:0030334	regulation of cell migration
0.55	GO:0002009	morphogenesis of an epithelium
0.48	GO:0099622	cardiac muscle cell membrane repolarization
0.48	GO:0086011	membrane repolarization during action potential

0.78	GO:0051015	actin filament binding
0.62	GO:0005198	structural molecule activity
0.60	GO:0045294	alpha-catenin binding
0.59	GO:0002162	dystroglycan binding
0.56	GO:0045296	cadherin binding
0.55	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0051371	muscle alpha-actinin binding
0.47	GO:0017166	vinculin binding
0.46	GO:0097110	scaffold protein binding
0.43	GO:0042803	protein homodimerization activity

0.74	GO:0015629	actin cytoskeleton
0.61	GO:0043034	costamere
0.61	GO:0005916	fascia adherens
0.59	GO:0042383	sarcolemma
0.58	GO:0005925	focal adhesion
0.52	GO:0044430	cytoskeletal part
0.51	GO:0090636	outer dense plaque of desmosome
0.48	GO:0098723	skeletal muscle myofibril
0.47	GO:0090637	inner dense plaque of desmosome
0.47	GO:0005927	muscle tendon junction

sp|P12105|CO3A1_CHICK
Collagen alpha-1(III) chain (Fragments)
Search

COL3A1

0.78	Collagen type III alpha 1 chain

0.59	GO:0030199	collagen fibril organization
0.58	GO:0060414	aorta smooth muscle tissue morphogenesis
0.58	GO:2001223	negative regulation of neuron migration
0.57	GO:0043588	skin development
0.56	GO:0071230	cellular response to amino acid stimulus
0.56	GO:0035025	positive regulation of Rho protein signal transduction
0.56	GO:0018149	peptide cross-linking
0.55	GO:0071560	cellular response to transforming growth factor beta stimulus
0.55	GO:0021987	cerebral cortex development
0.55	GO:0007160	cell-matrix adhesion

0.78	GO:0005201	extracellular matrix structural constituent
0.61	GO:0048407	platelet-derived growth factor binding
0.58	GO:0002020	protease binding
0.56	GO:0005178	integrin binding
0.54	GO:0046332	SMAD binding
0.40	GO:0042802	identical protein binding
0.36	GO:0042289	MHC class II protein binding
0.35	GO:0046872	metal ion binding

0.71	GO:0005581	collagen trimer
0.61	GO:0098643	banded collagen fibril
0.52	GO:0005615	extracellular space
0.37	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0005604	basement membrane
0.35	GO:0030141	secretory granule
0.34	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

sp|P12106|CO9A1_CHICK
Collagen alpha-1(IX) chain
Search

COL9A1

0.91	Collagen type IX alpha 1 chain

0.39	GO:0003417	growth plate cartilage development
0.38	GO:0001894	tissue homeostasis
0.37	GO:0002062	chondrocyte differentiation
0.35	GO:0030198	extracellular matrix organization

0.37	GO:0030020	extracellular matrix structural constituent conferring tensile strength
0.34	GO:0046872	metal ion binding

0.78	GO:0005581	collagen trimer
0.39	GO:0005578	proteinaceous extracellular matrix
0.35	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

sp|P12108|CO9A2_CHICK
Collagen alpha-2(IX) chain
Search

COL9A2

0.88	Collagen type VIII alpha 1 chain

0.53	GO:0035989	tendon development
0.52	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
0.51	GO:0035987	endodermal cell differentiation
0.51	GO:0001502	cartilage condensation
0.51	GO:0002063	chondrocyte development
0.50	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.50	GO:0030199	collagen fibril organization
0.50	GO:0042472	inner ear morphogenesis
0.49	GO:0006029	proteoglycan metabolic process
0.49	GO:0048704	embryonic skeletal system morphogenesis

0.62	GO:0005201	extracellular matrix structural constituent
0.35	GO:0050840	extracellular matrix binding
0.34	GO:0030674	protein binding, bridging
0.34	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0046872	metal ion binding

0.72	GO:0005581	collagen trimer
0.52	GO:0098643	banded collagen fibril
0.46	GO:0005615	extracellular space
0.36	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016020	membrane

sp|P12244|GSBP_CHICK
Dolichyl-diphosphooligosaccharide--protein glycotransferase
Search

P4HB

0.48	Dolichyl-diphosphooligosaccharide--protein glycotransferase

0.68	GO:0045454	cell redox homeostasis
0.57	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.56	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline
0.55	GO:0046598	positive regulation of viral entry into host cell
0.53	GO:0034976	response to endoplasmic reticulum stress
0.53	GO:0071456	cellular response to hypoxia
0.42	GO:0006457	protein folding
0.41	GO:0055114	oxidation-reduction process
0.36	GO:0034378	chylomicron assembly
0.36	GO:0038155	interleukin-23-mediated signaling pathway

0.79	GO:0003756	protein disulfide isomerase activity
0.56	GO:0031545	peptidyl-proline 4-dioxygenase activity
0.53	GO:0019798	procollagen-proline dioxygenase activity
0.53	GO:0005178	integrin binding
0.51	GO:0015037	peptide disulfide oxidoreductase activity
0.50	GO:0046982	protein heterodimerization activity
0.37	GO:0019899	enzyme binding
0.34	GO:0003723	RNA binding
0.32	GO:0016740	transferase activity

0.69	GO:0005783	endoplasmic reticulum
0.52	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.52	GO:0009897	external side of plasma membrane
0.46	GO:1990204	oxidoreductase complex
0.43	GO:0044446	intracellular organelle part
0.43	GO:0042470	melanosome
0.43	GO:0043234	protein complex
0.40	GO:0043233	organelle lumen
0.37	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion

0.79

EC:5.3.4.1

GO:0003756

sp|P12264|41_CHICK
Erythroid protein 4.1 (Fragment)
Search

0.48	Erythroid protein 4.1 (Fragment)

0.87	GO:1904778	positive regulation of protein localization to cell cortex
0.74	GO:0030036	actin cytoskeleton organization
0.69	GO:0032092	positive regulation of protein binding
0.68	GO:0030865	cortical cytoskeleton organization
0.58	GO:0008360	regulation of cell shape
0.56	GO:0051301	cell division
0.56	GO:0007049	cell cycle

0.74	GO:0003779	actin binding
0.70	GO:0047485	protein N-terminus binding
0.69	GO:0051219	phosphoprotein binding
0.68	GO:0005545	1-phosphatidylinositol binding
0.68	GO:0008022	protein C-terminus binding
0.65	GO:0005516	calmodulin binding
0.63	GO:0005200	structural constituent of cytoskeleton

0.83	GO:0099738	cell cortex region
0.69	GO:0005856	cytoskeleton
0.62	GO:0030054	cell junction
0.57	GO:0005829	cytosol
0.56	GO:0005886	plasma membrane
0.52	GO:0005634	nucleus
0.51	GO:0043234	protein complex

sp|P12274|HMGN1_CHICK
Non-histone chromosomal protein HMG-14B
Search

HMGN1

0.91	Non-histone chromosomal protein HMG-14

0.42	GO:0048597	post-embryonic camera-type eye morphogenesis
0.42	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair
0.42	GO:1901666	positive regulation of NAD+ ADP-ribosyltransferase activity
0.41	GO:0010225	response to UV-C
0.41	GO:0040034	regulation of development, heterochronic
0.41	GO:0010224	response to UV-B
0.40	GO:0050678	regulation of epithelial cell proliferation
0.39	GO:0006283	transcription-coupled nucleotide-excision repair
0.39	GO:0006357	regulation of transcription by RNA polymerase II
0.38	GO:0006325	chromatin organization

0.85	GO:0031492	nucleosomal DNA binding
0.34	GO:0005515	protein binding

0.72	GO:0000785	chromatin
0.61	GO:0005634	nucleus
0.36	GO:0031974	membrane-enclosed lumen
0.34	GO:0005737	cytoplasm

sp|P12275|ARYL_CHICK
Arylamine N-acetyltransferase, liver isozyme
Search

0.92	Arylamine N-acetyltransferase, liver isozyme

0.36	GO:0097068	response to thyroxine
0.35	GO:1902475	L-alpha-amino acid transmembrane transport
0.35	GO:0001889	liver development
0.35	GO:0007568	aging
0.34	GO:0048565	digestive tract development
0.34	GO:0032496	response to lipopolysaccharide
0.34	GO:0001666	response to hypoxia
0.33	GO:0009410	response to xenobiotic stimulus
0.32	GO:0055114	oxidation-reduction process

0.67	GO:0016407	acetyltransferase activity
0.42	GO:0016410	N-acyltransferase activity
0.35	GO:0015179	L-amino acid transmembrane transporter activity
0.32	GO:0016491	oxidoreductase activity

0.34	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.67

GO:0016407

sp|P12276|FAS_CHICK
Fatty acid synthase
Search

FASN

0.74	Fatty acid synthase

0.55	GO:0071353	cellular response to interleukin-4
0.51	GO:0055114	oxidation-reduction process
0.50	GO:0030879	mammary gland development
0.48	GO:0006633	fatty acid biosynthetic process
0.39	GO:0032100	positive regulation of appetite
0.37	GO:0006089	lactate metabolic process
0.37	GO:0001649	osteoblast differentiation
0.37	GO:0006084	acetyl-CoA metabolic process
0.35	GO:0030223	neutrophil differentiation
0.35	GO:0030224	monocyte differentiation

0.84	GO:0004317	3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
0.84	GO:0004313	[acyl-carrier-protein] S-acetyltransferase activity
0.83	GO:0016295	myristoyl-[acyl-carrier-protein] hydrolase activity
0.83	GO:0016296	palmitoyl-[acyl-carrier-protein] hydrolase activity
0.83	GO:0004320	oleoyl-[acyl-carrier-protein] hydrolase activity
0.82	GO:0004319	enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity
0.76	GO:0004314	[acyl-carrier-protein] S-malonyltransferase activity
0.74	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
0.74	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity
0.72	GO:0031177	phosphopantetheine binding

0.57	GO:0042587	glycogen granule
0.48	GO:0005794	Golgi apparatus
0.47	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.41	GO:0005886	plasma membrane
0.39	GO:0042470	melanosome
0.36	GO:0070062	extracellular exosome

0.84	EC:4.2.1.61	GO:0004317
0.84	KEGG:R04462	GO:0004317

sp|P12394|CP17A_CHICK
Steroid 17-alpha-hydroxylase/17,20 lyase
Search

CYP17A1

0.92	Steroid 17-alpha-hydroxylase

0.73	GO:0007548	sex differentiation
0.72	GO:0006694	steroid biosynthetic process
0.59	GO:0042448	progesterone metabolic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0042446	hormone biosynthetic process
0.48	GO:0008211	glucocorticoid metabolic process
0.43	GO:0042181	ketone biosynthetic process
0.35	GO:0018879	biphenyl metabolic process
0.35	GO:0018963	phthalate metabolic process
0.35	GO:1901615	organic hydroxy compound metabolic process

0.85	GO:0004508	steroid 17-alpha-monooxygenase activity
0.85	GO:0047442	17-alpha-hydroxyprogesterone aldolase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.48	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003677	DNA binding

0.45	GO:0043025	neuronal cell body
0.45	GO:0030424	axon
0.39	GO:0005739	mitochondrion
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.85

EC:1.14.99.9

GO:0004508

sp|P12620|TNNT3_CHICK
Troponin T, fast skeletal muscle isoforms
Search

TNNT3

0.92	Troponin T fast skeletal muscle type

0.85	GO:0006942	regulation of striated muscle contraction
0.50	GO:0003009	skeletal muscle contraction
0.47	GO:0043462	regulation of ATPase activity
0.35	GO:0030049	muscle filament sliding
0.34	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process

0.52	GO:0030899	calcium-dependent ATPase activity
0.52	GO:0030172	troponin C binding
0.52	GO:0031013	troponin I binding
0.50	GO:0048306	calcium-dependent protein binding
0.49	GO:0005523	tropomyosin binding
0.45	GO:0003779	actin binding
0.35	GO:0031014	troponin T binding
0.34	GO:0003735	structural constituent of ribosome

0.83	GO:0005861	troponin complex
0.34	GO:0005840	ribosome
0.33	GO:0005829	cytosol

sp|P12902|HM14A_CHICK
Non-histone chromosomal protein HMG-14A
Search

HMGN2

0.93	high mobility group nucleosome-binding domain-containing protein 5

0.35	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.35	GO:0040034	regulation of development, heterochronic
0.34	GO:0031640	killing of cells of other organism
0.34	GO:0000122	negative regulation of transcription by RNA polymerase II

0.85	GO:0031492	nucleosomal DNA binding
0.33	GO:0003723	RNA binding
0.32	GO:0005515	protein binding

0.72	GO:0000785	chromatin
0.61	GO:0005634	nucleus
0.34	GO:0005615	extracellular space
0.33	GO:0005737	cytoplasm

sp|P12957|CALD1_CHICK
Caldesmon
Search

CALD1

0.88	Non-muscle caldesmon

0.83	GO:0006936	muscle contraction
0.41	GO:0006940	regulation of smooth muscle contraction
0.41	GO:1903611	negative regulation of calcium-dependent ATPase activity
0.36	GO:0043393	regulation of protein binding
0.35	GO:0071559	response to transforming growth factor beta
0.35	GO:0006508	proteolysis
0.34	GO:0051100	negative regulation of binding
0.34	GO:0007565	female pregnancy
0.34	GO:0051099	positive regulation of binding
0.34	GO:0051017	actin filament bundle assembly

0.85	GO:0017022	myosin binding
0.79	GO:0005516	calmodulin binding
0.74	GO:0003779	actin binding
0.51	GO:0045296	cadherin binding
0.37	GO:0044548	S100 protein binding
0.37	GO:0004181	metallocarboxypeptidase activity
0.35	GO:0008270	zinc ion binding
0.34	GO:0005523	tropomyosin binding
0.34	GO:0032403	protein complex binding

0.55	GO:0030478	actin cap
0.41	GO:0005886	plasma membrane
0.41	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0030016	myofibril
0.35	GO:0005884	actin filament
0.34	GO:0043197	dendritic spine
0.34	GO:0014069	postsynaptic density
0.34	GO:0043025	neuronal cell body
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.37

EC:3.4.17

GO:0004181

sp|P13127|CAZA1_CHICK
F-actin-capping protein subunit alpha-1
Search

CAPZA1

0.81	Capping actin protein of muscle Z-line alpha subunit 1

0.84	GO:0051016	barbed-end actin filament capping
0.59	GO:0034329	cell junction assembly

0.74	GO:0003779	actin binding
0.59	GO:0045296	cadherin binding

0.84	GO:0008290	F-actin capping protein complex
0.60	GO:0071203	WASH complex
0.47	GO:0005903	brush border
0.46	GO:0030863	cortical cytoskeleton
0.30	GO:0016020	membrane

sp|P13216|ADX_CHICK
Adrenodoxin, mitochondrial (Fragment)
Search

FDX1

0.60	Adrenodoxin, mitochondrial

0.61	GO:0022900	electron transport chain
0.54	GO:1904321	response to forskolin
0.53	GO:0071320	cellular response to cAMP
0.52	GO:1901655	cellular response to ketone
0.52	GO:0008203	cholesterol metabolic process
0.50	GO:0035690	cellular response to drug
0.50	GO:0042446	hormone biosynthetic process
0.49	GO:0071396	cellular response to lipid
0.44	GO:1904087	negative regulation of epiboly involved in gastrulation with mouth forming second
0.40	GO:0006694	steroid biosynthetic process

0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.62	GO:0009055	electron transfer activity
0.35	GO:0046872	metal ion binding
0.35	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity
0.35	GO:0015039	NADPH-adrenodoxin reductase activity
0.34	GO:0008022	protein C-terminus binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0019899	enzyme binding

0.43	GO:0005739	mitochondrion
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.33	GO:0031090	organelle membrane
0.33	GO:0031975	envelope
0.30	GO:0044425	membrane part

0.35

EC:1.14.15.6

GO:0008386

sp|P13387|EGFR_CHICK
Epidermal growth factor receptor (Fragment)
Search

EGFR

0.69	Epidermal growth factor receptor

0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.59	GO:0071364	cellular response to epidermal growth factor stimulus
0.56	GO:0007611	learning or memory
0.54	GO:0071392	cellular response to estradiol stimulus
0.53	GO:1902722	positive regulation of prolactin secretion
0.52	GO:0033590	response to cobalamin
0.52	GO:0033594	response to hydroxyisoflavone
0.52	GO:0010750	positive regulation of nitric oxide mediated signal transduction
0.52	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.58	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.52	GO:0048408	epidermal growth factor binding
0.51	GO:0030235	nitric-oxide synthase regulator activity
0.49	GO:0003682	chromatin binding
0.48	GO:0005178	integrin binding

0.54	GO:0031965	nuclear membrane
0.54	GO:0010008	endosome membrane
0.52	GO:0097489	multivesicular body, internal vesicle lumen
0.52	GO:0000139	Golgi membrane
0.51	GO:0005789	endoplasmic reticulum membrane
0.48	GO:0016323	basolateral plasma membrane
0.47	GO:0016324	apical plasma membrane
0.47	GO:0030139	endocytic vesicle
0.47	GO:0098857	membrane microdomain
0.47	GO:0005769	early endosome

0.80	EC:2.7.10.1	GO:0004714
0.45	KEGG:R04545	GO:0046934

sp|P13474|ETS1A_CHICK
Transforming protein p54/c-ets-1
Search

ETS1

0.72	ETS proto-oncogene 1, transcription factor

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0030578	PML body organization
0.55	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell
0.54	GO:0061614	pri-miRNA transcription by RNA polymerase II
0.54	GO:0045648	positive regulation of erythrocyte differentiation
0.53	GO:0010595	positive regulation of endothelial cell migration
0.52	GO:0043535	regulation of blood vessel endothelial cell migration
0.51	GO:0045765	regulation of angiogenesis

0.65	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.49	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0042802	identical protein binding
0.47	GO:0003690	double-stranded DNA binding
0.40	GO:0035035	histone acetyltransferase binding
0.34	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.44	GO:0043233	organelle lumen
0.41	GO:0044446	intracellular organelle part
0.33	GO:0042025	host cell nucleus
0.33	GO:0005737	cytoplasm

sp|P13538|MYSS_CHICK
Myosin heavy chain, skeletal muscle, adult
Search

0.72	Fast myosin heavy chain HCIII

0.74	GO:0007018	microtubule-based movement
0.51	GO:0014823	response to activity
0.50	GO:0006936	muscle contraction
0.44	GO:0070252	actin-mediated cell contraction
0.41	GO:0001778	plasma membrane repair
0.39	GO:0050881	musculoskeletal movement
0.37	GO:0031034	myosin filament assembly
0.36	GO:0046034	ATP metabolic process
0.35	GO:0035994	response to muscle stretch
0.35	GO:0009629	response to gravity

0.78	GO:0051015	actin filament binding
0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0005516	calmodulin binding
0.45	GO:0000146	microfilament motor activity
0.39	GO:0003725	double-stranded RNA binding
0.37	GO:0016887	ATPase activity

0.77	GO:0016459	myosin complex
0.57	GO:0043292	contractile fiber
0.47	GO:0014704	intercalated disc
0.45	GO:0036464	cytoplasmic ribonucleoprotein granule
0.40	GO:0005826	actomyosin contractile ring
0.38	GO:0005794	Golgi apparatus
0.33	GO:0005829	cytosol

0.37

GO:0016887

sp|P13544|HXD1_CHICK
Homeobox protein Hox-D1 (Fragment)
Search

HOXD1

0.77	Homeobox protein Hox-D1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0048706	embryonic skeletal system development
0.52	GO:0007399	nervous system development
0.50	GO:0060322	head development
0.50	GO:0003002	regionalization
0.49	GO:0048857	neural nucleus development
0.49	GO:0048532	anatomical structure arrangement
0.48	GO:0048513	animal organ development

0.65	GO:0043565	sequence-specific DNA binding
0.48	GO:0044212	transcription regulatory region DNA binding
0.48	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0019904	protein domain specific binding
0.44	GO:0003690	double-stranded DNA binding
0.42	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.40	GO:0046982	protein heterodimerization activity
0.33	GO:0004743	pyruvate kinase activity
0.33	GO:0030955	potassium ion binding
0.33	GO:0016301	kinase activity

0.61	GO:0005634	nucleus
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm

0.33

EC:2.7.1.40

GO:0004743

sp|P13585|AT2A1_CHICK
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
Search

ATP2A1

0.56	Calcium-transporting ATPase

0.76	GO:0070588	calcium ion transmembrane transport
0.68	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.60	GO:0032470	positive regulation of endoplasmic reticulum calcium ion concentration
0.58	GO:0090257	regulation of muscle system process
0.56	GO:0003012	muscle system process
0.51	GO:0051659	maintenance of mitochondrion location
0.51	GO:1903233	regulation of calcium ion-dependent exocytosis of neurotransmitter
0.51	GO:0033292	T-tubule organization
0.51	GO:0070296	sarcoplasmic reticulum calcium ion transport
0.51	GO:0051241	negative regulation of multicellular organismal process

0.80	GO:0005388	calcium-transporting ATPase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0005509	calcium ion binding
0.49	GO:0044548	S100 protein binding
0.45	GO:0042803	protein homodimerization activity
0.44	GO:0019899	enzyme binding
0.39	GO:0031775	lutropin-choriogonadotropic hormone receptor binding

0.59	GO:0016529	sarcoplasmic reticulum
0.52	GO:0005789	endoplasmic reticulum membrane
0.50	GO:0097470	ribbon synapse
0.47	GO:0098588	bounding membrane of organelle
0.45	GO:0031673	H zone
0.43	GO:0005654	nucleoplasm
0.43	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.43	GO:0031674	I band
0.40	GO:0005739	mitochondrion

0.80

EC:3.6.3.8

GO:0005388

sp|P13590|NCAM1_CHICK
Neural cell adhesion molecule 1
Search

NCAM1

0.91	Neural cell adhesion molecule 1-A

0.72	GO:0007155	cell adhesion
0.38	GO:0001928	regulation of exocyst assembly
0.37	GO:0031175	neuron projection development
0.37	GO:0050850	positive regulation of calcium-mediated signaling
0.36	GO:0007166	cell surface receptor signaling pathway
0.35	GO:0010288	response to lead ion
0.35	GO:0021794	thalamus development
0.35	GO:0051930	regulation of sensory perception of pain
0.35	GO:0060045	positive regulation of cardiac muscle cell proliferation
0.35	GO:0010033	response to organic substance

0.36	GO:0008201	heparin binding
0.36	GO:0042802	identical protein binding
0.35	GO:0030275	LRR domain binding
0.35	GO:0104005	hijacked molecular function
0.35	GO:0019899	enzyme binding
0.34	GO:0005104	fibroblast growth factor receptor binding
0.33	GO:0008092	cytoskeletal protein binding
0.33	GO:0098772	molecular function regulator

0.47	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.36	GO:0009986	cell surface
0.36	GO:0030426	growth cone
0.36	GO:0098552	side of membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0043209	myelin sheath
0.36	GO:0043025	neuronal cell body
0.36	GO:0030424	axon
0.36	GO:0031225	anchored component of membrane

sp|P13648|LMNA_CHICK
Lamin-A
Search

LMNA

0.95	Nuclear lamin A

0.60	GO:0035105	sterol regulatory element binding protein import into nucleus
0.59	GO:1903243	negative regulation of cardiac muscle hypertrophy in response to stress
0.59	GO:0090342	regulation of cell aging
0.58	GO:0072201	negative regulation of mesenchymal cell proliferation
0.57	GO:0055015	ventricular cardiac muscle cell development
0.57	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.56	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity
0.55	GO:0071456	cellular response to hypoxia
0.55	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.55	GO:0006998	nuclear envelope organization

0.62	GO:0005198	structural molecule activity
0.37	GO:0042802	identical protein binding
0.35	GO:0008157	protein phosphatase 1 binding
0.32	GO:0003676	nucleic acid binding

0.79	GO:0005882	intermediate filament
0.57	GO:0005652	nuclear lamina
0.52	GO:0031965	nuclear membrane
0.49	GO:0005654	nucleoplasm
0.38	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0031012	extracellular matrix
0.35	GO:0016363	nuclear matrix
0.34	GO:0005829	cytosol
0.34	GO:0019031	viral envelope

sp|P13724|NEUT_CHICK
Neurotensin
Search

0.10	Neurotensin

0.30

GO:0050880

regulation of blood vessel size

0.30

GO:0005576

extracellular region

sp|P13731|SERPH_CHICK
Serpin H1
Search

SERPINH1

0.97	Serpin peptidase inhibitor clade H member 1

0.76	GO:0010951	negative regulation of endopeptidase activity
0.56	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis
0.56	GO:0032964	collagen biosynthetic process
0.56	GO:0030199	collagen fibril organization
0.48	GO:0051604	protein maturation
0.46	GO:0031101	fin regeneration
0.35	GO:0006986	response to unfolded protein

0.83	GO:0005518	collagen binding
0.79	GO:0004867	serine-type endopeptidase inhibitor activity
0.47	GO:0051082	unfolded protein binding
0.34	GO:0003723	RNA binding

0.73	GO:0005615	extracellular space
0.55	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.53	GO:0045121	membrane raft
0.52	GO:0005783	endoplasmic reticulum
0.40	GO:0005581	collagen trimer
0.38	GO:0043233	organelle lumen
0.36	GO:1903561	extracellular vesicle
0.36	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

sp|P13854|MGF_CHICK
Myelomonocytic growth factor
Search

CSF3

0.81	Myelomonocytic growth factor

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.67	GO:0030223	neutrophil differentiation
0.66	GO:0030225	macrophage differentiation
0.66	GO:2000251	positive regulation of actin cytoskeleton reorganization
0.65	GO:0042993	positive regulation of transcription factor import into nucleus
0.64	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.64	GO:0061515	myeloid cell development
0.64	GO:0051897	positive regulation of protein kinase B signaling
0.64	GO:0045639	positive regulation of myeloid cell differentiation

0.81	GO:0005125	cytokine activity
0.70	GO:0005130	granulocyte colony-stimulating factor receptor binding
0.59	GO:0008083	growth factor activity
0.55	GO:0019899	enzyme binding

0.66

GO:0005576

extracellular region

sp|P13863|CDK1_CHICK
Cyclin-dependent kinase 1
Search

CDK1

0.87	LOW QUALITY PROTEIN: cyclin-dependent kinase 1

0.63	GO:0006468	protein phosphorylation
0.55	GO:1905448	positive regulation of mitochondrial ATP synthesis coupled electron transport
0.53	GO:0051726	regulation of cell cycle
0.52	GO:0044772	mitotic cell cycle phase transition
0.52	GO:0034501	protein localization to kinetochore
0.51	GO:0018210	peptidyl-threonine modification
0.51	GO:1900182	positive regulation of protein localization to nucleus
0.50	GO:0018209	peptidyl-serine modification
0.50	GO:0016570	histone modification
0.49	GO:0030855	epithelial cell differentiation

0.66	GO:0004674	protein serine/threonine kinase activity
0.58	GO:0097472	cyclin-dependent protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0035173	histone kinase activity
0.52	GO:0030544	Hsp70 protein binding
0.51	GO:0030332	cyclin binding
0.48	GO:0003682	chromatin binding

0.55	GO:0097125	cyclin B1-CDK1 complex
0.53	GO:0072686	mitotic spindle
0.51	GO:0030496	midbody
0.50	GO:0005876	spindle microtubule
0.50	GO:0005815	microtubule organizing center
0.48	GO:0005759	mitochondrial matrix
0.46	GO:0005829	cytosol
0.46	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.36	GO:0000781	chromosome, telomeric region

0.66

GO:0004674

sp|P13913|ARY1_CHICK
Arylamine N-acetyltransferase, pineal gland isozyme NAT-10
Search

0.86	Arylamine N-acetyltransferase, pineal gland isozyme NAT-3

0.35	GO:0009410	response to xenobiotic stimulus
0.34	GO:0048565	digestive tract development
0.34	GO:0032496	response to lipopolysaccharide
0.34	GO:0001666	response to hypoxia
0.33	GO:0070887	cellular response to chemical stimulus
0.32	GO:0055114	oxidation-reduction process
0.30	GO:0044237	cellular metabolic process

0.67	GO:0016407	acetyltransferase activity
0.40	GO:0016410	N-acyltransferase activity
0.32	GO:0016491	oxidoreductase activity

0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.67

GO:0016407

sp|P13914|ARY2_CHICK
Arylamine N-acetyltransferase, pineal gland isozyme NAT-3
Search

0.87	Arylamine N-acetyltransferase, liver isozyme

0.38	GO:0097068	response to thyroxine
0.36	GO:0001889	liver development
0.36	GO:0007568	aging
0.35	GO:1902475	L-alpha-amino acid transmembrane transport
0.35	GO:0009410	response to xenobiotic stimulus
0.34	GO:0048565	digestive tract development
0.34	GO:0032496	response to lipopolysaccharide
0.34	GO:0001666	response to hypoxia
0.33	GO:0070887	cellular response to chemical stimulus
0.32	GO:0055114	oxidation-reduction process

0.67	GO:0016407	acetyltransferase activity
0.42	GO:0016410	N-acyltransferase activity
0.35	GO:0015179	L-amino acid transmembrane transporter activity
0.32	GO:0016491	oxidoreductase activity

0.36	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.67

GO:0016407

sp|P13944|COCA1_CHICK
Collagen alpha-1(XII) chain
Search

0.63	Collagen type XII alpha 1 chain

0.46	GO:0035987	endodermal cell differentiation
0.34	GO:0007155	cell adhesion
0.33	GO:0030574	collagen catabolic process
0.33	GO:0030199	collagen fibril organization
0.33	GO:0001501	skeletal system development

0.34

GO:0030020

extracellular matrix structural constituent conferring tensile strength

0.77	GO:0005581	collagen trimer
0.43	GO:0031012	extracellular matrix
0.42	GO:0005615	extracellular space
0.33	GO:0005788	endoplasmic reticulum lumen
0.33	GO:1903561	extracellular vesicle
0.30	GO:0044425	membrane part

sp|P14092|ATP6_CHICK
ATP synthase subunit a
Search

ATP6

0.42	ATP synthase subunit a

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.34	GO:0016887	ATPase activity

0.72	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.36	GO:0098798	mitochondrial protein complex
0.30	GO:0016021	integral component of membrane

0.34

GO:0016887

sp|P14093|ATP8_CHICK
ATP synthase protein 8
Search

ATP8

0.48	ATP synthase protein 8

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process

0.63

GO:0015078

hydrogen ion transmembrane transporter activity

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.30	GO:0016021	integral component of membrane

sp|P14105|MYH9_CHICK
Myosin-9
Search

MYH9

0.91	Nonmuscle myosin II heavy chain A

0.73	GO:0007018	microtubule-based movement
0.60	GO:1903923	positive regulation of protein processing in phagocytic vesicle
0.60	GO:1903919	negative regulation of actin filament severing
0.57	GO:0032796	uropod organization
0.57	GO:0006911	phagocytosis, engulfment
0.56	GO:0001768	establishment of T cell polarity
0.56	GO:1903131	mononuclear cell differentiation
0.56	GO:0051295	establishment of meiotic spindle localization
0.56	GO:0030220	platelet formation
0.56	GO:0043534	blood vessel endothelial cell migration

0.75	GO:0051015	actin filament binding
0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.56	GO:0000146	microfilament motor activity
0.56	GO:0030898	actin-dependent ATPase activity
0.55	GO:0043495	protein membrane anchor
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.77	GO:0016459	myosin complex
0.56	GO:0001931	uropod
0.55	GO:0001725	stress fiber
0.55	GO:0001772	immunological synapse
0.54	GO:0005925	focal adhesion
0.54	GO:0032154	cleavage furrow
0.54	GO:0005826	actomyosin contractile ring
0.53	GO:0001726	ruffle
0.53	GO:0031594	neuromuscular junction
0.53	GO:0005903	brush border

0.35

GO:0005391

sp|P14154|CXA1_CHICK
Gap junction alpha-1 protein
Search

GJA1

0.65	Gap junction alpha-1 protein (Fragment)

0.79	GO:0007507	heart development
0.74	GO:0007267	cell-cell signaling
0.55	GO:0010644	cell communication by electrical coupling
0.55	GO:0055085	transmembrane transport
0.51	GO:0060156	milk ejection reflex
0.51	GO:0010643	cell communication by chemical coupling
0.50	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization
0.50	GO:0030308	negative regulation of cell growth
0.50	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization
0.49	GO:0002070	epithelial cell maturation

0.57	GO:0022857	transmembrane transporter activity
0.48	GO:0097110	scaffold protein binding
0.48	GO:1990782	protein tyrosine kinase binding
0.47	GO:0048487	beta-tubulin binding
0.44	GO:0004871	signal transducer activity
0.44	GO:0005102	receptor binding
0.39	GO:0030165	PDZ domain binding
0.38	GO:0071253	connexin binding
0.38	GO:0017124	SH3 domain binding
0.38	GO:0097718	disordered domain specific binding

0.83	GO:0005922	connexin complex
0.56	GO:0014704	intercalated disc
0.48	GO:0016328	lateral plasma membrane
0.47	GO:0005913	cell-cell adherens junction
0.47	GO:0016324	apical plasma membrane
0.46	GO:0005654	nucleoplasm
0.46	GO:0043292	contractile fiber
0.46	GO:0005882	intermediate filament
0.44	GO:0012505	endomembrane system
0.43	GO:0005739	mitochondrion

sp|P14315|CAPZB_CHICK
F-actin-capping protein subunit beta isoforms 1 and 2
Search

CAPZB

0.72	F-actin-capping protein subunit beta

0.84	GO:0051016	barbed-end actin filament capping
0.73	GO:0030036	actin cytoskeleton organization
0.47	GO:0051490	negative regulation of filopodium assembly
0.46	GO:0010591	regulation of lamellipodium assembly
0.45	GO:0031115	negative regulation of microtubule polymerization
0.44	GO:0090036	regulation of protein kinase C signaling
0.44	GO:0030032	lamellipodium assembly
0.43	GO:0048747	muscle fiber development
0.42	GO:0031175	neuron projection development
0.41	GO:0022604	regulation of cell morphogenesis

0.73	GO:0003779	actin binding
0.44	GO:0032403	protein complex binding
0.43	GO:0048487	beta-tubulin binding
0.40	GO:0045296	cadherin binding

0.84	GO:0008290	F-actin capping protein complex
0.49	GO:0005737	cytoplasm
0.44	GO:0005884	actin filament
0.44	GO:0014704	intercalated disc
0.43	GO:0005903	brush border
0.43	GO:0097223	sperm part
0.43	GO:0030027	lamellipodium
0.41	GO:0031982	vesicle
0.39	GO:0012505	endomembrane system
0.38	GO:0043230	extracellular organelle

sp|P14448|FIBA_CHICK
Fibrinogen alpha chain
Search

FGA

0.69	LOW QUALITY PROTEIN: fibrinogen alpha chain

0.82	GO:0007596	blood coagulation
0.74	GO:0001775	cell activation
0.72	GO:0051258	protein polymerization
0.57	GO:0007165	signal transduction
0.51	GO:0043152	induction of bacterial agglutination
0.50	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.50	GO:0042730	fibrinolysis
0.50	GO:0072376	protein activation cascade
0.50	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.50	GO:0045907	positive regulation of vasoconstriction

0.75	GO:0030674	protein binding, bridging
0.68	GO:0005102	receptor binding
0.47	GO:0050839	cell adhesion molecule binding
0.41	GO:0005198	structural molecule activity
0.34	GO:0046872	metal ion binding
0.33	GO:0005044	scavenger receptor activity
0.32	GO:0008233	peptidase activity

0.81	GO:0005577	fibrinogen complex
0.50	GO:0031091	platelet alpha granule
0.47	GO:0009897	external side of plasma membrane
0.46	GO:0005938	cell cortex
0.30	GO:0016021	integral component of membrane

0.32

GO:0008233

sp|P14676|PRL_CHICK
Prolactin
Search

PRL

0.92

Prolactin

0.75	GO:0010469	regulation of receptor activity
0.54	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II
0.53	GO:0001937	negative regulation of endothelial cell proliferation
0.53	GO:0046427	positive regulation of JAK-STAT cascade
0.52	GO:0040014	regulation of multicellular organism growth
0.48	GO:0007595	lactation
0.45	GO:0030072	peptide hormone secretion
0.44	GO:0045723	positive regulation of fatty acid biosynthetic process
0.41	GO:0043066	negative regulation of apoptotic process
0.39	GO:1903489	positive regulation of lactation

0.79	GO:0005179	hormone activity
0.46	GO:0005148	prolactin receptor binding
0.36	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.35	GO:0031904	endosome lumen
0.34	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|P14731|LMNB1_CHICK
Lamin-B1
Search

0.69

Lamin

0.36	GO:1904609	cellular response to monosodium L-glutamate
0.36	GO:0090342	regulation of cell aging
0.36	GO:0060047	heart contraction
0.36	GO:0071386	cellular response to corticosterone stimulus
0.36	GO:0031662	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle
0.36	GO:0035722	interleukin-12-mediated signaling pathway
0.35	GO:0046330	positive regulation of JNK cascade
0.34	GO:0006915	apoptotic process
0.34	GO:0022008	neurogenesis
0.34	GO:0046677	response to antibiotic

0.62	GO:0005198	structural molecule activity
0.57	GO:0043274	phospholipase binding
0.35	GO:0008432	JUN kinase binding

0.79	GO:0005882	intermediate filament
0.57	GO:0005652	nuclear lamina
0.54	GO:0031965	nuclear membrane
0.54	GO:0016363	nuclear matrix
0.47	GO:0005654	nucleoplasm
0.45	GO:0019866	organelle inner membrane
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P14732|LMNB2_CHICK
Lamin-B2
Search

0.10	Lamin-L(II)

0.35	GO:1904609	cellular response to monosodium L-glutamate
0.34	GO:0031662	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle
0.34	GO:0071386	cellular response to corticosterone stimulus
0.34	GO:0035722	interleukin-12-mediated signaling pathway
0.34	GO:0046330	positive regulation of JNK cascade
0.34	GO:0015031	protein transport
0.33	GO:0006915	apoptotic process
0.33	GO:0022008	neurogenesis
0.33	GO:0046677	response to antibiotic
0.33	GO:0042493	response to drug

0.62	GO:0005198	structural molecule activity
0.47	GO:0043274	phospholipase binding
0.34	GO:0008432	JUN kinase binding
0.33	GO:0046872	metal ion binding

0.79	GO:0005882	intermediate filament
0.61	GO:0005652	nuclear lamina
0.58	GO:0005635	nuclear envelope
0.47	GO:0031090	organelle membrane
0.45	GO:0016363	nuclear matrix
0.41	GO:0005654	nucleoplasm
0.33	GO:0005739	mitochondrion

sp|P14781|CNTN1_CHICK
Contactin-1
Search

CNTN1

0.92	LOW QUALITY PROTEIN: contactin-1

0.77	GO:0031175	neuron projection development
0.51	GO:0010765	positive regulation of sodium ion transport
0.50	GO:0021549	cerebellum development
0.50	GO:0010976	positive regulation of neuron projection development
0.45	GO:0010628	positive regulation of gene expression
0.39	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.38	GO:0007155	cell adhesion
0.38	GO:0007219	Notch signaling pathway

0.45	GO:0030246	carbohydrate binding
0.37	GO:0005515	protein binding

0.49	GO:0043209	myelin sheath
0.40	GO:0031225	anchored component of membrane
0.39	GO:0045121	membrane raft
0.36	GO:0070062	extracellular exosome
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P14791|HMOX1_CHICK
Heme oxygenase 1
Search

HMOX1

0.57	Heme oxygenase

0.82	GO:0006788	heme oxidation
0.58	GO:0042167	heme catabolic process
0.58	GO:0072719	cellular response to cisplatin
0.58	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron
0.57	GO:0002246	wound healing involved in inflammatory response
0.57	GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.57	GO:0071243	cellular response to arsenic-containing substance
0.56	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.56	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis
0.55	GO:0048662	negative regulation of smooth muscle cell proliferation

0.82	GO:0004392	heme oxygenase (decyclizing) activity
0.50	GO:0042803	protein homodimerization activity
0.46	GO:0020037	heme binding
0.46	GO:0046872	metal ion binding
0.39	GO:0004630	phospholipase D activity
0.37	GO:0019899	enzyme binding
0.35	GO:0004871	signal transducer activity

0.52	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0005783	endoplasmic reticulum
0.44	GO:0005634	nucleus
0.39	GO:0005901	caveola
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.37	GO:0005829	cytosol
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0005615	extracellular space

0.82

EC:1.14.99.3

GO:0004392

sp|P14838|HXB5_CHICK
Homeobox protein Hox-B5 (Fragment)
Search

0.60	Homeobox protein Hox-B5

0.67	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0030855	epithelial cell differentiation
0.53	GO:0006366	transcription by RNA polymerase II
0.52	GO:0010870	positive regulation of receptor biosynthetic process
0.52	GO:0045647	negative regulation of erythrocyte differentiation
0.52	GO:1902680	positive regulation of RNA biosynthetic process
0.52	GO:0060638	mesenchymal-epithelial cell signaling

0.65	GO:0043565	sequence-specific DNA binding
0.59	GO:0003700	DNA binding transcription factor activity
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.50	GO:0035326	enhancer binding
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.44	GO:0005829	cytosol
0.44	GO:0043233	organelle lumen
0.41	GO:0043232	intracellular non-membrane-bounded organelle
0.40	GO:0044446	intracellular organelle part

sp|P14839|HXB6_CHICK
Homeobox protein Hox-B6 (Fragment)
Search

0.62	Homeobox domain containing protein 11

0.67	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:0009653	anatomical structure morphogenesis
0.39	GO:0034101	erythrocyte homeostasis
0.34	GO:0006351	transcription, DNA-templated

0.65	GO:0043565	sequence-specific DNA binding
0.59	GO:0003700	DNA binding transcription factor activity

0.61

GO:0005634

nucleus

sp|P14840|HXB4_CHICK
Homeobox protein Hox-B4
Search

HOXB4

0.84	Homeobox protein Hox-B4

0.67	GO:0007275	multicellular organism development
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:2000738	positive regulation of stem cell differentiation
0.50	GO:0048103	somatic stem cell division
0.49	GO:0048863	stem cell differentiation
0.49	GO:0002011	morphogenesis of an epithelial sheet
0.47	GO:1902680	positive regulation of RNA biosynthetic process
0.47	GO:0008283	cell proliferation

0.63	GO:0043565	sequence-specific DNA binding
0.59	GO:0003700	DNA binding transcription factor activity
0.40	GO:0001012	RNA polymerase II regulatory region DNA binding
0.39	GO:0071837	HMG box domain binding
0.39	GO:0003690	double-stranded DNA binding
0.39	GO:0035326	enhancer binding

0.60	GO:0005634	nucleus
0.46	GO:0005813	centrosome
0.36	GO:0030054	cell junction
0.36	GO:0043233	organelle lumen

sp|P15062|ETS1B_CHICK
Transforming protein p68/c-ets-1
Search

ETS1

0.72	ETS proto-oncogene 1, transcription factor

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0030578	PML body organization
0.55	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell
0.54	GO:0061614	pri-miRNA transcription by RNA polymerase II
0.54	GO:0045648	positive regulation of erythrocyte differentiation
0.53	GO:0010595	positive regulation of endothelial cell migration
0.52	GO:0043535	regulation of blood vessel endothelial cell migration
0.51	GO:0045765	regulation of angiogenesis

0.65	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.49	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0042802	identical protein binding
0.47	GO:0003690	double-stranded DNA binding
0.39	GO:0035035	histone acetyltransferase binding
0.34	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.45	GO:0043233	organelle lumen
0.41	GO:0044446	intracellular organelle part
0.33	GO:0042025	host cell nucleus
0.33	GO:0005737	cytoplasm

sp|P15120|UROK_CHICK
Urokinase-type plasminogen activator
Search

PLAU

0.91	Urokinase-type plasminogen activator

0.72	GO:0031639	plasminogen activation
0.60	GO:0014909	smooth muscle cell migration
0.59	GO:2000097	regulation of smooth muscle cell-matrix adhesion
0.58	GO:0042730	fibrinolysis
0.57	GO:0014910	regulation of smooth muscle cell migration
0.57	GO:0033628	regulation of cell adhesion mediated by integrin
0.55	GO:0001666	response to hypoxia
0.54	GO:0030335	positive regulation of cell migration
0.51	GO:0042127	regulation of cell proliferation
0.51	GO:0010469	regulation of receptor activity

0.69	GO:0004252	serine-type endopeptidase activity
0.50	GO:0016301	kinase activity
0.39	GO:0051219	phosphoprotein binding
0.37	GO:0005102	receptor binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0005044	scavenger receptor activity
0.33	GO:0030247	polysaccharide binding
0.32	GO:0004930	G-protein coupled receptor activity

0.63	GO:0005576	extracellular region
0.52	GO:0009986	cell surface
0.40	GO:0030141	secretory granule
0.39	GO:0045177	apical part of cell
0.38	GO:0031226	intrinsic component of plasma membrane
0.36	GO:0005925	focal adhesion
0.34	GO:0030659	cytoplasmic vesicle membrane
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0031225	anchored component of membrane

0.69

GO:0004252

sp|P15142|HM7X_CHICK
Homeobox protein CHOX-7 (Fragment)
Search

0.78	Gastrulation brain homeobox 1

0.57	GO:0021953	central nervous system neuron differentiation
0.56	GO:0007411	axon guidance
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.54	GO:0021555	midbrain-hindbrain boundary morphogenesis
0.54	GO:0021568	rhombomere 2 development
0.53	GO:0021930	cerebellar granule cell precursor proliferation
0.53	GO:0021549	cerebellum development
0.52	GO:0019230	proprioception

0.63	GO:0043565	sequence-specific DNA binding
0.50	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.49	GO:0001047	core promoter binding
0.49	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003690	double-stranded DNA binding

0.60	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P15143|PO2F1_CHICK
POU domain, class 2, transcription factor 1
Search

POU2F1

0.72	POU domain, class 2, transcription factor 1

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0051254	positive regulation of RNA metabolic process
0.50	GO:0010557	positive regulation of macromolecule biosynthetic process
0.49	GO:0031328	positive regulation of cellular biosynthetic process
0.49	GO:0051253	negative regulation of RNA metabolic process
0.48	GO:0010558	negative regulation of macromolecule biosynthetic process
0.48	GO:0031327	negative regulation of cellular biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0001047	core promoter binding
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003690	double-stranded DNA binding
0.37	GO:0001223	transcription coactivator binding
0.35	GO:0003682	chromatin binding
0.34	GO:0005102	receptor binding

0.61	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.48	GO:0005783	endoplasmic reticulum
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part

sp|P15340|HSP1_CHICK
Sperm histone
Search

0.53	GO:0006397	mRNA processing
0.51	GO:0006323	DNA packaging
0.50	GO:0043484	regulation of RNA splicing
0.49	GO:0007283	spermatogenesis
0.46	GO:0030154	cell differentiation
0.46	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
0.45	GO:0007275	multicellular organism development
0.44	GO:0050684	regulation of mRNA processing
0.43	GO:0006333	chromatin assembly or disassembly
0.43	GO:0034728	nucleosome organization

0.49	GO:0003723	RNA binding
0.42	GO:0003677	DNA binding
0.39	GO:0046872	metal ion binding
0.37	GO:0008168	methyltransferase activity
0.36	GO:0004672	protein kinase activity
0.36	GO:0016874	ligase activity
0.35	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0000786	nucleosome
0.49	GO:0089701	U2AF
0.39	GO:0039615	T=1 icosahedral viral capsid
0.38	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

0.37

EC:2.1.1

GO:0008168

sp|P15505|GCSP_CHICK
Glycine dehydrogenase (decarboxylating), mitochondrial
Search

GLDC

0.71	Glycine dehydrogenase (decarboxylating), mitochondrial

0.75	GO:0006546	glycine catabolic process
0.52	GO:0055114	oxidation-reduction process
0.49	GO:1990830	cellular response to leukemia inhibitory factor
0.41	GO:0036255	response to methylamine
0.41	GO:1903442	response to lipoic acid
0.33	GO:0006091	generation of precursor metabolites and energy

0.78	GO:0016642	oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
0.57	GO:0016829	lyase activity
0.40	GO:0070280	pyridoxal binding
0.39	GO:0016594	glycine binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0047960	glycine dehydrogenase activity
0.36	GO:0019899	enzyme binding
0.36	GO:0030170	pyridoxal phosphate binding
0.33	GO:0009055	electron transfer activity

0.59	GO:0005739	mitochondrion
0.44	GO:0005634	nucleus
0.42	GO:0005886	plasma membrane
0.37	GO:0005960	glycine cleavage complex
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.78

EC:1.4.4

GO:0016642

sp|P15575|B3AT_CHICK
Band 3 anion transport protein
Search

SLC4A1

0.64	Anion exchange protein (Fragment)

0.68	GO:0015698	inorganic anion transport
0.68	GO:0098656	anion transmembrane transport
0.57	GO:0015701	bicarbonate transport
0.47	GO:0051453	regulation of intracellular pH
0.45	GO:0098660	inorganic ion transmembrane transport
0.43	GO:0006814	sodium ion transport
0.40	GO:0098655	cation transmembrane transport
0.35	GO:0010037	response to carbon dioxide
0.35	GO:0010446	response to alkaline pH
0.35	GO:0014823	response to activity

0.82	GO:0005452	inorganic anion exchanger activity
0.57	GO:0015106	bicarbonate transmembrane transporter activity
0.56	GO:0015301	anion:anion antiporter activity
0.56	GO:0030506	ankyrin binding
0.51	GO:0015108	chloride transmembrane transporter activity
0.50	GO:0042803	protein homodimerization activity
0.45	GO:0015296	anion:cation symporter activity
0.44	GO:0015081	sodium ion transmembrane transporter activity
0.35	GO:0043495	protein membrane anchor
0.35	GO:0008022	protein C-terminus binding

0.55	GO:0016323	basolateral plasma membrane
0.53	GO:0030863	cortical cytoskeleton
0.48	GO:0005887	integral component of plasma membrane
0.42	GO:0030018	Z disc
0.37	GO:0072562	blood microparticle
0.36	GO:0070062	extracellular exosome
0.36	GO:0016324	apical plasma membrane
0.35	GO:0014704	intercalated disc
0.34	GO:0009986	cell surface

sp|P15720|MBP_CHICK
Myelin basic protein
Search

MBP

0.96	myelin basic protein isoform X4

0.53	GO:0042552	myelination
0.49	GO:0007605	sensory perception of sound
0.44	GO:0009636	response to toxic substance
0.44	GO:0061024	membrane organization
0.43	GO:0007417	central nervous system development
0.39	GO:1904207	regulation of chemokine (C-C motif) ligand 2 secretion
0.38	GO:0035633	maintenance of permeability of blood-brain barrier
0.38	GO:1904685	positive regulation of metalloendopeptidase activity
0.38	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production
0.38	GO:0034115	negative regulation of heterotypic cell-cell adhesion

0.86	GO:0019911	structural constituent of myelin sheath
0.50	GO:0002020	protease binding
0.49	GO:0005516	calmodulin binding
0.34	GO:0005543	phospholipid binding

0.57	GO:0033269	internode region of axon
0.53	GO:0043209	myelin sheath
0.52	GO:0043025	neuronal cell body
0.41	GO:0043234	protein complex
0.41	GO:0071944	cell periphery
0.33	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P15743|PTHY_CHICK
Parathyroid hormone
Search

PTH

0.97	Parathyroid hormone

0.82	GO:0046326	positive regulation of glucose import
0.80	GO:0006874	cellular calcium ion homeostasis
0.76	GO:0010469	regulation of receptor activity
0.60	GO:0090290	positive regulation of osteoclast proliferation
0.60	GO:0071866	negative regulation of apoptotic process in bone marrow
0.59	GO:0071864	positive regulation of cell proliferation in bone marrow
0.59	GO:0060732	positive regulation of inositol phosphate biosynthetic process
0.59	GO:0045725	positive regulation of glycogen biosynthetic process
0.59	GO:0007202	activation of phospholipase C activity
0.58	GO:0030819	positive regulation of cAMP biosynthetic process

0.79	GO:0005179	hormone activity
0.62	GO:0031856	parathyroid hormone receptor binding
0.58	GO:0051428	peptide hormone receptor binding
0.56	GO:0047485	protein N-terminus binding
0.56	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

0.66	GO:0005576	extracellular region
0.37	GO:0005622	intracellular

sp|P15771|NUCL_CHICK
Nucleolin
Search

NCL

0.87

Nucleolin

0.55	GO:1901838	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I
0.55	GO:0071364	cellular response to epidermal growth factor stimulus
0.53	GO:1990830	cellular response to leukemia inhibitory factor
0.52	GO:0072359	circulatory system development
0.49	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:0009653	anatomical structure morphogenesis
0.49	GO:0017148	negative regulation of translation
0.42	GO:0009303	rRNA transcription
0.41	GO:0007368	determination of left/right symmetry
0.41	GO:0048568	embryonic organ development

0.59	GO:0003723	RNA binding
0.56	GO:0044547	DNA topoisomerase binding
0.53	GO:0042162	telomeric DNA binding
0.52	GO:0008022	protein C-terminus binding
0.48	GO:0042802	identical protein binding
0.36	GO:1990631	ErbB-4 class receptor binding
0.35	GO:0043236	laminin binding
0.34	GO:0042393	histone binding
0.34	GO:0003697	single-stranded DNA binding
0.34	GO:0005509	calcium ion binding

0.50	GO:0036464	cytoplasmic ribonucleoprotein granule
0.50	GO:0005730	nucleolus
0.49	GO:0005938	cell cortex
0.47	GO:0005654	nucleoplasm
0.36	GO:0070062	extracellular exosome
0.34	GO:0009986	cell surface
0.30	GO:0016020	membrane

0.32	EC:3.6	GO:0016817
0.31	KEGG:R07290	GO:0033608

sp|P15979|HA1F_CHICK
Class I histocompatibility antigen, F10 alpha chain
Search

0.58	MHC class I antigen

0.40	GO:0042605	peptide antigen binding
0.35	GO:0042289	MHC class II protein binding
0.32	GO:0046872	metal ion binding

0.38	GO:0009986	cell surface
0.34	GO:0042611	MHC protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P15988|CO6A2_CHICK
Collagen alpha-2(VI) chain
Search

COL6A2

0.83	Collagen type VI alpha 2 chain

0.50	GO:0070208	protein heterotrimerization
0.38	GO:0048747	muscle fiber development
0.38	GO:0007517	muscle organ development
0.38	GO:0007409	axonogenesis
0.36	GO:0009749	response to glucose
0.34	GO:0007155	cell adhesion
0.34	GO:0030574	collagen catabolic process
0.34	GO:0030198	extracellular matrix organization

0.32

GO:0005515

protein binding

0.75	GO:0005581	collagen trimer
0.49	GO:0042383	sarcolemma
0.46	GO:0005578	proteinaceous extracellular matrix
0.45	GO:0005615	extracellular space
0.35	GO:1903561	extracellular vesicle
0.34	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

sp|P15989|CO6A3_CHICK
Collagen alpha-3(VI) chain
Search

COL6A3

0.71	Collagen type VI alpha 3 chain

0.74	GO:0010951	negative regulation of endopeptidase activity
0.44	GO:0048675	axon extension
0.44	GO:0008045	motor neuron axon guidance
0.33	GO:0007155	cell adhesion
0.33	GO:0030574	collagen catabolic process
0.33	GO:0007517	muscle organ development
0.33	GO:0030198	extracellular matrix organization

0.76

GO:0004867

serine-type endopeptidase inhibitor activity

0.75	GO:0005581	collagen trimer
0.52	GO:0042383	sarcolemma
0.49	GO:0005578	proteinaceous extracellular matrix
0.48	GO:0005615	extracellular space
0.34	GO:0098647	collagen beaded filament
0.33	GO:0005788	endoplasmic reticulum lumen
0.33	GO:1903561	extracellular vesicle

sp|P16005|ACHB_CHICK
Acetylcholine receptor subunit beta (Fragment)
Search

0.87	Acetylcholine receptor subunit beta (Fragment)

0.80	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport

0.83	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0004888	transmembrane signaling receptor activity

0.79	GO:0045211	postsynaptic membrane
0.75	GO:0030054	cell junction
0.30	GO:0031224	intrinsic component of membrane

sp|P16039|NPM_CHICK
Nucleophosmin
Search

NPM1

0.96	Nucleophosmin

0.51	GO:0060735	regulation of eIF2 alpha phosphorylation by dsRNA
0.50	GO:0032071	regulation of endodeoxyribonuclease activity
0.49	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation
0.49	GO:0010824	regulation of centrosome duplication
0.49	GO:1904751	positive regulation of protein localization to nucleolus
0.48	GO:0060699	regulation of endoribonuclease activity
0.48	GO:0007569	cell aging
0.48	GO:0007098	centrosome cycle
0.47	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.47	GO:0046607	positive regulation of centrosome cycle

0.50	GO:0051059	NF-kappaB binding
0.50	GO:0003676	nucleic acid binding
0.49	GO:0030957	Tat protein binding
0.47	GO:0043024	ribosomal small subunit binding
0.47	GO:0001105	RNA polymerase II transcription coactivator activity
0.47	GO:0033613	activating transcription factor binding
0.47	GO:0004860	protein kinase inhibitor activity
0.46	GO:0047485	protein N-terminus binding
0.45	GO:0042393	histone binding
0.45	GO:0019901	protein kinase binding

0.48	GO:0001652	granular component
0.48	GO:0031616	spindle pole centrosome
0.45	GO:0016607	nuclear speck
0.43	GO:0032993	protein-DNA complex
0.42	GO:0015934	large ribosomal subunit
0.42	GO:0015935	small ribosomal subunit
0.42	GO:0005829	cytosol
0.39	GO:0043234	protein complex
0.38	GO:0016363	nuclear matrix
0.36	GO:0005925	focal adhesion

sp|P16047|TGFB3_CHICK
Transforming growth factor beta-3
Search

TGFB3

0.97	Transforming growth factor beta-3

0.81	GO:0016049	cell growth
0.75	GO:0010469	regulation of receptor activity
0.68	GO:0043932	ossification involved in bone remodeling
0.67	GO:0010936	negative regulation of macrophage cytokine production
0.66	GO:0032967	positive regulation of collagen biosynthetic process
0.66	GO:0032570	response to progesterone
0.65	GO:0060325	face morphogenesis
0.65	GO:0070483	detection of hypoxia
0.65	GO:0030501	positive regulation of bone mineralization
0.65	GO:0010718	positive regulation of epithelial to mesenchymal transition

0.85	GO:0005160	transforming growth factor beta receptor binding
0.78	GO:0008083	growth factor activity
0.66	GO:0050431	transforming growth factor beta binding
0.57	GO:0042802	identical protein binding
0.47	GO:0005125	cytokine activity
0.38	GO:0046982	protein heterodimerization activity
0.33	GO:0003823	antigen binding
0.33	GO:0043539	protein serine/threonine kinase activator activity
0.33	GO:0019899	enzyme binding

0.73	GO:0005615	extracellular space
0.56	GO:0031012	extracellular matrix
0.43	GO:0043231	intracellular membrane-bounded organelle
0.40	GO:0030315	T-tubule
0.39	GO:0043025	neuronal cell body
0.39	GO:0030141	secretory granule
0.38	GO:0009986	cell surface
0.35	GO:0060205	cytoplasmic vesicle lumen
0.33	GO:0005902	microvillus
0.30	GO:0016021	integral component of membrane

sp|P16053|NFM_CHICK
Neurofilament medium polypeptide
Search

NEFM

0.95	neurofilament medium polypeptide

0.77	GO:0061564	axon development
0.49	GO:0060052	neurofilament cytoskeleton organization
0.46	GO:1990830	cellular response to leukemia inhibitory factor
0.39	GO:0045110	intermediate filament bundle assembly
0.37	GO:0031133	regulation of axon diameter
0.37	GO:0008088	axo-dendritic transport
0.36	GO:0021762	substantia nigra development
0.35	GO:0000226	microtubule cytoskeleton organization
0.35	GO:0031099	regeneration
0.34	GO:0009611	response to wounding

0.62	GO:0005198	structural molecule activity
0.35	GO:0005515	protein binding
0.33	GO:0015643	toxic substance binding

0.85	GO:0005883	neurofilament
0.56	GO:0097418	neurofibrillary tangle
0.46	GO:0043209	myelin sheath
0.45	GO:0036464	cytoplasmic ribonucleoprotein granule
0.44	GO:0031965	nuclear membrane
0.42	GO:0005654	nucleoplasm
0.37	GO:0030424	axon
0.36	GO:0031594	neuromuscular junction
0.36	GO:0014069	postsynaptic density
0.34	GO:0005615	extracellular space

sp|P16075|MYOD1_CHICK
Myoblast determination protein 1 homolog
Search

MYOD1

0.90	Myogenic factor

0.80	GO:0007517	muscle organ development
0.57	GO:0043503	skeletal muscle fiber adaptation
0.57	GO:0007518	myoblast fate determination
0.56	GO:0014908	myotube differentiation involved in skeletal muscle regeneration
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:2000818	negative regulation of myoblast proliferation
0.56	GO:1901741	positive regulation of myoblast fusion
0.56	GO:0014904	myotube cell development
0.56	GO:0043415	positive regulation of skeletal muscle tissue regeneration

0.67	GO:0046983	protein dimerization activity
0.54	GO:0003677	DNA binding
0.53	GO:0035257	nuclear hormone receptor binding
0.52	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.50	GO:0003713	transcription coactivator activity
0.50	GO:0001067	regulatory region nucleic acid binding
0.49	GO:0003682	chromatin binding
0.42	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.35	GO:0005249	voltage-gated potassium channel activity

0.60	GO:0005634	nucleus
0.51	GO:0030016	myofibril
0.48	GO:0005667	transcription factor complex
0.47	GO:0000785	chromatin
0.46	GO:0005829	cytosol
0.46	GO:0070013	intracellular organelle lumen
0.35	GO:0008076	voltage-gated potassium channel complex

sp|P16236|REL_CHICK
Proto-oncogene c-Rel
Search

REL

0.97	V-rel avian reticuloendotheliosis viral oncogene homolog

0.82	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.71	GO:0045893	positive regulation of transcription, DNA-templated
0.55	GO:0032688	negative regulation of interferon-beta production
0.52	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.50	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.50	GO:0006357	regulation of transcription by RNA polymerase II
0.49	GO:0006366	transcription by RNA polymerase II
0.48	GO:0038061	NIK/NF-kappaB signaling
0.47	GO:0010629	negative regulation of gene expression
0.45	GO:0006954	inflammatory response

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.51	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0003682	chromatin binding
0.40	GO:0046982	protein heterodimerization activity
0.36	GO:0042803	protein homodimerization activity
0.35	GO:0004652	polynucleotide adenylyltransferase activity
0.34	GO:0071532	ankyrin repeat binding
0.34	GO:0051059	NF-kappaB binding
0.34	GO:0070491	repressing transcription factor binding

0.61	GO:0005634	nucleus
0.52	GO:0071159	NF-kappaB complex
0.49	GO:0033256	I-kappaB/NF-kappaB complex
0.49	GO:0005737	cytoplasm
0.36	GO:0005667	transcription factor complex
0.34	GO:0070013	intracellular organelle lumen
0.34	GO:0030430	host cell cytoplasm
0.34	GO:0042025	host cell nucleus
0.33	GO:0000785	chromatin

0.35

EC:2.7.7.19

GO:0004652

sp|P16419|MYPC2_CHICK
Myosin-binding protein C, fast-type
Search

0.97	Myosin binding protein C, fast type a

0.77	GO:0006936	muscle contraction
0.72	GO:0071688	striated muscle myosin thick filament assembly
0.69	GO:0045214	sarcomere organization
0.61	GO:0007015	actin filament organization
0.55	GO:0060537	muscle tissue development
0.48	GO:0003210	cardiac atrium formation
0.47	GO:0003211	cardiac ventricle formation
0.46	GO:0060415	muscle tissue morphogenesis
0.45	GO:0002027	regulation of heart rate
0.44	GO:0007155	cell adhesion

0.72	GO:0097493	structural molecule activity conferring elasticity
0.72	GO:0051371	muscle alpha-actinin binding
0.70	GO:0008307	structural constituent of muscle
0.63	GO:0051015	actin filament binding
0.39	GO:0005200	structural constituent of cytoskeleton

0.71	GO:0005859	muscle myosin complex
0.70	GO:0031430	M band
0.68	GO:0030018	Z disc
0.50	GO:0032982	myosin filament
0.37	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P16476|PEPE_CHICK
Embryonic pepsinogen
Search

0.91	Embryonic pepsinogen

0.61	GO:0006508	proteolysis
0.49	GO:0051604	protein maturation
0.49	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.46	GO:0007586	digestion
0.45	GO:0030163	protein catabolic process
0.45	GO:0006914	autophagy
0.34	GO:0044267	cellular protein metabolic process

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.43	GO:0042803	protein homodimerization activity

0.46	GO:0005768	endosome
0.41	GO:0005576	extracellular region
0.36	GO:0044433	cytoplasmic vesicle part
0.35	GO:0031974	membrane-enclosed lumen
0.33	GO:0005764	lysosome

sp|P16527|MARCS_CHICK
Myristoylated alanine-rich C-kinase substrate
Search

MARCKS

0.97	Myristoylated alanine-rich protein kinase C substrate a

0.53	GO:0010842	retina layer formation
0.52	GO:0035914	skeletal muscle cell differentiation
0.50	GO:0060541	respiratory system development
0.50	GO:0007420	brain development
0.47	GO:0051764	actin crosslink formation
0.45	GO:0051017	actin filament bundle assembly
0.44	GO:0003381	epithelial cell morphogenesis involved in gastrulation
0.44	GO:0051260	protein homooligomerization
0.43	GO:0060027	convergent extension involved in gastrulation
0.43	GO:0016310	phosphorylation

0.77	GO:0005516	calmodulin binding
0.46	GO:0005080	protein kinase C binding
0.45	GO:0003779	actin binding
0.44	GO:0016301	kinase activity
0.43	GO:0032403	protein complex binding
0.43	GO:0042802	identical protein binding
0.35	GO:0001786	phosphatidylserine binding
0.34	GO:0008995	ribonuclease E activity
0.33	GO:0004521	endoribonuclease activity
0.33	GO:0046872	metal ion binding

0.48	GO:0042585	germinal vesicle
0.46	GO:0032432	actin filament bundle
0.44	GO:0005813	centrosome
0.43	GO:0005938	cell cortex
0.37	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0044307	dendritic branch
0.35	GO:0005925	focal adhesion
0.35	GO:0032059	bleb
0.35	GO:0001520	outer dense fiber

0.32

EC:6.5.1.1

GO:0003910

sp|P16580|GLNA_CHICK
Glutamine synthetase
Search

GLUL

0.46	Glutamine synthetase

0.76	GO:0006542	glutamine biosynthetic process
0.48	GO:0008283	cell proliferation
0.48	GO:0009749	response to glucose
0.46	GO:0031667	response to nutrient levels
0.44	GO:0031668	cellular response to extracellular stimulus
0.41	GO:0033554	cellular response to stress
0.39	GO:0051968	positive regulation of synaptic transmission, glutamatergic
0.39	GO:0019676	ammonia assimilation cycle
0.38	GO:0032024	positive regulation of insulin secretion
0.38	GO:0050679	positive regulation of epithelial cell proliferation

0.76	GO:0004356	glutamate-ammonia ligase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0042802	identical protein binding
0.42	GO:0004351	glutamate decarboxylase activity
0.39	GO:0016595	glutamate binding
0.39	GO:0045503	dynein light chain binding
0.37	GO:0030145	manganese ion binding
0.35	GO:0000287	magnesium ion binding

0.50	GO:0097386	glial cell projection
0.47	GO:0043209	myelin sheath
0.47	GO:0044297	cell body
0.44	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.38	GO:0043679	axon terminus
0.38	GO:0005791	rough endoplasmic reticulum
0.37	GO:0036477	somatodendritic compartment
0.36	GO:0070062	extracellular exosome
0.35	GO:0043234	protein complex

0.76	EC:6.3.1.2	GO:0004356
0.76	KEGG:R00253	GO:0004356

sp|P16924|P4HA1_CHICK
Prolyl 4-hydroxylase subunit alpha-1
Search

P4HA1

0.82	Prolyl 4-hydroxylase, alpha polypeptide I

0.84	GO:0019511	peptidyl-proline hydroxylation
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0019471	4-hydroxyproline metabolic process
0.47	GO:0030199	collagen fibril organization
0.34	GO:0050482	arachidonic acid secretion
0.33	GO:0016042	lipid catabolic process
0.33	GO:0006644	phospholipid metabolic process

0.85	GO:0004656	procollagen-proline 4-dioxygenase activity
0.79	GO:0031418	L-ascorbic acid binding
0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.62	GO:0005506	iron ion binding
0.48	GO:0042802	identical protein binding
0.34	GO:0004623	phospholipase A2 activity
0.33	GO:0005509	calcium ion binding

0.70	GO:0005783	endoplasmic reticulum
0.43	GO:0005739	mitochondrion
0.42	GO:1990204	oxidoreductase complex
0.39	GO:0044446	intracellular organelle part
0.37	GO:0043233	organelle lumen
0.35	GO:0005581	collagen trimer
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.85	EC:1.14.11.2	GO:0004656
0.85	KEGG:R03219	GO:0004656

sp|P17153|ANXA5_CHICK
Annexin A5
Search

ANXA5

0.57

Annexin

0.85	GO:0050819	negative regulation of coagulation
0.48	GO:0010033	response to organic substance
0.41	GO:0032879	regulation of localization
0.40	GO:0040012	regulation of locomotion
0.40	GO:0007596	blood coagulation
0.38	GO:0032717	negative regulation of interleukin-8 production
0.37	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.37	GO:0048523	negative regulation of cellular process
0.37	GO:0007219	Notch signaling pathway
0.37	GO:0030855	epithelial cell differentiation

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.38	GO:0048306	calcium-dependent protein binding
0.38	GO:0051059	NF-kappaB binding
0.36	GO:0042802	identical protein binding
0.36	GO:0015085	calcium ion transmembrane transporter activity
0.35	GO:0035374	chondroitin sulfate binding
0.35	GO:0004859	phospholipase inhibitor activity
0.35	GO:0017046	peptide hormone binding
0.35	GO:0030971	receptor tyrosine kinase binding

0.57	GO:0072563	endothelial microparticle
0.52	GO:0009897	external side of plasma membrane
0.39	GO:0031982	vesicle
0.38	GO:0043230	extracellular organelle
0.38	GO:0005622	intracellular
0.36	GO:0012505	endomembrane system
0.36	GO:0005925	focal adhesion
0.35	GO:0034704	calcium channel complex
0.35	GO:0014704	intercalated disc
0.35	GO:0044422	organelle part

sp|P17200|ACM4_CHICK
Muscarinic acetylcholine receptor M4
Search

CHRM4

0.81	Muscarinic acetylcholine receptor

0.85	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.70	GO:0040012	regulation of locomotion
0.58	GO:0008016	regulation of heart contraction
0.57	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.48	GO:0007271	synaptic transmission, cholinergic
0.48	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.46	GO:0009615	response to virus
0.42	GO:0006940	regulation of smooth muscle contraction
0.37	GO:1903523	negative regulation of blood circulation
0.35	GO:0007194	negative regulation of adenylate cyclase activity

0.85	GO:0016907	G-protein coupled acetylcholine receptor activity
0.51	GO:1990763	arrestin family protein binding
0.34	GO:0005085	guanyl-nucleotide exchange factor activity
0.33	GO:0008144	drug binding

0.79	GO:0045211	postsynaptic membrane
0.75	GO:0030054	cell junction
0.67	GO:0005887	integral component of plasma membrane
0.39	GO:0032280	symmetric synapse
0.39	GO:0043679	axon terminus
0.38	GO:0032279	asymmetric synapse
0.38	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.34	GO:0042383	sarcolemma
0.34	GO:0099572	postsynaptic specialization

sp|P17251|PTHR_CHICK
Parathyroid hormone-related protein
Search

PTHLH

0.97	Parathyroid hormone like hormone

0.85	GO:0032330	regulation of chondrocyte differentiation
0.75	GO:0010469	regulation of receptor activity
0.59	GO:0061037	negative regulation of cartilage development
0.59	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.58	GO:0030819	positive regulation of cAMP biosynthetic process
0.55	GO:0045596	negative regulation of cell differentiation
0.54	GO:0001501	skeletal system development
0.51	GO:0002076	osteoblast development
0.43	GO:0060255	regulation of macromolecule metabolic process
0.40	GO:0042127	regulation of cell proliferation

0.79	GO:0005179	hormone activity
0.62	GO:0051428	peptide hormone receptor binding

0.66	GO:0005576	extracellular region
0.51	GO:0005794	Golgi apparatus
0.50	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol

sp|P17277|HXA4_CHICK
Homeobox protein Hox-A4
Search

HOXA4

0.89	Homeobox protein Hox-delta4

0.65	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:0048863	stem cell differentiation
0.46	GO:0006366	transcription by RNA polymerase II
0.46	GO:0009653	anatomical structure morphogenesis
0.45	GO:1902680	positive regulation of RNA biosynthetic process
0.38	GO:0061448	connective tissue development

0.64	GO:0043565	sequence-specific DNA binding
0.58	GO:0003700	DNA binding transcription factor activity
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003690	double-stranded DNA binding
0.39	GO:0071837	HMG box domain binding
0.39	GO:0035326	enhancer binding

0.61	GO:0005634	nucleus
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0030054	cell junction
0.44	GO:0044446	intracellular organelle part

sp|P17278|HXD4_CHICK
Homeobox protein Hox-D4
Search

HOXD4

0.97	Homeobox protein Hox-D4

0.67	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0048863	stem cell differentiation
0.50	GO:0006366	transcription by RNA polymerase II
0.49	GO:1902680	positive regulation of RNA biosynthetic process
0.49	GO:0009653	anatomical structure morphogenesis
0.34	GO:0002376	immune system process

0.64	GO:0043565	sequence-specific DNA binding
0.59	GO:0003700	DNA binding transcription factor activity
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.50	GO:0030054	cell junction
0.47	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part

sp|P17678|GATA1_CHICK
Erythroid transcription factor
Search

0.69	Erythroid transcription factor

0.65	GO:0030222	eosinophil differentiation
0.62	GO:0030221	basophil differentiation
0.60	GO:0030219	megakaryocyte differentiation
0.59	GO:0048821	erythrocyte development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0010725	regulation of primitive erythrocyte differentiation
0.55	GO:0045648	positive regulation of erythrocyte differentiation
0.54	GO:0010724	regulation of definitive erythrocyte differentiation

0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0070742	C2H2 zinc finger domain binding
0.55	GO:0001085	RNA polymerase II transcription factor binding
0.54	GO:0044212	transcription regulatory region DNA binding
0.53	GO:0003682	chromatin binding
0.52	GO:0003690	double-stranded DNA binding
0.50	GO:0008301	DNA binding, bending
0.49	GO:0002039	p53 binding

0.53	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.49	GO:0017053	transcriptional repressor complex
0.45	GO:0032993	protein-DNA complex
0.39	GO:0070013	intracellular organelle lumen
0.37	GO:0044446	intracellular organelle part

0.34

GO:0032041

sp|P17785|ANXA2_CHICK
Annexin A2
Search

ANXA2

0.59

Annexin

0.72	GO:0043086	negative regulation of catalytic activity
0.59	GO:0052362	catabolism by host of symbiont protein
0.59	GO:0044147	negative regulation of development of symbiont involved in interaction with host
0.59	GO:1905597	positive regulation of low-density lipoprotein particle receptor binding
0.59	GO:1905599	positive regulation of low-density lipoprotein receptor activity
0.59	GO:1905581	positive regulation of low-density lipoprotein particle clearance
0.58	GO:1905602	positive regulation of receptor-mediated endocytosis involved in cholesterol transport
0.58	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process
0.57	GO:0036035	osteoclast development
0.57	GO:0052405	negative regulation by host of symbiont molecular function

0.85	GO:0004859	phospholipase inhibitor activity
0.81	GO:0005544	calcium-dependent phospholipid binding
0.71	GO:0008092	cytoskeletal protein binding
0.69	GO:0005509	calcium ion binding
0.56	GO:0098641	cadherin binding involved in cell-cell adhesion
0.56	GO:0044548	S100 protein binding
0.55	GO:0048306	calcium-dependent protein binding
0.54	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.54	GO:0002020	protease binding
0.49	GO:0042802	identical protein binding

0.58	GO:1990667	PCSK9-AnxA2 complex
0.53	GO:0035749	myelin sheath adaxonal region
0.53	GO:0005913	cell-cell adherens junction
0.53	GO:0031902	late endosome membrane
0.53	GO:0030496	midbody
0.53	GO:0043220	Schmidt-Lanterman incisure
0.53	GO:0005811	lipid droplet
0.53	GO:0070062	extracellular exosome
0.53	GO:0005765	lysosomal membrane
0.52	GO:0098857	membrane microdomain

sp|P17790|BASI_CHICK
Basigin
Search

BSG

0.92	Leukocyte activation antigen M6

0.39	GO:0072659	protein localization to plasma membrane
0.39	GO:0046697	decidualization
0.39	GO:0007566	embryo implantation
0.38	GO:0051591	response to cAMP
0.38	GO:0042475	odontogenesis of dentin-containing tooth
0.38	GO:0043434	response to peptide hormone
0.38	GO:0046689	response to mercury ion
0.37	GO:0002027	regulation of heart rate
0.36	GO:0071804	cellular potassium ion transport
0.36	GO:0006814	sodium ion transport

0.50	GO:0045296	cadherin binding
0.40	GO:0005537	mannose binding
0.37	GO:0030552	cAMP binding
0.37	GO:0005216	ion channel activity
0.36	GO:0022832	voltage-gated channel activity
0.36	GO:0015079	potassium ion transmembrane transporter activity
0.35	GO:0004252	serine-type endopeptidase activity
0.34	GO:0008028	monocarboxylic acid transmembrane transporter activity

0.52	GO:0002080	acrosomal membrane
0.42	GO:0042470	melanosome
0.40	GO:0005886	plasma membrane
0.40	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0045121	membrane raft
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0004252

sp|P17920|MYOG_CHICK
Myogenin
Search

MYOG

0.97	Myogenic factor MyoG

0.81	GO:0007517	muscle organ development
0.61	GO:0048743	positive regulation of skeletal muscle fiber development
0.60	GO:0014706	striated muscle tissue development
0.60	GO:1901739	regulation of myoblast fusion
0.60	GO:0014737	positive regulation of muscle atrophy
0.59	GO:0045663	positive regulation of myoblast differentiation
0.58	GO:0014894	response to denervation involved in regulation of muscle adaptation
0.58	GO:0014891	striated muscle atrophy
0.57	GO:0014842	regulation of skeletal muscle satellite cell proliferation
0.57	GO:0071285	cellular response to lithium ion

0.68	GO:0046983	protein dimerization activity
0.58	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.56	GO:0070888	E-box binding
0.54	GO:0031490	chromatin DNA binding
0.54	GO:0001047	core promoter binding
0.52	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.49	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.32	GO:0004725	protein tyrosine phosphatase activity

0.61	GO:0005634	nucleus
0.47	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.38	GO:0032993	protein-DNA complex
0.36	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

0.32

EC:3.1.3.48

GO:0004725

sp|P17923|NFIA_CHICK
Nuclear factor 1 A-type
Search

NFIA

0.77	Nuclear factor 1 A-type

0.66	GO:0006260	DNA replication
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0006351	transcription, DNA-templated
0.55	GO:0060074	synapse maturation
0.54	GO:0072189	ureter development
0.49	GO:1902680	positive regulation of RNA biosynthetic process
0.43	GO:1902679	negative regulation of RNA biosynthetic process
0.34	GO:0014070	response to organic cyclic compound

0.61	GO:0003700	DNA binding transcription factor activity
0.52	GO:0003677	DNA binding
0.49	GO:0003682	chromatin binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.47	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.48	GO:0030054	cell junction
0.45	GO:0043233	organelle lumen
0.41	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P17924|NFIB_CHICK
Nuclear factor 1 B-type
Search

NFIB

0.79	Nuclear factor 1 B-type

0.66	GO:0006260	DNA replication
0.63	GO:0061141	lung ciliated cell differentiation
0.63	GO:2000795	negative regulation of epithelial cell proliferation involved in lung morphogenesis
0.62	GO:0021740	principal sensory nucleus of trigeminal nerve development
0.62	GO:2000790	regulation of mesenchymal cell proliferation involved in lung development
0.62	GO:0060486	Clara cell differentiation
0.61	GO:0060509	Type I pneumocyte differentiation
0.61	GO:0060510	Type II pneumocyte differentiation
0.61	GO:0021960	anterior commissure morphogenesis
0.61	GO:0072201	negative regulation of mesenchymal cell proliferation

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0001106	RNA polymerase II transcription corepressor activity

0.61	GO:0044300	cerebellar mossy fiber
0.61	GO:0005634	nucleus
0.49	GO:0031974	membrane-enclosed lumen
0.45	GO:0043232	intracellular non-membrane-bounded organelle
0.44	GO:0044446	intracellular organelle part

sp|P17926|NFIC_CHICK
Nuclear factor 1 C-type
Search

NFIC

0.78	Nuclear factor 1 C-type

0.65	GO:0006260	DNA replication
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:0042475	odontogenesis of dentin-containing tooth
0.47	GO:1902680	positive regulation of RNA biosynthetic process
0.46	GO:1902679	negative regulation of RNA biosynthetic process
0.34	GO:0007608	sensory perception of smell

0.60	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.33	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.42	GO:0043233	organelle lumen
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P18080|HEM0_CHICK
5-aminolevulinate synthase, erythroid-specific, mitochondrial
Search

0.63	5-aminolevulinate synthase, erythroid-specific, mitochondrial

0.72	GO:0006782	protoporphyrinogen IX biosynthetic process
0.45	GO:0042541	hemoglobin biosynthetic process
0.43	GO:0030218	erythrocyte differentiation
0.41	GO:0035162	embryonic hemopoiesis
0.41	GO:0061515	myeloid cell development
0.41	GO:0001666	response to hypoxia
0.36	GO:0006879	cellular iron ion homeostasis
0.35	GO:0070541	response to platinum ion
0.35	GO:0032025	response to cobalt ion
0.35	GO:0034698	response to gonadotropin

0.84	GO:0003870	5-aminolevulinate synthase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.46	GO:0042802	identical protein binding
0.34	GO:0016874	ligase activity

0.74	GO:0005759	mitochondrial matrix
0.45	GO:0005829	cytosol
0.45	GO:0005654	nucleoplasm
0.37	GO:0031966	mitochondrial membrane
0.37	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.84	EC:2.3.1.37	GO:0003870
0.84	KEGG:R00830	GO:0003870

sp|P18254|IGF1_CHICK
Insulin-like growth factor I
Search

IGF1

0.89	IGF-I splicing variant class 1

0.76	GO:0010469	regulation of receptor activity
0.58	GO:0051050	positive regulation of transport
0.57	GO:0045725	positive regulation of glycogen biosynthetic process
0.57	GO:0048009	insulin-like growth factor receptor signaling pathway
0.55	GO:0046324	regulation of glucose import
0.54	GO:1904073	regulation of trophectodermal cell proliferation
0.54	GO:1905460	negative regulation of vascular associated smooth muscle cell apoptotic process
0.54	GO:2001234	negative regulation of apoptotic signaling pathway
0.54	GO:0050708	regulation of protein secretion
0.53	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development

0.79	GO:0005179	hormone activity
0.78	GO:0008083	growth factor activity
0.59	GO:0005159	insulin-like growth factor receptor binding
0.51	GO:0005158	insulin receptor binding
0.50	GO:0005178	integrin binding

0.73	GO:0005615	extracellular space
0.58	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex
0.53	GO:0036454	growth factor complex
0.43	GO:0070382	exocytic vesicle
0.39	GO:0005829	cytosol
0.35	GO:0031093	platelet alpha granule lumen
0.30	GO:0016021	integral component of membrane

sp|P18302|DREB_CHICK
Drebrin
Search

DBN1

0.97

Drebrin E

0.74	GO:0007015	actin filament organization
0.63	GO:0010643	cell communication by chemical coupling
0.61	GO:0010644	cell communication by electrical coupling
0.58	GO:0061351	neural precursor cell proliferation
0.56	GO:0032507	maintenance of protein location in cell
0.54	GO:0007399	nervous system development
0.53	GO:0030154	cell differentiation
0.38	GO:0050773	regulation of dendrite development
0.37	GO:0050804	modulation of chemical synaptic transmission
0.37	GO:1904113	negative regulation of muscle filament sliding

0.74	GO:0003779	actin binding
0.56	GO:0045296	cadherin binding
0.41	GO:0005522	profilin binding
0.36	GO:0032403	protein complex binding
0.34	GO:0046872	metal ion binding
0.33	GO:0019904	protein domain specific binding
0.33	GO:0008017	microtubule binding

0.59	GO:0030426	growth cone
0.56	GO:0005921	gap junction
0.53	GO:0015629	actin cytoskeleton
0.43	GO:0071944	cell periphery
0.40	GO:0099568	cytoplasmic region
0.37	GO:0030425	dendrite
0.36	GO:0044430	cytoskeletal part
0.36	GO:0044308	axonal spine
0.36	GO:0030027	lamellipodium
0.36	GO:0060076	excitatory synapse

sp|P18359|DEST_CHICK
Destrin
Search

DSTN

0.94	Destrin, actin depolymerizing factor

0.84	GO:0030042	actin filament depolymerization
0.78	GO:0030836	positive regulation of actin filament depolymerization
0.72	GO:0051014	actin filament severing
0.47	GO:0046716	muscle cell cellular homeostasis
0.47	GO:0045214	sarcomere organization
0.46	GO:0007519	skeletal muscle tissue development
0.41	GO:0001842	neural fold formation
0.40	GO:0001755	neural crest cell migration
0.40	GO:0044794	positive regulation by host of viral process
0.40	GO:0061001	regulation of dendritic spine morphogenesis

0.74	GO:0003779	actin binding
0.55	GO:0032403	protein complex binding
0.38	GO:0005102	receptor binding
0.35	GO:0019903	protein phosphatase binding
0.35	GO:1902936	phosphatidylinositol bisphosphate binding

0.74	GO:0015629	actin cytoskeleton
0.52	GO:0030863	cortical cytoskeleton
0.47	GO:0044430	cytoskeletal part
0.46	GO:0030018	Z disc
0.42	GO:0016363	nuclear matrix
0.41	GO:0030027	lamellipodium
0.40	GO:0032587	ruffle membrane
0.40	GO:0005615	extracellular space
0.39	GO:0005911	cell-cell junction
0.38	GO:1903561	extracellular vesicle

sp|P18444|MYCN_CHICK
N-myc proto-oncogene protein
Search

0.88	Transcriptional regulator Myc-A

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0045607	regulation of inner ear auditory receptor cell differentiation
0.50	GO:0048712	negative regulation of astrocyte differentiation
0.49	GO:0001502	cartilage condensation
0.49	GO:0002053	positive regulation of mesenchymal cell proliferation
0.49	GO:2000378	negative regulation of reactive oxygen species metabolic process
0.48	GO:0042733	embryonic digit morphogenesis
0.48	GO:0048704	embryonic skeletal system morphogenesis

