Queries 23001 to 24000

GO:0004674

tr|Q7T2F4|Q7T2F4_DANRE
Novel protein (Zgc:63913)
Search

0.96	Signal-transducing adaptor protein 2

0.40

GO:0005886

plasma membrane

tr|Q7T2F5|Q7T2F5_DANRE
N-ethylmaleimide sensitive fusion protein attachment protein alpha
Search

NAPA

0.87	N-ethylmaleimide sensitive fusion protein attachment protein alpha

0.68	GO:0006886	intracellular protein transport
0.63	GO:0035494	SNARE complex disassembly
0.62	GO:0010807	regulation of synaptic vesicle priming
0.60	GO:0035249	synaptic transmission, glutamatergic
0.52	GO:0045176	apical protein localization
0.49	GO:0007420	brain development
0.48	GO:0030182	neuron differentiation
0.46	GO:0061025	membrane fusion
0.39	GO:0043462	regulation of ATPase activity
0.37	GO:0051345	positive regulation of hydrolase activity

0.60	GO:0019905	syntaxin binding
0.54	GO:0005483	soluble NSF attachment protein activity
0.37	GO:0032403	protein complex binding
0.32	GO:0003677	DNA binding

0.62	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex
0.57	GO:0043209	myelin sheath
0.49	GO:0005774	vacuolar membrane
0.39	GO:0043195	terminal bouton
0.38	GO:0070062	extracellular exosome
0.34	GO:0005886	plasma membrane
0.34	GO:0000139	Golgi membrane
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus

sp|Q7T2F6|WSB1_DANRE
WD repeat and SOCS box-containing protein 1
Search

WSB1

0.96	WD repeat and SOCS box-containing protein 1

0.65	GO:0016567	protein ubiquitination
0.59	GO:0035556	intracellular signal transduction
0.35	GO:0043687	post-translational protein modification

0.37	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0005515	protein binding

0.44

GO:0005622

intracellular

0.37

GO:0004842

tr|Q7T2F7|Q7T2F7_DANRE
Calcineurin-like EF-hand protein 1
Search

CHP1

0.54	Calcium-binding protein CHP

0.56	GO:0032417	positive regulation of sodium:proton antiporter activity
0.55	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade
0.53	GO:0042308	negative regulation of protein import into nucleus
0.52	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.52	GO:0051453	regulation of intracellular pH
0.51	GO:0010923	negative regulation of phosphatase activity
0.51	GO:1901214	regulation of neuron death
0.42	GO:0060050	positive regulation of protein glycosylation
0.42	GO:0031953	negative regulation of protein autophosphorylation
0.41	GO:0006611	protein export from nucleus

0.70	GO:0005509	calcium ion binding
0.53	GO:0048306	calcium-dependent protein binding
0.40	GO:0004860	protein kinase inhibitor activity
0.39	GO:0019900	kinase binding
0.39	GO:0008017	microtubule binding
0.35	GO:0005215	transporter activity
0.35	GO:0015459	potassium channel regulator activity
0.32	GO:0004930	G-protein coupled receptor activity

0.41	GO:0005886	plasma membrane
0.40	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.39	GO:0030133	transport vesicle
0.39	GO:0000139	Golgi membrane
0.38	GO:0015630	microtubule cytoskeleton
0.38	GO:0005783	endoplasmic reticulum
0.37	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome

tr|Q7T2G0|Q7T2G0_DANRE
Tetraspanin
Search

TSPAN12

0.60	Tetraspanin

0.60	GO:0010842	retina layer formation
0.57	GO:0045765	regulation of angiogenesis
0.52	GO:0007166	cell surface receptor signaling pathway
0.41	GO:0001525	angiogenesis

0.43	GO:0042813	Wnt-activated receptor activity
0.33	GO:0005515	protein binding

0.50

GO:0005887

integral component of plasma membrane

sp|Q7T2G1|I2B2B_DANRE
Interferon regulatory factor 2-binding protein 2-B
Search

0.88	Interferon regulatory factor 2 binding protein like

0.52	GO:0097659	nucleic acid-templated transcription
0.51	GO:1903506	regulation of nucleic acid-templated transcription
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.51	GO:0010468	regulation of gene expression
0.49	GO:0010467	gene expression
0.48	GO:0034645	cellular macromolecule biosynthetic process

0.53

GO:0046872

metal ion binding

0.57	GO:0005634	nucleus
0.42	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part

tr|Q7T2I8|Q7T2I8_DANRE
Photoreceptor associated retinol dehydrogenase type 2
Search

0.93	Photoreceptor associated retinol dehydrogenase type 2

0.84	GO:0006703	estrogen biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.45	GO:0042572	retinol metabolic process
0.43	GO:0007601	visual perception
0.41	GO:0008209	androgen metabolic process
0.35	GO:0061370	testosterone biosynthetic process
0.35	GO:0010951	negative regulation of endopeptidase activity
0.34	GO:0060348	bone development
0.34	GO:0071248	cellular response to metal ion
0.33	GO:0019290	siderophore biosynthetic process

0.83	GO:0004303	estradiol 17-beta-dehydrogenase activity
0.45	GO:0004745	retinol dehydrogenase activity
0.44	GO:0047035	testosterone dehydrogenase (NAD+) activity
0.36	GO:1903924	estradiol binding
0.35	GO:0004866	endopeptidase inhibitor activity
0.35	GO:0052650	NADP-retinol dehydrogenase activity
0.34	GO:0070401	NADP+ binding
0.34	GO:0030283	testosterone dehydrogenase [NAD(P)] activity
0.33	GO:0008667	2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity
0.33	GO:0031132	serine 3-dehydrogenase activity

0.47	GO:0005737	cytoplasm
0.35	GO:0005615	extracellular space
0.34	GO:0001750	photoreceptor outer segment
0.30	GO:0031224	intrinsic component of membrane

0.83	EC:1.1.1.62	GO:0004303
0.44	KEGG:R01836	GO:0047035

tr|Q7T2J4|Q7T2J4_DANRE
Alcohol dehydrogenase 8b
Search

0.38	Alcohol dehydrogenase Class VI

0.54	GO:0006067	ethanol metabolic process
0.53	GO:0055114	oxidation-reduction process
0.42	GO:0033859	furaldehyde metabolic process
0.41	GO:0000947	amino acid catabolic process to alcohol via Ehrlich pathway
0.41	GO:0046292	formaldehyde metabolic process
0.39	GO:0046185	aldehyde catabolic process
0.39	GO:0070887	cellular response to chemical stimulus
0.37	GO:0009636	response to toxic substance
0.37	GO:0006070	octanol metabolic process
0.37	GO:0009410	response to xenobiotic stimulus

0.62	GO:0008270	zinc ion binding
0.53	GO:0016491	oxidoreductase activity
0.39	GO:0035276	ethanol binding
0.37	GO:0005503	all-trans retinal binding
0.36	GO:0019841	retinol binding
0.34	GO:0005044	scavenger receptor activity
0.34	GO:0051287	NAD binding
0.33	GO:0042803	protein homodimerization activity

0.36	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005886	plasma membrane
0.32	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.53

GO:0016491

tr|Q7T2K9|Q7T2K9_DANRE
Secreted frizzled-related protein 1
Search

SFRP1

0.94	Secreted frizzled-related protein 1

0.73	GO:0016055	Wnt signaling pathway
0.69	GO:0007275	multicellular organism development
0.69	GO:0030510	regulation of BMP signaling pathway
0.67	GO:0030111	regulation of Wnt signaling pathway
0.56	GO:0045578	negative regulation of B cell differentiation
0.55	GO:0071504	cellular response to heparin
0.55	GO:0002009	morphogenesis of an epithelium
0.55	GO:0051224	negative regulation of protein transport
0.55	GO:0033689	negative regulation of osteoblast proliferation
0.54	GO:2000271	positive regulation of fibroblast apoptotic process

0.58	GO:0017147	Wnt-protein binding
0.53	GO:0005109	frizzled binding
0.51	GO:0008201	heparin binding
0.50	GO:0042813	Wnt-activated receptor activity
0.48	GO:0004197	cysteine-type endopeptidase activity
0.47	GO:0042802	identical protein binding
0.46	GO:0004930	G-protein coupled receptor activity
0.40	GO:0008144	drug binding

0.65	GO:0005576	extracellular region
0.48	GO:0009986	cell surface
0.45	GO:0005829	cytosol
0.34	GO:0031982	vesicle
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.48

EC:3.4.22

GO:0004197

tr|Q7T2L8|Q7T2L8_DANRE
Dual specificity protein phosphatase
Search

DUSP6

0.73	Dual specificity protein phosphatase

0.85	GO:0000188	inactivation of MAPK activity
0.72	GO:0006470	protein dephosphorylation
0.59	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.55	GO:0060420	regulation of heart growth
0.54	GO:0051409	response to nitrosative stress
0.54	GO:0042663	regulation of endodermal cell fate specification
0.53	GO:0010942	positive regulation of cell death
0.52	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway
0.51	GO:0042981	regulation of apoptotic process
0.50	GO:0009953	dorsal/ventral pattern formation

0.85	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.69	GO:0004725	protein tyrosine phosphatase activity
0.35	GO:0016301	kinase activity
0.33	GO:0005515	protein binding

0.39	GO:0005737	cytoplasm
0.33	GO:0005654	nucleoplasm

0.85

EC:3.1.3

GO:0017017

tr|Q7T2P2|Q7T2P2_DANRE
T-complex protein 1 subunit gamma
Search

CCT3

0.69	T-complex protein 1 subunit gamma

0.68	GO:0006457	protein folding
0.57	GO:1904869	regulation of protein localization to Cajal body
0.56	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.55	GO:0032212	positive regulation of telomere maintenance via telomerase
0.54	GO:1900182	positive regulation of protein localization to nucleus
0.53	GO:0046931	pore complex assembly
0.53	GO:0007339	binding of sperm to zona pellucida
0.52	GO:0050821	protein stabilization
0.50	GO:1901998	toxin transport
0.47	GO:0046671	negative regulation of retinal cell programmed cell death

0.70	GO:0051082	unfolded protein binding
0.58	GO:0044183	protein binding involved in protein folding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.34	GO:0003723	RNA binding
0.33	GO:0046983	protein dimerization activity

0.57	GO:0005832	chaperonin-containing T-complex
0.54	GO:0002199	zona pellucida receptor complex
0.51	GO:0043209	myelin sheath
0.50	GO:0044297	cell body
0.49	GO:0005874	microtubule
0.42	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|Q7T2P4|Q7T2P4_DANRE
Claudin
Search

0.68

Claudin h

0.48	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.46	GO:0003382	epithelial cell morphogenesis
0.46	GO:0070830	bicellular tight junction assembly
0.46	GO:0051291	protein heterooligomerization
0.45	GO:0061436	establishment of skin barrier
0.45	GO:0001666	response to hypoxia
0.45	GO:0070293	renal absorption
0.44	GO:0051260	protein homooligomerization
0.42	GO:1902476	chloride transmembrane transport
0.36	GO:0045471	response to ethanol

0.62	GO:0005198	structural molecule activity
0.43	GO:0042802	identical protein binding
0.42	GO:0005254	chloride channel activity
0.35	GO:0001618	virus receptor activity
0.33	GO:0004888	transmembrane signaling receptor activity

0.81	GO:0005923	bicellular tight junction
0.56	GO:0005886	plasma membrane
0.36	GO:1990794	basolateral part of cell
0.34	GO:0045177	apical part of cell
0.34	GO:0070062	extracellular exosome
0.34	GO:0005737	cytoplasm
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

sp|Q7T2P6|TIM23_DANRE
Mitochondrial import inner membrane translocase subunit Tim23
Search

TIMM23

0.86	Mitochondrial import inner membrane translocase subunit Tim23

0.66	GO:0071806	protein transmembrane transport
0.65	GO:0006886	intracellular protein transport
0.47	GO:1990542	mitochondrial transmembrane transport
0.46	GO:0072655	establishment of protein localization to mitochondrion
0.45	GO:0007005	mitochondrion organization
0.45	GO:0017038	protein import
0.36	GO:1905242	response to 3,3',5-triiodo-L-thyronine
0.35	GO:0010954	positive regulation of protein processing
0.34	GO:0090150	establishment of protein localization to membrane
0.34	GO:0007275	multicellular organism development

0.70	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
0.34	GO:0005515	protein binding

0.76	GO:0005744	mitochondrial inner membrane presequence translocase complex
0.49	GO:0031305	integral component of mitochondrial inner membrane
0.44	GO:0005758	mitochondrial intermembrane space
0.34	GO:1990351	transporter complex

tr|Q7T2P7|Q7T2P7_DANRE
Glutamine synthetase
Search

0.46	Glutamine synthetase

0.76	GO:0006542	glutamine biosynthetic process
0.48	GO:0008283	cell proliferation
0.47	GO:0009749	response to glucose
0.46	GO:0031667	response to nutrient levels
0.43	GO:0031668	cellular response to extracellular stimulus
0.41	GO:0033554	cellular response to stress
0.38	GO:0051968	positive regulation of synaptic transmission, glutamatergic
0.38	GO:0019676	ammonia assimilation cycle
0.37	GO:0032024	positive regulation of insulin secretion
0.37	GO:0050679	positive regulation of epithelial cell proliferation

0.76	GO:0004356	glutamate-ammonia ligase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0042802	identical protein binding
0.41	GO:0004351	glutamate decarboxylase activity
0.38	GO:0016595	glutamate binding
0.38	GO:0045503	dynein light chain binding
0.36	GO:0030145	manganese ion binding
0.35	GO:0000287	magnesium ion binding

0.49	GO:0097386	glial cell projection
0.47	GO:0043209	myelin sheath
0.46	GO:0044297	cell body
0.44	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.37	GO:0043679	axon terminus
0.37	GO:0005791	rough endoplasmic reticulum
0.36	GO:0036477	somatodendritic compartment
0.34	GO:0070062	extracellular exosome
0.34	GO:0043234	protein complex

0.76	EC:6.3.1.2	GO:0004356
0.76	KEGG:R00253	GO:0004356

tr|Q7T2T7|Q7T2T7_DANRE
Methyl-CpG-binding protein 2
Search

MECP2

0.82	Methyl-CpG-binding protein 2

0.77	GO:0000122	negative regulation of transcription by RNA polymerase II
0.52	GO:0007626	locomotory behavior
0.50	GO:0051960	regulation of nervous system development
0.49	GO:0045595	regulation of cell differentiation
0.49	GO:0048699	generation of neurons
0.48	GO:1905643	positive regulation of DNA methylation
0.47	GO:0090063	positive regulation of microtubule nucleation
0.47	GO:0050432	catecholamine secretion
0.46	GO:0019230	proprioception
0.46	GO:1900114	positive regulation of histone H3-K9 trimethylation

0.86	GO:0010385	double-stranded methylated DNA binding
0.49	GO:0008327	methyl-CpG binding
0.46	GO:0035197	siRNA binding
0.45	GO:0047485	protein N-terminus binding
0.44	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.43	GO:0019904	protein domain specific binding
0.42	GO:0003682	chromatin binding
0.42	GO:0003729	mRNA binding
0.41	GO:0008134	transcription factor binding
0.37	GO:0016301	kinase activity

0.61	GO:0005634	nucleus
0.48	GO:0000792	heterochromatin
0.44	GO:0000930	gamma-tubulin complex
0.43	GO:0005813	centrosome
0.43	GO:0005829	cytosol
0.43	GO:0098794	postsynapse
0.38	GO:0005739	mitochondrion
0.36	GO:0034708	methyltransferase complex
0.35	GO:0070013	intracellular organelle lumen
0.33	GO:0005615	extracellular space

0.36

GO:0016773

sp|Q7T2V2|ST1S3_DANRE
Cytosolic sulfotransferase 3
Search

0.57	Cytosolic sulfotransferase 3

0.39	GO:0006584	catecholamine metabolic process
0.39	GO:0006805	xenobiotic metabolic process
0.36	GO:0008202	steroid metabolic process
0.35	GO:0051923	sulfation
0.35	GO:0034754	cellular hormone metabolic process
0.34	GO:0006068	ethanol catabolic process
0.34	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process

0.77

GO:0008146

sulfotransferase activity

0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.77

GO:0008146

tr|Q7T2W1|Q7T2W1_DANRE
Putative uncharacterized protein YF-335
Search

0.96	Zinc finger buttonhead-related transcription factor 1

0.54	GO:0048332	mesoderm morphogenesis
0.52	GO:0036342	post-anal tail morphogenesis
0.52	GO:0003002	regionalization
0.52	GO:0048598	embryonic morphogenesis
0.51	GO:0030903	notochord development
0.50	GO:0030902	hindbrain development
0.47	GO:0016055	Wnt signaling pathway
0.46	GO:0048646	anatomical structure formation involved in morphogenesis
0.45	GO:0006357	regulation of transcription by RNA polymerase II
0.44	GO:0035108	limb morphogenesis

0.51	GO:0003676	nucleic acid binding
0.45	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0046872	metal ion binding

0.41	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|Q7T2Z9|Q7T2Z9_DANRE
Immunoglobulin-like domain-containing receptor 1a
Search

0.95	Immunoglobulin like domain containing receptor 1

0.52	GO:0090277	positive regulation of peptide hormone secretion
0.52	GO:1990830	cellular response to leukemia inhibitory factor
0.51	GO:0051260	protein homooligomerization
0.49	GO:0048513	animal organ development
0.47	GO:0048916	posterior lateral line development
0.47	GO:0006898	receptor-mediated endocytosis
0.45	GO:0030336	negative regulation of cell migration
0.44	GO:0035295	tube development
0.44	GO:1904274	tricellular tight junction assembly
0.44	GO:0061833	protein localization to tricellular tight junction

0.56	GO:0070506	high-density lipoprotein particle receptor activity
0.49	GO:0042802	identical protein binding
0.33	GO:0017129	triglyceride binding
0.33	GO:0030169	low-density lipoprotein particle binding
0.33	GO:0005504	fatty acid binding
0.32	GO:0046983	protein dimerization activity

0.57	GO:0061689	tricellular tight junction
0.43	GO:0043234	protein complex
0.42	GO:0005886	plasma membrane
0.36	GO:0005829	cytosol
0.35	GO:0034362	low-density lipoprotein particle
0.35	GO:0042627	chylomicron
0.34	GO:0034361	very-low-density lipoprotein particle
0.33	GO:0070062	extracellular exosome
0.33	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

tr|Q7T303|Q7T303_DANRE
Calponin
Search

CNN3

0.87

Calponin

0.82	GO:0031032	actomyosin structure organization
0.51	GO:0030855	epithelial cell differentiation
0.50	GO:0098609	cell-cell adhesion
0.38	GO:0032780	negative regulation of ATPase activity
0.36	GO:0006488	dolichol-linked oligosaccharide biosynthetic process

0.77	GO:0005516	calmodulin binding
0.74	GO:0003779	actin binding
0.55	GO:0098641	cadherin binding involved in cell-cell adhesion
0.38	GO:0008017	microtubule binding
0.34	GO:0030674	protein binding, bridging

0.52	GO:0005913	cell-cell adherens junction
0.48	GO:0015629	actin cytoskeleton
0.46	GO:0005829	cytosol
0.38	GO:0043197	dendritic spine
0.38	GO:0014069	postsynaptic density
0.38	GO:0043025	neuronal cell body
0.36	GO:0005925	focal adhesion
0.34	GO:0005874	microtubule

sp|Q7T308|RN168_DANRE
E3 ubiquitin-protein ligase rnf168
Search

RNF168

0.64	E3 ubiquitin-protein ligase rnf168

0.73	GO:0033522	histone H2A ubiquitination
0.71	GO:0045739	positive regulation of DNA repair
0.69	GO:0010212	response to ionizing radiation
0.69	GO:0006302	double-strand break repair
0.56	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter
0.55	GO:0070534	protein K63-linked ubiquitination
0.54	GO:0010390	histone monoubiquitination
0.49	GO:0006511	ubiquitin-dependent protein catabolic process
0.46	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response
0.45	GO:0002312	B cell activation involved in immune response

0.68	GO:0043130	ubiquitin binding
0.67	GO:0004842	ubiquitin-protein transferase activity
0.67	GO:0042393	histone binding
0.65	GO:0003682	chromatin binding
0.56	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding
0.50	GO:0016874	ligase activity
0.50	GO:0046872	metal ion binding
0.47	GO:0044877	macromolecular complex binding
0.34	GO:0031624	ubiquitin conjugating enzyme binding
0.33	GO:0003924	GTPase activity

0.64	GO:0000151	ubiquitin ligase complex
0.54	GO:0035861	site of double-strand break
0.53	GO:0005634	nucleus
0.45	GO:0070013	intracellular organelle lumen
0.45	GO:0005829	cytosol
0.41	GO:0043234	protein complex
0.35	GO:1990391	DNA repair complex
0.32	GO:0010494	cytoplasmic stress granule
0.32	GO:0033290	eukaryotic 48S preinitiation complex
0.32	GO:0015935	small ribosomal subunit

0.50	EC:6	GO:0016874
0.67	KEGG:R03876	GO:0004842

tr|Q7T309|Q7T309_DANRE
Serpin peptidase inhibitor, clade B (Ovalbumin), member 1, like 3
Search

0.78	Leukocyte elastase inhibitor A

0.66	GO:0010951	negative regulation of endopeptidase activity
0.42	GO:0042270	protection from natural killer cell mediated cytotoxicity
0.42	GO:0002444	myeloid leukocyte mediated immunity
0.41	GO:0033668	negative regulation by symbiont of host apoptotic process
0.41	GO:0071391	cellular response to estrogen stimulus
0.40	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.39	GO:0043066	negative regulation of apoptotic process
0.39	GO:0006915	apoptotic process
0.39	GO:0006955	immune response
0.39	GO:0009617	response to bacterium

0.68	GO:0004867	serine-type endopeptidase inhibitor activity
0.42	GO:0002020	protease binding
0.41	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.34	GO:0004601	peroxidase activity
0.33	GO:0008233	peptidase activity

0.73	GO:0005615	extracellular space
0.38	GO:0005794	Golgi apparatus
0.38	GO:0005829	cytosol
0.38	GO:0005654	nucleoplasm
0.37	GO:0097180	serine protease inhibitor complex
0.37	GO:0031012	extracellular matrix
0.35	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0070821	tertiary granule membrane
0.34	GO:1903561	extracellular vesicle
0.32	GO:0005886	plasma membrane

0.34	EC:1.11.1.7	GO:0004601
0.34	KEGG:R03532	GO:0004601

sp|Q7T310|PIGM_DANRE
GPI mannosyltransferase 1
Search

PIGM

0.82	Phosphatidylinositol glycan anchor biosynthesis class M

0.78	GO:0006506	GPI anchor biosynthetic process
0.44	GO:0031505	fungal-type cell wall organization
0.44	GO:0097502	mannosylation
0.34	GO:0036065	fucosylation
0.33	GO:0043413	macromolecule glycosylation
0.33	GO:0009101	glycoprotein biosynthetic process
0.33	GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine
0.32	GO:0006886	intracellular protein transport
0.32	GO:0016192	vesicle-mediated transport
0.32	GO:0032259	methylation

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.33	GO:0004164	diphthine synthase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:1990529	glycosylphosphatidylinositol-mannosyltransferase I complex
0.40	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0032580	Golgi cisterna membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0016758

sp|Q7T312|CCD25_DANRE
Coiled-coil domain-containing protein 25
Search

CCDC25

0.90	Coiled-coil domain-containing protein 25

0.41	GO:0043043	peptide biosynthetic process
0.40	GO:0044267	cellular protein metabolic process
0.39	GO:0010467	gene expression
0.38	GO:0009059	macromolecule biosynthetic process

0.45	GO:0005515	protein binding
0.43	GO:0003735	structural constituent of ribosome

0.63	GO:0070062	extracellular exosome
0.42	GO:0005840	ribosome

tr|Q7T314|Q7T314_DANRE
Translocase of outer mitochondrial membrane 40 homolog (Yeast)
Search

TOMM40

0.89	Translocase of outer mitochondrial membrane 40

0.82	GO:0030150	protein import into mitochondrial matrix
0.36	GO:0006811	ion transport
0.35	GO:0051204	protein insertion into mitochondrial membrane
0.34	GO:0016236	macroautophagy
0.34	GO:0043065	positive regulation of apoptotic process

0.74	GO:0008320	protein transmembrane transporter activity
0.39	GO:0070678	preprotein binding
0.39	GO:0015288	porin activity
0.37	GO:0030943	mitochondrion targeting sequence binding
0.34	GO:0005261	cation channel activity

0.78	GO:0005741	mitochondrial outer membrane
0.50	GO:0098798	mitochondrial protein complex
0.50	GO:0044455	mitochondrial membrane part
0.45	GO:0098796	membrane protein complex
0.44	GO:0031301	integral component of organelle membrane
0.43	GO:0005829	cytosol
0.41	GO:0005743	mitochondrial inner membrane
0.36	GO:0070062	extracellular exosome

sp|Q7T316|TM231_DANRE
Transmembrane protein 231
Search

TMEM231

0.97	Transmembrane protein 231

0.58	GO:0007224	smoothened signaling pathway
0.57	GO:0060563	neuroepithelial cell differentiation
0.57	GO:0042733	embryonic digit morphogenesis
0.57	GO:0060271	cilium assembly
0.55	GO:0043010	camera-type eye development
0.54	GO:0001944	vasculature development
0.54	GO:0032880	regulation of protein localization
0.52	GO:0001701	in utero embryonic development
0.34	GO:0006430	lysyl-tRNA aminoacylation
0.33	GO:0006396	RNA processing

0.37	GO:0008146	sulfotransferase activity
0.35	GO:0005515	protein binding
0.34	GO:0004000	adenosine deaminase activity
0.34	GO:0004824	lysine-tRNA ligase activity
0.32	GO:0003723	RNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0060170	ciliary membrane
0.59	GO:0036038	MKS complex
0.33	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0008146

tr|Q7T319|Q7T319_DANRE
Transcription elongation factor 1 homolog
Search

ELOF1

0.70	Transcription elongation factor 1 homolog

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0006414	translational elongation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.46	GO:0006338	chromatin remodeling
0.45	GO:0051254	positive regulation of RNA metabolic process
0.44	GO:0010557	positive regulation of macromolecule biosynthetic process
0.44	GO:0031328	positive regulation of cellular biosynthetic process
0.34	GO:0007166	cell surface receptor signaling pathway

0.58	GO:0003746	translation elongation factor activity
0.54	GO:0046872	metal ion binding
0.49	GO:0000993	RNA polymerase II core binding
0.34	GO:0004930	G-protein coupled receptor activity
0.32	GO:0004386	helicase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.43	GO:0031974	membrane-enclosed lumen
0.40	GO:0043234	protein complex
0.39	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q7T320|GORAB_DANRE
RAB6-interacting golgin
Search

GORAB

0.97	RAB6-interacting golgin

0.86	GO:1901622	positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.80	GO:1905515	non-motile cilium assembly
0.80	GO:0031069	hair follicle morphogenesis
0.36	GO:0016310	phosphorylation
0.35	GO:0051639	actin filament network formation
0.35	GO:0051764	actin crosslink formation
0.35	GO:0051017	actin filament bundle assembly
0.33	GO:2000142	regulation of DNA-templated transcription, initiation
0.33	GO:0006352	DNA-templated transcription, initiation

0.38	GO:0005515	protein binding
0.36	GO:0016301	kinase activity
0.34	GO:0044877	macromolecular complex binding
0.33	GO:0016987	bacterial sigma factor activity
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003677	DNA binding

0.70	GO:0005794	Golgi apparatus
0.69	GO:0005730	nucleolus
0.66	GO:0005654	nucleoplasm
0.65	GO:0005829	cytosol
0.35	GO:0032432	actin filament bundle
0.35	GO:0005884	actin filament
0.30	GO:0031224	intrinsic component of membrane

sp|Q7T321|KCMF1_DANRE
E3 ubiquitin-protein ligase KCMF1
Search

KCMF1

0.93	Z-linked potassium channel modulatory factor 1

0.35	GO:0043312	neutrophil degranulation
0.34	GO:0016567	protein ubiquitination

0.61	GO:0008270	zinc ion binding
0.52	GO:0016874	ligase activity
0.50	GO:0003676	nucleic acid binding
0.34	GO:0016740	transferase activity
0.33	GO:0140096	catalytic activity, acting on a protein

0.46	GO:0005829	cytosol
0.35	GO:1904813	ficolin-1-rich granule lumen
0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.52

GO:0016874

sp|Q7T322|NAA35_DANRE
N-alpha-acetyltransferase 35, NatC auxiliary subunit
Search

NAA35

0.96	N-alpha-acetyltransferase 35, NatC auxiliary subunit

0.68	GO:0048659	smooth muscle cell proliferation
0.59	GO:0043066	negative regulation of apoptotic process
0.51	GO:0006474	N-terminal protein amino acid acetylation
0.37	GO:0001756	somitogenesis
0.36	GO:0048514	blood vessel morphogenesis
0.36	GO:0032006	regulation of TOR signaling
0.36	GO:0008284	positive regulation of cell proliferation

0.52	GO:0004596	peptide alpha-N-acetyltransferase activity
0.35	GO:0005515	protein binding

0.66	GO:0031417	NatC complex
0.62	GO:0005844	polysome

0.52

EC:2.3.1.88

GO:0004596

sp|Q7T326|CISD2_DANRE
CDGSH iron-sulfur domain-containing protein 2
Search

CISD2

0.97	CDGSH iron-sulfur domain-containing protein 2

0.56	GO:0000422	autophagy of mitochondrion
0.55	GO:0010259	multicellular organism aging
0.51	GO:0010506	regulation of autophagy

0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.52	GO:0042803	protein homodimerization activity
0.37	GO:0046872	metal ion binding
0.34	GO:0003723	RNA binding

0.56	GO:0043231	intracellular membrane-bounded organelle
0.52	GO:0031968	organelle outer membrane
0.50	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.48	GO:0031984	organelle subcompartment
0.42	GO:0043234	protein complex
0.42	GO:0044444	cytoplasmic part
0.30	GO:0016021	integral component of membrane

tr|Q7T328|Q7T328_DANRE
Integral membrane protein 2Bb
Search

ITM2B

0.96	Integral membrane protein 2Bb

0.59	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process
0.43	GO:0007399	nervous system development
0.39	GO:0006915	apoptotic process
0.38	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.37	GO:0008285	negative regulation of cell proliferation
0.36	GO:0045892	negative regulation of transcription, DNA-templated
0.36	GO:0038034	signal transduction in absence of ligand
0.36	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0007166	cell surface receptor signaling pathway
0.32	GO:0044267	cellular protein metabolic process

0.56	GO:0001540	amyloid-beta binding
0.40	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0008134	transcription factor binding

0.50	GO:0030660	Golgi-associated vesicle membrane
0.50	GO:0031301	integral component of organelle membrane
0.50	GO:0005615	extracellular space
0.49	GO:0005794	Golgi apparatus
0.45	GO:1903561	extracellular vesicle
0.42	GO:0005886	plasma membrane
0.41	GO:0010008	endosome membrane
0.39	GO:0035189	Rb-E2F complex
0.39	GO:0031984	organelle subcompartment

sp|Q7T330|SPOP_DANRE
Speckle-type POZ protein
Search

SPOP

0.90	Speckle type BTB/POZ protein

0.86	GO:2000676	positive regulation of type B pancreatic cell apoptotic process
0.85	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.79	GO:0043433	negative regulation of DNA binding transcription factor activity
0.79	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.78	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.76	GO:0042593	glucose homeostasis
0.74	GO:0000122	negative regulation of transcription by RNA polymerase II
0.56	GO:0051246	regulation of protein metabolic process

0.79	GO:0001085	RNA polymerase II transcription factor binding
0.76	GO:0031625	ubiquitin protein ligase binding

0.83	GO:0031463	Cul3-RING ubiquitin ligase complex
0.76	GO:0016607	nuclear speck
0.60	GO:0019005	SCF ubiquitin ligase complex
0.41	GO:0005737	cytoplasm

tr|Q7T334|Q7T334_DANRE
Malate dehydrogenase
Search

MDH2

0.46	Malate dehydrogenase, mitochondrial

0.78	GO:0006108	malate metabolic process
0.70	GO:0006099	tricarboxylic acid cycle
0.60	GO:0005975	carbohydrate metabolic process
0.51	GO:0006475	internal protein amino acid acetylation
0.39	GO:0006734	NADH metabolic process
0.38	GO:0006107	oxaloacetate metabolic process
0.33	GO:0044283	small molecule biosynthetic process
0.32	GO:1901576	organic substance biosynthetic process

0.79	GO:0030060	L-malate dehydrogenase activity
0.39	GO:0046554	malate dehydrogenase (NADP+) activity
0.39	GO:0042803	protein homodimerization activity
0.39	GO:0043621	protein self-association
0.34	GO:0051087	chaperone binding
0.33	GO:0003723	RNA binding

0.51	GO:0043209	myelin sheath
0.44	GO:0044429	mitochondrial part
0.43	GO:0019866	organelle inner membrane
0.39	GO:0031974	membrane-enclosed lumen
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus

0.79	EC:1.1.1.37	GO:0030060
0.39	KEGG:R00343	GO:0046554

tr|Q7T337|Q7T337_DANRE
Fructose-1,6-bisphosphatase 1b
Search

0.51	Acipenser baerii fructose 1,6-bisphosphatase mRNA

0.68	GO:0016311	dephosphorylation
0.60	GO:0005975	carbohydrate metabolic process
0.55	GO:0071286	cellular response to magnesium ion
0.54	GO:0045820	negative regulation of glycolytic process
0.52	GO:0006002	fructose 6-phosphate metabolic process
0.52	GO:0051289	protein homotetramerization
0.52	GO:0006111	regulation of gluconeogenesis
0.52	GO:0046580	negative regulation of Ras protein signal transduction
0.51	GO:0030308	negative regulation of cell growth
0.50	GO:0035690	cellular response to drug

0.79	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity
0.52	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.50	GO:0042802	identical protein binding
0.50	GO:0016208	AMP binding
0.40	GO:0048029	monosaccharide binding
0.40	GO:0046872	metal ion binding
0.35	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity

0.44	GO:0005634	nucleus
0.44	GO:0005829	cytosol
0.39	GO:0043233	organelle lumen
0.37	GO:0044446	intracellular organelle part
0.37	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0030018	Z disc
0.34	GO:0030054	cell junction
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:3.1.3.11

GO:0042132

sp|Q7T338|FGOP2_DANRE
FGFR1 oncogene partner 2 homolog
Search

FGFR1OP2

0.96	FGFR1 oncogene partner 2 homolog

0.76	GO:0042060	wound healing
0.38	GO:0018108	peptidyl-tyrosine phosphorylation

0.72	GO:0042803	protein homodimerization activity
0.38	GO:0004713	protein tyrosine kinase activity

0.40

GO:0005737

cytoplasm

0.38

GO:0004713

sp|Q7T339|CHMP5_DANRE
Charged multivesicular body protein 5
Search

CHMP5

0.87	Charged multivesicular body protein 5

0.76	GO:0007034	vacuolar transport
0.53	GO:1901673	regulation of mitotic spindle assembly
0.53	GO:0000920	cell separation after cytokinesis
0.52	GO:0007080	mitotic metaphase plate congression
0.52	GO:0010824	regulation of centrosome duplication
0.51	GO:0006997	nucleus organization
0.50	GO:0071985	multivesicular body sorting pathway
0.49	GO:0001919	regulation of receptor recycling
0.48	GO:0007040	lysosome organization
0.47	GO:0046755	viral budding

0.51

GO:0045296

cadherin binding

0.46	GO:0005829	cytosol
0.40	GO:0010008	endosome membrane
0.40	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome

tr|Q7T340|Q7T340_DANRE
Developmentally regulated GTP binding protein 1
Search

DRG1

0.89	Developmentally-regulated GTP-binding protein 1

0.33	GO:0007275	multicellular organism development
0.33	GO:0001522	pseudouridine synthesis
0.32	GO:0006351	transcription, DNA-templated

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0042802	identical protein binding
0.34	GO:0008134	transcription factor binding
0.33	GO:0009982	pseudouridine synthase activity
0.32	GO:0003723	RNA binding

0.51	GO:0005844	polysome
0.49	GO:0016604	nuclear body
0.45	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:5.4.99.12

GO:0009982

sp|Q7T346|DDIT4_DANRE
DNA damage-inducible transcript 4 protein
Search

DDIT4

0.97	DNA-damage-inducible transcript 4

0.71	GO:0009968	negative regulation of signal transduction
0.60	GO:0045820	negative regulation of glycolytic process
0.59	GO:0071549	cellular response to dexamethasone stimulus
0.58	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.55	GO:0001666	response to hypoxia
0.54	GO:0032006	regulation of TOR signaling
0.52	GO:0051607	defense response to virus
0.51	GO:0043241	protein complex disassembly
0.51	GO:0072593	reactive oxygen species metabolic process
0.47	GO:0009953	dorsal/ventral pattern formation

0.59

GO:0071889

14-3-3 protein binding

0.48	GO:0005829	cytosol
0.46	GO:0005739	mitochondrion

sp|Q7T347|UFSP2_DANRE
Ufm1-specific protease 2
Search

UFSP2

0.96	Ufm1-specific peptidase 2

0.59	GO:0033146	regulation of intracellular estrogen receptor signaling pathway
0.58	GO:0006508	proteolysis

0.65	GO:0071567	UFM1 hydrolase activity
0.54	GO:0016790	thiolester hydrolase activity
0.33	GO:0005515	protein binding

0.51	GO:0005783	endoplasmic reticulum
0.47	GO:0005634	nucleus

0.54

EC:3.1.2

GO:0016790

tr|Q7T351|Q7T351_DANRE
Activating transcription factor 1
Search

ATF1

0.88	Cyclic AMP-responsive element-binding protein 1

0.68	GO:0006357	regulation of transcription by RNA polymerase II
0.49	GO:0006366	transcription by RNA polymerase II
0.48	GO:0045893	positive regulation of transcription, DNA-templated
0.39	GO:0032025	response to cobalt ion
0.38	GO:0045740	positive regulation of DNA replication
0.37	GO:0010976	positive regulation of neuron projection development
0.37	GO:0014070	response to organic cyclic compound
0.36	GO:0043623	cellular protein complex assembly

0.72	GO:0046982	protein heterodimerization activity
0.63	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0042802	identical protein binding
0.48	GO:0003690	double-stranded DNA binding
0.36	GO:0032403	protein complex binding

0.60	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part

sp|Q7T352|TM263_DANRE
Transmembrane protein 263
Search

TMEM263

0.63	Transmembrane domain-containing protein (Fragment)

0.36	GO:0043631	RNA polyadenylation
0.36	GO:0031123	RNA 3'-end processing

0.34	GO:0016779	nucleotidyltransferase activity
0.34	GO:0003723	RNA binding

0.30

GO:0031224

intrinsic component of membrane

0.34

GO:0016779

tr|Q7T355|Q7T355_DANRE
Ariadne homolog 2 (Drosophila)
Search

ARIH2

0.58	RING-type E3 ubiquitin transferase

0.72	GO:0016567	protein ubiquitination
0.53	GO:0071425	hematopoietic stem cell proliferation
0.52	GO:1903955	positive regulation of protein targeting to mitochondrion
0.51	GO:0048588	developmental cell growth
0.50	GO:0006511	ubiquitin-dependent protein catabolic process
0.47	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.33	GO:0055114	oxidation-reduction process

0.73	GO:0004842	ubiquitin-protein transferase activity
0.55	GO:0031624	ubiquitin conjugating enzyme binding
0.54	GO:0046872	metal ion binding
0.51	GO:0016874	ligase activity
0.45	GO:0061659	ubiquitin-like protein ligase activity
0.35	GO:0031418	L-ascorbic acid binding
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0003676	nucleic acid binding

0.53	GO:0031466	Cul5-RING ubiquitin ligase complex
0.46	GO:0005654	nucleoplasm
0.38	GO:0005737	cytoplasm

0.51	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

sp|Q7T356|143BB_DANRE
14-3-3 protein beta/alpha-B
Search

YWHAB

0.94	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta

0.56	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway
0.55	GO:0051220	cytoplasmic sequestering of protein
0.53	GO:0035308	negative regulation of protein dephosphorylation
0.49	GO:0043085	positive regulation of catalytic activity
0.48	GO:0006605	protein targeting
0.39	GO:0051291	protein heterooligomerization
0.38	GO:0055114	oxidation-reduction process
0.37	GO:0045892	negative regulation of transcription, DNA-templated
0.36	GO:0006911	phagocytosis, engulfment
0.35	GO:0001558	regulation of cell growth

0.77	GO:0019904	protein domain specific binding
0.56	GO:0050815	phosphoserine residue binding
0.54	GO:0042826	histone deacetylase binding
0.53	GO:0045296	cadherin binding
0.49	GO:0042802	identical protein binding
0.43	GO:0004497	monooxygenase activity
0.39	GO:0008022	protein C-terminus binding
0.39	GO:0003714	transcription corepressor activity
0.38	GO:0032403	protein complex binding
0.36	GO:0005520	insulin-like growth factor binding

0.52	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005829	cytosol
0.40	GO:0042470	melanosome
0.39	GO:0017053	transcriptional repressor complex
0.36	GO:0005925	focal adhesion
0.36	GO:0005576	extracellular region
0.35	GO:0005634	nucleus
0.35	GO:0030659	cytoplasmic vesicle membrane
0.35	GO:0043234	protein complex
0.33	GO:0005739	mitochondrion

tr|Q7T361|Q7T361_DANRE
Stx8 protein
Search

STX8

0.93	Putative syntaxin-8 protein kinase regulator

0.61	GO:0045022	early endosome to late endosome transport
0.60	GO:1903076	regulation of protein localization to plasma membrane
0.59	GO:0071346	cellular response to interferon-gamma
0.52	GO:0006906	vesicle fusion
0.50	GO:0048278	vesicle docking
0.49	GO:0065009	regulation of molecular function
0.46	GO:0006886	intracellular protein transport
0.40	GO:0008333	endosome to lysosome transport
0.33	GO:0016310	phosphorylation

0.65	GO:0000149	SNARE binding
0.63	GO:0019869	chloride channel inhibitor activity
0.56	GO:0031625	ubiquitin protein ligase binding
0.51	GO:0005484	SNAP receptor activity
0.34	GO:0016301	kinase activity

0.58	GO:0055037	recycling endosome
0.58	GO:0045335	phagocytic vesicle
0.57	GO:0005770	late endosome
0.57	GO:0005769	early endosome
0.57	GO:0005802	trans-Golgi network
0.56	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0031201	SNARE complex
0.51	GO:0005829	cytosol
0.39	GO:0005765	lysosomal membrane
0.39	GO:0010008	endosome membrane

sp|Q7T364|TPL2B_DANRE
Tumor necrosis factor, alpha-induced protein 8-like protein 2 B
Search

0.95	TNF alpha induced protein 8 like 2

0.74	GO:0042981	regulation of apoptotic process
0.51	GO:0050868	negative regulation of T cell activation
0.51	GO:0050728	negative regulation of inflammatory response
0.43	GO:0045087	innate immune response
0.40	GO:1902531	regulation of intracellular signal transduction
0.39	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
0.38	GO:0009968	negative regulation of signal transduction
0.37	GO:0048017	inositol lipid-mediated signaling
0.37	GO:0006869	lipid transport
0.37	GO:0001934	positive regulation of protein phosphorylation

0.39	GO:0008526	phosphatidylinositol transporter activity
0.37	GO:0035091	phosphatidylinositol binding
0.34	GO:0005515	protein binding
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0004497	monooxygenase activity
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding

0.39	GO:0005737	cytoplasm
0.36	GO:0005654	nucleoplasm
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

EC:1.14

GO:0016705

tr|Q7T366|Q7T366_DANRE
Golgi SNAP receptor complex member 2
Search

GOSR2

0.93	Golgi SNAP receptor complex member 2

0.67	GO:0016192	vesicle-mediated transport
0.67	GO:0061025	membrane fusion
0.53	GO:0015031	protein transport
0.42	GO:0072666	establishment of protein localization to vacuole
0.42	GO:0048284	organelle fusion
0.41	GO:0016482	cytosolic transport
0.41	GO:0016050	vesicle organization
0.41	GO:0007034	vacuolar transport
0.41	GO:0016197	endosomal transport
0.36	GO:0036498	IRE1-mediated unfolded protein response

0.78	GO:0005484	SNAP receptor activity
0.42	GO:0000149	SNARE binding

0.69	GO:0005794	Golgi apparatus
0.42	GO:0031902	late endosome membrane
0.42	GO:0031201	SNARE complex
0.41	GO:0012507	ER to Golgi transport vesicle membrane
0.41	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0005829	cytosol
0.35	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.30	GO:0016021	integral component of membrane

tr|Q7T368|Q7T368_DANRE
Pyruvate dehydrogenase (Lipoamide) beta
Search

PDHB

0.55	Mitochondrial pyruvate dehydrogenase e1 component subunit beta

0.57	GO:0006086	acetyl-CoA biosynthetic process from pyruvate
0.49	GO:0006099	tricarboxylic acid cycle
0.46	GO:0043473	pigmentation
0.40	GO:0019362	pyridine nucleotide metabolic process
0.40	GO:0006757	ATP generation from ADP
0.39	GO:0005975	carbohydrate metabolic process
0.38	GO:1901575	organic substance catabolic process
0.36	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate
0.33	GO:0006508	proteolysis

0.60	GO:0004738	pyruvate dehydrogenase activity
0.49	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.45	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
0.34	GO:0008234	cysteine-type peptidase activity
0.33	GO:0005515	protein binding

0.54	GO:0045254	pyruvate dehydrogenase complex
0.50	GO:0031974	membrane-enclosed lumen
0.47	GO:0044428	nuclear part
0.46	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome

0.49

GO:0016620

tr|Q7T369|Q7T369_DANRE
WBP2 N-terminal-like
Search

WBP2

0.93	WW domain-binding protein 2

0.75	GO:0035038	female pronucleus assembly
0.75	GO:0035039	male pronucleus assembly
0.73	GO:0007343	egg activation
0.69	GO:0071391	cellular response to estrogen stimulus
0.68	GO:0045815	positive regulation of gene expression, epigenetic
0.61	GO:0006366	transcription by RNA polymerase II
0.61	GO:0045944	positive regulation of transcription by RNA polymerase II
0.52	GO:0071442	positive regulation of histone H3-K14 acetylation
0.51	GO:0050847	progesterone receptor signaling pathway
0.51	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway

0.73	GO:0050699	WW domain binding
0.68	GO:0001105	RNA polymerase II transcription coactivator activity
0.50	GO:0030331	estrogen receptor binding
0.49	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.48	GO:0031490	chromatin DNA binding
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008270	zinc ion binding

0.75	GO:0033011	perinuclear theca
0.61	GO:0000790	nuclear chromatin
0.30	GO:0031224	intrinsic component of membrane

sp|Q7T370|CDV3_DANRE
Protein CDV3 homolog
Search

CDV3

0.97	Carnitine deficiency-associated gene expressed in ventricle 3

0.41	GO:0045104	intermediate filament cytoskeleton organization
0.40	GO:0043525	positive regulation of neuron apoptotic process
0.40	GO:0008283	cell proliferation
0.39	GO:0050796	regulation of insulin secretion
0.38	GO:0008285	negative regulation of cell proliferation
0.38	GO:0008284	positive regulation of cell proliferation
0.38	GO:0043066	negative regulation of apoptotic process
0.38	GO:0000122	negative regulation of transcription by RNA polymerase II
0.38	GO:0045595	regulation of cell differentiation
0.38	GO:0045944	positive regulation of transcription by RNA polymerase II

0.37	GO:0046983	protein dimerization activity
0.36	GO:0005198	structural molecule activity
0.36	GO:0043565	sequence-specific DNA binding
0.36	GO:0003700	DNA binding transcription factor activity

0.59	GO:0005829	cytosol
0.50	GO:0005886	plasma membrane
0.40	GO:0005882	intermediate filament
0.36	GO:0005634	nucleus

tr|Q7T372|Q7T372_DANRE
Actin related protein 2/3 complex, subunit 1B
Search

ARPC1B

0.75	Actin-related protein 2/3 complex subunit

0.80	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.39	GO:0032355	response to estradiol
0.39	GO:0043627	response to estrogen
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.35	GO:0048013	ephrin receptor signaling pathway

0.70	GO:0003779	actin binding
0.51	GO:0032403	protein complex binding
0.50	GO:0005200	structural constituent of cytoskeleton

0.79	GO:0005885	Arp2/3 protein complex
0.47	GO:0005737	cytoplasm
0.44	GO:0036195	muscle cell projection membrane
0.41	GO:0036284	tubulobulbar complex
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome

tr|Q7T374|Q7T374_DANRE
Protein kinase, cAMP-dependent, catalytic, beta a
Search

PRKACB

0.87	cAMP-dependent protein kinase catalytic subunit beta

0.62	GO:0006468	protein phosphorylation
0.52	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.50	GO:0001843	neural tube closure
0.50	GO:0070613	regulation of protein processing
0.39	GO:0097338	response to clozapine
0.38	GO:0051447	negative regulation of meiotic cell cycle
0.35	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway

0.69	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0031625	ubiquitin protein ligase binding
0.44	GO:0060089	molecular transducer activity
0.43	GO:0000287	magnesium ion binding
0.36	GO:0034237	protein kinase A regulatory subunit binding

0.50	GO:0097546	ciliary base
0.50	GO:0045171	intercellular bridge
0.47	GO:0005813	centrosome
0.44	GO:0005829	cytosol
0.37	GO:0005952	cAMP-dependent protein kinase complex
0.37	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005634	nucleus
0.35	GO:0070062	extracellular exosome
0.34	GO:0005886	plasma membrane

0.69

GO:0004674

tr|Q7T376|Q7T376_DANRE
Tetraspanin
Search

0.63	Tetraspanin

0.43

GO:0007166

cell surface receptor signaling pathway

0.42

GO:0005887

integral component of plasma membrane

sp|Q7T381|BOKB_DANRE
Bcl-2-related ovarian killer protein homolog B
Search

BOK

0.97	Bcl-2-related ovarian killer protein homolog B

0.74	GO:0042981	regulation of apoptotic process
0.58	GO:0006915	apoptotic process
0.56	GO:0051902	negative regulation of mitochondrial depolarization
0.55	GO:1901382	regulation of chorionic trophoblast cell proliferation
0.55	GO:1903899	positive regulation of PERK-mediated unfolded protein response
0.55	GO:0060546	negative regulation of necroptotic process
0.53	GO:0010823	negative regulation of mitochondrion organization
0.53	GO:0070997	neuron death
0.53	GO:0046902	regulation of mitochondrial membrane permeability
0.52	GO:2001056	positive regulation of cysteine-type endopeptidase activity

0.50	GO:0042803	protein homodimerization activity
0.50	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0005102	receptor binding
0.45	GO:0046982	protein heterodimerization activity
0.41	GO:0051400	BH domain binding

0.55	GO:0033106	cis-Golgi network membrane
0.53	GO:0032588	trans-Golgi network membrane
0.53	GO:0055038	recycling endosome membrane
0.52	GO:0031901	early endosome membrane
0.47	GO:0005789	endoplasmic reticulum membrane
0.45	GO:0005741	mitochondrial outer membrane
0.43	GO:0019866	organelle inner membrane
0.43	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|Q7T382|Q7T382_DANRE
Transmembrane protein 134
Search

TMEM134

0.97	Transmembrane protein 134

0.34

GO:0005515

protein binding

0.51	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0044425	membrane part

tr|Q7T383|Q7T383_DANRE
Rala protein
Search

RALA

0.96	RAS like proto-oncogene A

0.80	GO:0007265	Ras protein signal transduction
0.55	GO:0051665	membrane raft localization
0.53	GO:0051491	positive regulation of filopodium assembly
0.51	GO:0017157	regulation of exocytosis
0.51	GO:0001843	neural tube closure
0.49	GO:0031532	actin cytoskeleton reorganization
0.40	GO:0071360	cellular response to exogenous dsRNA
0.40	GO:2000786	positive regulation of autophagosome assembly
0.39	GO:0032092	positive regulation of protein binding
0.39	GO:0032091	negative regulation of protein binding

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.56	GO:0031755	Edg-2 lysophosphatidic acid receptor binding
0.54	GO:0051117	ATPase binding
0.54	GO:0019003	GDP binding
0.52	GO:0017022	myosin binding
0.51	GO:0031625	ubiquitin protein ligase binding
0.34	GO:0030165	PDZ domain binding
0.34	GO:0004713	protein tyrosine kinase activity

0.54	GO:0005886	plasma membrane
0.53	GO:0097610	cell surface furrow
0.51	GO:0032155	cell division site part
0.51	GO:0030139	endocytic vesicle
0.50	GO:0043209	myelin sheath
0.43	GO:0030496	midbody
0.39	GO:0005776	autophagosome
0.38	GO:0000145	exocyst
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome

0.34

GO:0004713

sp|Q7T384|SC5AC_DANRE
Sodium-coupled monocarboxylate transporter 2
Search

SLC5A12

0.92	Solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12

0.64

GO:0035873

lactate transmembrane transport

0.64

GO:0015129

lactate transmembrane transporter activity

0.39	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q7T385|VTC1A_DANRE
V-type proton ATPase subunit C 1-A
Search

ATP6V1C1

0.67	V-type proton ATPase subunit C

0.75	GO:0015991	ATP hydrolysis coupled proton transport
0.35	GO:0090383	phagosome acidification
0.35	GO:0033572	transferrin transport
0.35	GO:0008286	insulin receptor signaling pathway
0.34	GO:0016241	regulation of macroautophagy

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.54	GO:0036442	proton-exporting ATPase activity
0.52	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.44	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.33	GO:0005515	protein binding

0.80	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.47	GO:0005765	lysosomal membrane
0.47	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.42	GO:0005886	plasma membrane
0.38	GO:0045177	apical part of cell
0.37	GO:0031410	cytoplasmic vesicle
0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|Q7T386|Q7T386_DANRE
Ankyrin repeat and SOCS box-containing 8
Search

ASB8

0.83	Ankyrin repeat and SOCS box-containing 8

0.65	GO:0016567	protein ubiquitination
0.59	GO:0035556	intracellular signal transduction
0.33	GO:0043687	post-translational protein modification
0.33	GO:0009116	nucleoside metabolic process
0.32	GO:0030001	metal ion transport
0.31	GO:0055085	transmembrane transport

0.32	GO:0046873	metal ion transmembrane transporter activity
0.30	GO:0003824	catalytic activity

0.44	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

tr|Q7T387|Q7T387_DANRE
Abhydrolase domain-containing 14B
Search

ABHD14B

0.97	Alpha/beta hydrolase domain-containing protein 14B

0.53	GO:0045944	positive regulation of transcription by RNA polymerase II
0.36	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.32	GO:0016311	dephosphorylation

0.50	GO:0016787	hydrolase activity
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.53	GO:0005730	nucleolus
0.50	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.50

GO:0016787

tr|Q7T388|Q7T388_DANRE
PRELI domain containing 1
Search

PRELID1

0.96	PRELI domain-containing protein 1, mitochondrial

0.55	GO:0010917	negative regulation of mitochondrial membrane potential
0.54	GO:1901857	positive regulation of cellular respiration
0.54	GO:2001140	positive regulation of phospholipid transport
0.54	GO:0070234	positive regulation of T cell apoptotic process
0.53	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.52	GO:0015914	phospholipid transport
0.51	GO:0045580	regulation of T cell differentiation
0.51	GO:0010950	positive regulation of endopeptidase activity
0.50	GO:0097035	regulation of membrane lipid distribution
0.38	GO:0006915	apoptotic process

0.57	GO:1990050	phosphatidic acid transporter activity
0.34	GO:0018024	histone-lysine N-methyltransferase activity
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.79	GO:0005758	mitochondrial intermembrane space
0.46	GO:0005654	nucleoplasm
0.42	GO:0043234	protein complex

0.34

EC:2.1.1.43

GO:0018024

tr|Q7T390|Q7T390_DANRE
Glycoprotein, synaptic 2
Search

TECR

0.90	very-long-chain enoyl-CoA reductase

0.62	GO:0006629	lipid metabolic process
0.52	GO:0055114	oxidation-reduction process
0.46	GO:0072330	monocarboxylic acid biosynthetic process
0.35	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.34	GO:1901362	organic cyclic compound biosynthetic process

0.67	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.33	GO:0005515	protein binding

0.48	GO:0005737	cytoplasm
0.46	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.44	GO:0031984	organelle subcompartment
0.40	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.67

EC:1.3

GO:0016627

sp|Q7T392|T179B_DANRE
Transmembrane protein 179B
Search

TMEM179B

0.96	Transmembrane protein 179B isoform A

0.36	GO:0016607	nuclear speck
0.35	GO:0005730	nucleolus
0.30	GO:0044425	membrane part

tr|Q7T393|Q7T393_DANRE
Zgc:64022
Search

0.75

RERG like

0.61	GO:0007165	signal transduction
0.38	GO:0003050	regulation of systemic arterial blood pressure by atrial natriuretic peptide
0.37	GO:0090277	positive regulation of peptide hormone secretion
0.37	GO:0042423	catecholamine biosynthetic process
0.35	GO:0009072	aromatic amino acid family metabolic process
0.33	GO:0055114	oxidation-reduction process

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0004511	tyrosine 3-monooxygenase activity
0.34	GO:0005506	iron ion binding
0.33	GO:0004767	sphingomyelin phosphodiesterase activity
0.32	GO:0005515	protein binding

0.32

GO:0005886

plasma membrane

0.37	EC:1.14.16.2	GO:0004511
0.33	KEGG:R02541	GO:0004767

sp|Q7T394|LIS1A_DANRE
Lissencephaly-1 homolog A
Search

PAFAH1B1

0.88	Platelet-activating factor acetylhydrolase IB subunit alpha

0.80	GO:0000132	establishment of mitotic spindle orientation
0.71	GO:0007399	nervous system development
0.68	GO:0030154	cell differentiation
0.67	GO:0051301	cell division
0.61	GO:0008090	retrograde axonal transport
0.59	GO:0090176	microtubule cytoskeleton organization involved in establishment of planar polarity
0.58	GO:0047496	vesicle transport along microtubule
0.58	GO:0051081	nuclear envelope disassembly
0.58	GO:0051661	maintenance of centrosome location
0.57	GO:0042249	establishment of planar polarity of embryonic epithelium

0.79	GO:0070840	dynein complex binding
0.55	GO:0051219	phosphoprotein binding
0.52	GO:0008017	microtubule binding
0.50	GO:0042803	protein homodimerization activity
0.41	GO:0016787	hydrolase activity
0.40	GO:0045505	dynein intermediate chain binding
0.38	GO:0034452	dynactin binding
0.38	GO:0043274	phospholipase binding
0.37	GO:0008201	heparin binding
0.36	GO:0047179	platelet-activating factor acetyltransferase activity

0.73	GO:0005874	microtubule
0.72	GO:0005815	microtubule organizing center
0.72	GO:0005875	microtubule associated complex
0.62	GO:0005819	spindle
0.61	GO:0031965	nuclear membrane
0.59	GO:1904115	axon cytoplasm
0.55	GO:0032420	stereocilium
0.55	GO:0000776	kinetochore
0.54	GO:0005938	cell cortex
0.53	GO:0031252	cell leading edge

0.41

GO:0016787

tr|Q7T396|Q7T396_DANRE
Hsd17b3 protein
Search

HSD17B3

0.70	very-long-chain 3-oxoacyl-CoA reductase

0.78	GO:0061370	testosterone biosynthetic process
0.76	GO:0030539	male genitalia development
0.51	GO:0006702	androgen biosynthetic process
0.51	GO:0055114	oxidation-reduction process
0.43	GO:0030497	fatty acid elongation
0.36	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling
0.36	GO:0032876	negative regulation of DNA endoreduplication
0.36	GO:0010884	positive regulation of lipid storage
0.35	GO:0030308	negative regulation of cell growth
0.35	GO:0031669	cellular response to nutrient levels

0.79	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity
0.44	GO:0045703	ketoreductase activity
0.43	GO:0102341	3-oxo-lignoceroyl-CoA reductase activity
0.43	GO:0102340	3-oxo-behenoyl-CoA reductase activity
0.43	GO:0102342	3-oxo-cerotoyl-CoA reductase activity
0.43	GO:0102339	3-oxo-arachidoyl-CoA reductase activity
0.36	GO:0030283	testosterone dehydrogenase [NAD(P)] activity
0.36	GO:0047035	testosterone dehydrogenase (NAD+) activity
0.34	GO:0004303	estradiol 17-beta-dehydrogenase activity
0.33	GO:0047936	glucose 1-dehydrogenase [NAD(P)] activity

0.50	GO:0005783	endoplasmic reticulum
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.40	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.79	EC:1.1.1.64	GO:0047045
0.79	KEGG:R01838	GO:0047045

tr|Q7T399|Q7T399_DANRE
Ras homolog family member Ca
Search

RHOC

0.89	Transforming protein RhoA

0.77	GO:0007264	small GTPase mediated signal transduction
0.72	GO:1902766	skeletal muscle satellite cell migration
0.70	GO:0090505	epiboly involved in wound healing
0.55	GO:0032464	positive regulation of protein homooligomerization
0.53	GO:0043297	apical junction assembly
0.53	GO:0060193	positive regulation of lipase activity
0.52	GO:0061640	cytoskeleton-dependent cytokinesis
0.49	GO:1903047	mitotic cell cycle process
0.39	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission
0.39	GO:0030241	skeletal muscle myosin thick filament assembly

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.39	GO:0032794	GTPase activating protein binding
0.37	GO:0019901	protein kinase binding
0.35	GO:0004871	signal transducer activity
0.34	GO:0004722	protein serine/threonine phosphatase activity

0.54	GO:0097610	cell surface furrow
0.53	GO:0032420	stereocilium
0.52	GO:0032155	cell division site part
0.45	GO:0005622	intracellular
0.41	GO:0071944	cell periphery
0.41	GO:0043227	membrane-bounded organelle
0.37	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space
0.32	GO:0043228	non-membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q7T3A4|RAB13_DANRE
Ras-related protein Rab-13
Search

RAB13

0.88	LOW QUALITY PROTEIN: ras-related protein Rab-13

0.56	GO:1902463	protein localization to cell leading edge
0.54	GO:0010737	protein kinase A signaling
0.54	GO:0035767	endothelial cell chemotaxis
0.53	GO:0070830	bicellular tight junction assembly
0.53	GO:0072659	protein localization to plasma membrane
0.52	GO:0032456	endocytic recycling
0.50	GO:0048731	system development
0.49	GO:0120036	plasma membrane bounded cell projection organization
0.48	GO:0048468	cell development
0.44	GO:0044795	trans-Golgi network to recycling endosome transport

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.40	GO:0071532	ankyrin repeat binding
0.40	GO:0032794	GTPase activating protein binding
0.38	GO:0034236	protein kinase A catalytic subunit binding
0.34	GO:0019003	GDP binding
0.33	GO:0005102	receptor binding

0.53	GO:0055037	recycling endosome
0.52	GO:0016328	lateral plasma membrane
0.51	GO:0030027	lamellipodium
0.51	GO:0030139	endocytic vesicle
0.51	GO:0005923	bicellular tight junction
0.50	GO:0005802	trans-Golgi network
0.50	GO:0097458	neuron part
0.45	GO:0005829	cytosol
0.43	GO:0030141	secretory granule
0.43	GO:0010008	endosome membrane

tr|Q7T3A5|Q7T3A5_DANRE
Ubiquitin-like 7
Search

UBL7

0.95	Ubiquitin like 7

0.43

GO:0005515

protein binding

tr|Q7T3A9|Q7T3A9_DANRE
Slc10a2 protein
Search

SLC10A2

0.96	Solute carrier family 10 (Sodium/bile acid cotransporter family), member 2

0.77	GO:0015721	bile acid and bile salt transport
0.69	GO:0043251	sodium-dependent organic anion transport
0.38	GO:0006814	sodium ion transport
0.35	GO:0055085	transmembrane transport

0.79	GO:0008508	bile acid:sodium symporter activity
0.69	GO:0043250	sodium-dependent organic anion transmembrane transporter activity

0.71	GO:0016324	apical plasma membrane
0.56	GO:0005902	microvillus
0.30	GO:0016021	integral component of membrane

sp|Q7T3B0|EIF3M_DANRE
Eukaryotic translation initiation factor 3 subunit M
Search

EIF3M

0.72	Eukaryotic translation initiation factor 3 subunit M

0.70	GO:0006413	translational initiation
0.69	GO:0002181	cytoplasmic translation
0.67	GO:0006446	regulation of translational initiation
0.64	GO:0022618	ribonucleoprotein complex assembly

0.71	GO:0003743	translation initiation factor activity
0.54	GO:0031369	translation initiation factor binding
0.33	GO:0016787	hydrolase activity

0.74	GO:0005852	eukaryotic translation initiation factor 3 complex
0.68	GO:0016282	eukaryotic 43S preinitiation complex
0.68	GO:0033290	eukaryotic 48S preinitiation complex
0.33	GO:0005829	cytosol

0.33

GO:0016787

tr|Q7T3B1|Q7T3B1_DANRE
Proteasome (Prosome, macropain) 26S subunit, ATPase 2
Search

PSMC2

0.80	26S proteasome regulatory subunit 7

0.78	GO:1901800	positive regulation of proteasomal protein catabolic process
0.67	GO:0030163	protein catabolic process
0.55	GO:0006508	proteolysis
0.51	GO:0043632	modification-dependent macromolecule catabolic process
0.47	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.45	GO:0034976	response to endoplasmic reticulum stress
0.45	GO:0010243	response to organonitrogen compound
0.43	GO:0044267	cellular protein metabolic process
0.36	GO:0001649	osteoblast differentiation
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition

0.79	GO:0036402	proteasome-activating ATPase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0008233	peptidase activity
0.46	GO:0017025	TBP-class protein binding
0.32	GO:0046872	metal ion binding

0.57	GO:1905369	endopeptidase complex
0.53	GO:0036464	cytoplasmic ribonucleoprotein granule
0.49	GO:0005829	cytosol
0.48	GO:0043234	protein complex
0.42	GO:0031981	nuclear lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.35	GO:0043197	dendritic spine
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.50

GO:0008233

sp|Q7T3B2|HRG1A_DANRE
Heme transporter hrg1-A
Search

SLC48A1

0.97	Heme transporter hrg1-A

0.77	GO:0015886	heme transport
0.45	GO:0048821	erythrocyte development

0.77	GO:0015232	heme transporter activity
0.45	GO:0020037	heme binding
0.33	GO:0005515	protein binding

0.55	GO:0005765	lysosomal membrane
0.53	GO:0010008	endosome membrane
0.41	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q7T3B8|Q7T3B8_DANRE
ARD1 homolog a, N-acetyltransferase
Search

NAA10

0.97	N-alpha-acetyltransferase 11, NatA catalytic subunit

0.56	GO:0006474	N-terminal protein amino acid acetylation
0.55	GO:2000719	negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric
0.53	GO:0030920	peptidyl-serine acetylation
0.50	GO:0018200	peptidyl-glutamic acid modification
0.49	GO:0018209	peptidyl-serine modification
0.48	GO:0006475	internal protein amino acid acetylation
0.35	GO:0043547	positive regulation of GTPase activity
0.34	GO:0006323	DNA packaging
0.34	GO:0000398	mRNA splicing, via spliceosome
0.33	GO:0007165	signal transduction

0.68	GO:0008080	N-acetyltransferase activity
0.46	GO:0043022	ribosome binding
0.35	GO:0005096	GTPase activator activity
0.34	GO:0005515	protein binding
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0016301	kinase activity
0.32	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0032555	purine ribonucleotide binding

0.60	GO:0031415	NatA complex
0.48	GO:0005829	cytosol
0.46	GO:0005730	nucleolus
0.42	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0071339	MLL1 complex
0.36	GO:0048188	Set1C/COMPASS complex
0.30	GO:0016020	membrane

0.68

EC:2.3.1

GO:0008080

sp|Q7T3C3|CUTA_DANRE
Protein CutA homolog
Search

CUTA

0.41	Divalent-cation tolerance protein CutA

0.77	GO:0010038	response to metal ion
0.33	GO:0016310	phosphorylation

0.37	GO:0005507	copper ion binding
0.34	GO:0004795	threonine synthase activity
0.34	GO:0004140	dephospho-CoA kinase activity

0.30

GO:0031224

intrinsic component of membrane

0.34	EC:4.2.3.1	GO:0004795
0.34	KEGG:R00130	GO:0004140

sp|Q7T3C6|CPSF5_DANRE
Cleavage and polyadenylation specificity factor subunit 5
Search

NUDT21

0.84	Nudix (Nucleoside diphosphate linked moiety X)-type motif 21

0.81	GO:0006378	mRNA polyadenylation
0.76	GO:0031439	positive regulation of mRNA cleavage
0.76	GO:1900365	positive regulation of mRNA polyadenylation
0.71	GO:0051290	protein heterotetramerization
0.70	GO:0098789	pre-mRNA cleavage required for polyadenylation

0.76	GO:0003729	mRNA binding
0.70	GO:0017091	AU-rich element binding
0.69	GO:0042826	histone deacetylase binding
0.62	GO:0003682	chromatin binding
0.62	GO:0042803	protein homodimerization activity
0.51	GO:0016787	hydrolase activity

0.81	GO:0005849	mRNA cleavage factor complex
0.73	GO:0042382	paraspeckles
0.64	GO:0005813	centrosome
0.43	GO:0005737	cytoplasm

0.51

GO:0016787

sp|Q7T3C7|RT4I1_DANRE
Reticulon-4-interacting protein 1 homolog, mitochondrial
Search

RTN4IP1

0.84	Reticulon-4-interacting protein 1, mitochondrial

0.52	GO:0055114	oxidation-reduction process
0.40	GO:0050773	regulation of dendrite development
0.38	GO:0007399	nervous system development
0.36	GO:0010842	retina layer formation
0.35	GO:0048468	cell development

0.60	GO:0008270	zinc ion binding
0.53	GO:0016491	oxidoreductase activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0005515	protein binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0005739	mitochondrion
0.53	GO:0031968	organelle outer membrane

0.53

GO:0016491

tr|Q7T3C9|Q7T3C9_DANRE
Signal recognition particle 19
Search

SRP19

0.43	Signal recognition particle

0.76	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.44	GO:0065002	intracellular protein transmembrane transport
0.43	GO:0043623	cellular protein complex assembly
0.38	GO:0042493	response to drug
0.33	GO:0006730	one-carbon metabolic process

0.78	GO:0008312	7S RNA binding
0.38	GO:0043022	ribosome binding
0.33	GO:0004089	carbonate dehydratase activity
0.33	GO:0005515	protein binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0016787	hydrolase activity

0.77	GO:0048500	signal recognition particle
0.38	GO:0005730	nucleolus
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:4.2.1.1

GO:0004089

sp|Q7T3D0|TP8L3_DANRE
Tumor necrosis factor alpha-induced protein 8-like protein 3
Search

TNFAIP8L3

0.97	Tumor necrosis factor alpha-induced protein 8-like protein 3-like

0.72	GO:0042981	regulation of apoptotic process
0.40	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
0.40	GO:0006869	lipid transport
0.40	GO:0051897	positive regulation of protein kinase B signaling
0.39	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.39	GO:0048017	inositol lipid-mediated signaling
0.38	GO:0015748	organophosphate ester transport
0.38	GO:0032007	negative regulation of TOR signaling
0.37	GO:0045087	innate immune response
0.37	GO:0015711	organic anion transport

0.40	GO:0008526	phosphatidylinositol transporter activity
0.38	GO:0035091	phosphatidylinositol binding

0.38	GO:0005654	nucleoplasm
0.37	GO:0005829	cytosol
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q7T3D1|ERO1A_DANRE
ERO1-like protein alpha
Search

ERO1A

0.93	Endoplasmic reticulum oxidoreductase alpha

0.56	GO:0022417	protein maturation by protein folding
0.55	GO:0019471	4-hydroxyproline metabolic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.51	GO:0030198	extracellular matrix organization
0.50	GO:0051209	release of sequestered calcium ion into cytosol
0.50	GO:0030968	endoplasmic reticulum unfolded protein response
0.49	GO:0051085	chaperone cofactor-dependent protein refolding
0.49	GO:0050873	brown fat cell differentiation
0.49	GO:0034975	protein folding in endoplasmic reticulum

0.83	GO:0003756	protein disulfide isomerase activity
0.76	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
0.50	GO:0015035	protein disulfide oxidoreductase activity
0.36	GO:0016301	kinase activity
0.33	GO:0005515	protein binding

0.70	GO:0005783	endoplasmic reticulum
0.44	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.43	GO:0031984	organelle subcompartment
0.38	GO:0030425	dendrite
0.33	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:5.3.4.1

GO:0003756

tr|Q7T3D3|Q7T3D3_DANRE
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
Search

GNAI1

0.92	Guanine nucleotide binding protein alpha inhibiting 1

0.82	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.57	GO:1904778	positive regulation of protein localization to cell cortex
0.54	GO:0060236	regulation of mitotic spindle organization
0.52	GO:0007212	dopamine receptor signaling pathway
0.52	GO:0016239	positive regulation of macroautophagy
0.52	GO:0051301	cell division
0.48	GO:0046039	GTP metabolic process
0.44	GO:1904321	response to forskolin
0.43	GO:0043949	regulation of cAMP-mediated signaling
0.42	GO:1901655	cellular response to ketone

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0001664	G-protein coupled receptor binding
0.41	GO:0032794	GTPase activating protein binding
0.38	GO:0000287	magnesium ion binding

0.61	GO:0030496	midbody
0.58	GO:0005813	centrosome
0.54	GO:0005730	nucleolus
0.53	GO:0099738	cell cortex region
0.50	GO:1905360	GTPase complex
0.49	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.47	GO:0000139	Golgi membrane
0.46	GO:0005789	endoplasmic reticulum membrane
0.44	GO:0098797	plasma membrane protein complex
0.39	GO:0045121	membrane raft

tr|Q7T3D5|Q7T3D5_DANRE
Programmed cell death 6
Search

PDCD6

0.94	Programmed cell death protein 6

0.52	GO:0036324	vascular endothelial growth factor receptor-2 signaling pathway
0.52	GO:1902527	positive regulation of protein monoubiquitination
0.50	GO:0014029	neural crest formation
0.50	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway
0.50	GO:0051898	negative regulation of protein kinase B signaling
0.49	GO:0001938	positive regulation of endothelial cell proliferation
0.49	GO:0010595	positive regulation of endothelial cell migration
0.49	GO:0048208	COPII vesicle coating
0.49	GO:0014032	neural crest cell development
0.49	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

0.68	GO:0005509	calcium ion binding
0.50	GO:0043495	protein membrane anchor
0.49	GO:0048306	calcium-dependent protein binding
0.47	GO:0060090	molecular adaptor activity
0.46	GO:0042803	protein homodimerization activity
0.45	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.41	GO:0000287	magnesium ion binding

0.50	GO:0070971	endoplasmic reticulum exit site
0.48	GO:0031463	Cul3-RING ubiquitin ligase complex
0.47	GO:0030127	COPII vesicle coat
0.45	GO:0000139	Golgi membrane
0.41	GO:0005634	nucleus
0.36	GO:0005768	endosome
0.36	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

tr|Q7T3E0|Q7T3E0_DANRE
Ddb1 and cul4-associated factor 7
Search

DCAF7

0.94	WD repeat-containing protein 68

0.56	GO:0048703	embryonic viscerocranium morphogenesis
0.54	GO:0051216	cartilage development
0.39	GO:0048627	myoblast development
0.39	GO:0016567	protein ubiquitination
0.38	GO:0035332	positive regulation of hippo signaling
0.38	GO:0048747	muscle fiber development
0.38	GO:0043687	post-translational protein modification
0.37	GO:0045927	positive regulation of growth
0.37	GO:0007517	muscle organ development
0.37	GO:0016573	histone acetylation

0.40	GO:0008241	peptidyl-dipeptidase activity
0.38	GO:0004180	carboxypeptidase activity
0.37	GO:0008237	metallopeptidase activity
0.37	GO:0004402	histone acetyltransferase activity
0.37	GO:0005515	protein binding
0.36	GO:0005249	voltage-gated potassium channel activity
0.35	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.35	GO:0140101	catalytic activity, acting on a tRNA
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0004672	protein kinase activity

0.71	GO:0016363	nuclear matrix
0.70	GO:0080008	Cul4-RING E3 ubiquitin ligase complex
0.66	GO:0016604	nuclear body
0.59	GO:0005829	cytosol
0.52	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.40

EC:3.4.15

GO:0008241

sp|Q7T3E4|DBR1_DANRE
Lariat debranching enzyme
Search

DBR1

0.87	Lariat debranching enzyme A

0.70	GO:0006397	mRNA processing
0.53	GO:0000375	RNA splicing, via transesterification reactions
0.51	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.34	GO:0007124	pseudohyphal growth
0.34	GO:0032197	transposition, RNA-mediated
0.34	GO:0016074	snoRNA metabolic process
0.34	GO:0051028	mRNA transport
0.33	GO:0006012	galactose metabolic process
0.33	GO:0046835	carbohydrate phosphorylation
0.33	GO:0006401	RNA catabolic process

0.62	GO:0008419	RNA lariat debranching enzyme activity
0.34	GO:0003723	RNA binding
0.34	GO:0004335	galactokinase activity
0.34	GO:0005534	galactose binding
0.33	GO:0046872	metal ion binding
0.33	GO:0016758	transferase activity, transferring hexosyl groups
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0005654	nucleoplasm
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:2.7.1.6	GO:0004335
0.34	KEGG:R01092	GO:0004335

sp|Q7T3E5|KAT3_DANRE
Kynurenine--oxoglutarate transaminase 3
Search

0.93	Kynurenine--oxoglutarate transaminase 3

0.81	GO:0097052	L-kynurenine metabolic process
0.50	GO:0006103	2-oxoglutarate metabolic process
0.49	GO:0009058	biosynthetic process
0.33	GO:0065004	protein-DNA complex assembly
0.32	GO:0006518	peptide metabolic process
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0016070	RNA metabolic process

0.85	GO:0036137	kynurenine aminotransferase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.47	GO:0042803	protein homodimerization activity
0.41	GO:0047804	cysteine-S-conjugate beta-lyase activity
0.35	GO:0047316	glutamine-phenylpyruvate transaminase activity
0.34	GO:0003723	RNA binding
0.34	GO:0017025	TBP-class protein binding
0.32	GO:0046872	metal ion binding

0.42	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.41	EC:4.4.1.13	GO:0047804
0.35	KEGG:R01375	GO:0047316

sp|Q7T3E6|BMI1B_DANRE
Polycomb complex protein BMI-1-B
Search

BMI1

0.94	Polycomb group RING finger protein 4

0.81	GO:0016574	histone ubiquitination
0.80	GO:0033092	positive regulation of immature T cell proliferation in thymus
0.80	GO:2000011	regulation of adaxial/abaxial pattern formation
0.80	GO:0048704	embryonic skeletal system morphogenesis
0.79	GO:2001234	negative regulation of apoptotic signaling pathway
0.78	GO:0009952	anterior/posterior pattern specification
0.76	GO:0030890	positive regulation of B cell proliferation
0.75	GO:0048103	somatic stem cell division
0.75	GO:0000122	negative regulation of transcription by RNA polymerase II
0.75	GO:0021532	neural tube patterning

0.79	GO:1990841	promoter-specific chromatin binding
0.72	GO:0097027	ubiquitin-protein transferase activator activity
0.70	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0071535	RING-like zinc finger domain binding
0.42	GO:0008270	zinc ion binding
0.34	GO:0003700	DNA binding transcription factor activity

0.82	GO:0031519	PcG protein complex
0.78	GO:0000792	heterochromatin
0.75	GO:0016604	nuclear body
0.73	GO:0000151	ubiquitin ligase complex
0.58	GO:0000803	sex chromosome
0.52	GO:0000790	nuclear chromatin
0.38	GO:0005829	cytosol

sp|Q7T3E8|MFR1L_DANRE
Mitochondrial fission regulator 1-like
Search

MTFR1L

0.97	Mitochondrial fission regulator 1 like

0.84	GO:0000266	mitochondrial fission
0.64	GO:0009060	aerobic respiration

0.38

GO:0005515

protein binding

0.61

GO:0005739

mitochondrion

tr|Q7T3E9|Q7T3E9_DANRE
G protein-coupled receptor 19
Search

GPR19

0.97	G protein-coupled receptor 19

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.48	GO:0007631	feeding behavior
0.46	GO:0098916	anterograde trans-synaptic signaling
0.32	GO:1901652	response to peptide
0.32	GO:0032870	cellular response to hormone stimulus

0.72	GO:0004930	G-protein coupled receptor activity
0.41	GO:0001653	peptide receptor activity
0.32	GO:0030594	neurotransmitter receptor activity
0.32	GO:0042277	peptide binding

0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q7T3F3|Q7T3F3_DANRE
Ubiquitin-conjugating enzyme E2N-like
Search

UBE2N

0.61	Ubiquitin-conjugating enzyme

0.53	GO:0000209	protein polyubiquitination
0.50	GO:0006301	postreplication repair
0.46	GO:0042769	DNA damage response, detection of DNA damage
0.45	GO:0033182	regulation of histone ubiquitination
0.44	GO:0000729	DNA double-strand break processing
0.44	GO:0045739	positive regulation of DNA repair
0.44	GO:0031058	positive regulation of histone modification
0.44	GO:0050852	T cell receptor signaling pathway
0.44	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.44	GO:0016574	histone ubiquitination

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0004842	ubiquitin-protein transferase activity
0.47	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0061659	ubiquitin-like protein ligase activity
0.45	GO:0061650	ubiquitin-like protein conjugating enzyme activity
0.43	GO:0043130	ubiquitin binding
0.34	GO:0016874	ligase activity
0.33	GO:0003723	RNA binding

0.46	GO:0031372	UBC13-MMS2 complex
0.46	GO:0035370	UBC13-UEV1A complex
0.44	GO:0005634	nucleus
0.42	GO:0000151	ubiquitin ligase complex
0.40	GO:0043233	organelle lumen
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0005737	cytoplasm
0.37	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.34	EC:6	GO:0016874
0.49	KEGG:R03876	GO:0004842

tr|Q7T3F6|Q7T3F6_DANRE
Pleckstrin homology domain containing, family F (With FYVE domain) member 1
Search

PLEKHF1

0.97	Pleckstrin homology and FYVE domain containing 1

0.53	GO:0007032	endosome organization
0.53	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.53	GO:0072659	protein localization to plasma membrane
0.51	GO:0010508	positive regulation of autophagy
0.49	GO:0000724	double-strand break repair via homologous recombination
0.47	GO:0000910	cytokinesis
0.40	GO:0035023	regulation of Rho protein signal transduction
0.38	GO:0065009	regulation of molecular function
0.37	GO:0006915	apoptotic process
0.35	GO:0046902	regulation of mitochondrial membrane permeability

0.61	GO:0032266	phosphatidylinositol-3-phosphate binding
0.55	GO:0010314	phosphatidylinositol-5-phosphate binding
0.54	GO:0046872	metal ion binding
0.53	GO:0070273	phosphatidylinositol-4-phosphate binding
0.43	GO:0000062	fatty-acyl-CoA binding
0.40	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.35	GO:0016307	phosphatidylinositol phosphate kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0032555	purine ribonucleotide binding

0.51	GO:0005764	lysosome
0.49	GO:0005768	endosome
0.37	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005634	nucleus
0.34	GO:0098852	lytic vacuole membrane
0.34	GO:0030133	transport vesicle
0.34	GO:0044433	cytoplasmic vesicle part
0.33	GO:0030496	midbody
0.33	GO:0005739	mitochondrion
0.33	GO:0005813	centrosome

0.35

GO:0016307

sp|Q7T3F7|CHRD1_DANRE
Cysteine and histidine-rich domain-containing protein 1
Search

0.74	Cysteine and histidine-rich domain-containing protein 1

0.30

GO:0065007

biological regulation

0.86	GO:0051879	Hsp90 protein binding
0.30	GO:0043169	cation binding

tr|Q7T3F9|Q7T3F9_DANRE
Mitochondrial ribosomal protein L39
Search

MRPL39

0.94	Mitochondrial ribosomal protein L39

0.35	GO:0070126	mitochondrial translational termination
0.35	GO:0070125	mitochondrial translational elongation
0.34	GO:0000002	mitochondrial genome maintenance

0.53	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.33	GO:0003723	RNA binding
0.33	GO:0003735	structural constituent of ribosome

0.53	GO:0005840	ribosome
0.48	GO:0005759	mitochondrial matrix
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q7T3G1|Q7T3G1_DANRE
GATA-binding protein 2a
Search

0.92	Endothelial transcription factor GATA-2

0.65	GO:0030097	hemopoiesis
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:1903708	positive regulation of hemopoiesis
0.55	GO:1902105	regulation of leukocyte differentiation
0.54	GO:0045597	positive regulation of cell differentiation
0.52	GO:0021514	ventral spinal cord interneuron differentiation
0.51	GO:0002696	positive regulation of leukocyte activation
0.51	GO:1903039	positive regulation of leukocyte cell-cell adhesion

0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0044212	transcription regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.45	GO:0003682	chromatin binding
0.45	GO:0008134	transcription factor binding
0.42	GO:0070742	C2H2 zinc finger domain binding
0.40	GO:0071837	HMG box domain binding
0.39	GO:0005134	interleukin-2 receptor binding

0.54	GO:0005634	nucleus
0.42	GO:0005667	transcription factor complex
0.39	GO:0070013	intracellular organelle lumen
0.37	GO:0044446	intracellular organelle part
0.36	GO:0005694	chromosome

tr|Q7T3G2|Q7T3G2_DANRE
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
Search

0.96	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma

0.54	GO:0006713	glucocorticoid catabolic process
0.53	GO:0050774	negative regulation of dendrite morphogenesis
0.52	GO:0042921	glucocorticoid receptor signaling pathway
0.51	GO:0086010	membrane depolarization during action potential
0.51	GO:2000649	regulation of sodium ion transmembrane transporter activity
0.47	GO:0006886	intracellular protein transport
0.46	GO:0045893	positive regulation of transcription, DNA-templated
0.41	GO:0048167	regulation of synaptic plasticity
0.41	GO:0007420	brain development
0.39	GO:0007507	heart development

0.77	GO:0019904	protein domain specific binding
0.53	GO:0035259	glucocorticoid receptor binding
0.51	GO:0044325	ion channel binding
0.51	GO:0017080	sodium channel regulator activity
0.48	GO:0042802	identical protein binding
0.47	GO:0019899	enzyme binding
0.46	GO:0003779	actin binding
0.46	GO:0046982	protein heterodimerization activity
0.45	GO:0004497	monooxygenase activity
0.42	GO:0005159	insulin-like growth factor receptor binding

0.40	GO:0043209	myelin sheath
0.40	GO:0005886	plasma membrane
0.38	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.36	GO:0014704	intercalated disc
0.36	GO:0012506	vesicle membrane
0.36	GO:0097708	intracellular vesicle
0.34	GO:0005925	focal adhesion
0.34	GO:0019773	proteasome core complex, alpha-subunit complex
0.34	GO:0044446	intracellular organelle part

0.34

EC:3.4.25

GO:0004298

tr|Q7T3G4|Q7T3G4_DANRE
Phosphoglycerate mutase
Search

PGAM2

0.48	Phosphoglycerate mutase

0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.55	GO:0043456	regulation of pentose-phosphate shunt
0.52	GO:0006941	striated muscle contraction
0.49	GO:0007219	Notch signaling pathway
0.47	GO:0019319	hexose biosynthetic process
0.46	GO:0006006	glucose metabolic process
0.44	GO:0007520	myoblast fusion

0.84	GO:0004082	bisphosphoglycerate mutase activity
0.78	GO:0004619	phosphoglycerate mutase activity
0.39	GO:0019901	protein kinase binding
0.35	GO:0016787	hydrolase activity
0.34	GO:0048037	cofactor binding
0.33	GO:0034061	DNA polymerase activity
0.32	GO:0003677	DNA binding

0.46	GO:0005829	cytosol
0.44	GO:0043209	myelin sheath
0.37	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.84

EC:5.4.2.4

GO:0004082

tr|Q7T3G5|Q7T3G5_DANRE
Polyadenylate-binding protein
Search

PABPC4

0.61	Polyadenylate-binding protein 1-A

0.52	GO:0061515	myeloid cell development
0.52	GO:0061013	regulation of mRNA catabolic process
0.52	GO:0043487	regulation of RNA stability
0.40	GO:0007507	heart development
0.37	GO:1902369	negative regulation of RNA catabolic process
0.37	GO:1903313	positive regulation of mRNA metabolic process
0.37	GO:0031047	gene silencing by RNA
0.36	GO:0031331	positive regulation of cellular catabolic process
0.36	GO:0000413	protein peptidyl-prolyl isomerization
0.36	GO:1903312	negative regulation of mRNA metabolic process

0.59	GO:0003723	RNA binding
0.37	GO:0031370	eukaryotic initiation factor 4G binding
0.36	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.36	GO:0043621	protein self-association
0.33	GO:0046983	protein dimerization activity

0.51	GO:0010494	cytoplasmic stress granule
0.46	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.36	GO:0005844	polysome
0.32	GO:0044446	intracellular organelle part

0.36

GO:0003755

tr|Q7T3G8|Q7T3G8_DANRE
SIX homeobox 6a
Search

SIX6

0.95	SIX homeobox 6

0.80	GO:0001654	eye development
0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.63	GO:0007420	brain development
0.61	GO:0006366	transcription by RNA polymerase II
0.59	GO:0045893	positive regulation of transcription, DNA-templated
0.57	GO:0097402	neuroblast migration
0.56	GO:1990086	lens fiber cell apoptotic process
0.56	GO:0009946	proximal/distal axis specification
0.55	GO:0061074	regulation of neural retina development
0.55	GO:0002070	epithelial cell maturation

0.73	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.55	GO:0001222	transcription corepressor binding
0.55	GO:0003677	DNA binding
0.53	GO:0042826	histone deacetylase binding
0.51	GO:0003713	transcription coactivator activity
0.49	GO:0001067	regulatory region nucleic acid binding
0.37	GO:0005102	receptor binding

0.61

GO:0005634

nucleus

tr|Q7T3H0|Q7T3H0_DANRE
Transcription factor mafT
Search

MAFF

0.88	Transcription factor MafF

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0006351	transcription, DNA-templated
0.45	GO:0045604	regulation of epidermal cell differentiation
0.45	GO:0035914	skeletal muscle cell differentiation
0.44	GO:0001701	in utero embryonic development
0.41	GO:0007567	parturition
0.41	GO:0051254	positive regulation of RNA metabolic process
0.41	GO:0010557	positive regulation of macromolecule biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.36	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.40	GO:0031974	membrane-enclosed lumen
0.38	GO:0005739	mitochondrion
0.37	GO:0044446	intracellular organelle part

sp|Q7T3H1|DCTN2_DANRE
Dynactin subunit 2
Search

DCTN2

0.95	Dynactin complex 50 kDa subunit

0.70	GO:0007017	microtubule-based process
0.53	GO:0032402	melanosome transport
0.53	GO:0071539	protein localization to centrosome
0.50	GO:0000278	mitotic cell cycle
0.50	GO:0008283	cell proliferation
0.43	GO:0007010	cytoskeleton organization
0.42	GO:0022402	cell cycle process
0.36	GO:0030719	P granule organization
0.36	GO:0060117	auditory receptor cell development
0.36	GO:0045494	photoreceptor cell maintenance