0.67	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.46	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0019900	kinase binding
0.34	GO:0003743	translation initiation factor activity
0.33	GO:0017025	TBP-class protein binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0016779	nucleotidyltransferase activity

0.61	GO:0005634	nucleus
0.43	GO:0031974	membrane-enclosed lumen
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0044446	intracellular organelle part
0.36	GO:0048471	perinuclear region of cytoplasm

0.32	EC:2.7.7	GO:0016779
0.32	KEGG:R03876	GO:0004842

sp|P18460|FGFR3_CHICK
Fibroblast growth factor receptor 3
Search

FGFR3

0.62	Fibroblast growth factor receptor

0.82	GO:0008543	fibroblast growth factor receptor signaling pathway
0.78	GO:0008284	positive regulation of cell proliferation
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.56	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
0.55	GO:0010518	positive regulation of phospholipase activity
0.55	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.54	GO:0097191	extrinsic apoptotic signaling pathway
0.53	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.52	GO:0046777	protein autophosphorylation
0.42	GO:0070977	bone maturation

0.85	GO:0005007	fibroblast growth factor-activated receptor activity
0.55	GO:0017134	fibroblast growth factor binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0042802	identical protein binding
0.41	GO:0004908	interleukin-1 receptor activity
0.37	GO:0008083	growth factor activity
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity

0.51	GO:0030133	transport vesicle
0.48	GO:0005794	Golgi apparatus
0.47	GO:0005783	endoplasmic reticulum
0.46	GO:0005887	integral component of plasma membrane
0.40	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005764	lysosome
0.39	GO:0009898	cytoplasmic side of plasma membrane
0.39	GO:0009986	cell surface
0.36	GO:0005634	nucleus
0.35	GO:0005925	focal adhesion

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|P18461|FGFR2_CHICK
Fibroblast growth factor receptor 2
Search

FGFR2

0.76	Fibroblast growth factor receptor

0.80	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0008284	positive regulation of cell proliferation
0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.54	GO:0010518	positive regulation of phospholipase activity
0.53	GO:0048701	embryonic cranial skeleton morphogenesis
0.52	GO:0046777	protein autophosphorylation
0.52	GO:0043410	positive regulation of MAPK cascade
0.44	GO:0060615	mammary gland bud formation
0.44	GO:0060667	branch elongation involved in salivary gland morphogenesis
0.44	GO:0060915	mesenchymal cell differentiation involved in lung development

0.84	GO:0005007	fibroblast growth factor-activated receptor activity
0.55	GO:0017134	fibroblast growth factor binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0042803	protein homodimerization activity
0.35	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:1901681	sulfur compound binding
0.35	GO:0016303	1-phosphatidylinositol-3-kinase activity

0.49	GO:0005938	cell cortex
0.49	GO:0009986	cell surface
0.49	GO:0031012	extracellular matrix
0.47	GO:0005654	nucleoplasm
0.46	GO:0005887	integral component of plasma membrane
0.42	GO:0060076	excitatory synapse
0.36	GO:0031410	cytoplasmic vesicle
0.36	GO:0005794	Golgi apparatus

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

sp|P18519|TNR16_CHICK
Tumor necrosis factor receptor superfamily member 16
Search

NGFR

0.96	Nerve growth factor receptor b

0.74	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.72	GO:1904646	cellular response to amyloid-beta
0.72	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II
0.71	GO:0051402	neuron apoptotic process
0.70	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.69	GO:0007266	Rho protein signal transduction
0.68	GO:1900182	positive regulation of protein localization to nucleus
0.54	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.53	GO:0010977	negative regulation of neuron projection development
0.52	GO:0032496	response to lipopolysaccharide

0.73	GO:0005035	death receptor activity
0.70	GO:0015026	coreceptor activity
0.65	GO:0031625	ubiquitin protein ligase binding
0.65	GO:0005516	calmodulin binding
0.56	GO:0048406	nerve growth factor binding

0.50	GO:0043005	neuron projection
0.49	GO:0005886	plasma membrane
0.43	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P18625|FOSL2_CHICK
Fos-related antigen 2
Search

FOSL2

0.97	FOS like 2, AP-1 transcription factor subunit

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0003334	keratinocyte development
0.57	GO:0048146	positive regulation of fibroblast proliferation
0.54	GO:0006366	transcription by RNA polymerase II
0.53	GO:0045893	positive regulation of transcription, DNA-templated
0.45	GO:2000690	regulation of cardiac muscle cell myoblast differentiation
0.44	GO:0035994	response to muscle stretch
0.44	GO:0045672	positive regulation of osteoclast differentiation
0.43	GO:0071277	cellular response to calcium ion
0.43	GO:0035914	skeletal muscle cell differentiation

0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.55	GO:0003682	chromatin binding
0.43	GO:0070412	R-SMAD binding
0.43	GO:0001102	RNA polymerase II activating transcription factor binding
0.43	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.42	GO:0001046	core promoter sequence-specific DNA binding
0.42	GO:0000987	proximal promoter sequence-specific DNA binding
0.40	GO:0046982	protein heterodimerization activity

0.51	GO:0005654	nucleoplasm
0.44	GO:0035976	transcription factor AP-1 complex
0.40	GO:0032993	protein-DNA complex
0.35	GO:0070552	BRISC complex
0.35	GO:0070531	BRCA1-A complex
0.34	GO:0043005	neuron projection
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0005829	cytosol
0.33	GO:0042025	host cell nucleus
0.30	GO:0016020	membrane

sp|P18652|KS6AA_CHICK
Ribosomal protein S6 kinase 2 alpha
Search

RPS6KA1

0.74	Ribosomal protein S6 kinase 2 alpha

0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.56	GO:2000491	positive regulation of hepatic stellate cell activation
0.52	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.49	GO:0006915	apoptotic process
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II
0.38	GO:0072574	hepatocyte proliferation
0.34	GO:0043555	regulation of translation in response to stress
0.34	GO:0030307	positive regulation of cell growth
0.34	GO:0043620	regulation of DNA-templated transcription in response to stress

0.70	GO:0004674	protein serine/threonine kinase activity
0.64	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.51	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.35	GO:0008134	transcription factor binding
0.35	GO:0031492	nucleosomal DNA binding

0.46	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0044446	intracellular organelle part
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0043233	organelle lumen

0.70

GO:0004674

sp|P18660|RLA1_CHICK
60S acidic ribosomal protein P1
Search

RPLP1

0.75	Ribosomal protein lateral stalk subunit P1

0.69	GO:0006414	translational elongation
0.50	GO:0032147	activation of protein kinase activity
0.49	GO:0002181	cytoplasmic translation
0.46	GO:0030218	erythrocyte differentiation
0.36	GO:0006417	regulation of translation
0.36	GO:1904401	cellular response to Thyroid stimulating hormone
0.35	GO:0071320	cellular response to cAMP
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0046907	intracellular transport
0.34	GO:0034250	positive regulation of cellular amide metabolic process

0.63	GO:0003735	structural constituent of ribosome
0.51	GO:0030295	protein kinase activator activity
0.34	GO:0043021	ribonucleoprotein complex binding
0.34	GO:0005515	protein binding
0.33	GO:0003777	microtubule motor activity
0.33	GO:0033608	formyl-CoA transferase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008144	drug binding

0.61	GO:0005840	ribosome
0.50	GO:0044445	cytosolic part
0.43	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.33	EC:2.8.3.16	GO:0033608
0.33	KEGG:R07290	GO:0033608

sp|P18860|CXA5_CHICK
Gap junction alpha-5 protein
Search

GJA5

0.64	Gap junction alpha-5 protein (Fragment)

0.61	GO:0086044	atrial cardiac muscle cell to AV node cell communication by electrical coupling
0.61	GO:0086054	bundle of His cell to Purkinje myocyte communication by electrical coupling
0.61	GO:0098906	regulation of Purkinje myocyte action potential
0.60	GO:0098905	regulation of bundle of His cell action potential
0.60	GO:0098904	regulation of AV node cell action potential
0.60	GO:0086053	AV node cell to bundle of His cell communication by electrical coupling
0.60	GO:0003193	pulmonary valve formation
0.59	GO:0098910	regulation of atrial cardiac muscle cell action potential
0.59	GO:0016264	gap junction assembly
0.59	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization

0.68	GO:0005243	gap junction channel activity
0.40	GO:0071253	connexin binding
0.39	GO:0097718	disordered domain specific binding

0.84	GO:0005922	connexin complex
0.56	GO:0014704	intercalated disc
0.47	GO:0005887	integral component of plasma membrane
0.36	GO:0042995	cell projection

sp|P18861|CXG1_CHICK
Gap junction gamma-1 protein
Search

GJC1

0.64	Gap junction gamma-1 protein (Fragment)

0.60	GO:0007154	cell communication
0.59	GO:0016264	gap junction assembly
0.56	GO:0061337	cardiac conduction
0.56	GO:0001570	vasculogenesis
0.55	GO:0048738	cardiac muscle tissue development
0.53	GO:0007601	visual perception
0.51	GO:0048468	cell development
0.44	GO:0034220	ion transmembrane transport
0.35	GO:0086002	cardiac muscle cell action potential involved in contraction
0.34	GO:0009636	response to toxic substance

0.60	GO:0086077	gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling
0.49	GO:0005216	ion channel activity
0.36	GO:0086020	gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling
0.33	GO:0005515	protein binding

0.83	GO:0005922	connexin complex
0.35	GO:0043209	myelin sheath
0.35	GO:0014704	intercalated disc
0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

sp|P18870|JUN_CHICK
Transcription factor AP-1
Search

JUN

0.94	Transcription factor jun-B

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0046686	response to cadmium ion
0.54	GO:0035026	leading edge cell differentiation
0.53	GO:0001774	microglial cell activation
0.53	GO:0009612	response to mechanical stimulus
0.52	GO:0061029	eyelid development in camera-type eye
0.52	GO:0031953	negative regulation of protein autophosphorylation
0.52	GO:0030224	monocyte differentiation

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.51	GO:0070412	R-SMAD binding
0.51	GO:0001067	regulatory region nucleic acid binding
0.51	GO:0003713	transcription coactivator activity
0.50	GO:0001102	RNA polymerase II activating transcription factor binding
0.48	GO:0031625	ubiquitin protein ligase binding
0.48	GO:0003682	chromatin binding
0.47	GO:0005096	GTPase activator activity
0.46	GO:0042803	protein homodimerization activity

0.52	GO:0035976	transcription factor AP-1 complex
0.50	GO:0005719	nuclear euchromatin
0.49	GO:0017053	transcriptional repressor complex
0.45	GO:0005654	nucleoplasm
0.36	GO:0005829	cytosol
0.33	GO:0042025	host cell nucleus
0.30	GO:0016020	membrane

sp|P18908|ANF_CHICK
Natriuretic peptides A
Search

NPPB

0.95	B-type natriuretic peptide

0.82	GO:0050880	regulation of blood vessel size
0.76	GO:0010469	regulation of receptor activity
0.49	GO:0007168	receptor guanylyl cyclase signaling pathway
0.46	GO:0006182	cGMP biosynthetic process
0.39	GO:0006457	protein folding
0.39	GO:0009792	embryo development ending in birth or egg hatching

0.79	GO:0005179	hormone activity
0.42	GO:0051427	hormone receptor binding

0.66	GO:0005576	extracellular region
0.37	GO:0043234	protein complex

sp|P18936|NU1M_CHICK
NADH-ubiquinone oxidoreductase chain 1
Search

ND1

0.47	NADH-ubiquinone oxidoreductase chain 1

0.53	GO:0055114	oxidation-reduction process
0.33	GO:0006091	generation of precursor metabolites and energy

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.37	GO:0045271	respiratory chain complex I
0.36	GO:0098798	mitochondrial protein complex
0.35	GO:1990204	oxidoreductase complex
0.31	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|P18937|NU2M_CHICK
NADH-ubiquinone oxidoreductase chain 2
Search

ND2

0.42	NADH-ubiquinone oxidoreductase chain 2

0.75	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.34	GO:0072593	reactive oxygen species metabolic process

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.34	GO:0030964	NADH dehydrogenase complex
0.34	GO:0098798	mitochondrial protein complex
0.33	GO:1990204	oxidoreductase complex
0.33	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.69

GO:0008137

sp|P18938|NU3M_CHICK
NADH-ubiquinone oxidoreductase chain 3
Search

ND3

0.47	NADH-ubiquinone oxidoreductase chain 3

0.53

GO:0055114

oxidation-reduction process

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0070469	respiratory chain
0.61	GO:0031966	mitochondrial membrane
0.36	GO:0030964	NADH dehydrogenase complex
0.35	GO:0098798	mitochondrial protein complex
0.35	GO:1990204	oxidoreductase complex
0.34	GO:0098796	membrane protein complex
0.34	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|P18939|NU4M_CHICK
NADH-ubiquinone oxidoreductase chain 4
Search

ND4

0.45	NADH-ubiquinone oxidoreductase chain 4

0.75

GO:0006120

mitochondrial electron transport, NADH to ubiquinone

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.34	GO:0070469	respiratory chain
0.34	GO:0031967	organelle envelope
0.34	GO:0031090	organelle membrane
0.34	GO:0030964	NADH dehydrogenase complex
0.33	GO:1990204	oxidoreductase complex
0.33	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.69

GO:0008137

sp|P18940|NU5M_CHICK
NADH-ubiquinone oxidoreductase chain 5
Search

ND5

0.48	NADH-ubiquinone oxidoreductase chain 5

0.69

GO:0042773

ATP synthesis coupled electron transport

0.68

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0070469	respiratory chain
0.61	GO:0031966	mitochondrial membrane
0.61	GO:0019866	organelle inner membrane
0.37	GO:0030964	NADH dehydrogenase complex
0.36	GO:0098798	mitochondrial protein complex
0.36	GO:1990204	oxidoreductase complex
0.35	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.68

GO:0008137

sp|P18941|NU6M_CHICK
NADH-ubiquinone oxidoreductase chain 6
Search

ND6

0.49	NADH-ubiquinone oxidoreductase chain 6

0.53

GO:0055114

oxidation-reduction process

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.33	GO:0070469	respiratory chain
0.33	GO:0031967	organelle envelope
0.33	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|P18942|NU4LM_CHICK
NADH-ubiquinone oxidoreductase chain 4L
Search

ND4L

0.50	NADH-ubiquinone oxidoreductase chain 4L

0.69

GO:0042773

ATP synthesis coupled electron transport

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.34	GO:0045271	respiratory chain complex I
0.34	GO:0031967	organelle envelope
0.34	GO:0031090	organelle membrane
0.33	GO:1990204	oxidoreductase complex
0.30	GO:0016021	integral component of membrane

0.69

GO:0008137

sp|P18943|COX1_CHICK
Cytochrome c oxidase subunit 1
Search

COX1

0.43	Cytochrome c oxidase subunit 1

0.64	GO:0006119	oxidative phosphorylation
0.64	GO:0009060	aerobic respiration
0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0020037	heme binding
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.63	GO:0005506	iron ion binding
0.62	GO:0009055	electron transfer activity

0.74	GO:0045277	respiratory chain complex IV
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.35	GO:0098798	mitochondrial protein complex
0.35	GO:0045275	respiratory chain complex III
0.30	GO:0016021	integral component of membrane

0.65

EC:1.9.3

GO:0016676

sp|P18944|COX2_CHICK
Cytochrome c oxidase subunit 2
Search

COX2

0.40	Cytochrome c oxidase subunit 2

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.33	GO:0006979	response to oxidative stress
0.33	GO:0006119	oxidative phosphorylation
0.33	GO:0045333	cellular respiration

0.72	GO:0005507	copper ion binding
0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.37	GO:0070069	cytochrome complex
0.35	GO:0098796	membrane protein complex
0.34	GO:0098798	mitochondrial protein complex
0.30	GO:0016021	integral component of membrane

0.65

EC:1.9.3

GO:0016676

sp|P18945|COX3_CHICK
Cytochrome c oxidase subunit 3
Search

COX3

0.44	Cytochrome c oxidase subunit 3

0.76	GO:0019646	aerobic electron transport chain
0.63	GO:1902600	hydrogen ion transmembrane transport
0.37	GO:0008535	respiratory chain complex IV assembly

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.61	GO:0005739	mitochondrion
0.37	GO:0045277	respiratory chain complex IV
0.34	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.65

EC:1.9.3

GO:0016676

sp|P18946|CYB_CHICK
Cytochrome b
Search

CYTB

0.41	Cytochrome b

0.73	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c
0.33	GO:0006979	response to oxidative stress

0.73	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.62	GO:0009055	electron transfer activity
0.53	GO:0046872	metal ion binding
0.33	GO:0020037	heme binding

0.72	GO:0045275	respiratory chain complex III
0.61	GO:0031966	mitochondrial membrane
0.61	GO:0019866	organelle inner membrane
0.35	GO:0031301	integral component of organelle membrane
0.34	GO:0098798	mitochondrial protein complex

0.73

EC:1.10.2

GO:0016681

sp|P19019|GBRB3_CHICK
Gamma-aminobutyric acid receptor subunit beta-3
Search

GABRB3

0.91	Testis gamma-aminobutyric acid receptor subunit beta 3

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.56	GO:0071420	cellular response to histamine
0.54	GO:0060384	innervation
0.53	GO:0090102	cochlea development
0.53	GO:0060119	inner ear receptor cell development
0.52	GO:0060021	palate development
0.52	GO:0043524	negative regulation of neuron apoptotic process
0.51	GO:0007605	sensory perception of sound
0.50	GO:0060078	regulation of postsynaptic membrane potential

0.84	GO:0004890	GABA-A receptor activity
0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.54	GO:0099095	ligand-gated anion channel activity
0.49	GO:0005254	chloride channel activity
0.49	GO:0022835	transmitter-gated channel activity
0.48	GO:0042802	identical protein binding
0.35	GO:0035612	AP-2 adaptor complex binding

0.58	GO:1902711	GABA-A receptor complex
0.56	GO:0005886	plasma membrane
0.49	GO:0098794	postsynapse
0.39	GO:0034707	chloride channel complex
0.38	GO:0030659	cytoplasmic vesicle membrane
0.37	GO:0030054	cell junction
0.37	GO:0060077	inhibitory synapse
0.35	GO:0043195	terminal bouton

sp|P19098|CP19A_CHICK
Aromatase
Search

CYP19A1

0.79	LOW QUALITY PROTEIN: aromatase

0.61	GO:2000866	positive regulation of estradiol secretion
0.60	GO:0006710	androgen catabolic process
0.59	GO:0002677	negative regulation of chronic inflammatory response
0.59	GO:0010760	negative regulation of macrophage chemotaxis
0.59	GO:0061370	testosterone biosynthetic process
0.58	GO:0060736	prostate gland growth
0.58	GO:0030540	female genitalia development
0.58	GO:0060065	uterus development
0.56	GO:0008585	female gonad development
0.53	GO:0030879	mammary gland development

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.65	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.34	GO:0019825	oxygen binding
0.33	GO:0009055	electron transfer activity

0.49	GO:0005783	endoplasmic reticulum
0.39	GO:0044297	cell body
0.38	GO:0043195	terminal bouton
0.38	GO:0030425	dendrite
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0044309	neuron spine
0.34	GO:0031984	organelle subcompartment
0.34	GO:0008021	synaptic vesicle
0.34	GO:0098794	postsynapse
0.33	GO:0005829	cytosol

0.68

EC:1.14

GO:0016705

sp|P19121|ALBU_CHICK
Serum albumin
Search

ALB

0.92	serum albumin precursor

0.55	GO:0051659	maintenance of mitochondrion location
0.52	GO:0019836	hemolysis by symbiont of host erythrocytes
0.48	GO:0009267	cellular response to starvation
0.48	GO:0043066	negative regulation of apoptotic process
0.48	GO:0001542	ovulation from ovarian follicle
0.48	GO:0042448	progesterone metabolic process
0.46	GO:0060395	SMAD protein signal transduction
0.37	GO:0007584	response to nutrient
0.36	GO:0071693	protein transport within extracellular region
0.36	GO:0010033	response to organic substance

0.52	GO:0005504	fatty acid binding
0.50	GO:0015643	toxic substance binding
0.49	GO:0019825	oxygen binding
0.45	GO:0051087	chaperone binding
0.44	GO:0030170	pyridoxal phosphate binding
0.44	GO:0042802	identical protein binding
0.40	GO:0003677	DNA binding
0.38	GO:0046872	metal ion binding
0.36	GO:0008431	vitamin E binding
0.34	GO:0004817	cysteine-tRNA ligase activity

0.73	GO:0005615	extracellular space
0.46	GO:0043209	myelin sheath
0.46	GO:1903561	extracellular vesicle
0.43	GO:0005794	Golgi apparatus
0.43	GO:0005783	endoplasmic reticulum
0.41	GO:0043234	protein complex
0.37	GO:0060417	yolk
0.34	GO:0005604	basement membrane
0.33	GO:0043233	organelle lumen
0.33	GO:0005634	nucleus

0.34

EC:6.1.1.16

GO:0004817

sp|P19150|GBRA1_CHICK
Gamma-aminobutyric acid receptor subunit alpha-1
Search

GABRA1

0.97	Gamma-aminobutyric acid receptor subunit alpha-1

0.81	GO:0007214	gamma-aminobutyric acid signaling pathway
0.73	GO:0006821	chloride transport
0.60	GO:0034220	ion transmembrane transport
0.52	GO:0060078	regulation of postsynaptic membrane potential
0.40	GO:0071420	cellular response to histamine
0.40	GO:0051932	synaptic transmission, GABAergic
0.36	GO:0006836	neurotransmitter transport
0.35	GO:0001505	regulation of neurotransmitter levels

0.83	GO:0004890	GABA-A receptor activity
0.75	GO:0005230	extracellular ligand-gated ion channel activity
0.56	GO:0099095	ligand-gated anion channel activity
0.53	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
0.52	GO:0005254	chloride channel activity
0.52	GO:0022835	transmitter-gated channel activity
0.40	GO:0008503	benzodiazepine receptor activity
0.34	GO:0008144	drug binding
0.34	GO:0005515	protein binding

0.59	GO:1902711	GABA-A receptor complex
0.55	GO:0005886	plasma membrane
0.46	GO:0098794	postsynapse
0.45	GO:0060077	inhibitory synapse
0.43	GO:0034707	chloride channel complex
0.42	GO:0043025	neuronal cell body
0.42	GO:0030425	dendrite
0.42	GO:0030424	axon
0.41	GO:0030054	cell junction
0.41	GO:0030659	cytoplasmic vesicle membrane

sp|P19179|PLSI_CHICK
Plastin-1
Search

PLS1

0.86

L-plastin

0.58	GO:1902896	terminal web assembly
0.57	GO:0001951	intestinal D-glucose absorption
0.57	GO:0032532	regulation of microvillus length
0.55	GO:0040018	positive regulation of multicellular organism growth
0.54	GO:1903078	positive regulation of protein localization to plasma membrane
0.52	GO:0051017	actin filament bundle assembly
0.52	GO:0051639	actin filament network formation
0.51	GO:0051764	actin crosslink formation
0.44	GO:0001501	skeletal system development
0.43	GO:0071803	positive regulation of podosome assembly

0.74	GO:0003779	actin binding
0.69	GO:0005509	calcium ion binding
0.68	GO:0032403	protein complex binding
0.41	GO:0050839	cell adhesion molecule binding
0.40	GO:0042802	identical protein binding
0.40	GO:0051020	GTPase binding
0.39	GO:0005102	receptor binding
0.34	GO:0005262	calcium channel activity
0.34	GO:0005200	structural constituent of cytoskeleton

0.56	GO:1990357	terminal web
0.54	GO:0005903	brush border
0.52	GO:0032432	actin filament bundle
0.52	GO:0005884	actin filament
0.44	GO:0001891	phagocytic cup
0.43	GO:0005829	cytosol
0.43	GO:0002102	podosome
0.42	GO:0001726	ruffle
0.42	GO:0042641	actomyosin
0.42	GO:0030175	filopodium

sp|P19204|CASQ2_CHICK
Calsequestrin-2
Search

CASQ2

0.91	Calsequestrin

0.57	GO:0051208	sequestering of calcium ion
0.57	GO:0071313	cellular response to caffeine
0.57	GO:0010649	regulation of cell communication by electrical coupling
0.56	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
0.56	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
0.55	GO:1901017	negative regulation of potassium ion transmembrane transporter activity
0.55	GO:0060306	regulation of membrane repolarization
0.54	GO:0060048	cardiac muscle contraction
0.54	GO:0002027	regulation of heart rate
0.53	GO:0045214	sarcomere organization

0.70	GO:0005509	calcium ion binding
0.54	GO:0048306	calcium-dependent protein binding
0.35	GO:0042803	protein homodimerization activity
0.35	GO:0005080	protein kinase C binding
0.32	GO:0016887	ATPase activity
0.32	GO:0005524	ATP binding

0.58	GO:0033018	sarcoplasmic reticulum lumen
0.55	GO:0030314	junctional membrane complex
0.53	GO:0030018	Z disc
0.43	GO:0014802	terminal cisterna
0.36	GO:0005891	voltage-gated calcium channel complex
0.35	GO:0014701	junctional sarcoplasmic reticulum membrane

0.32

GO:0016887

sp|P19336|CYR61_CHICK
Protein CYR61
Search

CYR61

0.96	Cysteine rich angiogenic inducer 61

0.78	GO:0001558	regulation of cell growth
0.63	GO:0002041	intussusceptive angiogenesis
0.62	GO:2000304	positive regulation of ceramide biosynthetic process
0.62	GO:0003278	apoptotic process involved in heart morphogenesis
0.61	GO:0060591	chondroblast differentiation
0.61	GO:0033690	positive regulation of osteoblast proliferation
0.60	GO:0060413	atrial septum morphogenesis
0.60	GO:0003181	atrioventricular valve morphogenesis
0.60	GO:0090505	epiboly involved in wound healing
0.59	GO:0010518	positive regulation of phospholipase activity

0.83	GO:0005520	insulin-like growth factor binding
0.59	GO:0005178	integrin binding
0.57	GO:0050840	extracellular matrix binding
0.47	GO:0008201	heparin binding
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.66	GO:0005576	extracellular region
0.35	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

sp|P19352|TPM2_CHICK
Tropomyosin beta chain
Search

TPM2

0.31	Tropomyosin beta chain

0.67	GO:0043462	regulation of ATPase activity
0.63	GO:0006936	muscle contraction
0.58	GO:0007015	actin filament organization
0.41	GO:0033275	actin-myosin filament sliding
0.39	GO:0007016	cytoskeletal anchoring at plasma membrane
0.37	GO:0007155	cell adhesion

0.69	GO:0003779	actin binding
0.67	GO:0008307	structural constituent of muscle
0.61	GO:0032403	protein complex binding
0.50	GO:0042803	protein homodimerization activity
0.50	GO:0046982	protein heterodimerization activity
0.41	GO:0005200	structural constituent of cytoskeleton

0.71	GO:0005865	striated muscle thin filament
0.63	GO:0005884	actin filament
0.38	GO:0001726	ruffle
0.38	GO:0005925	focal adhesion
0.37	GO:0005829	cytosol

sp|P19439|GLRK_CHICK
Probable glutamate receptor
Search

0.83	Kainate receptor alpha subunit

0.80	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.60	GO:0034220	ion transmembrane transport
0.41	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration
0.40	GO:0060292	long term synaptic depression
0.40	GO:0031623	receptor internalization
0.40	GO:0007616	long-term memory
0.36	GO:0016042	lipid catabolic process
0.35	GO:0035556	intracellular signal transduction
0.33	GO:0001661	conditioned taste aversion

0.82	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.41	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
0.40	GO:0099094	ligand-gated cation channel activity
0.39	GO:1904315	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
0.37	GO:0004435	phosphatidylinositol phospholipase C activity
0.36	GO:0005509	calcium ion binding
0.33	GO:0001540	amyloid-beta binding
0.33	GO:0030165	PDZ domain binding

0.78	GO:0098794	postsynapse
0.58	GO:0097060	synaptic membrane
0.56	GO:0030054	cell junction
0.41	GO:0032281	AMPA glutamate receptor complex
0.41	GO:0044308	axonal spine
0.40	GO:0032590	dendrite membrane
0.40	GO:0032279	asymmetric synapse
0.39	GO:0055037	recycling endosome
0.39	GO:0008021	synaptic vesicle
0.39	GO:0043025	neuronal cell body

0.37	EC:3.1.4.11	GO:0004435
0.37	KEGG:R03435	GO:0004435

sp|P19596|FGF1_CHICK
Fibroblast growth factor 1
Search

FGF1

0.53	Fibroblast growth factor 1

0.83	GO:0008543	fibroblast growth factor receptor signaling pathway
0.75	GO:0010469	regulation of receptor activity
0.62	GO:0001525	angiogenesis
0.60	GO:0045766	positive regulation of angiogenesis
0.59	GO:0051781	positive regulation of cell division
0.58	GO:0001759	organ induction
0.58	GO:0010595	positive regulation of endothelial cell migration
0.57	GO:0042127	regulation of cell proliferation
0.57	GO:0035295	tube development
0.56	GO:0072088	nephron epithelium morphogenesis

0.84	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.59	GO:0008201	heparin binding
0.53	GO:0044548	S100 protein binding
0.52	GO:0005178	integrin binding
0.41	GO:0030544	Hsp70 protein binding
0.39	GO:0090722	receptor-receptor interaction
0.39	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.38	GO:0042056	chemoattractant activity
0.38	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity

0.66	GO:0005576	extracellular region
0.52	GO:0005938	cell cortex
0.48	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.38	GO:0070013	intracellular organelle lumen
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.39	EC:2.7.1.153	GO:0046934
0.39	KEGG:R04545	GO:0046934

sp|P19601|SAX1_CHICK
Homeobox protein SAX-1 (Fragment)
Search

0.85	Homeobox protein SAX-1 (Fragment)

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.41	GO:0032501	multicellular organismal process
0.40	GO:0010906	regulation of glucose metabolic process
0.40	GO:0043467	regulation of generation of precursor metabolites and energy
0.38	GO:0048856	anatomical structure development
0.36	GO:0006629	lipid metabolic process
0.34	GO:0001709	cell fate determination
0.34	GO:0001708	cell fate specification

0.64	GO:0043565	sequence-specific DNA binding
0.34	GO:0004000	adenosine deaminase activity
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

EC:3.5.4.4

GO:0004000

sp|P19753|PRVT_CHICK
Parvalbumin, thymic
Search

0.88	Novel protein containing two EF hand domains

0.70

GO:0005509

calcium ion binding

0.34	GO:0043679	axon terminus
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon

sp|P19850|TKNA_CHICK
Substance P
Search

0.10	Substance P

0.30	GO:0065007	biological regulation
0.30	GO:0050896	response to stimulus
0.30	GO:0009987	cellular process
0.30	GO:0023052	signaling

0.30

GO:0005576

extracellular region

sp|P19851|TKNB_CHICK
Neurokinin-A
Search

0.10	Neurokinin-A

0.30	GO:0065007	biological regulation
0.30	GO:0050896	response to stimulus
0.30	GO:0009987	cellular process
0.30	GO:0023052	signaling

0.30

GO:0005576

extracellular region

sp|P19966|TAGL_CHICK
Transgelin
Search

TAGLN

0.82	Transgelin

0.53	GO:0030855	epithelial cell differentiation
0.43	GO:0007010	cytoskeleton organization
0.42	GO:0030029	actin filament-based process
0.39	GO:0000902	cell morphogenesis
0.39	GO:1904706	negative regulation of vascular smooth muscle cell proliferation
0.37	GO:0033227	dsRNA transport
0.35	GO:0007517	muscle organ development
0.32	GO:0006940	regulation of smooth muscle contraction

0.74	GO:0051015	actin filament binding
0.40	GO:0005516	calmodulin binding
0.37	GO:0051032	nucleic acid transmembrane transporter activity
0.35	GO:0030674	protein binding, bridging

0.40	GO:0005856	cytoskeleton
0.34	GO:0005737	cytoplasm
0.33	GO:0005925	focal adhesion
0.30	GO:0016020	membrane

sp|P20057|HEMO_CHICK
Hemopexin (Fragment)
Search

0.78	Hemopexin (Fragment)

0.54

GO:0046872

metal ion binding

0.66

GO:0005576

extracellular region

sp|P20111|ACTN2_CHICK
Alpha-actinin-2
Search

ACTN2

0.96	Alpha-actinin-2

0.59	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway
0.59	GO:0045214	sarcomere organization
0.58	GO:0030035	microspike assembly
0.58	GO:2001137	positive regulation of endocytic recycling
0.57	GO:0048041	focal adhesion assembly
0.57	GO:2000009	negative regulation of protein localization to cell surface
0.56	GO:1901017	negative regulation of potassium ion transmembrane transporter activity
0.56	GO:0014706	striated muscle tissue development
0.56	GO:0051695	actin filament uncapping
0.56	GO:1901018	positive regulation of potassium ion transmembrane transporter activity

0.73	GO:0003779	actin binding
0.69	GO:0005509	calcium ion binding
0.59	GO:0070080	titin Z domain binding
0.58	GO:0030375	thyroid hormone receptor coactivator activity
0.58	GO:0051373	FATZ binding
0.57	GO:0031432	titin binding
0.56	GO:0030274	LIM domain binding
0.55	GO:0044325	ion channel binding
0.54	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.50	GO:0032403	protein complex binding

0.55	GO:0030018	Z disc
0.54	GO:0030175	filopodium
0.53	GO:0005925	focal adhesion
0.41	GO:0005886	plasma membrane
0.37	GO:0030864	cortical actin cytoskeleton
0.36	GO:0005884	actin filament
0.36	GO:0005903	brush border
0.36	GO:0070062	extracellular exosome
0.35	GO:0031093	platelet alpha granule lumen
0.35	GO:0005916	fascia adherens

sp|P20135|GSTT1_CHICK
Glutathione S-transferase theta-1
Search

0.90	Glutathione S-transferase theta-1

0.46	GO:0006749	glutathione metabolic process
0.35	GO:1990830	cellular response to leukemia inhibitory factor
0.34	GO:0006336	DNA replication-independent nucleosome assembly
0.34	GO:0018900	dichloromethane metabolic process
0.34	GO:1901687	glutathione derivative biosynthetic process
0.33	GO:0033197	response to vitamin E
0.33	GO:0010269	response to selenium ion
0.33	GO:0098869	cellular oxidant detoxification
0.33	GO:0009751	response to salicylic acid
0.32	GO:0006304	DNA modification

0.50	GO:0016740	transferase activity
0.34	GO:0004386	helicase activity
0.34	GO:0004602	glutathione peroxidase activity
0.34	GO:0047651	alkylhalidase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003676	nucleic acid binding
0.32	GO:0005515	protein binding

0.36	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.33	GO:0070062	extracellular exosome

0.50	EC:2	GO:0016740
0.34	KEGG:R03523	GO:0047651

sp|P20136|GSTM2_CHICK
Glutathione S-transferase 2
Search

0.42	Glutathione S-transferase mu

0.55	GO:0018916	nitrobenzene metabolic process
0.50	GO:0070458	cellular detoxification of nitrogen compound
0.49	GO:0006749	glutathione metabolic process
0.49	GO:0042178	xenobiotic catabolic process
0.46	GO:0043627	response to estrogen
0.39	GO:1901685	glutathione derivative metabolic process
0.35	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity
0.35	GO:0008065	establishment of blood-nerve barrier
0.35	GO:0071313	cellular response to caffeine
0.35	GO:0044272	sulfur compound biosynthetic process

0.78	GO:0004364	glutathione transferase activity
0.52	GO:0043295	glutathione binding
0.48	GO:0042802	identical protein binding
0.46	GO:0019899	enzyme binding
0.45	GO:0046983	protein dimerization activity
0.34	GO:0004602	glutathione peroxidase activity
0.34	GO:0016223	beta-alanine-pyruvate transaminase activity
0.34	GO:0005102	receptor binding

0.54	GO:0045171	intercellular bridge
0.48	GO:0035686	sperm fibrous sheath
0.47	GO:0005829	cytosol
0.35	GO:0016529	sarcoplasmic reticulum
0.34	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus

0.78

GO:0004364

sp|P20137|GST5_CHICK
Glutathione S-transferase 5 (Fragment)
Search

0.80	Glutathione S-transferase 5 (Fragment)

0.42	GO:0006692	prostanoid metabolic process
0.37	GO:0045087	innate immune response

0.64	GO:0004364	glutathione transferase activity
0.44	GO:0004667	prostaglandin-D synthase activity
0.40	GO:0042803	protein homodimerization activity
0.39	GO:0005509	calcium ion binding
0.38	GO:0000287	magnesium ion binding

0.33

GO:0005737

cytoplasm

0.64	EC:2.5.1.18	GO:0004364
0.44	KEGG:R02266	GO:0004667

sp|P20307|KRFD_CHICK
Feather keratin 3
Search

0.81	Feather beta keratin

0.71	GO:0007010	cytoskeleton organization
0.34	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.77	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0004984	olfactory receptor activity

0.79	GO:0005882	intermediate filament
0.30	GO:0031224	intrinsic component of membrane

sp|P20308|KRFA_CHICK
Feather keratin 4
Search

0.82	Feather beta keratin

0.71

GO:0007010

cytoskeleton organization

0.77

GO:0005200

structural constituent of cytoskeleton

0.79

GO:0005882

intermediate filament

sp|P20678|CP2H2_CHICK
Cytochrome P450 2H2
Search

CYP2C8

0.97	Cytochrome P450 family 2 subfamily C member 9

0.55	GO:0019373	epoxygenase P450 pathway
0.53	GO:0055114	oxidation-reduction process
0.47	GO:0042738	exogenous drug catabolic process
0.43	GO:0008202	steroid metabolic process
0.43	GO:0016098	monoterpenoid metabolic process
0.42	GO:0070988	demethylation
0.42	GO:0002933	lipid hydroxylation
0.38	GO:0043651	linoleic acid metabolic process
0.37	GO:0097267	omega-hydroxylase P450 pathway
0.37	GO:0019627	urea metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.46	GO:0034875	caffeine oxidase activity
0.37	GO:0019825	oxygen binding
0.36	GO:0019899	enzyme binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0004713	protein tyrosine kinase activity
0.31	GO:0030554	adenyl nucleotide binding

0.42	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

EC:1.14

GO:0016705

sp|P20740|OVOS_CHICK
Ovostatin
Search

A2M

0.68	Alpha-2-macroglobulin

0.76	GO:0010951	negative regulation of endopeptidase activity
0.46	GO:0001869	negative regulation of complement activation, lectin pathway
0.37	GO:0048863	stem cell differentiation
0.35	GO:0032501	multicellular organismal process
0.35	GO:0009611	response to wounding
0.35	GO:0022414	reproductive process
0.35	GO:0002438	acute inflammatory response to antigenic stimulus
0.35	GO:0002576	platelet degranulation
0.35	GO:0010037	response to carbon dioxide
0.35	GO:0022617	extracellular matrix disassembly

0.77	GO:0004866	endopeptidase inhibitor activity
0.46	GO:0043120	tumor necrosis factor binding
0.45	GO:0019959	interleukin-8 binding
0.45	GO:0019966	interleukin-1 binding
0.44	GO:0048306	calcium-dependent protein binding
0.43	GO:0002020	protease binding
0.40	GO:0005102	receptor binding
0.36	GO:0048403	brain-derived neurotrophic factor binding
0.36	GO:0048406	nerve growth factor binding
0.34	GO:0005096	GTPase activator activity

0.73	GO:0005615	extracellular space
0.35	GO:1903561	extracellular vesicle
0.35	GO:0031093	platelet alpha granule lumen
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P20763|LAC_CHICK
Ig lambda chain C region
Search

0.97	Ig lambda chain C regions

0.73	GO:0002250	adaptive immune response
0.71	GO:0006910	phagocytosis, recognition
0.71	GO:0002449	lymphocyte mediated immunity
0.70	GO:0006911	phagocytosis, engulfment
0.70	GO:0006956	complement activation
0.70	GO:0050853	B cell receptor signaling pathway
0.69	GO:0050871	positive regulation of B cell activation
0.65	GO:0045087	innate immune response
0.64	GO:0042742	defense response to bacterium
0.52	GO:0002377	immunoglobulin production

0.78	GO:0003823	antigen binding
0.72	GO:0034987	immunoglobulin receptor binding
0.40	GO:0004252	serine-type endopeptidase activity

0.73	GO:0072562	blood microparticle
0.71	GO:0042571	immunoglobulin complex, circulating
0.67	GO:0009897	external side of plasma membrane
0.49	GO:0070062	extracellular exosome

0.40

GO:0004252

sp|P20785|CO6A1_CHICK
Collagen alpha-1(VI) chain
Search

COL6A1

0.82	Collagen type VI alpha 1 chain

0.63	GO:0070208	protein heterotrimerization
0.60	GO:0035987	endodermal cell differentiation
0.59	GO:0071230	cellular response to amino acid stimulus
0.41	GO:0007155	cell adhesion
0.37	GO:0001649	osteoblast differentiation
0.36	GO:0006979	response to oxidative stress
0.36	GO:0098869	cellular oxidant detoxification
0.35	GO:0009749	response to glucose
0.34	GO:0030574	collagen catabolic process
0.34	GO:0055114	oxidation-reduction process

0.62	GO:0048407	platelet-derived growth factor binding
0.37	GO:0004601	peroxidase activity
0.35	GO:0020037	heme binding

0.70	GO:0005581	collagen trimer
0.60	GO:0042383	sarcolemma
0.57	GO:0005578	proteinaceous extracellular matrix
0.54	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:0005765	lysosomal membrane
0.35	GO:0098647	collagen beaded filament
0.34	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

0.37	EC:1.11.1.7	GO:0004601
0.37	KEGG:R03532	GO:0004601

sp|P21265|PUR8_CHICK
Adenylosuccinate lyase
Search

ADSL

0.48	Adenylosuccinate lyase

0.74	GO:0044208	'de novo' AMP biosynthetic process
0.68	GO:0006189	'de novo' IMP biosynthetic process
0.51	GO:0051262	protein tetramerization
0.39	GO:0014850	response to muscle activity
0.38	GO:0001666	response to hypoxia
0.38	GO:0007584	response to nutrient
0.37	GO:0042594	response to starvation
0.35	GO:0009060	aerobic respiration

0.78	GO:0004018	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity
0.76	GO:0070626	(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity

0.47	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion

0.78	EC:4.3.2.2	GO:0004018
0.78	KEGG:R01083	GO:0004018

sp|P21548|GBRG2_CHICK
Gamma-aminobutyric acid receptor subunit gamma-2
Search

GABRG2

0.95	Gamma-aminobutyric acid receptor subunit epsilon

0.85	GO:0007214	gamma-aminobutyric acid signaling pathway
0.77	GO:0006821	chloride transport
0.60	GO:0034220	ion transmembrane transport
0.56	GO:0071420	cellular response to histamine
0.52	GO:0030534	adult behavior
0.50	GO:0009791	post-embryonic development
0.50	GO:0007268	chemical synaptic transmission

0.84	GO:0004890	GABA-A receptor activity
0.75	GO:0005230	extracellular ligand-gated ion channel activity
0.50	GO:0005254	chloride channel activity
0.36	GO:0008503	benzodiazepine receptor activity
0.35	GO:0005515	protein binding

0.55	GO:0005886	plasma membrane
0.55	GO:1902711	GABA-A receptor complex
0.51	GO:0030424	axon
0.40	GO:0034707	chloride channel complex
0.40	GO:0098794	postsynapse
0.39	GO:0030425	dendrite
0.39	GO:0030054	cell junction
0.38	GO:0030659	cytoplasmic vesicle membrane
0.37	GO:0060077	inhibitory synapse
0.36	GO:0031252	cell leading edge

sp|P21566|COF2_CHICK
Cofilin-2
Search

CFL2

0.96	Cofilin 2 homolog (Predicted)

0.84	GO:0030042	actin filament depolymerization
0.59	GO:0030836	positive regulation of actin filament depolymerization
0.55	GO:0046716	muscle cell cellular homeostasis
0.54	GO:0045214	sarcomere organization
0.53	GO:0007519	skeletal muscle tissue development
0.46	GO:0001842	neural fold formation
0.45	GO:0001755	neural crest cell migration
0.44	GO:0043200	response to amino acid
0.44	GO:0044794	positive regulation by host of viral process
0.43	GO:0061001	regulation of dendritic spine morphogenesis

0.74	GO:0003779	actin binding
0.54	GO:0032403	protein complex binding
0.41	GO:0005102	receptor binding
0.37	GO:0019903	protein phosphatase binding
0.37	GO:1902936	phosphatidylinositol bisphosphate binding
0.34	GO:0046872	metal ion binding

0.74	GO:0015629	actin cytoskeleton
0.54	GO:0030018	Z disc
0.45	GO:0030027	lamellipodium
0.45	GO:0016363	nuclear matrix
0.43	GO:0030863	cortical cytoskeleton
0.42	GO:0005615	extracellular space
0.42	GO:0005911	cell-cell junction
0.40	GO:0032587	ruffle membrane
0.40	GO:0044430	cytoskeletal part
0.38	GO:1903561	extracellular vesicle

sp|P21611|B2MG_CHICK
Beta-2-microglobulin
Search

B2M

0.80	Beta-2-microglobulin

0.81	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
0.74	GO:0006955	immune response
0.53	GO:1904437	positive regulation of transferrin receptor binding
0.53	GO:1904440	positive regulation of ferrous iron import across plasma membrane
0.53	GO:1904432	regulation of ferrous iron binding
0.52	GO:0071283	cellular response to iron(III) ion
0.52	GO:0002481	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
0.51	GO:0002726	positive regulation of T cell cytokine production
0.51	GO:1900121	negative regulation of receptor binding
0.51	GO:0033216	ferric iron import

0.45	GO:0042802	identical protein binding
0.33	GO:0046872	metal ion binding

0.81	GO:0042612	MHC class I protein complex
0.66	GO:0005576	extracellular region
0.51	GO:1990712	HFE-transferrin receptor complex
0.47	GO:0009897	external side of plasma membrane
0.45	GO:0005794	Golgi apparatus
0.44	GO:0005829	cytosol

sp|P21642|PCKGM_CHICK
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial
Search

PCK2

0.69	Acipenser baerii mitochondrial phosphoenolpyruvate carboxykinase mRNA

0.73	GO:0019319	hexose biosynthetic process
0.71	GO:0006006	glucose metabolic process
0.49	GO:0016310	phosphorylation
0.45	GO:1901700	response to oxygen-containing compound
0.44	GO:0010033	response to organic substance
0.44	GO:0046327	glycerol biosynthetic process from pyruvate
0.43	GO:0061402	positive regulation of transcription from RNA polymerase II promoter in response to acidic pH
0.43	GO:0051365	cellular response to potassium ion starvation
0.43	GO:0009719	response to endogenous stimulus
0.41	GO:0048878	chemical homeostasis

0.83	GO:0004613	phosphoenolpyruvate carboxykinase (GTP) activity
0.66	GO:0005525	GTP binding
0.51	GO:0016301	kinase activity
0.40	GO:0030145	manganese ion binding
0.39	GO:0043177	organic acid binding
0.38	GO:0000287	magnesium ion binding
0.36	GO:0019003	GDP binding
0.35	GO:0047134	protein-disulfide reductase activity
0.35	GO:0004457	lactate dehydrogenase activity
0.35	GO:0019904	protein domain specific binding

0.43	GO:0005739	mitochondrion
0.38	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part

0.83

EC:4.1.1.32

GO:0004613

sp|P21760|EXFAB_CHICK
Extracellular fatty acid-binding protein
Search

EXFABP

0.96	Extracellular fatty acid-binding protein

0.83	GO:0071399	cellular response to linoleic acid
0.76	GO:0051412	response to corticosterone
0.74	GO:0055089	fatty acid homeostasis
0.74	GO:0032332	positive regulation of chondrocyte differentiation
0.73	GO:0010831	positive regulation of myotube differentiation
0.73	GO:0045663	positive regulation of myoblast differentiation
0.72	GO:0006953	acute-phase response
0.72	GO:0009617	response to bacterium
0.67	GO:0015908	fatty acid transport
0.66	GO:0007507	heart development

0.85	GO:0070538	oleic acid binding
0.84	GO:0050544	arachidonic acid binding
0.82	GO:0070540	stearic acid binding
0.78	GO:0070539	linoleic acid binding
0.65	GO:1903981	enterobactin binding

0.62	GO:0005576	extracellular region
0.30	GO:0005623	cell

sp|P21804|FGFR1_CHICK
Fibroblast growth factor receptor 1
Search

FGFR1

0.74	Fibroblast growth factor receptor

0.82	GO:0008543	fibroblast growth factor receptor signaling pathway
0.78	GO:0008284	positive regulation of cell proliferation
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.58	GO:2000830	positive regulation of parathyroid hormone secretion
0.58	GO:0021769	orbitofrontal cortex development
0.58	GO:0048378	regulation of lateral mesodermal cell fate specification
0.57	GO:0021847	ventricular zone neuroblast division
0.57	GO:1903465	positive regulation of mitotic cell cycle DNA replication
0.57	GO:1904849	positive regulation of cell chemotaxis to fibroblast growth factor
0.57	GO:0090272	negative regulation of fibroblast growth factor production

0.85	GO:0005007	fibroblast growth factor-activated receptor activity
0.57	GO:0090722	receptor-receptor interaction
0.55	GO:0017134	fibroblast growth factor binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0008201	heparin binding
0.53	GO:0008144	drug binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0042803	protein homodimerization activity
0.35	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity

0.51	GO:0043235	receptor complex
0.48	GO:0005730	nucleolus
0.42	GO:0005886	plasma membrane
0.39	GO:0031410	cytoplasmic vesicle
0.38	GO:0005829	cytosol
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

sp|P21805|ANFC_CHICK
C-type natriuretic peptide
Search

0.72	C-type natriuretic peptide

0.81	GO:0050880	regulation of blood vessel size
0.76	GO:0010469	regulation of receptor activity
0.56	GO:0007168	receptor guanylyl cyclase signaling pathway
0.55	GO:0003419	growth plate cartilage chondrocyte proliferation
0.54	GO:0003418	growth plate cartilage chondrocyte differentiation
0.53	GO:1900194	negative regulation of oocyte maturation
0.53	GO:0006182	cGMP biosynthetic process
0.51	GO:0030823	regulation of cGMP metabolic process
0.50	GO:0030814	regulation of cAMP metabolic process
0.50	GO:0051447	negative regulation of meiotic cell cycle

0.79	GO:0005179	hormone activity
0.50	GO:0051427	hormone receptor binding
0.41	GO:0090729	toxin activity
0.40	GO:0008191	metalloendopeptidase inhibitor activity
0.37	GO:0042803	protein homodimerization activity

0.66	GO:0005576	extracellular region
0.41	GO:0043234	protein complex
0.38	GO:0030141	secretory granule
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P21868|CSK21_CHICK
Casein kinase II subunit alpha
Search

CSNK2A1

0.77	Casein kinase II subunit alpha

0.63	GO:0006468	protein phosphorylation
0.44	GO:0030307	positive regulation of cell growth
0.43	GO:0045732	positive regulation of protein catabolic process
0.43	GO:0008284	positive regulation of cell proliferation
0.42	GO:0051336	regulation of hydrolase activity
0.42	GO:0032268	regulation of cellular protein metabolic process
0.42	GO:0030177	positive regulation of Wnt signaling pathway
0.41	GO:0035303	regulation of dephosphorylation
0.41	GO:1905818	regulation of chromosome separation
0.40	GO:0043066	negative regulation of apoptotic process

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0008013	beta-catenin binding
0.42	GO:0019888	protein phosphatase regulator activity
0.41	GO:0047485	protein N-terminus binding
0.38	GO:0042802	identical protein binding
0.36	GO:0043021	ribonucleoprotein complex binding
0.35	GO:0051879	Hsp90 protein binding

0.42	GO:0031519	PcG protein complex
0.41	GO:0016580	Sin3 complex
0.41	GO:0090545	CHD-type complex
0.40	GO:0090568	nuclear transcriptional repressor complex
0.40	GO:0005956	protein kinase CK2 complex
0.34	GO:0005886	plasma membrane
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.68

GO:0004674

sp|P21869|CSK22_CHICK
Casein kinase II subunit alpha'
Search

CSNK2A2

0.80	Casein kinase II subunit alpha'

0.63	GO:0006468	protein phosphorylation
0.56	GO:1903146	regulation of autophagy of mitochondrion
0.55	GO:1903955	positive regulation of protein targeting to mitochondrion
0.53	GO:1905818	regulation of chromosome separation
0.40	GO:0097421	liver regeneration
0.39	GO:0021987	cerebral cortex development
0.38	GO:0007283	spermatogenesis
0.38	GO:0016055	Wnt signaling pathway
0.37	GO:0006915	apoptotic process
0.35	GO:0007049	cell cycle

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0047485	protein N-terminus binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0031519	PcG protein complex
0.39	GO:0001669	acrosomal vesicle
0.37	GO:0000785	chromatin
0.35	GO:0005956	protein kinase CK2 complex
0.34	GO:0005886	plasma membrane
0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol

0.68

GO:0004674

sp|P21872|PUR2_CHICK
Trifunctional purine biosynthetic protein adenosine-3
Search

GART

0.91	Trifunctional purine biosynthetic protein adenosine-3

0.72	GO:0009113	purine nucleobase biosynthetic process
0.68	GO:0006189	'de novo' IMP biosynthetic process
0.40	GO:0048513	animal organ development
0.40	GO:0043473	pigmentation
0.39	GO:0043009	chordate embryonic development
0.39	GO:0003360	brainstem development
0.37	GO:0060322	head development
0.37	GO:0007417	central nervous system development
0.36	GO:0046654	tetrahydrofolate biosynthetic process
0.36	GO:0006544	glycine metabolic process

0.76	GO:0004641	phosphoribosylformylglycinamidine cyclo-ligase activity
0.76	GO:0004637	phosphoribosylamine-glycine ligase activity
0.75	GO:0004644	phosphoribosylglycinamide formyltransferase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding

0.47	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.76	EC:6.3.3.1	GO:0004641
0.76	KEGG:R04208	GO:0004641

sp|P22328|OPSD_CHICK
Rhodopsin
Search

RH1

0.55

Rhodopsin

0.79	GO:0007602	phototransduction
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.68	GO:0007601	visual perception
0.65	GO:0018298	protein-chromophore linkage
0.54	GO:0016037	light absorption
0.53	GO:0070207	protein homotrimerization
0.44	GO:0071482	cellular response to light stimulus
0.43	GO:0045494	photoreceptor cell maintenance
0.42	GO:0060041	retina development in camera-type eye
0.38	GO:0006468	protein phosphorylation

0.72	GO:0004930	G-protein coupled receptor activity
0.68	GO:0009881	photoreceptor activity
0.48	GO:0042803	protein homodimerization activity
0.39	GO:0005502	11-cis retinal binding
0.37	GO:0001965	G-protein alpha-subunit binding
0.32	GO:0046872	metal ion binding

0.54	GO:0001750	photoreceptor outer segment
0.46	GO:0060342	photoreceptor inner segment membrane
0.45	GO:0060170	ciliary membrane
0.41	GO:0005911	cell-cell junction
0.40	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

sp|P22329|OPSR_CHICK
Red-sensitive opsin
Search

OPN1LW

0.76	Long wavelength sensitive visual pigment

0.79	GO:0007602	phototransduction
0.78	GO:0007601	visual perception
0.75	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.43	GO:0016038	absorption of visible light
0.42	GO:0009584	detection of visible light
0.42	GO:0016039	absorption of UV light
0.41	GO:0070207	protein homotrimerization
0.36	GO:0001523	retinoid metabolic process
0.36	GO:0032467	positive regulation of cytokinesis

0.79	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.41	GO:0031404	chloride ion binding
0.40	GO:0042802	identical protein binding
0.37	GO:0046983	protein dimerization activity

0.52	GO:0001750	photoreceptor outer segment
0.42	GO:0060342	photoreceptor inner segment membrane
0.40	GO:0044297	cell body
0.38	GO:0031982	vesicle
0.38	GO:0005794	Golgi apparatus
0.36	GO:0060170	ciliary membrane
0.34	GO:0005887	integral component of plasma membrane

sp|P22448|RARB_CHICK
Retinoic acid receptor beta
Search

RARB

0.90	Retinoic acid receptor alpha

0.85	GO:0048384	retinoic acid receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0003417	growth plate cartilage development
0.57	GO:0055012	ventricular cardiac muscle cell differentiation
0.57	GO:0061037	negative regulation of cartilage development
0.56	GO:0003148	outflow tract septum morphogenesis
0.56	GO:0002068	glandular epithelial cell development
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.85	GO:0003708	retinoic acid receptor activity
0.79	GO:0003707	steroid hormone receptor activity
0.62	GO:0043565	sequence-specific DNA binding
0.61	GO:0008270	zinc ion binding
0.52	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003690	double-stranded DNA binding
0.40	GO:0046965	retinoid X receptor binding
0.40	GO:0043422	protein kinase B binding
0.39	GO:0001972	retinoic acid binding
0.39	GO:0051393	alpha-actinin binding

0.61	GO:0005634	nucleus
0.48	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.38	GO:0043025	neuronal cell body
0.38	GO:0030425	dendrite
0.38	GO:0015629	actin cytoskeleton
0.37	GO:0005829	cytosol
0.36	GO:0005694	chromosome
0.36	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0009986	cell surface

sp|P22451|RL5_CHICK
60S ribosomal protein L5
Search

RPL5

0.61	Ribosomal protein L5

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.48	GO:0000027	ribosomal large subunit assembly
0.47	GO:2000435	negative regulation of protein neddylation
0.46	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.46	GO:1904667	negative regulation of ubiquitin protein ligase activity
0.45	GO:1901796	regulation of signal transduction by p53 class mediator
0.43	GO:0050821	protein stabilization

0.79	GO:0008097	5S rRNA binding
0.64	GO:0003735	structural constituent of ribosome
0.47	GO:1990948	ubiquitin ligase inhibitor activity
0.44	GO:0003730	mRNA 3'-UTR binding
0.44	GO:0048027	mRNA 5'-UTR binding
0.43	GO:0031625	ubiquitin protein ligase binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.45	GO:0005829	cytosol
0.44	GO:0005730	nucleolus
0.41	GO:0005783	endoplasmic reticulum
0.41	GO:0005654	nucleoplasm
0.38	GO:0043234	protein complex
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.32

GO:0016787

sp|P22728|VISI_CHICK
Visinin
Search

RCVRN

0.97	Recoverin a

0.59	GO:0036368	cone photoresponse recovery
0.52	GO:0051924	regulation of calcium ion transport
0.52	GO:0007601	visual perception
0.51	GO:0007602	phototransduction
0.35	GO:0031284	positive regulation of guanylate cyclase activity

0.70	GO:0005509	calcium ion binding
0.35	GO:0008048	calcium sensitive guanylate cyclase activator activity
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0030425	dendrite
0.34	GO:0005829	cytosol

sp|P22770|ACHA7_CHICK
Neuronal acetylcholine receptor subunit alpha-7
Search

CHRNA7

0.89	LOW QUALITY PROTEIN: neuronal acetylcholine receptor subunit alpha-7

0.77	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.51	GO:0035094	response to nicotine
0.48	GO:1905920	positive regulation of CoA-transferase activity
0.48	GO:0001988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure
0.48	GO:0050893	sensory processing
0.48	GO:0032720	negative regulation of tumor necrosis factor production
0.47	GO:0060112	generation of ovulation cycle rhythm
0.47	GO:0140059	dendrite arborization
0.47	GO:1905906	regulation of amyloid fibril formation

0.80	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.42	GO:0017081	chloride channel regulator activity
0.42	GO:0042166	acetylcholine binding
0.41	GO:0001540	amyloid-beta binding
0.41	GO:0015643	toxic substance binding
0.39	GO:0042803	protein homodimerization activity
0.35	GO:0008179	adenylate cyclase binding
0.35	GO:0097110	scaffold protein binding
0.35	GO:0051117	ATPase binding

0.76	GO:0045211	postsynaptic membrane
0.72	GO:0030054	cell junction
0.56	GO:0030424	axon
0.56	GO:0043204	perikaryon
0.54	GO:0120038	plasma membrane bounded cell projection part
0.54	GO:0097447	dendritic tree
0.46	GO:0005892	acetylcholine-gated channel complex
0.44	GO:0031256	leading edge membrane
0.43	GO:0009897	external side of plasma membrane
0.43	GO:0016324	apical plasma membrane

sp|P23007|CISY_CHICK
Citrate synthase, mitochondrial
Search

0.45	Citrate synthase, mitochondrial

0.70	GO:0006101	citrate metabolic process
0.63	GO:0009060	aerobic respiration
0.45	GO:0005975	carbohydrate metabolic process
0.35	GO:0014823	response to activity
0.34	GO:0006107	oxaloacetate metabolic process
0.34	GO:0006084	acetyl-CoA metabolic process

0.76	GO:0004108	citrate (Si)-synthase activity
0.34	GO:0003723	RNA binding

0.52	GO:0005759	mitochondrial matrix
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus

0.76

EC:2.3.3.1

GO:0004108

sp|P23068|HB2L_CHICK
Class II histocompatibility antigen, B-L beta chain (Fragment)
Search

0.43	MHC class II antigen beta chain

0.76	GO:0019882	antigen processing and presentation
0.73	GO:0006955	immune response

0.75	GO:0042613	MHC class II protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P23228|HMCS1_CHICK
Hydroxymethylglutaryl-CoA synthase, cytoplasmic
Search

HMGCS1

0.67	3-hydroxy-3-methylglutaryl coenzyme A synthase

0.79	GO:0016126	sterol biosynthetic process
0.71	GO:0008299	isoprenoid biosynthetic process
0.46	GO:0014003	oligodendrocyte development
0.35	GO:0033197	response to vitamin E
0.35	GO:0071372	cellular response to follicle-stimulating hormone stimulus
0.35	GO:0071397	cellular response to cholesterol
0.35	GO:0009645	response to low light intensity stimulus
0.35	GO:0071404	cellular response to low-density lipoprotein particle stimulus
0.35	GO:0046690	response to tellurium ion
0.34	GO:0008584	male gonad development

0.83	GO:0004421	hydroxymethylglutaryl-CoA synthase activity
0.34	GO:0008009	chemokine activity
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0043177	organic acid binding
0.33	GO:0016853	isomerase activity
0.32	GO:0008144	drug binding

0.33	GO:0005829	cytosol
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.83	EC:2.3.3.10	GO:0004421
0.83	KEGG:R01978	GO:0004421

sp|P23289|MYPR_CHICK
Myelin proteolipid protein
Search

PLP1

0.93	Myelin proteolipid protein B

0.62	GO:0022010	central nervous system myelination
0.62	GO:0014002	astrocyte development
0.61	GO:0042759	long-chain fatty acid biosynthetic process
0.58	GO:0048469	cell maturation
0.57	GO:0006954	inflammatory response
0.57	GO:0061564	axon development
0.53	GO:0010628	positive regulation of gene expression
0.41	GO:0007229	integrin-mediated signaling pathway
0.39	GO:0021762	substantia nigra development
0.35	GO:0007268	chemical synaptic transmission

0.43	GO:0019911	structural constituent of myelin sheath
0.38	GO:0042802	identical protein binding

0.60	GO:0043209	myelin sheath
0.45	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P23459|HXD8_CHICK
Homeobox protein Hox-D8
Search

0.96	Homeobox protein Hox-beta8

0.68	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0007625	grooming behavior
0.52	GO:0019233	sensory perception of pain
0.51	GO:0045638	negative regulation of myeloid cell differentiation
0.51	GO:0008344	adult locomotory behavior
0.51	GO:0009653	anatomical structure morphogenesis
0.51	GO:1902679	negative regulation of RNA biosynthetic process

0.65	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.45	GO:0043233	organelle lumen
0.41	GO:0044446	intracellular organelle part

sp|P23498|OSTP_CHICK
Osteopontin
Search

SPP1

0.97	Osteopontin

0.83	GO:0001503	ossification
0.72	GO:0007155	cell adhesion
0.44	GO:0031214	biomineral tissue development
0.44	GO:0046852	positive regulation of bone remodeling
0.43	GO:0045124	regulation of bone resorption
0.42	GO:0032846	positive regulation of homeostatic process
0.41	GO:0010646	regulation of cell communication
0.41	GO:0023051	regulation of signaling
0.40	GO:0030154	cell differentiation
0.39	GO:0048583	regulation of response to stimulus

0.49	GO:0008201	heparin binding
0.42	GO:0005125	cytokine activity
0.42	GO:0050840	extracellular matrix binding

0.42	GO:0005615	extracellular space
0.39	GO:0031012	extracellular matrix
0.36	GO:0005794	Golgi apparatus

sp|P23614|BASP1_CHICK
Brain acid soluble protein 1 homolog
Search

BASP1

0.97	Brain abundant membrane attached signal protein 1

0.78	GO:0072112	glomerular visceral epithelial cell differentiation
0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.47	GO:0021762	substantia nigra development
0.44	GO:2001076	positive regulation of metanephric ureteric bud development
0.44	GO:0007356	thorax and anterior abdomen determination
0.43	GO:0060539	diaphragm development
0.43	GO:0072075	metanephric mesenchyme development
0.43	GO:0060231	mesenchymal to epithelial transition
0.42	GO:0060421	positive regulation of heart growth
0.41	GO:0008406	gonad development

0.78	GO:0003714	transcription corepressor activity
0.73	GO:0019904	protein domain specific binding
0.69	GO:0044212	transcription regulatory region DNA binding
0.38	GO:0005516	calmodulin binding

0.77	GO:0008180	COP9 signalosome
0.72	GO:0016607	nuclear speck
0.70	GO:0030054	cell junction
0.55	GO:0030426	growth cone
0.55	GO:0005886	plasma membrane
0.48	GO:0005737	cytoplasm
0.44	GO:0070062	extracellular exosome
0.43	GO:0005856	cytoskeleton
0.43	GO:0098562	cytoplasmic side of membrane
0.42	GO:0019898	extrinsic component of membrane

sp|P23668|LEG6_CHICK
16 kDa beta-galactoside-binding lectin
Search

0.69

Galectin

0.42	GO:0002317	plasma cell differentiation
0.41	GO:0046598	positive regulation of viral entry into host cell
0.41	GO:0031295	T cell costimulation
0.41	GO:0045445	myoblast differentiation

0.70

GO:0030246

carbohydrate binding

0.38	GO:0031012	extracellular matrix
0.38	GO:0005615	extracellular space
0.33	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

sp|P23681|HXB8_CHICK
Homeobox protein Hox-B8 (Fragment)
Search

0.84	Homeobox protein Hox-B8 (Fragment)

0.68	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0007625	grooming behavior
0.53	GO:0009653	anatomical structure morphogenesis
0.52	GO:0019233	sensory perception of pain
0.52	GO:0045638	negative regulation of myeloid cell differentiation
0.52	GO:1902679	negative regulation of RNA biosynthetic process
0.51	GO:0008344	adult locomotory behavior

0.64	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.45	GO:0015630	microtubule cytoskeleton

sp|P23682|HXB3_CHICK
Homeobox protein Hox-B3
Search

HOXB3

0.95	Transcription factor HoxB3

0.68	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0061448	connective tissue development
0.46	GO:0051960	regulation of nervous system development
0.46	GO:0060284	regulation of cell development
0.44	GO:1902680	positive regulation of RNA biosynthetic process
0.44	GO:0009653	anatomical structure morphogenesis
0.44	GO:0007219	Notch signaling pathway

0.63	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding
0.37	GO:0071837	HMG box domain binding

0.61	GO:0005634	nucleus
0.45	GO:0016235	aggresome
0.41	GO:0043233	organelle lumen
0.38	GO:0044446	intracellular organelle part

sp|P23824|GATA2_CHICK
GATA-binding factor 2
Search

GATA2

0.37	Endothelial transcription factor GATA-2

0.72	GO:0030097	hemopoiesis
0.59	GO:1903708	positive regulation of hemopoiesis
0.58	GO:1902105	regulation of leukocyte differentiation
0.58	GO:0021514	ventral spinal cord interneuron differentiation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2000352	negative regulation of endothelial cell apoptotic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0045599	negative regulation of fat cell differentiation
0.56	GO:0045597	positive regulation of cell differentiation

0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.57	GO:0044212	transcription regulatory region DNA binding
0.55	GO:0070742	C2H2 zinc finger domain binding
0.55	GO:0003690	double-stranded DNA binding
0.53	GO:0003682	chromatin binding
0.52	GO:0008134	transcription factor binding
0.43	GO:0071837	HMG box domain binding
0.42	GO:0005134	interleukin-2 receptor binding

0.57	GO:0005634	nucleus
0.47	GO:0070013	intracellular organelle lumen
0.47	GO:0005667	transcription factor complex
0.43	GO:0044446	intracellular organelle part
0.38	GO:0005694	chromosome

sp|P23825|GATA3_CHICK
GATA-binding factor 3
Search

GATA3

0.96	Trans-acting T-cell-specific transcription factor GATA-3

0.84	GO:0045582	positive regulation of T cell differentiation
0.60	GO:2000611	positive regulation of thyroid hormone generation
0.60	GO:2000667	positive regulation of interleukin-13 secretion
0.60	GO:2000683	regulation of cellular response to X-ray
0.60	GO:2000664	positive regulation of interleukin-5 secretion
0.59	GO:0033600	negative regulation of mammary gland epithelial cell proliferation
0.59	GO:0060231	mesenchymal to epithelial transition
0.58	GO:0035457	cellular response to interferon-alpha
0.58	GO:2000702	regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
0.58	GO:2000733	regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation

0.75	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0071837	HMG box domain binding
0.55	GO:0005134	interleukin-2 receptor binding
0.55	GO:0001047	core promoter binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0003713	transcription coactivator activity
0.53	GO:0035326	enhancer binding
0.52	GO:0008134	transcription factor binding

0.60	GO:0005634	nucleus
0.50	GO:0000785	chromatin
0.48	GO:0070013	intracellular organelle lumen
0.45	GO:0005667	transcription factor complex
0.30	GO:0016021	integral component of membrane

sp|P23913|LBR_CHICK
Lamin-B receptor
Search

LBR

0.95	Lamin-B receptor

0.53	GO:0055114	oxidation-reduction process
0.47	GO:0016126	sterol biosynthetic process
0.38	GO:0042074	cell migration involved in gastrulation
0.36	GO:1902653	secondary alcohol biosynthetic process
0.36	GO:0008203	cholesterol metabolic process
0.34	GO:0045540	regulation of cholesterol biosynthetic process
0.34	GO:0000278	mitotic cell cycle
0.33	GO:0008204	ergosterol metabolic process
0.33	GO:0044108	cellular alcohol biosynthetic process
0.33	GO:0016129	phytosteroid biosynthetic process

0.73	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
0.60	GO:0070087	chromo shadow domain binding
0.35	GO:0005521	lamin binding
0.35	GO:0003677	DNA binding
0.35	GO:0008139	nuclear localization sequence binding
0.34	GO:0051087	chaperone binding
0.34	GO:0003723	RNA binding
0.33	GO:0050661	NADP binding
0.32	GO:0003735	structural constituent of ribosome

0.57	GO:0031965	nuclear membrane
0.47	GO:0005783	endoplasmic reticulum
0.45	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.44	GO:0031301	integral component of organelle membrane
0.43	GO:0031984	organelle subcompartment
0.42	GO:0019866	organelle inner membrane
0.42	GO:0043235	receptor complex
0.35	GO:0005652	nuclear lamina
0.34	GO:0005643	nuclear pore
0.33	GO:0005887	integral component of plasma membrane

0.73

EC:1.3.1

GO:0016628

sp|P23991|ADH1_CHICK
Alcohol dehydrogenase 1
Search

0.73	Alcohol dehydrogenase class I

0.51	GO:0055114	oxidation-reduction process
0.45	GO:0006067	ethanol metabolic process
0.42	GO:0042573	retinoic acid metabolic process
0.41	GO:0042572	retinol metabolic process
0.41	GO:0045471	response to ethanol
0.41	GO:0034310	primary alcohol catabolic process
0.40	GO:0033574	response to testosterone
0.39	GO:0032526	response to retinoic acid
0.39	GO:0030534	adult behavior
0.38	GO:0042737	drug catabolic process

0.61	GO:0008270	zinc ion binding
0.55	GO:0004022	alcohol dehydrogenase (NAD) activity
0.41	GO:0004745	retinol dehydrogenase activity
0.39	GO:0035276	ethanol binding
0.38	GO:0042803	protein homodimerization activity
0.37	GO:0004031	aldehyde oxidase activity
0.37	GO:0019841	retinol binding
0.37	GO:0048019	receptor antagonist activity
0.35	GO:0051287	NAD binding
0.35	GO:0051903	S-(hydroxymethyl)glutathione dehydrogenase activity

0.42	GO:0005829	cytosol
0.41	GO:0005654	nucleoplasm
0.38	GO:0005886	plasma membrane
0.35	GO:0005739	mitochondrion
0.34	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.55	EC:1.1.1.1	GO:0004022
0.35	KEGG:R06983 KEGG:R07140	GO:0051903

sp|P24032|MLRN_CHICK
Myosin regulatory light chain 2, smooth muscle minor isoform
Search

0.88	Myosin regulatory light chain

0.48	GO:0008360	regulation of cell shape
0.44	GO:0072659	protein localization to plasma membrane
0.36	GO:0006936	muscle contraction
0.35	GO:0070527	platelet aggregation
0.34	GO:0048013	ephrin receptor signaling pathway
0.34	GO:0031032	actomyosin structure organization

0.68	GO:0005509	calcium ion binding
0.53	GO:0032036	myosin heavy chain binding
0.46	GO:0035254	glutamate receptor binding
0.35	GO:0030898	actin-dependent ATPase activity
0.34	GO:0051015	actin filament binding
0.34	GO:0051020	GTPase binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0016460	myosin II complex
0.55	GO:0097517	contractile actin filament bundle
0.55	GO:0042641	actomyosin
0.55	GO:0030018	Z disc
0.50	GO:0005903	brush border
0.50	GO:0099738	cell cortex region
0.48	GO:0045177	apical part of cell
0.37	GO:0070062	extracellular exosome
0.35	GO:0097513	myosin II filament
0.34	GO:0005829	cytosol

sp|P24045|GBRB4_CHICK
Gamma-aminobutyric acid receptor subunit beta-4
Search

0.86	Gamma-aminobutyric acid receptor subunit beta-4

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.45	GO:0060384	innervation
0.45	GO:0090102	cochlea development
0.44	GO:0060119	inner ear receptor cell development
0.44	GO:0043524	negative regulation of neuron apoptotic process
0.43	GO:0007605	sensory perception of sound
0.40	GO:0006821	chloride transport
0.39	GO:0071420	cellular response to histamine
0.36	GO:0060021	palate development

0.84	GO:0004890	GABA-A receptor activity
0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.40	GO:0005254	chloride channel activity
0.38	GO:0099095	ligand-gated anion channel activity
0.37	GO:0022835	transmitter-gated channel activity
0.35	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.44	GO:1902711	GABA-A receptor complex
0.39	GO:0098794	postsynapse
0.38	GO:0034707	chloride channel complex
0.37	GO:0030054	cell junction
0.35	GO:0030659	cytoplasmic vesicle membrane

sp|P24052|MK_CHICK
Midkine
Search

MDK

0.97	Pleiotrophic factor-alpha-2

0.76	GO:0010469	regulation of receptor activity
0.52	GO:0030421	defecation
0.52	GO:0021681	cerebellar granular layer development
0.52	GO:0021542	dentate gyrus development
0.52	GO:0007614	short-term memory
0.51	GO:0001662	behavioral fear response
0.50	GO:0021987	cerebral cortex development
0.50	GO:0043524	negative regulation of neuron apoptotic process
0.50	GO:0050795	regulation of behavior
0.49	GO:0009611	response to wounding

0.78	GO:0008083	growth factor activity
0.53	GO:0008201	heparin binding
0.42	GO:0035374	chondroitin sulfate binding
0.38	GO:0019901	protein kinase binding
0.37	GO:0043395	heparan sulfate proteoglycan binding

0.42	GO:0005576	extracellular region
0.37	GO:0012505	endomembrane system
0.35	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0042995	cell projection
0.35	GO:0043234	protein complex
0.35	GO:0044444	cytoplasmic part
0.34	GO:0009986	cell surface
0.30	GO:0016020	membrane

sp|P24271|RAG1_CHICK
V(D)J recombination-activating protein 1
Search

RAG-1

0.56	V(D)J recombination-activating protein 1

0.78	GO:0033151	V(D)J recombination
0.73	GO:0016567	protein ubiquitination
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.49	GO:0033077	T cell differentiation in thymus
0.49	GO:0030183	B cell differentiation
0.45	GO:0016570	histone modification

0.76	GO:0061630	ubiquitin protein ligase activity
0.75	GO:0042803	protein homodimerization activity
0.66	GO:0004519	endonuclease activity
0.65	GO:0043565	sequence-specific DNA binding
0.54	GO:0046872	metal ion binding
0.47	GO:0042393	histone binding

0.61

GO:0005634

nucleus

sp|P24340|HXD9_CHICK
Homeobox protein Hox-D9 (Fragment)
Search

0.65	Homeobox protein Hox-D9

0.62	GO:0007275	multicellular organism development
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0006351	transcription, DNA-templated
0.50	GO:1902680	positive regulation of RNA biosynthetic process
0.50	GO:0008344	adult locomotory behavior
0.49	GO:0007338	single fertilization
0.49	GO:0014706	striated muscle tissue development
0.48	GO:0061061	muscle structure development

0.64	GO:0043565	sequence-specific DNA binding
0.52	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003690	double-stranded DNA binding
0.49	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.34	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0005667	transcription factor complex
0.42	GO:0044446	intracellular organelle part
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0005739	mitochondrion

sp|P24341|HXD10_CHICK
Homeobox protein Hox-D10 (Fragment)
Search

0.57	Homeobox transcription factor (Fragment)

0.57	GO:0021520	spinal cord motor neuron cell fate specification
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0009954	proximal/distal pattern formation
0.55	GO:0050905	neuromuscular process
0.55	GO:0030326	embryonic limb morphogenesis
0.54	GO:0048935	peripheral nervous system neuron development
0.54	GO:0035137	hindlimb morphogenesis
0.54	GO:0035136	forelimb morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.53	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.52	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003682	chromatin binding
0.49	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.50	GO:0036464	cytoplasmic ribonucleoprotein granule
0.47	GO:0031974	membrane-enclosed lumen
0.46	GO:0005829	cytosol
0.43	GO:0044446	intracellular organelle part
0.41	GO:0150005	enzyme activator complex
0.40	GO:0000307	cyclin-dependent protein kinase holoenzyme complex

sp|P24342|HXD11_CHICK
Homeobox protein Hox-D11
Search

0.88	Homeobox transcription factor

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.39	GO:0007275	multicellular organism development
0.37	GO:0006351	transcription, DNA-templated
0.32	GO:0032332	positive regulation of chondrocyte differentiation
0.32	GO:0001759	organ induction
0.32	GO:0061138	morphogenesis of a branching epithelium
0.32	GO:0007338	single fertilization
0.32	GO:0061448	connective tissue development

0.64	GO:0043565	sequence-specific DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.41	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part

sp|P24343|HXD12_CHICK
Homeobox protein Hox-D12
Search

HOXD12

0.96	Homeobox protein Hox-D12

0.59	GO:0042733	embryonic digit morphogenesis
0.56	GO:0001501	skeletal system development
0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0007389	pattern specification process
0.54	GO:0010468	regulation of gene expression
0.37	GO:0006351	transcription, DNA-templated

0.62	GO:0043565	sequence-specific DNA binding
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.53	GO:0005667	transcription factor complex

sp|P24344|HXD13_CHICK
Homeobox protein Hox-D13
Search

HOXD13

0.94	Transcription factor HoxD13

0.57	GO:0060526	prostate glandular acinus morphogenesis
0.57	GO:0060687	regulation of branching involved in prostate gland morphogenesis
0.56	GO:0060442	branching involved in prostate gland morphogenesis
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0060602	branch elongation of an epithelium
0.56	GO:0010468	regulation of gene expression
0.55	GO:0060571	morphogenesis of an epithelial fold
0.55	GO:0030539	male genitalia development
0.54	GO:0042733	embryonic digit morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.54	GO:0035326	enhancer binding
0.53	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.52	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003682	chromatin binding
0.48	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P24367|PPIB_CHICK
Peptidyl-prolyl cis-trans isomerase B
Search

PPIB

0.48	Peptidyl-prolyl cis-trans isomerase B

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.68	GO:0006457	protein folding
0.56	GO:0044829	positive regulation by host of viral genome replication
0.54	GO:0040018	positive regulation of multicellular organism growth
0.52	GO:0060348	bone development
0.51	GO:0050821	protein stabilization
0.37	GO:1901873	regulation of post-translational protein modification
0.34	GO:0051169	nuclear transport

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.50	GO:0070063	RNA polymerase binding
0.48	GO:0032403	protein complex binding
0.39	GO:0016018	cyclosporin A binding
0.33	GO:0051082	unfolded protein binding
0.33	GO:0003723	RNA binding
0.32	GO:0046872	metal ion binding

0.54	GO:0034663	endoplasmic reticulum chaperone complex
0.50	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0005634	nucleus
0.40	GO:0042470	melanosome
0.39	GO:0005788	endoplasmic reticulum lumen
0.39	GO:0005790	smooth endoplasmic reticulum
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.72

EC:5.2.1.8

GO:0003755

sp|P24479|S10AB_CHICK
Protein S100-A11
Search

0.76	GO:0042127	regulation of cell proliferation
0.48	GO:0098609	cell-cell adhesion
0.36	GO:0007283	spermatogenesis
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0008156	negative regulation of DNA replication
0.34	GO:0051013	microtubule severing
0.33	GO:0051301	cell division
0.33	GO:0007049	cell cycle
0.33	GO:0007165	signal transduction

0.85	GO:0048306	calcium-dependent protein binding
0.70	GO:0005509	calcium ion binding
0.53	GO:0098641	cadherin binding involved in cell-cell adhesion
0.52	GO:0044548	S100 protein binding
0.47	GO:0042803	protein homodimerization activity
0.35	GO:0008568	microtubule-severing ATPase activity
0.34	GO:0046914	transition metal ion binding
0.34	GO:0008017	microtubule binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.51	GO:0005913	cell-cell adherens junction
0.50	GO:0001726	ruffle
0.44	GO:0005576	extracellular region
0.42	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.35	GO:0031982	vesicle
0.34	GO:0030496	midbody
0.34	GO:0000922	spindle pole
0.34	GO:0005813	centrosome
0.34	GO:0005874	microtubule

0.35

EC:3.6.4.3

GO:0008568

sp|P24503|CADH4_CHICK
Cadherin-4
Search

CDH4

0.96	Cadherin 4, type 1, R-cadherin (retinal)

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.54	GO:0045773	positive regulation of axon extension
0.54	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.51	GO:0007411	axon guidance
0.39	GO:0042478	regulation of eye photoreceptor cell development
0.39	GO:0048925	lateral line system development
0.38	GO:0021545	cranial nerve development
0.38	GO:0060042	retina morphogenesis in camera-type eye
0.36	GO:0009966	regulation of signal transduction
0.35	GO:1902897	regulation of postsynaptic density protein 95 clustering

0.70	GO:0005509	calcium ion binding
0.35	GO:0045295	gamma-catenin binding
0.35	GO:0045294	alpha-catenin binding
0.34	GO:0019903	protein phosphatase binding
0.34	GO:0008013	beta-catenin binding
0.34	GO:0019901	protein kinase binding
0.34	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.35	GO:0005916	fascia adherens
0.34	GO:0014069	postsynaptic density
0.34	GO:0030027	lamellipodium
0.34	GO:0030864	cortical actin cytoskeleton
0.34	GO:0045121	membrane raft
0.34	GO:0045177	apical part of cell
0.34	GO:0009986	cell surface
0.34	GO:0019898	extrinsic component of membrane
0.34	GO:0031012	extracellular matrix

sp|P24787|NEUV_CHICK
Vasotocin-neurophysin VT
Search

AVP

0.96	Arginine vasotocin preprohormone

0.76	GO:0010469	regulation of receptor activity
0.48	GO:0070528	protein kinase C signaling
0.48	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.47	GO:0070371	ERK1 and ERK2 cascade
0.46	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.46	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.44	GO:0006915	apoptotic process
0.42	GO:0010628	positive regulation of gene expression
0.40	GO:0002125	maternal aggressive behavior
0.40	GO:0008015	blood circulation

0.86	GO:0005185	neurohypophyseal hormone activity
0.50	GO:0031894	V1A vasopressin receptor binding
0.47	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.40	GO:0004871	signal transducer activity
0.40	GO:0004672	protein kinase activity
0.39	GO:0031895	V1B vasopressin receptor binding
0.37	GO:0031855	oxytocin receptor binding
0.35	GO:0031896	V2 vasopressin receptor binding
0.34	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0052795	exo-alpha-(2->6)-sialidase activity

0.66	GO:0005576	extracellular region
0.43	GO:0043203	axon hillock
0.38	GO:0030141	secretory granule
0.37	GO:0030425	dendrite
0.36	GO:0043195	terminal bouton
0.34	GO:0030665	clathrin-coated vesicle membrane
0.33	GO:0005829	cytosol
0.30	GO:0044425	membrane part

0.34	EC:3.2.1.18	GO:0052795
0.34	KEGG:R03876	GO:0004842

sp|P24797|AT1A2_CHICK
Sodium/potassium-transporting ATPase subunit alpha-2
Search

ATP1A2

0.64	Sodium/potassium-transporting ATPase subunit alpha

0.84	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.75	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.72	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.60	GO:0006883	cellular sodium ion homeostasis
0.58	GO:0008542	visual learning
0.57	GO:0030007	cellular potassium ion homeostasis
0.57	GO:0008344	adult locomotory behavior
0.57	GO:0140115	export across plasma membrane
0.56	GO:0008015	blood circulation

0.84	GO:0005391	sodium:potassium-exchanging ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:1990239	steroid hormone binding
0.53	GO:0046872	metal ion binding
0.53	GO:0051087	chaperone binding
0.48	GO:0001540	amyloid-beta binding
0.44	GO:1901681	sulfur compound binding

0.57	GO:0005890	sodium:potassium-exchanging ATPase complex
0.57	GO:0042383	sarcolemma
0.56	GO:0043209	myelin sheath
0.48	GO:0036477	somatodendritic compartment
0.48	GO:0043005	neuron projection
0.47	GO:0044297	cell body
0.44	GO:0012505	endomembrane system
0.42	GO:0098794	postsynapse
0.41	GO:0005634	nucleus
0.40	GO:0098590	plasma membrane region

0.84

GO:0005391

sp|P24798|AT1A3_CHICK
Sodium/potassium-transporting ATPase subunit alpha-3
Search

ATP1A3

0.64	Sodium/potassium-transporting ATPase subunit alpha

0.85	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.76	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.58	GO:0006883	cellular sodium ion homeostasis
0.57	GO:0007626	locomotory behavior
0.56	GO:0008542	visual learning
0.55	GO:0030007	cellular potassium ion homeostasis
0.55	GO:0140115	export across plasma membrane
0.54	GO:0030534	adult behavior

0.85	GO:0005391	sodium:potassium-exchanging ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0046872	metal ion binding
0.51	GO:0051087	chaperone binding
0.49	GO:1990239	steroid hormone binding
0.49	GO:0001540	amyloid-beta binding
0.44	GO:1901681	sulfur compound binding

0.55	GO:0005890	sodium:potassium-exchanging ATPase complex
0.55	GO:0042383	sarcolemma
0.54	GO:0043209	myelin sheath
0.48	GO:0036477	somatodendritic compartment
0.47	GO:0043005	neuron projection
0.47	GO:0044297	cell body
0.44	GO:0005794	Golgi apparatus
0.44	GO:0005783	endoplasmic reticulum
0.42	GO:0098794	postsynapse
0.41	GO:0005634	nucleus

0.85

GO:0005391

sp|P24802|PLOD1_CHICK
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
Search

PLOD1

0.97	Lysyl hydroxylase

0.59	GO:0017185	peptidyl-lysine hydroxylation
0.59	GO:0046947	hydroxylysine biosynthetic process
0.53	GO:0008544	epidermis development
0.52	GO:0055114	oxidation-reduction process
0.52	GO:0001666	response to hypoxia
0.44	GO:0033334	fin morphogenesis
0.41	GO:0006493	protein O-linked glycosylation
0.40	GO:0001886	endothelial cell morphogenesis
0.40	GO:0070831	basement membrane assembly
0.40	GO:0042311	vasodilation

0.86	GO:0008475	procollagen-lysine 5-dioxygenase activity
0.78	GO:0031418	L-ascorbic acid binding
0.62	GO:0005506	iron ion binding
0.44	GO:0033823	procollagen glucosyltransferase activity
0.34	GO:0042277	peptide binding
0.34	GO:0005515	protein binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.70	GO:0005783	endoplasmic reticulum
0.43	GO:1902494	catalytic complex
0.40	GO:0031984	organelle subcompartment
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0005581	collagen trimer
0.39	GO:0098588	bounding membrane of organelle
0.39	GO:0044421	extracellular region part
0.37	GO:0044431	Golgi apparatus part
0.36	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:1.14.11.4

GO:0008475

sp|P24899|TAL1_CHICK
T-cell acute lymphocytic leukemia protein 1 homolog
Search

TAL1

0.94	Stem cell leukemia protein SCL

0.60	GO:0060217	hemangioblast cell differentiation
0.59	GO:0060375	regulation of mast cell differentiation
0.58	GO:0060018	astrocyte fate commitment
0.58	GO:0030221	basophil differentiation
0.57	GO:0060216	definitive hemopoiesis
0.57	GO:0060218	hematopoietic stem cell differentiation
0.57	GO:0043249	erythrocyte maturation
0.57	GO:0021527	spinal cord association neuron differentiation
0.56	GO:0035855	megakaryocyte development
0.56	GO:0030220	platelet formation

0.68	GO:0046983	protein dimerization activity
0.56	GO:0070888	E-box binding
0.55	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.54	GO:0042826	histone deacetylase binding
0.53	GO:0001085	RNA polymerase II transcription factor binding
0.52	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.51	GO:0003682	chromatin binding

0.58	GO:0033193	Lsd1/2 complex
0.53	GO:0000118	histone deacetylase complex
0.50	GO:0005667	transcription factor complex
0.50	GO:0000790	nuclear chromatin
0.30	GO:0016021	integral component of membrane

sp|P25022|RAG2_CHICK
V(D)J recombination-activating protein 2
Search

RAG2

0.52	Recombination activating 2

0.65	GO:0006310	DNA recombination
0.40	GO:0033077	T cell differentiation in thymus
0.39	GO:0002358	B cell homeostatic proliferation
0.39	GO:0030183	B cell differentiation
0.39	GO:0002360	T cell lineage commitment
0.38	GO:0046622	positive regulation of organ growth
0.38	GO:0002200	somatic diversification of immune receptors
0.37	GO:0042742	defense response to bacterium
0.36	GO:0016567	protein ubiquitination
0.34	GO:0016569	covalent chromatin modification

0.55	GO:0003677	DNA binding
0.40	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.40	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.40	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.39	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.39	GO:0140034	methylation-dependent protein binding
0.39	GO:0042393	histone binding
0.38	GO:0003682	chromatin binding
0.37	GO:0061630	ubiquitin protein ligase activity
0.36	GO:0008270	zinc ion binding

0.61

GO:0005634

nucleus

sp|P25155|FA10_CHICK
Coagulation factor X
Search

F10

0.88	Coagulation factor IX

0.73	GO:0007596	blood coagulation
0.60	GO:0006508	proteolysis
0.59	GO:0051897	positive regulation of protein kinase B signaling
0.35	GO:0017187	peptidyl-glutamic acid carboxylation
0.35	GO:0072376	protein activation cascade
0.35	GO:0010952	positive regulation of peptidase activity
0.35	GO:0030335	positive regulation of cell migration
0.35	GO:0006888	ER to Golgi vesicle-mediated transport
0.34	GO:0009405	pathogenesis
0.34	GO:0051604	protein maturation

0.68	GO:0004252	serine-type endopeptidase activity
0.64	GO:0005509	calcium ion binding
0.54	GO:0005543	phospholipid binding
0.35	GO:0016504	peptidase activator activity
0.35	GO:0090729	toxin activity
0.33	GO:0005515	protein binding

0.61	GO:0005576	extracellular region
0.36	GO:0005796	Golgi lumen
0.36	GO:0031233	intrinsic component of external side of plasma membrane
0.35	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.68

GO:0004252

sp|P25207|NFYB_CHICK
Nuclear transcription factor Y subunit beta
Search

NFYB

0.93	Nuclear transcription factor Y subunit beta

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:1990830	cellular response to leukemia inhibitory factor
0.48	GO:0051254	positive regulation of RNA metabolic process
0.47	GO:0010557	positive regulation of macromolecule biosynthetic process
0.47	GO:0031328	positive regulation of cellular biosynthetic process
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:0045540	regulation of cholesterol biosynthetic process

0.73	GO:0046982	protein heterodimerization activity
0.64	GO:0043565	sequence-specific DNA binding
0.52	GO:0070491	repressing transcription factor binding
0.52	GO:0035326	enhancer binding
0.49	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0003690	double-stranded DNA binding
0.43	GO:0003700	DNA binding transcription factor activity
0.37	GO:0032403	protein complex binding

0.60	GO:0005634	nucleus
0.48	GO:0005667	transcription factor complex
0.47	GO:0032993	protein-DNA complex
0.41	GO:0044446	intracellular organelle part
0.35	GO:0043233	organelle lumen

sp|P25324|THTR_CHICK
Thiosulfate sulfurtransferase
Search

TST

0.51	Thiosulfate sulfurtransferase

0.59	GO:0035928	rRNA import into mitochondrion
0.52	GO:0030855	epithelial cell differentiation
0.37	GO:0009440	cyanate catabolic process
0.36	GO:0019346	transsulfuration
0.36	GO:0021510	spinal cord development
0.36	GO:0001889	liver development
0.35	GO:0001822	kidney development
0.35	GO:0070813	hydrogen sulfide metabolic process
0.35	GO:0009403	toxin biosynthetic process
0.34	GO:0044272	sulfur compound biosynthetic process

0.79	GO:0004792	thiosulfate sulfurtransferase activity
0.53	GO:0008097	5S rRNA binding
0.36	GO:0016784	3-mercaptopyruvate sulfurtransferase activity
0.35	GO:0042802	identical protein binding

0.45	GO:0044429	mitochondrial part
0.45	GO:0019866	organelle inner membrane
0.38	GO:0070062	extracellular exosome
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0043005	neuron projection
0.35	GO:0045202	synapse
0.35	GO:0030054	cell junction
0.34	GO:0005829	cytosol

0.79	EC:2.8.1.1	GO:0004792
0.79	KEGG:R01931	GO:0004792

sp|P25429|BDNF_CHICK
Brain-derived neurotrophic factor
Search

BDNF

0.59	Brain-derived neurotrophic factor

0.76	GO:0010469	regulation of receptor activity
0.41	GO:1900122	positive regulation of receptor binding
0.41	GO:0048672	positive regulation of collateral sprouting
0.41	GO:0048668	collateral sprouting
0.40	GO:0051965	positive regulation of synapse assembly
0.40	GO:0007416	synapse assembly
0.36	GO:0009628	response to abiotic stimulus
0.35	GO:0032355	response to estradiol
0.34	GO:0006950	response to stress
0.34	GO:0043524	negative regulation of neuron apoptotic process

0.78	GO:0008083	growth factor activity
0.35	GO:0005169	neurotrophin TRKB receptor binding

0.66	GO:0005576	extracellular region
0.39	GO:0016607	nuclear speck
0.36	GO:0005739	mitochondrion
0.34	GO:0030424	axon
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0031410	cytoplasmic vesicle

sp|P25433|NTF3_CHICK
Neurotrophin-3
Search

NTF3

0.64	Neurotrophin-3

0.75	GO:0010469	regulation of receptor activity
0.54	GO:0050930	induction of positive chemotaxis
0.54	GO:2000251	positive regulation of actin cytoskeleton reorganization
0.54	GO:0032148	activation of protein kinase B activity
0.54	GO:0002092	positive regulation of receptor internalization
0.53	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation
0.53	GO:0050918	positive chemotaxis
0.52	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.52	GO:0090630	activation of GTPase activity
0.52	GO:0000187	activation of MAPK activity

0.85	GO:0005165	neurotrophin receptor binding
0.78	GO:0008083	growth factor activity
0.54	GO:0042056	chemoattractant activity
0.35	GO:0048406	nerve growth factor binding

0.40	GO:0031410	cytoplasmic vesicle
0.38	GO:0005576	extracellular region
0.34	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016020	membrane

sp|P25692|KRCL_CHICK
Claw keratin
Search

0.74	Claw keratin

0.69

GO:0007010

cytoskeleton organization

0.75

GO:0005200

structural constituent of cytoskeleton

0.77	GO:0005882	intermediate filament
0.30	GO:0031224	intrinsic component of membrane

sp|P26007|ITA6_CHICK
Integrin alpha-6
Search

0.86	LOW QUALITY PROTEIN: integrin alpha-6

0.79	GO:0007229	integrin-mediated signaling pathway
0.72	GO:0007155	cell adhesion
0.40	GO:0009888	tissue development
0.40	GO:0048513	animal organ development
0.39	GO:0035878	nail development
0.39	GO:0061061	muscle structure development
0.39	GO:0046847	filopodium assembly
0.38	GO:0050873	brown fat cell differentiation
0.38	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.38	GO:0048565	digestive tract development

0.39	GO:0038132	neuregulin binding
0.39	GO:0031994	insulin-like growth factor I binding
0.38	GO:0005178	integrin binding
0.38	GO:0045296	cadherin binding
0.30	GO:0043169	cation binding

0.81	GO:0008305	integrin complex
0.39	GO:0030056	hemidesmosome
0.38	GO:0009925	basal plasma membrane
0.38	GO:0005604	basement membrane
0.38	GO:0009897	external side of plasma membrane

sp|P26008|ITAV_CHICK
Integrin alpha-V
Search

ITGAV

0.89	Alpha v integrin subunit variant

0.76	GO:0007229	integrin-mediated signaling pathway
0.69	GO:0007155	cell adhesion
0.62	GO:2000536	negative regulation of entry of bacterium into host cell
0.61	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process
0.60	GO:0038027	apolipoprotein A-I-mediated signaling pathway
0.60	GO:0038044	transforming growth factor-beta secretion
0.60	GO:0050748	negative regulation of lipoprotein metabolic process
0.60	GO:0010745	negative regulation of macrophage derived foam cell differentiation
0.59	GO:0010888	negative regulation of lipid storage
0.58	GO:0032369	negative regulation of lipid transport

0.61	GO:1990430	extracellular matrix protein binding
0.61	GO:0038132	neuregulin binding
0.60	GO:0019960	C-X3-C chemokine binding
0.59	GO:0031994	insulin-like growth factor I binding
0.59	GO:0001968	fibronectin binding
0.58	GO:0001846	opsonin binding
0.58	GO:0017134	fibroblast growth factor binding
0.57	GO:0005080	protein kinase C binding
0.57	GO:0005178	integrin binding
0.56	GO:0050840	extracellular matrix binding

0.77	GO:0008305	integrin complex
0.61	GO:0035868	alphav-beta3 integrin-HMGB1 complex
0.60	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex
0.59	GO:0031258	lamellipodium membrane
0.59	GO:0031528	microvillus membrane
0.59	GO:0031527	filopodium membrane
0.57	GO:0032587	ruffle membrane
0.56	GO:0005925	focal adhesion
0.54	GO:0009897	external side of plasma membrane
0.48	GO:0005829	cytosol

sp|P26009|ITA8_CHICK
Integrin alpha-8
Search

ITGA8

0.95	Integrin alpha-V

0.77	GO:0007229	integrin-mediated signaling pathway
0.69	GO:0007155	cell adhesion
0.60	GO:0048333	mesodermal cell differentiation
0.58	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
0.57	GO:0001822	kidney development
0.57	GO:0000904	cell morphogenesis involved in differentiation
0.56	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.56	GO:0048745	smooth muscle tissue development
0.55	GO:0048562	embryonic organ morphogenesis
0.54	GO:0007613	memory

0.40	GO:0001968	fibronectin binding
0.38	GO:1990430	extracellular matrix protein binding
0.38	GO:0038132	neuregulin binding
0.38	GO:0019960	C-X3-C chemokine binding
0.38	GO:0001846	opsonin binding
0.38	GO:0031994	insulin-like growth factor I binding
0.38	GO:0017134	fibroblast growth factor binding
0.38	GO:0005080	protein kinase C binding
0.37	GO:0005178	integrin binding
0.37	GO:0050840	extracellular matrix binding

0.78	GO:0008305	integrin complex
0.55	GO:0009986	cell surface
0.52	GO:0045177	apical part of cell
0.51	GO:0005783	endoplasmic reticulum
0.41	GO:0031256	leading edge membrane
0.41	GO:0031253	cell projection membrane
0.40	GO:0005925	focal adhesion
0.40	GO:0043204	perikaryon
0.40	GO:0043197	dendritic spine
0.39	GO:0014069	postsynaptic density

sp|P26152|ACHA5_CHICK
Neuronal acetylcholine receptor subunit alpha-5
Search

CHRNA5

0.91	Cholinergic receptor nicotinic alpha 5 subunit

0.80	GO:0060079	excitatory postsynaptic potential
0.66	GO:0035094	response to nicotine
0.60	GO:0034220	ion transmembrane transport
0.59	GO:0030534	adult behavior
0.52	GO:0007271	synaptic transmission, cholinergic
0.52	GO:0007274	neuromuscular synaptic transmission
0.42	GO:0006812	cation transport

0.83	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.53	GO:0042166	acetylcholine binding

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.64	GO:0005892	acetylcholine-gated channel complex

sp|P26153|ACHB4_CHICK
Neuronal acetylcholine receptor subunit beta-4 (Fragment)
Search

CHRNB4

0.94	LOW QUALITY PROTEIN: neuronal acetylcholine receptor subunit beta-2

0.80	GO:0060079	excitatory postsynaptic potential
0.62	GO:0060084	synaptic transmission involved in micturition
0.60	GO:0034220	ion transmembrane transport
0.60	GO:0035094	response to nicotine
0.55	GO:0006939	smooth muscle contraction
0.55	GO:0001508	action potential
0.54	GO:0030534	adult behavior
0.53	GO:0007626	locomotory behavior
0.53	GO:0051971	positive regulation of transmission of nerve impulse
0.51	GO:0007271	synaptic transmission, cholinergic

0.83	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.56	GO:0042166	acetylcholine binding
0.39	GO:0046982	protein heterodimerization activity

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.63	GO:0005892	acetylcholine-gated channel complex
0.44	GO:0009897	external side of plasma membrane
0.39	GO:0043005	neuron projection
0.36	GO:0044853	plasma membrane raft
0.35	GO:0035579	specific granule membrane
0.35	GO:0070821	tertiary granule membrane
0.35	GO:0043204	perikaryon
0.34	GO:0120038	plasma membrane bounded cell projection part

sp|P26261|SDC3_CHICK
Syndecan-3
Search

SDC3

0.82

Syndecan

0.45	GO:0016477	cell migration
0.44	GO:0042060	wound healing
0.43	GO:0048627	myoblast development
0.42	GO:1903553	positive regulation of extracellular exosome assembly
0.42	GO:1903543	positive regulation of exosomal secretion
0.41	GO:0060070	canonical Wnt signaling pathway
0.40	GO:0055002	striated muscle cell development
0.40	GO:0035988	chondrocyte proliferation
0.40	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.39	GO:0003419	growth plate cartilage chondrocyte proliferation

0.51	GO:0042802	identical protein binding
0.41	GO:0008022	protein C-terminus binding
0.36	GO:0019838	growth factor binding
0.33	GO:0050840	extracellular matrix binding
0.32	GO:0008234	cysteine-type peptidase activity
0.32	GO:0003723	RNA binding

0.49	GO:0031012	extracellular matrix
0.46	GO:0009986	cell surface
0.39	GO:0098552	side of membrane
0.38	GO:0005796	Golgi lumen
0.37	GO:0044459	plasma membrane part
0.36	GO:0043202	lysosomal lumen
0.35	GO:0070062	extracellular exosome
0.34	GO:0030424	axon
0.34	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.32

GO:0008234

sp|P26446|PARP1_CHICK
Poly [ADP-ribose] polymerase 1
Search

PARP1

0.57	Poly [ADP-ribose] polymerase

0.83	GO:0006471	protein ADP-ribosylation
0.62	GO:1990966	ATP generation from poly-ADP-D-ribose
0.61	GO:1903518	positive regulation of single strand break repair
0.60	GO:2001170	negative regulation of ATP biosynthetic process
0.58	GO:0043504	mitochondrial DNA repair
0.56	GO:0018209	peptidyl-serine modification
0.56	GO:0032869	cellular response to insulin stimulus
0.56	GO:0034644	cellular response to UV
0.53	GO:0006915	apoptotic process
0.53	GO:0006302	double-strand break repair

0.81	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.65	GO:0051287	NAD binding
0.63	GO:1990404	protein ADP-ribosylase activity
0.62	GO:0008270	zinc ion binding
0.57	GO:0047485	protein N-terminus binding
0.54	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.54	GO:0003677	DNA binding
0.53	GO:0019901	protein kinase binding
0.52	GO:0001067	regulatory region nucleic acid binding
0.51	GO:0042802	identical protein binding

0.59	GO:0005634	nucleus
0.52	GO:0005667	transcription factor complex
0.50	GO:0032993	protein-DNA complex
0.48	GO:0070013	intracellular organelle lumen
0.48	GO:0012505	endomembrane system
0.45	GO:0031967	organelle envelope
0.45	GO:0005739	mitochondrion
0.44	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.81

EC:2.4.2.30

GO:0003950

sp|P26584|HMGB2_CHICK
High mobility group protein B2
Search

HMGB2

0.89	High mobility group box 2

0.68	GO:0002437	inflammatory response to antigenic stimulus
0.65	GO:0050830	defense response to Gram-positive bacterium
0.64	GO:0050829	defense response to Gram-negative bacterium
0.63	GO:0032496	response to lipopolysaccharide
0.62	GO:0072091	regulation of stem cell proliferation
0.58	GO:0050767	regulation of neurogenesis
0.58	GO:0032392	DNA geometric change
0.56	GO:0045654	positive regulation of megakaryocyte differentiation
0.56	GO:0043388	positive regulation of DNA binding
0.55	GO:0001938	positive regulation of endothelial cell proliferation

0.72	GO:0008301	DNA binding, bending
0.70	GO:0000400	four-way junction DNA binding
0.68	GO:0097100	supercoiled DNA binding
0.62	GO:0001158	enhancer sequence-specific DNA binding
0.56	GO:0050786	RAGE receptor binding
0.56	GO:0008134	transcription factor binding
0.55	GO:0000405	bubble DNA binding
0.55	GO:0042056	chemoattractant activity
0.49	GO:0003684	damaged DNA binding
0.48	GO:0019904	protein domain specific binding

0.61	GO:0005634	nucleus
0.58	GO:0005615	extracellular space
0.54	GO:0000785	chromatin
0.52	GO:0000793	condensed chromosome
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0070013	intracellular organelle lumen
0.43	GO:0043234	protein complex
0.38	GO:0017053	transcriptional repressor complex
0.38	GO:0009986	cell surface
0.36	GO:0044459	plasma membrane part

0.35

EC:4

GO:0016829

sp|P26652|TIMP3_CHICK
Metalloproteinase inhibitor 3
Search

TIMP3

0.96	Metalloproteinase inhibitor 3

0.74	GO:0010951	negative regulation of endopeptidase activity
0.54	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway
0.54	GO:0051045	negative regulation of membrane protein ectodomain proteolysis
0.52	GO:1904683	regulation of metalloendopeptidase activity
0.52	GO:1905049	negative regulation of metallopeptidase activity
0.51	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.45	GO:0071310	cellular response to organic substance
0.36	GO:0051593	response to folic acid
0.36	GO:0002576	platelet degranulation
0.35	GO:0043627	response to estrogen

0.84	GO:0008191	metalloendopeptidase inhibitor activity
0.44	GO:0002020	protease binding
0.39	GO:0008270	zinc ion binding

0.65	GO:0005576	extracellular region
0.36	GO:0031089	platelet dense granule lumen
0.34	GO:0005634	nucleus

sp|P26677|PPLA_CHICK
Cardiac phospholamban
Search

PLN

0.97	Cardiac phospholamban

0.77	GO:0006816	calcium ion transport
0.72	GO:0043086	negative regulation of catalytic activity
0.67	GO:1901877	negative regulation of calcium ion binding
0.67	GO:0086023	adrenergic receptor signaling pathway involved in heart process
0.66	GO:0086092	regulation of the force of heart contraction by cardiac conduction
0.65	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
0.65	GO:1901894	regulation of calcium-transporting ATPase activity
0.65	GO:1901077	regulation of relaxation of muscle
0.64	GO:0010459	negative regulation of heart rate
0.64	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity

0.85	GO:0005246	calcium channel regulator activity
0.82	GO:0042030	ATPase inhibitor activity
0.38	GO:0051117	ATPase binding
0.36	GO:0042802	identical protein binding

0.83	GO:0033017	sarcoplasmic reticulum membrane
0.66	GO:0090534	calcium ion-transporting ATPase complex
0.60	GO:0031966	mitochondrial membrane
0.39	GO:0031982	vesicle
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0043234	protein complex

sp|P26697|GSTA3_CHICK
Glutathione S-transferase 3
Search

0.42	Glutathione S-transferase class-alpha

0.44	GO:0043390	aflatoxin B1 metabolic process
0.42	GO:0006749	glutathione metabolic process
0.41	GO:0098754	detoxification
0.40	GO:0043651	linoleic acid metabolic process
0.39	GO:0060429	epithelium development
0.38	GO:0030154	cell differentiation
0.37	GO:1901685	glutathione derivative metabolic process
0.37	GO:0070887	cellular response to chemical stimulus
0.35	GO:1901377	organic heteropentacyclic compound catabolic process
0.35	GO:0070671	response to interleukin-12

0.77	GO:0004364	glutathione transferase activity
0.38	GO:0004602	glutathione peroxidase activity
0.34	GO:0043295	glutathione binding
0.33	GO:0005515	protein binding
0.32	GO:0008144	drug binding

0.43	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome
0.35	GO:0005640	nuclear outer membrane

0.77

GO:0004364

sp|P26932|CNN1_CHICK
Calponin-1
Search

CNN2

0.64

Calponin

0.82	GO:0031032	actomyosin structure organization
0.56	GO:1904706	negative regulation of vascular smooth muscle cell proliferation
0.46	GO:0043535	regulation of blood vessel endothelial cell migration
0.44	GO:0043408	regulation of MAPK cascade
0.35	GO:0006940	regulation of smooth muscle contraction

0.78	GO:0005516	calmodulin binding
0.74	GO:0003779	actin binding

0.57	GO:0005856	cytoskeleton
0.36	GO:0005925	focal adhesion

sp|P26990|ARF6_CHICK
ADP-ribosylation factor 6
Search

ARF6

0.69	ADP-ribosylation factor

0.56	GO:0035020	regulation of Rac protein signal transduction
0.56	GO:0036010	protein localization to endosome
0.56	GO:0033028	myeloid cell apoptotic process
0.56	GO:0001889	liver development
0.55	GO:0097178	ruffle assembly
0.55	GO:0097284	hepatocyte apoptotic process
0.54	GO:0051489	regulation of filopodium assembly
0.54	GO:0034394	protein localization to cell surface
0.53	GO:0032456	endocytic recycling
0.53	GO:0060998	regulation of dendritic spine development

0.66	GO:0005525	GTP binding
0.56	GO:0031996	thioesterase binding
0.52	GO:0047485	protein N-terminus binding
0.36	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity
0.35	GO:0031681	G-protein beta-subunit binding
0.34	GO:0003924	GTPase activity

0.56	GO:0031527	filopodium membrane
0.56	GO:0090543	Flemming body
0.55	GO:0032154	cleavage furrow
0.55	GO:0055038	recycling endosome membrane
0.53	GO:0001726	ruffle
0.52	GO:0030139	endocytic vesicle
0.51	GO:0043209	myelin sheath
0.50	GO:0005938	cell cortex
0.39	GO:0005769	early endosome
0.38	GO:0005829	cytosol

0.36

EC:2.4.2.31

GO:0003956

sp|P27003|S10AA_CHICK
Protein S100-A10
Search

S100A10

0.97	S100 calcium binding protein A10

0.56	GO:0051894	positive regulation of focal adhesion assembly
0.56	GO:0051290	protein heterotetramerization
0.56	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.55	GO:0051496	positive regulation of stress fiber assembly
0.55	GO:0001765	membrane raft assembly
0.53	GO:0072659	protein localization to plasma membrane
0.53	GO:0006900	vesicle budding from membrane
0.51	GO:0051099	positive regulation of binding
0.50	GO:0043547	positive regulation of GTPase activity
0.45	GO:0042127	regulation of cell proliferation

0.68	GO:0005509	calcium ion binding
0.54	GO:0044325	ion channel binding
0.51	GO:0042803	protein homodimerization activity
0.49	GO:0048306	calcium-dependent protein binding
0.36	GO:0008289	lipid binding
0.33	GO:0003723	RNA binding
0.32	GO:0046914	transition metal ion binding

0.52	GO:0045121	membrane raft
0.49	GO:0019897	extrinsic component of plasma membrane
0.46	GO:0005576	extracellular region
0.38	GO:0005783	endoplasmic reticulum
0.36	GO:0031982	vesicle
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P27042|LYG_CHICK
Lysozyme g
Search

0.96	G-type lysozyme

0.76	GO:0016998	cell wall macromolecule catabolic process
0.73	GO:0009253	peptidoglycan catabolic process
0.43	GO:0042742	defense response to bacterium
0.42	GO:0019835	cytolysis
0.36	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.35	GO:0010628	positive regulation of gene expression

0.77

GO:0003796

lysozyme activity

0.40	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

0.77

EC:3.2.1.17

GO:0003796

sp|P27043|ANGI_CHICK
Angiogenin
Search

RNASE4

0.86	Leukocyte ribonuclease A-1

0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.58	GO:0050830	defense response to Gram-positive bacterium
0.58	GO:0050829	defense response to Gram-negative bacterium
0.57	GO:0001525	angiogenesis
0.48	GO:0016070	RNA metabolic process
0.43	GO:0009267	cellular response to starvation

0.66	GO:0004519	endonuclease activity
0.59	GO:0004540	ribonuclease activity
0.51	GO:0003676	nucleic acid binding

0.52	GO:0005576	extracellular region
0.42	GO:0005737	cytoplasm
0.38	GO:0031982	vesicle

sp|P27089|XPA_CHICK
DNA repair protein complementing XP-A cells homolog
Search

XPA

0.94	DNA repair protein complementing XP-A cells

0.73	GO:0006289	nucleotide-excision repair
0.57	GO:0009650	UV protection
0.54	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.54	GO:0035264	multicellular organism growth
0.53	GO:0034504	protein localization to nucleus
0.50	GO:0070914	UV-damage excision repair
0.48	GO:0006979	response to oxidative stress
0.48	GO:0036297	interstrand cross-link repair
0.47	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.47	GO:0009636	response to toxic substance

0.73	GO:0003684	damaged DNA binding
0.51	GO:0019904	protein domain specific binding
0.51	GO:0042803	protein homodimerization activity
0.35	GO:0046872	metal ion binding
0.34	GO:0003690	double-stranded DNA binding
0.34	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.55	GO:0045171	intercellular bridge
0.51	GO:0030894	replisome
0.48	GO:0031974	membrane-enclosed lumen
0.45	GO:1990391	DNA repair complex
0.45	GO:0043234	protein complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.34

EC:2.3.1.51

GO:0003841

sp|P27092|INHBA_CHICK
Inhibin beta A chain
Search

INHBA

0.97	Inhibin beta A subunit

0.76	GO:0010469	regulation of receptor activity
0.62	GO:0042701	progesterone secretion
0.62	GO:0046880	regulation of follicle-stimulating hormone secretion
0.61	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.61	GO:0042541	hemoglobin biosynthetic process
0.60	GO:0060279	positive regulation of ovulation
0.60	GO:0032924	activin receptor signaling pathway
0.60	GO:0045648	positive regulation of erythrocyte differentiation
0.59	GO:0021773	striatal medium spiny neuron differentiation
0.59	GO:0061029	eyelid development in camera-type eye

0.78	GO:0008083	growth factor activity
0.72	GO:0005179	hormone activity
0.59	GO:0070699	type II activin receptor binding
0.56	GO:0017046	peptide hormone binding
0.56	GO:0005125	cytokine activity
0.50	GO:0042802	identical protein binding
0.47	GO:0005160	transforming growth factor beta receptor binding
0.42	GO:0034711	inhibin binding
0.38	GO:0046982	protein heterodimerization activity

0.66	GO:0005576	extracellular region
0.52	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0043234	protein complex

sp|P27093|INHBB_CHICK
Inhibin beta B chain
Search

INHBB

0.95	Inhibin beta B subunit

0.75	GO:0010469	regulation of receptor activity
0.61	GO:0032686	negative regulation of hepatocyte growth factor production
0.61	GO:0048176	regulation of hepatocyte growth factor biosynthetic process
0.61	GO:0046882	negative regulation of follicle-stimulating hormone secretion
0.60	GO:0046881	positive regulation of follicle-stimulating hormone secretion
0.59	GO:0060279	positive regulation of ovulation
0.58	GO:0042036	negative regulation of cytokine biosynthetic process
0.58	GO:0032924	activin receptor signaling pathway
0.57	GO:0046676	negative regulation of insulin secretion
0.55	GO:0045444	fat cell differentiation

0.78	GO:0008083	growth factor activity
0.77	GO:0005179	hormone activity
0.51	GO:0042803	protein homodimerization activity
0.49	GO:0005160	transforming growth factor beta receptor binding
0.47	GO:0005125	cytokine activity
0.36	GO:0034711	inhibin binding
0.34	GO:0046982	protein heterodimerization activity
0.34	GO:0046812	host cell surface binding
0.33	GO:0003924	GTPase activity
0.33	GO:0005525	GTP binding

0.66	GO:0005576	extracellular region
0.54	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0071944	cell periphery
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|P27118|DCOR_CHICK
Ornithine decarboxylase (Fragment)
Search

ODC1

0.48	Ornithine decarboxylase

0.73	GO:0006596	polyamine biosynthetic process
0.57	GO:0009445	putrescine metabolic process
0.55	GO:0001822	kidney development
0.54	GO:0006591	ornithine metabolic process
0.54	GO:0042176	regulation of protein catabolic process
0.54	GO:0008284	positive regulation of cell proliferation
0.53	GO:0009615	response to virus
0.45	GO:0042462	eye photoreceptor cell development
0.35	GO:0006521	regulation of cellular amino acid metabolic process

0.60	GO:0004586	ornithine decarboxylase activity
0.53	GO:0042803	protein homodimerization activity

0.49	GO:0005829	cytosol
0.38	GO:0048471	perinuclear region of cytoplasm

0.60	EC:4.1.1.17	GO:0004586
0.60	KEGG:R00670	GO:0004586

sp|P27177|PRIO_CHICK
Major prion protein homolog
Search

PRNP

0.78	Prion protein PrP

0.78	GO:0051260	protein homooligomerization
0.55	GO:0098737	protein insertion into plasma membrane
0.55	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.53	GO:0010870	positive regulation of receptor biosynthetic process
0.51	GO:1902938	regulation of intracellular calcium activated chloride channel activity
0.50	GO:0071280	cellular response to copper ion
0.50	GO:1904646	cellular response to amyloid-beta
0.50	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.49	GO:0043525	positive regulation of neuron apoptotic process
0.49	GO:1902951	negative regulation of dendritic spine maintenance

0.53	GO:0046872	metal ion binding
0.51	GO:0031802	type 5 metabotropic glutamate receptor binding
0.49	GO:0001540	amyloid-beta binding
0.47	GO:0002020	protease binding
0.45	GO:0008017	microtubule binding
0.45	GO:0032403	protein complex binding
0.45	GO:0042802	identical protein binding
0.44	GO:0005539	glycosaminoglycan binding
0.41	GO:0004872	receptor activity
0.40	GO:0004871	signal transducer activity

0.55	GO:0005886	plasma membrane
0.52	GO:0043083	synaptic cleft
0.52	GO:0005605	basal lamina
0.50	GO:0106003	amyloid-beta complex
0.49	GO:0098857	membrane microdomain
0.48	GO:0016234	inclusion body
0.47	GO:0030425	dendrite
0.47	GO:0031965	nuclear membrane
0.45	GO:0009986	cell surface
0.45	GO:0005794	Golgi apparatus

sp|P27463|AL1A1_CHICK
Retinal dehydrogenase 1
Search

ALDH1A1

0.92	Retinal dehydrogenase 1

0.53	GO:0055114	oxidation-reduction process
0.52	GO:0042572	retinol metabolic process
0.45	GO:0042905	9-cis-retinoic acid metabolic process
0.44	GO:0002138	retinoic acid biosynthetic process
0.44	GO:0031076	embryonic camera-type eye development
0.43	GO:0016331	morphogenesis of embryonic epithelium
0.42	GO:0043065	positive regulation of apoptotic process
0.41	GO:0009887	animal organ morphogenesis
0.41	GO:0007494	midgut development
0.40	GO:0032355	response to estradiol

0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.40	GO:0051287	NAD binding
0.39	GO:0016918	retinal binding
0.37	GO:0005497	androgen binding
0.35	GO:0005096	GTPase activator activity
0.35	GO:0042802	identical protein binding

0.47	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome
0.37	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005634	nucleus

0.69

GO:0016620

sp|P27607|PGH2_CHICK
Prostaglandin G/H synthase 2
Search

PTGS2

0.96	Prostaglandin-endoperoxide synthase 2 (Prostaglandin G/H synthase and cyclooxygenase)

0.86	GO:0019371	cyclooxygenase pathway
0.83	GO:0008217	regulation of blood pressure
0.80	GO:0006954	inflammatory response
0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.58	GO:0071471	cellular response to non-ionic osmotic stress
0.58	GO:0031394	positive regulation of prostaglandin biosynthetic process
0.57	GO:1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
0.57	GO:0031622	positive regulation of fever generation
0.57	GO:0090336	positive regulation of brown fat cell differentiation

0.86	GO:0004666	prostaglandin-endoperoxide synthase activity
0.72	GO:0004601	peroxidase activity
0.63	GO:0020037	heme binding
0.49	GO:0042803	protein homodimerization activity
0.48	GO:0019899	enzyme binding
0.40	GO:0051213	dioxygenase activity
0.36	GO:0046872	metal ion binding
0.36	GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen

0.51	GO:0043005	neuron projection
0.49	GO:0005783	endoplasmic reticulum
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0031984	organelle subcompartment
0.38	GO:0031090	organelle membrane
0.37	GO:0005901	caveola
0.34	GO:0043234	protein complex
0.34	GO:0097731	9+0 non-motile cilium
0.34	GO:0044441	ciliary part
0.33	GO:0070013	intracellular organelle lumen

0.86	EC:1.14.99.1	GO:0004666
0.72	KEGG:R03532	GO:0004601

sp|P27673|TNNI3_CHICK
Troponin I, cardiac muscle (Fragment)
Search

TNNI3

0.90	Troponin I slow skeletal muscle

0.56	GO:0060048	cardiac muscle contraction
0.56	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.54	GO:0090257	regulation of muscle system process
0.53	GO:0001980	regulation of systemic arterial blood pressure by ischemic conditions
0.51	GO:0003009	skeletal muscle contraction
0.49	GO:0001570	vasculogenesis
0.48	GO:0019722	calcium-mediated signaling
0.48	GO:0008016	regulation of heart contraction
0.47	GO:0006874	cellular calcium ion homeostasis
0.47	GO:0032780	negative regulation of ATPase activity

0.52	GO:0031014	troponin T binding
0.51	GO:0030172	troponin C binding
0.50	GO:0019855	calcium channel inhibitor activity
0.49	GO:0048306	calcium-dependent protein binding
0.48	GO:0003779	actin binding
0.46	GO:0019901	protein kinase binding
0.46	GO:0019904	protein domain specific binding
0.45	GO:0032403	protein complex binding
0.37	GO:0046872	metal ion binding
0.33	GO:0016887	ATPase activity

0.84	GO:0005861	troponin complex
0.51	GO:0097512	cardiac myofibril
0.34	GO:0005829	cytosol

0.33

GO:0016887

sp|P27731|TTHY_CHICK
Transthyretin
Search

TTR

0.95	Transthyretin

0.85	GO:0070327	thyroid hormone transport
0.85	GO:0042572	retinol metabolic process
0.46	GO:0010469	regulation of receptor activity
0.43	GO:0006144	purine nucleobase metabolic process
0.39	GO:0051262	protein tetramerization
0.38	GO:0051260	protein homooligomerization
0.36	GO:0001555	oocyte growth
0.36	GO:0043627	response to estrogen
0.35	GO:0042403	thyroid hormone metabolic process
0.35	GO:0043312	neutrophil degranulation

0.86	GO:0070324	thyroid hormone binding
0.47	GO:0005179	hormone activity
0.47	GO:0042802	identical protein binding
0.38	GO:0046982	protein heterodimerization activity
0.34	GO:0019904	protein domain specific binding
0.33	GO:0015643	toxic substance binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0036094	small molecule binding
0.31	GO:0097159	organic cyclic compound binding

0.66	GO:0005576	extracellular region
0.36	GO:0060417	yolk
0.36	GO:0031982	vesicle
0.36	GO:0043234	protein complex
0.35	GO:0005766	primary lysosome
0.35	GO:0005775	vacuolar lumen
0.33	GO:0012505	endomembrane system
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P27921|JUND_CHICK
Transcription factor jun-D
Search

JUND

0.91	Transcription factor jun-D

0.63	GO:0006357	regulation of transcription by RNA polymerase II
0.50	GO:0009612	response to mechanical stimulus
0.49	GO:0071277	cellular response to calcium ion
0.49	GO:0045597	positive regulation of cell differentiation
0.49	GO:0051591	response to cAMP
0.49	GO:0045893	positive regulation of transcription, DNA-templated
0.47	GO:0042127	regulation of cell proliferation
0.47	GO:0002076	osteoblast development
0.47	GO:0032496	response to lipopolysaccharide
0.47	GO:0071495	cellular response to endogenous stimulus

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.50	GO:0001067	regulatory region nucleic acid binding
0.49	GO:0003713	transcription coactivator activity
0.48	GO:0008134	transcription factor binding
0.44	GO:0019899	enzyme binding
0.42	GO:0008013	beta-catenin binding
0.41	GO:0070412	R-SMAD binding
0.39	GO:0003682	chromatin binding
0.39	GO:0005096	GTPase activator activity

0.55	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.46	GO:0000785	chromatin
0.44	GO:0070013	intracellular organelle lumen
0.40	GO:0017053	transcriptional repressor complex
0.36	GO:0032993	protein-DNA complex
0.32	GO:0030529	intracellular ribonucleoprotein complex

sp|P28173|PUR1_CHICK
Amidophosphoribosyltransferase
Search

PPAT

0.52	Amidophosphoribosyltransferase

0.73	GO:0009113	purine nucleobase biosynthetic process
0.65	GO:0009116	nucleoside metabolic process
0.65	GO:0006189	'de novo' IMP biosynthetic process
0.39	GO:0007595	lactation
0.39	GO:0031100	animal organ regeneration
0.39	GO:0060135	maternal process involved in female pregnancy
0.39	GO:0051289	protein homotetramerization
0.39	GO:0032869	cellular response to insulin stimulus
0.39	GO:0000082	G1/S transition of mitotic cell cycle
0.38	GO:0006543	glutamine catabolic process

0.77	GO:0004044	amidophosphoribosyltransferase activity
0.61	GO:0051536	iron-sulfur cluster binding
0.52	GO:0046872	metal ion binding

0.35

GO:0005829

cytosol

0.77	EC:2.4.2.14	GO:0004044
0.77	KEGG:R01072	GO:0004044

sp|P28238|MIP_CHICK
Lens fiber major intrinsic protein
Search

MIP

0.97	Major intrinsic protein of eye lens fiber

0.65	GO:0006833	water transport
0.61	GO:0043010	camera-type eye development
0.61	GO:1990349	gap junction-mediated intercellular transport
0.56	GO:0051289	protein homotetramerization
0.55	GO:0055085	transmembrane transport
0.52	GO:0003008	system process
0.52	GO:0045785	positive regulation of cell adhesion
0.47	GO:0015670	carbon dioxide transport
0.46	GO:0032941	secretion by tissue
0.46	GO:0007589	body fluid secretion

0.69	GO:0022803	passive transmembrane transporter activity
0.66	GO:0005372	water transmembrane transporter activity
0.56	GO:0005212	structural constituent of eye lens
0.43	GO:0005515	protein binding
0.37	GO:0015168	glycerol transmembrane transporter activity

0.54	GO:0016324	apical plasma membrane
0.52	GO:0005783	endoplasmic reticulum
0.47	GO:0009925	basal plasma membrane
0.45	GO:0005902	microvillus
0.45	GO:0005887	integral component of plasma membrane
0.43	GO:0005921	gap junction
0.38	GO:0070062	extracellular exosome
0.37	GO:0016328	lateral plasma membrane
0.35	GO:0055037	recycling endosome

sp|P28318|M126_CHICK
Protein MRP-126
Search

sp|P28337|GCST_CHICK
Aminomethyltransferase, mitochondrial
Search

AMT

0.55	Aminomethyltransferase, mitochondrial

0.74	GO:0006546	glycine catabolic process
0.62	GO:0032259	methylation

0.79	GO:0004047	aminomethyltransferase activity
0.67	GO:0008483	transaminase activity
0.36	GO:0031405	lipoic acid binding

0.59	GO:0005739	mitochondrion
0.48	GO:0005654	nucleoplasm
0.33	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:2.1.2.10

GO:0004047

sp|P28361|MSX1_CHICK
Homeobox protein MSX-1
Search

MSX1

0.93	Homeobox protein GHOX-7

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0035880	embryonic nail plate morphogenesis
0.53	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
0.51	GO:0060325	face morphogenesis
0.50	GO:2001055	positive regulation of mesenchymal cell apoptotic process
0.50	GO:0090427	activation of meiosis
0.49	GO:0030308	negative regulation of cell growth
0.49	GO:0042475	odontogenesis of dentin-containing tooth

0.64	GO:0043565	sequence-specific DNA binding
0.50	GO:0002039	p53 binding
0.47	GO:0035326	enhancer binding
0.46	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.46	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.45	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.43	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.43	GO:0070013	intracellular organelle lumen
0.40	GO:0044446	intracellular organelle part
0.34	GO:0005667	transcription factor complex

sp|P28362|MSX2_CHICK
Homeobox protein MSX-2
Search

MSX2

0.95	Muscle segment homeobox 3

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0051253	negative regulation of RNA metabolic process
0.50	GO:0010558	negative regulation of macromolecule biosynthetic process
0.50	GO:0031327	negative regulation of cellular biosynthetic process
0.50	GO:2001055	positive regulation of mesenchymal cell apoptotic process
0.49	GO:0090427	activation of meiosis
0.49	GO:0035880	embryonic nail plate morphogenesis
0.49	GO:0060364	frontal suture morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.46	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.45	GO:0044212	transcription regulatory region DNA binding
0.43	GO:0003712	transcription cofactor activity
0.43	GO:0003690	double-stranded DNA binding
0.42	GO:0008134	transcription factor binding
0.36	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0002039	p53 binding
0.35	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.48	GO:0005829	cytosol
0.48	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.33	GO:0005667	transcription factor complex

sp|P28497|CAZA2_CHICK
F-actin-capping protein subunit alpha-2
Search

CAPZA2

0.95	Capping actin protein of muscle Z-line alpha subunit 2

0.84	GO:0051016	barbed-end actin filament capping
0.38	GO:0034329	cell junction assembly
0.36	GO:0050878	regulation of body fluid levels
0.35	GO:0070495	negative regulation of thrombin-activated receptor signaling pathway
0.35	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity
0.35	GO:1901299	negative regulation of hydrogen peroxide-mediated programmed cell death
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0001886	endothelial cell morphogenesis
0.35	GO:2001028	positive regulation of endothelial cell chemotaxis
0.35	GO:0051497	negative regulation of stress fiber assembly

0.73	GO:0003779	actin binding
0.38	GO:0045296	cadherin binding
0.34	GO:0019903	protein phosphatase binding
0.34	GO:0004713	protein tyrosine kinase activity
0.34	GO:0042802	identical protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.84	GO:0008290	F-actin capping protein complex
0.52	GO:0005903	brush border
0.50	GO:0030863	cortical cytoskeleton
0.38	GO:0071203	WASH complex
0.36	GO:0030018	Z disc
0.36	GO:0070062	extracellular exosome
0.35	GO:0009925	basal plasma membrane
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.34

EC:2.7.10

GO:0004713

sp|P28568|GTR3_CHICK
Solute carrier family 2, facilitated glucose transporter member 3
Search

SLC2A3

0.77	Glucose transporter

0.66	GO:1904659	glucose transmembrane transport
0.52	GO:0070837	dehydroascorbic acid transport
0.36	GO:0046323	glucose import
0.35	GO:0007275	multicellular organism development
0.35	GO:0043066	negative regulation of apoptotic process
0.35	GO:1904016	response to Thyroglobulin triiodothyronine
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0030154	cell differentiation
0.34	GO:0019852	L-ascorbic acid metabolic process
0.34	GO:0003158	endothelium development

0.67	GO:0005355	glucose transmembrane transporter activity
0.52	GO:0033300	dehydroascorbic acid transmembrane transporter activity
0.43	GO:0005536	glucose binding
0.35	GO:0033222	xylose binding
0.35	GO:0016936	galactoside binding
0.34	GO:0019900	kinase binding

0.50	GO:0002080	acrosomal membrane
0.40	GO:0005886	plasma membrane
0.37	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0035579	specific granule membrane
0.35	GO:0070821	tertiary granule membrane
0.34	GO:0030672	synaptic vesicle membrane
0.34	GO:0045121	membrane raft
0.33	GO:0005634	nucleus

sp|P28673|NPY_CHICK
Pro-neuropeptide Y
Search

NPY

0.95	Prepro-neuropeptide Y

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0007218	neuropeptide signaling pathway
0.55	GO:0021954	central nervous system neuron development
0.55	GO:0021987	cerebral cortex development
0.54	GO:0008217	regulation of blood pressure
0.52	GO:0031175	neuron projection development
0.49	GO:0032098	regulation of appetite
0.48	GO:0007631	feeding behavior
0.44	GO:0007267	cell-cell signaling
0.43	GO:0032097	positive regulation of response to food

0.79	GO:0005179	hormone activity
0.55	GO:0001664	G-protein coupled receptor binding
0.35	GO:0005246	calcium channel regulator activity
0.34	GO:0004930	G-protein coupled receptor activity

0.66	GO:0005576	extracellular region
0.49	GO:0005794	Golgi apparatus
0.35	GO:0043204	perikaryon
0.35	GO:0043195	terminal bouton
0.34	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016020	membrane

sp|P28675|PGS2_CHICK
Decorin
Search

DCN

0.97

Decorin

0.59	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway
0.59	GO:0050654	chondroitin sulfate proteoglycan metabolic process
0.59	GO:0051901	positive regulation of mitochondrial depolarization
0.58	GO:0090141	positive regulation of mitochondrial fission
0.57	GO:0010596	negative regulation of endothelial cell migration
0.56	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.56	GO:0016239	positive regulation of macroautophagy
0.55	GO:0016525	negative regulation of angiogenesis
0.55	GO:0018149	peptide cross-linking
0.55	GO:1903510	mucopolysaccharide metabolic process

0.83	GO:0005518	collagen binding
0.55	GO:0050840	extracellular matrix binding
0.51	GO:0005539	glycosaminoglycan binding
0.47	GO:0004860	protein kinase inhibitor activity
0.40	GO:0047485	protein N-terminus binding
0.35	GO:0098633	collagen fibril binding
0.34	GO:0042803	protein homodimerization activity
0.33	GO:0003723	RNA binding

0.76	GO:0005578	proteinaceous extracellular matrix
0.51	GO:0005615	extracellular space
0.42	GO:0098647	collagen beaded filament
0.38	GO:0005581	collagen trimer
0.36	GO:0005737	cytoplasm
0.33	GO:0012505	endomembrane system
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part
0.32	GO:0043231	intracellular membrane-bounded organelle

sp|P28682|OPSB_CHICK
Blue-sensitive opsin
Search

SWS2

0.81	Blue-sensitive cone opsin

0.79	GO:0007602	phototransduction
0.78	GO:0007601	visual perception
0.74	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.57	GO:0016038	absorption of visible light
0.39	GO:0009584	detection of visible light
0.34	GO:0009785	blue light signaling pathway

0.79	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.43	GO:0001750	photoreceptor outer segment
0.30	GO:0044425	membrane part

sp|P28683|OPSG_CHICK
Green-sensitive opsin
Search

RH2

0.57	Green-sensitive opsin

0.79	GO:0007602	phototransduction
0.78	GO:0007601	visual perception
0.75	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.62	GO:0016038	absorption of visible light
0.39	GO:0009584	detection of visible light
0.34	GO:0070207	protein homotrimerization
0.34	GO:0071482	cellular response to light stimulus

0.79	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.35	GO:0005502	11-cis retinal binding
0.34	GO:0042803	protein homodimerization activity

0.41	GO:0001750	photoreceptor outer segment
0.34	GO:0060170	ciliary membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P28684|OPSV_CHICK
Violet-sensitive opsin
Search

SWS1

0.84	Short wavelength-sensitive opsin

0.78	GO:0007602	phototransduction
0.77	GO:0007601	visual perception
0.73	GO:0018298	protein-chromophore linkage
0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0016038	absorption of visible light
0.41	GO:0009584	detection of visible light
0.34	GO:0001523	retinoid metabolic process

0.78	GO:0009881	photoreceptor activity
0.70	GO:0004930	G-protein coupled receptor activity

0.50	GO:0001750	photoreceptor outer segment
0.35	GO:0060170	ciliary membrane
0.33	GO:0005887	integral component of plasma membrane

sp|P28685|CNTN2_CHICK
Contactin-2
Search

CNTN2

0.97	LOW QUALITY PROTEIN: contactin-2

0.78	GO:0031175	neuron projection development
0.60	GO:0071206	establishment of protein localization to juxtaparanode region of axon
0.60	GO:0045163	clustering of voltage-gated potassium channels
0.59	GO:0060168	positive regulation of adenosine receptor signaling pathway
0.59	GO:0021853	cerebral cortex GABAergic interneuron migration
0.59	GO:0031133	regulation of axon diameter
0.58	GO:0097090	presynaptic membrane organization
0.57	GO:0022010	central nervous system myelination
0.57	GO:0010954	positive regulation of protein processing
0.57	GO:0048710	regulation of astrocyte differentiation

0.55	GO:0043621	protein self-association
0.49	GO:0030246	carbohydrate binding
0.35	GO:0050839	cell adhesion molecule binding
0.34	GO:0042802	identical protein binding

0.58	GO:0044224	juxtaparanode region of axon
0.58	GO:0033268	node of Ranvier
0.54	GO:0043209	myelin sheath
0.53	GO:0043025	neuronal cell body
0.52	GO:0008076	voltage-gated potassium channel complex
0.51	GO:0009986	cell surface
0.39	GO:0031225	anchored component of membrane
0.36	GO:0045202	synapse

sp|P28686|NOV_CHICK
Protein NOV
Search

NOV

0.97	Nephroblastoma overexpressed

0.79	GO:0001558	regulation of cell growth
0.78	GO:0048659	smooth muscle cell proliferation
0.78	GO:0090027	negative regulation of monocyte chemotaxis
0.78	GO:0060392	negative regulation of SMAD protein import into nucleus
0.77	GO:0071603	endothelial cell-cell adhesion
0.77	GO:1990523	bone regeneration
0.76	GO:1902731	negative regulation of chondrocyte proliferation
0.76	GO:0044342	type B pancreatic cell proliferation
0.76	GO:0014909	smooth muscle cell migration
0.76	GO:0061484	hematopoietic stem cell homeostasis

0.82	GO:0005520	insulin-like growth factor binding
0.74	GO:0005178	integrin binding
0.72	GO:0005112	Notch binding
0.55	GO:0008201	heparin binding

0.68	GO:0005921	gap junction
0.66	GO:0005576	extracellular region
0.49	GO:0043231	intracellular membrane-bounded organelle
0.44	GO:0005737	cytoplasm
0.38	GO:0043025	neuronal cell body
0.38	GO:0030425	dendrite
0.38	GO:0030424	axon

sp|P28687|SPCS3_CHICK
Signal peptidase complex subunit 3
Search

SPCS3

0.93	Signal peptidase complex subunit 3

0.80	GO:0006465	signal peptide processing
0.44	GO:0045047	protein targeting to ER
0.36	GO:0045444	fat cell differentiation

0.61

GO:0008233

peptidase activity

0.82	GO:0005787	signal peptidase complex
0.36	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.61

GO:0008233

sp|P28693|EPHB2_CHICK
Ephrin type-B receptor 2
Search

EPHB2

0.91	EPH receptor B2

0.84	GO:0048013	ephrin receptor signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.71	GO:0106028	neuron projection retraction
0.71	GO:0099557	trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission
0.71	GO:1904782	negative regulation of NMDA glutamate receptor activity
0.70	GO:1904783	positive regulation of NMDA glutamate receptor activity
0.69	GO:0048170	positive regulation of long-term neuronal synaptic plasticity
0.69	GO:0051389	inactivation of MAPKK activity
0.68	GO:0031915	positive regulation of synaptic plasticity
0.68	GO:0021631	optic nerve morphogenesis

0.85	GO:0005003	ephrin receptor activity
0.68	GO:0008046	axon guidance receptor activity
0.65	GO:0001540	amyloid-beta binding
0.57	GO:0042802	identical protein binding
0.56	GO:0005102	receptor binding
0.56	GO:0044877	macromolecular complex binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding

0.66	GO:0005887	integral component of plasma membrane
0.61	GO:0043025	neuronal cell body
0.61	GO:0030425	dendrite
0.61	GO:0030424	axon
0.48	GO:0005634	nucleus

sp|P28701|RXRG_CHICK
Retinoic acid receptor RXR-gamma
Search

RXRG

0.92	Retinoic acid receptor RXR-gamma

0.77	GO:0043401	steroid hormone mediated signaling pathway
0.57	GO:0097659	nucleic acid-templated transcription
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.53	GO:0010467	gene expression
0.52	GO:0034645	cellular macromolecule biosynthetic process
0.50	GO:0048384	retinoic acid receptor signaling pathway
0.48	GO:0051289	protein homotetramerization
0.45	GO:1902680	positive regulation of RNA biosynthetic process

0.78	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.60	GO:0003700	DNA binding transcription factor activity
0.47	GO:0044212	transcription regulatory region DNA binding
0.45	GO:0003690	double-stranded DNA binding
0.38	GO:0035257	nuclear hormone receptor binding
0.38	GO:0050692	DBD domain binding
0.38	GO:0050693	LBD domain binding
0.38	GO:0001972	retinoic acid binding

0.60	GO:0005634	nucleus
0.39	GO:0005667	transcription factor complex
0.36	GO:0043235	receptor complex
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0000785	chromatin
0.35	GO:0030424	axon

sp|P29203|PYY_CHICK
Peptide YY-like
Search

0.62	Skin peptide tyrosine-tyrosine

0.76	GO:0010469	regulation of receptor activity
0.69	GO:0007218	neuropeptide signaling pathway
0.52	GO:0021954	central nervous system neuron development
0.51	GO:0021987	cerebral cortex development
0.51	GO:0008217	regulation of blood pressure
0.49	GO:0032098	regulation of appetite
0.49	GO:0031175	neuron projection development
0.48	GO:0007631	feeding behavior
0.45	GO:0007267	cell-cell signaling
0.41	GO:0032097	positive regulation of response to food

0.79	GO:0005179	hormone activity
0.55	GO:0001664	G-protein coupled receptor binding
0.34	GO:0005246	calcium channel regulator activity
0.33	GO:0004930	G-protein coupled receptor activity

0.66	GO:0005576	extracellular region
0.46	GO:0005794	Golgi apparatus
0.34	GO:0043204	perikaryon
0.34	GO:0043195	terminal bouton
0.34	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016020	membrane

sp|P29318|EPHA3_CHICK
Ephrin type-A receptor 3
Search

EPHA3

0.91	Eph receptor A3, like

0.84	GO:0048013	ephrin receptor signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.67	GO:0071300	cellular response to retinoic acid
0.67	GO:0045806	negative regulation of endocytosis
0.67	GO:0051893	regulation of focal adhesion assembly
0.66	GO:1903078	positive regulation of protein localization to plasma membrane
0.65	GO:0010976	positive regulation of neuron projection development
0.63	GO:0070507	regulation of microtubule cytoskeleton organization
0.61	GO:0032956	regulation of actin cytoskeleton organization
0.59	GO:0043087	regulation of GTPase activity

0.85	GO:0005003	ephrin receptor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.65	GO:0005887	integral component of plasma membrane
0.63	GO:0005769	early endosome

sp|P29332|CCNB2_CHICK
G2/mitotic-specific cyclin-B2
Search

CCNB2

0.97	Mitotic specific cyclin B2

0.54	GO:0043029	T cell homeostasis
0.53	GO:0048538	thymus development
0.51	GO:0001701	in utero embryonic development
0.50	GO:0040007	growth
0.43	GO:2000775	histone H3-S10 phosphorylation involved in chromosome condensation
0.43	GO:0031662	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle
0.43	GO:1905448	positive regulation of mitochondrial ATP synthesis coupled electron transport
0.42	GO:0007049	cell cycle
0.42	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore
0.41	GO:0048146	positive regulation of fibroblast proliferation

0.53	GO:0045296	cadherin binding
0.42	GO:0005113	patched binding
0.41	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity
0.40	GO:0044389	ubiquitin-like protein ligase binding
0.40	GO:0019901	protein kinase binding
0.37	GO:0016301	kinase activity
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.34	GO:0060089	molecular transducer activity
0.34	GO:0016874	ligase activity
0.34	GO:0140096	catalytic activity, acting on a protein

0.61	GO:0005634	nucleus
0.53	GO:0005813	centrosome
0.49	GO:0005829	cytosol
0.43	GO:0097125	cyclin B1-CDK1 complex
0.40	GO:0000940	condensed chromosome outer kinetochore
0.40	GO:0000922	spindle pole
0.39	GO:0005759	mitochondrial matrix
0.30	GO:0016020	membrane

0.34

GO:0016773

sp|P29415|CXA3_CHICK
Gap junction alpha-3 protein
Search

GJA3

0.55	Gap junction alpha-3 protein

0.75	GO:0007601	visual perception
0.60	GO:0007154	cell communication
0.53	GO:0055085	transmembrane transport
0.40	GO:0031444	slow-twitch skeletal muscle fiber contraction
0.36	GO:0001654	eye development
0.36	GO:0003161	cardiac conduction system development
0.36	GO:0055008	cardiac muscle tissue morphogenesis
0.35	GO:0048563	post-embryonic animal organ morphogenesis
0.35	GO:0008016	regulation of heart contraction
0.35	GO:0090596	sensory organ morphogenesis

0.85

GO:0005243

gap junction channel activity

0.84	GO:0005922	connexin complex
0.30	GO:0016021	integral component of membrane

sp|P29616|MYSC_CHICK
Myosin heavy chain, cardiac muscle isoform (Fragment)
Search

0.64	Myosin heavy chain 7

0.73	GO:0007018	microtubule-based movement
0.49	GO:0030049	muscle filament sliding
0.49	GO:0048738	cardiac muscle tissue development
0.49	GO:0060047	heart contraction
0.49	GO:0007512	adult heart development
0.49	GO:0003299	muscle hypertrophy in response to stress
0.49	GO:0014887	cardiac muscle adaptation
0.48	GO:0061061	muscle structure development
0.48	GO:0003300	cardiac muscle hypertrophy
0.48	GO:0003205	cardiac chamber development

0.74	GO:0051015	actin filament binding
0.74	GO:0003777	microtubule motor activity
0.73	GO:0008017	microtubule binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.49	GO:0030898	actin-dependent ATPase activity
0.48	GO:0000146	microfilament motor activity
0.41	GO:0005516	calmodulin binding

0.77	GO:0016459	myosin complex
0.50	GO:0030016	myofibril
0.47	GO:0044449	contractile fiber part
0.47	GO:0097517	contractile actin filament bundle
0.47	GO:0042641	actomyosin
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.33

EC:3.4.23

GO:0004190

sp|P30352|SRSF2_CHICK
Serine/arginine-rich splicing factor 2
Search

SRSF2

0.93	Serine and arginine rich splicing factor 2

0.77	GO:0043484	regulation of RNA splicing
0.46	GO:0050684	regulation of mRNA processing
0.41	GO:0033197	response to vitamin E
0.40	GO:0008380	RNA splicing
0.39	GO:0006397	mRNA processing
0.38	GO:0000278	mitotic cell cycle
0.35	GO:0006369	termination of RNA polymerase II transcription
0.35	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0031123	RNA 3'-end processing
0.34	GO:0051028	mRNA transport

0.59	GO:0003723	RNA binding
0.40	GO:0005080	protein kinase C binding
0.35	GO:0003714	transcription corepressor activity
0.33	GO:0004623	phospholipase A2 activity

0.50	GO:0016607	nuclear speck
0.46	GO:0005681	spliceosomal complex
0.45	GO:0005829	cytosol
0.41	GO:0035061	interchromatin granule
0.37	GO:0016605	PML body
0.36	GO:0070062	extracellular exosome
0.33	GO:0000785	chromatin
0.33	GO:0019013	viral nucleocapsid
0.30	GO:0016020	membrane

0.33

EC:3.1.1.4

GO:0004623

sp|P30370|RABP2_CHICK
Cellular retinoic acid-binding protein 2 (Fragment)
Search

0.79	Cellular retinoic acid-binding protein 2 (Fragment)

0.72	GO:0042573	retinoic acid metabolic process
0.72	GO:0048385	regulation of retinoic acid receptor signaling pathway
0.65	GO:0042363	fat-soluble vitamin catabolic process
0.65	GO:0016103	diterpenoid catabolic process
0.56	GO:0048672	positive regulation of collateral sprouting
0.55	GO:0035115	embryonic forelimb morphogenesis
0.55	GO:0072329	monocarboxylic acid catabolic process
0.46	GO:0021575	hindbrain morphogenesis
0.35	GO:0016102	diterpenoid biosynthetic process
0.34	GO:0008544	epidermis development

0.81	GO:0001972	retinoic acid binding
0.45	GO:0019841	retinol binding
0.44	GO:0016918	retinal binding
0.36	GO:0019215	intermediate filament binding
0.34	GO:0030332	cyclin binding
0.34	GO:0005198	structural molecule activity

0.50	GO:0005634	nucleus
0.47	GO:0005829	cytosol
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.37	GO:0005783	endoplasmic reticulum
0.36	GO:0070062	extracellular exosome
0.35	GO:0045111	intermediate filament cytoskeleton
0.35	GO:0099512	supramolecular fiber

sp|P30371|TGFB2_CHICK
Transforming growth factor beta-2
Search

TGFB2

0.85	Transforming growth factor beta-2

0.80	GO:0016049	cell growth
0.74	GO:0010469	regulation of receptor activity
0.66	GO:0051795	positive regulation of timing of catagen
0.66	GO:0045726	positive regulation of integrin biosynthetic process
0.66	GO:0010693	negative regulation of alkaline phosphatase activity
0.66	GO:0051891	positive regulation of cardioblast differentiation
0.65	GO:0010936	negative regulation of macrophage cytokine production
0.65	GO:0032909	regulation of transforming growth factor beta2 production
0.64	GO:0060389	pathway-restricted SMAD protein phosphorylation
0.64	GO:0060038	cardiac muscle cell proliferation

0.85	GO:0005160	transforming growth factor beta receptor binding
0.76	GO:0008083	growth factor activity
0.62	GO:0001540	amyloid-beta binding
0.56	GO:0042803	protein homodimerization activity
0.45	GO:0005125	cytokine activity
0.35	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.34	GO:0046982	protein heterodimerization activity
0.34	GO:0003823	antigen binding
0.34	GO:0043539	protein serine/threonine kinase activator activity
0.33	GO:0019899	enzyme binding

0.72	GO:0005615	extracellular space
0.56	GO:0031012	extracellular matrix
0.41	GO:0043025	neuronal cell body
0.40	GO:0030424	axon
0.36	GO:0031093	platelet alpha granule lumen
0.34	GO:0005768	endosome
0.34	GO:0005902	microvillus
0.33	GO:0009986	cell surface
0.32	GO:0005634	nucleus

0.35

GO:0004702

sp|P30372|ACM2_CHICK
Muscarinic acetylcholine receptor M2
Search

CHRM2

0.81	Muscarinic acetylcholine receptor

0.85	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.77	GO:0008016	regulation of heart contraction
0.53	GO:0040012	regulation of locomotion
0.52	GO:0009615	response to virus
0.49	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.48	GO:0007271	synaptic transmission, cholinergic
0.47	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.47	GO:0006940	regulation of smooth muscle contraction
0.42	GO:1903523	negative regulation of blood circulation
0.39	GO:0046541	saliva secretion

0.85	GO:0016907	G-protein coupled acetylcholine receptor activity
0.59	GO:1990763	arrestin family protein binding
0.34	GO:0008144	drug binding

0.79	GO:0045211	postsynaptic membrane
0.75	GO:0030054	cell junction
0.67	GO:0005887	integral component of plasma membrane
0.40	GO:0032280	symmetric synapse
0.39	GO:0043679	axon terminus
0.39	GO:0032279	asymmetric synapse
0.38	GO:0043025	neuronal cell body
0.38	GO:0030425	dendrite
0.34	GO:0030665	clathrin-coated vesicle membrane

sp|P30373|CKR1_CHICK
Zinc finger protein CKR1
Search

0.50	Zinc finger protein 84

0.49	GO:1903506	regulation of nucleic acid-templated transcription
0.49	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.49	GO:0010468	regulation of gene expression
0.37	GO:0043065	positive regulation of apoptotic process
0.36	GO:1902679	negative regulation of RNA biosynthetic process
0.36	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.46	GO:0046872	metal ion binding
0.39	GO:0003700	DNA binding transcription factor activity
0.37	GO:0042802	identical protein binding

0.41	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

sp|P30374|RSFR_CHICK
Ribonuclease homolog
Search

RNASE4

0.89	Leukocyte ribonuclease A-2

0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.60	GO:0050830	defense response to Gram-positive bacterium
0.59	GO:0050829	defense response to Gram-negative bacterium
0.58	GO:0001525	angiogenesis
0.48	GO:0016070	RNA metabolic process
0.43	GO:0009267	cellular response to starvation

0.66	GO:0004519	endonuclease activity
0.59	GO:0004540	ribonuclease activity
0.51	GO:0003676	nucleic acid binding

0.55	GO:0005576	extracellular region
0.42	GO:0005737	cytoplasm
0.38	GO:0031982	vesicle

sp|P30802|GALA_CHICK
Galanin
Search

GAL

0.77

Galanin

0.76	GO:0010469	regulation of receptor activity
0.58	GO:1902891	negative regulation of root hair elongation
0.57	GO:1902608	positive regulation of large conductance calcium-activated potassium channel activity
0.56	GO:0051795	positive regulation of timing of catagen
0.56	GO:0051464	positive regulation of cortisol secretion
0.56	GO:0007218	neuropeptide signaling pathway
0.55	GO:0010737	protein kinase A signaling
0.52	GO:0019933	cAMP-mediated signaling
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.48	GO:0007399	nervous system development

0.79	GO:0005179	hormone activity
0.60	GO:0031763	galanin receptor binding
0.57	GO:0004966	galanin receptor activity

0.66	GO:0005576	extracellular region
0.51	GO:0043025	neuronal cell body
0.46	GO:0030141	secretory granule
0.38	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

sp|P30985|HTF4_CHICK
Transcription factor 12 (Fragment)
Search

TCF12

0.93	Transcription factor 12

0.56	GO:0045666	positive regulation of neuron differentiation
0.53	GO:0045944	positive regulation of transcription by RNA polymerase II
0.51	GO:0006366	transcription by RNA polymerase II
0.33	GO:1902036	regulation of hematopoietic stem cell differentiation
0.33	GO:0007517	muscle organ development
0.32	GO:0006955	immune response

0.67	GO:0046983	protein dimerization activity
0.59	GO:0043425	bHLH transcription factor binding
0.59	GO:0070888	E-box binding
0.55	GO:0046332	SMAD binding
0.54	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0042802	identical protein binding
0.41	GO:0071837	HMG box domain binding
0.41	GO:0035497	cAMP response element binding
0.33	GO:0035326	enhancer binding

0.54	GO:0016607	nuclear speck
0.53	GO:0005667	transcription factor complex
0.51	GO:0000790	nuclear chromatin
0.39	GO:0005737	cytoplasm

sp|P30997|CTNA2_CHICK
Catenin alpha-2
Search

CTNNA2

0.91	Catenin (cadherin-associated protein), alpha 2

0.73	GO:0048854	brain morphogenesis
0.68	GO:0007155	cell adhesion
0.53	GO:2001045	negative regulation of integrin-mediated signaling pathway
0.53	GO:0071681	cellular response to indole-3-methanol
0.52	GO:0007015	actin filament organization
0.51	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.51	GO:0007406	negative regulation of neuroblast proliferation
0.51	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.50	GO:0045880	positive regulation of smoothened signaling pathway
0.50	GO:0043297	apical junction assembly

0.77	GO:0045296	cadherin binding
0.74	GO:0051015	actin filament binding
0.56	GO:0008013	beta-catenin binding
0.55	GO:0005198	structural molecule activity
0.52	GO:0045295	gamma-catenin binding
0.52	GO:0017166	vinculin binding
0.49	GO:0042802	identical protein binding
0.46	GO:0046982	protein heterodimerization activity
0.33	GO:0003723	RNA binding

0.75	GO:0005913	cell-cell adherens junction
0.65	GO:0015629	actin cytoskeleton
0.52	GO:0030027	lamellipodium
0.52	GO:0016342	catenin complex
0.51	GO:0016600	flotillin complex
0.50	GO:0014704	intercalated disc
0.50	GO:0005829	cytosol
0.48	GO:0043296	apical junction complex
0.45	GO:0005794	Golgi apparatus
0.45	GO:0030424	axon

sp|P31043|CD28_CHICK
T-cell-specific surface glycoprotein CD28 homolog
Search

CD28

0.97	T-cell-specific surface glycoprotein CD28

0.72	GO:0006955	immune response
0.62	GO:0045086	positive regulation of interleukin-2 biosynthetic process
0.59	GO:0042102	positive regulation of T cell proliferation
0.58	GO:0045840	positive regulation of mitotic nuclear division
0.58	GO:0045066	regulatory T cell differentiation
0.58	GO:0032753	positive regulation of interleukin-4 production
0.57	GO:0032733	positive regulation of interleukin-10 production
0.56	GO:0048304	positive regulation of isotype switching to IgG isotypes
0.56	GO:0002863	positive regulation of inflammatory response to antigenic stimulus
0.56	GO:0045060	negative thymic T cell selection

0.55	GO:0005070	SH3/SH2 adaptor activity
0.54	GO:0002020	protease binding
0.51	GO:0019901	protein kinase binding
0.37	GO:0015026	coreceptor activity
0.35	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0042802	identical protein binding
0.33	GO:0046983	protein dimerization activity

0.54	GO:0001772	immunological synapse
0.53	GO:0009897	external side of plasma membrane
0.53	GO:0098636	protein complex involved in cell adhesion
0.44	GO:0044214	spanning component of plasma membrane
0.34	GO:0045121	membrane raft
0.33	GO:0005829	cytosol

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

sp|P31258|HXA11_CHICK
Homeobox protein Hox-A11
Search

HOXA11

0.97	Homeobox protein Hox-A11

0.56	GO:0007501	mesodermal cell fate specification
0.56	GO:0032332	positive regulation of chondrocyte differentiation
0.55	GO:0060272	embryonic skeletal joint morphogenesis
0.55	GO:0060351	cartilage development involved in endochondral bone morphogenesis
0.55	GO:0060065	uterus development
0.55	GO:0001759	organ induction
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0001658	branching involved in ureteric bud morphogenesis
0.54	GO:0035115	embryonic forelimb morphogenesis

0.62	GO:0043565	sequence-specific DNA binding
0.33	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.48	GO:0032993	protein-DNA complex
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part

sp|P31259|HXB1_CHICK
Homeobox protein Hox-B1
Search

0.81	Homeobox protein Hox-B1

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0021598	abducens nerve morphogenesis
0.55	GO:0060876	semicircular canal formation
0.54	GO:0042473	outer ear morphogenesis
0.54	GO:0007634	optokinetic behavior
0.54	GO:0021603	cranial nerve formation
0.54	GO:0048702	embryonic neurocranium morphogenesis
0.53	GO:0090103	cochlea morphogenesis

0.65	GO:0043565	sequence-specific DNA binding
0.47	GO:0042802	identical protein binding
0.38	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.37	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0001012	RNA polymerase II regulatory region DNA binding
0.37	GO:0019904	protein domain specific binding
0.36	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part

sp|P31335|PUR9_CHICK
Bifunctional purine biosynthesis protein PURH
Search

ATIC

0.75	Aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase

0.66

GO:0006164

purine nucleotide biosynthetic process

0.79	GO:0004643	phosphoribosylaminoimidazolecarboxamide formyltransferase activity
0.79	GO:0003937	IMP cyclohydrolase activity
0.63	GO:0045296	cadherin binding
0.59	GO:0042803	protein homodimerization activity

0.54	GO:0005829	cytosol
0.49	GO:0005739	mitochondrion
0.46	GO:0005886	plasma membrane

0.79

EC:2.1.2.3

GO:0004643

sp|P31395|STMN1_CHICK
Stathmin
Search

STMN1

0.86

Stathmin

0.84	GO:0031110	regulation of microtubule polymerization or depolymerization
0.56	GO:0007019	microtubule depolymerization
0.55	GO:0070495	negative regulation of thrombin-activated receptor signaling pathway
0.54	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity
0.54	GO:0032272	negative regulation of protein polymerization
0.54	GO:1902904	negative regulation of supramolecular fiber organization
0.53	GO:0048012	hepatocyte growth factor receptor signaling pathway
0.53	GO:0051494	negative regulation of cytoskeleton organization
0.53	GO:0048699	generation of neurons
0.53	GO:0061436	establishment of skin barrier

0.50	GO:0015631	tubulin binding
0.44	GO:0048306	calcium-dependent protein binding
0.37	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity
0.33	GO:0004871	signal transducer activity

0.50	GO:0043005	neuron projection
0.45	GO:0005829	cytosol
0.43	GO:0030427	site of polarized growth
0.43	GO:0030027	lamellipodium
0.43	GO:0043025	neuronal cell body
0.42	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0120038	plasma membrane bounded cell projection part
0.40	GO:0005874	microtubule
0.37	GO:0031982	vesicle
0.36	GO:0043230	extracellular organelle

0.37

EC:3.1.1.47

GO:0003847

sp|P31696|AGRIN_CHICK
Agrin
Search

AGRN

0.71	Agrin isoform B

0.76	GO:0043113	receptor clustering
0.75	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.48	GO:0007422	peripheral nervous system development
0.47	GO:0009952	anterior/posterior pattern specification
0.47	GO:0048666	neuron development
0.46	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.46	GO:0000904	cell morphogenesis involved in differentiation
0.46	GO:0007417	central nervous system development
0.45	GO:0120036	plasma membrane bounded cell projection organization
0.44	GO:0006898	receptor-mediated endocytosis

0.77	GO:0043236	laminin binding
0.68	GO:0005509	calcium ion binding
0.47	GO:0005044	scavenger receptor activity
0.38	GO:0035374	chondroitin sulfate binding
0.38	GO:0033691	sialic acid binding
0.37	GO:0002162	dystroglycan binding
0.37	GO:0043395	heparan sulfate proteoglycan binding
0.36	GO:0005200	structural constituent of cytoskeleton
0.31	GO:0004725	protein tyrosine phosphatase activity
0.30	GO:0004871	signal transducer activity

0.51	GO:0005886	plasma membrane
0.48	GO:0005605	basal lamina
0.42	GO:0005829	cytosol
0.37	GO:0043202	lysosomal lumen
0.37	GO:0005796	Golgi lumen
0.36	GO:0070062	extracellular exosome
0.36	GO:0045202	synapse
0.36	GO:0030054	cell junction
0.30	GO:0097458	neuron part
0.30	GO:0120025	plasma membrane bounded cell projection

0.31

EC:3.1.3.48

GO:0004725

sp|P32017|CO9A3_CHICK
Collagen alpha-3(IX) chain
Search

COL9A3

0.96	Collagen type IX alpha 3 chain

0.62	GO:0008584	male gonad development
0.62	GO:0008585	female gonad development
0.43	GO:0072577	endothelial cell apoptotic process
0.42	GO:0032836	glomerular basement membrane development
0.42	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.41	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.41	GO:0016525	negative regulation of angiogenesis
0.40	GO:0008283	cell proliferation
0.38	GO:0007155	cell adhesion
0.35	GO:0030574	collagen catabolic process

0.53	GO:0005201	extracellular matrix structural constituent
0.41	GO:0005178	integrin binding
0.35	GO:0008191	metalloendopeptidase inhibitor activity
0.32	GO:0004872	receptor activity

0.77	GO:0005581	collagen trimer
0.51	GO:0031012	extracellular matrix
0.39	GO:0005783	endoplasmic reticulum
0.39	GO:0099080	supramolecular complex
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P32018|COEA1_CHICK
Collagen alpha-1(XIV) chain
Search

0.81	Collagen, type XIV, alpha 1

0.49

GO:0070831

basement membrane assembly

0.74	GO:0005581	collagen trimer
0.47	GO:0005604	basement membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P32046|RL37A_CHICK
60S ribosomal protein L37a
Search

RPL37A

0.81	Ribosomal protein L37a

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0000733	DNA strand renaturation
0.34	GO:0044265	cellular macromolecule catabolic process
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0034655	nucleobase-containing compound catabolic process
0.33	GO:0016071	mRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.36	GO:0046872	metal ion binding
0.35	GO:0036310	annealing helicase activity
0.34	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.34	GO:0070180	large ribosomal subunit rRNA binding
0.33	GO:0005515	protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.35	GO:0005925	focal adhesion
0.35	GO:0070062	extracellular exosome
0.35	GO:0044445	cytosolic part
0.33	GO:0005634	nucleus
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0036459

sp|P32250|LPAR6_CHICK
Lysophosphatidic acid receptor 6
Search

LPAR6

0.97	Oleoyl-L-alpha-lysophosphatidic acid receptor

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.51	GO:0035025	positive regulation of Rho protein signal transduction
0.48	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.46	GO:0001525	angiogenesis

0.71	GO:0004930	G-protein coupled receptor activity
0.42	GO:0035727	lysophosphatidic acid binding

0.43	GO:0005886	plasma membrane
0.42	GO:0043227	membrane-bounded organelle
0.41	GO:0043229	intracellular organelle
0.38	GO:0043233	organelle lumen
0.30	GO:0016021	integral component of membrane

sp|P32429|RL7A_CHICK
60S ribosomal protein L7a
Search

RPL7A

0.82	Ribosomal protein L7a

0.66	GO:0042254	ribosome biogenesis
0.43	GO:0016072	rRNA metabolic process
0.42	GO:0034470	ncRNA processing
0.40	GO:0043043	peptide biosynthetic process
0.39	GO:0044267	cellular protein metabolic process
0.38	GO:0009059	macromolecule biosynthetic process
0.36	GO:1904401	cellular response to Thyroid stimulating hormone
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.45	GO:0045296	cadherin binding
0.40	GO:0003723	RNA binding
0.33	GO:0003735	structural constituent of ribosome

0.61	GO:0030529	intracellular ribonucleoprotein complex
0.53	GO:0043232	intracellular non-membrane-bounded organelle
0.50	GO:0044444	cytoplasmic part
0.39	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P32760|PTN_CHICK
Pleiotrophin
Search

PTN

0.97	Pleiotrophin

0.76	GO:0010469	regulation of receptor activity
0.54	GO:0030282	bone mineralization
0.53	GO:0007611	learning or memory
0.52	GO:0008284	positive regulation of cell proliferation
0.44	GO:0007399	nervous system development
0.42	GO:0051781	positive regulation of cell division
0.41	GO:1904391	response to ciliary neurotrophic factor
0.41	GO:1904373	response to kainic acid
0.41	GO:0060322	head development
0.40	GO:1904395	positive regulation of skeletal muscle acetylcholine-gated channel clustering

0.78	GO:0008083	growth factor activity
0.58	GO:0035374	chondroitin sulfate binding
0.55	GO:0008201	heparin binding
0.50	GO:0019901	protein kinase binding
0.41	GO:1904399	heparan sulfate binding
0.40	GO:0035373	chondroitin sulfate proteoglycan binding
0.40	GO:0038085	vascular endothelial growth factor binding
0.34	GO:0004864	protein phosphatase inhibitor activity

0.49	GO:0005615	extracellular space
0.47	GO:0005783	endoplasmic reticulum
0.43	GO:0043234	protein complex
0.39	GO:0005604	basement membrane
0.39	GO:0031594	neuromuscular junction
0.38	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0009986	cell surface
0.30	GO:0016020	membrane

sp|P32882|TBB2_CHICK
Tubulin beta-2 chain
Search

0.57	Tubulin beta chain

0.71	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.52	GO:1902669	positive regulation of axon guidance
0.50	GO:0001764	neuron migration
0.37	GO:0031115	negative regulation of microtubule polymerization
0.33	GO:0070925	organelle assembly
0.33	GO:0022402	cell cycle process

0.77	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0046982	protein heterodimerization activity
0.35	GO:0005509	calcium ion binding
0.34	GO:0042288	MHC class I protein binding
0.34	GO:0003725	double-stranded RNA binding

0.73	GO:0005874	microtubule
0.46	GO:0005737	cytoplasm
0.36	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus
0.35	GO:0044297	cell body
0.35	GO:0033269	internode region of axon
0.34	GO:0036477	somatodendritic compartment
0.34	GO:0044441	ciliary part
0.34	GO:0031970	organelle envelope lumen

sp|P33005|KALM_CHICK
Anosmin-1
Search

ANOS1

0.94	Kallmann syndrome 1

0.74	GO:0010466	negative regulation of peptidase activity
0.43	GO:0097155	fasciculation of sensory neuron axon
0.43	GO:0048920	posterior lateral line neuromast primordium migration
0.43	GO:0097154	GABAergic neuron differentiation
0.42	GO:0071542	dopaminergic neuron differentiation
0.42	GO:0021772	olfactory bulb development
0.41	GO:0007411	axon guidance
0.38	GO:0052548	regulation of endopeptidase activity
0.37	GO:0007155	cell adhesion
0.35	GO:0008543	fibroblast growth factor receptor signaling pathway

0.75	GO:0030414	peptidase inhibitor activity
0.38	GO:0061135	endopeptidase regulator activity
0.35	GO:0008201	heparin binding
0.35	GO:0005201	extracellular matrix structural constituent
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.65	GO:0005576	extracellular region
0.37	GO:0009986	cell surface
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

sp|P33094|SMS_CHICK
Somatostatin
Search

SST

0.97	Preprosomatostatin I

0.76	GO:0010469	regulation of receptor activity
0.55	GO:0030334	regulation of cell migration
0.45	GO:0007267	cell-cell signaling
0.44	GO:0007166	cell surface receptor signaling pathway
0.39	GO:0010447	response to acidic pH
0.39	GO:0006972	hyperosmotic response
0.39	GO:0043200	response to amino acid
0.38	GO:0048545	response to steroid hormone
0.38	GO:0009408	response to heat
0.37	GO:0042493	response to drug

0.79	GO:0005179	hormone activity
0.34	GO:0031878	type 1 somatostatin receptor binding
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.39	GO:0043025	neuronal cell body
0.30	GO:0016020	membrane

sp|P33145|CADHK_CHICK
B-cadherin (Fragment)
Search

CDH1

0.95	Blastomere cadherin

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.57	GO:0071681	cellular response to indole-3-methanol
0.56	GO:0071285	cellular response to lithium ion
0.56	GO:0051050	positive regulation of transport
0.55	GO:0034332	adherens junction organization
0.54	GO:0060341	regulation of cellular localization
0.53	GO:0022408	negative regulation of cell-cell adhesion
0.53	GO:1904589	regulation of protein import
0.53	GO:0072659	protein localization to plasma membrane
0.53	GO:0031328	positive regulation of cellular biosynthetic process

0.70	GO:0005509	calcium ion binding
0.56	GO:0045295	gamma-catenin binding
0.56	GO:0032794	GTPase activating protein binding
0.56	GO:0030506	ankyrin binding
0.53	GO:0008013	beta-catenin binding
0.52	GO:0045296	cadherin binding
0.49	GO:0042802	identical protein binding
0.37	GO:0045294	alpha-catenin binding
0.36	GO:0019903	protein phosphatase binding
0.36	GO:0001965	G-protein alpha-subunit binding

0.58	GO:0005913	cell-cell adherens junction
0.56	GO:0016600	flotillin complex
0.56	GO:0016342	catenin complex
0.54	GO:0016328	lateral plasma membrane
0.53	GO:0030027	lamellipodium
0.52	GO:0030864	cortical actin cytoskeleton
0.52	GO:0043296	apical junction complex
0.51	GO:0005802	trans-Golgi network
0.51	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0009898	cytoplasmic side of plasma membrane

sp|P33150|CAD13_CHICK
Cadherin-13
Search

CDH13

0.97	LOW QUALITY PROTEIN: cadherin-13

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.57	GO:0055096	low-density lipoprotein particle mediated signaling
0.56	GO:0043616	keratinocyte proliferation
0.56	GO:0016601	Rac protein signal transduction
0.55	GO:0050927	positive regulation of positive chemotaxis
0.55	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.55	GO:0030032	lamellipodium assembly
0.55	GO:0048514	blood vessel morphogenesis
0.55	GO:0050850	positive regulation of calcium-mediated signaling
0.55	GO:0001954	positive regulation of cell-matrix adhesion