0.52	GO:0030507	spectrin binding
0.49	GO:0019901	protein kinase binding
0.47	GO:0042802	identical protein binding
0.40	GO:0003774	motor activity

0.80	GO:0005869	dynactin complex
0.52	GO:0030426	growth cone
0.52	GO:0005813	centrosome
0.49	GO:0000776	kinetochore
0.48	GO:0031982	vesicle
0.45	GO:0005829	cytosol
0.42	GO:0030286	dynein complex
0.41	GO:0005874	microtubule
0.36	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space

sp|Q7T3H2|INS1B_DANRE
Insulinoma-associated protein 1b
Search

INSM1

0.84	INSM transcriptional repressor 1

0.55	GO:0060290	transdifferentiation
0.52	GO:0003310	pancreatic A cell differentiation
0.51	GO:0003309	type B pancreatic cell differentiation
0.50	GO:0061104	adrenal chromaffin cell differentiation
0.49	GO:0071158	positive regulation of cell cycle arrest
0.49	GO:0003358	noradrenergic neuron development
0.49	GO:0000122	negative regulation of transcription by RNA polymerase II
0.48	GO:0042421	norepinephrine biosynthetic process
0.48	GO:0061549	sympathetic ganglion development
0.47	GO:0002068	glandular epithelial cell development

0.51	GO:0031490	chromatin DNA binding
0.51	GO:0001047	core promoter binding
0.48	GO:0042826	histone deacetylase binding
0.48	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0030332	cyclin binding
0.47	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.38	GO:0046872	metal ion binding
0.35	GO:0005096	GTPase activator activity
0.34	GO:0003714	transcription corepressor activity
0.33	GO:0001085	RNA polymerase II transcription factor binding

0.50	GO:0017053	transcriptional repressor complex
0.42	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part

tr|Q7T3H5|Q7T3H5_DANRE
Glycerol-3-phosphate dehydrogenase [NAD(+)]
Search

0.67	Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

0.79	GO:0046168	glycerol-3-phosphate catabolic process
0.60	GO:0005975	carbohydrate metabolic process
0.53	GO:0006734	NADH metabolic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0090038	negative regulation of protein kinase C signaling
0.52	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization
0.51	GO:2000010	positive regulation of protein localization to cell surface
0.51	GO:0086005	ventricular cardiac muscle cell action potential
0.50	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.50	GO:0010765	positive regulation of sodium ion transport

0.79	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity
0.75	GO:0042803	protein homodimerization activity
0.68	GO:0051287	NAD binding
0.50	GO:0017080	sodium channel regulator activity
0.49	GO:0044325	ion channel binding
0.36	GO:0004368	glycerol-3-phosphate dehydrogenase activity

0.76	GO:0009331	glycerol-3-phosphate dehydrogenase complex
0.39	GO:0005886	plasma membrane
0.38	GO:0005739	mitochondrion
0.36	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.34	GO:0071565	nBAF complex
0.34	GO:0071564	npBAF complex
0.34	GO:0016514	SWI/SNF complex
0.30	GO:0016021	integral component of membrane

0.79	EC:1.1.1.8 EC:1.1.1.94	GO:0004367
0.79	KEGG:R00842	GO:0004367

sp|Q7T3H7|MED18_DANRE
Mediator of RNA polymerase II transcription subunit 18
Search

MED18

0.96	Mediator of RNA polymerase II transcription subunit 18

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.37	GO:0016567	protein ubiquitination

0.79	GO:0001104	RNA polymerase II transcription cofactor activity
0.38	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0005515	protein binding

0.77	GO:0016592	mediator complex
0.48	GO:0070847	core mediator complex
0.38	GO:0000151	ubiquitin ligase complex

sp|Q7T3H9|HYI_DANRE
Putative hydroxypyruvate isomerase
Search

HYI

0.54	Hydroxypyruvate isomerase

0.75	GO:0008903	hydroxypyruvate isomerase activity
0.34	GO:0005515	protein binding

0.30

GO:0044425

membrane part

0.75	EC:5.3.1.22	GO:0008903
0.75	KEGG:R01394	GO:0008903

sp|Q7T3I0|ZC4H2_DANRE
Zinc finger C4H2 domain-containing protein
Search

ZC4H2

0.96	Hepatocellular carcinoma-associated antigen 127

0.82	GO:0045666	positive regulation of neuron differentiation
0.65	GO:0021522	spinal cord motor neuron differentiation
0.63	GO:0007528	neuromuscular junction development
0.62	GO:0048665	neuron fate specification
0.57	GO:0048666	neuron development

0.37	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding

0.72	GO:0045211	postsynaptic membrane
0.61	GO:0005634	nucleus
0.46	GO:0005737	cytoplasm
0.43	GO:0030054	cell junction
0.30	GO:0031224	intrinsic component of membrane

tr|Q7T3I6|Q7T3I6_DANRE
Vascular endothelial growth factor C
Search

VEGFC

0.97	Vascular endothelial growth factor C

0.73	GO:0010469	regulation of receptor activity
0.62	GO:0060754	positive regulation of mast cell chemotaxis
0.61	GO:0050930	induction of positive chemotaxis
0.60	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.57	GO:0050918	positive chemotaxis
0.54	GO:0008284	positive regulation of cell proliferation
0.53	GO:0045766	positive regulation of angiogenesis
0.53	GO:1901492	positive regulation of lymphangiogenesis
0.51	GO:0001936	regulation of endothelial cell proliferation
0.51	GO:0048731	system development

0.76	GO:0008083	growth factor activity
0.63	GO:0043185	vascular endothelial growth factor receptor 3 binding
0.58	GO:0042056	chemoattractant activity
0.41	GO:0042803	protein homodimerization activity
0.41	GO:0005161	platelet-derived growth factor receptor binding
0.35	GO:0043184	vascular endothelial growth factor receptor 2 binding

0.50	GO:0005615	extracellular space
0.36	GO:0031093	platelet alpha granule lumen
0.30	GO:0016020	membrane

tr|Q7T3J0|Q7T3J0_DANRE
Hairy and enhancer of split 5
Search

0.81	BHLH transcription factor

0.54	GO:0006351	transcription, DNA-templated
0.53	GO:0006355	regulation of transcription, DNA-templated
0.50	GO:0007219	Notch signaling pathway
0.50	GO:0035282	segmentation
0.49	GO:0043009	chordate embryonic development
0.49	GO:0007420	brain development
0.48	GO:0060429	epithelium development
0.47	GO:0045632	negative regulation of mechanoreceptor differentiation
0.47	GO:0072049	comma-shaped body morphogenesis
0.47	GO:0072047	proximal/distal pattern formation involved in nephron development

0.68	GO:0046983	protein dimerization activity
0.51	GO:0003677	DNA binding
0.45	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0003682	chromatin binding
0.34	GO:0008134	transcription factor binding

0.57	GO:0005634	nucleus
0.34	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome

tr|Q7T3L3|Q7T3L3_DANRE
Chaperone protein GP96
Search

HSP90B1

0.81	Heat shock protein HSP 90-alpha

0.69	GO:0006457	protein folding
0.62	GO:0006950	response to stress
0.57	GO:0031247	actin rod assembly
0.56	GO:0071318	cellular response to ATP
0.54	GO:1903513	endoplasmic reticulum to cytosol transport
0.54	GO:0032527	protein exit from endoplasmic reticulum
0.53	GO:0036293	response to decreased oxygen levels
0.51	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.50	GO:0043666	regulation of phosphoprotein phosphatase activity
0.50	GO:0043066	negative regulation of apoptotic process

0.71	GO:0051082	unfolded protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0050750	low-density lipoprotein particle receptor binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0019903	protein phosphatase binding
0.42	GO:0003723	RNA binding
0.34	GO:0019104	DNA N-glycosylase activity
0.33	GO:0005509	calcium ion binding

0.54	GO:0005788	endoplasmic reticulum lumen
0.52	GO:0030496	midbody
0.51	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0034663	endoplasmic reticulum chaperone complex
0.48	GO:0005789	endoplasmic reticulum membrane
0.46	GO:0005829	cytosol
0.43	GO:0042470	melanosome
0.39	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion

0.34

EC:3.2.2

GO:0019104

tr|Q7T3L5|Q7T3L5_DANRE
Cyclin-dependent kinase 9
Search

CDK9

0.93	Cell division protein kinase 9

0.63	GO:0006468	protein phosphorylation
0.55	GO:1903837	regulation of mRNA 3'-UTR binding
0.53	GO:0033129	positive regulation of histone phosphorylation
0.53	GO:2001168	positive regulation of histone H2B ubiquitination
0.53	GO:1902416	positive regulation of mRNA binding
0.52	GO:1900364	negative regulation of mRNA polyadenylation
0.51	GO:0071157	negative regulation of cell cycle arrest
0.50	GO:0051147	regulation of muscle cell differentiation
0.50	GO:0031297	replication fork processing
0.49	GO:0045944	positive regulation of transcription by RNA polymerase II

0.66	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0097472	cyclin-dependent protein kinase activity
0.53	GO:0097322	7SK snRNA binding
0.52	GO:0001223	transcription coactivator binding
0.49	GO:0044212	transcription regulatory region DNA binding
0.48	GO:0019901	protein kinase binding
0.47	GO:0003682	chromatin binding

0.55	GO:0008024	cyclin/CDK positive transcription elongation factor complex
0.50	GO:0016605	PML body
0.48	GO:0036464	cytoplasmic ribonucleoprotein granule
0.42	GO:0005694	chromosome
0.30	GO:0016020	membrane

0.66

GO:0004674

tr|Q7T3L7|Q7T3L7_DANRE
Cell division control protein 2
Search

CDK1

0.83	LOW QUALITY PROTEIN: cyclin-dependent kinase 1

0.63	GO:0006468	protein phosphorylation
0.53	GO:1905448	positive regulation of mitochondrial ATP synthesis coupled electron transport
0.52	GO:0051726	regulation of cell cycle
0.51	GO:0044772	mitotic cell cycle phase transition
0.50	GO:0034501	protein localization to kinetochore
0.50	GO:0018210	peptidyl-threonine modification
0.49	GO:1900182	positive regulation of protein localization to nucleus
0.49	GO:0018209	peptidyl-serine modification
0.49	GO:0016570	histone modification
0.48	GO:0030855	epithelial cell differentiation

0.67	GO:0004674	protein serine/threonine kinase activity
0.57	GO:0097472	cyclin-dependent protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0035173	histone kinase activity
0.50	GO:0030544	Hsp70 protein binding
0.49	GO:0030332	cyclin binding
0.46	GO:0003682	chromatin binding

0.53	GO:0097125	cyclin B1-CDK1 complex
0.52	GO:0072686	mitotic spindle
0.49	GO:0030496	midbody
0.49	GO:0005815	microtubule organizing center
0.49	GO:0005876	spindle microtubule
0.46	GO:0005759	mitochondrial matrix
0.45	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.35	GO:0000781	chromosome, telomeric region

0.67

GO:0004674

sp|Q7T3P8|FEM1C_DANRE
Protein fem-1 homolog C
Search

FEM1C

0.97	Fem-1 homolog c (C. elegans)

0.48	GO:0016567	protein ubiquitination
0.41	GO:0050728	negative regulation of inflammatory response
0.39	GO:0043687	post-translational protein modification
0.39	GO:0051438	regulation of ubiquitin-protein transferase activity

0.44	GO:0031867	EP4 subtype prostaglandin E2 receptor binding
0.37	GO:0004842	ubiquitin-protein transferase activity

0.67	GO:0005654	nucleoplasm
0.66	GO:0005829	cytosol

0.37

GO:0004842

tr|Q7T3Q1|Q7T3Q1_DANRE
NK lysin-like protein
Search

0.94	Antimicrobial peptide NK-lysin

0.63	GO:0006629	lipid metabolic process
0.49	GO:0043085	positive regulation of catalytic activity

0.53	GO:0001664	G-protein coupled receptor binding
0.50	GO:0008047	enzyme activator activity

0.39

GO:0005737

cytoplasm

sp|Q7T3Q2|CRIM1_DANRE
Cysteine-rich motor neuron 1 protein
Search

0.53	Cysteine-rich motor neuron 1 protein (Fragment)

0.74	GO:0010951	negative regulation of endopeptidase activity
0.61	GO:0001558	regulation of cell growth
0.34	GO:0048570	notochord morphogenesis
0.34	GO:0048009	insulin-like growth factor receptor signaling pathway
0.34	GO:0001756	somitogenesis
0.34	GO:0001568	blood vessel development
0.33	GO:0007399	nervous system development

0.77	GO:0004867	serine-type endopeptidase inhibitor activity
0.63	GO:0005520	insulin-like growth factor binding
0.36	GO:0030165	PDZ domain binding
0.35	GO:0005010	insulin-like growth factor-activated receptor activity

0.52	GO:0005576	extracellular region
0.33	GO:0031982	vesicle
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q7T3Q3|Q7T3Q3_DANRE
Cannabinoid receptor
Search

CNR1

0.90	Cannabinoid receptor

0.86	GO:0038171	cannabinoid signaling pathway
0.56	GO:0007413	axonal fasciculation
0.53	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.53	GO:0099553	trans-synaptic signaling by endocannabinoid, modulating synaptic transmission
0.48	GO:0042593	glucose homeostasis
0.47	GO:0060259	regulation of feeding behavior
0.46	GO:0048520	positive regulation of behavior
0.45	GO:0001889	liver development
0.44	GO:0048667	cell morphogenesis involved in neuron differentiation
0.44	GO:0048812	neuron projection morphogenesis

0.86	GO:0004949	cannabinoid receptor activity
0.36	GO:1904483	synthetic cannabinoid binding
0.33	GO:0008144	drug binding
0.33	GO:0005515	protein binding

0.50	GO:0042734	presynaptic membrane
0.49	GO:0030426	growth cone
0.49	GO:0030424	axon
0.39	GO:0005741	mitochondrial outer membrane
0.36	GO:0098857	membrane microdomain
0.35	GO:0030175	filopodium
0.34	GO:0044297	cell body
0.30	GO:0031224	intrinsic component of membrane

tr|Q7T3Q4|Q7T3Q4_DANRE
Opiate receptor-like
Search

0.85	Opiate receptor-like

0.85	GO:0038003	opioid receptor signaling pathway
0.53	GO:0019233	sensory perception of pain
0.51	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.51	GO:0007218	neuropeptide signaling pathway
0.50	GO:0098916	anterograde trans-synaptic signaling

0.86	GO:0004985	opioid receptor activity
0.72	GO:0042923	neuropeptide binding

0.54	GO:0045203	integral component of cell outer membrane
0.50	GO:0043005	neuron projection
0.45	GO:0005887	integral component of plasma membrane

sp|Q7T3S3|CHSTB_DANRE
Carbohydrate sulfotransferase 11
Search

CHST11

0.66	Carbohydrate sulfotransferase

0.67	GO:0016051	carbohydrate biosynthetic process
0.57	GO:0030206	chondroitin sulfate biosynthetic process
0.56	GO:0036342	post-anal tail morphogenesis
0.56	GO:0002063	chondrocyte development
0.55	GO:0007585	respiratory gaseous exchange
0.55	GO:0048703	embryonic viscerocranium morphogenesis
0.55	GO:0042733	embryonic digit morphogenesis
0.54	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.52	GO:0048589	developmental growth
0.51	GO:0009791	post-embryonic development

0.78

GO:0008146

sulfotransferase activity

0.74	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

0.78

GO:0008146

sp|Q7T3S5|B3G5A_DANRE
Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase A
Search

B3GNT5

0.57	Hexosyltransferase

0.73	GO:0006486	protein glycosylation
0.51	GO:0007417	central nervous system development
0.33	GO:0030311	poly-N-acetyllactosamine biosynthetic process

0.79	GO:0008378	galactosyltransferase activity
0.59	GO:0008457	beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity
0.33	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity

0.73	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.79

GO:0008378

sp|Q7T3T8|ZAR1_DANRE
Zygote arrest protein 1
Search

ZAR1

0.90	Zygote arrest protein 1

0.54	GO:0007275	multicellular organism development
0.52	GO:1905881	positive regulation of oogenesis
0.49	GO:0016441	posttranscriptional gene silencing
0.47	GO:0017148	negative regulation of translation
0.39	GO:0000003	reproduction

0.52	GO:1903231	mRNA binding involved in posttranscriptional gene silencing
0.43	GO:0005515	protein binding

0.48	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q7T3X9|NARPB_DANRE
Notch-regulated ankyrin repeat-containing protein B
Search

NRARP

0.52	Notch-regulated ankyrin repeat-containing protein B

0.82	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.79	GO:0001569	branching involved in blood vessel morphogenesis
0.72	GO:1902367	negative regulation of Notch signaling pathway involved in somitogenesis
0.70	GO:0060828	regulation of canonical Wnt signaling pathway
0.70	GO:0001938	positive regulation of endothelial cell proliferation
0.69	GO:0022407	regulation of cell-cell adhesion
0.69	GO:0007219	Notch signaling pathway
0.69	GO:0032525	somite rostral/caudal axis specification
0.67	GO:0030177	positive regulation of Wnt signaling pathway
0.67	GO:0045620	negative regulation of lymphocyte differentiation

0.49	GO:0019901	protein kinase binding
0.35	GO:0003677	DNA binding

0.40	GO:0005913	cell-cell adherens junction
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q7T3Y0|NARPA_DANRE
Notch-regulated ankyrin repeat-containing protein A
Search

NRARP

0.52	Notch-regulated ankyrin repeat-containing protein A

0.82	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.78	GO:0001569	branching involved in blood vessel morphogenesis
0.71	GO:1902367	negative regulation of Notch signaling pathway involved in somitogenesis
0.70	GO:0060828	regulation of canonical Wnt signaling pathway
0.69	GO:0001938	positive regulation of endothelial cell proliferation
0.68	GO:0022407	regulation of cell-cell adhesion
0.68	GO:0007219	Notch signaling pathway
0.68	GO:0032525	somite rostral/caudal axis specification
0.66	GO:0030177	positive regulation of Wnt signaling pathway
0.66	GO:0045620	negative regulation of lymphocyte differentiation

0.49	GO:0019901	protein kinase binding
0.35	GO:0003677	DNA binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005913	cell-cell adherens junction
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q7ZSX3|PTF1A_DANRE
Pancreas transcription factor 1 subunit alpha
Search

PTF1A

0.94	Pancreas transcription factor 1 subunit alpha

0.64	GO:0035881	amacrine cell differentiation
0.61	GO:0031016	pancreas development
0.56	GO:0048384	retinoic acid receptor signaling pathway
0.56	GO:0009887	animal organ morphogenesis
0.55	GO:0061074	regulation of neural retina development
0.55	GO:0030902	hindbrain development
0.54	GO:0045893	positive regulation of transcription, DNA-templated
0.53	GO:0035272	exocrine system development
0.53	GO:0048663	neuron fate commitment
0.52	GO:0055123	digestive system development

0.68	GO:0046983	protein dimerization activity
0.54	GO:0070888	E-box binding
0.52	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0003682	chromatin binding
0.40	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.35	GO:0004634	phosphopyruvate hydratase activity
0.34	GO:0000287	magnesium ion binding
0.33	GO:0005230	extracellular ligand-gated ion channel activity
0.33	GO:0099600	transmembrane receptor activity
0.32	GO:0038023	signaling receptor activity

0.51	GO:0005667	transcription factor complex
0.38	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.33	GO:0043233	organelle lumen
0.33	GO:1902494	catalytic complex
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.35

EC:4.2.1.11

GO:0004634

tr|Q7ZSY3|Q7ZSY3_DANRE
Brahma protein-like protein 1
Search

SMARCA4

0.79	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

0.81	GO:0043044	ATP-dependent chromatin remodeling
0.64	GO:0003407	neural retina development
0.64	GO:1902661	positive regulation of glucose mediated signaling pathway
0.62	GO:1901838	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I
0.62	GO:0060766	negative regulation of androgen receptor signaling pathway
0.62	GO:0043923	positive regulation by host of viral transcription
0.61	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II
0.60	GO:0031498	chromatin disassembly
0.60	GO:0032986	protein-DNA complex disassembly
0.58	GO:0030177	positive regulation of Wnt signaling pathway

0.79	GO:0042393	histone binding
0.63	GO:0030957	Tat protein binding
0.61	GO:0070182	DNA polymerase binding
0.61	GO:0050681	androgen receptor binding
0.61	GO:0016887	ATPase activity
0.60	GO:0001164	RNA polymerase I CORE element sequence-specific DNA binding
0.60	GO:0001105	RNA polymerase II transcription coactivator activity
0.59	GO:0047485	protein N-terminus binding
0.59	GO:0002039	p53 binding
0.59	GO:0140033	acetylation-dependent protein binding

0.82	GO:0016514	SWI/SNF complex
0.59	GO:0071564	npBAF complex
0.53	GO:0005730	nucleolus

0.61

GO:0016887

tr|Q7ZSZ0|Q7ZSZ0_DANRE
RAB1A, member RAS oncogene family
Search

RAB1A

0.88	Ras-associated binding-GTPase 1a4

0.52	GO:0072606	interleukin-8 secretion
0.52	GO:0030252	growth hormone secretion
0.52	GO:0032402	melanosome transport
0.51	GO:0034446	substrate adhesion-dependent cell spreading
0.51	GO:0090110	cargo loading into COPII-coated vesicle
0.51	GO:1903020	positive regulation of glycoprotein metabolic process
0.50	GO:0047496	vesicle transport along microtubule
0.49	GO:0000045	autophagosome assembly
0.48	GO:0016477	cell migration
0.48	GO:0007030	Golgi organization

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0045296	cadherin binding
0.34	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity

0.51	GO:0042470	melanosome
0.48	GO:0000139	Golgi membrane
0.43	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0005769	early endosome
0.36	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.35	GO:0030133	transport vesicle
0.34	GO:0043025	neuronal cell body
0.34	GO:0099503	secretory vesicle
0.34	GO:0098793	presynapse

0.34

EC:2.4.2.31

GO:0003956

tr|Q7ZSZ9|Q7ZSZ9_DANRE
Rac1
Search

RAC1

0.80	Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

0.75	GO:0007264	small GTPase mediated signal transduction
0.52	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.52	GO:0032707	negative regulation of interleukin-23 production
0.51	GO:0048012	hepatocyte growth factor receptor signaling pathway
0.51	GO:0010592	positive regulation of lamellipodium assembly
0.51	GO:0060263	regulation of respiratory burst
0.50	GO:0051894	positive regulation of focal adhesion assembly
0.50	GO:0090023	positive regulation of neutrophil chemotaxis
0.50	GO:0097178	ruffle assembly
0.50	GO:0030032	lamellipodium assembly

0.67	GO:0003924	GTPase activity
0.65	GO:0005525	GTP binding
0.51	GO:0031996	thioesterase binding
0.47	GO:0019901	protein kinase binding
0.44	GO:0051022	Rho GDP-dissociation inhibitor binding
0.40	GO:0048306	calcium-dependent protein binding
0.40	GO:0030742	GTP-dependent protein binding
0.39	GO:0051117	ATPase binding
0.39	GO:0042826	histone deacetylase binding
0.38	GO:0017137	Rab GTPase binding

0.50	GO:0005884	actin filament
0.49	GO:0043197	dendritic spine
0.49	GO:0055038	recycling endosome membrane
0.49	GO:0032587	ruffle membrane
0.48	GO:0030027	lamellipodium
0.47	GO:0005802	trans-Golgi network
0.47	GO:0036464	cytoplasmic ribonucleoprotein granule
0.40	GO:0042470	melanosome
0.40	GO:0097732	9+2 non-motile cilium
0.40	GO:0030426	growth cone

0.34

GO:0004402

tr|Q7ZT06|Q7ZT06_DANRE
Ectodermal-neural cortex 3
Search

0.76	Ectoderm-neural cortex protein 1

0.70	GO:0048731	system development
0.60	GO:0010499	proteasomal ubiquitin-independent protein catabolic process
0.56	GO:0016567	protein ubiquitination
0.56	GO:0006417	regulation of translation
0.56	GO:0034249	negative regulation of cellular amide metabolic process
0.53	GO:0032269	negative regulation of cellular protein metabolic process
0.53	GO:0007368	determination of left/right symmetry
0.52	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.51	GO:0010629	negative regulation of gene expression
0.39	GO:0031346	positive regulation of cell projection organization

0.68

GO:0003779

actin binding

0.63	GO:0031463	Cul3-RING ubiquitin ligase complex
0.41	GO:0005737	cytoplasm
0.40	GO:0016363	nuclear matrix
0.39	GO:0043025	neuronal cell body
0.38	GO:0000790	nuclear chromatin
0.38	GO:0005730	nucleolus
0.37	GO:0005654	nucleoplasm
0.35	GO:0005856	cytoskeleton

tr|Q7ZT18|Q7ZT18_DANRE
Pro-opiomelanocortin protein
Search

0.51	Proopiomelanocorticotrophin A

0.76	GO:0010469	regulation of receptor activity
0.46	GO:0007218	neuropeptide signaling pathway
0.44	GO:0033059	cellular pigmentation
0.44	GO:0033555	multicellular organismal response to stress
0.43	GO:0051648	vesicle localization
0.41	GO:2000852	regulation of corticosterone secretion
0.36	GO:0071376	cellular response to corticotropin-releasing hormone stimulus
0.36	GO:0071222	cellular response to lipopolysaccharide
0.34	GO:0032098	regulation of appetite
0.34	GO:0032720	negative regulation of tumor necrosis factor production

0.79	GO:0005179	hormone activity
0.38	GO:0001664	G-protein coupled receptor binding

0.66	GO:0005576	extracellular region
0.38	GO:0030141	secretory granule
0.30	GO:0016020	membrane

tr|Q7ZT36|Q7ZT36_DANRE
Parvalbumin 3
Search

0.90	Novel protein containing two EF hand domains

0.70

GO:0005509

calcium ion binding

0.42	GO:0043679	axon terminus
0.41	GO:0030425	dendrite
0.41	GO:0030424	axon
0.37	GO:0016528	sarcoplasm

sp|Q7ZT42|SND1_DANRE
Staphylococcal nuclease domain-containing protein 1
Search

SND1

0.85	Staphylococcal nuclease and tudor domain containing 1

0.79	GO:0031047	gene silencing by RNA
0.46	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.38	GO:0006401	RNA catabolic process

0.46	GO:0004518	nuclease activity
0.42	GO:0045296	cadherin binding
0.40	GO:0003676	nucleic acid binding

0.85	GO:0016442	RISC complex
0.43	GO:0097433	dense body
0.39	GO:0005634	nucleus
0.39	GO:0005829	cytosol
0.37	GO:0005739	mitochondrion

0.46

EC:3.1

GO:0004518

sp|Q7ZT82|RFX1L_DANRE
RNA binding protein fox-1 homolog 1-like
Search

0.87	RNA binding protein fox-1

0.80	GO:0043484	regulation of RNA splicing
0.69	GO:0008380	RNA splicing
0.66	GO:0006397	mRNA processing
0.48	GO:0048739	cardiac muscle fiber development
0.46	GO:0048741	skeletal muscle fiber development
0.45	GO:0050684	regulation of mRNA processing
0.41	GO:0007399	nervous system development

0.59	GO:0003723	RNA binding
0.37	GO:0003677	DNA binding
0.32	GO:0005515	protein binding

0.59	GO:0005634	nucleus
0.45	GO:0043204	perikaryon
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q7ZTA3|Q7ZTA3_DANRE
Melanocyte-stimulating hormone receptor
Search

MC1R

0.70	Melanocyte-stimulating hormone receptor

0.68

GO:0007186

G-protein coupled receptor signaling pathway

0.81	GO:0004980	melanocyte-stimulating hormone receptor activity
0.33	GO:0005515	protein binding

0.54	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q7ZTI0|Q7ZTI0_DANRE
Sjogren syndrome antigen B (Autoantigen La)
Search

SSB

0.97	Sjogren syndrome antigen B

0.70	GO:0071045	nuclear histone mRNA catabolic process
0.68	GO:1903608	protein localization to cytoplasmic stress granule
0.67	GO:0075522	IRES-dependent viral translational initiation
0.66	GO:0071431	tRNA-containing ribonucleoprotein complex export from nucleus
0.65	GO:0051031	tRNA transport
0.64	GO:0097064	ncRNA export from nucleus
0.63	GO:0006396	RNA processing
0.50	GO:0006399	tRNA metabolic process

0.67	GO:1990825	sequence-specific mRNA binding
0.65	GO:0008266	poly(U) RNA binding
0.54	GO:0000049	tRNA binding

0.61	GO:0005634	nucleus
0.61	GO:0030529	intracellular ribonucleoprotein complex
0.41	GO:0005737	cytoplasm

sp|Q7ZTI3|RARAB_DANRE
Retinoic acid receptor alpha-B
Search

RARA

0.92	Retinoic acid receptor RAR-alpha

0.85	GO:0048384	retinoic acid receptor signaling pathway
0.77	GO:0043401	steroid hormone mediated signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.54	GO:0060010	Sertoli cell fate commitment
0.52	GO:0045630	positive regulation of T-helper 2 cell differentiation
0.52	GO:0032526	response to retinoic acid
0.52	GO:0060591	chondroblast differentiation

0.85	GO:0003708	retinoic acid receptor activity
0.78	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0008270	zinc ion binding
0.52	GO:0043422	protein kinase B binding
0.51	GO:0001972	retinoic acid binding
0.51	GO:0051393	alpha-actinin binding
0.50	GO:0051018	protein kinase A binding
0.49	GO:0031490	chromatin DNA binding
0.48	GO:0003714	transcription corepressor activity

0.60	GO:0005634	nucleus
0.48	GO:0043025	neuronal cell body
0.48	GO:0030425	dendrite
0.46	GO:0015629	actin cytoskeleton
0.45	GO:0000785	chromatin
0.44	GO:0005829	cytosol
0.44	GO:0070013	intracellular organelle lumen
0.38	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0009986	cell surface
0.30	GO:0016020	membrane

sp|Q7ZTI5|MED21_DANRE
Mediator of RNA polymerase II transcription subunit 21
Search

MED21

0.92	Mediator of RNA polymerase II transcription subunit 21

0.55	GO:0006351	transcription, DNA-templated
0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.52	GO:0019827	stem cell population maintenance
0.50	GO:0001824	blastocyst development
0.46	GO:1902680	positive regulation of RNA biosynthetic process
0.37	GO:0016567	protein ubiquitination

0.50	GO:0003712	transcription cofactor activity
0.45	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.38	GO:0061630	ubiquitin protein ligase activity
0.35	GO:0005515	protein binding
0.34	GO:0003899	DNA-directed 5'-3' RNA polymerase activity

0.73	GO:0016592	mediator complex
0.38	GO:0000151	ubiquitin ligase complex

0.34

GO:0003899

sp|Q7ZTS4|K1C18_DANRE
Keratin, type I cytoskeletal 18
Search

KRT18

0.90	'Keratin, type I cytoskeletal 18'

0.46	GO:0043000	Golgi to plasma membrane CFTR protein transport
0.43	GO:0045104	intermediate filament cytoskeleton organization
0.43	GO:0097284	hepatocyte apoptotic process
0.42	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.42	GO:0097191	extrinsic apoptotic signaling pathway
0.41	GO:0043066	negative regulation of apoptotic process
0.41	GO:0098609	cell-cell adhesion
0.35	GO:0070268	cornification
0.34	GO:0009653	anatomical structure morphogenesis
0.34	GO:0097010	eukaryotic translation initiation factor 4F complex assembly

0.62	GO:0005198	structural molecule activity
0.44	GO:0098641	cadherin binding involved in cell-cell adhesion
0.43	GO:0097110	scaffold protein binding
0.34	GO:0003723	RNA binding

0.79	GO:0005882	intermediate filament
0.43	GO:0034451	centriolar satellite
0.42	GO:0005913	cell-cell adherens junction
0.40	GO:0005829	cytosol
0.36	GO:0016363	nuclear matrix
0.35	GO:0005730	nucleolus
0.35	GO:0071944	cell periphery
0.35	GO:0070062	extracellular exosome
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0036338	viral membrane

tr|Q7ZTT4|Q7ZTT4_DANRE
Chloride intracellular channel 4
Search

CLIC4

0.83	Chloride intracellular channel protein 4

0.76	GO:0034765	regulation of ion transmembrane transport
0.76	GO:1902476	chloride transmembrane transport
0.54	GO:0061299	retina vasculature morphogenesis in camera-type eye
0.54	GO:0001886	endothelial cell morphogenesis
0.52	GO:0007035	vacuolar acidification
0.52	GO:0030216	keratinocyte differentiation
0.52	GO:0071277	cellular response to calcium ion
0.52	GO:0035264	multicellular organism growth
0.52	GO:0001525	angiogenesis
0.51	GO:0048754	branching morphogenesis of an epithelial tube

0.76	GO:0005254	chloride channel activity
0.73	GO:0022832	voltage-gated channel activity
0.71	GO:0022839	ion gated channel activity
0.71	GO:0008381	mechanosensitive ion channel activity
0.46	GO:0004364	glutathione transferase activity
0.35	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding

0.80	GO:0034707	chloride channel complex
0.51	GO:0005902	microvillus
0.51	GO:0016363	nuclear matrix
0.51	GO:0030496	midbody
0.50	GO:0045177	apical part of cell
0.49	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0005813	centrosome
0.48	GO:0005911	cell-cell junction
0.48	GO:0009986	cell surface
0.45	GO:0005829	cytosol

0.46

EC:2.5.1.18

GO:0004364

tr|Q7ZTT6|Q7ZTT6_DANRE
Solute carrier family 25 (Mitochondrial carrier: glutamate), member 22
Search

SLC25A22

0.90	mitochondrial Glutamate carrier 1

0.54	GO:0055085	transmembrane transport
0.52	GO:0015813	L-glutamate transport
0.44	GO:0006839	mitochondrial transport
0.33	GO:0015992	proton transport
0.33	GO:0007165	signal transduction

0.53	GO:0005313	L-glutamate transmembrane transporter activity
0.43	GO:0015370	solute:sodium symporter activity
0.35	GO:0005280	amino acid:proton symporter activity

0.44	GO:0031966	mitochondrial membrane
0.44	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

tr|Q7ZTU4|Q7ZTU4_DANRE
Platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit
Search

PAFAH1B3

0.92	platelet-activating factor acetylhydrolase IB subunit gamma

0.56	GO:0007283	spermatogenesis
0.50	GO:0007420	brain development
0.50	GO:0016239	positive regulation of macroautophagy
0.40	GO:0016042	lipid catabolic process
0.35	GO:0043312	neutrophil degranulation

0.57	GO:0047179	platelet-activating factor acetyltransferase activity
0.49	GO:0042802	identical protein binding
0.47	GO:0016787	hydrolase activity
0.40	GO:0046982	protein heterodimerization activity

0.49	GO:0001650	fibrillar center
0.46	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane
0.38	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.30	GO:0031224	intrinsic component of membrane

0.57

EC:2.3.1.149

GO:0047179

sp|Q7ZTU9|TBX2_DANRE
T-box transcription factor TBX2b
Search

TBX2

0.92

T-box 2

0.77	GO:1901211	negative regulation of cardiac chamber formation
0.77	GO:1901208	negative regulation of heart looping
0.75	GO:0007521	muscle cell fate determination
0.74	GO:0003256	regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
0.73	GO:0060465	pharynx development
0.73	GO:0036302	atrioventricular canal development
0.73	GO:0060596	mammary placode formation
0.72	GO:0090398	cellular senescence
0.72	GO:0060045	positive regulation of cardiac muscle cell proliferation
0.72	GO:0003148	outflow tract septum morphogenesis

0.69	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.67	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.62	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus

sp|Q7ZTW4|SGK1_DANRE
Serine/threonine-protein kinase Sgk1
Search

SGK1

0.94	Dual specificity mitogen-activated protein kinase kinase 5

0.63	GO:0006468	protein phosphorylation
0.46	GO:0018209	peptidyl-serine modification
0.45	GO:0048812	neuron projection morphogenesis
0.45	GO:0006950	response to stress
0.42	GO:0006915	apoptotic process
0.42	GO:0051716	cellular response to stimulus
0.39	GO:0023052	signaling
0.39	GO:0007154	cell communication
0.37	GO:0050794	regulation of cellular process
0.36	GO:0051050	positive regulation of transport

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.51	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.46	GO:0035091	phosphatidylinositol binding
0.35	GO:0043423	3-phosphoinositide-dependent protein kinase binding
0.35	GO:0048156	tau protein binding
0.35	GO:0017081	chloride channel regulator activity

0.51	GO:0016607	nuclear speck
0.46	GO:0005829	cytosol
0.41	GO:0005783	endoplasmic reticulum
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.36	GO:0005739	mitochondrion
0.35	GO:0005886	plasma membrane
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0043005	neuron projection
0.30	GO:0016021	integral component of membrane

0.70

GO:0004674

tr|Q7ZTX2|Q7ZTX2_DANRE
WD repeat domain 5
Search

WDR5

0.92	WD repeat-containing protein 5

0.77	GO:0043982	histone H4-K8 acetylation
0.77	GO:0043981	histone H4-K5 acetylation
0.76	GO:0051568	histone H3-K4 methylation
0.76	GO:0043984	histone H4-K16 acetylation
0.73	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
0.72	GO:0043966	histone H3 acetylation
0.65	GO:0001501	skeletal system development
0.61	GO:0060271	cilium assembly
0.54	GO:0007482	haltere development
0.51	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process

0.78	GO:0043996	histone acetyltransferase activity (H4-K8 specific)
0.78	GO:0046972	histone acetyltransferase activity (H4-K16 specific)
0.78	GO:0043995	histone acetyltransferase activity (H4-K5 specific)
0.71	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.71	GO:0140034	methylation-dependent protein binding
0.68	GO:0042393	histone binding
0.36	GO:0003743	translation initiation factor activity

0.77	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.77	GO:0044666	MLL3/4 complex
0.74	GO:0048188	Set1C/COMPASS complex
0.72	GO:0044665	MLL1/2 complex
0.63	GO:0036064	ciliary basal body
0.54	GO:0044545	NSL complex
0.30	GO:0016020	membrane

sp|Q7ZTY4|RBBP7_DANRE
Histone-binding protein RBBP7
Search

RBBP4

0.80	RB binding protein 4, chromatin remodeling factor

0.48	GO:0006335	DNA replication-dependent nucleosome assembly
0.47	GO:0006336	DNA replication-independent nucleosome assembly
0.46	GO:0006338	chromatin remodeling
0.40	GO:0016569	covalent chromatin modification
0.39	GO:0006260	DNA replication
0.38	GO:0007049	cell cycle
0.38	GO:0060416	response to growth hormone
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:0031101	fin regeneration
0.36	GO:1903506	regulation of nucleic acid-templated transcription

0.47	GO:0042826	histone deacetylase binding
0.43	GO:0008094	DNA-dependent ATPase activity
0.36	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.36	GO:0031492	nucleosomal DNA binding
0.36	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0004407	histone deacetylase activity
0.34	GO:0042393	histone binding

0.61	GO:0005634	nucleus
0.51	GO:0033186	CAF-1 complex
0.47	GO:0034708	methyltransferase complex
0.46	GO:0017053	transcriptional repressor complex
0.44	GO:0031974	membrane-enclosed lumen
0.43	GO:0000785	chromatin
0.42	GO:0005829	cytosol
0.41	GO:1904949	ATPase complex

0.34

EC:3.5.1.98

GO:0004407

tr|Q7ZTY5|Q7ZTY5_DANRE
Eukaryotic translation initiation factor 2B, subunit 3 gamma
Search

EIF2B3

0.89	Eukaryotic translation initiation factor 2B subunit gamma

0.67	GO:0006413	translational initiation
0.58	GO:1904628	cellular response to phorbol 13-acetate 12-myristate
0.56	GO:0014003	oligodendrocyte development
0.46	GO:0065009	regulation of molecular function
0.38	GO:0021766	hippocampus development
0.38	GO:0009749	response to glucose
0.37	GO:0043434	response to peptide hormone
0.37	GO:0009408	response to heat

0.68	GO:0003743	translation initiation factor activity
0.59	GO:0016779	nucleotidyltransferase activity
0.51	GO:0005085	guanyl-nucleotide exchange factor activity
0.32	GO:0003735	structural constituent of ribosome

0.56	GO:0005851	eukaryotic translation initiation factor 2B complex
0.33	GO:0005829	cytosol
0.32	GO:0005840	ribosome

0.59

GO:0016779

sp|Q7ZTY6|CG026_DANRE
Uncharacterized protein C7orf26 homolog
Search

0.10	Transferrin receptor 1a

0.38

GO:0055114

oxidation-reduction process

0.47	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.44	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.42	GO:0020037	heme binding
0.42	GO:0005506	iron ion binding
0.39	GO:0140096	catalytic activity, acting on a protein

0.30

GO:0031224

intrinsic component of membrane

0.47

EC:2.3.1

GO:0016747

sp|Q7ZTY7|USE1_DANRE
Vesicle transport protein USE1
Search

USE1

0.95	Unconventional SNARE in the ER 1

0.39	GO:0043547	positive regulation of GTPase activity
0.39	GO:0007018	microtubule-based movement
0.39	GO:0071786	endoplasmic reticulum tubular network organization
0.39	GO:0060628	regulation of ER to Golgi vesicle-mediated transport
0.37	GO:0016192	vesicle-mediated transport
0.37	GO:0035556	intracellular signal transduction
0.37	GO:0007041	lysosomal transport
0.36	GO:0015031	protein transport
0.35	GO:0030163	protein catabolic process
0.35	GO:0032940	secretion by cell

0.40	GO:0005096	GTPase activator activity
0.39	GO:0003777	microtubule motor activity
0.39	GO:0008017	microtubule binding
0.39	GO:0003779	actin binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0046872	metal ion binding
0.32	GO:0003677	DNA binding

0.49	GO:0005783	endoplasmic reticulum
0.40	GO:0016459	myosin complex
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.36	GO:0005764	lysosome
0.30	GO:0031224	intrinsic component of membrane

tr|Q7ZTY9|Q7ZTY9_DANRE
Small nuclear ribonucleoprotein 40 (U5)
Search

SNRNP40

0.92	Small nuclear ribonucleoprotein U5 subunit 40

0.47	GO:0008380	RNA splicing
0.37	GO:0006397	mRNA processing
0.34	GO:0006464	cellular protein modification process
0.32	GO:0016310	phosphorylation

0.41	GO:0003723	RNA binding
0.35	GO:0016905	myosin heavy chain kinase activity
0.33	GO:0005515	protein binding

0.62	GO:0019013	viral nucleocapsid
0.59	GO:0030529	intracellular ribonucleoprotein complex
0.54	GO:0016607	nuclear speck
0.49	GO:0005829	cytosol
0.48	GO:0120114	Sm-like protein family complex
0.47	GO:1902494	catalytic complex
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:2.7.11.7

GO:0016905

sp|Q7ZTZ2|RLP24_DANRE
Probable ribosome biogenesis protein RLP24
Search

RSL24D1

0.95	Ribosomal L24 domain-containing protein 1

0.58	GO:1902626	assembly of large subunit precursor of preribosome
0.55	GO:0043043	peptide biosynthetic process
0.53	GO:0000027	ribosomal large subunit assembly
0.51	GO:0044267	cellular protein metabolic process
0.50	GO:0010467	gene expression
0.49	GO:0009059	macromolecule biosynthetic process
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.33	GO:0055114	oxidation-reduction process

0.58	GO:0003735	structural constituent of ribosome
0.44	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.34	GO:0050660	flavin adenine dinucleotide binding
0.34	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.34	GO:0004519	endonuclease activity

0.60	GO:0005730	nucleolus
0.59	GO:0005840	ribosome
0.51	GO:0044445	cytosolic part
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:1.1

GO:0016614

tr|Q7ZTZ3|Q7ZTZ3_DANRE
Phosphomannomutase
Search

PMM2

0.56	Phosphomannomutase

0.81	GO:0009298	GDP-mannose biosynthetic process
0.48	GO:0006013	mannose metabolic process
0.48	GO:0006487	protein N-linked glycosylation
0.45	GO:0045047	protein targeting to ER
0.42	GO:0090171	chondrocyte morphogenesis
0.40	GO:1990830	cellular response to leukemia inhibitory factor
0.40	GO:0048701	embryonic cranial skeleton morphogenesis
0.38	GO:0022008	neurogenesis

0.83	GO:0004615	phosphomannomutase activity
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.52	GO:0043025	neuronal cell body
0.49	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome

0.83	EC:5.4.2.8	GO:0004615
0.83	KEGG:R01818	GO:0004615

tr|Q7ZTZ4|Q7ZTZ4_DANRE
Fibrillarin
Search

FBL

0.75	rRNA 2'-O-methyltransferase fibrillarin

0.69	GO:0006364	rRNA processing
0.66	GO:0008033	tRNA processing
0.63	GO:0032259	methylation
0.53	GO:0016074	snoRNA metabolic process
0.50	GO:0048254	snoRNA localization
0.49	GO:0016570	histone modification
0.48	GO:0008213	protein alkylation
0.47	GO:0043628	ncRNA 3'-end processing
0.43	GO:0009451	RNA modification
0.37	GO:0001649	osteoblast differentiation

0.63	GO:0008168	methyltransferase activity
0.59	GO:0003723	RNA binding
0.49	GO:0001094	TFIID-class transcription factor binding
0.48	GO:0051117	ATPase binding
0.45	GO:0140102	catalytic activity, acting on a rRNA
0.42	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0016301	kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding

0.54	GO:0015030	Cajal body
0.51	GO:0044452	nucleolar part
0.48	GO:0005732	small nucleolar ribonucleoprotein complex
0.48	GO:0032040	small-subunit processome
0.36	GO:0070062	extracellular exosome
0.35	GO:0005694	chromosome
0.30	GO:0016020	membrane

0.63

GO:0008168

sp|Q7ZU13|SPNS1_DANRE
Protein spinster homolog 1
Search

SPNS1

0.93	Vesicular glutamate transporter 2

0.55	GO:0055085	transmembrane transport
0.49	GO:0003376	sphingosine-1-phosphate signaling pathway
0.45	GO:0006869	lipid transport
0.42	GO:0040011	locomotion
0.36	GO:0090398	cellular senescence
0.36	GO:0097352	autophagosome maturation

0.50	GO:0046624	sphingolipid transporter activity
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.47	GO:0005765	lysosomal membrane
0.44	GO:0031982	vesicle
0.37	GO:0031966	mitochondrial membrane
0.37	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

tr|Q7ZU21|Q7ZU21_DANRE
Cyclin B1
Search

CCNB1

0.77

Cyclin B

0.50	GO:0001556	oocyte maturation
0.46	GO:2000775	histone H3-S10 phosphorylation involved in chromosome condensation
0.46	GO:0031662	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle
0.45	GO:1905448	positive regulation of mitochondrial ATP synthesis coupled electron transport
0.44	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore
0.44	GO:0048146	positive regulation of fibroblast proliferation
0.44	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint
0.43	GO:0007080	mitotic metaphase plate congression
0.43	GO:0007052	mitotic spindle organization
0.43	GO:0045931	positive regulation of mitotic cell cycle

0.46	GO:0005113	patched binding
0.44	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity
0.42	GO:0044389	ubiquitin-like protein ligase binding
0.42	GO:0019901	protein kinase binding
0.37	GO:0016301	kinase activity
0.31	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.31	GO:0140096	catalytic activity, acting on a protein

0.61	GO:0005634	nucleus
0.45	GO:0097125	cyclin B1-CDK1 complex
0.42	GO:0000940	condensed chromosome outer kinetochore
0.42	GO:0000922	spindle pole
0.42	GO:0005815	microtubule organizing center
0.41	GO:0005759	mitochondrial matrix
0.40	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.31

GO:0016773

sp|Q7ZU29|NUP93_DANRE
Nuclear pore complex protein Nup93
Search

NUP93

0.95	Nuclear pore complex protein Nup93

0.76	GO:0051028	mRNA transport
0.65	GO:0015031	protein transport
0.56	GO:0051292	nuclear pore complex assembly
0.55	GO:0090521	glomerular visceral epithelial cell migration
0.54	GO:0060391	positive regulation of SMAD protein import into nucleus
0.54	GO:0072015	glomerular visceral epithelial cell development
0.53	GO:1903206	negative regulation of hydrogen peroxide-induced cell death
0.52	GO:0060395	SMAD protein signal transduction
0.52	GO:0006998	nuclear envelope organization
0.45	GO:0071166	ribonucleoprotein complex localization

0.80	GO:0017056	structural constituent of nuclear pore
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.77	GO:0005643	nuclear pore
0.51	GO:0034399	nuclear periphery
0.51	GO:0031965	nuclear membrane
0.33	GO:0043657	host cell
0.30	GO:0044425	membrane part

tr|Q7ZU32|Q7ZU32_DANRE
Esr2a protein
Search

0.84	Estrogen receptor type II

0.85	GO:0030520	intracellular estrogen receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0043627	response to estrogen
0.36	GO:0032355	response to estradiol
0.36	GO:0051254	positive regulation of RNA metabolic process
0.36	GO:0044093	positive regulation of molecular function
0.36	GO:0010557	positive regulation of macromolecule biosynthetic process

0.85	GO:0030284	estrogen receptor activity
0.81	GO:0005496	steroid binding
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.49	GO:0042562	hormone binding
0.37	GO:0001047	core promoter binding
0.36	GO:0001012	RNA polymerase II regulatory region DNA binding
0.36	GO:0042802	identical protein binding
0.36	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.34	GO:0005739	mitochondrion
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

tr|Q7ZU33|Q7ZU33_DANRE
Casein kinase 2, alpha prime polypeptide a
Search

CSNK2A2

0.78	casein kinase II subunit alpha'

0.63	GO:0006468	protein phosphorylation
0.54	GO:1903146	regulation of autophagy of mitochondrion
0.54	GO:1903955	positive regulation of protein targeting to mitochondrion
0.52	GO:1905818	regulation of chromosome separation
0.38	GO:0097421	liver regeneration
0.38	GO:0016055	Wnt signaling pathway
0.37	GO:0021987	cerebral cortex development
0.37	GO:0007283	spermatogenesis
0.37	GO:0006915	apoptotic process
0.37	GO:0043666	regulation of phosphoprotein phosphatase activity

0.69	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0047485	protein N-terminus binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0008013	beta-catenin binding
0.37	GO:0019888	protein phosphatase regulator activity

0.53	GO:0031519	PcG protein complex
0.37	GO:0001669	acrosomal vesicle
0.36	GO:0000785	chromatin
0.34	GO:0005956	protein kinase CK2 complex
0.34	GO:0005886	plasma membrane
0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.69

GO:0004674

sp|Q7ZU42|OLA1_DANRE
Obg-like ATPase 1
Search

tr|Q7ZU43|Q7ZU43_DANRE
Carboxypeptidase, vitellogenic-like
Search

CPVL

0.47	Serine carboxypeptidase CPVL

0.61	GO:0006508	proteolysis
0.44	GO:0044257	cellular protein catabolic process

0.75

GO:0004185

serine-type carboxypeptidase activity

0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.75

EC:3.4.16

GO:0004185

sp|Q7ZU45|TTC25_DANRE
Tetratricopeptide repeat protein 25
Search

TTC25

0.96	Tetratricopeptide repeat protein 25

0.52	GO:0009214	cyclic nucleotide catabolic process
0.44	GO:0032474	otolith morphogenesis
0.42	GO:0061371	determination of heart left/right asymmetry
0.41	GO:0060271	cilium assembly
0.36	GO:0098869	cellular oxidant detoxification
0.34	GO:0055114	oxidation-reduction process
0.32	GO:0005975	carbohydrate metabolic process

0.50	GO:0004113	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity
0.38	GO:0004096	catalase activity
0.36	GO:0005515	protein binding
0.35	GO:0020037	heme binding
0.33	GO:0030246	carbohydrate binding
0.32	GO:0016853	isomerase activity

0.47	GO:0005737	cytoplasm
0.44	GO:0005856	cytoskeleton
0.44	GO:0042995	cell projection
0.30	GO:0016020	membrane

0.50

EC:3.1.4.37

GO:0004113

tr|Q7ZU46|Q7ZU46_DANRE
Heat shock protein 4, like
Search

0.90	Epididymis secretory sperm binding protein Li 5a

0.53	GO:0045040	protein import into mitochondrial outer membrane
0.52	GO:0051131	chaperone-mediated protein complex assembly
0.35	GO:0043392	negative regulation of DNA binding
0.34	GO:0032092	positive regulation of protein binding
0.34	GO:0045766	positive regulation of angiogenesis
0.34	GO:0006986	response to unfolded protein
0.34	GO:0001822	kidney development
0.34	GO:0043066	negative regulation of apoptotic process
0.34	GO:0009408	response to heat
0.34	GO:0001933	negative regulation of protein phosphorylation

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.33	GO:0044877	macromolecular complex binding
0.32	GO:0046872	metal ion binding

0.51	GO:0070062	extracellular exosome
0.46	GO:0005829	cytosol
0.34	GO:0005811	lipid droplet
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|Q7ZU53|Q7ZU53_DANRE
Cryptochrome 3
Search

CRY2

0.27	Cryptochrome circadian clock 2

0.76	GO:2000850	negative regulation of glucocorticoid secretion
0.76	GO:0009649	entrainment of circadian clock
0.75	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway
0.74	GO:0042754	negative regulation of circadian rhythm
0.71	GO:0032922	circadian regulation of gene expression
0.71	GO:0009648	photoperiodism
0.68	GO:0032868	response to insulin
0.68	GO:0019915	lipid storage
0.67	GO:0045892	negative regulation of transcription, DNA-templated
0.67	GO:0042593	glucose homeostasis

0.70	GO:0035257	nuclear hormone receptor binding
0.65	GO:0019901	protein kinase binding
0.64	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.62	GO:0071949	FAD binding
0.47	GO:0009881	photoreceptor activity
0.47	GO:0019902	phosphatase binding
0.44	GO:0000989	transcription factor activity, transcription factor binding
0.42	GO:0003914	DNA (6-4) photolyase activity
0.40	GO:0003904	deoxyribodipyrimidine photo-lyase activity
0.40	GO:0003697	single-stranded DNA binding

0.65	GO:0016607	nuclear speck
0.62	GO:0005829	cytosol
0.57	GO:0097381	photoreceptor disc membrane
0.56	GO:0042622	photoreceptor outer segment membrane
0.52	GO:0005739	mitochondrion
0.51	GO:0005667	transcription factor complex
0.37	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.42

EC:4.1.99.13

GO:0003914

tr|Q7ZU67|Q7ZU67_DANRE
Eukaryotic translation initiation factor 4A, isoform 1B
Search

EIF4A1

0.87	Eukaryotic initiation factor 4A-II

0.72	GO:0006413	translational initiation
0.51	GO:1900260	negative regulation of RNA-directed 5'-3' RNA polymerase activity
0.49	GO:0010501	RNA secondary structure unwinding
0.47	GO:1990823	response to leukemia inhibitory factor
0.45	GO:0071345	cellular response to cytokine stimulus
0.39	GO:0010468	regulation of gene expression
0.35	GO:0006401	RNA catabolic process
0.35	GO:0016926	protein desumoylation
0.34	GO:0016071	mRNA metabolic process
0.34	GO:0016032	viral process

0.78	GO:0004004	ATP-dependent RNA helicase activity
0.72	GO:0003743	translation initiation factor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0003725	double-stranded RNA binding
0.34	GO:0005515	protein binding
0.34	GO:0000339	RNA cap binding
0.34	GO:0003729	mRNA binding
0.33	GO:0008234	cysteine-type peptidase activity

0.45	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0005730	nucleolus
0.36	GO:0016281	eukaryotic translation initiation factor 4F complex
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.34	GO:0071339	MLL1 complex
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008234

tr|Q7ZU69|Q7ZU69_DANRE
Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 13
Search

PSMD13

0.90	26S proteasome non-ATPase regulatory subunit 13

0.52	GO:0007127	meiosis I
0.48	GO:0043248	proteasome assembly
0.47	GO:0030097	hemopoiesis
0.45	GO:0006511	ubiquitin-dependent protein catabolic process
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.36	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.36	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation

0.41	GO:0005198	structural molecule activity
0.33	GO:0004175	endopeptidase activity

0.69	GO:1905369	endopeptidase complex
0.57	GO:0043234	protein complex
0.44	GO:0005829	cytosol
0.41	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.36	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.30	GO:0016020	membrane

tr|Q7ZU70|Q7ZU70_DANRE
Tripartite motif-containing 47
Search

0.82	Tripartite motif-containing 47

0.49	GO:0006914	autophagy
0.49	GO:0016567	protein ubiquitination
0.44	GO:0045087	innate immune response
0.43	GO:0032880	regulation of protein localization
0.41	GO:0051607	defense response to virus
0.41	GO:0048525	negative regulation of viral process
0.40	GO:1902186	regulation of viral release from host cell
0.40	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.40	GO:0046596	regulation of viral entry into host cell
0.40	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway

0.62	GO:0008270	zinc ion binding
0.49	GO:0004842	ubiquitin-protein transferase activity
0.44	GO:0030674	protein binding, bridging
0.40	GO:0008329	signaling pattern recognition receptor activity
0.40	GO:0016874	ligase activity
0.36	GO:0019901	protein kinase binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0019904	protein domain specific binding
0.36	GO:0061659	ubiquitin-like protein ligase activity
0.35	GO:0008134	transcription factor binding

0.44	GO:0005622	intracellular
0.36	GO:0043227	membrane-bounded organelle
0.35	GO:1990904	ribonucleoprotein complex
0.35	GO:0043228	non-membrane-bounded organelle
0.35	GO:0012505	endomembrane system
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.40	EC:6	GO:0016874
0.49	KEGG:R03876	GO:0004842

tr|Q7ZU79|Q7ZU79_DANRE
CDC45 cell division cycle 45 homolog (S. cerevisiae)
Search

CDC45

0.93	Cell division control protein 45

0.75	GO:0006270	DNA replication initiation
0.55	GO:0051301	cell division
0.50	GO:1902977	mitotic DNA replication preinitiation complex assembly
0.49	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.49	GO:1902299	pre-replicative complex assembly involved in cell cycle DNA replication
0.49	GO:0031938	regulation of chromatin silencing at telomere
0.49	GO:0000727	double-strand break repair via break-induced replication
0.43	GO:0032392	DNA geometric change
0.35	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle
0.35	GO:0000076	DNA replication checkpoint

0.47	GO:0043138	3'-5' DNA helicase activity
0.46	GO:0003682	chromatin binding
0.46	GO:0003688	DNA replication origin binding
0.45	GO:0003697	single-stranded DNA binding
0.35	GO:0008270	zinc ion binding
0.34	GO:0005515	protein binding

0.49	GO:0005813	centrosome
0.49	GO:0005656	nuclear pre-replicative complex
0.48	GO:0031298	replication fork protection complex
0.48	GO:0031261	DNA replication preinitiation complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q7ZU80|LNPA_DANRE
Protein lunapark-A
Search

LNPK

0.96	Endoplasmic reticulum junction formation protein lunapark-A

0.57	GO:0071788	endoplasmic reticulum tubular network maintenance
0.56	GO:1903373	positive regulation of endoplasmic reticulum tubular network organization
0.51	GO:0035115	embryonic forelimb morphogenesis
0.50	GO:0032330	regulation of chondrocyte differentiation
0.50	GO:0042733	embryonic digit morphogenesis
0.49	GO:0007596	blood coagulation

0.48	GO:0042802	identical protein binding
0.36	GO:0046872	metal ion binding

0.55	GO:0098826	endoplasmic reticulum tubular network membrane
0.50	GO:0030176	integral component of endoplasmic reticulum membrane
0.44	GO:0005654	nucleoplasm

tr|Q7ZU89|Q7ZU89_DANRE
Coatomer subunit delta
Search

ARCN1

0.68	Coatomer subunit delta

0.81	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.65	GO:0015031	protein transport
0.55	GO:0021691	cerebellar Purkinje cell layer maturation
0.51	GO:0008344	adult locomotory behavior
0.51	GO:0043473	pigmentation
0.34	GO:0006891	intra-Golgi vesicle-mediated transport
0.34	GO:0006888	ER to Golgi vesicle-mediated transport
0.33	GO:0034613	cellular protein localization
0.30	GO:0008152	metabolic process

0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.30	GO:0003824	catalytic activity

0.80	GO:0030126	COPI vesicle coat
0.73	GO:0000139	Golgi membrane
0.46	GO:0005783	endoplasmic reticulum
0.34	GO:0030133	transport vesicle
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0005829	cytosol

sp|Q7ZU90|CHD1L_DANRE
Chromodomain-helicase-DNA-binding protein 1-like
Search

CHD1L

0.92	Chromodomain helicase DNA binding protein 1 like

0.76	GO:0006338	chromatin remodeling
0.68	GO:0032392	DNA geometric change
0.63	GO:0006974	cellular response to DNA damage stimulus
0.58	GO:0006259	DNA metabolic process

0.70	GO:0004003	ATP-dependent DNA helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0005654	nucleoplasm
0.54	GO:0005829	cytosol
0.46	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q7ZU91|ITPK1_DANRE
Inositol-tetrakisphosphate 1-kinase
Search

ITPK1

0.77	Inositol-tetrakisphosphate 1-kinase a

0.85	GO:0032957	inositol trisphosphate metabolic process
0.57	GO:0016310	phosphorylation
0.51	GO:0021915	neural tube development
0.34	GO:0007596	blood coagulation
0.33	GO:0016311	dephosphorylation
0.33	GO:0007165	signal transduction

0.85	GO:0052726	inositol-1,3,4-trisphosphate 5-kinase activity
0.85	GO:0047325	inositol tetrakisphosphate 1-kinase activity
0.85	GO:0052725	inositol-1,3,4-trisphosphate 6-kinase activity
0.64	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0016853	isomerase activity
0.36	GO:0052831	inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity
0.36	GO:0052830	inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity

0.51	GO:0016324	apical plasma membrane
0.45	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.85	EC:2.7.1.159	GO:0052726
0.85	KEGG:R03428	GO:0052726

sp|Q7ZU92|PARN_DANRE
Poly(A)-specific ribonuclease PARN
Search

PARN

0.91	Poly(A)-specific ribonuclease (deadenylation nuclease)

0.73	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.72	GO:0006402	mRNA catabolic process
0.59	GO:0110008	ncRNA deadenylation
0.58	GO:0090669	telomerase RNA stabilization
0.56	GO:1904872	regulation of telomerase RNA localization to Cajal body
0.56	GO:0051973	positive regulation of telomerase activity
0.55	GO:0032212	positive regulation of telomere maintenance via telomerase
0.35	GO:0030097	hemopoiesis
0.35	GO:0022414	reproductive process
0.35	GO:0043488	regulation of mRNA stability

0.83	GO:0004535	poly(A)-specific ribonuclease activity
0.57	GO:0003723	RNA binding
0.52	GO:0046872	metal ion binding
0.52	GO:0019901	protein kinase binding

0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.34	GO:0043233	organelle lumen
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0044446	intracellular organelle part

0.83

EC:3.1.13.4

GO:0004535

tr|Q7ZU93|Q7ZU93_DANRE
SNU13 homolog, small nuclear ribonucleoprotein a (U4/U6.U5)
Search

SNU13

0.96	Small nuclear ribonucleoprotein 13

0.67	GO:0042254	ribosome biogenesis
0.50	GO:0000492	box C/D snoRNP assembly
0.48	GO:0007338	single fertilization
0.44	GO:0008380	RNA splicing
0.43	GO:0006397	mRNA processing
0.42	GO:0016072	rRNA metabolic process
0.41	GO:0034470	ncRNA processing
0.40	GO:0043043	peptide biosynthetic process
0.38	GO:0044267	cellular protein metabolic process
0.38	GO:0009059	macromolecule biosynthetic process

0.59	GO:0003723	RNA binding
0.50	GO:0051117	ATPase binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0016787	hydrolase activity

0.73	GO:0005730	nucleolus
0.61	GO:0030529	intracellular ribonucleoprotein complex
0.45	GO:0120114	Sm-like protein family complex
0.43	GO:0044445	cytosolic part
0.40	GO:0043234	protein complex
0.33	GO:0005654	nucleoplasm
0.32	GO:0005886	plasma membrane

0.33

GO:0016787

tr|Q7ZU97|Q7ZU97_DANRE
Zfand5b protein
Search

ZFAND5

0.94	Zinc finger A20 domain-containing protein 2

0.55	GO:0010761	fibroblast migration
0.55	GO:0003016	respiratory system process
0.54	GO:0048745	smooth muscle tissue development
0.53	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.53	GO:0060324	face development
0.51	GO:0048705	skeletal system morphogenesis
0.50	GO:0001944	vasculature development
0.48	GO:0001701	in utero embryonic development

0.63	GO:0008270	zinc ion binding
0.54	GO:0003677	DNA binding
0.33	GO:0005515	protein binding

0.33

GO:0005737

cytoplasm

sp|Q7ZU99|TERA_DANRE
Transitional endoplasmic reticulum ATPase
Search

VCP

0.77	Transitional endoplasmic reticulum ATPase

0.59	GO:0061857	endoplasmic reticulum stress-induced pre-emptive quality control
0.58	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway
0.57	GO:1903007	positive regulation of Lys63-specific deubiquitinase activity
0.57	GO:0042728	flavin-containing compound catabolic process
0.57	GO:0070842	aggresome assembly
0.56	GO:2000158	positive regulation of ubiquitin-specific protease activity
0.56	GO:0034214	protein hexamerization
0.56	GO:0010918	positive regulation of mitochondrial membrane potential
0.56	GO:0097352	autophagosome maturation
0.56	GO:1903862	positive regulation of oxidative phosphorylation

0.56	GO:0035800	deubiquitinase activator activity
0.56	GO:1904288	BAT3 complex binding
0.56	GO:0036435	K48-linked polyubiquitin modification-dependent protein binding
0.55	GO:0042288	MHC class I protein binding
0.55	GO:1990381	ubiquitin-specific protease binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0019903	protein phosphatase binding

0.57	GO:1990730	VCP-NSFL1C complex
0.55	GO:0036513	Derlin-1 retrotranslocation complex
0.55	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex
0.54	GO:0035861	site of double-strand break
0.52	GO:0043209	myelin sheath
0.52	GO:0005811	lipid droplet
0.50	GO:0048471	perinuclear region of cytoplasm
0.48	GO:1905369	endopeptidase complex
0.48	GO:0005829	cytosol
0.47	GO:0005654	nucleoplasm

0.50

GO:0016787

tr|Q7ZUB0|Q7ZUB0_DANRE
Atrial myosin light chain
Search

MYL4

0.89	Myosin essential light chain fast

0.53	GO:0006936	muscle contraction
0.50	GO:0060047	heart contraction
0.50	GO:0002026	regulation of the force of heart contraction
0.47	GO:0032781	positive regulation of ATPase activity
0.38	GO:0055005	ventricular cardiac myofibril assembly
0.38	GO:0003007	heart morphogenesis
0.37	GO:0045214	sarcomere organization
0.37	GO:0033275	actin-myosin filament sliding
0.35	GO:0003229	ventricular cardiac muscle tissue development
0.35	GO:0060415	muscle tissue morphogenesis

0.70	GO:0005509	calcium ion binding
0.49	GO:0003785	actin monomer binding
0.46	GO:0051015	actin filament binding
0.35	GO:0032038	myosin II heavy chain binding
0.34	GO:0008307	structural constituent of muscle

0.53	GO:0030016	myofibril
0.48	GO:0044449	contractile fiber part
0.38	GO:0016459	myosin complex
0.34	GO:0005829	cytosol

sp|Q7ZUB3|TSN31_DANRE
Tetraspanin-31
Search

TSPAN31

0.48	Tetraspanin

0.47	GO:1903169	regulation of calcium ion transmembrane transport
0.44	GO:0007166	cell surface receptor signaling pathway
0.42	GO:0065009	regulation of molecular function
0.34	GO:0008284	positive regulation of cell proliferation

0.48	GO:0005246	calcium channel regulator activity
0.33	GO:0005515	protein binding

0.43

GO:0005887

integral component of plasma membrane

tr|Q7ZUB6|Q7ZUB6_DANRE
Fetal brain protein 239
Search

MPPED2

0.97	Metallophosphoesterase domain-containing protein 2

0.37	GO:0072015	glomerular visceral epithelial cell development
0.34	GO:0007399	nervous system development

0.50	GO:0016787	hydrolase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.30

GO:0016020

membrane

0.50

GO:0016787

tr|Q7ZUC1|Q7ZUC1_DANRE
Vesicle-associated membrane protein 8 (Endobrevin)
Search

VAMP8

0.97	Non-SMC condensin I complex, subunit H

0.69	GO:0016192	vesicle-mediated transport
0.61	GO:0070254	mucus secretion
0.61	GO:1903595	positive regulation of histamine secretion by mast cell
0.60	GO:0016240	autophagosome membrane docking
0.56	GO:1903076	regulation of protein localization to plasma membrane
0.56	GO:1903531	negative regulation of secretion by cell
0.49	GO:0090174	organelle membrane fusion
0.48	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.48	GO:0044409	entry into host
0.48	GO:0016050	vesicle organization

0.59	GO:0019869	chloride channel inhibitor activity
0.49	GO:0000149	SNARE binding
0.48	GO:0005484	SNAP receptor activity

0.61	GO:0098594	mucin granule
0.60	GO:0035577	azurophil granule membrane
0.58	GO:0031201	SNARE complex
0.56	GO:0031902	late endosome membrane
0.55	GO:0055037	recycling endosome
0.54	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0005829	cytosol
0.48	GO:0008021	synaptic vesicle
0.43	GO:0005886	plasma membrane
0.42	GO:0031901	early endosome membrane

sp|Q7ZUC2|CAB45_DANRE
45 kDa calcium-binding protein
Search

SDF4

0.54	Stromal cell derived factor 4

0.53	GO:0045444	fat cell differentiation
0.45	GO:0002040	sprouting angiogenesis
0.39	GO:0009650	UV protection
0.38	GO:0070625	zymogen granule exocytosis
0.38	GO:0045471	response to ethanol
0.38	GO:0021549	cerebellum development

0.70	GO:0005509	calcium ion binding
0.35	GO:0042802	identical protein binding

0.57	GO:0005796	Golgi lumen
0.51	GO:0005770	late endosome
0.36	GO:0070062	extracellular exosome
0.35	GO:0032059	bleb
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q7ZUC4|Q7ZUC4_DANRE
Ccdc6a protein
Search

CCDC6

0.95	LOW QUALITY PROTEIN: coiled-coil domain-containing protein 6

0.44	GO:0007165	signal transduction
0.39	GO:0055085	transmembrane transport
0.37	GO:0007010	cytoskeleton organization
0.36	GO:0018108	peptidyl-tyrosine phosphorylation

0.42	GO:0017124	SH3 domain binding
0.38	GO:0005200	structural constituent of cytoskeleton
0.36	GO:0004713	protein tyrosine kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.62	GO:0005829	cytosol
0.40	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane

0.36

GO:0004713

tr|Q7ZUC5|Q7ZUC5_DANRE
Protein kinase C delta type
Search

PRKCD

0.97	Protein kinase C delta type

0.66	GO:0006915	apoptotic process
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.58	GO:2000753	positive regulation of glucosylceramide catabolic process
0.58	GO:2000755	positive regulation of sphingomyelin catabolic process
0.57	GO:1900163	positive regulation of phospholipid scramblase activity
0.57	GO:0007049	cell cycle
0.57	GO:0023021	termination of signal transduction
0.57	GO:2000304	positive regulation of ceramide biosynthetic process
0.56	GO:0051490	negative regulation of filopodium assembly

0.83	GO:0004697	protein kinase C activity
0.55	GO:0043560	insulin receptor substrate binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.50	GO:0019901	protein kinase binding
0.49	GO:0008047	enzyme activator activity
0.37	GO:0004715	non-membrane spanning protein tyrosine kinase activity

0.66	GO:0048471	perinuclear region of cytoplasm
0.54	GO:0005634	nucleus
0.49	GO:0005911	cell-cell junction
0.47	GO:0005783	endoplasmic reticulum
0.46	GO:0005829	cytosol
0.45	GO:0070013	intracellular organelle lumen
0.41	GO:0044446	intracellular organelle part
0.41	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0042582	azurophil granule

0.83

EC:2.7.11.13

GO:0004697

tr|Q7ZUC6|Q7ZUC6_DANRE
Suppressor of cytokine signaling 3a
Search

SOCS3

0.96	Suppressor of cytokine signaling 3

0.80	GO:0007259	JAK-STAT cascade
0.73	GO:0043066	negative regulation of apoptotic process
0.66	GO:0016567	protein ubiquitination
0.59	GO:0046426	negative regulation of JAK-STAT cascade
0.55	GO:0046627	negative regulation of insulin receptor signaling pathway
0.52	GO:0071345	cellular response to cytokine stimulus
0.52	GO:0060708	spongiotrophoblast differentiation
0.52	GO:0032102	negative regulation of response to external stimulus
0.52	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation
0.52	GO:0042509	regulation of tyrosine phosphorylation of STAT protein

0.52	GO:0001784	phosphotyrosine residue binding
0.47	GO:0004860	protein kinase inhibitor activity
0.45	GO:0008269	JAK pathway signal transduction adaptor activity
0.44	GO:0005159	insulin-like growth factor receptor binding
0.33	GO:0017124	SH3 domain binding

0.45	GO:0005622	intracellular
0.32	GO:0043227	membrane-bounded organelle
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q7ZUC7|PGES2_DANRE
Prostaglandin E synthase 2
Search

PTGES2

0.94	Prostaglandin E synthase 2

0.67	GO:0045454	cell redox homeostasis
0.60	GO:0022900	electron transport chain
0.47	GO:0045893	positive regulation of transcription, DNA-templated
0.45	GO:0046903	secretion
0.41	GO:0046457	prostanoid biosynthetic process
0.41	GO:0006693	prostaglandin metabolic process
0.35	GO:0002283	neutrophil activation involved in immune response
0.35	GO:0002446	neutrophil mediated immunity
0.35	GO:0019369	arachidonic acid metabolic process
0.33	GO:0016192	vesicle-mediated transport

0.85	GO:0050220	prostaglandin-E synthase activity
0.71	GO:0015035	protein disulfide oxidoreductase activity
0.61	GO:0009055	electron transfer activity
0.41	GO:0043295	glutathione binding
0.40	GO:0003677	DNA binding
0.36	GO:0020037	heme binding
0.36	GO:0016829	lyase activity
0.34	GO:0016740	transferase activity
0.33	GO:0005515	protein binding

0.45	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.42	GO:0005634	nucleus
0.38	GO:0000139	Golgi membrane
0.36	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0035578	azurophil granule lumen
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.85	EC:5.3.99.3	GO:0050220
0.85	KEGG:R02265	GO:0050220

tr|Q7ZUC9|Q7ZUC9_DANRE
SH3 domain binding glutamic acid-rich protein like 3
Search

0.77	SH3 domain binding glutamate-rich protein like

0.68	GO:0045454	cell redox homeostasis
0.60	GO:0022900	electron transport chain

0.72	GO:0015035	protein disulfide oxidoreductase activity
0.61	GO:0009055	electron transfer activity

0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|Q7ZUD8|Q7ZUD8_DANRE
Map1lc3b protein
Search

MAP1LC3B

0.83	RNA-dependent DNA polymerase

0.77	GO:0006914	autophagy
0.52	GO:0061726	mitochondrion disassembly
0.51	GO:0070257	positive regulation of mucus secretion
0.51	GO:0006995	cellular response to nitrogen starvation
0.50	GO:0007033	vacuole organization
0.47	GO:0070925	organelle assembly
0.41	GO:0043241	protein complex disassembly
0.36	GO:0010288	response to lead ion
0.36	GO:0071280	cellular response to copper ion
0.36	GO:0043278	response to morphine

0.43	GO:0031625	ubiquitin protein ligase binding
0.42	GO:0008429	phosphatidylethanolamine binding
0.35	GO:0008017	microtubule binding
0.34	GO:0019904	protein domain specific binding

0.56	GO:0005776	autophagosome
0.53	GO:0005767	secondary lysosome
0.49	GO:0005774	vacuolar membrane
0.48	GO:0005930	axoneme
0.47	GO:0005829	cytosol
0.39	GO:0005874	microtubule
0.38	GO:0031410	cytoplasmic vesicle
0.37	GO:0012505	endomembrane system
0.35	GO:0005739	mitochondrion
0.34	GO:0043025	neuronal cell body

tr|Q7ZUE4|Q7ZUE4_DANRE
PRP40 pre-mRNA processing factor 40 homolog A (Yeast)
Search

PRPF40A

0.88	Pre-mRNA-processing factor 40 like protein A

0.72	GO:0032465	regulation of cytokinesis
0.71	GO:0016477	cell migration
0.66	GO:0007010	cytoskeleton organization
0.64	GO:0008360	regulation of cell shape
0.59	GO:0000398	mRNA splicing, via spliceosome
0.35	GO:0051301	cell division
0.35	GO:0007049	cell cycle

0.81	GO:0070064	proline-rich region binding
0.48	GO:0003723	RNA binding

0.78	GO:0016363	nuclear matrix
0.74	GO:0016607	nuclear speck
0.64	GO:0071004	U2-type prespliceosome
0.63	GO:0005829	cytosol
0.63	GO:0005685	U1 snRNP
0.30	GO:0016020	membrane

sp|Q7ZUF2|BRD9_DANRE
Bromodomain-containing protein 9
Search

BRD9

0.97	Bromodomain-containing protein 9

0.49	GO:0016569	covalent chromatin modification
0.42	GO:0097659	nucleic acid-templated transcription
0.42	GO:2001141	regulation of RNA biosynthetic process
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.42	GO:0010468	regulation of gene expression
0.41	GO:0010467	gene expression
0.40	GO:0034645	cellular macromolecule biosynthetic process

0.84	GO:0140033	acetylation-dependent protein binding
0.79	GO:0042393	histone binding
0.34	GO:0003676	nucleic acid binding

0.30

GO:0031224

intrinsic component of membrane

tr|Q7ZUF3|Q7ZUF3_DANRE
Ube2h protein
Search

UBE2H

0.92	Ubiquitin-conjugating enzyme E2H

0.47	GO:0006511	ubiquitin-dependent protein catabolic process
0.47	GO:0016567	protein ubiquitination
0.45	GO:0010498	proteasomal protein catabolic process

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0061631	ubiquitin conjugating enzyme activity
0.47	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0061630	ubiquitin protein ligase activity

0.37

GO:0005737

cytoplasm

tr|Q7ZUF8|Q7ZUF8_DANRE
Zgc:56699
Search

GTSF1

0.93	Gametocyte-specific factor 1

0.75	GO:0007283	spermatogenesis
0.37	GO:0030154	cell differentiation
0.36	GO:0007229	integrin-mediated signaling pathway
0.35	GO:0007155	cell adhesion
0.33	GO:0007275	multicellular organism development

0.35	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.38	GO:0005737	cytoplasm
0.36	GO:0008305	integrin complex

tr|Q7ZUF9|Q7ZUF9_DANRE
Zgc:56688
Search

ZNHIT3

0.95	Zinc finger HIT domain-containing protein 3

0.35	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:0010468	regulation of gene expression

0.51	GO:0046872	metal ion binding
0.35	GO:0046966	thyroid hormone receptor binding
0.35	GO:0004930	G-protein coupled receptor activity
0.32	GO:0003676	nucleic acid binding

0.42	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q7ZUG0|RUXE_DANRE
Small nuclear ribonucleoprotein E
Search

SNRPE

0.84	Small nuclear ribonucleoprotein polypeptide E

0.75	GO:0000398	mRNA splicing, via spliceosome
0.46	GO:0022618	ribonucleoprotein complex assembly
0.43	GO:0042633	hair cycle
0.35	GO:0008334	histone mRNA metabolic process
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0051170	nuclear import
0.34	GO:0070588	calcium ion transmembrane transport
0.33	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.36	GO:0003723	RNA binding
0.35	GO:1990446	U1 snRNP binding
0.34	GO:0005388	calcium-transporting ATPase activity
0.33	GO:0005515	protein binding
0.33	GO:0043565	sequence-specific DNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.76	GO:0005681	spliceosomal complex
0.58	GO:0019013	viral nucleocapsid
0.51	GO:0005687	U4 snRNP
0.49	GO:0005685	U1 snRNP
0.48	GO:0005682	U5 snRNP
0.48	GO:0005686	U2 snRNP
0.47	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.45	GO:0034709	methylosome
0.45	GO:0034715	pICln-Sm protein complex
0.45	GO:0034719	SMN-Sm protein complex

0.34

EC:3.6.3.8

GO:0005388

tr|Q7ZUG4|Q7ZUG4_DANRE
RAB5A, member RAS oncogene family like
Search

RAB5A

0.96	Member RAS oncogene family

0.54	GO:0051489	regulation of filopodium assembly
0.53	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway
0.51	GO:0051036	regulation of endosome size
0.51	GO:0060627	regulation of vesicle-mediated transport
0.51	GO:0045056	transcytosis
0.50	GO:0045022	early endosome to late endosome transport
0.50	GO:0098693	regulation of synaptic vesicle cycle
0.50	GO:0046928	regulation of neurotransmitter secretion
0.50	GO:0036465	synaptic vesicle recycling
0.48	GO:1903532	positive regulation of secretion by cell

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.50	GO:0019003	GDP binding
0.35	GO:0051021	GDP-dissociation inhibitor binding
0.34	GO:0004402	histone acetyltransferase activity
0.32	GO:0046872	metal ion binding

0.53	GO:0005769	early endosome
0.53	GO:0030139	endocytic vesicle
0.52	GO:0001726	ruffle
0.51	GO:0010009	cytoplasmic side of endosome membrane
0.50	GO:0098857	membrane microdomain
0.50	GO:0043195	terminal bouton
0.47	GO:0036477	somatodendritic compartment
0.47	GO:0015629	actin cytoskeleton
0.44	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane

0.34

GO:0004402

sp|Q7ZUG5|RS21_DANRE
40S ribosomal protein S21
Search

RPS21

0.71	Ribosomal protein S21

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.44	GO:0042274	ribosomal small subunit biogenesis
0.43	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.43	GO:0016072	rRNA metabolic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0048542	lymph gland development
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.63	GO:0003735	structural constituent of ribosome
0.51	GO:0047485	protein N-terminus binding
0.37	GO:0043022	ribosome binding
0.33	GO:0003723	RNA binding

0.60	GO:0005840	ribosome
0.52	GO:0005844	polysome
0.49	GO:0044445	cytosolic part
0.43	GO:0044446	intracellular organelle part
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0043233	organelle lumen
0.33	GO:0005634	nucleus

tr|Q7ZUG6|Q7ZUG6_DANRE
Ribosomal protein L30
Search

RPL30

0.76	Ribosomal protein L30

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.46	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.44	GO:0050829	defense response to Gram-negative bacterium
0.43	GO:0031640	killing of cells of other organism
0.36	GO:1904571	positive regulation of selenocysteine incorporation
0.35	GO:0097421	liver regeneration
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

0.64	GO:0003735	structural constituent of ribosome
0.39	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.45	GO:0044445	cytosolic part
0.43	GO:0005844	polysome
0.40	GO:0044446	intracellular organelle part
0.38	GO:0005634	nucleus
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

tr|Q7ZUG7|Q7ZUG7_DANRE
Zgc:56628
Search

LMO4

0.97	LOW QUALITY PROTEIN: LIM domain transcription factor LMO4

0.55	GO:0021527	spinal cord association neuron differentiation
0.54	GO:0021514	ventral spinal cord interneuron differentiation
0.53	GO:0042659	regulation of cell fate specification
0.53	GO:0021522	spinal cord motor neuron differentiation
0.53	GO:0048538	thymus development
0.53	GO:0003281	ventricular septum development
0.53	GO:0001843	neural tube closure
0.51	GO:0031333	negative regulation of protein complex assembly
0.50	GO:0030334	regulation of cell migration
0.50	GO:0033674	positive regulation of kinase activity

0.54	GO:0046872	metal ion binding
0.53	GO:0001158	enhancer sequence-specific DNA binding
0.47	GO:0008134	transcription factor binding
0.37	GO:0003712	transcription cofactor activity
0.33	GO:0003700	DNA binding transcription factor activity

0.51	GO:0031252	cell leading edge
0.48	GO:0005667	transcription factor complex

sp|Q7ZUH1|CN166_DANRE
UPF0568 protein C14orf166 homolog
Search

RTRAF

0.96	RNA transcription, translation and transport factor protein

0.77	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.76	GO:0006469	negative regulation of protein kinase activity
0.71	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:0006351	transcription, DNA-templated
0.39	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:0051236	establishment of RNA localization
0.38	GO:0050657	nucleic acid transport
0.36	GO:0016032	viral process

0.81	GO:0000993	RNA polymerase II core binding
0.69	GO:0042802	identical protein binding
0.57	GO:0003723	RNA binding
0.39	GO:0003677	DNA binding
0.38	GO:0004871	signal transducer activity

0.82	GO:0072669	tRNA-splicing ligase complex
0.77	GO:0072686	mitotic spindle
0.75	GO:0048471	perinuclear region of cytoplasm
0.74	GO:0005813	centrosome
0.66	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.42	GO:1905360	GTPase complex
0.41	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.38	GO:0098797	plasma membrane protein complex

sp|Q7ZUH5|RM14_DANRE
39S ribosomal protein L14, mitochondrial
Search

MRPL14

0.96	Mitochondrial ribosomal protein L14

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.50	GO:0005759	mitochondrial matrix
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q7ZUH8|Q7ZUH8_DANRE
Microsomal glutathione S-transferase 3a
Search

MGST3

0.87	Microsomal glutathione S-transferase

0.52	GO:0019370	leukotriene biosynthetic process
0.46	GO:0098869	cellular oxidant detoxification
0.43	GO:0006629	lipid metabolic process
0.37	GO:0010243	response to organonitrogen compound
0.35	GO:1901685	glutathione derivative metabolic process
0.34	GO:0006805	xenobiotic metabolic process
0.33	GO:0044272	sulfur compound biosynthetic process
0.32	GO:1901566	organonitrogen compound biosynthetic process
0.32	GO:0055114	oxidation-reduction process

0.54	GO:0004464	leukotriene-C4 synthase activity
0.50	GO:0004602	glutathione peroxidase activity
0.48	GO:0016740	transferase activity
0.33	GO:0005515	protein binding

0.43	GO:0005635	nuclear envelope
0.41	GO:0005783	endoplasmic reticulum
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0070062	extracellular exosome
0.35	GO:0031984	organelle subcompartment
0.34	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.54	EC:4.4.1.20	GO:0004464
0.54	KEGG:R03059	GO:0004464

tr|Q7ZUI0|Q7ZUI0_DANRE
Ribosomal protein L5a
Search

0.62	Ribosomal protein L5

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.48	GO:0000027	ribosomal large subunit assembly
0.47	GO:2000435	negative regulation of protein neddylation
0.45	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.45	GO:1904667	negative regulation of ubiquitin protein ligase activity
0.45	GO:1901796	regulation of signal transduction by p53 class mediator
0.43	GO:0050821	protein stabilization

0.79	GO:0008097	5S rRNA binding
0.64	GO:0003735	structural constituent of ribosome
0.46	GO:1990948	ubiquitin ligase inhibitor activity
0.44	GO:0003730	mRNA 3'-UTR binding
0.43	GO:0048027	mRNA 5'-UTR binding
0.43	GO:0031625	ubiquitin protein ligase binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.45	GO:0005829	cytosol
0.43	GO:0005730	nucleolus
0.41	GO:0005783	endoplasmic reticulum
0.40	GO:0005654	nucleoplasm
0.38	GO:0043234	protein complex
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.32

GO:0016787

tr|Q7ZUI3|Q7ZUI3_DANRE
Tetratricopeptide repeat domain 9C
Search

TTC9C

0.97	tetratricopeptide repeat protein 9C

0.81	GO:0032474	otolith morphogenesis
0.75	GO:0061371	determination of heart left/right asymmetry
0.71	GO:0060271	cilium assembly
0.43	GO:0060348	bone development
0.36	GO:0000413	protein peptidyl-prolyl isomerization

0.44	GO:0016853	isomerase activity
0.37	GO:0005515	protein binding
0.34	GO:0140096	catalytic activity, acting on a protein

0.30

GO:0031224

intrinsic component of membrane

0.44

GO:0016853

tr|Q7ZUI4|Q7ZUI4_DANRE
Thioredoxin
Search

0.47	Thioredoxin

0.69	GO:0006662	glycerol ether metabolic process
0.69	GO:0045454	cell redox homeostasis
0.49	GO:0055114	oxidation-reduction process
0.39	GO:0034599	cellular response to oxidative stress
0.38	GO:0098869	cellular oxidant detoxification
0.37	GO:0046822	regulation of nucleocytoplasmic transport
0.37	GO:0051223	regulation of protein transport
0.36	GO:0051457	maintenance of protein location in nucleus
0.36	GO:1904950	negative regulation of establishment of protein localization
0.36	GO:0051051	negative regulation of transport

0.66	GO:0015035	protein disulfide oxidoreductase activity
0.41	GO:0047134	protein-disulfide reductase activity
0.40	GO:0004791	thioredoxin-disulfide reductase activity
0.40	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
0.36	GO:0015037	peptide disulfide oxidoreductase activity
0.34	GO:0018024	histone-lysine N-methyltransferase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0016853	isomerase activity
0.32	GO:0003677	DNA binding
0.32	GO:0016787	hydrolase activity

0.35	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.34	GO:0005694	chromosome
0.34	GO:0106068	SUMO ligase complex
0.33	GO:0005576	extracellular region
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.41	EC:1.8.1.8	GO:0047134
0.40	KEGG:R02016	GO:0004791

tr|Q7ZUI8|Q7ZUI8_DANRE
Eukaryotic translation initiation factor 1B
Search

EIF1B

0.94	Eukaryotic translation initiation factor 1

0.72	GO:0006413	translational initiation
0.47	GO:0006446	regulation of translational initiation
0.44	GO:0009048	dosage compensation by inactivation of X chromosome
0.34	GO:0006886	intracellular protein transport

0.73	GO:0003743	translation initiation factor activity
0.35	GO:0017137	Rab GTPase binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0016787	hydrolase activity

0.41	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.32

GO:0016787

tr|Q7ZUJ8|Q7ZUJ8_DANRE
Proteasome subunit beta type
Search

PSMB3

0.54	Proteasome subunit beta type

0.76	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0070498	interleukin-1-mediated signaling pathway
0.35	GO:0038061	NIK/NF-kappaB signaling

0.76	GO:0070003	threonine-type peptidase activity
0.64	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding

0.81	GO:0019774	proteasome core complex, beta-subunit complex
0.57	GO:0005634	nucleus
0.46	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

sp|Q7ZUK0|RN146_DANRE
E3 ubiquitin-protein ligase rnf146
Search

RNF146

0.87	Ring finger protein 146

0.77	GO:0016055	Wnt signaling pathway
0.73	GO:0016567	protein ubiquitination
0.58	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.52	GO:0006511	ubiquitin-dependent protein catabolic process

0.86	GO:0072572	poly-ADP-D-ribose binding
0.76	GO:0061630	ubiquitin protein ligase activity
0.63	GO:0008270	zinc ion binding

0.50	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane

sp|Q7ZUK7|WAC_DANRE
WW domain-containing adapter protein with coiled-coil
Search

WAC

0.90	WW domain-containing adapter protein with coiled-coil

0.72	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination
0.69	GO:0044783	G1 DNA damage checkpoint
0.68	GO:0010390	histone monoubiquitination
0.60	GO:0045893	positive regulation of transcription, DNA-templated
0.58	GO:0009247	glycolipid biosynthetic process
0.48	GO:0006351	transcription, DNA-templated
0.46	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.45	GO:0016239	positive regulation of macroautophagy