0.74	GO:0042803	protein homodimerization activity
0.70	GO:0005509	calcium ion binding
0.57	GO:0055100	adiponectin binding
0.56	GO:0030169	low-density lipoprotein particle binding
0.52	GO:0045296	cadherin binding

0.55	GO:0005886	plasma membrane
0.52	GO:0045121	membrane raft
0.50	GO:0043005	neuron projection
0.49	GO:0009986	cell surface
0.49	GO:0098552	side of membrane
0.49	GO:0031012	extracellular matrix
0.49	GO:0005615	extracellular space
0.40	GO:0031225	anchored component of membrane
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005925	focal adhesion

sp|P33717|IGF2_CHICK
Insulin-like growth factor II
Search

0.95	Preproinsulin-growth factor II

0.75	GO:0010469	regulation of receptor activity
0.52	GO:0046628	positive regulation of insulin receptor signaling pathway
0.52	GO:0042104	positive regulation of activated T cell proliferation
0.50	GO:0051897	positive regulation of protein kinase B signaling
0.50	GO:0045840	positive regulation of mitotic nuclear division
0.48	GO:0043410	positive regulation of MAPK cascade
0.42	GO:0048568	embryonic organ development
0.42	GO:0043009	chordate embryonic development
0.42	GO:0051781	positive regulation of cell division
0.41	GO:0032868	response to insulin

0.79	GO:0005179	hormone activity
0.78	GO:0008083	growth factor activity
0.53	GO:0005159	insulin-like growth factor receptor binding
0.51	GO:0005158	insulin receptor binding
0.37	GO:0043539	protein serine/threonine kinase activator activity

0.73	GO:0005615	extracellular space
0.35	GO:1903561	extracellular vesicle
0.35	GO:0031093	platelet alpha granule lumen
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P33879|AT1B3_CHICK
Sodium/potassium-transporting ATPase subunit beta-3
Search

ATP1B3

0.79	Sodium/potassium-transporting ATPase subunit beta

0.72	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.61	GO:1903288	positive regulation of potassium ion import
0.61	GO:1903278	positive regulation of sodium ion export across plasma membrane
0.60	GO:0006883	cellular sodium ion homeostasis
0.60	GO:0086009	membrane repolarization
0.59	GO:1901018	positive regulation of potassium ion transmembrane transporter activity
0.58	GO:0030007	cellular potassium ion homeostasis
0.57	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.57	GO:0140115	export across plasma membrane

0.58	GO:0051117	ATPase binding
0.58	GO:0005391	sodium:potassium-exchanging ATPase activity
0.56	GO:0001671	ATPase activator activity

0.84	GO:0005890	sodium:potassium-exchanging ATPase complex
0.47	GO:0016324	apical plasma membrane
0.40	GO:0042470	melanosome
0.38	GO:0005901	caveola
0.36	GO:0070062	extracellular exosome

0.58

GO:0005391

sp|P34065|PSB5_CHICK
Proteasome subunit beta type-5 (Fragment)
Search

PSMB5

0.53	Proteasome subunit beta type

0.71	GO:0051603	proteolysis involved in cellular protein catabolic process
0.67	GO:0043632	modification-dependent macromolecule catabolic process
0.46	GO:0006979	response to oxidative stress
0.35	GO:0080129	proteasome core complex assembly
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation

0.76	GO:0070003	threonine-type peptidase activity
0.64	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding

0.75	GO:0005839	proteasome core complex
0.59	GO:0005634	nucleus
0.49	GO:0005813	centrosome
0.48	GO:0005737	cytoplasm
0.45	GO:0031974	membrane-enclosed lumen
0.36	GO:0070062	extracellular exosome

sp|P34743|BTG1_CHICK
Protein BTG1
Search

BTG1

0.95	B-cell translocation protein 1, anti-proliferative

0.79	GO:0008285	negative regulation of cell proliferation
0.56	GO:2000271	positive regulation of fibroblast apoptotic process
0.55	GO:0045603	positive regulation of endothelial cell differentiation
0.54	GO:0045663	positive regulation of myoblast differentiation
0.52	GO:0045766	positive regulation of angiogenesis
0.48	GO:0021542	dentate gyrus development
0.48	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.47	GO:0035914	skeletal muscle cell differentiation
0.47	GO:0008306	associative learning
0.47	GO:0008213	protein alkylation

0.47	GO:0019899	enzyme binding
0.34	GO:0003712	transcription cofactor activity
0.34	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.43	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.34	GO:0070062	extracellular exosome

sp|P34822|DSL1_CHICK
Dorsalin-1
Search

GDF2

0.93	Growth differentiation factor 2

0.76	GO:0010469	regulation of receptor activity
0.65	GO:0060389	pathway-restricted SMAD protein phosphorylation
0.65	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.65	GO:0032924	activin receptor signaling pathway
0.64	GO:0010596	negative regulation of endothelial cell migration
0.64	GO:0061036	positive regulation of cartilage development
0.63	GO:0030509	BMP signaling pathway
0.62	GO:0030308	negative regulation of cell growth
0.59	GO:0072359	circulatory system development
0.59	GO:0008284	positive regulation of cell proliferation

0.78	GO:0008083	growth factor activity
0.53	GO:0031433	telethonin binding
0.52	GO:0033612	receptor serine/threonine kinase binding
0.51	GO:0005160	transforming growth factor beta receptor binding
0.49	GO:0005125	cytokine activity
0.48	GO:0005179	hormone activity
0.36	GO:0005501	retinoid binding
0.34	GO:0008236	serine-type peptidase activity

0.66	GO:0005576	extracellular region
0.50	GO:0030018	Z disc
0.47	GO:0009986	cell surface
0.35	GO:0031982	vesicle
0.30	GO:0016020	membrane

sp|P34904|GBRG4_CHICK
Gamma-aminobutyric acid receptor subunit gamma-4
Search

GABRG2

0.90	Gamma-aminobutyric acid type A receptor epsilon subunit

0.81	GO:0007214	gamma-aminobutyric acid signaling pathway
0.72	GO:0006821	chloride transport
0.60	GO:0034220	ion transmembrane transport
0.50	GO:0071420	cellular response to histamine
0.47	GO:0030534	adult behavior
0.46	GO:0007268	chemical synaptic transmission
0.46	GO:0009791	post-embryonic development
0.35	GO:0042493	response to drug

0.84	GO:0004890	GABA-A receptor activity
0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.47	GO:0005254	chloride channel activity
0.35	GO:0008503	benzodiazepine receptor activity
0.34	GO:0005515	protein binding

0.55	GO:0005886	plasma membrane
0.49	GO:1902711	GABA-A receptor complex
0.46	GO:0030424	axon
0.41	GO:0034707	chloride channel complex
0.40	GO:0098794	postsynapse
0.40	GO:0030054	cell junction
0.38	GO:0030425	dendrite
0.37	GO:0030659	cytoplasmic vesicle membrane
0.36	GO:0060077	inhibitory synapse
0.35	GO:0031252	cell leading edge

sp|P34963|NMU_CHICK
Neuromedin-U-25
Search

0.84	Neuromedin-U-25

0.85	GO:0006940	regulation of smooth muscle contraction
0.58	GO:2000821	regulation of grooming behavior
0.56	GO:0097009	energy homeostasis
0.55	GO:0060259	regulation of feeding behavior
0.55	GO:0001659	temperature homeostasis
0.52	GO:0007218	neuropeptide signaling pathway
0.46	GO:0048512	circadian behavior
0.39	GO:0010469	regulation of receptor activity

0.59	GO:0031839	type 1 neuromedin U receptor binding
0.59	GO:0031840	type 2 neuromedin U receptor binding
0.40	GO:0005179	hormone activity

0.37	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|P34996|P2RY1_CHICK
P2Y purinoceptor 1
Search

P2RY1

0.97	Purinergic receptor P2Y, G-protein coupled 1

0.86	GO:0090075	relaxation of muscle
0.85	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway
0.85	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.84	GO:0030168	platelet activation
0.68	GO:0043270	positive regulation of ion transport
0.65	GO:0071407	cellular response to organic cyclic compound
0.43	GO:0097746	regulation of blood vessel diameter
0.43	GO:0051047	positive regulation of secretion
0.42	GO:0070255	regulation of mucus secretion
0.42	GO:0051240	positive regulation of multicellular organismal process

0.85	GO:0045028	G-protein coupled purinergic nucleotide receptor activity
0.40	GO:0045032	ADP-activated adenosine receptor activity
0.40	GO:0031686	A1 adenosine receptor binding
0.40	GO:0045031	ATP-activated adenosine receptor activity
0.38	GO:0097110	scaffold protein binding
0.37	GO:0043531	ADP binding
0.37	GO:0046982	protein heterodimerization activity
0.34	GO:0005524	ATP binding

0.49	GO:0005886	plasma membrane
0.38	GO:0014069	postsynaptic density
0.38	GO:0030425	dendrite
0.37	GO:0044297	cell body
0.37	GO:0045177	apical part of cell
0.35	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

sp|P35001|NEUM_CHICK
Neuromodulin
Search

GAP43

0.92	Neuromodulin

0.78	GO:0040008	regulation of growth
0.56	GO:0016198	axon choice point recognition
0.56	GO:0051489	regulation of filopodium assembly
0.53	GO:0010001	glial cell differentiation
0.52	GO:0045165	cell fate commitment
0.41	GO:0042246	tissue regeneration
0.40	GO:0007339	binding of sperm to zona pellucida
0.39	GO:0031103	axon regeneration
0.35	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway

0.44	GO:0005516	calmodulin binding
0.39	GO:0035727	lysophosphatidic acid binding
0.38	GO:0001786	phosphatidylserine binding
0.37	GO:1901981	phosphatidylinositol phosphate binding

0.60	GO:0031527	filopodium membrane
0.55	GO:0014069	postsynaptic density
0.54	GO:0043005	neuron projection
0.44	GO:0030427	site of polarized growth
0.43	GO:0030054	cell junction
0.39	GO:0097060	synaptic membrane
0.39	GO:0005737	cytoplasm
0.35	GO:0043025	neuronal cell body
0.35	GO:0098793	presynapse

sp|P35062|H2A3_CHICK
Histone H2A-III
Search

0.48	GO:0006342	chromatin silencing
0.40	GO:0050830	defense response to Gram-positive bacterium
0.39	GO:0045087	innate immune response
0.38	GO:0051673	membrane disruption in other organism
0.37	GO:0006333	chromatin assembly or disassembly
0.37	GO:0034728	nucleosome organization
0.36	GO:0065004	protein-DNA complex assembly
0.36	GO:0006323	DNA packaging
0.35	GO:0006974	cellular response to DNA damage stimulus
0.35	GO:0032986	protein-DNA complex disassembly

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.43	GO:0031974	membrane-enclosed lumen
0.40	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle

sp|P35331|NRCAM_CHICK
Neuronal cell adhesion molecule
Search

NRCAM

0.87	Neuronal cell adhesion molecule

0.61	GO:0045162	clustering of voltage-gated sodium channels
0.55	GO:0001525	angiogenesis
0.54	GO:0098870	action potential propagation
0.53	GO:0034113	heterotypic cell-cell adhesion
0.53	GO:0031290	retinal ganglion cell axon guidance
0.52	GO:0019226	transmission of nerve impulse
0.50	GO:0010975	regulation of neuron projection development
0.49	GO:0007417	central nervous system development
0.44	GO:0008104	protein localization
0.39	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules

0.60	GO:0030506	ankyrin binding
0.55	GO:0086080	protein binding involved in heterotypic cell-cell adhesion
0.38	GO:0050839	cell adhesion molecule binding
0.37	GO:0001871	pattern binding
0.37	GO:0046982	protein heterodimerization activity
0.36	GO:0030246	carbohydrate binding

0.50	GO:0030424	axon
0.48	GO:0045202	synapse
0.41	GO:0005886	plasma membrane
0.37	GO:0005911	cell-cell junction
0.36	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0120038	plasma membrane bounded cell projection part
0.36	GO:0009986	cell surface
0.36	GO:0098552	side of membrane
0.35	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|P35431|CAV1_CHICK
Caveolin-1
Search

CAV1

0.82

Caveolin

0.85	GO:0070836	caveola assembly
0.64	GO:0031295	T cell costimulation
0.63	GO:0031623	receptor internalization
0.62	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.61	GO:1900085	negative regulation of peptidyl-tyrosine autophosphorylation
0.61	GO:1903609	negative regulation of inward rectifier potassium channel activity
0.60	GO:0033484	nitric oxide homeostasis
0.60	GO:0086098	angiotensin-activated signaling pathway involved in heart process
0.60	GO:0060355	positive regulation of cell adhesion molecule production
0.60	GO:0048550	negative regulation of pinocytosis

0.61	GO:0070320	inward rectifier potassium channel inhibitor activity
0.59	GO:0050998	nitric-oxide synthase binding
0.58	GO:0044325	ion channel binding
0.56	GO:0048365	Rac GTPase binding
0.56	GO:0051117	ATPase binding
0.56	GO:0032947	protein complex scaffold activity
0.55	GO:0016504	peptidase activator activity
0.53	GO:0030674	protein binding, bridging
0.53	GO:0019901	protein kinase binding
0.50	GO:0042802	identical protein binding

0.84	GO:0005901	caveola
0.74	GO:0000139	Golgi membrane
0.57	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex
0.57	GO:0002080	acrosomal membrane
0.56	GO:0005768	endosome
0.54	GO:0005925	focal adhesion
0.53	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005929	cilium
0.51	GO:0005938	cell cortex
0.47	GO:0005887	integral component of plasma membrane

sp|P35440|TSP2_CHICK
Thrombospondin-2
Search

THBS2

0.91	Thrombospondin-2

0.84	GO:0016525	negative regulation of angiogenesis
0.81	GO:0030198	extracellular matrix organization
0.72	GO:0007155	cell adhesion
0.43	GO:0006954	inflammatory response
0.40	GO:0002605	negative regulation of dendritic cell antigen processing and presentation
0.39	GO:0010754	negative regulation of cGMP-mediated signaling
0.39	GO:0010751	negative regulation of nitric oxide mediated signal transduction
0.39	GO:2001027	negative regulation of endothelial cell chemotaxis
0.39	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport
0.39	GO:0010757	negative regulation of plasminogen activation

0.83	GO:0008201	heparin binding
0.70	GO:0005509	calcium ion binding
0.44	GO:0050840	extracellular matrix binding
0.39	GO:0070052	collagen V binding
0.39	GO:0070051	fibrinogen binding
0.39	GO:0030169	low-density lipoprotein particle binding
0.39	GO:0001968	fibronectin binding
0.38	GO:0017134	fibroblast growth factor binding
0.38	GO:0001786	phosphatidylserine binding
0.38	GO:0005178	integrin binding

0.74	GO:0031012	extracellular matrix
0.55	GO:0031091	platelet alpha granule
0.49	GO:0005615	extracellular space
0.38	GO:0009897	external side of plasma membrane
0.35	GO:0016529	sarcoplasmic reticulum
0.35	GO:0043234	protein complex
0.31	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

sp|P35458|DCTN1_CHICK
Dynactin subunit 1
Search

DCTN1

0.91	Dynactin subunit 1

0.81	GO:0010970	transport along microtubule
0.54	GO:0090063	positive regulation of microtubule nucleation
0.53	GO:0051081	nuclear envelope disassembly
0.52	GO:0010457	centriole-centriole cohesion
0.52	GO:0032402	melanosome transport
0.51	GO:0000132	establishment of mitotic spindle orientation
0.51	GO:0034454	microtubule anchoring at centrosome
0.51	GO:0060236	regulation of mitotic spindle organization
0.50	GO:1905515	non-motile cilium assembly
0.49	GO:0042147	retrograde transport, endosome to Golgi

0.83	GO:0070840	dynein complex binding
0.48	GO:0019901	protein kinase binding
0.47	GO:0008017	microtubule binding
0.38	GO:0003774	motor activity
0.34	GO:0042802	identical protein binding

0.81	GO:0005869	dynactin complex
0.52	GO:0120103	centriolar subdistal appendage
0.52	GO:0035371	microtubule plus-end
0.50	GO:0099738	cell cortex region
0.50	GO:0005814	centriole
0.49	GO:0030904	retromer complex
0.49	GO:0005813	centrosome
0.49	GO:0000776	kinetochore
0.49	GO:0031252	cell leading edge
0.48	GO:0000922	spindle pole

sp|P35608|NF1_CHICK
Neurofibromin (Fragment)
Search

0.46	Neurofibromin (Fragment)

0.70	GO:0043087	regulation of GTPase activity
0.57	GO:0007165	signal transduction
0.53	GO:0043409	negative regulation of MAPK cascade
0.53	GO:0050890	cognition
0.53	GO:0045685	regulation of glial cell differentiation
0.52	GO:0061535	glutamate secretion, neurotransmission
0.52	GO:0061534	gamma-aminobutyric acid secretion, neurotransmission
0.51	GO:0001937	negative regulation of endothelial cell proliferation
0.51	GO:0021897	forebrain astrocyte development
0.51	GO:0043535	regulation of blood vessel endothelial cell migration

0.52	GO:0031210	phosphatidylcholine binding
0.52	GO:0008429	phosphatidylethanolamine binding
0.49	GO:0005096	GTPase activator activity
0.35	GO:0045545	syndecan binding
0.35	GO:0008017	microtubule binding

0.49	GO:0030425	dendrite
0.49	GO:0030424	axon
0.46	GO:0098793	presynapse
0.45	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane
0.37	GO:0005737	cytoplasm
0.37	GO:0005730	nucleolus
0.34	GO:0014069	postsynaptic density
0.33	GO:0043234	protein complex

sp|P35915|HMGCL_CHICK
Hydroxymethylglutaryl-CoA lyase, mitochondrial
Search

HMGCL

0.46	Hydroxymethylglutaryl-CoA lyase

0.65	GO:0046951	ketone body biosynthetic process
0.50	GO:0051262	protein tetramerization
0.48	GO:0007005	mitochondrion organization
0.43	GO:0006629	lipid metabolic process
0.37	GO:0070542	response to fatty acid
0.37	GO:0001889	liver development
0.37	GO:0007584	response to nutrient
0.36	GO:0042594	response to starvation
0.36	GO:0019318	hexose metabolic process
0.36	GO:0035383	thioester metabolic process

0.81	GO:0004419	hydroxymethylglutaryl-CoA lyase activity
0.48	GO:0042803	protein homodimerization activity
0.47	GO:0030145	manganese ion binding
0.47	GO:0005102	receptor binding
0.44	GO:0000287	magnesium ion binding
0.37	GO:0000062	fatty-acyl-CoA binding
0.36	GO:0003978	UDP-glucose 4-epimerase activity
0.36	GO:0004560	alpha-L-fucosidase activity
0.36	GO:0043177	organic acid binding

0.50	GO:0005777	peroxisome
0.43	GO:0044429	mitochondrial part
0.43	GO:0019866	organelle inner membrane
0.41	GO:0005829	cytosol
0.40	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005783	endoplasmic reticulum
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment
0.30	GO:0044425	membrane part

0.81	EC:4.1.3.4	GO:0004419
0.81	KEGG:R01360	GO:0004419

sp|P36195|TDT_CHICK
DNA nucleotidylexotransferase
Search

DNTT

0.97	DNA nucleotidylexotransferase

0.63	GO:0071897	DNA biosynthetic process
0.41	GO:0006304	DNA modification
0.38	GO:0033198	response to ATP
0.38	GO:0006281	DNA repair

0.81	GO:0003912	DNA nucleotidylexotransferase activity
0.66	GO:0003887	DNA-directed DNA polymerase activity
0.52	GO:0003677	DNA binding
0.51	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.58	GO:0005634	nucleus
0.48	GO:0005829	cytosol
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.36	GO:0005694	chromosome

0.81

EC:2.7.7.31

GO:0003912

sp|P36196|ACES_CHICK
Acetylcholinesterase
Search

0.46	Acetylcholinesterase

0.61	GO:0006581	acetylcholine catabolic process
0.56	GO:0002076	osteoblast development
0.56	GO:0045212	neurotransmitter receptor biosynthetic process
0.53	GO:0060041	retina development in camera-type eye
0.52	GO:0001919	regulation of receptor recycling
0.52	GO:0031623	receptor internalization
0.50	GO:0051262	protein tetramerization
0.48	GO:0007155	cell adhesion
0.47	GO:0007271	synaptic transmission, cholinergic
0.41	GO:0048593	camera-type eye morphogenesis

0.82	GO:0004104	cholinesterase activity
0.56	GO:0042166	acetylcholine binding
0.55	GO:0043236	laminin binding
0.53	GO:0005518	collagen binding
0.52	GO:0043621	protein self-association
0.50	GO:0042803	protein homodimerization activity
0.46	GO:0017171	serine hydrolase activity
0.38	GO:0001540	amyloid-beta binding
0.36	GO:0033265	choline binding
0.35	GO:0090729	toxin activity

0.56	GO:0045202	synapse
0.53	GO:0005605	basal lamina
0.51	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0005794	Golgi apparatus
0.48	GO:0009986	cell surface
0.47	GO:0005615	extracellular space
0.45	GO:0030054	cell junction
0.42	GO:0005886	plasma membrane
0.41	GO:0031225	anchored component of membrane
0.36	GO:0005635	nuclear envelope

0.82

EC:3.1.1.8

GO:0004104

sp|P36197|ZEB1_CHICK
Zinc finger E-box-binding homeobox 1
Search

ZEB1

0.97	Zinc finger E-box-binding homeobox 1

0.60	GO:0045602	negative regulation of endothelial cell differentiation
0.59	GO:0048752	semicircular canal morphogenesis
0.58	GO:0090103	cochlea morphogenesis
0.58	GO:0033081	regulation of T cell differentiation in thymus
0.58	GO:0051150	regulation of smooth muscle cell differentiation
0.57	GO:0048596	embryonic camera-type eye morphogenesis
0.57	GO:0010464	regulation of mesenchymal cell proliferation
0.56	GO:0071230	cellular response to amino acid stimulus
0.56	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
0.56	GO:0048704	embryonic skeletal system morphogenesis

0.58	GO:0070888	E-box binding
0.56	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.52	GO:0003682	chromatin binding
0.50	GO:0008134	transcription factor binding
0.41	GO:0046872	metal ion binding
0.35	GO:0003714	transcription corepressor activity
0.35	GO:0003713	transcription coactivator activity

0.59	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.49	GO:0005829	cytosol
0.48	GO:0043233	organelle lumen
0.44	GO:0044446	intracellular organelle part

sp|P36377|SPRC_CHICK
SPARC
Search

SPARC

0.95	Secreted protein acidic and rich in cysteine

0.61	GO:0007165	signal transduction
0.54	GO:0001937	negative regulation of endothelial cell proliferation
0.54	GO:0001501	skeletal system development
0.54	GO:0010595	positive regulation of endothelial cell migration
0.53	GO:0016525	negative regulation of angiogenesis
0.53	GO:0043473	pigmentation
0.51	GO:0048513	animal organ development
0.51	GO:0071363	cellular response to growth factor stimulus
0.47	GO:0022604	regulation of cell morphogenesis
0.44	GO:0060037	pharyngeal system development

0.84	GO:0050840	extracellular matrix binding
0.83	GO:0005518	collagen binding
0.70	GO:0005509	calcium ion binding

0.76	GO:0005578	proteinaceous extracellular matrix
0.73	GO:0005615	extracellular space
0.57	GO:0031092	platelet alpha granule membrane
0.53	GO:0016363	nuclear matrix
0.50	GO:0009986	cell surface
0.42	GO:0044420	extracellular matrix component
0.35	GO:0071682	endocytic vesicle lumen
0.35	GO:0031093	platelet alpha granule lumen
0.34	GO:0005739	mitochondrion
0.33	GO:0005886	plasma membrane

sp|P36381|CXA8_CHICK
Gap junction alpha-8 protein
Search

GJA8

0.64	Gap junction alpha-8 protein (Fragment)

0.60	GO:0007154	cell communication
0.53	GO:0002088	lens development in camera-type eye
0.48	GO:0007601	visual perception
0.40	GO:0055085	transmembrane transport
0.40	GO:0048050	post-embryonic eye morphogenesis
0.40	GO:0003161	cardiac conduction system development
0.39	GO:0055008	cardiac muscle tissue morphogenesis
0.39	GO:0008016	regulation of heart contraction
0.38	GO:0051260	protein homooligomerization
0.35	GO:0023052	signaling

0.55	GO:0005243	gap junction channel activity
0.34	GO:0005515	protein binding

0.84	GO:0005922	connexin complex
0.36	GO:0005887	integral component of plasma membrane

sp|P37042|GON1_CHICK
Progonadoliberin-1
Search

GNRH1

0.91	Chicken-I-type gonadotropin-releasing hormone

0.75	GO:0010469	regulation of receptor activity
0.70	GO:0007275	multicellular organism development
0.59	GO:2000354	regulation of ovarian follicle development
0.55	GO:0045471	response to ethanol
0.54	GO:0030336	negative regulation of cell migration
0.54	GO:0051961	negative regulation of nervous system development
0.54	GO:0010721	negative regulation of cell development
0.52	GO:0014070	response to organic cyclic compound
0.52	GO:0033993	response to lipid
0.51	GO:0009725	response to hormone

0.87	GO:0005183	gonadotropin hormone-releasing hormone activity
0.45	GO:0031530	gonadotropin-releasing hormone receptor binding

0.66	GO:0005576	extracellular region
0.46	GO:0043204	perikaryon
0.44	GO:0043005	neuron projection
0.39	GO:1990008	neurosecretory vesicle
0.38	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.36	GO:0098793	presynapse
0.36	GO:0005798	Golgi-associated vesicle
0.36	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

sp|P37067|OLF1_CHICK
Olfactory receptor-like protein COR1
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.54	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P37068|OLF2_CHICK
Olfactory receptor-like protein COR2
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.55	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P37069|OLF3_CHICK
Olfactory receptor-like protein COR3
Search

0.43	Olfactory receptor

0.74	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.69	GO:0007186	G-protein coupled receptor signaling pathway

0.74	GO:0004984	olfactory receptor activity
0.69	GO:0004930	G-protein coupled receptor activity
0.54	GO:0005549	odorant binding

0.54	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P37070|OLF4_CHICK
Olfactory receptor-like protein COR4
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.54	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P37071|OLF5_CHICK
Olfactory receptor-like protein COR5
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.70	GO:0004930	G-protein coupled receptor activity
0.55	GO:0005549	odorant binding

0.54	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P37072|OLF6_CHICK
Olfactory receptor-like protein COR6
Search

0.43	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.70	GO:0004930	G-protein coupled receptor activity
0.54	GO:0005549	odorant binding

0.54	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P37301|MYP0_CHICK
Myelin protein P0
Search

MPZ

0.97	Myelin protein zero

0.58	GO:0098743	cell aggregation
0.57	GO:0042552	myelination
0.54	GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules
0.45	GO:0023052	signaling
0.44	GO:0007154	cell communication
0.43	GO:0051716	cellular response to stimulus
0.41	GO:0065007	biological regulation
0.38	GO:0045217	cell-cell junction maintenance
0.36	GO:0060028	convergent extension involved in axis elongation

0.35	GO:0000062	fatty-acyl-CoA binding
0.34	GO:0005515	protein binding
0.33	GO:0005198	structural molecule activity

0.77	GO:0043209	myelin sheath
0.67	GO:0005887	integral component of plasma membrane
0.38	GO:0016323	basolateral plasma membrane
0.38	GO:0005791	rough endoplasmic reticulum
0.38	GO:0005764	lysosome

sp|P37383|RAD51_CHICK
DNA repair protein RAD51 homolog 1
Search

RAD51

0.74	DNA repair protein RAD51 homolog A

0.85	GO:1990426	mitotic recombination-dependent replication fork processing
0.75	GO:0000724	double-strand break repair via homologous recombination
0.55	GO:0090735	DNA repair complex assembly
0.55	GO:0072757	cellular response to camptothecin
0.54	GO:0051106	positive regulation of DNA ligation
0.53	GO:0072711	cellular response to hydroxyurea
0.53	GO:0010212	response to ionizing radiation
0.53	GO:0006312	mitotic recombination
0.52	GO:0010569	regulation of double-strand break repair via homologous recombination
0.52	GO:0070192	chromosome organization involved in meiotic cell cycle

0.73	GO:0000150	recombinase activity
0.72	GO:0003697	single-stranded DNA binding
0.71	GO:0003690	double-stranded DNA binding
0.69	GO:0008094	DNA-dependent ATPase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0070182	DNA polymerase binding
0.50	GO:0008022	protein C-terminus binding

0.60	GO:0005634	nucleus
0.50	GO:0035861	site of double-strand break
0.50	GO:0000793	condensed chromosome
0.49	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0000781	chromosome, telomeric region
0.47	GO:0031974	membrane-enclosed lumen
0.46	GO:0000785	chromatin
0.45	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.41	GO:0043234	protein complex

sp|P38024|PUR6_CHICK
Multifunctional protein ADE2
Search

PAICS

0.70	Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase

0.71	GO:0006189	'de novo' IMP biosynthetic process
0.40	GO:0043473	pigmentation
0.40	GO:0060041	retina development in camera-type eye
0.39	GO:0043009	chordate embryonic development
0.34	GO:0000082	G1/S transition of mitotic cell cycle
0.34	GO:0009113	purine nucleobase biosynthetic process

0.79	GO:0004639	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
0.48	GO:0045296	cadherin binding
0.45	GO:0042802	identical protein binding
0.39	GO:0004638	phosphoribosylaminoimidazole carboxylase activity
0.35	GO:0032555	purine ribonucleotide binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0008144	drug binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.37	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.79	EC:6.3.2.6	GO:0004639
0.79	KEGG:R04591	GO:0004639

sp|P38529|HSF1_CHICK
Heat shock factor protein 1
Search

HSF1

0.71	Heat shock transcription factor

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1900365	positive regulation of mRNA polyadenylation
0.55	GO:0072738	cellular response to diamide
0.54	GO:0043497	regulation of protein heterodimerization activity
0.54	GO:1903936	cellular response to sodium arsenite
0.54	GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining
0.54	GO:0070207	protein homotrimerization
0.53	GO:0071280	cellular response to copper ion
0.53	GO:0071480	cellular response to gamma radiation

0.64	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.55	GO:0061770	translation elongation factor binding
0.53	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding
0.53	GO:1990841	promoter-specific chromatin binding
0.52	GO:0043621	protein self-association
0.52	GO:0051879	Hsp90 protein binding
0.51	GO:0031490	chromatin DNA binding
0.48	GO:0019901	protein kinase binding
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding

0.60	GO:0005634	nucleus
0.53	GO:0097431	mitotic spindle pole
0.50	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0035770	ribonucleoprotein granule
0.49	GO:0000776	kinetochore
0.49	GO:0005813	centrosome
0.45	GO:0070013	intracellular organelle lumen
0.45	GO:0005829	cytosol
0.40	GO:0000791	euchromatin
0.40	GO:0000792	heterochromatin

sp|P38530|HSF2_CHICK
Heat shock factor protein 2
Search

HSF2

0.97	LOW QUALITY PROTEIN: heat shock factor protein 2

0.68	GO:0006357	regulation of transcription by RNA polymerase II
0.53	GO:0006366	transcription by RNA polymerase II
0.52	GO:0045893	positive regulation of transcription, DNA-templated
0.51	GO:0007283	spermatogenesis
0.41	GO:0070207	protein homotrimerization
0.40	GO:1903935	response to sodium arsenite
0.39	GO:0031397	negative regulation of protein ubiquitination
0.38	GO:0050821	protein stabilization
0.38	GO:0010243	response to organonitrogen compound
0.37	GO:0014070	response to organic cyclic compound

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.50	GO:0042803	protein homodimerization activity
0.38	GO:0001047	core promoter binding
0.35	GO:0003713	transcription coactivator activity

0.61	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm
0.36	GO:0005694	chromosome

sp|P38531|HSF3_CHICK
Heat shock factor protein 3
Search

HSF2

0.89	Heat shock transcription factor 3

0.64	GO:0006357	regulation of transcription by RNA polymerase II
0.57	GO:0034605	cellular response to heat
0.45	GO:0010628	positive regulation of gene expression
0.45	GO:0006366	transcription by RNA polymerase II
0.44	GO:0007283	spermatogenesis
0.44	GO:1903508	positive regulation of nucleic acid-templated transcription
0.44	GO:0002088	lens development in camera-type eye
0.39	GO:0070207	protein homotrimerization
0.39	GO:0031620	regulation of fever generation
0.38	GO:1902808	positive regulation of cell cycle G1/S phase transition

0.63	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.50	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003690	double-stranded DNA binding
0.45	GO:0042803	protein homodimerization activity
0.37	GO:0001047	core promoter binding
0.35	GO:0032183	SUMO binding
0.34	GO:0033613	activating transcription factor binding
0.34	GO:0003713	transcription coactivator activity

0.60	GO:0005634	nucleus
0.43	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm
0.35	GO:0005694	chromosome
0.30	GO:0031224	intrinsic component of membrane

sp|P39022|RAD52_CHICK
DNA repair protein RAD52 homolog
Search

RAD52

0.95	DNA repair protein RAD52 homolog

0.85	GO:0045002	double-strand break repair via single-strand annealing
0.85	GO:0000730	DNA recombinase assembly
0.56	GO:2000819	regulation of nucleotide-excision repair
0.55	GO:0000729	DNA double-strand break processing
0.51	GO:0051260	protein homooligomerization
0.49	GO:0034599	cellular response to oxidative stress
0.34	GO:0007015	actin filament organization

0.49	GO:0042802	identical protein binding
0.49	GO:0003697	single-stranded DNA binding
0.35	GO:0003785	actin monomer binding
0.33	GO:0005509	calcium ion binding

0.60	GO:0005634	nucleus
0.48	GO:0032993	protein-DNA complex
0.43	GO:0043234	protein complex
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part

sp|P39963|CCNB3_CHICK
G2/mitotic-specific cyclin-B3
Search

CCNB3

0.77

Cyclin B

0.82	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.81	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
0.35	GO:0051301	cell division
0.35	GO:0007049	cell cycle
0.33	GO:0006397	mRNA processing

0.78

GO:0019901

protein kinase binding

0.59	GO:0005634	nucleus
0.32	GO:0043234	protein complex
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P40220|RABP1_CHICK
Cellular retinoic acid-binding protein 1
Search

CRABP1

0.93	Cellular retinoic acid binding protein I

0.84	GO:0042573	retinoic acid metabolic process
0.83	GO:0042363	fat-soluble vitamin catabolic process
0.83	GO:0016103	diterpenoid catabolic process
0.67	GO:0072329	monocarboxylic acid catabolic process
0.58	GO:0048385	regulation of retinoic acid receptor signaling pathway
0.50	GO:0048672	positive regulation of collateral sprouting
0.49	GO:0035115	embryonic forelimb morphogenesis
0.34	GO:0016102	diterpenoid biosynthetic process
0.34	GO:0051260	protein homooligomerization
0.34	GO:0008544	epidermis development

0.86	GO:0001972	retinoic acid binding
0.46	GO:0019841	retinol binding
0.45	GO:0016918	retinal binding
0.36	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding
0.33	GO:0005198	structural molecule activity

0.49	GO:0005737	cytoplasm
0.45	GO:0005634	nucleus
0.42	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part
0.37	GO:0070852	cell body fiber
0.36	GO:0030424	axon
0.35	GO:0012505	endomembrane system
0.35	GO:0070062	extracellular exosome
0.35	GO:0045111	intermediate filament cytoskeleton
0.34	GO:0099512	supramolecular fiber

sp|P40618|HMGB3_CHICK
High mobility group protein B3
Search

HMGB3

0.96	High mobility group box 3

0.56	GO:0032392	DNA geometric change
0.51	GO:0045578	negative regulation of B cell differentiation
0.49	GO:0045638	negative regulation of myeloid cell differentiation
0.38	GO:0045087	innate immune response
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.34	GO:0006310	DNA recombination
0.33	GO:0007275	multicellular organism development

0.67	GO:0000400	four-way junction DNA binding
0.67	GO:0008301	DNA binding, bending
0.40	GO:0003723	RNA binding
0.35	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.36	GO:0005694	chromosome
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P40665|CH01_CHICK
SRY-related protein CH1 (Fragment)
Search

SOX1

0.97	SRY-box containing transcription factor 1a (Fragment)

0.58	GO:0048731	system development
0.51	GO:1903506	regulation of nucleic acid-templated transcription
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.50	GO:0010468	regulation of gene expression
0.45	GO:0048518	positive regulation of biological process
0.44	GO:0006366	transcription by RNA polymerase II
0.44	GO:0060573	cell fate specification involved in pattern specification
0.43	GO:1990830	cellular response to leukemia inhibitory factor
0.42	GO:0009953	dorsal/ventral pattern formation
0.41	GO:0060322	head development

0.55	GO:0003677	DNA binding
0.46	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.44	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.35	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

0.36

GO:0032440

sp|P40666|CH02_CHICK
SRY-related protein CH2 (Fragment)
Search

0.87	SRY-box containing protein 2 (Fragment)

0.54	GO:2001141	regulation of RNA biosynthetic process
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.49	GO:0007399	nervous system development
0.49	GO:0009649	entrainment of circadian clock
0.47	GO:0030154	cell differentiation
0.46	GO:0051960	regulation of nervous system development
0.46	GO:0060284	regulation of cell development
0.46	GO:0030334	regulation of cell migration
0.46	GO:0007601	visual perception

0.55	GO:0003677	DNA binding
0.46	GO:0003682	chromatin binding
0.45	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.45	GO:0046982	protein heterodimerization activity
0.41	GO:0035198	miRNA binding
0.40	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding

0.61	GO:0005634	nucleus
0.45	GO:0005667	transcription factor complex
0.41	GO:0044446	intracellular organelle part
0.37	GO:0005829	cytosol
0.37	GO:0070013	intracellular organelle lumen
0.30	GO:0016020	membrane

0.34

GO:0032440

sp|P40667|CH03_CHICK
SRY-related protein CH3 (Fragment)
Search

SOX3

0.91	SRY-box containing transcription factor 3 (Fragment)

0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.46	GO:0007530	sex determination
0.43	GO:0043049	otic placode formation
0.42	GO:0007417	central nervous system development
0.42	GO:0007422	peripheral nervous system development
0.41	GO:0048699	generation of neurons
0.40	GO:0044093	positive regulation of molecular function
0.39	GO:0048518	positive regulation of biological process

0.55	GO:0003677	DNA binding
0.38	GO:0140110	transcription regulator activity
0.37	GO:0008013	beta-catenin binding
0.36	GO:0001067	regulatory region nucleic acid binding

0.61	GO:0005634	nucleus
0.41	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part
0.34	GO:0005667	transcription factor complex
0.33	GO:0005737	cytoplasm

sp|P40668|CH04_CHICK
SRY-related protein CH4 (Fragment)
Search

0.90	SRY-box containing protein 2 (Fragment)

0.53	GO:2001141	regulation of RNA biosynthetic process
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.51	GO:0007399	nervous system development
0.50	GO:0009649	entrainment of circadian clock
0.48	GO:0030154	cell differentiation
0.47	GO:0051960	regulation of nervous system development
0.47	GO:0060284	regulation of cell development
0.47	GO:0030334	regulation of cell migration
0.47	GO:0007601	visual perception

0.55	GO:0003677	DNA binding
0.47	GO:0003682	chromatin binding
0.46	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.45	GO:0046982	protein heterodimerization activity
0.41	GO:0035198	miRNA binding
0.40	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding

0.61	GO:0005634	nucleus
0.46	GO:0005667	transcription factor complex
0.41	GO:0044446	intracellular organelle part
0.38	GO:0005829	cytosol
0.37	GO:0070013	intracellular organelle lumen
0.30	GO:0016020	membrane

0.34

GO:0032440

sp|P40669|CH07_CHICK
SRY-related protein CH7 (Fragment)
Search

0.90	SRY-box containing protein 2 (Fragment)

0.53	GO:2001141	regulation of RNA biosynthetic process
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.51	GO:0007399	nervous system development
0.49	GO:0009649	entrainment of circadian clock
0.47	GO:0030154	cell differentiation
0.46	GO:0051960	regulation of nervous system development
0.46	GO:0060284	regulation of cell development
0.46	GO:0030334	regulation of cell migration
0.46	GO:0007601	visual perception

0.55	GO:0003677	DNA binding
0.46	GO:0003682	chromatin binding
0.45	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.44	GO:0046982	protein heterodimerization activity
0.41	GO:0035198	miRNA binding
0.40	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding

0.61	GO:0005634	nucleus
0.45	GO:0005667	transcription factor complex
0.40	GO:0044446	intracellular organelle part
0.37	GO:0005829	cytosol
0.37	GO:0070013	intracellular organelle lumen
0.30	GO:0016020	membrane

0.34

GO:0032440

sp|P40670|CH31_CHICK
SRY-related protein CH31 (Fragment)
Search

0.92	SRY-box containing protein 2 (Fragment)

0.53	GO:2001141	regulation of RNA biosynthetic process
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.50	GO:0007399	nervous system development
0.49	GO:0009649	entrainment of circadian clock
0.48	GO:0030154	cell differentiation
0.47	GO:0051960	regulation of nervous system development
0.46	GO:0060284	regulation of cell development
0.46	GO:0030334	regulation of cell migration
0.46	GO:0007601	visual perception

0.55	GO:0003677	DNA binding
0.46	GO:0003682	chromatin binding
0.45	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.45	GO:0046982	protein heterodimerization activity
0.41	GO:0035198	miRNA binding
0.40	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding

0.61	GO:0005634	nucleus
0.45	GO:0005667	transcription factor complex
0.41	GO:0044446	intracellular organelle part
0.37	GO:0005829	cytosol
0.37	GO:0070013	intracellular organelle lumen
0.30	GO:0016020	membrane

0.34

GO:0032440

sp|P40671|CH32_CHICK
SRY-related protein CH32 (Fragment)
Search

0.97	SRY-box containing transcription factor 14a (Fragment)

0.53	GO:2001141	regulation of RNA biosynthetic process
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.50	GO:0009649	entrainment of circadian clock
0.50	GO:2001222	regulation of neuron migration
0.47	GO:0007601	visual perception
0.43	GO:0021854	hypothalamus development
0.37	GO:0051253	negative regulation of RNA metabolic process
0.37	GO:0010558	negative regulation of macromolecule biosynthetic process
0.37	GO:0031327	negative regulation of cellular biosynthetic process

0.55	GO:0003677	DNA binding
0.46	GO:0003682	chromatin binding
0.45	GO:0046982	protein heterodimerization activity
0.45	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.45	GO:0005667	transcription factor complex
0.39	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.34

GO:0032440

sp|P41125|RL13_CHICK
60S ribosomal protein L13
Search

RPL13

0.68	Ribosomal protein L13

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.41	GO:0051726	regulation of cell cycle
0.35	GO:0097421	liver regeneration
0.34	GO:0006508	proteolysis
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.63	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.36	GO:0004222	metalloendopeptidase activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0005515	protein binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.47	GO:0005829	cytosol
0.45	GO:0005730	nucleolus
0.44	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.36

GO:0004222

sp|P41239|CSK_CHICK
Tyrosine-protein kinase CSK
Search

CSK

0.59	Tyrosine-protein kinase

0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.57	GO:0042997	negative regulation of Golgi to plasma membrane protein transport
0.51	GO:0042127	regulation of cell proliferation
0.48	GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway
0.46	GO:0034332	adherens junction organization
0.46	GO:0060027	convergent extension involved in gastrulation
0.45	GO:0046777	protein autophosphorylation
0.44	GO:0001817	regulation of cytokine production
0.44	GO:0007417	central nervous system development
0.44	GO:0045087	innate immune response

0.79	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.55	GO:0034236	protein kinase A catalytic subunit binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0042802	identical protein binding
0.42	GO:0005102	receptor binding
0.35	GO:0070064	proline-rich region binding
0.35	GO:0019903	protein phosphatase binding
0.35	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

0.49	GO:0005911	cell-cell junction
0.44	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.35	GO:0098857	membrane microdomain
0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:2.7.10.2

GO:0004715

sp|P41263|RET4_CHICK
Retinol-binding protein 4
Search

RBP4

0.97	Plasma retinol binding protein 4

0.86	GO:0034633	retinol transport
0.56	GO:0032526	response to retinoic acid
0.55	GO:0030277	maintenance of gastrointestinal epithelium
0.54	GO:0042572	retinol metabolic process
0.54	GO:0032024	positive regulation of insulin secretion
0.52	GO:0042593	glucose homeostasis
0.51	GO:0001654	eye development
0.48	GO:0019319	hexose biosynthetic process
0.48	GO:0006006	glucose metabolic process
0.41	GO:0001889	liver development

0.86	GO:0034632	retinol transmembrane transporter activity
0.83	GO:0005501	retinoid binding
0.55	GO:0043178	alcohol binding
0.46	GO:0019842	vitamin binding
0.36	GO:0046982	protein heterodimerization activity
0.34	GO:0019904	protein domain specific binding
0.34	GO:0005102	receptor binding

0.50	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:0060418	yolk plasma
0.35	GO:0030136	clathrin-coated vesicle
0.34	GO:0043234	protein complex
0.34	GO:0033165	interphotoreceptor matrix
0.33	GO:0005829	cytosol

sp|P41366|VMO1_CHICK
Vitelline membrane outer layer protein 1
Search

VMO1

0.93	Vitelline membrane outer layer protein 1

0.66	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part
0.30	GO:0005623	cell

sp|P41534|PACA_CHICK
Glucagon family neuropeptides
Search

ADCYAP1

0.93	Pituitary adenylate cyclase-activating polypeptide

0.75	GO:0010469	regulation of receptor activity
0.58	GO:0007218	neuropeptide signaling pathway
0.57	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production
0.55	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.54	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.54	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.53	GO:0007399	nervous system development
0.52	GO:0045860	positive regulation of protein kinase activity
0.51	GO:0120036	plasma membrane bounded cell projection organization
0.51	GO:0043547	positive regulation of GTPase activity

0.79	GO:0005179	hormone activity
0.57	GO:0051428	peptide hormone receptor binding
0.42	GO:0005057	signal transducer activity, downstream of receptor
0.41	GO:0031858	pituitary adenylate cyclase-activating polypeptide receptor binding

0.66	GO:0005576	extracellular region
0.40	GO:0043005	neuron projection
0.38	GO:0043204	perikaryon
0.38	GO:0098793	presynapse
0.37	GO:0120038	plasma membrane bounded cell projection part
0.37	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

sp|P42165|IFNA1_CHICK
Interferon type A1/A2
Search

0.86	Interferon type B

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.57	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.57	GO:0002323	natural killer cell activation involved in immune response
0.56	GO:0042100	B cell proliferation
0.56	GO:0002286	T cell activation involved in immune response
0.55	GO:0043330	response to exogenous dsRNA
0.55	GO:0030183	B cell differentiation
0.54	GO:0002250	adaptive immune response
0.53	GO:0006959	humoral immune response

0.81	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.50	GO:0032403	protein complex binding

0.73

GO:0005615

extracellular space

sp|P42292|CD166_CHICK
CD166 antigen
Search

ALCAM

0.97	Activated leukocyte cell adhesion molecule

0.58	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.55	GO:0007411	axon guidance
0.43	GO:1902284	neuron projection extension involved in neuron projection guidance
0.43	GO:0048675	axon extension
0.42	GO:0002250	adaptive immune response
0.41	GO:0060385	axonogenesis involved in innervation
0.40	GO:0021885	forebrain cell migration
0.36	GO:0098743	cell aggregation
0.35	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.33	GO:0007165	signal transduction

0.52	GO:0042802	identical protein binding
0.34	GO:0005102	receptor binding

0.59	GO:0042101	T cell receptor complex
0.58	GO:0001772	immunological synapse
0.55	GO:0030424	axon
0.53	GO:0036477	somatodendritic compartment
0.53	GO:0009897	external side of plasma membrane
0.52	GO:0044297	cell body
0.48	GO:0031226	intrinsic component of plasma membrane
0.40	GO:0120038	plasma membrane bounded cell projection part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome

sp|P42324|HPCL1_CHICK
Hippocalcin-like protein 1
Search

HPCAL1

0.85	Hippocalcin-like protein 1

0.70	GO:0005509	calcium ion binding
0.36	GO:0005515	protein binding

0.38	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|P42558|RAN_CHICK
GTP-binding nuclear protein Ran
Search

RAN

0.69	GTP-binding nuclear protein Ran

0.72	GO:0006913	nucleocytoplasmic transport
0.65	GO:0015031	protein transport
0.53	GO:0051030	snRNA transport
0.52	GO:0006404	RNA import into nucleus
0.51	GO:0034504	protein localization to nucleus
0.50	GO:0033750	ribosome localization
0.49	GO:0071166	ribonucleoprotein complex localization
0.49	GO:0051169	nuclear transport
0.48	GO:0051656	establishment of organelle localization
0.48	GO:0000070	mitotic sister chromatid segregation

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.46	GO:0019003	GDP binding
0.46	GO:0070883	pre-miRNA binding
0.45	GO:0045296	cadherin binding
0.43	GO:0000287	magnesium ion binding
0.43	GO:0046982	protein heterodimerization activity
0.38	GO:0061676	importin-alpha family protein binding
0.38	GO:0045505	dynein intermediate chain binding
0.36	GO:0019904	protein domain specific binding

0.61	GO:0005634	nucleus
0.48	GO:0042565	RNA nuclear export complex
0.45	GO:0030496	midbody
0.45	GO:0055037	recycling endosome
0.45	GO:0005814	centriole
0.42	GO:0000785	chromatin
0.42	GO:0031967	organelle envelope
0.41	GO:0042470	melanosome
0.41	GO:0070013	intracellular organelle lumen
0.38	GO:0002177	manchette

sp|P42683|LCK_CHICK
Proto-oncogene tyrosine-protein kinase LCK
Search

LCK

0.60	Proto-oncogene tyrosine-protein kinase LCK

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.74	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.73	GO:0006882	cellular zinc ion homeostasis
0.73	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.71	GO:0030217	T cell differentiation
0.66	GO:0050870	positive regulation of T cell activation
0.64	GO:0050853	B cell receptor signaling pathway
0.62	GO:0006470	protein dephosphorylation
0.61	GO:0046777	protein autophosphorylation
0.61	GO:0042493	response to drug

0.77	GO:0004713	protein tyrosine kinase activity
0.75	GO:0042169	SH2 domain binding
0.69	GO:0042610	CD8 receptor binding
0.67	GO:0042608	T cell receptor binding
0.66	GO:0004722	protein serine/threonine phosphatase activity
0.64	GO:0043548	phosphatidylinositol 3-kinase binding
0.63	GO:0001784	phosphotyrosine residue binding
0.63	GO:0051117	ATPase binding
0.62	GO:0019903	protein phosphatase binding
0.61	GO:0008022	protein C-terminus binding

0.74	GO:0000242	pericentriolar material
0.69	GO:0098857	membrane microdomain
0.64	GO:0001772	immunological synapse
0.60	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.50	GO:0070062	extracellular exosome
0.48	GO:0005911	cell-cell junction
0.45	GO:0005829	cytosol
0.44	GO:0030139	endocytic vesicle

0.77	EC:2.7.10	GO:0004713
0.47	KEGG:R04545	GO:0046934

sp|P43031|INHA_CHICK
Inhibin alpha chain
Search

INHA

0.94	Inhibin alpha chain

0.76	GO:0010469	regulation of receptor activity
0.60	GO:0042541	hemoglobin biosynthetic process
0.52	GO:0042127	regulation of cell proliferation
0.50	GO:0051726	regulation of cell cycle
0.49	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.49	GO:0060395	SMAD protein signal transduction
0.48	GO:0030509	BMP signaling pathway
0.46	GO:0043408	regulation of MAPK cascade
0.45	GO:0048468	cell development
0.45	GO:0042981	regulation of apoptotic process

0.78	GO:0008083	growth factor activity
0.71	GO:0005179	hormone activity
0.49	GO:0005160	transforming growth factor beta receptor binding
0.47	GO:0005125	cytokine activity
0.38	GO:0034711	inhibin binding
0.36	GO:0046982	protein heterodimerization activity
0.32	GO:0008234	cysteine-type peptidase activity

0.66	GO:0005576	extracellular region
0.59	GO:0034673	inhibin-betaglycan-ActRII complex
0.38	GO:0001917	photoreceptor inner segment
0.37	GO:0001750	photoreceptor outer segment
0.37	GO:0043025	neuronal cell body
0.33	GO:0005737	cytoplasm

0.32

GO:0008234

sp|P43233|CATB_CHICK
Cathepsin B
Search

CTSB

0.82	Cathepsin B

0.68	GO:0050790	regulation of catalytic activity
0.61	GO:0006508	proteolysis
0.55	GO:0097067	cellular response to thyroid hormone stimulus
0.55	GO:0030574	collagen catabolic process
0.52	GO:0060429	epithelium development
0.51	GO:0046697	decidualization
0.49	GO:0044257	cellular protein catabolic process
0.48	GO:0030154	cell differentiation
0.45	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.45	GO:0044409	entry into host

0.74	GO:0004197	cysteine-type endopeptidase activity
0.54	GO:0043394	proteoglycan binding
0.52	GO:0005518	collagen binding
0.35	GO:0030984	kininogen binding
0.34	GO:0043621	protein self-association
0.34	GO:0042277	peptide binding
0.33	GO:0004252	serine-type endopeptidase activity

0.53	GO:0005764	lysosome
0.51	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005615	extracellular space
0.48	GO:0005730	nucleolus
0.42	GO:0005739	mitochondrion
0.41	GO:0042470	melanosome
0.36	GO:1903561	extracellular vesicle
0.35	GO:0031904	endosome lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0005775	vacuolar lumen

0.74

GO:0004197

sp|P43305|PRVU_CHICK
Parvalbumin, thymic CPV3
Search

0.89	Novel protein containing two EF hand domains

0.37	GO:1905591	regulation of optical nerve axon regeneration
0.37	GO:1902336	positive regulation of retinal ganglion cell axon guidance
0.36	GO:0048687	positive regulation of sprouting of injured axon
0.36	GO:0048690	regulation of axon extension involved in regeneration
0.36	GO:0070207	protein homotrimerization
0.36	GO:0045773	positive regulation of axon extension
0.36	GO:0051289	protein homotetramerization
0.35	GO:0051480	regulation of cytosolic calcium ion concentration
0.35	GO:0009611	response to wounding
0.33	GO:0010941	regulation of cell death

0.70	GO:0005509	calcium ion binding
0.35	GO:0042803	protein homodimerization activity
0.35	GO:0046982	protein heterodimerization activity

0.43	GO:0030424	axon
0.40	GO:0043679	axon terminus
0.39	GO:0030425	dendrite
0.36	GO:0016528	sarcoplasm
0.35	GO:0005615	extracellular space
0.34	GO:0099512	supramolecular fiber
0.34	GO:0031982	vesicle
0.33	GO:0005634	nucleus
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|P43347|TCTP_CHICK
Translationally-controlled tumor protein homolog
Search

TPT1

0.73	Translationally-controlled tumor

0.71	GO:2000384	negative regulation of ectoderm development
0.64	GO:0019827	stem cell population maintenance
0.57	GO:0030154	cell differentiation
0.46	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.41	GO:0007283	spermatogenesis
0.41	GO:0009615	response to virus
0.38	GO:1903575	cornified envelope assembly
0.38	GO:0006874	cellular calcium ion homeostasis
0.38	GO:0008283	cell proliferation
0.38	GO:0006816	calcium ion transport

0.59	GO:0008017	microtubule binding
0.57	GO:0005509	calcium ion binding
0.57	GO:0008134	transcription factor binding
0.38	GO:0003723	RNA binding
0.37	GO:0051082	unfolded protein binding
0.35	GO:0008270	zinc ion binding

0.61	GO:0005615	extracellular space
0.58	GO:0005829	cytosol
0.56	GO:0045298	tubulin complex
0.55	GO:0005654	nucleoplasm
0.54	GO:0005771	multivesicular body
0.43	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

sp|P43449|CCNA2_CHICK
Cyclin-A2
Search

0.62

Cyclin A

0.55	GO:0000086	G2/M transition of mitotic cell cycle
0.54	GO:0044843	cell cycle G1/S phase transition
0.54	GO:0016572	histone phosphorylation
0.53	GO:0007265	Ras protein signal transduction
0.49	GO:0045893	positive regulation of transcription, DNA-templated
0.49	GO:0051726	regulation of cell cycle
0.43	GO:0007423	sensory organ development
0.41	GO:0071373	cellular response to luteinizing hormone stimulus
0.40	GO:0071314	cellular response to cocaine
0.40	GO:1990314	cellular response to insulin-like growth factor stimulus

0.54	GO:0097472	cyclin-dependent protein kinase activity
0.51	GO:0019901	protein kinase binding
0.50	GO:0019904	protein domain specific binding
0.35	GO:0001103	RNA polymerase II repressing transcription factor binding

0.61	GO:0005634	nucleus
0.58	GO:0097124	cyclin A2-CDK2 complex
0.47	GO:0031974	membrane-enclosed lumen
0.47	GO:0005829	cytosol
0.42	GO:0044446	intracellular organelle part
0.39	GO:0097123	cyclin A1-CDK2 complex
0.37	GO:0015630	microtubule cytoskeleton
0.34	GO:0001750	photoreceptor outer segment
0.34	GO:0034464	BBSome
0.34	GO:0097014	ciliary plasm

sp|P43679|ACHB3_CHICK
Neuronal acetylcholine receptor subunit beta-3
Search

CHRNB3

0.93	Neuronal acetylcholine receptor subunit beta-3

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.45	GO:0035094	response to nicotine
0.45	GO:0007271	synaptic transmission, cholinergic
0.45	GO:0007274	neuromuscular synaptic transmission
0.39	GO:0051291	protein heterooligomerization
0.38	GO:0006812	cation transport

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.46	GO:0042166	acetylcholine binding

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.45	GO:0005892	acetylcholine-gated channel complex
0.38	GO:0043005	neuron projection

sp|P43691|GATA4_CHICK
Transcription factor GATA-4 (Fragment)
Search

GATA4

0.96	GATA binding protein 4

0.73	GO:0060575	intestinal epithelial cell differentiation
0.72	GO:0045893	positive regulation of transcription, DNA-templated
0.72	GO:0003290	atrial septum secundum morphogenesis
0.67	GO:0003197	endocardial cushion development
0.65	GO:0008584	male gonad development
0.65	GO:0006357	regulation of transcription by RNA polymerase II
0.59	GO:0003260	cardioblast migration
0.58	GO:0003318	cell migration to the midline involved in heart development
0.58	GO:0060029	convergent extension involved in organogenesis
0.57	GO:0048797	swim bladder formation

0.69	GO:0070410	co-SMAD binding
0.65	GO:0044212	transcription regulatory region DNA binding
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.62	GO:0003713	transcription coactivator activity
0.61	GO:0003700	DNA binding transcription factor activity
0.61	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.61	GO:0008134	transcription factor binding
0.50	GO:0003690	double-stranded DNA binding
0.49	GO:0003682	chromatin binding

0.62	GO:0005667	transcription factor complex
0.61	GO:0016604	nuclear body

sp|P43692|GATA5_CHICK
Transcription factor GATA-5
Search

GATA5

0.93	GATA binding protein 5

0.73	GO:0045893	positive regulation of transcription, DNA-templated
0.71	GO:0035295	tube development
0.70	GO:0055123	digestive system development
0.69	GO:0060429	epithelium development
0.67	GO:0030154	cell differentiation
0.66	GO:0006357	regulation of transcription by RNA polymerase II
0.63	GO:0003260	cardioblast migration
0.62	GO:0003318	cell migration to the midline involved in heart development
0.62	GO:0071773	cellular response to BMP stimulus
0.59	GO:0001889	liver development

0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0044212	transcription regulatory region DNA binding
0.63	GO:0008270	zinc ion binding
0.62	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.57	GO:0003690	double-stranded DNA binding
0.52	GO:0008134	transcription factor binding
0.50	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.50	GO:0070410	co-SMAD binding
0.49	GO:0003682	chromatin binding
0.46	GO:0003713	transcription coactivator activity

0.61	GO:0005634	nucleus
0.53	GO:0005667	transcription factor complex
0.42	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part

sp|P43693|GATA6_CHICK
Transcription factor GATA-6
Search

GATA6

0.90	Transcription factor GATA-6

0.69	GO:0045893	positive regulation of transcription, DNA-templated
0.62	GO:0048645	animal organ formation
0.61	GO:0001889	liver development
0.60	GO:0003007	heart morphogenesis
0.59	GO:0035295	tube development
0.59	GO:0055123	digestive system development
0.58	GO:0060429	epithelium development
0.58	GO:0003318	cell migration to the midline involved in heart development
0.57	GO:0030154	cell differentiation
0.56	GO:0048738	cardiac muscle tissue development

0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0001085	RNA polymerase II transcription factor binding
0.53	GO:0044212	transcription regulatory region DNA binding
0.51	GO:0003682	chromatin binding
0.50	GO:0003690	double-stranded DNA binding
0.49	GO:0070491	repressing transcription factor binding
0.47	GO:0019901	protein kinase binding
0.35	GO:0070410	co-SMAD binding

0.58	GO:0005634	nucleus
0.50	GO:0005667	transcription factor complex
0.43	GO:0012505	endomembrane system
0.41	GO:0031967	organelle envelope
0.41	GO:0031090	organelle membrane
0.33	GO:0070013	intracellular organelle lumen

sp|P46156|GLL1_CHICK
Gallinacin-1
Search

0.62	Beta-defensin 1 antimicrobial peptide

0.72	GO:0006952	defense response
0.57	GO:0009617	response to bacterium
0.54	GO:0009620	response to fungus
0.52	GO:0031640	killing of cells of other organism

0.66	GO:0005576	extracellular region
0.51	GO:0030141	secretory granule

sp|P46157|GLL1A_CHICK
Gallinacin-1 alpha
Search

0.63	Beta-defensin 1 antimicrobial peptide

0.72	GO:0006952	defense response
0.55	GO:0009617	response to bacterium
0.52	GO:0009620	response to fungus
0.51	GO:0031640	killing of cells of other organism

0.66	GO:0005576	extracellular region
0.50	GO:0030141	secretory granule

sp|P46158|GLL2_CHICK
Gallinacin-2
Search

0.73	Beta-defensin

0.72	GO:0006952	defense response
0.41	GO:0009617	response to bacterium

0.66	GO:0005576	extracellular region
0.37	GO:0030141	secretory granule

sp|P46692|HMD1_CHICK
Homeobox protein CHOX-CAD
Search

CDX1

0.94	Homeobox protein CHOX-CAD

0.65	GO:0007275	multicellular organism development
0.62	GO:0014807	regulation of somitogenesis
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.53	GO:0009653	anatomical structure morphogenesis
0.51	GO:0048522	positive regulation of cellular process
0.50	GO:0010557	positive regulation of macromolecule biosynthetic process
0.50	GO:0006366	transcription by RNA polymerase II
0.49	GO:0051173	positive regulation of nitrogen compound metabolic process

0.62	GO:0043565	sequence-specific DNA binding
0.58	GO:0035326	enhancer binding
0.56	GO:0001012	RNA polymerase II regulatory region DNA binding
0.55	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.53	GO:0003690	double-stranded DNA binding
0.45	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.45	GO:0003714	transcription corepressor activity
0.33	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.45	GO:0017053	transcriptional repressor complex
0.43	GO:0000793	condensed chromosome
0.41	GO:0043233	organelle lumen
0.39	GO:0043234	protein complex
0.38	GO:0044446	intracellular organelle part

sp|P46896|GTR1_CHICK
Solute carrier family 2, facilitated glucose transporter member 1
Search

SLC2A1

0.91	Solute carrier family 2, facilitated glucose transporter member 1

0.72	GO:1904659	glucose transmembrane transport
0.53	GO:0070837	dehydroascorbic acid transport
0.52	GO:0071548	response to dexamethasone
0.52	GO:0032868	response to insulin
0.50	GO:0042149	cellular response to glucose starvation
0.47	GO:0006461	protein complex assembly
0.42	GO:0002040	sprouting angiogenesis
0.39	GO:1904016	response to Thyroglobulin triiodothyronine
0.39	GO:0046323	glucose import
0.39	GO:0061300	cerebellum vasculature development

0.72	GO:0005355	glucose transmembrane transporter activity
0.53	GO:0043621	protein self-association
0.53	GO:0033300	dehydroascorbic acid transmembrane transporter activity
0.47	GO:0042802	identical protein binding
0.37	GO:0042910	xenobiotic transmembrane transporter activity
0.37	GO:0019900	kinase binding

0.52	GO:0001939	female pronucleus
0.51	GO:0030864	cortical actin cytoskeleton
0.51	GO:0030496	midbody
0.49	GO:0016323	basolateral plasma membrane
0.49	GO:0016324	apical plasma membrane
0.48	GO:0045121	membrane raft
0.46	GO:0031982	vesicle
0.46	GO:0005887	integral component of plasma membrane
0.44	GO:0005829	cytosol
0.38	GO:0014704	intercalated disc

sp|P46936|YAP1_CHICK
Transcriptional coactivator YAP1
Search

YAP1

0.68	Transcriptional coactivator YAP1

0.70	GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation
0.70	GO:0060449	bud elongation involved in lung branching
0.69	GO:1902459	positive regulation of stem cell population maintenance
0.68	GO:0046620	regulation of organ growth
0.68	GO:0048368	lateral mesoderm development
0.68	GO:0060487	lung epithelial cell differentiation
0.68	GO:0048339	paraxial mesoderm development
0.68	GO:2000737	negative regulation of stem cell differentiation
0.67	GO:0010837	regulation of keratinocyte proliferation
0.67	GO:0030857	negative regulation of epithelial cell differentiation

0.68	GO:0044212	transcription regulatory region DNA binding
0.68	GO:0070064	proline-rich region binding
0.64	GO:0008022	protein C-terminus binding
0.61	GO:0003713	transcription coactivator activity
0.61	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.60	GO:0003682	chromatin binding
0.59	GO:1990837	sequence-specific double-stranded DNA binding
0.45	GO:0033613	activating transcription factor binding
0.44	GO:0003714	transcription corepressor activity
0.42	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.59	GO:0005667	transcription factor complex
0.55	GO:0005829	cytosol
0.43	GO:0000785	chromatin
0.38	GO:0070013	intracellular organelle lumen
0.30	GO:0016020	membrane

sp|P47191|SYT1_CHICK
Synaptotagmin-1
Search

SYT1

0.88	Synaptotagmin Ia

0.82	GO:0099643	signal release from synapse
0.82	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.75	GO:0006836	neurotransmitter transport
0.72	GO:0001505	regulation of neurotransmitter levels
0.68	GO:0051649	establishment of localization in cell
0.62	GO:1903861	positive regulation of dendrite extension
0.59	GO:0017158	regulation of calcium ion-dependent exocytosis
0.56	GO:0017156	calcium ion regulated exocytosis
0.56	GO:0097479	synaptic vesicle localization
0.56	GO:0014059	regulation of dopamine secretion

0.81	GO:0005544	calcium-dependent phospholipid binding
0.57	GO:0050750	low-density lipoprotein particle receptor binding
0.56	GO:0019905	syntaxin binding
0.55	GO:0048306	calcium-dependent protein binding
0.50	GO:0005509	calcium ion binding
0.48	GO:0030276	clathrin binding
0.47	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.40	GO:0001786	phosphatidylserine binding
0.40	GO:0005516	calmodulin binding
0.39	GO:0008022	protein C-terminus binding

0.81	GO:0008021	synaptic vesicle
0.59	GO:0099501	exocytic vesicle membrane
0.57	GO:0031045	dense core granule
0.55	GO:0042734	presynaptic membrane
0.52	GO:0030424	axon
0.48	GO:0005794	Golgi apparatus
0.48	GO:0005829	cytosol
0.45	GO:0042584	chromaffin granule membrane
0.41	GO:0030054	cell junction
0.40	GO:0060076	excitatory synapse

sp|P47236|PAX1_CHICK
Paired box protein Pax-1 (Fragment)
Search

PAX9

0.78	Paired box 1

0.70	GO:0007275	multicellular organism development
0.60	GO:0009653	anatomical structure morphogenesis
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0036037	CD8-positive, alpha-beta T cell activation
0.50	GO:0035710	CD4-positive, alpha-beta T cell activation
0.50	GO:0009888	tissue development
0.48	GO:1902680	positive regulation of RNA biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.50	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0005249	voltage-gated potassium channel activity
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex
0.33	GO:0005887	integral component of plasma membrane

sp|P47237|PAX6_CHICK
Paired box protein Pax-6 (Fragment)
Search

PAX6

0.77	Paired box protein Pax-6

0.67	GO:0007275	multicellular organism development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0006351	transcription, DNA-templated
0.54	GO:0009786	regulation of asymmetric cell division
0.54	GO:0048505	regulation of timing of cell differentiation
0.53	GO:0002068	glandular epithelial cell development
0.53	GO:2000178	negative regulation of neural precursor cell proliferation
0.53	GO:0035883	enteroendocrine cell differentiation

0.65	GO:0043565	sequence-specific DNA binding
0.54	GO:0070410	co-SMAD binding
0.54	GO:0071837	HMG box domain binding
0.53	GO:0070412	R-SMAD binding
0.53	GO:0035035	histone acetyltransferase binding
0.51	GO:0001047	core promoter binding
0.51	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.51	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.49	GO:0019901	protein kinase binding

0.61	GO:0005634	nucleus
0.47	GO:0000785	chromatin
0.46	GO:0005829	cytosol
0.46	GO:0070013	intracellular organelle lumen
0.34	GO:0005667	transcription factor complex

0.36

KEGG:R03876

GO:0004842

sp|P47807|MYO1A_CHICK
Unconventional myosin-Ia
Search

MYO1A

0.84	LOW QUALITY PROTEIN: unconventional myosin-Ia

0.74	GO:0007018	microtubule-based movement
0.52	GO:0030033	microvillus assembly
0.49	GO:0007605	sensory perception of sound
0.49	GO:0051648	vesicle localization
0.44	GO:0006892	post-Golgi vesicle-mediated transport
0.44	GO:0030029	actin filament-based process
0.43	GO:0097435	supramolecular fiber organization
0.42	GO:0007010	cytoskeleton organization
0.38	GO:0007217	tachykinin receptor signaling pathway
0.36	GO:0045056	transcytosis

0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.73	GO:0003779	actin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0032403	protein complex binding
0.48	GO:0000146	microfilament motor activity
0.44	GO:0045296	cadherin binding
0.42	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding

0.77	GO:0016459	myosin complex
0.55	GO:0005884	actin filament
0.53	GO:0005903	brush border
0.53	GO:0098858	actin-based cell projection
0.52	GO:0016328	lateral plasma membrane
0.51	GO:0009925	basal plasma membrane
0.50	GO:0045177	apical part of cell
0.50	GO:0044853	plasma membrane raft
0.49	GO:0030864	cortical actin cytoskeleton
0.46	GO:0032588	trans-Golgi network membrane

sp|P47826|RLA0_CHICK
60S acidic ribosomal protein P0
Search

RPLP0

0.67	60S acidic ribosomal protein P0

0.66	GO:0042254	ribosome biogenesis
0.47	GO:0071353	cellular response to interleukin-4
0.36	GO:1904401	cellular response to Thyroid stimulating hormone
0.35	GO:0035722	interleukin-12-mediated signaling pathway
0.35	GO:0010269	response to selenium ion
0.35	GO:1904628	cellular response to phorbol 13-acetate 12-myristate
0.35	GO:0007595	lactation
0.35	GO:0071320	cellular response to cAMP
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.43	GO:0003735	structural constituent of ribosome
0.34	GO:0042277	peptide binding
0.34	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.49	GO:0036464	cytoplasmic ribonucleoprotein granule
0.46	GO:0044445	cytosolic part
0.46	GO:0005783	endoplasmic reticulum
0.45	GO:0030425	dendrite
0.42	GO:0005634	nucleus
0.41	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P47832|RL26_CHICK
60S ribosomal protein L26 (Fragment)
Search

RPL26

0.81	Ribosomal protein L26, pseudogene 2

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.55	GO:1902167	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.54	GO:1904803	regulation of translation involved in cellular response to UV
0.54	GO:1902164	positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.54	GO:0010467	gene expression
0.53	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
0.53	GO:0009059	macromolecule biosynthetic process
0.52	GO:0042273	ribosomal large subunit biogenesis
0.52	GO:0071480	cellular response to gamma radiation

0.64	GO:0003735	structural constituent of ribosome
0.49	GO:0048027	mRNA 5'-UTR binding
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding

0.71	GO:0015934	large ribosomal subunit
0.52	GO:0022626	cytosolic ribosome
0.46	GO:0005730	nucleolus
0.45	GO:0005654	nucleoplasm
0.37	GO:0070062	extracellular exosome
0.34	GO:0043195	terminal bouton
0.30	GO:0031224	intrinsic component of membrane

sp|P47836|RS4_CHICK
40S ribosomal protein S4
Search

RPS4X

0.67	Ribosomal protein S4, X-linked X isoform variant (Fragment)

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.48	GO:0008284	positive regulation of cell proliferation
0.48	GO:0045727	positive regulation of translation
0.46	GO:0007275	multicellular organism development
0.38	GO:0060322	head development
0.37	GO:0045471	response to ethanol
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

0.63	GO:0003735	structural constituent of ribosome
0.62	GO:0019843	rRNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.50	GO:0005844	polysome
0.49	GO:0044445	cytosolic part
0.48	GO:0036464	cytoplasmic ribonucleoprotein granule
0.42	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0031012	extracellular matrix
0.33	GO:0043233	organelle lumen
0.33	GO:0005634	nucleus

sp|P47838|RS6_CHICK
40S ribosomal protein S6
Search

RPS6

0.63	Ribosomal protein S6 (Fragment)

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.52	GO:0002309	T cell proliferation involved in immune response
0.52	GO:0022605	oogenesis stage
0.52	GO:0006924	activation-induced cell death of T cells
0.50	GO:0042274	ribosomal small subunit biogenesis
0.50	GO:0048821	erythrocyte development
0.49	GO:0033077	T cell differentiation in thymus

0.63	GO:0003735	structural constituent of ribosome
0.46	GO:0019901	protein kinase binding
0.34	GO:0003729	mRNA binding

0.61	GO:0005840	ribosome
0.50	GO:0030425	dendrite
0.49	GO:0044445	cytosolic part
0.48	GO:0005844	polysome
0.47	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0044297	cell body
0.47	GO:0036464	cytoplasmic ribonucleoprotein granule
0.45	GO:0005730	nucleolus
0.44	GO:0005783	endoplasmic reticulum
0.33	GO:0005654	nucleoplasm

sp|P47990|XDH_CHICK
Xanthine dehydrogenase/oxidase
Search

XDH

0.53	XDH xanthine dehydrogenase

0.61	GO:0009115	xanthine catabolic process
0.59	GO:2001213	negative regulation of vasculogenesis
0.59	GO:0022900	electron transport chain
0.57	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway
0.57	GO:0045602	negative regulation of endothelial cell differentiation
0.56	GO:1900745	positive regulation of p38MAPK cascade
0.55	GO:0001937	negative regulation of endothelial cell proliferation
0.55	GO:0051898	negative regulation of protein kinase B signaling
0.54	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.54	GO:2000379	positive regulation of reactive oxygen species metabolic process

0.81	GO:0016727	oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor
0.80	GO:0004854	xanthine dehydrogenase activity
0.74	GO:0043546	molybdopterin cofactor binding
0.69	GO:0051537	2 iron, 2 sulfur cluster binding
0.66	GO:0050660	flavin adenine dinucleotide binding
0.65	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.62	GO:0005506	iron ion binding
0.60	GO:0009055	electron transfer activity
0.50	GO:0030151	molybdenum ion binding
0.50	GO:0042803	protein homodimerization activity

0.53	GO:0016529	sarcoplasmic reticulum
0.43	GO:0005829	cytosol
0.40	GO:0005615	extracellular space
0.40	GO:0005777	peroxisome
0.36	GO:0002197	xanthine dehydrogenase complex
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:1.17.3

GO:0016727

sp|P48143|VIP_CHICK
VIP peptides
Search

VIP

0.97	Vasoactive intestinal polypeptide

0.82	GO:0070459	prolactin secretion
0.78	GO:0048255	mRNA stabilization
0.76	GO:0010469	regulation of receptor activity
0.59	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.57	GO:0019933	cAMP-mediated signaling
0.52	GO:0045732	positive regulation of protein catabolic process
0.50	GO:0032880	regulation of protein localization
0.45	GO:0030819	positive regulation of cAMP biosynthetic process
0.43	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.41	GO:0048242	epinephrine secretion

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.38	GO:0005622	intracellular
0.38	GO:0097458	neuron part
0.37	GO:0120025	plasma membrane bounded cell projection
0.37	GO:0044297	cell body
0.30	GO:0016020	membrane

sp|P48306|NDUB4_CHICK
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4
Search

NDUFB4

0.74	NADH:ubiquinone oxidoreductase subunit B4

0.77	GO:0032981	mitochondrial respiratory chain complex I assembly
0.65	GO:0006979	response to oxidative stress
0.53	GO:0055114	oxidation-reduction process

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.74	GO:0005747	mitochondrial respiratory chain complex I
0.72	GO:0031965	nuclear membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|P48430|SOX2_CHICK
Transcription factor SOX-2
Search

SOX2

0.96	Sex determining region Y-box 2

0.59	GO:0021536	diencephalon development
0.58	GO:0035270	endocrine system development
0.58	GO:0048839	inner ear development
0.57	GO:0001714	endodermal cell fate specification
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0048732	gland development
0.56	GO:0010468	regulation of gene expression
0.56	GO:0001654	eye development
0.55	GO:0009611	response to wounding

0.56	GO:0035198	miRNA binding
0.55	GO:0003677	DNA binding
0.51	GO:0001067	regulatory region nucleic acid binding
0.47	GO:0003700	DNA binding transcription factor activity
0.44	GO:0003682	chromatin binding
0.36	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.47	GO:0005829	cytosol
0.47	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.38	GO:0005667	transcription factor complex

sp|P48433|SOX3_CHICK
Transcription factor SOX-3
Search

SOX3

0.91	SRY-box containing transcription factor 3

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0032502	developmental process
0.45	GO:0032501	multicellular organismal process
0.43	GO:0022414	reproductive process
0.43	GO:0048518	positive regulation of biological process
0.42	GO:0044093	positive regulation of molecular function
0.39	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.39	GO:0009611	response to wounding

0.54	GO:0003677	DNA binding
0.41	GO:0140110	transcription regulator activity
0.39	GO:0001067	regulatory region nucleic acid binding
0.39	GO:0035198	miRNA binding
0.38	GO:0008013	beta-catenin binding
0.35	GO:0003682	chromatin binding
0.33	GO:0032440	2-alkenal reductase [NAD(P)] activity

0.61	GO:0005634	nucleus
0.43	GO:0070013	intracellular organelle lumen
0.39	GO:0044446	intracellular organelle part
0.36	GO:0005829	cytosol

0.33

GO:0032440

sp|P48434|SOX9_CHICK
Transcription factor SOX-9
Search

SOX9

0.94	SRY sex determining region Y-box 9

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.59	GO:0030916	otic vesicle formation
0.58	GO:0060767	epithelial cell proliferation involved in prostate gland development
0.57	GO:2000741	positive regulation of mesenchymal stem cell differentiation
0.57	GO:0060784	regulation of cell proliferation involved in tissue homeostasis
0.57	GO:0060516	primary prostatic bud elongation
0.57	GO:2000020	positive regulation of male gonad development
0.57	GO:0072289	metanephric nephron tubule formation
0.57	GO:0019100	male germ-line sex determination
0.57	GO:0060221	retinal rod cell differentiation

0.73	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.55	GO:0003677	DNA binding
0.53	GO:0034236	protein kinase A catalytic subunit binding
0.52	GO:0097157	pre-mRNA intronic binding
0.52	GO:0003682	chromatin binding
0.50	GO:0001067	regulatory region nucleic acid binding
0.50	GO:0008013	beta-catenin binding
0.46	GO:0046982	protein heterodimerization activity
0.44	GO:0004672	protein kinase activity
0.38	GO:0043425	bHLH transcription factor binding

0.61	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.45	GO:0070013	intracellular organelle lumen
0.41	GO:0044446	intracellular organelle part
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P48435|SOX11_CHICK
Transcription factor SOX-11
Search

0.94	Transcription factor SOX-4

0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0060253	negative regulation of glial cell proliferation
0.55	GO:0061386	closure of optic fissure
0.55	GO:0010468	regulation of gene expression
0.54	GO:2000648	positive regulation of stem cell proliferation
0.53	GO:0045669	positive regulation of osteoblast differentiation
0.53	GO:0050672	negative regulation of lymphocyte proliferation
0.53	GO:2001109	regulation of lens epithelial cell proliferation
0.53	GO:0072395	signal transduction involved in cell cycle checkpoint

0.60	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.50	GO:0001105	RNA polymerase II transcription coactivator activity
0.49	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0008135	translation factor activity, RNA binding
0.36	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm

sp|P48440|OST48_CHICK
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Search

DDOST

0.78	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

0.85	GO:0018279	protein N-linked glycosylation via asparagine
0.52	GO:0042110	T cell activation
0.50	GO:0034097	response to cytokine
0.38	GO:0006334	nucleosome assembly
0.37	GO:0007018	microtubule-based movement
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0070828	heterochromatin organization
0.32	GO:0006355	regulation of transcription, DNA-templated

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.37	GO:0003777	microtubule motor activity
0.37	GO:0008017	microtubule binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0003677	DNA binding
0.34	GO:0003682	chromatin binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.42	GO:0043234	protein complex
0.41	GO:1990234	transferase complex
0.37	GO:0000786	nucleosome
0.35	GO:0035577	azurophil granule membrane
0.35	GO:0005634	nucleus
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.65

EC:2.4

GO:0016757

sp|P48463|PP2AA_CHICK
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
Search

PPP2CA

0.47	Serine/threonine-protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.52	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.51	GO:0008637	apoptotic mitochondrial changes
0.50	GO:0007498	mesoderm development
0.50	GO:0042542	response to hydrogen peroxide
0.49	GO:0034976	response to endoplasmic reticulum stress
0.48	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.48	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.47	GO:0046677	response to antibiotic
0.42	GO:1904528	positive regulation of microtubule binding

0.72	GO:0004721	phosphoprotein phosphatase activity
0.52	GO:0050811	GABA receptor binding
0.51	GO:0008022	protein C-terminus binding
0.48	GO:0046982	protein heterodimerization activity
0.37	GO:0046872	metal ion binding
0.36	GO:0004362	glutathione-disulfide reductase activity
0.35	GO:1990405	protein antigen binding
0.35	GO:0031698	beta-2 adrenergic receptor binding
0.35	GO:0048156	tau protein binding
0.35	GO:0043422	protein kinase B binding

0.57	GO:0000159	protein phosphatase type 2A complex
0.50	GO:0000775	chromosome, centromeric region
0.45	GO:0005829	cytosol
0.43	GO:0000922	spindle pole
0.40	GO:0005886	plasma membrane
0.39	GO:0005634	nucleus
0.38	GO:0070062	extracellular exosome
0.35	GO:0043195	terminal bouton
0.34	GO:0014069	postsynaptic density
0.33	GO:0005739	mitochondrion

0.72

EC:3.1.3.16

GO:0004721

sp|P48800|FGF2_CHICK
Fibroblast growth factor 2
Search

FGF2

0.61	Fibroblast growth factor

0.84	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.63	GO:0001525	angiogenesis
0.61	GO:0051781	positive regulation of cell division
0.58	GO:0045766	positive regulation of angiogenesis
0.57	GO:0030154	cell differentiation
0.57	GO:0001759	organ induction
0.57	GO:0010595	positive regulation of endothelial cell migration
0.55	GO:0042127	regulation of cell proliferation
0.55	GO:0035295	tube development

0.85	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.61	GO:0008201	heparin binding
0.50	GO:0044548	S100 protein binding
0.49	GO:0005178	integrin binding
0.39	GO:0090722	receptor-receptor interaction
0.38	GO:0042056	chemoattractant activity
0.38	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.37	GO:0005125	cytokine activity
0.37	GO:0030544	Hsp70 protein binding

0.66	GO:0005576	extracellular region
0.54	GO:0005938	cell cortex
0.50	GO:0005829	cytosol
0.48	GO:0005634	nucleus
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0044446	intracellular organelle part

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|P48801|FGF3_CHICK
Fibroblast growth factor 3
Search

FGF3

0.62	Fibroblast growth factor

0.83	GO:0008543	fibroblast growth factor receptor signaling pathway
0.75	GO:0010469	regulation of receptor activity
0.56	GO:0055026	negative regulation of cardiac muscle tissue development
0.52	GO:0008284	positive regulation of cell proliferation
0.50	GO:0030916	otic vesicle formation
0.49	GO:0048920	posterior lateral line neuromast primordium migration
0.49	GO:0021572	rhombomere 6 development
0.49	GO:0021985	neurohypophysis development
0.49	GO:0060118	vestibular receptor cell development
0.49	GO:0021703	locus ceruleus development

0.84	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0042056	chemoattractant activity
0.35	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.35	GO:0008201	heparin binding
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0004713	protein tyrosine kinase activity

0.66	GO:0005576	extracellular region
0.37	GO:0005794	Golgi apparatus
0.36	GO:0009986	cell surface
0.35	GO:0005634	nucleus
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0005886	plasma membrane
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|P48804|FGF4_CHICK
Fibroblast growth factor 4
Search

FGF4

0.62	Fibroblast growth factor

0.81	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.55	GO:0001502	cartilage condensation
0.55	GO:0060591	chondroblast differentiation
0.54	GO:2000544	regulation of endothelial cell chemotaxis to fibroblast growth factor
0.53	GO:0010463	mesenchymal cell proliferation
0.52	GO:0060363	cranial suture morphogenesis
0.52	GO:0008284	positive regulation of cell proliferation
0.52	GO:0060561	apoptotic process involved in morphogenesis
0.51	GO:0035116	embryonic hindlimb morphogenesis

0.83	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.35	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.34	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.34	GO:0008201	heparin binding
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0004713	protein tyrosine kinase activity

0.65	GO:0005576	extracellular region
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

sp|P48984|TEAD4_CHICK
Transcriptional enhancer factor TEF-3
Search

TEAD4

0.91	Transcriptional enhancer factor TEF-3

0.80	GO:0035329	hippo signaling
0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.54	GO:0006351	transcription, DNA-templated
0.51	GO:0051254	positive regulation of RNA metabolic process
0.51	GO:0010557	positive regulation of macromolecule biosynthetic process
0.51	GO:0031328	positive regulation of cellular biosynthetic process
0.46	GO:0048568	embryonic organ development
0.38	GO:1902459	positive regulation of stem cell population maintenance

0.59	GO:0003700	DNA binding transcription factor activity
0.51	GO:0003677	DNA binding
0.47	GO:0001085	RNA polymerase II transcription factor binding
0.44	GO:0001067	regulatory region nucleic acid binding
0.37	GO:0001223	transcription coactivator binding
0.37	GO:0001134	transcription factor activity, transcription factor recruiting
0.36	GO:0046982	protein heterodimerization activity

0.53	GO:0005634	nucleus
0.44	GO:0005667	transcription factor complex
0.44	GO:0043233	organelle lumen
0.40	GO:0044446	intracellular organelle part
0.34	GO:0032993	protein-DNA complex
0.32	GO:0005737	cytoplasm

sp|P49024|PAXI_CHICK
Paxillin
Search

PXN

0.77	Myocardial ischemic preconditioning associated protein 7

0.82	GO:0007160	cell-matrix adhesion
0.49	GO:0060396	growth hormone receptor signaling pathway
0.49	GO:0051496	positive regulation of stress fiber assembly
0.49	GO:0043542	endothelial cell migration
0.48	GO:0007179	transforming growth factor beta receptor signaling pathway
0.45	GO:0034614	cellular response to reactive oxygen species
0.43	GO:0035994	response to muscle stretch
0.40	GO:0061055	myotome development
0.37	GO:0010951	negative regulation of endopeptidase activity
0.34	GO:0042254	ribosome biogenesis

0.61	GO:0017166	vinculin binding
0.53	GO:0046872	metal ion binding
0.50	GO:0038191	neuropilin binding
0.48	GO:0008013	beta-catenin binding
0.38	GO:0004867	serine-type endopeptidase inhibitor activity

0.69	GO:0005856	cytoskeleton
0.56	GO:0005925	focal adhesion
0.47	GO:0030027	lamellipodium
0.45	GO:0005886	plasma membrane
0.44	GO:0044446	intracellular organelle part
0.43	GO:0005829	cytosol

sp|P49140|SKI_CHICK
Ski oncogene
Search

SKI

0.68	Nuclear oncoprotein skia

0.59	GO:0010626	negative regulation of Schwann cell proliferation
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0030514	negative regulation of BMP signaling pathway
0.57	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.57	GO:0032926	negative regulation of activin receptor signaling pathway
0.56	GO:0045668	negative regulation of osteoblast differentiation
0.56	GO:0070207	protein homotrimerization
0.55	GO:0043388	positive regulation of DNA binding
0.55	GO:0060395	SMAD protein signal transduction
0.54	GO:0014902	myotube differentiation

0.77	GO:0046332	SMAD binding
0.59	GO:0070491	repressing transcription factor binding
0.54	GO:0019904	protein domain specific binding
0.53	GO:0003714	transcription corepressor activity
0.52	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0019901	protein kinase binding
0.48	GO:0042803	protein homodimerization activity
0.45	GO:0008270	zinc ion binding
0.44	GO:0043565	sequence-specific DNA binding
0.40	GO:0046811	histone deacetylase inhibitor activity

0.54	GO:0016605	PML body
0.51	GO:0005813	centrosome
0.49	GO:0005667	transcription factor complex
0.38	GO:0017053	transcriptional repressor complex
0.33	GO:0005737	cytoplasm

sp|P49147|PA24A_CHICK
Cytosolic phospholipase A2
Search

PLA2G4A

0.66	Cytosolic phospholipase A2

0.80	GO:0009395	phospholipid catabolic process
0.57	GO:0071236	cellular response to antibiotic
0.55	GO:0046456	icosanoid biosynthetic process
0.53	GO:0050482	arachidonic acid secretion
0.51	GO:0042127	regulation of cell proliferation
0.43	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.37	GO:0019369	arachidonic acid metabolic process
0.36	GO:0022602	ovulation cycle process
0.36	GO:0008585	female gonad development
0.36	GO:0036150	phosphatidylserine acyl-chain remodeling

0.82	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.82	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.79	GO:0004623	phospholipase A2 activity
0.56	GO:0005544	calcium-dependent phospholipid binding
0.53	GO:0046872	metal ion binding
0.44	GO:0004622	lysophospholipase activity
0.35	GO:0035035	histone acetyltransferase binding
0.35	GO:0008970	phosphatidylcholine 1-acylhydrolase activity

0.55	GO:0005811	lipid droplet
0.49	GO:0005829	cytosol
0.48	GO:0005794	Golgi apparatus
0.48	GO:0005783	endoplasmic reticulum
0.41	GO:0031410	cytoplasmic vesicle
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane

0.79

EC:3.1.1.4

GO:0004623

sp|P49152|CRBA4_CHICK
Beta-crystallin A4
Search

CRYBA4

0.96	Beta crystallin A4 chain

0.55	GO:0007601	visual perception
0.50	GO:0043010	camera-type eye development
0.35	GO:2000210	positive regulation of anoikis
0.35	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling
0.34	GO:0051898	negative regulation of protein kinase B signaling
0.34	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.34	GO:0032007	negative regulation of TOR signaling
0.34	GO:0043043	peptide biosynthetic process
0.34	GO:0001818	negative regulation of cytokine production
0.34	GO:0044267	cellular protein metabolic process

0.72	GO:0005212	structural constituent of eye lens
0.35	GO:0003735	structural constituent of ribosome
0.34	GO:0005515	protein binding

0.35	GO:0015935	small ribosomal subunit
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P49285|MTR1A_CHICK
Melatonin receptor type 1A
Search

MTNR1A

0.97	Melatonin receptor

0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.54	GO:0030828	positive regulation of cGMP biosynthetic process
0.45	GO:0007623	circadian rhythm
0.38	GO:0045820	negative regulation of glycolytic process
0.38	GO:0046325	negative regulation of glucose import
0.35	GO:0007617	mating behavior

0.85	GO:0008502	melatonin receptor activity
0.53	GO:0042562	hormone binding
0.37	GO:0097159	organic cyclic compound binding
0.36	GO:0033218	amide binding
0.34	GO:0008144	drug binding
0.33	GO:0005515	protein binding
0.32	GO:1901363	heterocyclic compound binding

0.50	GO:0043235	receptor complex
0.45	GO:0005887	integral component of plasma membrane

sp|P49288|MTR1C_CHICK
Melatonin receptor type 1C
Search

0.92	Melatonin receptor subtype one c

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.45	GO:0030828	positive regulation of cGMP biosynthetic process
0.40	GO:0007623	circadian rhythm
0.39	GO:0045820	negative regulation of glycolytic process
0.38	GO:0046325	negative regulation of glucose import
0.35	GO:0007617	mating behavior

0.85	GO:0008502	melatonin receptor activity
0.45	GO:0042562	hormone binding
0.36	GO:0033218	amide binding
0.34	GO:0097159	organic cyclic compound binding
0.34	GO:0008144	drug binding
0.33	GO:0005515	protein binding
0.32	GO:1901363	heterocyclic compound binding

0.43	GO:0043235	receptor complex
0.40	GO:0005887	integral component of plasma membrane

sp|P49337|WNT4_CHICK
Protein Wnt-4
Search

sp|P49339|WNT11_CHICK
Protein Wnt-11
Search

sp|P49416|SDC4_CHICK
Syndecan-4
Search

SDC4

0.80

Syndecan

0.60	GO:0042060	wound healing
0.60	GO:0002009	morphogenesis of an epithelium
0.59	GO:0008285	negative regulation of cell proliferation
0.57	GO:1903553	positive regulation of extracellular exosome assembly
0.56	GO:1903543	positive regulation of exosomal secretion
0.56	GO:1902725	negative regulation of satellite cell differentiation
0.56	GO:1902766	skeletal muscle satellite cell migration
0.56	GO:0010762	regulation of fibroblast migration
0.55	GO:0014842	regulation of skeletal muscle satellite cell proliferation
0.55	GO:0060122	inner ear receptor cell stereocilium organization

0.58	GO:0070053	thrombospondin receptor activity
0.52	GO:0042802	identical protein binding
0.42	GO:0030165	PDZ domain binding
0.41	GO:0005080	protein kinase C binding
0.38	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.38	GO:0001968	fibronectin binding
0.38	GO:0043395	heparan sulfate proteoglycan binding
0.35	GO:0046983	protein dimerization activity

0.51	GO:0009986	cell surface
0.40	GO:0044421	extracellular region part
0.40	GO:0005925	focal adhesion
0.38	GO:0043034	costamere
0.37	GO:0098857	membrane microdomain
0.37	GO:0005796	Golgi lumen
0.35	GO:0043202	lysosomal lumen
0.35	GO:0005886	plasma membrane
0.34	GO:0031982	vesicle
0.33	GO:0005788	endoplasmic reticulum lumen

sp|P49578|ACM3_CHICK
Muscarinic acetylcholine receptor M3
Search

CHRM3

0.81	Muscarinic acetylcholine receptor

0.85	GO:0046541	saliva secretion
0.84	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.83	GO:0045987	positive regulation of smooth muscle contraction
0.50	GO:0003056	regulation of vascular smooth muscle contraction
0.49	GO:0007271	synaptic transmission, cholinergic
0.49	GO:0006939	smooth muscle contraction
0.48	GO:0001696	gastric acid secretion
0.48	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.48	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.43	GO:0015872	dopamine transport

0.85	GO:0016907	G-protein coupled acetylcholine receptor activity
0.44	GO:0042166	acetylcholine binding
0.35	GO:0004435	phosphatidylinositol phospholipase C activity
0.35	GO:0005515	protein binding
0.33	GO:0098772	molecular function regulator

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.66	GO:0005887	integral component of plasma membrane
0.42	GO:0016323	basolateral plasma membrane
0.40	GO:0043679	axon terminus
0.40	GO:0032279	asymmetric synapse
0.39	GO:0030425	dendrite

0.35	EC:3.1.4.11	GO:0004435
0.35	KEGG:R03435	GO:0004435

sp|P49581|ACHA6_CHICK
Neuronal acetylcholine receptor subunit alpha-6
Search

CHRNA6

0.86	Cholinergic receptor nicotinic alpha 6 subunit

0.78	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.57	GO:0035094	response to nicotine
0.57	GO:0007274	neuromuscular synaptic transmission
0.53	GO:0007271	synaptic transmission, cholinergic
0.47	GO:0014059	regulation of dopamine secretion
0.46	GO:0051899	membrane depolarization
0.46	GO:0060073	micturition
0.44	GO:0030534	adult behavior
0.42	GO:0006812	cation transport

0.81	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.54	GO:0042166	acetylcholine binding
0.36	GO:0022850	serotonin-gated cation-selective channel activity

0.77	GO:0045211	postsynaptic membrane
0.73	GO:0030054	cell junction
0.59	GO:0005892	acetylcholine-gated channel complex

sp|P49702|ARF5_CHICK
ADP-ribosylation factor 5
Search

0.92	ADP-ribosylation factor 5

0.59	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.55	GO:0031584	activation of phospholipase D activity
0.54	GO:0060996	dendritic spine development
0.53	GO:0045176	apical protein localization
0.53	GO:0061512	protein localization to cilium
0.52	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.51	GO:0006471	protein ADP-ribosylation
0.51	GO:2000377	regulation of reactive oxygen species metabolic process
0.51	GO:0007612	learning
0.49	GO:0043066	negative regulation of apoptotic process

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0005154	epidermal growth factor receptor binding
0.35	GO:0005085	guanyl-nucleotide exchange factor activity
0.34	GO:0003924	GTPase activity
0.34	GO:0017137	Rab GTPase binding

0.52	GO:0032587	ruffle membrane
0.52	GO:0043197	dendritic spine
0.48	GO:0005794	Golgi apparatus
0.46	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0031012	extracellular matrix
0.34	GO:0070382	exocytic vesicle
0.30	GO:0016021	integral component of membrane

sp|P49705|IBP2_CHICK
Insulin-like growth factor-binding protein 2
Search

IGFBP2

0.96	Insulin like growth factor binding protein 2

0.69	GO:0001558	regulation of cell growth
0.56	GO:0042104	positive regulation of activated T cell proliferation
0.52	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.50	GO:0032868	response to insulin
0.41	GO:0032501	multicellular organismal process
0.40	GO:0048640	negative regulation of developmental growth
0.40	GO:0032502	developmental process
0.40	GO:0008156	negative regulation of DNA replication
0.40	GO:0010226	response to lithium ion
0.39	GO:0008285	negative regulation of cell proliferation

0.83	GO:0005520	insulin-like growth factor binding
0.34	GO:0005102	receptor binding
0.33	GO:0016746	transferase activity, transferring acyl groups

0.65	GO:0005576	extracellular region
0.38	GO:0016324	apical plasma membrane
0.37	GO:0031410	cytoplasmic vesicle
0.30	GO:0016021	integral component of membrane

0.33

EC:2.3

GO:0016746

sp|P49706|CCND2_CHICK
G1/S-specific cyclin-D2
Search

CCND2

0.87	G1/S-specific cyclin-D2

0.67	GO:0007049	cell cycle
0.58	GO:0071481	cellular response to X-ray
0.58	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.57	GO:1901992	positive regulation of mitotic cell cycle phase transition
0.57	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.56	GO:1902808	positive regulation of cell cycle G1/S phase transition
0.56	GO:0007616	long-term memory
0.55	GO:0008344	adult locomotory behavior
0.54	GO:0008284	positive regulation of cell proliferation
0.52	GO:0043066	negative regulation of apoptotic process

0.54	GO:0019901	protein kinase binding
0.42	GO:0070064	proline-rich region binding
0.41	GO:0042826	histone deacetylase binding
0.41	GO:0003714	transcription corepressor activity
0.40	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.39	GO:0008134	transcription factor binding
0.37	GO:0004672	protein kinase activity
0.32	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.59	GO:0097129	cyclin D2-CDK4 complex
0.50	GO:0000785	chromatin
0.49	GO:0070013	intracellular organelle lumen
0.48	GO:0005829	cytosol
0.47	GO:0012505	endomembrane system
0.45	GO:0031967	organelle envelope
0.44	GO:0031090	organelle membrane
0.41	GO:0017053	transcriptional repressor complex
0.40	GO:0005923	bicellular tight junction

0.40

GO:0016538

sp|P49707|CCNE1_CHICK
G1/S-specific cyclin-E1
Search

CCNE1

0.91

Cyclin E

0.83	GO:0000082	G1/S transition of mitotic cell cycle
0.72	GO:0051726	regulation of cell cycle
0.56	GO:0007129	synapsis
0.53	GO:0000723	telomere maintenance
0.52	GO:0000122	negative regulation of transcription by RNA polymerase II
0.51	GO:0016055	Wnt signaling pathway
0.51	GO:1903827	regulation of cellular protein localization
0.51	GO:0045859	regulation of protein kinase activity
0.51	GO:0006270	DNA replication initiation
0.45	GO:0006468	protein phosphorylation

0.54	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.52	GO:0019901	protein kinase binding
0.44	GO:0016301	kinase activity
0.35	GO:0050681	androgen receptor binding
0.34	GO:0003713	transcription coactivator activity
0.34	GO:0032403	protein complex binding

0.61	GO:0005634	nucleus
0.59	GO:0097134	cyclin E1-CDK2 complex
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.37	GO:0097135	cyclin E2-CDK2 complex
0.34	GO:0015630	microtubule cytoskeleton
0.33	GO:0005829	cytosol

0.54

GO:0016538

sp|P49708|IFNG_CHICK
Interferon gamma
Search

IFNG

0.94	Interferon gamma

0.74	GO:0006955	immune response
0.73	GO:0040008	regulation of growth
0.73	GO:0051607	defense response to virus
0.71	GO:0010469	regulation of receptor activity
0.59	GO:0070673	response to interleukin-18
0.57	GO:0042116	macrophage activation
0.49	GO:0060552	positive regulation of fructose 1,6-bisphosphate metabolic process
0.49	GO:0060549	regulation of fructose 1,6-bisphosphate 1-phosphatase activity
0.49	GO:0032834	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response
0.49	GO:2000309	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

0.86	GO:0005133	interferon-gamma receptor binding
0.76	GO:0005125	cytokine activity

0.70	GO:0005615	extracellular space
0.35	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|P49712|VATB_CHICK
V-type proton ATPase subunit B
Search

ATP6V1B1

0.72	V-type proton ATPase subunit B

0.72	GO:0015991	ATP hydrolysis coupled proton transport
0.63	GO:0007588	excretion
0.62	GO:0045851	pH reduction
0.61	GO:0042472	inner ear morphogenesis
0.60	GO:0001503	ossification
0.60	GO:0007605	sensory perception of sound
0.59	GO:0055074	calcium ion homeostasis
0.55	GO:0046034	ATP metabolic process
0.40	GO:0097401	synaptic vesicle lumen acidification
0.39	GO:0033572	transferrin transport

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0015078	hydrogen ion transmembrane transporter activity
0.40	GO:0032403	protein complex binding
0.36	GO:0016787	hydrolase activity

0.76	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.63	GO:0005902	microvillus
0.62	GO:0016328	lateral plasma membrane
0.60	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.60	GO:0016323	basolateral plasma membrane
0.60	GO:0016324	apical plasma membrane
0.52	GO:0005829	cytosol
0.45	GO:0098850	extrinsic component of synaptic vesicle membrane
0.41	GO:0070062	extracellular exosome
0.37	GO:0001726	ruffle

0.36

GO:0016787

sp|P49892|AA1R_CHICK
Adenosine receptor A1
Search

ADORA1

0.97	Adenosine receptor A1

0.85	GO:0001973	adenosine receptor signaling pathway
0.60	GO:0070256	negative regulation of mucus secretion
0.60	GO:1900453	negative regulation of long term synaptic depression
0.59	GO:0003093	regulation of glomerular filtration
0.58	GO:0051930	regulation of sensory perception of pain
0.57	GO:0002686	negative regulation of leukocyte migration
0.55	GO:0050728	negative regulation of inflammatory response
0.53	GO:0060079	excitatory postsynaptic potential
0.42	GO:0008285	negative regulation of cell proliferation
0.42	GO:0032088	negative regulation of NF-kappaB transcription factor activity

0.85	GO:0001609	G-protein coupled adenosine receptor activity
0.39	GO:0032795	heterotrimeric G-protein binding
0.37	GO:0031683	G-protein beta/gamma-subunit complex binding
0.37	GO:0001664	G-protein coupled receptor binding
0.37	GO:0004629	phospholipase C activity
0.37	GO:0031072	heat shock protein binding
0.36	GO:0046982	protein heterodimerization activity
0.35	GO:0001883	purine nucleoside binding

0.56	GO:0043197	dendritic spine
0.56	GO:0005886	plasma membrane
0.38	GO:0043195	terminal bouton
0.38	GO:0044304	main axon
0.38	GO:0014069	postsynaptic density
0.38	GO:0048786	presynaptic active zone
0.37	GO:0043025	neuronal cell body
0.37	GO:0031252	cell leading edge
0.36	GO:0005783	endoplasmic reticulum
0.34	GO:0042629	mast cell granule

sp|P50141|GCH1_CHICK
GTP cyclohydrolase 1
Search

GCH1

0.44	GTP cyclohydrolase I

0.75	GO:0046654	tetrahydrofolate biosynthetic process
0.57	GO:0014916	regulation of lung blood pressure
0.55	GO:0042416	dopamine biosynthetic process
0.55	GO:0051000	positive regulation of nitric-oxide synthase activity
0.55	GO:0010460	positive regulation of heart rate
0.54	GO:2000121	regulation of removal of superoxide radicals
0.54	GO:0050884	neuromuscular process controlling posture
0.53	GO:0046146	tetrahydrobiopterin metabolic process
0.53	GO:0034312	diol biosynthetic process
0.53	GO:0034341	response to interferon-gamma

0.79	GO:0003934	GTP cyclohydrolase I activity
0.54	GO:0051019	mitogen-activated protein kinase binding
0.49	GO:0042803	protein homodimerization activity
0.47	GO:0032550	purine ribonucleoside binding
0.47	GO:0019001	guanyl nucleotide binding
0.45	GO:0008270	zinc ion binding
0.45	GO:0003924	GTPase activity
0.41	GO:0032555	purine ribonucleotide binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0030742	GTP-dependent protein binding

0.51	GO:0031965	nuclear membrane
0.49	GO:0005737	cytoplasm
0.47	GO:0097708	intracellular vesicle
0.47	GO:0005654	nucleoplasm
0.43	GO:0043234	protein complex
0.35	GO:0044306	neuron projection terminus

0.79	EC:3.5.4.16	GO:0003934
0.79	KEGG:R00424	GO:0003934

sp|P50146|GNAI1_CHICK
Guanine nucleotide-binding protein G(i) subunit alpha-1
Search

GNAI1

0.91	Guanine nucleotide binding protein alpha inhibiting 1

0.80	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.50	GO:1904778	positive regulation of protein localization to cell cortex
0.48	GO:1904321	response to forskolin
0.48	GO:0060236	regulation of mitotic spindle organization
0.47	GO:0043949	regulation of cAMP-mediated signaling
0.46	GO:1901655	cellular response to ketone
0.45	GO:0035690	cellular response to drug
0.45	GO:0051301	cell division
0.44	GO:0071396	cellular response to lipid
0.44	GO:0071407	cellular response to organic cyclic compound

0.80	GO:0031683	G-protein beta/gamma-subunit complex binding
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.63	GO:0004871	signal transducer activity
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0031821	G-protein coupled serotonin receptor binding
0.44	GO:0032794	GTPase activating protein binding
0.40	GO:0000287	magnesium ion binding

0.51	GO:0030496	midbody
0.49	GO:0005813	centrosome
0.47	GO:1905360	GTPase complex
0.47	GO:0099738	cell cortex region
0.47	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.44	GO:0005730	nucleolus
0.42	GO:0045121	membrane raft
0.42	GO:0098797	plasma membrane protein complex
0.41	GO:0098588	bounding membrane of organelle
0.40	GO:0098791	Golgi subcompartment

sp|P50147|GNAI2_CHICK
Guanine nucleotide-binding protein G(i) subunit alpha-2
Search

GNAI2

0.91	Guanine nucleotide binding protein alpha inhibiting 2

0.81	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.51	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.49	GO:0008283	cell proliferation
0.47	GO:0051301	cell division
0.47	GO:0001973	adenosine receptor signaling pathway
0.47	GO:0007214	gamma-aminobutyric acid signaling pathway
0.42	GO:1904778	positive regulation of protein localization to cell cortex
0.41	GO:0060236	regulation of mitotic spindle organization
0.38	GO:0050805	negative regulation of synaptic transmission
0.38	GO:0007049	cell cycle

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0001664	G-protein coupled receptor binding
0.35	GO:0046872	metal ion binding

0.55	GO:0030496	midbody
0.53	GO:0005813	centrosome
0.49	GO:0030425	dendrite
0.49	GO:0044297	cell body
0.47	GO:0031981	nuclear lumen
0.46	GO:1905360	GTPase complex
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.46	GO:0005829	cytosol
0.42	GO:0098797	plasma membrane protein complex
0.40	GO:0099738	cell cortex region

sp|P50211|ISL1_CHICK
Insulin gene enhancer protein ISL-1
Search

ISL1

0.94	LIM homeodomain transcription factor islet-1

0.64	GO:0048665	neuron fate specification
0.63	GO:0021524	visceral motor neuron differentiation
0.61	GO:0048936	peripheral nervous system neuron axonogenesis
0.60	GO:0031290	retinal ganglion cell axon guidance
0.60	GO:0031016	pancreas development
0.60	GO:0060913	cardiac cell fate determination
0.59	GO:0003139	secondary heart field specification
0.58	GO:0071657	positive regulation of granulocyte colony-stimulating factor production
0.58	GO:0032730	positive regulation of interleukin-1 alpha production
0.58	GO:0045665	negative regulation of neuron differentiation

0.64	GO:0043565	sequence-specific DNA binding
0.57	GO:0043425	bHLH transcription factor binding
0.56	GO:0001105	RNA polymerase II transcription coactivator activity
0.56	GO:0001102	RNA polymerase II activating transcription factor binding
0.56	GO:0035326	enhancer binding
0.55	GO:1990841	promoter-specific chromatin binding
0.53	GO:0046872	metal ion binding
0.50	GO:0003690	double-stranded DNA binding
0.40	GO:0016922	ligand-dependent nuclear receptor binding
0.40	GO:0030331	estrogen receptor binding

0.61	GO:0005634	nucleus
0.48	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P50223|HMGX7_CHICK
Homeobox protein GHOX-7
Search

MSX1

0.90	Homeobox protein GHOX-7

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0035880	embryonic nail plate morphogenesis
0.55	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
0.53	GO:0060325	face morphogenesis
0.52	GO:2001055	positive regulation of mesenchymal cell apoptotic process
0.52	GO:0090427	activation of meiosis
0.51	GO:0030308	negative regulation of cell growth
0.51	GO:0042475	odontogenesis of dentin-containing tooth

0.64	GO:0043565	sequence-specific DNA binding
0.52	GO:0002039	p53 binding
0.49	GO:0035326	enhancer binding
0.48	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.47	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.47	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.45	GO:0070013	intracellular organelle lumen
0.41	GO:0044446	intracellular organelle part
0.34	GO:0005667	transcription factor complex

sp|P50460|CSRP2_CHICK
Cysteine and glycine-rich protein 2
Search

CSRP2

0.93	Cysteine and glycine-rich protein 2

0.39	GO:0030154	cell differentiation
0.38	GO:0032501	multicellular organismal process
0.38	GO:0048856	anatomical structure development
0.34	GO:0034109	homotypic cell-cell adhesion
0.34	GO:0007254	JNK cascade
0.34	GO:0007599	hemostasis
0.34	GO:0006937	regulation of muscle contraction
0.34	GO:0001667	ameboidal-type cell migration
0.34	GO:0042060	wound healing
0.34	GO:0001775	cell activation

0.53	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding
0.32	GO:0003723	RNA binding

0.39	GO:0005925	focal adhesion
0.39	GO:0005634	nucleus
0.37	GO:0097517	contractile actin filament bundle
0.37	GO:0042641	actomyosin
0.36	GO:0031252	cell leading edge
0.34	GO:0005861	troponin complex
0.34	GO:0070062	extracellular exosome

sp|P50478|AMPH_CHICK
Amphiphysin
Search

AMPH

0.96	LOW QUALITY PROTEIN: amphiphysin

0.37	GO:0030100	regulation of endocytosis
0.37	GO:0048488	synaptic vesicle endocytosis
0.37	GO:0007612	learning
0.35	GO:0048522	positive regulation of cellular process
0.35	GO:0007268	chemical synaptic transmission
0.35	GO:0051050	positive regulation of transport
0.34	GO:0060988	lipid tube assembly
0.34	GO:0043547	positive regulation of GTPase activity
0.34	GO:0048710	regulation of astrocyte differentiation
0.34	GO:0051647	nucleus localization

0.51	GO:0005543	phospholipid binding
0.36	GO:0005515	protein binding
0.35	GO:0044877	macromolecular complex binding

0.55	GO:0031256	leading edge membrane
0.49	GO:0005737	cytoplasm
0.42	GO:0098793	presynapse
0.41	GO:0044306	neuron projection terminus
0.40	GO:0097708	intracellular vesicle
0.39	GO:0012505	endomembrane system
0.39	GO:0012506	vesicle membrane
0.38	GO:0030054	cell junction
0.38	GO:0098805	whole membrane
0.38	GO:0098588	bounding membrane of organelle

sp|P50577|DLX5_CHICK
Homeobox protein DLX-5
Search

DLX5

0.97	Distal-less homeo box 5

0.62	GO:0060166	olfactory pit development
0.62	GO:0097376	interneuron axon guidance
0.61	GO:0021889	olfactory bulb interneuron differentiation
0.60	GO:0001958	endochondral ossification
0.59	GO:0060325	face morphogenesis
0.58	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
0.58	GO:0060021	palate development
0.58	GO:0001649	osteoblast differentiation
0.58	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.58	GO:0030509	BMP signaling pathway

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0071837	HMG box domain binding
0.56	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.51	GO:0000785	chromatin
0.49	GO:0031974	membrane-enclosed lumen
0.40	GO:0005737	cytoplasm

sp|P50593|GPC1_CHICK
Glypican-1
Search

GPC1

0.97	Glypican-1 isoform B

0.70	GO:0009966	regulation of signal transduction
0.65	GO:2001016	positive regulation of skeletal muscle cell differentiation
0.59	GO:1902724	positive regulation of skeletal muscle satellite cell proliferation
0.58	GO:0014859	negative regulation of skeletal muscle cell proliferation
0.58	GO:1902725	negative regulation of satellite cell differentiation
0.55	GO:0030200	heparan sulfate proteoglycan catabolic process
0.49	GO:0090288	negative regulation of cellular response to growth factor stimulus
0.46	GO:0023057	negative regulation of signaling
0.46	GO:0010648	negative regulation of cell communication
0.40	GO:1902727	negative regulation of growth factor dependent skeletal muscle satellite cell proliferation

0.84	GO:0043395	heparan sulfate proteoglycan binding
0.52	GO:0017134	fibroblast growth factor binding
0.51	GO:0043236	laminin binding
0.47	GO:0005507	copper ion binding
0.38	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.36	GO:0033549	MAP kinase phosphatase activity
0.35	GO:0070052	collagen V binding

0.83	GO:0046658	anchored component of plasma membrane
0.76	GO:0005578	proteinaceous extracellular matrix
0.50	GO:0045121	membrane raft
0.46	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol
0.41	GO:0005615	extracellular space
0.38	GO:0005768	endosome
0.37	GO:0005796	Golgi lumen
0.36	GO:1903561	extracellular vesicle
0.35	GO:0043202	lysosomal lumen

0.38

EC:3.1.3

GO:0008138

sp|P50594|MGN_CHICK
Protein mago nashi homolog
Search

MAGOH

0.94	Mago homolog B, exon junction complex core component

0.54	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.47	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.47	GO:0008380	RNA splicing
0.42	GO:0051028	mRNA transport
0.40	GO:0006397	mRNA processing
0.38	GO:0006417	regulation of translation
0.36	GO:0006369	termination of RNA polymerase II transcription
0.36	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.35	GO:0031123	RNA 3'-end processing
0.35	GO:0006405	RNA export from nucleus

0.38	GO:0003723	RNA binding
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.45	GO:0043234	protein complex
0.44	GO:0044446	intracellular organelle part
0.44	GO:1902494	catalytic complex
0.44	GO:0030529	intracellular ribonucleoprotein complex
0.38	GO:0043025	neuronal cell body
0.38	GO:0031974	membrane-enclosed lumen
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P50890|RSSA_CHICK
40S ribosomal protein SA
Search

RPSA

0.72	40S ribosomal protein SA

0.78	GO:0000028	ribosomal small subunit assembly
0.66	GO:0007155	cell adhesion
0.59	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.47	GO:0006407	rRNA export from nucleus
0.42	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.42	GO:0016072	rRNA metabolic process
0.37	GO:0030855	epithelial cell differentiation

0.85	GO:0005055	laminin receptor activity
0.80	GO:0043236	laminin binding
0.62	GO:0003735	structural constituent of ribosome
0.38	GO:0104005	hijacked molecular function
0.36	GO:0043022	ribosome binding
0.33	GO:0003723	RNA binding

0.74	GO:0022627	cytosolic small ribosomal subunit
0.58	GO:0005634	nucleus
0.53	GO:0005886	plasma membrane
0.45	GO:0030686	90S preribosome
0.37	GO:0005604	basement membrane
0.37	GO:0043025	neuronal cell body
0.36	GO:0070062	extracellular exosome
0.35	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.33	GO:0043233	organelle lumen

sp|P51027|NRAM1_CHICK
Natural resistance-associated macrophage protein 1
Search

SLC11A1

0.96	Natural resistance-associated macrophage protein 1

0.66	GO:0030001	metal ion transport
0.58	GO:0045342	MHC class II biosynthetic process
0.58	GO:0032632	interleukin-3 production
0.58	GO:0060586	multicellular organismal iron ion homeostasis
0.57	GO:0002309	T cell proliferation involved in immune response
0.57	GO:0006876	cellular cadmium ion homeostasis
0.56	GO:0002606	positive regulation of dendritic cell antigen processing and presentation
0.56	GO:0032623	interleukin-2 production
0.56	GO:0002369	T cell cytokine production
0.56	GO:0043091	L-arginine import

0.69	GO:0046873	metal ion transmembrane transporter activity
0.50	GO:0015491	cation:cation antiporter activity
0.49	GO:0042803	protein homodimerization activity
0.48	GO:0015299	solute:proton antiporter activity
0.42	GO:0015094	lead ion transmembrane transporter activity
0.41	GO:0046870	cadmium ion binding
0.40	GO:0072509	divalent inorganic cation transmembrane transporter activity
0.39	GO:0015295	solute:proton symporter activity

0.56	GO:0070821	tertiary granule membrane
0.55	GO:0030670	phagocytic vesicle membrane
0.53	GO:0005770	late endosome
0.52	GO:0005764	lysosome
0.52	GO:0010008	endosome membrane
0.42	GO:0070826	paraferritin complex
0.42	GO:0005886	plasma membrane
0.40	GO:0045178	basal part of cell
0.40	GO:0005903	brush border
0.39	GO:0055037	recycling endosome

sp|P51030|WNT8C_CHICK
Protein Wnt-8c
Search

sp|P51050|MTR1B_CHICK
Melatonin receptor type 1B (Fragment)
Search

0.92	Melatonin receptor type 1B

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.45	GO:0030828	positive regulation of cGMP biosynthetic process
0.45	GO:0007623	circadian rhythm
0.44	GO:0050796	regulation of insulin secretion
0.43	GO:0042593	glucose homeostasis
0.39	GO:0045820	negative regulation of glycolytic process
0.39	GO:0046325	negative regulation of glucose import
0.34	GO:0007268	chemical synaptic transmission

0.85	GO:0008502	melatonin receptor activity
0.46	GO:0042562	hormone binding
0.36	GO:0033218	amide binding
0.35	GO:0097159	organic cyclic compound binding
0.34	GO:0008144	drug binding
0.33	GO:0005515	protein binding
0.33	GO:1901363	heterocyclic compound binding

0.43	GO:0043235	receptor complex
0.41	GO:0005887	integral component of plasma membrane

sp|P51417|RL15_CHICK
60S ribosomal protein L15 (Fragment)
Search

RPL15

0.65	Ribosomal protein L15

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.37	GO:0045471	response to ethanol
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis

0.64	GO:0003735	structural constituent of ribosome
0.47	GO:0045296	cadherin binding
0.40	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.44	GO:0044445	cytosolic part
0.40	GO:0005634	nucleus
0.40	GO:0044446	intracellular organelle part
0.38	GO:0031672	A band
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.32

GO:0016787

sp|P51475|OPSP_CHICK
Pinopsin
Search

RH1

0.44	Deep brain photoreceptor protein pinopsin

0.79	GO:0007602	phototransduction
0.78	GO:0007601	visual perception
0.75	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.48	GO:0016038	absorption of visible light
0.44	GO:0009584	detection of visible light
0.41	GO:0071482	cellular response to light stimulus

0.79	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.36	GO:0016918	retinal binding

0.43	GO:0043005	neuron projection
0.41	GO:0043204	perikaryon
0.41	GO:0044441	ciliary part
0.41	GO:0097731	9+0 non-motile cilium
0.39	GO:0042599	lamellar body
0.37	GO:0005815	microtubule organizing center
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0031253	cell projection membrane
0.34	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0098805	whole membrane

sp|P51509|RELB_CHICK
Transcription factor RelB homolog
Search

RELB

0.96	V-rel avian reticuloendotheliosis viral oncogene homolog B

0.61	GO:0006357	regulation of transcription by RNA polymerase II
0.59	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.57	GO:0038061	NIK/NF-kappaB signaling
0.55	GO:0045063	T-helper 1 cell differentiation
0.55	GO:0032688	negative regulation of interferon-beta production
0.54	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.54	GO:0043011	myeloid dendritic cell differentiation
0.53	GO:0010628	positive regulation of gene expression
0.53	GO:0032922	circadian regulation of gene expression
0.50	GO:0045892	negative regulation of transcription, DNA-templated

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.53	GO:0001067	regulatory region nucleic acid binding
0.50	GO:0019901	protein kinase binding
0.48	GO:0042802	identical protein binding
0.47	GO:0003682	chromatin binding
0.35	GO:0003714	transcription corepressor activity
0.34	GO:0071532	ankyrin repeat binding
0.34	GO:0051059	NF-kappaB binding
0.34	GO:0070491	repressing transcription factor binding

0.63	GO:0071159	NF-kappaB complex
0.61	GO:0005634	nucleus
0.52	GO:0033256	I-kappaB/NF-kappaB complex
0.49	GO:0005813	centrosome
0.49	GO:0005829	cytosol
0.45	GO:0070013	intracellular organelle lumen
0.35	GO:0042627	chylomicron
0.33	GO:0005667	transcription factor complex
0.33	GO:0000785	chromatin
0.30	GO:0016020	membrane

sp|P51641|CNTFR_CHICK
Ciliary neurotrophic factor receptor subunit alpha
Search

CNTFR

0.97	Ciliary neurotrophic factor receptor subunit alpha

0.77	GO:0019221	cytokine-mediated signaling pathway
0.60	GO:0003360	brainstem development
0.58	GO:0001967	suckling behavior
0.56	GO:0043524	negative regulation of neuron apoptotic process
0.55	GO:0060538	skeletal muscle organ development
0.54	GO:0007548	sex differentiation
0.53	GO:0008284	positive regulation of cell proliferation
0.42	GO:0048680	positive regulation of axon regeneration

0.79	GO:0004896	cytokine receptor activity
0.55	GO:0019955	cytokine binding
0.50	GO:0005102	receptor binding

0.60	GO:0097059	CNTFR-CLCF1 complex
0.60	GO:0070110	ciliary neurotrophic factor receptor complex
0.54	GO:0016324	apical plasma membrane
0.41	GO:0031225	anchored component of membrane
0.34	GO:0019898	extrinsic component of membrane

sp|P51887|FMOD_CHICK
Fibromodulin
Search

FMOD

0.97	Fibromodulin

0.56	GO:0030199	collagen fibril organization
0.47	GO:0007409	axonogenesis
0.47	GO:0061303	cornea development in camera-type eye
0.37	GO:0042340	keratan sulfate catabolic process
0.37	GO:0018146	keratan sulfate biosynthetic process
0.36	GO:0007181	transforming growth factor beta receptor complex assembly
0.35	GO:0042476	odontogenesis
0.34	GO:0042060	wound healing
0.34	GO:0007601	visual perception

0.34	GO:0005518	collagen binding
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0032561	guanyl ribonucleotide binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0005578	proteinaceous extracellular matrix
0.54	GO:0005615	extracellular space
0.36	GO:0043202	lysosomal lumen
0.36	GO:0005796	Golgi lumen
0.32	GO:1903561	extracellular vesicle

sp|P51890|LUM_CHICK
Lumican
Search

LUM

0.97	Keratan sulfate proteoglycan lumican

0.83	GO:0030199	collagen fibril organization
0.75	GO:0007601	visual perception
0.57	GO:0032914	positive regulation of transforming growth factor beta1 production
0.49	GO:0045944	positive regulation of transcription by RNA polymerase II
0.46	GO:0007409	axonogenesis
0.43	GO:0048596	embryonic camera-type eye morphogenesis
0.37	GO:0051216	cartilage development
0.37	GO:0070848	response to growth factor
0.36	GO:0014070	response to organic cyclic compound
0.35	GO:0042340	keratan sulfate catabolic process

0.55	GO:0005518	collagen binding
0.34	GO:0005201	extracellular matrix structural constituent
0.34	GO:0004016	adenylate cyclase activity
0.34	GO:0016301	kinase activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0000287	magnesium ion binding
0.33	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.74	GO:0005578	proteinaceous extracellular matrix
0.53	GO:0044420	extracellular matrix component
0.51	GO:0005581	collagen trimer
0.51	GO:0005615	extracellular space
0.48	GO:0099512	supramolecular fiber
0.36	GO:1903561	extracellular vesicle
0.35	GO:0043202	lysosomal lumen
0.35	GO:0005796	Golgi lumen
0.31	GO:0005887	integral component of plasma membrane

0.34

EC:4.6.1.1

GO:0004016

sp|P51901|ANXA6_CHICK
Annexin A6
Search

ANXA6

0.60

Annexin

0.58	GO:0051560	mitochondrial calcium ion homeostasis
0.55	GO:0006937	regulation of muscle contraction
0.55	GO:0097190	apoptotic signaling pathway
0.53	GO:0006816	calcium ion transport
0.53	GO:0051260	protein homooligomerization
0.45	GO:0034220	ion transmembrane transport
0.37	GO:0051283	negative regulation of sequestering of calcium ion
0.36	GO:0001778	plasma membrane repair
0.36	GO:0009888	tissue development
0.36	GO:0048513	animal organ development

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.57	GO:0048306	calcium-dependent protein binding
0.55	GO:0015485	cholesterol binding
0.52	GO:0015276	ligand-gated ion channel activity
0.51	GO:0042803	protein homodimerization activity
0.47	GO:0032550	purine ribonucleoside binding
0.47	GO:0019001	guanyl nucleotide binding
0.41	GO:0032555	purine ribonucleotide binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0031902	late endosome membrane
0.54	GO:0005765	lysosomal membrane
0.53	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0005739	mitochondrion
0.41	GO:0042470	melanosome
0.38	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome
0.36	GO:0042584	chromaffin granule membrane
0.35	GO:0014704	intercalated disc
0.35	GO:0034704	calcium channel complex

sp|P51903|PGK_CHICK
Phosphoglycerate kinase
Search

PGK1

0.47	Phosphoglycerate kinase

0.70	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.51	GO:0001666	response to hypoxia
0.48	GO:0031639	plasminogen activation
0.46	GO:1903862	positive regulation of oxidative phosphorylation
0.46	GO:0036294	cellular response to decreased oxygen levels
0.46	GO:0016525	negative regulation of angiogenesis
0.45	GO:0030855	epithelial cell differentiation

0.79	GO:0004618	phosphoglycerate kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0047134	protein-disulfide reductase activity
0.33	GO:0005515	protein binding

0.45	GO:0045121	membrane raft
0.43	GO:0005615	extracellular space
0.37	GO:0035686	sperm fibrous sheath
0.36	GO:1903561	extracellular vesicle
0.35	GO:0005829	cytosol
0.33	GO:0005694	chromosome

0.79	EC:2.7.2.3	GO:0004618
0.79	KEGG:R01512	GO:0004618

sp|P51913|ENOA_CHICK
Alpha-enolase
Search

ENO1

0.72	Alpha-enolase

0.71	GO:0006096	glycolytic process
0.51	GO:1903297	regulation of hypoxia-induced intrinsic apoptotic signaling pathway
0.50	GO:0010756	positive regulation of plasminogen activation
0.50	GO:0061718	glucose catabolic process to pyruvate
0.50	GO:2001171	positive regulation of ATP biosynthetic process
0.50	GO:0006735	NADH regeneration
0.50	GO:1900038	negative regulation of cellular response to hypoxia
0.49	GO:0045933	positive regulation of muscle contraction
0.48	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.48	GO:0030308	negative regulation of cell growth

0.78	GO:0004634	phosphopyruvate hydratase activity
0.64	GO:0000287	magnesium ion binding
0.48	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0045296	cadherin binding
0.46	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.45	GO:0042803	protein homodimerization activity
0.45	GO:0051020	GTPase binding
0.37	GO:0046982	protein heterodimerization activity
0.35	GO:0003723	RNA binding
0.35	GO:0005212	structural constituent of eye lens

0.77	GO:0000015	phosphopyruvate hydratase complex
0.48	GO:0099738	cell cortex region
0.45	GO:0009986	cell surface
0.40	GO:0005886	plasma membrane
0.39	GO:0043209	myelin sheath
0.37	GO:0019898	extrinsic component of membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0097458	neuron part
0.35	GO:0031430	M band
0.34	GO:0044297	cell body

0.78

EC:4.2.1.11

GO:0004634

sp|P51971|EIF1_CHICK
Eukaryotic translation initiation factor 1 (Fragment)
Search

EIF1

0.93	Eukaryotic translation initiation factor 1

0.72	GO:0006413	translational initiation
0.47	GO:0006446	regulation of translational initiation
0.43	GO:0009048	dosage compensation by inactivation of X chromosome
0.34	GO:0006886	intracellular protein transport

0.73	GO:0003743	translation initiation factor activity
0.35	GO:0017137	Rab GTPase binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0016787	hydrolase activity

0.41	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.32

GO:0016787

sp|P52162|MAX_CHICK
Protein max
Search

MAX

0.96	MYC associated factor X

0.52

GO:0000122

negative regulation of transcription by RNA polymerase II

0.68	GO:0046983	protein dimerization activity
0.57	GO:0070888	E-box binding
0.55	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding
0.55	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0042802	identical protein binding

0.82	GO:0071339	MLL1 complex
0.76	GO:0090575	RNA polymerase II transcription factor complex
0.51	GO:0000790	nuclear chromatin
0.49	GO:0032993	protein-DNA complex

sp|P52186|KCNJ2_CHICK
Inward rectifier potassium channel 2
Search

KCNJ2

0.84	Inward rectifier potassium channel

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.62	GO:0014861	regulation of skeletal muscle contraction via regulation of action potential
0.62	GO:0090076	relaxation of skeletal muscle
0.61	GO:0098655	cation transmembrane transport
0.60	GO:0055119	relaxation of cardiac muscle
0.60	GO:0086013	membrane repolarization during cardiac muscle cell action potential
0.59	GO:0086002	cardiac muscle cell action potential involved in contraction
0.58	GO:0086091	regulation of heart rate by cardiac conduction
0.58	GO:0051289	protein homotetramerization

0.84	GO:0005242	inward rectifier potassium channel activity
0.60	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
0.57	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.51	GO:0042802	identical protein binding
0.34	GO:0005086	ARF guanyl-nucleotide exchange factor activity

0.53	GO:0008076	voltage-gated potassium channel complex
0.39	GO:0005790	smooth endoplasmic reticulum
0.39	GO:0030315	T-tubule
0.39	GO:0014704	intercalated disc
0.39	GO:0043197	dendritic spine
0.38	GO:0005791	rough endoplasmic reticulum
0.38	GO:0043025	neuronal cell body
0.37	GO:0005794	Golgi apparatus

sp|P52550|MYBA_CHICK
Myb-related protein A
Search

MYBL1

0.97	MYB proto-oncogene like 1

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0051254	positive regulation of RNA metabolic process
0.53	GO:0010557	positive regulation of macromolecule biosynthetic process
0.53	GO:0031328	positive regulation of cellular biosynthetic process
0.52	GO:0006366	transcription by RNA polymerase II
0.46	GO:0000278	mitotic cell cycle
0.46	GO:0030154	cell differentiation
0.40	GO:1990511	piRNA biosynthetic process

0.55	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.33	GO:0071987	WD40-repeat domain binding

0.42	GO:0005634	nucleus
0.33	GO:0000785	chromatin
0.32	GO:0005829	cytosol
0.31	GO:0043233	organelle lumen

sp|P52731|PDE6C_CHICK
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'
Search

PDE6C

0.56	Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'

0.62	GO:0060041	retina development in camera-type eye
0.61	GO:0007165	signal transduction
0.59	GO:0048593	camera-type eye morphogenesis
0.56	GO:0042462	eye photoreceptor cell development
0.55	GO:0009583	detection of light stimulus
0.55	GO:0007601	visual perception
0.46	GO:0051480	regulation of cytosolic calcium ion concentration
0.46	GO:0045494	photoreceptor cell maintenance
0.44	GO:0046037	GMP metabolic process
0.43	GO:0048598	embryonic morphogenesis

0.79	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.54	GO:0046872	metal ion binding
0.39	GO:0030553	cGMP binding

0.45	GO:0001750	photoreceptor outer segment
0.36	GO:0060170	ciliary membrane

0.79

EC:3.1.4.17

GO:0004114

sp|P52802|EFNA2_CHICK
Ephrin-A2
Search

0.83	GO:0048013	ephrin receptor signaling pathway
0.53	GO:0030316	osteoclast differentiation
0.53	GO:0046849	bone remodeling
0.49	GO:0007411	axon guidance
0.43	GO:0090109	regulation of cell-substrate junction assembly
0.43	GO:1903391	regulation of adherens junction organization
0.43	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading
0.43	GO:0071372	cellular response to follicle-stimulating hormone stimulus
0.43	GO:0050919	negative chemotaxis
0.43	GO:0048672	positive regulation of collateral sprouting

0.85	GO:0046875	ephrin receptor binding
0.43	GO:0005169	neurotrophin TRKB receptor binding
0.43	GO:0045499	chemorepellent activity
0.34	GO:0016301	kinase activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0003723	RNA binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0031225	anchored component of membrane
0.43	GO:0031233	intrinsic component of external side of plasma membrane
0.41	GO:0005604	basement membrane
0.40	GO:0005912	adherens junction
0.39	GO:0043204	perikaryon
0.39	GO:0031594	neuromuscular junction
0.34	GO:0005901	caveola
0.30	GO:0016021	integral component of membrane

0.33

GO:0016773

sp|P52804|EFNA5_CHICK
Ephrin-A5
Search

0.92	Putative ephrin ligand for eph receptor tyrosine kinase

0.83	GO:0048013	ephrin receptor signaling pathway
0.56	GO:0071372	cellular response to follicle-stimulating hormone stimulus
0.56	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading
0.56	GO:0048672	positive regulation of collateral sprouting
0.56	GO:0048668	collateral sprouting
0.56	GO:1904321	response to forskolin
0.56	GO:0051893	regulation of focal adhesion assembly
0.55	GO:0031290	retinal ganglion cell axon guidance
0.55	GO:0050919	negative chemotaxis
0.54	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus

0.85	GO:0046875	ephrin receptor binding
0.58	GO:0005169	neurotrophin TRKB receptor binding
0.56	GO:0045499	chemorepellent activity
0.36	GO:0005170	neurotrophin TRKC receptor binding
0.36	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.36	GO:0005168	neurotrophin TRKA receptor binding
0.35	GO:0016301	kinase activity
0.34	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
0.33	GO:0008168	methyltransferase activity

0.56	GO:0031362	anchored component of external side of plasma membrane
0.52	GO:0005604	basement membrane
0.51	GO:0005912	adherens junction
0.38	GO:0005901	caveola
0.30	GO:0016021	integral component of membrane

0.34

EC:1.14.11

GO:0016706

sp|P53033|RFC2_CHICK
Replication factor C subunit 2
Search

RFC2

0.87	Replication factor C subunit 2

0.66	GO:0006260	DNA replication
0.55	GO:1900264	positive regulation of DNA-directed DNA polymerase activity
0.42	GO:0006281	DNA repair
0.35	GO:0042769	DNA damage response, detection of DNA damage
0.35	GO:1901796	regulation of signal transduction by p53 class mediator
0.34	GO:0000723	telomere maintenance
0.34	GO:0022402	cell cycle process
0.33	GO:0006310	DNA recombination
0.33	GO:0019725	cellular homeostasis
0.33	GO:0071897	DNA biosynthetic process

0.56	GO:0003689	DNA clamp loader activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0043142	single-stranded DNA-dependent ATPase activity
0.47	GO:0019899	enzyme binding

0.56	GO:0005663	DNA replication factor C complex
0.52	GO:0031390	Ctf18 RFC-like complex
0.41	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen

sp|P53352|INCE_CHICK
Inner centromere protein
Search

INCENP

0.90	Inner centromere protein A

0.77	GO:0000281	mitotic cytokinesis
0.72	GO:0007059	chromosome segregation
0.48	GO:0051225	spindle assembly
0.40	GO:0016925	protein sumoylation
0.38	GO:0031110	regulation of microtubule polymerization or depolymerization
0.37	GO:0051276	chromosome organization
0.35	GO:0006518	peptide metabolic process
0.34	GO:0043604	amide biosynthetic process
0.34	GO:1901566	organonitrogen compound biosynthetic process
0.34	GO:0010467	gene expression

0.48	GO:0005515	protein binding
0.35	GO:0003735	structural constituent of ribosome

0.82	GO:0005721	pericentric heterochromatin
0.82	GO:0030496	midbody
0.77	GO:0000776	kinetochore
0.77	GO:0000801	central element
0.76	GO:0005819	spindle
0.76	GO:0000800	lateral element
0.75	GO:0010369	chromocenter
0.69	GO:0016604	nuclear body
0.62	GO:0005829	cytosol
0.59	GO:0000779	condensed chromosome, centromeric region

sp|P53410|ISL2_CHICK
Insulin gene enhancer protein ISL-2 (Fragment)
Search

ISL2

0.91	Insulin gene enhancer protein ISL-2

0.62	GO:0048665	neuron fate specification
0.60	GO:0021524	visceral motor neuron differentiation
0.58	GO:0007409	axonogenesis
0.58	GO:0097485	neuron projection guidance
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0045665	negative regulation of neuron differentiation
0.50	GO:0031017	exocrine pancreas development
0.48	GO:1990138	neuron projection extension

0.65	GO:0043565	sequence-specific DNA binding
0.53	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.61

GO:0005634

nucleus

sp|P53411|LHX1_CHICK
LIM/homeobox protein Lhx1
Search

LHX1

0.94	LIM homeobox protein 1

0.67	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation
0.66	GO:0021527	spinal cord association neuron differentiation
0.66	GO:0021702	cerebellar Purkinje cell differentiation
0.62	GO:0030900	forebrain development
0.61	GO:2000744	positive regulation of anterior head development
0.61	GO:0097477	lateral motor column neuron migration
0.61	GO:2000768	positive regulation of nephron tubule epithelial cell differentiation
0.61	GO:0061205	paramesonephric duct development
0.60	GO:0072049	comma-shaped body morphogenesis
0.60	GO:0035847	uterine epithelium development

0.64	GO:0043565	sequence-specific DNA binding
0.54	GO:0046872	metal ion binding
0.45	GO:0003700	DNA binding transcription factor activity
0.44	GO:0003714	transcription corepressor activity
0.35	GO:0035326	enhancer binding
0.35	GO:0005515	protein binding
0.34	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.44	GO:0043234	protein complex

sp|P53412|LHX3_CHICK
LIM/homeobox protein Lhx3
Search

LHX3

0.94	Lim homeobox protein 3 splice variant

0.72	GO:0021526	medial motor column neuron differentiation
0.67	GO:0008045	motor neuron axon guidance
0.64	GO:0021521	ventral spinal cord interneuron specification
0.63	GO:0001890	placenta development
0.61	GO:0043066	negative regulation of apoptotic process
0.60	GO:0021527	spinal cord association neuron differentiation
0.60	GO:0021520	spinal cord motor neuron cell fate specification
0.59	GO:0045944	positive regulation of transcription by RNA polymerase II
0.59	GO:0021983	pituitary gland development
0.57	GO:0048839	inner ear development

0.63	GO:0043565	sequence-specific DNA binding
0.57	GO:0001085	RNA polymerase II transcription factor binding
0.56	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.54	GO:0046872	metal ion binding
0.51	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.53	GO:0005667	transcription factor complex

sp|P53413|LMX1B_CHICK
LIM/homeobox protein LMX-1.2
Search

LMX1B

0.95	LIM homeobox transcription factor 1 beta

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0030902	hindbrain development
0.53	GO:0071542	dopaminergic neuron differentiation
0.52	GO:0030901	midbrain development
0.52	GO:0042048	olfactory behavior
0.52	GO:0021542	dentate gyrus development
0.51	GO:0007613	memory
0.51	GO:0021953	central nervous system neuron differentiation

0.63	GO:0043565	sequence-specific DNA binding
0.53	GO:0046872	metal ion binding
0.49	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.49	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0003690	double-stranded DNA binding
0.40	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding
0.35	GO:0005515	protein binding

0.60

GO:0005634

nucleus

sp|P53449|ALDOC_CHICK
Fructose-bisphosphate aldolase C (Fragment)
Search

ALDOC

0.20	Fructose-bisphosphate aldolase

0.70	GO:0006096	glycolytic process
0.57	GO:0030388	fructose 1,6-bisphosphate metabolic process
0.51	GO:0030855	epithelial cell differentiation
0.43	GO:0006000	fructose metabolic process
0.43	GO:0046716	muscle cell cellular homeostasis
0.43	GO:0007339	binding of sperm to zona pellucida
0.42	GO:0006941	striated muscle contraction
0.39	GO:0051289	protein homotetramerization
0.39	GO:0006754	ATP biosynthetic process
0.39	GO:0008360	regulation of cell shape

0.78	GO:0004332	fructose-bisphosphate aldolase activity
0.50	GO:0008092	cytoskeletal protein binding
0.45	GO:0070061	fructose binding
0.42	GO:0045296	cadherin binding
0.36	GO:0042802	identical protein binding
0.36	GO:0002020	protease binding
0.35	GO:0061609	fructose-1-phosphate aldolase activity
0.34	GO:0051117	ATPase binding
0.33	GO:0003723	RNA binding
0.33	GO:0004672	protein kinase activity

0.44	GO:0061827	sperm head
0.44	GO:0005739	mitochondrion
0.43	GO:0070062	extracellular exosome
0.40	GO:0005829	cytosol
0.40	GO:0015629	actin cytoskeleton
0.39	GO:0031430	M band
0.39	GO:0035686	sperm fibrous sheath
0.38	GO:0031674	I band
0.37	GO:1904724	tertiary granule lumen
0.37	GO:1904813	ficolin-1-rich granule lumen

0.78

EC:4.1.2.13

GO:0004332

sp|P53478|ACT5_CHICK
Actin, cytoplasmic type 5
Search

ACTB

0.60	Cytoplasmic actin

0.41	GO:0098974	postsynaptic actin cytoskeleton organization
0.40	GO:0072749	cellular response to cytochalasin B
0.40	GO:0032091	negative regulation of protein binding
0.39	GO:0045214	sarcomere organization
0.39	GO:0071346	cellular response to interferon-gamma
0.37	GO:0070527	platelet aggregation
0.36	GO:0048870	cell motility
0.36	GO:0001895	retina homeostasis
0.35	GO:0021762	substantia nigra development
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis

0.51	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0098973	structural constituent of postsynaptic actin cytoskeleton
0.41	GO:0030957	Tat protein binding
0.41	GO:0042802	identical protein binding
0.41	GO:0050998	nitric-oxide synthase binding
0.41	GO:0005522	profilin binding
0.40	GO:0019894	kinesin binding
0.39	GO:0031625	ubiquitin protein ligase binding

0.65	GO:0097433	dense body
0.61	GO:0005925	focal adhesion
0.54	GO:0005856	cytoskeleton
0.46	GO:0005886	plasma membrane
0.42	GO:0043209	myelin sheath
0.40	GO:0070062	extracellular exosome
0.39	GO:0035267	NuA4 histone acetyltransferase complex
0.39	GO:0044448	cell cortex part
0.38	GO:0036464	cytoplasmic ribonucleoprotein granule
0.38	GO:0045335	phagocytic vesicle

sp|P53488|ARP2_CHICK
Actin-related protein 2
Search

ACTR2

0.85	Actin-related protein 2 isoform a

0.81	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.54	GO:0016344	meiotic chromosome movement towards spindle pole
0.52	GO:0033206	meiotic cytokinesis
0.51	GO:0071346	cellular response to interferon-gamma
0.51	GO:0008356	asymmetric cell division
0.51	GO:0051653	spindle localization
0.50	GO:0060271	cilium assembly
0.49	GO:0016482	cytosolic transport
0.49	GO:0007163	establishment or maintenance of cell polarity
0.40	GO:0035984	cellular response to trichostatin A

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0003779	actin binding
0.49	GO:0005200	structural constituent of cytoskeleton
0.48	GO:0032403	protein complex binding

0.80	GO:0005885	Arp2/3 protein complex
0.53	GO:0030478	actin cap
0.45	GO:0005829	cytosol
0.41	GO:0061825	podosome core
0.40	GO:0042995	cell projection
0.38	GO:0014069	postsynaptic density
0.38	GO:0031252	cell leading edge
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen

sp|P53545|GSC_CHICK
Homeobox protein goosecoid
Search

GSC

0.96	Homeobox protein goosecoid

0.63	GO:0014036	neural crest cell fate specification
0.60	GO:0042474	middle ear morphogenesis
0.59	GO:0023019	signal transduction involved in regulation of gene expression
0.59	GO:0021904	dorsal/ventral neural tube patterning
0.57	GO:0048644	muscle organ morphogenesis
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0048704	embryonic skeletal system morphogenesis
0.55	GO:0030178	negative regulation of Wnt signaling pathway
0.55	GO:0030900	forebrain development

0.64	GO:0043565	sequence-specific DNA binding
0.58	GO:0001103	RNA polymerase II repressing transcription factor binding
0.56	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.33	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.52	GO:0005667	transcription factor complex
0.49	GO:0043233	organelle lumen
0.44	GO:0044446	intracellular organelle part

0.33

EC:3.5.4.4

GO:0004000

sp|P53666|LIMK2_CHICK
LIM domain kinase 2
Search

LIMK2

0.97	LIM domain kinase 2

0.62	GO:0006468	protein phosphorylation
0.51	GO:0007283	spermatogenesis
0.40	GO:0035556	intracellular signal transduction
0.36	GO:0042325	regulation of phosphorylation
0.34	GO:0007281	germ cell development

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.48	GO:0046982	protein heterodimerization activity
0.40	GO:0004871	signal transducer activity

0.52	GO:0005801	cis-Golgi network
0.44	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm

sp|P53760|LCAT_CHICK
Phosphatidylcholine-sterol acyltransferase (Fragment)
Search

LCAT

0.78	Phosphatidylcholine-sterol acyltransferase

0.67	GO:0034435	cholesterol esterification
0.65	GO:0034372	very-low-density lipoprotein particle remodeling
0.65	GO:0034375	high-density lipoprotein particle remodeling
0.64	GO:0043691	reverse cholesterol transport
0.64	GO:0090107	regulation of high-density lipoprotein particle assembly
0.62	GO:0008203	cholesterol metabolic process
0.62	GO:0042632	cholesterol homeostasis
0.61	GO:0006656	phosphatidylcholine biosynthetic process
0.54	GO:0042158	lipoprotein biosynthetic process
0.36	GO:0051384	response to glucocorticoid

0.71	GO:0008374	O-acyltransferase activity
0.66	GO:0034186	apolipoprotein A-I binding
0.36	GO:0004623	phospholipase A2 activity

0.63	GO:0034364	high-density lipoprotein particle
0.38	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.71

GO:0008374

sp|P54097|TECTB_CHICK
Beta-tectorin
Search

TECTB

0.97	Beta-tectorin

0.37	GO:0048840	otolith development
0.36	GO:0006501	C-terminal protein lipidation
0.35	GO:0007605	sensory perception of sound

0.59	GO:0005201	extracellular matrix structural constituent
0.33	GO:0016874	ligase activity

0.64	GO:0005576	extracellular region
0.39	GO:0031225	anchored component of membrane
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

GO:0016874

sp|P54755|EPHA5_CHICK
Ephrin type-A receptor 5
Search

EPHA5

0.81	EPH receptor A5

0.83	GO:0048013	ephrin receptor signaling pathway
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.69	GO:0071372	cellular response to follicle-stimulating hormone stimulus
0.68	GO:1904321	response to forskolin
0.66	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus
0.66	GO:0021766	hippocampus development
0.65	GO:1901655	cellular response to ketone
0.62	GO:0007411	axon guidance
0.62	GO:0035690	cellular response to drug
0.62	GO:0071396	cellular response to lipid

0.84	GO:0005003	ephrin receptor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.64	GO:0005887	integral component of plasma membrane
0.61	GO:0005912	adherens junction
0.41	GO:0005769	early endosome

sp|P54939|TLN1_CHICK
Talin-1
Search

TLN1

0.88

Talin

0.84	GO:0007016	cytoskeletal anchoring at plasma membrane
0.72	GO:0007155	cell adhesion
0.55	GO:0033622	integrin activation
0.54	GO:0007044	cell-substrate junction assembly
0.52	GO:0030866	cortical actin cytoskeleton organization
0.50	GO:0007229	integrin-mediated signaling pathway
0.47	GO:0061386	closure of optic fissure
0.45	GO:0055013	cardiac muscle cell development
0.45	GO:0045214	sarcomere organization
0.37	GO:0030168	platelet activation

0.78	GO:0051015	actin filament binding
0.76	GO:0005200	structural constituent of cytoskeleton
0.55	GO:0017166	vinculin binding
0.54	GO:0030274	LIM domain binding
0.54	GO:0001786	phosphatidylserine binding
0.53	GO:0005178	integrin binding
0.51	GO:0045296	cadherin binding
0.49	GO:0035091	phosphatidylinositol binding
0.34	GO:0000062	fatty-acyl-CoA binding

0.82	GO:0001726	ruffle
0.81	GO:0005925	focal adhesion
0.68	GO:0005856	cytoskeleton
0.38	GO:0031256	leading edge membrane
0.38	GO:0031253	cell projection membrane
0.37	GO:0070062	extracellular exosome
0.37	GO:0009986	cell surface
0.35	GO:0045202	synapse
0.35	GO:0005916	fascia adherens
0.35	GO:0005829	cytosol

sp|P55024|TYRO_CHICK
Tyrosinase
Search

TYR

0.61	Truncated tyrosinase

0.58	GO:0042438	melanin biosynthetic process
0.56	GO:0048538	thymus development
0.54	GO:0043473	pigmentation
0.52	GO:0008283	cell proliferation
0.52	GO:0055114	oxidation-reduction process
0.41	GO:0033280	response to vitamin D
0.40	GO:0051591	response to cAMP
0.39	GO:0009411	response to UV
0.36	GO:0006570	tyrosine metabolic process
0.35	GO:0042416	dopamine biosynthetic process

0.67	GO:0004503	monophenol monooxygenase activity
0.54	GO:0046872	metal ion binding
0.51	GO:0042803	protein homodimerization activity
0.51	GO:0046982	protein heterodimerization activity
0.35	GO:0004097	catechol oxidase activity

0.57	GO:0042470	melanosome
0.53	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0090741	pigment granule membrane
0.43	GO:0045009	chitosome
0.42	GO:0043231	intracellular membrane-bounded organelle
0.40	GO:0030659	cytoplasmic vesicle membrane
0.39	GO:0098805	whole membrane
0.37	GO:0005829	cytosol
0.34	GO:0005798	Golgi-associated vesicle
0.30	GO:0016021	integral component of membrane

0.67

EC:1.14.18.1

GO:0004503

sp|P55080|MFAP1_CHICK
Microfibrillar-associated protein 1
Search

MFAP1

0.90	Microfibril associated protein 1

0.86

GO:0001527

microfibril

sp|P55164|CRBA2_CHICK
Beta-crystallin A2
Search

CRYBA2

0.97	Beta-crystallin A2

0.66	GO:0002088	lens development in camera-type eye
0.52	GO:0007601	visual perception
0.37	GO:2000210	positive regulation of anoikis
0.37	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling
0.36	GO:0051898	negative regulation of protein kinase B signaling
0.36	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.36	GO:0032007	negative regulation of TOR signaling
0.36	GO:0001818	negative regulation of cytokine production

0.67	GO:0005212	structural constituent of eye lens
0.59	GO:0042803	protein homodimerization activity

0.34	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P55165|CRBB3_CHICK
Beta-crystallin B3
Search

CRYBB3

0.97	Beta-crystallin B3

0.71	GO:0007601	visual perception
0.34	GO:0006468	protein phosphorylation
0.33	GO:0002088	lens development in camera-type eye
0.33	GO:0007165	signal transduction

0.78	GO:0005212	structural constituent of eye lens
0.36	GO:0047696	beta-adrenergic receptor kinase activity
0.35	GO:0004703	G-protein coupled receptor kinase activity
0.34	GO:0005515	protein binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.36

EC:2.7.11.15

GO:0047696

sp|P55166|PAX9_CHICK
Paired box protein Pax-9 (Fragment)
Search

PAX9

0.93	Paired box transcription factor

0.76	GO:0009887	animal organ morphogenesis
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0042481	regulation of odontogenesis
0.56	GO:0060325	face morphogenesis
0.55	GO:0007492	endoderm development
0.52	GO:0071363	cellular response to growth factor stimulus
0.50	GO:1902680	positive regulation of RNA biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.51	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0005310	dicarboxylic acid transmembrane transporter activity
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex
0.33	GO:0005743	mitochondrial inner membrane
0.30	GO:0016021	integral component of membrane

sp|P55167|MSHR_CHICK
Melanocyte-stimulating hormone receptor
Search

MC1R

0.69	Melanocyte-stimulating hormone receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:0090037	positive regulation of protein kinase C signaling
0.35	GO:0010739	positive regulation of protein kinase A signaling
0.35	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0042438	melanin biosynthetic process
0.35	GO:0019233	sensory perception of pain
0.35	GO:0051897	positive regulation of protein kinase B signaling
0.34	GO:0043473	pigmentation
0.34	GO:0045893	positive regulation of transcription, DNA-templated
0.34	GO:0045892	negative regulation of transcription, DNA-templated

0.85	GO:0004980	melanocyte-stimulating hormone receptor activity
0.33	GO:0003700	DNA binding transcription factor activity

0.55	GO:0005886	plasma membrane
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P55168|CCNC_CHICK
Cyclin-C
Search

CCNC

0.90

Cyclin-C

0.76	GO:0045859	regulation of protein kinase activity
0.49	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain
0.47	GO:0072015	glomerular visceral epithelial cell development
0.46	GO:0045787	positive regulation of cell cycle
0.46	GO:0033674	positive regulation of kinase activity
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:0090209	negative regulation of triglyceride metabolic process
0.34	GO:0036211	protein modification process
0.33	GO:0016310	phosphorylation

0.82	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.34	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0016301	kinase activity
0.33	GO:0005515	protein binding
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.77	GO:0016592	mediator complex
0.47	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.34	GO:0000151	ubiquitin ligase complex
0.30	GO:0016020	membrane

0.82

GO:0016538

sp|P55169|CCND1_CHICK
G1/S-specific cyclin-D1
Search

CCND1

0.97	G1/S-specific cyclin-D1

0.67	GO:0007049	cell cycle
0.57	GO:0070141	response to UV-A
0.57	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.56	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.56	GO:1901992	positive regulation of mitotic cell cycle phase transition
0.56	GO:0044783	G1 DNA damage checkpoint
0.55	GO:0071157	negative regulation of cell cycle arrest
0.55	GO:1902807	negative regulation of cell cycle G1/S phase transition
0.54	GO:0033601	positive regulation of mammary gland epithelial cell proliferation
0.54	GO:0097421	liver regeneration

0.54	GO:0070064	proline-rich region binding
0.52	GO:0003714	transcription corepressor activity
0.52	GO:0042826	histone deacetylase binding
0.52	GO:0019901	protein kinase binding
0.51	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.47	GO:0008134	transcription factor binding
0.44	GO:0004672	protein kinase activity
0.38	GO:0032403	protein complex binding
0.35	GO:0060089	molecular transducer activity

0.61	GO:0005634	nucleus
0.56	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.52	GO:0017053	transcriptional repressor complex
0.50	GO:0005923	bicellular tight junction
0.47	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.39	GO:0005829	cytosol
0.38	GO:0005694	chromosome
0.38	GO:0012505	endomembrane system
0.36	GO:0031090	organelle membrane

0.51

GO:0016538

sp|P55806|NRT1_CHICK
NAD(P)(+)--arginine ADP-ribosyltransferase 1
Search

ART1

0.75	T-cell ecto-ADP-ribosyltransferase 1

0.84	GO:0006471	protein ADP-ribosylation
0.39	GO:0046677	response to antibiotic
0.37	GO:0019677	NAD catabolic process
0.35	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0018195	peptidyl-arginine modification

0.85	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity
0.52	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.37	GO:0061810	NAD glycohydrolase activity
0.35	GO:0004984	olfactory receptor activity

0.50	GO:0031225	anchored component of membrane
0.48	GO:0009986	cell surface
0.43	GO:0044194	cytolytic granule
0.39	GO:0005615	extracellular space
0.38	GO:0033017	sarcoplasmic reticulum membrane
0.35	GO:0031226	intrinsic component of plasma membrane
0.33	GO:0098552	side of membrane
0.30	GO:0016021	integral component of membrane

0.85

EC:2.4.2.31

GO:0003956

sp|P55807|NRT2_CHICK
NAD(P)(+)--arginine ADP-ribosyltransferase 2
Search

ART1

0.75	Erythroblast NAD(P)(+)--arginine ADP-ribosyltransferase

0.84	GO:0006471	protein ADP-ribosylation
0.38	GO:0046677	response to antibiotic
0.36	GO:0019677	NAD catabolic process
0.34	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0018195	peptidyl-arginine modification

0.85	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity
0.51	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.36	GO:0061810	NAD glycohydrolase activity
0.34	GO:0004984	olfactory receptor activity

0.49	GO:0031225	anchored component of membrane
0.47	GO:0009986	cell surface
0.42	GO:0044194	cytolytic granule
0.38	GO:0005615	extracellular space
0.38	GO:0033017	sarcoplasmic reticulum membrane
0.35	GO:0031226	intrinsic component of plasma membrane
0.33	GO:0098552	side of membrane
0.30	GO:0016021	integral component of membrane

0.85

EC:2.4.2.31

GO:0003956

sp|P55878|GLI1_CHICK
Zinc finger protein GLI1 (Fragment)
Search

GLI1

0.92	Zinc finger protein GLI1 isoform B

0.84	GO:0007224	smoothened signaling pathway
0.79	GO:0008284	positive regulation of cell proliferation
0.73	GO:0045893	positive regulation of transcription, DNA-templated
0.42	GO:0030154	cell differentiation
0.42	GO:0007275	multicellular organism development
0.39	GO:2000345	regulation of hepatocyte proliferation
0.39	GO:0021936	regulation of cerebellar granule cell precursor proliferation
0.39	GO:0055023	positive regulation of cardiac muscle tissue growth
0.39	GO:0060043	regulation of cardiac muscle cell proliferation
0.39	GO:0060033	anatomical structure regression

0.55	GO:0003677	DNA binding
0.44	GO:0003682	chromatin binding
0.38	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.37	GO:0046872	metal ion binding
0.37	GO:0001067	regulatory region nucleic acid binding
0.37	GO:0008017	microtubule binding

0.39	GO:0005634	nucleus
0.39	GO:0097542	ciliary tip
0.39	GO:0097546	ciliary base
0.38	GO:0005930	axoneme
0.36	GO:0005829	cytosol
0.36	GO:0043233	organelle lumen

sp|P55879|GLI2_CHICK
Zinc finger protein GLI2 (Fragment)
Search

0.57	zinc finger protein GLI2

0.50	GO:0021508	floor plate formation
0.48	GO:0021983	pituitary gland development
0.48	GO:0048566	embryonic digestive tract development
0.48	GO:0021522	spinal cord motor neuron differentiation
0.48	GO:0021532	neural tube patterning
0.47	GO:0048546	digestive tract morphogenesis
0.47	GO:0001708	cell fate specification
0.47	GO:0022612	gland morphogenesis
0.47	GO:0060032	notochord regression
0.47	GO:0007224	smoothened signaling pathway

0.51	GO:0003676	nucleic acid binding
0.47	GO:1990841	promoter-specific chromatin binding
0.44	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.41	GO:0008134	transcription factor binding
0.39	GO:0008270	zinc ion binding

0.46	GO:0005929	cilium
0.43	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.43	GO:0016607	nuclear speck
0.41	GO:0005730	nucleolus
0.40	GO:0044430	cytoskeletal part
0.37	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P55968|PO4F1_CHICK
POU domain, class 4, transcription factor 1 (Fragment)
Search

0.58	POU domain, class 4, transcription factor 2

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0045672	positive regulation of osteoclast differentiation
0.49	GO:0050885	neuromuscular process controlling balance
0.49	GO:0031175	neuron projection development
0.47	GO:0007600	sensory perception
0.47	GO:0071345	cellular response to cytokine stimulus
0.46	GO:0051254	positive regulation of RNA metabolic process

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0003714	transcription corepressor activity
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003682	chromatin binding
0.44	GO:0035326	enhancer binding
0.44	GO:0003690	double-stranded DNA binding
0.43	GO:0003713	transcription coactivator activity
0.42	GO:0003697	single-stranded DNA binding
0.41	GO:0051020	GTPase binding

0.61	GO:0005634	nucleus
0.43	GO:0070013	intracellular organelle lumen
0.42	GO:0043005	neuron projection
0.41	GO:0000785	chromatin
0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P56517|HDAC1_CHICK
Histone deacetylase 1
Search

HDAC1

0.52	Histone deacetylase

0.79	GO:0016575	histone deacetylation
0.55	GO:0006346	methylation-dependent chromatin silencing
0.55	GO:0010870	positive regulation of receptor biosynthetic process
0.54	GO:0006351	transcription, DNA-templated
0.54	GO:0043922	negative regulation by host of viral transcription
0.54	GO:0060766	negative regulation of androgen receptor signaling pathway
0.52	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.51	GO:0042127	regulation of cell proliferation
0.49	GO:0000122	negative regulation of transcription by RNA polymerase II
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II

0.80	GO:0004407	histone deacetylase activity
0.73	GO:0034979	NAD-dependent protein deacetylase activity
0.54	GO:0051059	NF-kappaB binding
0.54	GO:0001103	RNA polymerase II repressing transcription factor binding
0.53	GO:0001106	RNA polymerase II transcription corepressor activity
0.52	GO:0046872	metal ion binding
0.52	GO:0047485	protein N-terminus binding
0.52	GO:0033613	activating transcription factor binding
0.52	GO:0002039	p53 binding
0.52	GO:0042826	histone deacetylase binding

0.57	GO:0005634	nucleus
0.51	GO:0017053	transcriptional repressor complex
0.47	GO:0000785	chromatin
0.45	GO:0005829	cytosol
0.45	GO:0070013	intracellular organelle lumen
0.45	GO:1904949	ATPase complex
0.42	GO:0043025	neuronal cell body
0.42	GO:0043234	protein complex
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0043005	neuron projection

0.80

GO:0004407

sp|P56519|HDAC2_CHICK
Histone deacetylase 2
Search

HDAC2

0.51	Histone deacetylase

0.79	GO:0016575	histone deacetylation
0.56	GO:0010870	positive regulation of receptor biosynthetic process
0.55	GO:0006344	maintenance of chromatin silencing
0.54	GO:0006351	transcription, DNA-templated
0.52	GO:0043433	negative regulation of DNA binding transcription factor activity
0.51	GO:0008284	positive regulation of cell proliferation
0.51	GO:0000122	negative regulation of transcription by RNA polymerase II
0.50	GO:0045862	positive regulation of proteolysis
0.49	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:0050769	positive regulation of neurogenesis

0.80	GO:0004407	histone deacetylase activity
0.73	GO:0034979	NAD-dependent protein deacetylase activity
0.55	GO:0051059	NF-kappaB binding
0.55	GO:0001103	RNA polymerase II repressing transcription factor binding
0.54	GO:0042826	histone deacetylase binding
0.53	GO:0046872	metal ion binding
0.45	GO:0043565	sequence-specific DNA binding
0.39	GO:0044212	transcription regulatory region DNA binding
0.38	GO:1990841	promoter-specific chromatin binding
0.38	GO:0035851	Krueppel-associated box domain binding

0.57	GO:0005634	nucleus
0.52	GO:0017053	transcriptional repressor complex
0.50	GO:0034708	methyltransferase complex
0.48	GO:0000785	chromatin
0.46	GO:0070013	intracellular organelle lumen
0.46	GO:1904949	ATPase complex
0.43	GO:0043234	protein complex
0.38	GO:0005737	cytoplasm
0.36	GO:0005657	replication fork

0.80

GO:0004407

sp|P56520|HDAC3_CHICK
Histone deacetylase 3
Search

HDAC3

0.51	Histone deacetylase

0.80	GO:0016575	histone deacetylation
0.60	GO:1903507	negative regulation of nucleic acid-templated transcription
0.58	GO:0071498	cellular response to fluid shear stress
0.57	GO:0042993	positive regulation of transcription factor import into nucleus
0.56	GO:0046329	negative regulation of JNK cascade
0.54	GO:0051225	spindle assembly
0.54	GO:0032008	positive regulation of TOR signaling
0.53	GO:0031647	regulation of protein stability
0.53	GO:0006351	transcription, DNA-templated
0.52	GO:0006355	regulation of transcription, DNA-templated

0.81	GO:0004407	histone deacetylase activity
0.70	GO:0034979	NAD-dependent protein deacetylase activity
0.67	GO:0003714	transcription corepressor activity
0.57	GO:0051059	NF-kappaB binding
0.55	GO:0042826	histone deacetylase binding
0.54	GO:0030332	cyclin binding
0.53	GO:0003682	chromatin binding
0.52	GO:0046872	metal ion binding
0.35	GO:0070491	repressing transcription factor binding
0.34	GO:0051020	GTPase binding

0.56	GO:0005634	nucleus
0.55	GO:0017053	transcriptional repressor complex
0.54	GO:0005876	spindle microtubule
0.49	GO:0005794	Golgi apparatus
0.48	GO:0005829	cytosol
0.47	GO:0070013	intracellular organelle lumen
0.42	GO:0005886	plasma membrane
0.35	GO:1902494	catalytic complex
0.34	GO:0000785	chromatin
0.30	GO:0016021	integral component of membrane

0.81

GO:0004407

sp|P56673|PITX1_CHICK
Pituitary homeobox 1
Search

PITX1

0.87	Pituitary homeobox 1

0.68	GO:0007275	multicellular organism development
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0048625	myoblast fate commitment
0.55	GO:0010468	regulation of gene expression
0.55	GO:0060322	head development
0.54	GO:0014706	striated muscle tissue development
0.52	GO:0006366	transcription by RNA polymerase II
0.52	GO:0061448	connective tissue development
0.51	GO:0009653	anatomical structure morphogenesis

0.62	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.56	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.55	GO:0001085	RNA polymerase II transcription factor binding
0.52	GO:0044212	transcription regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.44	GO:0033613	activating transcription factor binding
0.43	GO:0031490	chromatin DNA binding
0.42	GO:0003713	transcription coactivator activity
0.42	GO:0001104	RNA polymerase II transcription cofactor activity

0.61	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.45	GO:0070013	intracellular organelle lumen
0.42	GO:0043232	intracellular non-membrane-bounded organelle
0.41	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|P56732|AVR2_CHICK
Avidin-related protein 2
Search

0.85

Avidin

0.51	GO:0015878	biotin transport
0.49	GO:0019731	antibacterial humoral response

0.58

GO:0009374

biotin binding

0.66

GO:0005576

extracellular region

sp|P56733|AVR3_CHICK
Avidin-related protein 3
Search

0.86

Avidin

0.49	GO:0019731	antibacterial humoral response
0.49	GO:0015878	biotin transport

0.57

GO:0009374

biotin binding

0.66	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|P56734|AVR4_CHICK
Avidin-related protein 4/5
Search

0.91

Avidin

0.51	GO:0019731	antibacterial humoral response
0.49	GO:0015878	biotin transport

0.57

GO:0009374

biotin binding

0.66

GO:0005576

extracellular region

sp|P56735|AVR6_CHICK
Avidin-related protein 6
Search

0.86

Avidin

0.50	GO:0015878	biotin transport
0.50	GO:0019731	antibacterial humoral response

0.57

GO:0009374

biotin binding

0.66

GO:0005576

extracellular region

sp|P56736|AVR7_CHICK
Avidin-related protein 7
Search

0.87

Avidin

0.49	GO:0015878	biotin transport
0.49	GO:0019731	antibacterial humoral response

0.57

GO:0009374

biotin binding

0.66	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|P57074|SOX8_CHICK
Transcription factor SOX-8
Search

SOX8

0.97	Sex determining region Y-box 8

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.61	GO:0072289	metanephric nephron tubule formation
0.61	GO:0060221	retinal rod cell differentiation
0.61	GO:0072034	renal vesicle induction
0.59	GO:0072197	ureter morphogenesis
0.59	GO:0046533	negative regulation of photoreceptor cell differentiation
0.59	GO:0060008	Sertoli cell differentiation
0.59	GO:0060018	astrocyte fate commitment
0.59	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
0.58	GO:0045662	negative regulation of myoblast differentiation

0.73	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.56	GO:0001046	core promoter sequence-specific DNA binding
0.51	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.50	GO:0046982	protein heterodimerization activity
0.49	GO:0008134	transcription factor binding
0.41	GO:0035326	enhancer binding
0.40	GO:0003682	chromatin binding
0.38	GO:0034236	protein kinase A catalytic subunit binding
0.38	GO:0097157	pre-mRNA intronic binding
0.37	GO:0008013	beta-catenin binding

0.61	GO:0005634	nucleus
0.50	GO:0005667	transcription factor complex
0.43	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm
0.35	GO:0070013	intracellular organelle lumen
0.30	GO:0016020	membrane

sp|P57788|MOT4_CHICK
Monocarboxylate transporter 4
Search

SLC16A3

0.95	Monocarboxylic acid transporter 4

0.81	GO:0035873	lactate transmembrane transport
0.34	GO:0050900	leukocyte migration
0.33	GO:0006090	pyruvate metabolic process

0.81	GO:0015129	lactate transmembrane transporter activity
0.37	GO:0015293	symporter activity
0.33	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.67	GO:0005887	integral component of plasma membrane
0.54	GO:0031965	nuclear membrane

sp|P58267|DPF1_CHICK
Zinc finger protein neuro-d4
Search

DPF1

0.83	Double PHD fingers 1

0.53	GO:0048731	system development
0.41	GO:0014706	striated muscle tissue development
0.41	GO:0061061	muscle structure development
0.40	GO:0048729	tissue morphogenesis
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:2001141	regulation of RNA biosynthetic process
0.36	GO:0010468	regulation of gene expression

0.63	GO:0008270	zinc ion binding
0.50	GO:0003676	nucleic acid binding

0.85	GO:0071565	nBAF complex
0.42	GO:0005654	nucleoplasm

sp|P58268|REQU_CHICK
Zinc finger protein ubi-d4
Search

DPF2

0.95	Double PHD fingers 2

0.54	GO:0046872	metal ion binding
0.47	GO:0003676	nucleic acid binding

0.54	GO:0005813	centrosome
0.50	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.37	GO:0000790	nuclear chromatin

sp|P58270|DPF3_CHICK
Zinc finger protein DPF3
Search

DPF3

0.87	Double PHD fingers 3

0.58	GO:0048731	system development
0.46	GO:0014706	striated muscle tissue development
0.46	GO:0061061	muscle structure development
0.45	GO:0048729	tissue morphogenesis
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:2001141	regulation of RNA biosynthetic process
0.38	GO:0010468	regulation of gene expression

0.62	GO:0008270	zinc ion binding
0.49	GO:0003676	nucleic acid binding

0.83	GO:0071565	nBAF complex
0.52	GO:0005654	nucleoplasm

sp|P59101|SCX_CHICK
Basic helix-loop-helix transcription factor scleraxis
Search

0.97	Basic helix-loop-helix transcription factor scleraxis

0.54	GO:0007498	mesoderm development
0.54	GO:0061053	somite development
0.53	GO:0048705	skeletal system morphogenesis
0.53	GO:0060485	mesenchyme development
0.52	GO:0007517	muscle organ development
0.52	GO:0048729	tissue morphogenesis
0.52	GO:0035989	tendon development
0.51	GO:0043009	chordate embryonic development
0.51	GO:0035993	deltoid tuberosity development
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II