0.69	GO:0000993	RNA polymerase II core binding
0.67	GO:0050694	galactose 3-O-sulfotransferase activity
0.63	GO:0003682	chromatin binding

0.57	GO:0005794	Golgi apparatus
0.54	GO:0005634	nucleus
0.46	GO:0043233	organelle lumen
0.42	GO:0044446	intracellular organelle part
0.39	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.67

GO:0050694

tr|Q7ZUK9|Q7ZUK9_DANRE
Regulation of nuclear pre-mRNA domain containing 1B
Search

RPRD1B

0.95	Regulation of nuclear pre-mRNA domain-containing protein 1B

0.85	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain
0.78	GO:0008284	positive regulation of cell proliferation
0.74	GO:0010564	regulation of cell cycle process
0.74	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:0042795	snRNA transcription by RNA polymerase II

0.84	GO:0000993	RNA polymerase II core binding
0.73	GO:0042802	identical protein binding
0.35	GO:0003723	RNA binding

0.77	GO:0005813	centrosome
0.75	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
0.68	GO:0005829	cytosol

tr|Q7ZUL1|Q7ZUL1_DANRE
Monocarboxylate transporter 1a
Search

SLC16A1

0.85	Solute carrier family 16 (Monocarboxylic acid transporters), member 1

0.80	GO:0035873	lactate transmembrane transport
0.55	GO:0051780	behavioral response to nutrient
0.54	GO:0032094	response to food
0.52	GO:0007098	centrosome cycle
0.52	GO:0050796	regulation of insulin secretion
0.50	GO:0042593	glucose homeostasis
0.46	GO:1901475	pyruvate transmembrane transport
0.43	GO:0006629	lipid metabolic process
0.37	GO:0071407	cellular response to organic cyclic compound

0.80	GO:0015129	lactate transmembrane transporter activity
0.41	GO:0050833	pyruvate transmembrane transporter activity
0.37	GO:0042803	protein homodimerization activity
0.32	GO:0097159	organic cyclic compound binding

0.67	GO:0005887	integral component of plasma membrane
0.50	GO:0005813	centrosome
0.48	GO:0030054	cell junction
0.42	GO:0005739	mitochondrion

tr|Q7ZUL7|Q7ZUL7_DANRE
RNA binding protein
Search

RBPMS2

0.92	RNA-binding protein with multiple splicing

0.54	GO:0051151	negative regulation of smooth muscle cell differentiation
0.44	GO:0060391	positive regulation of SMAD protein import into nucleus
0.44	GO:0000398	mRNA splicing, via spliceosome
0.43	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.40	GO:0090259	regulation of retinal ganglion cell axon guidance
0.39	GO:0048557	embryonic digestive tract morphogenesis
0.39	GO:0048661	positive regulation of smooth muscle cell proliferation
0.39	GO:0031290	retinal ganglion cell axon guidance
0.39	GO:0030514	negative regulation of BMP signaling pathway
0.39	GO:0048813	dendrite morphogenesis

0.63	GO:0042803	protein homodimerization activity
0.58	GO:0003723	RNA binding
0.41	GO:0003713	transcription coactivator activity
0.35	GO:0008073	ornithine decarboxylase inhibitor activity

0.45	GO:0005685	U1 snRNP
0.40	GO:0010494	cytoplasmic stress granule
0.38	GO:0005654	nucleoplasm
0.38	GO:0005829	cytosol
0.34	GO:0000932	P-body

tr|Q7ZUL8|Q7ZUL8_DANRE
Zgc:55558
Search

KRAS

0.85	KRAS proto-oncogene, GTPase

0.61	GO:0007165	signal transduction
0.53	GO:0008284	positive regulation of cell proliferation
0.49	GO:0001936	regulation of endothelial cell proliferation
0.47	GO:0038002	endocrine signaling
0.47	GO:0021897	forebrain astrocyte development
0.46	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.46	GO:0035022	positive regulation of Rac protein signal transduction
0.45	GO:0060441	epithelial tube branching involved in lung morphogenesis
0.45	GO:0043524	negative regulation of neuron apoptotic process
0.45	GO:0048873	homeostasis of number of cells within a tissue

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.49	GO:0032403	protein complex binding
0.36	GO:0003876	AMP deaminase activity
0.36	GO:0019003	GDP binding
0.36	GO:0008022	protein C-terminus binding
0.32	GO:0003677	DNA binding
0.32	GO:0046872	metal ion binding

0.46	GO:0005794	Golgi apparatus
0.44	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.39	GO:0098588	bounding membrane of organelle
0.38	GO:0031984	organelle subcompartment
0.36	GO:0070062	extracellular exosome
0.35	GO:0070820	tertiary granule
0.34	GO:0030659	cytoplasmic vesicle membrane
0.33	GO:0098805	whole membrane
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.36

EC:3.5.4.6

GO:0003876

sp|Q7ZUL9|MGRN1_DANRE
Probable E3 ubiquitin-protein ligase MGRN1
Search

0.90	Mahogunin ring finger 1

0.86	GO:0043951	negative regulation of cAMP-mediated signaling
0.85	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway
0.85	GO:0008333	endosome to lysosome transport
0.83	GO:0006513	protein monoubiquitination
0.79	GO:0000209	protein polyubiquitination

0.74	GO:0061630	ubiquitin protein ligase activity
0.37	GO:0016874	ligase activity

0.79	GO:0005769	early endosome
0.61	GO:0005634	nucleus

0.37

GO:0016874

tr|Q7ZUM0|Q7ZUM0_DANRE
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a
Search

YWHAZ

0.80	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta

0.51	GO:0090168	Golgi reassembly
0.50	GO:0051683	establishment of Golgi localization
0.45	GO:0010941	regulation of cell death
0.44	GO:0006605	protein targeting
0.39	GO:0055114	oxidation-reduction process
0.35	GO:0001775	cell activation
0.35	GO:0006839	mitochondrial transport
0.35	GO:0002441	histamine secretion involved in inflammatory response
0.35	GO:0007005	mitochondrion organization
0.35	GO:0002448	mast cell mediated immunity

0.77	GO:0019904	protein domain specific binding
0.48	GO:0044325	ion channel binding
0.47	GO:0045296	cadherin binding
0.46	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0019901	protein kinase binding
0.45	GO:0004497	monooxygenase activity
0.45	GO:0042802	identical protein binding
0.44	GO:0008134	transcription factor binding
0.34	GO:0003723	RNA binding
0.34	GO:0032403	protein complex binding

0.41	GO:0005634	nucleus
0.41	GO:0005739	mitochondrion
0.40	GO:0042470	melanosome
0.36	GO:0072562	blood microparticle
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0030659	cytoplasmic vesicle membrane
0.35	GO:0042629	mast cell granule
0.34	GO:0005829	cytosol
0.34	GO:0014069	postsynaptic density

sp|Q7ZUM8|UBP44_DANRE
Ubiquitin carboxyl-terminal hydrolase 44
Search

USP44

0.58	Ubiquitin carboxyl-terminal hydrolase 44-B

0.76	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.71	GO:1904667	negative regulation of ubiquitin protein ligase activity
0.56	GO:0051301	cell division
0.56	GO:0007049	cell cycle
0.52	GO:0021551	central nervous system morphogenesis
0.50	GO:1904888	cranial skeletal system development
0.49	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint
0.45	GO:0000398	mRNA splicing, via spliceosome
0.45	GO:0010498	proteasomal protein catabolic process

0.77	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.54	GO:0008270	zinc ion binding
0.47	GO:0042393	histone binding
0.45	GO:0004197	cysteine-type endopeptidase activity

0.53	GO:0005634	nucleus
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part

0.77

EC:3.4.19.12

GO:0036459

tr|Q7ZUN1|Q7ZUN1_DANRE
Slc25a32a protein
Search

SLC25A32

0.89	Mitochondrial folate transporter

0.57	GO:0006839	mitochondrial transport
0.49	GO:0015884	folic acid transport
0.49	GO:0035350	FAD transmembrane transport
0.47	GO:0006544	glycine metabolic process
0.36	GO:0035461	vitamin transmembrane transport
0.35	GO:0006855	drug transmembrane transport
0.35	GO:1903825	organic acid transmembrane transport
0.34	GO:0046655	folic acid metabolic process

0.49	GO:0008517	folic acid transmembrane transporter activity
0.49	GO:0015230	FAD transmembrane transporter activity

0.48	GO:0005739	mitochondrion
0.48	GO:0031967	organelle envelope
0.48	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q7ZUN2|Q7ZUN2_DANRE
NIMA (Never in mitosis gene a)-related kinase 2
Search

NEK2

0.95	Serine/threonine-protein kinase Nek2

0.63	GO:0006468	protein phosphorylation
0.61	GO:1903126	negative regulation of centriole-centriole cohesion
0.58	GO:0046602	regulation of mitotic centrosome separation
0.58	GO:1904355	positive regulation of telomere capping
0.57	GO:0051299	centrosome separation
0.57	GO:0051973	positive regulation of telomerase activity
0.57	GO:0032212	positive regulation of telomere maintenance via telomerase
0.57	GO:0051988	regulation of attachment of spindle microtubules to kinetochore
0.55	GO:0043392	negative regulation of DNA binding
0.54	GO:0090307	mitotic spindle assembly

0.64	GO:0004672	protein kinase activity
0.55	GO:0019903	protein phosphatase binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0001222	transcription corepressor binding
0.36	GO:0019894	kinesin binding
0.36	GO:0033613	activating transcription factor binding
0.35	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0019901	protein kinase binding

0.53	GO:0030496	midbody
0.53	GO:0005813	centrosome
0.53	GO:0000776	kinetochore
0.52	GO:0000922	spindle pole
0.52	GO:0000794	condensed nuclear chromosome
0.49	GO:0005654	nucleoplasm
0.36	GO:0000779	condensed chromosome, centromeric region
0.35	GO:0005730	nucleolus
0.35	GO:0005874	microtubule
0.35	GO:0005829	cytosol

0.34

EC:2.3.1.97

GO:0004379

tr|Q7ZUN7|Q7ZUN7_DANRE
Ckmt1 protein
Search

0.87	Mitochondrial creatine kinase s-type

0.56	GO:0016310	phosphorylation
0.38	GO:0032091	negative regulation of protein binding
0.37	GO:0043066	negative regulation of apoptotic process
0.37	GO:0006600	creatine metabolic process
0.37	GO:0007519	skeletal muscle tissue development
0.36	GO:0006599	phosphagen metabolic process
0.35	GO:0021549	cerebellum development
0.35	GO:0048565	digestive tract development
0.35	GO:0001822	kidney development
0.35	GO:0006936	muscle contraction

0.59	GO:0016301	kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor
0.35	GO:1901612	cardiolipin binding
0.34	GO:0042803	protein homodimerization activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.46	GO:0005739	mitochondrion
0.38	GO:0019866	organelle inner membrane
0.38	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome
0.35	GO:0043204	perikaryon
0.30	GO:0031224	intrinsic component of membrane

0.40

EC:2.7.3

GO:0016775

sp|Q7ZUN8|YKT6_DANRE
Synaptobrevin homolog YKT6
Search

YKT6

0.92	Synaptobrevin like protein YKT6

0.67	GO:0016192	vesicle-mediated transport
0.51	GO:0051650	establishment of vesicle localization
0.50	GO:0016482	cytosolic transport
0.50	GO:0140056	organelle localization by membrane tethering
0.49	GO:0016197	endosomal transport
0.48	GO:0032940	secretion by cell
0.47	GO:0061025	membrane fusion
0.46	GO:0048284	organelle fusion
0.46	GO:0016050	vesicle organization
0.38	GO:0015031	protein transport

0.53	GO:0005484	SNAP receptor activity
0.51	GO:0045296	cadherin binding
0.50	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.47	GO:0000149	SNARE binding
0.34	GO:0004683	calmodulin-dependent protein kinase activity
0.34	GO:0005516	calmodulin binding

0.48	GO:0005768	endosome
0.48	GO:0005794	Golgi apparatus
0.48	GO:0031201	SNARE complex
0.47	GO:0005829	cytosol
0.47	GO:0005783	endoplasmic reticulum
0.45	GO:0005887	integral component of plasma membrane
0.43	GO:0005739	mitochondrion
0.41	GO:0030659	cytoplasmic vesicle membrane
0.40	GO:0097441	basal dendrite
0.40	GO:0097440	apical dendrite

0.50

EC:2.3.1.225

GO:0019706

sp|Q7ZUP0|AN32A_DANRE
Acidic leucine-rich nuclear phosphoprotein 32 family member A
Search

ANP32A

0.92	Acidic leucine-rich nuclear phosphoprotein 32 family member A

0.71	GO:0006913	nucleocytoplasmic transport
0.69	GO:0043486	histone exchange
0.65	GO:0006334	nucleosome assembly
0.62	GO:0042981	regulation of apoptotic process
0.45	GO:0006351	transcription, DNA-templated
0.44	GO:0060255	regulation of macromolecule metabolic process
0.44	GO:0080090	regulation of primary metabolic process
0.44	GO:0031323	regulation of cellular metabolic process
0.44	GO:0051171	regulation of nitrogen compound metabolic process
0.44	GO:0009889	regulation of biosynthetic process

0.66	GO:0042393	histone binding
0.43	GO:0005178	integrin binding
0.42	GO:0008022	protein C-terminus binding
0.40	GO:0003723	RNA binding
0.36	GO:0070063	RNA polymerase binding

0.75	GO:0048471	perinuclear region of cytoplasm
0.67	GO:0005783	endoplasmic reticulum
0.61	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.39	GO:0005829	cytosol
0.34	GO:0043232	intracellular non-membrane-bounded organelle

sp|Q7ZUP1|FA46C_DANRE
Protein FAM46C
Search

FAM46C

0.97	Putative nucleotidyltransferase FAM46C

0.49	GO:1900046	regulation of hemostasis
0.49	GO:0050818	regulation of coagulation
0.49	GO:0061041	regulation of wound healing
0.46	GO:0032101	regulation of response to external stimulus
0.39	GO:0060255	regulation of macromolecule metabolic process

0.57	GO:0016779	nucleotidyltransferase activity
0.42	GO:0005515	protein binding
0.40	GO:0003723	RNA binding

0.57

GO:0016779

tr|Q7ZUP4|Q7ZUP4_DANRE
Eukaryotic translation initiation factor 5A
Search

EIF5A

0.65	Eukaryotic translation initiation factor 5A

0.83	GO:0045905	positive regulation of translational termination
0.83	GO:0045901	positive regulation of translational elongation
0.83	GO:0006452	translational frameshifting
0.59	GO:0006413	translational initiation
0.48	GO:0008284	positive regulation of cell proliferation
0.44	GO:0043065	positive regulation of apoptotic process
0.42	GO:0051028	mRNA transport
0.39	GO:0006611	protein export from nucleus
0.38	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.38	GO:0006915	apoptotic process

0.73	GO:0043022	ribosome binding
0.70	GO:0003746	translation elongation factor activity
0.60	GO:0003743	translation initiation factor activity
0.39	GO:0017070	U6 snRNA binding
0.39	GO:0047485	protein N-terminus binding
0.33	GO:0003735	structural constituent of ribosome

0.42	GO:0005643	nuclear pore
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.40	GO:0098827	endoplasmic reticulum subcompartment
0.38	GO:0098589	membrane region
0.35	GO:0043025	neuronal cell body
0.35	GO:0070062	extracellular exosome
0.35	GO:0030425	dendrite
0.34	GO:0005829	cytosol
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

tr|Q7ZUP7|Q7ZUP7_DANRE
Small nuclear RNA-activating complex, polypeptide 1b
Search

SNAPC1

0.97	Small nuclear RNA activating complex polypeptide 1

0.71	GO:0042796	snRNA transcription by RNA polymerase III
0.70	GO:0042795	snRNA transcription by RNA polymerase II
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:0010468	regulation of gene expression

0.53	GO:0043565	sequence-specific DNA binding
0.35	GO:0046983	protein dimerization activity
0.34	GO:0003700	DNA binding transcription factor activity

0.70	GO:0019185	snRNA-activating protein complex
0.69	GO:0005730	nucleolus
0.36	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|Q7ZUP9|Q7ZUP9_DANRE
Fizzy/cell division cycle 20 related 1 (Drosophila)
Search

FZR1

0.95	Fizzy and cell division cycle 20 related 1

0.83	GO:1904668	positive regulation of ubiquitin protein ligase activity
0.54	GO:0072425	signal transduction involved in G2 DNA damage checkpoint
0.54	GO:0070306	lens fiber cell differentiation
0.54	GO:0090344	negative regulation of cell aging
0.53	GO:0040020	regulation of meiotic nuclear division
0.52	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.51	GO:0045732	positive regulation of protein catabolic process
0.50	GO:0008284	positive regulation of cell proliferation
0.43	GO:0051301	cell division
0.36	GO:1904145	negative regulation of meiotic cell cycle process involved in oocyte maturation

0.84	GO:0097027	ubiquitin-protein transferase activator activity
0.84	GO:0010997	anaphase-promoting complex binding

0.51	GO:0005680	anaphase-promoting complex
0.51	GO:0031965	nuclear membrane
0.47	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol

tr|Q7ZUQ0|Q7ZUQ0_DANRE
Actin related protein 2/3 complex, subunit 1A
Search

ARPC1A

0.75	Actin-related protein 2/3 complex subunit

0.81	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.35	GO:0007018	microtubule-based movement
0.34	GO:0048013	ephrin receptor signaling pathway
0.33	GO:0061024	membrane organization

0.68	GO:0003779	actin binding
0.45	GO:0032403	protein complex binding
0.36	GO:0003774	motor activity
0.35	GO:0008017	microtubule binding
0.34	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0005885	Arp2/3 protein complex
0.55	GO:0036195	muscle cell projection membrane
0.46	GO:0005737	cytoplasm
0.36	GO:0016459	myosin complex
0.36	GO:0070062	extracellular exosome

tr|Q7ZUQ1|Q7ZUQ1_DANRE
Cdc42l protein
Search

CDC42

0.80	Cell division control protein 42

0.74	GO:0007264	small GTPase mediated signal transduction
0.59	GO:0051301	cell division
0.53	GO:0046847	filopodium assembly
0.52	GO:0038189	neuropilin signaling pathway
0.52	GO:0071338	positive regulation of hair follicle cell proliferation
0.52	GO:0051491	positive regulation of filopodium assembly
0.51	GO:0060684	epithelial-mesenchymal cell signaling
0.51	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis
0.51	GO:0060997	dendritic spine morphogenesis
0.51	GO:0048664	neuron fate determination

0.66	GO:0003924	GTPase activity
0.64	GO:0005525	GTP binding
0.52	GO:0051022	Rho GDP-dissociation inhibitor binding
0.51	GO:0032427	GBD domain binding
0.50	GO:0034191	apolipoprotein A-I receptor binding
0.50	GO:0030742	GTP-dependent protein binding
0.50	GO:0031996	thioesterase binding
0.46	GO:0019901	protein kinase binding
0.45	GO:0061630	ubiquitin protein ligase activity
0.44	GO:0042802	identical protein binding

0.49	GO:0031256	leading edge membrane
0.48	GO:0045335	phagocytic vesicle
0.48	GO:0051233	spindle midzone
0.48	GO:0043197	dendritic spine
0.48	GO:0043209	myelin sheath
0.48	GO:0030175	filopodium
0.48	GO:0030496	midbody
0.47	GO:0045177	apical part of cell
0.47	GO:0072686	mitotic spindle
0.47	GO:0000322	storage vacuole

0.34

GO:0004674

tr|Q7ZUQ2|Q7ZUQ2_DANRE
Ppp2r5e1 protein
Search

PPP2R5E

0.61	Serine/threonine protein phosphatase 2A regulatory subunit

0.79	GO:0043666	regulation of phosphoprotein phosphatase activity
0.61	GO:0007165	signal transduction
0.37	GO:0090219	negative regulation of lipid kinase activity
0.36	GO:1903077	negative regulation of protein localization to plasma membrane
0.36	GO:0035307	positive regulation of protein dephosphorylation
0.35	GO:0006470	protein dephosphorylation

0.80	GO:0019888	protein phosphatase regulator activity
0.35	GO:0005515	protein binding
0.35	GO:0004721	phosphoprotein phosphatase activity

0.81	GO:0000159	protein phosphatase type 2A complex
0.46	GO:0005829	cytosol
0.36	GO:0031430	M band
0.36	GO:0030018	Z disc
0.35	GO:0005813	centrosome
0.30	GO:0016020	membrane

0.35

GO:0004721

sp|Q7ZUQ3|STK3_DANRE
Serine/threonine-protein kinase 3
Search

STK3

0.92	Serine/threonine-protein kinase 3

0.62	GO:0060800	regulation of cell differentiation involved in embryonic placenta development
0.62	GO:0006468	protein phosphorylation
0.62	GO:0097284	hepatocyte apoptotic process
0.61	GO:0035329	hippo signaling
0.61	GO:0003157	endocardium development
0.61	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.60	GO:0060215	primitive hemopoiesis
0.60	GO:0046621	negative regulation of organ growth
0.59	GO:0045600	positive regulation of fat cell differentiation
0.59	GO:0032092	positive regulation of protein binding

0.67	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0042802	identical protein binding
0.48	GO:0000287	magnesium ion binding
0.45	GO:0008134	transcription factor binding
0.44	GO:0046983	protein dimerization activity
0.35	GO:0043539	protein serine/threonine kinase activator activity

0.47	GO:0016604	nuclear body
0.45	GO:0043234	protein complex
0.44	GO:0005829	cytosol

0.67

GO:0004674

tr|Q7ZUR5|Q7ZUR5_DANRE
Signal sequence receptor, gamma
Search

0.90	Translocon-associated protein subunit gamma

0.74

GO:0006614

SRP-dependent cotranslational protein targeting to membrane

0.45	GO:0005622	intracellular
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0044422	organelle part
0.36	GO:0043227	membrane-bounded organelle
0.34	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

tr|Q7ZUR6|Q7ZUR6_DANRE
Muscle-specific beta 1 integrin binding protein 2
Search

0.94	Muscle-specific beta 1 integrin-binding protein 2

0.52	GO:0016310	phosphorylation
0.51	GO:0007229	integrin-mediated signaling pathway
0.47	GO:0070831	basement membrane assembly
0.47	GO:0007045	cell-substrate adherens junction assembly
0.45	GO:0045662	negative regulation of myoblast differentiation
0.45	GO:0007517	muscle organ development
0.34	GO:0009435	NAD biosynthetic process

0.54	GO:0016301	kinase activity
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0046872	metal ion binding

0.40	GO:0005654	nucleoplasm
0.37	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0016773

sp|Q7ZUS1|VRK1_DANRE
Serine/threonine-protein kinase VRK1
Search

VRK1

0.88	Vaccinia related kinase 1

0.69	GO:0072355	histone H3-T3 phosphorylation
0.68	GO:0090166	Golgi disassembly
0.67	GO:0043987	histone H3-S10 phosphorylation
0.62	GO:0046777	protein autophosphorylation
0.44	GO:0008360	regulation of cell shape
0.37	GO:2000659	regulation of interleukin-1-mediated signaling pathway
0.36	GO:0043408	regulation of MAPK cascade
0.35	GO:0034599	cellular response to oxidative stress

0.69	GO:0072354	histone kinase activity (H3-T3 specific)
0.68	GO:0035175	histone kinase activity (H3-S10 specific)
0.66	GO:0031493	nucleosomal histone binding
0.60	GO:0019901	protein kinase binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0019904	protein domain specific binding

0.60	GO:0005795	Golgi stack
0.56	GO:0005730	nucleolus
0.54	GO:0005654	nucleoplasm
0.53	GO:0005829	cytosol
0.35	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q7ZUS4|ST2S2_DANRE
Cytosolic sulfotransferase 2
Search

0.58	Cytosolic sulfotransferase 2

0.39	GO:0006584	catecholamine metabolic process
0.39	GO:0006805	xenobiotic metabolic process
0.37	GO:0008202	steroid metabolic process
0.36	GO:0051923	sulfation
0.36	GO:0006068	ethanol catabolic process
0.36	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.35	GO:0034754	cellular hormone metabolic process

0.77

GO:0008146

sulfotransferase activity

0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.77

GO:0008146

tr|Q7ZUS6|Q7ZUS6_DANRE
DnaJ (Hsp40) homolog, subfamily C, member 4
Search

DNAJC4

0.97	DnaJ like protein subfamily C member 4

0.39	GO:0006457	protein folding
0.37	GO:0009408	response to heat
0.36	GO:0006986	response to unfolded protein

0.39	GO:0051082	unfolded protein binding
0.37	GO:0031072	heat shock protein binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046872	metal ion binding

0.45	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

tr|Q7ZUS7|Q7ZUS7_DANRE
Serine/threonine-protein phosphatase
Search

PPP6C

0.51	Serine/threonine-protein phosphatase 6 catalytic subunit

0.70	GO:0006470	protein dephosphorylation
0.44	GO:0001878	response to yeast
0.37	GO:0045087	innate immune response
0.35	GO:0007049	cell cycle
0.35	GO:0048208	COPII vesicle coating

0.71	GO:0004721	phosphoprotein phosphatase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.45	GO:0005829	cytosol
0.34	GO:0000139	Golgi membrane
0.33	GO:0005739	mitochondrion

0.71

GO:0004721

tr|Q7ZUT5|Q7ZUT5_DANRE
CAMP-regulated phosphoprotein 19b
Search

ARPP19

0.95	LOW QUALITY PROTEIN: cAMP-regulated phosphoprotein 19

0.82	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.66	GO:0051301	cell division
0.66	GO:0007049	cell cycle
0.47	GO:0050796	regulation of insulin secretion
0.38	GO:0045722	positive regulation of gluconeogenesis
0.37	GO:0009749	response to glucose
0.36	GO:0046579	positive regulation of Ras protein signal transduction
0.36	GO:0007212	dopamine receptor signaling pathway
0.34	GO:0007584	response to nutrient

0.83	GO:0004864	protein phosphatase inhibitor activity
0.49	GO:0015459	potassium channel regulator activity
0.47	GO:0008200	ion channel inhibitor activity
0.44	GO:0005102	receptor binding
0.43	GO:0051721	protein phosphatase 2A binding

0.49	GO:0005737	cytoplasm
0.33	GO:0005654	nucleoplasm

sp|Q7ZUU1|UNC50_DANRE
Protein unc-50 homolog
Search

UNC50

0.96	Unc-50 homolog (C. elegans)

0.44	GO:0015031	protein transport
0.41	GO:0007166	cell surface receptor signaling pathway

0.42

GO:0003723

RNA binding

0.52	GO:0005637	nuclear inner membrane
0.52	GO:0005794	Golgi apparatus
0.50	GO:0098588	bounding membrane of organelle
0.50	GO:0031301	integral component of organelle membrane
0.48	GO:0031984	organelle subcompartment

tr|Q7ZUU6|Q7ZUU6_DANRE
Creatine kinase, mitochondrial 2a (sarcomeric)
Search

0.67	Creatine kinase, mitochondrial 2

0.55	GO:0016310	phosphorylation
0.40	GO:0032091	negative regulation of protein binding
0.39	GO:0043066	negative regulation of apoptotic process
0.37	GO:0006600	creatine metabolic process
0.36	GO:0007519	skeletal muscle tissue development
0.36	GO:0006599	phosphagen metabolic process
0.35	GO:0021549	cerebellum development
0.35	GO:0048565	digestive tract development
0.35	GO:0006936	muscle contraction
0.35	GO:0001822	kidney development

0.58	GO:0016301	kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor
0.35	GO:1901612	cardiolipin binding
0.34	GO:0042803	protein homodimerization activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.45	GO:0005739	mitochondrion
0.40	GO:0043209	myelin sheath
0.38	GO:0019866	organelle inner membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0043204	perikaryon
0.30	GO:0044425	membrane part

0.40

EC:2.7.3

GO:0016775

sp|Q7ZUV0|AN13C_DANRE
Ankyrin repeat domain-containing protein 13C
Search

ANKRD13C

0.89	Ankyrin repeat domain-containing protein 13C-A

0.85	GO:0010869	regulation of receptor biosynthetic process
0.83	GO:0006621	protein retention in ER lumen
0.79	GO:2000209	regulation of anoikis

0.71

GO:0005102

receptor binding

0.71	GO:0048471	perinuclear region of cytoplasm
0.70	GO:0005783	endoplasmic reticulum
0.49	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.48	GO:0031984	organelle subcompartment
0.30	GO:0044425	membrane part

sp|Q7ZUV1|PKHF2_DANRE
Pleckstrin homology domain-containing family F member 2
Search

PLEKHF2

0.97	Pleckstrin homology and FYVE domain-containing 2

0.36	GO:0015031	protein transport
0.30	GO:0008152	metabolic process

0.54	GO:0046872	metal ion binding
0.34	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.33	GO:0005515	protein binding

0.50	GO:0030133	transport vesicle
0.39	GO:0031901	early endosome membrane
0.36	GO:0005783	endoplasmic reticulum

0.34	EC:3.2.1.113	GO:0004571
0.34	KEGG:R05982 KEGG:R06722	GO:0004571

sp|Q7ZUV2|KTNB1_DANRE
Katanin p80 WD40 repeat-containing subunit B1
Search

KATNB1

0.78	Katanin p80 (WD repeat containing) subunit B 1 (Fragment)

0.84	GO:0051013	microtubule severing
0.63	GO:0051301	cell division
0.63	GO:0007049	cell cycle
0.52	GO:0030901	midbrain development
0.51	GO:0031117	positive regulation of microtubule depolymerization
0.46	GO:0051303	establishment of chromosome localization
0.44	GO:0007026	negative regulation of microtubule depolymerization
0.44	GO:0000280	nuclear division
0.43	GO:0007018	microtubule-based movement
0.43	GO:0007059	chromosome segregation

0.74	GO:0008017	microtubule binding
0.44	GO:0070840	dynein complex binding
0.44	GO:0008568	microtubule-severing ATPase activity
0.41	GO:0046982	protein heterodimerization activity

0.85	GO:0008352	katanin complex
0.74	GO:0000922	spindle pole
0.73	GO:0005813	centrosome
0.69	GO:0005874	microtubule
0.43	GO:0030424	axon
0.40	GO:0005829	cytosol
0.37	GO:0005886	plasma membrane

0.44

EC:3.6.4.3

GO:0008568

tr|Q7ZUV5|Q7ZUV5_DANRE
ZRAB1B, member RAS oncogene family a
Search

0.85	ras-related protein ORAB-1

0.57	GO:1903020	positive regulation of glycoprotein metabolic process
0.54	GO:0006888	ER to Golgi vesicle-mediated transport
0.51	GO:0072606	interleukin-8 secretion
0.51	GO:0030252	growth hormone secretion
0.50	GO:0032402	melanosome transport
0.49	GO:0034446	substrate adhesion-dependent cell spreading
0.49	GO:0035459	cargo loading into vesicle
0.49	GO:0047496	vesicle transport along microtubule
0.49	GO:0019068	virion assembly
0.48	GO:2000785	regulation of autophagosome assembly

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0045296	cadherin binding
0.35	GO:0003777	microtubule motor activity
0.34	GO:0004713	protein tyrosine kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding

0.52	GO:0005794	Golgi apparatus
0.50	GO:0042470	melanosome
0.49	GO:0034045	phagophore assembly site membrane
0.48	GO:0098588	bounding membrane of organelle
0.47	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.47	GO:0031984	organelle subcompartment
0.45	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.45	GO:0044432	endoplasmic reticulum part
0.40	GO:0005739	mitochondrion
0.38	GO:0005769	early endosome

0.34

GO:0004713

sp|Q7ZUV7|EMSY_DANRE
BRCA2-interacting transcriptional repressor EMSY
Search

EMSY

0.93	BRCA2-interacting transcriptional repressor EMSY

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.40	GO:0016569	covalent chromatin modification
0.38	GO:0006281	DNA repair
0.37	GO:0006351	transcription, DNA-templated

0.40

GO:0042803

protein homodimerization activity

0.40

GO:0005654

nucleoplasm

tr|Q7ZUW0|Q7ZUW0_DANRE
DnaJ (Hsp40) homolog, subfamily A, member 3A
Search

DNAJA3

0.82	DnaJ like protein subfamily A member 3, mitochondrial

0.72	GO:0009408	response to heat
0.68	GO:0006457	protein folding
0.55	GO:0006924	activation-induced cell death of T cells
0.53	GO:0006264	mitochondrial DNA replication
0.52	GO:0033077	T cell differentiation in thymus
0.52	GO:0042102	positive regulation of T cell proliferation
0.52	GO:0007528	neuromuscular junction development
0.51	GO:0007569	cell aging
0.50	GO:0008285	negative regulation of cell proliferation
0.49	GO:0000122	negative regulation of transcription by RNA polymerase II

0.78	GO:0031072	heat shock protein binding
0.71	GO:0051082	unfolded protein binding
0.54	GO:0046872	metal ion binding
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0032555	purine ribonucleotide binding
0.48	GO:0030695	GTPase regulator activity
0.41	GO:0005133	interferon-gamma receptor binding
0.41	GO:0051059	NF-kappaB binding

0.52	GO:0031594	neuromuscular junction
0.51	GO:0042645	mitochondrial nucleoid
0.51	GO:0005884	actin filament
0.49	GO:0045211	postsynaptic membrane
0.48	GO:0019897	extrinsic component of plasma membrane
0.45	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.41	GO:0033256	I-kappaB/NF-kappaB complex
0.39	GO:1902554	serine/threonine protein kinase complex
0.35	GO:0030054	cell junction

sp|Q7ZUW2|HYOU1_DANRE
Hypoxia up-regulated protein 1
Search

HYOU1

0.93	Hypoxia up-regulated protein 1

0.61	GO:1903382	negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway
0.60	GO:1903297	regulation of hypoxia-induced intrinsic apoptotic signaling pathway
0.59	GO:1900038	negative regulation of cellular response to hypoxia
0.58	GO:0002931	response to ischemia
0.57	GO:0071456	cellular response to hypoxia
0.54	GO:0034976	response to endoplasmic reticulum stress
0.53	GO:0006888	ER to Golgi vesicle-mediated transport
0.35	GO:0034620	cellular response to unfolded protein
0.34	GO:0006898	receptor-mediated endocytosis
0.33	GO:0007165	signal transduction

0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0051087	chaperone binding

0.59	GO:0034663	endoplasmic reticulum chaperone complex
0.43	GO:0005788	endoplasmic reticulum lumen
0.37	GO:0005790	smooth endoplasmic reticulum
0.37	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.36	GO:0071682	endocytic vesicle lumen
0.30	GO:0031224	intrinsic component of membrane

tr|Q7ZUW5|Q7ZUW5_DANRE
RAB5A, member RAS oncogene family
Search

RAB5A

0.89	Member RAS oncogene family

0.54	GO:0051489	regulation of filopodium assembly
0.52	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway
0.51	GO:0051036	regulation of endosome size
0.51	GO:0060627	regulation of vesicle-mediated transport
0.51	GO:0045056	transcytosis
0.50	GO:0045022	early endosome to late endosome transport
0.50	GO:0098693	regulation of synaptic vesicle cycle
0.50	GO:0046928	regulation of neurotransmitter secretion
0.50	GO:0036465	synaptic vesicle recycling
0.48	GO:1903532	positive regulation of secretion by cell

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.50	GO:0019003	GDP binding
0.35	GO:0051021	GDP-dissociation inhibitor binding
0.33	GO:0004402	histone acetyltransferase activity
0.32	GO:0046872	metal ion binding

0.54	GO:0005769	early endosome
0.53	GO:0030139	endocytic vesicle
0.51	GO:0001726	ruffle
0.51	GO:0010009	cytoplasmic side of endosome membrane
0.50	GO:0098857	membrane microdomain
0.50	GO:0043195	terminal bouton
0.47	GO:0036477	somatodendritic compartment
0.47	GO:0015629	actin cytoskeleton
0.44	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane

0.33

GO:0004402

sp|Q7ZUW6|WIPI3_DANRE
WD repeat domain phosphoinositide-interacting protein 3
Search

WDR45B

0.91	WD repeat domain phosphoinositide-interacting protein 3

0.83	GO:0034497	protein localization to phagophore assembly site
0.82	GO:0044804	autophagy of nucleus
0.81	GO:0000422	autophagy of mitochondrion
0.74	GO:0006497	protein lipidation

0.82	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.79	GO:0032266	phosphatidylinositol-3-phosphate binding
0.44	GO:0003924	GTPase activity
0.43	GO:0032550	purine ribonucleoside binding
0.43	GO:0019001	guanyl nucleotide binding
0.39	GO:0032555	purine ribonucleotide binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0034045	phagophore assembly site membrane
0.72	GO:0019898	extrinsic component of membrane
0.66	GO:0005829	cytosol

sp|Q7ZUW7|MDM4_DANRE
Protein Mdm4
Search

tr|Q7ZUW8|Q7ZUW8_DANRE
Aspartate aminotransferase
Search

GOT1

0.50	Aspartate aminotransferase

0.60	GO:0006532	aspartate biosynthetic process
0.60	GO:0006114	glycerol biosynthetic process
0.60	GO:0019550	glutamate catabolic process to aspartate
0.59	GO:0006533	aspartate catabolic process
0.58	GO:0055089	fatty acid homeostasis
0.56	GO:0051384	response to glucocorticoid
0.55	GO:0032869	cellular response to insulin stimulus
0.55	GO:0006103	2-oxoglutarate metabolic process
0.54	GO:0007219	Notch signaling pathway
0.54	GO:0006107	oxaloacetate metabolic process

0.81	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity
0.78	GO:0070546	L-phenylalanine aminotransferase activity
0.66	GO:0030170	pyridoxal phosphate binding
0.53	GO:0004609	phosphatidylserine decarboxylase activity
0.47	GO:0047801	L-cysteine:2-oxoglutarate aminotransferase activity
0.37	GO:0031406	carboxylic acid binding

0.49	GO:0005829	cytosol
0.49	GO:0005654	nucleoplasm
0.39	GO:0005739	mitochondrion
0.39	GO:0043679	axon terminus
0.38	GO:0005764	lysosome
0.36	GO:0070062	extracellular exosome

0.81	EC:2.6.1.1	GO:0004069
0.81	KEGG:R00355	GO:0004069

sp|Q7ZUX1|RPC3_DANRE
DNA-directed RNA polymerase III subunit RPC3
Search

POLR3C

0.88	RNA polymerase III subunit C

0.59	GO:0032728	positive regulation of interferon-beta production
0.58	GO:0006351	transcription, DNA-templated
0.56	GO:0045089	positive regulation of innate immune response
0.39	GO:0045087	innate immune response
0.39	GO:0051607	defense response to virus
0.35	GO:0006359	regulation of transcription by RNA polymerase III

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.54	GO:0003677	DNA binding
0.34	GO:0005515	protein binding

0.57	GO:0005666	DNA-directed RNA polymerase III complex
0.34	GO:0005829	cytosol

0.70

GO:0003899

sp|Q7ZUX3|WIPI4_DANRE
WD repeat domain phosphoinositide-interacting protein 4
Search

WDR45

0.94	WD repeat domain phosphoinositide-interacting protein 4

0.77	GO:0006914	autophagy
0.47	GO:0061726	mitochondrion disassembly
0.46	GO:0007033	vacuole organization
0.45	GO:0006497	protein lipidation
0.43	GO:0070925	organelle assembly
0.42	GO:0034613	cellular protein localization

0.47	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.47	GO:0032266	phosphatidylinositol-3-phosphate binding
0.34	GO:0046983	protein dimerization activity

0.47	GO:0034045	phagophore assembly site membrane
0.44	GO:0019898	extrinsic component of membrane
0.42	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|Q7ZUX5|Q7ZUX5_DANRE
RNA 3'-terminal phosphate cyclase
Search

RTCA

0.62	RNA terminal phosphate cyclase domain 1

0.61

GO:0006396

RNA processing

0.83	GO:0003963	RNA-3'-phosphate cyclase activity
0.52	GO:0030554	adenyl nucleotide binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003723	RNA binding

0.48	GO:0005654	nucleoplasm
0.30	GO:0044425	membrane part

0.83

EC:6.5.1.4

GO:0003963

sp|Q7ZUX6|DOHH_DANRE
Deoxyhypusine hydroxylase
Search

DOHH

0.74	Deoxyhypusine hydroxylase

0.79	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine
0.51	GO:0055114	oxidation-reduction process
0.34	GO:0006915	apoptotic process

0.84	GO:0019135	deoxyhypusine monooxygenase activity
0.51	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.34	GO:0005761	mitochondrial ribosome
0.33	GO:0005829	cytosol
0.33	GO:0015935	small ribosomal subunit
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:1.14.99.29

GO:0019135

tr|Q7ZUX8|Q7ZUX8_DANRE
Dynein, light chain, roadblock-type 1
Search

DYNLRB1

0.82	Dynein light chain roadblock

0.72	GO:0007018	microtubule-based movement
0.38	GO:0007632	visual behavior
0.35	GO:0030705	cytoskeleton-dependent intracellular transport
0.35	GO:0007179	transforming growth factor beta receptor signaling pathway
0.34	GO:0031503	protein complex localization
0.34	GO:0060271	cilium assembly
0.33	GO:0006914	autophagy
0.33	GO:0006886	intracellular protein transport

0.79	GO:0045505	dynein intermediate chain binding
0.67	GO:0003774	motor activity
0.35	GO:0042802	identical protein binding

0.80	GO:0005868	cytoplasmic dynein complex
0.67	GO:0005874	microtubule
0.50	GO:0036157	outer dynein arm
0.47	GO:0005813	centrosome
0.35	GO:0097542	ciliary tip
0.34	GO:1904115	axon cytoplasm
0.33	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005819	spindle
0.33	GO:0005938	cell cortex
0.33	GO:0005694	chromosome

tr|Q7ZUY0|Q7ZUY0_DANRE
SET translocation (Myeloid leukemia-associated) A
Search

SET

0.97	SET nuclear proto-oncogene a

0.79	GO:0006334	nucleosome assembly
0.43	GO:0048884	neuromast development
0.38	GO:0043524	negative regulation of neuron apoptotic process
0.36	GO:0045892	negative regulation of transcription, DNA-templated
0.35	GO:0006468	protein phosphorylation
0.35	GO:0007165	signal transduction
0.34	GO:0035067	negative regulation of histone acetylation
0.34	GO:0031498	chromatin disassembly
0.34	GO:0032986	protein-DNA complex disassembly
0.34	GO:0043488	regulation of mRNA stability

0.38	GO:0017049	GTP-Rho binding
0.36	GO:0004674	protein serine/threonine kinase activity
0.34	GO:0004864	protein phosphatase inhibitor activity
0.34	GO:0042393	histone binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.38	GO:0005811	lipid droplet
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0005829	cytosol
0.35	GO:0044446	intracellular organelle part
0.35	GO:0043234	protein complex

0.36

GO:0004674

sp|Q7ZUY3|H2AX_DANRE
Histone H2AX
Search

sp|Q7ZUZ0|CSN8_DANRE
COP9 signalosome complex subunit 8
Search

COPS8

0.93	COP9 constitutive photomorphogenic homolog subunit 8

0.86	GO:0010387	COP9 signalosome assembly
0.83	GO:0000338	protein deneddylation
0.54	GO:0007250	activation of NF-kappaB-inducing kinase activity
0.50	GO:0008285	negative regulation of cell proliferation
0.34	GO:0043687	post-translational protein modification
0.34	GO:0000715	nucleotide-excision repair, DNA damage recognition
0.34	GO:0006283	transcription-coupled nucleotide-excision repair
0.34	GO:0006413	translational initiation

0.34	GO:0003743	translation initiation factor activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding
0.33	GO:0016874	ligase activity

0.80	GO:0008180	COP9 signalosome
0.50	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.33

GO:0016874

tr|Q7ZUZ2|Q7ZUZ2_DANRE
ARP1 actin-related protein 1, centractin (yeast)
Search

0.94	Alpha-centractin

0.37	GO:0007283	spermatogenesis
0.37	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.34	GO:0006888	ER to Golgi vesicle-mediated transport

0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.82	GO:0005869	dynactin complex
0.57	GO:0005813	centrosome
0.52	GO:0099738	cell cortex region
0.51	GO:0043209	myelin sheath
0.38	GO:0002177	manchette
0.38	GO:0070062	extracellular exosome
0.37	GO:0005814	centriole
0.37	GO:0030137	COPI-coated vesicle
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen

tr|Q7ZUZ4|Q7ZUZ4_DANRE
Programmed cell death 5
Search

PDCD5

0.94	Programmed Cell death protein 5

0.55	GO:1903645	negative regulation of chaperone-mediated protein folding
0.55	GO:1903638	positive regulation of protein import into mitochondrial outer membrane
0.52	GO:0090200	positive regulation of release of cytochrome c from mitochondria
0.51	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.50	GO:0071560	cellular response to transforming growth factor beta stimulus
0.49	GO:0008285	negative regulation of cell proliferation
0.46	GO:0010628	positive regulation of gene expression
0.46	GO:0012501	programmed cell death
0.32	GO:0019538	protein metabolic process
0.32	GO:0043043	peptide biosynthetic process

0.55	GO:0003677	DNA binding
0.53	GO:0010698	acetyltransferase activator activity
0.51	GO:0048487	beta-tubulin binding
0.50	GO:0008201	heparin binding
0.33	GO:0004180	carboxypeptidase activity
0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0003735	structural constituent of ribosome
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005634	nucleus
0.42	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.32	GO:0015935	small ribosomal subunit
0.30	GO:0031224	intrinsic component of membrane

tr|Q7ZUZ7|Q7ZUZ7_DANRE
ADP-ribosylation factor 1
Search

ARF1

0.77	ADP-ribosylation factor 1 like

0.53	GO:1990386	mitotic cleavage furrow ingression
0.49	GO:0016192	vesicle-mediated transport
0.49	GO:0098586	cellular response to virus
0.48	GO:0006878	cellular copper ion homeostasis
0.42	GO:0060292	long term synaptic depression
0.41	GO:0097061	dendritic spine organization
0.41	GO:0002090	regulation of receptor internalization
0.41	GO:1903337	positive regulation of vacuolar transport
0.41	GO:0015031	protein transport
0.41	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation

0.64	GO:0005525	GTP binding
0.46	GO:0019904	protein domain specific binding
0.45	GO:0046982	protein heterodimerization activity
0.42	GO:0000287	magnesium ion binding
0.41	GO:1990583	phospholipase D activator activity
0.39	GO:0019003	GDP binding
0.34	GO:0003924	GTPase activity
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.34	GO:0003723	RNA binding

0.51	GO:0005794	Golgi apparatus
0.48	GO:0030017	sarcomere
0.48	GO:0031252	cell leading edge
0.44	GO:0005829	cytosol
0.42	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0043234	protein complex
0.40	GO:0014069	postsynaptic density
0.39	GO:0031982	vesicle
0.39	GO:0043230	extracellular organelle
0.39	GO:0045211	postsynaptic membrane

sp|Q7ZV00|OTU6B_DANRE
OTU domain-containing protein 6B
Search

OTUD6B

0.90	OTU domain-containing protein 2

0.65	GO:1990167	protein K27-linked deubiquitination
0.65	GO:1990168	protein K33-linked deubiquitination
0.65	GO:0035523	protein K29-linked deubiquitination
0.63	GO:0035871	protein K11-linked deubiquitination
0.49	GO:0008283	cell proliferation
0.43	GO:0042089	cytokine biosynthetic process

0.69

GO:0036459

thiol-dependent ubiquitinyl hydrolase activity

0.51

GO:0005829

cytosol

0.69

EC:3.4.19.12

GO:0036459

sp|Q7ZV03|VP26B_DANRE
Vacuolar protein sorting-associated protein 26B
Search

VPS26B

0.94	Vacuolar protein sorting-associated protein 26B-B

0.61	GO:0007165	signal transduction
0.54	GO:0042147	retrograde transport, endosome to Golgi
0.54	GO:0071346	cellular response to interferon-gamma
0.44	GO:0006886	intracellular protein transport
0.39	GO:0030111	regulation of Wnt signaling pathway
0.34	GO:0016241	regulation of macroautophagy
0.34	GO:0030510	regulation of BMP signaling pathway
0.34	GO:0198738	cell-cell signaling by wnt

0.43	GO:0008565	protein transporter activity
0.33	GO:0005515	protein binding

0.56	GO:0030904	retromer complex
0.53	GO:0045335	phagocytic vesicle
0.53	GO:0005768	endosome
0.48	GO:0005829	cytosol
0.34	GO:0044433	cytoplasmic vesicle part
0.34	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle

tr|Q7ZV05|Q7ZV05_DANRE
Ribosomal protein S11
Search

RPS11

0.61	Ribosomal protein S11

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0010469	regulation of receptor activity
0.35	GO:0001649	osteoblast differentiation
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.37	GO:0019843	rRNA binding
0.36	GO:0005125	cytokine activity
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.61	GO:0005840	ribosome
0.51	GO:0044445	cytosolic part
0.44	GO:0044446	intracellular organelle part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016620

tr|Q7ZV08|Q7ZV08_DANRE
Secretory carrier-associated membrane protein
Search

SCAMP2

0.67	Secretory carrier-associated membrane protein 2

0.65	GO:0015031	protein transport
0.35	GO:0006892	post-Golgi vesicle-mediated transport
0.35	GO:0006468	protein phosphorylation
0.33	GO:0006897	endocytosis
0.33	GO:0046907	intracellular transport
0.33	GO:0034613	cellular protein localization

0.43	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008565	protein transporter activity

0.53	GO:0032588	trans-Golgi network membrane
0.53	GO:0055038	recycling endosome membrane
0.38	GO:0030133	transport vesicle
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

tr|Q7ZV11|Q7ZV11_DANRE
Polymerase (RNA) II (DNA directed) polypeptide C
Search

POLR2C

0.86	RNA polymerase II subunit C

0.56	GO:0006351	transcription, DNA-templated
0.37	GO:0006744	ubiquinone biosynthetic process
0.35	GO:0035019	somatic stem cell population maintenance
0.35	GO:0060964	regulation of gene silencing by miRNA
0.35	GO:0008543	fibroblast growth factor receptor signaling pathway
0.35	GO:0016073	snRNA metabolic process
0.34	GO:0050434	positive regulation of viral transcription
0.34	GO:0006283	transcription-coupled nucleotide-excision repair
0.34	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0006370	7-methylguanosine mRNA capping

0.68	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.66	GO:0046983	protein dimerization activity
0.48	GO:0003677	DNA binding

0.53	GO:0005665	DNA-directed RNA polymerase II, core complex
0.48	GO:0015630	microtubule cytoskeleton
0.47	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0003899

tr|Q7ZV13|Q7ZV13_DANRE
Serine/arginine-rich-splicing factor 2a
Search

SRSF2

0.92	Serine and arginine rich splicing factor 2

0.76	GO:0043484	regulation of RNA splicing
0.45	GO:0050684	regulation of mRNA processing
0.41	GO:0033197	response to vitamin E
0.40	GO:0008380	RNA splicing
0.39	GO:0006397	mRNA processing
0.37	GO:0000278	mitotic cell cycle
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0031123	RNA 3'-end processing
0.34	GO:0051028	mRNA transport

0.59	GO:0003723	RNA binding
0.39	GO:0005080	protein kinase C binding
0.34	GO:0003714	transcription corepressor activity
0.33	GO:0004623	phospholipase A2 activity

0.49	GO:0016607	nuclear speck
0.45	GO:0005681	spliceosomal complex
0.44	GO:0005829	cytosol
0.40	GO:0035061	interchromatin granule
0.37	GO:0016605	PML body
0.36	GO:0070062	extracellular exosome
0.33	GO:0000785	chromatin
0.33	GO:0019013	viral nucleocapsid
0.30	GO:0016020	membrane

0.33

EC:3.1.1.4

GO:0004623

sp|Q7ZV14|GPX8_DANRE
Probable glutathione peroxidase 8
Search

GPX8

0.48	Glutathione peroxidase

0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.53	GO:0055114	oxidation-reduction process
0.33	GO:0033554	cellular response to stress

0.79	GO:0004602	glutathione peroxidase activity
0.39	GO:0004096	catalase activity

0.38	GO:0005783	endoplasmic reticulum
0.33	GO:0043233	organelle lumen
0.33	GO:0005576	extracellular region
0.33	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

0.79

EC:1.11.1.9

GO:0004602

sp|Q7ZV15|S22BA_DANRE
Vesicle-trafficking protein SEC22b-A
Search

SEC22B

0.96	SEC22 homolog B, vesicle trafficking protein b

0.67	GO:0016192	vesicle-mediated transport
0.55	GO:1902902	negative regulation of autophagosome assembly
0.51	GO:0045732	positive regulation of protein catabolic process
0.47	GO:0090174	organelle membrane fusion
0.46	GO:0016050	vesicle organization
0.43	GO:0032940	secretion by cell
0.43	GO:0046907	intracellular transport
0.38	GO:0015031	protein transport
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.34	GO:0051650	establishment of vesicle localization

0.47	GO:0000149	SNARE binding
0.47	GO:0005484	SNAP receptor activity

0.54	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.51	GO:0012507	ER to Golgi transport vesicle membrane
0.48	GO:0005789	endoplasmic reticulum membrane
0.48	GO:0005794	Golgi apparatus
0.48	GO:0031201	SNARE complex
0.43	GO:0042470	melanosome
0.35	GO:0030670	phagocytic vesicle membrane
0.34	GO:0070382	exocytic vesicle
0.30	GO:0016021	integral component of membrane

tr|Q7ZV18|Q7ZV18_DANRE
Placental syntaxin 4A
Search

STX2

0.95	Epimorphin

0.75	GO:0007340	acrosome reaction
0.69	GO:0016192	vesicle-mediated transport
0.67	GO:0006886	intracellular protein transport
0.67	GO:0061025	membrane fusion
0.63	GO:0030154	cell differentiation
0.51	GO:1903575	cornified envelope assembly
0.51	GO:0033194	response to hydroperoxide
0.47	GO:0097480	establishment of synaptic vesicle localization
0.47	GO:0099504	synaptic vesicle cycle
0.47	GO:0099643	signal release from synapse

0.79	GO:0005484	SNAP receptor activity
0.46	GO:0000149	SNARE binding
0.43	GO:0046983	protein dimerization activity
0.37	GO:0048306	calcium-dependent protein binding
0.35	GO:0016230	sphingomyelin phosphodiesterase activator activity

0.48	GO:0030027	lamellipodium
0.48	GO:0016323	basolateral plasma membrane
0.46	GO:0031201	SNARE complex
0.46	GO:0098793	presynapse
0.45	GO:0070382	exocytic vesicle
0.45	GO:0005615	extracellular space
0.36	GO:0009986	cell surface
0.35	GO:1903561	extracellular vesicle
0.35	GO:0045121	membrane raft
0.35	GO:0005911	cell-cell junction

sp|Q7ZV20|RRP15_DANRE
RRP15-like protein
Search

RRP15

0.97	Ribosomal RNA processing 15 homolog

0.69	GO:0006364	rRNA processing
0.46	GO:0042273	ribosomal large subunit biogenesis

0.47

GO:0030687

preribosome, large subunit precursor

sp|Q7ZV22|MTAP_DANRE
S-methyl-5'-thioadenosine phosphorylase
Search

MTAP

0.66	S-methyl-5'-thioadenosine phosphorylase

0.71	GO:0006166	purine ribonucleoside salvage
0.70	GO:0019509	L-methionine salvage from methylthioadenosine
0.40	GO:0032259	methylation
0.38	GO:0070638	pyridine nucleoside catabolic process
0.37	GO:0046495	nicotinamide riboside metabolic process
0.35	GO:0035722	interleukin-12-mediated signaling pathway
0.35	GO:0033574	response to testosterone

0.81	GO:0017061	S-methyl-5-thioadenosine phosphorylase activity
0.34	GO:0004645	phosphorylase activity
0.33	GO:0005515	protein binding

0.57	GO:0005634	nucleus
0.46	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.81

EC:2.4.2.28

GO:0017061

tr|Q7ZV23|Q7ZV23_DANRE
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
Search

SNU13

0.96	Small nuclear ribonucleoprotein 13

0.67	GO:0042254	ribosome biogenesis
0.50	GO:0000492	box C/D snoRNP assembly
0.48	GO:0007338	single fertilization
0.44	GO:0008380	RNA splicing
0.43	GO:0006397	mRNA processing
0.42	GO:0016072	rRNA metabolic process
0.41	GO:0034470	ncRNA processing
0.40	GO:0043043	peptide biosynthetic process
0.38	GO:0044267	cellular protein metabolic process
0.37	GO:0009059	macromolecule biosynthetic process

0.59	GO:0003723	RNA binding
0.50	GO:0051117	ATPase binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0016787	hydrolase activity

0.73	GO:0005730	nucleolus
0.61	GO:0030529	intracellular ribonucleoprotein complex
0.45	GO:0120114	Sm-like protein family complex
0.43	GO:0044445	cytosolic part
0.40	GO:0043234	protein complex
0.33	GO:0005654	nucleoplasm
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016787

tr|Q7ZV25|Q7ZV25_DANRE
Tubulin-specific chaperone A
Search

TBCA

0.73	Tubulin-specific chaperone A

0.84	GO:0007021	tubulin complex assembly
0.84	GO:0007023	post-chaperonin tubulin folding pathway
0.37	GO:0007420	brain development

0.84	GO:0048487	beta-tubulin binding
0.34	GO:0051087	chaperone binding
0.33	GO:0003723	RNA binding
0.32	GO:0016740	transferase activity

0.73	GO:0005874	microtubule
0.49	GO:0005737	cytoplasm
0.45	GO:0005730	nucleolus
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016740

sp|Q7ZV26|SOSSC_DANRE
SOSS complex subunit C
Search

INIP

0.96	INTS3 and NABP interacting protein (Fragment)

0.67	GO:0010212	response to ionizing radiation
0.65	GO:0006281	DNA repair

0.86	GO:0070876	SOSS complex
0.58	GO:0005654	nucleoplasm

tr|Q7ZV27|Q7ZV27_DANRE
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s
Search

ATP5S

0.95	Mitochondrial ATP synthase subunit s

0.49	GO:0006754	ATP biosynthetic process
0.45	GO:0015992	proton transport
0.41	GO:0042407	cristae formation
0.39	GO:0006839	mitochondrial transport
0.38	GO:0046907	intracellular transport
0.37	GO:0098662	inorganic cation transmembrane transport

0.41	GO:0046872	metal ion binding
0.37	GO:0015078	hydrogen ion transmembrane transporter activity

0.59	GO:0005739	mitochondrion
0.50	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.45	GO:0019866	organelle inner membrane

sp|Q7ZV34|MCTS1_DANRE
Malignant T-cell-amplified sequence 1
Search

0.10	Putative rna-binding protein (Fragment)

0.59

GO:0003723

RNA binding

0.46

GO:0005737

cytoplasm

sp|Q7ZV35|MED7_DANRE
Mediator of RNA polymerase II transcription subunit 7
Search

MED7

0.70	Mediator of RNA polymerase II transcription subunit 7-B

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.53	GO:0019827	stem cell population maintenance
0.37	GO:0016567	protein ubiquitination

0.78	GO:0001104	RNA polymerase II transcription cofactor activity
0.45	GO:0003713	transcription coactivator activity
0.37	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0005515	protein binding

0.77	GO:0016592	mediator complex
0.51	GO:0016604	nuclear body
0.50	GO:0005667	transcription factor complex
0.37	GO:0000151	ubiquitin ligase complex
0.34	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
0.30	GO:0031224	intrinsic component of membrane

tr|Q7ZV39|Q7ZV39_DANRE
Zgc:56235
Search

VDAC3

0.85	Voltage-dependent anion channel

0.83	GO:1902017	regulation of cilium assembly
0.69	GO:0098656	anion transmembrane transport
0.47	GO:0031101	fin regeneration
0.46	GO:0001662	behavioral fear response
0.46	GO:0007270	neuron-neuron synaptic transmission
0.45	GO:0007612	learning
0.41	GO:0036444	mitochondrial calcium uptake
0.40	GO:0008016	regulation of heart contraction
0.35	GO:0015853	adenine transport

0.78	GO:0008308	voltage-gated anion channel activity
0.38	GO:0042803	protein homodimerization activity
0.37	GO:0015288	porin activity
0.34	GO:1901265	nucleoside phosphate binding
0.34	GO:0036094	small molecule binding

0.78	GO:0005741	mitochondrial outer membrane
0.39	GO:0019866	organelle inner membrane
0.38	GO:0046930	pore complex
0.35	GO:0070062	extracellular exosome
0.35	GO:0005886	plasma membrane
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0008021	synaptic vesicle
0.33	GO:0005634	nucleus

sp|Q7ZV43|TOLIP_DANRE
Toll-interacting protein
Search

TOLLIP

0.95	Toll-interacting protein A

0.79	GO:0036010	protein localization to endosome
0.71	GO:0030855	epithelial cell differentiation
0.59	GO:0006954	inflammatory response
0.58	GO:0045087	innate immune response
0.57	GO:0006914	autophagy
0.56	GO:0006511	ubiquitin-dependent protein catabolic process
0.56	GO:0016310	phosphorylation
0.55	GO:0007165	signal transduction
0.49	GO:0033235	positive regulation of protein sumoylation
0.40	GO:0043312	neutrophil degranulation

0.80	GO:0035325	Toll-like receptor binding
0.70	GO:0019900	kinase binding
0.66	GO:0031624	ubiquitin conjugating enzyme binding
0.62	GO:0032182	ubiquitin-like protein binding
0.51	GO:0005150	interleukin-1, Type I receptor binding
0.46	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0004871	signal transducer activity

0.46	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0016604	nuclear body
0.44	GO:0070062	extracellular exosome
0.42	GO:0045092	interleukin-18 receptor complex
0.41	GO:0045323	interleukin-1 receptor complex
0.40	GO:0035580	specific granule lumen
0.40	GO:0035578	azurophil granule lumen
0.36	GO:0005829	cytosol

sp|Q7ZV46|METRL_DANRE
Meteorin-like protein
Search

METRNL

0.97	Meteorin like, glial cell differentiation regulator

0.80	GO:2000507	positive regulation of energy homeostasis
0.80	GO:0090336	positive regulation of brown fat cell differentiation
0.79	GO:0014850	response to muscle activity
0.74	GO:0050728	negative regulation of inflammatory response
0.74	GO:0045444	fat cell differentiation
0.71	GO:0009409	response to cold
0.66	GO:0010469	regulation of receptor activity
0.46	GO:0050772	positive regulation of axonogenesis
0.45	GO:0010001	glial cell differentiation

0.69

GO:0005179

hormone activity

0.67	GO:0005615	extracellular space
0.41	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

tr|Q7ZV49|Q7ZV49_DANRE
Hprt1 protein
Search

HPRT1

0.50	Hypoxanthine-guanine phosphoribosyltransferase

0.78	GO:0032264	IMP salvage
0.75	GO:0006166	purine ribonucleoside salvage
0.58	GO:0046038	GMP catabolic process
0.58	GO:0006178	guanine salvage
0.58	GO:0045964	positive regulation of dopamine metabolic process
0.54	GO:0051289	protein homotetramerization
0.54	GO:0007625	grooming behavior
0.54	GO:0046100	hypoxanthine metabolic process
0.54	GO:0021756	striatum development
0.54	GO:0001975	response to amphetamine

0.79	GO:0004422	hypoxanthine phosphoribosyltransferase activity
0.79	GO:0052657	guanine phosphoribosyltransferase activity
0.53	GO:0046872	metal ion binding
0.52	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.50	GO:0042803	protein homodimerization activity

0.48	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.33	GO:0005694	chromosome

0.79	EC:2.4.2.8	GO:0004422
0.79	KEGG:R01132	GO:0004422

sp|Q7ZV50|MAGT1_DANRE
Magnesium transporter protein 1
Search

MAGT1

0.95	Magnesium transporter protein 1

0.45	GO:0018279	protein N-linked glycosylation via asparagine
0.38	GO:0015693	magnesium ion transport
0.37	GO:0050890	cognition
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0098662	inorganic cation transmembrane transport

0.45	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity
0.36	GO:0015095	magnesium ion transmembrane transporter activity

0.44	GO:0008250	oligosaccharyltransferase complex
0.35	GO:0005886	plasma membrane
0.35	GO:0035577	azurophil granule membrane
0.30	GO:0031224	intrinsic component of membrane

0.45

EC:2.4.1.119

GO:0004579

sp|Q7ZV55|EIF3I_DANRE
Eukaryotic translation initiation factor 3 subunit I
Search

EIF3I

0.68	Eukaryotic translation initiation factor 3 subunit I

0.72	GO:0006413	translational initiation
0.68	GO:0002181	cytoplasmic translation
0.68	GO:0006446	regulation of translational initiation
0.64	GO:0022618	ribonucleoprotein complex assembly
0.45	GO:0002040	sprouting angiogenesis
0.45	GO:0001889	liver development
0.35	GO:0035556	intracellular signal transduction

0.73	GO:0003743	translation initiation factor activity
0.35	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.78	GO:0005852	eukaryotic translation initiation factor 3 complex
0.69	GO:0016282	eukaryotic 43S preinitiation complex
0.69	GO:0033290	eukaryotic 48S preinitiation complex
0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol

tr|Q7ZV59|Q7ZV59_DANRE
Synaptojanin 2-binding protein
Search

SYNJ2BP

0.97	Putative pdz domain containing protein found in a variety of eumetazoan signaling molecules

0.52	GO:1903671	negative regulation of sprouting angiogenesis
0.51	GO:0001937	negative regulation of endothelial cell proliferation
0.51	GO:0010596	negative regulation of endothelial cell migration
0.51	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.50	GO:0008593	regulation of Notch signaling pathway
0.46	GO:0007266	Rho protein signal transduction
0.46	GO:0030100	regulation of endocytosis
0.42	GO:0006605	protein targeting
0.40	GO:0048312	intracellular distribution of mitochondria
0.37	GO:0032927	positive regulation of activin receptor signaling pathway

0.39	GO:0008022	protein C-terminus binding
0.38	GO:0070699	type II activin receptor binding
0.34	GO:0005272	sodium channel activity
0.32	GO:0016301	kinase activity

0.44	GO:0005739	mitochondrion
0.40	GO:0031967	organelle envelope
0.40	GO:0031090	organelle membrane
0.38	GO:0098805	whole membrane
0.37	GO:0019867	outer membrane
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0009986	cell surface
0.35	GO:0005911	cell-cell junction
0.30	GO:0016021	integral component of membrane

sp|Q7ZV60|BCS1_DANRE
Mitochondrial chaperone BCS1
Search

BCS1L

0.78	BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone

0.84	GO:0017062	respiratory chain complex III assembly
0.84	GO:0097033	mitochondrial respiratory chain complex III biogenesis
0.81	GO:0033108	mitochondrial respiratory chain complex assembly
0.54	GO:0097031	mitochondrial respiratory chain complex I biogenesis
0.54	GO:0010257	NADH dehydrogenase complex assembly
0.53	GO:0097034	mitochondrial respiratory chain complex IV biogenesis
0.53	GO:0008535	respiratory chain complex IV assembly
0.33	GO:0055114	oxidation-reduction process

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.34	GO:0020037	heme binding
0.34	GO:0005506	iron ion binding
0.33	GO:0005515	protein binding

0.61	GO:0005739	mitochondrion
0.36	GO:0019866	organelle inner membrane
0.34	GO:0045275	respiratory chain complex III
0.30	GO:0016021	integral component of membrane

0.34

EC:1.14

GO:0016705

sp|Q7ZV68|VPS29_DANRE
Vacuolar protein sorting-associated protein 29
Search

VPS29

0.72	Vacuolar protein sorting-associated protein 29

0.81	GO:0042147	retrograde transport, endosome to Golgi
0.65	GO:0015031	protein transport
0.42	GO:0034613	cellular protein localization
0.40	GO:1990126	retrograde transport, endosome to plasma membrane
0.35	GO:0010506	regulation of autophagy
0.34	GO:0006896	Golgi to vacuole transport
0.34	GO:0016055	Wnt signaling pathway

0.42	GO:0008565	protein transporter activity
0.40	GO:0008270	zinc ion binding
0.34	GO:0005515	protein binding
0.33	GO:0016787	hydrolase activity

0.82	GO:0030904	retromer complex
0.68	GO:0005829	cytosol
0.45	GO:0005768	endosome
0.40	GO:0044433	cytoplasmic vesicle part
0.39	GO:0098805	whole membrane
0.39	GO:0098588	bounding membrane of organelle
0.39	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016787

tr|Q7ZV77|Q7ZV77_DANRE
Proteasome subunit alpha type
Search

PSMA4

0.49	Proteasome endopeptidase complex

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.71	GO:0043632	modification-dependent macromolecule catabolic process
0.36	GO:0010608	posttranscriptional regulation of gene expression
0.36	GO:0032269	negative regulation of cellular protein metabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0034249	negative regulation of cellular amide metabolic process
0.35	GO:0006879	cellular iron ion homeostasis
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway

0.77	GO:0004298	threonine-type endopeptidase activity
0.37	GO:0030350	iron-responsive element binding
0.36	GO:0030371	translation repressor activity
0.33	GO:0005515	protein binding
0.32	GO:0016301	kinase activity

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.60	GO:0005634	nucleus
0.50	GO:0000932	P-body
0.47	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.77

EC:3.4.25

GO:0004298

sp|Q7ZV79|UCK2B_DANRE
Uridine-cytidine kinase 2-B
Search

UCK2

0.87	Uridine-cytidine kinase

0.83	GO:0006238	CMP salvage
0.77	GO:0044206	UMP salvage
0.71	GO:0044211	CTP salvage
0.57	GO:0016310	phosphorylation
0.45	GO:0006206	pyrimidine nucleobase metabolic process
0.35	GO:0048678	response to axon injury
0.34	GO:0007631	feeding behavior
0.34	GO:0071453	cellular response to oxygen levels
0.34	GO:0016579	protein deubiquitination

0.77	GO:0019206	nucleoside kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.44	GO:0005829	cytosol
0.32	GO:0043231	intracellular membrane-bounded organelle

sp|Q7ZV80|SPF30_DANRE
Survival of motor neuron-related-splicing factor 30
Search

SMNDC1

0.95	Survival motor neuron domain containing 1

0.66	GO:0006397	mRNA processing
0.40	GO:0008380	RNA splicing
0.39	GO:0006915	apoptotic process

0.56	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.58	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.38	GO:0070013	intracellular organelle lumen
0.37	GO:1990904	ribonucleoprotein complex
0.36	GO:0044446	intracellular organelle part

sp|Q7ZV82|RL27_DANRE
60S ribosomal protein L27
Search

RPL27

0.75	60S ribosomal protein L27

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.44	GO:0030218	erythrocyte differentiation
0.42	GO:0016072	rRNA metabolic process
0.42	GO:0042254	ribosome biogenesis
0.35	GO:1904044	response to aldosterone
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.63	GO:0003735	structural constituent of ribosome
0.33	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.46	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.44	GO:0044445	cytosolic part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus

0.32

GO:0016787

sp|Q7ZV84|DAAF1_DANRE
Dynein assembly factor 1, axonemal
Search

DNAAF1

0.80	Dynein assembly factor 1, axonemal

0.85	GO:0044458	motile cilium assembly
0.54	GO:0035469	determination of pancreatic left/right asymmetry
0.54	GO:0071910	determination of liver left/right asymmetry
0.54	GO:0003356	regulation of cilium beat frequency
0.54	GO:0071907	determination of digestive tract left/right asymmetry
0.53	GO:0036158	outer dynein arm assembly
0.53	GO:0001947	heart looping
0.53	GO:0060972	left/right pattern formation
0.53	GO:0036159	inner dynein arm assembly
0.51	GO:0030324	lung development

0.55	GO:0070840	dynein complex binding
0.34	GO:0005230	extracellular ligand-gated ion channel activity
0.33	GO:0004888	transmembrane signaling receptor activity

0.76	GO:0005929	cilium
0.53	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.50	GO:0016607	nuclear speck
0.48	GO:0044430	cytoskeletal part
0.45	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.34	GO:0015630	microtubule cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

sp|Q7ZV90|PIF1_DANRE
ATP-dependent DNA helicase PIF1
Search

PIF1

0.46	ATP-dependent DNA helicase

0.78	GO:0000723	telomere maintenance
0.76	GO:0000002	mitochondrial genome maintenance
0.70	GO:0032392	DNA geometric change
0.65	GO:0006281	DNA repair
0.64	GO:0006310	DNA recombination
0.61	GO:0032211	negative regulation of telomere maintenance via telomerase
0.61	GO:0051974	negative regulation of telomerase activity
0.42	GO:0006260	DNA replication

0.75	GO:0043141	ATP-dependent 5'-3' DNA helicase activity
0.61	GO:0010521	telomerase inhibitor activity
0.57	GO:0051880	G-quadruplex DNA binding
0.56	GO:0033678	5'-3' DNA/RNA helicase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0033680	ATP-dependent DNA/RNA helicase activity
0.51	GO:0042162	telomeric DNA binding

0.58	GO:0005634	nucleus
0.57	GO:0005739	mitochondrion
0.50	GO:0000781	chromosome, telomeric region
0.45	GO:0070013	intracellular organelle lumen
0.45	GO:0005657	replication fork

0.75

EC:3.6.1

GO:0043141

tr|Q7ZV92|Q7ZV92_DANRE
PRP19/PSO4 homolog (S. cerevisiae)
Search

PRPF19

0.91	pre-mRNA-processing factor 19

0.71	GO:0016567	protein ubiquitination
0.54	GO:0048711	positive regulation of astrocyte differentiation
0.54	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.54	GO:0072422	signal transduction involved in DNA damage checkpoint
0.53	GO:0000244	spliceosomal tri-snRNP complex assembly
0.52	GO:0001833	inner cell mass cell proliferation
0.52	GO:0045665	negative regulation of neuron differentiation
0.51	GO:0000245	spliceosomal complex assembly
0.51	GO:0006303	double-strand break repair via nonhomologous end joining
0.50	GO:0000349	generation of catalytic spliceosome for first transesterification step

0.72	GO:0004842	ubiquitin-protein transferase activity
0.50	GO:0061659	ubiquitin-like protein ligase activity
0.48	GO:0042802	identical protein binding

0.56	GO:0000974	Prp19 complex
0.54	GO:0005684	U2-type spliceosomal complex
0.54	GO:0005662	DNA replication factor A complex
0.52	GO:0035861	site of double-strand break
0.52	GO:0005811	lipid droplet
0.51	GO:0071013	catalytic step 2 spliceosome
0.51	GO:0016607	nuclear speck
0.49	GO:0071012	catalytic step 1 spliceosome
0.38	GO:0005819	spindle
0.38	GO:0005737	cytoplasm

0.72

GO:0004842

tr|Q7ZV93|Q7ZV93_DANRE
GAIP c-terminus interacting protein 2
Search

GIPC1

0.95	GAIP c-terminus interacting protein 2

0.72	GO:0014047	glutamate secretion
0.69	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.68	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.67	GO:0043542	endothelial cell migration
0.66	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.66	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
0.66	GO:0048167	regulation of synaptic plasticity
0.66	GO:0032467	positive regulation of cytokinesis
0.63	GO:0031647	regulation of protein stability
0.62	GO:0007268	chemical synaptic transmission

0.67	GO:0017022	myosin binding
0.64	GO:0045296	cadherin binding
0.62	GO:0042802	identical protein binding
0.59	GO:0003779	actin binding
0.58	GO:0005102	receptor binding
0.56	GO:0046983	protein dimerization activity
0.52	GO:0004707	MAP kinase activity
0.45	GO:0030165	PDZ domain binding
0.41	GO:0051082	unfolded protein binding
0.40	GO:0004957	prostaglandin E receptor activity

0.68	GO:0043198	dendritic shaft
0.67	GO:0043197	dendritic spine
0.64	GO:0008021	synaptic vesicle
0.61	GO:0012506	vesicle membrane
0.60	GO:0005938	cell cortex
0.56	GO:0005829	cytosol
0.45	GO:0005903	brush border
0.44	GO:0030139	endocytic vesicle
0.40	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.52	EC:2.7.11.24	GO:0004707
0.52	KEGG:R00162	GO:0004707

tr|Q7ZV94|Q7ZV94_DANRE
MOB kinase activator 1Ba
Search

MOB1B

0.96	MOB kinase activator 1B protein 2

0.62	GO:0035329	hippo signaling
0.57	GO:0031952	regulation of protein autophosphorylation
0.52	GO:0042327	positive regulation of phosphorylation
0.50	GO:0016310	phosphorylation

0.55	GO:0019209	kinase activator activity
0.53	GO:0019900	kinase binding
0.52	GO:0016301	kinase activity
0.35	GO:0046872	metal ion binding

0.55	GO:0005730	nucleolus
0.52	GO:0005829	cytosol
0.39	GO:0070062	extracellular exosome

tr|Q7ZV96|Q7ZV96_DANRE
QM protein
Search

RPL10

0.44	Ribosomal protein 10

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.52	GO:1990403	embryonic brain development
0.48	GO:0000027	ribosomal large subunit assembly
0.47	GO:0007283	spermatogenesis
0.45	GO:0006417	regulation of translation
0.43	GO:0007420	brain development
0.38	GO:0043066	negative regulation of apoptotic process

0.64	GO:0003735	structural constituent of ribosome
0.49	GO:0045182	translation regulator activity
0.41	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.50	GO:0044445	cytosolic part
0.49	GO:0005783	endoplasmic reticulum
0.46	GO:0005844	polysome
0.43	GO:0044446	intracellular organelle part
0.42	GO:0005634	nucleus
0.35	GO:0043234	protein complex
0.34	GO:0098562	cytoplasmic side of membrane
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle

0.32

GO:0016787

sp|Q7ZVA0|SMU1_DANRE
WD40 repeat-containing protein SMU1
Search

SMU1

0.94	DNA replication regulator and spliceosomal factor

0.79	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.69	GO:0008380	RNA splicing
0.65	GO:0006397	mRNA processing
0.45	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.40	GO:0006468	protein phosphorylation

0.47	GO:0016905	myosin heavy chain kinase activity
0.44	GO:0031683	G-protein beta/gamma-subunit complex binding
0.41	GO:0003924	GTPase activity
0.40	GO:0032550	purine ribonucleoside binding
0.40	GO:0019001	guanyl nucleotide binding
0.40	GO:0004871	signal transducer activity
0.37	GO:0032555	purine ribonucleotide binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.75	GO:0016607	nuclear speck
0.69	GO:0005681	spliceosomal complex
0.47	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.47

EC:2.7.11.7

GO:0016905

tr|Q7ZVA2|Q7ZVA2_DANRE
RAS (RAD and GEM)-like GTP-binding 1
Search

0.86	GTP binding protein overexpressed in skeletal muscle

0.85	GO:1901841	regulation of high voltage-gated calcium channel activity
0.83	GO:1901386	negative regulation of voltage-gated calcium channel activity
0.61	GO:0007165	signal transduction
0.46	GO:0051310	metaphase plate congression
0.43	GO:0000278	mitotic cell cycle
0.40	GO:0051276	chromosome organization
0.34	GO:0006955	immune response

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0005246	calcium channel regulator activity
0.40	GO:0000287	magnesium ion binding
0.35	GO:0005516	calmodulin binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0008144	drug binding

0.46	GO:0051233	spindle midzone
0.45	GO:0030496	midbody
0.45	GO:0072686	mitotic spindle
0.43	GO:0009898	cytoplasmic side of plasma membrane
0.39	GO:0005634	nucleus

tr|Q7ZVA4|Q7ZVA4_DANRE
Protein S100
Search

S100A10

0.92	S100 calcium binding protein (Fragment)

0.63	GO:0042127	regulation of cell proliferation
0.49	GO:0051894	positive regulation of focal adhesion assembly
0.49	GO:0051290	protein heterotetramerization
0.49	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.49	GO:0051496	positive regulation of stress fiber assembly
0.49	GO:0001765	membrane raft assembly
0.47	GO:0072659	protein localization to plasma membrane
0.47	GO:0006900	vesicle budding from membrane
0.46	GO:0051099	positive regulation of binding
0.45	GO:0043547	positive regulation of GTPase activity

0.71	GO:0048306	calcium-dependent protein binding
0.69	GO:0005509	calcium ion binding
0.48	GO:0044325	ion channel binding
0.47	GO:0042803	protein homodimerization activity
0.37	GO:0050786	RAGE receptor binding
0.36	GO:0045296	cadherin binding
0.35	GO:0008289	lipid binding
0.34	GO:0046914	transition metal ion binding

0.47	GO:0045121	membrane raft
0.44	GO:0019897	extrinsic component of plasma membrane
0.42	GO:0005576	extracellular region
0.39	GO:0005634	nucleus
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0031982	vesicle
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

sp|Q7ZVA6|IF4A3_DANRE
Eukaryotic initiation factor 4A-III
Search

EIF4A3

0.87	Eukaryotic initiation factor

0.61	GO:0006413	translational initiation
0.53	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.51	GO:0048701	embryonic cranial skeleton morphogenesis
0.48	GO:0006417	regulation of translation
0.48	GO:0034250	positive regulation of cellular amide metabolic process
0.47	GO:0034249	negative regulation of cellular amide metabolic process
0.47	GO:0010501	RNA secondary structure unwinding
0.46	GO:0032270	positive regulation of cellular protein metabolic process
0.46	GO:0008380	RNA splicing
0.46	GO:0048024	regulation of mRNA splicing, via spliceosome

0.65	GO:0004386	helicase activity
0.61	GO:0003743	translation initiation factor activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0008143	poly(A) binding
0.49	GO:0008186	RNA-dependent ATPase activity
0.47	GO:0003729	mRNA binding
0.43	GO:0140098	catalytic activity, acting on RNA

0.51	GO:0071013	catalytic step 2 spliceosome
0.51	GO:0035145	exon-exon junction complex
0.47	GO:0005654	nucleoplasm
0.44	GO:0005730	nucleolus
0.39	GO:0005737	cytoplasm
0.36	GO:0043025	neuronal cell body
0.36	GO:0030425	dendrite
0.30	GO:0016020	membrane

sp|Q7ZVB1|CHM1B_DANRE
Charged multivesicular body protein 1b
Search

CHMP1B

0.94	Charged multivesicular body protein 1b

0.79	GO:0007034	vacuolar transport
0.42	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.41	GO:1901673	regulation of mitotic spindle assembly
0.41	GO:0000920	cell separation after cytokinesis
0.41	GO:0007080	mitotic metaphase plate congression
0.41	GO:0010824	regulation of centrosome duplication
0.40	GO:0006997	nucleus organization
0.40	GO:0039702	viral budding via host ESCRT complex
0.39	GO:0045184	establishment of protein localization
0.38	GO:0042886	amide transport

0.39	GO:0019904	protein domain specific binding
0.39	GO:0042802	identical protein binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005768	endosome
0.42	GO:0044433	cytoplasmic vesicle part
0.42	GO:0098805	whole membrane
0.41	GO:0098588	bounding membrane of organelle
0.40	GO:0045177	apical part of cell
0.40	GO:0030496	midbody
0.39	GO:0030117	membrane coat
0.38	GO:0005829	cytosol
0.36	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome

sp|Q7ZVB2|A9A1A_DANRE
Aldehyde dehydrogenase family 9 member A1-A
Search

ALDH9A1

0.80	4-trimethylaminobutyraldehyde dehydrogenase

0.53	GO:0055114	oxidation-reduction process
0.48	GO:0042136	neurotransmitter biosynthetic process
0.45	GO:0006081	cellular aldehyde metabolic process
0.45	GO:0045329	carnitine biosynthetic process
0.37	GO:0001889	liver development
0.36	GO:0001822	kidney development
0.36	GO:0042445	hormone metabolic process

0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.37	GO:0033737	1-pyrroline dehydrogenase activity
0.37	GO:0043176	amine binding
0.36	GO:0042803	protein homodimerization activity
0.35	GO:0051287	NAD binding

0.39	GO:0070062	extracellular exosome
0.38	GO:0005829	cytosol
0.35	GO:0005739	mitochondrion

0.69

GO:0016620

tr|Q7ZVB5|Q7ZVB5_DANRE
Small nuclear ribonucleoprotein D3 polypeptide, like
Search

SNRPD3

0.88	Small nuclear ribonucleoprotein D3 polypeptide

0.81	GO:0000387	spliceosomal snRNP assembly
0.48	GO:0008213	protein alkylation
0.46	GO:0000245	spliceosomal complex assembly
0.45	GO:0043414	macromolecule methylation
0.35	GO:0008334	histone mRNA metabolic process
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0045451	pole plasm oskar mRNA localization
0.34	GO:0048542	lymph gland development
0.34	GO:0007422	peripheral nervous system development
0.34	GO:0007517	muscle organ development

0.56	GO:0071209	U7 snRNA binding
0.55	GO:0071208	histone pre-mRNA DCP binding
0.55	GO:0030620	U2 snRNA binding
0.54	GO:0070034	telomerase RNA binding
0.47	GO:0019899	enzyme binding
0.39	GO:1990446	U1 snRNP binding

0.76	GO:0005681	spliceosomal complex
0.62	GO:0019013	viral nucleocapsid
0.56	GO:0005687	U4 snRNP
0.56	GO:0034715	pICln-Sm protein complex
0.56	GO:0034719	SMN-Sm protein complex
0.55	GO:0005683	U7 snRNP
0.54	GO:0034709	methylosome
0.53	GO:0005697	telomerase holoenzyme complex
0.53	GO:0005685	U1 snRNP
0.50	GO:0016604	nuclear body

sp|Q7ZVC2|CLUA1_DANRE
Clusterin-associated protein 1 homolog
Search

CLUAP1

0.75	clusterin-associated protein 1

0.65	GO:0060271	cilium assembly
0.57	GO:0021508	floor plate formation
0.55	GO:0060972	left/right pattern formation
0.55	GO:0048513	animal organ development
0.53	GO:0001843	neural tube closure
0.53	GO:0042073	intraciliary transport
0.53	GO:0007368	determination of left/right symmetry
0.53	GO:0007224	smoothened signaling pathway
0.53	GO:0001578	microtubule bundle formation
0.51	GO:0045494	photoreceptor cell maintenance

0.40

GO:0005515

protein binding

0.68	GO:0030992	intraciliary transport particle B
0.65	GO:0005929	cilium
0.64	GO:0005813	centrosome
0.59	GO:0005654	nucleoplasm
0.54	GO:0120038	plasma membrane bounded cell projection part
0.49	GO:0099568	cytoplasmic region
0.30	GO:0031224	intrinsic component of membrane

sp|Q7ZVC4|CHM4B_DANRE
Charged multivesicular body protein 4b
Search

CHMP4B

0.89	Charged multivesicular body protein 4Ba

0.79	GO:0007034	vacuolar transport
0.56	GO:0036438	maintenance of lens transparency
0.56	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
0.55	GO:0090148	membrane fission
0.55	GO:0010458	exit from mitosis
0.55	GO:0031468	nuclear envelope reassembly
0.55	GO:1902902	negative regulation of autophagosome assembly
0.55	GO:1902188	positive regulation of viral release from host cell
0.54	GO:1901673	regulation of mitotic spindle assembly
0.53	GO:0000920	cell separation after cytokinesis

0.51	GO:0045296	cadherin binding
0.49	GO:0042803	protein homodimerization activity
0.33	GO:0003700	DNA binding transcription factor activity

0.55	GO:0000815	ESCRT III complex
0.53	GO:0030496	midbody
0.50	GO:0005635	nuclear envelope
0.49	GO:0009898	cytoplasmic side of plasma membrane
0.49	GO:0048475	coated membrane
0.46	GO:0005829	cytosol
0.41	GO:0031902	late endosome membrane
0.34	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q7ZVC9|SMAP_DANRE
Small acidic protein
Search

SMAP

0.96	small acidic protein isoform X1

tr|Q7ZVD4|Q7ZVD4_DANRE
Sf3a2 protein
Search

SF3A2

0.81	Splicing factor 3A subunit

0.46	GO:0006397	mRNA processing
0.42	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
0.42	GO:0022618	ribonucleoprotein complex assembly
0.37	GO:0008406	gonad development
0.36	GO:0010469	regulation of receptor activity
0.35	GO:0010976	positive regulation of neuron projection development

0.61	GO:0008270	zinc ion binding
0.50	GO:0003676	nucleic acid binding
0.36	GO:0008083	growth factor activity

0.59	GO:0005634	nucleus
0.43	GO:1902494	catalytic complex
0.43	GO:0120114	Sm-like protein family complex
0.43	GO:0030529	intracellular ribonucleoprotein complex
0.41	GO:0044446	intracellular organelle part
0.34	GO:0005576	extracellular region
0.34	GO:0031974	membrane-enclosed lumen

tr|Q7ZVD8|Q7ZVD8_DANRE
ADP-ribosylation factor-like 11
Search

0.66	ADP-ribosylation factor J

0.38	GO:0048699	generation of neurons
0.38	GO:0048638	regulation of developmental growth
0.38	GO:0001558	regulation of cell growth
0.37	GO:0008361	regulation of cell size
0.37	GO:0010769	regulation of cell morphogenesis involved in differentiation
0.37	GO:0050920	regulation of chemotaxis
0.36	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.36	GO:0060271	cilium assembly
0.36	GO:0051960	regulation of nervous system development
0.36	GO:0051270	regulation of cellular component movement

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0005515	protein binding
0.32	GO:0016757	transferase activity, transferring glycosyl groups
0.32	GO:0003924	GTPase activity

0.45	GO:0005622	intracellular
0.36	GO:0120025	plasma membrane bounded cell projection
0.35	GO:0032155	cell division site part
0.35	GO:0031982	vesicle
0.35	GO:0030428	cell septum
0.35	GO:0051286	cell tip
0.34	GO:0048786	presynaptic active zone
0.34	GO:0012505	endomembrane system
0.33	GO:0097610	cell surface furrow
0.33	GO:0071944	cell periphery

0.32

EC:2.4

GO:0016757

sp|Q7ZVE0|GAR1_DANRE
H/ACA ribonucleoprotein complex subunit 1
Search

GAR1

0.70	H/ACA ribonucleoprotein complex subunit

0.71	GO:0001522	pseudouridine synthesis
0.66	GO:0042254	ribosome biogenesis
0.66	GO:0016072	rRNA metabolic process
0.62	GO:0034470	ncRNA processing
0.50	GO:0016074	snoRNA metabolic process
0.38	GO:0007601	visual perception
0.37	GO:0018298	protein-chromophore linkage
0.37	GO:0007186	G-protein coupled receptor signaling pathway
0.37	GO:0060216	definitive hemopoiesis
0.36	GO:0007004	telomere maintenance via telomerase

0.60	GO:0034513	box H/ACA snoRNA binding
0.57	GO:0070034	telomerase RNA binding
0.38	GO:0009881	photoreceptor activity
0.37	GO:0004930	G-protein coupled receptor activity
0.34	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0030619	U1 snRNA binding
0.32	GO:0004386	helicase activity
0.32	GO:0003729	mRNA binding
0.32	GO:0008168	methyltransferase activity

0.83	GO:0031429	box H/ACA snoRNP complex
0.58	GO:0090661	box H/ACA telomerase RNP complex
0.58	GO:0019013	viral nucleocapsid
0.55	GO:0001650	fibrillar center
0.54	GO:0000784	nuclear chromosome, telomeric region
0.37	GO:0015030	Cajal body
0.33	GO:0001651	dense fibrillar component
0.32	GO:0071011	precatalytic spliceosome
0.32	GO:0000243	commitment complex
0.32	GO:0071004	U2-type prespliceosome

0.32

GO:0008168

sp|Q7ZVE3|TIGRB_DANRE
Fructose-2,6-bisphosphatase TIGAR B
Search

0.91	Tp53-induced glycolysis and apoptosis regulator b

0.59	GO:1902151	regulation of response to DNA integrity checkpoint signaling
0.59	GO:1902689	negative regulation of NAD metabolic process
0.58	GO:1901003	negative regulation of fermentation
0.58	GO:1904023	regulation of glucose catabolic process to lactate via pyruvate
0.58	GO:0071279	cellular response to cobalt ion
0.58	GO:0006003	fructose 2,6-bisphosphate metabolic process
0.58	GO:1903301	positive regulation of hexokinase activity
0.57	GO:1901525	negative regulation of mitophagy
0.57	GO:0010666	positive regulation of cardiac muscle cell apoptotic process
0.57	GO:0043456	regulation of pentose-phosphate shunt

0.62	GO:0004083	bisphosphoglycerate 2-phosphatase activity
0.60	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity
0.36	GO:0004619	phosphoglycerate mutase activity
0.35	GO:0043755	alpha-ribazole phosphatase activity
0.35	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0019901	protein kinase binding
0.33	GO:0004647	phosphoserine phosphatase activity

0.54	GO:0005741	mitochondrial outer membrane
0.51	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.35	GO:0097129	cyclin D2-CDK4 complex
0.34	GO:0000785	chromatin
0.33	GO:0012505	endomembrane system
0.33	GO:0070013	intracellular organelle lumen
0.30	GO:0016021	integral component of membrane

0.62	EC:3.1.3.13	GO:0004083
0.62	KEGG:R01516	GO:0004083

tr|Q7ZVE5|Q7ZVE5_DANRE
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (Subunit 9)
Search

0.88	ATP synthase lipid-binding protein, mitochondrial

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.38	GO:0045471	response to ethanol
0.36	GO:0042407	cristae formation
0.35	GO:0006839	mitochondrial transport
0.34	GO:0046907	intracellular transport
0.34	GO:0007568	aging
0.33	GO:0055114	oxidation-reduction process

0.71	GO:0008289	lipid binding
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.44	GO:0019829	cation-transporting ATPase activity
0.44	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.36	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.35	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.33	GO:0005515	protein binding

0.72	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.47	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.34	GO:0005741	mitochondrial outer membrane
0.30	GO:0016021	integral component of membrane

0.36

EC:1.1.1.42

GO:0004450

sp|Q7ZVE6|KDEL1_DANRE
KDEL motif-containing protein 1
Search

KDELC1

0.95	KDEL motif-containing protein 1

0.59

GO:0006664

glycolipid metabolic process

0.62

GO:0046527

glucosyltransferase activity

0.83	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

0.62

GO:0046527

tr|Q7ZVE9|Q7ZVE9_DANRE
Procollagen-proline, 2-oxoglutarate 4-dioxygenase (Proline 4-hydroxylase), alpha polypeptide I
Search

P4HA1

0.76	Procollagen-proline 2-oxoglutarate-4-dioxygenase

0.84	GO:0019511	peptidyl-proline hydroxylation
0.53	GO:0055114	oxidation-reduction process
0.47	GO:0019471	4-hydroxyproline metabolic process
0.46	GO:0030199	collagen fibril organization
0.34	GO:0050482	arachidonic acid secretion
0.33	GO:0016042	lipid catabolic process
0.33	GO:0006644	phospholipid metabolic process

0.85	GO:0004656	procollagen-proline 4-dioxygenase activity
0.79	GO:0031418	L-ascorbic acid binding
0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.63	GO:0005506	iron ion binding
0.47	GO:0042802	identical protein binding
0.34	GO:0004623	phospholipase A2 activity
0.33	GO:0005509	calcium ion binding

0.70	GO:0005783	endoplasmic reticulum
0.42	GO:0005739	mitochondrion
0.41	GO:1990204	oxidoreductase complex
0.39	GO:0044446	intracellular organelle part
0.36	GO:0043233	organelle lumen
0.35	GO:0005581	collagen trimer
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.85	EC:1.14.11.2	GO:0004656
0.85	KEGG:R03219	GO:0004656

sp|Q7ZVF0|POC1A_DANRE
POC1 centriolar protein homolog A
Search

POC1A

0.97	POC1 centriolar protein like protein A

0.85	GO:0003431	growth plate cartilage chondrocyte development
0.83	GO:0010825	positive regulation of centrosome duplication
0.78	GO:1905515	non-motile cilium assembly
0.77	GO:0007052	mitotic spindle organization
0.74	GO:0007283	spermatogenesis
0.40	GO:0007634	optokinetic behavior
0.40	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry
0.40	GO:0010842	retina layer formation
0.39	GO:0051781	positive regulation of cell division
0.39	GO:0003014	renal system process

0.36

GO:0005515

protein binding

0.79	GO:0036064	ciliary basal body
0.78	GO:0005814	centriole
0.75	GO:0000922	spindle pole
0.74	GO:0005813	centrosome

tr|Q7ZVF1|Q7ZVF1_DANRE
Chitinase, acidic.1
Search

0.46	Myeloid cell lineage chitinase

0.74	GO:0006030	chitin metabolic process
0.60	GO:0005975	carbohydrate metabolic process
0.47	GO:1901072	glucosamine-containing compound catabolic process
0.44	GO:0006026	aminoglycan catabolic process
0.43	GO:0042737	drug catabolic process
0.40	GO:0090197	positive regulation of chemokine secretion
0.39	GO:0002532	production of molecular mediator involved in inflammatory response
0.37	GO:2000360	negative regulation of binding of sperm to zona pellucida
0.36	GO:0007338	single fertilization
0.35	GO:0006915	apoptotic process

0.77	GO:0008061	chitin binding
0.63	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.37	GO:0019900	kinase binding
0.35	GO:0046982	protein heterodimerization activity
0.34	GO:0003743	translation initiation factor activity

0.63	GO:0005576	extracellular region
0.37	GO:0035805	egg coat
0.35	GO:0030133	transport vesicle
0.30	GO:0016020	membrane

0.63

EC:3.2.1

GO:0004553

tr|Q7ZVF2|Q7ZVF2_DANRE
Glutamine synthetase
Search

GLUL

0.46	Glutamine synthetase

0.76	GO:0006542	glutamine biosynthetic process
0.48	GO:0008283	cell proliferation
0.47	GO:0009749	response to glucose
0.46	GO:0031667	response to nutrient levels
0.43	GO:0031668	cellular response to extracellular stimulus
0.41	GO:0033554	cellular response to stress
0.38	GO:0051968	positive regulation of synaptic transmission, glutamatergic
0.38	GO:0019676	ammonia assimilation cycle
0.37	GO:0032024	positive regulation of insulin secretion
0.37	GO:0050679	positive regulation of epithelial cell proliferation

0.76	GO:0004356	glutamate-ammonia ligase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0042802	identical protein binding
0.41	GO:0004351	glutamate decarboxylase activity
0.38	GO:0016595	glutamate binding
0.38	GO:0045503	dynein light chain binding
0.36	GO:0030145	manganese ion binding
0.35	GO:0000287	magnesium ion binding

0.49	GO:0097386	glial cell projection
0.47	GO:0043209	myelin sheath
0.46	GO:0044297	cell body
0.44	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.37	GO:0043679	axon terminus
0.37	GO:0005791	rough endoplasmic reticulum
0.37	GO:0036477	somatodendritic compartment
0.34	GO:0070062	extracellular exosome
0.34	GO:0043234	protein complex

0.76	EC:6.3.1.2	GO:0004356
0.76	KEGG:R00253	GO:0004356

sp|Q7ZVF3|SDHA_DANRE
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Search

SDHA

0.68	Succinate dehydrogenase [ubiquinone] flavoprotein subunit A, mitochondrial

0.70	GO:0006099	tricarboxylic acid cycle
0.60	GO:0022900	electron transport chain
0.51	GO:0006105	succinate metabolic process
0.46	GO:0007399	nervous system development
0.44	GO:0009061	anaerobic respiration
0.40	GO:0006119	oxidative phosphorylation
0.36	GO:0006106	fumarate metabolic process
0.34	GO:0007034	vacuolar transport

0.79	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.40	GO:0009055	electron transfer activity
0.36	GO:0004333	fumarate hydratase activity
0.35	GO:0005515	protein binding

0.57	GO:0031966	mitochondrial membrane
0.57	GO:0019866	organelle inner membrane
0.49	GO:0045282	plasma membrane succinate dehydrogenase complex
0.48	GO:0045257	succinate dehydrogenase complex (ubiquinone)
0.48	GO:0045283	fumarate reductase complex
0.48	GO:0043209	myelin sheath
0.46	GO:0005730	nucleolus
0.44	GO:0098798	mitochondrial protein complex
0.36	GO:0045239	tricarboxylic acid cycle enzyme complex
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:1.3.5.1	GO:0008177
0.79	KEGG:R02164	GO:0008177

sp|Q7ZVF9|ACTB2_DANRE
Actin, cytoplasmic 2
Search

ACTB

0.64	Cytoskeletal beta-actin

0.49	GO:0030554	adenyl nucleotide binding
0.49	GO:0097367	carbohydrate derivative binding
0.49	GO:0008144	drug binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding

0.67	GO:0097433	dense body
0.62	GO:0005925	focal adhesion
0.55	GO:0005856	cytoskeleton
0.46	GO:0005886	plasma membrane
0.36	GO:0005634	nucleus

tr|Q7ZVG4|Q7ZVG4_DANRE
C20orf45 homolog (H. sapiens)
Search

0.97	PRELI domain containing 3

0.45

GO:0015914

phospholipid transport

0.49

GO:1990050

phosphatidic acid transporter activity

0.79

GO:0005758

mitochondrial intermembrane space

sp|Q7ZVG6|SIAH1_DANRE
E3 ubiquitin-protein ligase Siah1
Search

SIAH1

0.56	E3 ubiquitin-protein ligase

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.72	GO:0016567	protein ubiquitination
0.70	GO:0007275	multicellular organism development
0.55	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.41	GO:0051402	neuron apoptotic process
0.38	GO:0010498	proteasomal protein catabolic process
0.38	GO:0031648	protein destabilization
0.37	GO:0007283	spermatogenesis
0.37	GO:0007141	male meiosis I
0.36	GO:0040014	regulation of multicellular organism growth

0.63	GO:0008270	zinc ion binding
0.53	GO:0008022	protein C-terminus binding
0.52	GO:0016874	ligase activity
0.50	GO:0061630	ubiquitin protein ligase activity
0.49	GO:0042802	identical protein binding
0.36	GO:0097718	disordered domain specific binding
0.34	GO:0046983	protein dimerization activity

0.61	GO:0005634	nucleus
0.55	GO:0030877	beta-catenin destruction complex
0.37	GO:0005829	cytosol
0.37	GO:0005769	early endosome
0.36	GO:0019005	SCF ubiquitin ligase complex
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.52

GO:0016874

tr|Q7ZVG7|Q7ZVG7_DANRE
Fgg protein
Search

FGG

0.97	Fibrinogen gamma polypeptide

0.82	GO:0007596	blood coagulation
0.77	GO:0001775	cell activation
0.74	GO:0051258	protein polymerization
0.59	GO:0007165	signal transduction
0.59	GO:0072376	protein activation cascade
0.56	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.56	GO:0042730	fibrinolysis
0.55	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.55	GO:0045907	positive regulation of vasoconstriction
0.55	GO:2000352	negative regulation of endothelial cell apoptotic process

0.77	GO:0030674	protein binding, bridging
0.70	GO:0005102	receptor binding
0.52	GO:0050839	cell adhesion molecule binding
0.44	GO:0005198	structural molecule activity
0.36	GO:0042803	protein homodimerization activity
0.35	GO:0046872	metal ion binding
0.32	GO:0008233	peptidase activity

0.84	GO:0005577	fibrinogen complex
0.55	GO:0031091	platelet alpha granule
0.52	GO:0009897	external side of plasma membrane
0.38	GO:0072562	blood microparticle
0.36	GO:0070062	extracellular exosome
0.35	GO:0005938	cell cortex
0.35	GO:0034774	secretory granule lumen
0.35	GO:0005788	endoplasmic reticulum lumen

0.32

GO:0008233

tr|Q7ZVG8|Q7ZVG8_DANRE
Serine/threonine kinase 25 (STE20 homolog, yeast)
Search

STK25

0.75	Serine/threonine-protein kinase 25

0.63	GO:0006468	protein phosphorylation
0.57	GO:0036481	intrinsic apoptotic signaling pathway in response to hydrogen peroxide
0.57	GO:0090168	Golgi reassembly
0.56	GO:0051683	establishment of Golgi localization
0.54	GO:0050772	positive regulation of axonogenesis
0.52	GO:0032874	positive regulation of stress-activated MAPK cascade
0.51	GO:0007163	establishment or maintenance of cell polarity
0.46	GO:0000185	activation of MAPKKK activity
0.45	GO:0009653	anatomical structure morphogenesis
0.45	GO:0031098	stress-activated protein kinase signaling cascade

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0042803	protein homodimerization activity
0.44	GO:0005057	signal transducer activity, downstream of receptor
0.34	GO:0046872	metal ion binding

0.49	GO:0005794	Golgi apparatus
0.37	GO:0031982	vesicle
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0016324	apical plasma membrane
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0031984	organelle subcompartment
0.36	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space
0.35	GO:0005829	cytosol

sp|Q7ZVH1|MPRGA_DANRE
Membrane progestin receptor gamma-A
Search

PAQR5

0.95	Membrane progestin receptor gamma-A

0.46	GO:0043401	steroid hormone mediated signaling pathway
0.39	GO:0048477	oogenesis
0.37	GO:0007275	multicellular organism development

0.48	GO:0005496	steroid binding
0.47	GO:0003707	steroid hormone receptor activity
0.33	GO:0005515	protein binding

0.39	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q7ZVH3|Q7ZVH3_DANRE
CDC23 (Cell division cycle 23, yeast, homolog)
Search

CDC23

0.92	Cell division cycle protein 23

0.77	GO:0030071	regulation of mitotic metaphase/anaphase transition
0.60	GO:0051301	cell division
0.59	GO:0070979	protein K11-linked ubiquitination
0.58	GO:0007080	mitotic metaphase plate congression
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.36	GO:0007091	metaphase/anaphase transition of mitotic cell cycle
0.35	GO:0007096	regulation of exit from mitosis
0.35	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.35	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process

0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0005515	protein binding
0.33	GO:0004872	receptor activity

0.76	GO:0005680	anaphase-promoting complex
0.34	GO:0005654	nucleoplasm
0.34	GO:0005829	cytosol

0.34

GO:0004842

tr|Q7ZVI2|Q7ZVI2_DANRE
Nuclear factor (Erythroid-derived 2)-like 2
Search

NFE2L2

0.97	Nuclear factor, erythroid 2 like 2

0.74	GO:0034599	cellular response to oxidative stress
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0006351	transcription, DNA-templated
0.53	GO:1903786	regulation of glutathione biosynthetic process
0.52	GO:0071499	cellular response to laminar fluid shear stress
0.52	GO:0036499	PERK-mediated unfolded protein response
0.52	GO:1902037	negative regulation of hematopoietic stem cell differentiation
0.52	GO:0051254	positive regulation of RNA metabolic process

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.53	GO:0001067	regulatory region nucleic acid binding
0.50	GO:0001102	RNA polymerase II activating transcription factor binding
0.47	GO:0019904	protein domain specific binding
0.46	GO:0046982	protein heterodimerization activity
0.38	GO:0001221	transcription cofactor binding
0.34	GO:0120013	intermembrane lipid transfer activity

0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.47	GO:0005813	centrosome
0.46	GO:0005667	transcription factor complex
0.45	GO:0000785	chromatin
0.45	GO:0032993	protein-DNA complex
0.43	GO:0012505	endomembrane system
0.43	GO:0070013	intracellular organelle lumen
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q7ZVI3|Q7ZVI3_DANRE
Ras homolog family member Q
Search

RHOQ

0.95	Epididymis secretory protein Li 42

0.77	GO:0007264	small GTPase mediated signal transduction
0.54	GO:0030036	actin cytoskeleton organization
0.53	GO:1903077	negative regulation of protein localization to plasma membrane
0.53	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis
0.52	GO:0061299	retina vasculature morphogenesis in camera-type eye
0.52	GO:0051491	positive regulation of filopodium assembly
0.52	GO:0046326	positive regulation of glucose import
0.51	GO:0008286	insulin receptor signaling pathway
0.51	GO:0008360	regulation of cell shape
0.51	GO:0030865	cortical cytoskeleton organization

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.55	GO:0032427	GBD domain binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0005522	profilin binding

0.50	GO:0005884	actin filament
0.50	GO:0045121	membrane raft
0.40	GO:0005886	plasma membrane
0.38	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.34	GO:0030660	Golgi-associated vesicle membrane

tr|Q7ZVI5|Q7ZVI5_DANRE
Pde6g protein
Search

PDE6G

0.97	Retinal rod rhodopsin-sensitive cgmp 3'5'-cyclic phosphodiesterase subunit gamma

0.77	GO:0007601	visual perception
0.52	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
0.52	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
0.50	GO:0000187	activation of MAPK activity
0.38	GO:0050896	response to stimulus
0.36	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.36	GO:0043086	negative regulation of catalytic activity
0.35	GO:0198738	cell-cell signaling by wnt

0.85	GO:0030553	cGMP binding
0.78	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.39	GO:0030507	spectrin binding
0.36	GO:0004857	enzyme inhibitor activity
0.33	GO:0008270	zinc ion binding

0.38	GO:0097381	photoreceptor disc membrane
0.36	GO:0042622	photoreceptor outer segment membrane

0.78

EC:3.1.4.17

GO:0004114

sp|Q7ZVI7|ACTB1_DANRE
Actin, cytoplasmic 1
Search

ACTB

0.55	Cytoskeletal beta-actin

0.49	GO:0030554	adenyl nucleotide binding
0.49	GO:0097367	carbohydrate derivative binding
0.49	GO:0008144	drug binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding

0.67	GO:0097433	dense body
0.63	GO:0005925	focal adhesion
0.55	GO:0005856	cytoskeleton
0.46	GO:0005886	plasma membrane
0.36	GO:0005634	nucleus

tr|Q7ZVI8|Q7ZVI8_DANRE
NPL4 homolog, ubiquitin recognition factor
Search

NPLOC4

0.93	NPL4 homolog, ubiquitin recognition factor

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.65	GO:0039536	negative regulation of RIG-I signaling pathway
0.64	GO:0032480	negative regulation of type I interferon production
0.62	GO:1903513	endoplasmic reticulum to cytosol transport
0.62	GO:0032527	protein exit from endoplasmic reticulum
0.59	GO:0036503	ERAD pathway

0.52	GO:0046872	metal ion binding
0.51	GO:0043130	ubiquitin binding
0.50	GO:0031625	ubiquitin protein ligase binding

0.66	GO:0036501	UFD1-NPL4 complex
0.63	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex
0.43	GO:0005634	nucleus

sp|Q7ZVJ6|QTRT2_DANRE
Queuine tRNA-ribosyltransferase accessory subunit 2
Search

QTRT2

0.79	Queuine tRNA-ribosyltransferase accessory subunit 2

0.70	GO:0101030	tRNA-guanine transglycosylation
0.45	GO:0008616	queuosine biosynthetic process

0.76	GO:0008479	queuine tRNA-ribosyltransferase activity
0.52	GO:0042803	protein homodimerization activity
0.51	GO:0046982	protein heterodimerization activity
0.50	GO:0046872	metal ion binding

0.69	GO:0005741	mitochondrial outer membrane
0.43	GO:0043234	protein complex

0.76

EC:2.4.2.29

GO:0008479

sp|Q7ZVJ8|CP13A_DANRE
UPF0585 protein C16orf13 homolog A
Search

METTL26

0.97	Methyltransferase like 26

0.60

GO:0032259

methylation

0.60

GO:0008168

methyltransferase activity

0.30

GO:0044425

membrane part

0.60

GO:0008168

tr|Q7ZVK2|Q7ZVK2_DANRE
Ubiquitin-conjugating enzyme E2G 1a (UBC7 homolog, yeast)
Search

UBE2G1

0.88	Ubiquitin-conjugating enzyme E2G 1

0.51	GO:0000209	protein polyubiquitination
0.47	GO:0044257	cellular protein catabolic process
0.44	GO:0043632	modification-dependent macromolecule catabolic process
0.40	GO:0006508	proteolysis

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0004842	ubiquitin-protein transferase activity
0.45	GO:0061659	ubiquitin-like protein ligase activity
0.44	GO:0061650	ubiquitin-like protein conjugating enzyme activity

0.36

GO:0005737

cytoplasm

0.47

GO:0004842

sp|Q7ZVK3|SIR2_DANRE
NAD-dependent protein deacetylase sirtuin-2
Search

SIRT2

0.64	NAD-dependent protein deacetylase

0.76	GO:0016575	histone deacetylation
0.57	GO:2000777	positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia
0.57	GO:0061433	cellular response to caloric restriction
0.56	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.56	GO:0090042	tubulin deacetylation
0.55	GO:1900195	positive regulation of oocyte maturation
0.55	GO:0034983	peptidyl-lysine deacetylation
0.55	GO:0071872	cellular response to epinephrine stimulus
0.55	GO:1900119	positive regulation of execution phase of apoptosis
0.55	GO:0048012	hepatocyte growth factor receptor signaling pathway

0.77	GO:0017136	NAD-dependent histone deacetylase activity
0.74	GO:0070403	NAD+ binding
0.60	GO:0008270	zinc ion binding
0.56	GO:0042903	tubulin deacetylase activity
0.56	GO:0034739	histone deacetylase activity (H4-K16 specific)
0.53	GO:0035035	histone acetyltransferase binding
0.51	GO:0042826	histone deacetylase binding
0.50	GO:0043130	ubiquitin binding
0.49	GO:0003682	chromatin binding
0.47	GO:0008134	transcription factor binding

0.55	GO:0033010	paranodal junction
0.55	GO:0043220	Schmidt-Lanterman incisure
0.53	GO:0072687	meiotic spindle
0.53	GO:0043204	perikaryon
0.52	GO:0030496	midbody
0.52	GO:0005814	centriole
0.51	GO:0072686	mitotic spindle
0.50	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005813	centrosome
0.48	GO:0005730	nucleolus

0.34

EC:2.4.2.30

GO:0003950

sp|Q7ZVK4|VPS36_DANRE
Vacuolar protein-sorting-associated protein 36
Search

VPS36

0.92	Vacuolar protein-sorting-associated protein 36

0.78	GO:0032509	endosome transport via multivesicular body sorting pathway
0.47	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
0.47	GO:0045324	late endosome to vacuole transport
0.47	GO:0072666	establishment of protein localization to vacuole
0.43	GO:0006886	intracellular protein transport
0.35	GO:0036258	multivesicular body assembly
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:2001141	regulation of RNA biosynthetic process
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression

0.79	GO:0032266	phosphatidylinositol-3-phosphate binding
0.78	GO:0043130	ubiquitin binding
0.54	GO:0008022	protein C-terminus binding
0.35	GO:0003730	mRNA 3'-UTR binding

0.79	GO:0000814	ESCRT II complex
0.56	GO:0031902	late endosome membrane
0.52	GO:0005764	lysosome
0.47	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.35	GO:0005634	nucleus

tr|Q7ZVK5|Q7ZVK5_DANRE
Pcbp2 protein
Search

PCBP2

0.87	Poly(RC)-binding protein 2 isoform c

0.59

GO:0003723

RNA binding

tr|Q7ZVK8|Q7ZVK8_DANRE
Mitogen-activated protein kinase
Search

0.57	Mitogen-activated protein kinase

0.79	GO:0000165	MAPK cascade
0.61	GO:0060440	trachea formation
0.61	GO:0042473	outer ear morphogenesis
0.61	GO:0061308	cardiac neural crest cell development involved in heart development
0.61	GO:0060020	Bergmann glial cell differentiation
0.60	GO:1903351	cellular response to dopamine
0.60	GO:1904355	positive regulation of telomere capping
0.59	GO:0070849	response to epidermal growth factor
0.59	GO:0030878	thyroid gland development
0.59	GO:0051973	positive regulation of telomerase activity

0.81	GO:0004707	MAP kinase activity
0.59	GO:0004708	MAP kinase kinase activity
0.58	GO:0001784	phosphotyrosine residue binding
0.56	GO:0019902	phosphatase binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0042802	identical protein binding
0.50	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity

0.60	GO:0031143	pseudopodium
0.51	GO:0005829	cytosol
0.50	GO:0005901	caveola
0.49	GO:0005925	focal adhesion
0.48	GO:0005770	late endosome
0.48	GO:0005769	early endosome
0.47	GO:0005634	nucleus
0.45	GO:0005794	Golgi apparatus
0.44	GO:0005856	cytoskeleton
0.44	GO:0005739	mitochondrion

0.81	EC:2.7.11.24	GO:0004707
0.81	KEGG:R00162	GO:0004707

sp|Q7ZVL2|WDR24_DANRE
WD repeat-containing protein 24
Search

WDR24

0.94	WD repeat-containing protein 24

0.80	GO:0032008	positive regulation of TOR signaling
0.52	GO:0034198	cellular response to amino acid starvation
0.47	GO:0010506	regulation of autophagy
0.39	GO:0006914	autophagy
0.33	GO:0016573	histone acetylation

0.33

GO:0004402

histone acetyltransferase activity

0.52	GO:0061700	GATOR2 complex
0.51	GO:0005765	lysosomal membrane

0.33

GO:0004402

tr|Q7ZVL5|Q7ZVL5_DANRE
Serine (Or cysteine) proteinase inhibitor, clade E (Nexin, plasminogen activator inhibitor type 1), member 2
Search

SERPINE2

0.94	Glia-derived nexin

0.58	GO:0061108	seminal vesicle epithelium development
0.58	GO:0042628	mating plug formation
0.57	GO:0010757	negative regulation of plasminogen activation
0.56	GO:0090331	negative regulation of platelet aggregation
0.56	GO:0021683	cerebellar granular layer morphogenesis
0.56	GO:0010766	negative regulation of sodium ion transport
0.56	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling
0.56	GO:0048505	regulation of timing of cell differentiation
0.56	GO:0048711	positive regulation of astrocyte differentiation
0.55	GO:0060384	innervation

0.53	GO:0004867	serine-type endopeptidase inhibitor activity
0.52	GO:0008201	heparin binding
0.48	GO:0005102	receptor binding
0.35	GO:0008233	peptidase activity
0.32	GO:0046872	metal ion binding

0.73	GO:0005615	extracellular space
0.56	GO:0031232	extrinsic component of external side of plasma membrane
0.55	GO:0031091	platelet alpha granule
0.53	GO:0031594	neuromuscular junction
0.49	GO:0031012	extracellular matrix
0.46	GO:0005829	cytosol
0.36	GO:1903561	extracellular vesicle
0.34	GO:0043025	neuronal cell body

0.35

GO:0008233

sp|Q7ZVM1|WASC5_DANRE
WASH complex subunit 5
Search

WASHC5

0.95	WASH complex subunit strumpellin

0.56	GO:0040038	polar body extrusion after meiotic divisions
0.55	GO:0090306	spindle assembly involved in meiosis
0.54	GO:0001556	oocyte maturation
0.50	GO:0016197	endosomal transport
0.37	GO:0048699	generation of neurons
0.37	GO:0015031	protein transport
0.37	GO:0031346	positive regulation of cell projection organization
0.36	GO:0010720	positive regulation of cell development
0.36	GO:0051962	positive regulation of nervous system development
0.36	GO:0120035	regulation of plasma membrane bounded cell projection organization

0.33	GO:0005515	protein binding
0.33	GO:0008270	zinc ion binding

0.80	GO:0071203	WASH complex
0.53	GO:0005769	early endosome
0.47	GO:0005654	nucleoplasm
0.36	GO:0043025	neuronal cell body
0.36	GO:0005783	endoplasmic reticulum
0.36	GO:0043005	neuron projection
0.36	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|Q7ZVM5|Q7ZVM5_DANRE
Tubulin gamma chain
Search

TUBG1

0.71	Tubulin gamma chain

0.84	GO:0031122	cytoplasmic microtubule organization
0.81	GO:0007020	microtubule nucleation
0.47	GO:0000212	meiotic spindle organization
0.35	GO:0007346	regulation of mitotic cell cycle
0.35	GO:1903047	mitotic cell cycle process
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0010564	regulation of cell cycle process
0.35	GO:0044839	cell cycle G2/M phase transition
0.34	GO:0051783	regulation of nuclear division

0.68	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0042802	identical protein binding
0.35	GO:0005200	structural constituent of cytoskeleton

0.84	GO:0000930	gamma-tubulin complex
0.73	GO:0005874	microtubule
0.54	GO:0000242	pericentriolar material
0.51	GO:0005819	spindle
0.47	GO:0055037	recycling endosome
0.46	GO:0036064	ciliary basal body
0.46	GO:0097730	non-motile cilium
0.46	GO:0005814	centriole
0.45	GO:0045177	apical part of cell
0.45	GO:0031252	cell leading edge

tr|Q7ZVM6|Q7ZVM6_DANRE
Cytotoxic granule-associated RNA binding protein 1, like
Search

TIA1

0.79	Cytotoxic granule-associated RNA binding protein transcript variant 1

0.51	GO:0017145	stem cell division
0.49	GO:0007281	germ cell development
0.48	GO:0008284	positive regulation of cell proliferation
0.42	GO:1903608	protein localization to cytoplasmic stress granule
0.41	GO:0042036	negative regulation of cytokine biosynthetic process
0.40	GO:0048024	regulation of mRNA splicing, via spliceosome
0.39	GO:0017148	negative regulation of translation
0.35	GO:0006915	apoptotic process
0.35	GO:1904037	positive regulation of epithelial cell apoptotic process
0.34	GO:0008543	fibroblast growth factor receptor signaling pathway

0.59	GO:0003723	RNA binding
0.47	GO:0003677	DNA binding
0.34	GO:0001965	G-protein alpha-subunit binding

0.51	GO:0010494	cytoplasmic stress granule
0.43	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.38	GO:0005829	cytosol
0.36	GO:0044446	intracellular organelle part
0.35	GO:0070062	extracellular exosome
0.34	GO:0005764	lysosome

sp|Q7ZVM9|RMI1_DANRE
RecQ-mediated genome instability protein 1
Search

RMI1

0.56	RecQ-mediated genome instability protein 1

0.40	GO:0006260	DNA replication
0.39	GO:0002023	reduction of food intake in response to dietary excess
0.37	GO:0035264	multicellular organism growth
0.37	GO:0009749	response to glucose
0.37	GO:0042593	glucose homeostasis
0.36	GO:0000732	strand displacement
0.35	GO:1901796	regulation of signal transduction by p53 class mediator
0.35	GO:0000731	DNA synthesis involved in DNA repair

0.52	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.33	GO:0005515	protein binding

0.55

GO:0016604

nuclear body

tr|Q7ZVN4|Q7ZVN4_DANRE
Palmitoyltransferase
Search

0.56	Palmitoyltransferase

0.52	GO:0018345	protein palmitoylation
0.39	GO:0034613	cellular protein localization
0.34	GO:0006506	GPI anchor biosynthetic process
0.34	GO:0097502	mannosylation
0.32	GO:0055114	oxidation-reduction process

0.80	GO:0019707	protein-cysteine S-acyltransferase activity
0.80	GO:0016409	palmitoyltransferase activity
0.34	GO:0000030	mannosyltransferase activity
0.32	GO:0016491	oxidoreductase activity

0.45	GO:0012505	endomembrane system
0.41	GO:0043231	intracellular membrane-bounded organelle
0.40	GO:0044444	cytoplasmic part
0.35	GO:0031501	mannosyltransferase complex
0.33	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:2.3.1

GO:0019707

tr|Q7ZVN5|Q7ZVN5_DANRE
Signal recognition particle 54 kDa protein
Search

SRP54

0.63	Signal recognition particle 54 kDa protein (Fragment)

0.75	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.47	GO:0042493	response to drug
0.35	GO:0065002	intracellular protein transmembrane transport
0.35	GO:0043623	cellular protein complex assembly

0.78	GO:0008312	7S RNA binding
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0030942	endoplasmic reticulum signal peptide binding
0.48	GO:0043021	ribonucleoprotein complex binding
0.40	GO:0008144	drug binding
0.33	GO:0005515	protein binding

0.80	GO:0005786	signal recognition particle, endoplasmic reticulum targeting
0.46	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0043232	intracellular non-membrane-bounded organelle

sp|Q7ZVN7|MED15_DANRE
Mediator of RNA polymerase II transcription subunit 15
Search

MED15

0.96	Mediator of RNA polymerase II transcription subunit 15

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.36	GO:0019827	stem cell population maintenance
0.33	GO:0000398	mRNA splicing, via spliceosome

0.79	GO:0001104	RNA polymerase II transcription cofactor activity
0.34	GO:0008013	beta-catenin binding

0.77	GO:0016592	mediator complex
0.34	GO:0005737	cytoplasm
0.33	GO:0005681	spliceosomal complex
0.30	GO:0016020	membrane

sp|Q7ZVP1|JADE3_DANRE
Protein Jade-3
Search

JADE3

0.97	PHD finger protein 16

0.58	GO:0043983	histone H4-K12 acetylation
0.57	GO:0043982	histone H4-K8 acetylation
0.57	GO:0043981	histone H4-K5 acetylation
0.55	GO:0043966	histone H3 acetylation
0.38	GO:0043984	histone H4-K16 acetylation
0.36	GO:0050790	regulation of catalytic activity
0.35	GO:0042051	compound eye photoreceptor development
0.35	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.33	GO:0034968	histone lysine methylation
0.32	GO:1903506	regulation of nucleic acid-templated transcription

0.53	GO:0046872	metal ion binding
0.37	GO:0030234	enzyme regulator activity
0.33	GO:0018024	histone-lysine N-methyltransferase activity
0.33	GO:0005515	protein binding
0.33	GO:0003676	nucleic acid binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0000123	histone acetyltransferase complex
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.1.1.43

GO:0018024

tr|Q7ZVP2|Q7ZVP2_DANRE
RAB5C, member RAS oncogene family
Search

RAB5C

0.95	RAB5C, member RAS oncogene family

0.69	GO:0048227	plasma membrane to endosome transport
0.61	GO:0030100	regulation of endocytosis
0.53	GO:0007032	endosome organization
0.49	GO:0019882	antigen processing and presentation
0.45	GO:0001702	gastrulation with mouth forming second
0.44	GO:0001525	angiogenesis
0.43	GO:0098609	cell-cell adhesion
0.35	GO:0006897	endocytosis

0.68	GO:0003924	GTPase activity
0.66	GO:0019003	GDP binding
0.66	GO:0005525	GTP binding
0.54	GO:0030742	GTP-dependent protein binding

0.64	GO:0005768	endosome
0.58	GO:0030139	endocytic vesicle
0.56	GO:0005811	lipid droplet
0.52	GO:0070062	extracellular exosome
0.45	GO:0098993	anchored component of synaptic vesicle membrane
0.42	GO:0005886	plasma membrane
0.41	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0001726	ruffle
0.36	GO:0045121	membrane raft
0.35	GO:0015629	actin cytoskeleton

sp|Q7ZVP8|TM38B_DANRE
Trimeric intracellular cation channel type B
Search

TMEM38B

0.90	Transmembrane protein 38B

0.62	GO:0015672	monovalent inorganic cation transport
0.61	GO:0098655	cation transmembrane transport
0.45	GO:0030001	metal ion transport
0.43	GO:0098660	inorganic ion transmembrane transport
0.30	GO:0009987	cellular process

0.74	GO:0005261	cation channel activity
0.48	GO:0015079	potassium ion transmembrane transporter activity
0.48	GO:0022839	ion gated channel activity
0.47	GO:0008381	mechanosensitive ion channel activity

0.30

GO:0016021

integral component of membrane

sp|Q7ZVQ8|NS1BB_DANRE
Influenza virus NS1A-binding protein homolog B
Search

IVNS1ABP

0.94	Influenza virus NS1A binding protein IV

0.55	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.34	GO:0006383	transcription by RNA polymerase III
0.34	GO:0009615	response to virus
0.34	GO:0008380	RNA splicing
0.33	GO:0016032	viral process

0.33

GO:0005515

protein binding

0.74	GO:0015629	actin cytoskeleton
0.47	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0044446	intracellular organelle part

sp|Q7ZVR1|WDR75_DANRE
WD repeat-containing protein 75
Search

WDR75

0.92	WD repeat-containing protein 75

0.80	GO:2000234	positive regulation of rRNA processing
0.77	GO:1903146	regulation of autophagy of mitochondrion
0.77	GO:0045943	positive regulation of transcription by RNA polymerase I
0.76	GO:1903955	positive regulation of protein targeting to mitochondrion
0.42	GO:0006364	rRNA processing
0.39	GO:0006351	transcription, DNA-templated

0.40	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0003723	RNA binding
0.30	GO:0003824	catalytic activity

0.67	GO:0005730	nucleolus
0.36	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q7ZVR6|MYNN_DANRE
Myoneurin
Search

MYNN

0.56

Myoneurin

0.56	GO:1990823	response to leukemia inhibitory factor
0.53	GO:0071345	cellular response to cytokine stimulus
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:0010468	regulation of gene expression
0.35	GO:0097659	nucleic acid-templated transcription
0.35	GO:0010467	gene expression
0.34	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.35	GO:0046872	metal ion binding
0.33	GO:0003700	DNA binding transcription factor activity

0.45

GO:0005634

nucleus

sp|Q7ZVR8|ESRP2_DANRE
Epithelial splicing regulatory protein 2
Search

ESRP2

0.90	LOW QUALITY PROTEIN: epithelial splicing regulatory protein 2

0.72	GO:0043484	regulation of RNA splicing
0.44	GO:0060445	branching involved in salivary gland morphogenesis
0.44	GO:0060441	epithelial tube branching involved in lung morphogenesis
0.44	GO:0000380	alternative mRNA splicing, via spliceosome
0.43	GO:0050679	positive regulation of epithelial cell proliferation
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0008543	fibroblast growth factor receptor signaling pathway

0.54	GO:0003723	RNA binding
0.34	GO:0004930	G-protein coupled receptor activity
0.32	GO:0005515	protein binding

0.44	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

sp|Q7ZVS3|PLK4_DANRE
Serine/threonine-protein kinase PLK4
Search

PLK4

0.74	Serine/threonine-protein kinase PLK4

0.85	GO:0007099	centriole replication
0.63	GO:0006468	protein phosphorylation
0.60	GO:0046601	positive regulation of centriole replication
0.58	GO:0098535	de novo centriole assembly involved in multi-ciliated epithelial cell differentiation
0.52	GO:0060707	trophoblast giant cell differentiation
0.42	GO:0060271	cilium assembly
0.41	GO:0048589	developmental growth
0.37	GO:0000086	G2/M transition of mitotic cell cycle
0.36	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.36	GO:0140056	organelle localization by membrane tethering

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0042802	identical protein binding
0.34	GO:0003735	structural constituent of ribosome

0.83	GO:0005814	centriole
0.57	GO:0098536	deuterosome
0.50	GO:0001741	XY body
0.50	GO:0005730	nucleolus
0.46	GO:0005813	centrosome
0.43	GO:0005829	cytosol
0.41	GO:0032154	cleavage furrow
0.34	GO:0005840	ribosome

0.70

GO:0004674

tr|Q7ZVS6|Q7ZVS6_DANRE
GATS protein-like 2
Search

GATSL2

0.96	Cytosolic arginine sensor for mTORC1 subunit 2

0.83	GO:1903432	regulation of TORC1 signaling
0.70	GO:0032007	negative regulation of TOR signaling
0.61	GO:1903577	cellular response to L-arginine
0.37	GO:0010469	regulation of receptor activity
0.37	GO:0006955	immune response
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.61	GO:0042802	identical protein binding
0.57	GO:0034618	arginine binding
0.38	GO:0005125	cytokine activity
0.34	GO:0003677	DNA binding

0.72	GO:0061700	GATOR2 complex
0.58	GO:0005829	cytosol
0.36	GO:0005576	extracellular region
0.35	GO:0005634	nucleus

sp|Q7ZVS8|CMTR2_DANRE
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2
Search

CMTR2

0.97	FtsJ methyltransferase domain-containing protein 1

0.63	GO:0032259	methylation
0.52	GO:0016556	mRNA modification
0.50	GO:0006370	7-methylguanosine mRNA capping
0.38	GO:0044260	cellular macromolecule metabolic process
0.37	GO:0007424	open tracheal system development
0.33	GO:0035239	tube morphogenesis
0.33	GO:0016477	cell migration
0.32	GO:0010466	negative regulation of peptidase activity
0.32	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.32	GO:0043038	amino acid activation

0.63	GO:0008168	methyltransferase activity
0.44	GO:0140098	catalytic activity, acting on RNA
0.32	GO:0030414	peptidase inhibitor activity
0.32	GO:0052689	carboxylic ester hydrolase activity
0.32	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.31	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.63	EC:2.1.1	GO:0008168
0.32	KEGG:R00630	GO:0052689

sp|Q7ZVS9|MYCB_DANRE
Transcriptional regulator Myc-B
Search

C-MYC

0.93	Transcriptional regulator Myc-B

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.42	GO:0045656	negative regulation of monocyte differentiation
0.42	GO:0048146	positive regulation of fibroblast proliferation
0.41	GO:0010332	response to gamma radiation
0.41	GO:2001022	positive regulation of response to DNA damage stimulus
0.41	GO:0032204	regulation of telomere maintenance
0.41	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.41	GO:0050679	positive regulation of epithelial cell proliferation

0.65	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.42	GO:0070888	E-box binding
0.39	GO:0032403	protein complex binding
0.34	GO:0005198	structural molecule activity
0.33	GO:0019902	phosphatase binding

0.60	GO:0005634	nucleus
0.40	GO:0031974	membrane-enclosed lumen
0.40	GO:0042025	host cell nucleus
0.39	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0044446	intracellular organelle part
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0019028	viral capsid

tr|Q7ZVT1|Q7ZVT1_DANRE
Increased sodium tolerance 1 homolog (yeast)
Search

IST1

0.96	Increased sodium tolerance 1 homolog

0.70	GO:0048675	axon extension
0.69	GO:0007032	endosome organization
0.65	GO:0015031	protein transport

sp|Q7ZVT3|SAS6_DANRE
Spindle assembly abnormal protein 6 homolog
Search

SASS6

0.88	Spindle assembly abnormal protein 6

0.85	GO:0007099	centriole replication
0.46	GO:0040016	embryonic cleavage
0.44	GO:0007052	mitotic spindle organization
0.43	GO:0007283	spermatogenesis
0.42	GO:0000280	nuclear division
0.33	GO:0006836	neurotransmitter transport
0.32	GO:0065009	regulation of molecular function
0.32	GO:0055085	transmembrane transport

0.35	GO:0005515	protein binding
0.33	GO:0005328	neurotransmitter:sodium symporter activity
0.33	GO:0098772	molecular function regulator

0.85	GO:0098536	deuterosome
0.83	GO:0005814	centriole
0.76	GO:0005813	centrosome
0.65	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q7ZVT5|ROGDI_DANRE
Protein rogdi homolog
Search

ROGDI

0.95	Glyoxylate reductase 1 homolog (Arabidopsis)

0.80	GO:0042475	odontogenesis of dentin-containing tooth
0.77	GO:0007420	brain development
0.74	GO:0030097	hemopoiesis
0.74	GO:0008284	positive regulation of cell proliferation
0.73	GO:0022008	neurogenesis
0.36	GO:0055114	oxidation-reduction process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.41	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity
0.39	GO:0051287	NAD binding
0.33	GO:0043565	sequence-specific DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.74	GO:0005635	nuclear envelope
0.30	GO:0031224	intrinsic component of membrane

0.41

EC:1.1.1.44

GO:0004616

sp|Q7ZVU1|GARE1_DANRE
GRB2-associated and regulator of MAPK protein 1
Search

GAREM1

0.94	GRB2 associated regulator of MAPK1 subtype 1

0.86	GO:0071364	cellular response to epidermal growth factor stimulus
0.85	GO:0007173	epidermal growth factor receptor signaling pathway
0.84	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.79	GO:0008284	positive regulation of cell proliferation

0.86

GO:0070064

proline-rich region binding

tr|Q7ZVU7|Q7ZVU7_DANRE
S-adenosylmethionine decarboxylase proenzyme
Search

AMD1

0.56	S-adenosylmethionine decarboxylase proenzyme

0.83	GO:0006597	spermine biosynthetic process
0.76	GO:0008295	spermidine biosynthetic process
0.68	GO:0006557	S-adenosylmethioninamine biosynthetic process
0.36	GO:0001701	in utero embryonic development
0.34	GO:0046500	S-adenosylmethionine metabolic process

0.79	GO:0004014	adenosylmethionine decarboxylase activity
0.47	GO:0019810	putrescine binding
0.33	GO:0005515	protein binding

0.42

GO:0005829

cytosol

0.79	EC:4.1.1.50	GO:0004014
0.79	KEGG:R00178	GO:0004014

sp|Q7ZVV1|ERCC3_DANRE
TFIIH basal transcription factor complex helicase XPB subunit
Search

ERCC3

0.86	General transcription and DNA repair factor IIH helicase subunit XPB

0.76	GO:0006367	transcription initiation from RNA polymerase II promoter
0.70	GO:0006289	nucleotide-excision repair
0.67	GO:0032392	DNA geometric change
0.59	GO:0009650	UV protection
0.58	GO:0035315	hair cell differentiation
0.54	GO:0006915	apoptotic process
0.54	GO:1901990	regulation of mitotic cell cycle phase transition
0.54	GO:0043065	positive regulation of apoptotic process
0.53	GO:0045944	positive regulation of transcription by RNA polymerase II
0.52	GO:0006265	DNA topological change

0.69	GO:0004003	ATP-dependent DNA helicase activity
0.58	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.58	GO:0047485	protein N-terminus binding
0.57	GO:0008022	protein C-terminus binding
0.55	GO:0043138	3'-5' DNA helicase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0003677	DNA binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0008134	transcription factor binding

0.57	GO:0005675	holo TFIIH complex
0.54	GO:0005669	transcription factor TFIID complex
0.38	GO:0000439	core TFIIH complex
0.34	GO:0005576	extracellular region
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.58

EC:2.7.11.23

GO:0008353

tr|Q7ZVV4|Q7ZVV4_DANRE
General transcription factor IIH, polypeptide 2
Search

GTF2H2

0.93	General transcription factor IIH polypeptide 2

0.73	GO:0006289	nucleotide-excision repair
0.58	GO:0006351	transcription, DNA-templated
0.45	GO:0006357	regulation of transcription by RNA polymerase II
0.37	GO:0002031	G-protein coupled receptor internalization
0.36	GO:0006468	protein phosphorylation
0.35	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.35	GO:0006359	regulation of transcription by RNA polymerase III
0.35	GO:0009411	response to UV
0.35	GO:0006915	apoptotic process
0.34	GO:0043604	amide biosynthetic process

0.61	GO:0008270	zinc ion binding
0.49	GO:0003676	nucleic acid binding
0.39	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.37	GO:0047485	protein N-terminus binding
0.37	GO:0008094	DNA-dependent ATPase activity
0.35	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.35	GO:0001026	TFIIIB-type transcription factor activity
0.34	GO:0004146	dihydrofolate reductase activity
0.33	GO:0016874	ligase activity
0.33	GO:0003700	DNA binding transcription factor activity

0.81	GO:0000439	core TFIIH complex
0.51	GO:0005675	holo TFIIH complex
0.37	GO:0016607	nuclear speck
0.36	GO:0005669	transcription factor TFIID complex
0.35	GO:0000126	transcription factor TFIIIB complex
0.30	GO:0016020	membrane

0.39

EC:2.7.11.23

GO:0008353

tr|Q7ZVV6|Q7ZVV6_DANRE
Slc25a14 protein
Search

SLC25A14

0.93	Brain mitochondrial carrier protein short-inserted form

0.77	GO:0006839	mitochondrial transport
0.40	GO:0055085	transmembrane transport
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0009060	aerobic respiration
0.33	GO:0015992	proton transport

0.39	GO:0022857	transmembrane transporter activity
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005515	protein binding

0.62	GO:0031966	mitochondrial membrane
0.58	GO:0019866	organelle inner membrane
0.33	GO:0005887	integral component of plasma membrane

sp|Q7ZVW1|TM117_DANRE
Transmembrane protein 117
Search

TMEM117

0.97	Transmembrane protein 117

0.58

GO:0070059

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

0.49	GO:0005783	endoplasmic reticulum
0.43	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q7ZVW8|Q7ZVW8_DANRE
CWC25 spliceosome-associated protein homolog (S. cerevisiae)
Search

CWC25

0.88	Coiled-coil domain-containing protein 49

0.39	GO:0000226	microtubule cytoskeleton organization
0.38	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0046854	phosphatidylinositol phosphorylation

0.35	GO:0016307	phosphatidylinositol phosphate kinase activity
0.33	GO:0016787	hydrolase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.78	GO:0016607	nuclear speck
0.38	GO:0015630	microtubule cytoskeleton
0.30	GO:0016020	membrane

0.35

GO:0016307

sp|Q7ZVW9|ARGLB_DANRE
Arginine and glutamate-rich protein 1-B
Search

ARGLU1

0.97	LOW QUALITY PROTEIN: arginine and glutamate-rich protein 1

0.36	GO:0036211	protein modification process
0.35	GO:0044267	cellular protein metabolic process
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.35	GO:0048013	ephrin receptor signaling pathway

0.77	GO:0045296	cadherin binding
0.35	GO:0046875	ephrin receptor binding

0.67	GO:0005654	nucleoplasm
0.59	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

sp|Q7ZVX0|CCNL1_DANRE
Cyclin-L1
Search

0.78	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
0.61	GO:0006396	RNA processing
0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.49	GO:1904031	positive regulation of cyclin-dependent protein kinase activity
0.48	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.48	GO:0045787	positive regulation of cell cycle
0.45	GO:0051254	positive regulation of RNA metabolic process
0.45	GO:0010557	positive regulation of macromolecule biosynthetic process

0.49	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.36	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.60	GO:0005634	nucleus
0.49	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.41	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part
0.33	GO:0044444	cytoplasmic part
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle

0.49

GO:0016538

tr|Q7ZVX4|Q7ZVX4_DANRE
RAB14, member RAS oncogene family
Search

RAB14

0.94	RAB14, member RAS oncogene family, like

0.85	GO:0090382	phagosome maturation
0.85	GO:0006895	Golgi to endosome transport
0.84	GO:0032456	endocytic recycling
0.78	GO:0042742	defense response to bacterium
0.65	GO:0008543	fibroblast growth factor receptor signaling pathway
0.60	GO:0009790	embryo development
0.60	GO:0032879	regulation of localization
0.45	GO:0051128	regulation of cellular component organization

0.69	GO:0031489	myosin V binding
0.68	GO:0003924	GTPase activity
0.66	GO:0019003	GDP binding
0.66	GO:0005525	GTP binding

0.83	GO:0045335	phagocytic vesicle
0.83	GO:0055037	recycling endosome
0.79	GO:0005802	trans-Golgi network
0.68	GO:0005829	cytosol

sp|Q7ZVX5|REEP3_DANRE
Receptor expression-enhancing protein 3
Search

REEP3

0.71	Receptor expression-enhancing protein 3-A

0.57	GO:0007084	mitotic nuclear envelope reassembly
0.38	GO:0051301	cell division

0.35

GO:0008017

microtubule binding

0.41	GO:0005783	endoplasmic reticulum
0.40	GO:0005874	microtubule
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.30	GO:0044425	membrane part

sp|Q7ZVX6|UBA3_DANRE
NEDD8-activating enzyme E1 catalytic subunit
Search

UBA3

0.91	Ubiquitin like modifier activating enzyme 3

0.84	GO:0045116	protein neddylation
0.64	GO:0007113	endomitotic cell cycle
0.53	GO:0051726	regulation of cell cycle

0.84	GO:0019781	NEDD8 activating enzyme activity
0.71	GO:0016881	acid-amino acid ligase activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0046982	protein heterodimerization activity
0.54	GO:0042802	identical protein binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm

0.71

EC:6.3.2

GO:0016881

tr|Q7ZVX7|Q7ZVX7_DANRE
Activating transcription factor 3
Search

ATF3

0.97	cyclic AMP-dependent transcription factor ATF-3

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.60	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway
0.57	GO:0035914	skeletal muscle cell differentiation
0.57	GO:0034198	cellular response to amino acid starvation
0.57	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.56	GO:0030968	endoplasmic reticulum unfolded protein response
0.56	GO:0043620	regulation of DNA-templated transcription in response to stress
0.51	GO:0045892	negative regulation of transcription, DNA-templated
0.51	GO:0010604	positive regulation of macromolecule metabolic process
0.51	GO:0051173	positive regulation of nitrogen compound metabolic process

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0042803	protein homodimerization activity
0.51	GO:0046982	protein heterodimerization activity
0.38	GO:0003682	chromatin binding
0.34	GO:0003714	transcription corepressor activity

0.61	GO:1990622	CHOP-ATF3 complex
0.60	GO:0005634	nucleus
0.48	GO:0043233	organelle lumen
0.44	GO:0043232	intracellular non-membrane-bounded organelle
0.43	GO:0044446	intracellular organelle part
0.34	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

tr|Q7ZVX8|Q7ZVX8_DANRE
ATPase, H+ transporting, V1 subunit D
Search

ATP6V1D

0.83	Vacuolar ATP synthase subunit D

0.55	GO:0055085	transmembrane transport
0.53	GO:0061512	protein localization to cilium
0.50	GO:0060271	cilium assembly
0.36	GO:0015992	proton transport
0.35	GO:0090383	phagosome acidification
0.35	GO:0033572	transferrin transport
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0008286	insulin receptor signaling pathway
0.34	GO:0016241	regulation of macroautophagy
0.34	GO:0042998	positive regulation of Golgi to plasma membrane protein transport

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.35	GO:0005515	protein binding
0.33	GO:0022853	active ion transmembrane transporter activity
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.50	GO:0005813	centrosome
0.49	GO:0005929	cilium
0.49	GO:0033176	proton-transporting V-type ATPase complex
0.39	GO:0005765	lysosomal membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0035579	specific granule membrane
0.34	GO:0005802	trans-Golgi network
0.33	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q7ZVX9|Q7ZVX9_DANRE
Thioredoxin domain containing 9
Search

TXNDC9

0.92	ATP binding protein associated with cell differentiation

0.67	GO:0045454	cell redox homeostasis
0.44	GO:0008616	queuosine biosynthetic process
0.33	GO:0016998	cell wall macromolecule catabolic process
0.33	GO:0009253	peptidoglycan catabolic process

0.51	GO:0045296	cadherin binding
0.46	GO:0008479	queuine tRNA-ribosyltransferase activity
0.33	GO:0003796	lysozyme activity

0.52	GO:0030496	midbody
0.49	GO:0005813	centrosome
0.46	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.46

EC:2.4.2.29

GO:0008479

tr|Q7ZVY0|Q7ZVY0_DANRE
Cytotoxic granule-associated RNA binding protein 1
Search

TIA1

0.86	Cytotoxic granule-associated RNA binding protein transcript variant 1

0.54	GO:1903608	protein localization to cytoplasmic stress granule
0.53	GO:0042036	negative regulation of cytokine biosynthetic process
0.51	GO:0048024	regulation of mRNA splicing, via spliceosome
0.48	GO:0017148	negative regulation of translation
0.39	GO:1904037	positive regulation of epithelial cell apoptotic process
0.35	GO:0006915	apoptotic process
0.34	GO:0008543	fibroblast growth factor receptor signaling pathway

0.59	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.54	GO:0097165	nuclear stress granule
0.50	GO:0010494	cytoplasmic stress granule
0.46	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|Q7ZVY3|Q7ZVY3_DANRE
Nfyc protein
Search

NFYC

0.78	Nuclear transcription factor Y subunit gamma

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0060041	retina development in camera-type eye
0.40	GO:0051254	positive regulation of RNA metabolic process
0.40	GO:0010557	positive regulation of macromolecule biosynthetic process
0.40	GO:0031328	positive regulation of cellular biosynthetic process
0.33	GO:0045540	regulation of cholesterol biosynthetic process
0.32	GO:0006457	protein folding

0.74	GO:0046982	protein heterodimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.42	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0008134	transcription factor binding
0.33	GO:0003713	transcription coactivator activity

0.84	GO:0016602	CCAAT-binding factor complex
0.41	GO:0032993	protein-DNA complex
0.41	GO:0005654	nucleoplasm

sp|Q7ZVY5|CISY_DANRE
Citrate synthase, mitochondrial
Search

0.45	Citrate synthase, mitochondrial

0.70	GO:0006101	citrate metabolic process
0.63	GO:0009060	aerobic respiration
0.44	GO:0005975	carbohydrate metabolic process
0.35	GO:0014823	response to activity
0.34	GO:0006107	oxaloacetate metabolic process
0.34	GO:0006084	acetyl-CoA metabolic process

0.76	GO:0004108	citrate (Si)-synthase activity
0.34	GO:0003723	RNA binding

0.52	GO:0005759	mitochondrial matrix
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus

0.76

EC:2.3.3.1

GO:0004108

tr|Q7ZVZ1|Q7ZVZ1_DANRE
F-box and WD repeat domain-containing 11a
Search

FBXW11

0.96	F-box and WD repeat domain containing 11

0.52	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.52	GO:0042347	negative regulation of NF-kappaB import into nucleus
0.51	GO:0042753	positive regulation of circadian rhythm
0.51	GO:0031648	protein destabilization
0.49	GO:0000209	protein polyubiquitination
0.48	GO:0045862	positive regulation of proteolysis
0.46	GO:0045893	positive regulation of transcription, DNA-templated
0.45	GO:0006470	protein dephosphorylation
0.45	GO:0045892	negative regulation of transcription, DNA-templated
0.40	GO:0002040	sprouting angiogenesis

0.66	GO:0046983	protein dimerization activity
0.47	GO:0061630	ubiquitin protein ligase activity

0.50	GO:0019005	SCF ubiquitin ligase complex
0.48	GO:0005813	centrosome
0.44	GO:0005829	cytosol
0.42	GO:0005634	nucleus

sp|Q7ZVZ6|PREP_DANRE
Presequence protease, mitochondrial
Search

PITRM1

0.97	Pitrilysin metalloproteinase 1

0.60

GO:0006508

proteolysis

0.56	GO:0004222	metalloendopeptidase activity
0.54	GO:0046872	metal ion binding

0.59	GO:0005759	mitochondrial matrix
0.30	GO:0044425	membrane part

0.56

GO:0004222

sp|Q7ZVZ7|AB17C_DANRE
Protein ABHD17C
Search

0.37	Alpha/beta hydrolase

0.55	GO:0098734	macromolecule depalmitoylation
0.53	GO:0018345	protein palmitoylation
0.53	GO:1902816	regulation of protein localization to microtubule
0.52	GO:1905668	positive regulation of protein localization to endosome
0.50	GO:0042159	lipoprotein catabolic process
0.49	GO:1903828	negative regulation of cellular protein localization
0.47	GO:0035601	protein deacylation
0.38	GO:0072657	protein localization to membrane
0.34	GO:0006508	proteolysis

0.55	GO:0008474	palmitoyl-(protein) hydrolase activity
0.35	GO:0017171	serine hydrolase activity
0.34	GO:0070011	peptidase activity, acting on L-amino acid peptides

0.49	GO:0014069	postsynaptic density
0.39	GO:0010008	endosome membrane
0.35	GO:0005886	plasma membrane

0.55

EC:3.1.2.22

GO:0008474

sp|Q7ZW00|AGK_DANRE
Acylglycerol kinase, mitochondrial
Search

AGK

0.97	Acylglycerol kinase, mitochondrial

0.57	GO:0016310	phosphorylation
0.57	GO:0045039	protein import into mitochondrial inner membrane
0.55	GO:0046513	ceramide biosynthetic process
0.49	GO:0030258	lipid modification
0.38	GO:0046486	glycerolipid metabolic process
0.33	GO:0008654	phospholipid biosynthetic process

0.76	GO:0003951	NAD+ kinase activity
0.58	GO:0001729	ceramide kinase activity
0.43	GO:0047620	acylglycerol kinase activity
0.40	GO:0004143	diacylglycerol kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0042721	mitochondrial inner membrane protein insertion complex
0.55	GO:0031305	integral component of mitochondrial inner membrane
0.54	GO:0005758	mitochondrial intermembrane space
0.34	GO:0005741	mitochondrial outer membrane
0.33	GO:0005829	cytosol

0.76	EC:2.7.1.23	GO:0003951
0.76	KEGG:R00104	GO:0003951

sp|Q7ZW02|CHPT1_DANRE
Cholinephosphotransferase 1
Search

0.89	Choline/ethanolamine phosphotransferase 1

0.68	GO:0008654	phospholipid biosynthetic process
0.58	GO:0046470	phosphatidylcholine metabolic process
0.53	GO:0045017	glycerolipid biosynthetic process
0.53	GO:0046469	platelet activating factor metabolic process
0.43	GO:1901566	organonitrogen compound biosynthetic process
0.38	GO:0046337	phosphatidylethanolamine metabolic process
0.34	GO:0001558	regulation of cell growth
0.34	GO:0010469	regulation of receptor activity

0.72	GO:0016780	phosphotransferase activity, for other substituted phosphate groups
0.36	GO:0046872	metal ion binding
0.35	GO:0019992	diacylglycerol binding
0.34	GO:0005179	hormone activity

0.46	GO:0031984	organelle subcompartment
0.46	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.46	GO:0044432	endoplasmic reticulum part
0.38	GO:0044431	Golgi apparatus part
0.38	GO:0098588	bounding membrane of organelle
0.38	GO:0031965	nuclear membrane
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.72

EC:2.7.8

GO:0016780

tr|Q7ZW04|Q7ZW04_DANRE
S-adenosylmethionine synthase
Search

MAT1A

0.54	S-adenosylmethionine synthase

0.79	GO:0006556	S-adenosylmethionine biosynthetic process
0.72	GO:0006730	one-carbon metabolic process
0.54	GO:0009087	methionine catabolic process
0.53	GO:0034214	protein hexamerization
0.52	GO:0051291	protein heterooligomerization
0.50	GO:1990830	cellular response to leukemia inhibitory factor
0.50	GO:0051289	protein homotetramerization
0.36	GO:0055013	cardiac muscle cell development
0.35	GO:0072358	cardiovascular system development
0.34	GO:0051591	response to cAMP

0.79	GO:0004478	methionine adenosyltransferase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0046872	metal ion binding
0.53	GO:0042802	identical protein binding
0.35	GO:0016597	amino acid binding
0.33	GO:0046983	protein dimerization activity

0.56	GO:0048269	methionine adenosyltransferase complex
0.45	GO:0005829	cytosol
0.34	GO:0016363	nuclear matrix

0.79

EC:2.5.1.6

GO:0004478

tr|Q7ZW09|Q7ZW09_DANRE
Heterogeneous nuclear ribonucleoprotein L
Search

HNRNPL

0.82	Heterogeneous nuclear ribonucleoprotein L

0.68	GO:0006397	mRNA processing
0.49	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.35	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
0.34	GO:1902416	positive regulation of mRNA binding
0.34	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.34	GO:0034198	cellular response to amino acid starvation
0.34	GO:0007623	circadian rhythm
0.34	GO:1901652	response to peptide
0.34	GO:0045727	positive regulation of translation

0.58	GO:0003723	RNA binding
0.41	GO:0044212	transcription regulatory region DNA binding
0.35	GO:0005515	protein binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.30	GO:0003824	catalytic activity

0.62	GO:0019013	viral nucleocapsid
0.60	GO:0005634	nucleus
0.55	GO:0030529	intracellular ribonucleoprotein complex
0.40	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0070062	extracellular exosome
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q7ZW11|TM39B_DANRE
Transmembrane protein 39B
Search

TMEM39B

0.97	Transmembrane protein 39B

0.35

GO:0003723

RNA binding

0.30

GO:0044425

membrane part

tr|Q7ZW12|Q7ZW12_DANRE
ABI family, member 3 (NESH)-binding protein b
Search

0.75	ABI family, member 3 (NESH)-binding protein b

tr|Q7ZW13|Q7ZW13_DANRE
Transportin 3
Search

TNPO3

0.90	Transportin-3 protein 1

0.57	GO:0035048	splicing factor protein import into nucleus
0.49	GO:0006886	intracellular protein transport
0.46	GO:0030217	T cell differentiation
0.43	GO:0008380	RNA splicing
0.42	GO:0006397	mRNA processing

0.54	GO:0008536	Ran GTPase binding
0.48	GO:0008139	nuclear localization sequence binding
0.48	GO:0042802	identical protein binding
0.43	GO:0008565	protein transporter activity
0.33	GO:0004872	receptor activity

0.60	GO:0005634	nucleus
0.42	GO:0012505	endomembrane system
0.40	GO:0031967	organelle envelope
0.40	GO:0031090	organelle membrane
0.36	GO:0005737	cytoplasm

sp|Q7ZW16|RNF41_DANRE
E3 ubiquitin-protein ligase NRDP1
Search

RNF41

0.93	E3 ubiquitin protein ligase neuregulin receptor degradation protein-1

0.72	GO:0016567	protein ubiquitination
0.56	GO:1901525	negative regulation of mitophagy
0.55	GO:0097191	extrinsic apoptotic signaling pathway
0.54	GO:2000379	positive regulation of reactive oxygen species metabolic process
0.54	GO:0051896	regulation of protein kinase B signaling
0.53	GO:0030336	negative regulation of cell migration
0.53	GO:0045619	regulation of lymphocyte differentiation
0.52	GO:0045637	regulation of myeloid cell differentiation
0.52	GO:0051091	positive regulation of DNA binding transcription factor activity
0.52	GO:0045732	positive regulation of protein catabolic process

0.76	GO:0061630	ubiquitin protein ligase activity
0.57	GO:0005135	interleukin-3 receptor binding
0.56	GO:0005128	erythropoietin receptor binding
0.56	GO:0017160	Ral GTPase binding
0.55	GO:0008270	zinc ion binding
0.54	GO:0030971	receptor tyrosine kinase binding
0.51	GO:0016874	ligase activity
0.50	GO:0019904	protein domain specific binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0003677	DNA binding

0.55	GO:0071782	endoplasmic reticulum tubular network
0.52	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0071565	nBAF complex
0.36	GO:0071564	npBAF complex
0.36	GO:0016514	SWI/SNF complex
0.34	GO:0005829	cytosol

0.51

GO:0016874

tr|Q7ZW20|Q7ZW20_DANRE
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1
Search

YWHAE

0.89	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon

0.56	GO:1905912	regulation of calcium ion export across plasma membrane
0.55	GO:1902309	negative regulation of peptidyl-serine dephosphorylation
0.52	GO:0046827	positive regulation of protein export from nucleus
0.52	GO:0060306	regulation of membrane repolarization
0.52	GO:1901020	negative regulation of calcium ion transmembrane transporter activity
0.52	GO:1901016	regulation of potassium ion transmembrane transporter activity
0.50	GO:0034605	cellular response to heat
0.50	GO:0051480	regulation of cytosolic calcium ion concentration
0.50	GO:0021766	hippocampus development
0.50	GO:0000165	MAPK cascade

0.76	GO:0019904	protein domain specific binding
0.53	GO:0050815	phosphoserine residue binding
0.52	GO:0015459	potassium channel regulator activity
0.52	GO:0097110	scaffold protein binding
0.52	GO:0005246	calcium channel regulator activity
0.51	GO:0044325	ion channel binding
0.51	GO:0042826	histone deacetylase binding
0.50	GO:0045296	cadherin binding
0.49	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0046982	protein heterodimerization activity

0.42	GO:0005634	nucleus
0.42	GO:0090724	central region of growth cone
0.42	GO:0042470	melanosome
0.41	GO:0005739	mitochondrion
0.40	GO:0005886	plasma membrane
0.40	GO:0005871	kinesin complex
0.39	GO:0030424	axon
0.37	GO:0005829	cytosol
0.37	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome

sp|Q7ZW24|ALG11_DANRE
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
Search

ALG11

0.91	Asparagine-linked glycosylation protein 11

0.78	GO:0097502	mannosylation
0.50	GO:0033577	protein glycosylation in endoplasmic reticulum
0.47	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process

0.85

GO:0004377

GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity

0.72	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:2.4.1.131

GO:0004377

sp|Q7ZW25|CHM2A_DANRE
Charged multivesicular body protein 2a
Search

CHMP2A

0.91	Charged multivesicular body protein 2a

0.79	GO:0007034	vacuolar transport
0.54	GO:1903723	negative regulation of centriole elongation
0.53	GO:0010458	exit from mitosis
0.53	GO:0031468	nuclear envelope reassembly
0.52	GO:1903543	positive regulation of exosomal secretion
0.52	GO:1902188	positive regulation of viral release from host cell
0.51	GO:1901673	regulation of mitotic spindle assembly
0.51	GO:0000920	cell separation after cytokinesis
0.51	GO:0051291	protein heterooligomerization
0.51	GO:0010324	membrane invagination

0.52	GO:0031210	phosphatidylcholine binding
0.47	GO:0019904	protein domain specific binding

0.51	GO:0000815	ESCRT III complex
0.48	GO:0005635	nuclear envelope
0.47	GO:0048475	coated membrane
0.46	GO:0000785	chromatin
0.43	GO:0005829	cytosol
0.41	GO:0005770	late endosome
0.36	GO:0005769	early endosome
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

tr|Q7ZW27|Q7ZW27_DANRE
Coatomer subunit delta
Search

ARCN1

0.68	Coatomer subunit delta

0.81	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.65	GO:0015031	protein transport
0.55	GO:0021691	cerebellar Purkinje cell layer maturation
0.51	GO:0008344	adult locomotory behavior
0.51	GO:0043473	pigmentation
0.34	GO:0006891	intra-Golgi vesicle-mediated transport
0.34	GO:0006888	ER to Golgi vesicle-mediated transport
0.33	GO:0034613	cellular protein localization

0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0030126	COPI vesicle coat
0.73	GO:0000139	Golgi membrane
0.46	GO:0005783	endoplasmic reticulum
0.34	GO:0030133	transport vesicle
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0005829	cytosol

tr|Q7ZW29|Q7ZW29_DANRE
Histone acetyltransferase
Search

KAT7

0.59	Histone acetyltransferase

0.78	GO:0016573	histone acetylation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression

0.80	GO:0004402	histone acetyltransferase activity
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.34	GO:0005829	cytosol
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

0.80

GO:0004402

sp|Q7ZW33|UTP15_DANRE
U3 small nucleolar RNA-associated protein 15 homolog
Search

UTP15

0.86	UTP15, small subunit processome component

0.84	GO:2000234	positive regulation of rRNA processing
0.80	GO:0045943	positive regulation of transcription by RNA polymerase I
0.69	GO:0006364	rRNA processing
0.41	GO:0045766	positive regulation of angiogenesis

0.78	GO:0001650	fibrillar center
0.66	GO:0005783	endoplasmic reticulum

sp|Q7ZW34|CNTN5_DANRE
Contactin-5
Search

CNTN5

0.81	Contactin 3a, tandem duplicate 2

0.67	GO:0007411	axon guidance
0.62	GO:0007155	cell adhesion
0.52	GO:0007605	sensory perception of sound
0.43	GO:0045665	negative regulation of neuron differentiation

0.44

GO:0005112

Notch binding

0.49	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane
0.30	GO:0071944	cell periphery

tr|Q7ZW36|Q7ZW36_DANRE
Potassium voltage-gated channel, Shal-related subfamily, member 3
Search

KCND3

0.91	LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily D member 3

0.76	GO:0051260	protein homooligomerization
0.76	GO:0034765	regulation of ion transmembrane transport
0.72	GO:0071805	potassium ion transmembrane transport
0.56	GO:0001508	action potential
0.56	GO:0099625	ventricular cardiac muscle cell membrane repolarization
0.55	GO:0035637	multicellular organismal signaling
0.54	GO:0086003	cardiac muscle cell contraction
0.53	GO:0002027	regulation of heart rate
0.52	GO:0140115	export across plasma membrane
0.43	GO:0045475	locomotor rhythm

0.76	GO:0005249	voltage-gated potassium channel activity
0.53	GO:0044325	ion channel binding
0.36	GO:1905030	voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential
0.36	GO:0046872	metal ion binding
0.34	GO:0046982	protein heterodimerization activity

0.76	GO:0008076	voltage-gated potassium channel complex
0.45	GO:0030425	dendrite
0.44	GO:0044309	neuron spine
0.43	GO:0043025	neuronal cell body
0.42	GO:0045211	postsynaptic membrane
0.42	GO:0042383	sarcolemma
0.40	GO:0044298	cell body membrane
0.40	GO:0044853	plasma membrane raft
0.38	GO:0030054	cell junction
0.36	GO:0097038	perinuclear endoplasmic reticulum

sp|Q7ZW38|SPS1_DANRE
Selenide, water dikinase 1
Search

SEPHS1

0.96	Selenide, water dikinase 1

0.78	GO:0016260	selenocysteine biosynthetic process
0.57	GO:0016310	phosphorylation
0.37	GO:0001887	selenium compound metabolic process
0.34	GO:0036211	protein modification process
0.33	GO:0044267	cellular protein metabolic process

0.81	GO:0004756	selenide, water dikinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0042802	identical protein binding
0.43	GO:0046982	protein heterodimerization activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding

0.45	GO:0031965	nuclear membrane
0.38	GO:0005886	plasma membrane
0.34	GO:0005829	cytosol

0.81	EC:2.7.9.3	GO:0004756
0.81	KEGG:R03595	GO:0004756

sp|Q7ZW41|RPB7_DANRE
DNA-directed RNA polymerase II subunit RPB7
Search

POLR2G

0.86	DNA-directed RNA polymerase II polypeptide G

0.58	GO:0006351	transcription, DNA-templated
0.51	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.49	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic
0.49	GO:0045948	positive regulation of translational initiation
0.37	GO:0006915	apoptotic process
0.36	GO:0051090	regulation of DNA binding transcription factor activity
0.35	GO:0035019	somatic stem cell population maintenance
0.35	GO:0060964	regulation of gene silencing by miRNA
0.34	GO:0008543	fibroblast growth factor receptor signaling pathway
0.34	GO:0016073	snRNA metabolic process

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.51	GO:0003676	nucleic acid binding
0.48	GO:0031369	translation initiation factor binding
0.35	GO:0046982	protein heterodimerization activity

0.54	GO:0005665	DNA-directed RNA polymerase II, core complex
0.48	GO:0000932	P-body
0.36	GO:0046695	SLIK (SAGA-like) complex
0.36	GO:0000124	SAGA complex
0.36	GO:0005669	transcription factor TFIID complex
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0003899

tr|Q7ZW44|Q7ZW44_DANRE
Chromatin target of PRMT1a
Search

CHTOP

0.97	Chromatin target of PRMT1 protein isoform 1

0.85	GO:0051096	positive regulation of helicase activity
0.81	GO:0031062	positive regulation of histone methylation
0.76	GO:0032781	positive regulation of ATPase activity
0.75	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.74	GO:0008284	positive regulation of cell proliferation
0.71	GO:0051028	mRNA transport
0.70	GO:0006405	RNA export from nucleus
0.51	GO:0010467	gene expression
0.42	GO:2001141	regulation of RNA biosynthetic process
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.83	GO:0008327	methyl-CpG binding
0.41	GO:0003723	RNA binding
0.39	GO:0005515	protein binding
0.37	GO:0005509	calcium ion binding

0.79	GO:0000346	transcription export complex
0.76	GO:0016607	nuclear speck
0.74	GO:0036464	cytoplasmic ribonucleoprotein granule
0.47	GO:0005730	nucleolus

sp|Q7ZW46|S35B4_DANRE
UDP-xylose and UDP-N-acetylglucosamine transporter
Search

SLC35B4

0.94	UDP-xylose and UDP-N-acetylglucosamine transporter

0.61	GO:0015790	UDP-xylose transmembrane transport
0.60	GO:1990569	UDP-N-acetylglucosamine transmembrane transport
0.53	GO:0006111	regulation of gluconeogenesis
0.51	GO:0015783	GDP-fucose transmembrane transport
0.42	GO:0036066	protein O-linked fucosylation
0.41	GO:0015012	heparan sulfate proteoglycan biosynthetic process
0.38	GO:0008643	carbohydrate transport
0.35	GO:0015782	CMP-N-acetylneuraminate transmembrane transport
0.35	GO:0015787	UDP-glucuronic acid transmembrane transport
0.35	GO:1990570	GDP-mannose transmembrane transport

0.61	GO:0005464	UDP-xylose transmembrane transporter activity
0.61	GO:0005462	UDP-N-acetylglucosamine transmembrane transporter activity
0.51	GO:0005457	GDP-fucose transmembrane transporter activity
0.35	GO:0005456	CMP-N-acetylneuraminate transmembrane transporter activity
0.35	GO:0005461	UDP-glucuronic acid transmembrane transporter activity
0.35	GO:0005458	GDP-mannose transmembrane transporter activity
0.35	GO:0005460	UDP-glucose transmembrane transporter activity
0.33	GO:0070001	aspartic-type peptidase activity
0.33	GO:0005515	protein binding
0.33	GO:0004175	endopeptidase activity

0.50	GO:0005783	endoplasmic reticulum
0.49	GO:0005794	Golgi apparatus
0.45	GO:0031301	integral component of organelle membrane
0.43	GO:0098588	bounding membrane of organelle
0.43	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.43	GO:0031984	organelle subcompartment

sp|Q7ZW47|STAU2_DANRE
Double-stranded RNA-binding protein Staufen homolog 2
Search

STAU2

0.89	Double-stranded RNA-binding protein Staufen

0.38	GO:0008354	germ cell migration
0.37	GO:0007281	germ cell development

0.59

GO:0003723

RNA binding

0.37

GO:0005874

microtubule

sp|Q7ZW63|NUF2_DANRE
Kinetochore protein Nuf2
Search

NUF2

0.79	Kinetochore protein Nuf2-A

0.75	GO:0000278	mitotic cell cycle
0.50	GO:0007507	heart development
0.40	GO:0051301	cell division

0.35

GO:0005515

protein binding

0.77	GO:0000775	chromosome, centromeric region
0.42	GO:0000793	condensed chromosome
0.40	GO:0005634	nucleus
0.40	GO:0043234	protein complex
0.35	GO:0005815	microtubule organizing center
0.32	GO:0005737	cytoplasm

tr|Q7ZW68|Q7ZW68_DANRE
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b
Search

0.26	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b

0.82	GO:0007253	cytoplasmic sequestering of NF-kappaB
0.82	GO:1903707	negative regulation of hemopoiesis
0.81	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway
0.81	GO:0010745	negative regulation of macrophage derived foam cell differentiation
0.80	GO:0010875	positive regulation of cholesterol efflux
0.80	GO:0010888	negative regulation of lipid storage
0.79	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway
0.77	GO:0035994	response to muscle stretch
0.77	GO:0032495	response to muramyl dipeptide
0.77	GO:0033209	tumor necrosis factor-mediated signaling pathway

0.79	GO:0051059	NF-kappaB binding
0.77	GO:0008139	nuclear localization sequence binding
0.71	GO:0031625	ubiquitin protein ligase binding
0.66	GO:0042802	identical protein binding
0.42	GO:0031072	heat shock protein binding
0.42	GO:0032403	protein complex binding
0.35	GO:0016301	kinase activity

0.62	GO:0005829	cytosol
0.56	GO:0005634	nucleus
0.51	GO:0005886	plasma membrane
0.43	GO:0033256	I-kappaB/NF-kappaB complex

sp|Q7ZW77|MSMO1_DANRE
Methylsterol monooxygenase 1
Search

MSMO1

0.93	Methylsterol monooxygenase 1

0.65	GO:0008610	lipid biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.50	GO:0016125	sterol metabolic process
0.47	GO:1901617	organic hydroxy compound biosynthetic process
0.40	GO:1901362	organic cyclic compound biosynthetic process
0.34	GO:1902652	secondary alcohol metabolic process
0.34	GO:0006631	fatty acid metabolic process
0.33	GO:0044283	small molecule biosynthetic process
0.32	GO:0006665	sphingolipid metabolic process
0.32	GO:0044249	cellular biosynthetic process

0.62	GO:0005506	iron ion binding
0.57	GO:0004497	monooxygenase activity
0.45	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0004318	enoyl-[acyl-carrier-protein] reductase (NADH) activity
0.32	GO:0000170	sphingosine hydroxylase activity

0.47	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005835	fatty acid synthase complex
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.45

EC:1.14

GO:0016705

sp|Q7ZW78|RN181_DANRE
E3 ubiquitin-protein ligase RNF181
Search

RNF181

0.51	E3 ubiquitin protein ligase

0.63	GO:0051865	protein autoubiquitination
0.57	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.56	GO:0000209	protein polyubiquitination
0.54	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.37	GO:0016192	vesicle-mediated transport
0.37	GO:0009737	response to abscisic acid
0.37	GO:0010200	response to chitin
0.36	GO:0009414	response to water deprivation
0.35	GO:0009788	negative regulation of abscisic acid-activated signaling pathway
0.34	GO:0097306	cellular response to alcohol

0.60	GO:0004842	ubiquitin-protein transferase activity
0.54	GO:0016874	ligase activity
0.54	GO:0061659	ubiquitin-like protein ligase activity
0.39	GO:0046872	metal ion binding

0.34	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.54	EC:6	GO:0016874
0.60	KEGG:R03876	GO:0004842

tr|Q7ZW81|Q7ZW81_DANRE
Mibp protein
Search

NMRK2

0.95	Muscle-specific beta 1 integrin binding protein 2

0.52	GO:0016310	phosphorylation
0.48	GO:0007229	integrin-mediated signaling pathway
0.46	GO:0070831	basement membrane assembly
0.45	GO:0007045	cell-substrate adherens junction assembly
0.43	GO:0007517	muscle organ development
0.43	GO:0045662	negative regulation of myoblast differentiation
0.34	GO:0009435	NAD biosynthetic process
0.33	GO:0055114	oxidation-reduction process

0.55	GO:0016301	kinase activity
0.36	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
0.35	GO:0005507	copper ion binding
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005654	nucleoplasm
0.36	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:1.4.3

GO:0016641

tr|Q7ZW82|Q7ZW82_DANRE
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
Search

GNAI1

0.79	Guanine nucleotide binding protein alpha inhibiting 1

0.82	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.54	GO:1904778	positive regulation of protein localization to cell cortex
0.53	GO:0007212	dopamine receptor signaling pathway
0.53	GO:0016239	positive regulation of macroautophagy
0.51	GO:0060236	regulation of mitotic spindle organization
0.51	GO:0051301	cell division
0.49	GO:0046039	GTP metabolic process
0.43	GO:1904321	response to forskolin
0.42	GO:0043949	regulation of cAMP-mediated signaling
0.42	GO:1901655	cellular response to ketone

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0001664	G-protein coupled receptor binding
0.41	GO:0032794	GTPase activating protein binding
0.37	GO:0000287	magnesium ion binding

0.60	GO:0030496	midbody
0.57	GO:0005813	centrosome
0.54	GO:0005730	nucleolus
0.51	GO:0099738	cell cortex region
0.50	GO:1905360	GTPase complex
0.49	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.48	GO:0000139	Golgi membrane
0.47	GO:0005789	endoplasmic reticulum membrane
0.44	GO:0098797	plasma membrane protein complex
0.39	GO:0045121	membrane raft

tr|Q7ZW85|Q7ZW85_DANRE
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a
Search

0.92	DnaJ like protein subfamily C member 5

0.63	GO:0043524	negative regulation of neuron apoptotic process
0.39	GO:0007268	chemical synaptic transmission
0.37	GO:0009116	nucleoside metabolic process
0.35	GO:0016310	phosphorylation

0.46	GO:0043008	ATP-dependent protein binding
0.38	GO:0008270	zinc ion binding
0.35	GO:0016301	kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003677	DNA binding

0.61	GO:0008021	synaptic vesicle
0.46	GO:0005886	plasma membrane
0.44	GO:0043195	terminal bouton
0.44	GO:0042470	melanosome
0.40	GO:0005765	lysosomal membrane
0.39	GO:0070062	extracellular exosome
0.36	GO:0005739	mitochondrion
0.35	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q7ZW86|CWC27_DANRE
Peptidyl-prolyl cis-trans isomerase CWC27 homolog
Search

CWC27

0.82	Peptidyl-prolyl cis-trans isomerase SDCCAG10

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.68	GO:0006457	protein folding
0.36	GO:0006506	GPI anchor biosynthetic process
0.34	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0072383	plus-end-directed vesicle transport along microtubule
0.34	GO:0044837	actomyosin contractile ring organization
0.34	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis
0.32	GO:0034220	ion transmembrane transport
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.37	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity
0.34	GO:0005515	protein binding
0.33	GO:0005230	extracellular ligand-gated ion channel activity
0.33	GO:0003777	microtubule motor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.53	GO:0071013	catalytic step 2 spliceosome
0.48	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.72

GO:0003755

tr|Q7ZW92|Q7ZW92_DANRE
Serine/threonine kinase receptor associated protein
Search

STRAP

0.90	serine-threonine kinase receptor-associated protein-like

0.58	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation
0.57	GO:0030277	maintenance of gastrointestinal epithelium
0.57	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.56	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.56	GO:0010633	negative regulation of epithelial cell migration
0.55	GO:0050680	negative regulation of epithelial cell proliferation
0.54	GO:0000387	spliceosomal snRNP assembly
0.53	GO:0000122	negative regulation of transcription by RNA polymerase II
0.53	GO:0016310	phosphorylation

0.55	GO:0016301	kinase activity
0.50	GO:0005102	receptor binding
0.34	GO:0003723	RNA binding

0.57	GO:0032797	SMN complex
0.57	GO:0034719	SMN-Sm protein complex
0.48	GO:0005829	cytosol
0.48	GO:0005654	nucleoplasm

tr|Q7ZW93|Q7ZW93_DANRE
Zgc:56676
Search

EIF1B

0.92	Eukaryotic translation initiation factor 1

0.72	GO:0006413	translational initiation
0.47	GO:0006446	regulation of translational initiation
0.45	GO:0009048	dosage compensation by inactivation of X chromosome
0.34	GO:0006886	intracellular protein transport

0.73	GO:0003743	translation initiation factor activity
0.35	GO:0017137	Rab GTPase binding
0.32	GO:0016787	hydrolase activity

0.41	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.32

GO:0016787

tr|Q7ZW94|Q7ZW94_DANRE
Signal recognition particle 9 kDa protein
Search

SRP9

0.80	Signal recognition particle 9

0.79	GO:0045900	negative regulation of translational elongation
0.75	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.45	GO:0065002	intracellular protein transmembrane transport

0.78	GO:0008312	7S RNA binding
0.48	GO:0005047	signal recognition particle binding
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.77	GO:0005786	signal recognition particle, endoplasmic reticulum targeting
0.48	GO:0005785	signal recognition particle receptor complex
0.36	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol

0.32

GO:0016787

tr|Q7ZW95|Q7ZW95_DANRE
Ribosomal protein L4
Search

RPL4

0.72	Ribosomal protein L4-b

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0003360	brainstem development
0.35	GO:0045773	positive regulation of axon extension
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0071417	cellular response to organonitrogen compound
0.34	GO:0007420	brain development
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.64	GO:0003735	structural constituent of ribosome
0.39	GO:0003723	RNA binding
0.35	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.47	GO:0005791	rough endoplasmic reticulum
0.43	GO:0044445	cytosolic part
0.40	GO:0005634	nucleus
0.39	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0031672	A band
0.34	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q7ZW98|AP2MB_DANRE
AP-2 complex subunit mu-B
Search

AP2M1

0.87	AP-2 complex subunit mu-B

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.41	GO:0098657	import into cell
0.38	GO:0097494	regulation of vesicle size
0.38	GO:1900244	positive regulation of synaptic vesicle endocytosis
0.38	GO:1903077	negative regulation of protein localization to plasma membrane
0.38	GO:0002092	positive regulation of receptor internalization
0.38	GO:0016050	vesicle organization
0.38	GO:0036465	synaptic vesicle recycling
0.37	GO:0097480	establishment of synaptic vesicle localization

0.71	GO:0008289	lipid binding
0.50	GO:0097718	disordered domain specific binding
0.39	GO:0050750	low-density lipoprotein particle receptor binding
0.38	GO:0005048	signal sequence binding
0.37	GO:0044325	ion channel binding
0.35	GO:0035615	clathrin adaptor activity
0.35	GO:0004222	metalloendopeptidase activity
0.34	GO:0008270	zinc ion binding
0.32	GO:0005215	transporter activity

0.79	GO:0030131	clathrin adaptor complex
0.43	GO:0005905	clathrin-coated pit
0.41	GO:0005739	mitochondrion
0.41	GO:0005886	plasma membrane
0.38	GO:0030128	clathrin coat of endocytic vesicle
0.38	GO:0043195	terminal bouton
0.36	GO:0044421	extracellular region part
0.35	GO:0036020	endolysosome membrane
0.34	GO:0030141	secretory granule
0.33	GO:0005829	cytosol

0.35

GO:0004222

sp|Q7ZWA3|RBMX_DANRE
RNA-binding motif protein, X chromosome
Search

RBMX

0.90	RNA binding motif protein, X-linked

0.51	GO:0006509	membrane protein ectodomain proteolysis
0.50	GO:0071347	cellular response to interleukin-1
0.50	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.46	GO:0006366	transcription by RNA polymerase II
0.46	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0051259	protein oligomerization
0.45	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.45	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.44	GO:0008380	RNA splicing
0.43	GO:0006397	mRNA processing

0.58	GO:0003723	RNA binding
0.49	GO:0001047	core promoter binding
0.47	GO:0003682	chromatin binding
0.43	GO:0019904	protein domain specific binding
0.42	GO:0042802	identical protein binding

0.53	GO:0044530	supraspliceosomal complex
0.50	GO:0005719	nuclear euchromatin
0.49	GO:0071013	catalytic step 2 spliceosome
0.48	GO:0070062	extracellular exosome
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|Q7ZWA9|Q7ZWA9_DANRE
Eukaryotic translation initiation factor 5
Search

EIF5

0.83	Eukaryotic translation initiation factor

0.72	GO:0006413	translational initiation
0.46	GO:0006446	regulation of translational initiation
0.37	GO:0090630	activation of GTPase activity
0.37	GO:0002181	cytoplasmic translation
0.36	GO:0022618	ribonucleoprotein complex assembly

0.72	GO:0003743	translation initiation factor activity
0.47	GO:0045296	cadherin binding
0.39	GO:0071074	eukaryotic initiation factor eIF2 binding
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003924	GTPase activity

0.43	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane
0.34	GO:0005634	nucleus

tr|Q7ZWB1|Q7ZWB1_DANRE
Cyclin-dependent kinase 2
Search

CDK2

0.91	Porcine cyclin dependent kinase 2

0.62	GO:0006468	protein phosphorylation
0.54	GO:0000082	G1/S transition of mitotic cell cycle
0.53	GO:0032298	positive regulation of DNA-dependent DNA replication initiation
0.53	GO:0008284	positive regulation of cell proliferation
0.52	GO:0051726	regulation of cell cycle
0.51	GO:0007099	centriole replication
0.50	GO:0007265	Ras protein signal transduction
0.50	GO:0060968	regulation of gene silencing
0.50	GO:0018209	peptidyl-serine modification
0.48	GO:0000122	negative regulation of transcription by RNA polymerase II