0.68	GO:0046983	protein dimerization activity
0.53	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.49	GO:0043425	bHLH transcription factor binding
0.47	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.46	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.46	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0003729	mRNA binding

0.51	GO:0005667	transcription factor complex
0.45	GO:0005634	nucleus
0.39	GO:0044446	intracellular organelle part

sp|P60706|ACTB_CHICK
Actin, cytoplasmic 1
Search

ACTB

0.64	Beta-actin variant 2

0.53	GO:0098974	postsynaptic actin cytoskeleton organization
0.52	GO:0072749	cellular response to cytochalasin B
0.49	GO:0032091	negative regulation of protein binding
0.46	GO:0045214	sarcomere organization
0.46	GO:0071346	cellular response to interferon-gamma
0.44	GO:0048870	cell motility
0.39	GO:0070527	platelet aggregation
0.39	GO:0001895	retina homeostasis
0.37	GO:0021762	substantia nigra development
0.37	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis

0.53	GO:0098973	structural constituent of postsynaptic actin cytoskeleton
0.51	GO:0030554	adenyl nucleotide binding
0.51	GO:0030957	Tat protein binding
0.51	GO:0050998	nitric-oxide synthase binding
0.50	GO:0097367	carbohydrate derivative binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0008144	drug binding
0.50	GO:0042802	identical protein binding
0.49	GO:0019894	kinesin binding
0.49	GO:0005522	profilin binding

0.75	GO:0097433	dense body
0.70	GO:0005925	focal adhesion
0.61	GO:0005856	cytoskeleton
0.53	GO:0043209	myelin sheath
0.50	GO:0005886	plasma membrane
0.47	GO:0035267	NuA4 histone acetyltransferase complex
0.47	GO:0036464	cytoplasmic ribonucleoprotein granule
0.47	GO:0070062	extracellular exosome
0.46	GO:0044448	cell cortex part
0.45	GO:0005829	cytosol

sp|P60878|SNP25_CHICK
Synaptosomal-associated protein 25
Search

SNAP25

0.78	Synaptosomal-associated protein 25-A

0.85	GO:1990926	short-term synaptic potentiation
0.84	GO:0099590	neurotransmitter receptor internalization
0.84	GO:0098881	exocytic insertion of neurotransmitter receptor to plasma membrane
0.83	GO:0031915	positive regulation of synaptic plasticity
0.83	GO:0098969	neurotransmitter receptor transport to postsynaptic membrane
0.79	GO:0060291	long-term synaptic potentiation
0.79	GO:0099643	signal release from synapse
0.79	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.78	GO:0008306	associative learning
0.78	GO:0007626	locomotory behavior

0.85	GO:0017075	syntaxin-1 binding
0.57	GO:0005484	SNAP receptor activity

0.86	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
0.80	GO:0031083	BLOC-1 complex
0.78	GO:0042734	presynaptic membrane
0.75	GO:0043209	myelin sheath
0.74	GO:0008021	synaptic vesicle
0.73	GO:0043005	neuron projection
0.73	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.73	GO:0005802	trans-Golgi network
0.72	GO:0036477	somatodendritic compartment
0.72	GO:0048471	perinuclear region of cytoplasm

sp|P61355|RL27_CHICK
60S ribosomal protein L27
Search

RPL27

0.75	60S ribosomal protein L27

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.44	GO:0030218	erythrocyte differentiation
0.42	GO:0016072	rRNA metabolic process
0.42	GO:0042254	ribosome biogenesis
0.35	GO:1904044	response to aldosterone
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.63	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.47	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.44	GO:0044445	cytosolic part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus

0.32

GO:0016787

sp|P61798|APTX_CHICK
Aprataxin (Fragment)
Search

APTX

0.92

Aprataxin

0.65	GO:0006281	DNA repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.52	GO:0042542	response to hydrogen peroxide
0.50	GO:0031647	regulation of protein stability
0.48	GO:0006266	DNA ligation
0.46	GO:0016311	dephosphorylation

0.85	GO:0033699	DNA 5'-adenosine monophosphate hydrolase activity
0.55	GO:0003677	DNA binding
0.53	GO:0047485	protein N-terminus binding
0.52	GO:0051219	phosphoprotein binding
0.51	GO:0008967	phosphoglycolate phosphatase activity
0.49	GO:0003682	chromatin binding
0.49	GO:0003725	double-stranded RNA binding
0.48	GO:0120108	DNA-3'-diphospho-5'-guanosine diphosphatase
0.38	GO:0046403	polynucleotide 3'-phosphatase activity
0.36	GO:0046872	metal ion binding

0.50	GO:0005730	nucleolus
0.49	GO:0005654	nucleoplasm
0.48	GO:0000790	nuclear chromatin
0.32	GO:0005737	cytoplasm

0.51	EC:3.1.3.18	GO:0008967
0.51	KEGG:R01334	GO:0008967

sp|P62149|CALM_CHICK
Calmodulin
Search

0.50	Calmodulin 1 (phosphorylase kinase, delta)

0.41	GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity
0.41	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity
0.40	GO:0005513	detection of calcium ion
0.40	GO:0032516	positive regulation of phosphoprotein phosphatase activity
0.40	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.40	GO:0030819	positive regulation of cAMP biosynthetic process
0.39	GO:0055117	regulation of cardiac muscle contraction
0.39	GO:0002027	regulation of heart rate
0.39	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
0.38	GO:0043388	positive regulation of DNA binding

0.70	GO:0005509	calcium ion binding
0.41	GO:0031997	N-terminal myristoylation domain binding
0.40	GO:0031432	titin binding
0.40	GO:0008179	adenylate cyclase binding
0.40	GO:0072542	protein phosphatase activator activity
0.40	GO:0097718	disordered domain specific binding
0.39	GO:0044325	ion channel binding
0.39	GO:0019855	calcium channel inhibitor activity
0.38	GO:0019901	protein kinase binding
0.35	GO:0016301	kinase activity

0.40	GO:0034703	cation channel complex
0.39	GO:0000922	spindle pole
0.39	GO:0005876	spindle microtubule
0.39	GO:0030017	sarcomere
0.38	GO:0005813	centrosome
0.38	GO:0043209	myelin sheath
0.36	GO:0005887	integral component of plasma membrane
0.35	GO:1902494	catalytic complex
0.35	GO:0043234	protein complex
0.33	GO:0005829	cytosol

sp|P62167|NCS1_CHICK
Neuronal calcium sensor 1
Search

NCS1

0.96	neuronal calcium sensor 1

0.43	GO:1905949	negative regulation of calcium ion import across plasma membrane
0.43	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.42	GO:0048731	system development
0.41	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.41	GO:0010446	response to alkaline pH
0.41	GO:0051960	regulation of nervous system development
0.41	GO:0060284	regulation of cell development
0.41	GO:0048522	positive regulation of cellular process
0.41	GO:0070588	calcium ion transmembrane transport
0.40	GO:0007635	chemosensory behavior

0.70	GO:0005509	calcium ion binding
0.44	GO:0098744	1-phosphatidylinositol 4-kinase activator activity
0.42	GO:0005245	voltage-gated calcium channel activity
0.38	GO:0019901	protein kinase binding
0.36	GO:0000287	magnesium ion binding
0.35	GO:0008427	calcium-dependent protein kinase inhibitor activity
0.35	GO:0016301	kinase activity

0.52	GO:0036477	somatodendritic compartment
0.50	GO:0030424	axon
0.48	GO:0120038	plasma membrane bounded cell projection part
0.43	GO:0005794	Golgi apparatus
0.42	GO:0005886	plasma membrane
0.41	GO:0014069	postsynaptic density
0.40	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0044297	cell body
0.40	GO:0031045	dense core granule
0.40	GO:0030054	cell junction

sp|P62207|PP1B_CHICK
Serine/threonine-protein phosphatase PP1-beta catalytic subunit
Search

PPP1CB

0.49	Serine/threonine-protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.51	GO:0042752	regulation of circadian rhythm
0.49	GO:0030155	regulation of cell adhesion
0.46	GO:0032922	circadian regulation of gene expression
0.46	GO:0009648	photoperiodism
0.46	GO:0060028	convergent extension involved in axis elongation
0.41	GO:0005977	glycogen metabolic process
0.41	GO:0001889	liver development
0.40	GO:0009605	response to external stimulus
0.39	GO:0051301	cell division

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.57	GO:0050115	myosin-light-chain-phosphatase activity
0.54	GO:0046872	metal ion binding
0.48	GO:0019901	protein kinase binding
0.42	GO:0046982	protein heterodimerization activity

0.85	GO:0072357	PTW/PP1 phosphatase complex
0.84	GO:0000164	protein phosphatase type 1 complex
0.49	GO:0000784	nuclear chromosome, telomeric region
0.45	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.39	GO:0005730	nucleolus
0.39	GO:0005654	nucleoplasm
0.37	GO:0042587	glycogen granule
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome

0.57

EC:3.1.3.53

GO:0050115

sp|P62303|RUXE_CHICK
Small nuclear ribonucleoprotein E
Search

SNRPE

0.84	Small nuclear ribonucleoprotein polypeptide E

0.74	GO:0000398	mRNA splicing, via spliceosome
0.46	GO:0022618	ribonucleoprotein complex assembly
0.44	GO:0042633	hair cycle
0.36	GO:0008334	histone mRNA metabolic process
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0051170	nuclear import

0.37	GO:0003723	RNA binding
0.36	GO:1990446	U1 snRNP binding
0.33	GO:0005515	protein binding

0.75	GO:0005681	spliceosomal complex
0.63	GO:0019013	viral nucleocapsid
0.51	GO:0005687	U4 snRNP
0.49	GO:0005682	U5 snRNP
0.49	GO:0005685	U1 snRNP
0.49	GO:0005686	U2 snRNP
0.48	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.46	GO:0034709	methylosome
0.46	GO:0034715	pICln-Sm protein complex
0.46	GO:0034719	SMN-Sm protein complex

sp|P62597|POTE1_CHICK
Protection of telomeres protein 1
Search

POT1

0.95	Protection of telomeres protein 1

0.77	GO:0000723	telomere maintenance
0.61	GO:0060383	positive regulation of DNA strand elongation
0.61	GO:1905464	positive regulation of DNA duplex unwinding
0.59	GO:0032202	telomere assembly
0.59	GO:0051974	negative regulation of telomerase activity
0.59	GO:0070200	establishment of protein localization to telomere
0.59	GO:0051096	positive regulation of helicase activity
0.58	GO:1905774	regulation of DNA helicase activity
0.58	GO:0032210	regulation of telomere maintenance via telomerase
0.57	GO:0051973	positive regulation of telomerase activity

0.84	GO:0043047	single-stranded telomeric DNA binding
0.61	GO:1990955	G-rich single-stranded DNA binding
0.60	GO:0010521	telomerase inhibitor activity
0.60	GO:1905773	8-hydroxy-2'-deoxyguanosine DNA binding
0.60	GO:0061821	telomeric D-loop binding
0.58	GO:0017151	DEAD/H-box RNA helicase binding
0.41	GO:0061849	telomeric G-quadruplex DNA binding
0.36	GO:0017137	Rab GTPase binding

0.78	GO:0000784	nuclear chromosome, telomeric region
0.58	GO:0000782	telomere cap complex
0.37	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P62758|NCALD_CHICK
Neurocalcin-delta
Search

NCALD

0.92	Kv channel-interacting protein 1

0.53	GO:0003073	regulation of systemic arterial blood pressure
0.53	GO:0019722	calcium-mediated signaling
0.42	GO:0032879	regulation of localization
0.42	GO:0048731	system development
0.42	GO:0071277	cellular response to calcium ion
0.41	GO:0061387	regulation of extent of cell growth
0.41	GO:0032409	regulation of transporter activity
0.40	GO:0010769	regulation of cell morphogenesis involved in differentiation
0.40	GO:0050920	regulation of chemotaxis
0.40	GO:0048638	regulation of developmental growth

0.70	GO:0005509	calcium ion binding
0.52	GO:0030276	clathrin binding
0.51	GO:0003779	actin binding
0.49	GO:0015631	tubulin binding
0.39	GO:0042802	identical protein binding
0.34	GO:0015276	ligand-gated ion channel activity

0.37	GO:0005622	intracellular
0.36	GO:0070062	extracellular exosome
0.34	GO:0012506	vesicle membrane
0.34	GO:0048475	coated membrane
0.34	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0012505	endomembrane system
0.33	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P62764|VISL1_CHICK
Visinin-like protein 1
Search

VSNL1

0.95	Visinin like 1

0.55	GO:0046676	negative regulation of insulin secretion
0.55	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
0.54	GO:0045921	positive regulation of exocytosis
0.42	GO:0065009	regulation of molecular function
0.40	GO:0007165	signal transduction
0.34	GO:0007417	central nervous system development

0.70	GO:0005509	calcium ion binding
0.48	GO:0005246	calcium channel regulator activity
0.34	GO:0008022	protein C-terminus binding
0.34	GO:0019904	protein domain specific binding

0.47	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P62801|H4_CHICK
Histone H4
Search

sp|P62846|RS15_CHICK
40S ribosomal protein S15
Search

RPS15

0.69	Ribosomal protein S15

0.58	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.46	GO:0000028	ribosomal small subunit assembly
0.43	GO:0043009	chordate embryonic development
0.38	GO:0000056	ribosomal small subunit export from nucleus
0.37	GO:0097421	liver regeneration
0.37	GO:0001649	osteoblast differentiation
0.36	GO:0016072	rRNA metabolic process

0.62	GO:0003735	structural constituent of ribosome
0.56	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.67	GO:0015935	small ribosomal subunit
0.45	GO:0022626	cytosolic ribosome
0.36	GO:0005925	focal adhesion
0.36	GO:0005654	nucleoplasm
0.36	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane

sp|P62985|RL40_CHICK
Ubiquitin-60S ribosomal protein L40 (Fragment)
Search

UBA52

0.45	Ubiquitin A-52 residue ribosomal protein fusion product 1

0.60	GO:0006518	peptide metabolic process
0.60	GO:0043604	amide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:1901566	organonitrogen compound biosynthetic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.40	GO:0009949	polarity specification of anterior/posterior axis
0.38	GO:0017085	response to insecticide
0.36	GO:0006301	postreplication repair
0.36	GO:0007623	circadian rhythm

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0031386	protein tag
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.46	GO:0005829	cytosol
0.44	GO:0005654	nucleoplasm
0.44	GO:0005783	endoplasmic reticulum
0.39	GO:0005886	plasma membrane
0.37	GO:0043209	myelin sheath
0.37	GO:0005765	lysosomal membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0030666	endocytic vesicle membrane

sp|P63247|RACK1_CHICK
Receptor of activated protein C kinase 1
Search

0.82	Guanine nucleotide-binding protein beta subunit

0.70	GO:0033123	positive regulation of purine nucleotide catabolic process
0.70	GO:0030807	positive regulation of cyclic nucleotide catabolic process
0.70	GO:1903208	negative regulation of hydrogen peroxide-induced neuron death
0.69	GO:0030820	regulation of cAMP catabolic process
0.69	GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity
0.67	GO:0032464	positive regulation of protein homooligomerization
0.67	GO:0051901	positive regulation of mitochondrial depolarization
0.66	GO:0050765	negative regulation of phagocytosis
0.66	GO:2000543	positive regulation of gastrulation
0.66	GO:0042998	positive regulation of Golgi to plasma membrane protein transport

0.68	GO:0030292	protein tyrosine kinase inhibitor activity
0.66	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.65	GO:0042169	SH2 domain binding
0.65	GO:0005080	protein kinase C binding
0.64	GO:0030971	receptor tyrosine kinase binding
0.62	GO:0035591	signaling adaptor activity
0.62	GO:0019903	protein phosphatase binding
0.61	GO:0030332	cyclin binding
0.60	GO:0045296	cadherin binding
0.57	GO:0043022	ribosome binding

0.68	GO:1990630	IRE1-RACK1-PP2A complex
0.65	GO:0001891	phagocytic cup
0.62	GO:0030496	midbody
0.60	GO:0048471	perinuclear region of cytoplasm
0.57	GO:0005654	nucleoplasm
0.56	GO:0043025	neuronal cell body
0.56	GO:0005829	cytosol
0.54	GO:0030425	dendrite
0.48	GO:0005739	mitochondrion
0.44	GO:0070062	extracellular exosome

sp|P63270|ACTH_CHICK
Actin, gamma-enteric smooth muscle
Search

ACTG2

0.96	Smooth muscle alpha actin

0.81	GO:0090131	mesenchyme migration
0.65	GO:0010628	positive regulation of gene expression
0.42	GO:0072144	glomerular mesangial cell development
0.42	GO:0006936	muscle contraction
0.41	GO:0008015	blood circulation
0.39	GO:0009615	response to virus
0.39	GO:0003015	heart process
0.38	GO:0035296	regulation of tube diameter
0.38	GO:0003018	vascular process in circulatory system
0.38	GO:0061869	regulation of hepatic stellate cell migration

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0019901	protein kinase binding
0.35	GO:0005200	structural constituent of cytoskeleton

0.75	GO:0030175	filopodium
0.74	GO:0030027	lamellipodium
0.72	GO:0044297	cell body
0.54	GO:0032982	myosin filament
0.46	GO:0005737	cytoplasm
0.41	GO:0070062	extracellular exosome
0.39	GO:0072562	blood microparticle
0.39	GO:0097517	contractile actin filament bundle
0.39	GO:0042641	actomyosin
0.38	GO:0071944	cell periphery

sp|P63283|UBC9_CHICK
SUMO-conjugating enzyme UBC9
Search

UBE2I

0.76	SUMO-conjugating enzyme UBC9-B

0.80	GO:0016925	protein sumoylation
0.48	GO:1903755	positive regulation of SUMO transferase activity
0.46	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.45	GO:0000122	negative regulation of transcription by RNA polymerase II
0.44	GO:0007059	chromosome segregation
0.42	GO:0051301	cell division
0.42	GO:0007049	cell cycle
0.38	GO:0060216	definitive hemopoiesis
0.36	GO:0042359	vitamin D metabolic process
0.36	GO:0061484	hematopoietic stem cell homeostasis

0.82	GO:0019789	SUMO transferase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0043398	HLH domain binding
0.48	GO:0071535	RING-like zinc finger domain binding
0.47	GO:0044388	small protein activating enzyme binding
0.46	GO:0061650	ubiquitin-like protein conjugating enzyme activity
0.44	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0061630	ubiquitin protein ligase activity

0.48	GO:1990356	sumoylated E2 ligase complex
0.45	GO:0016605	PML body
0.41	GO:0005829	cytosol
0.41	GO:1990234	transferase complex
0.37	GO:0005635	nuclear envelope
0.36	GO:0000795	synaptonemal complex
0.36	GO:0001650	fibrillar center
0.35	GO:0030425	dendrite
0.35	GO:0045202	synapse

0.35

GO:0016874

sp|P67869|CSK2B_CHICK
Casein kinase II subunit beta
Search

CSNK2B

0.59	Casein kinase II subunit beta

0.76	GO:0045859	regulation of protein kinase activity
0.54	GO:0033211	adiponectin-activated signaling pathway
0.53	GO:0032927	positive regulation of activin receptor signaling pathway
0.53	GO:0061154	endothelial tube morphogenesis
0.52	GO:0043537	negative regulation of blood vessel endothelial cell migration
0.52	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.51	GO:0018107	peptidyl-threonine phosphorylation
0.41	GO:0016055	Wnt signaling pathway
0.38	GO:0097421	liver regeneration
0.38	GO:0033574	response to testosterone

0.79	GO:0019887	protein kinase regulator activity
0.52	GO:0016301	kinase activity
0.48	GO:0003682	chromatin binding
0.48	GO:0019904	protein domain specific binding
0.47	GO:0042802	identical protein binding
0.46	GO:0008134	transcription factor binding
0.46	GO:0005102	receptor binding
0.42	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.41	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0043021	ribonucleoprotein complex binding

0.83	GO:0005956	protein kinase CK2 complex
0.52	GO:0031519	PcG protein complex
0.40	GO:0005886	plasma membrane
0.37	GO:0016363	nuclear matrix
0.37	GO:0005737	cytoplasm
0.36	GO:0005929	cilium
0.36	GO:0000785	chromatin
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0097708	intracellular vesicle

0.42

GO:0016773

sp|P67881|CYC_CHICK
Cytochrome c
Search

CYCS

0.65	Somatic cytochrome c

0.61	GO:0022900	electron transport chain
0.54	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.45	GO:0006119	oxidative phosphorylation
0.45	GO:0009060	aerobic respiration
0.42	GO:0006915	apoptotic process
0.42	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process
0.42	GO:0042743	hydrogen peroxide metabolic process
0.42	GO:0034465	response to carbon monoxide
0.41	GO:1901857	positive regulation of cellular respiration
0.41	GO:0002931	response to ischemia

0.63	GO:0045155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity
0.63	GO:0020037	heme binding
0.54	GO:0046872	metal ion binding
0.38	GO:0019899	enzyme binding

0.62	GO:0070469	respiratory chain
0.61	GO:0005739	mitochondrion
0.57	GO:0031970	organelle envelope lumen
0.50	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.43	GO:0043209	myelin sheath

sp|P67883|RL30_CHICK
60S ribosomal protein L30
Search

RPL30

0.75	Ribosomal protein L30

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.46	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.44	GO:0050829	defense response to Gram-negative bacterium
0.43	GO:0031640	killing of cells of other organism
0.36	GO:1904571	positive regulation of selenocysteine incorporation
0.35	GO:0097421	liver regeneration
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

0.64	GO:0003735	structural constituent of ribosome
0.39	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.45	GO:0044445	cytosolic part
0.44	GO:0005844	polysome
0.40	GO:0044446	intracellular organelle part
0.39	GO:0005634	nucleus
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|P67885|ANGT_CHICK
Angiotensinogen (Fragment)
Search

0.10	Angiotensinogen (Fragment)

0.30	GO:0035296	regulation of tube diameter
0.30	GO:0050880	regulation of blood vessel size

0.30

GO:0005576

extracellular region

sp|P67962|KC1A_CHICK
Casein kinase I isoform alpha
Search

CSNK1A1

0.75	Casein kinase I alpha S

0.63	GO:0006468	protein phosphorylation
0.48	GO:0018209	peptidyl-serine modification
0.48	GO:0045104	intermediate filament cytoskeleton organization
0.47	GO:1904424	regulation of GTP binding
0.45	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.45	GO:0007030	Golgi organization
0.43	GO:0016055	Wnt signaling pathway
0.42	GO:0006909	phagocytosis
0.42	GO:0048856	anatomical structure development
0.41	GO:0048869	cellular developmental process

0.66	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.34	GO:0042277	peptide binding
0.33	GO:0000287	magnesium ion binding

0.47	GO:0045095	keratin filament
0.47	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex
0.46	GO:0030877	beta-catenin destruction complex
0.46	GO:0016607	nuclear speck
0.46	GO:0036064	ciliary basal body
0.44	GO:0005813	centrosome
0.42	GO:0000777	condensed chromosome kinetochore
0.41	GO:0005829	cytosol
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0000139	Golgi membrane

0.66

GO:0004674

sp|P67964|VEGFA_CHICK
Vascular endothelial growth factor A
Search

VEGFA

0.91	Vascular endothelial growth factor Ab

0.75	GO:0010469	regulation of receptor activity
0.54	GO:0001938	positive regulation of endothelial cell proliferation
0.54	GO:0050927	positive regulation of positive chemotaxis
0.53	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.53	GO:1903570	regulation of protein kinase D signaling
0.53	GO:0045766	positive regulation of angiogenesis
0.52	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation
0.52	GO:0038089	positive regulation of cell migration by vascular endothelial growth factor signaling pathway
0.52	GO:0001525	angiogenesis
0.52	GO:0038091	positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway

0.81	GO:0008201	heparin binding
0.78	GO:0008083	growth factor activity
0.56	GO:0043183	vascular endothelial growth factor receptor 1 binding
0.55	GO:0043184	vascular endothelial growth factor receptor 2 binding
0.51	GO:0001968	fibronectin binding
0.51	GO:0005161	platelet-derived growth factor receptor binding
0.51	GO:0042056	chemoattractant activity
0.48	GO:0005125	cytokine activity
0.39	GO:0038191	neuropilin binding
0.38	GO:0050840	extracellular matrix binding

0.48	GO:0030141	secretory granule
0.47	GO:0005615	extracellular space
0.47	GO:0009986	cell surface
0.36	GO:0005578	proteinaceous extracellular matrix
0.35	GO:0060205	cytoplasmic vesicle lumen
0.35	GO:0044420	extracellular matrix component
0.34	GO:0005634	nucleus
0.33	GO:0005886	plasma membrane

sp|P67966|CSRP1_CHICK
Cysteine and glycine-rich protein 1
Search

CSRP1

0.97	Cysteine and glycine-rich protein 1

0.37	GO:0070527	platelet aggregation
0.36	GO:0031102	neuron projection regeneration
0.36	GO:0060027	convergent extension involved in gastrulation
0.36	GO:0042074	cell migration involved in gastrulation
0.36	GO:0007254	JNK cascade
0.36	GO:0003007	heart morphogenesis
0.35	GO:0016055	Wnt signaling pathway
0.35	GO:0006937	regulation of muscle contraction
0.34	GO:0030036	actin cytoskeleton organization

0.54	GO:0046872	metal ion binding
0.35	GO:0051393	alpha-actinin binding
0.35	GO:0051219	phosphoprotein binding
0.34	GO:0003723	RNA binding

0.54	GO:0097517	contractile actin filament bundle
0.54	GO:0042641	actomyosin
0.53	GO:0005925	focal adhesion
0.52	GO:0031252	cell leading edge
0.44	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.34	GO:0099512	supramolecular fiber
0.33	GO:0043233	organelle lumen
0.33	GO:0043234	protein complex

sp|P67970|INS_CHICK
Insulin
Search

INS

0.95

Insulin

0.76	GO:0010469	regulation of receptor activity
0.70	GO:0006006	glucose metabolic process
0.46	GO:0045818	negative regulation of glycogen catabolic process
0.46	GO:0050995	negative regulation of lipid catabolic process
0.46	GO:0010243	response to organonitrogen compound
0.46	GO:0033861	negative regulation of NAD(P)H oxidase activity
0.46	GO:1902952	positive regulation of dendritic spine maintenance
0.46	GO:2000252	negative regulation of feeding behavior
0.46	GO:0060266	negative regulation of respiratory burst involved in inflammatory response
0.46	GO:0046628	positive regulation of insulin receptor signaling pathway

0.79	GO:0005179	hormone activity
0.49	GO:0005159	insulin-like growth factor receptor binding
0.46	GO:0005158	insulin receptor binding
0.44	GO:0002020	protease binding
0.42	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.38	GO:0030141	secretory granule
0.36	GO:0060205	cytoplasmic vesicle lumen
0.35	GO:0005732	small nucleolar ribonucleoprotein complex
0.35	GO:0031904	endosome lumen
0.35	GO:0005796	Golgi lumen
0.35	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.34	GO:0005829	cytosol
0.34	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0030133	transport vesicle

sp|P68034|ACTC_CHICK
Actin, alpha cardiac muscle 1
Search

ACTC1

0.83	Actin aortic smooth muscle

0.78	GO:0090131	mesenchyme migration
0.63	GO:0010628	positive regulation of gene expression
0.57	GO:0030240	skeletal muscle thin filament assembly
0.56	GO:0033275	actin-myosin filament sliding
0.55	GO:0055003	cardiac myofibril assembly
0.54	GO:0055008	cardiac muscle tissue morphogenesis
0.54	GO:0060047	heart contraction
0.50	GO:0043066	negative regulation of apoptotic process
0.43	GO:0006936	muscle contraction
0.43	GO:0072144	glomerular mesangial cell development

0.53	GO:0017022	myosin binding
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0016887	ATPase activity
0.40	GO:0019901	protein kinase binding
0.34	GO:0005200	structural constituent of cytoskeleton

0.73	GO:0030175	filopodium
0.71	GO:0030027	lamellipodium
0.70	GO:0044297	cell body
0.56	GO:0042643	actomyosin, actin portion
0.54	GO:0044449	contractile fiber part
0.52	GO:0030016	myofibril
0.38	GO:0097517	contractile actin filament bundle
0.38	GO:0070062	extracellular exosome
0.36	GO:0043234	protein complex
0.36	GO:0072562	blood microparticle

0.43

GO:0016887

sp|P68072|GON2_CHICK
Gonadoliberin-2
Search

0.10	Gonadoliberin-2

0.30	GO:0050789	regulation of biological process
0.30	GO:0007275	multicellular organism development
0.30	GO:0065009	regulation of molecular function

0.30	GO:0005488	binding
0.30	GO:0098772	molecular function regulator

0.30

GO:0005576

extracellular region

sp|P68139|ACTS_CHICK
Actin, alpha skeletal muscle
Search

0.84	Actin alpha skeletal muscle

0.69	GO:0090131	mesenchyme migration
0.59	GO:0030240	skeletal muscle thin filament assembly
0.57	GO:0010628	positive regulation of gene expression
0.54	GO:0014706	striated muscle tissue development
0.54	GO:0007517	muscle organ development
0.51	GO:0014904	myotube cell development
0.50	GO:0048747	muscle fiber development
0.49	GO:0033275	actin-myosin filament sliding
0.47	GO:0055006	cardiac cell development
0.46	GO:0060047	heart contraction

0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0017022	myosin binding
0.39	GO:0016887	ATPase activity
0.35	GO:0031013	troponin I binding
0.35	GO:0031432	titin binding
0.35	GO:0048306	calcium-dependent protein binding
0.35	GO:0005523	tropomyosin binding
0.34	GO:0003785	actin monomer binding

0.65	GO:0030175	filopodium
0.64	GO:0030027	lamellipodium
0.62	GO:0044297	cell body
0.56	GO:0042641	actomyosin
0.55	GO:0005884	actin filament
0.54	GO:0030017	sarcomere
0.51	GO:0097517	contractile actin filament bundle
0.50	GO:0036379	myofilament
0.38	GO:0072562	blood microparticle
0.37	GO:0070062	extracellular exosome

0.39

GO:0016887

sp|P68246|TNNI2_CHICK
Troponin I, fast skeletal muscle
Search

TNNI2

0.92	Fast skeletal troponin I

0.53	GO:0003009	skeletal muscle contraction
0.46	GO:0060048	cardiac muscle contraction
0.45	GO:0045893	positive regulation of transcription, DNA-templated
0.43	GO:0090257	regulation of muscle system process
0.42	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.38	GO:0048583	regulation of response to stimulus
0.35	GO:0006887	exocytosis
0.35	GO:0030049	muscle filament sliding
0.32	GO:0007165	signal transduction

0.52	GO:0031014	troponin T binding
0.46	GO:0003779	actin binding
0.34	GO:0046872	metal ion binding
0.32	GO:0004871	signal transducer activity

0.84	GO:0005861	troponin complex
0.41	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P68248|PAHO_CHICK
Pancreatic hormone
Search

PPY

0.81	Pancreatic hormone

0.76	GO:0010469	regulation of receptor activity
0.61	GO:0032098	regulation of appetite
0.59	GO:0007631	feeding behavior
0.57	GO:0007218	neuropeptide signaling pathway
0.54	GO:0007267	cell-cell signaling

0.79	GO:0005179	hormone activity
0.57	GO:0001664	G-protein coupled receptor binding

0.66

GO:0005576

extracellular region

sp|P68259|GLUC_CHICK
Glucagon
Search

GCG

0.97	Preproglucagon B

0.76	GO:0010469	regulation of receptor activity
0.66	GO:0032099	negative regulation of appetite
0.62	GO:0010737	protein kinase A signaling
0.61	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
0.61	GO:1900118	negative regulation of execution phase of apoptosis
0.61	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
0.60	GO:0090280	positive regulation of calcium ion import
0.60	GO:0051571	positive regulation of histone H3-K4 methylation
0.60	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.58	GO:0033138	positive regulation of peptidyl-serine phosphorylation

0.79	GO:0005179	hormone activity
0.53	GO:0042802	identical protein binding
0.50	GO:0031769	glucagon receptor binding
0.37	GO:0017171	serine hydrolase activity
0.36	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.32	GO:0004386	helicase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0003677	DNA binding
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0008144	drug binding

0.66	GO:0005576	extracellular region
0.40	GO:0005737	cytoplasm
0.37	GO:0031983	vesicle lumen
0.35	GO:0097708	intracellular vesicle
0.35	GO:0012505	endomembrane system
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005886	plasma membrane
0.33	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

sp|P68306|THB_CHICK
Thyroid hormone receptor beta
Search

THRB

0.94	Thyroid hormone receptor beta

0.79	GO:0030522	intracellular receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0008050	female courtship behavior
0.54	GO:0060509	Type I pneumocyte differentiation
0.54	GO:0007621	negative regulation of female receptivity
0.50	GO:0008016	regulation of heart contraction

0.85	GO:0004887	thyroid hormone receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.55	GO:0070324	thyroid hormone binding
0.51	GO:0031490	chromatin DNA binding
0.46	GO:0019899	enzyme binding
0.39	GO:0000989	transcription factor activity, transcription factor binding
0.36	GO:0003690	double-stranded DNA binding
0.35	GO:0046983	protein dimerization activity

0.61	GO:0005634	nucleus
0.46	GO:0000785	chromatin
0.44	GO:0043233	organelle lumen
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P68497|MT_CHICK
Metallothionein
Search

0.74	Metallothionein

0.56	GO:0071248	cellular response to metal ion
0.54	GO:0045926	negative regulation of growth
0.52	GO:0010043	response to zinc ion
0.49	GO:0097214	positive regulation of lysosomal membrane permeability
0.49	GO:0010033	response to organic substance
0.48	GO:0055073	cadmium ion homeostasis
0.48	GO:2000376	positive regulation of oxygen metabolic process
0.48	GO:0060547	negative regulation of necrotic cell death
0.48	GO:0055069	zinc ion homeostasis
0.48	GO:0010940	positive regulation of necrotic cell death

0.54	GO:0046872	metal ion binding
0.47	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.45	GO:0030295	protein kinase activator activity
0.38	GO:0008144	drug binding
0.34	GO:0005515	protein binding
0.33	GO:0016209	antioxidant activity

0.53	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0016234	inclusion body
0.45	GO:0008021	synaptic vesicle
0.43	GO:0005634	nucleus
0.39	GO:0097450	astrocyte end-foot
0.38	GO:0043197	dendritic spine
0.38	GO:0014069	postsynaptic density
0.38	GO:0005791	rough endoplasmic reticulum
0.37	GO:0030424	axon
0.37	GO:0005741	mitochondrial outer membrane

sp|P70079|KCRU_CHICK
Creatine kinase U-type, mitochondrial
Search

0.90	Creatine kinase U-typeserine-threonine

0.56	GO:0016310	phosphorylation
0.45	GO:0032091	negative regulation of protein binding
0.43	GO:0043066	negative regulation of apoptotic process
0.36	GO:0006600	creatine metabolic process
0.36	GO:0021549	cerebellum development
0.36	GO:0007519	skeletal muscle tissue development
0.35	GO:0048565	digestive tract development
0.35	GO:0001822	kidney development

0.59	GO:0016301	kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor
0.35	GO:0005515	protein binding

0.45	GO:0043209	myelin sheath
0.44	GO:0005739	mitochondrion
0.38	GO:0019866	organelle inner membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0043204	perikaryon
0.30	GO:0044425	membrane part

0.40

EC:2.7.3

GO:0016775

sp|P70080|TPH1_CHICK
Tryptophan 5-hydroxylase 1
Search

TPH1

0.94	Tryptophan hydroxylase

0.85	GO:0042427	serotonin biosynthetic process
0.68	GO:0009072	aromatic amino acid family metabolic process
0.54	GO:0046849	bone remodeling
0.54	GO:0045600	positive regulation of fat cell differentiation
0.53	GO:0061377	mammary gland lobule development
0.52	GO:0055114	oxidation-reduction process
0.40	GO:0035902	response to immobilization stress
0.39	GO:0007623	circadian rhythm
0.39	GO:0030279	negative regulation of ossification
0.36	GO:0006586	indolalkylamine metabolic process

0.85	GO:0004510	tryptophan 5-monooxygenase activity
0.62	GO:0005506	iron ion binding

0.45	GO:0043005	neuron projection
0.38	GO:0005737	cytoplasm

0.85

EC:1.14.16.4

GO:0004510

sp|P70081|H48_CHICK
Histone H4 type VIII
Search

0.10	Histone H4 type VIII

0.78	GO:0006334	nucleosome assembly
0.69	GO:0006352	DNA-templated transcription, initiation

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.39	GO:0042393	histone binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.34	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P70082|H2AJ_CHICK
Histone H2A.J
Search

HIST2H2AC

0.92	Histone H2A type 2-C

0.52	GO:0006342	chromatin silencing
0.35	GO:0006334	nucleosome assembly
0.33	GO:0006974	cellular response to DNA damage stimulus

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.46	GO:0031974	membrane-enclosed lumen
0.39	GO:0070062	extracellular exosome

sp|P79760|CP1A4_CHICK
Cytochrome P450 1A4
Search

sp|P79761|CP1A5_CHICK
Cytochrome P450 1A5
Search

sp|P79762|ZP3_CHICK
Zona pellucida sperm-binding protein 3
Search

0.92	Zona pellucida glycoprotein C

0.54	GO:0035803	egg coat formation
0.54	GO:2000344	positive regulation of acrosome reaction
0.53	GO:0001809	positive regulation of type IV hypersensitivity
0.53	GO:2000387	regulation of antral ovarian follicle growth
0.53	GO:2000386	positive regulation of ovarian follicle development
0.52	GO:0007339	binding of sperm to zona pellucida
0.52	GO:0033574	response to testosterone
0.52	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process
0.51	GO:0032570	response to progesterone
0.51	GO:0032753	positive regulation of interleukin-4 production

0.47	GO:0032190	acrosin binding
0.46	GO:0048018	receptor ligand activity
0.46	GO:0035804	structural constituent of egg coat
0.41	GO:0030246	carbohydrate binding
0.38	GO:0042802	identical protein binding

0.65	GO:0005576	extracellular region
0.53	GO:0045177	apical part of cell
0.40	GO:0005886	plasma membrane
0.35	GO:0005622	intracellular
0.33	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|P79763|FSHR_CHICK
Follicle-stimulating hormone receptor
Search

FSHR

0.83	Follicle-stimulating hormone receptor

0.85	GO:0042699	follicle-stimulating hormone signaling pathway
0.62	GO:0001545	primary ovarian follicle growth
0.59	GO:0060408	regulation of acetylcholine metabolic process
0.58	GO:0045670	regulation of osteoclast differentiation
0.57	GO:0060011	Sertoli cell proliferation
0.57	GO:0009992	cellular water homeostasis
0.57	GO:0035093	spermatogenesis, exchange of chromosomal proteins
0.57	GO:0045779	negative regulation of bone resorption
0.57	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
0.56	GO:0060009	Sertoli cell development

0.86	GO:0004963	follicle-stimulating hormone receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.44	GO:0001653	peptide receptor activity
0.40	GO:0017046	peptide hormone binding
0.34	GO:0005515	protein binding

0.53	GO:0005886	plasma membrane
0.50	GO:0009986	cell surface
0.38	GO:0005768	endosome
0.30	GO:0016021	integral component of membrane

sp|P79764|GLRX1_CHICK
Glutaredoxin-1
Search

GLRX

0.45	Thioltransferase

0.68	GO:0045454	cell redox homeostasis
0.61	GO:0022900	electron transport chain
0.56	GO:0045838	positive regulation of membrane potential
0.56	GO:2000651	positive regulation of sodium ion transmembrane transporter activity
0.43	GO:0080058	protein deglutathionylation
0.42	GO:0003147	neural crest cell migration involved in heart formation
0.39	GO:0001944	vasculature development
0.39	GO:0007417	central nervous system development
0.37	GO:0010035	response to inorganic substance
0.37	GO:0048878	chemical homeostasis

0.72	GO:0015035	protein disulfide oxidoreductase activity
0.62	GO:0009055	electron transfer activity
0.54	GO:0047485	protein N-terminus binding
0.38	GO:0047139	glutathione-homocystine transhydrogenase activity
0.38	GO:0015038	glutathione disulfide oxidoreductase activity
0.37	GO:0016740	transferase activity
0.35	GO:0019153	protein-disulfide reductase (glutathione) activity
0.32	GO:0003676	nucleic acid binding

0.43	GO:0005634	nucleus
0.43	GO:0005739	mitochondrion
0.38	GO:0005829	cytosol
0.37	GO:0030176	integral component of endoplasmic reticulum membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0031974	membrane-enclosed lumen
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.33	GO:0031967	organelle envelope

0.38

EC:1.8.4.1

GO:0047139

sp|P79765|NDF1_CHICK
Neurogenic differentiation factor 1
Search

NEUROD1

0.90	Neurogenic differentiation factor

0.75	GO:0048699	generation of neurons
0.69	GO:0048468	cell development
0.64	GO:0051960	regulation of nervous system development
0.64	GO:0060284	regulation of cell development
0.59	GO:0021549	cerebellum development
0.59	GO:0003312	pancreatic PP cell differentiation
0.59	GO:0003326	pancreatic A cell fate commitment
0.59	GO:0060730	regulation of intestinal epithelial structure maintenance
0.59	GO:0051091	positive regulation of DNA binding transcription factor activity
0.58	GO:0050807	regulation of synapse organization

0.68	GO:0046983	protein dimerization activity
0.62	GO:0070888	E-box binding
0.58	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.56	GO:0001105	RNA polymerase II transcription coactivator activity
0.56	GO:0001102	RNA polymerase II activating transcription factor binding
0.53	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0003682	chromatin binding
0.45	GO:0003714	transcription corepressor activity
0.34	GO:0008484	sulfuric ester hydrolase activity

0.58	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.43	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm
0.35	GO:0070013	intracellular organelle lumen

0.34

EC:3.1.6

GO:0008484

sp|P79766|NDF4_CHICK
Neurogenic differentiation factor 4
Search

NEUROD4

0.90	Neurogenic differentiation factor

0.77	GO:0048666	neuron development
0.65	GO:0035881	amacrine cell differentiation
0.60	GO:0045597	positive regulation of cell differentiation
0.58	GO:0045165	cell fate commitment
0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0006351	transcription, DNA-templated
0.54	GO:0003312	pancreatic PP cell differentiation
0.54	GO:0060730	regulation of intestinal epithelial structure maintenance
0.54	GO:0010468	regulation of gene expression

0.68	GO:0046983	protein dimerization activity
0.53	GO:0070888	E-box binding
0.52	GO:0001105	RNA polymerase II transcription coactivator activity
0.52	GO:0001102	RNA polymerase II activating transcription factor binding
0.50	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0003682	chromatin binding

0.57	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.41	GO:0044446	intracellular organelle part
0.37	GO:0005737	cytoplasm
0.34	GO:0070013	intracellular organelle lumen

sp|P79769|TSN_CHICK
Translin
Search

TSN

0.50

Translin

0.55	GO:0016070	RNA metabolic process
0.37	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.35	GO:0016246	RNA interference
0.35	GO:0071359	cellular response to dsRNA
0.33	GO:0006310	DNA recombination
0.32	GO:0010467	gene expression

0.74	GO:0003697	single-stranded DNA binding
0.65	GO:0043565	sequence-specific DNA binding
0.59	GO:0003723	RNA binding
0.50	GO:0042802	identical protein binding
0.39	GO:0032403	protein complex binding
0.37	GO:0004519	endonuclease activity

0.44	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P79772|FOXD3_CHICK
Forkhead box protein D3
Search

0.91	Winged helix protein CWH-1

0.57	GO:0006355	regulation of transcription, DNA-templated
0.51	GO:0009653	anatomical structure morphogenesis
0.51	GO:0030154	cell differentiation
0.50	GO:1903507	negative regulation of nucleic acid-templated transcription
0.49	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.49	GO:0048892	lateral line nerve development
0.49	GO:0060485	mesenchyme development
0.48	GO:1903508	positive regulation of nucleic acid-templated transcription
0.48	GO:0097066	response to thyroid hormone
0.48	GO:0010629	negative regulation of gene expression

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding
0.38	GO:0008301	DNA binding, bending
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.42	GO:0000785	chromatin
0.41	GO:0070013	intracellular organelle lumen
0.34	GO:0005667	transcription factor complex

sp|P79774|SNAT_CHICK
Serotonin N-acetyltransferase
Search

AANAT

0.94	Retinal arylalkylamine N-acetyltransferase

0.57	GO:0030187	melatonin biosynthetic process
0.53	GO:0071320	cellular response to cAMP
0.53	GO:0007623	circadian rhythm
0.50	GO:0006474	N-terminal protein amino acid acetylation
0.43	GO:0009416	response to light stimulus
0.39	GO:0051412	response to corticosterone
0.39	GO:0034695	response to prostaglandin E
0.38	GO:0010043	response to zinc ion
0.38	GO:0051592	response to calcium ion
0.38	GO:0032868	response to insulin

0.67	GO:0008080	N-acetyltransferase activity
0.39	GO:0071889	14-3-3 protein binding

0.50	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0005829	cytosol

0.67

GO:0008080

sp|P79775|ANF1_CHICK
Homeobox protein ANF-1
Search

HESX1

0.97	Homeobox expressed in ES cells 1-B

0.57	GO:0021983	pituitary gland development
0.57	GO:0030916	otic vesicle formation
0.57	GO:0043584	nose development
0.57	GO:0048853	forebrain morphogenesis
0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.49	GO:1902679	negative regulation of RNA biosynthetic process
0.37	GO:0060061	Spemann organizer formation
0.35	GO:0045664	regulation of neuron differentiation

0.61	GO:0043565	sequence-specific DNA binding
0.55	GO:0047485	protein N-terminus binding
0.54	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0008022	protein C-terminus binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003682	chromatin binding
0.50	GO:0003690	double-stranded DNA binding
0.34	GO:0008134	transcription factor binding
0.32	GO:0003746	translation elongation factor activity

0.61

GO:0005634

nucleus

sp|P79777|BRAC_CHICK
Brachyury protein
Search

0.97	T-box transcription factor Brachyury

0.60	GO:0014028	notochord formation
0.60	GO:0003257	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
0.59	GO:0036342	post-anal tail morphogenesis
0.58	GO:0006351	transcription, DNA-templated
0.58	GO:0007341	penetration of zona pellucida
0.58	GO:0007509	mesoderm migration involved in gastrulation
0.57	GO:0001839	neural plate morphogenesis
0.57	GO:0001756	somitogenesis
0.57	GO:0061371	determination of heart left/right asymmetry
0.57	GO:0023019	signal transduction involved in regulation of gene expression

0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0001158	enhancer sequence-specific DNA binding
0.57	GO:0001102	RNA polymerase II activating transcription factor binding
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.36	GO:0051087	chaperone binding

0.61	GO:0005634	nucleus
0.50	GO:0000785	chromatin
0.47	GO:0070013	intracellular organelle lumen
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P79778|TBXT_CHICK
T-box-containing protein TBXT
Search

0.64	T brachyury transcription factor

0.73	GO:0003257	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
0.71	GO:0007341	penetration of zona pellucida
0.71	GO:0014028	notochord formation
0.71	GO:0007509	mesoderm migration involved in gastrulation
0.71	GO:0001839	neural plate morphogenesis
0.70	GO:0023019	signal transduction involved in regulation of gene expression
0.69	GO:0036342	post-anal tail morphogenesis
0.68	GO:0060395	SMAD protein signal transduction
0.67	GO:0001570	vasculogenesis
0.67	GO:0001756	somitogenesis

0.68	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.68	GO:0001102	RNA polymerase II activating transcription factor binding
0.67	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.67	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.64	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.39	GO:0051087	chaperone binding

0.61	GO:0005634	nucleus
0.59	GO:0000785	chromatin
0.55	GO:0043233	organelle lumen
0.43	GO:0005737	cytoplasm

sp|P79779|TBX6L_CHICK
T-box-containing protein TBX6L (Fragment)
Search

0.88	T-box protein VegT-A

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0072001	renal system development
0.49	GO:0007507	heart development
0.49	GO:0035295	tube development
0.48	GO:0009888	tissue development
0.47	GO:0009790	embryo development
0.46	GO:0030154	cell differentiation

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.46	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding

0.61	GO:0005634	nucleus
0.37	GO:0034708	methyltransferase complex
0.36	GO:0043233	organelle lumen
0.35	GO:0017053	transcriptional repressor complex
0.34	GO:0044446	intracellular organelle part
0.34	GO:0005667	transcription factor complex
0.30	GO:0031224	intrinsic component of membrane

sp|P79780|SIAL_CHICK
Bone sialoprotein 2
Search

IBSP

0.97	Bone sialoprotein II

0.75	GO:0001503	ossification
0.66	GO:0007155	cell adhesion
0.57	GO:0031214	biomineral tissue development
0.53	GO:0030198	extracellular matrix organization
0.53	GO:0071363	cellular response to growth factor stimulus
0.50	GO:0045785	positive regulation of cell adhesion
0.37	GO:0006364	rRNA processing
0.37	GO:0007229	integrin-mediated signaling pathway
0.36	GO:0030154	cell differentiation
0.35	GO:0048523	negative regulation of cellular process

0.54	GO:0005178	integrin binding
0.35	GO:0051082	unfolded protein binding
0.35	GO:0003676	nucleic acid binding
0.34	GO:0043021	ribonucleoprotein complex binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0005523	tropomyosin binding
0.34	GO:0044547	DNA topoisomerase binding
0.33	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.33	GO:0008022	protein C-terminus binding
0.33	GO:0097367	carbohydrate derivative binding

0.61	GO:0005576	extracellular region
0.43	GO:0031982	vesicle
0.38	GO:0005730	nucleolus
0.38	GO:0030684	preribosome
0.37	GO:0005732	small nucleolar ribonucleoprotein complex
0.36	GO:0005654	nucleoplasm
0.36	GO:0019013	viral nucleocapsid
0.35	GO:0043234	protein complex
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0005680	anaphase-promoting complex

0.33

GO:0016773

sp|P79781|RS27A_CHICK
Ubiquitin-40S ribosomal protein S27a
Search

RPS27A

0.66	Epididymis luminal protein 112

0.60	GO:0006518	peptide metabolic process
0.59	GO:0043604	amide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:1901566	organonitrogen compound biosynthetic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.36	GO:0006301	postreplication repair
0.35	GO:0035635	entry of bacterium into host cell
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0035666	TRIF-dependent toll-like receptor signaling pathway

0.63	GO:0003735	structural constituent of ribosome
0.36	GO:0046872	metal ion binding
0.33	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.51	GO:0043209	myelin sheath
0.47	GO:0044445	cytosolic part
0.41	GO:0044446	intracellular organelle part
0.36	GO:0005634	nucleus
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0070062	extracellular exosome
0.34	GO:0030139	endocytic vesicle
0.34	GO:0012506	vesicle membrane
0.34	GO:0005768	endosome

sp|P79782|TCF15_CHICK
Transcription factor 15
Search

TCF15

0.97	Scleraxis bHLH transcription factor

0.55	GO:0061053	somite development
0.55	GO:0007498	mesoderm development
0.55	GO:0003016	respiratory system process
0.55	GO:0060231	mesenchymal to epithelial transition
0.54	GO:0045198	establishment of epithelial cell apical/basal polarity
0.54	GO:0050884	neuromuscular process controlling posture
0.54	GO:0042755	eating behavior
0.54	GO:0060485	mesenchyme development
0.54	GO:0048705	skeletal system morphogenesis
0.54	GO:0036342	post-anal tail morphogenesis

0.68	GO:0046983	protein dimerization activity
0.53	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.51	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.43	GO:0043425	bHLH transcription factor binding
0.41	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.41	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

0.51	GO:0005667	transcription factor complex
0.45	GO:0005634	nucleus
0.41	GO:0044446	intracellular organelle part

tr|P79783|P79783_CHICK
CMP-NeuAc:GM3 sialyltransferase
Search

ST8SIA1

0.97	Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase

0.83	GO:0097503	sialylation
0.74	GO:0006486	protein glycosylation
0.53	GO:0034605	cellular response to heat
0.52	GO:0008284	positive regulation of cell proliferation
0.42	GO:0006665	sphingolipid metabolic process
0.38	GO:0009247	glycolipid biosynthetic process
0.36	GO:0009311	oligosaccharide metabolic process
0.35	GO:0043604	amide biosynthetic process
0.35	GO:0016051	carbohydrate biosynthetic process
0.35	GO:0007275	multicellular organism development

0.83	GO:0008373	sialyltransferase activity
0.32	GO:0008146	sulfotransferase activity

0.68	GO:0005794	Golgi apparatus
0.38	GO:0098588	bounding membrane of organelle
0.38	GO:0031984	organelle subcompartment
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:2.4.99

GO:0008373

sp|P79784|ENTP2_CHICK
Ectonucleoside triphosphate diphosphohydrolase 2
Search

ENTPD2

0.96	Ectonucleoside triphosphate diphosphohydrolase 2 b

0.55	GO:0009137	purine nucleoside diphosphate catabolic process
0.55	GO:0009191	ribonucleoside diphosphate catabolic process
0.52	GO:0030168	platelet activation
0.46	GO:0007186	G-protein coupled receptor signaling pathway
0.46	GO:0009179	purine ribonucleoside diphosphate metabolic process
0.38	GO:0045471	response to ethanol
0.38	GO:0046688	response to copper ion
0.37	GO:0034656	nucleobase-containing small molecule catabolic process
0.37	GO:0035457	cellular response to interferon-alpha
0.36	GO:0010996	response to auditory stimulus

0.51	GO:0017110	nucleoside-diphosphatase activity
0.42	GO:0017111	nucleoside-triphosphatase activity
0.38	GO:0102489	GTP phosphohydrolase activity
0.38	GO:0102490	8-oxo-dGTP phosphohydrolase activity
0.38	GO:0102491	dGTP phosphohydrolase activity
0.38	GO:0102488	dTTP phosphohydrolase activity
0.38	GO:0102485	dATP phosphohydrolase activity
0.38	GO:0102486	dCTP phosphohydrolase activity
0.38	GO:0102487	dUTP phosphohydrolase activity
0.35	GO:0032559	adenyl ribonucleotide binding

0.53	GO:0005605	basal lamina
0.40	GO:0005886	plasma membrane
0.38	GO:0070062	extracellular exosome
0.36	GO:0044297	cell body
0.35	GO:0009986	cell surface
0.35	GO:0120025	plasma membrane bounded cell projection
0.34	GO:0012505	endomembrane system
0.34	GO:0014069	postsynaptic density
0.34	GO:0036477	somatodendritic compartment
0.34	GO:0099503	secretory vesicle

0.51

EC:3.6.1.6

GO:0017110

sp|P79785|AGTR1_CHICK
Type-1 angiotensin II receptor
Search

AGTR1

0.97	Type-1 angiotensin II receptor

0.85	GO:0038166	angiotensin-activated signaling pathway
0.82	GO:0019229	regulation of vasoconstriction
0.41	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.41	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.40	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin
0.40	GO:0042756	drinking behavior
0.40	GO:0003071	renal system process involved in regulation of systemic arterial blood pressure
0.40	GO:0071549	cellular response to dexamethasone stimulus
0.40	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
0.40	GO:0045777	positive regulation of blood pressure

0.85	GO:0004945	angiotensin type II receptor activity
0.43	GO:0001596	angiotensin type I receptor activity
0.40	GO:0031711	bradykinin receptor binding
0.39	GO:0017046	peptide hormone binding
0.39	GO:0043621	protein self-association
0.37	GO:0031748	D1 dopamine receptor binding
0.37	GO:0001965	G-protein alpha-subunit binding
0.36	GO:0046982	protein heterodimerization activity
0.36	GO:0019901	protein kinase binding
0.33	GO:0004950	chemokine receptor activity

0.39	GO:0031983	vesicle lumen
0.39	GO:0005886	plasma membrane
0.37	GO:0012506	vesicle membrane
0.36	GO:0055037	recycling endosome
0.36	GO:0030425	dendrite
0.36	GO:0031968	organelle outer membrane
0.35	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

sp|P79795|NRP1_CHICK
Neuropilin-1
Search

NRP1

0.90	Neuropilin

0.86	GO:0035767	endothelial cell chemotaxis
0.85	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.85	GO:0038084	vascular endothelial growth factor signaling pathway
0.83	GO:0071526	semaphorin-plexin signaling pathway
0.82	GO:0001525	angiogenesis
0.81	GO:0007411	axon guidance
0.77	GO:0009887	animal organ morphogenesis
0.59	GO:0038189	neuropilin signaling pathway
0.59	GO:0006930	substrate-dependent cell migration, cell extension
0.58	GO:1905040	otic placode development

0.85	GO:0005021	vascular endothelial growth factor-activated receptor activity
0.84	GO:0017154	semaphorin receptor activity
0.82	GO:0019838	growth factor binding
0.53	GO:0046872	metal ion binding
0.51	GO:0005096	GTPase activator activity
0.51	GO:0019901	protein kinase binding
0.40	GO:0008201	heparin binding
0.35	GO:0015026	coreceptor activity
0.35	GO:0019955	cytokine binding

0.56	GO:0097443	sorting endosome
0.55	GO:0005883	neurofilament
0.54	GO:0005925	focal adhesion
0.52	GO:0030424	axon
0.52	GO:0005769	early endosome
0.48	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.40	GO:0030426	growth cone
0.37	GO:0070852	cell body fiber
0.37	GO:0043025	neuronal cell body

sp|P79880|GUC1A_CHICK
Guanylyl cyclase-activating protein 1
Search

GUCA1A

0.96	Guanylate cyclase activating protein 1

0.82	GO:0031284	positive regulation of guanylate cyclase activity
0.70	GO:0007601	visual perception
0.52	GO:0007602	phototransduction
0.40	GO:0071277	cellular response to calcium ion
0.35	GO:0022400	regulation of rhodopsin mediated signaling pathway

0.84	GO:0008048	calcium sensitive guanylate cyclase activator activity
0.70	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding
0.33	GO:0008270	zinc ion binding

0.72	GO:0001750	photoreceptor outer segment
0.39	GO:0001917	photoreceptor inner segment
0.35	GO:0060170	ciliary membrane

sp|P79881|GUC1B_CHICK
Guanylyl cyclase-activating protein 2
Search

GUCA1B

0.96	Guanylyl cyclase-activating protein 2

0.58	GO:0031284	positive regulation of guanylate cyclase activity
0.53	GO:0007601	visual perception
0.44	GO:0007602	phototransduction
0.37	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.37	GO:0007168	receptor guanylyl cyclase signaling pathway
0.36	GO:0007589	body fluid secretion
0.35	GO:0007267	cell-cell signaling

0.69	GO:0005509	calcium ion binding
0.59	GO:0008048	calcium sensitive guanylate cyclase activator activity

0.40	GO:0001750	photoreceptor outer segment
0.39	GO:0001917	photoreceptor inner segment
0.36	GO:0060170	ciliary membrane

sp|P79987|HIRA_CHICK
Protein HIRA
Search

sp|P79995|CAD10_CHICK
Cadherin-10
Search

CDH10

0.96	Transmembrane glycoprotein cadherin-10

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.49	GO:0007219	Notch signaling pathway
0.36	GO:0034332	adherens junction organization

0.70

GO:0005509

calcium ion binding

0.56	GO:0005886	plasma membrane
0.34	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part

sp|P79996|MK09_CHICK
Mitogen-activated protein kinase 9
Search

MAPK9

0.59	Mitogen-activated protein kinase

0.79	GO:0000165	MAPK cascade
0.58	GO:0071276	cellular response to cadmium ion
0.57	GO:0061833	protein localization to tricellular tight junction
0.56	GO:0031098	stress-activated protein kinase signaling cascade
0.56	GO:0010744	positive regulation of macrophage derived foam cell differentiation
0.55	GO:0071803	positive regulation of podosome assembly
0.55	GO:0018105	peptidyl-serine phosphorylation
0.53	GO:2001235	positive regulation of apoptotic signaling pathway
0.52	GO:0042752	regulation of circadian rhythm
0.52	GO:0034614	cellular response to reactive oxygen species

0.81	GO:0004707	MAP kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.49	GO:0008134	transcription factor binding
0.45	GO:0035033	histone deacetylase regulator activity
0.42	GO:0042826	histone deacetylase binding
0.35	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.35	GO:0031435	mitogen-activated protein kinase kinase kinase binding

0.46	GO:0005829	cytosol
0.45	GO:0043005	neuron projection
0.43	GO:0005739	mitochondrion
0.41	GO:0005634	nucleus
0.35	GO:0043204	perikaryon
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part

0.81	EC:2.7.11.24	GO:0004707
0.81	KEGG:R00162	GO:0004707

sp|P80026|PRVM_CHICK
Parvalbumin, muscle
Search

PVALB

0.86	Parvalbumin alpha

0.39	GO:0051480	regulation of cytosolic calcium ion concentration
0.33	GO:0045893	positive regulation of transcription, DNA-templated

0.70	GO:0005509	calcium ion binding
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0046982	protein heterodimerization activity
0.34	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0043565	sequence-specific DNA binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0030424	axon
0.39	GO:0043679	axon terminus
0.39	GO:0043025	neuronal cell body
0.38	GO:0005737	cytoplasm
0.36	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.35	GO:0043234	protein complex
0.33	GO:0031514	motile cilium

sp|P80226|FABPL_CHICK
Fatty acid-binding protein, liver
Search

0.81	Liver-basic fatty acid binding protein a

0.36	GO:0006869	lipid transport
0.35	GO:0043484	regulation of RNA splicing
0.33	GO:0051603	proteolysis involved in cellular protein catabolic process

0.72	GO:0008289	lipid binding
0.49	GO:0032052	bile acid binding
0.35	GO:0043178	alcohol binding
0.34	GO:0070003	threonine-type peptidase activity
0.33	GO:0019842	vitamin binding
0.33	GO:0004175	endopeptidase activity
0.32	GO:0003676	nucleic acid binding

0.36	GO:0005737	cytoplasm
0.34	GO:0005839	proteasome core complex
0.30	GO:0016020	membrane

sp|P80389|AMP1_CHICK
Antimicrobial peptide CHP1
Search

0.92	Antimicrobial peptide CHP1

0.72	GO:0006952	defense response
0.60	GO:0009617	response to bacterium
0.56	GO:0009620	response to fungus
0.54	GO:0031640	killing of cells of other organism

0.66	GO:0005576	extracellular region
0.52	GO:0030141	secretory granule

sp|P80565|FABPM_CHICK
Fatty acid-binding protein, smooth muscle (Fragments)
Search

0.62	Fatty acid binding protein 3

0.41	GO:0048513	animal organ development
0.39	GO:2001245	regulation of phosphatidylcholine biosynthetic process
0.39	GO:0055091	phospholipid homeostasis
0.39	GO:0044539	long-chain fatty acid import
0.39	GO:0050727	regulation of inflammatory response
0.39	GO:0046320	regulation of fatty acid oxidation
0.38	GO:0042632	cholesterol homeostasis
0.38	GO:0007368	determination of left/right symmetry
0.37	GO:0060562	epithelial tube morphogenesis
0.37	GO:0043009	chordate embryonic development

0.72	GO:0008289	lipid binding
0.40	GO:0033293	monocarboxylic acid binding
0.36	GO:0008092	cytoskeletal protein binding

0.37	GO:0005615	extracellular space
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P80566|SODC_CHICK
Superoxide dismutase [Cu-Zn]
Search

SOD1

0.51	Cu/Zn-superoxide dismutase

0.75	GO:0071450	cellular response to oxygen radical
0.75	GO:0000303	response to superoxide
0.75	GO:0006801	superoxide metabolic process
0.69	GO:0098869	cellular oxidant detoxification
0.54	GO:0045541	negative regulation of cholesterol biosynthetic process
0.53	GO:0060087	relaxation of vascular smooth muscle
0.53	GO:0050665	hydrogen peroxide biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0060088	auditory receptor cell stereocilium organization
0.52	GO:0032287	peripheral nervous system myelin maintenance

0.77	GO:0004784	superoxide dismutase activity
0.54	GO:0030346	protein phosphatase 2B binding
0.54	GO:0046872	metal ion binding
0.50	GO:0048365	Rac GTPase binding
0.48	GO:0051087	chaperone binding
0.46	GO:0042802	identical protein binding
0.35	GO:0046983	protein dimerization activity
0.33	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0004601	peroxidase activity
0.32	GO:0003723	RNA binding

0.52	GO:0032839	dendrite cytoplasm
0.50	GO:0043025	neuronal cell body
0.49	GO:1904115	axon cytoplasm
0.48	GO:0005615	extracellular space
0.48	GO:0043209	myelin sheath
0.47	GO:0031012	extracellular matrix
0.47	GO:0005777	peroxisome
0.46	GO:0031410	cytoplasmic vesicle
0.46	GO:0005829	cytosol
0.45	GO:0005634	nucleus

0.77	EC:1.15.1.1	GO:0004784
0.33	KEGG:R03876	GO:0004842

sp|P80585|TBCA_CHICK
Tubulin-specific chaperone A
Search

TBCA

0.73	Tubulin-specific chaperone A

0.84	GO:0007021	tubulin complex assembly
0.84	GO:0007023	post-chaperonin tubulin folding pathway
0.38	GO:0007420	brain development

0.84	GO:0048487	beta-tubulin binding
0.34	GO:0051087	chaperone binding
0.33	GO:0003723	RNA binding

0.73	GO:0005874	microtubule
0.49	GO:0005737	cytoplasm
0.45	GO:0005730	nucleolus
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P80896|RPN1_CHICK
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Fragments)
Search

RPN1

0.62	Ribophorin I

0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.60	GO:0006464	cellular protein modification process

0.84

GO:0004579

dolichyl-diphosphooligosaccharide-protein glycotransferase activity

0.70	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:2.4.1.119

GO:0004579

sp|P80897|RPN2_CHICK
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (Fragments)
Search

RPN2

0.58	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (Fragments)

0.80

GO:0006487

protein N-linked glycosylation

0.45

GO:0016740

transferase activity

0.82	GO:0008250	oligosaccharyltransferase complex
0.30	GO:0031224	intrinsic component of membrane

0.45

EC:2

GO:0016740

sp|P81021|VIGLN_CHICK
Vigilin
Search

HDLBP

0.93	High density lipoprotein binding protein (Vigilin)

0.43	GO:0071391	cellular response to estrogen stimulus
0.39	GO:0008203	cholesterol metabolic process
0.37	GO:0006869	lipid transport
0.35	GO:0034384	high-density lipoprotein particle clearance

0.59	GO:0003723	RNA binding
0.38	GO:0045296	cadherin binding
0.34	GO:0008289	lipid binding

0.48	GO:0005829	cytosol
0.39	GO:0034364	high-density lipoprotein particle
0.35	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane

sp|P81073|AMPD1_CHICK
AMP deaminase 1 (Fragment)
Search

AMPD1

0.71	AMP deaminase 1 (Fragment)

0.78	GO:0032264	IMP salvage
0.36	GO:0010033	response to organic substance
0.33	GO:0007165	signal transduction

0.82	GO:0003876	AMP deaminase activity
0.49	GO:0046872	metal ion binding
0.39	GO:0032036	myosin heavy chain binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.82

EC:3.5.4.6

GO:0003876

sp|P81475|CFBL_CHICK
Complement factor B-like protease (Fragment)
Search

0.11	Complement factor B-like protease (Fragment)

0.81	GO:0006956	complement activation
0.79	GO:0002455	humoral immune response mediated by circulating immunoglobulin
0.60	GO:0006508	proteolysis
0.47	GO:0045087	innate immune response
0.47	GO:2000427	positive regulation of apoptotic cell clearance
0.44	GO:0009617	response to bacterium
0.40	GO:0007584	response to nutrient
0.38	GO:0030449	regulation of complement activation
0.36	GO:0006898	receptor-mediated endocytosis

0.69	GO:0004252	serine-type endopeptidase activity
0.37	GO:0046872	metal ion binding
0.37	GO:0005044	scavenger receptor activity
0.35	GO:0005515	protein binding

0.62	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P81476|RNL2_CHICK
Ribonuclease CL2
Search

0.40	Ribonuclease pancreatic

0.59	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.42	GO:0001525	angiogenesis
0.41	GO:0042742	defense response to bacterium
0.41	GO:0019730	antimicrobial humoral response
0.40	GO:0008284	positive regulation of cell proliferation
0.38	GO:0016070	RNA metabolic process
0.38	GO:0034655	nucleobase-containing compound catabolic process
0.38	GO:0044265	cellular macromolecule catabolic process
0.38	GO:0071222	cellular response to lipopolysaccharide
0.37	GO:0045087	innate immune response

0.61	GO:0004519	endonuclease activity
0.51	GO:0003676	nucleic acid binding
0.43	GO:0004540	ribonuclease activity

0.44	GO:0005576	extracellular region
0.40	GO:0030141	secretory granule
0.36	GO:0005730	nucleolus
0.30	GO:0016020	membrane

sp|P81628|ERP29_CHICK
Endoplasmic reticulum resident protein 29 (Fragment)
Search

ERP29

0.97	Endoplasmic reticulum resident protein 29

0.70	GO:0009306	protein secretion
0.66	GO:0000187	activation of MAPK activity
0.66	GO:0050709	negative regulation of protein secretion
0.61	GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.58	GO:0010628	positive regulation of gene expression
0.55	GO:0010629	negative regulation of gene expression
0.48	GO:0006886	intracellular protein transport
0.48	GO:0006457	protein folding
0.36	GO:0043335	protein unfolding
0.36	GO:0034976	response to endoplasmic reticulum stress

0.41	GO:0051087	chaperone binding
0.41	GO:0042803	protein homodimerization activity
0.37	GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds
0.34	GO:0016887	ATPase activity
0.34	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.84	GO:0005788	endoplasmic reticulum lumen
0.68	GO:0042470	melanosome
0.61	GO:0009986	cell surface
0.44	GO:0005790	smooth endoplasmic reticulum
0.41	GO:0030133	transport vesicle
0.39	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.37

EC:5.3.4

GO:0016864

sp|P83038|HDAC4_CHICK
Histone deacetylase 4
Search

HDAC4

0.51	Histone deacetylase

0.80	GO:0016575	histone deacetylation
0.54	GO:0034983	peptidyl-lysine deacetylation
0.54	GO:0014894	response to denervation involved in regulation of muscle adaptation
0.54	GO:0006351	transcription, DNA-templated
0.54	GO:0010832	negative regulation of myotube differentiation
0.54	GO:0033235	positive regulation of protein sumoylation
0.54	GO:0045820	negative regulation of glycolytic process
0.54	GO:0001501	skeletal system development
0.54	GO:0048742	regulation of skeletal muscle fiber development
0.54	GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II

0.81	GO:0004407	histone deacetylase activity
0.73	GO:0034979	NAD-dependent protein deacetylase activity
0.53	GO:0046872	metal ion binding
0.52	GO:0070491	repressing transcription factor binding
0.52	GO:0033613	activating transcription factor binding
0.52	GO:0042826	histone deacetylase binding
0.51	GO:0001085	RNA polymerase II transcription factor binding
0.51	GO:0001047	core promoter binding
0.50	GO:0003714	transcription corepressor activity
0.49	GO:0019901	protein kinase binding

0.81	GO:0000118	histone deacetylase complex
0.52	GO:0042641	actomyosin
0.51	GO:0031594	neuromuscular junction
0.50	GO:0017053	transcriptional repressor complex
0.45	GO:0005829	cytosol
0.39	GO:0031672	A band
0.38	GO:0030018	Z disc
0.35	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0004407

sp|P83145|UK114_CHICK
Ribonuclease UK114 (Fragments)
Search

sp|P84023|SMAD3_CHICK
Mothers against decapentaplegic homolog 3
Search

SMAD3

0.65	Mothers against decapentaplegic homolog

0.83	GO:0007179	transforming growth factor beta receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0006355	regulation of transcription, DNA-templated
0.55	GO:0033689	negative regulation of osteoblast proliferation
0.55	GO:0048617	embryonic foregut morphogenesis
0.55	GO:0007183	SMAD protein complex assembly
0.55	GO:0048340	paraxial mesoderm morphogenesis
0.55	GO:0051481	negative regulation of cytosolic calcium ion concentration
0.55	GO:0002076	osteoblast development
0.54	GO:0038092	nodal signaling pathway

0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0031962	mineralocorticoid receptor binding
0.56	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
0.55	GO:0035259	glucocorticoid receptor binding
0.54	GO:0003677	DNA binding
0.54	GO:0017151	DEAD/H-box RNA helicase binding
0.54	GO:0070410	co-SMAD binding
0.54	GO:0070878	primary miRNA binding
0.54	GO:0070412	R-SMAD binding
0.53	GO:0043425	bHLH transcription factor binding

0.74	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.55	GO:0071141	SMAD protein complex
0.49	GO:0043235	receptor complex
0.49	GO:0005737	cytoplasm
0.47	GO:0000785	chromatin
0.45	GO:0070013	intracellular organelle lumen
0.45	GO:0012505	endomembrane system
0.43	GO:0019866	organelle inner membrane
0.41	GO:0005886	plasma membrane

sp|P84169|PSD13_CHICK
26S proteasome non-ATPase regulatory subunit 13
Search

PSMD13

0.90	26S proteasome non-ATPase regulatory subunit 13

0.54	GO:0007127	meiosis I
0.49	GO:0043248	proteasome assembly
0.46	GO:0006511	ubiquitin-dependent protein catabolic process
0.46	GO:0030097	hemopoiesis
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.36	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.36	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.36	GO:0038095	Fc-epsilon receptor signaling pathway
0.36	GO:1902036	regulation of hematopoietic stem cell differentiation

0.42	GO:0005198	structural molecule activity
0.33	GO:0004175	endopeptidase activity

0.69	GO:1905369	endopeptidase complex
0.57	GO:0043234	protein complex
0.44	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.37	GO:0070062	extracellular exosome
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0034774	secretory granule lumen
0.30	GO:0016020	membrane

sp|P84172|EFTU_CHICK
Elongation factor Tu, mitochondrial (Fragment)
Search

TUFM

0.44	Tu translation elongation factor, mitochondrial

0.68	GO:0006414	translational elongation
0.39	GO:0032543	mitochondrial translation
0.38	GO:0045471	response to ethanol
0.34	GO:0046686	response to cadmium ion
0.33	GO:0006886	intracellular protein transport
0.33	GO:0061025	membrane fusion
0.33	GO:0016192	vesicle-mediated transport

0.68	GO:0003746	translation elongation factor activity
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005484	SNAP receptor activity
0.34	GO:0050897	cobalt ion binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0030554	adenyl nucleotide binding

0.52	GO:0042645	mitochondrial nucleoid
0.51	GO:0043209	myelin sheath
0.43	GO:0031966	mitochondrial membrane
0.43	GO:0019866	organelle inner membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005618	cell wall

sp|P84173|PHB_CHICK
Prohibitin
Search

PHB

0.84	Prohibitin transcript variant 2

0.55	GO:0045917	positive regulation of complement activation
0.54	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway
0.54	GO:0050847	progesterone receptor signaling pathway
0.54	GO:0010944	negative regulation of transcription by competitive promoter binding
0.54	GO:0060766	negative regulation of androgen receptor signaling pathway
0.53	GO:0071354	cellular response to interleukin-6
0.53	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
0.52	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.51	GO:0042177	negative regulation of protein catabolic process
0.51	GO:0030308	negative regulation of cell growth

0.56	GO:0001850	complement component C3a binding
0.55	GO:0001851	complement component C3b binding
0.55	GO:0031871	proteinase activated receptor binding
0.51	GO:0042826	histone deacetylase binding
0.51	GO:0008022	protein C-terminus binding
0.48	GO:0044212	transcription regulatory region DNA binding
0.46	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding

0.50	GO:0043209	myelin sheath
0.50	GO:0005769	early endosome
0.49	GO:0009986	cell surface
0.46	GO:0005654	nucleoplasm
0.44	GO:0005887	integral component of plasma membrane
0.44	GO:0031966	mitochondrial membrane
0.44	GO:0019866	organelle inner membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:0031312	extrinsic component of organelle membrane
0.35	GO:0031968	organelle outer membrane

sp|P84175|RS12_CHICK
40S ribosomal protein S12
Search

RPS12

0.67	40S ribosomal protein S12

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0010243	response to organonitrogen compound
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis

0.64	GO:0003735	structural constituent of ribosome
0.33	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.48	GO:0044445	cytosolic part
0.43	GO:0005794	Golgi apparatus
0.42	GO:0044446	intracellular organelle part
0.33	GO:0043233	organelle lumen
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P84229|H32_CHICK
Histone H3.2
Search

0.43	GO:0006334	nucleosome assembly
0.35	GO:0006352	DNA-templated transcription, initiation

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.39	GO:0031491	nucleosome binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.36	GO:0005700	polytene chromosome
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P84247|H33_CHICK
Histone H3.3
Search

0.43	GO:0006334	nucleosome assembly
0.37	GO:0007140	male meiotic nuclear division
0.36	GO:0034724	DNA replication-independent nucleosome organization
0.36	GO:0030307	positive regulation of cell growth

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.45	GO:0031491	nucleosome binding
0.39	GO:0098770	FBXO family protein binding
0.35	GO:0001067	regulatory region nucleic acid binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.37	GO:0005700	polytene chromosome
0.35	GO:0000781	chromosome, telomeric region
0.34	GO:0043233	organelle lumen
0.33	GO:0043234	protein complex

sp|P84407|FETA_CHICK
Alpha-fetoprotein
Search

ALB

0.86	Serum albumin

0.50	GO:0001542	ovulation from ovarian follicle
0.50	GO:0042448	progesterone metabolic process
0.49	GO:0051659	maintenance of mitochondrion location
0.48	GO:0060395	SMAD protein signal transduction
0.47	GO:0019836	hemolysis by symbiont of host erythrocytes
0.44	GO:0009267	cellular response to starvation
0.44	GO:0043066	negative regulation of apoptotic process
0.39	GO:0071693	protein transport within extracellular region
0.37	GO:0050821	protein stabilization
0.36	GO:0051180	vitamin transport

0.47	GO:0005504	fatty acid binding
0.46	GO:0015643	toxic substance binding
0.44	GO:0019825	oxygen binding
0.42	GO:0051087	chaperone binding
0.41	GO:0019842	vitamin binding
0.41	GO:0042802	identical protein binding
0.39	GO:0050662	coenzyme binding
0.37	GO:0003677	DNA binding
0.37	GO:0046872	metal ion binding
0.33	GO:0019899	enzyme binding

0.73	GO:0005615	extracellular space
0.43	GO:0043209	myelin sheath
0.43	GO:1903561	extracellular vesicle
0.40	GO:0005783	endoplasmic reticulum
0.40	GO:0005794	Golgi apparatus
0.39	GO:0043234	protein complex
0.35	GO:0060417	yolk
0.33	GO:0005604	basement membrane
0.33	GO:0043233	organelle lumen
0.32	GO:0005634	nucleus

sp|P84520|ADA2_CHICK
Adenosine deaminase 2 (Fragment)
Search

0.10	Adenosine deaminase 2 (Fragment)

0.30	GO:0019637	organophosphate metabolic process
0.30	GO:0006807	nitrogen compound metabolic process
0.30	GO:0044281	small molecule metabolic process
0.30	GO:0046483	heterocycle metabolic process
0.30	GO:0006796	phosphate-containing compound metabolic process
0.30	GO:1901360	organic cyclic compound metabolic process
0.30	GO:0044238	primary metabolic process
0.30	GO:0006725	cellular aromatic compound metabolic process

0.30	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
0.30	GO:0019239	deaminase activity

0.30

EC:3.5

GO:0016810

sp|P84553|H1A2_CHICK
Histone H1.A2 (Fragment)
Search

sp|P85000|ISK1L_CHICK
Trypsin inhibitor ClTI-1
Search

SPINK2

0.95	Kazal-type serine proteinase inhibitor

0.71	GO:0010951	negative regulation of endopeptidase activity
0.63	GO:1902572	negative regulation of serine-type peptidase activity
0.63	GO:1900003	regulation of serine-type endopeptidase activity
0.56	GO:0060046	regulation of acrosome reaction
0.54	GO:0007286	spermatid development
0.51	GO:0010751	negative regulation of nitric oxide mediated signal transduction
0.50	GO:0090281	negative regulation of calcium ion import
0.49	GO:0002176	male germ cell proliferation
0.49	GO:2001256	regulation of store-operated calcium entry
0.49	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation

0.72	GO:0004867	serine-type endopeptidase inhibitor activity
0.44	GO:0032190	acrosin binding
0.43	GO:0008233	peptidase activity
0.42	GO:0002020	protease binding
0.40	GO:0043236	laminin binding
0.35	GO:0005509	calcium ion binding
0.35	GO:0090729	toxin activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

0.53	GO:0097223	sperm part
0.52	GO:0030141	secretory granule
0.51	GO:0005615	extracellular space
0.44	GO:0043005	neuron projection
0.44	GO:0097180	serine protease inhibitor complex
0.38	GO:1903561	extracellular vesicle
0.37	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005938	cell cortex
0.36	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0005829	cytosol

0.43

GO:0008233

sp|P86345|BORE2_CHICK
Borealin-2
Search

CDCA9

0.97	Borealin-2

0.74	GO:0000070	mitotic sister chromatid segregation
0.56	GO:0051301	cell division
0.53	GO:0051225	spindle assembly

0.84	GO:0032133	chromosome passenger complex
0.79	GO:0051233	spindle midzone
0.74	GO:0000775	chromosome, centromeric region
0.52	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P86346|BORE1_CHICK
Borealin
Search

CDCA8

0.84	Cell division cycle associated 8

0.79	GO:0007080	mitotic metaphase plate congression
0.50	GO:0051301	cell division

0.38

GO:0005515

protein binding

0.85	GO:0032133	chromosome passenger complex
0.79	GO:0045171	intercellular bridge
0.79	GO:0010369	chromocenter
0.77	GO:0030496	midbody
0.76	GO:0000775	chromosome, centromeric region
0.68	GO:0005730	nucleolus
0.65	GO:0051233	spindle midzone
0.36	GO:0005737	cytoplasm

sp|P87362|BLMH_CHICK
Bleomycin hydrolase
Search

BLMH

0.76	Bleomycin hydrolase

0.61	GO:0006508	proteolysis
0.49	GO:0043418	homocysteine catabolic process
0.48	GO:0042493	response to drug
0.48	GO:0009636	response to toxic substance
0.34	GO:0000209	protein polyubiquitination

0.75	GO:0004197	cysteine-type endopeptidase activity
0.50	GO:0042802	identical protein binding
0.37	GO:0004177	aminopeptidase activity
0.34	GO:0004180	carboxypeptidase activity

0.36	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.75

GO:0004197

tr|P87373|P87373_CHICK
BMP5
Search

BMP5

0.97	Bone morphogenetic protein 5

0.74	GO:0010469	regulation of receptor activity
0.63	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.61	GO:0032345	negative regulation of aldosterone metabolic process
0.61	GO:2000065	negative regulation of cortisol biosynthetic process
0.61	GO:0032347	regulation of aldosterone biosynthetic process
0.60	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway
0.59	GO:0003323	type B pancreatic cell development
0.59	GO:1900006	positive regulation of dendrite development
0.58	GO:2000105	positive regulation of DNA-dependent DNA replication
0.57	GO:1905069	allantois development

0.76	GO:0008083	growth factor activity
0.62	GO:0070700	BMP receptor binding
0.48	GO:0005160	transforming growth factor beta receptor binding
0.46	GO:0005125	cytokine activity
0.34	GO:0008201	heparin binding

0.65	GO:0005576	extracellular region
0.37	GO:0031982	vesicle
0.30	GO:0016020	membrane

sp|P87498|VIT1_CHICK
Vitellogenin-1
Search

VTG1

0.64	Vitellogenin As

0.74	GO:0006869	lipid transport
0.41	GO:0032355	response to estradiol
0.38	GO:1903165	response to polycyclic arene
0.37	GO:0071391	cellular response to estrogen stimulus
0.36	GO:0032868	response to insulin
0.36	GO:0009410	response to xenobiotic stimulus
0.36	GO:0034605	cellular response to heat
0.35	GO:0098869	cellular oxidant detoxification
0.35	GO:1905155	positive regulation of membrane invagination
0.35	GO:0060099	regulation of phagocytosis, engulfment

0.77	GO:0005319	lipid transporter activity
0.40	GO:0045735	nutrient reservoir activity
0.35	GO:0016209	antioxidant activity
0.35	GO:0005102	receptor binding
0.35	GO:0070891	lipoteichoic acid binding
0.34	GO:0001530	lipopolysaccharide binding
0.31	GO:0004594	pantothenate kinase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0060417	yolk
0.35	GO:0005615	extracellular space
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.31

EC:2.7.1.33

GO:0004594

sp|P98150|NFKB2_CHICK
Nuclear factor NF-kappa-B p100 subunit
Search

NFKB2

0.97	Nuclear factor kappa B subunit 2

0.59	GO:0007165	signal transduction
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0002268	follicular dendritic cell differentiation
0.56	GO:0010468	regulation of gene expression
0.55	GO:0002467	germinal center formation
0.54	GO:0048536	spleen development
0.52	GO:0051254	positive regulation of RNA metabolic process
0.51	GO:0010557	positive regulation of macromolecule biosynthetic process
0.51	GO:0031328	positive regulation of cellular biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.53	GO:0001067	regulatory region nucleic acid binding
0.47	GO:0003682	chromatin binding
0.40	GO:0042805	actinin binding
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0008134	transcription factor binding
0.38	GO:0046982	protein heterodimerization activity
0.34	GO:0003713	transcription coactivator activity

0.61	GO:0005634	nucleus
0.60	GO:0033256	I-kappaB/NF-kappaB complex
0.49	GO:0005829	cytosol
0.38	GO:0070013	intracellular organelle lumen
0.36	GO:0005739	mitochondrion
0.36	GO:0044446	intracellular organelle part
0.33	GO:0042581	specific granule
0.33	GO:0031983	vesicle lumen
0.32	GO:0005576	extracellular region

sp|P98152|TF65_CHICK
Transcription factor p65
Search

RELA

0.92	Nuclear transcription factor RelA

0.76	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.64	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.60	GO:0045893	positive regulation of transcription, DNA-templated
0.56	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.54	GO:0071224	cellular response to peptidoglycan
0.54	GO:0071316	cellular response to nicotine
0.54	GO:0045084	positive regulation of interleukin-12 biosynthetic process
0.54	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway
0.54	GO:2000630	positive regulation of miRNA metabolic process
0.54	GO:0006954	inflammatory response

0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.54	GO:0071532	ankyrin repeat binding
0.53	GO:0051059	NF-kappaB binding
0.52	GO:0003682	chromatin binding
0.52	GO:0070491	repressing transcription factor binding
0.51	GO:0047485	protein N-terminus binding
0.51	GO:0033613	activating transcription factor binding
0.51	GO:0042826	histone deacetylase binding
0.50	GO:0042805	actinin binding