0.67	GO:0004674	protein serine/threonine kinase activity
0.58	GO:0097472	cyclin-dependent protein kinase activity
0.54	GO:0030332	cyclin binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.52	GO:0035173	histone kinase activity
0.48	GO:0019904	protein domain specific binding
0.35	GO:0046872	metal ion binding

0.56	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.54	GO:0000806	Y chromosome
0.53	GO:0000805	X chromosome
0.52	GO:0015030	Cajal body
0.49	GO:0005815	microtubule organizing center
0.49	GO:0000781	chromosome, telomeric region
0.48	GO:0005768	endosome
0.48	GO:0005667	transcription factor complex
0.48	GO:0000793	condensed chromosome
0.35	GO:0005829	cytosol

0.67

GO:0004674

sp|Q7ZWB2|UBL4A_DANRE
Ubiquitin-like protein 4A
Search

UBL4A

0.96	Ubiquitin like 4A

0.84	GO:0071816	tail-anchored membrane protein insertion into ER membrane
0.37	GO:1903955	positive regulation of protein targeting to mitochondrion
0.35	GO:0055085	transmembrane transport
0.35	GO:0036211	protein modification process
0.34	GO:0044267	cellular protein metabolic process

0.65	GO:0051087	chaperone binding
0.37	GO:0019787	ubiquitin-like protein transferase activity

0.86	GO:0071818	BAT3 complex
0.60	GO:0005654	nucleoplasm
0.36	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

tr|Q7ZWB4|Q7ZWB4_DANRE
ADP-ribosylation factor-like 6 interacting protein
Search

ARL6IP1

0.97	ADP ribosylation factor like GTPase 6 interacting protein 1

0.56	GO:0002038	positive regulation of L-glutamate transport
0.51	GO:0006613	cotranslational protein targeting to membrane
0.45	GO:0001755	neural crest cell migration
0.44	GO:0060042	retina morphogenesis in camera-type eye
0.44	GO:0071787	endoplasmic reticulum tubular network formation
0.43	GO:1990809	endoplasmic reticulum tubular network membrane organization
0.42	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.37	GO:0006915	apoptotic process
0.36	GO:0006412	translation
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.39	GO:0042802	identical protein binding
0.37	GO:0003735	structural constituent of ribosome
0.33	GO:0003723	RNA binding
0.32	GO:0046872	metal ion binding

0.56	GO:0005784	Sec61 translocon complex
0.45	GO:0005829	cytosol
0.40	GO:0030176	integral component of endoplasmic reticulum membrane
0.37	GO:0005840	ribosome

tr|Q7ZWB6|Q7ZWB6_DANRE
Thioredoxin interacting protein
Search

TXNIP

0.80	Thioredoxin interacting protein a

0.61	GO:0007165	signal transduction
0.56	GO:0071228	cellular response to tumor cell
0.52	GO:0030216	keratinocyte differentiation
0.51	GO:0051782	negative regulation of cell division
0.50	GO:0006606	protein import into nucleus
0.49	GO:0000122	negative regulation of transcription by RNA polymerase II
0.48	GO:0050790	regulation of catalytic activity
0.46	GO:0006979	response to oxidative stress
0.46	GO:0044092	negative regulation of molecular function
0.44	GO:0140112	extracellular vesicle biogenesis

0.49	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0004857	enzyme inhibitor activity
0.45	GO:1990756	protein binding, bridging involved in substrate recognition for ubiquitination
0.34	GO:0016286	small conductance calcium-activated potassium channel activity
0.34	GO:0036122	BMP binding
0.34	GO:0031699	beta-3 adrenergic receptor binding
0.34	GO:0015026	coreceptor activity
0.34	GO:0003729	mRNA binding
0.34	GO:0005516	calmodulin binding
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity

0.42	GO:1903561	extracellular vesicle
0.41	GO:0031410	cytoplasmic vesicle
0.39	GO:0012505	endomembrane system
0.37	GO:0005758	mitochondrial intermembrane space
0.37	GO:0005886	plasma membrane
0.35	GO:0005634	nucleus
0.34	GO:0005829	cytosol
0.33	GO:0043235	receptor complex
0.30	GO:0016021	integral component of membrane

0.33

GO:0003899

sp|Q7ZWB7|BBS5_DANRE
Bardet-Biedl syndrome 5 protein homolog
Search

BBS5

0.97	Bardet-Biedl syndrome 5 protein homolog

0.53	GO:0060271	cilium assembly
0.49	GO:0072116	pronephros formation
0.48	GO:0051877	pigment granule aggregation in cell center
0.47	GO:0046907	intracellular transport
0.47	GO:0032401	establishment of melanosome localization
0.46	GO:0070121	Kupffer's vesicle development
0.46	GO:0001947	heart looping
0.45	GO:0048749	compound eye development
0.45	GO:0007369	gastrulation
0.38	GO:0035914	skeletal muscle cell differentiation

0.55	GO:0032266	phosphatidylinositol-3-phosphate binding
0.50	GO:0001103	RNA polymerase II repressing transcription factor binding

0.84	GO:0034464	BBSome
0.55	GO:0036064	ciliary basal body
0.50	GO:0005930	axoneme
0.40	GO:0060170	ciliary membrane
0.36	GO:0031430	M band
0.36	GO:0033017	sarcoplasmic reticulum membrane
0.36	GO:0031463	Cul3-RING ubiquitin ligase complex
0.35	GO:0005829	cytosol
0.34	GO:0005634	nucleus

tr|Q7ZWC2|Q7ZWC2_DANRE
Monoglyceride lipase
Search

MGLL

0.89	Monoglyceride lipase

0.55	GO:0009966	regulation of signal transduction
0.51	GO:0006629	lipid metabolic process
0.47	GO:0051930	regulation of sensory perception of pain
0.46	GO:0006690	icosanoid metabolic process
0.45	GO:0050727	regulation of inflammatory response
0.44	GO:0060292	long term synaptic depression
0.43	GO:0030516	regulation of axon extension
0.41	GO:0072330	monocarboxylic acid biosynthetic process
0.40	GO:0044248	cellular catabolic process
0.39	GO:0097756	negative regulation of blood vessel diameter

0.68	GO:0047372	acylglycerol lipase activity
0.43	GO:0042803	protein homodimerization activity
0.39	GO:0004622	lysophospholipase activity

0.64	GO:0005654	nucleoplasm
0.45	GO:0043196	varicosity
0.43	GO:0019898	extrinsic component of membrane
0.41	GO:0005829	cytosol
0.41	GO:0045202	synapse
0.39	GO:0005811	lipid droplet
0.37	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.68

EC:3.1.1.23

GO:0047372

tr|Q7ZWC3|Q7ZWC3_DANRE
Nudix (Nucleoside diphosphate linked moiety X)-type motif 1
Search

NUDT1

0.64	Nudix (nucleoside diphosphate-linked moiety X)-type motif 1

0.65	GO:0006281	DNA repair
0.55	GO:0046061	dATP catabolic process
0.53	GO:0006203	dGTP catabolic process
0.52	GO:0042262	DNA protection
0.38	GO:0008584	male gonad development
0.38	GO:0046686	response to cadmium ion
0.38	GO:0007568	aging
0.35	GO:0034656	nucleobase-containing small molecule catabolic process
0.33	GO:0006979	response to oxidative stress

0.82	GO:0008413	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
0.55	GO:0036219	GTP diphosphatase activity
0.55	GO:0035539	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity
0.53	GO:0047693	ATP diphosphatase activity
0.50	GO:0030515	snoRNA binding
0.45	GO:0003924	GTPase activity
0.39	GO:0044714	2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity
0.39	GO:0044713	2-hydroxy-adenosine triphosphate pyrophosphatase activity
0.38	GO:0050072	m7G(5')pppN diphosphatase activity
0.33	GO:0046872	metal ion binding

0.48	GO:0005759	mitochondrial matrix
0.46	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.38	GO:0001669	acrosomal vesicle
0.37	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:0031967	organelle envelope
0.35	GO:0031090	organelle membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.82	EC:3.6.1	GO:0008413
0.55	KEGG:R00426	GO:0036219

sp|Q7ZWC4|PELO_DANRE
Protein pelota homolog
Search

tr|Q7ZWC9|Q7ZWC9_DANRE
1-acylglycerol-3-phosphate O-acyltransferase 3
Search

AGPAT3

0.88	1-acylglycerol-3-phosphate O-acyltransferase 3

0.30

GO:0008152

metabolic process

0.63

GO:0016746

transferase activity, transferring acyl groups

0.56	GO:0005783	endoplasmic reticulum
0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.63

EC:2.3

GO:0016746

tr|Q7ZWD3|Q7ZWD3_DANRE
Eif2s1l protein
Search

EIF2S1

0.87	Eukaryotic translation initiation factor 2 subunit alpha

0.72	GO:0006413	translational initiation
0.60	GO:0032057	negative regulation of translational initiation in response to stress
0.56	GO:0034198	cellular response to amino acid starvation
0.55	GO:0034644	cellular response to UV
0.55	GO:1901216	positive regulation of neuron death
0.53	GO:0034976	response to endoplasmic reticulum stress
0.53	GO:0046777	protein autophosphorylation
0.40	GO:2000676	positive regulation of type B pancreatic cell apoptotic process
0.40	GO:0071287	cellular response to manganese ion
0.40	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity

0.73	GO:0003743	translation initiation factor activity
0.52	GO:0043022	ribosome binding
0.36	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.59	GO:0005850	eukaryotic translation initiation factor 2 complex
0.58	GO:0005851	eukaryotic translation initiation factor 2B complex
0.54	GO:0010494	cytoplasmic stress granule
0.48	GO:0043614	multi-eIF complex
0.46	GO:0033290	eukaryotic 48S preinitiation complex
0.44	GO:0005634	nucleus
0.41	GO:0044207	translation initiation ternary complex
0.40	GO:0005840	ribosome
0.40	GO:0097451	glial limiting end-foot
0.36	GO:0070062	extracellular exosome

sp|Q7ZWD4|UAP1L_DANRE
UDP-N-acetylhexosamine pyrophosphorylase-like protein 1
Search

UAP1L1

0.90	UDP-N-acetylhexosamine pyrophosphorylase

0.46	GO:0006048	UDP-N-acetylglucosamine biosynthetic process
0.36	GO:0016310	phosphorylation
0.35	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.35	GO:0018212	peptidyl-tyrosine modification
0.35	GO:0006491	N-glycan processing
0.34	GO:0038065	collagen-activated signaling pathway
0.32	GO:0006508	proteolysis

0.75	GO:0070569	uridylyltransferase activity
0.37	GO:0042802	identical protein binding
0.36	GO:0016301	kinase activity
0.36	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.35	GO:0005509	calcium ion binding
0.34	GO:0038064	collagen receptor activity
0.34	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0017171	serine hydrolase activity
0.33	GO:0032559	adenyl ribonucleotide binding

0.43	GO:0005829	cytosol
0.36	GO:0005654	nucleoplasm
0.35	GO:0005886	plasma membrane
0.34	GO:0000139	Golgi membrane
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.36	EC:3.2.1.113	GO:0004571
0.36	KEGG:R05982 KEGG:R06722	GO:0004571

tr|Q7ZWD8|Q7ZWD8_DANRE
Cfl1 protein
Search

CFL2

0.89	Cofilin 1 (non-muscle), like

0.84	GO:0030042	actin filament depolymerization
0.54	GO:0030836	positive regulation of actin filament depolymerization
0.53	GO:0046716	muscle cell cellular homeostasis
0.52	GO:0045214	sarcomere organization
0.51	GO:0007519	skeletal muscle tissue development
0.42	GO:0070586	cell-cell adhesion involved in gastrulation
0.41	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.40	GO:0061371	determination of heart left/right asymmetry
0.39	GO:0060271	cilium assembly
0.38	GO:0001842	neural fold formation

0.74	GO:0003779	actin binding
0.49	GO:0032403	protein complex binding
0.35	GO:0005102	receptor binding
0.34	GO:0019903	protein phosphatase binding
0.34	GO:1902936	phosphatidylinositol bisphosphate binding
0.33	GO:0046872	metal ion binding
0.32	GO:0016787	hydrolase activity
0.32	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity
0.32	GO:0030554	adenyl nucleotide binding
0.31	GO:0097367	carbohydrate derivative binding

0.74	GO:0015629	actin cytoskeleton
0.51	GO:0030018	Z disc
0.39	GO:0016363	nuclear matrix
0.37	GO:0005615	extracellular space
0.37	GO:0030027	lamellipodium
0.36	GO:0030863	cortical cytoskeleton
0.36	GO:0005911	cell-cell junction
0.35	GO:1903561	extracellular vesicle
0.35	GO:0044430	cytoskeletal part
0.34	GO:0043197	dendritic spine

0.32

GO:0016787

tr|Q7ZWE1|Q7ZWE1_DANRE
PWP1 homolog (S. cerevisiae)
Search

PWP1

0.92	Periodic tryptophan protein 1

0.85	GO:0033140	negative regulation of peptidyl-serine phosphorylation of STAT protein
0.82	GO:2000738	positive regulation of stem cell differentiation
0.82	GO:0034773	histone H4-K20 trimethylation
0.35	GO:0006351	transcription, DNA-templated

0.86

GO:1990889

H4K20me3 modified histone binding

0.69	GO:0005730	nucleolus
0.67	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

sp|Q7ZWE3|LARP7_DANRE
La-related protein 7
Search

LARP7

0.79	La ribonucleoprotein domain family member 7

0.61	GO:0006396	RNA processing
0.39	GO:0061026	cardiac muscle tissue regeneration
0.38	GO:0060043	regulation of cardiac muscle cell proliferation
0.35	GO:0036093	germ cell proliferation
0.35	GO:0035562	negative regulation of chromatin binding
0.35	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.34	GO:0000122	negative regulation of transcription by RNA polymerase II
0.32	GO:0006468	protein phosphorylation

0.59	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.32	GO:0004674	protein serine/threonine kinase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0005634	nucleus
0.60	GO:0030529	intracellular ribonucleoprotein complex
0.44	GO:0031974	membrane-enclosed lumen
0.44	GO:0005829	cytosol
0.43	GO:0019013	viral nucleocapsid
0.41	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0004674

sp|Q7ZWE6|DTB1A_DANRE
Dysbindin-A
Search

DTNBP1

0.94	Dystrobrevin binding protein 1

0.56	GO:0060155	platelet dense granule organization
0.56	GO:0048490	anterograde synaptic vesicle transport
0.56	GO:0001956	positive regulation of neurotransmitter secretion
0.55	GO:0014059	regulation of dopamine secretion
0.53	GO:0043506	regulation of JUN kinase activity
0.53	GO:0048813	dendrite morphogenesis
0.53	GO:0032091	negative regulation of protein binding
0.51	GO:0007596	blood coagulation
0.51	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.50	GO:0031532	actin cytoskeleton reorganization

0.35	GO:0005515	protein binding
0.33	GO:0004749	ribose phosphate diphosphokinase activity
0.32	GO:0000287	magnesium ion binding

0.56	GO:0030672	synaptic vesicle membrane
0.54	GO:1904115	axon cytoplasm
0.53	GO:0031083	BLOC-1 complex
0.53	GO:0043197	dendritic spine
0.53	GO:0014069	postsynaptic density
0.53	GO:0030426	growth cone
0.52	GO:0016528	sarcoplasm
0.52	GO:0042383	sarcolemma
0.52	GO:0030496	midbody
0.48	GO:0005789	endoplasmic reticulum membrane

0.33	EC:2.7.6.1	GO:0004749
0.33	KEGG:R01049	GO:0004749

sp|Q7ZWE7|NOL12_DANRE
Nucleolar protein 12
Search

NOL12

0.83	Nucleolar protein 12

0.41	GO:0006364	rRNA processing
0.38	GO:0032956	regulation of actin cytoskeleton organization

0.48	GO:0019843	rRNA binding
0.40	GO:0003697	single-stranded DNA binding
0.38	GO:0051015	actin filament binding
0.33	GO:0016740	transferase activity

0.70	GO:0005730	nucleolus
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016740

sp|Q7ZWE9|KCY_DANRE
UMP-CMP kinase
Search

CMPK1

0.79	Cytidine/uridine monophosphate kinase 1

0.72	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process
0.68	GO:0006221	pyrimidine nucleotide biosynthetic process
0.68	GO:0046939	nucleotide phosphorylation
0.59	GO:0009132	nucleoside diphosphate metabolic process
0.47	GO:0009142	nucleoside triphosphate biosynthetic process
0.39	GO:0046940	nucleoside monophosphate phosphorylation
0.35	GO:0018963	phthalate metabolic process
0.35	GO:0015949	nucleobase-containing small molecule interconversion
0.35	GO:0046134	pyrimidine nucleoside biosynthetic process
0.35	GO:0009218	pyrimidine ribonucleotide metabolic process

0.78	GO:0004127	cytidylate kinase activity
0.77	GO:0009041	uridylate kinase activity
0.66	GO:0004550	nucleoside diphosphate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0050145	nucleoside phosphate kinase activity
0.34	GO:0004849	uridine kinase activity

0.56	GO:0005634	nucleus
0.46	GO:0031974	membrane-enclosed lumen
0.45	GO:0005737	cytoplasm
0.42	GO:0043232	intracellular non-membrane-bounded organelle
0.42	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.33	GO:0031514	motile cilium
0.30	GO:0016020	membrane

0.78

EC:2.7.4.14

GO:0004127

sp|Q7ZWF0|RAE1L_DANRE
mRNA export factor
Search

RAE1

0.94	mRNA export factor

0.81	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.76	GO:0051028	mRNA transport
0.75	GO:0006405	RNA export from nucleus
0.55	GO:0060236	regulation of mitotic spindle organization
0.54	GO:0010467	gene expression
0.50	GO:0071407	cellular response to organic cyclic compound
0.49	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
0.47	GO:0006606	protein import into nucleus
0.39	GO:0007049	cell cycle
0.39	GO:0051301	cell division

0.47	GO:0043130	ubiquitin binding
0.44	GO:0003723	RNA binding
0.35	GO:0008017	microtubule binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.30	GO:0003824	catalytic activity

0.56	GO:0097431	mitotic spindle pole
0.53	GO:0001650	fibrillar center
0.53	GO:0005643	nuclear pore
0.35	GO:0005737	cytoplasm
0.33	GO:0005694	chromosome
0.33	GO:0044215	other organism

sp|Q7ZWF4|RN145_DANRE
RING finger protein 145
Search

RNF145

0.97	RING finger protein 145

0.47	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.47	GO:0000209	protein polyubiquitination
0.45	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.35	GO:0061515	myeloid cell development

0.60	GO:0008270	zinc ion binding
0.45	GO:0061630	ubiquitin protein ligase activity

0.30

GO:0044425

membrane part

sp|Q7ZWG6|PCFT_DANRE
Proton-coupled folate transporter
Search

SLC46A1

0.84	Proton-coupled folate transporter

0.62	GO:1904447	folic acid import across plasma membrane
0.61	GO:0051958	methotrexate transport
0.53	GO:0015886	heme transport
0.46	GO:1902600	hydrogen ion transmembrane transport
0.36	GO:0098829	intestinal folate absorption
0.34	GO:0046655	folic acid metabolic process
0.34	GO:0006879	cellular iron ion homeostasis

0.60	GO:0008517	folic acid transmembrane transporter activity
0.53	GO:0015232	heme transporter activity
0.46	GO:0015078	hydrogen ion transmembrane transporter activity
0.42	GO:0005542	folic acid binding
0.41	GO:0015350	methotrexate transmembrane transporter activity

0.56	GO:0016324	apical plasma membrane
0.40	GO:0031526	brush border membrane
0.39	GO:0005737	cytoplasm
0.36	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|Q7ZWG9|SGMR1_DANRE
Sigma non-opioid intracellular receptor 1
Search

SIGMAR1

0.97	Sigma non-opioid intracellular receptor 1

0.64	GO:0070207	protein homotrimerization
0.62	GO:0043523	regulation of neuron apoptotic process
0.47	GO:0006869	lipid transport
0.41	GO:0038003	opioid receptor signaling pathway
0.38	GO:0007399	nervous system development
0.37	GO:0009611	response to wounding

0.49	GO:0004872	receptor activity
0.38	GO:0042802	identical protein binding
0.37	GO:0004871	signal transducer activity
0.33	GO:0016853	isomerase activity
0.33	GO:0008144	drug binding
0.32	GO:0003677	DNA binding

0.62	GO:0014069	postsynaptic density
0.60	GO:0005635	nuclear envelope
0.58	GO:0005783	endoplasmic reticulum
0.48	GO:0031968	organelle outer membrane
0.46	GO:0031410	cytoplasmic vesicle
0.46	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.45	GO:0030426	growth cone
0.45	GO:0005811	lipid droplet
0.44	GO:0031984	organelle subcompartment
0.44	GO:0045211	postsynaptic membrane

0.33

GO:0016853

tr|Q7ZWH4|Q7ZWH4_DANRE
Actin-related protein 2/3 complex subunit 5
Search

ARPC5

0.71	Actin-related protein 2/3 complex subunit 5

0.81	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.53	GO:0016477	cell migration
0.39	GO:0021769	orbitofrontal cortex development
0.38	GO:0051639	actin filament network formation
0.38	GO:0030011	maintenance of cell polarity
0.38	GO:0097581	lamellipodium organization
0.38	GO:0061842	microtubule organizing center localization
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0048013	ephrin receptor signaling pathway

0.53	GO:0051015	actin filament binding
0.49	GO:0005200	structural constituent of cytoskeleton

0.80	GO:0005885	Arp2/3 protein complex
0.51	GO:0030027	lamellipodium
0.38	GO:0030426	growth cone
0.37	GO:0005737	cytoplasm
0.36	GO:0097708	intracellular vesicle
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0012505	endomembrane system
0.35	GO:0031983	vesicle lumen
0.33	GO:0070013	intracellular organelle lumen

sp|Q7ZWI4|GSKIP_DANRE
GSK3-beta interaction protein
Search

GSKIP

0.96	GSK3-beta interaction protein isoform X2

0.82	GO:0060828	regulation of canonical Wnt signaling pathway
0.41	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress
0.40	GO:0030177	positive regulation of Wnt signaling pathway
0.40	GO:0006469	negative regulation of protein kinase activity

0.85	GO:0051018	protein kinase A binding
0.40	GO:0004860	protein kinase inhibitor activity

0.36	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

sp|Q7ZWJ3|OSTC_DANRE
Oligosaccharyltransferase complex subunit ostc
Search

OSTC

0.93	Oligosaccharyltransferase complex non-catalytic subunit

0.38	GO:0006486	protein glycosylation
0.35	GO:0018196	peptidyl-asparagine modification
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression

0.44	GO:0016740	transferase activity
0.34	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.52	GO:0008250	oligosaccharyltransferase complex
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.44

GO:0016740

sp|Q7ZWJ4|RL18A_DANRE
60S ribosomal protein L18a
Search

0.69	Ribosomal protein L18a variant (Fragment)

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.37	GO:0097327	response to antineoplastic agent
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis

0.63	GO:0003735	structural constituent of ribosome
0.41	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.49	GO:0044445	cytosolic part
0.48	GO:0005844	polysome
0.42	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q7ZWJ7|RL34_DANRE
60S ribosomal protein L34
Search

RPL34

0.75	Ribosomal protein L34

0.58	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.40	GO:0042254	ribosome biogenesis
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.34	GO:0016072	rRNA metabolic process

0.61	GO:0003735	structural constituent of ribosome
0.46	GO:0045296	cadherin binding
0.38	GO:0003723	RNA binding

0.59	GO:0005840	ribosome
0.41	GO:0044445	cytosolic part
0.40	GO:0005739	mitochondrion
0.38	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q7ZWK8|OTOP1_DANRE
Otopetrin-1
Search

OTOP1

0.97	LOW QUALITY PROTEIN: otopetrin-1

0.41	GO:0031214	biomineral tissue development
0.40	GO:0042472	inner ear morphogenesis
0.38	GO:0048840	otolith development
0.38	GO:0009590	detection of gravity
0.37	GO:0007212	dopamine receptor signaling pathway
0.37	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.36	GO:0048646	anatomical structure formation involved in morphogenesis

0.38	GO:0004952	dopamine neurotransmitter receptor activity
0.32	GO:0003676	nucleic acid binding

0.38	GO:0005615	extracellular space
0.35	GO:0005887	integral component of plasma membrane
0.32	GO:0005622	intracellular

tr|Q7ZYW0|Q7ZYW0_DANRE
Ribonucleotide reductase M2 b
Search

RRM2B

0.89	Ribonucleoside-diphosphate reductase subunit M2 B

0.74	GO:0009263	deoxyribonucleotide biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0006264	mitochondrial DNA replication
0.49	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
0.48	GO:0003014	renal system process
0.47	GO:0001822	kidney development
0.45	GO:0009200	deoxyribonucleoside triphosphate metabolic process
0.45	GO:0006974	cellular response to DNA damage stimulus
0.44	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.43	GO:0006979	response to oxidative stress

0.54	GO:0016491	oxidoreductase activity
0.48	GO:0046872	metal ion binding
0.34	GO:0043130	ubiquitin binding
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0016874	ligase activity

0.45	GO:0005829	cytosol
0.43	GO:0005654	nucleoplasm
0.41	GO:1990204	oxidoreductase complex
0.40	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.54	EC:1	GO:0016491
0.34	KEGG:R03876	GO:0004842

tr|Q7ZYW7|Q7ZYW7_DANRE
ATP synthase, H+-transporting, mitochondrial Fo complex, subunit C3 (subunit 9), genome duplicate a
Search

0.87	ATP synthase lipid-binding protein, mitochondrial

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.38	GO:0045471	response to ethanol
0.36	GO:0042407	cristae formation
0.35	GO:0006839	mitochondrial transport
0.34	GO:0046907	intracellular transport
0.34	GO:0007568	aging
0.33	GO:0055114	oxidation-reduction process

0.71	GO:0008289	lipid binding
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.44	GO:0019829	cation-transporting ATPase activity
0.44	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.36	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.35	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.33	GO:0005515	protein binding

0.72	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.46	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.34	GO:0005741	mitochondrial outer membrane
0.30	GO:0016021	integral component of membrane

0.36

EC:1.1.1.42

GO:0004450

sp|Q7ZYX1|AKTIP_DANRE
AKT-interacting protein
Search

AKTIP

0.96	AKT-interacting protein homolog A

0.84	GO:0045022	early endosome to late endosome transport
0.83	GO:0008333	endosome to lysosome transport
0.81	GO:0007032	endosome organization
0.81	GO:0007040	lysosome organization
0.77	GO:0032092	positive regulation of protein binding
0.70	GO:0001934	positive regulation of protein phosphorylation
0.56	GO:0016567	protein ubiquitination
0.54	GO:0006915	apoptotic process
0.48	GO:0015031	protein transport

0.60	GO:0031625	ubiquitin protein ligase binding
0.58	GO:0061630	ubiquitin protein ligase activity

0.85	GO:0070695	FHF complex
0.78	GO:0030897	HOPS complex
0.66	GO:0005829	cytosol
0.54	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q7ZYX7|Q7ZYX7_DANRE
Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog)
Search

PSMD7

0.70	Eukaryotic translation initiation factor 3 subunit F

0.46	GO:0021551	central nervous system morphogenesis
0.45	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.45	GO:1904888	cranial skeletal system development
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia

0.49	GO:0042803	protein homodimerization activity
0.34	GO:0003743	translation initiation factor activity

0.81	GO:0005838	proteasome regulatory particle
0.47	GO:0005654	nucleoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|Q7ZYY0|Q7ZYY0_DANRE
Acyl-CoA dehydrogenase family, member 8
Search

ACAD8

0.89	Isobutyryl-CoA dehydrogenaseserine-threonine

0.60	GO:0006629	lipid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.38	GO:0006574	valine catabolic process
0.33	GO:0035335	peptidyl-tyrosine dephosphorylation
0.33	GO:0006351	transcription, DNA-templated
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.74	GO:0003995	acyl-CoA dehydrogenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.33	GO:0004725	protein tyrosine phosphatase activity

0.35	GO:0005739	mitochondrion
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

0.74

EC:1.3.99.3

GO:0003995

sp|Q7ZYY4|FAM3C_DANRE
Protein FAM3C
Search

0.41	GO:0046676	negative regulation of insulin secretion
0.40	GO:0007275	multicellular organism development
0.39	GO:1905035	negative regulation of antifungal innate immune response
0.38	GO:0019732	antifungal humoral response
0.37	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.36	GO:0002576	platelet degranulation
0.35	GO:0006098	pentose-phosphate shunt
0.35	GO:0006006	glucose metabolic process
0.35	GO:0010469	regulation of receptor activity
0.33	GO:0055114	oxidation-reduction process

0.36	GO:0004345	glucose-6-phosphate dehydrogenase activity
0.35	GO:0005125	cytokine activity
0.35	GO:0050661	NADP binding

0.53	GO:0005615	extracellular space
0.52	GO:0005794	Golgi apparatus
0.38	GO:0031410	cytoplasmic vesicle
0.37	GO:1903561	extracellular vesicle
0.36	GO:0031983	vesicle lumen
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:1.1.1.49

GO:0004345

sp|Q7ZYZ6|DLGP1_DANRE
Disks large-associated protein 1
Search

0.91	Discs, large (Drosophila) homolog-associated protein 1b

0.78	GO:0098916	anterograde trans-synaptic signaling
0.40	GO:0006461	protein complex assembly

0.42

GO:0019904

protein domain specific binding

0.76

GO:0045202

synapse

sp|Q7ZYZ7|PCGF1_DANRE
Polycomb group RING finger protein 1
Search

PCGF1

0.97	Polycomb group RING finger protein 1

0.83	GO:0036353	histone H2A-K119 monoubiquitination
0.50	GO:0045892	negative regulation of transcription, DNA-templated
0.42	GO:0007568	aging
0.41	GO:0006351	transcription, DNA-templated
0.39	GO:0048589	developmental growth
0.36	GO:0006357	regulation of transcription by RNA polymerase II

0.72	GO:0008022	protein C-terminus binding
0.40	GO:0046872	metal ion binding
0.37	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.37	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding

0.82	GO:0031519	PcG protein complex
0.61	GO:0005654	nucleoplasm
0.54	GO:0000152	nuclear ubiquitin ligase complex

tr|Q7ZYZ9|Q7ZYZ9_DANRE
A disintegrin and metalloproteinase domain 8a
Search

0.81	Disintegrin and metalloproteinase domain-containing protein 8

0.79	GO:0007229	integrin-mediated signaling pathway
0.60	GO:0006508	proteolysis
0.40	GO:2000391	positive regulation of neutrophil extravasation
0.40	GO:0051044	positive regulation of membrane protein ectodomain proteolysis
0.39	GO:0071456	cellular response to hypoxia
0.38	GO:2000399	negative regulation of thymocyte aggregation
0.38	GO:0006954	inflammatory response
0.38	GO:2000415	positive regulation of fibronectin-dependent thymocyte migration
0.37	GO:2000309	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production
0.37	GO:2000418	positive regulation of eosinophil migration

0.70	GO:0004222	metalloendopeptidase activity
0.53	GO:0046872	metal ion binding
0.40	GO:0002020	protease binding
0.38	GO:0050839	cell adhesion molecule binding
0.35	GO:0032403	protein complex binding
0.35	GO:0005102	receptor binding
0.35	GO:0017124	SH3 domain binding
0.35	GO:0090729	toxin activity

0.41	GO:0032127	dense core granule membrane
0.40	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex
0.40	GO:0032010	phagolysosome
0.40	GO:0070820	tertiary granule
0.39	GO:0042581	specific granule
0.39	GO:0002102	podosome
0.37	GO:0071133	alpha9-beta1 integrin-ADAM8 complex
0.37	GO:0009986	cell surface
0.36	GO:0005887	integral component of plasma membrane
0.34	GO:0005794	Golgi apparatus

0.70

GO:0004222

sp|Q7ZZ00|ZN511_DANRE
Zinc finger protein 511
Search

ZNF511

0.84	Polyamine oxidase

0.36	GO:0007020	microtubule nucleation
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.34	GO:0016579	protein deubiquitination
0.33	GO:0006605	protein targeting
0.33	GO:0071806	protein transmembrane transport
0.32	GO:0043043	peptide biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.36	GO:0043015	gamma-tubulin binding
0.35	GO:0046872	metal ion binding
0.34	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.34	GO:0004222	metalloendopeptidase activity
0.33	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
0.32	GO:0003735	structural constituent of ribosome

0.36	GO:0000922	spindle pole
0.36	GO:0005815	microtubule organizing center
0.35	GO:0005634	nucleus
0.34	GO:0005874	microtubule
0.32	GO:0005737	cytoplasm
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.34

GO:0004222

sp|Q7ZZ03|FUCM_DANRE
Fucose mutarotase
Search

FUOM

0.59	L-fucose mutarotase

0.66	GO:0005996	monosaccharide metabolic process
0.49	GO:0060180	female mating behavior
0.47	GO:0045665	negative regulation of neuron differentiation
0.46	GO:0036065	fucosylation

0.73	GO:0048029	monosaccharide binding
0.61	GO:0016853	isomerase activity

0.33

GO:0005829

cytosol

0.61

GO:0016853

tr|Q7ZZ04|Q7ZZ04_DANRE
Enoyl CoA hydratase, short chain, 1, mitochondrial
Search

ECHS1

0.38	Enoyl-CoA hydrataseserine-threonine

0.51	GO:0006635	fatty acid beta-oxidation
0.32	GO:0005996	monosaccharide metabolic process

0.53	GO:0004300	enoyl-CoA hydratase activity
0.36	GO:0016508	long-chain-enoyl-CoA hydratase activity
0.33	GO:0005515	protein binding
0.33	GO:0048029	monosaccharide binding
0.32	GO:0016853	isomerase activity

0.44	GO:0005739	mitochondrion
0.36	GO:0043233	organelle lumen
0.36	GO:0070062	extracellular exosome
0.35	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

0.53

EC:4.2.1.17

GO:0004300

sp|Q7ZZ25|ATD1A_DANRE
ATPase family AAA domain-containing protein 1-A
Search

0.87	ATPase family AAA domain-containing protein 1-A

0.54	GO:0051967	negative regulation of synaptic transmission, glutamatergic
0.53	GO:0002092	positive regulation of receptor internalization
0.51	GO:0007613	memory
0.51	GO:0007612	learning

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0016887	ATPase activity
0.34	GO:0005515	protein binding

0.51	GO:0045211	postsynaptic membrane
0.42	GO:0005739	mitochondrion
0.40	GO:0005634	nucleus
0.40	GO:0005777	peroxisome
0.40	GO:0030054	cell junction
0.36	GO:0031903	microbody membrane
0.30	GO:0016021	integral component of membrane

0.44

GO:0016887

tr|Q7ZZ26|Q7ZZ26_DANRE
Galectin
Search

LGALSL

0.68

Galectin

0.36	GO:0015844	monoamine transport
0.36	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.33	GO:0006468	protein phosphorylation

0.69	GO:0030246	carbohydrate binding
0.36	GO:0008022	protein C-terminus binding
0.35	GO:0019904	protein domain specific binding
0.33	GO:0019899	enzyme binding

0.37	GO:0005622	intracellular
0.36	GO:0042734	presynaptic membrane
0.33	GO:0012505	endomembrane system
0.33	GO:0043227	membrane-bounded organelle

tr|Q7ZZ27|Q7ZZ27_DANRE
SERTA domain-containing 2b
Search

SERTAD2B

0.88	SERTA domain-containing protein 2

0.81	GO:0030308	negative regulation of cell growth
0.71	GO:0045893	positive regulation of transcription, DNA-templated
0.38	GO:0051301	cell division
0.38	GO:2000483	negative regulation of interleukin-8 secretion
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:0042494	detection of bacterial lipoprotein
0.37	GO:0050830	defense response to Gram-positive bacterium
0.37	GO:0050829	defense response to Gram-negative bacterium
0.35	GO:0006898	receptor-mediated endocytosis

0.77	GO:0003713	transcription coactivator activity
0.38	GO:0005515	protein binding
0.37	GO:0050840	extracellular matrix binding
0.36	GO:0005044	scavenger receptor activity

0.67	GO:0005654	nucleoplasm
0.66	GO:0005829	cytosol
0.36	GO:0031012	extracellular matrix
0.35	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

tr|Q7ZZ32|Q7ZZ32_DANRE
5-hydroxytryptamine (Serotonin) receptor 5A like
Search

HTR5A

0.97	5-hydroxytryptamine (Serotonin) receptor 5A, G protein-coupled

0.82	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.55	GO:0019933	cAMP-mediated signaling
0.48	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.40	GO:0032355	response to estradiol
0.40	GO:0021766	hippocampus development

0.83	GO:0099589	serotonin receptor activity
0.79	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.79	GO:0008227	G-protein coupled amine receptor activity
0.50	GO:0051378	serotonin binding
0.33	GO:0008144	drug binding

0.61	GO:0005887	integral component of plasma membrane
0.40	GO:0043204	perikaryon
0.39	GO:0005791	rough endoplasmic reticulum
0.39	GO:0030425	dendrite
0.37	GO:0005794	Golgi apparatus

tr|Q7ZZ36|Q7ZZ36_DANRE
Breast cancer metastasis suppressor 1
Search

BRMS1

0.94	Breast cancer metastasis-suppressor 1 like

0.70	GO:0016575	histone deacetylation
0.68	GO:0000122	negative regulation of transcription by RNA polymerase II
0.49	GO:2000210	positive regulation of anoikis
0.48	GO:0090312	positive regulation of protein deacetylation
0.47	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.44	GO:0006915	apoptotic process
0.44	GO:0006351	transcription, DNA-templated
0.43	GO:0040008	regulation of growth

0.74	GO:0042826	histone deacetylase binding
0.70	GO:0004407	histone deacetylase activity
0.45	GO:0051059	NF-kappaB binding

0.73	GO:0070822	Sin3-type complex
0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.70

EC:3.5.1.98

GO:0004407

tr|Q7ZZ37|Q7ZZ37_DANRE
Ppp1r14b protein
Search

PPP1R14B

0.96	Protein phosphatase 1 regulatory inhibitor subunit 14B

0.73	GO:0042325	regulation of phosphorylation
0.46	GO:0045087	innate immune response
0.46	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.34	GO:0006468	protein phosphorylation
0.34	GO:0007283	spermatogenesis
0.33	GO:0007165	signal transduction
0.33	GO:0006915	apoptotic process

0.46	GO:0004864	protein phosphatase inhibitor activity
0.34	GO:0004672	protein kinase activity
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046872	metal ion binding
0.33	GO:0004871	signal transducer activity

0.49	GO:0005737	cytoplasm
0.34	GO:0005801	cis-Golgi network
0.34	GO:0012505	endomembrane system
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|Q7ZZ38|Q7ZZ38_DANRE
Phosphoinositide phospholipase C
Search

0.52	Phosphoinositide phospholipase C

0.72	GO:0016042	lipid catabolic process
0.62	GO:0035556	intracellular signal transduction
0.56	GO:0032501	multicellular organismal process
0.53	GO:0060322	head development
0.51	GO:0090281	negative regulation of calcium ion import
0.50	GO:0051726	regulation of cell cycle
0.49	GO:1904888	cranial skeletal system development
0.48	GO:0061448	connective tissue development
0.47	GO:0048729	tissue morphogenesis
0.46	GO:0065008	regulation of biological quality

0.81	GO:0004435	phosphatidylinositol phospholipase C activity
0.67	GO:0005509	calcium ion binding
0.63	GO:0004871	signal transducer activity
0.47	GO:0005516	calmodulin binding
0.47	GO:0045296	cadherin binding
0.37	GO:0005521	lamin binding
0.37	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.36	GO:0005096	GTPase activator activity
0.35	GO:0019899	enzyme binding

0.48	GO:0005634	nucleus
0.43	GO:0070013	intracellular organelle lumen
0.40	GO:0043234	protein complex
0.40	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm
0.36	GO:0043209	myelin sheath
0.35	GO:0005694	chromosome

0.81	EC:3.1.4.11	GO:0004435
0.81	KEGG:R03435	GO:0004435

tr|Q7ZZ64|Q7ZZ64_DANRE
SI:dZ75P05.3.2 (Novel protein)
Search

tr|Q7ZZA3|Q7ZZA3_DANRE
Peptidylprolyl isomerase
Search

FKBP11

0.43	Peptidyl-prolyl cis-trans isomerase FKBP11

0.78	GO:0061077	chaperone-mediated protein folding
0.72	GO:0000413	protein peptidyl-prolyl isomerization

0.85	GO:0005528	FK506 binding
0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.49	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.72

GO:0003755

tr|Q7ZZB1|Q7ZZB1_DANRE
Sorting nexin
Search

SNX9B

0.70	Sorting nexin

0.81	GO:0000281	mitotic cytokinesis
0.71	GO:0006897	endocytosis
0.69	GO:0006886	intracellular protein transport

0.77

GO:0035091

phosphatidylinositol binding

0.68

GO:0030659

cytoplasmic vesicle membrane

sp|Q7ZZC6|CENPM_DANRE
Centromere protein M
Search

CENPM

0.97	Proliferation-associated nuclear element

0.41	GO:0034080	CENP-A containing nucleosome assembly
0.39	GO:0007062	sister chromatid cohesion

0.66	GO:0005829	cytosol
0.52	GO:0000775	chromosome, centromeric region
0.45	GO:0005634	nucleus
0.45	GO:0000793	condensed chromosome
0.39	GO:0043234	protein complex
0.37	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

tr|Q7ZZJ7|Q7ZZJ7_DANRE
Anion exchange protein
Search

0.63	Anion exchange protein (Fragment)

0.68	GO:0015698	inorganic anion transport
0.68	GO:0098656	anion transmembrane transport
0.53	GO:0015701	bicarbonate transport
0.48	GO:0035162	embryonic hemopoiesis
0.47	GO:0030218	erythrocyte differentiation
0.44	GO:0051453	regulation of intracellular pH
0.44	GO:0070509	calcium ion import
0.43	GO:0042891	antibiotic transport
0.42	GO:0035725	sodium ion transmembrane transport
0.34	GO:0010037	response to carbon dioxide

0.82	GO:0005452	inorganic anion exchanger activity
0.53	GO:0015106	bicarbonate transmembrane transporter activity
0.51	GO:0015301	anion:anion antiporter activity
0.43	GO:0042895	antibiotic transmembrane transporter activity
0.43	GO:0030506	ankyrin binding
0.42	GO:0015296	anion:cation symporter activity
0.41	GO:0015081	sodium ion transmembrane transporter activity
0.40	GO:0015108	chloride transmembrane transporter activity
0.40	GO:0042803	protein homodimerization activity
0.34	GO:0043495	protein membrane anchor

0.42	GO:0005887	integral component of plasma membrane
0.42	GO:0016323	basolateral plasma membrane
0.41	GO:0030863	cortical cytoskeleton
0.36	GO:0030018	Z disc
0.35	GO:0072562	blood microparticle
0.34	GO:0070062	extracellular exosome
0.34	GO:0016324	apical plasma membrane
0.34	GO:0014704	intercalated disc
0.33	GO:0005634	nucleus
0.33	GO:0009986	cell surface

sp|Q7ZZY8|UTS2B_DANRE
Prepro-urotensin II-beta
Search

0.96	Prepro-urotensin II-beta

0.83	GO:0008217	regulation of blood pressure
0.83	GO:0097746	regulation of blood vessel diameter
0.76	GO:0010469	regulation of receptor activity

0.79

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

tr|Q7ZZZ4|Q7ZZZ4_DANRE
HIG1 hypoxia-inducible domain family, member 1A
Search

HIGD1A

0.96	Hypoxia-inducible gene 1

0.49	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.48	GO:0071456	cellular response to hypoxia
0.48	GO:0042149	cellular response to glucose starvation
0.46	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.34	GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress
0.34	GO:0055114	oxidation-reduction process
0.34	GO:0032259	methylation

0.34

GO:0008168

methyltransferase activity

0.41	GO:0005634	nucleus
0.41	GO:0005739	mitochondrion
0.41	GO:0019866	organelle inner membrane
0.37	GO:0043233	organelle lumen
0.35	GO:0070469	respiratory chain
0.35	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.34

GO:0008168

tr|Q800A1|Q800A1_DANRE
Parvalbumin 9
Search

0.92	Parvalbumin beta

0.34

GO:0023052

signaling

0.70

GO:0005509

calcium ion binding

tr|Q800E7|Q800E7_DANRE
Phosphodiesterase
Search

PDE6A

0.54	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha

0.61	GO:0007165	signal transduction
0.58	GO:0051480	regulation of cytosolic calcium ion concentration
0.57	GO:0007601	visual perception
0.54	GO:0046037	GMP metabolic process
0.47	GO:0060041	retina development in camera-type eye
0.45	GO:0009583	detection of light stimulus
0.37	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.36	GO:0045494	photoreceptor cell maintenance
0.36	GO:0071482	cellular response to light stimulus
0.35	GO:0198738	cell-cell signaling by wnt

0.80	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.54	GO:0046872	metal ion binding

0.48	GO:0001750	photoreceptor outer segment
0.39	GO:0060170	ciliary membrane

0.80

EC:3.1.4.17

GO:0004114

sp|Q800G5|MXE_DANRE
Interferon-induced GTP-binding protein MxE
Search

0.75	Myxovirus resistance protein 1

0.38	GO:0051607	defense response to virus
0.38	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission
0.38	GO:0035455	response to interferon-alpha
0.37	GO:0000266	mitochondrial fission
0.37	GO:0046822	regulation of nucleocytoplasmic transport
0.36	GO:0045087	innate immune response
0.36	GO:0051726	regulation of cell cycle
0.35	GO:0061025	membrane fusion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0008017	microtubule binding

0.36	GO:0005643	nuclear pore
0.34	GO:0031966	mitochondrial membrane

sp|Q800G8|MXB_DANRE
Interferon-induced GTP-binding protein MxB
Search

0.75	Interferon-induced GTP-binding protein MxB

0.44	GO:0034340	response to type I interferon
0.44	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission
0.44	GO:0009615	response to virus
0.43	GO:0000266	mitochondrial fission
0.42	GO:0002252	immune effector process
0.42	GO:0098542	defense response to other organism
0.41	GO:0045071	negative regulation of viral genome replication
0.39	GO:0061025	membrane fusion
0.38	GO:1901253	negative regulation of intracellular transport of viral material
0.38	GO:0035455	response to interferon-alpha

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0008017	microtubule binding
0.37	GO:0042802	identical protein binding

0.41	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0031967	organelle envelope
0.38	GO:0031090	organelle membrane
0.38	GO:0012505	endomembrane system
0.38	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0005829	cytosol
0.36	GO:0005615	extracellular space
0.35	GO:0031984	organelle subcompartment
0.33	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

tr|Q800H6|Q800H6_DANRE
Matrin 3-like 1.1
Search

0.40	GO:0003170	heart valve development
0.39	GO:0003281	ventricular septum development
0.36	GO:0002218	activation of innate immune response
0.36	GO:0045087	innate immune response
0.35	GO:0010608	posttranscriptional regulation of gene expression
0.32	GO:0008380	RNA splicing
0.32	GO:0006351	transcription, DNA-templated

0.60	GO:0008270	zinc ion binding
0.58	GO:0003723	RNA binding
0.35	GO:0042802	identical protein binding
0.32	GO:0005198	structural molecule activity
0.32	GO:0004386	helicase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.57	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0012505	endomembrane system
0.32	GO:0031090	organelle membrane
0.32	GO:0031975	envelope
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q800H9|H6ST2_DANRE
Heparan-sulfate 6-O-sulfotransferase 2
Search

0.76	Heparan-sulfate 6-O-sulfotransferase

0.57	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification
0.49	GO:0001525	angiogenesis
0.48	GO:0035295	tube development
0.47	GO:0048568	embryonic organ development
0.46	GO:0048666	neuron development
0.44	GO:0061138	morphogenesis of a branching epithelium
0.44	GO:0060541	respiratory system development
0.44	GO:0048592	eye morphogenesis
0.43	GO:0060674	placenta blood vessel development
0.43	GO:0048598	embryonic morphogenesis

0.78	GO:0008146	sulfotransferase activity
0.35	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding
0.35	GO:0070492	oligosaccharide binding

0.37	GO:0005654	nucleoplasm
0.35	GO:0000139	Golgi membrane
0.34	GO:0070062	extracellular exosome
0.33	GO:0005887	integral component of plasma membrane

0.78

GO:0008146

sp|Q800Q5|T7L1B_DANRE
Transcription factor 7-like 1-B
Search

TCF7L1

0.92	T-cell factor-4 variant I

0.84	GO:0060070	canonical Wnt signaling pathway
0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.41	GO:0007275	multicellular organism development
0.40	GO:0010456	cell proliferation in dorsal spinal cord
0.39	GO:0060847	endothelial cell fate specification
0.38	GO:0060322	head development
0.38	GO:0009653	anatomical structure morphogenesis
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:0048318	axial mesoderm development
0.37	GO:2000036	regulation of stem cell population maintenance

0.83	GO:0008013	beta-catenin binding
0.54	GO:0003677	DNA binding
0.44	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0003682	chromatin binding
0.35	GO:0008134	transcription factor binding
0.35	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003779	actin binding

0.61	GO:0005634	nucleus
0.45	GO:0005667	transcription factor complex
0.44	GO:0005829	cytosol
0.44	GO:0043233	organelle lumen
0.40	GO:0044446	intracellular organelle part

tr|Q800U8|Q800U8_DANRE
Ff1d
Search

NR5A2

0.77	Steroidogenic factor 1

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.54	GO:0031016	pancreas development
0.52	GO:0061017	hepatoblast differentiation
0.49	GO:0035272	exocrine system development
0.49	GO:0051216	cartilage development
0.48	GO:0055123	digestive system development

0.79	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.46	GO:0003682	chromatin binding
0.46	GO:0044212	transcription regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding
0.41	GO:0005543	phospholipid binding
0.36	GO:0016301	kinase activity
0.33	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.45	GO:0005667	transcription factor complex
0.39	GO:0044446	intracellular organelle part
0.38	GO:1905369	endopeptidase complex
0.35	GO:0005737	cytoplasm
0.32	GO:0005694	chromosome
0.32	GO:0031974	membrane-enclosed lumen

tr|Q800V7|Q800V7_DANRE
Cardiac troponin C
Search

TNNC1

0.93	Troponin C, slow skeletal and cardiac muscles

0.61	GO:0060048	cardiac muscle contraction
0.59	GO:0032972	regulation of muscle filament sliding speed
0.58	GO:0003231	cardiac ventricle development
0.57	GO:0014883	transition between fast and slow fiber
0.56	GO:0003229	ventricular cardiac muscle tissue development
0.55	GO:0055008	cardiac muscle tissue morphogenesis
0.55	GO:0003206	cardiac chamber morphogenesis
0.51	GO:0043462	regulation of ATPase activity
0.50	GO:0003009	skeletal muscle contraction
0.44	GO:0014823	response to activity

0.69	GO:0005509	calcium ion binding
0.59	GO:0031014	troponin T binding
0.58	GO:0031013	troponin I binding
0.58	GO:0048306	calcium-dependent protein binding
0.53	GO:0051015	actin filament binding
0.50	GO:0042803	protein homodimerization activity

0.58	GO:1990584	cardiac Troponin complex
0.35	GO:0097512	cardiac myofibril
0.33	GO:0005829	cytosol

tr|Q800W7|Q800W7_DANRE
Uroporphyrinogen III synthase
Search

UROS

0.49	Uroporphyrinogen III synthase

0.69	GO:0033014	tetrapyrrole biosynthetic process
0.60	GO:0046502	uroporphyrinogen III metabolic process
0.50	GO:0042168	heme metabolic process
0.49	GO:0046148	pigment biosynthetic process
0.46	GO:0051188	cofactor biosynthetic process
0.45	GO:0046394	carboxylic acid biosynthetic process
0.42	GO:0070541	response to platinum ion
0.42	GO:0071418	cellular response to amine stimulus
0.41	GO:0071243	cellular response to arsenic-containing substance
0.38	GO:0046677	response to antibiotic

0.79	GO:0004852	uroporphyrinogen-III synthase activity
0.35	GO:0048037	cofactor binding
0.32	GO:0004222	metalloendopeptidase activity
0.32	GO:0008270	zinc ion binding

0.43	GO:0005739	mitochondrion
0.37	GO:0005829	cytosol
0.32	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

0.79	EC:4.2.1.75	GO:0004852
0.79	KEGG:R03165	GO:0004852

sp|Q801E0|VAX1_DANRE
Ventral anterior homeobox 1
Search

VAX1

0.96	Ventral anterior homeobox 1

0.75	GO:0007411	axon guidance
0.74	GO:0007420	brain development
0.63	GO:0001654	eye development
0.58	GO:0007406	negative regulation of neuroblast proliferation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0035914	skeletal muscle cell differentiation
0.56	GO:0060021	palate development
0.56	GO:0010468	regulation of gene expression
0.56	GO:0001764	neuron migration

0.61	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.59	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding
0.56	GO:0031490	chromatin DNA binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.32	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm

sp|Q801E1|VAX2_DANRE
Ventral anterior homeobox 2
Search

VAX2

0.97	Ventral anterior homeobox containing gene 2

0.74	GO:0048048	embryonic eye morphogenesis
0.67	GO:0007601	visual perception
0.67	GO:0007420	brain development
0.67	GO:0007409	axonogenesis
0.64	GO:0006357	regulation of transcription by RNA polymerase II
0.62	GO:0097485	neuron projection guidance
0.60	GO:0043010	camera-type eye development
0.52	GO:0009950	dorsal/ventral axis specification
0.52	GO:0050767	regulation of neurogenesis
0.52	GO:0048523	negative regulation of cellular process

0.62	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding
0.57	GO:0031490	chromatin DNA binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding
0.32	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm

tr|Q801E6|Q801E6_DANRE
Malate dehydrogenase
Search

0.47	Malate dehydrogenase

0.78	GO:0006108	malate metabolic process
0.70	GO:0006099	tricarboxylic acid cycle
0.60	GO:0005975	carbohydrate metabolic process
0.48	GO:0006734	NADH metabolic process
0.46	GO:0006107	oxaloacetate metabolic process
0.33	GO:0044283	small molecule biosynthetic process
0.32	GO:1901576	organic substance biosynthetic process

0.79	GO:0030060	L-malate dehydrogenase activity
0.36	GO:0051287	NAD binding
0.36	GO:0047860	diiodophenylpyruvate reductase activity
0.34	GO:0004470	malic enzyme activity
0.33	GO:0005515	protein binding

0.48	GO:0043209	myelin sheath
0.43	GO:0005739	mitochondrion
0.42	GO:0005829	cytosol
0.36	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

0.79	EC:1.1.1.37	GO:0030060
0.36	KEGG:R03431	GO:0047860

sp|Q801F7|WN10B_DANRE
Protein Wnt-10b
Search

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.52	GO:0009888	tissue development
0.52	GO:0051885	positive regulation of timing of anagen
0.52	GO:0030154	cell differentiation
0.51	GO:0071495	cellular response to endogenous stimulus
0.51	GO:0071310	cellular response to organic substance
0.51	GO:0071107	response to parathyroid hormone
0.51	GO:0042487	regulation of odontogenesis of dentin-containing tooth
0.51	GO:0061430	bone trabecula morphogenesis

0.73	GO:0005102	receptor binding
0.46	GO:0030545	receptor regulator activity
0.35	GO:0005525	GTP binding

0.75	GO:0005578	proteinaceous extracellular matrix
0.46	GO:0005615	extracellular space
0.31	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|Q801G2|MPRAB_DANRE
Membrane progestin receptor alpha-B
Search

0.94	G protein coupled progestin receptor alpha

0.51	GO:0048545	response to steroid hormone
0.49	GO:0071396	cellular response to lipid
0.49	GO:0071407	cellular response to organic cyclic compound
0.49	GO:0009755	hormone-mediated signaling pathway
0.46	GO:0048477	oogenesis
0.45	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.44	GO:0000187	activation of MAPK activity
0.44	GO:0071695	anatomical structure maturation
0.44	GO:0048469	cell maturation
0.38	GO:0007275	multicellular organism development

0.53	GO:0005496	steroid binding
0.50	GO:0003707	steroid hormone receptor activity

0.45	GO:0005794	Golgi apparatus
0.44	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q801G3|Q801G3_DANRE
Membrane progestin receptor beta
Search

PAQR8

0.97	G protein coupled progestin receptor beta

0.50	GO:0048545	response to steroid hormone
0.48	GO:0071396	cellular response to lipid
0.48	GO:0071407	cellular response to organic cyclic compound
0.48	GO:0009755	hormone-mediated signaling pathway
0.43	GO:0048477	oogenesis
0.39	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.39	GO:0000187	activation of MAPK activity
0.38	GO:0071695	anatomical structure maturation
0.38	GO:0007275	multicellular organism development
0.38	GO:0048469	cell maturation

0.52	GO:0005496	steroid binding
0.49	GO:0003707	steroid hormone receptor activity

0.47	GO:0005794	Golgi apparatus
0.44	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q801M3|Q801M3_DANRE
Myosin light chain 2 Mlc2a
Search

MYL7

0.89	Myosin light chain, phosphorylatable, fast skeletal muscle b

0.48	GO:0055004	atrial cardiac myofibril assembly
0.47	GO:0055005	ventricular cardiac myofibril assembly
0.46	GO:0060038	cardiac muscle cell proliferation
0.46	GO:0045823	positive regulation of heart contraction
0.45	GO:0045214	sarcomere organization
0.45	GO:0060047	heart contraction
0.39	GO:0001678	cellular glucose homeostasis
0.38	GO:0046835	carbohydrate phosphorylation
0.37	GO:0006757	ATP generation from ADP
0.37	GO:0006090	pyruvate metabolic process

0.70	GO:0005509	calcium ion binding
0.39	GO:0005536	glucose binding
0.38	GO:0004396	hexokinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0003887	DNA-directed DNA polymerase activity
0.32	GO:0003677	DNA binding

0.50	GO:0031672	A band
0.50	GO:0043197	dendritic spine
0.38	GO:0016459	myosin complex
0.34	GO:0036379	myofilament
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.38

EC:2.7.1.1

GO:0004396

tr|Q801U3|Q801U3_DANRE
Serine/arginine-rich-splicing factor 3a
Search

SRSF3

0.95	Serine and arginine rich splicing factor 3

0.51	GO:1990830	cellular response to leukemia inhibitory factor
0.50	GO:0048024	regulation of mRNA splicing, via spliceosome
0.36	GO:0051028	mRNA transport
0.36	GO:0008380	RNA splicing
0.35	GO:0006397	mRNA processing
0.35	GO:0008286	insulin receptor signaling pathway
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0031123	RNA 3'-end processing
0.34	GO:0007050	cell cycle arrest

0.59	GO:0003723	RNA binding
0.54	GO:0043274	phospholipase binding
0.34	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0016607	nuclear speck
0.33	GO:0005737	cytoplasm
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|Q801U5|Q801U5_DANRE
Peptidylprolyl isomerase
Search

FKBP5

0.47	Peptidyl-prolyl cis-trans isomerase FKBP5

0.79	GO:0061077	chaperone-mediated protein folding
0.72	GO:0000413	protein peptidyl-prolyl isomerization

0.85	GO:0005528	FK506 binding
0.78	GO:0031072	heat shock protein binding
0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.60	GO:0070062	extracellular exosome
0.56	GO:0005634	nucleus
0.53	GO:0005829	cytosol
0.52	GO:0031974	membrane-enclosed lumen
0.46	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.72

GO:0003755

tr|Q801U9|Q801U9_DANRE
Synaptoporin
Search

SYNPR

0.95	Synaptophysin IIa

0.42	GO:0048168	regulation of neuronal synaptic plasticity
0.33	GO:0006874	cellular calcium ion homeostasis
0.32	GO:0006508	proteolysis

0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0005515	protein binding
0.33	GO:0004252	serine-type endopeptidase activity
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.82	GO:0008021	synaptic vesicle
0.48	GO:0099501	exocytic vesicle membrane
0.45	GO:0031301	integral component of organelle membrane
0.36	GO:0043005	neuron projection
0.36	GO:0030054	cell junction
0.33	GO:0030141	secretory granule

0.33

EC:3.4.21

GO:0004252

tr|Q801V1|Q801V1_DANRE
Lysosomal associated protein transmembrane 4 beta
Search

LAPTM4B

0.97	Lysosomal associated protein transmembrane 4 beta

0.54	GO:1905671	regulation of lysosome organization
0.54	GO:1905166	negative regulation of lysosomal protein catabolic process
0.54	GO:0097213	regulation of lysosomal membrane permeability
0.53	GO:0032911	negative regulation of transforming growth factor beta1 production
0.50	GO:0007032	endosome organization
0.49	GO:0032509	endosome transport via multivesicular body sorting pathway
0.34	GO:0045766	positive regulation of angiogenesis
0.34	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.34	GO:0043066	negative regulation of apoptotic process

0.52	GO:0097001	ceramide binding
0.49	GO:1902936	phosphatidylinositol bisphosphate binding
0.47	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0019900	kinase binding

0.53	GO:0097487	multivesicular body, internal vesicle
0.52	GO:0032585	multivesicular body membrane
0.49	GO:0005765	lysosomal membrane
0.48	GO:0005769	early endosome
0.44	GO:0042995	cell projection
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q801V3|Q801V3_DANRE
Antizyme inhibitor 1b
Search

0.97	Antizyme inhibitor 1

0.73	GO:0006596	polyamine biosynthetic process
0.70	GO:0043085	positive regulation of catalytic activity
0.50	GO:1902269	positive regulation of polyamine transmembrane transport
0.47	GO:0042177	negative regulation of protein catabolic process
0.43	GO:0009445	putrescine metabolic process
0.42	GO:0006591	ornithine metabolic process
0.35	GO:0006521	regulation of cellular amino acid metabolic process

0.85	GO:0042978	ornithine decarboxylase activator activity
0.43	GO:0004586	ornithine decarboxylase activity
0.33	GO:0005515	protein binding

0.41	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

0.43	EC:4.1.1.17	GO:0004586
0.43	KEGG:R00670	GO:0004586

tr|Q801Y4|Q801Y4_DANRE
Cellular retinoic acid binding protein 2, a
Search

CRABP2

0.97	Cellular retinoic acid binding protein type II

0.72	GO:0048385	regulation of retinoic acid receptor signaling pathway
0.70	GO:0042573	retinoic acid metabolic process
0.64	GO:0042363	fat-soluble vitamin catabolic process
0.64	GO:0016103	diterpenoid catabolic process
0.54	GO:0048672	positive regulation of collateral sprouting
0.54	GO:0072329	monocarboxylic acid catabolic process
0.53	GO:0035115	embryonic forelimb morphogenesis
0.49	GO:0021575	hindbrain morphogenesis
0.34	GO:0016102	diterpenoid biosynthetic process
0.34	GO:0008544	epidermis development

0.80	GO:0001972	retinoic acid binding
0.45	GO:0019841	retinol binding
0.44	GO:0016918	retinal binding
0.36	GO:0019215	intermediate filament binding
0.34	GO:0030332	cyclin binding
0.33	GO:0005198	structural molecule activity

0.50	GO:0005634	nucleus
0.46	GO:0005829	cytosol
0.45	GO:0031974	membrane-enclosed lumen
0.41	GO:0044446	intracellular organelle part
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0070062	extracellular exosome
0.35	GO:0045111	intermediate filament cytoskeleton
0.34	GO:0099512	supramolecular fiber

tr|Q802C8|Q802C8_DANRE
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
Search

SMARCD1

0.93	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

0.50	GO:0048096	chromatin-mediated maintenance of transcription
0.49	GO:0031498	chromatin disassembly
0.49	GO:0032986	protein-DNA complex disassembly
0.47	GO:0060216	definitive hemopoiesis
0.46	GO:0034728	nucleosome organization
0.46	GO:0021510	spinal cord development
0.46	GO:0002244	hematopoietic progenitor cell differentiation
0.46	GO:0061053	somite development
0.39	GO:0071398	cellular response to fatty acid
0.38	GO:0055007	cardiac muscle cell differentiation

0.47	GO:0032947	protein complex scaffold activity
0.37	GO:0003682	chromatin binding
0.37	GO:0005102	receptor binding
0.35	GO:0003713	transcription coactivator activity

0.82	GO:0071565	nBAF complex
0.82	GO:0071564	npBAF complex
0.79	GO:0016514	SWI/SNF complex
0.43	GO:0005654	nucleoplasm

tr|Q802C9|Q802C9_DANRE
Eukaryotic translation initiation factor 4A, isoform 1A
Search

EIF4A1

0.87	Eukaryotic initiation factor 4A-II

0.72	GO:0006413	translational initiation
0.49	GO:1900260	negative regulation of RNA-directed 5'-3' RNA polymerase activity
0.49	GO:0010501	RNA secondary structure unwinding
0.46	GO:1990823	response to leukemia inhibitory factor
0.45	GO:0071345	cellular response to cytokine stimulus
0.39	GO:0010468	regulation of gene expression
0.35	GO:0006401	RNA catabolic process
0.35	GO:0016926	protein desumoylation
0.34	GO:0016071	mRNA metabolic process
0.34	GO:0016032	viral process

0.78	GO:0004004	ATP-dependent RNA helicase activity
0.72	GO:0003743	translation initiation factor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0003725	double-stranded RNA binding
0.34	GO:0005515	protein binding
0.34	GO:0000339	RNA cap binding
0.34	GO:0003729	mRNA binding
0.33	GO:0008234	cysteine-type peptidase activity

0.45	GO:0005730	nucleolus
0.44	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0016281	eukaryotic translation initiation factor 4F complex
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.34	GO:0071339	MLL1 complex
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008234

sp|Q802D3|XPO4_DANRE
Exportin-4
Search

XPO4

0.92	Exportin-4

0.82	GO:0046827	positive regulation of protein export from nucleus
0.64	GO:0006611	protein export from nucleus

0.66	GO:0005049	nuclear export signal receptor activity
0.61	GO:0008536	Ran GTPase binding

0.67	GO:0005654	nucleoplasm
0.65	GO:0005829	cytosol
0.59	GO:0005643	nuclear pore

sp|Q802F2|SELTA_DANRE
Selenoprotein T1a
Search

SELENOT

0.96	Selenoprotein T

0.60	GO:0035773	insulin secretion involved in cellular response to glucose stimulus
0.56	GO:0031016	pancreas development
0.49	GO:0045454	cell redox homeostasis
0.44	GO:0060124	positive regulation of growth hormone secretion
0.42	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.41	GO:0098869	cellular oxidant detoxification
0.36	GO:0055114	oxidation-reduction process
0.35	GO:0001514	selenocysteine incorporation

0.43	GO:0004791	thioredoxin-disulfide reductase activity
0.35	GO:0008430	selenium binding
0.34	GO:0005201	extracellular matrix structural constituent

0.50	GO:0005783	endoplasmic reticulum
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.40	GO:0031984	organelle subcompartment
0.34	GO:0005604	basement membrane
0.33	GO:0005581	collagen trimer
0.30	GO:0031224	intrinsic component of membrane

0.43	EC:1.8.1.9	GO:0004791
0.43	KEGG:R02016	GO:0004791

sp|Q802F3|SEP15_DANRE
Selenoprotein F
Search

SELENOF

0.90	15 kDa selenoprotein (inferred by orthology to a zebrafish protein)

0.64	GO:0051084	'de novo' posttranslational protein folding
0.52	GO:0035092	sperm chromatin condensation
0.45	GO:0098869	cellular oxidant detoxification

0.61	GO:0008430	selenium binding
0.49	GO:0008379	thioredoxin peroxidase activity
0.47	GO:0005515	protein binding

0.84	GO:0005788	endoplasmic reticulum lumen
0.57	GO:0070062	extracellular exosome

0.49

EC:1.11.1

GO:0008379

sp|Q802G6|MSB1A_DANRE
Methionine-R-sulfoxide reductase B1-A
Search

MSRB1

0.96	LOW QUALITY PROTEIN: methionine-R-sulfoxide reductase B1

0.77	GO:0030091	protein repair
0.71	GO:0006979	response to oxidative stress
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0030041	actin filament polymerization
0.49	GO:0045087	innate immune response
0.34	GO:0043043	peptide biosynthetic process
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process
0.33	GO:0036211	protein modification process

0.79	GO:0033743	peptide-methionine (R)-S-oxide reductase activity
0.51	GO:0070191	methionine-R-sulfoxide reductase activity
0.47	GO:0003779	actin binding
0.44	GO:0033745	L-methionine-(R)-S-oxide reductase activity
0.41	GO:0008270	zinc ion binding
0.37	GO:0008113	peptide-methionine (S)-S-oxide reductase activity
0.34	GO:0003735	structural constituent of ribosome
0.34	GO:0008146	sulfotransferase activity

0.47	GO:0015629	actin cytoskeleton
0.42	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0044446	intracellular organelle part

0.79	EC:1.8.4 EC:1.8.4.12	GO:0033743
0.79	KEGG:R07607	GO:0033743

sp|Q802G7|SELM_DANRE
Selenoprotein M
Search

SELENOM

0.97	Selenoprotein M

0.87	GO:0035934	corticosterone secretion
0.86	GO:0010269	response to selenium ion
0.84	GO:0060612	adipose tissue development
0.82	GO:0035264	multicellular organism growth
0.73	GO:0042445	hormone metabolic process

0.42

GO:0005515

protein binding

0.70	GO:0005783	endoplasmic reticulum
0.69	GO:0005794	Golgi apparatus
0.55	GO:0048471	perinuclear region of cytoplasm

sp|Q802U2|MIO_DANRE
WD repeat-containing protein mio
Search

MIOS

0.95	Meiosis regulator for oocyte development

0.85	GO:0034198	cellular response to amino acid starvation
0.84	GO:0034629	cellular protein complex localization
0.81	GO:0032008	positive regulation of TOR signaling

0.85	GO:0061700	GATOR2 complex
0.82	GO:0005765	lysosomal membrane
0.75	GO:0030054	cell junction
0.70	GO:0005654	nucleoplasm
0.69	GO:0005829	cytosol

tr|Q802U9|Q802U9_DANRE
3'-phosphoadenosine 5'-phosphosulfate synthase 2
Search

PAPSS2

0.94	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 2

0.77	GO:0000103	sulfate assimilation
0.57	GO:0016310	phosphorylation
0.56	GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process
0.50	GO:0060348	bone development
0.50	GO:0007596	blood coagulation

0.80	GO:0004020	adenylylsulfate kinase activity
0.79	GO:0004781	sulfate adenylyltransferase (ATP) activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0042803	protein homodimerization activity
0.36	GO:0098616	selenate adenylyltransferase (ATP) activity

0.35	GO:0009336	sulfate adenylyltransferase complex (ATP)
0.34	GO:0005829	cytosol

0.80

EC:2.7.1.25

GO:0004020

tr|Q802V0|Q802V0_DANRE
LIM domain binding 3b
Search

0.85	LIM domain-binding protein 3

0.56	GO:0061061	muscle structure development
0.54	GO:0048646	anatomical structure formation involved in morphogenesis
0.51	GO:0061053	somite development
0.51	GO:0035282	segmentation
0.50	GO:0007626	locomotory behavior
0.50	GO:0009952	anterior/posterior pattern specification
0.50	GO:0014706	striated muscle tissue development
0.49	GO:0007507	heart development
0.49	GO:0043009	chordate embryonic development
0.49	GO:0031032	actomyosin structure organization

0.53	GO:0046872	metal ion binding
0.52	GO:0051371	muscle alpha-actinin binding
0.51	GO:0005080	protein kinase C binding

0.50	GO:0030018	Z disc
0.43	GO:0005856	cytoskeleton

tr|Q802V1|Q802V1_DANRE
Synovial sarcoma translocation, chromosome 18 (H. sapiens)
Search

SS18

0.86	Fusion protein SYT-SSX1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.48	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.48	GO:0010468	regulation of gene expression

0.79	GO:0003713	transcription coactivator activity
0.46	GO:0005515	protein binding

0.51

GO:0005634

nucleus

sp|Q802V6|ABH2A_DANRE
Monoacylglycerol lipase ABHD2-A
Search

ABHD2

0.95	Abhydrolase domain-containing protein 2-A

0.59	GO:0048240	sperm capacitation
0.59	GO:0046464	acylglycerol catabolic process
0.57	GO:0032570	response to progesterone
0.57	GO:0007340	acrosome reaction
0.54	GO:0030336	negative regulation of cell migration
0.54	GO:0043401	steroid hormone mediated signaling pathway
0.53	GO:0009611	response to wounding

0.58	GO:0047372	acylglycerol lipase activity
0.55	GO:0042562	hormone binding
0.53	GO:0003707	steroid hormone receptor activity

0.60	GO:0097524	sperm plasma membrane
0.57	GO:0036126	sperm flagellum
0.55	GO:0001669	acrosomal vesicle
0.30	GO:0016021	integral component of membrane

0.58

EC:3.1.1.23

GO:0047372

tr|Q802W1|Q802W1_DANRE
Chic2 protein
Search

CHIC2

0.95	cysteine-rich hydrophobic domain-containing protein 2

0.45

GO:0006893

Golgi to plasma membrane transport

0.33

GO:0005515

protein binding

0.50	GO:0005798	Golgi-associated vesicle
0.47	GO:0005794	Golgi apparatus
0.42	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q802W2|A9A1B_DANRE
Aldehyde dehydrogenase family 9 member A1-B
Search

ALDH9A1

0.50	Betaine aldehyde dehydrogenase

0.53	GO:0055114	oxidation-reduction process
0.50	GO:0042136	neurotransmitter biosynthetic process
0.47	GO:0006081	cellular aldehyde metabolic process
0.40	GO:0045329	carnitine biosynthetic process
0.34	GO:0001889	liver development
0.34	GO:0019285	glycine betaine biosynthetic process from choline
0.34	GO:0001822	kidney development
0.34	GO:0042445	hormone metabolic process

0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.35	GO:0033737	1-pyrroline dehydrogenase activity
0.34	GO:0043176	amine binding
0.34	GO:0042803	protein homodimerization activity
0.33	GO:0051287	NAD binding

0.36	GO:0070062	extracellular exosome
0.35	GO:0005829	cytosol
0.34	GO:0005739	mitochondrion

0.69

GO:0016620

sp|Q802W4|NOL10_DANRE
Nucleolar protein 10
Search

NOL10

0.93	Nucleolar protein 10

0.34

GO:0003723

RNA binding

0.60	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0043232	intracellular non-membrane-bounded organelle
0.43	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|Q802X7|Q802X7_DANRE
Translocating chain-associated membrane protein
Search

TRAM2

0.91	Translocating chain-associated membrane protein 1

0.57	GO:0045184	establishment of protein localization
0.56	GO:0015833	peptide transport
0.55	GO:0032964	collagen biosynthetic process
0.52	GO:0007029	endoplasmic reticulum organization
0.48	GO:0033365	protein localization to organelle
0.48	GO:0072657	protein localization to membrane
0.46	GO:0061024	membrane organization

0.34	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding

0.30

GO:0016020

membrane

tr|Q802Y0|Q802Y0_DANRE
Solute carrier family 35, member E1
Search

SLC35E1

0.96	Solute carrier family 35 member E1

0.46	GO:0005794	Golgi apparatus
0.30	GO:0044425	membrane part

tr|Q802Y1|Q802Y1_DANRE
Serine/arginine-rich-splicing factor 4
Search

SRSF4

0.87	Serine and arginine rich splicing factor 4

0.58	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.41	GO:0045617	negative regulation of keratinocyte differentiation
0.41	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis
0.41	GO:0010837	regulation of keratinocyte proliferation
0.41	GO:0000380	alternative mRNA splicing, via spliceosome
0.40	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.40	GO:0061041	regulation of wound healing
0.40	GO:0006376	mRNA splice site selection
0.39	GO:0032868	response to insulin
0.39	GO:0060548	negative regulation of cell death

0.58	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.54	GO:0016607	nuclear speck
0.30	GO:0016020	membrane

sp|Q802Y8|ZB16A_DANRE
Zinc finger and BTB domain-containing protein 16-A
Search

ZBTB16

0.97	Zinc finger and BTB domain-containing protein 16-A

0.59	GO:0032332	positive regulation of chondrocyte differentiation
0.59	GO:0048133	male germ-line stem cell asymmetric division
0.59	GO:0051138	positive regulation of NK T cell differentiation
0.58	GO:0045600	positive regulation of fat cell differentiation
0.57	GO:0035116	embryonic hindlimb morphogenesis
0.57	GO:0045778	positive regulation of ossification
0.57	GO:0035136	forelimb morphogenesis
0.56	GO:0051216	cartilage development
0.56	GO:0045638	negative regulation of myeloid cell differentiation
0.56	GO:0001823	mesonephros development

0.60	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding
0.58	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.52	GO:0042803	protein homodimerization activity
0.40	GO:0008022	protein C-terminus binding
0.38	GO:0019904	protein domain specific binding
0.35	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0046872	metal ion binding

0.57	GO:0016605	PML body
0.55	GO:0017053	transcriptional repressor complex
0.55	GO:0016607	nuclear speck
0.45	GO:0043234	protein complex
0.37	GO:0005829	cytosol
0.36	GO:0031463	Cul3-RING ubiquitin ligase complex
0.35	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.35

GO:0004842

tr|Q802Z0|Q802Z0_DANRE
YTH N(6)-methyladenosine RNA-binding protein 1
Search

0.90	YTH N(6)-methyladenosine RNA-binding protein 1

0.44

GO:0045948

positive regulation of translational initiation

0.59	GO:0003723	RNA binding
0.42	GO:0043022	ribosome binding
0.32	GO:0005515	protein binding

0.31

GO:0005737

cytoplasm

tr|Q802Z5|Q802Z5_DANRE
Non-POU domain containing, octamer-binding
Search

NONO

0.97	Non-POU domain containing octamer binding

0.53	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
0.52	GO:0042752	regulation of circadian rhythm
0.52	GO:0002218	activation of innate immune response
0.47	GO:0045892	negative regulation of transcription, DNA-templated
0.45	GO:0000398	mRNA splicing, via spliceosome
0.45	GO:0071599	otic vesicle development
0.44	GO:0061053	somite development
0.42	GO:0007417	central nervous system development
0.40	GO:0048511	rhythmic process
0.39	GO:0045087	innate immune response

0.59	GO:0003723	RNA binding
0.52	GO:0001047	core promoter binding
0.51	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.50	GO:0035326	enhancer binding
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0003682	chromatin binding
0.46	GO:0042802	identical protein binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0046872	metal ion binding
0.32	GO:0016787	hydrolase activity

0.56	GO:0042382	paraspeckles
0.51	GO:0016363	nuclear matrix
0.47	GO:0090575	RNA polymerase II transcription factor complex
0.41	GO:0001650	fibrillar center
0.39	GO:0016607	nuclear speck
0.33	GO:0019013	viral nucleocapsid
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.32

GO:0016787

sp|Q803A0|JADE1_DANRE
Protein Jade-1
Search

JADE1

0.93	Bromodomain and PHD finger-containing protein 3

0.67	GO:0043983	histone H4-K12 acetylation
0.66	GO:0043982	histone H4-K8 acetylation
0.66	GO:0043981	histone H4-K5 acetylation
0.63	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.63	GO:0043966	histone H3 acetylation
0.62	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.57	GO:0006366	transcription by RNA polymerase II
0.57	GO:0045944	positive regulation of transcription by RNA polymerase II
0.37	GO:0043984	histone H4-K16 acetylation
0.37	GO:0060395	SMAD protein signal transduction

0.64	GO:0001105	RNA polymerase II transcription coactivator activity
0.54	GO:0046872	metal ion binding
0.36	GO:0061630	ubiquitin protein ligase activity

0.62	GO:0036064	ciliary basal body
0.58	GO:0000123	histone acetyltransferase complex
0.52	GO:0005829	cytosol
0.45	GO:0005886	plasma membrane

sp|Q803A6|MCMBP_DANRE
Mini-chromosome maintenance complex-binding protein
Search

0.56	Putative conserved membrane protein (Fragment)

sp|Q803A7|SPCS_DANRE
O-phosphoseryl-tRNA(Sec) selenium transferase
Search

SEPSECS

0.85	O-phosphoseryl-tRNA(Sec) selenium transferase

0.78	GO:0097056	selenocysteinyl-tRNA(Sec) biosynthetic process
0.56	GO:0043043	peptide biosynthetic process
0.52	GO:0044267	cellular protein metabolic process
0.51	GO:0010467	gene expression
0.50	GO:0034645	cellular macromolecule biosynthetic process
0.48	GO:0006417	regulation of translation
0.34	GO:0016259	selenocysteine metabolic process

0.80	GO:0016785	transferase activity, transferring selenium-containing groups
0.67	GO:0000049	tRNA binding
0.34	GO:0005515	protein binding
0.33	GO:0140101	catalytic activity, acting on a tRNA

0.46	GO:0005737	cytoplasm
0.44	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.80

EC:2.9 EC:2.9.1

GO:0016785

sp|Q803A8|WWOX_DANRE
WW domain-containing oxidoreductase
Search

WWOX

0.87	WW domain-containing oxidoreductase

0.84	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.81	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.80	GO:0097191	extrinsic apoptotic signaling pathway
0.80	GO:0001649	osteoblast differentiation
0.78	GO:0030178	negative regulation of Wnt signaling pathway
0.77	GO:0071560	cellular response to transforming growth factor beta stimulus
0.77	GO:0048705	skeletal system morphogenesis
0.71	GO:0006366	transcription by RNA polymerase II
0.71	GO:0045944	positive regulation of transcription by RNA polymerase II
0.51	GO:0016055	Wnt signaling pathway

0.81	GO:0001105	RNA polymerase II transcription coactivator activity
0.67	GO:0019899	enzyme binding
0.47	GO:0016491	oxidoreductase activity
0.38	GO:0046983	protein dimerization activity
0.36	GO:0050662	coenzyme binding

0.80	GO:0005902	microvillus
0.72	GO:0090575	RNA polymerase II transcription factor complex
0.68	GO:0005794	Golgi apparatus
0.65	GO:0005829	cytosol
0.58	GO:0005739	mitochondrion
0.53	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.47

GO:0016491

tr|Q803B0|Q803B0_DANRE
Heat shock 60 protein 1
Search

HSPD1

0.80	Heat shock protein, mitochondrial

0.76	GO:0042026	protein refolding
0.63	GO:0009409	response to cold
0.52	GO:0002368	B cell cytokine production
0.52	GO:0048291	isotype switching to IgG isotypes
0.52	GO:0042110	T cell activation
0.52	GO:0002842	positive regulation of T cell mediated immune response to tumor cell
0.51	GO:0032727	positive regulation of interferon-alpha production
0.50	GO:0032729	positive regulation of interferon-gamma production
0.50	GO:0043032	positive regulation of macrophage activation
0.49	GO:0032733	positive regulation of interleukin-10 production

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0034186	apolipoprotein A-I binding
0.51	GO:0008035	high-density lipoprotein particle binding
0.48	GO:0002039	p53 binding
0.47	GO:0044183	protein binding involved in protein folding
0.46	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0051087	chaperone binding

0.50	GO:0005759	mitochondrial matrix
0.50	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex
0.49	GO:0046696	lipopolysaccharide receptor complex
0.48	GO:0043209	myelin sheath
0.47	GO:0030141	secretory granule
0.47	GO:0070062	extracellular exosome
0.47	GO:0005905	clathrin-coated pit
0.47	GO:0005769	early endosome
0.45	GO:0030135	coated vesicle
0.45	GO:0005829	cytosol

0.35

GO:0016787

tr|Q803B9|Q803B9_DANRE
DCP2 decapping enzyme homolog (S. cerevisiae)
Search

DCP2

0.91	mRNA decapping enzyme

0.56	GO:0071044	histone mRNA catabolic process
0.55	GO:1904872	regulation of telomerase RNA localization to Cajal body
0.55	GO:0032211	negative regulation of telomere maintenance via telomerase
0.50	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.48	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.37	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.35	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.35	GO:0043488	regulation of mRNA stability

0.71	GO:0030145	manganese ion binding
0.58	GO:0003723	RNA binding
0.58	GO:0050072	m7G(5')pppN diphosphatase activity
0.52	GO:0004534	5'-3' exoribonuclease activity
0.33	GO:0005515	protein binding

0.54	GO:0000932	P-body
0.53	GO:0016442	RISC complex
0.48	GO:0030054	cell junction
0.46	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.58

EC:3.6.1.30

GO:0050072

sp|Q803C1|RNF8_DANRE
E3 ubiquitin-protein ligase rnf8
Search

RNF8

0.93	Ring finger protein 8, E3 ubiquitin protein ligase

0.80	GO:0033522	histone H2A ubiquitination
0.79	GO:0033523	histone H2B ubiquitination
0.77	GO:0045739	positive regulation of DNA repair
0.75	GO:0010212	response to ionizing radiation
0.69	GO:0006302	double-strand break repair
0.62	GO:0070534	protein K63-linked ubiquitination
0.56	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter
0.55	GO:0070936	protein K48-linked ubiquitination
0.52	GO:0051865	protein autoubiquitination
0.50	GO:0051301	cell division

0.72	GO:0042393	histone binding
0.72	GO:0043130	ubiquitin binding
0.70	GO:0003682	chromatin binding
0.67	GO:0004842	ubiquitin-protein transferase activity
0.55	GO:0042803	protein homodimerization activity
0.53	GO:0016874	ligase activity
0.51	GO:0046872	metal ion binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.37	GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity
0.35	GO:0061659	ubiquitin-like protein ligase activity

0.69	GO:0000151	ubiquitin ligase complex
0.58	GO:0000781	chromosome, telomeric region
0.57	GO:0005634	nucleus
0.53	GO:0035861	site of double-strand break
0.47	GO:0030496	midbody
0.45	GO:0005829	cytosol
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

0.53	EC:6	GO:0016874
0.67	KEGG:R03876	GO:0004842

tr|Q803C2|Q803C2_DANRE
Transmembrane protein 33
Search

TMEM33

0.97	Transmembrane protein 33

0.58	GO:1903896	positive regulation of IRE1-mediated unfolded protein response
0.58	GO:1903899	positive regulation of PERK-mediated unfolded protein response
0.57	GO:1903371	regulation of endoplasmic reticulum tubular network organization
0.52	GO:0034976	response to endoplasmic reticulum stress
0.50	GO:0051292	nuclear pore complex assembly
0.50	GO:0071786	endoplasmic reticulum tubular network organization
0.43	GO:0034613	cellular protein localization
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:0098655	cation transmembrane transport

0.47	GO:0017056	structural constituent of nuclear pore
0.34	GO:0005515	protein binding
0.33	GO:0004930	G-protein coupled receptor activity
0.32	GO:0008324	cation transmembrane transporter activity

0.54	GO:0042470	melanosome
0.52	GO:0005635	nuclear envelope
0.51	GO:0030176	integral component of endoplasmic reticulum membrane
0.40	GO:0043234	protein complex
0.36	GO:0070062	extracellular exosome

sp|Q803C3|HDAC3_DANRE
Histone deacetylase 3
Search

HDAC3

0.51	Histone deacetylase

0.80	GO:0016575	histone deacetylation
0.60	GO:1903507	negative regulation of nucleic acid-templated transcription
0.58	GO:0071498	cellular response to fluid shear stress
0.57	GO:0042993	positive regulation of transcription factor import into nucleus
0.56	GO:0046329	negative regulation of JNK cascade
0.54	GO:0051225	spindle assembly
0.54	GO:0032008	positive regulation of TOR signaling
0.53	GO:0031647	regulation of protein stability
0.53	GO:0006351	transcription, DNA-templated
0.52	GO:0006355	regulation of transcription, DNA-templated

0.81	GO:0004407	histone deacetylase activity
0.70	GO:0034979	NAD-dependent protein deacetylase activity
0.67	GO:0003714	transcription corepressor activity
0.57	GO:0051059	NF-kappaB binding
0.55	GO:0042826	histone deacetylase binding
0.54	GO:0030332	cyclin binding
0.53	GO:0003682	chromatin binding
0.52	GO:0046872	metal ion binding
0.35	GO:0070491	repressing transcription factor binding
0.34	GO:0051020	GTPase binding

0.56	GO:0005634	nucleus
0.55	GO:0017053	transcriptional repressor complex
0.54	GO:0005876	spindle microtubule
0.49	GO:0005794	Golgi apparatus
0.48	GO:0005829	cytosol
0.47	GO:0070013	intracellular organelle lumen
0.42	GO:0005886	plasma membrane
0.35	GO:1902494	catalytic complex
0.34	GO:0000785	chromatin
0.30	GO:0016021	integral component of membrane

0.81

EC:3.5.1.98

GO:0004407

sp|Q803C7|LMBRL_DANRE
Limb region 1 homolog-like protein
Search

LMBR1L

0.97	Limb development membrane protein 1 like

0.50

GO:0006897

endocytosis

0.47

GO:0004872

receptor activity

0.48

GO:0005887

integral component of plasma membrane

sp|Q803C9|PTSS1_DANRE
Phosphatidylserine synthase 1
Search

PTDSS1

0.91	Phosphatidylserine synthase 1

0.84

GO:0006659

phosphatidylserine biosynthetic process

0.35

GO:0016740

transferase activity

0.47	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0016740

tr|Q803D1|Q803D1_DANRE
ADP-ribosylation factor 1
Search

ARF1

0.75	ADP-ribosylation factor 1

0.54	GO:1990386	mitotic cleavage furrow ingression
0.49	GO:0098586	cellular response to virus
0.49	GO:0016192	vesicle-mediated transport
0.48	GO:0006878	cellular copper ion homeostasis
0.41	GO:0060292	long term synaptic depression
0.41	GO:0097061	dendritic spine organization
0.40	GO:0002090	regulation of receptor internalization
0.40	GO:1903337	positive regulation of vacuolar transport
0.40	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation
0.40	GO:1902822	regulation of late endosome to lysosome transport

0.66	GO:0005525	GTP binding
0.47	GO:0019904	protein domain specific binding
0.46	GO:0046982	protein heterodimerization activity
0.43	GO:0000287	magnesium ion binding
0.40	GO:1990583	phospholipase D activator activity
0.38	GO:0019003	GDP binding
0.34	GO:0003924	GTPase activity
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0005102	receptor binding
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.51	GO:0005794	Golgi apparatus
0.48	GO:0030017	sarcomere
0.48	GO:0031252	cell leading edge
0.44	GO:0005829	cytosol
0.41	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0043234	protein complex
0.39	GO:0031982	vesicle
0.39	GO:0014069	postsynaptic density
0.38	GO:0043230	extracellular organelle
0.38	GO:0045211	postsynaptic membrane

0.33

GO:0003755

sp|Q803D2|LIS1B_DANRE
Lissencephaly-1 homolog B
Search

PAFAH1B1

0.87	Platelet-activating factor acetylhydrolase IB subunit alpha

0.81	GO:0000132	establishment of mitotic spindle orientation
0.71	GO:0007399	nervous system development
0.68	GO:0030154	cell differentiation
0.66	GO:0051301	cell division
0.57	GO:0008090	retrograde axonal transport
0.55	GO:0090176	microtubule cytoskeleton organization involved in establishment of planar polarity
0.55	GO:0047496	vesicle transport along microtubule
0.54	GO:0051081	nuclear envelope disassembly
0.54	GO:0051661	maintenance of centrosome location
0.54	GO:0042249	establishment of planar polarity of embryonic epithelium

0.80	GO:0070840	dynein complex binding
0.51	GO:0051219	phosphoprotein binding
0.49	GO:0008017	microtubule binding
0.48	GO:0042803	protein homodimerization activity
0.41	GO:0016787	hydrolase activity
0.38	GO:0045505	dynein intermediate chain binding
0.37	GO:0034452	dynactin binding
0.37	GO:0043274	phospholipase binding
0.36	GO:0008201	heparin binding
0.35	GO:0047179	platelet-activating factor acetyltransferase activity

0.73	GO:0005874	microtubule
0.72	GO:0005875	microtubule associated complex
0.72	GO:0005815	microtubule organizing center
0.57	GO:0005819	spindle
0.57	GO:0031965	nuclear membrane
0.55	GO:1904115	axon cytoplasm
0.52	GO:0000776	kinetochore
0.52	GO:0032420	stereocilium
0.51	GO:0005938	cell cortex
0.50	GO:0031252	cell leading edge

0.41

GO:0016787

sp|Q803E0|PALD_DANRE
Paladin
Search

PALD1

0.96	Phosphatase domain containing, paladin 1

0.60	GO:0016311	dephosphorylation
0.50	GO:0006464	cellular protein modification process
0.41	GO:0001525	angiogenesis
0.36	GO:0007050	cell cycle arrest
0.35	GO:0006508	proteolysis
0.35	GO:1903047	mitotic cell cycle process
0.35	GO:0044843	cell cycle G1/S phase transition
0.34	GO:0051255	spindle midzone assembly
0.34	GO:0051231	spindle elongation
0.33	GO:0007096	regulation of exit from mitosis

0.61	GO:0016791	phosphatase activity
0.49	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0005515	protein binding

0.60	GO:0005829	cytosol
0.50	GO:0005634	nucleus
0.33	GO:0072686	mitotic spindle
0.33	GO:0000922	spindle pole
0.33	GO:0005813	centrosome
0.30	GO:0016020	membrane

0.61

EC:3.1.3 EC:3.1.3.41

GO:0016791

sp|Q803E1|NCBP3_DANRE
Nuclear cap-binding protein subunit 3
Search

NCBP3

0.92	Nuclear cap-binding protein subunit 3

0.55	GO:0051607	defense response to virus
0.46	GO:0051028	mRNA transport
0.46	GO:0006370	7-methylguanosine mRNA capping

0.85	GO:0000340	RNA 7-methylguanosine cap binding
0.76	GO:0003729	mRNA binding
0.34	GO:0005515	protein binding

0.57	GO:0016607	nuclear speck
0.42	GO:0005737	cytoplasm
0.37	GO:0034518	RNA cap binding complex

tr|Q803E5|Q803E5_DANRE
Eukaryotic translation termination factor 1
Search

ETF1

0.79	eukaryotic peptide chain release factor subunit 1

0.74	GO:0006415	translational termination
0.46	GO:0008213	protein alkylation
0.44	GO:0043414	macromolecule methylation
0.42	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.42	GO:0007420	brain development
0.34	GO:0006449	regulation of translational termination
0.33	GO:0016032	viral process

0.75	GO:0008079	translation termination factor activity
0.53	GO:1990825	sequence-specific mRNA binding
0.34	GO:0043022	ribosome binding
0.33	GO:0005515	protein binding

0.49	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|Q803F0|Q803F0_DANRE
TGFB-induced factor
Search

TGIF1

0.96	TGFB-induced factor homeobox 1

0.59	GO:0000122	negative regulation of transcription by RNA polymerase II
0.55	GO:0021797	forebrain anterior/posterior pattern specification
0.55	GO:0070654	sensory epithelium regeneration
0.55	GO:0048385	regulation of retinoic acid receptor signaling pathway
0.53	GO:0048854	brain morphogenesis
0.52	GO:0072091	regulation of stem cell proliferation
0.52	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
0.38	GO:0038092	nodal signaling pathway
0.38	GO:0048146	positive regulation of fibroblast proliferation
0.38	GO:0010470	regulation of gastrulation

0.63	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.60	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.38	GO:0070410	co-SMAD binding
0.36	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.52	GO:0031974	membrane-enclosed lumen
0.47	GO:0044446	intracellular organelle part

tr|Q803F2|Q803F2_DANRE
Ras homolog family member Gb
Search

RHOG

0.94	Ras homolog gene family, member Gb

0.77	GO:0007264	small GTPase mediated signal transduction
0.66	GO:1903078	positive regulation of protein localization to plasma membrane
0.65	GO:1900027	regulation of ruffle assembly
0.65	GO:0090630	activation of GTPase activity
0.63	GO:0060326	cell chemotaxis
0.58	GO:0030036	actin cytoskeleton organization
0.57	GO:0045893	positive regulation of transcription, DNA-templated
0.49	GO:0009617	response to bacterium

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005622	intracellular
0.41	GO:0005925	focal adhesion
0.41	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|Q803F5|APMAP_DANRE
Adipocyte plasma membrane-associated protein
Search

APMAP

0.93	adipocyte plasma membrane-associated protein isoform X1

0.48	GO:0009058	biosynthetic process
0.32	GO:0006259	DNA metabolic process

0.81	GO:0016844	strictosidine synthase activity
0.56	GO:0004064	arylesterase activity

0.51	GO:0009986	cell surface
0.42	GO:0005783	endoplasmic reticulum
0.36	GO:0070062	extracellular exosome
0.33	GO:0000811	GINS complex
0.30	GO:0031224	intrinsic component of membrane

0.81	EC:4.3.3.2	GO:0016844
0.81	KEGG:R03738	GO:0016844

sp|Q803F6|RSSA_DANRE
40S ribosomal protein SA
Search

RPSA

0.73	Ribosomal protein SA

0.77	GO:0000028	ribosomal small subunit assembly
0.66	GO:0007155	cell adhesion
0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.48	GO:0006407	rRNA export from nucleus
0.42	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.42	GO:0016072	rRNA metabolic process
0.37	GO:0030855	epithelial cell differentiation

0.85	GO:0005055	laminin receptor activity
0.80	GO:0043236	laminin binding
0.63	GO:0003735	structural constituent of ribosome
0.38	GO:0001618	virus receptor activity
0.36	GO:0043022	ribosome binding
0.33	GO:0003723	RNA binding

0.74	GO:0022627	cytosolic small ribosomal subunit
0.58	GO:0005634	nucleus
0.53	GO:0005886	plasma membrane
0.46	GO:0030686	90S preribosome
0.37	GO:0005604	basement membrane
0.37	GO:0043025	neuronal cell body
0.36	GO:0070062	extracellular exosome
0.35	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.33	GO:0043233	organelle lumen

tr|Q803G3|Q803G3_DANRE
Serine/threonine-protein phosphatase
Search

0.47	Serine/threonine-protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.52	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.52	GO:0008637	apoptotic mitochondrial changes
0.51	GO:0042542	response to hydrogen peroxide
0.50	GO:0007498	mesoderm development
0.49	GO:0034976	response to endoplasmic reticulum stress
0.48	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.48	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.47	GO:0046677	response to antibiotic
0.42	GO:1904528	positive regulation of microtubule binding

0.72	GO:0004721	phosphoprotein phosphatase activity
0.52	GO:0050811	GABA receptor binding
0.51	GO:0008022	protein C-terminus binding
0.48	GO:0046982	protein heterodimerization activity
0.37	GO:0046872	metal ion binding
0.35	GO:1990405	protein antigen binding
0.35	GO:0031698	beta-2 adrenergic receptor binding
0.35	GO:0048156	tau protein binding
0.35	GO:0043422	protein kinase B binding
0.35	GO:0051721	protein phosphatase 2A binding

0.58	GO:0000159	protein phosphatase type 2A complex
0.50	GO:0000775	chromosome, centromeric region
0.45	GO:0005829	cytosol
0.43	GO:0000922	spindle pole
0.40	GO:0005886	plasma membrane
0.39	GO:0005634	nucleus
0.38	GO:0070062	extracellular exosome
0.35	GO:0043195	terminal bouton
0.34	GO:0014069	postsynaptic density
0.33	GO:0005739	mitochondrion

0.72

GO:0004721

sp|Q803G5|SAM5A_DANRE
Sorting and assembly machinery component 50 homolog A
Search

SAMM50

0.96	Sorting and assembly machinery component 50

0.53	GO:0042407	cristae formation
0.51	GO:0045040	protein import into mitochondrial outer membrane
0.50	GO:0033108	mitochondrial respiratory chain complex assembly
0.35	GO:0001889	liver development
0.32	GO:0006629	lipid metabolic process

0.34	GO:0005515	protein binding
0.34	GO:0005509	calcium ion binding

0.66	GO:0019867	outer membrane
0.48	GO:0098805	whole membrane
0.47	GO:0098588	bounding membrane of organelle
0.47	GO:0098798	mitochondrial protein complex
0.47	GO:0044455	mitochondrial membrane part
0.42	GO:0098796	membrane protein complex
0.42	GO:0019866	organelle inner membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q803H0|CG025_DANRE
UPF0415 protein C7orf25 homolog
Search

0.28	Proteasome endopeptidase complex

0.58	GO:0051603	proteolysis involved in cellular protein catabolic process
0.47	GO:0043632	modification-dependent macromolecule catabolic process
0.36	GO:0051304	chromosome separation
0.34	GO:0051301	cell division

0.62	GO:0070003	threonine-type peptidase activity
0.54	GO:0004175	endopeptidase activity
0.43	GO:0005515	protein binding

0.61	GO:0005839	proteasome core complex
0.42	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm

tr|Q803H1|Q803H1_DANRE
RNA binding motif protein 39a
Search

RBM39

0.83	RNA binding motif protein 39

0.69	GO:0006397	mRNA processing
0.37	GO:0008380	RNA splicing
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:2001141	regulation of RNA biosynthetic process
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression

0.58	GO:0003723	RNA binding
0.35	GO:0003713	transcription coactivator activity
0.35	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.52	GO:0005815	microtubule organizing center
0.48	GO:0031974	membrane-enclosed lumen
0.44	GO:0043234	protein complex

tr|Q803H2|Q803H2_DANRE
Cytochrome c heme lyase
Search

HCCS

0.65	Cytochrome c-type heme lyase

0.49	GO:0018063	cytochrome c-heme linkage
0.34	GO:0009887	animal organ morphogenesis
0.32	GO:0055114	oxidation-reduction process

0.85	GO:0004408	holocytochrome-c synthase activity
0.54	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane

0.85

EC:4.4.1.17

GO:0004408

sp|Q803H4|CENPA_DANRE
Histone H3-like centromeric protein A
Search

CENPA

0.73	Centromeric protein A

0.49	GO:0061641	CENP-A containing chromatin organization
0.43	GO:0006334	nucleosome assembly
0.41	GO:0051382	kinetochore assembly
0.40	GO:0000070	mitotic sister chromatid segregation
0.33	GO:0006468	protein phosphorylation

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.45	GO:0031491	nucleosome binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003723	RNA binding
0.32	GO:0030554	adenyl nucleotide binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.49	GO:0061638	CENP-A containing chromatin
0.48	GO:0000779	condensed chromosome, centromeric region
0.42	GO:0031974	membrane-enclosed lumen
0.42	GO:0000776	kinetochore

tr|Q803H5|Q803H5_DANRE
Gnb1l protein
Search

GNB1

0.91	Guanine nucleotide-binding protein beta subunit

0.61	GO:0007165	signal transduction
0.52	GO:0060041	retina development in camera-type eye
0.51	GO:0050909	sensory perception of taste
0.50	GO:0008283	cell proliferation
0.41	GO:0010659	cardiac muscle cell apoptotic process
0.40	GO:0070208	protein heterotrimerization
0.40	GO:0048920	posterior lateral line neuromast primordium migration
0.39	GO:0071456	cellular response to hypoxia
0.39	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.37	GO:0071380	cellular response to prostaglandin E stimulus

0.50	GO:0032403	protein complex binding
0.48	GO:0051020	GTPase binding
0.46	GO:0003924	GTPase activity
0.41	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity
0.41	GO:0031702	type 1 angiotensin receptor binding
0.40	GO:0030507	spectrin binding
0.38	GO:0004871	signal transducer activity

0.53	GO:0043209	myelin sheath
0.52	GO:0001750	photoreceptor outer segment
0.52	GO:1905360	GTPase complex
0.51	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.45	GO:0098797	plasma membrane protein complex
0.41	GO:0060170	ciliary membrane
0.40	GO:0001917	photoreceptor inner segment
0.39	GO:0030425	dendrite
0.39	GO:0044297	cell body
0.37	GO:0005765	lysosomal membrane

0.41

EC:3.1.4.39

GO:0047391

tr|Q803H7|Q803H7_DANRE
Integral membrane protein 2Ba
Search

ITM2B

0.96	Integral membrane protein 2Ba

0.60	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process
0.44	GO:0007399	nervous system development
0.39	GO:0006915	apoptotic process
0.38	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.38	GO:0008285	negative regulation of cell proliferation
0.36	GO:0045892	negative regulation of transcription, DNA-templated
0.36	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0038034	signal transduction in absence of ligand
0.36	GO:0002317	plasma cell differentiation
0.35	GO:0002377	immunoglobulin production

0.57	GO:0001540	amyloid-beta binding
0.41	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0008134	transcription factor binding

0.51	GO:0030660	Golgi-associated vesicle membrane
0.51	GO:0005615	extracellular space
0.50	GO:0031301	integral component of organelle membrane
0.50	GO:0005794	Golgi apparatus
0.46	GO:1903561	extracellular vesicle
0.42	GO:0005886	plasma membrane
0.41	GO:0010008	endosome membrane
0.39	GO:0035189	Rb-E2F complex
0.39	GO:0031984	organelle subcompartment

sp|Q803I2|ERGI3_DANRE
Endoplasmic reticulum-Golgi intermediate compartment protein 3
Search

ERGIC3

0.93	ERGIC and golgi 3

0.30

GO:0044425

membrane part

sp|Q803I4|RING2_DANRE
E3 ubiquitin-protein ligase RING2
Search

RNF2

0.94	Ring finger protein 2

0.86	GO:0036353	histone H2A-K119 monoubiquitination
0.84	GO:0001702	gastrulation with mouth forming second
0.82	GO:0009948	anterior/posterior axis specification
0.81	GO:0043433	negative regulation of DNA binding transcription factor activity
0.77	GO:0007281	germ cell development
0.76	GO:0000122	negative regulation of transcription by RNA polymerase II
0.73	GO:0000278	mitotic cell cycle

0.87	GO:0071535	RING-like zinc finger domain binding
0.75	GO:0003682	chromatin binding
0.74	GO:0061630	ubiquitin protein ligase activity
0.61	GO:0008270	zinc ion binding

0.86	GO:0001739	sex chromatin
0.85	GO:0035102	PRC1 complex
0.82	GO:0000791	euchromatin
0.80	GO:0071339	MLL1 complex
0.76	GO:0016604	nuclear body

tr|Q803I7|Q803I7_DANRE
Phosphoserine aminotransferase
Search

PSAT1

0.51	Phosphoserine aminotransferase

0.76	GO:0006564	L-serine biosynthetic process
0.34	GO:0008615	pyridoxine biosynthetic process
0.33	GO:1902600	hydrogen ion transmembrane transport
0.32	GO:0022900	electron transport chain

0.79	GO:0004648	O-phospho-L-serine:2-oxoglutarate aminotransferase activity
0.33	GO:0015002	heme-copper terminal oxidase activity
0.33	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.33	GO:0015078	hydrogen ion transmembrane transporter activity
0.32	GO:0009055	electron transfer activity

0.47	GO:0005829	cytosol
0.40	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.79

EC:2.6.1.52

GO:0004648

sp|Q803I8|SYVN1_DANRE
E3 ubiquitin-protein ligase synoviolin
Search

SYVN1

0.90	Synovial apoptosis inhibitor 1, synoviolin

0.80	GO:0030433	ubiquitin-dependent ERAD pathway
0.71	GO:0016567	protein ubiquitination
0.59	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.58	GO:0018279	protein N-linked glycosylation via asparagine
0.58	GO:1903513	endoplasmic reticulum to cytosol transport
0.57	GO:0032527	protein exit from endoplasmic reticulum
0.54	GO:0050821	protein stabilization
0.49	GO:0030968	endoplasmic reticulum unfolded protein response
0.37	GO:0001701	in utero embryonic development
0.36	GO:1904380	endoplasmic reticulum mannose trimming

0.74	GO:0061630	ubiquitin protein ligase activity
0.61	GO:1990381	ubiquitin-specific protease binding
0.57	GO:0051117	ATPase binding
0.53	GO:0051087	chaperone binding
0.51	GO:0051082	unfolded protein binding
0.49	GO:0016874	ligase activity
0.36	GO:0046872	metal ion binding

0.83	GO:0000836	Hrd1p ubiquitin ligase complex
0.60	GO:0036513	Derlin-1 retrotranslocation complex
0.58	GO:0005790	smooth endoplasmic reticulum
0.51	GO:0044322	endoplasmic reticulum quality control compartment
0.49	GO:0005654	nucleoplasm
0.35	GO:0030176	integral component of endoplasmic reticulum membrane

0.49

GO:0016874

tr|Q803J2|Q803J2_DANRE
Ube2n protein
Search

UBE2N

0.61	Ubiquitin-conjugating enzyme

0.53	GO:0000209	protein polyubiquitination
0.50	GO:0006301	postreplication repair
0.46	GO:0042769	DNA damage response, detection of DNA damage
0.45	GO:0033182	regulation of histone ubiquitination
0.44	GO:0000729	DNA double-strand break processing
0.44	GO:0045739	positive regulation of DNA repair
0.44	GO:0031058	positive regulation of histone modification
0.44	GO:0050852	T cell receptor signaling pathway
0.44	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.44	GO:0016574	histone ubiquitination

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0004842	ubiquitin-protein transferase activity
0.47	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0061659	ubiquitin-like protein ligase activity
0.45	GO:0061650	ubiquitin-like protein conjugating enzyme activity
0.43	GO:0043130	ubiquitin binding
0.34	GO:0016874	ligase activity
0.33	GO:0003723	RNA binding

0.46	GO:0031372	UBC13-MMS2 complex
0.46	GO:0035370	UBC13-UEV1A complex
0.44	GO:0005634	nucleus
0.42	GO:0000151	ubiquitin ligase complex
0.40	GO:0043233	organelle lumen
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0005737	cytoplasm
0.37	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome

0.34	EC:6	GO:0016874
0.49	KEGG:R03876	GO:0004842

tr|Q803J3|Q803J3_DANRE
RAB2A, member RAS oncogene family
Search

RAB2A

0.93	RAS oncogene family member RAB2

0.62

GO:0007030

Golgi organization

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.58

GO:0005794

Golgi apparatus

tr|Q803J4|Q803J4_DANRE
Heterogeneous nuclear ribonucleoprotein C
Search

0.95	Heterogeneous nuclear ribonucleoprotein C

0.40	GO:0070935	3'-UTR-mediated mRNA stabilization
0.40	GO:0032211	negative regulation of telomere maintenance via telomerase
0.38	GO:0000398	mRNA splicing, via spliceosome
0.36	GO:0001649	osteoblast differentiation
0.35	GO:0043044	ATP-dependent chromatin remodeling
0.35	GO:0090367	negative regulation of mRNA modification
0.35	GO:0051492	regulation of stress fiber assembly
0.33	GO:0043086	negative regulation of catalytic activity

0.59	GO:0003723	RNA binding
0.38	GO:0042802	identical protein binding
0.36	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.36	GO:0031492	nucleosomal DNA binding
0.35	GO:1990827	deaminase binding
0.35	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0019904	protein domain specific binding
0.33	GO:0004857	enzyme inhibitor activity
0.33	GO:0043021	ribonucleoprotein complex binding

0.58	GO:0019013	viral nucleocapsid
0.51	GO:0030529	intracellular ribonucleoprotein complex
0.44	GO:0045120	pronucleus
0.39	GO:0005654	nucleoplasm
0.38	GO:0015629	actin cytoskeleton
0.37	GO:0005829	cytosol
0.36	GO:0005576	extracellular region
0.36	GO:1902494	catalytic complex
0.35	GO:0043234	protein complex
0.35	GO:0000790	nuclear chromatin

tr|Q803J6|Q803J6_DANRE
Sdcbp protein
Search

SDCBP

0.91	Putative pdz domain containing protein found in a variety of eumetazoan signaling molecules

0.77	GO:0007268	chemical synaptic transmission
0.73	GO:0030036	actin cytoskeleton organization
0.62	GO:0035556	intracellular signal transduction
0.50	GO:0030307	positive regulation of cell growth
0.49	GO:0030335	positive regulation of cell migration
0.48	GO:0008284	positive regulation of cell proliferation
0.46	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.45	GO:0042246	tissue regeneration
0.45	GO:0007416	synapse assembly
0.44	GO:0001666	response to hypoxia

0.54	GO:0005137	interleukin-5 receptor binding
0.50	GO:0045545	syndecan binding
0.46	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.38	GO:0050839	cell adhesion molecule binding
0.37	GO:0005109	frizzled binding
0.37	GO:0042043	neurexin family protein binding
0.37	GO:0046875	ephrin receptor binding
0.37	GO:0047485	protein N-terminus binding
0.37	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.37	GO:0008022	protein C-terminus binding

0.55	GO:0005895	interleukin-5 receptor complex
0.50	GO:0031965	nuclear membrane
0.46	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome
0.37	GO:0042470	melanosome
0.37	GO:0005925	focal adhesion
0.37	GO:0098857	membrane microdomain
0.36	GO:0072562	blood microparticle
0.36	GO:0005789	endoplasmic reticulum membrane

sp|Q803J8|ZC3HF_DANRE
Zinc finger CCCH domain-containing protein 15
Search

ZC3H15

0.92	Zinc finger CCCH domain-containing protein 15

0.49	GO:0019221	cytokine-mediated signaling pathway
0.33	GO:0015991	ATP hydrolysis coupled proton transport
0.33	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.33	GO:0006754	ATP biosynthetic process
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.54	GO:0046872	metal ion binding
0.51	GO:0045296	cadherin binding
0.34	GO:0072544	L-DOPA binding
0.34	GO:0072545	tyrosine binding
0.34	GO:0035240	dopamine binding
0.34	GO:0003723	RNA binding
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.47	GO:0005730	nucleolus
0.46	GO:0005829	cytosol
0.33	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.30	GO:0016021	integral component of membrane

sp|Q803K4|SETD6_DANRE
N-lysine methyltransferase setd6
Search

SETD6

0.93	N-lysine methyltransferase setd6

0.75	GO:0018026	peptidyl-lysine monomethylation
0.52	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.50	GO:0050727	regulation of inflammatory response
0.44	GO:0019827	stem cell population maintenance
0.44	GO:0048863	stem cell differentiation
0.43	GO:0034968	histone lysine methylation

0.69	GO:0016279	protein-lysine N-methyltransferase activity
0.51	GO:0051059	NF-kappaB binding

0.43	GO:0005634	nucleus
0.41	GO:0005829	cytosol
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

0.69

GO:0016279

sp|Q803L0|LN28A_DANRE
Protein lin-28 homolog A
Search

LIN28A

0.38	RNA-binding protein LIN-28

0.59	GO:0010587	miRNA catabolic process
0.57	GO:0031054	pre-miRNA processing
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:2000767	positive regulation of cytoplasmic translation
0.51	GO:0031123	RNA 3'-end processing
0.51	GO:1901724	positive regulation of cell proliferation involved in kidney development
0.50	GO:0019827	stem cell population maintenance
0.50	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA
0.49	GO:0045686	negative regulation of glial cell differentiation
0.49	GO:0071333	cellular response to glucose stimulus

0.63	GO:0008270	zinc ion binding
0.55	GO:0003677	DNA binding
0.55	GO:1905538	polysome binding
0.50	GO:1990825	sequence-specific mRNA binding
0.49	GO:0035198	miRNA binding
0.49	GO:0002151	G-quadruplex RNA binding
0.47	GO:0031369	translation initiation factor binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.50	GO:0005844	polysome
0.50	GO:0000932	P-body
0.49	GO:0005730	nucleolus
0.49	GO:0010494	cytoplasmic stress granule
0.49	GO:0005791	rough endoplasmic reticulum
0.41	GO:0005829	cytosol

tr|Q803L5|Q803L5_DANRE
Serine/threonine kinase 38a
Search

STK38

0.93	Serine/threonine-protein kinase 38

0.62	GO:0006468	protein phosphorylation
0.56	GO:0043407	negative regulation of MAP kinase activity
0.50	GO:0035556	intracellular signal transduction
0.49	GO:0018209	peptidyl-serine modification
0.41	GO:0051128	regulation of cellular component organization

0.68	GO:0004674	protein serine/threonine kinase activity
0.59	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.54	GO:0045296	cadherin binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0000287	magnesium ion binding
0.34	GO:0003779	actin binding

0.53	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.44	GO:0015629	actin cytoskeleton
0.30	GO:0016020	membrane

0.68

GO:0004674

tr|Q803L7|Q803L7_DANRE
Ras homolog gene family, member Gc
Search

0.90	Ras homolog gene family, member Gc

0.77	GO:0007264	small GTPase mediated signal transduction
0.65	GO:1903078	positive regulation of protein localization to plasma membrane
0.65	GO:1900027	regulation of ruffle assembly
0.64	GO:0090630	activation of GTPase activity
0.62	GO:0060326	cell chemotaxis
0.57	GO:0030036	actin cytoskeleton organization
0.57	GO:0045893	positive regulation of transcription, DNA-templated
0.46	GO:0009617	response to bacterium
0.35	GO:0016192	vesicle-mediated transport

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005622	intracellular
0.41	GO:0005925	focal adhesion
0.41	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|Q803M0|PPR3B_DANRE
Protein phosphatase 1 regulatory subunit 3B
Search

PPP1R3B

0.88	Protein phosphatase 1 regulatory subunit

0.85	GO:0005981	regulation of glycogen catabolic process
0.76	GO:0043666	regulation of phosphoprotein phosphatase activity
0.70	GO:0005977	glycogen metabolic process
0.38	GO:0005979	regulation of glycogen biosynthetic process
0.36	GO:0006470	protein dephosphorylation
0.33	GO:0009250	glucan biosynthetic process

0.77	GO:0019888	protein phosphatase regulator activity
0.37	GO:0019899	enzyme binding
0.36	GO:0004721	phosphoprotein phosphatase activity

0.80	GO:0000164	protein phosphatase type 1 complex
0.39	GO:0042587	glycogen granule
0.34	GO:0043231	intracellular membrane-bounded organelle

0.36

GO:0004721

sp|Q803M3|TEX10_DANRE
Testis-expressed protein 10 homolog
Search

TEX10

0.97	Testis-expressed protein 10

0.38	GO:0006364	rRNA processing
0.33	GO:1902299	pre-replicative complex assembly involved in cell cycle DNA replication
0.33	GO:0033260	nuclear DNA replication
0.33	GO:0030174	regulation of DNA-dependent DNA replication initiation
0.32	GO:0000027	ribosomal large subunit assembly

0.36	GO:0005515	protein binding
0.32	GO:0003682	chromatin binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0004386	helicase activity
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.81	GO:0071339	MLL1 complex
0.71	GO:0097344	Rix1 complex
0.48	GO:0005730	nucleolus
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q803M4|Q803M4_DANRE
Ubiquitin-conjugating enzyme E2 A,-like
Search

UBE2A

0.61	Ubiquitin-conjugating enzyme

0.55	GO:0070979	protein K11-linked ubiquitination
0.55	GO:0033522	histone H2A ubiquitination
0.55	GO:0070936	protein K48-linked ubiquitination
0.54	GO:0051865	protein autoubiquitination
0.52	GO:0009411	response to UV
0.49	GO:0001701	in utero embryonic development
0.49	GO:0060135	maternal process involved in female pregnancy
0.48	GO:0008284	positive regulation of cell proliferation
0.47	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.46	GO:0006281	DNA repair

0.55	GO:0061631	ubiquitin conjugating enzyme activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0043130	ubiquitin binding

0.57	GO:0033503	HULC complex
0.54	GO:0001741	XY body
0.50	GO:0000790	nuclear chromatin
0.40	GO:0005657	replication fork
0.37	GO:0005737	cytoplasm
0.34	GO:0005654	nucleoplasm
0.33	GO:0005886	plasma membrane

sp|Q803M5|SAAL1_DANRE
Protein saal1
Search

SAAL1

0.97	Synoviocyte proliferation-associated in collagen-induced arthritis 1

0.41	GO:0009072	aromatic amino acid family metabolic process
0.38	GO:0042427	serotonin biosynthetic process
0.37	GO:0036065	fucosylation
0.37	GO:0055114	oxidation-reduction process
0.36	GO:0043413	macromolecule glycosylation
0.36	GO:0009101	glycoprotein biosynthetic process
0.35	GO:0006953	acute-phase response
0.34	GO:0036211	protein modification process
0.34	GO:0044267	cellular protein metabolic process

0.45	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
0.39	GO:0005506	iron ion binding
0.37	GO:0008417	fucosyltransferase activity

0.67	GO:0005615	extracellular space
0.46	GO:0005634	nucleus
0.44	GO:0005581	collagen trimer
0.37	GO:0032580	Golgi cisterna membrane
0.35	GO:1990777	lipoprotein particle
0.30	GO:0016021	integral component of membrane

0.45

EC:1.14.16

GO:0016714

tr|Q803M8|Q803M8_DANRE
Tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
Search

YWHAZ

0.83	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

0.51	GO:0090168	Golgi reassembly
0.50	GO:0051683	establishment of Golgi localization
0.45	GO:0010941	regulation of cell death
0.44	GO:0006605	protein targeting
0.38	GO:0055114	oxidation-reduction process
0.36	GO:0030590	first cell cycle pseudocleavage
0.36	GO:0010070	zygote asymmetric cell division
0.36	GO:0035046	pronuclear migration
0.36	GO:0009949	polarity specification of anterior/posterior axis
0.36	GO:0045167	asymmetric protein localization involved in cell fate determination

0.77	GO:0019904	protein domain specific binding
0.48	GO:0044325	ion channel binding
0.47	GO:0045296	cadherin binding
0.46	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0019901	protein kinase binding
0.44	GO:0042802	identical protein binding
0.44	GO:0008134	transcription factor binding
0.43	GO:0004497	monooxygenase activity
0.34	GO:0003723	RNA binding
0.34	GO:0032403	protein complex binding

0.41	GO:0005634	nucleus
0.41	GO:0005739	mitochondrion
0.40	GO:0042470	melanosome
0.36	GO:0072562	blood microparticle
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0030659	cytoplasmic vesicle membrane
0.35	GO:0042629	mast cell granule
0.35	GO:0005938	cell cortex
0.34	GO:0005829	cytosol

tr|Q803N1|Q803N1_DANRE
Tfdp1l protein
Search

TFDP1

0.93	Transcription factor Dp-1

0.66	GO:0007049	cell cycle
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0070345	negative regulation of fat cell proliferation
0.52	GO:0043276	anoikis
0.49	GO:1902680	positive regulation of RNA biosynthetic process
0.48	GO:0008544	epidermis development
0.46	GO:0051052	regulation of DNA metabolic process

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.46	GO:0008134	transcription factor binding
0.45	GO:0019904	protein domain specific binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.43	GO:0003712	transcription cofactor activity
0.37	GO:0015299	solute:proton antiporter activity

0.74	GO:0005667	transcription factor complex
0.60	GO:0005634	nucleus
0.40	GO:0031974	membrane-enclosed lumen
0.40	GO:0005829	cytosol
0.39	GO:0044446	intracellular organelle part
0.34	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

tr|Q803N7|Q803N7_DANRE
Casein kinase 2 alpha 1
Search

CSNK2A1

0.77	Casein kinase II subunit alpha

0.63	GO:0006468	protein phosphorylation
0.43	GO:0030307	positive regulation of cell growth
0.42	GO:0045732	positive regulation of protein catabolic process
0.42	GO:0008284	positive regulation of cell proliferation
0.42	GO:0051336	regulation of hydrolase activity
0.41	GO:0030177	positive regulation of Wnt signaling pathway
0.41	GO:0032268	regulation of cellular protein metabolic process
0.41	GO:0035303	regulation of dephosphorylation
0.41	GO:1905818	regulation of chromosome separation
0.40	GO:0043066	negative regulation of apoptotic process

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0008013	beta-catenin binding
0.41	GO:0019888	protein phosphatase regulator activity
0.41	GO:0047485	protein N-terminus binding
0.38	GO:0042802	identical protein binding
0.36	GO:0043021	ribonucleoprotein complex binding

0.42	GO:0031519	PcG protein complex
0.40	GO:0016580	Sin3 complex
0.40	GO:0016581	NuRD complex
0.40	GO:0005956	protein kinase CK2 complex
0.34	GO:0005886	plasma membrane
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0004674

sp|Q803N9|BZW1B_DANRE
Basic leucine zipper and W2 domain-containing protein 1-B
Search

BZW1

0.91	Basic leucine zipper and W2 domain-containing protein 1-B

0.44	GO:0006351	transcription, DNA-templated
0.44	GO:2001141	regulation of RNA biosynthetic process
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.37	GO:0007399	nervous system development
0.37	GO:0022900	electron transport chain
0.37	GO:0030154	cell differentiation

0.75	GO:0045296	cadherin binding
0.39	GO:0051537	2 iron, 2 sulfur cluster binding
0.38	GO:0050660	flavin adenine dinucleotide binding
0.38	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.37	GO:0009055	electron transfer activity
0.37	GO:0003723	RNA binding
0.36	GO:0046872	metal ion binding

0.46	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.38

EC:1.1

GO:0016614

sp|Q803P1|EI3JB_DANRE
Eukaryotic translation initiation factor 3 subunit J-B
Search

EIF3J

0.73	Eukaryotic translation initiation factor 3 subunit J-B

0.71	GO:0006413	translational initiation
0.67	GO:0002181	cytoplasmic translation
0.67	GO:0006446	regulation of translational initiation
0.64	GO:0022618	ribonucleoprotein complex assembly
0.34	GO:0016311	dephosphorylation
0.33	GO:1903507	negative regulation of nucleic acid-templated transcription

0.72	GO:0003743	translation initiation factor activity
0.34	GO:0016791	phosphatase activity
0.34	GO:0003714	transcription corepressor activity
0.33	GO:0005515	protein binding

0.77	GO:0005852	eukaryotic translation initiation factor 3 complex
0.68	GO:0016282	eukaryotic 43S preinitiation complex
0.68	GO:0033290	eukaryotic 48S preinitiation complex
0.45	GO:0005829	cytosol

0.34

EC:3.1.3 EC:3.1.3.41

GO:0016791

tr|Q803P2|Q803P2_DANRE
T-complex 1
Search

TCP1

0.76	T-complex protein 1 subunit alpha

0.66	GO:0006457	protein folding
0.60	GO:0044053	translocation of peptides or proteins into host cell cytoplasm
0.59	GO:0090670	RNA localization to Cajal body
0.59	GO:2000109	regulation of macrophage apoptotic process
0.58	GO:1904869	regulation of protein localization to Cajal body
0.58	GO:1904851	positive regulation of establishment of protein localization to telomere
0.57	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.57	GO:0051973	positive regulation of telomerase activity
0.56	GO:0007339	binding of sperm to zona pellucida
0.56	GO:0032212	positive regulation of telomere maintenance via telomerase

0.68	GO:0051082	unfolded protein binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0044183	protein binding involved in protein folding
0.34	GO:0003723	RNA binding
0.33	GO:0005216	ion channel activity

0.58	GO:0002199	zona pellucida receptor complex
0.58	GO:0005832	chaperonin-containing T-complex
0.57	GO:0000242	pericentriolar material
0.55	GO:0001669	acrosomal vesicle
0.55	GO:0005720	nuclear heterochromatin
0.54	GO:0043209	myelin sheath
0.53	GO:0044297	cell body
0.50	GO:0005874	microtubule
0.49	GO:0005794	Golgi apparatus
0.37	GO:0070062	extracellular exosome

tr|Q803P4|Q803P4_DANRE
Fatty acid hydroxylase domain-containing 2
Search

FAXDC2

0.96	fatty acid hydroxylase domain-containing protein 2

0.65	GO:0008610	lipid biosynthetic process
0.53	GO:0055114	oxidation-reduction process

0.63	GO:0005506	iron ion binding
0.54	GO:0016491	oxidoreductase activity

0.43	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.54

GO:0016491

sp|Q803Q2|NDL1B_DANRE
Nuclear distribution protein nudE-like 1-B
Search

NDEL1

0.93	NudE neurodevelopment protein 1 like 1

0.86	GO:0060052	neurofilament cytoskeleton organization
0.86	GO:0007100	mitotic centrosome separation
0.85	GO:2000574	regulation of microtubule motor activity
0.74	GO:0007399	nervous system development
0.55	GO:1900029	positive regulation of ruffle assembly
0.55	GO:0051642	centrosome localization
0.54	GO:0047496	vesicle transport along microtubule
0.53	GO:0032418	lysosome localization
0.52	GO:0008090	retrograde axonal transport
0.51	GO:0001833	inner cell mass cell proliferation

0.51	GO:0043014	alpha-tubulin binding
0.50	GO:0048487	beta-tubulin binding
0.49	GO:0008017	microtubule binding
0.47	GO:0042802	identical protein binding
0.39	GO:0070012	oligopeptidase activity
0.36	GO:0032403	protein complex binding
0.34	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0060053	neurofilament cytoskeleton
0.53	GO:0043203	axon hillock
0.52	GO:0000776	kinetochore
0.51	GO:1904115	axon cytoplasm
0.51	GO:0005813	centrosome
0.50	GO:0005875	microtubule associated complex
0.49	GO:0008021	synaptic vesicle
0.49	GO:0031252	cell leading edge
0.42	GO:0005819	spindle
0.41	GO:0005874	microtubule

0.34

EC:2.7.10.1

GO:0004714

sp|Q803Q4|DEP1A_DANRE
DEP domain-containing protein 1A
Search

DEPDC1

0.95	DEP domain-containing protein 7

0.61	GO:0035556	intracellular signal transduction
0.51	GO:0045892	negative regulation of transcription, DNA-templated
0.41	GO:0043547	positive regulation of GTPase activity
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0030177	positive regulation of Wnt signaling pathway
0.34	GO:0016477	cell migration
0.33	GO:0055114	oxidation-reduction process

0.41	GO:0005096	GTPase activator activity
0.36	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.34	GO:0005515	protein binding

0.58	GO:0017053	transcriptional repressor complex
0.47	GO:0005634	nucleus

0.36

EC:1.13.11

GO:0016702

tr|Q803Q7|Q803Q7_DANRE
Fructose-bisphosphate aldolase
Search

ALDOA

0.54	Fructose-bisphosphate aldolase A

0.70	GO:0006096	glycolytic process
0.50	GO:0030388	fructose 1,6-bisphosphate metabolic process
0.46	GO:0060429	epithelium development
0.45	GO:0046716	muscle cell cellular homeostasis
0.45	GO:0007339	binding of sperm to zona pellucida
0.45	GO:0006941	striated muscle contraction
0.45	GO:0001966	thigmotaxis
0.44	GO:0006000	fructose metabolic process
0.44	GO:0030154	cell differentiation
0.43	GO:0043473	pigmentation

0.78	GO:0004332	fructose-bisphosphate aldolase activity
0.47	GO:0070061	fructose binding
0.45	GO:0008092	cytoskeletal protein binding
0.44	GO:0045296	cadherin binding
0.37	GO:0042802	identical protein binding
0.36	GO:0002020	protease binding
0.35	GO:0061609	fructose-1-phosphate aldolase activity
0.34	GO:0051117	ATPase binding
0.33	GO:0003723	RNA binding

0.46	GO:0061827	sperm head
0.44	GO:0070062	extracellular exosome
0.42	GO:0015629	actin cytoskeleton
0.41	GO:0005829	cytosol
0.40	GO:0031430	M band
0.40	GO:0031674	I band
0.38	GO:0005739	mitochondrion
0.37	GO:0035686	sperm fibrous sheath
0.36	GO:0043209	myelin sheath
0.35	GO:1904724	tertiary granule lumen

0.78

EC:4.1.2.13

GO:0004332

sp|Q803R2|CCZ1_DANRE
Vacuolar fusion protein CCZ1 homolog
Search

CCZ1

0.90	CCZ1 vacuolar protein trafficking and biogenesis associated homolog

0.61	GO:0016192	vesicle-mediated transport
0.51	GO:0065009	regulation of molecular function
0.39	GO:0023052	signaling

0.56	GO:0005085	guanyl-nucleotide exchange factor activity
0.45	GO:0005509	calcium ion binding

0.72	GO:0005765	lysosomal membrane
0.66	GO:0035658	Mon1-Ccz1 complex
0.57	GO:0016235	aggresome
0.48	GO:0005829	cytosol

sp|Q803R5|CMTR1_DANRE
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
Search

CMTR1

0.87	FtsJ methyltransferase domain containing 2

0.80	GO:0080009	mRNA methylation
0.75	GO:0006370	7-methylguanosine mRNA capping
0.38	GO:0033522	histone H2A ubiquitination
0.38	GO:0033523	histone H2B ubiquitination
0.37	GO:0045739	positive regulation of DNA repair
0.37	GO:0010212	response to ionizing radiation
0.37	GO:0006302	double-strand break repair
0.34	GO:0031338	regulation of vesicle fusion
0.34	GO:0090630	activation of GTPase activity
0.34	GO:0051301	cell division

0.82	GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity
0.50	GO:0003676	nucleic acid binding
0.37	GO:0043130	ubiquitin binding
0.37	GO:0042393	histone binding
0.36	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0003682	chromatin binding
0.34	GO:0017137	Rab GTPase binding
0.34	GO:0046872	metal ion binding
0.33	GO:0005096	GTPase activator activity
0.33	GO:0004484	mRNA guanylyltransferase activity

0.47	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.36	GO:0000151	ubiquitin ligase complex
0.35	GO:0030496	midbody
0.35	GO:0000781	chromosome, telomeric region
0.33	GO:0012505	endomembrane system

0.82	EC:2.1.1.57	GO:0004483
0.36	KEGG:R03876	GO:0004842

tr|Q803R8|Q803R8_DANRE
Tmem50a protein
Search

TMEM50A

0.97	Cervical cancer oncogene 9

0.48	GO:0005783	endoplasmic reticulum
0.30	GO:0044425	membrane part

sp|Q803S3|MEMO1_DANRE
Protein MEMO1
Search

MEMO1

0.61	Mediator of cell motility 1

0.79	GO:0032886	regulation of microtubule-based process
0.38	GO:2000145	regulation of cell motility
0.35	GO:0055114	oxidation-reduction process

0.39	GO:0051213	dioxygenase activity
0.39	GO:0042277	peptide binding
0.36	GO:0005515	protein binding

0.51	GO:0005634	nucleus
0.43	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q803T2|STRP1_DANRE
Striatin-interacting protein 1 homolog
Search

STRIP1

0.93	Striatin interacting protein 1

0.76	GO:0030866	cortical actin cytoskeleton organization
0.66	GO:0022604	regulation of cell morphogenesis
0.48	GO:0055117	regulation of cardiac muscle contraction
0.46	GO:0016477	cell migration
0.41	GO:0065008	regulation of biological quality
0.40	GO:0006730	one-carbon metabolic process
0.39	GO:0060047	heart contraction

0.70	GO:0019901	protein kinase binding
0.69	GO:0017048	Rho GTPase binding
0.42	GO:0004013	adenosylhomocysteinase activity

0.64	GO:0005829	cytosol
0.56	GO:0005634	nucleus
0.41	GO:0070062	extracellular exosome

0.42

EC:3.3.1.1

GO:0004013

tr|Q803T5|Q803T5_DANRE
Adenosylhomocysteinase
Search

AHCY

0.56	Adenosylhomocysteinase B

0.78	GO:0019510	S-adenosylhomocysteine catabolic process
0.72	GO:0006730	one-carbon metabolic process
0.49	GO:0033353	S-adenosylmethionine cycle
0.37	GO:0002439	chronic inflammatory response to antigenic stimulus
0.37	GO:0042745	circadian sleep/wake cycle
0.36	GO:0071268	homocysteine biosynthetic process
0.36	GO:0001666	response to hypoxia
0.36	GO:0007584	response to nutrient
0.34	GO:0048033	heme o metabolic process
0.34	GO:0007163	establishment or maintenance of cell polarity

0.80	GO:0004013	adenosylhomocysteinase activity
0.66	GO:0051287	NAD binding
0.38	GO:0043621	protein self-association
0.36	GO:0098604	adenosylselenohomocysteinase activity
0.36	GO:0005507	copper ion binding
0.35	GO:0042802	identical protein binding
0.34	GO:0030552	cAMP binding
0.34	GO:0008495	protoheme IX farnesyltransferase activity

0.47	GO:0005829	cytosol
0.40	GO:0042470	melanosome
0.36	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:0043005	neuron projection
0.35	GO:0031002	actin rod
0.34	GO:0031941	filamentous actin
0.34	GO:0005634	nucleus
0.34	GO:0045335	phagocytic vesicle
0.34	GO:0031252	cell leading edge

0.80

EC:3.3.1.1

GO:0004013

tr|Q803T6|Q803T6_DANRE
SH3-domain GRB2-like 2
Search

SH3GL2

0.90	SH3 domain containing GRB2 like 2, endophilin A1

0.71	GO:0006897	endocytosis
0.55	GO:0072318	clathrin coat disassembly
0.54	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus
0.53	GO:0097484	dendrite extension
0.53	GO:0036465	synaptic vesicle recycling
0.52	GO:0002090	regulation of receptor internalization
0.52	GO:0099003	vesicle-mediated transport in synapse
0.40	GO:0099050	vesicle scission
0.39	GO:0097753	membrane bending
0.39	GO:0097749	membrane tubulation

0.49	GO:0042802	identical protein binding
0.38	GO:0045296	cadherin binding
0.38	GO:0008022	protein C-terminus binding
0.38	GO:0008289	lipid binding
0.37	GO:0019901	protein kinase binding
0.35	GO:0031697	beta-1 adrenergic receptor binding
0.34	GO:0044325	ion channel binding
0.34	GO:0019902	phosphatase binding
0.34	GO:0017124	SH3 domain binding
0.33	GO:0051020	GTPase binding

0.50	GO:0005769	early endosome
0.49	GO:0045202	synapse
0.37	GO:0005829	cytosol
0.36	GO:0002102	podosome
0.36	GO:0070062	extracellular exosome
0.36	GO:0044433	cytoplasmic vesicle part
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0030054	cell junction
0.35	GO:0045334	clathrin-coated endocytic vesicle

tr|Q803U6|Q803U6_DANRE
Aqp3 protein
Search

AQP3

0.55	Aquaporin 3 (Gill blood group)

0.60	GO:0015793	glycerol transport
0.57	GO:0090650	cellular response to oxygen-glucose deprivation
0.56	GO:0015840	urea transport
0.56	GO:0006833	water transport
0.55	GO:0003091	renal water homeostasis
0.55	GO:0055085	transmembrane transport
0.55	GO:0070293	renal absorption
0.53	GO:0032526	response to retinoic acid
0.53	GO:0071456	cellular response to hypoxia
0.52	GO:0042476	odontogenesis

0.69	GO:0022803	passive transmembrane transporter activity
0.60	GO:0015168	glycerol transmembrane transporter activity
0.46	GO:0005372	water transmembrane transporter activity
0.44	GO:0015204	urea transmembrane transporter activity
0.43	GO:0015105	arsenite transmembrane transporter activity

0.52	GO:0016323	basolateral plasma membrane
0.49	GO:0005911	cell-cell junction
0.43	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.34	GO:0046930	pore complex
0.33	GO:0005887	integral component of plasma membrane

sp|Q803U7|EXO1_DANRE
Exonuclease 1
Search

EXO1

0.91	Exonuclease 1

0.65	GO:0006281	DNA repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.57	GO:0016446	somatic hypermutation of immunoglobulin genes
0.56	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response
0.56	GO:0002312	B cell activation involved in immune response
0.55	GO:0002455	humoral immune response mediated by circulating immunoglobulin
0.36	GO:0051321	meiotic cell cycle
0.36	GO:0000732	strand displacement
0.36	GO:0001325	formation of extrachromosomal circular DNA
0.36	GO:0090737	telomere maintenance via telomere trimming

0.84	GO:0035312	5'-3' exodeoxyribonuclease activity
0.56	GO:0008297	single-stranded DNA exodeoxyribonuclease activity
0.56	GO:0008309	double-stranded DNA exodeoxyribonuclease activity
0.55	GO:0048256	flap endonuclease activity
0.54	GO:0003677	DNA binding
0.51	GO:0003682	chromatin binding
0.35	GO:0046872	metal ion binding
0.34	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.33	GO:0005515	protein binding

0.59	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.42	GO:0005886	plasma membrane
0.33	GO:0005739	mitochondrion

0.34

EC:3.1.26.4

GO:0004523

tr|Q803V2|Q803V2_DANRE
Phosphoribosyl pyrophosphate synthetase-associated protein 2
Search

PRPSAP2

0.96	Phosphoribosyl pyrophosphate synthetase-associated protein 2

0.62	GO:0009165	nucleotide biosynthetic process
0.62	GO:0009116	nucleoside metabolic process
0.44	GO:0060348	bone development
0.34	GO:0043086	negative regulation of catalytic activity
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.76	GO:0004749	ribose phosphate diphosphokinase activity
0.63	GO:0000287	magnesium ion binding
0.34	GO:0005515	protein binding
0.34	GO:0004857	enzyme inhibitor activity
0.33	GO:0003735	structural constituent of ribosome

0.37	GO:0002189	ribose phosphate diphosphokinase complex
0.34	GO:0043234	protein complex
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.76	EC:2.7.6.1	GO:0004749
0.76	KEGG:R01049	GO:0004749

sp|Q803V3|P2R3C_DANRE
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma
Search

PPP2R3C

0.96	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma

0.84	GO:0045579	positive regulation of B cell differentiation
0.83	GO:0001782	B cell homeostasis
0.82	GO:0043029	T cell homeostasis
0.77	GO:0051900	regulation of mitochondrial depolarization
0.76	GO:0002759	regulation of antimicrobial humoral response
0.76	GO:0048536	spleen development
0.70	GO:0032147	activation of protein kinase activity
0.63	GO:0030865	cortical cytoskeleton organization
0.59	GO:0000226	microtubule cytoskeleton organization

0.47	GO:0005509	calcium ion binding
0.37	GO:0005515	protein binding

0.74	GO:0005813	centrosome
0.63	GO:0005794	Golgi apparatus
0.61	GO:0005829	cytosol
0.59	GO:0005819	spindle
0.56	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q803V5|LST8_DANRE
Target of rapamycin complex subunit lst8
Search

MLST8

0.93	Target of rapamycin complex subunit lst8

0.82	GO:0031929	TOR signaling
0.81	GO:0032008	positive regulation of TOR signaling
0.54	GO:0032956	regulation of actin cytoskeleton organization
0.53	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.52	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.51	GO:0032273	positive regulation of protein polymerization
0.51	GO:1902905	positive regulation of supramolecular fiber organization
0.51	GO:0051495	positive regulation of cytoskeleton organization
0.50	GO:0032535	regulation of cellular component size
0.49	GO:0043087	regulation of GTPase activity

0.54	GO:0043539	protein serine/threonine kinase activator activity
0.33	GO:0005515	protein binding

0.83	GO:0031931	TORC1 complex
0.82	GO:0031932	TORC2 complex
0.35	GO:0005829	cytosol
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|Q803V7|Q803V7_DANRE
Cell division cycle 34 homolog (S. cerevisiae) a
Search

0.69	Ubiquitin-conjugating enzyme E2

0.57	GO:0070936	protein K48-linked ubiquitination
0.52	GO:0043951	negative regulation of cAMP-mediated signaling
0.52	GO:0035458	cellular response to interferon-beta
0.51	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.47	GO:0006513	protein monoubiquitination
0.43	GO:0051301	cell division
0.38	GO:0090261	positive regulation of inclusion body assembly
0.38	GO:0043525	positive regulation of neuron apoptotic process
0.36	GO:0070848	response to growth factor
0.34	GO:2000403	positive regulation of lymphocyte migration

0.57	GO:0061631	ubiquitin conjugating enzyme activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0061630	ubiquitin protein ligase activity
0.35	GO:0098640	integrin binding involved in cell-matrix adhesion

0.49	GO:0016607	nuclear speck
0.45	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|Q803W0|Q803W0_DANRE
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Ab
Search

0.94	DECD-box RNA helicase

0.52	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.50	GO:0051028	mRNA transport
0.50	GO:0006405	RNA export from nucleus
0.49	GO:0000398	mRNA splicing, via spliceosome
0.49	GO:0010501	RNA secondary structure unwinding
0.42	GO:0046784	viral mRNA export from host cell nucleus
0.42	GO:2000002	negative regulation of DNA damage checkpoint
0.41	GO:0006974	cellular response to DNA damage stimulus
0.40	GO:0032786	positive regulation of DNA-templated transcription, elongation
0.39	GO:0022618	ribonucleoprotein complex assembly

0.56	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.46	GO:0042802	identical protein binding
0.46	GO:0008186	RNA-dependent ATPase activity
0.42	GO:0043008	ATP-dependent protein binding
0.41	GO:0140098	catalytic activity, acting on RNA

0.49	GO:0016607	nuclear speck
0.46	GO:0005681	spliceosomal complex
0.43	GO:0005730	nucleolus
0.41	GO:0005687	U4 snRNP
0.41	GO:0000346	transcription export complex
0.41	GO:0005688	U6 snRNP
0.38	GO:0005737	cytoplasm
0.36	GO:0005700	polytene chromosome
0.30	GO:0016020	membrane

sp|Q803W1|SCRN3_DANRE
Secernin-3
Search

SCRN3

0.97	Secernin-3

0.61	GO:0006508	proteolysis
0.46	GO:0006887	exocytosis
0.33	GO:0006099	tricarboxylic acid cycle

0.77	GO:0016805	dipeptidase activity
0.33	GO:0004108	citrate (Si)-synthase activity

0.77

EC:3.4.13

GO:0016805

sp|Q803X0|SERC5_DANRE
Serine incorporator 5
Search

SERINC5

0.95	Serine incorporator 5

0.82	GO:0006658	phosphatidylserine metabolic process
0.81	GO:0042552	myelination
0.76	GO:0006665	sphingolipid metabolic process
0.56	GO:0009597	detection of virus
0.50	GO:0045087	innate immune response
0.50	GO:0015825	L-serine transport
0.50	GO:0051607	defense response to virus
0.39	GO:1904219	positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity
0.39	GO:1904222	positive regulation of serine C-palmitoyltransferase activity
0.37	GO:0008654	phospholipid biosynthetic process

0.50	GO:0015194	L-serine transmembrane transporter activity
0.34	GO:0030674	protein binding, bridging
0.33	GO:0051537	2 iron, 2 sulfur cluster binding
0.33	GO:0004003	ATP-dependent DNA helicase activity
0.32	GO:0003677	DNA binding

0.51	GO:0043209	myelin sheath
0.47	GO:0005794	Golgi apparatus
0.41	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0034998	oligosaccharyltransferase I complex
0.34	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q803X1|CTU1_DANRE
Cytoplasmic tRNA 2-thiolation protein 1
Search

0.71	Cytoplasmic tRNA 2-thiolation protein 1

0.81	GO:0032447	protein urmylation
0.78	GO:0034227	tRNA thio-modification
0.76	GO:0002098	tRNA wobble uridine modification
0.35	GO:0007160	cell-matrix adhesion

0.68	GO:0000049	tRNA binding
0.61	GO:0016779	nucleotidyltransferase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0046872	metal ion binding

0.48	GO:0005737	cytoplasm
0.36	GO:0043234	protein complex
0.34	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane

0.61

GO:0016779

sp|Q803X4|DCA13_DANRE
DDB1- and CUL4-associated factor 13
Search

DCAF13

0.91	WD repeat and SOF domain-containing protein 1

0.65	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.48	GO:0016567	protein ubiquitination
0.38	GO:0043687	post-translational protein modification
0.37	GO:0016573	histone acetylation

0.48	GO:0030331	estrogen receptor binding
0.38	GO:0003723	RNA binding
0.38	GO:0004402	histone acetyltransferase activity

0.73	GO:0005730	nucleolus
0.71	GO:0005813	centrosome
0.70	GO:0080008	Cul4-RING E3 ubiquitin ligase complex
0.68	GO:0030054	cell junction
0.64	GO:0032040	small-subunit processome
0.63	GO:0005829	cytosol
0.37	GO:0005654	nucleoplasm

0.38

GO:0004402

tr|Q803Y0|Q803Y0_DANRE
Calcineurin-like EF-hand protein 2
Search

CHP1

0.85	Calcineurin B like proteinous protein 1

0.58	GO:0070884	regulation of calcineurin-NFAT signaling cascade
0.56	GO:0032417	positive regulation of sodium:proton antiporter activity
0.56	GO:0106057	negative regulation of calcineurin-mediated signaling
0.55	GO:0042306	regulation of protein import into nucleus
0.53	GO:0010921	regulation of phosphatase activity
0.53	GO:1904590	negative regulation of protein import
0.53	GO:0046823	negative regulation of nucleocytoplasmic transport
0.53	GO:1900181	negative regulation of protein localization to nucleus
0.53	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.52	GO:0051453	regulation of intracellular pH

0.70	GO:0005509	calcium ion binding
0.53	GO:0048306	calcium-dependent protein binding
0.40	GO:0004860	protein kinase inhibitor activity
0.40	GO:0019900	kinase binding
0.39	GO:0008017	microtubule binding
0.35	GO:0005215	transporter activity
0.35	GO:0015459	potassium channel regulator activity

0.42	GO:0005886	plasma membrane
0.40	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.40	GO:0005634	nucleus
0.40	GO:0030133	transport vesicle
0.39	GO:0000139	Golgi membrane
0.38	GO:0015630	microtubule cytoskeleton
0.38	GO:0005783	endoplasmic reticulum
0.36	GO:0005829	cytosol
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome

sp|Q803Y4|UFM1_DANRE
Ubiquitin-fold modifier 1
Search

UFM1

0.89	Ubiquitin-fold modifier 1

0.86	GO:0071569	protein ufmylation
0.71	GO:0033146	regulation of intracellular estrogen receptor signaling pathway
0.69	GO:0034976	response to endoplasmic reticulum stress
0.44	GO:0043066	negative regulation of apoptotic process
0.39	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus
0.33	GO:0055114	oxidation-reduction process

0.38	GO:0005515	protein binding
0.35	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.61	GO:0005634	nucleus
0.57	GO:0005783	endoplasmic reticulum
0.42	GO:0070062	extracellular exosome

0.35

GO:0016620

sp|Q803Z2|YIPF3_DANRE
Protein YIPF3
Search

YIPF3

0.97	Yip1 domain family member 3

0.67	GO:0030133	transport vesicle
0.63	GO:0005794	Golgi apparatus
0.30	GO:0044425	membrane part

tr|Q803Z6|Q803Z6_DANRE
Bagpipe homeobox transcription factor Bapx1
Search

NKX3-2

0.87	Homeobox protein zampogna

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0048706	embryonic skeletal system development
0.48	GO:0048705	skeletal system morphogenesis
0.48	GO:0048562	embryonic organ morphogenesis
0.46	GO:1904888	cranial skeletal system development
0.42	GO:0009888	tissue development
0.42	GO:0035295	tube development
0.41	GO:0051093	negative regulation of developmental process

0.64	GO:0043565	sequence-specific DNA binding
0.42	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.41	GO:0044212	transcription regulatory region DNA binding
0.40	GO:0003690	double-stranded DNA binding
0.39	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.39	GO:0097162	MADS box domain binding
0.39	GO:0030284	estrogen receptor activity
0.39	GO:0030331	estrogen receptor binding
0.38	GO:0043621	protein self-association
0.38	GO:0042826	histone deacetylase binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

EC:3.5.4.4

GO:0004000

tr|Q804C0|Q804C0_DANRE
Neuronal calcium sensor 1
Search

NCS1

0.96	Neuronal calcium sensor 1

0.42	GO:0048731	system development
0.41	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.41	GO:0010446	response to alkaline pH
0.41	GO:1905949	negative regulation of calcium ion import across plasma membrane
0.41	GO:0051960	regulation of nervous system development
0.41	GO:0060284	regulation of cell development
0.41	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.40	GO:0070588	calcium ion transmembrane transport
0.40	GO:0007635	chemosensory behavior
0.39	GO:0030154	cell differentiation

0.70	GO:0005509	calcium ion binding
0.42	GO:0005245	voltage-gated calcium channel activity
0.41	GO:0098744	1-phosphatidylinositol 4-kinase activator activity
0.38	GO:0019901	protein kinase binding
0.36	GO:0000287	magnesium ion binding
0.35	GO:0008427	calcium-dependent protein kinase inhibitor activity
0.35	GO:0016301	kinase activity

0.52	GO:0036477	somatodendritic compartment
0.50	GO:0030424	axon
0.48	GO:0120038	plasma membrane bounded cell projection part
0.42	GO:0043231	intracellular membrane-bounded organelle
0.42	GO:0005886	plasma membrane
0.41	GO:0014069	postsynaptic density
0.41	GO:0012505	endomembrane system
0.40	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0044297	cell body
0.39	GO:0030054	cell junction

tr|Q804G7|Q804G7_DANRE
Annexin
Search

ANXA4

0.63

Annexin

0.54	GO:2000483	negative regulation of interleukin-8 secretion
0.52	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.52	GO:0007219	Notch signaling pathway
0.49	GO:0030855	epithelial cell differentiation
0.46	GO:0006357	regulation of transcription by RNA polymerase II
0.46	GO:0050819	negative regulation of coagulation
0.35	GO:0001822	kidney development
0.34	GO:0043066	negative regulation of apoptotic process
0.34	GO:0006887	exocytosis
0.34	GO:0043086	negative regulation of catalytic activity

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.53	GO:0051059	NF-kappaB binding
0.52	GO:0048306	calcium-dependent protein binding
0.47	GO:0042802	identical protein binding
0.35	GO:0035374	chondroitin sulfate binding
0.35	GO:0004859	phospholipase inhibitor activity
0.35	GO:0008201	heparin binding
0.34	GO:0030246	carbohydrate binding

0.49	GO:0031965	nuclear membrane
0.49	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0012506	vesicle membrane
0.48	GO:0009986	cell surface
0.40	GO:0005886	plasma membrane
0.38	GO:0070062	extracellular exosome
0.36	GO:0045177	apical part of cell
0.35	GO:0042583	chromaffin granule
0.34	GO:0044433	cytoplasmic vesicle part
0.34	GO:0098805	whole membrane

tr|Q804H0|Q804H0_DANRE
Annexin
Search

ANXA1

0.61

Annexin

0.67	GO:0043086	negative regulation of catalytic activity
0.60	GO:2000483	negative regulation of interleukin-8 secretion
0.59	GO:0045629	negative regulation of T-helper 2 cell differentiation
0.59	GO:0045627	positive regulation of T-helper 1 cell differentiation
0.58	GO:0014839	myoblast migration involved in skeletal muscle regeneration
0.57	GO:0002548	monocyte chemotaxis
0.57	GO:0045920	negative regulation of exocytosis
0.57	GO:0097350	neutrophil clearance
0.57	GO:0032743	positive regulation of interleukin-2 production
0.57	GO:0071385	cellular response to glucocorticoid stimulus

0.81	GO:0005544	calcium-dependent phospholipid binding
0.81	GO:0004859	phospholipase inhibitor activity
0.70	GO:0005509	calcium ion binding
0.57	GO:0048306	calcium-dependent protein binding
0.56	GO:0098641	cadherin binding involved in cell-cell adhesion
0.52	GO:0030674	protein binding, bridging
0.44	GO:0005198	structural molecule activity
0.42	GO:0051059	NF-kappaB binding
0.42	GO:0042802	identical protein binding
0.41	GO:0033676	double-stranded DNA-dependent ATPase activity

0.59	GO:0031232	extrinsic component of external side of plasma membrane
0.56	GO:0016328	lateral plasma membrane
0.55	GO:0001533	cornified envelope
0.54	GO:0070062	extracellular exosome
0.54	GO:0016324	apical plasma membrane
0.53	GO:0042383	sarcolemma
0.53	GO:0005913	cell-cell adherens junction
0.53	GO:0031514	motile cilium
0.53	GO:0005884	actin filament
0.51	GO:0005768	endosome

tr|Q804Q4|Q804Q4_DANRE
Leftover
Search

0.95	Potassium channel tetramerization domain containing 12

0.77	GO:0051260	protein homooligomerization
0.54	GO:0021986	habenula development
0.51	GO:0048814	regulation of dendrite morphogenesis
0.42	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway

0.37

GO:0042802

identical protein binding

0.40	GO:0043235	receptor complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q804Q5|FEZF2_DANRE
Fez family zinc finger protein 2
Search

FEZF2

0.95	Testis tissue sperm-binding protein Li 80P

0.53	GO:0021797	forebrain anterior/posterior pattern specification
0.52	GO:0043697	cell dedifferentiation
0.50	GO:0021772	olfactory bulb development
0.50	GO:0001764	neuron migration
0.49	GO:0007411	axon guidance
0.49	GO:0045666	positive regulation of neuron differentiation
0.48	GO:0008285	negative regulation of cell proliferation
0.48	GO:0000122	negative regulation of transcription by RNA polymerase II
0.46	GO:0045893	positive regulation of transcription, DNA-templated
0.39	GO:0021879	forebrain neuron differentiation

0.51	GO:0003676	nucleic acid binding
0.49	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.48	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0046872	metal ion binding
0.36	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.36	GO:0003682	chromatin binding
0.32	GO:0016491	oxidoreductase activity

0.44	GO:0005829	cytosol
0.43	GO:0005634	nucleus

0.32

GO:0016491

tr|Q804R0|Q804R0_DANRE
Ladybird homeobox 2
Search

LBX1

0.97	Ladybird homeobox 1 transcription factor

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0021519	spinal cord association neuron specification
0.52	GO:0048664	neuron fate determination
0.51	GO:0021522	spinal cord motor neuron differentiation
0.51	GO:0002009	morphogenesis of an epithelium
0.50	GO:0035239	tube morphogenesis
0.50	GO:0061371	determination of heart left/right asymmetry
0.50	GO:0045664	regulation of neuron differentiation

0.64	GO:0043565	sequence-specific DNA binding
0.42	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.30	GO:0016021	integral component of membrane

sp|Q804S5|MIB1_DANRE
E3 ubiquitin-protein ligase mib1
Search

MIB1

0.93	Mindbomb E3 ubiquitin protein ligase 1

0.73	GO:0016567	protein ubiquitination
0.63	GO:0001947	heart looping
0.63	GO:0001756	somitogenesis
0.63	GO:0001841	neural tube formation
0.62	GO:0007219	Notch signaling pathway
0.62	GO:0045807	positive regulation of endocytosis
0.62	GO:0045665	negative regulation of neuron differentiation
0.60	GO:0001568	blood vessel development
0.58	GO:0001701	in utero embryonic development
0.46	GO:0006897	endocytosis

0.73	GO:0004842	ubiquitin-protein transferase activity
0.62	GO:0008270	zinc ion binding
0.50	GO:0016874	ligase activity

0.59	GO:0005813	centrosome
0.55	GO:0031410	cytoplasmic vesicle
0.37	GO:0014069	postsynaptic density
0.34	GO:0030529	intracellular ribonucleoprotein complex

0.50	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

sp|Q804S6|EMX1_DANRE
Homeobox protein EMX1
Search

EMX2

0.90	Empty spiracles homeobox 1

0.64	GO:0007420	brain development
0.63	GO:0030182	neuron differentiation
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0003002	regionalization
0.55	GO:0061351	neural precursor cell proliferation
0.55	GO:0120036	plasma membrane bounded cell projection organization
0.54	GO:0048468	cell development
0.54	GO:0000902	cell morphogenesis

0.64

GO:0043565

sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0044446	intracellular organelle part

sp|Q804T6|DIX1A_DANRE
Dixin-A
Search

DIXDC1

0.88	DIX domain containing 1

0.77	GO:0016055	Wnt signaling pathway
0.41	GO:0030177	positive regulation of Wnt signaling pathway
0.41	GO:0030900	forebrain development
0.38	GO:0043010	camera-type eye development
0.38	GO:0061351	neural precursor cell proliferation
0.37	GO:0045665	negative regulation of neuron differentiation
0.37	GO:0060828	regulation of canonical Wnt signaling pathway
0.37	GO:0070507	regulation of microtubule cytoskeleton organization
0.37	GO:0016477	cell migration
0.37	GO:0032956	regulation of actin cytoskeleton organization

0.37	GO:0043015	gamma-tubulin binding
0.37	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.37	GO:0019904	protein domain specific binding
0.35	GO:0003779	actin binding
0.33	GO:0004742	dihydrolipoyllysine-residue acetyltransferase activity

0.40	GO:0005925	focal adhesion
0.39	GO:0005829	cytosol
0.36	GO:0043679	axon terminus
0.36	GO:0043025	neuronal cell body
0.34	GO:0043234	protein complex
0.33	GO:0045254	pyruvate dehydrogenase complex
0.33	GO:0005759	mitochondrial matrix

0.33

EC:2.3.1.12

GO:0004742

tr|Q804W1|Q804W1_DANRE
Parvalbumin 6
Search

0.92	Parvalbumin alpha

0.33	GO:0045893	positive regulation of transcription, DNA-templated
0.32	GO:0023052	signaling

0.70	GO:0005509	calcium ion binding
0.33	GO:0043565	sequence-specific DNA binding

0.42	GO:0030424	axon
0.35	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus

sp|Q804W2|PRV7_DANRE
Parvalbumin-7
Search

0.91	Parvalbumin alpha

0.37	GO:0051480	regulation of cytosolic calcium ion concentration
0.34	GO:0045893	positive regulation of transcription, DNA-templated
0.32	GO:0023052	signaling

0.70	GO:0005509	calcium ion binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0046982	protein heterodimerization activity
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0030424	axon
0.37	GO:0043679	axon terminus
0.37	GO:0043025	neuronal cell body
0.35	GO:0005737	cytoplasm
0.35	GO:0005634	nucleus
0.34	GO:0070062	extracellular exosome
0.34	GO:0043234	protein complex

sp|Q805B2|FGF8B_DANRE
Fibroblast growth factor 8b
Search

0.62	Fibroblast growth factor

0.79	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.55	GO:0030917	midbrain-hindbrain boundary development
0.55	GO:0030916	otic vesicle formation
0.54	GO:0030878	thyroid gland development
0.54	GO:0060037	pharyngeal system development
0.53	GO:0090133	mesendoderm migration
0.53	GO:0060128	corticotropin hormone secreting cell differentiation
0.53	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation
0.52	GO:0048634	regulation of muscle organ development

0.81	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.36	GO:0042056	chemoattractant activity
0.35	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.34	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0004713	protein tyrosine kinase activity

0.63	GO:0005576	extracellular region
0.40	GO:0005764	lysosome
0.35	GO:0009897	external side of plasma membrane
0.30	GO:0016021	integral component of membrane

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

sp|Q805E5|CHSTE_DANRE
Carbohydrate sulfotransferase 14
Search

CHST14

0.66	Carbohydrate sulfotransferase

0.66	GO:0016051	carbohydrate biosynthetic process
0.55	GO:0050655	dermatan sulfate proteoglycan metabolic process
0.39	GO:0030166	proteoglycan biosynthetic process
0.39	GO:1903510	mucopolysaccharide metabolic process
0.37	GO:0006024	glycosaminoglycan biosynthetic process
0.36	GO:0044272	sulfur compound biosynthetic process
0.36	GO:0050654	chondroitin sulfate proteoglycan metabolic process
0.35	GO:0072330	monocarboxylic acid biosynthetic process
0.34	GO:0017144	drug metabolic process

0.77	GO:0008146	sulfotransferase activity
0.35	GO:0042301	phosphate ion binding
0.33	GO:0005515	protein binding

0.73	GO:0000139	Golgi membrane
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.77

GO:0008146

tr|Q8AV10|Q8AV10_DANRE
Chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)
Search

0.97	Chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.68	GO:0006952	defense response
0.66	GO:0021730	trigeminal sensory nucleus development
0.66	GO:0097534	lymphoid lineage cell migration
0.64	GO:0050930	induction of positive chemotaxis
0.63	GO:0031290	retinal ganglion cell axon guidance
0.62	GO:0042074	cell migration involved in gastrulation
0.62	GO:0050918	positive chemotaxis
0.61	GO:0001764	neuron migration

0.84	GO:0008009	chemokine activity
0.63	GO:0042056	chemoattractant activity
0.48	GO:0045236	CXCR chemokine receptor binding

0.66	GO:0005576	extracellular region
0.45	GO:0009897	external side of plasma membrane

tr|Q8AV60|Q8AV60_DANRE
Insulin-induced gene protein
Search

INSIG2

0.94	Insulin-induced gene protein (Fragment)

0.83	GO:0008203	cholesterol metabolic process
0.63	GO:0060363	cranial suture morphogenesis
0.62	GO:0042474	middle ear morphogenesis
0.62	GO:0010894	negative regulation of steroid biosynthetic process
0.61	GO:0006991	response to sterol depletion
0.60	GO:0006984	ER-nucleus signaling pathway
0.60	GO:0060021	palate development
0.59	GO:0045717	negative regulation of fatty acid biosynthetic process
0.59	GO:0042472	inner ear morphogenesis
0.58	GO:0006641	triglyceride metabolic process

0.37

GO:0008134

transcription factor binding

0.69	GO:0005789	endoplasmic reticulum membrane
0.47	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q8AV61|INSI1_DANRE
Insulin-induced gene 1 protein
Search

INSIG1

0.94	Insulin-induced gene protein (Fragment)

0.83	GO:0008203	cholesterol metabolic process
0.61	GO:0060363	cranial suture morphogenesis
0.60	GO:0042474	middle ear morphogenesis
0.59	GO:0010894	negative regulation of steroid biosynthetic process
0.58	GO:0006991	response to sterol depletion
0.58	GO:0060021	palate development
0.58	GO:0006984	ER-nucleus signaling pathway
0.57	GO:0045717	negative regulation of fatty acid biosynthetic process
0.57	GO:0036316	SREBP-SCAP complex retention in endoplasmic reticulum
0.57	GO:1901303	negative regulation of cargo loading into COPII-coated vesicle

0.35

GO:0008134

transcription factor binding

0.65	GO:0005789	endoplasmic reticulum membrane
0.46	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

tr|Q8AV68|Q8AV68_DANRE
Cholinergic receptor, nicotinic, beta 3b (neuronal)
Search

0.92	Cholinergic receptor nicotinic beta 3 subunit

0.78	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.52	GO:0035094	response to nicotine
0.51	GO:0007271	synaptic transmission, cholinergic
0.51	GO:0007274	neuromuscular synaptic transmission
0.41	GO:0006812	cation transport

0.81	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.52	GO:0042166	acetylcholine binding

0.78	GO:0045211	postsynaptic membrane
0.73	GO:0030054	cell junction
0.51	GO:0005892	acetylcholine-gated channel complex

tr|Q8AV71|Q8AV71_DANRE
Homeobox protein Ved
Search

0.96	Ventrally expressed dharma/bozozok antagonist

0.55	GO:0042663	regulation of endodermal cell fate specification
0.54	GO:0042661	regulation of mesodermal cell fate specification
0.54	GO:0007275	multicellular organism development
0.53	GO:2001141	regulation of RNA biosynthetic process
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.49	GO:0060061	Spemann organizer formation
0.48	GO:0036342	post-anal tail morphogenesis
0.45	GO:0045165	cell fate commitment
0.45	GO:0120039	plasma membrane bounded cell projection morphogenesis

0.59	GO:0043565	sequence-specific DNA binding
0.41	GO:0042803	protein homodimerization activity
0.41	GO:0035326	enhancer binding
0.40	GO:0046982	protein heterodimerization activity
0.40	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.39	GO:0001012	RNA polymerase II regulatory region DNA binding
0.38	GO:0003690	double-stranded DNA binding
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0003887	DNA-directed DNA polymerase activity
0.34	GO:0016301	kinase activity

0.61

GO:0005634

nucleus

0.35

EC:2.7.7.7

GO:0003887

tr|Q8AVB1|Q8AVB1_DANRE
Slow troponin T
Search

0.89	Low Mr mutant cardiac troponin T

0.83	GO:0006937	regulation of muscle contraction
0.49	GO:0006941	striated muscle contraction
0.46	GO:0061061	muscle structure development
0.45	GO:0043462	regulation of ATPase activity
0.44	GO:0050881	musculoskeletal movement
0.44	GO:0030029	actin filament-based process
0.43	GO:0010927	cellular component assembly involved in morphogenesis
0.43	GO:0003229	ventricular cardiac muscle tissue development
0.43	GO:0003208	cardiac ventricle morphogenesis
0.43	GO:0060047	heart contraction

0.50	GO:0030172	troponin C binding
0.50	GO:0031013	troponin I binding
0.48	GO:0005523	tropomyosin binding
0.46	GO:0030899	calcium-dependent ATPase activity
0.44	GO:0048306	calcium-dependent protein binding
0.44	GO:0003779	actin binding
0.33	GO:0005198	structural molecule activity
0.33	GO:0030674	protein binding, bridging
0.32	GO:0046872	metal ion binding

0.84	GO:0005861	troponin complex
0.42	GO:0097512	cardiac myofibril
0.33	GO:0005840	ribosome
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|Q8AW07|Q8AW07_DANRE
Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12
Search

PSMD12

0.88	26S proteasome non-ATPase regulatory subunit 12

0.47	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.47	GO:1904888	cranial skeletal system development
0.46	GO:0001822	kidney development
0.45	GO:0007420	brain development
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.36	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.36	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation

0.69	GO:1905369	endopeptidase complex
0.57	GO:0043234	protein complex
0.44	GO:0031981	nuclear lumen
0.37	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0097708	intracellular vesicle
0.34	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

tr|Q8AW33|Q8AW33_DANRE
SI:dZ182N13.3 (Novel troponin I) (Fragment)
Search

TNNI1

0.89	LOW QUALITY PROTEIN: troponin I, slow skeletal muscle

0.53	GO:0014883	transition between fast and slow fiber
0.51	GO:0007507	heart development
0.51	GO:0060415	muscle tissue morphogenesis
0.49	GO:0014706	striated muscle tissue development
0.45	GO:0003009	skeletal muscle contraction
0.45	GO:0060048	cardiac muscle contraction
0.36	GO:0006937	regulation of muscle contraction
0.35	GO:1901876	regulation of calcium ion binding
0.35	GO:0030049	muscle filament sliding

0.37	GO:0003779	actin binding
0.34	GO:0046872	metal ion binding

0.81	GO:0005861	troponin complex
0.33	GO:0005829	cytosol

sp|Q8AW35|PHLA3_DANRE
Pleckstrin homology-like domain family A member 3
Search

PHLDA2

0.92	Pleckstrin homology like domain family A member 3

0.72	GO:1903547	regulation of growth hormone activity
0.71	GO:0060723	regulation of cell proliferation involved in embryonic placenta development
0.67	GO:0045210	FasL biosynthetic process
0.66	GO:0070873	regulation of glycogen metabolic process
0.64	GO:0001890	placenta development
0.62	GO:0048638	regulation of developmental growth
0.61	GO:0030334	regulation of cell migration
0.60	GO:0009887	animal organ morphogenesis
0.54	GO:0006915	apoptotic process
0.54	GO:0051898	negative regulation of protein kinase B signaling

0.55	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.54	GO:0010314	phosphatidylinositol-5-phosphate binding
0.54	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.53	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.53	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.52	GO:0032266	phosphatidylinositol-3-phosphate binding
0.36	GO:0005515	protein binding

0.55	GO:0005730	nucleolus
0.46	GO:0005861	troponin complex
0.41	GO:0005886	plasma membrane
0.40	GO:0031410	cytoplasmic vesicle
0.35	GO:0005829	cytosol

sp|Q8AW42|S39AD_DANRE
Zinc transporter ZIP13
Search

SLC39A13

0.90	Solute carrier family 39 (Metal ion transporter), member 13

0.66	GO:0030001	metal ion transport
0.55	GO:0055085	transmembrane transport
0.54	GO:0006882	cellular zinc ion homeostasis
0.50	GO:0061448	connective tissue development
0.48	GO:0072511	divalent inorganic cation transport
0.39	GO:0010043	response to zinc ion
0.36	GO:0060586	multicellular organismal iron ion homeostasis
0.36	GO:0097501	stress response to metal ion
0.34	GO:0098754	detoxification

0.69	GO:0046873	metal ion transmembrane transporter activity
0.50	GO:0072509	divalent inorganic cation transmembrane transporter activity
0.47	GO:0042803	protein homodimerization activity

0.49	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005794	Golgi apparatus
0.38	GO:0098588	bounding membrane of organelle
0.38	GO:0031984	organelle subcompartment
0.37	GO:0005783	endoplasmic reticulum
0.35	GO:0016323	basolateral plasma membrane
0.34	GO:0031301	integral component of organelle membrane

sp|Q8AW52|ATOH7_DANRE
Protein atonal homolog 7
Search

ATOH7

0.97	Atonal bHLH transcription factor 7

0.77	GO:0007423	sensory organ development
0.62	GO:0007399	nervous system development
0.59	GO:0060563	neuroepithelial cell differentiation
0.57	GO:0009913	epidermal cell differentiation
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0045165	cell fate commitment
0.54	GO:0009649	entrainment of circadian clock
0.51	GO:0007623	circadian rhythm

0.68	GO:0046983	protein dimerization activity
0.48	GO:0043565	sequence-specific DNA binding
0.47	GO:0003682	chromatin binding
0.45	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.44	GO:0001012	RNA polymerase II regulatory region DNA binding
0.42	GO:0003690	double-stranded DNA binding
0.30	GO:0003824	catalytic activity

0.41

GO:0005634

nucleus

tr|Q8AW58|Q8AW58_DANRE
G2/M-phase-specific E3 ubiquitin protein ligase
Search

G2E3

0.91	G2/M-phase-specific E3 ubiquitin protein ligase

0.70	GO:0016567	protein ubiquitination
0.38	GO:0006915	apoptotic process
0.38	GO:0007275	multicellular organism development
0.37	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway

0.71	GO:0004842	ubiquitin-protein transferase activity
0.53	GO:0016874	ligase activity
0.53	GO:0046872	metal ion binding
0.36	GO:0061659	ubiquitin-like protein ligase activity
0.33	GO:0005515	protein binding

0.49	GO:0005829	cytosol
0.43	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0044446	intracellular organelle part

0.53	EC:6	GO:0016874
0.71	KEGG:R03876	GO:0004842

tr|Q8AWD0|Q8AWD0_DANRE
Vdac2 protein
Search

VDAC2

0.91	Voltage-dependent anion channel

0.69	GO:0098656	anion transmembrane transport
0.52	GO:0007339	binding of sperm to zona pellucida
0.51	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.50	GO:0032272	negative regulation of protein polymerization
0.45	GO:0031101	fin regeneration
0.45	GO:0036444	mitochondrial calcium uptake
0.43	GO:0008016	regulation of heart contraction
0.35	GO:0015866	ADP transport
0.33	GO:0006754	ATP biosynthetic process
0.32	GO:0006412	translation

0.77	GO:0008308	voltage-gated anion channel activity
0.41	GO:0042803	protein homodimerization activity
0.40	GO:0015288	porin activity
0.35	GO:1901265	nucleoside phosphate binding
0.35	GO:0036094	small molecule binding
0.33	GO:0003735	structural constituent of ribosome

0.77	GO:0005741	mitochondrial outer membrane
0.51	GO:0001669	acrosomal vesicle
0.51	GO:0042645	mitochondrial nucleoid
0.50	GO:0043209	myelin sheath
0.42	GO:0005743	mitochondrial inner membrane
0.40	GO:0046930	pore complex
0.38	GO:0070382	exocytic vesicle
0.37	GO:0097458	neuron part
0.37	GO:0043230	extracellular organelle
0.37	GO:0045121	membrane raft

sp|Q8AWD1|M1I1L_DANRE
Mid1-interacting protein 1-like
Search

0.96	Gastrulation-specific protein G12

0.85	GO:0051351	positive regulation of ligase activity
0.84	GO:0045723	positive regulation of fatty acid biosynthetic process
0.83	GO:0007026	negative regulation of microtubule depolymerization
0.73	GO:0051258	protein polymerization
0.44	GO:0006853	carnitine shuttle
0.40	GO:0006629	lipid metabolic process

0.79	GO:0008022	protein C-terminus binding
0.70	GO:0042802	identical protein binding

0.71	GO:0015630	microtubule cytoskeleton
0.65	GO:0005829	cytosol
0.61	GO:0005634	nucleus
0.51	GO:0099513	polymeric cytoskeletal fiber

sp|Q8AWD2|MOCS3_DANRE
Adenylyltransferase and sulfurtransferase MOCS3
Search

MOCS3

0.87	Adenylyltransferase and sulfurtransferase MOCS3

0.79	GO:0098822	peptidyl-cysteine modification to L-cysteine persulfide
0.75	GO:0002143	tRNA wobble position uridine thiolation
0.74	GO:0018307	enzyme active site formation
0.66	GO:0006777	Mo-molybdopterin cofactor biosynthetic process
0.51	GO:0032447	protein urmylation
0.39	GO:2000220	regulation of pseudohyphal growth
0.39	GO:0018117	protein adenylylation
0.39	GO:0001403	invasive growth in response to glucose limitation
0.39	GO:0007114	cell budding
0.37	GO:0034599	cellular response to oxidative stress

0.79	GO:0061604	molybdopterin-synthase sulfurtransferase activity
0.77	GO:0061605	molybdopterin-synthase adenylyltransferase activity
0.74	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.72	GO:0004792	thiosulfate sulfurtransferase activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0046872	metal ion binding
0.39	GO:0070733	protein adenylyltransferase activity
0.37	GO:0042802	identical protein binding

0.63	GO:0005829	cytosol
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.79	EC:2.8.1.11	GO:0061604
0.72	KEGG:R01931	GO:0004792

tr|Q8AWD4|Q8AWD4_DANRE
Tax1 (Human T-cell leukemia virus type I) binding protein 3
Search

TAX1BP3

0.97	Tax interaction protein 1

0.83	GO:2000009	negative regulation of protein localization to cell surface
0.78	GO:0007266	Rho protein signal transduction
0.78	GO:0090630	activation of GTPase activity
0.77	GO:0030178	negative regulation of Wnt signaling pathway
0.74	GO:0008285	negative regulation of cell proliferation
0.58	GO:0060028	convergent extension involved in axis elongation
0.41	GO:0016055	Wnt signaling pathway

0.78	GO:0008013	beta-catenin binding
0.77	GO:0008022	protein C-terminus binding

0.77	GO:0001650	fibrillar center
0.68	GO:0015629	actin cytoskeleton
0.47	GO:0005737	cytoplasm
0.39	GO:0070062	extracellular exosome
0.36	GO:0005886	plasma membrane

tr|Q8AWD7|Q8AWD7_DANRE
ER membrane protein complex subunit 9
Search

EMC9

0.83	ER membrane protein complex subunit 9

0.84

GO:0072546

ER membrane protein complex

tr|Q8AWD9|Q8AWD9_DANRE
Cathepsin D
Search

CTSD

0.88	Cathepsin D enzyme

0.60	GO:0006508	proteolysis
0.48	GO:0003406	retinal pigment epithelium development
0.45	GO:0061061	muscle structure development
0.44	GO:0009617	response to bacterium
0.41	GO:0006914	autophagy
0.39	GO:0030163	protein catabolic process
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0060441	epithelial tube branching involved in lung morphogenesis
0.35	GO:0030574	collagen catabolic process

0.68	GO:0070001	aspartic-type peptidase activity
0.63	GO:0004175	endopeptidase activity
0.34	GO:0042277	peptide binding
0.34	GO:0008234	cysteine-type peptidase activity
0.33	GO:0017171	serine hydrolase activity
0.33	GO:0005515	protein binding

0.74	GO:0005764	lysosome
0.40	GO:0042470	melanosome
0.38	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.36	GO:0045121	membrane raft
0.35	GO:1904724	tertiary granule lumen
0.35	GO:0035580	specific granule lumen
0.35	GO:0031012	extracellular matrix
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0005775	vacuolar lumen

0.34

GO:0008234

tr|Q8AWE0|Q8AWE0_DANRE
Dopamine D2a receptor
Search

DRD2

0.93	Dopamine receptor 2

0.85	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway
0.61	GO:0051967	negative regulation of synaptic transmission, glutamatergic
0.60	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway
0.60	GO:0048148	behavioral response to cocaine
0.60	GO:0014059	regulation of dopamine secretion
0.59	GO:0048149	behavioral response to ethanol
0.58	GO:0051944	positive regulation of catecholamine uptake involved in synaptic transmission
0.58	GO:1900166	regulation of glial cell-derived neurotrophic factor secretion
0.58	GO:0060160	negative regulation of dopamine receptor signaling pathway
0.58	GO:0035815	positive regulation of renal sodium excretion

0.85	GO:0004952	dopamine neurotransmitter receptor activity
0.60	GO:0035240	dopamine binding
0.49	GO:0042802	identical protein binding
0.48	GO:0004935	adrenergic receptor activity
0.40	GO:0035255	ionotropic glutamate receptor binding
0.37	GO:0046982	protein heterodimerization activity
0.35	GO:0015459	potassium channel regulator activity

0.66	GO:0005887	integral component of plasma membrane
0.54	GO:0060170	ciliary membrane
0.53	GO:0097458	neuron part
0.53	GO:0097730	non-motile cilium
0.49	GO:0099501	exocytic vesicle membrane
0.45	GO:0044456	synapse part
0.39	GO:0016328	lateral plasma membrane
0.39	GO:0036126	sperm flagellum
0.39	GO:0001669	acrosomal vesicle
0.39	GO:0032279	asymmetric synapse

tr|Q8AWR7|Q8AWR7_DANRE
Mothers against decapentaplegic homolog
Search

SMAD7

0.61	Mothers against decapentaplegic homolog

0.74	GO:0007179	transforming growth factor beta receptor signaling pathway
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.53	GO:0006351	transcription, DNA-templated
0.48	GO:0034616	response to laminar fluid shear stress
0.48	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation
0.47	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.47	GO:0032925	regulation of activin receptor signaling pathway
0.47	GO:0051444	negative regulation of ubiquitin-protein transferase activity

0.56	GO:0003700	DNA binding transcription factor activity
0.51	GO:0003677	DNA binding
0.49	GO:0030617	transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
0.48	GO:0048185	activin binding
0.48	GO:0070411	I-SMAD binding
0.48	GO:0034713	type I transforming growth factor beta receptor binding
0.46	GO:0008013	beta-catenin binding
0.45	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0005518	collagen binding
0.44	GO:0001067	regulatory region nucleic acid binding

0.67	GO:0005667	transcription factor complex
0.56	GO:0005634	nucleus
0.47	GO:0016342	catenin complex
0.46	GO:0005913	cell-cell adherens junction
0.46	GO:0005737	cytoplasm
0.44	GO:0005813	centrosome
0.41	GO:0070013	intracellular organelle lumen
0.36	GO:0097708	intracellular vesicle
0.35	GO:0012505	endomembrane system
0.30	GO:0016021	integral component of membrane

sp|Q8AWW7|RUVB1_DANRE
RuvB-like 1
Search

RUVBL1

0.66	RuvB-like helicase

0.70	GO:0032392	DNA geometric change
0.63	GO:0006281	DNA repair
0.62	GO:0006310	DNA recombination
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0016569	covalent chromatin modification
0.55	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.54	GO:1903146	regulation of autophagy of mitochondrion