0.81	GO:0071159	NF-kappaB complex
0.61	GO:0005634	nucleus
0.52	GO:0033256	I-kappaB/NF-kappaB complex
0.49	GO:0005829	cytosol
0.47	GO:0005667	transcription factor complex
0.46	GO:0000785	chromatin
0.44	GO:0070013	intracellular organelle lumen
0.33	GO:0030430	host cell cytoplasm
0.33	GO:0042025	host cell nucleus

0.34

EC:2.7.7.19

GO:0004652

sp|P98157|LRP1_CHICK
Low-density lipoprotein receptor-related protein 1
Search

LRP1

0.71	LDL receptor related protein 1

0.79	GO:1905167	positive regulation of lysosomal protein catabolic process
0.78	GO:0002265	astrocyte activation involved in immune response
0.78	GO:1900223	positive regulation of amyloid-beta clearance
0.78	GO:0097242	amyloid-beta clearance
0.75	GO:0045056	transcytosis
0.75	GO:1904646	cellular response to amyloid-beta
0.73	GO:1903078	positive regulation of protein localization to plasma membrane
0.72	GO:0032092	positive regulation of protein binding
0.71	GO:0045807	positive regulation of endocytosis
0.67	GO:0010942	positive regulation of cell death

0.81	GO:0016964	alpha-2 macroglobulin receptor activity
0.77	GO:0032050	clathrin heavy chain binding
0.76	GO:0034185	apolipoprotein binding
0.70	GO:0005509	calcium ion binding
0.64	GO:0032403	protein complex binding

0.70	GO:0016323	basolateral plasma membrane
0.68	GO:0005769	early endosome
0.67	GO:0043235	receptor complex
0.30	GO:0016021	integral component of membrane

sp|P98165|VLDLR_CHICK
Very low-density lipoprotein receptor
Search

VLDLR

0.74	Very low density lipoprotein receptor

0.72	GO:0006898	receptor-mediated endocytosis
0.55	GO:0034436	glycoprotein transport
0.55	GO:0034447	very-low-density lipoprotein particle clearance
0.53	GO:0038026	reelin-mediated signaling pathway
0.52	GO:1900006	positive regulation of dendrite development
0.51	GO:0021517	ventral spinal cord development
0.51	GO:0048813	dendrite morphogenesis
0.48	GO:0045860	positive regulation of protein kinase activity
0.48	GO:0000122	negative regulation of transcription by RNA polymerase II
0.36	GO:0008203	cholesterol metabolic process

0.86	GO:0030229	very-low-density lipoprotein particle receptor activity
0.69	GO:0005509	calcium ion binding
0.55	GO:0034437	glycoprotein transporter activity
0.55	GO:0038025	reelin receptor activity
0.55	GO:0034189	very-low-density lipoprotein particle binding
0.53	GO:0034185	apolipoprotein binding
0.52	GO:0048306	calcium-dependent protein binding
0.34	GO:0005041	low-density lipoprotein receptor activity
0.34	GO:0030296	protein tyrosine kinase activator activity

0.49	GO:0043235	receptor complex
0.46	GO:0005615	extracellular space
0.37	GO:1990777	lipoprotein particle
0.36	GO:0005905	clathrin-coated pit
0.33	GO:0005765	lysosomal membrane
0.33	GO:0045177	apical part of cell
0.33	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0009986	cell surface
0.32	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane

tr|Q001T8|Q001T8_CHICK
MAGE protein
Search

0.92	Melanoma-associated antigen G1

0.71	GO:0072711	cellular response to hydroxyurea
0.66	GO:0034644	cellular response to UV
0.65	GO:0031398	positive regulation of protein ubiquitination
0.64	GO:0070534	protein K63-linked ubiquitination
0.60	GO:0042147	retrograde transport, endosome to Golgi
0.60	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.59	GO:0051127	positive regulation of actin nucleation
0.58	GO:0042752	regulation of circadian rhythm
0.53	GO:0006281	DNA repair
0.52	GO:0048523	negative regulation of cellular process

0.57	GO:0005515	protein binding
0.56	GO:0004842	ubiquitin-protein transferase activity

0.64	GO:0030915	Smc5-Smc6 complex
0.61	GO:0030904	retromer complex
0.57	GO:0005768	endosome
0.53	GO:0005829	cytosol
0.49	GO:0005634	nucleus
0.45	GO:0000781	chromosome, telomeric region
0.41	GO:0070062	extracellular exosome
0.38	GO:0031974	membrane-enclosed lumen
0.30	GO:0016021	integral component of membrane

0.56

KEGG:R03876

GO:0004842

sp|Q00546|TENR_CHICK
Tenascin-R
Search

TNR

0.72	Tenascin R (Restrictin, janusin)

0.79	GO:0050767	regulation of neurogenesis
0.72	GO:0007155	cell adhesion
0.54	GO:0051971	positive regulation of transmission of nerve impulse
0.54	GO:0051968	positive regulation of synaptic transmission, glutamatergic
0.53	GO:0035641	locomotory exploration behavior
0.52	GO:0060291	long-term synaptic potentiation
0.52	GO:0050805	negative regulation of synaptic transmission
0.52	GO:0022029	telencephalon cell migration
0.52	GO:0050885	neuromuscular process controlling balance
0.52	GO:0010771	negative regulation of cell morphogenesis involved in differentiation

0.36	GO:0005178	integrin binding
0.34	GO:0046625	sphingolipid binding
0.34	GO:0042802	identical protein binding
0.33	GO:0045545	syndecan binding

0.76	GO:0005578	proteinaceous extracellular matrix
0.55	GO:0072534	perineuronal net
0.50	GO:0045121	membrane raft
0.48	GO:0009986	cell surface
0.35	GO:1990026	hippocampal mossy fiber expansion
0.35	GO:0097442	CA3 pyramidal cell dendrite
0.34	GO:0043025	neuronal cell body
0.32	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

sp|Q00649|HSPB1_CHICK
Heat shock protein beta-1
Search

HSPB1

0.90	LOW QUALITY PROTEIN: heat shock protein beta-1

0.85	GO:0099641	anterograde axonal protein transport
0.81	GO:0038033	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
0.81	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process
0.79	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.79	GO:0032731	positive regulation of interleukin-1 beta production
0.76	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.73	GO:0045766	positive regulation of angiogenesis
0.73	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling
0.73	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.72	GO:0061077	chaperone-mediated protein folding

0.84	GO:0008426	protein kinase C inhibitor activity
0.79	GO:0044183	protein binding involved in protein folding
0.78	GO:0005080	protein kinase C binding
0.69	GO:0042803	protein homodimerization activity
0.43	GO:0043130	ubiquitin binding
0.41	GO:0005212	structural constituent of eye lens
0.36	GO:0003723	RNA binding

0.77	GO:1904115	axon cytoplasm
0.75	GO:0030018	Z disc
0.61	GO:0005634	nucleus
0.51	GO:0005886	plasma membrane
0.50	GO:0005819	spindle
0.42	GO:0031012	extracellular matrix
0.41	GO:1905369	endopeptidase complex
0.41	GO:0005925	focal adhesion
0.41	GO:0070062	extracellular exosome
0.41	GO:0070013	intracellular organelle lumen

sp|Q00709|BCL2_CHICK
Apoptosis regulator Bcl-2
Search

BCL2

0.86	3-ketodihydrosphingosine reductase

0.78	GO:0043066	negative regulation of apoptotic process
0.74	GO:0006915	apoptotic process
0.62	GO:0032848	negative regulation of cellular pH reduction
0.61	GO:0043375	CD8-positive, alpha-beta T cell lineage commitment
0.60	GO:0014042	positive regulation of neuron maturation
0.60	GO:0021747	cochlear nucleus development
0.60	GO:0002326	B cell lineage commitment
0.60	GO:0046671	negative regulation of retinal cell programmed cell death
0.60	GO:0045636	positive regulation of melanocyte differentiation
0.59	GO:0038034	signal transduction in absence of ligand

0.59	GO:0051434	BH3 domain binding
0.57	GO:0051721	protein phosphatase 2A binding
0.55	GO:0002020	protease binding
0.55	GO:0016248	channel inhibitor activity
0.53	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0046982	protein heterodimerization activity
0.52	GO:0042803	protein homodimerization activity
0.50	GO:0008134	transcription factor binding
0.48	GO:0022803	passive transmembrane transporter activity
0.46	GO:0043565	sequence-specific DNA binding

0.55	GO:0043209	myelin sheath
0.55	GO:0031965	nuclear membrane
0.54	GO:0005741	mitochondrial outer membrane
0.52	GO:0046930	pore complex
0.51	GO:0005789	endoplasmic reticulum membrane
0.49	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0097136	Bcl-2 family protein complex
0.33	GO:0005813	centrosome

0.31

EC:1

GO:0016491

sp|Q00944|FAK1_CHICK
Focal adhesion kinase 1
Search

PTK2

0.83	Focal ashension kinase 1

0.85	GO:0007172	signal complex assembly
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.60	GO:0007165	signal transduction
0.44	GO:2000811	negative regulation of anoikis
0.44	GO:0010613	positive regulation of cardiac muscle hypertrophy
0.44	GO:0051964	negative regulation of synapse assembly
0.44	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.44	GO:0071378	cellular response to growth hormone stimulus
0.44	GO:0046621	negative regulation of organ growth
0.44	GO:0033628	regulation of cell adhesion mediated by integrin

0.77	GO:0004713	protein tyrosine kinase activity
0.64	GO:0004871	signal transducer activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0008432	JUN kinase binding
0.44	GO:0042169	SH2 domain binding
0.40	GO:0003779	actin binding
0.39	GO:0005178	integrin binding

0.81	GO:0005925	focal adhesion
0.68	GO:0005856	cytoskeleton
0.42	GO:0030027	lamellipodium
0.42	GO:0016324	apical plasma membrane
0.40	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.40	GO:0005829	cytosol
0.39	GO:0042383	sarcolemma
0.38	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005634	nucleus
0.37	GO:0014704	intercalated disc

0.77

EC:2.7.10

GO:0004713

tr|Q00G66|Q00G66_CHICK
Shox
Search

SHOX

0.95	Short stature homeobox transcript variant SHOXa

0.62	GO:0007275	multicellular organism development
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.49	GO:0001503	ossification
0.47	GO:2000172	regulation of branching morphogenesis of a nerve
0.47	GO:0048743	positive regulation of skeletal muscle fiber development
0.46	GO:1902680	positive regulation of RNA biosynthetic process
0.46	GO:0009888	tissue development
0.46	GO:0002053	positive regulation of mesenchymal cell proliferation

0.63	GO:0043565	sequence-specific DNA binding
0.43	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.34	GO:0005515	protein binding
0.34	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.41	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part

sp|Q01406|SRC8_CHICK
Src substrate protein p85
Search

CTTN

0.51	src substrate cortactin

0.84	GO:0030041	actin filament polymerization
0.66	GO:0097062	dendritic spine maintenance
0.66	GO:0006930	substrate-dependent cell migration, cell extension
0.64	GO:0045987	positive regulation of smooth muscle contraction
0.63	GO:1903146	regulation of autophagy of mitochondrion
0.62	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.59	GO:0030838	positive regulation of actin filament polymerization
0.53	GO:0006886	intracellular protein transport
0.41	GO:0048041	focal adhesion assembly
0.41	GO:0097581	lamellipodium organization

0.66	GO:0005522	profilin binding
0.60	GO:0045296	cadherin binding

0.63	GO:0002102	podosome
0.62	GO:1990023	mitotic spindle midzone
0.61	GO:0001726	ruffle
0.61	GO:0005884	actin filament
0.60	GO:0030027	lamellipodium
0.59	GO:0030863	cortical cytoskeleton
0.58	GO:0008076	voltage-gated potassium channel complex
0.54	GO:0005794	Golgi apparatus
0.52	GO:0005829	cytosol
0.40	GO:0043197	dendritic spine

sp|Q01635|LAMB1_CHICK
Laminin subunit beta-1 (Fragment)
Search

LAMB1

0.49	Laminin subunit beta 1

0.86	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration
0.84	GO:0034446	substrate adhesion-dependent cell spreading
0.83	GO:0035987	endodermal cell differentiation
0.79	GO:0042476	odontogenesis
0.79	GO:0030335	positive regulation of cell migration
0.78	GO:0031175	neuron projection development
0.47	GO:0007162	negative regulation of cell adhesion
0.46	GO:0030198	extracellular matrix organization
0.45	GO:0007566	embryo implantation
0.44	GO:0060429	epithelium development

0.80	GO:0005201	extracellular matrix structural constituent
0.47	GO:0005178	integrin binding
0.47	GO:0043208	glycosphingolipid binding
0.41	GO:0019899	enzyme binding

0.87	GO:0043257	laminin-8 complex
0.87	GO:0005607	laminin-2 complex
0.87	GO:0005606	laminin-1 complex
0.87	GO:0043259	laminin-10 complex
0.72	GO:0005615	extracellular space
0.50	GO:0048471	perinuclear region of cytoplasm
0.43	GO:1903561	extracellular vesicle
0.41	GO:0005608	laminin-3 complex
0.40	GO:0043083	synaptic cleft
0.40	GO:0005788	endoplasmic reticulum lumen

sp|Q01636|LAMBV_CHICK
Laminin subunit beta-1 variant (Fragment)
Search

0.11	Laminin subunit beta-1 variant (Fragment)

0.79	GO:0042063	gliogenesis
0.76	GO:0072274	metanephric glomerular basement membrane development
0.76	GO:0000904	cell morphogenesis involved in differentiation
0.75	GO:0007417	central nervous system development
0.75	GO:0031175	neuron projection development
0.75	GO:0072313	metanephric glomerular epithelial cell development
0.75	GO:0072248	metanephric glomerular visceral epithelial cell differentiation
0.72	GO:0072015	glomerular visceral epithelial cell development
0.70	GO:0048678	response to axon injury
0.68	GO:0007528	neuromuscular junction development

0.70	GO:0005178	integrin binding
0.62	GO:0005201	extracellular matrix structural constituent
0.43	GO:0043208	glycosphingolipid binding
0.38	GO:0019899	enzyme binding
0.37	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity

0.85	GO:0043256	laminin complex
0.71	GO:0043083	synaptic cleft
0.70	GO:0005615	extracellular space
0.44	GO:1903561	extracellular vesicle
0.44	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0005788	endoplasmic reticulum lumen
0.36	GO:0005634	nucleus

0.37

GO:0036459

sp|Q01741|CP1A2_CHICK
Cytochrome P450 1A2 (Fragment)
Search

sp|Q01795|MYF6_CHICK
Myogenic factor 6
Search

MYF6

0.86	Myogenic regulation factor 4

0.81	GO:0007517	muscle organ development
0.61	GO:0014706	striated muscle tissue development
0.57	GO:0001756	somitogenesis
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0006366	transcription by RNA polymerase II
0.54	GO:0048743	positive regulation of skeletal muscle fiber development
0.54	GO:1902680	positive regulation of RNA biosynthetic process
0.54	GO:0048729	tissue morphogenesis

0.68	GO:0046983	protein dimerization activity
0.58	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.55	GO:0003677	DNA binding
0.50	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0003682	chromatin binding
0.33	GO:0004725	protein tyrosine phosphatase activity

0.61	GO:0005634	nucleus
0.39	GO:0070013	intracellular organelle lumen
0.37	GO:0044446	intracellular organelle part
0.37	GO:0005667	transcription factor complex
0.35	GO:0032993	protein-DNA complex
0.30	GO:0016020	membrane

0.33

EC:3.1.3.48

GO:0004725

sp|Q01841|TGM2_CHICK
Protein-glutamine gamma-glutamyltransferase 2
Search

TGM2

0.50	Tissue-type transglutaminase

0.84	GO:0018149	peptide cross-linking
0.60	GO:0060662	salivary gland cavitation
0.59	GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration
0.59	GO:0051561	positive regulation of mitochondrial calcium ion concentration
0.59	GO:0060445	branching involved in salivary gland morphogenesis
0.57	GO:0043277	apoptotic cell clearance
0.53	GO:0043065	positive regulation of apoptotic process
0.52	GO:0045785	positive regulation of cell adhesion
0.41	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
0.40	GO:0001974	blood vessel remodeling

0.84	GO:0003810	protein-glutamine gamma-glutamyltransferase activity
0.38	GO:0019904	protein domain specific binding
0.37	GO:0032550	purine ribonucleoside binding
0.37	GO:0019001	guanyl nucleotide binding
0.36	GO:0019899	enzyme binding
0.35	GO:0046872	metal ion binding
0.35	GO:0008483	transaminase activity
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0098772	molecular function regulator

0.49	GO:0005783	endoplasmic reticulum
0.48	GO:0005829	cytosol
0.47	GO:0031226	intrinsic component of plasma membrane
0.45	GO:0005739	mitochondrion
0.37	GO:0005925	focal adhesion
0.37	GO:0031012	extracellular matrix
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.84

EC:2.3.2.13

GO:0003810

sp|Q02011|CNTF_CHICK
Ciliary neurotrophic factor
Search

CNTF

0.88	Ciliary neurotrophic factor

0.78	GO:0040007	growth
0.67	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway
0.66	GO:0046533	negative regulation of photoreceptor cell differentiation
0.65	GO:0046668	regulation of retinal cell programmed cell death
0.63	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.62	GO:0048644	muscle organ morphogenesis
0.62	GO:0043524	negative regulation of neuron apoptotic process
0.59	GO:0008284	positive regulation of cell proliferation
0.58	GO:0048666	neuron development
0.57	GO:0010469	regulation of receptor activity

0.65	GO:0005138	interleukin-6 receptor binding
0.58	GO:0008083	growth factor activity
0.50	GO:0005127	ciliary neurotrophic factor receptor binding
0.46	GO:0005125	cytokine activity

0.67	GO:0097058	CRLF-CLCF1 complex
0.49	GO:0005737	cytoplasm
0.46	GO:0030424	axon

sp|Q02020|FIBB_CHICK
Fibrinogen beta chain (Fragment)
Search

FGB

0.71	Fibrinogen B-beta subunit

0.82	GO:0007596	blood coagulation
0.70	GO:0001775	cell activation
0.68	GO:0051258	protein polymerization
0.66	GO:0043152	induction of bacterial agglutination
0.65	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.64	GO:0042730	fibrinolysis
0.63	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.63	GO:0045907	positive regulation of vasoconstriction
0.63	GO:2000352	negative regulation of endothelial cell apoptotic process
0.63	GO:0031639	plasminogen activation

0.71	GO:0030674	protein binding, bridging
0.64	GO:0005102	receptor binding
0.59	GO:0050839	cell adhesion molecule binding
0.57	GO:0051087	chaperone binding
0.48	GO:0005198	structural molecule activity
0.33	GO:0046872	metal ion binding

0.77	GO:0005577	fibrinogen complex
0.63	GO:0031091	platelet alpha granule
0.59	GO:0009897	external side of plasma membrane
0.56	GO:0005938	cell cortex
0.53	GO:0005783	endoplasmic reticulum
0.40	GO:0072562	blood microparticle
0.37	GO:0070062	extracellular exosome
0.36	GO:0034774	secretory granule lumen

sp|Q02092|GHR_CHICK
Growth hormone receptor
Search

GHR

0.64	Liver growth hormone receptor

0.75	GO:0019221	cytokine-mediated signaling pathway
0.42	GO:0006897	endocytosis
0.42	GO:0060396	growth hormone receptor signaling pathway
0.40	GO:0042976	activation of Janus kinase activity
0.39	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.39	GO:0007259	JAK-STAT cascade
0.38	GO:0000187	activation of MAPK activity
0.38	GO:0009410	response to xenobiotic stimulus
0.38	GO:0051094	positive regulation of developmental process
0.38	GO:0048009	insulin-like growth factor receptor signaling pathway

0.77	GO:0004896	cytokine receptor activity
0.39	GO:0017046	peptide hormone binding
0.38	GO:0042169	SH2 domain binding
0.37	GO:0019901	protein kinase binding
0.37	GO:0019903	protein phosphatase binding
0.37	GO:0019838	growth factor binding
0.37	GO:0070064	proline-rich region binding
0.36	GO:0042803	protein homodimerization activity

0.49	GO:0036464	cytoplasmic ribonucleoprotein granule
0.45	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.40	GO:0005576	extracellular region
0.39	GO:0070195	growth hormone receptor complex
0.37	GO:0043025	neuronal cell body
0.36	GO:0009986	cell surface
0.35	GO:0031904	endosome lumen
0.35	GO:0019898	extrinsic component of membrane
0.35	GO:0005634	nucleus

sp|Q02173|MPSF_CHICK
M-protein, striated muscle
Search

MYOM2

0.97	M-protein, striated muscle

0.80	GO:0006936	muscle contraction
0.68	GO:0071688	striated muscle myosin thick filament assembly
0.65	GO:0045214	sarcomere organization
0.58	GO:0007015	actin filament organization
0.48	GO:0002074	extraocular skeletal muscle development
0.38	GO:0010737	protein kinase A signaling
0.37	GO:0050714	positive regulation of protein secretion
0.36	GO:0010628	positive regulation of gene expression

0.75	GO:0019900	kinase binding
0.68	GO:0097493	structural molecule activity conferring elasticity
0.68	GO:0051371	muscle alpha-actinin binding
0.66	GO:0008307	structural constituent of muscle
0.60	GO:0051015	actin filament binding
0.43	GO:0005200	structural constituent of cytoskeleton
0.36	GO:0042803	protein homodimerization activity

0.85	GO:0031430	M band
0.67	GO:0005859	muscle myosin complex
0.64	GO:0030018	Z disc
0.40	GO:0032982	myosin filament
0.37	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

sp|Q02391|GSLG1_CHICK
Golgi apparatus protein 1
Search

GLG1

0.94	Putative golgi apparatus protein cysteine-rich fibroblast growth factor receptor

0.54	GO:0010955	negative regulation of protein processing
0.54	GO:0032330	regulation of chondrocyte differentiation
0.53	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.53	GO:0060349	bone morphogenesis
0.35	GO:0050900	leukocyte migration
0.34	GO:0006886	intracellular protein transport

0.49	GO:0017134	fibroblast growth factor binding
0.34	GO:0005102	receptor binding
0.32	GO:0003676	nucleic acid binding

0.73	GO:0000139	Golgi membrane
0.49	GO:0005578	proteinaceous extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:0005797	Golgi medial cisterna
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q02440|MYO5A_CHICK
Unconventional myosin-Va
Search

MYO5A

0.85	Unconventional myosin-Va

0.74	GO:0007018	microtubule-based movement
0.50	GO:0099089	establishment of endoplasmic reticulum localization to postsynapse
0.49	GO:0032252	secretory granule localization
0.49	GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
0.48	GO:0031987	locomotion involved in locomotory behavior
0.48	GO:0030050	vesicle transport along actin filament
0.47	GO:0030318	melanocyte differentiation
0.47	GO:0030073	insulin secretion
0.47	GO:0032400	melanosome localization
0.47	GO:0042759	long-chain fatty acid biosynthetic process

0.75	GO:0051015	actin filament binding
0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0000146	microfilament motor activity
0.47	GO:0097718	disordered domain specific binding
0.45	GO:0005516	calmodulin binding

0.77	GO:0016459	myosin complex
0.49	GO:0032593	insulin-responsive compartment
0.48	GO:0032433	filopodium tip
0.47	GO:0035371	microtubule plus-end
0.47	GO:0042470	melanosome
0.46	GO:0042641	actomyosin
0.46	GO:0005884	actin filament
0.46	GO:0001750	photoreceptor outer segment
0.46	GO:0001726	ruffle
0.46	GO:0055037	recycling endosome

sp|Q02814|HMD2_CHICK
Homeobox protein CHOX-CAD2 (Fragment)
Search

0.12	Homeobox protein CHOX-CAD2 (Fragment)

0.68	GO:0007275	multicellular organism development
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0009653	anatomical structure morphogenesis
0.51	GO:0003006	developmental process involved in reproduction
0.51	GO:0014807	regulation of somitogenesis
0.50	GO:0060429	epithelium development
0.49	GO:0030154	cell differentiation
0.49	GO:0035019	somatic stem cell population maintenance

0.60	GO:0043565	sequence-specific DNA binding
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.51	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.49	GO:0035326	enhancer binding
0.47	GO:0003714	transcription corepressor activity
0.42	GO:0003682	chromatin binding
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.47	GO:0017053	transcriptional repressor complex
0.46	GO:0000793	condensed chromosome
0.43	GO:0043233	organelle lumen
0.40	GO:0043234	protein complex
0.39	GO:0044446	intracellular organelle part

sp|Q02960|MIF_CHICK
Macrophage migration inhibitory factor
Search

MIF

0.85	Macrophage migration inhibitory factor

0.77	GO:0010760	negative regulation of macrophage chemotaxis
0.76	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.76	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
0.75	GO:0010739	positive regulation of protein kinase A signaling
0.74	GO:0090344	negative regulation of cell aging
0.74	GO:0070207	protein homotrimerization
0.74	GO:0048146	positive regulation of fibroblast proliferation
0.74	GO:0071157	negative regulation of cell cycle arrest
0.74	GO:0046457	prostanoid biosynthetic process
0.74	GO:0030890	positive regulation of B cell proliferation

0.85	GO:0050178	phenylpyruvate tautomerase activity
0.83	GO:0004167	dopachrome isomerase activity
0.75	GO:0042056	chemoattractant activity
0.73	GO:0005125	cytokine activity
0.67	GO:0005126	cytokine receptor binding
0.65	GO:0002020	protease binding
0.63	GO:0042802	identical protein binding
0.52	GO:0042289	MHC class II protein binding
0.37	GO:0032403	protein complex binding
0.33	GO:0003676	nucleic acid binding

0.67	GO:0005615	extracellular space
0.65	GO:0009986	cell surface
0.64	GO:0043209	myelin sheath
0.60	GO:0005654	nucleoplasm
0.59	GO:0005829	cytosol
0.41	GO:1903561	extracellular vesicle
0.39	GO:1904813	ficolin-1-rich granule lumen
0.39	GO:0034774	secretory granule lumen

0.85	EC:5.3.2.1	GO:0050178
0.83	KEGG:R03673	GO:0004167

sp|Q02977|YRK_CHICK
Proto-oncogene tyrosine-protein kinase Yrk
Search

FYN

0.58	Tyrosine-protein kinase Fyn

0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.55	GO:0046777	protein autophosphorylation
0.53	GO:0016477	cell migration
0.52	GO:1902951	negative regulation of dendritic spine maintenance
0.52	GO:0050852	T cell receptor signaling pathway
0.52	GO:0050798	activated T cell proliferation
0.51	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain
0.51	GO:0036120	cellular response to platelet-derived growth factor stimulus
0.51	GO:0090314	positive regulation of protein targeting to membrane
0.51	GO:1904645	response to amyloid-beta

0.80	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0044325	ion channel binding
0.50	GO:0097718	disordered domain specific binding
0.50	GO:0046875	ephrin receptor binding
0.49	GO:0070851	growth factor receptor binding
0.48	GO:0001664	G-protein coupled receptor binding

0.49	GO:0014069	postsynaptic density
0.48	GO:0005884	actin filament
0.48	GO:0098857	membrane microdomain
0.48	GO:0030425	dendrite
0.47	GO:0005829	cytosol
0.46	GO:0005768	endosome
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.40	GO:0016235	aggresome
0.40	GO:0032587	ruffle membrane
0.38	GO:0005634	nucleus

0.80	EC:2.7.10.2	GO:0004715
0.35	KEGG:R04545	GO:0046934

sp|Q03237|MYBB_CHICK
Myb-related protein B
Search

MYBL2

0.97	MYB proto-oncogene like 2

0.56	GO:0090307	mitotic spindle assembly
0.55	GO:1990830	cellular response to leukemia inhibitory factor
0.52	GO:0006366	transcription by RNA polymerase II
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.44	GO:0030154	cell differentiation
0.38	GO:0043525	positive regulation of neuron apoptotic process
0.34	GO:0051726	regulation of cell cycle
0.33	GO:1990511	piRNA biosynthetic process
0.33	GO:0010529	negative regulation of transposition
0.33	GO:0007141	male meiosis I

0.55	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0003677	DNA binding
0.53	GO:0001067	regulatory region nucleic acid binding
0.49	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.34	GO:0005515	protein binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0005524	ATP binding

0.58	GO:0031523	Myb complex
0.48	GO:0005654	nucleoplasm

0.33

GO:0004674

sp|Q03352|ANT3_CHICK
Antithrombin-III (Fragment)
Search

0.77	Antithrombin-III (Fragment)

0.86	GO:2000266	regulation of blood coagulation, intrinsic pathway
0.76	GO:0010951	negative regulation of endopeptidase activity
0.45	GO:0007596	blood coagulation
0.44	GO:0002438	acute inflammatory response to antigenic stimulus
0.43	GO:0007595	lactation
0.42	GO:0007584	response to nutrient
0.41	GO:0042129	regulation of T cell proliferation
0.39	GO:0010608	posttranscriptional regulation of gene expression
0.37	GO:0002635	negative regulation of germinal center formation
0.37	GO:0061470	T follicular helper cell differentiation

0.81	GO:0008201	heparin binding
0.79	GO:0004867	serine-type endopeptidase inhibitor activity
0.62	GO:0002020	protease binding
0.56	GO:0042802	identical protein binding
0.41	GO:0003730	mRNA 3'-UTR binding
0.36	GO:0035613	RNA stem-loop binding
0.35	GO:0046872	metal ion binding
0.34	GO:0016874	ligase activity

0.72	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.36	GO:0005788	endoplasmic reticulum lumen
0.36	GO:0000932	P-body
0.36	GO:0010494	cytoplasmic stress granule
0.33	GO:0005886	plasma membrane

0.34

GO:0016874

tr|Q03481|Q03481_CHICK
Alpha8 subunit of nicotinic acetylcholine receptor
Search

CHRNA7

0.86	Nicotinic acetylcholine receptor subunit alpha 7

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.46	GO:0035094	response to nicotine
0.46	GO:1905920	positive regulation of CoA-transferase activity
0.45	GO:0032720	negative regulation of tumor necrosis factor production
0.45	GO:0001988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure
0.45	GO:0050893	sensory processing
0.45	GO:0060112	generation of ovulation cycle rhythm
0.45	GO:0140059	dendrite arborization
0.44	GO:1905906	regulation of amyloid fibril formation

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.41	GO:0017081	chloride channel regulator activity
0.41	GO:0042166	acetylcholine binding
0.40	GO:0001540	amyloid-beta binding
0.40	GO:0015643	toxic substance binding
0.38	GO:0042803	protein homodimerization activity
0.35	GO:0008179	adenylate cyclase binding
0.35	GO:0097110	scaffold protein binding
0.34	GO:0051117	ATPase binding

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.60	GO:0043204	perikaryon
0.59	GO:0030424	axon
0.57	GO:0030425	dendrite
0.43	GO:0032589	neuron projection membrane
0.41	GO:0009897	external side of plasma membrane
0.41	GO:0016324	apical plasma membrane
0.41	GO:0005892	acetylcholine-gated channel complex
0.40	GO:0005737	cytoplasm

sp|Q03669|AT2A2_CHICK
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
Search

ATP2A2

0.53	Calcium-transporting ATPase

0.76	GO:0070588	calcium ion transmembrane transport
0.68	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.57	GO:0032470	positive regulation of endoplasmic reticulum calcium ion concentration
0.57	GO:1903233	regulation of calcium ion-dependent exocytosis of neurotransmitter
0.56	GO:0033292	T-tubule organization
0.56	GO:0014883	transition between fast and slow fiber
0.55	GO:0070296	sarcoplasmic reticulum calcium ion transport
0.55	GO:0008016	regulation of heart contraction
0.55	GO:0003299	muscle hypertrophy in response to stress
0.55	GO:0014887	cardiac muscle adaptation

0.80	GO:0005388	calcium-transporting ATPase activity
0.54	GO:0044548	S100 protein binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0019899	enzyme binding
0.47	GO:0005509	calcium ion binding
0.39	GO:0031775	lutropin-choriogonadotropic hormone receptor binding
0.37	GO:0008022	protein C-terminus binding

0.56	GO:0097470	ribbon synapse
0.54	GO:0016529	sarcoplasmic reticulum
0.48	GO:0005789	endoplasmic reticulum membrane
0.47	GO:0005654	nucleoplasm
0.39	GO:0098588	bounding membrane of organelle
0.39	GO:0090534	calcium ion-transporting ATPase complex
0.38	GO:0014704	intercalated disc
0.37	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0012506	vesicle membrane

0.80

EC:3.6.3.8

GO:0005388

sp|Q03696|NGCA_CHICK
Neuronal-glial cell adhesion molecule
Search

L1CAM

0.89	Neuronal-glial cell adhesion molecule

0.52	GO:0007411	axon guidance
0.51	GO:0007160	cell-matrix adhesion
0.51	GO:0050808	synapse organization
0.50	GO:0016477	cell migration
0.41	GO:0010975	regulation of neuron projection development
0.40	GO:0061387	regulation of extent of cell growth
0.40	GO:0010770	positive regulation of cell morphogenesis involved in differentiation
0.40	GO:0030307	positive regulation of cell growth
0.40	GO:0048639	positive regulation of developmental growth
0.40	GO:0031346	positive regulation of cell projection organization

0.49	GO:0019904	protein domain specific binding
0.40	GO:0050839	cell adhesion molecule binding
0.39	GO:0030506	ankyrin binding
0.38	GO:0086080	protein binding involved in heterotypic cell-cell adhesion
0.38	GO:0033691	sialic acid binding
0.37	GO:0043621	protein self-association
0.36	GO:0032403	protein complex binding
0.36	GO:0042802	identical protein binding
0.36	GO:0005102	receptor binding

0.55	GO:0030424	axon
0.51	GO:0043025	neuronal cell body
0.49	GO:0009986	cell surface
0.48	GO:0031012	extracellular matrix
0.46	GO:0030426	growth cone
0.42	GO:0005886	plasma membrane
0.38	GO:0045202	synapse
0.37	GO:0044306	neuron projection terminus
0.37	GO:0005925	focal adhesion
0.37	GO:0030425	dendrite

sp|Q04205|TENS_CHICK
Tensin
Search

TNS1

0.79

Tensin

0.59	GO:0010761	fibroblast migration
0.58	GO:0035556	intracellular signal transduction
0.57	GO:0007044	cell-substrate junction assembly

0.48	GO:0003779	actin binding
0.46	GO:0046872	metal ion binding
0.34	GO:0003723	RNA binding

0.59	GO:0005912	adherens junction
0.56	GO:0030055	cell-substrate junction
0.44	GO:0009986	cell surface
0.44	GO:0005622	intracellular
0.39	GO:0043228	non-membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q04584|ZYX_CHICK
Zyxin
Search

ZYX

0.83	LIM domain containing preferred translocation partner in lipoma

0.52	GO:0043149	stress fiber assembly
0.51	GO:0071346	cellular response to interferon-gamma
0.50	GO:0007179	transforming growth factor beta receptor signaling pathway
0.49	GO:0007160	cell-matrix adhesion
0.48	GO:0007229	integrin-mediated signaling pathway
0.42	GO:0045805	positive regulation of eclosion
0.42	GO:0048526	imaginal disc-derived wing expansion
0.41	GO:0035002	liquid clearance, open tracheal system
0.41	GO:0045572	positive regulation of imaginal disc growth
0.41	GO:0007430	terminal branching, open tracheal system

0.53	GO:0046872	metal ion binding
0.40	GO:0051393	alpha-actinin binding
0.34	GO:0004222	metalloendopeptidase activity
0.33	GO:0008134	transcription factor binding
0.33	GO:0003723	RNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0097517	contractile actin filament bundle
0.54	GO:0042641	actomyosin
0.52	GO:0005925	focal adhesion
0.50	GO:0045335	phagocytic vesicle
0.50	GO:0005913	cell-cell adherens junction
0.45	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.41	GO:0035003	subapical complex
0.32	GO:0005887	integral component of plasma membrane

0.34

GO:0004222

sp|Q04594|PRLR_CHICK
Prolactin receptor
Search

PRLR

0.61	Prolactin receptor long form

0.85	GO:0038161	prolactin signaling pathway
0.59	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity
0.50	GO:0007595	lactation
0.50	GO:0060736	prostate gland growth
0.50	GO:0060644	mammary gland epithelial cell differentiation
0.50	GO:0061377	mammary gland lobule development
0.49	GO:0007259	JAK-STAT cascade
0.48	GO:0030856	regulation of epithelial cell differentiation
0.45	GO:0030155	regulation of cell adhesion
0.39	GO:0042976	activation of Janus kinase activity

0.85	GO:0004925	prolactin receptor activity
0.57	GO:0017046	peptide hormone binding
0.37	GO:0046872	metal ion binding
0.37	GO:0042803	protein homodimerization activity
0.36	GO:0042978	ornithine decarboxylase activator activity
0.35	GO:0019901	protein kinase binding

0.52	GO:0009986	cell surface
0.37	GO:0031904	endosome lumen
0.36	GO:0005886	plasma membrane
0.34	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|Q04619|HS90B_CHICK
Heat shock cognate protein HSP 90-beta
Search

HSP90AB1

0.71	Heat shock cognate protein HSP 90-beta

0.69	GO:0006457	protein folding
0.62	GO:0006950	response to stress
0.58	GO:1901389	negative regulation of transforming growth factor beta activation
0.56	GO:1905323	telomerase holoenzyme complex assembly
0.55	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.55	GO:0071157	negative regulation of cell cycle arrest
0.55	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.54	GO:0032516	positive regulation of phosphoprotein phosphatase activity
0.54	GO:2000010	positive regulation of protein localization to cell surface
0.54	GO:0043627	response to estrogen

0.71	GO:0051082	unfolded protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.55	GO:0043008	ATP-dependent protein binding
0.54	GO:1990226	histone methyltransferase binding
0.54	GO:0070182	DNA polymerase binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0097718	disordered domain specific binding
0.52	GO:0042826	histone deacetylase binding

0.54	GO:0034751	aryl hydrocarbon receptor complex
0.50	GO:0008180	COP9 signalosome
0.46	GO:0005576	extracellular region
0.46	GO:0005829	cytosol
0.43	GO:0042470	melanosome
0.42	GO:1990917	ooplasm
0.42	GO:0097524	sperm plasma membrane
0.41	GO:0005739	mitochondrion
0.41	GO:0061827	sperm head
0.41	GO:0031526	brush border membrane

0.34

EC:2.7.10

GO:0004713

sp|Q04678|SSRP1_CHICK
FACT complex subunit SSRP1
Search

SSRP1

0.75	FACT complex subunit SSRP1

0.66	GO:0006260	DNA replication
0.64	GO:0006281	DNA repair
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.36	GO:0051726	regulation of cell cycle
0.35	GO:1901796	regulation of signal transduction by p53 class mediator

0.54	GO:0003677	DNA binding
0.53	GO:0003682	chromatin binding
0.34	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.67	GO:0005694	chromosome
0.61	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q04861|NFKB1_CHICK
Nuclear factor NF-kappa-B p105 subunit
Search

NFKB1

0.96	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.60	GO:0045083	negative regulation of interleukin-12 biosynthetic process
0.59	GO:0007165	signal transduction
0.59	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity
0.59	GO:1900127	positive regulation of hyaluronan biosynthetic process
0.59	GO:0071316	cellular response to nicotine
0.58	GO:2000630	positive regulation of miRNA metabolic process
0.57	GO:0071354	cellular response to interleukin-6
0.57	GO:0035994	response to muscle stretch
0.56	GO:1904385	cellular response to angiotensin

0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.54	GO:0042805	actinin binding
0.53	GO:0003682	chromatin binding
0.50	GO:0042803	protein homodimerization activity
0.50	GO:0046982	protein heterodimerization activity
0.50	GO:0008134	transcription factor binding
0.33	GO:0031072	heat shock protein binding

0.61	GO:0005634	nucleus
0.49	GO:0005829	cytosol
0.47	GO:0070013	intracellular organelle lumen
0.47	GO:0033256	I-kappaB/NF-kappaB complex
0.44	GO:0005739	mitochondrion
0.43	GO:0044446	intracellular organelle part
0.35	GO:0042581	specific granule
0.35	GO:0031983	vesicle lumen
0.33	GO:0005576	extracellular region
0.33	GO:0043005	neuron projection

sp|Q04929|CRK_CHICK
Adapter molecule crk
Search

CRK

0.93	Adapter molecule crk

0.81	GO:0071538	SH2 domain-mediated complex assembly
0.75	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.74	GO:0061045	negative regulation of wound healing
0.74	GO:0048013	ephrin receptor signaling pathway
0.71	GO:0032956	regulation of actin cytoskeleton organization
0.71	GO:0043393	regulation of protein binding
0.71	GO:2000146	negative regulation of cell motility
0.69	GO:0009967	positive regulation of signal transduction
0.66	GO:0043087	regulation of GTPase activity
0.61	GO:0008360	regulation of cell shape

0.79	GO:0042169	SH2 domain binding
0.78	GO:0046875	ephrin receptor binding
0.77	GO:0005070	SH3/SH2 adaptor activity
0.77	GO:0045309	protein phosphorylated amino acid binding
0.75	GO:1990782	protein tyrosine kinase binding
0.73	GO:0043621	protein self-association
0.69	GO:0017124	SH3 domain binding
0.51	GO:0005159	insulin-like growth factor receptor binding
0.51	GO:0097110	scaffold protein binding
0.47	GO:0008092	cytoskeletal protein binding

0.66	GO:0015629	actin cytoskeleton
0.56	GO:0043234	protein complex
0.48	GO:0098857	membrane microdomain
0.41	GO:0070062	extracellular exosome
0.39	GO:0005886	plasma membrane
0.38	GO:0005829	cytosol
0.38	GO:0044430	cytoskeletal part
0.35	GO:0019028	viral capsid
0.35	GO:0005634	nucleus

sp|Q04982|BRAF_CHICK
Serine/threonine-protein kinase B-raf
Search

BRAF

0.97	Serine/threonine-protein kinase B-raf

0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.57	GO:2000301	negative regulation of synaptic vesicle exocytosis
0.57	GO:0002318	myeloid progenitor cell differentiation
0.57	GO:0010764	negative regulation of fibroblast migration
0.56	GO:0048680	positive regulation of axon regeneration
0.56	GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment
0.56	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.55	GO:0030878	thyroid gland development
0.55	GO:2000352	negative regulation of endothelial cell apoptotic process

0.77	GO:0005057	signal transducer activity, downstream of receptor
0.69	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0046872	metal ion binding
0.50	GO:0031434	mitogen-activated protein kinase kinase binding
0.49	GO:0042802	identical protein binding
0.36	GO:0031267	small GTPase binding

0.52	GO:0044297	cell body
0.51	GO:0043005	neuron projection
0.47	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.42	GO:0005886	plasma membrane
0.36	GO:0005634	nucleus
0.33	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.69

GO:0004674

sp|Q05063|LYOX_CHICK
Protein-lysine 6-oxidase
Search

LOX

0.88	Lysyl oxidase a

0.55	GO:0048251	elastic fiber assembly
0.53	GO:0035904	aorta development
0.53	GO:0030199	collagen fibril organization
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0030324	lung development
0.52	GO:0048514	blood vessel morphogenesis
0.50	GO:0007507	heart development
0.44	GO:0051216	cartilage development
0.43	GO:0007517	muscle organ development
0.42	GO:0022008	neurogenesis

0.77	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
0.72	GO:0005507	copper ion binding
0.42	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0005515	protein binding
0.34	GO:0035091	phosphatidylinositol binding

0.50	GO:0005581	collagen trimer
0.49	GO:0005615	extracellular space
0.49	GO:0005578	proteinaceous extracellular matrix
0.36	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.77

EC:1.4.3

GO:0016641

sp|Q05199|NRG1_CHICK
Pro-neuregulin-1, membrane-bound isoform
Search

NRG1

0.96	Glial growth factor 2

0.77	GO:0009790	embryo development
0.51	GO:0038129	ERBB3 signaling pathway
0.50	GO:0060956	endocardial cell differentiation
0.50	GO:0043497	regulation of protein heterodimerization activity
0.50	GO:0060379	cardiac muscle cell myoblast differentiation
0.50	GO:0048738	cardiac muscle tissue development
0.50	GO:0021840	directional guidance of interneurons involved in migration from the subpallium to the cortex
0.49	GO:0032148	activation of protein kinase B activity
0.49	GO:0021781	glial cell fate commitment
0.49	GO:0045213	neurotransmitter receptor metabolic process

0.73	GO:0005102	receptor binding
0.47	GO:0050839	cell adhesion molecule binding
0.46	GO:0003712	transcription cofactor activity
0.46	GO:0032403	protein complex binding
0.45	GO:0030545	receptor regulator activity
0.39	GO:1990782	protein tyrosine kinase binding
0.32	GO:0030296	protein tyrosine kinase activator activity

0.48	GO:0030673	axolemma
0.47	GO:0031594	neuromuscular junction
0.46	GO:0009897	external side of plasma membrane
0.45	GO:0030425	dendrite
0.45	GO:0044297	cell body
0.44	GO:0005654	nucleoplasm
0.43	GO:0005576	extracellular region
0.41	GO:0005887	integral component of plasma membrane
0.36	GO:0005737	cytoplasm
0.32	GO:0016324	apical plasma membrane

sp|Q05423|FABP7_CHICK
Fatty acid-binding protein, brain
Search

FABP7

0.81	Fatty acid-binding protein, retina

0.53	GO:0060134	prepulse inhibition
0.53	GO:0021846	cell proliferation in forebrain
0.48	GO:0022008	neurogenesis
0.37	GO:0050673	epithelial cell proliferation
0.36	GO:2001245	regulation of phosphatidylcholine biosynthetic process
0.36	GO:0055091	phospholipid homeostasis
0.36	GO:0044539	long-chain fatty acid import
0.36	GO:0046320	regulation of fatty acid oxidation
0.35	GO:0042632	cholesterol homeostasis
0.35	GO:0019433	triglyceride catabolic process

0.72	GO:0008289	lipid binding
0.36	GO:0033293	monocarboxylic acid binding
0.34	GO:0005515	protein binding
0.33	GO:0016787	hydrolase activity

0.50	GO:0043025	neuronal cell body
0.48	GO:0005911	cell-cell junction
0.45	GO:0042995	cell projection
0.40	GO:0071944	cell periphery
0.34	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.34	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016787

sp|Q05437|PRRX1_CHICK
Paired mesoderm homeobox protein 1
Search

PRRX1

0.97	Paired mesoderm homeobox protein 1

0.65	GO:0007275	multicellular organism development
0.57	GO:1904888	cranial skeletal system development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0002053	positive regulation of mesenchymal cell proliferation
0.55	GO:0097150	neuronal stem cell population maintenance
0.55	GO:0045880	positive regulation of smoothened signaling pathway
0.54	GO:0060021	palate development
0.54	GO:0001709	cell fate determination

0.65	GO:0043565	sequence-specific DNA binding
0.56	GO:0071837	HMG box domain binding
0.54	GO:0001105	RNA polymerase II transcription coactivator activity
0.53	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.46	GO:0005829	cytosol
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part

sp|Q05438|BMR1B_CHICK
Bone morphogenetic protein receptor type-1B
Search

BMPR1B

0.60	Receptor protein serine/threonine kinase

0.80	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.72	GO:1902731	negative regulation of chondrocyte proliferation
0.69	GO:0002063	chondrocyte development
0.69	GO:0061036	positive regulation of cartilage development
0.68	GO:0060350	endochondral bone morphogenesis
0.67	GO:0030166	proteoglycan biosynthetic process
0.66	GO:0023014	signal transduction by protein phosphorylation
0.56	GO:0071773	cellular response to BMP stimulus
0.55	GO:0030501	positive regulation of bone mineralization
0.55	GO:0045669	positive regulation of osteoblast differentiation

0.83	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.79	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0046332	SMAD binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0046872	metal ion binding

0.40	GO:0005886	plasma membrane
0.38	GO:0043235	receptor complex
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.35	GO:0089717	spanning component of membrane

0.83

GO:0004675

sp|Q05502|HHEX_CHICK
Hematopoietically-expressed homeobox protein HHEX
Search

HHEX

0.97	Hematopoietically-expressed homeobox protein HHEX

0.61	GO:0061011	hepatic duct development
0.60	GO:0060431	primary lung bud formation
0.60	GO:0061017	hepatoblast differentiation
0.60	GO:0061010	gall bladder development
0.59	GO:0022027	interkinetic nuclear migration
0.59	GO:0070365	hepatocyte differentiation
0.59	GO:0090009	primitive streak formation
0.58	GO:0048853	forebrain morphogenesis
0.58	GO:0030878	thyroid gland development
0.58	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway

0.63	GO:0043565	sequence-specific DNA binding
0.58	GO:0071837	HMG box domain binding
0.58	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.57	GO:0008190	eukaryotic initiation factor 4E binding
0.56	GO:0008301	DNA binding, bending
0.56	GO:0070491	repressing transcription factor binding
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.52	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.49	GO:0032993	protein-DNA complex
0.39	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle

sp|Q05623|MYBPH_CHICK
Myosin-binding protein H
Search

MYBPH

0.97	Myosin-binding protein H

0.85	GO:0071688	striated muscle myosin thick filament assembly
0.83	GO:0045214	sarcomere organization
0.81	GO:0006941	striated muscle contraction
0.72	GO:0007015	actin filament organization
0.51	GO:0007155	cell adhesion
0.43	GO:0006942	regulation of striated muscle contraction

0.86	GO:0097493	structural molecule activity conferring elasticity
0.85	GO:0051371	muscle alpha-actinin binding
0.85	GO:0008307	structural constituent of muscle
0.76	GO:0051015	actin filament binding

0.85	GO:0005859	muscle myosin complex
0.85	GO:0031672	A band
0.81	GO:0030018	Z disc
0.60	GO:0032982	myosin filament

sp|Q05713|CRYAB_CHICK
Alpha-crystallin B chain
Search

CRYAB

0.96	Alpha-crystallin B chain

0.60	GO:1905907	negative regulation of amyloid fibril formation
0.59	GO:0032463	negative regulation of protein homooligomerization
0.58	GO:0060561	apoptotic process involved in morphogenesis
0.58	GO:0071480	cellular response to gamma radiation
0.57	GO:0032387	negative regulation of intracellular transport
0.57	GO:0002088	lens development in camera-type eye
0.56	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.56	GO:0007021	tubulin complex assembly
0.56	GO:0042542	response to hydrogen peroxide
0.55	GO:0001666	response to hypoxia

0.83	GO:0005212	structural constituent of eye lens
0.57	GO:0001540	amyloid-beta binding
0.54	GO:0042803	protein homodimerization activity
0.52	GO:0032403	protein complex binding
0.51	GO:0051082	unfolded protein binding
0.38	GO:0008017	microtubule binding
0.37	GO:0046872	metal ion binding
0.37	GO:0051087	chaperone binding
0.36	GO:0008426	protein kinase C inhibitor activity
0.35	GO:0005080	protein kinase C binding

0.56	GO:0030018	Z disc
0.55	GO:0043209	myelin sheath
0.49	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.45	GO:0005739	mitochondrion
0.43	GO:0005886	plasma membrane
0.41	GO:0097512	cardiac myofibril
0.40	GO:0031430	M band
0.40	GO:0043204	perikaryon
0.40	GO:0043197	dendritic spine

0.33

EC:2.4

GO:0016757

sp|Q05714|CRBB2_CHICK
Beta-crystallin B2
Search

CRYBB2

0.97	Beta B2-crystallin short isoform

0.76	GO:0007601	visual perception
0.52	GO:0043010	camera-type eye development
0.34	GO:0006468	protein phosphorylation
0.33	GO:0050896	response to stimulus
0.33	GO:0023052	signaling
0.33	GO:0007154	cell communication
0.32	GO:0050789	regulation of biological process

0.84	GO:0005212	structural constituent of eye lens
0.49	GO:0042803	protein homodimerization activity
0.37	GO:0047696	beta-adrenergic receptor kinase activity
0.35	GO:0004703	G-protein coupled receptor kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.37

EC:2.7.11.15

GO:0047696

sp|Q05744|CATD_CHICK
Cathepsin D
Search

CTSD

0.90	Cathepsin D preproprotein (Predicted)

0.61	GO:0006508	proteolysis
0.44	GO:0003406	retinal pigment epithelium development
0.43	GO:0006914	autophagy
0.42	GO:0061061	muscle structure development
0.41	GO:0009617	response to bacterium
0.41	GO:0030163	protein catabolic process
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0030574	collagen catabolic process
0.34	GO:0060441	epithelial tube branching involved in lung morphogenesis

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.34	GO:0042277	peptide binding
0.33	GO:0008234	cysteine-type peptidase activity
0.33	GO:0017171	serine hydrolase activity
0.33	GO:0005515	protein binding

0.74	GO:0005764	lysosome
0.38	GO:0042470	melanosome
0.36	GO:0005615	extracellular space
0.35	GO:1903561	extracellular vesicle
0.35	GO:0045121	membrane raft
0.35	GO:1904724	tertiary granule lumen
0.35	GO:0035580	specific granule lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0031012	extracellular matrix
0.34	GO:0005775	vacuolar lumen

0.33

GO:0008234

sp|Q05826|CEBPB_CHICK
CCAAT/enhancer-binding protein beta
Search

CEBPB

0.96	CCAAT enhancer binding protein beta

0.57	GO:0072574	hepatocyte proliferation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0045600	positive regulation of fat cell differentiation
0.56	GO:0010468	regulation of gene expression
0.56	GO:0045669	positive regulation of osteoblast differentiation
0.56	GO:0097421	liver regeneration
0.55	GO:0009617	response to bacterium
0.55	GO:0045444	fat cell differentiation
0.55	GO:0032753	positive regulation of interleukin-4 production

0.61	GO:0003700	DNA binding transcription factor activity
0.57	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.56	GO:0001012	RNA polymerase II regulatory region DNA binding
0.54	GO:0035035	histone acetyltransferase binding
0.53	GO:0042826	histone deacetylase binding
0.52	GO:0001047	core promoter binding
0.52	GO:0019900	kinase binding
0.52	GO:0042803	protein homodimerization activity
0.51	GO:0044389	ubiquitin-like protein ligase binding
0.50	GO:0003682	chromatin binding

0.53	GO:0016363	nuclear matrix
0.51	GO:0005654	nucleoplasm
0.51	GO:0000779	condensed chromosome, centromeric region
0.49	GO:0000790	nuclear chromatin
0.42	GO:0090575	RNA polymerase II transcription factor complex
0.38	GO:0005737	cytoplasm
0.34	GO:0005730	nucleolus
0.32	GO:0005886	plasma membrane

sp|Q05858|FMN_CHICK
Formin
Search

FMN1

0.84

Formin

0.80	GO:0045010	actin nucleation
0.56	GO:0072092	ureteric bud invasion
0.53	GO:0051894	positive regulation of focal adhesion assembly
0.53	GO:0035137	hindlimb morphogenesis
0.53	GO:0035136	forelimb morphogenesis
0.52	GO:0051127	positive regulation of actin nucleation
0.52	GO:0048813	dendrite morphogenesis
0.51	GO:0048705	skeletal system morphogenesis
0.40	GO:0010467	gene expression
0.33	GO:0051758	homologous chromosome movement towards spindle pole involved in homologous chromosome segregation

0.74	GO:0008017	microtubule binding
0.50	GO:0017124	SH3 domain binding
0.35	GO:0003779	actin binding

0.82	GO:0005884	actin filament
0.46	GO:0015630	microtubule cytoskeleton
0.43	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.36	GO:0005912	adherens junction
0.33	GO:0071944	cell periphery
0.33	GO:0005902	microvillus
0.32	GO:0012506	vesicle membrane
0.32	GO:0097708	intracellular vesicle
0.32	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

sp|Q05876|FYN_CHICK
Tyrosine-protein kinase Fyn
Search

FYN

0.64	Tyrosine-protein kinase Fyn

0.74	GO:0018108	peptidyl-tyrosine phosphorylation
0.72	GO:0050852	T cell receptor signaling pathway
0.69	GO:0042110	T cell activation
0.69	GO:1902951	negative regulation of dendritic spine maintenance
0.68	GO:0046777	protein autophosphorylation
0.67	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain
0.67	GO:0001764	neuron migration
0.67	GO:1905430	cellular response to glycine
0.66	GO:0036120	cellular response to platelet-derived growth factor stimulus
0.66	GO:0045087	innate immune response

0.74	GO:0004713	protein tyrosine kinase activity
0.65	GO:0042610	CD8 receptor binding
0.64	GO:0097718	disordered domain specific binding
0.64	GO:0046875	ephrin receptor binding
0.63	GO:0031802	type 5 metabotropic glutamate receptor binding
0.63	GO:0044325	ion channel binding
0.63	GO:0042608	T cell receptor binding
0.61	GO:0070851	growth factor receptor binding
0.61	GO:0051428	peptide hormone receptor binding
0.60	GO:0043548	phosphatidylinositol 3-kinase binding

0.67	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.64	GO:0098857	membrane microdomain
0.62	GO:0014069	postsynaptic density
0.62	GO:0005884	actin filament
0.60	GO:0030425	dendrite
0.58	GO:0005829	cytosol
0.57	GO:0005768	endosome
0.49	GO:0005634	nucleus
0.46	GO:0005739	mitochondrion

0.74	EC:2.7.10	GO:0004713
0.49	KEGG:R04545	GO:0046934

sp|Q05916|HME1_CHICK
Homeobox protein engrailed-1
Search

0.86	Homeobox protein engrailed-1

0.69	GO:0007275	multicellular organism development
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0043524	negative regulation of neuron apoptotic process
0.52	GO:0060322	head development
0.50	GO:0048468	cell development
0.50	GO:1902680	positive regulation of RNA biosynthetic process
0.47	GO:0061743	motor learning
0.46	GO:0042756	drinking behavior

0.64	GO:0043565	sequence-specific DNA binding
0.44	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.42	GO:0001012	RNA polymerase II regulatory region DNA binding
0.41	GO:0003690	double-stranded DNA binding
0.31	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.44	GO:0043233	organelle lumen
0.41	GO:0043232	intracellular non-membrane-bounded organelle
0.40	GO:0044446	intracellular organelle part
0.34	GO:0030175	filopodium
0.34	GO:0030426	growth cone
0.34	GO:0030027	lamellipodium
0.30	GO:0016020	membrane

sp|Q05917|HME2_CHICK
Homeobox protein engrailed-2
Search

0.91	Homeobox protein engrailed-2-A

0.70	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:1901215	negative regulation of neuron death
0.51	GO:0043523	regulation of neuron apoptotic process
0.50	GO:0060322	head development
0.49	GO:0043066	negative regulation of apoptotic process
0.49	GO:0030154	cell differentiation
0.48	GO:0010557	positive regulation of macromolecule biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.40	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.39	GO:0001012	RNA polymerase II regulatory region DNA binding
0.38	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.43	GO:0043233	organelle lumen
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0044446	intracellular organelle part
0.37	GO:0030175	filopodium
0.37	GO:0030426	growth cone
0.37	GO:0030027	lamellipodium
0.30	GO:0016020	membrane

sp|Q06066|YBOX1_CHICK
Nuclease-sensitive element-binding protein 1
Search

YBX1

0.94	TSH receptor suppressor element-binding protein-1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:1903608	protein localization to cytoplasmic stress granule
0.51	GO:1902369	negative regulation of RNA catabolic process
0.50	GO:0051154	negative regulation of striated muscle cell differentiation
0.49	GO:1903312	negative regulation of mRNA metabolic process
0.46	GO:0010558	negative regulation of macromolecule biosynthetic process
0.46	GO:0031327	negative regulation of cellular biosynthetic process
0.46	GO:0006366	transcription by RNA polymerase II

0.54	GO:0003677	DNA binding
0.48	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0003682	chromatin binding
0.45	GO:0051020	GTPase binding
0.42	GO:0003723	RNA binding
0.41	GO:0008190	eukaryotic initiation factor 4E binding
0.36	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.35	GO:0002039	p53 binding
0.34	GO:0008134	transcription factor binding

0.54	GO:0071204	histone pre-mRNA 3'end processing complex
0.51	GO:0070937	CRD-mediated mRNA stability complex
0.49	GO:0005689	U12-type spliceosomal complex
0.49	GO:0010494	cytoplasmic stress granule
0.47	GO:0031965	nuclear membrane
0.43	GO:0005829	cytosol
0.37	GO:0005576	extracellular region
0.35	GO:1990124	messenger ribonucleoprotein complex
0.35	GO:0031982	vesicle
0.34	GO:0043025	neuronal cell body

0.36

EC:5.2.1.8

GO:0003755

sp|Q06637|BFSP1_CHICK
Filensin
Search

BFSP1

0.97	Beaded filament structural protein 1

0.55	GO:0070307	lens fiber cell development
0.52	GO:0048469	cell maturation
0.34	GO:0007010	cytoskeleton organization

0.60	GO:0005198	structural molecule activity
0.34	GO:0005515	protein binding

0.76	GO:0005882	intermediate filament
0.39	GO:0005938	cell cortex
0.35	GO:0005886	plasma membrane

tr|Q06900|Q06900_CHICK
Receptor protein serine/threonine kinase
Search

TGFBR1

0.61	Receptor protein serine/threonine kinase

0.80	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.68	GO:0042118	endothelial cell activation
0.66	GO:0023014	signal transduction by protein phosphorylation
0.66	GO:0060317	cardiac epithelial to mesenchymal transition
0.65	GO:0010717	regulation of epithelial to mesenchymal transition
0.65	GO:0001938	positive regulation of endothelial cell proliferation
0.63	GO:0071560	cellular response to transforming growth factor beta stimulus
0.57	GO:0045893	positive regulation of transcription, DNA-templated
0.55	GO:1905223	epicardium morphogenesis
0.54	GO:0060391	positive regulation of SMAD protein import into nucleus

0.83	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.80	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.67	GO:0050431	transforming growth factor beta binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0005114	type II transforming growth factor beta receptor binding
0.54	GO:0070411	I-SMAD binding
0.54	GO:0008144	drug binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0046872	metal ion binding

0.51	GO:0005923	bicellular tight junction
0.51	GO:0098857	membrane microdomain
0.50	GO:0043235	receptor complex
0.49	GO:0009986	cell surface
0.47	GO:0005768	endosome
0.41	GO:0005886	plasma membrane
0.41	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:1902554	serine/threonine protein kinase complex
0.34	GO:0045177	apical part of cell
0.33	GO:0043234	protein complex

0.83

GO:0004675

sp|Q06A37|CHD7_CHICK
Chromodomain-helicase-DNA-binding protein 7
Search

CHD7

0.91	Chromodomain-helicase-DNA-binding protein 7

0.71	GO:0003226	right ventricular compact myocardium morphogenesis
0.70	GO:0021553	olfactory nerve development
0.68	GO:0060123	regulation of growth hormone secretion
0.68	GO:0036302	atrioventricular canal development
0.68	GO:0048752	semicircular canal morphogenesis
0.68	GO:0007512	adult heart development
0.67	GO:0043584	nose development
0.67	GO:0003222	ventricular trabecula myocardium morphogenesis
0.67	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.67	GO:0030540	female genitalia development

0.66	GO:1990841	promoter-specific chromatin binding
0.61	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.58	GO:0016817	hydrolase activity, acting on acid anhydrides
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005515	protein binding

0.59	GO:0005634	nucleus
0.53	GO:0070013	intracellular organelle lumen
0.48	GO:0043232	intracellular non-membrane-bounded organelle
0.47	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.58

EC:3.6

GO:0016817

tr|Q06AW4|Q06AW4_CHICK
Glucocorticoid-induced leucine zipper protein
Search

TSC22D3

0.39	Glucocorticoid-induced leucine zipper protein

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0070236	negative regulation of activation-induced cell death of T cells
0.46	GO:0048642	negative regulation of skeletal muscle tissue development
0.43	GO:0006970	response to osmotic stress
0.41	GO:1902679	negative regulation of RNA biosynthetic process
0.40	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.40	GO:0009953	dorsal/ventral pattern formation
0.40	GO:0090287	regulation of cellular response to growth factor stimulus

0.61	GO:0003700	DNA binding transcription factor activity
0.47	GO:0043426	MRF binding
0.34	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.42	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm

sp|Q07212|THY1_CHICK
Thy-1 membrane glycoprotein
Search

THY1

0.96	Thy-1 cell surface antigen

0.79	GO:0030334	regulation of cell migration
0.72	GO:0007155	cell adhesion
0.63	GO:0046549	retinal cone cell development
0.62	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity
0.62	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.62	GO:0050860	negative regulation of T cell receptor signaling pathway
0.61	GO:0051894	positive regulation of focal adhesion assembly
0.59	GO:0010977	negative regulation of neuron projection development
0.58	GO:0070570	regulation of neuron projection regeneration
0.58	GO:0001525	angiogenesis

0.84	GO:0005178	integrin binding
0.52	GO:0034235	GPI anchor binding
0.46	GO:0005096	GTPase activator activity
0.45	GO:0019901	protein kinase binding
0.34	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity

0.60	GO:0031362	anchored component of external side of plasma membrane
0.57	GO:0043209	myelin sheath
0.57	GO:0016324	apical plasma membrane
0.56	GO:0030425	dendrite
0.56	GO:0098857	membrane microdomain
0.51	GO:0005783	endoplasmic reticulum
0.45	GO:0030426	growth cone
0.39	GO:0032809	neuronal cell body membrane
0.39	GO:0030673	axolemma
0.37	GO:0005925	focal adhesion

0.34

GO:0036459

tr|Q07420|Q07420_CHICK
Sodium/potassium-transporting ATPase subunit beta
Search

ATP4B

0.80	Potassium-transporting ATPase subunit beta

0.72	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.48	GO:1903288	positive regulation of potassium ion import
0.48	GO:1903275	positive regulation of sodium ion export
0.48	GO:1903276	regulation of sodium ion export across plasma membrane
0.48	GO:0006883	cellular sodium ion homeostasis
0.47	GO:0086009	membrane repolarization
0.47	GO:1901018	positive regulation of potassium ion transmembrane transporter activity
0.46	GO:0030007	cellular potassium ion homeostasis
0.46	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient

0.46	GO:0051117	ATPase binding
0.46	GO:0005391	sodium:potassium-exchanging ATPase activity
0.45	GO:0001671	ATPase activator activity
0.40	GO:0008900	potassium:proton exchanging ATPase activity
0.35	GO:0046982	protein heterodimerization activity

0.84	GO:0005890	sodium:potassium-exchanging ATPase complex
0.45	GO:0016324	apical plasma membrane
0.36	GO:0005737	cytoplasm
0.35	GO:0012505	endomembrane system
0.33	GO:0043231	intracellular membrane-bounded organelle

0.46

GO:0005391

sp|Q07460|IF5A2_CHICK
Eukaryotic translation initiation factor 5A-2
Search

EIF5A2

0.65	Eukaryotic translation initiation factor 5A

0.84	GO:0045905	positive regulation of translational termination
0.84	GO:0045901	positive regulation of translational elongation
0.84	GO:0006452	translational frameshifting
0.60	GO:0006413	translational initiation
0.50	GO:0008284	positive regulation of cell proliferation
0.46	GO:0043065	positive regulation of apoptotic process
0.43	GO:0051028	mRNA transport
0.40	GO:0015031	protein transport
0.38	GO:0071166	ribonucleoprotein complex localization
0.38	GO:0051169	nuclear transport

0.74	GO:0043022	ribosome binding
0.71	GO:0003746	translation elongation factor activity
0.61	GO:0003743	translation initiation factor activity
0.39	GO:0017070	U6 snRNA binding
0.39	GO:0047485	protein N-terminus binding
0.33	GO:0003735	structural constituent of ribosome

0.43	GO:0043231	intracellular membrane-bounded organelle
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.40	GO:0031984	organelle subcompartment
0.39	GO:0031967	organelle envelope
0.38	GO:0098589	membrane region
0.38	GO:0043234	protein complex
0.38	GO:0005737	cytoplasm
0.36	GO:0043025	neuronal cell body
0.36	GO:0070062	extracellular exosome
0.36	GO:0030425	dendrite

sp|Q07494|EPHB1_CHICK
Ephrin type-B receptor 1 (Fragment)
Search

EPHB1

0.93	EPH receptor B1

0.83	GO:0048013	ephrin receptor signaling pathway
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.71	GO:0014719	skeletal muscle satellite cell activation
0.70	GO:0014859	negative regulation of skeletal muscle cell proliferation
0.70	GO:0021631	optic nerve morphogenesis
0.70	GO:1902725	negative regulation of satellite cell differentiation
0.70	GO:0050965	detection of temperature stimulus involved in sensory perception of pain
0.69	GO:0014842	regulation of skeletal muscle satellite cell proliferation
0.69	GO:0060997	dendritic spine morphogenesis
0.68	GO:0021952	central nervous system projection neuron axonogenesis

0.84	GO:0005003	ephrin receptor activity
0.70	GO:0008046	axon guidance receptor activity
0.59	GO:0032403	protein complex binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.68	GO:0032433	filopodium tip
0.66	GO:0005887	integral component of plasma membrane
0.63	GO:0031901	early endosome membrane
0.63	GO:0045121	membrane raft
0.63	GO:0030424	axon
0.54	GO:0005783	endoplasmic reticulum
0.53	GO:0005829	cytosol

sp|Q07496|EPHA4_CHICK
Ephrin type-A receptor 4
Search

EPHA4

0.92	Eph receptor A4, like

0.83	GO:0048013	ephrin receptor signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.75	GO:2001108	positive regulation of Rho guanyl-nucleotide exchange factor activity
0.72	GO:1905247	positive regulation of aspartic-type peptidase activity
0.72	GO:1902959	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
0.72	GO:1905244	regulation of modification of synaptic structure
0.72	GO:0097155	fasciculation of sensory neuron axon
0.71	GO:0097156	fasciculation of motor neuron axon
0.71	GO:1902004	positive regulation of amyloid-beta formation
0.71	GO:0021957	corticospinal tract morphogenesis

0.84	GO:0005003	ephrin receptor activity
0.75	GO:0097161	DH domain binding
0.73	GO:0042731	PH domain binding
0.68	GO:1990782	protein tyrosine kinase binding
0.59	GO:0042802	identical protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.41	GO:0046875	ephrin receptor binding

0.66	GO:0031901	early endosome membrane
0.66	GO:0005887	integral component of plasma membrane
0.63	GO:0030425	dendrite
0.63	GO:0030424	axon
0.41	GO:0043204	perikaryon
0.41	GO:0044309	neuron spine
0.41	GO:0031594	neuromuscular junction
0.41	GO:0043679	axon terminus
0.41	GO:0030175	filopodium
0.41	GO:0030426	growth cone

sp|Q07497|EPHB5_CHICK
Ephrin type-B receptor 5
Search

0.69	EPH receptor B6

0.84	GO:0048013	ephrin receptor signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.60	GO:0022038	corpus callosum development
0.59	GO:0060997	dendritic spine morphogenesis
0.59	GO:0021952	central nervous system projection neuron axonogenesis
0.59	GO:0031290	retinal ganglion cell axon guidance
0.59	GO:0007413	axonal fasciculation
0.58	GO:0001568	blood vessel development
0.58	GO:0051965	positive regulation of synapse assembly
0.57	GO:0060021	palate development

0.85	GO:0005003	ephrin receptor activity
0.60	GO:0008046	axon guidance receptor activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.50	GO:0001540	amyloid-beta binding
0.45	GO:0042802	identical protein binding
0.45	GO:0005102	receptor binding
0.44	GO:0044877	macromolecular complex binding

0.66	GO:0005887	integral component of plasma membrane
0.48	GO:0009986	cell surface
0.48	GO:0043025	neuronal cell body
0.48	GO:0030425	dendrite
0.47	GO:0030424	axon
0.40	GO:0005634	nucleus

sp|Q07498|EPHB3_CHICK
Ephrin type-B receptor 3 (Fragment)
Search

EPHB3

0.86	EPH receptor B3

0.84	GO:0048013	ephrin receptor signaling pathway
0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.60	GO:0034446	substrate adhesion-dependent cell spreading
0.57	GO:0046777	protein autophosphorylation
0.56	GO:0016477	cell migration
0.55	GO:0022407	regulation of cell-cell adhesion
0.55	GO:0022038	corpus callosum development
0.55	GO:0060997	dendritic spine morphogenesis
0.54	GO:0043087	regulation of GTPase activity
0.54	GO:0021952	central nervous system projection neuron axonogenesis

0.85	GO:0005003	ephrin receptor activity
0.55	GO:0008046	axon guidance receptor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.66

GO:0005887

integral component of plasma membrane

sp|Q07598|NLTP_CHICK
Non-specific lipid-transfer protein (Fragment)
Search

SCP2

0.60	Sterol carrier protein 2

0.60	GO:1901373	lipid hydroperoxide transport
0.59	GO:0032379	positive regulation of intracellular lipid transport
0.58	GO:0032380	regulation of intracellular sterol transport
0.57	GO:0032376	positive regulation of cholesterol transport
0.52	GO:0007031	peroxisome organization
0.44	GO:0015918	sterol transport
0.43	GO:0015914	phospholipid transport
0.42	GO:0006694	steroid biosynthetic process
0.39	GO:0032959	inositol trisphosphate biosynthetic process
0.39	GO:0042448	progesterone metabolic process

0.64	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.58	GO:0070538	oleic acid binding
0.58	GO:0036042	long-chain fatty acyl-CoA binding
0.55	GO:0032934	sterol binding
0.53	GO:0043178	alcohol binding
0.49	GO:0005102	receptor binding
0.45	GO:0015248	sterol transporter activity
0.39	GO:0008526	phosphatidylinositol transporter activity
0.36	GO:0005518	collagen binding
0.36	GO:0016758	transferase activity, transferring hexosyl groups

0.52	GO:0005777	peroxisome
0.47	GO:0005654	nucleoplasm
0.44	GO:0005739	mitochondrion
0.43	GO:0043234	protein complex
0.37	GO:0005615	extracellular space
0.37	GO:0031907	microbody lumen
0.36	GO:1903561	extracellular vesicle
0.35	GO:0031012	extracellular matrix
0.34	GO:0031312	extrinsic component of organelle membrane
0.34	GO:0031968	organelle outer membrane

0.64

GO:0016747

sp|Q07816|B2CL1_CHICK
Bcl-2-like protein 1
Search

0.97	Anti-apoptotic regulator Bcl-xL

0.74	GO:0042981	regulation of apoptotic process
0.74	GO:0006915	apoptotic process
0.61	GO:0038034	signal transduction in absence of ligand
0.61	GO:0043069	negative regulation of programmed cell death
0.59	GO:0046902	regulation of mitochondrial membrane permeability
0.59	GO:0051881	regulation of mitochondrial membrane potential
0.59	GO:0070997	neuron death
0.58	GO:0010332	response to gamma radiation
0.58	GO:0001541	ovarian follicle development
0.58	GO:0060154	cellular process regulating host cell cycle in response to virus

0.62	GO:0051434	BH3 domain binding
0.54	GO:0046982	protein heterodimerization activity
0.53	GO:0042802	identical protein binding
0.52	GO:0019901	protein kinase binding
0.45	GO:0051721	protein phosphatase 2A binding
0.43	GO:0002020	protease binding
0.43	GO:0016248	channel inhibitor activity
0.42	GO:0031625	ubiquitin protein ligase binding
0.41	GO:0008134	transcription factor binding
0.40	GO:0022803	passive transmembrane transporter activity

0.57	GO:0097136	Bcl-2 family protein complex
0.55	GO:0005741	mitochondrial outer membrane
0.52	GO:0005813	centrosome
0.51	GO:0005783	endoplasmic reticulum
0.50	GO:0005829	cytosol
0.46	GO:0031965	nuclear membrane
0.43	GO:0043209	myelin sheath
0.42	GO:0046930	pore complex
0.41	GO:0070013	intracellular organelle lumen
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

sp|Q07883|GRB2_CHICK
Growth factor receptor-bound protein 2
Search

GRB2

0.96	Growth factor receptor-bound protein 2

0.82	GO:0007265	Ras protein signal transduction
0.57	GO:0008286	insulin receptor signaling pathway
0.56	GO:0031623	receptor internalization
0.56	GO:0071479	cellular response to ionizing radiation
0.55	GO:0042770	signal transduction in response to DNA damage
0.55	GO:2000379	positive regulation of reactive oxygen species metabolic process
0.55	GO:0060670	branching involved in labyrinthine layer morphogenesis
0.53	GO:0030838	positive regulation of actin filament polymerization
0.52	GO:0043408	regulation of MAPK cascade
0.51	GO:0009967	positive regulation of signal transduction

0.59	GO:0043560	insulin receptor substrate binding
0.59	GO:0005168	neurotrophin TRKA receptor binding
0.58	GO:0005154	epidermal growth factor receptor binding
0.56	GO:0001784	phosphotyrosine residue binding
0.56	GO:0046875	ephrin receptor binding
0.56	GO:0005070	SH3/SH2 adaptor activity
0.55	GO:0019903	protein phosphatase binding
0.53	GO:0017124	SH3 domain binding
0.52	GO:0019901	protein kinase binding
0.50	GO:0042802	identical protein binding

0.59	GO:0070436	Grb2-EGFR complex
0.54	GO:0008180	COP9 signalosome
0.52	GO:0005768	endosome
0.51	GO:0005911	cell-cell junction
0.51	GO:0012506	vesicle membrane
0.50	GO:0005730	nucleolus
0.49	GO:0005654	nucleoplasm
0.45	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.39	GO:0005794	Golgi apparatus
0.36	GO:0070062	extracellular exosome

0.46	EC:2.7.10.2	GO:0004715
0.35	KEGG:R04545	GO:0046934

sp|Q08156|KIT_CHICK
Mast/stem cell growth factor receptor Kit
Search

KIT

0.68	KIT proto-oncogene receptor tyrosine kinase

0.86	GO:0038109	Kit signaling pathway
0.85	GO:0038093	Fc receptor signaling pathway
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.65	GO:0023014	signal transduction by protein phosphorylation
0.62	GO:0097326	melanocyte adhesion
0.62	GO:0002371	dendritic cell cytokine production
0.62	GO:0035556	intracellular signal transduction
0.61	GO:0060374	mast cell differentiation
0.61	GO:0097324	melanocyte migration
0.60	GO:0038162	erythropoietin-mediated signaling pathway

0.85	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity
0.82	GO:0019955	cytokine binding
0.79	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.55	GO:0002020	protease binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.51	GO:0042803	protein homodimerization activity

0.58	GO:0042629	mast cell granule
0.54	GO:0009897	external side of plasma membrane
0.52	GO:0005911	cell-cell junction
0.50	GO:0005615	extracellular space
0.39	GO:0001669	acrosomal vesicle
0.38	GO:0009898	cytoplasmic side of plasma membrane
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.85	EC:2.7.10	GO:0004716
0.35	KEGG:R04545	GO:0046934

sp|Q08200|RL10_CHICK
60S ribosomal protein L10 (Fragment)
Search

RPL10

0.41	Ribosomal protein 10

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.51	GO:1990403	embryonic brain development
0.48	GO:0000027	ribosomal large subunit assembly
0.47	GO:0007283	spermatogenesis
0.45	GO:0006417	regulation of translation
0.42	GO:0007420	brain development
0.38	GO:0043066	negative regulation of apoptotic process

0.64	GO:0003735	structural constituent of ribosome
0.49	GO:0045182	translation regulator activity
0.41	GO:0003723	RNA binding
0.34	GO:0005092	GDP-dissociation inhibitor activity
0.34	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.51	GO:0044445	cytosolic part
0.49	GO:0005783	endoplasmic reticulum
0.46	GO:0005844	polysome
0.43	GO:0044446	intracellular organelle part
0.43	GO:0005634	nucleus
0.35	GO:0043234	protein complex
0.34	GO:0098562	cytoplasmic side of membrane
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle

0.32

GO:0016787

sp|Q08392|GSTA1_CHICK
Glutathione S-transferase
Search

0.43	Glutathione S-transferase class-alpha

0.45	GO:0043390	aflatoxin B1 metabolic process
0.41	GO:0006749	glutathione metabolic process
0.40	GO:0098754	detoxification
0.37	GO:0043651	linoleic acid metabolic process
0.37	GO:0030855	epithelial cell differentiation
0.35	GO:1901687	glutathione derivative biosynthetic process
0.34	GO:0097237	cellular response to toxic substance
0.34	GO:0007568	aging
0.34	GO:0042178	xenobiotic catabolic process
0.34	GO:0031667	response to nutrient levels

0.78	GO:0004364	glutathione transferase activity
0.35	GO:0004602	glutathione peroxidase activity
0.35	GO:0043295	glutathione binding
0.32	GO:0008144	drug binding

0.42	GO:0005829	cytosol
0.37	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.35	GO:0005640	nuclear outer membrane

0.78

GO:0004364

sp|Q08393|GSTA2_CHICK
Glutathione S-transferase
Search

0.43	Glutathione S-transferase

0.43	GO:0043390	aflatoxin B1 metabolic process
0.42	GO:0006749	glutathione metabolic process
0.39	GO:0009636	response to toxic substance
0.37	GO:1901685	glutathione derivative metabolic process
0.37	GO:0070887	cellular response to chemical stimulus
0.37	GO:0043651	linoleic acid metabolic process
0.36	GO:0030855	epithelial cell differentiation
0.36	GO:0010226	response to lithium ion
0.36	GO:0010043	response to zinc ion
0.36	GO:0009410	response to xenobiotic stimulus

0.77	GO:0004364	glutathione transferase activity
0.36	GO:0043295	glutathione binding
0.35	GO:0004602	glutathione peroxidase activity
0.35	GO:0042803	protein homodimerization activity
0.33	GO:0008144	drug binding

0.42	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.33	GO:0005739	mitochondrion

0.77

GO:0004364

sp|Q08705|CTCF_CHICK
Transcriptional repressor CTCF
Search

CTCF

0.86	Transcriptional repressor CTCF

0.46	GO:0040030	regulation of molecular function, epigenetic
0.45	GO:0010216	maintenance of DNA methylation
0.45	GO:0006349	regulation of gene expression by genetic imprinting
0.45	GO:0016584	nucleosome positioning
0.44	GO:0071459	protein localization to chromosome, centromeric region
0.44	GO:0031060	regulation of histone methylation
0.44	GO:0035065	regulation of histone acetylation
0.43	GO:0008285	negative regulation of cell proliferation
0.42	GO:0000122	negative regulation of transcription by RNA polymerase II
0.42	GO:0006366	transcription by RNA polymerase II

0.51	GO:0003676	nucleic acid binding
0.44	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.43	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.42	GO:0003682	chromatin binding
0.37	GO:0005515	protein binding
0.36	GO:0003714	transcription corepressor activity
0.36	GO:0046872	metal ion binding

0.42	GO:0000775	chromosome, centromeric region
0.42	GO:0000793	condensed chromosome
0.41	GO:0005730	nucleolus
0.40	GO:0005654	nucleoplasm

sp|Q08727|HXA2_CHICK
Homeobox protein Hox-A2
Search

HOXA2

0.87	Homeobox protein Hox-A2

0.67	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:0002076	osteoblast development
0.37	GO:0071300	cellular response to retinoic acid
0.37	GO:0045668	negative regulation of osteoblast differentiation
0.37	GO:0001709	cell fate determination
0.37	GO:1904888	cranial skeletal system development

0.65	GO:0043565	sequence-specific DNA binding
0.59	GO:0003700	DNA binding transcription factor activity
0.36	GO:0001012	RNA polymerase II regulatory region DNA binding
0.35	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q08856|MYF5_CHICK
Myogenic factor 5
Search

MYF5

0.93	Myogenic factor

0.81	GO:0007517	muscle organ development
0.61	GO:0014706	striated muscle tissue development
0.59	GO:0001502	cartilage condensation
0.58	GO:0043010	camera-type eye development
0.57	GO:0001756	somitogenesis
0.56	GO:0001952	regulation of cell-matrix adhesion
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0006366	transcription by RNA polymerase II
0.56	GO:0030154	cell differentiation

0.68	GO:0046983	protein dimerization activity
0.59	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.54	GO:0003677	DNA binding
0.49	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.49	GO:0001067	regulatory region nucleic acid binding
0.45	GO:0035257	nuclear hormone receptor binding
0.43	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0003713	transcription coactivator activity
0.42	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.52	GO:0070013	intracellular organelle lumen
0.47	GO:0044446	intracellular organelle part
0.43	GO:0030016	myofibril
0.43	GO:0005667	transcription factor complex
0.41	GO:0005829	cytosol
0.40	GO:0005694	chromosome

sp|Q09108|SCF_CHICK
Kit ligand
Search

KITLG

0.97	KIT ligand form 3

0.71	GO:0007155	cell adhesion
0.61	GO:0010469	regulation of receptor activity
0.58	GO:0033026	negative regulation of mast cell apoptotic process
0.58	GO:0070668	positive regulation of mast cell proliferation
0.58	GO:0035162	embryonic hemopoiesis
0.58	GO:1902035	positive regulation of hematopoietic stem cell proliferation
0.57	GO:0045636	positive regulation of melanocyte differentiation
0.57	GO:0045740	positive regulation of DNA replication
0.57	GO:0008584	male gonad development
0.57	GO:0035234	ectopic germ cell programmed cell death

0.86	GO:0005173	stem cell factor receptor binding
0.62	GO:0008083	growth factor activity
0.52	GO:0005125	cytokine activity
0.35	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.59	GO:0030175	filopodium
0.58	GO:0030027	lamellipodium
0.49	GO:0005615	extracellular space
0.47	GO:0005886	plasma membrane
0.42	GO:0005856	cytoskeleton
0.40	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

sp|Q09121|IF5A1_CHICK
Eukaryotic translation initiation factor 5A-1
Search

EIF5A

0.65	Eukaryotic translation initiation factor 5A

0.84	GO:0045905	positive regulation of translational termination
0.84	GO:0045901	positive regulation of translational elongation
0.84	GO:0006452	translational frameshifting
0.60	GO:0006413	translational initiation
0.48	GO:0008284	positive regulation of cell proliferation
0.46	GO:0043065	positive regulation of apoptotic process
0.42	GO:0051028	mRNA transport
0.40	GO:0006611	protein export from nucleus
0.39	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.38	GO:0006915	apoptotic process

0.74	GO:0043022	ribosome binding
0.71	GO:0003746	translation elongation factor activity
0.60	GO:0003743	translation initiation factor activity
0.39	GO:0017070	U6 snRNA binding
0.39	GO:0047485	protein N-terminus binding
0.34	GO:0003735	structural constituent of ribosome

0.43	GO:0043231	intracellular membrane-bounded organelle
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0031984	organelle subcompartment
0.38	GO:0031967	organelle envelope
0.38	GO:0098589	membrane region
0.38	GO:0005737	cytoplasm
0.38	GO:0043234	protein complex
0.36	GO:0043025	neuronal cell body
0.36	GO:0070062	extracellular exosome
0.36	GO:0030425	dendrite

sp|Q0E4V3|GLL14_CHICK
Gallinacin-14
Search

0.88	Avian beta-defensin 14

0.72	GO:0006952	defense response
0.52	GO:0009617	response to bacterium

0.66

GO:0005576

extracellular region

tr|Q0GFE9|Q0GFE9_CHICK
Thymosin beta 15
Search

0.97	Thymosin beta-b

0.75	GO:0007015	actin filament organization
0.47	GO:1905271	regulation of proton-transporting ATP synthase activity, rotational mechanism
0.47	GO:0042989	sequestering of actin monomers
0.46	GO:0007253	cytoplasmic sequestering of NF-kappaB
0.46	GO:2000483	negative regulation of interleukin-8 secretion
0.46	GO:2001171	positive regulation of ATP biosynthetic process
0.45	GO:1901223	negative regulation of NIK/NF-kappaB signaling
0.45	GO:2001028	positive regulation of endothelial cell chemotaxis
0.45	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
0.44	GO:0043536	positive regulation of blood vessel endothelial cell migration

0.85	GO:0003785	actin monomer binding
0.41	GO:0019899	enzyme binding
0.35	GO:0003727	single-stranded RNA binding
0.34	GO:0004888	transmembrane signaling receptor activity

0.42	GO:0005856	cytoskeleton
0.41	GO:0005829	cytosol
0.41	GO:0005576	extracellular region
0.39	GO:0005634	nucleus
0.35	GO:0031093	platelet alpha granule lumen
0.35	GO:0099512	supramolecular fiber
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q0GGW5|STK11_CHICK
Serine/threonine-protein kinase STK11
Search

STK11

0.96	Serine/threonine-protein kinase 11

0.63	GO:0006468	protein phosphorylation
0.59	GO:0036399	TCR signalosome assembly
0.57	GO:0071493	cellular response to UV-B
0.57	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development
0.57	GO:0043276	anoikis
0.57	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.57	GO:0045059	positive thymic T cell selection
0.56	GO:0048871	multicellular organismal homeostasis
0.56	GO:0097484	dendrite extension
0.56	GO:0042593	glucose homeostasis

0.68	GO:0004674	protein serine/threonine kinase activity
0.56	GO:0030275	LRR domain binding
0.56	GO:0030295	protein kinase activator activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0002039	p53 binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0000287	magnesium ion binding
0.35	GO:0019901	protein kinase binding

0.58	GO:0036398	TCR signalosome
0.48	GO:0005829	cytosol
0.48	GO:0005654	nucleoplasm
0.44	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.68

GO:0004674

tr|Q0JRI2|Q0JRI2_CHICK
CX3CL1 chemokine
Search

0.56	Fractalkine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response

0.84

GO:0008009

chemokine activity

0.66	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

tr|Q0PVE4|Q0PVE4_CHICK
PAR6B
Search

PARD6B

0.97	Partitioning defective 6 like protein beta

0.80	GO:0007163	establishment or maintenance of cell polarity
0.78	GO:0007043	cell-cell junction assembly
0.47	GO:0006461	protein complex assembly
0.40	GO:0048696	regulation of collateral sprouting in absence of injury
0.40	GO:0035844	cloaca development
0.39	GO:0045176	apical protein localization
0.39	GO:0048793	pronephros development
0.39	GO:0021510	spinal cord development
0.39	GO:0001841	neural tube formation
0.39	GO:0035050	embryonic heart tube development

0.34

GO:0005515

protein binding

0.56	GO:0016324	apical plasma membrane
0.52	GO:0005923	bicellular tight junction
0.50	GO:0005938	cell cortex
0.47	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.39	GO:0097610	cell surface furrow
0.38	GO:0032155	cell division site part
0.36	GO:0070062	extracellular exosome
0.35	GO:0043234	protein complex

sp|Q0V8S9|CNTP5_CHICK
Contactin-associated protein-like 5
Search

CNTNAP5

0.91	Contactin associated protein like 5

0.44	GO:2000821	regulation of grooming behavior
0.43	GO:0032225	regulation of synaptic transmission, dopaminergic
0.43	GO:0032228	regulation of synaptic transmission, GABAergic
0.42	GO:0007155	cell adhesion
0.33	GO:0006508	proteolysis

0.44	GO:0005509	calcium ion binding
0.34	GO:0070001	aspartic-type peptidase activity
0.33	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding

0.43	GO:0042734	presynaptic membrane
0.41	GO:0030425	dendrite
0.34	GO:0030054	cell junction
0.30	GO:0031224	intrinsic component of membrane

sp|Q0WYX8|MDGA1_CHICK
MAM domain-containing glycosylphosphatidylinositol anchor protein 1
Search

MDGA1

0.96	MAM domain-containing glycosylphosphatidylinositol anchor protein 1

0.39	GO:0001764	neuron migration
0.38	GO:0007417	central nervous system development
0.37	GO:0060322	head development
0.37	GO:0048513	animal organ development
0.36	GO:0030182	neuron differentiation
0.35	GO:0006501	C-terminal protein lipidation
0.35	GO:0051964	negative regulation of synapse assembly
0.35	GO:0007389	pattern specification process
0.33	GO:0009399	nitrogen fixation
0.32	GO:0055114	oxidation-reduction process

0.34

GO:0016732

oxidoreductase activity, acting on iron-sulfur proteins as donors, dinitrogen as acceptor

0.56	GO:0046658	anchored component of plasma membrane
0.35	GO:0005615	extracellular space
0.34	GO:0045121	membrane raft
0.30	GO:0016021	integral component of membrane

0.34

EC:1.18.6

GO:0016732

sp|Q0ZM14|PCD15_CHICK
Protocadherin-15
Search

PCDH15

0.92	Protocadherin-15

0.81	GO:0048839	inner ear development
0.81	GO:0007605	sensory perception of sound
0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.50	GO:0050973	detection of mechanical stimulus involved in equilibrioception
0.48	GO:0060013	righting reflex
0.47	GO:0050953	sensory perception of light stimulus
0.47	GO:0001964	startle response
0.47	GO:0007628	adult walking behavior
0.47	GO:0035315	hair cell differentiation
0.46	GO:0060563	neuroepithelial cell differentiation

0.70	GO:0005509	calcium ion binding
0.34	GO:0047485	protein N-terminus binding
0.34	GO:0032403	protein complex binding

0.84	GO:0032420	stereocilium
0.56	GO:0005886	plasma membrane
0.47	GO:0001750	photoreceptor outer segment
0.36	GO:0070062	extracellular exosome
0.36	GO:0005737	cytoplasm
0.36	GO:0045202	synapse
0.30	GO:0031224	intrinsic component of membrane

sp|Q10751|ACE_CHICK
Angiotensin-converting enzyme (Fragment)
Search

0.10	Angiotensin-converting enzyme (Fragment)

0.61	GO:0006508	proteolysis
0.30	GO:0048869	cellular developmental process
0.30	GO:0009790	embryo development
0.30	GO:0042592	homeostatic process
0.30	GO:0008283	cell proliferation
0.30	GO:0030097	hemopoiesis

0.84	GO:0008241	peptidyl-dipeptidase activity
0.72	GO:0004180	carboxypeptidase activity
0.67	GO:0008237	metallopeptidase activity
0.54	GO:0046872	metal ion binding
0.30	GO:0004177	aminopeptidase activity

0.30

GO:0031224

intrinsic component of membrane

0.84

EC:3.4.15

GO:0008241

sp|Q11200|SIA4A_CHICK
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
Search

ST3GAL1

0.94	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2

0.83	GO:0097503	sialylation
0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.60	GO:0036211	protein modification process
0.56	GO:0044267	cellular protein metabolic process
0.50	GO:0009311	oligosaccharide metabolic process
0.47	GO:0030259	lipid glycosylation
0.45	GO:0009247	glycolipid biosynthetic process
0.43	GO:0016051	carbohydrate biosynthetic process
0.43	GO:0016310	phosphorylation

0.84

GO:0008373

sialyltransferase activity

0.70	GO:0005794	Golgi apparatus
0.45	GO:0098588	bounding membrane of organelle
0.44	GO:0031984	organelle subcompartment
0.39	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:2.4.99

GO:0008373

tr|Q155F6|Q155F6_CHICK
Tumor necrosis factor-inducible protein 6
Search

TNFAIP6

0.97	Tumor necrosis factor alpha-induced protein 6

0.71	GO:0007155	cell adhesion
0.58	GO:0050728	negative regulation of inflammatory response
0.41	GO:0030728	ovulation
0.40	GO:0030335	positive regulation of cell migration
0.39	GO:0016525	negative regulation of angiogenesis
0.38	GO:0007267	cell-cell signaling
0.38	GO:0042742	defense response to bacterium
0.37	GO:0016192	vesicle-mediated transport
0.37	GO:0098657	import into cell
0.35	GO:0002283	neutrophil activation involved in immune response

0.84	GO:0005540	hyaluronic acid binding
0.42	GO:0005509	calcium ion binding
0.40	GO:0005041	low-density lipoprotein receptor activity
0.40	GO:0030169	low-density lipoprotein particle binding
0.38	GO:0005044	scavenger receptor activity
0.34	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0004222	metalloendopeptidase activity
0.32	GO:0015035	protein disulfide oxidoreductase activity
0.32	GO:0031419	cobalamin binding

0.39	GO:0005615	extracellular space
0.36	GO:0005887	integral component of plasma membrane
0.36	GO:1904724	tertiary granule lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.34	GO:0030139	endocytic vesicle
0.33	GO:0005903	brush border
0.33	GO:0098805	whole membrane
0.33	GO:0016324	apical plasma membrane
0.33	GO:1903561	extracellular vesicle
0.33	GO:0030659	cytoplasmic vesicle membrane

0.32

GO:0004222

tr|Q156C7|Q156C7_CHICK
5'-AMP-activated protein kinase beta-2 non-catalytic subunit transcript variant 2
Search

PRKAB2

0.97	5'-AMP-activated protein kinase beta-2 non-catalytic subunit transcript variant 2

0.56	GO:0016310	phosphorylation
0.51	GO:0035878	nail development
0.46	GO:0036211	protein modification process
0.44	GO:0010628	positive regulation of gene expression
0.44	GO:0044267	cellular protein metabolic process
0.37	GO:0006633	fatty acid biosynthetic process
0.36	GO:1901796	regulation of signal transduction by p53 class mediator
0.36	GO:0016241	regulation of macroautophagy
0.36	GO:0007050	cell cycle arrest
0.36	GO:0006853	carnitine shuttle

0.59	GO:0016301	kinase activity
0.49	GO:0042802	identical protein binding
0.47	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.45	GO:0140096	catalytic activity, acting on a protein
0.45	GO:0060089	molecular transducer activity
0.35	GO:0019901	protein kinase binding

0.54	GO:0031588	nucleotide-activated protein kinase complex
0.42	GO:0005634	nucleus
0.36	GO:0043233	organelle lumen
0.35	GO:0005829	cytosol
0.35	GO:0005952	cAMP-dependent protein kinase complex
0.35	GO:0044446	intracellular organelle part
0.34	GO:0016324	apical plasma membrane
0.30	GO:0016021	integral component of membrane

0.47

GO:0016773

tr|Q197G3|Q197G3_CHICK
Fibroblast growth factor
Search

FGF16

0.62	Fibroblast growth factor

0.84	GO:0008543	fibroblast growth factor receptor signaling pathway
0.75	GO:0010469	regulation of receptor activity
0.59	GO:0090287	regulation of cellular response to growth factor stimulus
0.57	GO:2001028	positive regulation of endothelial cell chemotaxis
0.53	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.53	GO:0035107	appendage morphogenesis
0.52	GO:0060484	lung-associated mesenchyme development
0.52	GO:0032927	positive regulation of activin receptor signaling pathway
0.52	GO:0048505	regulation of timing of cell differentiation
0.52	GO:0008584	male gonad development

0.85	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.39	GO:0008201	heparin binding
0.37	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0004713	protein tyrosine kinase activity

0.66	GO:0005576	extracellular region
0.37	GO:0031982	vesicle
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.37	EC:2.7.1.153	GO:0046934
0.37	KEGG:R04545	GO:0046934

tr|Q19NX1|Q19NX1_CHICK
Dexamethasone-induced ras-related 1
Search

RASD1

0.97	Activator of G-protein signaling 1

0.61	GO:0007165	signal transduction
0.39	GO:0001963	synaptic transmission, dopaminergic
0.38	GO:0007626	locomotory behavior
0.37	GO:0051172	negative regulation of nitrogen compound metabolic process
0.37	GO:0031324	negative regulation of cellular metabolic process
0.36	GO:0010558	negative regulation of macromolecule biosynthetic process
0.36	GO:0010629	negative regulation of gene expression
0.35	GO:0080090	regulation of primary metabolic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0043949	regulation of cAMP-mediated signaling

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0031681	G-protein beta-subunit binding
0.34	GO:0043548	phosphatidylinositol 3-kinase binding
0.34	GO:0031624	ubiquitin conjugating enzyme binding

0.54	GO:0016529	sarcoplasmic reticulum
0.38	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005634	nucleus
0.34	GO:0005886	plasma membrane

sp|Q1G7G9|TALD3_CHICK
TALPID3 protein
Search

0.84	GO:0007224	smoothened signaling pathway
0.54	GO:0060271	cilium assembly
0.53	GO:0070201	regulation of establishment of protein localization
0.39	GO:0051642	centrosome localization

0.33

GO:0005515

protein binding

0.56	GO:0036064	ciliary basal body
0.53	GO:0005813	centrosome
0.47	GO:0005814	centriole
0.37	GO:0001917	photoreceptor inner segment
0.30	GO:0031224	intrinsic component of membrane

tr|Q1G7H4|Q1G7H4_CHICK
DAPPER1
Search

DACT1

0.97	Dishevelled binding antagonist of beta catenin 1

0.86	GO:1904863	regulation of beta-catenin-TCF complex assembly
0.85	GO:0035413	positive regulation of catenin import into nucleus
0.83	GO:0046329	negative regulation of JNK cascade
0.80	GO:0032092	positive regulation of protein binding
0.80	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.80	GO:0032091	negative regulation of protein binding
0.80	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.79	GO:0030177	positive regulation of Wnt signaling pathway
0.78	GO:0021915	neural tube development
0.76	GO:0031333	negative regulation of protein complex assembly

0.83	GO:0051018	protein kinase A binding
0.81	GO:0008013	beta-catenin binding
0.80	GO:0042826	histone deacetylase binding
0.79	GO:0001085	RNA polymerase II transcription factor binding
0.70	GO:0070097	delta-catenin binding
0.67	GO:0005080	protein kinase C binding
0.38	GO:0042802	identical protein binding
0.32	GO:0004871	signal transducer activity

0.84	GO:0030877	beta-catenin destruction complex
0.67	GO:0005654	nucleoplasm
0.41	GO:0045202	synapse
0.40	GO:0030054	cell junction
0.37	GO:0005829	cytosol
0.33	GO:1905360	GTPase complex
0.33	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.32	GO:0098797	plasma membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q1HGK7|KTNA1_CHICK
Katanin p60 ATPase-containing subunit A1
Search

KATNA1

0.79	Katanin p60 ATPase-containing subunit A1

0.84	GO:0051013	microtubule severing
0.64	GO:0051301	cell division
0.64	GO:0007049	cell cycle
0.49	GO:0007283	spermatogenesis
0.43	GO:0031122	cytoplasmic microtubule organization
0.42	GO:0048675	axon extension
0.42	GO:0035329	hippo signaling
0.37	GO:0036211	protein modification process
0.36	GO:0044267	cellular protein metabolic process
0.36	GO:0001764	neuron migration

0.85	GO:0008568	microtubule-severing ATPase activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0046982	protein heterodimerization activity
0.39	GO:0042802	identical protein binding
0.39	GO:0004674	protein serine/threonine kinase activity
0.36	GO:0070840	dynein complex binding
0.35	GO:0004842	ubiquitin-protein transferase activity

0.76	GO:0000922	spindle pole
0.74	GO:0005813	centrosome
0.70	GO:0005874	microtubule
0.65	GO:0030496	midbody
0.54	GO:0072686	mitotic spindle
0.48	GO:0005737	cytoplasm
0.40	GO:0005634	nucleus
0.37	GO:0031463	Cul3-RING ubiquitin ligase complex
0.36	GO:0005811	lipid droplet
0.36	GO:0030424	axon

0.85	EC:3.6.4.3	GO:0008568
0.35	KEGG:R03876	GO:0004842

sp|Q1KME6|RAB6A_CHICK
Ras-related protein Rab-6A
Search

RAB6A

0.89	Ras-related protein Rab-6A isoform A

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.38

GO:0005794

Golgi apparatus

tr|Q1KMR2|Q1KMR2_CHICK
Prostaglandin E receptor 3
Search

PTGER3

0.97	Prostaglandin E receptor 3

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.51	GO:0060455	negative regulation of gastric acid secretion
0.51	GO:0014827	intestine smooth muscle contraction
0.39	GO:0031622	positive regulation of fever generation
0.39	GO:0032496	response to lipopolysaccharide
0.37	GO:0035810	positive regulation of urine volume
0.37	GO:0001660	fever generation
0.37	GO:0015701	bicarbonate transport
0.36	GO:0032355	response to estradiol
0.36	GO:0007204	positive regulation of cytosolic calcium ion concentration

0.85	GO:0004955	prostaglandin receptor activity
0.51	GO:0004960	thromboxane receptor activity
0.34	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.36	GO:0005886	plasma membrane
0.36	GO:0005635	nuclear envelope
0.36	GO:1990769	proximal neuron projection
0.35	GO:0005903	brush border
0.34	GO:0043025	neuronal cell body
0.34	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0009986	cell surface
0.33	GO:0005576	extracellular region
0.33	GO:0031090	organelle membrane
0.32	GO:0005737	cytoplasm

tr|Q1KNA8|Q1KNA8_CHICK
GHRH/PACAP-like
Search

GHRH

0.83	Growth hormone releasing hormone

0.76	GO:0010469	regulation of receptor activity
0.59	GO:0007218	neuropeptide signaling pathway
0.45	GO:0070459	prolactin secretion
0.44	GO:0048255	mRNA stabilization
0.39	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.39	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.33	GO:0019933	cAMP-mediated signaling
0.33	GO:0045732	positive regulation of protein catabolic process
0.33	GO:0032880	regulation of protein localization

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.31	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|Q1PRL4|LIN41_CHICK
E3 ubiquitin-protein ligase TRIM71
Search

TRIM71

0.88	Tripartite motif-containing protein 71

0.72	GO:0061158	3'-UTR-mediated mRNA destabilization
0.70	GO:0035196	production of miRNAs involved in gene silencing by miRNA
0.67	GO:0010586	miRNA metabolic process
0.67	GO:2000637	positive regulation of gene silencing by miRNA
0.65	GO:0035278	miRNA mediated inhibition of translation
0.65	GO:0072089	stem cell proliferation
0.65	GO:0051865	protein autoubiquitination
0.65	GO:2000177	regulation of neural precursor cell proliferation
0.65	GO:0001843	neural tube closure
0.64	GO:0008543	fibroblast growth factor receptor signaling pathway

0.71	GO:0035198	miRNA binding
0.70	GO:0030371	translation repressor activity
0.63	GO:0008270	zinc ion binding
0.59	GO:0061630	ubiquitin protein ligase activity

0.66

GO:0000932

P-body

sp|Q1T763|CENPR_CHICK
Centromere protein R
Search

ITGB3BP

0.97	Centromere protein R

0.86	GO:0034080	CENP-A containing nucleosome assembly
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.40	GO:0006351	transcription, DNA-templated
0.38	GO:0007229	integrin-mediated signaling pathway
0.37	GO:0051301	cell division
0.37	GO:0007049	cell cycle
0.35	GO:0043065	positive regulation of apoptotic process
0.35	GO:0006915	apoptotic process

0.35	GO:0008022	protein C-terminus binding
0.33	GO:0004871	signal transducer activity

0.48	GO:0000777	condensed chromosome kinetochore
0.44	GO:0005634	nucleus
0.42	GO:0031974	membrane-enclosed lumen
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q1T764|CENPQ_CHICK
Centromere protein Q
Search

CENPQ

0.96	Centromere protein Q

0.82	GO:1905342	positive regulation of protein localization to kinetochore
0.77	GO:0051310	metaphase plate congression

0.58	GO:0015629	actin cytoskeleton
0.57	GO:0000775	chromosome, centromeric region
0.57	GO:0005634	nucleus
0.54	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q1T765|CENPN_CHICK
Centromere protein N
Search

CENPN

0.97	Centromere protein N-B

0.83	GO:0034508	centromere complex assembly
0.73	GO:0007059	chromosome segregation
0.36	GO:0031055	chromatin remodeling at centromere
0.36	GO:0061641	CENP-A containing chromatin organization
0.35	GO:0006336	DNA replication-independent nucleosome assembly
0.35	GO:0043486	histone exchange
0.34	GO:0022402	cell cycle process

0.33	GO:0017056	structural constituent of nuclear pore
0.32	GO:0003676	nucleic acid binding

0.47	GO:0005634	nucleus
0.42	GO:0000775	chromosome, centromeric region
0.38	GO:0000793	condensed chromosome
0.35	GO:0043234	protein complex
0.34	GO:0005829	cytosol
0.34	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

tr|Q1T766|Q1T766_CHICK
Nsl1 protein
Search

NSL1

0.94	Kinetochore-associated protein NSL1

0.79	GO:0000070	mitotic sister chromatid segregation
0.37	GO:0007062	sister chromatid cohesion
0.36	GO:0051301	cell division

0.35

GO:0005515

protein binding

0.78	GO:0000776	kinetochore
0.43	GO:0016607	nuclear speck
0.43	GO:0000779	condensed chromosome, centromeric region
0.36	GO:0005829	cytosol

tr|Q1T768|Q1T768_CHICK
Dsn1 protein
Search

DSN1

0.97	kinetochore-associated protein DSN1 homolog

0.73	GO:0007059	chromosome segregation
0.67	GO:0051301	cell division
0.52	GO:0007135	meiosis II
0.50	GO:0070192	chromosome organization involved in meiotic cell cycle
0.49	GO:0140014	mitotic nuclear division
0.38	GO:0043312	neutrophil degranulation

0.34

GO:0005515

protein binding

0.85	GO:0000444	MIS12/MIND type complex
0.67	GO:0001650	fibrillar center
0.63	GO:0016604	nuclear body
0.57	GO:0005829	cytosol
0.54	GO:0000941	condensed nuclear chromosome inner kinetochore
0.49	GO:0000922	spindle pole
0.38	GO:0035578	azurophil granule lumen
0.36	GO:0000813	ESCRT I complex
0.35	GO:0005576	extracellular region

sp|Q1T769|MIS12_CHICK
Protein MIS12 homolog
Search

MIS12

0.97	MIS12 kinetochore complex component

0.75	GO:0000278	mitotic cell cycle
0.70	GO:0051382	kinetochore assembly
0.69	GO:0051310	metaphase plate congression
0.67	GO:0008608	attachment of spindle microtubules to kinetochore
0.64	GO:0000819	sister chromatid segregation
0.64	GO:0000280	nuclear division
0.53	GO:0034501	protein localization to kinetochore

0.77	GO:0000775	chromosome, centromeric region
0.64	GO:0000793	condensed chromosome
0.61	GO:0005634	nucleus
0.52	GO:0043234	protein complex
0.46	GO:0031974	membrane-enclosed lumen

sp|Q1T7B7|CENPP_CHICK
Centromere protein P
Search

CENPP

0.96	Centromere protein P

0.86

GO:0034080

CENP-A containing nucleosome assembly

0.77	GO:0000775	chromosome, centromeric region
0.47	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

sp|Q1T7B8|CENPO_CHICK
Centromere protein O
Search

CENPO

0.97	Centromere protein O

0.83	GO:0034508	centromere complex assembly
0.36	GO:0031055	chromatin remodeling at centromere
0.36	GO:0061641	CENP-A containing chromatin organization
0.35	GO:0006336	DNA replication-independent nucleosome assembly
0.35	GO:0043486	histone exchange
0.35	GO:0007062	sister chromatid cohesion

0.33

GO:0005515

protein binding

0.78	GO:0000776	kinetochore
0.38	GO:0000779	condensed chromosome, centromeric region
0.38	GO:0005634	nucleus
0.34	GO:0005829	cytosol
0.34	GO:0043233	organelle lumen

sp|Q1T7B9|CENPM_CHICK
Centromere protein M
Search

CENPM

0.97	Proliferation associated nuclear element 1

0.41	GO:0034080	CENP-A containing nucleosome assembly
0.39	GO:0007062	sister chromatid cohesion

0.67	GO:0005829	cytosol
0.50	GO:0000775	chromosome, centromeric region
0.44	GO:0000793	condensed chromosome
0.43	GO:0005634	nucleus
0.39	GO:0043234	protein complex
0.37	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q1T7C0|CENPL_CHICK
Centromere protein L
Search

CENPL

0.97	Centromere protein L

0.53	GO:0034080	CENP-A containing nucleosome assembly
0.49	GO:0007062	sister chromatid cohesion

0.43

GO:0005515

protein binding

0.77	GO:0000775	chromosome, centromeric region
0.61	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.44	GO:0031974	membrane-enclosed lumen

sp|Q1T7C1|CENPK_CHICK
Centromere protein K
Search

CENPK

0.97	Centromere protein K

0.37	GO:0034080	CENP-A containing nucleosome assembly
0.36	GO:0007062	sister chromatid cohesion
0.35	GO:0045944	positive regulation of transcription by RNA polymerase II

0.35

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.42	GO:0000777	condensed chromosome kinetochore
0.34	GO:0005829	cytosol
0.34	GO:0031974	membrane-enclosed lumen
0.30	GO:0016020	membrane

sp|Q1XA76|ASIC1_CHICK
Acid-sensing ion channel 1
Search

ASIC1

0.87	Amiloride-sensitive sodium channel subunit beta

0.77	GO:0035725	sodium ion transmembrane transport
0.55	GO:0050915	sensory perception of sour taste
0.54	GO:0046929	negative regulation of neurotransmitter secretion
0.53	GO:0071467	cellular response to pH
0.52	GO:0010447	response to acidic pH
0.52	GO:0008306	associative learning
0.52	GO:0007613	memory
0.49	GO:0042391	regulation of membrane potential
0.49	GO:0070588	calcium ion transmembrane transport
0.43	GO:0070207	protein homotrimerization

0.84	GO:0015280	ligand-gated sodium channel activity
0.36	GO:0005515	protein binding
0.34	GO:0005248	voltage-gated sodium channel activity
0.34	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity
0.33	GO:0051287	NAD binding

0.48	GO:0045202	synapse
0.48	GO:0005887	integral component of plasma membrane
0.47	GO:0005794	Golgi apparatus
0.37	GO:0009986	cell surface
0.35	GO:0097458	neuron part
0.34	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0016514	SWI/SNF complex
0.34	GO:0009331	glycerol-3-phosphate dehydrogenase complex

0.34	EC:1.1.1.8 EC:1.1.1.94	GO:0004367
0.34	KEGG:R00842	GO:0004367

tr|Q1XDY5|Q1XDY5_CHICK
Cytotoxic T-lymphocyte-associated protein 4
Search

CTLA4

0.97	Cytotoxic T-lymphocyte-associated protein 4

0.74	GO:0006955	immune response
0.62	GO:0045590	negative regulation of regulatory T cell differentiation
0.60	GO:0030889	negative regulation of B cell proliferation
0.58	GO:0050853	B cell receptor signaling pathway
0.54	GO:0043065	positive regulation of apoptotic process
0.47	GO:0006974	cellular response to DNA damage stimulus
0.40	GO:0042130	negative regulation of T cell proliferation
0.37	GO:0050777	negative regulation of immune response
0.35	GO:0031295	T cell costimulation

0.35	GO:0005515	protein binding
0.34	GO:0004872	receptor activity

0.57	GO:0045334	clathrin-coated endocytic vesicle
0.56	GO:0009897	external side of plasma membrane
0.56	GO:0098636	protein complex involved in cell adhesion
0.55	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005794	Golgi apparatus
0.49	GO:0005887	integral component of plasma membrane

sp|Q1XI86|IMPG2_CHICK
Interphotoreceptor matrix proteoglycan 2
Search

IMPG2

0.83	Interphotoreceptor matrix proteoglycan 2

0.76	GO:0007601	visual perception
0.34	GO:0006508	proteolysis

0.82	GO:0005540	hyaluronic acid binding
0.79	GO:0005201	extracellular matrix structural constituent
0.54	GO:0008201	heparin binding
0.36	GO:0008234	cysteine-type peptidase activity

0.85	GO:0033165	interphotoreceptor matrix
0.51	GO:0043235	receptor complex
0.30	GO:0044425	membrane part

0.36

GO:0008234

sp|Q25BN1|DICER_CHICK
Endoribonuclease Dicer
Search

DICER1

0.94	LOW QUALITY PROTEIN: endoribonuclease Dicer

0.78	GO:0031047	gene silencing by RNA
0.70	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.64	GO:0036404	conversion of ds siRNA to ss siRNA
0.59	GO:0016441	posttranscriptional gene silencing
0.56	GO:0017148	negative regulation of translation
0.54	GO:0022618	ribonucleoprotein complex assembly
0.50	GO:0006309	apoptotic DNA fragmentation
0.49	GO:0034470	ncRNA processing
0.41	GO:0014040	positive regulation of Schwann cell differentiation
0.41	GO:0032290	peripheral nervous system myelin formation

0.77	GO:0004525	ribonuclease III activity
0.61	GO:0035197	siRNA binding
0.58	GO:0070883	pre-miRNA binding
0.54	GO:0019904	protein domain specific binding
0.54	GO:0003725	double-stranded RNA binding
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0008144	drug binding
0.50	GO:0004530	deoxyribonuclease I activity

0.63	GO:0070578	RISC-loading complex
0.62	GO:0035068	micro-ribonucleoprotein complex
0.57	GO:0070062	extracellular exosome
0.49	GO:0016442	RISC complex
0.41	GO:0005634	nucleus
0.39	GO:0030426	growth cone
0.39	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.38	GO:0030425	dendrite
0.38	GO:0030424	axon
0.38	GO:0034507	chromosome, centromeric outer repeat region

0.77

EC:3.1.26.3

GO:0004525

sp|Q25C36|OLFL3_CHICK
Olfactomedin-like protein 3
Search

OLFML3

0.95	Olfactomedin like 3

0.66	GO:0007275	multicellular organism development
0.49	GO:0072577	endothelial cell apoptotic process
0.48	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway
0.48	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.47	GO:0031128	developmental induction
0.47	GO:0034333	adherens junction assembly
0.47	GO:0097191	extrinsic apoptotic signaling pathway
0.46	GO:0007224	smoothened signaling pathway
0.45	GO:0006086	acetyl-CoA biosynthetic process from pyruvate
0.45	GO:0008284	positive regulation of cell proliferation

0.47	GO:0019164	pyruvate synthase activity
0.44	GO:0042802	identical protein binding
0.40	GO:0004672	protein kinase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0004930	G-protein coupled receptor activity
0.36	GO:0030246	carbohydrate binding

0.61	GO:0005576	extracellular region
0.48	GO:0031982	vesicle
0.47	GO:0016605	PML body
0.45	GO:0016607	nuclear speck
0.45	GO:0005813	centrosome
0.42	GO:0005829	cytosol
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.47	EC:1.2.7.1	GO:0019164
0.47	KEGG:R01196	GO:0019164

tr|Q25QX5|Q25QX5_CHICK
BASH/BLNK N-terminal associated protein 1
Search

0.97	BASH/BLNK N-terminal associated protein 1

0.33	GO:0006412	translation
0.32	GO:0006629	lipid metabolic process

0.34	GO:0003735	structural constituent of ribosome
0.33	GO:0030729	acetoacetate-CoA ligase activity

0.61	GO:0005739	mitochondrion
0.36	GO:0031968	organelle outer membrane
0.33	GO:0005840	ribosome
0.30	GO:0044425	membrane part

0.33	EC:6.2.1.16	GO:0030729
0.33	KEGG:R01357	GO:0030729

tr|Q27IP4|Q27IP4_CHICK
5'AMP-activated protein kinase beta-1 non-catalytic subunit
Search

PRKAB1

0.97	5'AMP-activated protein kinase beta-1 non-catalytic subunit

0.60	GO:0035878	nail development
0.56	GO:0016310	phosphorylation
0.50	GO:0010628	positive regulation of gene expression
0.46	GO:0036211	protein modification process
0.44	GO:0044267	cellular protein metabolic process
0.40	GO:0051291	protein heterooligomerization
0.38	GO:0006633	fatty acid biosynthetic process
0.37	GO:0050790	regulation of catalytic activity
0.35	GO:1901796	regulation of signal transduction by p53 class mediator
0.35	GO:0016241	regulation of macroautophagy

0.59	GO:0016301	kinase activity
0.47	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.45	GO:0140096	catalytic activity, acting on a protein
0.41	GO:0042802	identical protein binding
0.41	GO:0060089	molecular transducer activity
0.39	GO:0019901	protein kinase binding
0.34	GO:0004623	phospholipase A2 activity
0.33	GO:0005509	calcium ion binding

0.47	GO:0031588	nucleotide-activated protein kinase complex
0.45	GO:0005634	nucleus
0.35	GO:0005829	cytosol
0.34	GO:0043233	organelle lumen
0.34	GO:0005952	cAMP-dependent protein kinase complex
0.34	GO:0016324	apical plasma membrane
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.47

GO:0016773

tr|Q29ZM6|Q29ZM6_CHICK
Ladybird-like homeobox 3
Search

LBX1

0.97	Ladybird homeobox 1 transcription factor

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0021519	spinal cord association neuron specification
0.53	GO:0048664	neuron fate determination
0.51	GO:0021522	spinal cord motor neuron differentiation
0.50	GO:0001947	heart looping
0.50	GO:0045665	negative regulation of neuron differentiation
0.48	GO:0008285	negative regulation of cell proliferation
0.46	GO:0061061	muscle structure development

0.64	GO:0043565	sequence-specific DNA binding
0.42	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.30	GO:0016021	integral component of membrane

tr|Q2AB81|Q2AB81_CHICK
Taste receptor type 2
Search

0.69	Taste receptor type 2

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.41	GO:0071409	cellular response to cycloheximide
0.41	GO:0072743	cellular response to erythromycin
0.40	GO:1904560	response to diphenidol
0.40	GO:0072747	cellular response to chloramphenicol
0.40	GO:1902656	calcium ion import into cytosol
0.39	GO:0050907	detection of chemical stimulus involved in sensory perception

0.72	GO:0004930	G-protein coupled receptor activity
0.42	GO:0033038	bitter taste receptor activity

0.30	GO:0016020	membrane
0.30	GO:0005623	cell

tr|Q2AB82|Q2AB82_CHICK
Taste receptor type 2
Search

TAS2R2

0.49	Taste receptor type 2

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.54	GO:1904560	response to diphenidol
0.53	GO:0072747	cellular response to chloramphenicol
0.52	GO:0080184	response to phenylpropanoid
0.51	GO:0071313	cellular response to caffeine
0.49	GO:1902656	calcium ion import into cytosol
0.49	GO:0050907	detection of chemical stimulus involved in sensory perception
0.48	GO:0097306	cellular response to alcohol

0.72	GO:0004930	G-protein coupled receptor activity
0.54	GO:0033038	bitter taste receptor activity

0.30	GO:0016020	membrane
0.30	GO:0005623	cell

tr|Q2AB83|Q2AB83_CHICK
Taste receptor type 2
Search

0.52	Taste receptor type 2

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0050907	detection of chemical stimulus involved in sensory perception
0.42	GO:1904558	response to dextromethorphan
0.42	GO:1904560	response to diphenidol
0.42	GO:0072747	cellular response to chloramphenicol
0.41	GO:0080184	response to phenylpropanoid
0.41	GO:1902350	cellular response to chloroquine
0.41	GO:0071316	cellular response to nicotine
0.40	GO:1902656	calcium ion import into cytosol

0.72	GO:0004930	G-protein coupled receptor activity
0.58	GO:0033038	bitter taste receptor activity

0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q2EJU6|Q2EJU6_CHICK
Pentaxin
Search

0.85

Pentaxin

0.43	GO:0045596	negative regulation of cell differentiation
0.43	GO:1903016	negative regulation of exo-alpha-sialidase activity
0.43	GO:0052403	negative regulation by host of symbiont catalytic activity
0.43	GO:0044867	modulation by host of viral catalytic activity
0.43	GO:0044870	modulation by host of viral glycoprotein metabolic process
0.42	GO:0044793	negative regulation by host of viral process
0.42	GO:0051239	regulation of multicellular organismal process
0.42	GO:0046597	negative regulation of viral entry into host cell
0.42	GO:1903019	negative regulation of glycoprotein metabolic process
0.42	GO:0032930	positive regulation of superoxide anion generation

0.53	GO:0046872	metal ion binding
0.47	GO:0001849	complement component C1q binding
0.42	GO:0046790	virion binding
0.42	GO:0042802	identical protein binding
0.42	GO:0030169	low-density lipoprotein particle binding
0.41	GO:0050750	low-density lipoprotein particle receptor binding

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|Q2HPN7|Q2HPN7_CHICK
Beta1,4-galactosyltransferase 7
Search

B4GALT7

0.96	Xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)

0.60	GO:0005975	carbohydrate metabolic process
0.57	GO:0006029	proteoglycan metabolic process
0.57	GO:0048147	negative regulation of fibroblast proliferation
0.52	GO:0006487	protein N-linked glycosylation
0.50	GO:0097435	supramolecular fiber organization
0.48	GO:0006024	glycosaminoglycan biosynthetic process
0.41	GO:0006491	N-glycan processing
0.36	GO:1903510	mucopolysaccharide metabolic process
0.34	GO:0044272	sulfur compound biosynthetic process
0.33	GO:0006082	organic acid metabolic process

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.58	GO:0140103	catalytic activity, acting on a glycoprotein
0.49	GO:0030145	manganese ion binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0005515	protein binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0005794	Golgi apparatus
0.35	GO:0098588	bounding membrane of organelle
0.34	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.65

EC:2.4

GO:0016757

sp|Q2HZ96|AT1B4_CHICK
Protein ATP1B4
Search

ATP1B4

0.79	Sodium/potassium-transporting ATPase subunit beta

0.71	GO:0006814	sodium ion transport
0.70	GO:0006813	potassium ion transport
0.41	GO:1903288	positive regulation of potassium ion import
0.41	GO:1903278	positive regulation of sodium ion export across plasma membrane
0.41	GO:2001141	regulation of RNA biosynthetic process
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0006883	cellular sodium ion homeostasis
0.40	GO:0086009	membrane repolarization
0.40	GO:0010468	regulation of gene expression
0.40	GO:1901018	positive regulation of potassium ion transmembrane transporter activity

0.40	GO:0051117	ATPase binding
0.40	GO:0005391	sodium:potassium-exchanging ATPase activity
0.39	GO:0001671	ATPase activator activity

0.83	GO:0005890	sodium:potassium-exchanging ATPase complex
0.50	GO:0005637	nuclear inner membrane
0.37	GO:0042470	melanosome
0.33	GO:0005901	caveola
0.33	GO:0070062	extracellular exosome

0.40

GO:0005391

tr|Q2HZD5|Q2HZD5_CHICK
Growth arrest and DNA-damage-inducible protein 45 gamma
Search

GADD45G

0.93	Growth arrest and DNA damage inducible gamma

0.73	GO:0051726	regulation of cell cycle
0.62	GO:0006950	response to stress
0.62	GO:1900745	positive regulation of p38MAPK cascade
0.61	GO:0000185	activation of MAPKKK activity
0.59	GO:0046330	positive regulation of JNK cascade
0.56	GO:0043065	positive regulation of apoptotic process
0.44	GO:0006469	negative regulation of protein kinase activity
0.44	GO:0000186	activation of MAPKK activity
0.40	GO:0007275	multicellular organism development
0.40	GO:0051597	response to methylmercury

0.38	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.37	GO:0047485	protein N-terminus binding
0.37	GO:0042802	identical protein binding
0.37	GO:0019900	kinase binding
0.36	GO:0046982	protein heterodimerization activity
0.34	GO:0017056	structural constituent of nuclear pore
0.33	GO:0003735	structural constituent of ribosome

0.61	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0012505	endomembrane system
0.32	GO:0031975	envelope
0.32	GO:0043234	protein complex

tr|Q2HZD6|Q2HZD6_CHICK
Growth arrest and DNA-damage-inducible protein 45 alpha
Search

GADD45A

0.97	Growth arrest and DNA-damage-inducible protein alpha

0.72	GO:0051726	regulation of cell cycle
0.64	GO:1900745	positive regulation of p38MAPK cascade
0.63	GO:0000185	activation of MAPKKK activity
0.61	GO:0006950	response to stress
0.61	GO:0046330	positive regulation of JNK cascade
0.58	GO:0043065	positive regulation of apoptotic process
0.55	GO:0071260	cellular response to mechanical stimulus
0.54	GO:0071479	cellular response to ionizing radiation
0.54	GO:2000379	positive regulation of reactive oxygen species metabolic process
0.53	GO:0007098	centrosome cycle

0.54	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.54	GO:0047485	protein N-terminus binding
0.51	GO:0019900	kinase binding
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0046982	protein heterodimerization activity
0.33	GO:0003735	structural constituent of ribosome

0.60	GO:0005634	nucleus
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.41	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle

tr|Q2I810|Q2I810_CHICK
NPY receptor Y6
Search

0.95	Neuropeptide Y receptor type 6

0.79	GO:0007218	neuropeptide signaling pathway
0.52	GO:0007631	feeding behavior
0.52	GO:0003151	outflow tract morphogenesis
0.51	GO:0019233	sensory perception of pain
0.51	GO:0008015	blood circulation
0.50	GO:0040014	regulation of multicellular organism growth
0.49	GO:0007626	locomotory behavior
0.45	GO:0006006	glucose metabolic process
0.43	GO:0007268	chemical synaptic transmission
0.42	GO:0065008	regulation of biological quality

0.83	GO:0004983	neuropeptide Y receptor activity
0.39	GO:0042923	neuropeptide binding
0.36	GO:0017046	peptide hormone binding
0.33	GO:0005515	protein binding

0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q2I811|Q2I811_CHICK
NK-lysin
Search

NKL

0.96

NK-lysin

0.63

GO:0006629

lipid metabolic process

sp|Q2IAL6|CTHL3_CHICK
Cathelicidin-3
Search

0.91	Cathelicidin

0.72	GO:0006952	defense response
0.51	GO:0009617	response to bacterium
0.47	GO:0019835	cytolysis
0.47	GO:0008219	cell death
0.47	GO:0010629	negative regulation of gene expression
0.46	GO:0051673	membrane disruption in other organism
0.45	GO:0006955	immune response
0.45	GO:0030593	neutrophil chemotaxis
0.44	GO:0042116	macrophage activation
0.44	GO:0002377	immunoglobulin production

0.49

GO:0001530

lipopolysaccharide binding

0.66	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q2IAL7|CTHL2_CHICK
Cathelicidin-2
Search

0.88	Cathelicidin antimicrobial peptide CATH6

0.72	GO:0006952	defense response
0.51	GO:0009617	response to bacterium
0.49	GO:0019835	cytolysis
0.49	GO:0008219	cell death
0.47	GO:0010629	negative regulation of gene expression
0.44	GO:0006955	immune response
0.43	GO:0051673	membrane disruption in other organism
0.42	GO:0030593	neutrophil chemotaxis
0.42	GO:0042116	macrophage activation
0.42	GO:0002377	immunoglobulin production

0.51

GO:0001530

lipopolysaccharide binding

0.66	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q2KN97|CYTSA_CHICK
Cytospin-A
Search

SPECC1L

0.85	Sperm antigen with calponin homology and coiled-coil domains 1 like

0.61	GO:0007155	cell adhesion
0.56	GO:0051301	cell division
0.56	GO:0007049	cell cycle
0.49	GO:0007026	negative regulation of microtubule depolymerization
0.48	GO:0097095	frontonasal suture morphogenesis
0.47	GO:0030835	negative regulation of actin filament depolymerization
0.47	GO:0060325	face morphogenesis
0.46	GO:0035023	regulation of Rho protein signal transduction
0.46	GO:0016477	cell migration
0.46	GO:0043547	positive regulation of GTPase activity

0.46	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.46	GO:0005096	GTPase activator activity
0.44	GO:0004674	protein serine/threonine kinase activity

0.65	GO:0005921	gap junction
0.65	GO:0005856	cytoskeleton
0.57	GO:0005829	cytosol
0.49	GO:0044446	intracellular organelle part
0.44	GO:0099512	supramolecular fiber
0.40	GO:0043234	protein complex

0.44

GO:0004674

tr|Q2LAI0|Q2LAI0_CHICK
Non-specific serine/threonine protein kinase
Search

PRKAA2

0.58	Non-specific serine/threonine protein kinase

0.63	GO:0006468	protein phosphorylation
0.62	GO:0071380	cellular response to prostaglandin E stimulus
0.61	GO:0042149	cellular response to glucose starvation
0.61	GO:0032007	negative regulation of TOR signaling
0.59	GO:0018209	peptidyl-serine modification
0.59	GO:0042752	regulation of circadian rhythm
0.58	GO:0042593	glucose homeostasis
0.57	GO:0010508	positive regulation of autophagy
0.56	GO:0014823	response to activity
0.56	GO:0043066	negative regulation of apoptotic process

0.70	GO:0004674	protein serine/threonine kinase activity
0.63	GO:0035173	histone kinase activity
0.56	GO:0003682	chromatin binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.50	GO:0060089	molecular transducer activity
0.45	GO:0050405	[acetyl-CoA carboxylase] kinase activity

0.58	GO:0016607	nuclear speck
0.49	GO:0031588	nucleotide-activated protein kinase complex
0.49	GO:0005794	Golgi apparatus
0.43	GO:0005829	cytosol
0.38	GO:0016324	apical plasma membrane
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.70

GO:0004674

sp|Q2LK54|COL12_CHICK
Collectin-12
Search

COLEC12

0.93	Collectin sub-family member 12

0.57	GO:0060355	positive regulation of cell adhesion molecule production
0.55	GO:0071360	cellular response to exogenous dsRNA
0.54	GO:0034138	toll-like receptor 3 signaling pathway
0.54	GO:0006910	phagocytosis, recognition
0.47	GO:0006955	immune response
0.35	GO:0009756	carbohydrate mediated signaling
0.34	GO:0051260	protein homooligomerization
0.34	GO:0006952	defense response
0.34	GO:0006898	receptor-mediated endocytosis
0.34	GO:0001570	vasculogenesis

0.69	GO:0030246	carbohydrate binding
0.55	GO:0030169	low-density lipoprotein particle binding
0.54	GO:0008329	signaling pattern recognition receptor activity
0.35	GO:0046872	metal ion binding
0.34	GO:0005044	scavenger receptor activity
0.32	GO:0036094	small molecule binding

0.69	GO:0005581	collagen trimer
0.36	GO:0070062	extracellular exosome
0.35	GO:0030666	endocytic vesicle membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q2LK94|COL11_CHICK
Collectin-11
Search

COLEC11

0.97	Collectin sub-family member 11

0.39	GO:0048856	anatomical structure development
0.39	GO:0032501	multicellular organismal process
0.36	GO:0001867	complement activation, lectin pathway
0.35	GO:0048863	stem cell differentiation
0.35	GO:0001667	ameboidal-type cell migration
0.35	GO:0050918	positive chemotaxis
0.34	GO:0006898	receptor-mediated endocytosis
0.34	GO:0000256	allantoin catabolic process
0.34	GO:0043043	peptide biosynthetic process
0.33	GO:0006508	proteolysis

0.45	GO:0005537	mannose binding
0.35	GO:0042056	chemoattractant activity
0.34	GO:0005198	structural molecule activity
0.34	GO:0004037	allantoicase activity
0.34	GO:0004252	serine-type endopeptidase activity
0.32	GO:0004867	serine-type endopeptidase inhibitor activity
0.32	GO:0042802	identical protein binding

0.75	GO:0005581	collagen trimer
0.41	GO:0005576	extracellular region
0.34	GO:0005840	ribosome
0.32	GO:0019012	virion
0.30	GO:0016021	integral component of membrane

0.34	EC:3.5.3.4	GO:0004037
0.34	KEGG:R02422	GO:0004037

sp|Q2LK95|COL10_CHICK
Collectin-10
Search

COLEC10

0.97	Collectin liver protein 1

0.60	GO:0050918	positive chemotaxis
0.59	GO:1904888	cranial skeletal system development
0.36	GO:0001867	complement activation, lectin pathway
0.35	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.35	GO:0010951	negative regulation of endopeptidase activity
0.35	GO:0009792	embryo development ending in birth or egg hatching
0.33	GO:0006508	proteolysis
0.33	GO:0034755	iron ion transmembrane transport
0.33	GO:0006898	receptor-mediated endocytosis
0.33	GO:0070207	protein homotrimerization

0.61	GO:0042056	chemoattractant activity
0.60	GO:0005537	mannose binding
0.37	GO:0005201	extracellular matrix structural constituent
0.35	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0070287	ferritin receptor activity
0.34	GO:0004252	serine-type endopeptidase activity
0.34	GO:0005044	scavenger receptor activity
0.33	GO:0046539	histamine N-methyltransferase activity
0.33	GO:0042302	structural constituent of cuticle
0.32	GO:0005164	tumor necrosis factor receptor binding

0.77	GO:0005581	collagen trimer
0.53	GO:0005615	extracellular space
0.40	GO:0005737	cytoplasm
0.37	GO:0005604	basement membrane
0.37	GO:0012505	endomembrane system
0.35	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0009986	cell surface
0.33	GO:0005887	integral component of plasma membrane
0.32	GO:0005694	chromosome

0.34	EC:3.4.21	GO:0004252
0.33	KEGG:R02155	GO:0046539

tr|Q2LK96|Q2LK96_CHICK
Lung lectin
Search

0.97	Pulmonary surfactant-associated protein A

0.61	GO:0007585	respiratory gaseous exchange
0.56	GO:0008228	opsonization
0.47	GO:0033189	response to vitamin A
0.46	GO:0071732	cellular response to nitric oxide
0.46	GO:0055093	response to hyperoxia
0.46	GO:0070741	response to interleukin-6
0.45	GO:0070849	response to epidermal growth factor
0.45	GO:0050766	positive regulation of phagocytosis
0.45	GO:0071260	cellular response to mechanical stimulus
0.45	GO:0032526	response to retinoic acid

0.55	GO:0030246	carbohydrate binding
0.42	GO:0046872	metal ion binding
0.39	GO:0005319	lipid transporter activity
0.39	GO:0004478	methionine adenosyltransferase activity
0.37	GO:0004888	transmembrane signaling receptor activity
0.36	GO:0005515	protein binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.71	GO:0005581	collagen trimer
0.54	GO:0005615	extracellular space
0.54	GO:0005578	proteinaceous extracellular matrix
0.46	GO:0031410	cytoplasmic vesicle
0.45	GO:0005783	endoplasmic reticulum
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.40	GO:0031984	organelle subcompartment
0.36	GO:0005887	integral component of plasma membrane
0.35	GO:0009986	cell surface
0.34	GO:0098805	whole membrane

0.39

EC:2.5.1.6

GO:0004478

sp|Q2LMP1|WNT3A_CHICK
Protein Wnt-3a
Search

0.10	Proto-oncogene Wnt-3

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.60	GO:0007498	mesoderm development
0.60	GO:0060322	head development
0.58	GO:0050922	negative regulation of chemotaxis
0.58	GO:0072089	stem cell proliferation
0.58	GO:0001649	osteoblast differentiation
0.58	GO:0010771	negative regulation of cell morphogenesis involved in differentiation
0.57	GO:0048729	tissue morphogenesis
0.57	GO:0061387	regulation of extent of cell growth

0.73	GO:0005102	receptor binding
0.53	GO:0030545	receptor regulator activity
0.53	GO:0019904	protein domain specific binding
0.50	GO:0039706	co-receptor binding
0.46	GO:0003713	transcription coactivator activity

0.76	GO:0005578	proteinaceous extracellular matrix
0.51	GO:1990851	Wnt-Frizzled-LRP5/6 complex
0.49	GO:0005615	extracellular space
0.45	GO:0009986	cell surface
0.38	GO:0005788	endoplasmic reticulum lumen
0.37	GO:1990909	Wnt signalosome
0.37	GO:0005640	nuclear outer membrane
0.37	GO:0005796	Golgi lumen
0.36	GO:0030666	endocytic vesicle membrane
0.36	GO:1903561	extracellular vesicle

tr|Q2MCJ7|Q2MCJ7_CHICK
Aquaporin-1
Search

AQP1

0.89	Aquaporin FA-CHIP

0.58	GO:0085018	maintenance of symbiont-containing vacuole by host
0.56	GO:0003097	renal water transport
0.56	GO:0072230	metanephric proximal straight tubule development
0.56	GO:0072232	metanephric proximal convoluted tubule segment 2 development
0.56	GO:0072220	metanephric descending thin limb development
0.56	GO:0051458	corticotropin secretion
0.56	GO:0021670	lateral ventricle development
0.55	GO:0055085	transmembrane transport
0.55	GO:0072239	metanephric glomerulus vasculature development
0.54	GO:0044241	lipid digestion

0.69	GO:0015267	channel activity
0.56	GO:0005372	water transmembrane transporter activity
0.54	GO:0035379	carbon dioxide transmembrane transporter activity
0.52	GO:0046875	ephrin receptor binding
0.48	GO:0015079	potassium ion transmembrane transporter activity
0.48	GO:0030184	nitric oxide transmembrane transporter activity
0.47	GO:0008519	ammonium transmembrane transporter activity
0.47	GO:0015168	glycerol transmembrane transporter activity
0.38	GO:0042802	identical protein binding

0.55	GO:0020003	symbiont-containing vacuole
0.55	GO:0009925	basal plasma membrane
0.53	GO:0005903	brush border
0.52	GO:0016324	apical plasma membrane
0.51	GO:0005901	caveola
0.51	GO:0070062	extracellular exosome
0.50	GO:0030424	axon
0.44	GO:0042383	sarcolemma
0.44	GO:0031253	cell projection membrane
0.43	GO:0031965	nuclear membrane

tr|Q2NNA5|Q2NNA5_CHICK
Noggin4
Search

0.79

Noggin

0.85	GO:0030514	negative regulation of BMP signaling pathway
0.79	GO:0045596	negative regulation of cell differentiation
0.70	GO:0051216	cartilage development
0.61	GO:0030154	cell differentiation

0.57	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|Q2PC93|SSPO_CHICK
SCO-spondin
Search

SSPO

0.70	SCO-spondin

0.74	GO:0007399	nervous system development
0.72	GO:0030154	cell differentiation
0.53	GO:0010466	negative regulation of peptidase activity
0.42	GO:0007155	cell adhesion
0.38	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression
0.32	GO:0006030	chitin metabolic process
0.32	GO:0022900	electron transport chain

0.53	GO:0030414	peptidase inhibitor activity
0.38	GO:0004930	G-protein coupled receptor activity
0.35	GO:0046983	protein dimerization activity
0.33	GO:0003676	nucleic acid binding
0.33	GO:0000293	ferric-chelate reductase activity
0.32	GO:0008061	chitin binding

0.43	GO:0005615	extracellular space
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33

EC:1.16.1.7

GO:0000293

tr|Q2PUH1|Q2PUH1_CHICK
Non-specific serine/threonine protein kinase
Search

PRKAA1

0.58	Non-specific serine/threonine protein kinase

0.63	GO:0006468	protein phosphorylation
0.59	GO:0071380	cellular response to prostaglandin E stimulus
0.58	GO:0042149	cellular response to glucose starvation
0.57	GO:0061762	CAMKK-AMPK signaling cascade
0.57	GO:0032007	negative regulation of TOR signaling
0.56	GO:0042752	regulation of circadian rhythm
0.56	GO:1901563	response to camptothecin
0.56	GO:0018209	peptidyl-serine modification
0.55	GO:0050995	negative regulation of lipid catabolic process
0.55	GO:0042593	glucose homeostasis

0.70	GO:0004674	protein serine/threonine kinase activity
0.59	GO:0035173	histone kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0003682	chromatin binding
0.48	GO:0060089	molecular transducer activity
0.44	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.43	GO:0050405	[acetyl-CoA carboxylase] kinase activity

0.55	GO:0016607	nuclear speck
0.47	GO:0005829	cytosol
0.43	GO:0031588	nucleotide-activated protein kinase complex
0.41	GO:0005794	Golgi apparatus
0.38	GO:0016324	apical plasma membrane
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.70

GO:0004674

tr|Q2PYN4|Q2PYN4_CHICK
Interleukin 9
Search

IL9

0.90	Interleukin 9

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response

0.79	GO:0005126	cytokine receptor binding
0.78	GO:0008083	growth factor activity

0.66

GO:0005576

extracellular region

tr|Q2THW3|Q2THW3_CHICK
Palmitoyltransferase
Search

ZDHHC8

0.56	Palmitoyltransferase

0.84	GO:0018345	protein palmitoylation
0.53	GO:1903146	regulation of autophagy of mitochondrion
0.52	GO:1903955	positive regulation of protein targeting to mitochondrion
0.50	GO:0007626	locomotory behavior
0.35	GO:0034380	high-density lipoprotein particle assembly

0.79	GO:0016409	palmitoyltransferase activity
0.79	GO:0019707	protein-cysteine S-acyltransferase activity
0.33	GO:0005515	protein binding

0.48	GO:0005794	Golgi apparatus
0.43	GO:0030425	dendrite
0.42	GO:0005739	mitochondrion
0.37	GO:0030659	cytoplasmic vesicle membrane
0.37	GO:0005886	plasma membrane
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.79

GO:0016409

tr|Q2TV23|Q2TV23_CHICK
Cryptochrome-like protein
Search

CRY1

0.26	Cryptochrome circadian clock 4

0.62	GO:0009416	response to light stimulus
0.61	GO:0045892	negative regulation of transcription, DNA-templated
0.61	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway
0.61	GO:0006975	DNA damage induced protein phosphorylation
0.60	GO:0009649	entrainment of circadian clock
0.60	GO:0033762	response to glucagon
0.60	GO:2000847	negative regulation of corticosteroid hormone secretion
0.59	GO:0042754	negative regulation of circadian rhythm
0.59	GO:2000001	regulation of DNA damage checkpoint
0.58	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway

0.58	GO:0035257	nuclear hormone receptor binding
0.56	GO:0001047	core promoter binding
0.56	GO:0042826	histone deacetylase binding
0.55	GO:0019902	phosphatase binding
0.52	GO:0019901	protein kinase binding
0.52	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.52	GO:0009881	photoreceptor activity
0.52	GO:0000989	transcription factor activity, transcription factor binding
0.47	GO:0016829	lyase activity
0.38	GO:0140097	catalytic activity, acting on DNA

0.50	GO:0005634	nucleus
0.44	GO:0005739	mitochondrion
0.41	GO:0005829	cytosol
0.38	GO:0005667	transcription factor complex
0.38	GO:0097381	photoreceptor disc membrane
0.38	GO:0042622	photoreceptor outer segment membrane
0.30	GO:0016021	integral component of membrane

0.47

EC:4

GO:0016829

sp|Q2VB19|PUM1_CHICK
Pumilio homolog 1
Search

PUM1

0.97	Pumilio like protein 1

0.58	GO:1900246	positive regulation of RIG-I signaling pathway
0.57	GO:2000637	positive regulation of gene silencing by miRNA
0.56	GO:0061157	mRNA destabilization
0.55	GO:0035196	production of miRNAs involved in gene silencing by miRNA
0.54	GO:0008344	adult locomotory behavior
0.54	GO:0048863	stem cell differentiation
0.53	GO:0007283	spermatogenesis
0.52	GO:0051983	regulation of chromosome segregation
0.49	GO:0051726	regulation of cell cycle

0.59	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.54	GO:0000932	P-body
0.53	GO:0016607	nuclear speck
0.53	GO:0010494	cytoplasmic stress granule
0.48	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q2VRL0|PLCZ1_CHICK
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1
Search

PLCZ1

0.52	Phosphoinositide phospholipase C

0.82	GO:0007343	egg activation
0.72	GO:0016042	lipid catabolic process
0.71	GO:0006816	calcium ion transport
0.62	GO:0035556	intracellular signal transduction
0.51	GO:0007340	acrosome reaction
0.46	GO:0046488	phosphatidylinositol metabolic process
0.41	GO:0001525	angiogenesis
0.40	GO:0042127	regulation of cell proliferation
0.33	GO:0050913	sensory perception of bitter taste

0.81	GO:0004435	phosphatidylinositol phospholipase C activity
0.63	GO:0004871	signal transducer activity
0.53	GO:0005509	calcium ion binding

0.64	GO:0005829	cytosol
0.38	GO:0031965	nuclear membrane
0.35	GO:0005886	plasma membrane

0.81	EC:3.1.4.11	GO:0004435
0.81	KEGG:R03435	GO:0004435

tr|Q2XP49|Q2XP49_CHICK
Deoxyribonuclease II
Search

DNASE2B

0.79	Deoxyribonuclease II beta

0.60	GO:0006259	DNA metabolic process
0.50	GO:0030262	apoptotic nuclear changes
0.44	GO:0034655	nucleobase-containing compound catabolic process
0.44	GO:0044265	cellular macromolecule catabolic process
0.42	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.36	GO:0030218	erythrocyte differentiation

0.84

GO:0004531

deoxyribonuclease II activity

0.48	GO:0005576	extracellular region
0.39	GO:0005737	cytoplasm
0.34	GO:0043231	intracellular membrane-bounded organelle

0.84

EC:3.1.22.1

GO:0004531

sp|Q2YHT5|MOR1B_CHICK
Cell surface glycoprotein CD200 receptor 1-B
Search

0.96	Cell surface glycoprotein CD200 receptor 1-B

0.37	GO:0007286	spermatid development
0.35	GO:0007155	cell adhesion
0.35	GO:0030260	entry into host cell
0.34	GO:0019058	viral life cycle

0.53	GO:0004872	receptor activity
0.36	GO:0050839	cell adhesion molecule binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0046982	protein heterodimerization activity

0.65	GO:0009897	external side of plasma membrane
0.41	GO:0005576	extracellular region
0.36	GO:0005911	cell-cell junction
0.30	GO:0031224	intrinsic component of membrane

sp|Q2YHT7|MOR1A_CHICK
Cell surface glycoprotein CD200 receptor 1-A
Search

0.96	Cell surface glycoprotein CD200 receptor 1-A

0.54

GO:0060089

molecular transducer activity

0.66	GO:0009897	external side of plasma membrane
0.50	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q2Z1W2|CENPU_CHICK
Centromere protein U
Search

CENPU

0.96	Centromere protein U

0.61	GO:0043009	chordate embryonic development
0.30	GO:0008152	metabolic process

0.44

GO:0016874

ligase activity

0.63	GO:0005815	microtubule organizing center
0.55	GO:0005634	nucleus
0.46	GO:0000775	chromosome, centromeric region
0.42	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.44

GO:0016874

tr|Q309X7|Q309X7_CHICK
G protein-coupled pituitary GHRH receptor
Search

GHRHR

0.97	Pituitary growth hormone-releasing hormone receptor

0.69	GO:0007166	cell surface receptor signaling pathway
0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.53	GO:0060133	somatotropin secreting cell development
0.52	GO:0030252	growth hormone secretion
0.52	GO:0060124	positive regulation of growth hormone secretion
0.51	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.51	GO:0040018	positive regulation of multicellular organism growth
0.50	GO:0030104	water homeostasis
0.50	GO:0043627	response to estrogen
0.50	GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway

0.70	GO:0004930	G-protein coupled receptor activity
0.51	GO:0017046	peptide hormone binding
0.49	GO:0019838	growth factor binding
0.33	GO:0005509	calcium ion binding

0.51	GO:0005640	nuclear outer membrane
0.49	GO:0005886	plasma membrane
0.49	GO:0016363	nuclear matrix
0.49	GO:0005637	nuclear inner membrane
0.48	GO:0030141	secretory granule
0.47	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

tr|Q30D05|Q30D05_CHICK
Neuropeptide Y7 receptor
Search

0.94	Neuropeptide Y receptor type 2

0.79	GO:0007218	neuropeptide signaling pathway
0.50	GO:0003214	cardiac left ventricle morphogenesis
0.48	GO:0003151	outflow tract morphogenesis
0.46	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.41	GO:0007631	feeding behavior
0.39	GO:0007268	chemical synaptic transmission
0.37	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep
0.37	GO:0033603	positive regulation of dopamine secretion
0.36	GO:2000252	negative regulation of feeding behavior
0.36	GO:0051967	negative regulation of synaptic transmission, glutamatergic

0.83	GO:0004983	neuropeptide Y receptor activity
0.47	GO:0042923	neuropeptide binding
0.34	GO:0005246	calcium channel regulator activity
0.33	GO:0005515	protein binding

0.46	GO:0097730	non-motile cilium
0.35	GO:0005886	plasma membrane
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q32TG3|EFHC2_CHICK
EF-hand domain-containing family member C2
Search

EFHC2

0.85	EF-hand domain-containing family member C2

0.54	GO:1990823	response to leukemia inhibitory factor
0.52	GO:0071345	cellular response to cytokine stimulus

0.64	GO:0005509	calcium ion binding
0.38	GO:0005515	protein binding

0.43	GO:0005615	extracellular space
0.30	GO:0005623	cell

tr|Q334G8|Q334G8_CHICK
Putative C-X-C chemokine receptor type 1, CXCR1
Search

CXCR1

0.97	C-X-C motif chemokine receptor 1

0.84	GO:0070098	chemokine-mediated signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.71	GO:0006935	chemotaxis
0.54	GO:0038112	interleukin-8-mediated signaling pathway
0.50	GO:0031623	receptor internalization
0.47	GO:0042119	neutrophil activation
0.46	GO:0006968	cellular defense response
0.46	GO:0050900	leukocyte migration
0.43	GO:0008284	positive regulation of cell proliferation
0.42	GO:0043066	negative regulation of apoptotic process

0.84	GO:0016494	C-X-C chemokine receptor activity
0.74	GO:0019959	interleukin-8 binding
0.41	GO:0016493	C-C chemokine receptor activity
0.39	GO:0005044	scavenger receptor activity
0.37	GO:0051916	granulocyte colony-stimulating factor binding
0.36	GO:0019957	C-C chemokine binding
0.36	GO:0015026	coreceptor activity
0.34	GO:0008289	lipid binding
0.32	GO:0003924	GTPase activity
0.32	GO:0005525	GTP binding

0.46	GO:0042629	mast cell granule
0.43	GO:0009986	cell surface
0.39	GO:0005886	plasma membrane
0.36	GO:0030667	secretory granule membrane
0.36	GO:0097225	sperm midpiece
0.36	GO:0097228	sperm principal piece
0.34	GO:0098552	side of membrane
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

tr|Q38Q38|Q38Q38_CHICK
Bradykinin receptor B1
Search

BDKRB1

0.94	B1 like bradykinin receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.68	GO:0006954	inflammatory response
0.68	GO:0009612	response to mechanical stimulus
0.58	GO:0010033	response to organic substance
0.53	GO:0009617	response to bacterium
0.51	GO:1901700	response to oxygen-containing compound
0.48	GO:0007166	cell surface receptor signaling pathway
0.48	GO:0006935	chemotaxis
0.48	GO:0070887	cellular response to chemical stimulus
0.47	GO:0002685	regulation of leukocyte migration

0.76	GO:0008528	G-protein coupled peptide receptor activity
0.55	GO:0042277	peptide binding
0.53	GO:0004896	cytokine receptor activity
0.41	GO:0019956	chemokine binding
0.33	GO:0004878	complement component C5a receptor activity
0.33	GO:0016907	G-protein coupled acetylcholine receptor activity

0.41	GO:0043005	neuron projection
0.40	GO:0005886	plasma membrane
0.38	GO:0009986	cell surface
0.38	GO:0098552	side of membrane
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

tr|Q3BKZ5|Q3BKZ5_CHICK
CD86
Search

CD86

0.97	T-lymphocyte activation antigen CD86

0.54	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part

sp|Q3C1E9|ASF1_CHICK
Histone chaperone ASF1
Search

ASF1A

0.90	Anti-silencing function 1Ba histone chaperone

0.76	GO:0006333	chromatin assembly or disassembly
0.61	GO:0034728	nucleosome organization
0.60	GO:0065004	protein-DNA complex assembly
0.59	GO:0001649	osteoblast differentiation
0.59	GO:0006323	DNA packaging
0.57	GO:0042692	muscle cell differentiation
0.48	GO:0006281	DNA repair
0.45	GO:0016569	covalent chromatin modification
0.38	GO:0032986	protein-DNA complex disassembly
0.38	GO:0006351	transcription, DNA-templated

0.62	GO:0042393	histone binding
0.55	GO:0003682	chromatin binding

0.60	GO:0005634	nucleus
0.56	GO:0000785	chromatin
0.53	GO:0031974	membrane-enclosed lumen
0.48	GO:0043234	protein complex

tr|Q3C2H5|Q3C2H5_CHICK
Sine oculis-related homeobox 1 homolog
Search

SIX1

0.96	SIX homeobox 1

0.75	GO:0072074	kidney mesenchyme development
0.74	GO:0042474	middle ear morphogenesis
0.74	GO:0090189	regulation of branching involved in ureteric bud morphogenesis
0.73	GO:0008283	cell proliferation
0.72	GO:0072088	nephron epithelium morphogenesis
0.72	GO:0001656	metanephros development
0.71	GO:0048701	embryonic cranial skeleton morphogenesis
0.70	GO:0001708	cell fate specification
0.67	GO:0034504	protein localization to nucleus
0.67	GO:0035239	tube morphogenesis

0.69	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.68	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0003682	chromatin binding
0.52	GO:0032403	protein complex binding
0.52	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.56	GO:0005667	transcription factor complex
0.51	GO:0070013	intracellular organelle lumen
0.47	GO:0043232	intracellular non-membrane-bounded organelle
0.46	GO:0044446	intracellular organelle part

tr|Q3C2H6|Q3C2H6_CHICK
Protein Wnt
Search

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.56	GO:0070172	positive regulation of tooth mineralization
0.56	GO:0060684	epithelial-mesenchymal cell signaling
0.52	GO:0061138	morphogenesis of a branching epithelium
0.49	GO:0048646	anatomical structure formation involved in morphogenesis
0.48	GO:0045893	positive regulation of transcription, DNA-templated
0.47	GO:0045165	cell fate commitment
0.35	GO:0071300	cellular response to retinoic acid
0.33	GO:0043433	negative regulation of DNA binding transcription factor activity

0.73	GO:0005102	receptor binding
0.33	GO:0030545	receptor regulator activity

0.76	GO:0005578	proteinaceous extracellular matrix
0.49	GO:0009986	cell surface
0.44	GO:0005615	extracellular space
0.37	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0005796	Golgi lumen
0.35	GO:0030666	endocytic vesicle membrane
0.35	GO:1903561	extracellular vesicle
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q3HS34|Q3HS34_CHICK
Ovarian prostaglandin F receptor
Search

PTGFR

0.97	Ovarian prostaglandin F receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.62	GO:0071798	response to prostaglandin D
0.60	GO:0071379	cellular response to prostaglandin stimulus
0.59	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.58	GO:0032355	response to estradiol
0.58	GO:0032496	response to lipopolysaccharide
0.54	GO:0008284	positive regulation of cell proliferation
0.54	GO:0043066	negative regulation of apoptotic process
0.51	GO:0010628	positive regulation of gene expression
0.41	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis

0.85	GO:0004958	prostaglandin F receptor activity
0.56	GO:0004960	thromboxane receptor activity
0.49	GO:0004957	prostaglandin E receptor activity
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.32	GO:0005515	protein binding

0.48	GO:0005576	extracellular region
0.44	GO:0005886	plasma membrane
0.40	GO:0005737	cytoplasm
0.39	GO:0016607	nuclear speck
0.35	GO:0097223	sperm part
0.34	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system
0.30	GO:0016021	integral component of membrane

0.33

GO:0016620

sp|Q3KTM2|GDPD5_CHICK
Glycerophosphodiester phosphodiesterase domain-containing protein 5
Search

GDPD5

0.96	Glycerophosphodiester phosphodiesterase domain-containing protein 5

0.62	GO:0006629	lipid metabolic process
0.52	GO:0048505	regulation of timing of cell differentiation
0.52	GO:0021895	cerebral cortex neuron differentiation
0.51	GO:0021522	spinal cord motor neuron differentiation
0.51	GO:0045746	negative regulation of Notch signaling pathway
0.49	GO:0045666	positive regulation of neuron differentiation
0.48	GO:0045787	positive regulation of cell cycle
0.48	GO:0031175	neuron projection development

0.77	GO:0008889	glycerophosphodiester phosphodiesterase activity
0.51	GO:0047389	glycerophosphocholine phosphodiesterase activity
0.34	GO:0005515	protein binding

0.51	GO:0097038	perinuclear endoplasmic reticulum
0.49	GO:0043025	neuronal cell body
0.48	GO:0030424	axon
0.38	GO:0030426	growth cone
0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.77

EC:3.1.4.46

GO:0008889

sp|Q3L254|WNT7B_CHICK
Protein Wnt-7b
Search

tr|Q3MUH5|Q3MUH5_CHICK
Fanconi anemia protein FANCL
Search

FANCL

0.90	Fanconi anemia complementation group L

0.73	GO:0016567	protein ubiquitination
0.65	GO:0007276	gamete generation
0.65	GO:0006281	DNA repair
0.58	GO:0042127	regulation of cell proliferation
0.51	GO:0022412	cellular process involved in reproduction in multicellular organism
0.50	GO:0003006	developmental process involved in reproduction
0.50	GO:0048468	cell development

0.74	GO:0004842	ubiquitin-protein transferase activity
0.61	GO:0031625	ubiquitin protein ligase binding
0.59	GO:0061659	ubiquitin-like protein ligase activity

0.85	GO:0043240	Fanconi anaemia nuclear complex
0.60	GO:0016604	nuclear body
0.57	GO:0005635	nuclear envelope
0.30	GO:0031224	intrinsic component of membrane

0.74

KEGG:R03876

GO:0004842

sp|Q3V6R6|CETP_CHICK
Cholesteryl ester transfer protein
Search

CETP

0.97	Cholesteryl ester transfer protein, plasma

0.86	GO:0043691	reverse cholesterol transport
0.62	GO:0034197	triglyceride transport
0.61	GO:0034372	very-low-density lipoprotein particle remodeling
0.60	GO:0034375	high-density lipoprotein particle remodeling
0.58	GO:0034374	low-density lipoprotein particle remodeling
0.57	GO:0055091	phospholipid homeostasis
0.57	GO:0010874	regulation of cholesterol efflux
0.57	GO:0008203	cholesterol metabolic process
0.56	GO:0070328	triglyceride homeostasis
0.55	GO:0042632	cholesterol homeostasis

0.85	GO:0017127	cholesterol transporter activity
0.72	GO:0008289	lipid binding
0.57	GO:0050997	quaternary ammonium group binding
0.54	GO:0070405	ammonium ion binding
0.54	GO:0043178	alcohol binding
0.53	GO:0005548	phospholipid transporter activity
0.41	GO:0043168	anion binding
0.37	GO:0097159	organic cyclic compound binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding

0.85	GO:0034364	high-density lipoprotein particle
0.49	GO:0031982	vesicle
0.35	GO:0043230	extracellular organelle
0.30	GO:0016020	membrane

tr|Q3Y8N1|Q3Y8N1_CHICK
Deoxyribonuclease
Search

DNASE1L3

0.63	Deoxyribonuclease gamma

0.76	GO:0006308	DNA catabolic process
0.61	GO:0070948	regulation of neutrophil mediated cytotoxicity
0.59	GO:0002283	neutrophil activation involved in immune response
0.58	GO:0002673	regulation of acute inflammatory response
0.56	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.55	GO:0030262	apoptotic nuclear changes
0.54	GO:0010623	programmed cell death involved in cell development
0.36	GO:0002088	lens development in camera-type eye
0.36	GO:0060041	retina development in camera-type eye
0.36	GO:0003335	corneocyte development

0.71	GO:0004536	deoxyribonuclease activity
0.57	GO:0004519	endonuclease activity
0.36	GO:0003779	actin binding
0.34	GO:0003677	DNA binding
0.33	GO:0005509	calcium ion binding

0.47	GO:0005783	endoplasmic reticulum
0.45	GO:0005634	nucleus
0.38	GO:0005576	extracellular region
0.35	GO:0031967	organelle envelope
0.34	GO:0031982	vesicle
0.30	GO:0016020	membrane

sp|Q3YK19|FANCJ_CHICK
Fanconi anemia group J protein homolog
Search

BRIP1

0.83	Fanconi anemia group J

0.70	GO:0032392	DNA geometric change
0.49	GO:1901360	organic cyclic compound metabolic process
0.49	GO:0046483	heterocycle metabolic process
0.49	GO:0006725	cellular aromatic compound metabolic process
0.47	GO:0007284	spermatogonial cell division
0.46	GO:0072520	seminiferous tubule development
0.45	GO:0006807	nitrogen compound metabolic process
0.44	GO:0007129	synapsis
0.44	GO:0007286	spermatid development
0.41	GO:0006357	regulation of transcription by RNA polymerase II

0.72	GO:0004003	ATP-dependent DNA helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0051539	4 iron, 4 sulfur cluster binding
0.38	GO:0003682	chromatin binding
0.36	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.40	GO:0012505	endomembrane system
0.38	GO:0031967	organelle envelope
0.38	GO:0031090	organelle membrane
0.38	GO:0031974	membrane-enclosed lumen
0.35	GO:0005737	cytoplasm

sp|Q401C0|CNIH2_CHICK
Protein cornichon homolog 2
Search

CNIH2

0.97	Cornichon family AMPA receptor auxiliary protein 2

0.67	GO:0016192	vesicle-mediated transport
0.63	GO:2000311	regulation of AMPA receptor activity
0.44	GO:0035249	synaptic transmission, glutamatergic
0.42	GO:1903743	negative regulation of anterograde synaptic vesicle transport
0.42	GO:1902684	negative regulation of receptor localization to synapse
0.41	GO:0042391	regulation of membrane potential
0.41	GO:2000310	regulation of NMDA receptor activity
0.40	GO:0051668	localization within membrane
0.36	GO:0051650	establishment of vesicle localization
0.36	GO:0016050	vesicle organization

0.40	GO:0016247	channel regulator activity
0.35	GO:0005515	protein binding

0.51	GO:0043197	dendritic spine
0.50	GO:0014069	postsynaptic density
0.44	GO:0032281	AMPA glutamate receptor complex
0.44	GO:0043198	dendritic shaft
0.42	GO:0045211	postsynaptic membrane
0.39	GO:0030054	cell junction
0.37	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.36	GO:0012507	ER to Golgi transport vesicle membrane
0.35	GO:0000139	Golgi membrane

sp|Q45KJ4|LN28B_CHICK
Protein lin-28 homolog B
Search

LIN28B

0.97	Lin-28 like protein B

0.61	GO:0010587	miRNA catabolic process
0.60	GO:0031054	pre-miRNA processing
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:0031123	RNA 3'-end processing
0.48	GO:2000767	positive regulation of cytoplasmic translation
0.47	GO:1901724	positive regulation of cell proliferation involved in kidney development
0.46	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA
0.46	GO:0045686	negative regulation of glial cell differentiation
0.45	GO:0019827	stem cell population maintenance
0.45	GO:0071333	cellular response to glucose stimulus

0.63	GO:0008270	zinc ion binding
0.55	GO:0003677	DNA binding
0.49	GO:1905538	polysome binding
0.46	GO:1990825	sequence-specific mRNA binding
0.46	GO:0035198	miRNA binding
0.45	GO:0002151	G-quadruplex RNA binding
0.44	GO:0031369	translation initiation factor binding

0.51	GO:0005730	nucleolus
0.46	GO:0005829	cytosol
0.45	GO:0005844	polysome
0.45	GO:0000932	P-body
0.45	GO:0010494	cytoplasmic stress granule
0.44	GO:0005791	rough endoplasmic reticulum

sp|Q45KJ5|LN28A_CHICK
Protein lin-28 homolog A
Search

LIN28A

0.38	Pleuripotency maintenance factor

0.61	GO:0010587	miRNA catabolic process
0.59	GO:0031054	pre-miRNA processing
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000767	positive regulation of cytoplasmic translation
0.53	GO:1901724	positive regulation of cell proliferation involved in kidney development
0.53	GO:0031123	RNA 3'-end processing
0.52	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA
0.52	GO:0019827	stem cell population maintenance
0.51	GO:0045686	negative regulation of glial cell differentiation
0.50	GO:0071333	cellular response to glucose stimulus

0.63	GO:0008270	zinc ion binding
0.56	GO:1905538	polysome binding
0.55	GO:0003677	DNA binding
0.52	GO:1990825	sequence-specific mRNA binding
0.51	GO:0035198	miRNA binding
0.51	GO:0002151	G-quadruplex RNA binding
0.49	GO:0031369	translation initiation factor binding

0.52	GO:0005844	polysome
0.51	GO:0000932	P-body
0.51	GO:0010494	cytoplasmic stress granule
0.51	GO:0005730	nucleolus
0.50	GO:0005791	rough endoplasmic reticulum
0.42	GO:0005829	cytosol

tr|Q49B65|Q49B65_CHICK
EF hand-containing protein 1
Search

EFHD1

0.96	EF hand-containing protein 1

0.47	GO:0031175	neuron projection development
0.36	GO:0006413	translational initiation
0.33	GO:0048009	insulin-like growth factor receptor signaling pathway
0.33	GO:0061157	mRNA destabilization
0.33	GO:0048873	homeostasis of number of cells within a tissue
0.33	GO:0050881	musculoskeletal movement
0.33	GO:0021522	spinal cord motor neuron differentiation
0.33	GO:0031571	mitotic G1 DNA damage checkpoint
0.33	GO:0050885	neuromuscular process controlling balance
0.33	GO:0035264	multicellular organism growth

0.70	GO:0005509	calcium ion binding
0.45	GO:0045296	cadherin binding
0.36	GO:0003743	translation initiation factor activity
0.33	GO:0070064	proline-rich region binding

0.42	GO:0019866	organelle inner membrane
0.42	GO:0031966	mitochondrial membrane
0.37	GO:0045121	membrane raft
0.36	GO:0070062	extracellular exosome
0.33	GO:1990635	proximal dendrite
0.33	GO:0043204	perikaryon
0.33	GO:0010494	cytoplasmic stress granule
0.32	GO:0005768	endosome
0.32	GO:0005794	Golgi apparatus
0.32	GO:0005783	endoplasmic reticulum

tr|Q49M60|Q49M60_CHICK
XK-related protein
Search

tr|Q4ADW2|Q4ADW2_CHICK
Endothelial protein C receptor
Search

PROCR

0.97	Endothelial cell protein C receptor

0.59	GO:0050819	negative regulation of coagulation
0.39	GO:0007596	blood coagulation
0.36	GO:0050900	leukocyte migration

0.65	GO:0004872	receptor activity
0.34	GO:0005515	protein binding

0.51	GO:0005813	centrosome
0.37	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome
0.36	GO:0009986	cell surface
0.34	GO:0005887	integral component of plasma membrane

tr|Q4F8N2|Q4F8N2_CHICK
Otoconin
Search

OC90

0.44

Otoconin

0.82	GO:1903963	arachidonate transport
0.82	GO:0032309	icosanoid secretion
0.72	GO:0016042	lipid catabolic process
0.67	GO:0006644	phospholipid metabolic process
0.35	GO:0048840	otolith development

0.82	GO:0004623	phospholipase A2 activity
0.70	GO:0005509	calcium ion binding
0.51	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.51	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.42	GO:0005198	structural molecule activity

0.66	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.82

EC:3.1.1.4

GO:0004623

sp|Q4JIM4|PSN1_CHICK
Presenilin-1
Search

PSEN1

0.80	Presenilin

0.81	GO:0007219	Notch signaling pathway
0.77	GO:0042987	amyloid precursor protein catabolic process
0.75	GO:0016485	protein processing
0.60	GO:0050435	amyloid-beta metabolic process
0.59	GO:0051563	smooth endoplasmic reticulum calcium ion homeostasis
0.59	GO:1904797	negative regulation of core promoter binding
0.59	GO:0006509	membrane protein ectodomain proteolysis
0.58	GO:0021870	Cajal-Retzius cell differentiation
0.58	GO:1905908	positive regulation of amyloid fibril formation
0.58	GO:0002265	astrocyte activation involved in immune response

0.76	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving
0.54	GO:0008013	beta-catenin binding
0.54	GO:0030165	PDZ domain binding
0.53	GO:0045296	cadherin binding
0.51	GO:0005262	calcium channel activity
0.34	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0003723	RNA binding

0.73	GO:0000139	Golgi membrane
0.71	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.71	GO:0098827	endoplasmic reticulum subcompartment
0.58	GO:0070765	gamma-secretase complex
0.57	GO:0005790	smooth endoplasmic reticulum
0.57	GO:0035253	ciliary rootlet
0.56	GO:0043198	dendritic shaft
0.56	GO:0016235	aggresome
0.55	GO:0030426	growth cone
0.53	GO:0098857	membrane microdomain

0.76

EC:3.4.23

GO:0042500

tr|Q4JQQ0|Q4JQQ0_CHICK
Caspase-18/a
Search

0.64	Initiator caspase

0.75	GO:0006915	apoptotic process
0.70	GO:0042981	regulation of apoptotic process
0.61	GO:0006508	proteolysis
0.41	GO:0030225	macrophage differentiation
0.40	GO:0045651	positive regulation of macrophage differentiation
0.40	GO:0007166	cell surface receptor signaling pathway
0.40	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.39	GO:0071260	cellular response to mechanical stimulus
0.39	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.39	GO:2001056	positive regulation of cysteine-type endopeptidase activity

0.75	GO:0004197	cysteine-type endopeptidase activity
0.42	GO:0035877	death effector domain binding
0.40	GO:0097110	scaffold protein binding
0.39	GO:0031625	ubiquitin protein ligase binding
0.38	GO:0004871	signal transducer activity
0.37	GO:0042802	identical protein binding
0.34	GO:0005123	death receptor binding
0.33	GO:0005164	tumor necrosis factor receptor binding
0.33	GO:0004386	helicase activity
0.33	GO:0032403	protein complex binding

0.42	GO:0097342	ripoptosome
0.41	GO:0031265	CD95 death-inducing signaling complex
0.38	GO:0005654	nucleoplasm
0.33	GO:0044297	cell body
0.33	GO:0098857	membrane microdomain
0.33	GO:0005741	mitochondrial outer membrane
0.33	GO:0043005	neuron projection
0.32	GO:0005856	cytoskeleton
0.30	GO:0016021	integral component of membrane

0.75

GO:0004197

tr|Q4KS30|Q4KS30_CHICK
C-C motif chemokine 4 homolog
Search

0.75	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.72	GO:0010469	regulation of receptor activity
0.57	GO:0070098	chemokine-mediated signaling pathway
0.57	GO:0006954	inflammatory response
0.51	GO:0050900	leukocyte migration
0.50	GO:0071347	cellular response to interleukin-1
0.49	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.49	GO:0071356	cellular response to tumor necrosis factor
0.47	GO:0009615	response to virus

0.84	GO:0008009	chemokine activity
0.60	GO:0048020	CCR chemokine receptor binding
0.43	GO:0042056	chemoattractant activity
0.39	GO:0004698	calcium-dependent protein kinase C activity
0.39	GO:0016004	phospholipase activator activity

0.70	GO:0005615	extracellular space
0.36	GO:0005829	cytosol
0.30	GO:0044425	membrane part

0.39