0.81	GO:0043141	ATP-dependent 5'-3' DNA helicase activity
0.55	GO:0001094	TFIID-class transcription factor binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0051117	ATPase binding
0.52	GO:0045296	cadherin binding

0.83	GO:0097255	R2TP complex
0.79	GO:0035267	NuA4 histone acetyltransferase complex
0.79	GO:0031011	Ino80 complex
0.56	GO:0000812	Swr1 complex
0.52	GO:0071339	MLL1 complex
0.47	GO:0005829	cytosol
0.43	GO:0030529	intracellular ribonucleoprotein complex

0.81

EC:3.6.1

GO:0043141

sp|Q8AWY2|HXAAB_DANRE
Homeobox protein Hox-A10b
Search

0.92	homeobox protein Hox-A10

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0009954	proximal/distal pattern formation
0.49	GO:0030326	embryonic limb morphogenesis
0.48	GO:0009952	anterior/posterior pattern specification
0.47	GO:0021520	spinal cord motor neuron cell fate specification
0.47	GO:0001501	skeletal system development
0.46	GO:0050905	neuromuscular process
0.46	GO:0006366	transcription by RNA polymerase II

0.64	GO:0043565	sequence-specific DNA binding
0.47	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding
0.40	GO:0042826	histone deacetylase binding
0.39	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.39	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.43	GO:0150005	enzyme activator complex
0.43	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.41	GO:0043233	organelle lumen
0.39	GO:0036464	cytoplasmic ribonucleoprotein granule
0.38	GO:0005667	transcription factor complex
0.38	GO:0044446	intracellular organelle part
0.37	GO:0005829	cytosol

sp|Q8AWY9|HXB7A_DANRE
Homeobox protein Hox-B7a
Search

HOXB7

0.97	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

0.67	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
0.49	GO:0006366	transcription by RNA polymerase II
0.48	GO:1902680	positive regulation of RNA biosynthetic process
0.47	GO:0030154	cell differentiation
0.47	GO:0002376	immune system process
0.47	GO:0009653	anatomical structure morphogenesis

0.65	GO:0043565	sequence-specific DNA binding
0.59	GO:0003700	DNA binding transcription factor activity
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.32	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.46	GO:0005829	cytosol
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part

sp|Q8AWZ0|HXB8A_DANRE
Homeobox protein Hox-B8a
Search

0.88	Homeobox protein Hox-B8

0.69	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0007625	grooming behavior
0.52	GO:0009653	anatomical structure morphogenesis
0.51	GO:1902679	negative regulation of RNA biosynthetic process
0.51	GO:0019233	sensory perception of pain
0.51	GO:0045638	negative regulation of myeloid cell differentiation
0.50	GO:0008344	adult locomotory behavior

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.36	GO:0001012	RNA polymerase II regulatory region DNA binding
0.35	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.44	GO:0015630	microtubule cytoskeleton

sp|Q8AWZ2|HXA3A_DANRE
Homeobox protein Hox-A3a
Search

0.91	Transcription factor HoxB3

0.68	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:0001974	blood vessel remodeling
0.47	GO:0061448	connective tissue development
0.44	GO:0008284	positive regulation of cell proliferation
0.43	GO:0009653	anatomical structure morphogenesis
0.43	GO:0002376	immune system process
0.39	GO:0006351	transcription, DNA-templated

0.64	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.48	GO:0071837	HMG box domain binding
0.37	GO:0001012	RNA polymerase II regulatory region DNA binding
0.37	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.42	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part
0.39	GO:0016235	aggresome

tr|Q8AX86|Q8AX86_DANRE
Elongation of very long chain fatty acids protein 5
Search

ELOVL5

0.73	Elongation of very long chain fatty acids protein 5

0.85	GO:0019367	fatty acid elongation, saturated fatty acid
0.85	GO:0042761	very long-chain fatty acid biosynthetic process
0.83	GO:0034626	fatty acid elongation, polyunsaturated fatty acid
0.83	GO:0034625	fatty acid elongation, monounsaturated fatty acid
0.82	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.79	GO:0006636	unsaturated fatty acid biosynthetic process
0.54	GO:0045723	positive regulation of fatty acid biosynthetic process
0.45	GO:0042759	long-chain fatty acid biosynthetic process
0.45	GO:0030148	sphingolipid biosynthetic process
0.35	GO:0036109	alpha-linolenic acid metabolic process

0.85	GO:0009922	fatty acid elongase activity
0.82	GO:0102756	very-long-chain 3-ketoacyl-CoA synthase activity
0.82	GO:0102337	3-oxo-cerotoyl-CoA synthase activity
0.82	GO:0102338	3-oxo-lignoceronyl-CoA synthase activity
0.82	GO:0102336	3-oxo-arachidoyl-CoA synthase activity
0.33	GO:0016874	ligase activity
0.33	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.77	GO:0097447	dendritic tree
0.72	GO:0120038	plasma membrane bounded cell projection part
0.70	GO:0005783	endoplasmic reticulum
0.68	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.64	GO:0031984	organelle subcompartment
0.52	GO:0043025	neuronal cell body
0.35	GO:0005887	integral component of plasma membrane

0.82

EC:2.3.1.199

GO:0102337

tr|Q8AX99|Q8AX99_DANRE
Actinin alpha 3b
Search

ACTN3

0.94	Truncated alpha-actinin

0.58	GO:0006936	muscle contraction
0.56	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway
0.55	GO:0030035	microspike assembly
0.55	GO:0048041	focal adhesion assembly
0.55	GO:2001137	positive regulation of endocytic recycling
0.55	GO:0045214	sarcomere organization
0.55	GO:0048513	animal organ development
0.54	GO:2000009	negative regulation of protein localization to cell surface
0.54	GO:1901017	negative regulation of potassium ion transmembrane transporter activity
0.54	GO:1904025	positive regulation of glucose catabolic process to lactate via pyruvate

0.73	GO:0003779	actin binding
0.70	GO:0005509	calcium ion binding
0.56	GO:0070080	titin Z domain binding
0.55	GO:0030375	thyroid hormone receptor coactivator activity
0.55	GO:0051373	FATZ binding
0.54	GO:0031432	titin binding
0.54	GO:0032403	protein complex binding
0.53	GO:0030274	LIM domain binding
0.53	GO:0044325	ion channel binding
0.52	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding

0.59	GO:0030018	Z disc
0.52	GO:0030175	filopodium
0.52	GO:0005925	focal adhesion
0.50	GO:0005903	brush border
0.40	GO:0005886	plasma membrane
0.38	GO:0015629	actin cytoskeleton
0.38	GO:0070062	extracellular exosome
0.37	GO:0044430	cytoskeletal part
0.37	GO:0030863	cortical cytoskeleton
0.36	GO:0031143	pseudopodium

sp|Q8AXB3|VGFR4_DANRE
Vascular endothelial growth factor receptor kdr-like
Search

0.57	Vascular endothelial growth factor receptor 1

0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.69	GO:0035924	cellular response to vascular endothelial growth factor stimulus
0.50	GO:0001525	angiogenesis
0.47	GO:0030878	thyroid gland development
0.46	GO:0048844	artery morphogenesis
0.46	GO:0030154	cell differentiation
0.46	GO:0035050	embryonic heart tube development
0.41	GO:0046777	protein autophosphorylation
0.40	GO:0035474	selective angioblast sprouting

0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0019838	growth factor binding
0.40	GO:0046983	protein dimerization activity
0.39	GO:0042802	identical protein binding
0.36	GO:0050660	flavin adenine dinucleotide binding
0.34	GO:0016491	oxidoreductase activity

0.50	GO:0005887	integral component of plasma membrane
0.38	GO:0005634	nucleus
0.38	GO:0005769	early endosome
0.37	GO:0030054	cell junction
0.36	GO:0005783	endoplasmic reticulum

0.80

EC:2.7.10.1

GO:0004714

sp|Q8AXV5|HEYL_DANRE
Hairy/enhancer-of-split related with YRPW motif-like protein
Search

HEY1

0.91	Hairy/enhancer-of-split related with YRPW motif protein 1

0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.53	GO:0007219	Notch signaling pathway
0.52	GO:0051145	smooth muscle cell differentiation
0.52	GO:2000678	negative regulation of transcription regulatory region DNA binding
0.52	GO:0045746	negative regulation of Notch signaling pathway
0.50	GO:0048514	blood vessel morphogenesis
0.49	GO:0048646	anatomical structure formation involved in morphogenesis

0.67	GO:0046983	protein dimerization activity
0.55	GO:0035939	microsatellite binding
0.48	GO:0000989	transcription factor activity, transcription factor binding
0.43	GO:0003700	DNA binding transcription factor activity
0.38	GO:0042802	identical protein binding
0.36	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.35	GO:0050683	AF-1 domain binding
0.35	GO:0008134	transcription factor binding

0.60	GO:0005634	nucleus
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q8AXV6|HEY1_DANRE
Hairy/enhancer-of-split related with YRPW motif protein 1
Search

HEY1

0.96	Hairy/enhancer-of-split related with YRPW motif protein 1

0.58	GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2000678	negative regulation of transcription regulatory region DNA binding
0.55	GO:0045746	negative regulation of Notch signaling pathway
0.55	GO:0007219	Notch signaling pathway
0.53	GO:0048514	blood vessel morphogenesis
0.51	GO:0048646	anatomical structure formation involved in morphogenesis
0.40	GO:0060842	arterial endothelial cell differentiation
0.40	GO:0035907	dorsal aorta development
0.39	GO:0061027	umbilical cord development

0.68	GO:0046983	protein dimerization activity
0.58	GO:0035939	microsatellite binding
0.50	GO:0000989	transcription factor activity, transcription factor binding
0.44	GO:0003700	DNA binding transcription factor activity
0.37	GO:0042802	identical protein binding
0.35	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q8AXX2|TBX1_DANRE
T-box transcription factor TBX1
Search

TBX1

0.95	T-box transcription factor

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0060017	parathyroid gland development
0.50	GO:0060023	soft palate development
0.50	GO:0060037	pharyngeal system development
0.49	GO:0048538	thymus development
0.49	GO:0048703	embryonic viscerocranium morphogenesis
0.47	GO:0007507	heart development

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.45	GO:0042803	protein homodimerization activity
0.36	GO:0001067	regulatory region nucleic acid binding
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0016787	hydrolase activity
0.33	GO:0005525	GTP binding

0.61	GO:0005634	nucleus
0.34	GO:0008021	synaptic vesicle
0.30	GO:0016020	membrane

0.33

GO:0016620

tr|Q8AXX6|Q8AXX6_DANRE
Ppp2r5e2 protein
Search

PPP2R5E

0.61	Serine/threonine protein phosphatase 2A regulatory subunit

0.78	GO:0043666	regulation of phosphoprotein phosphatase activity
0.60	GO:0007165	signal transduction

0.79	GO:0019888	protein phosphatase regulator activity
0.34	GO:0005515	protein binding

0.80	GO:0000159	protein phosphatase type 2A complex
0.46	GO:0005829	cytosol

sp|Q8AXZ4|CNT1A_DANRE
Contactin-1a
Search

CNTN1

0.90	LOW QUALITY PROTEIN: contactin-1

0.76	GO:0031175	neuron projection development
0.51	GO:0010765	positive regulation of sodium ion transport
0.50	GO:0010975	regulation of neuron projection development
0.50	GO:0007420	brain development
0.48	GO:0031346	positive regulation of cell projection organization
0.48	GO:0045666	positive regulation of neuron differentiation
0.47	GO:0010628	positive regulation of gene expression
0.42	GO:0071206	establishment of protein localization to juxtaparanode region of axon
0.42	GO:0097090	presynaptic membrane organization
0.42	GO:0045163	clustering of voltage-gated potassium channels

0.46	GO:0030246	carbohydrate binding
0.40	GO:0043621	protein self-association
0.34	GO:0050839	cell adhesion molecule binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0043209	myelin sheath
0.41	GO:0044224	juxtaparanode region of axon
0.41	GO:0033268	node of Ranvier
0.40	GO:0043025	neuronal cell body
0.39	GO:0031225	anchored component of membrane
0.39	GO:0008076	voltage-gated potassium channel complex
0.39	GO:0009986	cell surface
0.38	GO:0045121	membrane raft
0.36	GO:0070062	extracellular exosome

tr|Q8AY15|Q8AY15_DANRE
Mothers against decapentaplegic homolog
Search

SMAD3

0.65	Mothers against decapentaplegic homolog

0.83	GO:0007179	transforming growth factor beta receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0006355	regulation of transcription, DNA-templated
0.55	GO:0033689	negative regulation of osteoblast proliferation
0.54	GO:0048617	embryonic foregut morphogenesis
0.54	GO:0007183	SMAD protein complex assembly
0.54	GO:0048340	paraxial mesoderm morphogenesis
0.54	GO:0051481	negative regulation of cytosolic calcium ion concentration
0.54	GO:0002076	osteoblast development
0.54	GO:0038092	nodal signaling pathway

0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0031962	mineralocorticoid receptor binding
0.55	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
0.55	GO:0003677	DNA binding
0.54	GO:0035259	glucocorticoid receptor binding
0.54	GO:0017151	DEAD/H-box RNA helicase binding
0.54	GO:0070410	co-SMAD binding
0.54	GO:0070878	primary miRNA binding
0.53	GO:0070412	R-SMAD binding
0.53	GO:0043425	bHLH transcription factor binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.54	GO:0071141	SMAD protein complex
0.49	GO:0043235	receptor complex
0.49	GO:0005737	cytoplasm
0.46	GO:0000785	chromatin
0.45	GO:0070013	intracellular organelle lumen
0.45	GO:0012505	endomembrane system
0.42	GO:0019866	organelle inner membrane
0.40	GO:0005886	plasma membrane

tr|Q8AY63|Q8AY63_DANRE
Brain-subtype creatine kinase
Search

0.93	Brain-subtype creatine kinase

0.57	GO:0016310	phosphorylation
0.49	GO:0046314	phosphocreatine biosynthetic process
0.45	GO:0009408	response to heat
0.43	GO:0030644	cellular chloride ion homeostasis
0.40	GO:0007420	brain development
0.37	GO:0048857	neural nucleus development
0.35	GO:0006600	creatine metabolic process
0.33	GO:0006754	ATP biosynthetic process

0.65	GO:0004111	creatine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0031625	ubiquitin protein ligase binding

0.51	GO:0005615	extracellular space
0.48	GO:0043209	myelin sheath
0.44	GO:0005829	cytosol
0.41	GO:0005739	mitochondrion
0.38	GO:0043025	neuronal cell body
0.38	GO:0030425	dendrite
0.37	GO:0043230	extracellular organelle
0.35	GO:0005634	nucleus
0.35	GO:0031982	vesicle

0.65	EC:2.7.3.2	GO:0004111
0.65	KEGG:R01881	GO:0004111

tr|Q8AY90|Q8AY90_DANRE
Fibroblast growth factor
Search

FGF10

0.62	Fibroblast growth factor

0.83	GO:0008543	fibroblast growth factor receptor signaling pathway
0.75	GO:0010469	regulation of receptor activity
0.60	GO:0048732	gland development
0.59	GO:0061033	secretion by lung epithelial cell involved in lung growth
0.59	GO:0051549	positive regulation of keratinocyte migration
0.58	GO:0010838	positive regulation of keratinocyte proliferation
0.58	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
0.57	GO:0050674	urothelial cell proliferation
0.57	GO:0050918	positive chemotaxis
0.57	GO:0009888	tissue development

0.85	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.58	GO:0042056	chemoattractant activity
0.51	GO:0008201	heparin binding
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0004713	protein tyrosine kinase activity
0.33	GO:0004335	galactokinase activity
0.33	GO:0005534	galactose binding

0.66	GO:0005576	extracellular region
0.49	GO:0009986	cell surface
0.43	GO:0005634	nucleus
0.41	GO:0005886	plasma membrane
0.40	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|Q8AYB8|HOP_DANRE
Homeodomain-only protein
Search

HOPX

0.75	HOP homeobox

0.55	GO:0007507	heart development
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0006351	transcription, DNA-templated
0.34	GO:0055085	transmembrane transport

0.54	GO:0003677	DNA binding
0.39	GO:0003700	DNA binding transcription factor activity
0.37	GO:0015267	channel activity

0.61	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q8AYE3|Q8AYE3_DANRE
Antithrombin
Search

SERPINC1

0.97	Serpin peptidase inhibitor clade C member 1

0.85	GO:2000266	regulation of blood coagulation, intrinsic pathway
0.72	GO:0010951	negative regulation of endopeptidase activity
0.48	GO:0071391	cellular response to estrogen stimulus
0.42	GO:0002438	acute inflammatory response to antigenic stimulus
0.41	GO:0007595	lactation
0.40	GO:0007584	response to nutrient
0.39	GO:0007596	blood coagulation
0.38	GO:0042129	regulation of T cell proliferation
0.37	GO:0002697	regulation of immune effector process
0.36	GO:0010608	posttranscriptional regulation of gene expression

0.76	GO:0008201	heparin binding
0.74	GO:0004867	serine-type endopeptidase inhibitor activity
0.56	GO:0002020	protease binding
0.50	GO:0042802	identical protein binding
0.38	GO:0003730	mRNA 3'-UTR binding
0.34	GO:0046872	metal ion binding
0.34	GO:0035613	RNA stem-loop binding
0.34	GO:0104005	hijacked molecular function
0.33	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.33	GO:0016874	ligase activity

0.73	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0035578	azurophil granule lumen
0.33	GO:0000932	P-body
0.33	GO:0010494	cytoplasmic stress granule
0.32	GO:0005886	plasma membrane
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.33

GO:0016874

sp|Q8AYG3|TTK_DANRE
Dual specificity protein kinase Ttk
Search

LOC106605052

0.63	Dual specificity protein kinase Ttk

0.80	GO:0007093	mitotic cell cycle checkpoint
0.79	GO:0051304	chromosome separation
0.63	GO:0006468	protein phosphorylation
0.37	GO:0140013	meiotic nuclear division
0.37	GO:1903096	protein localization to meiotic spindle midzone
0.36	GO:0044779	meiotic spindle checkpoint
0.36	GO:0034501	protein localization to kinetochore
0.36	GO:0018210	peptidyl-threonine modification
0.36	GO:0071173	spindle assembly checkpoint
0.35	GO:0018209	peptidyl-serine modification

0.82	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0004674	protein serine/threonine kinase activity
0.35	GO:0042803	protein homodimerization activity
0.30	GO:0004713	protein tyrosine kinase activity
0.30	GO:0043169	cation binding

0.35	GO:0000776	kinetochore
0.35	GO:0005680	anaphase-promoting complex
0.32	GO:0005737	cytoplasm

0.82

EC:2.7.12.1

GO:0004712

sp|Q8AYM7|OPSG3_DANRE
Green-sensitive opsin-3
Search

0.56	Green-sensitive opsin

0.79	GO:0007602	phototransduction
0.78	GO:0007601	visual perception
0.74	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.42	GO:0016038	absorption of visible light
0.40	GO:0009584	detection of visible light

0.79	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.40	GO:0001750	photoreceptor outer segment
0.30	GO:0044425	membrane part

sp|Q8AYM8|OPSG2_DANRE
Green-sensitive opsin-2
Search

0.55	Green-sensitive opsin

0.79	GO:0007602	phototransduction
0.78	GO:0007601	visual perception
0.75	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.56	GO:0016038	absorption of visible light
0.40	GO:0009584	detection of visible light

0.79	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.41	GO:0001750	photoreceptor outer segment
0.30	GO:0044425	membrane part

sp|Q8AYN0|OPSR2_DANRE
Red-sensitive opsin-2
Search

0.79	Long wavelength-sensitive cone opsin

0.79	GO:0007602	phototransduction
0.78	GO:0007601	visual perception
0.75	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.37	GO:0009584	detection of visible light
0.35	GO:0016039	absorption of UV light
0.35	GO:0016038	absorption of visible light
0.35	GO:0010017	red or far-red light signaling pathway
0.35	GO:0009648	photoperiodism

0.79	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.37	GO:0001750	photoreceptor outer segment
0.30	GO:0044425	membrane part

tr|Q8AYN1|Q8AYN1_DANRE
Pbx/knotted 1 homeobox 2
Search

PKNOX2

0.97	Pbx/knotted 1 homeobox 2

0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.44	GO:0030218	erythrocyte differentiation
0.44	GO:0030217	T cell differentiation
0.43	GO:0001525	angiogenesis
0.43	GO:0043010	camera-type eye development
0.42	GO:0006366	transcription by RNA polymerase II
0.41	GO:0051254	positive regulation of RNA metabolic process
0.41	GO:0010557	positive regulation of macromolecule biosynthetic process

0.56	GO:0003785	actin monomer binding
0.54	GO:0003677	DNA binding
0.52	GO:0051015	actin filament binding
0.51	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.43	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.41	GO:0046982	protein heterodimerization activity

0.60	GO:0005634	nucleus
0.56	GO:0045171	intercellular bridge
0.50	GO:0015629	actin cytoskeleton
0.49	GO:0015630	microtubule cytoskeleton
0.48	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.42	GO:0005667	transcription factor complex
0.40	GO:0005737	cytoplasm
0.34	GO:0045271	respiratory chain complex I
0.33	GO:1990204	oxidoreductase complex

sp|Q8JFB7|ORML1_DANRE
ORM1-like protein 1
Search

ORMDL1

0.97	ORMDL sphingolipid biosynthesis regulator 1

0.85	GO:0090155	negative regulation of sphingolipid biosynthetic process
0.82	GO:0006672	ceramide metabolic process
0.67	GO:0090156	cellular sphingolipid homeostasis
0.65	GO:2000303	regulation of ceramide biosynthetic process
0.57	GO:0034249	negative regulation of cellular amide metabolic process
0.34	GO:0043312	neutrophil degranulation

0.33

GO:0005515

protein binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.56	GO:0002178	palmitoyltransferase complex
0.35	GO:0035579	specific granule membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q8JFD2|Q8JFD2_DANRE
Gap junction protein
Search

GJA3

0.61	Gap junction protein alpha 3

0.72	GO:0007601	visual perception
0.60	GO:0007154	cell communication
0.52	GO:0055085	transmembrane transport
0.48	GO:0048050	post-embryonic eye morphogenesis
0.47	GO:0003161	cardiac conduction system development
0.46	GO:0055008	cardiac muscle tissue morphogenesis
0.45	GO:0008016	regulation of heart contraction
0.42	GO:0002088	lens development in camera-type eye
0.39	GO:0031444	slow-twitch skeletal muscle fiber contraction
0.35	GO:0042542	response to hydrogen peroxide

0.82	GO:0005243	gap junction channel activity
0.34	GO:0042802	identical protein binding

0.84	GO:0005922	connexin complex
0.34	GO:0045121	membrane raft
0.34	GO:0005887	integral component of plasma membrane

tr|Q8JFD6|Q8JFD6_DANRE
Gap junction protein
Search

GJD2

0.64	Gap junction delta-2 protein (Fragment)

0.60	GO:0007154	cell communication
0.54	GO:0001508	action potential
0.51	GO:0007601	visual perception
0.44	GO:0023052	signaling
0.40	GO:0007416	synapse assembly
0.34	GO:0034220	ion transmembrane transport

0.38	GO:0005243	gap junction channel activity
0.35	GO:0022832	voltage-gated channel activity
0.35	GO:0022839	ion gated channel activity
0.35	GO:0008381	mechanosensitive ion channel activity
0.33	GO:0005515	protein binding

0.84	GO:0005922	connexin complex
0.30	GO:0031224	intrinsic component of membrane

tr|Q8JFP9|Q8JFP9_DANRE
Gdf11-like
Search

GDF11

0.87	Growth differentiation factor 11

0.75	GO:0010469	regulation of receptor activity
0.59	GO:2000818	negative regulation of myoblast proliferation
0.59	GO:0045596	negative regulation of cell differentiation
0.59	GO:0014859	negative regulation of skeletal muscle cell proliferation
0.58	GO:0014842	regulation of skeletal muscle satellite cell proliferation
0.58	GO:0048642	negative regulation of skeletal muscle tissue development
0.58	GO:2001014	regulation of skeletal muscle cell differentiation
0.56	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.54	GO:0021512	spinal cord anterior/posterior patterning
0.51	GO:0033002	muscle cell proliferation

0.78	GO:0008083	growth factor activity
0.49	GO:0005125	cytokine activity
0.49	GO:0005160	transforming growth factor beta receptor binding
0.47	GO:0008201	heparin binding
0.44	GO:0042802	identical protein binding
0.41	GO:0046983	protein dimerization activity

0.66	GO:0005576	extracellular region
0.45	GO:0005654	nucleoplasm
0.41	GO:0043234	protein complex
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q8JFQ2|RBTN1_DANRE
Rhombotin-1
Search

LMO1

0.96	LIM domain only 1

0.54	GO:0046013	regulation of T cell homeostatic proliferation
0.48	GO:0000122	negative regulation of transcription by RNA polymerase II
0.47	GO:0045944	positive regulation of transcription by RNA polymerase II
0.43	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway
0.42	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway
0.41	GO:0045600	positive regulation of fat cell differentiation
0.41	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0006351	transcription, DNA-templated

0.54	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.42	GO:0005634	nucleus
0.35	GO:0043233	organelle lumen
0.34	GO:0005737	cytoplasm
0.34	GO:0044446	intracellular organelle part
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q8JFR5|KITA_DANRE
Mast/stem cell growth factor receptor kita
Search

KIT

0.65	KIT proto-oncogene receptor tyrosine kinase

0.86	GO:0038109	Kit signaling pathway
0.85	GO:0038093	Fc receptor signaling pathway
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.65	GO:0023014	signal transduction by protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.58	GO:0097324	melanocyte migration
0.57	GO:0097326	melanocyte adhesion
0.57	GO:0002371	dendritic cell cytokine production
0.57	GO:0060374	mast cell differentiation
0.57	GO:0030318	melanocyte differentiation

0.85	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity
0.83	GO:0019955	cytokine binding
0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.51	GO:0002020	protease binding
0.47	GO:0042803	protein homodimerization activity

0.54	GO:0042629	mast cell granule
0.50	GO:0009897	external side of plasma membrane
0.48	GO:0005911	cell-cell junction
0.47	GO:0005615	extracellular space
0.39	GO:0001669	acrosomal vesicle
0.38	GO:0009898	cytoplasmic side of plasma membrane
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.85	EC:2.7.10	GO:0004716
0.35	KEGG:R04545	GO:0046934

tr|Q8JFT6|Q8JFT6_DANRE
Novel protein
Search

SPRYD7

0.97	SPRY domain-containing protein 7

0.45

GO:0005515

protein binding

0.30

GO:0044425

membrane part

tr|Q8JFT7|Q8JFT7_DANRE
Importin subunit alpha
Search

KPNA3

0.61	Importin subunit alpha

0.79	GO:0006606	protein import into nucleus
0.44	GO:0042542	response to hydrogen peroxide
0.35	GO:0016125	sterol metabolic process
0.34	GO:1902594	multi-organism nuclear import
0.34	GO:0075733	intracellular transport of virus
0.33	GO:0044068	modulation by symbiont of host cellular process
0.33	GO:0006461	protein complex assembly
0.33	GO:0019048	modulation by virus of host morphology or physiology
0.33	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.33	GO:0044409	entry into host

0.82	GO:0061608	nuclear import signal receptor activity
0.65	GO:0008565	protein transporter activity
0.53	GO:0008022	protein C-terminus binding
0.48	GO:0008139	nuclear localization sequence binding
0.36	GO:0047750	cholestenol delta-isomerase activity

0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.45	GO:0012505	endomembrane system
0.42	GO:0031967	organelle envelope
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0043234	protein complex
0.38	GO:0031090	organelle membrane
0.34	GO:0070062	extracellular exosome
0.33	GO:0044217	other organism part
0.33	GO:0018995	host

0.36

EC:5.3.3.5

GO:0047750

tr|Q8JFU2|Q8JFU2_DANRE
Novel ubiquitin
Search

TMUB2

0.94	Transmembrane and ubiquitin like domain containing 2

0.43

GO:0030433

ubiquitin-dependent ERAD pathway

0.34

GO:0005515

protein binding

0.41	GO:0005654	nucleoplasm
0.40	GO:0005829	cytosol
0.36	GO:0055037	recycling endosome
0.35	GO:0045211	postsynaptic membrane
0.35	GO:0005815	microtubule organizing center
0.35	GO:0030054	cell junction
0.35	GO:0005730	nucleolus
0.30	GO:0016021	integral component of membrane

sp|Q8JFV4|HTR5A_DANRE
HEAT repeat-containing protein 5A
Search

HEATR5A

0.56	HEAT repeat-containing protein 5A

0.49	GO:0043043	peptide biosynthetic process
0.46	GO:0044267	cellular protein metabolic process
0.45	GO:0010467	gene expression
0.44	GO:0009059	macromolecule biosynthetic process

0.52

GO:0003735

structural constituent of ribosome

0.60	GO:0070062	extracellular exosome
0.50	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

tr|Q8JFV5|Q8JFV5_DANRE
HECT domain-containing 1
Search

HECTD1

0.53	HECT domain-containing 1

0.72	GO:0016567	protein ubiquitination
0.38	GO:0060708	spongiotrophoblast differentiation
0.38	GO:0001779	natural killer cell differentiation
0.38	GO:0060707	trophoblast giant cell differentiation
0.38	GO:1903077	negative regulation of protein localization to plasma membrane
0.37	GO:0003170	heart valve development
0.37	GO:0035904	aorta development
0.37	GO:0003281	ventricular septum development
0.37	GO:0001843	neural tube closure

0.73	GO:0004842	ubiquitin-protein transferase activity
0.53	GO:0046872	metal ion binding
0.51	GO:0016874	ligase activity
0.47	GO:0061659	ubiquitin-like protein ligase activity
0.34	GO:0005515	protein binding

0.37

GO:0005737

cytoplasm

0.51	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

sp|Q8JFV8|VAT1_DANRE
Synaptic vesicle membrane protein VAT-1 homolog
Search

VAT1

0.93	Synaptic vesicle membrane protein VAT-1

0.60	GO:0010637	negative regulation of mitochondrial fusion
0.52	GO:0055114	oxidation-reduction process
0.35	GO:0043312	neutrophil degranulation
0.33	GO:1903506	regulation of nucleic acid-templated transcription

0.57	GO:0008270	zinc ion binding
0.53	GO:0016491	oxidoreductase activity
0.35	GO:0003712	transcription cofactor activity
0.34	GO:0008134	transcription factor binding
0.33	GO:0003723	RNA binding
0.31	GO:0048037	cofactor binding

0.39	GO:0005741	mitochondrial outer membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:0099503	secretory vesicle
0.35	GO:0044433	cytoplasmic vesicle part
0.35	GO:0005766	primary lysosome
0.35	GO:0031983	vesicle lumen
0.35	GO:0005775	vacuolar lumen
0.35	GO:0012505	endomembrane system
0.34	GO:0098793	presynapse
0.34	GO:0012506	vesicle membrane

0.53

GO:0016491

sp|Q8JFW1|ASND1_DANRE
Asparagine synthetase domain-containing protein 1
Search

ASNSD1

0.87	Asparagine synthetase domain-containing protein 1

0.77	GO:0006529	asparagine biosynthetic process
0.39	GO:0006541	glutamine metabolic process

0.77	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity
0.45	GO:0042803	protein homodimerization activity

0.77

EC:6.3.5.4

GO:0004066

sp|Q8JFW4|ADAT3_DANRE
Probable inactive tRNA-specific adenosine deaminase-like protein 3
Search

ADAT3

0.96	Adenosine deaminase, tRNA-specific 3

0.45	GO:0009451	RNA modification
0.42	GO:0008033	tRNA processing
0.35	GO:0015031	protein transport
0.33	GO:0036297	interstrand cross-link repair
0.33	GO:0006464	cellular protein modification process
0.33	GO:0006364	rRNA processing
0.33	GO:0051604	protein maturation
0.32	GO:0016310	phosphorylation

0.49	GO:0019239	deaminase activity
0.41	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
0.37	GO:0046872	metal ion binding
0.34	GO:0009982	pseudouridine synthase activity
0.33	GO:0016874	ligase activity
0.33	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.32	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.41	EC:3.5.4	GO:0016814
0.33	KEGG:R03876	GO:0004842

tr|Q8JFW7|Q8JFW7_DANRE
B-cell receptor-associated protein 31
Search

BCAP31

0.91	B-cell receptor-associated protein 31

0.69	GO:0006886	intracellular protein transport
0.59	GO:0070973	protein localization to endoplasmic reticulum exit site
0.54	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol
0.54	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process
0.53	GO:0006888	ER to Golgi vesicle-mediated transport
0.52	GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration
0.52	GO:0051561	positive regulation of mitochondrial calcium ion concentration
0.52	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.51	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.50	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

0.53	GO:0042288	MHC class I protein binding
0.47	GO:0032403	protein complex binding
0.35	GO:0044325	ion channel binding
0.33	GO:0008271	secondary active sulfate transmembrane transporter activity
0.33	GO:0042393	histone binding
0.33	GO:0003682	chromatin binding

0.70	GO:0005783	endoplasmic reticulum
0.49	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.49	GO:0005811	lipid droplet
0.48	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0031984	organelle subcompartment
0.46	GO:0044431	Golgi apparatus part
0.46	GO:0098588	bounding membrane of organelle
0.44	GO:0005887	integral component of plasma membrane
0.42	GO:0098796	membrane protein complex
0.41	GO:0005739	mitochondrion

sp|Q8JG38|FGFR2_DANRE
Fibroblast growth factor receptor 2
Search

FGFR2

0.77	Fibroblast growth factor receptor

0.82	GO:0008543	fibroblast growth factor receptor signaling pathway
0.77	GO:0008284	positive regulation of cell proliferation
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.48	GO:0010518	positive regulation of phospholipase activity
0.47	GO:0048701	embryonic cranial skeleton morphogenesis
0.46	GO:0046777	protein autophosphorylation
0.46	GO:0043410	positive regulation of MAPK cascade
0.38	GO:0030901	midbrain development
0.38	GO:0061351	neural precursor cell proliferation
0.37	GO:0048565	digestive tract development

0.85	GO:0005007	fibroblast growth factor-activated receptor activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0017134	fibroblast growth factor binding
0.44	GO:0042803	protein homodimerization activity
0.35	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0004908	interleukin-1 receptor activity
0.35	GO:0016303	1-phosphatidylinositol-3-kinase activity

0.44	GO:0005938	cell cortex
0.44	GO:0009986	cell surface
0.44	GO:0031012	extracellular matrix
0.43	GO:0005654	nucleoplasm
0.41	GO:0005887	integral component of plasma membrane
0.36	GO:0060076	excitatory synapse
0.36	GO:0031410	cytoplasmic vesicle
0.36	GO:0005794	Golgi apparatus

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

tr|Q8JG61|Q8JG61_DANRE
Erythrocyte membrane protein band 4.1 (Elliptocytosis 1, RH-linked)
Search

0.73	GO:0030866	cortical actin cytoskeleton organization
0.61	GO:0007016	cytoskeletal anchoring at plasma membrane
0.58	GO:0001558	regulation of cell growth
0.50	GO:1904778	positive regulation of protein localization to cell cortex
0.47	GO:0032092	positive regulation of protein binding
0.42	GO:0008360	regulation of cell shape
0.42	GO:0031032	actomyosin structure organization
0.38	GO:0006461	protein complex assembly
0.37	GO:0035023	regulation of Rho protein signal transduction
0.37	GO:0006897	endocytosis

0.70	GO:0008092	cytoskeletal protein binding
0.58	GO:0005198	structural molecule activity
0.46	GO:0047485	protein N-terminus binding
0.46	GO:0051219	phosphoprotein binding
0.46	GO:0005545	1-phosphatidylinositol binding
0.46	GO:0008022	protein C-terminus binding
0.37	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.36	GO:0005516	calmodulin binding
0.35	GO:0005509	calcium ion binding
0.34	GO:0050811	GABA receptor binding

0.68	GO:0005856	cytoskeleton
0.58	GO:0030054	cell junction
0.47	GO:0005886	plasma membrane
0.47	GO:0099738	cell cortex region
0.42	GO:0014069	postsynaptic density
0.40	GO:0005829	cytosol
0.39	GO:0098562	cytoplasmic side of membrane
0.39	GO:0043234	protein complex
0.35	GO:0044224	juxtaparanode region of axon
0.35	GO:0033270	paranode region of axon

sp|Q8JG69|AA2DB_DANRE
Alpha-2Db adrenergic receptor
Search

0.82	Alpha-2 adrenergic receptor

0.84	GO:0071875	adrenergic receptor signaling pathway
0.78	GO:0006940	regulation of smooth muscle contraction
0.77	GO:0019229	regulation of vasoconstriction
0.77	GO:0030168	platelet activation
0.46	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.44	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.43	GO:0007267	cell-cell signaling
0.40	GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
0.40	GO:0051930	regulation of sensory perception of pain
0.40	GO:0045932	negative regulation of muscle contraction

0.84	GO:0004935	adrenergic receptor activity
0.40	GO:0031694	alpha-2A adrenergic receptor binding
0.40	GO:0051379	epinephrine binding
0.38	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity

0.54	GO:0005886	plasma membrane
0.39	GO:0043679	axon terminus
0.38	GO:0030424	axon
0.35	GO:0005622	intracellular
0.34	GO:0031982	vesicle
0.34	GO:0012505	endomembrane system
0.33	GO:0031975	envelope
0.33	GO:0044422	organelle part
0.30	GO:0016021	integral component of membrane

sp|Q8JG70|AA2DA_DANRE
Alpha-2Da adrenergic receptor
Search

0.69	Adrenergic, alpha-2D-, receptor a

0.83	GO:0071875	adrenergic receptor signaling pathway
0.74	GO:0006940	regulation of smooth muscle contraction
0.74	GO:0019229	regulation of vasoconstriction
0.74	GO:0030168	platelet activation
0.42	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.40	GO:0007267	cell-cell signaling
0.37	GO:0051930	regulation of sensory perception of pain
0.37	GO:0045932	negative regulation of muscle contraction
0.37	GO:1903524	positive regulation of blood circulation
0.37	GO:0007565	female pregnancy

0.83

GO:0004935

adrenergic receptor activity

0.54	GO:0005886	plasma membrane
0.37	GO:0043679	axon terminus
0.36	GO:0030424	axon
0.34	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

tr|Q8JGR2|Q8JGR2_DANRE
ATP-dependent RNA helicase
Search

DDX54

0.97	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54

0.56	GO:1903507	negative regulation of nucleic acid-templated transcription
0.52	GO:0010501	RNA secondary structure unwinding
0.51	GO:0006396	RNA processing

0.78	GO:0004004	ATP-dependent RNA helicase activity
0.66	GO:0030331	estrogen receptor binding
0.62	GO:0003714	transcription corepressor activity
0.59	GO:0003723	RNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.56	GO:0005794	Golgi apparatus
0.55	GO:0031974	membrane-enclosed lumen
0.49	GO:0043232	intracellular non-membrane-bounded organelle
0.48	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q8JGR4|RL24_DANRE
60S ribosomal protein L24
Search

RPL24

0.74	Ribosomal protein L24

0.50	GO:1902626	assembly of large subunit precursor of preribosome
0.49	GO:0000027	ribosomal large subunit assembly
0.47	GO:0002181	cytoplasmic translation
0.45	GO:0021554	optic nerve development
0.45	GO:0010458	exit from mitosis
0.45	GO:0031290	retinal ganglion cell axon guidance
0.44	GO:0060041	retina development in camera-type eye
0.43	GO:0007093	mitotic cell cycle checkpoint
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.35	GO:0043009	chordate embryonic development

0.49	GO:0045296	cadherin binding
0.42	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.59	GO:0005840	ribosome
0.48	GO:0044445	cytosolic part
0.48	GO:0005844	polysome
0.45	GO:0005783	endoplasmic reticulum
0.42	GO:0044446	intracellular organelle part
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

sp|Q8JGR6|NCBP2_DANRE
Nuclear cap-binding protein subunit 2
Search

NCBP2

0.70	Nuclear cap-binding protein subunit 2

0.83	GO:0045292	mRNA cis splicing, via spliceosome
0.50	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.49	GO:0031442	positive regulation of mRNA 3'-end processing
0.48	GO:0098789	pre-mRNA cleavage required for polyadenylation
0.46	GO:0006408	snRNA export from nucleus
0.46	GO:0006446	regulation of translational initiation
0.45	GO:0046833	positive regulation of RNA export from nucleus
0.43	GO:0031047	gene silencing by RNA
0.42	GO:0051028	mRNA transport
0.37	GO:1900363	regulation of mRNA polyadenylation

0.83	GO:0000339	RNA cap binding
0.50	GO:0017069	snRNA binding
0.47	GO:0003729	mRNA binding
0.33	GO:0005515	protein binding

0.84	GO:0005846	nuclear cap binding complex
0.61	GO:0005634	nucleus
0.48	GO:0005845	mRNA cap binding complex
0.43	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part
0.37	GO:0005737	cytoplasm

sp|Q8JGR7|INT7_DANRE
Integrator complex subunit 7
Search

INTS7

0.95	LOW QUALITY PROTEIN: integrator complex subunit 7

0.81	GO:0016180	snRNA processing
0.57	GO:0071479	cellular response to ionizing radiation
0.55	GO:0000077	DNA damage checkpoint
0.47	GO:0002088	lens development in camera-type eye
0.45	GO:0043628	ncRNA 3'-end processing
0.35	GO:0042795	snRNA transcription by RNA polymerase II
0.34	GO:0006367	transcription initiation from RNA polymerase II promoter

0.33

GO:0005515

protein binding

0.81	GO:0032039	integrator complex
0.53	GO:0016604	nuclear body
0.49	GO:0005694	chromosome
0.39	GO:0005737	cytoplasm
0.34	GO:0005672	transcription factor TFIIA complex

tr|Q8JGR8|Q8JGR8_DANRE
Lysosome membrane protein II
Search

0.66	Lysosome membrane protein II

0.46	GO:1905123	regulation of glucosylceramidase activity
0.46	GO:0006622	protein targeting to lysosome
0.44	GO:0001508	action potential
0.40	GO:0048731	system development
0.39	GO:0031346	positive regulation of cell projection organization
0.39	GO:0010720	positive regulation of cell development
0.39	GO:0051962	positive regulation of nervous system development
0.39	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.38	GO:0030154	cell differentiation
0.37	GO:0009790	embryo development

0.65	GO:0004872	receptor activity
0.41	GO:0019899	enzyme binding
0.36	GO:0104005	hijacked molecular function

0.79	GO:0005764	lysosome
0.44	GO:0005775	vacuolar lumen
0.42	GO:0098852	lytic vacuole membrane
0.38	GO:0005925	focal adhesion
0.38	GO:0070062	extracellular exosome
0.36	GO:0031902	late endosome membrane
0.36	GO:0030665	clathrin-coated vesicle membrane
0.35	GO:0009986	cell surface
0.35	GO:0000139	Golgi membrane
0.35	GO:0005789	endoplasmic reticulum membrane

sp|Q8JGS0|RU1C_DANRE
U1 small nuclear ribonucleoprotein C
Search

SNRPC

0.74	Small nuclear ribonucleoprotein polypeptide C variant (Fragment)

0.80	GO:0000387	spliceosomal snRNP assembly
0.79	GO:0000395	mRNA 5'-splice site recognition
0.42	GO:0000381	regulation of alternative mRNA splicing, via spliceosome

0.76	GO:0030619	U1 snRNA binding
0.68	GO:0003729	mRNA binding
0.62	GO:0008270	zinc ion binding
0.51	GO:0030627	pre-mRNA 5'-splice site binding
0.50	GO:0003727	single-stranded RNA binding
0.48	GO:0042803	protein homodimerization activity
0.39	GO:1990446	U1 snRNP binding
0.32	GO:0003677	DNA binding

0.81	GO:0005685	U1 snRNP
0.77	GO:0000243	commitment complex
0.76	GO:0071010	prespliceosome
0.56	GO:0019013	viral nucleocapsid
0.53	GO:0015030	Cajal body

sp|Q8JGS1|STIL_DANRE
SCL-interrupting locus protein homolog
Search

STIL

0.85	STIL, centriolar assembly protein

0.84	GO:0046599	regulation of centriole replication
0.82	GO:0007052	mitotic spindle organization
0.81	GO:0071539	protein localization to centrosome
0.78	GO:0051298	centrosome duplication
0.56	GO:0007224	smoothened signaling pathway
0.55	GO:0070050	neuron cellular homeostasis
0.53	GO:0010171	body morphogenesis
0.52	GO:0051225	spindle assembly
0.48	GO:0007275	multicellular organism development
0.44	GO:0035264	multicellular organism growth

0.44	GO:0005515	protein binding
0.34	GO:0004435	phosphatidylinositol phospholipase C activity
0.34	GO:0098772	molecular function regulator
0.33	GO:0008201	heparin binding
0.32	GO:0003723	RNA binding

0.81	GO:0005814	centriole
0.73	GO:0005813	centrosome
0.41	GO:0005829	cytosol
0.33	GO:0005615	extracellular space

0.34	EC:3.1.4.11	GO:0004435
0.34	KEGG:R03435	GO:0004435

sp|Q8JGS9|RS18_DANRE
40S ribosomal protein S18
Search

RPS18

0.44	Ribosomal protein S18

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.43	GO:0042254	ribosome biogenesis
0.41	GO:0051726	regulation of cell cycle
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0060079	excitatory postsynaptic potential
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0035235	ionotropic glutamate receptor signaling pathway

0.64	GO:0003735	structural constituent of ribosome
0.59	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.34	GO:0005234	extracellularly glutamate-gated ion channel activity
0.34	GO:0008378	galactosyltransferase activity
0.34	GO:0004970	ionotropic glutamate receptor activity
0.33	GO:0046873	metal ion transmembrane transporter activity
0.32	GO:0016491	oxidoreductase activity

0.61	GO:0005840	ribosome
0.45	GO:0005829	cytosol
0.41	GO:0044446	intracellular organelle part
0.37	GO:0005634	nucleus
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0098794	postsynapse

0.34

GO:0008378

sp|Q8JGW0|TSP4B_DANRE
Thrombospondin-4-B
Search

THBS4

0.96	Thrombospondin-4-B

0.81	GO:0030198	extracellular matrix organization
0.72	GO:0007155	cell adhesion
0.58	GO:0051451	myoblast migration
0.58	GO:0048266	behavioral response to pain
0.57	GO:0090023	positive regulation of neutrophil chemotaxis
0.56	GO:0034103	regulation of tissue remodeling
0.56	GO:0001938	positive regulation of endothelial cell proliferation
0.55	GO:0016525	negative regulation of angiogenesis
0.55	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.53	GO:0034976	response to endoplasmic reticulum stress

0.70	GO:0005509	calcium ion binding
0.56	GO:0008201	heparin binding
0.55	GO:0005178	integrin binding
0.40	GO:0008083	growth factor activity
0.39	GO:0005518	collagen binding
0.39	GO:0043395	heparan sulfate proteoglycan binding
0.39	GO:0002020	protease binding
0.36	GO:0043237	laminin-1 binding
0.35	GO:0001968	fibronectin binding
0.32	GO:0005201	extracellular matrix structural constituent

0.74	GO:0031012	extracellular matrix
0.56	GO:0016529	sarcoplasmic reticulum
0.51	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:0031594	neuromuscular junction

tr|Q8JH29|Q8JH29_DANRE
Angiotensinogen
Search

AGT

0.87	Liver angiotensinogen

0.85	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin
0.42	GO:0010951	negative regulation of endopeptidase activity
0.32	GO:0006508	proteolysis

0.42	GO:0004867	serine-type endopeptidase inhibitor activity
0.32	GO:0008233	peptidase activity

0.73	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0008233

sp|Q8JH47|CDK8_DANRE
Cyclin-dependent kinase 8
Search

CDK8

0.96	Cell division protein kinase 8

0.60	GO:0006468	protein phosphorylation
0.44	GO:0007346	regulation of mitotic cell cycle
0.38	GO:0051301	cell division
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.34	GO:0000082	G1/S transition of mitotic cell cycle
0.34	GO:1902680	positive regulation of RNA biosynthetic process

0.60	GO:0004672	protein kinase activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0060089	molecular transducer activity
0.34	GO:0005515	protein binding

0.53	GO:0016592	mediator complex
0.49	GO:0005730	nucleolus

sp|Q8JH55|HXB8B_DANRE
Homeobox protein Hox-B8b
Search

0.87	Homeobox protein Hox-B8

0.68	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0007625	grooming behavior
0.52	GO:0019233	sensory perception of pain
0.52	GO:0045638	negative regulation of myeloid cell differentiation
0.51	GO:0008344	adult locomotory behavior
0.50	GO:0009653	anatomical structure morphogenesis
0.50	GO:1902679	negative regulation of RNA biosynthetic process

0.63	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.43	GO:0001012	RNA polymerase II regulatory region DNA binding
0.41	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.45	GO:0031974	membrane-enclosed lumen
0.41	GO:0044446	intracellular organelle part

sp|Q8JH68|MXA_DANRE
Interferon-induced GTP-binding protein MxA
Search

0.74	Interferon-induced GTP-binding protein MxA

0.44	GO:0006952	defense response
0.44	GO:0002376	immune system process
0.43	GO:0009615	response to virus
0.43	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission
0.42	GO:0000266	mitochondrial fission
0.42	GO:0034097	response to cytokine
0.39	GO:0045071	negative regulation of viral genome replication
0.38	GO:0061025	membrane fusion
0.36	GO:0046822	regulation of nucleocytoplasmic transport
0.35	GO:0046685	response to arsenic-containing substance

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0008017	microtubule binding
0.36	GO:0042802	identical protein binding

0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005635	nuclear envelope
0.38	GO:0031090	organelle membrane
0.37	GO:0005829	cytosol
0.37	GO:0005740	mitochondrial envelope
0.36	GO:0005615	extracellular space
0.35	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q8JH70|ALDCB_DANRE
Fructose-bisphosphate aldolase C-B
Search

ALDOC

0.55	Fructose-bisphosphate aldolase C-B

0.70	GO:0006096	glycolytic process
0.54	GO:0030388	fructose 1,6-bisphosphate metabolic process
0.50	GO:0060429	epithelium development
0.48	GO:0030154	cell differentiation
0.43	GO:0006000	fructose metabolic process
0.42	GO:0046716	muscle cell cellular homeostasis
0.42	GO:0007339	binding of sperm to zona pellucida
0.42	GO:0001966	thigmotaxis
0.42	GO:0006941	striated muscle contraction
0.40	GO:0043473	pigmentation

0.78	GO:0004332	fructose-bisphosphate aldolase activity
0.48	GO:0008092	cytoskeletal protein binding
0.44	GO:0070061	fructose binding
0.41	GO:0045296	cadherin binding
0.36	GO:0002020	protease binding
0.36	GO:0042802	identical protein binding
0.35	GO:0061609	fructose-1-phosphate aldolase activity
0.34	GO:0051117	ATPase binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0003723	RNA binding

0.43	GO:0061827	sperm head
0.42	GO:0005739	mitochondrion
0.42	GO:0070062	extracellular exosome
0.40	GO:0015629	actin cytoskeleton
0.39	GO:0005829	cytosol
0.37	GO:0031430	M band
0.37	GO:0031674	I band
0.37	GO:0035686	sperm fibrous sheath
0.36	GO:0043209	myelin sheath
0.35	GO:1904724	tertiary granule lumen

0.78

EC:4.1.2.13

GO:0004332

sp|Q8JH71|ALDOB_DANRE
Fructose-bisphosphate aldolase B
Search

0.55	Fructose-bisphosphate aldolase B

0.71	GO:0006096	glycolytic process
0.55	GO:0030388	fructose 1,6-bisphosphate metabolic process
0.51	GO:0030855	epithelial cell differentiation
0.40	GO:0006000	fructose metabolic process
0.40	GO:0006734	NADH metabolic process
0.38	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly
0.38	GO:0001966	thigmotaxis
0.38	GO:0032781	positive regulation of ATPase activity
0.37	GO:0001756	somitogenesis
0.37	GO:0043473	pigmentation

0.79	GO:0004332	fructose-bisphosphate aldolase activity
0.49	GO:0008092	cytoskeletal protein binding
0.41	GO:0070061	fructose binding
0.40	GO:0061609	fructose-1-phosphate aldolase activity
0.39	GO:0051117	ATPase binding
0.37	GO:0042802	identical protein binding
0.35	GO:0045296	cadherin binding
0.34	GO:0004707	MAP kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0005739	mitochondrion
0.39	GO:0005856	cytoskeleton
0.37	GO:0070062	extracellular exosome
0.36	GO:0061827	sperm head
0.36	GO:0044446	intracellular organelle part
0.35	GO:0005829	cytosol
0.35	GO:0101002	ficolin-1-rich granule
0.35	GO:0070820	tertiary granule
0.35	GO:0031983	vesicle lumen
0.34	GO:0030424	axon

0.79	EC:4.1.2.13	GO:0004332
0.34	KEGG:R00162	GO:0004707

tr|Q8JHE0|Q8JHE0_DANRE
Casein kinase 1, alpha 1
Search

CSNK1A1

0.74	Casein kinase I alpha LS

0.63	GO:0006468	protein phosphorylation
0.55	GO:0018209	peptidyl-serine modification
0.52	GO:1904424	regulation of GTP binding
0.52	GO:0045104	intermediate filament cytoskeleton organization
0.51	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.50	GO:0007030	Golgi organization
0.46	GO:0048856	anatomical structure development
0.45	GO:0006909	phagocytosis
0.44	GO:0016055	Wnt signaling pathway
0.44	GO:0048869	cellular developmental process

0.66	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.34	GO:0042277	peptide binding
0.33	GO:0000287	magnesium ion binding

0.52	GO:0030877	beta-catenin destruction complex
0.51	GO:0045095	keratin filament
0.51	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex
0.50	GO:0016607	nuclear speck
0.49	GO:0036064	ciliary basal body
0.48	GO:0005813	centrosome
0.45	GO:0005829	cytosol
0.40	GO:0030529	intracellular ribonucleoprotein complex
0.39	GO:0000777	condensed chromosome kinetochore
0.37	GO:0005730	nucleolus

0.66

GO:0004674

sp|Q8JHE9|APH1B_DANRE
Gamma-secretase subunit Aph-1b
Search

APH1A

0.97	Anterior pharynx defective 1 homolog A

0.75	GO:0016485	protein processing
0.73	GO:0043085	positive regulation of catalytic activity
0.56	GO:0007220	Notch receptor processing
0.51	GO:0034205	amyloid-beta formation
0.50	GO:0031293	membrane protein intracellular domain proteolysis
0.49	GO:0006509	membrane protein ectodomain proteolysis
0.48	GO:0001656	metanephros development
0.48	GO:0007219	Notch signaling pathway
0.36	GO:0048013	ephrin receptor signaling pathway
0.36	GO:0008593	regulation of Notch signaling pathway

0.46	GO:0008233	peptidase activity
0.34	GO:0005515	protein binding

0.56	GO:0070765	gamma-secretase complex
0.49	GO:0012505	endomembrane system
0.46	GO:0005887	integral component of plasma membrane
0.45	GO:0031410	cytoplasmic vesicle
0.41	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0031984	organelle subcompartment

0.46

GO:0008233

sp|Q8JHF0|PEN2_DANRE
Gamma-secretase subunit PEN-2
Search

PSENEN

0.96	Presenilin enhancer gamma secretase subunit

0.64	GO:0007220	Notch receptor processing
0.58	GO:0034205	amyloid-beta formation
0.55	GO:0006509	membrane protein ectodomain proteolysis
0.51	GO:0097324	melanocyte migration
0.50	GO:0016485	protein processing
0.49	GO:0043085	positive regulation of catalytic activity
0.49	GO:0048066	developmental pigmentation
0.48	GO:0043524	negative regulation of neuron apoptotic process
0.42	GO:0007219	Notch signaling pathway
0.36	GO:0031293	membrane protein intracellular domain proteolysis

0.35	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.61	GO:0070765	gamma-secretase complex
0.49	GO:0005794	Golgi apparatus
0.48	GO:0005783	endoplasmic reticulum
0.46	GO:0005887	integral component of plasma membrane
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0098588	bounding membrane of organelle
0.39	GO:0031984	organelle subcompartment
0.37	GO:0017053	transcriptional repressor complex

sp|Q8JHF2|LFNG_DANRE
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
Search

LFNG

0.84	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

0.69	GO:0007389	pattern specification process
0.56	GO:0036066	protein O-linked fucosylation
0.54	GO:1902367	negative regulation of Notch signaling pathway involved in somitogenesis
0.53	GO:0002315	marginal zone B cell differentiation
0.52	GO:0009790	embryo development
0.51	GO:0045747	positive regulation of Notch signaling pathway
0.51	GO:0032092	positive regulation of protein binding
0.51	GO:0009888	tissue development
0.51	GO:0051446	positive regulation of meiotic cell cycle
0.50	GO:0001541	ovarian follicle development

0.79	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity
0.46	GO:0046872	metal ion binding
0.32	GO:0016491	oxidoreductase activity

0.70	GO:0030173	integral component of Golgi membrane
0.36	GO:1903561	extracellular vesicle

0.79

EC:2.4.1.222

GO:0033829

sp|Q8JHF4|MPP5A_DANRE
MAGUK p55 subfamily member 5-A
Search

MPP5

0.90	Membrane palmitoylated protein 5

0.83	GO:0070830	bicellular tight junction assembly
0.83	GO:0090162	establishment of epithelial cell polarity
0.60	GO:0035750	protein localization to myelin sheath abaxonal region
0.57	GO:0032287	peripheral nervous system myelin maintenance
0.56	GO:0002011	morphogenesis of an epithelial sheet
0.40	GO:0032288	myelin assembly
0.38	GO:0072659	protein localization to plasma membrane
0.36	GO:0021744	dorsal motor nucleus of vagus nerve development
0.36	GO:0016332	establishment or maintenance of polarity of embryonic epithelium
0.36	GO:0045199	maintenance of epithelial cell apical/basal polarity

0.52	GO:0019904	protein domain specific binding
0.34	GO:0004385	guanylate kinase activity

0.59	GO:0043219	lateral loop
0.58	GO:0035749	myelin sheath adaxonal region
0.58	GO:0043220	Schmidt-Lanterman incisure
0.55	GO:0005913	cell-cell adherens junction
0.44	GO:0043234	protein complex
0.42	GO:0005886	plasma membrane
0.39	GO:0005737	cytoplasm
0.39	GO:0005923	bicellular tight junction
0.36	GO:0070062	extracellular exosome
0.35	GO:0001917	photoreceptor inner segment

0.34

EC:2.7.4.8

GO:0004385

tr|Q8JHG4|Q8JHG4_DANRE
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor
Search

TAF7

0.89	Transcription initiation factor tfIId subunit 7

0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.58	GO:0006413	translational initiation
0.50	GO:0035067	negative regulation of histone acetylation
0.48	GO:0006357	regulation of transcription by RNA polymerase II
0.48	GO:0030520	intracellular estrogen receptor signaling pathway
0.48	GO:0006469	negative regulation of protein kinase activity
0.47	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.45	GO:0045893	positive regulation of transcription, DNA-templated
0.45	GO:0045892	negative regulation of transcription, DNA-templated
0.37	GO:0000296	spermine transport

0.59	GO:0003743	translation initiation factor activity
0.56	GO:0035035	histone acetyltransferase binding
0.53	GO:0061628	H3K27me3 modified histone binding
0.52	GO:0003713	transcription coactivator activity
0.52	GO:0042809	vitamin D receptor binding
0.51	GO:0046966	thyroid hormone receptor binding
0.50	GO:0044212	transcription regulatory region DNA binding
0.45	GO:0046982	protein heterodimerization activity
0.41	GO:0003700	DNA binding transcription factor activity

0.80	GO:0005669	transcription factor TFIID complex
0.50	GO:0033276	transcription factor TFTC complex
0.50	GO:0008024	cyclin/CDK positive transcription elongation factor complex
0.49	GO:0071339	MLL1 complex
0.44	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

tr|Q8JHH1|Q8JHH1_DANRE
Small nuclear ribonucleoprotein D1
Search

SNRPD1

0.84	Small nuclear ribonucleoprotein D1 polypeptide

0.81	GO:0000387	spliceosomal snRNP assembly
0.46	GO:0000245	spliceosomal complex assembly
0.43	GO:0007507	heart development
0.35	GO:1901800	positive regulation of proteasomal protein catabolic process
0.34	GO:0030163	protein catabolic process
0.34	GO:0001756	somitogenesis
0.34	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.34	GO:0001841	neural tube formation
0.34	GO:0045807	positive regulation of endocytosis
0.34	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

0.40	GO:0003723	RNA binding
0.38	GO:1990446	U1 snRNP binding
0.35	GO:0036402	proteasome-activating ATPase activity
0.33	GO:0003839	gamma-glutamylcyclotransferase activity
0.33	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008270	zinc ion binding

0.60	GO:0019013	viral nucleocapsid
0.60	GO:0030529	intracellular ribonucleoprotein complex
0.54	GO:0034715	pICln-Sm protein complex
0.54	GO:0034719	SMN-Sm protein complex
0.51	GO:0034709	methylosome
0.46	GO:0044428	nuclear part
0.44	GO:0005829	cytosol
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0005813	centrosome
0.33	GO:0031410	cytoplasmic vesicle

0.33	EC:2.3.2.4	GO:0003839
0.33	KEGG:R03876	GO:0004842

sp|Q8JHH5|CA109_DANRE
Uncharacterized protein C1orf109 homolog
Search

0.45

GO:0007275

multicellular organism development

0.38

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm

tr|Q8JHI0|Q8JHI0_DANRE
Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
Search

0.80	Adenine nucleotide translocase

0.55	GO:0055085	transmembrane transport
0.55	GO:0046902	regulation of mitochondrial membrane permeability
0.51	GO:0010823	negative regulation of mitochondrion organization
0.49	GO:2001234	negative regulation of apoptotic signaling pathway
0.49	GO:0015866	ADP transport
0.48	GO:0051051	negative regulation of transport
0.48	GO:0008284	positive regulation of cell proliferation
0.48	GO:0015867	ATP transport
0.46	GO:1990823	response to leukemia inhibitory factor
0.45	GO:0071345	cellular response to cytokine stimulus

0.57	GO:0022857	transmembrane transporter activity
0.47	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0003723	RNA binding

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.52	GO:0071817	MMXD complex
0.48	GO:0042645	mitochondrial nucleoid
0.48	GO:0043209	myelin sheath
0.38	GO:0045121	membrane raft
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.34	GO:0005887	integral component of plasma membrane
0.34	GO:0031301	integral component of organelle membrane

sp|Q8JHI3|AR13B_DANRE
ADP-ribosylation factor-like protein 13B
Search

ARL13B

0.94	ADP ribosylation factor like GTPase 13B

0.56	GO:0021943	formation of radial glial scaffolds
0.55	GO:0021830	interneuron migration from the subpallium to the cortex
0.54	GO:0060271	cilium assembly
0.54	GO:0070986	left/right axis specification
0.53	GO:0021532	neural tube patterning
0.52	GO:0001947	heart looping
0.52	GO:0007224	smoothened signaling pathway
0.51	GO:0009953	dorsal/ventral pattern formation
0.47	GO:0035845	photoreceptor cell outer segment organization
0.39	GO:0010226	response to lithium ion

0.64	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.52	GO:0032555	purine ribonucleotide binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0030742	GTP-dependent protein binding
0.33	GO:0008168	methyltransferase activity
0.33	GO:0003723	RNA binding
0.32	GO:0003735	structural constituent of ribosome

0.54	GO:0005929	cilium
0.51	GO:0031253	cell projection membrane
0.50	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.47	GO:0098588	bounding membrane of organelle
0.46	GO:0044430	cytoskeletal part
0.32	GO:0005840	ribosome

0.33

GO:0008168

sp|Q8JHI6|MED29_DANRE
Mediator of RNA polymerase II transcription subunit 29
Search

MED29

0.96	Mediator of RNA polymerase II transcription subunit 29

0.50	GO:0042462	eye photoreceptor cell development
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression

0.33

GO:0005515

protein binding

0.77

GO:0016592

mediator complex

sp|Q8JHJ1|RL35_DANRE
60S ribosomal protein L35
Search

RPL35

0.78	Ribosomal protein L35

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.47	GO:0042273	ribosomal large subunit biogenesis
0.44	GO:0016072	rRNA metabolic process
0.41	GO:0030218	erythrocyte differentiation
0.40	GO:0043009	chordate embryonic development
0.39	GO:0051726	regulation of cell cycle
0.35	GO:0071493	cellular response to UV-B

0.63	GO:0003735	structural constituent of ribosome
0.47	GO:0003729	mRNA binding
0.34	GO:0043021	ribonucleoprotein complex binding
0.33	GO:0044212	transcription regulatory region DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005840	ribosome
0.46	GO:0044445	cytosolic part
0.40	GO:0044446	intracellular organelle part
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0005634	nucleus
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q8JHJ2|DDX55_DANRE
ATP-dependent RNA helicase DDX55
Search

DDX55

0.52	RNA helicase

0.49	GO:0010501	RNA secondary structure unwinding
0.34	GO:0007275	multicellular organism development

0.65	GO:0004386	helicase activity
0.57	GO:0003723	RNA binding
0.53	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0008186	RNA-dependent ATPase activity
0.41	GO:0140098	catalytic activity, acting on RNA
0.33	GO:0005515	protein binding

0.52	GO:0005730	nucleolus
0.47	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q8JHV6|LAMB4_DANRE
Laminin subunit beta-4
Search

0.57	laminin subunit beta-4

0.66	GO:0030198	extracellular matrix organization
0.63	GO:0060429	epithelium development
0.63	GO:0016203	muscle attachment
0.59	GO:0048677	axon extension involved in regeneration
0.57	GO:0072224	metanephric glomerulus development
0.57	GO:0072202	cell differentiation involved in metanephros development
0.56	GO:0009790	embryo development
0.56	GO:0014002	astrocyte development
0.56	GO:0061318	renal filtration cell differentiation
0.55	GO:0014044	Schwann cell development

0.54

GO:0005178

integrin binding

0.63	GO:0005604	basement membrane
0.56	GO:0043083	synaptic cleft
0.49	GO:0005615	extracellular space
0.43	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q8JHW2|TSP3A_DANRE
Thrombospondin-3a
Search

THBS3

0.93	Thrombospondin 3

0.81	GO:0030198	extracellular matrix organization
0.72	GO:0007155	cell adhesion
0.55	GO:0060346	bone trabecula formation
0.55	GO:0003417	growth plate cartilage development
0.54	GO:0043931	ossification involved in bone maturation
0.43	GO:0051451	myoblast migration
0.43	GO:0048266	behavioral response to pain
0.43	GO:0090023	positive regulation of neutrophil chemotaxis
0.42	GO:0034103	regulation of tissue remodeling
0.42	GO:0001938	positive regulation of endothelial cell proliferation

0.80	GO:0008201	heparin binding
0.70	GO:0005509	calcium ion binding
0.42	GO:0005178	integrin binding
0.34	GO:0043395	heparan sulfate proteoglycan binding
0.34	GO:0002020	protease binding
0.34	GO:0005518	collagen binding

0.74	GO:0031012	extracellular matrix
0.51	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0016529	sarcoplasmic reticulum
0.40	GO:0005615	extracellular space
0.30	GO:0016020	membrane

tr|Q8JHX6|Q8JHX6_DANRE
Insulin-like growth factor binding protein 1a
Search

0.97	Insulin like growth factor binding protein 1

0.78	GO:0001558	regulation of cell growth
0.53	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.50	GO:0044342	type B pancreatic cell proliferation
0.47	GO:0010906	regulation of glucose metabolic process
0.46	GO:0031099	regeneration
0.46	GO:0043410	positive regulation of MAPK cascade
0.45	GO:0001666	response to hypoxia
0.44	GO:0008285	negative regulation of cell proliferation
0.36	GO:0006954	inflammatory response
0.35	GO:0008286	insulin receptor signaling pathway

0.84	GO:0005520	insulin-like growth factor binding
0.33	GO:0008160	protein tyrosine phosphatase activator activity
0.33	GO:0001968	fibronectin binding
0.33	GO:0005102	receptor binding

0.66	GO:0005576	extracellular region
0.39	GO:0005794	Golgi apparatus
0.34	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0036454	growth factor complex
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q8JI10|DMX1A_DANRE
Diencephalon/mesencephalon homeobox protein 1-A
Search

DMBX1

0.96	LOW QUALITY PROTEIN: diencephalon/mesencephalon homeobox protein 1

0.68	GO:0007275	multicellular organism development
0.58	GO:0060322	head development
0.56	GO:0061074	regulation of neural retina development
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.52	GO:0008343	adult feeding behavior
0.51	GO:1902679	negative regulation of RNA biosynthetic process
0.51	GO:0051960	regulation of nervous system development
0.50	GO:0060284	regulation of cell development

0.63	GO:0043565	sequence-specific DNA binding
0.50	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0042803	protein homodimerization activity
0.47	GO:0046982	protein heterodimerization activity
0.46	GO:0003690	double-stranded DNA binding

0.60	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

tr|Q8JI13|Q8JI13_DANRE
Homeobox protein Hox11
Search

0.96	T-cell leukemia homeobox protein 1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0002087	regulation of respiratory gaseous exchange by neurological system process
0.48	GO:0007585	respiratory gaseous exchange
0.48	GO:0048665	neuron fate specification
0.47	GO:0006366	transcription by RNA polymerase II
0.47	GO:0001764	neuron migration
0.47	GO:0045665	negative regulation of neuron differentiation
0.46	GO:1902680	positive regulation of RNA biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.50	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003690	double-stranded DNA binding
0.35	GO:0005515	protein binding
0.33	GO:0005198	structural molecule activity

0.61	GO:0005634	nucleus
0.42	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part
0.34	GO:0045111	intermediate filament cytoskeleton
0.33	GO:0099512	supramolecular fiber

sp|Q8JI14|RHCL2_DANRE
Ammonium transporter Rh type C-like 2
Search

0.87	Rhesus blood group-associated glycoprotein C

0.77	GO:0072488	ammonium transmembrane transport
0.57	GO:0070634	transepithelial ammonium transport
0.49	GO:0006885	regulation of pH
0.48	GO:0006873	cellular ion homeostasis
0.46	GO:0015695	organic cation transport
0.37	GO:0097272	ammonia homeostasis
0.36	GO:0006814	sodium ion transport
0.34	GO:0015837	amine transport
0.34	GO:0030855	epithelial cell differentiation

0.77	GO:0008519	ammonium transmembrane transporter activity
0.55	GO:0030506	ankyrin binding
0.47	GO:0042802	identical protein binding

0.54	GO:0016324	apical plasma membrane
0.52	GO:0016323	basolateral plasma membrane
0.47	GO:0005887	integral component of plasma membrane
0.39	GO:0031410	cytoplasmic vesicle
0.36	GO:0016327	apicolateral plasma membrane
0.34	GO:0070062	extracellular exosome
0.34	GO:0012506	vesicle membrane
0.32	GO:0044446	intracellular organelle part

tr|Q8JIE4|Q8JIE4_DANRE
Insulin-like growth factor 2
Search

0.95	Preproinsulin-growth factor II

0.76	GO:0010469	regulation of receptor activity
0.46	GO:0030903	notochord development
0.45	GO:0001756	somitogenesis
0.44	GO:0031101	fin regeneration
0.44	GO:0046628	positive regulation of insulin receptor signaling pathway
0.44	GO:0048793	pronephros development
0.43	GO:0042104	positive regulation of activated T cell proliferation
0.43	GO:0051897	positive regulation of protein kinase B signaling
0.42	GO:0045840	positive regulation of mitotic nuclear division
0.42	GO:0030900	forebrain development

0.79	GO:0005179	hormone activity
0.78	GO:0008083	growth factor activity
0.51	GO:0005159	insulin-like growth factor receptor binding
0.43	GO:0005158	insulin receptor binding
0.35	GO:0043539	protein serine/threonine kinase activator activity
0.34	GO:0004511	tyrosine 3-monooxygenase activity
0.32	GO:0005506	iron ion binding

0.73	GO:0005615	extracellular space
0.34	GO:1903561	extracellular vesicle
0.33	GO:0031093	platelet alpha granule lumen
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

EC:1.14.16.2

GO:0004511

tr|Q8JIG3|Q8JIG3_DANRE
BHLH-PAS transcription factor
Search

0.89	Neuronal PAS domain-containing protein 2

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0045739	positive regulation of DNA repair
0.47	GO:0051775	response to redox state
0.46	GO:0060548	negative regulation of cell death
0.44	GO:0051254	positive regulation of RNA metabolic process
0.44	GO:0010557	positive regulation of macromolecule biosynthetic process
0.44	GO:0031328	positive regulation of cellular biosynthetic process

0.68	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.52	GO:0003677	DNA binding
0.49	GO:0051879	Hsp90 protein binding
0.36	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0046872	metal ion binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.43	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part

sp|Q8JIR0|BMI1A_DANRE
Polycomb complex protein BMI-1-A
Search

BMI1

0.95	Polycomb group RING finger protein 4

0.81	GO:0033092	positive regulation of immature T cell proliferation in thymus
0.81	GO:0016574	histone ubiquitination
0.81	GO:2000011	regulation of adaxial/abaxial pattern formation
0.80	GO:0048704	embryonic skeletal system morphogenesis
0.79	GO:2001234	negative regulation of apoptotic signaling pathway
0.78	GO:0009952	anterior/posterior pattern specification
0.77	GO:0030890	positive regulation of B cell proliferation
0.76	GO:0048103	somatic stem cell division
0.76	GO:0021532	neural tube patterning
0.75	GO:0000122	negative regulation of transcription by RNA polymerase II

0.80	GO:1990841	promoter-specific chromatin binding
0.73	GO:0097027	ubiquitin-protein transferase activator activity
0.71	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0071535	RING-like zinc finger domain binding
0.42	GO:0008270	zinc ion binding
0.34	GO:0003700	DNA binding transcription factor activity

0.82	GO:0031519	PcG protein complex
0.79	GO:0000792	heterochromatin
0.76	GO:0016604	nuclear body
0.74	GO:0000151	ubiquitin ligase complex
0.57	GO:0000803	sex chromosome
0.51	GO:0000790	nuclear chromatin
0.38	GO:0005829	cytosol

sp|Q8JIS6|TBX6_DANRE
T-box transcription factor TBX6
Search

0.65	T-box transcription factor TBX6

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0014043	negative regulation of neuron maturation
0.52	GO:0001756	somitogenesis
0.50	GO:0001707	mesoderm formation
0.50	GO:0001708	cell fate specification
0.49	GO:0000578	embryonic axis specification
0.49	GO:0010977	negative regulation of neuron projection development

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.50	GO:0001102	RNA polymerase II activating transcription factor binding
0.50	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0019899	enzyme binding
0.35	GO:0046983	protein dimerization activity
0.34	GO:0005249	voltage-gated potassium channel activity
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0016787	hydrolase activity

0.61	GO:0005634	nucleus
0.38	GO:0000785	chromatin
0.37	GO:0034708	methyltransferase complex
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0017053	transcriptional repressor complex
0.33	GO:0005667	transcription factor complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33

GO:0016620

sp|Q8JIU7|NACA_DANRE
Nascent polypeptide-associated complex subunit alpha
Search

NACA

0.80	Nascent polypeptide-associated complex alpha polypeptide

0.45	GO:0030239	myofibril assembly
0.41	GO:1901227	negative regulation of transcription from RNA polymerase II promoter involved in heart development
0.40	GO:0048633	positive regulation of skeletal muscle tissue growth
0.39	GO:1901228	positive regulation of transcription from RNA polymerase II promoter involved in heart development
0.39	GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis
0.39	GO:0015031	protein transport
0.39	GO:0048742	regulation of skeletal muscle fiber development
0.39	GO:0010664	negative regulation of striated muscle cell apoptotic process
0.39	GO:0043403	skeletal muscle tissue regeneration
0.39	GO:0061384	heart trabecula morphogenesis

0.37	GO:0003713	transcription coactivator activity
0.36	GO:0017025	TBP-class protein binding
0.35	GO:0003677	DNA binding

0.84	GO:0005854	nascent polypeptide-associated complex
0.40	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome

sp|Q8JIY8|MK67I_DANRE
MKI67 FHA domain-interacting nucleolar phosphoprotein
Search

NIFK

0.88	Nucleolar protein interacting with the FHA domain of MKI67

0.36	GO:0007275	multicellular organism development
0.35	GO:0009303	rRNA transcription
0.34	GO:0006461	protein complex assembly

0.58	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.45	GO:0005730	nucleolus
0.44	GO:0000794	condensed nuclear chromosome
0.42	GO:0005654	nucleoplasm
0.36	GO:0005737	cytoplasm

tr|Q8JIZ3|Q8JIZ3_DANRE
Cone rod homeobox
Search

OTX2

0.79	Orthodenticle homeobox 2

0.70	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1902680	positive regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0006366	transcription by RNA polymerase II
0.54	GO:0009653	anatomical structure morphogenesis
0.53	GO:0060322	head development
0.45	GO:0120036	plasma membrane bounded cell projection organization
0.45	GO:0048468	cell development

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.57	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.48	GO:0030426	growth cone
0.40	GO:0043234	protein complex

sp|Q8JJ26|SEBOX_DANRE
Homeobox protein SEBOX
Search

0.86	Homeobox protein SEBOX

0.57	GO:0007492	endoderm development
0.56	GO:2000382	positive regulation of mesoderm development
0.56	GO:1901533	negative regulation of hematopoietic progenitor cell differentiation
0.54	GO:0007507	heart development
0.54	GO:0042074	cell migration involved in gastrulation
0.53	GO:0002244	hematopoietic progenitor cell differentiation
0.52	GO:0001704	formation of primary germ layer
0.52	GO:0048565	digestive tract development
0.49	GO:0006366	transcription by RNA polymerase II
0.49	GO:0045944	positive regulation of transcription by RNA polymerase II

0.55	GO:0003677	DNA binding
0.55	GO:0001103	RNA polymerase II repressing transcription factor binding
0.54	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.53	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.52	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.49	GO:0001067	regulatory region nucleic acid binding
0.49	GO:0042803	protein homodimerization activity
0.33	GO:0004672	protein kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding

0.61	GO:0005634	nucleus
0.47	GO:0000785	chromatin
0.45	GO:0043233	organelle lumen

tr|Q8JJ62|Q8JJ62_DANRE
Tmem165 protein
Search

TMEM165

0.51	Transmembrane protein 165

0.58	GO:0032472	Golgi calcium ion transport
0.56	GO:0035751	regulation of lysosomal lumen pH
0.55	GO:0006487	protein N-linked glycosylation
0.52	GO:0006874	cellular calcium ion homeostasis
0.46	GO:0060536	cartilage morphogenesis
0.45	GO:0048703	embryonic viscerocranium morphogenesis
0.45	GO:0002062	chondrocyte differentiation
0.44	GO:0001649	osteoblast differentiation
0.33	GO:0006629	lipid metabolic process
0.32	GO:0055114	oxidation-reduction process

0.33

GO:0016627

oxidoreductase activity, acting on the CH-CH group of donors

0.54	GO:0032588	trans-Golgi network membrane
0.52	GO:0005765	lysosomal membrane
0.51	GO:0010008	endosome membrane
0.37	GO:0005770	late endosome
0.37	GO:0005769	early endosome
0.30	GO:0016021	integral component of membrane

0.33

EC:1.3

GO:0016627

tr|Q8QFM3|Q8QFM3_DANRE
Frizzled 7a
Search

FZD7

0.93	Frizzled class receptor 7

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.57	GO:0035412	regulation of catenin import into nucleus
0.57	GO:0060429	epithelium development
0.55	GO:0045995	regulation of embryonic development
0.54	GO:0009653	anatomical structure morphogenesis
0.53	GO:2000384	negative regulation of ectoderm development
0.53	GO:0010562	positive regulation of phosphorus metabolic process
0.52	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
0.52	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing

0.85	GO:0042813	Wnt-activated receptor activity
0.59	GO:0017147	Wnt-protein binding
0.57	GO:0030165	PDZ domain binding
0.57	GO:0005109	frizzled binding
0.49	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.47	GO:0004930	G-protein coupled receptor activity
0.38	GO:0045545	syndecan binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0004672	protein kinase activity

0.50	GO:0055038	recycling endosome membrane
0.44	GO:0009986	cell surface
0.42	GO:0005886	plasma membrane
0.35	GO:0005925	focal adhesion
0.35	GO:1990909	Wnt signalosome
0.34	GO:0043005	neuron projection
0.30	GO:0016021	integral component of membrane

tr|Q8QFX4|Q8QFX4_DANRE
Helix-loop-helix protein
Search

ID3

0.92	Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.54	GO:0048699	generation of neurons
0.53	GO:0061031	endodermal digestive tract morphogenesis
0.53	GO:0045578	negative regulation of B cell differentiation
0.53	GO:0003166	bundle of His development
0.53	GO:0043433	negative regulation of DNA binding transcription factor activity
0.52	GO:0045668	negative regulation of osteoblast differentiation
0.52	GO:0045777	positive regulation of blood pressure
0.52	GO:0001966	thigmotaxis
0.52	GO:0048557	embryonic digestive tract morphogenesis

0.68	GO:0046983	protein dimerization activity
0.51	GO:0044325	ion channel binding
0.47	GO:0003677	DNA binding
0.40	GO:1901707	leptomycin B binding
0.38	GO:0008134	transcription factor binding
0.37	GO:0019904	protein domain specific binding
0.36	GO:0003700	DNA binding transcription factor activity
0.34	GO:0008113	peptide-methionine (S)-S-oxide reductase activity

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.41	GO:0043234	protein complex
0.33	GO:0000785	chromatin

0.34

EC:1.8.4 EC:1.8.4.11

GO:0008113

sp|Q8QFX6|NRP1A_DANRE
Neuropilin-1a
Search

NRP1

0.92	Neuropilin

0.86	GO:0035767	endothelial cell chemotaxis
0.85	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.85	GO:0038084	vascular endothelial growth factor signaling pathway
0.83	GO:0071526	semaphorin-plexin signaling pathway
0.82	GO:0001525	angiogenesis
0.81	GO:0007411	axon guidance
0.77	GO:0009887	animal organ morphogenesis
0.61	GO:0038189	neuropilin signaling pathway
0.60	GO:0006930	substrate-dependent cell migration, cell extension
0.60	GO:1905040	otic placode development

0.85	GO:0005021	vascular endothelial growth factor-activated receptor activity
0.84	GO:0017154	semaphorin receptor activity
0.82	GO:0019838	growth factor binding
0.53	GO:0046872	metal ion binding
0.52	GO:0005096	GTPase activator activity
0.52	GO:0019901	protein kinase binding
0.41	GO:0008201	heparin binding
0.35	GO:0015026	coreceptor activity
0.35	GO:0019955	cytokine binding

0.58	GO:0097443	sorting endosome
0.56	GO:0005883	neurofilament
0.55	GO:0005925	focal adhesion
0.53	GO:0005769	early endosome
0.53	GO:0030424	axon
0.49	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane
0.39	GO:0030426	growth cone
0.38	GO:0043025	neuronal cell body
0.37	GO:0009986	cell surface

tr|Q8QG63|Q8QG63_DANRE
LIM domain only 4
Search

LMO4

0.96	LIM domain transcription factor LMO4-B

0.55	GO:0021527	spinal cord association neuron differentiation
0.54	GO:0021514	ventral spinal cord interneuron differentiation
0.54	GO:0042659	regulation of cell fate specification
0.54	GO:0021522	spinal cord motor neuron differentiation
0.53	GO:0048538	thymus development
0.53	GO:0003281	ventricular septum development
0.53	GO:0001843	neural tube closure
0.51	GO:0031333	negative regulation of protein complex assembly
0.50	GO:0030334	regulation of cell migration
0.50	GO:0033674	positive regulation of kinase activity

0.54	GO:0046872	metal ion binding
0.53	GO:0001158	enhancer sequence-specific DNA binding
0.48	GO:0008134	transcription factor binding
0.37	GO:0003712	transcription cofactor activity
0.33	GO:0003700	DNA binding transcription factor activity

0.51	GO:0031252	cell leading edge
0.48	GO:0005667	transcription factor complex

tr|Q8QGA2|Q8QGA2_DANRE
Parathyroid hormone 2
Search

PTH2

0.95	Tuberoinfundibular peptide of 39 residues

0.80	GO:0007218	neuropeptide signaling pathway
0.51	GO:0006171	cAMP biosynthetic process
0.49	GO:0010469	regulation of receptor activity

0.49

GO:0048018

receptor ligand activity

0.66	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|Q8QGE3|Q8QGE3_DANRE
Activin beta A subunit
Search

0.84	Activin beta A subunit

0.76	GO:0010469	regulation of receptor activity
0.48	GO:0031101	fin regeneration
0.47	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.46	GO:0046880	regulation of follicle-stimulating hormone secretion
0.46	GO:0060279	positive regulation of ovulation
0.46	GO:0042701	progesterone secretion
0.46	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.45	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.45	GO:0042541	hemoglobin biosynthetic process
0.45	GO:0021773	striatal medium spiny neuron differentiation

0.78	GO:0008083	growth factor activity
0.64	GO:0005179	hormone activity
0.46	GO:0005125	cytokine activity
0.45	GO:0070699	type II activin receptor binding
0.44	GO:0017046	peptide hormone binding
0.42	GO:0005160	transforming growth factor beta receptor binding
0.41	GO:0042802	identical protein binding
0.35	GO:0034711	inhibin binding
0.35	GO:0046983	protein dimerization activity

0.66	GO:0005576	extracellular region
0.43	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0043234	protein complex

tr|Q8QGU1|Q8QGU1_DANRE
Gastrulation brain homeo box 2
Search

GBX2

0.96	Gastrulation brain homeo box 2

0.59	GO:0021568	rhombomere 2 development
0.58	GO:0021555	midbrain-hindbrain boundary morphogenesis
0.58	GO:0021549	cerebellum development
0.57	GO:0021930	cerebellar granule cell precursor proliferation
0.57	GO:0021953	central nervous system neuron differentiation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0021794	thalamus development
0.56	GO:0010468	regulation of gene expression
0.56	GO:0007411	axon guidance

0.64	GO:0043565	sequence-specific DNA binding
0.54	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.53	GO:0001047	core promoter binding
0.52	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|Q8QGU7|Q8QGU7_DANRE
Olfactory marker protein
Search

OMP

0.97	Olfactory marker protein b

0.76	GO:0007608	sensory perception of smell
0.61	GO:0007165	signal transduction
0.44	GO:0098916	anterograde trans-synaptic signaling
0.42	GO:0022008	neurogenesis
0.37	GO:0006508	proteolysis

0.64	GO:0004871	signal transducer activity
0.42	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.35	GO:0042277	peptide binding
0.34	GO:0005515	protein binding

0.47	GO:0043025	neuronal cell body
0.46	GO:0030424	axon
0.43	GO:0005829	cytosol
0.40	GO:0005634	nucleus

tr|Q8QGV5|Q8QGV5_DANRE
Lipocalin-type prostaglandin D synthase-like protein
Search

0.50	Prostaglandine D synthase

0.38

GO:0010951

negative regulation of endopeptidase activity

0.51	GO:0036094	small molecule binding
0.44	GO:0004667	prostaglandin-D synthase activity
0.42	GO:0005501	retinoid binding
0.38	GO:0004866	endopeptidase inhibitor activity
0.35	GO:0043168	anion binding

0.30

GO:0031224

intrinsic component of membrane

0.44	EC:5.3.99.2	GO:0004667
0.44	KEGG:R02266	GO:0004667

tr|Q8QGW4|Q8QGW4_DANRE
Rapsyn protein
Search

RAPSN

0.97	Receptor-associated protein of the synapse

0.75	GO:0007268	chemical synaptic transmission
0.60	GO:0043525	positive regulation of neuron apoptotic process
0.43	GO:1900075	positive regulation of neuromuscular synaptic transmission
0.42	GO:0050808	synapse organization
0.42	GO:1901626	regulation of postsynaptic membrane organization
0.41	GO:0043113	receptor clustering
0.37	GO:0061024	membrane organization
0.37	GO:0007399	nervous system development
0.35	GO:0022607	cellular component assembly

0.85	GO:0033130	acetylcholine receptor binding
0.85	GO:0043495	protein membrane anchor
0.42	GO:0035255	ionotropic glutamate receptor binding
0.35	GO:0046872	metal ion binding

0.73	GO:0045202	synapse
0.55	GO:0005813	centrosome
0.55	GO:0098590	plasma membrane region
0.51	GO:0005794	Golgi apparatus
0.50	GO:0005829	cytosol
0.39	GO:0030054	cell junction

tr|Q8QHA3|Q8QHA3_DANRE
Claudin
Search

CLDN10

0.67

Claudin

0.52	GO:0043269	regulation of ion transport
0.38	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.35	GO:0006811	ion transport
0.34	GO:0048546	digestive tract morphogenesis
0.34	GO:0035148	tube formation

0.62	GO:0005198	structural molecule activity
0.35	GO:0042802	identical protein binding

0.81	GO:0005923	bicellular tight junction
0.55	GO:0005886	plasma membrane
0.39	GO:0005737	cytoplasm
0.33	GO:0012505	endomembrane system
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0044425	membrane part

tr|Q8QHA4|Q8QHA4_DANRE
Family with sequence similarity 101, member A
Search

0.97

Refilin A

0.86	GO:0061181	regulation of chondrocyte development
0.83	GO:0061572	actin filament bundle organization
0.57	GO:1900158	negative regulation of bone mineralization involved in bone maturation
0.55	GO:0032331	negative regulation of chondrocyte differentiation
0.52	GO:0048705	skeletal system morphogenesis
0.52	GO:0010721	negative regulation of cell development
0.41	GO:0001837	epithelial to mesenchymal transition

0.86

GO:0031005

filamin binding

0.53	GO:0032432	actin filament bundle
0.33	GO:0005737	cytoplasm

tr|Q8QHI1|Q8QHI1_DANRE
Sodium/potassium-transporting ATPase subunit beta
Search

0.79	Sodium/potassium-transporting ATPase subunit beta

0.72	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.54	GO:1903288	positive regulation of potassium ion import
0.54	GO:1903278	positive regulation of sodium ion export across plasma membrane
0.53	GO:0006883	cellular sodium ion homeostasis
0.52	GO:0086009	membrane repolarization
0.52	GO:1901018	positive regulation of potassium ion transmembrane transporter activity
0.51	GO:0030007	cellular potassium ion homeostasis
0.51	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.50	GO:0140115	export across plasma membrane

0.51	GO:0051117	ATPase binding
0.51	GO:0005391	sodium:potassium-exchanging ATPase activity
0.49	GO:0001671	ATPase activator activity

0.84	GO:0005890	sodium:potassium-exchanging ATPase complex
0.40	GO:0042470	melanosome
0.38	GO:0098590	plasma membrane region
0.37	GO:0045121	membrane raft
0.36	GO:0070062	extracellular exosome
0.35	GO:0045177	apical part of cell

0.51

GO:0005391

sp|Q8QHJ8|XPO6_DANRE
Exportin-6
Search

XPO6

0.94	Exportin-6-B

0.66	GO:0006886	intracellular protein transport
0.56	GO:0006611	protein export from nucleus
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.76	GO:0008536	Ran GTPase binding
0.49	GO:0008565	protein transporter activity
0.32	GO:0044212	transcription regulatory region DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.60	GO:0005634	nucleus
0.48	GO:0005829	cytosol
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0043232	intracellular non-membrane-bounded organelle
0.43	GO:0044446	intracellular organelle part
0.42	GO:0005886	plasma membrane

sp|Q8QHJ9|I17RD_DANRE
Interleukin-17 receptor D
Search

IL17RD

0.97	Interleukin-17 receptor D

0.61	GO:0019221	cytokine-mediated signaling pathway
0.45	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway
0.44	GO:0000188	inactivation of MAPK activity
0.43	GO:0009953	dorsal/ventral pattern formation
0.39	GO:0000165	MAPK cascade

0.69	GO:0030368	interleukin-17 receptor activity
0.35	GO:0003676	nucleic acid binding

0.67	GO:0005794	Golgi apparatus
0.66	GO:0005654	nucleoplasm
0.53	GO:0005887	integral component of plasma membrane
0.40	GO:0098588	bounding membrane of organelle
0.39	GO:0031984	organelle subcompartment

sp|Q8QHL5|PHC2_DANRE
Polyhomeotic-like protein 2
Search

PHC2

0.87	Polyhomeotic homolog 2

0.57

GO:0007283

spermatogenesis

0.63	GO:0008270	zinc ion binding
0.54	GO:0042802	identical protein binding

0.63	GO:0035102	PRC1 complex
0.58	GO:0000792	heterochromatin
0.52	GO:0005654	nucleoplasm

sp|Q8UUR3|CYGB1_DANRE
Cytoglobin-1
Search

CYGB

0.94	cytoglobin

0.79	GO:0015671	oxygen transport
0.42	GO:2000490	negative regulation of hepatic stellate cell activation
0.41	GO:0032966	negative regulation of collagen biosynthetic process
0.41	GO:0010764	negative regulation of fibroblast migration
0.39	GO:0001666	response to hypoxia
0.38	GO:0019395	fatty acid oxidation
0.37	GO:0006979	response to oxidative stress
0.37	GO:0098869	cellular oxidant detoxification
0.36	GO:0046686	response to cadmium ion
0.35	GO:0050999	regulation of nitric-oxide synthase activity

0.79	GO:0019825	oxygen binding
0.79	GO:0005344	oxygen carrier activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.42	GO:0047888	fatty acid peroxidase activity
0.41	GO:0098809	nitrite reductase activity
0.38	GO:0004096	catalase activity
0.34	GO:0008941	nitric oxide dioxygenase activity
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0005515	protein binding

0.50	GO:0043025	neuronal cell body
0.49	GO:0016607	nuclear speck
0.49	GO:0043005	neuron projection
0.35	GO:0005737	cytoplasm
0.32	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.42	EC:1.11.1.3	GO:0047888
0.42	KEGG:R01703	GO:0047888

tr|Q8UUS8|Q8UUS8_DANRE
DMgamma2
Search

GPM6B

0.95	Neuronal membrane glycoprotein M6-b

0.51	GO:0030501	positive regulation of bone mineralization
0.51	GO:0051893	regulation of focal adhesion assembly
0.51	GO:0085029	extracellular matrix assembly
0.47	GO:0032956	regulation of actin cytoskeleton organization
0.38	GO:0051612	negative regulation of serotonin uptake
0.38	GO:2000009	negative regulation of protein localization to cell surface
0.37	GO:0001503	ossification
0.35	GO:0015031	protein transport
0.35	GO:0007399	nervous system development
0.34	GO:0030154	cell differentiation

0.36	GO:0045121	membrane raft
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q8UUT0|Q8UUT0_DANRE
DMgamma1
Search

0.95	Neuronal membrane glycoprotein M6-b

0.48	GO:0030501	positive regulation of bone mineralization
0.48	GO:0051893	regulation of focal adhesion assembly
0.48	GO:0085029	extracellular matrix assembly
0.45	GO:0032956	regulation of actin cytoskeleton organization
0.39	GO:0051612	negative regulation of serotonin uptake
0.39	GO:2000009	negative regulation of protein localization to cell surface
0.38	GO:0001503	ossification
0.36	GO:0007399	nervous system development
0.35	GO:0030154	cell differentiation
0.35	GO:0015031	protein transport

0.37	GO:0045121	membrane raft
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q8UUT3|Q8UUT3_DANRE
DMalpha2b
Search

0.92	Proteolipid protein DM alpha

0.46	GO:0030501	positive regulation of bone mineralization
0.46	GO:0051893	regulation of focal adhesion assembly
0.46	GO:0085029	extracellular matrix assembly
0.43	GO:0032956	regulation of actin cytoskeleton organization
0.41	GO:0042552	myelination
0.38	GO:0051612	negative regulation of serotonin uptake
0.37	GO:2000009	negative regulation of protein localization to cell surface
0.36	GO:0001503	ossification
0.35	GO:0030154	cell differentiation
0.34	GO:0015031	protein transport

0.34

GO:0042043

neurexin family protein binding

0.36	GO:0045121	membrane raft
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q8UUT4|Q8UUT4_DANRE
DMbeta1
Search

GPM6A

0.93	Proteolipid protein DM beta

0.53	GO:0001764	neuron migration
0.52	GO:0048863	stem cell differentiation
0.52	GO:0003407	neural retina development
0.51	GO:0031175	neuron projection development
0.49	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.46	GO:0051489	regulation of filopodium assembly
0.40	GO:0120034	positive regulation of plasma membrane bounded cell projection assembly
0.40	GO:0007416	synapse assembly
0.37	GO:0070588	calcium ion transmembrane transport

0.38	GO:0005262	calcium channel activity
0.34	GO:0005515	protein binding

0.53	GO:0044295	axonal growth cone
0.40	GO:0030175	filopodium
0.40	GO:0043025	neuronal cell body
0.40	GO:0043197	dendritic spine
0.36	GO:0070062	extracellular exosome
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q8UUT6|Q8UUT6_DANRE
DMalpha1
Search

0.93	Proteolipid protein DM alpha

0.47	GO:0030501	positive regulation of bone mineralization
0.47	GO:0051893	regulation of focal adhesion assembly
0.46	GO:0085029	extracellular matrix assembly
0.44	GO:0032956	regulation of actin cytoskeleton organization
0.42	GO:0042552	myelination
0.38	GO:0051612	negative regulation of serotonin uptake
0.37	GO:2000009	negative regulation of protein localization to cell surface
0.36	GO:0001503	ossification
0.34	GO:0015031	protein transport
0.34	GO:0030154	cell differentiation

0.34

GO:0042043

neurexin family protein binding

0.36	GO:0045121	membrane raft
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q8UUX9|Q8UUX9_DANRE
Guanylate cyclase activator 1C
Search

GUCA1C

0.97	Guanylate cyclase activating protein 3

0.84	GO:0031284	positive regulation of guanylate cyclase activity
0.61	GO:0007601	visual perception

0.85	GO:0008048	calcium sensitive guanylate cyclase activator activity
0.70	GO:0005509	calcium ion binding

0.30

GO:0044425

membrane part

tr|Q8UUY0|Q8UUY0_DANRE
Guanylate cyclase activator 1B
Search

GUCA1B

0.97	Guanylate cyclase activating protein 2

0.63	GO:0031284	positive regulation of guanylate cyclase activity
0.52	GO:0007601	visual perception
0.51	GO:0007602	phototransduction
0.35	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.35	GO:0007168	receptor guanylyl cyclase signaling pathway
0.35	GO:0007589	body fluid secretion
0.34	GO:0007267	cell-cell signaling

0.70	GO:0005509	calcium ion binding
0.64	GO:0008048	calcium sensitive guanylate cyclase activator activity

0.41	GO:0001750	photoreceptor outer segment
0.39	GO:0001917	photoreceptor inner segment
0.35	GO:0060170	ciliary membrane

sp|Q8UUZ1|MB212_DANRE
Protein mab-21-like 2
Search

MAB21L2

0.97	Mab-21 like 2

0.80	GO:0001654	eye development
0.79	GO:0010172	embryonic body morphogenesis
0.71	GO:0008284	positive regulation of cell proliferation
0.57	GO:0048701	embryonic cranial skeleton morphogenesis
0.55	GO:0090596	sensory organ morphogenesis
0.37	GO:0007399	nervous system development

0.36

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm

tr|Q8UUZ6|Q8UUZ6_DANRE
Alpha A crystallin
Search

CRYAA

0.96	Alpha-crystallin A chain

0.56	GO:0002088	lens development in camera-type eye
0.54	GO:0070141	response to UV-A
0.53	GO:0060561	apoptotic process involved in morphogenesis
0.52	GO:0048596	embryonic camera-type eye morphogenesis
0.51	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.51	GO:0007021	tubulin complex assembly
0.51	GO:0042542	response to hydrogen peroxide
0.51	GO:0030307	positive regulation of cell growth
0.50	GO:0001666	response to hypoxia
0.50	GO:0002064	epithelial cell development

0.85	GO:0005212	structural constituent of eye lens
0.44	GO:0046872	metal ion binding
0.43	GO:0051082	unfolded protein binding
0.37	GO:0042802	identical protein binding

0.46	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.36	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part

sp|Q8UVC1|INVS_DANRE
Inversin
Search

INVS

0.67

Inversin

0.73	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.69	GO:0072116	pronephros formation
0.67	GO:0036372	opsin transport
0.65	GO:0035844	cloaca development
0.63	GO:0060027	convergent extension involved in gastrulation
0.63	GO:0035050	embryonic heart tube development
0.62	GO:0010171	body morphogenesis
0.61	GO:0001736	establishment of planar polarity
0.61	GO:0061371	determination of heart left/right asymmetry
0.61	GO:0016055	Wnt signaling pathway

0.62

GO:0005516

calmodulin binding

0.58	GO:0005929	cilium
0.55	GO:0005856	cytoskeleton
0.42	GO:0005737	cytoplasm
0.40	GO:0099512	supramolecular fiber
0.39	GO:0120038	plasma membrane bounded cell projection part
0.38	GO:0005634	nucleus
0.37	GO:0044422	organelle part
0.30	GO:0016020	membrane

tr|Q8UVG6|Q8UVG6_DANRE
Cellular retinol-binding protein type II
Search

RBP2

0.97	Cellular retinol-binding protein type II

0.61	GO:0006776	vitamin A metabolic process
0.60	GO:0002138	retinoic acid biosynthetic process
0.40	GO:0033189	response to vitamin A
0.40	GO:0042572	retinol metabolic process
0.39	GO:0030852	regulation of granulocyte differentiation
0.34	GO:0008544	epidermis development
0.33	GO:0006886	intracellular protein transport
0.33	GO:0016192	vesicle-mediated transport

0.72	GO:0008289	lipid binding
0.38	GO:0043178	alcohol binding
0.37	GO:0019842	vitamin binding
0.33	GO:0016779	nucleotidyltransferase activity
0.32	GO:0005198	structural molecule activity

0.50	GO:0005829	cytosol
0.38	GO:0005811	lipid droplet
0.36	GO:0005654	nucleoplasm
0.33	GO:0030663	COPI-coated vesicle membrane
0.33	GO:0030117	membrane coat
0.33	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016779

tr|Q8UVG7|Q8UVG7_DANRE
Fatty acid binding protein 3, muscle and heart
Search

FABP3

0.81	Fatty acid-binding protein heart

0.49	GO:2001245	regulation of phosphatidylcholine biosynthetic process
0.49	GO:0055091	phospholipid homeostasis
0.49	GO:0044539	long-chain fatty acid import
0.48	GO:0046320	regulation of fatty acid oxidation
0.47	GO:0042632	cholesterol homeostasis
0.44	GO:0048513	animal organ development
0.44	GO:0032101	regulation of response to external stimulus
0.43	GO:0001964	startle response
0.43	GO:0007368	determination of left/right symmetry
0.42	GO:0061351	neural precursor cell proliferation

0.72	GO:0008289	lipid binding
0.48	GO:0033293	monocarboxylic acid binding
0.45	GO:0008092	cytoskeletal protein binding
0.35	GO:0005324	long-chain fatty acid transporter activity
0.32	GO:0016787	hydrolase activity

0.46	GO:0005615	extracellular space
0.41	GO:0043025	neuronal cell body
0.40	GO:0005911	cell-cell junction
0.39	GO:0042995	cell projection
0.36	GO:0043209	myelin sheath
0.36	GO:0071944	cell periphery
0.34	GO:0016528	sarcoplasm
0.34	GO:1903561	extracellular vesicle
0.34	GO:0005759	mitochondrial matrix
0.33	GO:0005829	cytosol

0.32

GO:0016787

sp|Q8UVJ6|VANG2_DANRE
Vang-like protein 2
Search

VANGL2

0.92	VANGL planar cell polarity protein 2

0.70	GO:0007275	multicellular organism development
0.56	GO:0060028	convergent extension involved in axis elongation
0.56	GO:0036342	post-anal tail morphogenesis
0.56	GO:0060071	Wnt signaling pathway, planar cell polarity pathway
0.55	GO:0001736	establishment of planar polarity
0.53	GO:0030111	regulation of Wnt signaling pathway
0.53	GO:0060601	lateral sprouting from an epithelium
0.53	GO:0060600	dichotomous subdivision of an epithelial terminal unit
0.52	GO:0090178	regulation of establishment of planar polarity involved in neural tube closure
0.52	GO:0007163	establishment or maintenance of cell polarity

0.35

GO:0005515

protein binding

0.55	GO:0016328	lateral plasma membrane
0.53	GO:0060187	cell pole
0.51	GO:0097517	contractile actin filament bundle
0.50	GO:0042641	actomyosin
0.49	GO:0016323	basolateral plasma membrane
0.49	GO:0016324	apical plasma membrane
0.48	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.47	GO:0005911	cell-cell junction
0.30	GO:0016021	integral component of membrane

sp|Q8UVK2|SPT6H_DANRE
Transcription elongation factor SPT6
Search

SUPT6H

0.73	Transcription elongation factor SPT6

0.74	GO:0032784	regulation of DNA-templated transcription, elongation
0.69	GO:0006357	regulation of transcription by RNA polymerase II
0.62	GO:0061086	negative regulation of histone H3-K27 methylation
0.59	GO:0006414	translational elongation
0.57	GO:0010793	regulation of mRNA export from nucleus
0.56	GO:0045191	regulation of isotype switching
0.56	GO:0006351	transcription, DNA-templated
0.55	GO:0051147	regulation of muscle cell differentiation
0.53	GO:0050684	regulation of mRNA processing
0.51	GO:0045893	positive regulation of transcription, DNA-templated

0.84	GO:0000991	transcription factor activity, core RNA polymerase II binding
0.60	GO:0003746	translation elongation factor activity
0.55	GO:0042393	histone binding
0.54	GO:0003677	DNA binding
0.47	GO:0031491	nucleosome binding
0.40	GO:0003700	DNA binding transcription factor activity

0.59	GO:0005634	nucleus
0.48	GO:0035327	transcriptionally active chromatin
0.42	GO:0031974	membrane-enclosed lumen
0.40	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q8UVX0|PIWL1_DANRE
Piwi-like protein 1
Search

PIWIL1

0.91	Piwi like RNA-mediated gene silencing 1

0.80	GO:0007286	spermatid development
0.79	GO:0031047	gene silencing by RNA
0.60	GO:0034587	piRNA metabolic process
0.56	GO:0010529	negative regulation of transposition
0.54	GO:0043486	histone exchange
0.53	GO:0006997	nucleus organization
0.50	GO:0006323	DNA packaging
0.48	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.42	GO:0009653	anatomical structure morphogenesis
0.38	GO:0051321	meiotic cell cycle

0.85	GO:0034584	piRNA binding
0.51	GO:0003727	single-stranded RNA binding
0.51	GO:0019901	protein kinase binding
0.50	GO:0003729	mRNA binding
0.48	GO:0004521	endoribonuclease activity
0.34	GO:0046872	metal ion binding

0.56	GO:0033391	chromatoid body
0.55	GO:0097433	dense body
0.54	GO:0005845	mRNA cap binding complex
0.53	GO:0005844	polysome
0.48	GO:0043186	P granule
0.44	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|Q8UVY8|Q8UVY8_DANRE
CCAAT/enhancer binding protein (C/EBP), gamma
Search

CEBPG

0.96	CCAAT/enhancer binding protein gamma

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0043353	enucleate erythrocyte differentiation
0.56	GO:0045078	positive regulation of interferon-gamma biosynthetic process
0.55	GO:0042267	natural killer cell mediated cytotoxicity
0.54	GO:0045739	positive regulation of DNA repair
0.53	GO:0030183	B cell differentiation
0.51	GO:0006366	transcription by RNA polymerase II
0.50	GO:0051254	positive regulation of RNA metabolic process

0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0042803	protein homodimerization activity
0.50	GO:0046982	protein heterodimerization activity
0.48	GO:0008134	transcription factor binding
0.38	GO:0044374	sequence-specific DNA binding, bending
0.33	GO:0031490	chromatin DNA binding
0.32	GO:0005216	ion channel activity
0.32	GO:0046872	metal ion binding

0.48	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

tr|Q8UVZ0|Q8UVZ0_DANRE
CCAAT/enhancer binding protein (C/EBP), beta
Search

CEBPB

0.89	CCAAT enhancer-binding protein beta 2

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0001889	liver development
0.51	GO:0009617	response to bacterium
0.51	GO:0045600	positive regulation of fat cell differentiation
0.51	GO:0045669	positive regulation of osteoblast differentiation
0.50	GO:0045444	fat cell differentiation
0.50	GO:0001878	response to yeast
0.49	GO:0044030	regulation of DNA methylation

0.61	GO:0003700	DNA binding transcription factor activity
0.49	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.48	GO:0035035	histone acetyltransferase binding
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0019900	kinase binding
0.47	GO:0042826	histone deacetylase binding
0.47	GO:0042803	protein homodimerization activity
0.46	GO:0001047	core promoter binding
0.45	GO:0003682	chromatin binding
0.45	GO:0044389	ubiquitin-like protein ligase binding

0.47	GO:0016363	nuclear matrix
0.45	GO:0000779	condensed chromosome, centromeric region
0.45	GO:0005654	nucleoplasm
0.44	GO:0000790	nuclear chromatin
0.41	GO:0090575	RNA polymerase II transcription factor complex
0.36	GO:0005737	cytoplasm
0.35	GO:0005730	nucleolus
0.32	GO:0005886	plasma membrane

tr|Q8UVZ1|Q8UVZ1_DANRE
CCAAT/enhancer binding protein (C/EBP), alpha
Search

0.96	CCAAT enhancer binding protein alpha

0.60	GO:0030851	granulocyte differentiation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0001889	liver development
0.54	GO:0030225	macrophage differentiation
0.52	GO:0006366	transcription by RNA polymerase II
0.51	GO:0051254	positive regulation of RNA metabolic process
0.50	GO:0010557	positive regulation of macromolecule biosynthetic process
0.50	GO:0031328	positive regulation of cellular biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.51	GO:0000987	proximal promoter sequence-specific DNA binding
0.47	GO:0042803	protein homodimerization activity
0.46	GO:0019900	kinase binding
0.45	GO:0035035	histone acetyltransferase binding
0.44	GO:0001046	core promoter sequence-specific DNA binding
0.44	GO:0042826	histone deacetylase binding
0.42	GO:0003682	chromatin binding
0.42	GO:0044389	ubiquitin-like protein ligase binding

0.49	GO:0005654	nucleoplasm
0.44	GO:0016363	nuclear matrix
0.42	GO:0000779	condensed chromosome, centromeric region
0.42	GO:0090575	RNA polymerase II transcription factor complex
0.42	GO:0000790	nuclear chromatin
0.35	GO:0005737	cytoplasm
0.32	GO:0005730	nucleolus
0.32	GO:0005886	plasma membrane

sp|Q8UW00|HN1BB_DANRE
Hepatocyte nuclear factor 1-beta-B
Search

HNF1B

0.95	Hepatocyte nuclear factor 1-beta-B

0.73	GO:0045893	positive regulation of transcription, DNA-templated
0.58	GO:0035565	regulation of pronephros size
0.58	GO:0061296	negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
0.57	GO:0072181	mesonephric duct formation
0.57	GO:1900211	regulation of mesenchymal cell apoptotic process involved in metanephros development
0.57	GO:0039020	pronephric nephron tubule development
0.57	GO:0061017	hepatoblast differentiation
0.56	GO:0072095	regulation of branch elongation involved in ureteric bud branching
0.56	GO:0060677	ureteric bud elongation
0.56	GO:0072217	negative regulation of metanephros development

0.55	GO:0003677	DNA binding
0.53	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.52	GO:0001067	regulatory region nucleic acid binding
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0046982	protein heterodimerization activity
0.38	GO:0032403	protein complex binding
0.33	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding

0.61	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.47	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.33	GO:0001750	photoreceptor outer segment
0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q8UW07|Q8UW07_DANRE
Cytochrome P450
Search

tr|Q8UWD5|Q8UWD5_DANRE
BCL2-like 10 (Apoptosis facilitator)
Search

BCL2L10

0.97	Anti-apoptotic protein NR-13

0.74	GO:0042981	regulation of apoptotic process
0.58	GO:0090504	epiboly
0.58	GO:0051279	regulation of release of sequestered calcium ion into cytosol
0.58	GO:0001756	somitogenesis
0.57	GO:0019722	calcium-mediated signaling
0.56	GO:0007369	gastrulation
0.54	GO:0043069	negative regulation of programmed cell death
0.43	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand
0.42	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.41	GO:1902532	negative regulation of intracellular signal transduction

0.40

GO:0005515

protein binding

0.45	GO:0005739	mitochondrion
0.41	GO:0031968	organelle outer membrane
0.30	GO:0016021	integral component of membrane

sp|Q8UWJ4|DLLD_DANRE
Delta-like protein D
Search

0.74	Delta-like protein 1

0.70	GO:0021688	cerebellar molecular layer formation
0.70	GO:0097102	endothelial tip cell fate specification
0.70	GO:0060853	Notch signaling pathway involved in arterial endothelial cell fate commitment
0.69	GO:0045608	negative regulation of inner ear auditory receptor cell differentiation
0.68	GO:0021693	cerebellar Purkinje cell layer structural organization
0.68	GO:0048633	positive regulation of skeletal muscle tissue growth
0.68	GO:0048630	skeletal muscle tissue growth
0.68	GO:0046331	lateral inhibition
0.67	GO:0007386	compartment pattern specification
0.67	GO:0002315	marginal zone B cell differentiation

0.70	GO:0005509	calcium ion binding
0.67	GO:0030957	Tat protein binding
0.64	GO:0097110	scaffold protein binding
0.64	GO:0005112	Notch binding

0.61	GO:0016324	apical plasma membrane
0.60	GO:0098857	membrane microdomain
0.60	GO:0005912	adherens junction
0.55	GO:0031410	cytoplasmic vesicle
0.43	GO:0005887	integral component of plasma membrane
0.43	GO:0005576	extracellular region
0.41	GO:0005634	nucleus

tr|Q8UWM1|Q8UWM1_DANRE
Hexosyltransferase
Search

0.55	Hexosyltransferase

0.74	GO:0006486	protein glycosylation
0.48	GO:0030311	poly-N-acetyllactosamine biosynthetic process

0.80	GO:0008378	galactosyltransferase activity
0.48	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity

0.73	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.80

GO:0008378

tr|Q8WM94|Q8WM94_DANRE
Novel protein similar to MHC class II alpha chain
Search

0.42	HLA class II histocompatibility antigen, DP alpha chain

0.75	GO:0019882	antigen processing and presentation
0.73	GO:0006955	immune response

0.75	GO:0042613	MHC class II protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q90257|ES1_DANRE
ES1 protein, mitochondrial
Search

0.45	ES1 protein homolog, mitochondrial

0.51

GO:0070584

mitochondrion morphogenesis

0.38

GO:0016829

lyase activity

0.57	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

0.38

EC:4

GO:0016829

sp|Q90259|ASL1A_DANRE
Achaete-scute homolog 1a
Search

0.28	Transcriptional regulator

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.55	GO:0035270	endocrine system development
0.55	GO:0030902	hindbrain development
0.53	GO:0061549	sympathetic ganglion development
0.53	GO:0009790	embryo development
0.52	GO:0048699	generation of neurons
0.50	GO:0048565	digestive tract development
0.50	GO:0030900	forebrain development
0.50	GO:0048469	cell maturation
0.50	GO:0002065	columnar/cuboidal epithelial cell differentiation

0.68	GO:0046983	protein dimerization activity
0.55	GO:0003677	DNA binding
0.51	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0001067	regulatory region nucleic acid binding
0.45	GO:0043425	bHLH transcription factor binding
0.43	GO:0000989	transcription factor activity, transcription factor binding
0.42	GO:0003682	chromatin binding

0.45	GO:0090575	RNA polymerase II transcription factor complex
0.43	GO:0043025	neuronal cell body
0.36	GO:0005737	cytoplasm

sp|Q90260|ASL1B_DANRE
Achaete-scute homolog 1b
Search

ASCL1

0.29	Transcriptional regulator

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.57	GO:0035270	endocrine system development
0.57	GO:0030902	hindbrain development
0.55	GO:0061549	sympathetic ganglion development
0.54	GO:0003359	noradrenergic neuron fate commitment
0.53	GO:0060165	regulation of timing of subpallium neuron differentiation
0.53	GO:0061100	lung neuroendocrine cell differentiation
0.53	GO:0061103	carotid body glomus cell differentiation
0.53	GO:0061102	stomach neuroendocrine cell differentiation
0.52	GO:0060163	subpallium neuron fate commitment

0.68	GO:0046983	protein dimerization activity
0.56	GO:0070888	E-box binding
0.54	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0043425	bHLH transcription factor binding
0.47	GO:0000989	transcription factor activity, transcription factor binding
0.46	GO:0003682	chromatin binding
0.36	GO:0042802	identical protein binding

0.48	GO:0043025	neuronal cell body
0.47	GO:0090575	RNA polymerase II transcription factor complex
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q90264|Q90264_DANRE
Empty spiracles homeobox 2
Search

EMX2

0.95	Empty spiracles homeobox 2

0.67	GO:0007420	brain development
0.65	GO:0030182	neuron differentiation
0.60	GO:0003002	regionalization
0.59	GO:0061351	neural precursor cell proliferation
0.57	GO:0072001	renal system development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0016477	cell migration
0.55	GO:0120036	plasma membrane bounded cell projection organization

0.64

GO:0043565

sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.41	GO:0043233	organelle lumen
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.38	GO:0044446	intracellular organelle part

sp|Q90267|OTX1A_DANRE
Homeobox protein OTX1 A
Search

OTX1

0.96	Orthodenticle homeobox 1

0.70	GO:0007275	multicellular organism development
0.61	GO:0060322	head development
0.59	GO:0006366	transcription by RNA polymerase II
0.59	GO:0045944	positive regulation of transcription by RNA polymerase II
0.59	GO:0009653	anatomical structure morphogenesis
0.43	GO:0060429	epithelium development
0.39	GO:0120036	plasma membrane bounded cell projection organization
0.39	GO:0048468	cell development
0.38	GO:0006935	chemotaxis
0.38	GO:0006928	movement of cell or subcellular component

0.65	GO:0043565	sequence-specific DNA binding
0.64	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.61	GO:0001012	RNA polymerase II regulatory region DNA binding
0.57	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.41	GO:0030426	growth cone
0.36	GO:0043234	protein complex

sp|Q90268|PAX2A_DANRE
Paired box protein Pax-2a
Search

PAX2

0.93	LOW QUALITY PROTEIN: paired box protein Pax-2

0.69	GO:0007275	multicellular organism development
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:0006355	regulation of transcription, DNA-templated
0.54	GO:0045918	negative regulation of cytolysis
0.52	GO:2000378	negative regulation of reactive oxygen species metabolic process
0.51	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.51	GO:0002009	morphogenesis of an epithelium
0.50	GO:0001763	morphogenesis of a branching structure
0.50	GO:0050679	positive regulation of epithelial cell proliferation
0.48	GO:0090066	regulation of anatomical structure size

0.54	GO:0003677	DNA binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0008134	transcription factor binding
0.39	GO:0016175	superoxide-generating NADPH oxidase activity
0.37	GO:0070742	C2H2 zinc finger domain binding
0.36	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.52	GO:0034451	centriolar satellite
0.46	GO:0005794	Golgi apparatus
0.44	GO:0070013	intracellular organelle lumen
0.37	GO:0005764	lysosome
0.37	GO:0032993	protein-DNA complex
0.35	GO:0043234	protein complex

0.39

EC:1.6.3

GO:0016175

sp|Q90270|PO5F1_DANRE
POU domain, class 5, transcription factor 1
Search

POU5F1

0.46	POU domain, class 5, transcription factor 1

0.57	GO:0097659	nucleic acid-templated transcription
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0010467	gene expression
0.52	GO:0034645	cellular macromolecule biosynthetic process
0.47	GO:0007420	brain development
0.40	GO:0007398	ectoderm development
0.40	GO:0001706	endoderm formation
0.39	GO:0007498	mesoderm development

0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.38	GO:0035326	enhancer binding
0.38	GO:0019955	cytokine binding
0.38	GO:0003682	chromatin binding
0.38	GO:0046982	protein heterodimerization activity
0.37	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding
0.37	GO:0003690	double-stranded DNA binding
0.36	GO:0003714	transcription corepressor activity
0.35	GO:0031625	ubiquitin protein ligase binding

0.61	GO:0005634	nucleus
0.37	GO:0000785	chromatin
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0017053	transcriptional repressor complex
0.35	GO:0005667	transcription factor complex
0.33	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q90271|RARAA_DANRE
Retinoic acid receptor alpha-A
Search

RARA

0.92	Retinoic acid receptor RAR-alpha

0.85	GO:0048384	retinoic acid receptor signaling pathway
0.77	GO:0043401	steroid hormone mediated signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0060010	Sertoli cell fate commitment
0.53	GO:0003417	growth plate cartilage development
0.53	GO:0055012	ventricular cardiac muscle cell differentiation
0.53	GO:0032526	response to retinoic acid

0.85	GO:0003708	retinoic acid receptor activity
0.78	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.52	GO:0043422	protein kinase B binding
0.51	GO:0001972	retinoic acid binding
0.51	GO:0051393	alpha-actinin binding
0.49	GO:0051018	protein kinase A binding
0.49	GO:0031490	chromatin DNA binding
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding

0.60	GO:0005634	nucleus
0.48	GO:0043025	neuronal cell body
0.48	GO:0030425	dendrite
0.46	GO:0015629	actin cytoskeleton
0.45	GO:0000785	chromatin
0.44	GO:0070013	intracellular organelle lumen
0.44	GO:0005829	cytosol
0.39	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0009986	cell surface
0.30	GO:0016020	membrane

tr|Q90274|Q90274_DANRE
Sna-1 protein
Search

0.91	Snail family transcriptional repressor 1

0.63	GO:0001837	epithelial to mesenchymal transition
0.61	GO:0010957	negative regulation of vitamin D biosynthetic process
0.60	GO:2000810	regulation of bicellular tight junction assembly
0.60	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
0.59	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.59	GO:0007369	gastrulation
0.58	GO:0016477	cell migration
0.58	GO:0001649	osteoblast differentiation
0.56	GO:0003007	heart morphogenesis
0.56	GO:0030335	positive regulation of cell migration

0.57	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0003676	nucleic acid binding
0.49	GO:0019900	kinase binding
0.48	GO:0051059	NF-kappaB binding
0.41	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.39	GO:0003682	chromatin binding
0.34	GO:0005507	copper ion binding

0.51	GO:0005721	pericentric heterochromatin
0.49	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.42	GO:0070013	intracellular organelle lumen
0.35	GO:0005667	transcription factor complex

sp|Q90275|CADH2_DANRE
Cadherin-2
Search

CDH2

0.93	Cadherin 2, type 1 preproprotein (Predicted)

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.70	GO:0009966	regulation of signal transduction
0.57	GO:0044331	cell-cell adhesion mediated by cadherin
0.56	GO:0097150	neuronal stem cell population maintenance
0.56	GO:1902897	regulation of postsynaptic density protein 95 clustering
0.55	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly
0.55	GO:2000809	positive regulation of synaptic vesicle clustering
0.55	GO:0070445	regulation of oligodendrocyte progenitor proliferation
0.54	GO:0060019	radial glial cell differentiation
0.53	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

0.70	GO:0005509	calcium ion binding
0.54	GO:0045295	gamma-catenin binding
0.53	GO:0045294	alpha-catenin binding
0.51	GO:0019903	protein phosphatase binding
0.51	GO:0008013	beta-catenin binding
0.49	GO:0019901	protein kinase binding
0.47	GO:0042802	identical protein binding
0.35	GO:0050998	nitric-oxide synthase binding
0.34	GO:0050840	extracellular matrix binding
0.34	GO:0045296	cadherin binding

0.56	GO:0005886	plasma membrane
0.55	GO:0014704	intercalated disc
0.52	GO:0005913	cell-cell adherens junction
0.51	GO:0014069	postsynaptic density
0.51	GO:0030027	lamellipodium
0.50	GO:0098857	membrane microdomain
0.50	GO:0045177	apical part of cell
0.50	GO:0030864	cortical actin cytoskeleton
0.49	GO:0009986	cell surface
0.48	GO:0019898	extrinsic component of membrane

sp|Q90413|FGFR4_DANRE
Fibroblast growth factor receptor 4
Search

FGFR4

0.69	Fibroblast growth factor receptor

0.82	GO:0008543	fibroblast growth factor receptor signaling pathway
0.77	GO:0008284	positive regulation of cell proliferation
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.50	GO:0070857	regulation of bile acid biosynthetic process
0.50	GO:0010715	regulation of extracellular matrix disassembly
0.49	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.49	GO:0046777	protein autophosphorylation
0.48	GO:2000573	positive regulation of DNA biosynthetic process
0.46	GO:0045862	positive regulation of proteolysis
0.46	GO:0016477	cell migration

0.85	GO:0005007	fibroblast growth factor-activated receptor activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0017134	fibroblast growth factor binding
0.43	GO:1901681	sulfur compound binding
0.37	GO:0042802	identical protein binding
0.37	GO:0004908	interleukin-1 receptor activity
0.35	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity

0.47	GO:0030133	transport vesicle
0.46	GO:0005783	endoplasmic reticulum
0.46	GO:0005911	cell-cell junction
0.45	GO:0005794	Golgi apparatus
0.44	GO:0005887	integral component of plasma membrane
0.39	GO:0005768	endosome
0.35	GO:0009986	cell surface
0.34	GO:0005576	extracellular region
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005764	lysosome

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

sp|Q90415|RXRAB_DANRE
Retinoic acid receptor RXR-alpha-B
Search

RXRA

0.93	Retinoic acid receptor RXR-alpha-B

0.79	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0097659	nucleic acid-templated transcription
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0010467	gene expression
0.53	GO:0034645	cellular macromolecule biosynthetic process
0.46	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
0.46	GO:0048384	retinoic acid receptor signaling pathway
0.46	GO:0060687	regulation of branching involved in prostate gland morphogenesis

0.80	GO:0003707	steroid hormone receptor activity
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.46	GO:0050692	DBD domain binding
0.46	GO:0050693	LBD domain binding
0.46	GO:0042809	vitamin D receptor binding
0.45	GO:0001972	retinoic acid binding
0.45	GO:0016922	ligand-dependent nuclear receptor binding
0.44	GO:0031490	chromatin DNA binding

0.61	GO:0005634	nucleus
0.43	GO:0043235	receptor complex
0.42	GO:0005667	transcription factor complex
0.41	GO:0000785	chromatin
0.40	GO:0070013	intracellular organelle lumen
0.36	GO:0030424	axon

sp|Q90416|RXRGA_DANRE
Retinoic acid receptor RXR-gamma-A
Search

0.80	Retinoid x receptor gamma a

0.79	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0048384	retinoic acid receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0051289	protein homotetramerization
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0051254	positive regulation of RNA metabolic process
0.51	GO:0010557	positive regulation of macromolecule biosynthetic process
0.51	GO:0031328	positive regulation of cellular biosynthetic process

0.80	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding
0.38	GO:0050692	DBD domain binding
0.38	GO:0050693	LBD domain binding
0.38	GO:0042809	vitamin D receptor binding
0.38	GO:0001972	retinoic acid binding

0.61	GO:0005634	nucleus
0.36	GO:0043235	receptor complex
0.36	GO:0005667	transcription factor complex
0.35	GO:0000785	chromatin
0.35	GO:0043233	organelle lumen

sp|Q90417|RXRBB_DANRE
Retinoic acid receptor RXR-beta-B
Search

0.83	Retinoic acid receptor RXR-beta-B

0.79	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0097659	nucleic acid-templated transcription
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0010467	gene expression
0.53	GO:0034645	cellular macromolecule biosynthetic process
0.44	GO:0048384	retinoic acid receptor signaling pathway
0.41	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
0.41	GO:0060687	regulation of branching involved in prostate gland morphogenesis

0.80	GO:0003707	steroid hormone receptor activity
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.42	GO:0005501	retinoid binding
0.41	GO:0050692	DBD domain binding
0.41	GO:0050693	LBD domain binding
0.41	GO:0042809	vitamin D receptor binding
0.41	GO:0016922	ligand-dependent nuclear receptor binding
0.40	GO:0031490	chromatin DNA binding

0.61	GO:0005634	nucleus
0.39	GO:0005667	transcription factor complex
0.39	GO:0043235	receptor complex
0.38	GO:0000785	chromatin
0.37	GO:0030424	axon
0.37	GO:0070013	intracellular organelle lumen
0.36	GO:0030426	growth cone
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q90419|TWHH_DANRE
Tiggy-winkle hedgehog protein
Search

SHH

0.72	Sonic hedgehog protein A

0.74	GO:0016539	intein-mediated protein splicing
0.74	GO:0007267	cell-cell signaling
0.69	GO:0007275	multicellular organism development
0.52	GO:0061189	positive regulation of sclerotome development
0.51	GO:0060782	regulation of mesenchymal cell proliferation involved in prostate gland development
0.51	GO:2000062	negative regulation of ureter smooth muscle cell differentiation
0.51	GO:2000357	negative regulation of kidney smooth muscle cell differentiation
0.51	GO:2000358	positive regulation of kidney smooth muscle cell differentiation
0.51	GO:2000063	positive regulation of ureter smooth muscle cell differentiation
0.51	GO:1905327	tracheoesophageal septum formation

0.59	GO:0008233	peptidase activity
0.51	GO:0046872	metal ion binding
0.50	GO:0043237	laminin-1 binding
0.50	GO:0005113	patched binding
0.45	GO:0005539	glycosaminoglycan binding
0.37	GO:0016015	morphogen activity

0.68	GO:0005615	extracellular space
0.53	GO:0005886	plasma membrane
0.46	GO:0098857	membrane microdomain
0.45	GO:0005578	proteinaceous extracellular matrix
0.45	GO:0009986	cell surface
0.35	GO:0005622	intracellular
0.34	GO:0043025	neuronal cell body
0.34	GO:0012505	endomembrane system
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon

0.59

GO:0008233

sp|Q90421|LHX3_DANRE
LIM/homeobox protein Lhx3
Search

LHX3

0.95	Lim homeobox protein 3 splice variant

0.70	GO:0021526	medial motor column neuron differentiation
0.65	GO:0008045	motor neuron axon guidance
0.63	GO:0021521	ventral spinal cord interneuron specification
0.62	GO:0001890	placenta development
0.60	GO:0043066	negative regulation of apoptotic process
0.59	GO:0021527	spinal cord association neuron differentiation
0.59	GO:0021520	spinal cord motor neuron cell fate specification
0.58	GO:0021983	pituitary gland development
0.58	GO:0045944	positive regulation of transcription by RNA polymerase II
0.56	GO:0048839	inner ear development

0.63	GO:0043565	sequence-specific DNA binding
0.56	GO:0001085	RNA polymerase II transcription factor binding
0.55	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0046872	metal ion binding
0.53	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.52	GO:0005667	transcription factor complex

sp|Q90423|HXB1B_DANRE
Homeobox protein Hox-B1b
Search

0.80	Homeobox protein Hox-B1

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0021598	abducens nerve morphogenesis
0.55	GO:0060876	semicircular canal formation
0.54	GO:0042473	outer ear morphogenesis
0.54	GO:0007634	optokinetic behavior
0.54	GO:0021603	cranial nerve formation
0.53	GO:0048702	embryonic neurocranium morphogenesis
0.53	GO:0090103	cochlea morphogenesis

0.63	GO:0043565	sequence-specific DNA binding
0.47	GO:0042802	identical protein binding
0.34	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part

tr|Q90426|Q90426_DANRE
Odorant receptor
Search

0.40	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:1903955	positive regulation of protein targeting to mitochondrion

0.76	GO:0004984	olfactory receptor activity
0.64	GO:0004930	G-protein coupled receptor activity
0.34	GO:0005549	odorant binding

0.51	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q90428|Q90428_DANRE
Odorant receptor 9.2
Search

0.41	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.63	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005549	odorant binding

0.50	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q90435|PO4F3_DANRE
POU domain, class 4, transcription factor 3
Search

POU4F3

0.56	POU domain, class 4, transcription factor 3

0.72	GO:0007605	sensory perception of sound
0.69	GO:0007423	sensory organ development
0.63	GO:0031290	retinal ganglion cell axon guidance
0.62	GO:0050885	neuromuscular process controlling balance
0.62	GO:0048675	axon extension
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0006355	regulation of transcription, DNA-templated
0.56	GO:0021562	vestibulocochlear nerve development
0.56	GO:0009888	tissue development
0.55	GO:1902870	negative regulation of amacrine cell differentiation

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.57	GO:0001012	RNA polymerase II regulatory region DNA binding
0.54	GO:0003690	double-stranded DNA binding
0.52	GO:1990841	promoter-specific chromatin binding
0.50	GO:0003714	transcription corepressor activity
0.37	GO:0003713	transcription coactivator activity
0.35	GO:0005515	protein binding
0.34	GO:0035326	enhancer binding
0.33	GO:0003697	single-stranded DNA binding

0.61	GO:0005634	nucleus
0.51	GO:0070013	intracellular organelle lumen
0.46	GO:0044446	intracellular organelle part
0.41	GO:0005737	cytoplasm
0.34	GO:0005667	transcription factor complex
0.34	GO:0043005	neuron projection
0.34	GO:0005886	plasma membrane
0.33	GO:0005694	chromosome

sp|Q90456|MR1BA_DANRE
Melatonin receptor type 1B-A (Fragment)
Search

0.92	Melatonin receptor subtype one c

0.67	GO:0007186	G-protein coupled receptor signaling pathway
0.42	GO:0007623	circadian rhythm
0.38	GO:0050796	regulation of insulin secretion
0.38	GO:1900542	regulation of purine nucleotide metabolic process
0.38	GO:0042593	glucose homeostasis
0.37	GO:0030804	positive regulation of cyclic nucleotide biosynthetic process
0.35	GO:0051198	negative regulation of coenzyme metabolic process
0.35	GO:0046325	negative regulation of glucose import
0.34	GO:0045980	negative regulation of nucleotide metabolic process
0.34	GO:0043470	regulation of carbohydrate catabolic process

0.82	GO:0008502	melatonin receptor activity
0.38	GO:0042562	hormone binding
0.33	GO:0033218	amide binding
0.33	GO:0005515	protein binding
0.33	GO:0097159	organic cyclic compound binding
0.32	GO:0008144	drug binding
0.31	GO:1901363	heterocyclic compound binding

0.36	GO:0043235	receptor complex
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q90459|CCND1_DANRE
G1/S-specific cyclin-D1
Search

CCND1

0.97	G1/S-specific cyclin-D1

0.67	GO:0007049	cell cycle
0.56	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.55	GO:0070141	response to UV-A
0.55	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.55	GO:1901992	positive regulation of mitotic cell cycle phase transition
0.54	GO:0044783	G1 DNA damage checkpoint
0.54	GO:0071157	negative regulation of cell cycle arrest
0.54	GO:1902807	negative regulation of cell cycle G1/S phase transition
0.53	GO:0033601	positive regulation of mammary gland epithelial cell proliferation
0.53	GO:1902751	positive regulation of cell cycle G2/M phase transition

0.52	GO:0070064	proline-rich region binding
0.51	GO:0003714	transcription corepressor activity
0.51	GO:0019901	protein kinase binding
0.51	GO:0042826	histone deacetylase binding
0.49	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.46	GO:0008134	transcription factor binding
0.43	GO:0004672	protein kinase activity
0.38	GO:0032403	protein complex binding
0.35	GO:0060089	molecular transducer activity
0.34	GO:0008146	sulfotransferase activity

0.61	GO:0005634	nucleus
0.55	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.51	GO:0017053	transcriptional repressor complex
0.49	GO:0005923	bicellular tight junction
0.46	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.39	GO:0005829	cytosol
0.38	GO:0005694	chromosome
0.38	GO:0012505	endomembrane system
0.37	GO:0031090	organelle membrane

0.49

GO:0016538

sp|Q90460|C166A_DANRE
CD166 antigen homolog A
Search

0.97	Activated leukocyte cell adhesion molecule a

0.51	GO:0060385	axonogenesis involved in innervation
0.50	GO:0031290	retinal ganglion cell axon guidance
0.49	GO:0021885	forebrain cell migration
0.42	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.41	GO:0008045	motor neuron axon guidance
0.40	GO:0002250	adaptive immune response
0.38	GO:0060536	cartilage morphogenesis
0.38	GO:0048703	embryonic viscerocranium morphogenesis
0.37	GO:0060042	retina morphogenesis in camera-type eye
0.37	GO:0001947	heart looping

0.49

GO:0042802

identical protein binding

0.51	GO:0030424	axon
0.43	GO:0036477	somatodendritic compartment
0.42	GO:0042101	T cell receptor complex
0.42	GO:0001772	immunological synapse
0.40	GO:0009897	external side of plasma membrane
0.40	GO:0044297	cell body
0.39	GO:0120038	plasma membrane bounded cell projection part
0.38	GO:0031226	intrinsic component of plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q90466|Q90466_DANRE
HER-4 protein
Search

HES5

0.88	Hairy and enhancer of split 5

0.55	GO:0006351	transcription, DNA-templated
0.54	GO:0006355	regulation of transcription, DNA-templated
0.50	GO:0048936	peripheral nervous system neuron axonogenesis
0.43	GO:0007379	segment specification
0.42	GO:0042668	auditory receptor cell fate determination
0.42	GO:2000981	negative regulation of inner ear receptor cell differentiation
0.42	GO:0072049	comma-shaped body morphogenesis
0.42	GO:0072047	proximal/distal pattern formation involved in nephron development
0.42	GO:0007219	Notch signaling pathway
0.42	GO:0072050	S-shaped body morphogenesis

0.68	GO:0046983	protein dimerization activity
0.52	GO:0003677	DNA binding
0.40	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0003682	chromatin binding
0.35	GO:0008134	transcription factor binding

0.58	GO:0005634	nucleus
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q90469|HXDAA_DANRE
Homeobox protein Hox-D10a
Search

HOXD10

0.97	homeobox protein Hox-D10

0.57	GO:0021520	spinal cord motor neuron cell fate specification
0.57	GO:0048935	peripheral nervous system neuron development
0.56	GO:0035137	hindlimb morphogenesis
0.56	GO:0035136	forelimb morphogenesis
0.56	GO:0009954	proximal/distal pattern formation
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0050905	neuromuscular process
0.55	GO:0008344	adult locomotory behavior

0.63	GO:0043565	sequence-specific DNA binding
0.53	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.52	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003682	chromatin binding
0.49	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.53	GO:0036464	cytoplasmic ribonucleoprotein granule
0.48	GO:0005829	cytosol
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part

sp|Q90470|HXDBA_DANRE
Homeobox protein Hox-D11a
Search

0.93	homeobox protein Hox-D11

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.40	GO:0007275	multicellular organism development
0.39	GO:0001759	organ induction
0.38	GO:0006351	transcription, DNA-templated
0.37	GO:1902680	positive regulation of RNA biosynthetic process
0.36	GO:0009653	anatomical structure morphogenesis
0.32	GO:0032332	positive regulation of chondrocyte differentiation
0.32	GO:0007338	single fertilization

0.63	GO:0043565	sequence-specific DNA binding
0.38	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.38	GO:0001012	RNA polymerase II regulatory region DNA binding
0.37	GO:0003690	double-stranded DNA binding

0.60	GO:0005634	nucleus
0.40	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.36	GO:0005829	cytosol

sp|Q90471|HXDCA_DANRE
Homeobox protein Hox-D12a
Search

HOXD12

0.96	Homeobox protein Hox-C12 isoform B

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0042733	embryonic digit morphogenesis
0.51	GO:0001501	skeletal system development
0.50	GO:0007389	pattern specification process
0.37	GO:0006351	transcription, DNA-templated

0.64	GO:0043565	sequence-specific DNA binding
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex

sp|Q90472|HXDDA_DANRE
Homeobox protein Hox-D13a
Search

0.95	LOW QUALITY PROTEIN: homeobox protein Hox-A13

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0060526	prostate glandular acinus morphogenesis
0.51	GO:0060442	branching involved in prostate gland morphogenesis
0.51	GO:0060687	regulation of branching involved in prostate gland morphogenesis
0.51	GO:0060602	branch elongation of an epithelium
0.50	GO:0060571	morphogenesis of an epithelial fold
0.50	GO:0030539	male genitalia development
0.49	GO:0042733	embryonic digit morphogenesis

0.65	GO:0043565	sequence-specific DNA binding
0.49	GO:0035326	enhancer binding
0.49	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.47	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003682	chromatin binding
0.45	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q90473|HSP7C_DANRE
Heat shock cognate 71 kDa protein
Search

0.63	Heat shock cognate protein isoform A

0.52	GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy
0.51	GO:0061738	late endosomal microautophagy
0.51	GO:0072318	clathrin coat disassembly
0.51	GO:0044829	positive regulation by host of viral genome replication
0.50	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.48	GO:0051085	chaperone cofactor-dependent protein refolding
0.47	GO:1902904	negative regulation of supramolecular fiber organization
0.47	GO:0031647	regulation of protein stability
0.46	GO:0042026	protein refolding
0.45	GO:0045892	negative regulation of transcription, DNA-templated

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0055131	C3HC4-type RING finger domain binding
0.49	GO:0001786	phosphatidylserine binding
0.48	GO:0045296	cadherin binding
0.47	GO:0031072	heat shock protein binding
0.47	GO:0001664	G-protein coupled receptor binding
0.47	GO:0031625	ubiquitin protein ligase binding

0.50	GO:0000974	Prp19 complex
0.48	GO:0043209	myelin sheath
0.47	GO:0070062	extracellular exosome
0.47	GO:0005770	late endosome
0.46	GO:0000151	ubiquitin ligase complex
0.43	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.42	GO:0042470	melanosome
0.42	GO:0030529	intracellular ribonucleoprotein complex
0.38	GO:0043202	lysosomal lumen

sp|Q90474|H90A1_DANRE
Heat shock protein HSP 90-alpha 1
Search

0.70	Epididymis luminal secretory protein 52

0.69	GO:0006457	protein folding
0.65	GO:0009409	response to cold
0.61	GO:0009408	response to heat
0.60	GO:0046677	response to antibiotic
0.51	GO:1905323	telomerase holoenzyme complex assembly
0.49	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.49	GO:0051973	positive regulation of telomerase activity
0.49	GO:0007004	telomere maintenance via telomerase
0.48	GO:0045040	protein import into mitochondrial outer membrane
0.47	GO:0051131	chaperone-mediated protein complex assembly

0.71	GO:0051082	unfolded protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0030235	nitric-oxide synthase regulator activity
0.52	GO:0030911	TPR domain binding
0.49	GO:0070182	DNA polymerase binding
0.49	GO:0097110	scaffold protein binding
0.49	GO:0097718	disordered domain specific binding

0.52	GO:0005634	nucleus
0.47	GO:0032587	ruffle membrane
0.46	GO:0043209	myelin sheath
0.44	GO:0005737	cytoplasm
0.40	GO:0099512	supramolecular fiber
0.40	GO:0097708	intracellular vesicle
0.40	GO:0043234	protein complex
0.39	GO:0097226	sperm mitochondrial sheath
0.38	GO:0097524	sperm plasma membrane
0.38	GO:0043025	neuronal cell body

0.41

GO:0016887

sp|Q90476|LHX1_DANRE
LIM/homeobox protein Lhx1
Search

LHX1

0.92	LIM homeobox protein 1

0.67	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation
0.66	GO:0021527	spinal cord association neuron differentiation
0.65	GO:0021702	cerebellar Purkinje cell differentiation
0.61	GO:0030900	forebrain development
0.60	GO:2000744	positive regulation of anterior head development
0.60	GO:0097477	lateral motor column neuron migration
0.60	GO:2000768	positive regulation of nephron tubule epithelial cell differentiation
0.60	GO:0061205	paramesonephric duct development
0.59	GO:0072049	comma-shaped body morphogenesis
0.59	GO:0035847	uterine epithelium development

0.64	GO:0043565	sequence-specific DNA binding
0.53	GO:0046872	metal ion binding
0.45	GO:0003700	DNA binding transcription factor activity
0.44	GO:0003714	transcription corepressor activity
0.35	GO:0035326	enhancer binding
0.35	GO:0005515	protein binding
0.34	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.44	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q90477|MYOD1_DANRE
Myoblast determination protein 1 homolog
Search

MYOD1

0.91	Myogenic factor

0.79	GO:0007517	muscle organ development
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.53	GO:0043503	skeletal muscle fiber adaptation
0.53	GO:0014904	myotube cell development
0.53	GO:0007518	myoblast fate determination
0.52	GO:0014908	myotube differentiation involved in skeletal muscle regeneration
0.52	GO:0048747	muscle fiber development
0.52	GO:1901741	positive regulation of myoblast fusion

0.67	GO:0046983	protein dimerization activity
0.54	GO:0003677	DNA binding
0.49	GO:0035257	nuclear hormone receptor binding
0.49	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.47	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0003713	transcription coactivator activity
0.47	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0003682	chromatin binding
0.41	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.34	GO:0005249	voltage-gated potassium channel activity

0.60	GO:0005634	nucleus
0.48	GO:0030016	myofibril
0.46	GO:0005667	transcription factor complex
0.45	GO:0000785	chromatin
0.44	GO:0005829	cytosol
0.43	GO:0070013	intracellular organelle lumen
0.34	GO:0008076	voltage-gated potassium channel complex

sp|Q90478|L1CA1_DANRE
Neural cell adhesion molecule L1.1 (Fragment)
Search

0.87	Neuronal cell adhesion molecule

0.49	GO:0061564	axon development
0.49	GO:0007160	cell-matrix adhesion
0.48	GO:0050808	synapse organization
0.48	GO:0097485	neuron projection guidance
0.48	GO:0048667	cell morphogenesis involved in neuron differentiation
0.47	GO:0016477	cell migration
0.42	GO:0045773	positive regulation of axon extension
0.38	GO:0060536	cartilage morphogenesis
0.38	GO:0031102	neuron projection regeneration
0.38	GO:0048678	response to axon injury

0.47	GO:0019904	protein domain specific binding
0.37	GO:0033691	sialic acid binding
0.36	GO:0043621	protein self-association
0.36	GO:0005178	integrin binding
0.35	GO:0042802	identical protein binding

0.50	GO:0030424	axon
0.48	GO:0043025	neuronal cell body
0.46	GO:0009986	cell surface
0.46	GO:0031012	extracellular matrix
0.42	GO:0030426	growth cone
0.40	GO:0005886	plasma membrane
0.36	GO:0043679	axon terminus
0.36	GO:0005925	focal adhesion
0.36	GO:0030425	dendrite
0.35	GO:0098552	side of membrane

sp|Q90479|L1CA2_DANRE
Neural cell adhesion molecule L1.2 (Fragment)
Search

0.91	neural cell adhesion molecule L1-like

0.47	GO:0007411	axon guidance
0.46	GO:0016477	cell migration
0.45	GO:0007160	cell-matrix adhesion
0.45	GO:0050808	synapse organization
0.40	GO:0045773	positive regulation of axon extension
0.40	GO:0035640	exploration behavior
0.39	GO:0008344	adult locomotory behavior
0.39	GO:0043524	negative regulation of neuron apoptotic process
0.39	GO:0050890	cognition
0.36	GO:0033631	cell-cell adhesion mediated by integrin

0.44	GO:0019904	protein domain specific binding
0.39	GO:0002020	protease binding
0.36	GO:0033691	sialic acid binding
0.35	GO:0050839	cell adhesion molecule binding
0.35	GO:0043621	protein self-association
0.34	GO:0032403	protein complex binding
0.34	GO:0042802	identical protein binding
0.34	GO:0005102	receptor binding

0.48	GO:0043005	neuron projection
0.47	GO:0036477	somatodendritic compartment
0.45	GO:0044297	cell body
0.44	GO:0009986	cell surface
0.43	GO:0031012	extracellular matrix
0.42	GO:0120038	plasma membrane bounded cell projection part
0.40	GO:0030427	site of polarized growth
0.39	GO:0005886	plasma membrane
0.39	GO:0045177	apical part of cell
0.35	GO:0005925	focal adhesion

sp|Q90481|NX22A_DANRE
Homeobox protein Nkx-2.2a
Search

NKX2-2

0.93	Homeobox protein Nkx-2.2

0.59	GO:0003327	type B pancreatic cell fate commitment
0.59	GO:0060580	ventral spinal cord interneuron fate determination
0.59	GO:0021530	spinal cord oligodendrocyte cell fate specification
0.58	GO:0003326	pancreatic A cell fate commitment
0.58	GO:0003329	pancreatic PP cell fate commitment
0.57	GO:0048714	positive regulation of oligodendrocyte differentiation
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0003323	type B pancreatic cell development
0.56	GO:0010468	regulation of gene expression

0.64	GO:0043565	sequence-specific DNA binding
0.52	GO:0003713	transcription coactivator activity
0.51	GO:0003682	chromatin binding
0.51	GO:0044212	transcription regulatory region DNA binding
0.49	GO:0008134	transcription factor binding
0.49	GO:0003690	double-stranded DNA binding
0.44	GO:0003700	DNA binding transcription factor activity
0.33	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

EC:3.5.4.4

GO:0004000

sp|Q90482|PO3F1_DANRE
POU domain, class 3, transcription factor 1
Search

0.62	POU domain, class 3, transcription factor 1-B

0.72	GO:0007420	brain development
0.65	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.41	GO:0007422	peripheral nervous system development
0.40	GO:0032292	peripheral nervous system axon ensheathment
0.40	GO:0030216	keratinocyte differentiation
0.40	GO:0021782	glial cell development
0.40	GO:0042552	myelination
0.38	GO:0045893	positive regulation of transcription, DNA-templated

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.40	GO:0001105	RNA polymerase II transcription coactivator activity

0.61	GO:0005634	nucleus
0.38	GO:0005667	transcription factor complex
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q90485|HBB2_DANRE
Hemoglobin subunit beta-2
Search

0.71	Hemoglobin anodic subunit beta

0.79	GO:0015671	oxygen transport
0.36	GO:0030097	hemopoiesis
0.35	GO:0001666	response to hypoxia

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding

0.83

GO:0005833

hemoglobin complex

sp|Q90486|HBB1_DANRE
Hemoglobin subunit beta-1
Search

0.71	Hemoglobin anodic subunit beta

0.79	GO:0015671	oxygen transport
0.36	GO:0030097	hemopoiesis
0.35	GO:0001666	response to hypoxia

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding

0.83

GO:0005833

hemoglobin complex

sp|Q90487|HBA_DANRE
Hemoglobin subunit alpha
Search

0.69	Hemoglobin embryonic subunit alpha

0.79	GO:0015671	oxygen transport
0.35	GO:0001666	response to hypoxia
0.34	GO:0030097	hemopoiesis

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding

0.83	GO:0005833	hemoglobin complex
0.30	GO:0031224	intrinsic component of membrane

tr|Q90VV9|Q90VV9_DANRE
Insulin-like growth factor 1
Search

0.89	Insulin growth factor 1

0.75	GO:0010469	regulation of receptor activity
0.45	GO:1990418	response to insulin-like growth factor stimulus
0.44	GO:0046676	negative regulation of insulin secretion
0.43	GO:0090277	positive regulation of peptide hormone secretion
0.42	GO:0045732	positive regulation of protein catabolic process
0.42	GO:0007275	multicellular organism development
0.42	GO:2001234	negative regulation of apoptotic signaling pathway
0.41	GO:1904073	regulation of trophectodermal cell proliferation
0.41	GO:1905460	negative regulation of vascular associated smooth muscle cell apoptotic process
0.41	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development

0.79	GO:0005179	hormone activity
0.78	GO:0008083	growth factor activity
0.48	GO:0005159	insulin-like growth factor receptor binding
0.40	GO:0005158	insulin receptor binding
0.39	GO:0005178	integrin binding

0.73	GO:0005615	extracellular space
0.40	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex
0.40	GO:0036454	growth factor complex
0.33	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

tr|Q90VY7|Q90VY7_DANRE
Homeodomain transcription factor Prep1
Search

PKNOX1

0.96	Homeodomain transcription factor Prep1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0030218	erythrocyte differentiation
0.53	GO:0030217	T cell differentiation
0.52	GO:0001525	angiogenesis
0.52	GO:0043010	camera-type eye development
0.50	GO:0006366	transcription by RNA polymerase II
0.49	GO:0051173	positive regulation of nitrogen compound metabolic process
0.49	GO:0010604	positive regulation of macromolecule metabolic process

0.55	GO:0003677	DNA binding
0.54	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.52	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.49	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.39	GO:0005737	cytoplasm
0.34	GO:0045271	respiratory chain complex I
0.33	GO:1990204	oxidoreductase complex
0.33	GO:0044446	intracellular organelle part
0.33	GO:0043233	organelle lumen
0.33	GO:0031090	organelle membrane
0.33	GO:0031975	envelope
0.30	GO:0016021	integral component of membrane

sp|Q90W33|HIC2_DANRE
Hypermethylated in cancer 2 protein
Search

HIC2

0.96	Hypermethylated in cancer 1 like

0.50	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.47	GO:0000122	negative regulation of transcription by RNA polymerase II
0.36	GO:0006351	transcription, DNA-templated
0.34	GO:0007275	multicellular organism development
0.34	GO:0030178	negative regulation of Wnt signaling pathway
0.33	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator
0.33	GO:0016055	Wnt signaling pathway

0.51	GO:0003676	nucleic acid binding
0.41	GO:0003700	DNA binding transcription factor activity
0.41	GO:0046872	metal ion binding
0.35	GO:0008022	protein C-terminus binding
0.34	GO:0042826	histone deacetylase binding

0.36	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.33	GO:0043233	organelle lumen
0.33	GO:0000785	chromatin

tr|Q90WA5|Q90WA5_DANRE
Protein disulfide isomerase family A, member 6
Search

PDIP5

0.80	Probable protein disulfide-isomerase A6 (inferred by orthology to a C. elegans protein)

0.68	GO:0045454	cell redox homeostasis
0.45	GO:0043277	apoptotic cell clearance
0.43	GO:0034976	response to endoplasmic reticulum stress
0.41	GO:0006457	protein folding
0.34	GO:0055114	oxidation-reduction process

0.63	GO:0016853	isomerase activity
0.38	GO:0015037	peptide disulfide oxidoreductase activity
0.38	GO:0140096	catalytic activity, acting on a protein

0.41	GO:0005783	endoplasmic reticulum
0.38	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.37	GO:0005615	extracellular space
0.36	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.63

GO:0016853

tr|Q90WW1|Q90WW1_DANRE
Nanos 1
Search

0.89	Nanos like protein 3

0.72	GO:0006417	regulation of translation
0.62	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.59	GO:0007276	gamete generation
0.56	GO:0030718	germ-line stem cell population maintenance
0.55	GO:0034249	negative regulation of cellular amide metabolic process
0.55	GO:0022412	cellular process involved in reproduction in multicellular organism
0.54	GO:0003006	developmental process involved in reproduction
0.53	GO:0048468	cell development
0.53	GO:0032269	negative regulation of cellular protein metabolic process
0.52	GO:0051726	regulation of cell cycle

0.63	GO:0008270	zinc ion binding
0.59	GO:0003723	RNA binding
0.37	GO:0005515	protein binding
0.33	GO:0016301	kinase activity

0.59	GO:0036464	cytoplasmic ribonucleoprotein granule
0.57	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0060293	germ plasm
0.47	GO:0005634	nucleus

tr|Q90WX5|Q90WX5_DANRE
Cone transducin alpha subunit
Search

GNAT2

0.95	Guanine nucleotide-binding protein Gt subunit alpha-X

0.82	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.65	GO:0050908	detection of light stimulus involved in visual perception
0.60	GO:0042462	eye photoreceptor cell development
0.59	GO:0060041	retina development in camera-type eye
0.57	GO:0007602	phototransduction
0.55	GO:0050909	sensory perception of taste
0.52	GO:0071257	cellular response to electrical stimulus
0.52	GO:0048593	camera-type eye morphogenesis
0.48	GO:0008283	cell proliferation
0.45	GO:0050907	detection of chemical stimulus involved in sensory perception

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0001664	G-protein coupled receptor binding
0.36	GO:0000035	acyl binding
0.35	GO:0019901	protein kinase binding

0.62	GO:0001917	photoreceptor inner segment
0.61	GO:0001750	photoreceptor outer segment
0.51	GO:0032391	photoreceptor connecting cilium
0.49	GO:1905360	GTPase complex
0.48	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.43	GO:0098797	plasma membrane protein complex
0.39	GO:0098590	plasma membrane region
0.38	GO:0043025	neuronal cell body
0.37	GO:0045177	apical part of cell
0.37	GO:0098588	bounding membrane of organelle

tr|Q90WX6|Q90WX6_DANRE
Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
Search

GNAT1

0.79	Guanine nucleotide-binding protein Gt subunit alpha-X

0.82	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.64	GO:0050917	sensory perception of umami taste
0.57	GO:0009416	response to light stimulus
0.55	GO:0071257	cellular response to electrical stimulus
0.54	GO:0042462	eye photoreceptor cell development
0.54	GO:0050913	sensory perception of bitter taste
0.53	GO:0060041	retina development in camera-type eye
0.53	GO:0050906	detection of stimulus involved in sensory perception
0.52	GO:0050916	sensory perception of sweet taste
0.52	GO:0007601	visual perception

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0001664	G-protein coupled receptor binding
0.37	GO:0000035	acyl binding
0.36	GO:0019901	protein kinase binding

0.58	GO:0001917	photoreceptor inner segment
0.57	GO:0001750	photoreceptor outer segment
0.53	GO:0032391	photoreceptor connecting cilium
0.50	GO:1905360	GTPase complex
0.49	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.45	GO:0043234	protein complex
0.41	GO:0016324	apical plasma membrane
0.39	GO:0030141	secretory granule
0.38	GO:0043025	neuronal cell body
0.38	GO:0097223	sperm part

sp|Q90WY4|ADA2A_DANRE
Alpha-2A adrenergic receptor
Search

0.72	Alpha-2A adrenergic receptor

0.74	GO:0071875	adrenergic receptor signaling pathway
0.53	GO:0006940	regulation of smooth muscle contraction
0.53	GO:0019229	regulation of vasoconstriction
0.53	GO:0030168	platelet activation
0.45	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.44	GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
0.44	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus
0.44	GO:0051044	positive regulation of membrane protein ectodomain proteolysis
0.44	GO:0050995	negative regulation of lipid catabolic process
0.43	GO:0032148	activation of protein kinase B activity

0.74	GO:0004935	adrenergic receptor activity
0.45	GO:0031696	alpha-2C adrenergic receptor binding
0.45	GO:0032795	heterotrimeric G-protein binding
0.44	GO:0051380	norepinephrine binding
0.44	GO:0051379	epinephrine binding
0.44	GO:0031996	thioesterase binding
0.41	GO:0019901	protein kinase binding
0.40	GO:0042803	protein homodimerization activity
0.40	GO:0046982	protein heterodimerization activity
0.39	GO:0031692	alpha-1B adrenergic receptor binding

0.50	GO:0005886	plasma membrane
0.41	GO:0043235	receptor complex
0.34	GO:0005737	cytoplasm
0.34	GO:0045202	synapse
0.30	GO:0016021	integral component of membrane

sp|Q90WY5|ADA2B_DANRE
Alpha-2B adrenergic receptor
Search

ADRA2B

0.79	Adrenoceptor alpha 2B

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:0006940	regulation of smooth muscle contraction
0.35	GO:0019229	regulation of vasoconstriction
0.35	GO:0030168	platelet activation
0.34	GO:0019933	cAMP-mediated signaling
0.34	GO:0007267	cell-cell signaling

0.72

GO:0004930

G-protein coupled receptor activity

0.48	GO:0005886	plasma membrane
0.32	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|Q90WY6|ADA2C_DANRE
Alpha-2C adrenergic receptor
Search

ADRA2C

0.90	Alpha-2 adrenergic receptor

0.85	GO:0071875	adrenergic receptor signaling pathway
0.82	GO:0006940	regulation of smooth muscle contraction
0.81	GO:0019229	regulation of vasoconstriction
0.81	GO:0030168	platelet activation
0.46	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.43	GO:0007267	cell-cell signaling
0.43	GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
0.42	GO:0051930	regulation of sensory perception of pain
0.42	GO:0045932	negative regulation of muscle contraction
0.42	GO:0032148	activation of protein kinase B activity

0.85	GO:0004935	adrenergic receptor activity
0.43	GO:0031694	alpha-2A adrenergic receptor binding
0.43	GO:0051379	epinephrine binding
0.39	GO:0042803	protein homodimerization activity
0.39	GO:0046982	protein heterodimerization activity

0.54	GO:0005886	plasma membrane
0.41	GO:0043679	axon terminus
0.40	GO:0030424	axon
0.36	GO:0005768	endosome
0.30	GO:0016021	integral component of membrane

tr|Q90X37|Q90X37_DANRE
Ier5 protein
Search

IER5

0.87	Immediate early response 5

0.83	GO:1900036	positive regulation of cellular response to heat
0.72	GO:0034605	cellular response to heat
0.68	GO:0042127	regulation of cell proliferation
0.67	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0006351	transcription, DNA-templated

0.66

GO:0042802

identical protein binding

0.72	GO:0000159	protein phosphatase type 2A complex
0.56	GO:0005634	nucleus
0.46	GO:0005737	cytoplasm

sp|Q90X38|GPKOW_DANRE
G patch domain and KOW motifs-containing protein
Search

GPKOW

0.94	G patch domain and KOW motifs

0.48	GO:0000398	mRNA splicing, via spliceosome
0.36	GO:0006412	translation

0.50	GO:0003676	nucleic acid binding
0.37	GO:0003735	structural constituent of ribosome
0.32	GO:0005515	protein binding

0.49	GO:0005681	spliceosomal complex
0.45	GO:0005654	nucleoplasm
0.36	GO:0005840	ribosome

tr|Q90X41|Q90X41_DANRE
Novel protein similar to human splicing factor 3a, subunit 1, 120kD (SF3A1)
Search

SF3A1

0.91	Splicing factor 3 subunit 1

0.63	GO:0006396	RNA processing
0.50	GO:0016071	mRNA metabolic process
0.48	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.45	GO:0022618	ribonucleoprotein complex assembly
0.37	GO:0007283	spermatogenesis

0.59	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.57	GO:0005686	U2 snRNP
0.56	GO:0071013	catalytic step 2 spliceosome
0.56	GO:0005684	U2-type spliceosomal complex
0.54	GO:0016607	nuclear speck
0.48	GO:0071010	prespliceosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q90X44|NRF1_DANRE
Nuclear respiratory factor 1
Search

NRF1

0.97	LOW QUALITY PROTEIN: nuclear respiratory factor 1

0.55	GO:0006366	transcription by RNA polymerase II
0.55	GO:0045944	positive regulation of transcription by RNA polymerase II
0.50	GO:0014823	response to activity
0.50	GO:0045494	photoreceptor cell maintenance
0.49	GO:0003407	neural retina development
0.48	GO:0070417	cellular response to cold
0.38	GO:0007005	mitochondrion organization
0.34	GO:0006091	generation of precursor metabolites and energy

0.80	GO:0001046	core promoter sequence-specific DNA binding
0.72	GO:0042803	protein homodimerization activity
0.59	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.58	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.60	GO:0005634	nucleus
0.52	GO:0005829	cytosol
0.51	GO:0031974	membrane-enclosed lumen
0.46	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.36	GO:0005667	transcription factor complex

sp|Q90X46|GP161_DANRE
G-protein coupled receptor 161
Search

GPR161

0.97	G-protein coupled receptor 161

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.60	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.58	GO:0030819	positive regulation of cAMP biosynthetic process
0.39	GO:0007275	multicellular organism development
0.38	GO:0051924	regulation of calcium ion transport

0.72	GO:0004930	G-protein coupled receptor activity
0.32	GO:0001653	peptide receptor activity

0.56	GO:0055037	recycling endosome
0.53	GO:0005929	cilium
0.41	GO:0031253	cell projection membrane
0.39	GO:0098588	bounding membrane of organelle
0.35	GO:0030139	endocytic vesicle
0.34	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0098805	whole membrane
0.30	GO:0016021	integral component of membrane

tr|Q90X47|Q90X47_DANRE
Coagulation factor V
Search

0.53	Coagulation factor V

0.59	GO:0009617	response to bacterium
0.53	GO:0007596	blood coagulation
0.47	GO:0001775	cell activation
0.42	GO:0008015	blood circulation
0.41	GO:0055114	oxidation-reduction process
0.38	GO:0007155	cell adhesion

0.70	GO:0005507	copper ion binding
0.41	GO:0016491	oxidoreductase activity
0.33	GO:0003676	nucleic acid binding

0.44	GO:0031091	platelet alpha granule
0.41	GO:0005615	extracellular space
0.30	GO:0044425	membrane part

0.41

GO:0016491

sp|Q90X48|S35A5_DANRE
Probable UDP-sugar transporter protein SLC35A5
Search

SLC35A5

0.94	Probable UDP-sugar transporter protein SLC35A5

0.69	GO:0008643	carbohydrate transport
0.63	GO:1902600	hydrogen ion transmembrane transport

0.79

GO:0005351

sugar:proton symporter activity

0.74	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

sp|Q90X49|CCD80_DANRE
Coiled-coil domain-containing protein 80
Search

CCDC80

0.88	Coiled-coil domain-containing protein 80

0.75	GO:0001756	somitogenesis
0.75	GO:0003073	regulation of systemic arterial blood pressure
0.56	GO:0010811	positive regulation of cell-substrate adhesion
0.54	GO:0030198	extracellular matrix organization
0.43	GO:0007411	axon guidance

0.58	GO:0001968	fibronectin binding
0.55	GO:0008201	heparin binding

0.58	GO:0005614	interstitial matrix
0.55	GO:0005604	basement membrane
0.50	GO:0005615	extracellular space
0.32	GO:0036338	viral membrane
0.30	GO:0016020	membrane

sp|Q90XC2|NEK8_DANRE
Serine/threonine-protein kinase Nek8
Search

NEK8

0.95	NIMA (Never in mitosis gene a)-related kinase 8

0.65	GO:0035330	regulation of hippo signaling
0.63	GO:0006468	protein phosphorylation
0.61	GO:0007368	determination of left/right symmetry
0.59	GO:0007507	heart development
0.58	GO:0009887	animal organ morphogenesis

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.67	GO:0097543	ciliary inversin compartment
0.63	GO:0097546	ciliary base
0.30	GO:0031224	intrinsic component of membrane

tr|Q90XD1|Q90XD1_DANRE
HMG-box transcription factor Sox10
Search

SOX10

0.94	Transcription factor SOX-10

0.53	GO:0030318	melanocyte differentiation
0.53	GO:0048709	oligodendrocyte differentiation
0.53	GO:0048484	enteric nervous system development
0.53	GO:0032808	lacrimal gland development
0.53	GO:0001755	neural crest cell migration
0.52	GO:0021782	glial cell development
0.52	GO:0042552	myelination
0.52	GO:0007422	peripheral nervous system development
0.51	GO:0032291	axon ensheathment in central nervous system
0.51	GO:0002052	positive regulation of neuroblast proliferation

0.55	GO:0003677	DNA binding
0.52	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.50	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.48	GO:0003682	chromatin binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.45	GO:0042802	identical protein binding
0.45	GO:0008134	transcription factor binding
0.37	GO:0034236	protein kinase A catalytic subunit binding
0.36	GO:0097157	pre-mRNA intronic binding
0.35	GO:0008013	beta-catenin binding

0.61	GO:0005634	nucleus
0.52	GO:0031315	extrinsic component of mitochondrial outer membrane
0.44	GO:0070013	intracellular organelle lumen
0.36	GO:0000785	chromatin
0.34	GO:0043234	protein complex

tr|Q90XE6|Q90XE6_DANRE
Kruppel-like factor 1 (erythroid)
Search

0.97	zinc finger and BTB domain-containing protein 7B-like

0.51	GO:0030218	erythrocyte differentiation
0.49	GO:0071499	cellular response to laminar fluid shear stress
0.48	GO:0010628	positive regulation of gene expression
0.47	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.47	GO:0060509	Type I pneumocyte differentiation
0.46	GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress
0.46	GO:0009790	embryo development
0.46	GO:0061515	myeloid cell development
0.45	GO:0035264	multicellular organism growth
0.45	GO:0071695	anatomical structure maturation

0.51	GO:0003676	nucleic acid binding
0.44	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding

0.44	GO:0000790	nuclear chromatin
0.36	GO:0005654	nucleoplasm
0.34	GO:0005794	Golgi apparatus

tr|Q90XE7|Q90XE7_DANRE
Klf2b protein
Search

KLF2

0.93	Kruppel like factor 2

0.53	GO:0071499	cellular response to laminar fluid shear stress
0.51	GO:0060509	Type I pneumocyte differentiation
0.51	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.50	GO:0043249	erythrocyte maturation
0.50	GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress
0.48	GO:0035264	multicellular organism growth
0.46	GO:0040029	regulation of gene expression, epigenetic
0.46	GO:0051247	positive regulation of protein metabolic process
0.45	GO:0009653	anatomical structure morphogenesis
0.43	GO:0001701	in utero embryonic development

0.51	GO:0003676	nucleic acid binding
0.46	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding

0.46

GO:0000790

nuclear chromatin

sp|Q90XF2|KPCI_DANRE
Protein kinase C iota type
Search

PRKCI

0.63	Protein kinase C iota type

0.62	GO:0006468	protein phosphorylation
0.61	GO:0035556	intracellular signal transduction
0.60	GO:0007163	establishment or maintenance of cell polarity
0.58	GO:0042461	photoreceptor cell development
0.57	GO:0048592	eye morphogenesis
0.56	GO:0045216	cell-cell junction organization
0.56	GO:0034351	negative regulation of glial cell apoptotic process
0.56	GO:0060252	positive regulation of glial cell proliferation
0.56	GO:2000353	positive regulation of endothelial cell apoptotic process
0.54	GO:0046326	positive regulation of glucose import

0.81	GO:0004697	protein kinase C activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.50	GO:0005543	phospholipid binding
0.37	GO:0019904	protein domain specific binding

0.55	GO:0043220	Schmidt-Lanterman incisure
0.53	GO:0045171	intercellular bridge
0.52	GO:0016324	apical plasma membrane
0.48	GO:0015630	microtubule cytoskeleton
0.47	GO:0005829	cytosol
0.46	GO:0043296	apical junction complex
0.44	GO:0005913	cell-cell adherens junction
0.44	GO:0005634	nucleus
0.40	GO:0031226	intrinsic component of plasma membrane
0.39	GO:0070160	occluding junction

0.81

EC:2.7.11.13

GO:0004697

sp|Q90XG0|TPISB_DANRE
Triosephosphate isomerase B
Search

TPI1

0.47	Triosephosphate isomerase B

0.73	GO:0019319	hexose biosynthetic process
0.72	GO:0006098	pentose-phosphate shunt
0.71	GO:0006006	glucose metabolic process
0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.49	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process
0.44	GO:0046174	polyol catabolic process
0.44	GO:0006071	glycerol metabolic process
0.44	GO:0007275	multicellular organism development

0.78	GO:0004807	triose-phosphate isomerase activity
0.47	GO:0031625	ubiquitin protein ligase binding

0.42	GO:0005829	cytosol
0.34	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.78	EC:5.3.1.1	GO:0004807
0.78	KEGG:R01015	GO:0004807

tr|Q90XH2|Q90XH2_DANRE
Meis homeobox 1 b
Search

MEIS1

0.95	Meis homeobox 1 b

0.67	GO:0060216	definitive hemopoiesis
0.64	GO:0048593	camera-type eye morphogenesis
0.63	GO:0030099	myeloid cell differentiation
0.63	GO:0001501	skeletal system development
0.62	GO:0001525	angiogenesis
0.60	GO:0045638	negative regulation of myeloid cell differentiation
0.58	GO:0002088	lens development in camera-type eye
0.58	GO:0048468	cell development
0.57	GO:0045665	negative regulation of neuron differentiation
0.57	GO:1903506	regulation of nucleic acid-templated transcription

0.58	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.57	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0003682	chromatin binding
0.52	GO:0046982	protein heterodimerization activity
0.38	GO:0003712	transcription cofactor activity
0.37	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.53	GO:0005667	transcription factor complex
0.45	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|Q90XR1|Q90XR1_DANRE
Claudin 12
Search

CLDN12

0.97	Claudin 12 (Predicted)

0.35

GO:0016338

calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules

0.53	GO:0005198	structural molecule activity
0.34	GO:0042802	identical protein binding

0.68	GO:0005923	bicellular tight junction
0.54	GO:0016328	lateral plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q90XR2|Q90XR2_DANRE
Claudin c
Search

0.67

Claudin c

0.48	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.47	GO:0045216	cell-cell junction organization
0.46	GO:0051291	protein heterooligomerization
0.45	GO:0003382	epithelial cell morphogenesis
0.45	GO:0070293	renal absorption
0.45	GO:0034329	cell junction assembly
0.45	GO:0001666	response to hypoxia
0.44	GO:0061436	establishment of skin barrier
0.44	GO:0051260	protein homooligomerization
0.42	GO:1902476	chloride transmembrane transport

0.62	GO:0005198	structural molecule activity
0.43	GO:0042802	identical protein binding
0.42	GO:0005254	chloride channel activity
0.39	GO:0104005	hijacked molecular function
0.33	GO:0004888	transmembrane signaling receptor activity

0.81	GO:0005923	bicellular tight junction
0.56	GO:0005886	plasma membrane
0.37	GO:0045178	basal part of cell
0.37	GO:0045177	apical part of cell
0.36	GO:0034707	chloride channel complex
0.35	GO:0097574	lateral part of cell
0.32	GO:0005737	cytoplasm

tr|Q90XR6|Q90XR6_DANRE
Claudin
Search

0.67

Claudin a

0.40	GO:0048513	animal organ development
0.40	GO:0033561	regulation of water loss via skin
0.39	GO:0070293	renal absorption
0.39	GO:0048882	lateral line development
0.38	GO:0002028	regulation of sodium ion transport
0.38	GO:0070830	bicellular tight junction assembly
0.37	GO:0051291	protein heterooligomerization
0.37	GO:1902476	chloride transmembrane transport
0.37	GO:0001666	response to hypoxia
0.36	GO:0051260	protein homooligomerization

0.62	GO:0005198	structural molecule activity
0.37	GO:0005254	chloride channel activity
0.34	GO:0042802	identical protein binding

0.81	GO:0005923	bicellular tight junction
0.56	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q90XR8|Q90XR8_DANRE
Claudin b
Search

0.65

Claudin b

0.41	GO:0048884	neuromast development
0.41	GO:0002028	regulation of sodium ion transport
0.39	GO:0061436	establishment of skin barrier
0.38	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.38	GO:0070293	renal absorption
0.38	GO:0045216	cell-cell junction organization
0.37	GO:0051291	protein heterooligomerization
0.37	GO:0034329	cell junction assembly
0.37	GO:0001666	response to hypoxia
0.36	GO:1902476	chloride transmembrane transport

0.62	GO:0005198	structural molecule activity
0.36	GO:0005254	chloride channel activity
0.36	GO:0042802	identical protein binding
0.35	GO:0104005	hijacked molecular function

0.81	GO:0005923	bicellular tight junction
0.56	GO:0005886	plasma membrane
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|Q90XR9|Q90XR9_DANRE
Claudin
Search

0.68	Voltage-dependent calcium channel gamma-4 subunit

0.51	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.49	GO:0070293	renal absorption
0.49	GO:0061436	establishment of skin barrier
0.48	GO:0003382	epithelial cell morphogenesis
0.48	GO:0070830	bicellular tight junction assembly
0.48	GO:0051291	protein heterooligomerization
0.47	GO:0001666	response to hypoxia
0.45	GO:0051260	protein homooligomerization
0.45	GO:1902476	chloride transmembrane transport
0.39	GO:0045471	response to ethanol

0.62	GO:0005198	structural molecule activity
0.45	GO:0005254	chloride channel activity
0.45	GO:0042802	identical protein binding
0.35	GO:0001618	virus receptor activity
0.34	GO:0099600	transmembrane receptor activity
0.34	GO:0038023	signaling receptor activity

0.81	GO:0005923	bicellular tight junction
0.56	GO:0016327	apicolateral plasma membrane
0.49	GO:0016328	lateral plasma membrane
0.42	GO:0005887	integral component of plasma membrane
0.37	GO:0034707	chloride channel complex
0.36	GO:0009925	basal plasma membrane
0.35	GO:0016324	apical plasma membrane
0.35	GO:0070062	extracellular exosome
0.33	GO:0005737	cytoplasm
0.32	GO:0043231	intracellular membrane-bounded organelle

tr|Q90Y03|Q90Y03_DANRE
Aldehyde dehydrogenase 1 family, member A2
Search

ALDH1A2

0.71	retinal dehydrogenase 2

0.53	GO:0055114	oxidation-reduction process
0.51	GO:0001523	retinoid metabolic process
0.49	GO:0034754	cellular hormone metabolic process
0.48	GO:0016102	diterpenoid biosynthetic process
0.48	GO:0031076	embryonic camera-type eye development
0.47	GO:0034308	primary alcohol metabolic process
0.47	GO:0035799	ureter maturation
0.46	GO:0016331	morphogenesis of embryonic epithelium
0.46	GO:0032526	response to retinoic acid
0.45	GO:0035115	embryonic forelimb morphogenesis

0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.41	GO:0016918	retinal binding
0.37	GO:0051287	NAD binding
0.37	GO:0005497	androgen binding
0.37	GO:0004745	retinol dehydrogenase activity
0.35	GO:0005096	GTPase activator activity
0.35	GO:0042802	identical protein binding

0.42	GO:0005829	cytosol
0.39	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus

0.69

GO:0016620

sp|Q90Y50|CXAR_DANRE
Coxsackievirus and adenovirus receptor homolog
Search

CXADR

0.97	Coxsackie virus and adenovirus receptor

0.44	GO:0010669	epithelial structure maintenance
0.44	GO:0048739	cardiac muscle fiber development
0.44	GO:0030593	neutrophil chemotaxis
0.44	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.44	GO:0086067	AV node cell to bundle of His cell communication
0.43	GO:0008354	germ cell migration
0.43	GO:0034109	homotypic cell-cell adhesion
0.43	GO:0046629	gamma-delta T cell activation
0.42	GO:0045216	cell-cell junction organization
0.41	GO:0031532	actin cytoskeleton reorganization

0.44	GO:0071253	connexin binding
0.43	GO:0030165	PDZ domain binding
0.43	GO:0008013	beta-catenin binding
0.42	GO:0050839	cell adhesion molecule binding
0.39	GO:0104005	hijacked molecular function
0.39	GO:0086082	cell adhesive protein binding involved in AV node cell-bundle of His cell communication
0.38	GO:0032403	protein complex binding
0.38	GO:0005102	receptor binding
0.37	GO:0042802	identical protein binding

0.44	GO:0016323	basolateral plasma membrane
0.44	GO:0016327	apicolateral plasma membrane
0.44	GO:0005923	bicellular tight junction
0.43	GO:0005912	adherens junction
0.42	GO:0030175	filopodium
0.42	GO:0045121	membrane raft
0.42	GO:0030426	growth cone
0.42	GO:0001669	acrosomal vesicle
0.41	GO:0044297	cell body
0.40	GO:0014704	intercalated disc

sp|Q90Y54|JAG1B_DANRE
Protein jagged-1b
Search

sp|Q90Y57|JAG1A_DANRE
Protein jagged-1a
Search

tr|Q90YC5|Q90YC5_DANRE
Ephrin A3b
Search

0.82	GO:0048013	ephrin receptor signaling pathway
0.48	GO:0007411	axon guidance
0.45	GO:1902961	positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
0.45	GO:0030316	osteoclast differentiation
0.45	GO:0046849	bone remodeling
0.43	GO:0016525	negative regulation of angiogenesis
0.37	GO:0045664	regulation of neuron differentiation
0.37	GO:0021772	olfactory bulb development
0.35	GO:0007267	cell-cell signaling
0.35	GO:0042472	inner ear morphogenesis

0.84	GO:0046875	ephrin receptor binding
0.35	GO:0005005	transmembrane-ephrin receptor activity
0.32	GO:0004222	metalloendopeptidase activity
0.32	GO:0003723	RNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005886	plasma membrane
0.38	GO:0031225	anchored component of membrane
0.37	GO:0043204	perikaryon
0.36	GO:0031594	neuromuscular junction
0.30	GO:0016021	integral component of membrane

0.32

GO:0004222

sp|Q90YJ2|NGB_DANRE
Neuroglobin
Search

NGB

0.96	Neuroglobin

0.79	GO:0015671	oxygen transport
0.45	GO:0001666	response to hypoxia
0.37	GO:0055114	oxidation-reduction process
0.36	GO:0006493	protein O-linked glycosylation
0.36	GO:0097502	mannosylation
0.35	GO:0006915	apoptotic process
0.35	GO:1903206	negative regulation of hydrogen peroxide-induced cell death
0.34	GO:0010039	response to iron ion
0.34	GO:0007568	aging
0.34	GO:0007601	visual perception

0.79	GO:0005344	oxygen carrier activity
0.63	GO:0020037	heme binding
0.57	GO:0019825	oxygen binding
0.54	GO:0046872	metal ion binding
0.44	GO:0098809	nitrite reductase activity
0.36	GO:0000030	mannosyltransferase activity
0.34	GO:0005515	protein binding

0.47	GO:0043204	perikaryon
0.35	GO:0005737	cytoplasm
0.34	GO:0043005	neuron projection
0.34	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.36

GO:0000030

sp|Q90YL3|MED26_DANRE
Mediator of RNA polymerase II transcription subunit 26
Search

0.86	LOW QUALITY PROTEIN: mediator of RNA polymerase II transcription subunit 26

0.40	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0006351	transcription, DNA-templated

0.42	GO:0001104	RNA polymerase II transcription cofactor activity
0.35	GO:0003713	transcription coactivator activity
0.33	GO:0005515	protein binding

0.59	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.44	GO:0043234	protein complex
0.43	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q90YL4|S61A2_DANRE
Protein transport protein Sec61 subunit alpha-like 2
Search

SEC61A1

0.89	transport protein Sec61 subunit alpha

0.65	GO:0015031	protein transport
0.58	GO:0039019	pronephric nephron development
0.51	GO:0007029	endoplasmic reticulum organization
0.51	GO:0072599	establishment of protein localization to endoplasmic reticulum
0.51	GO:0016049	cell growth
0.48	GO:0046907	intracellular transport
0.47	GO:0090150	establishment of protein localization to membrane
0.38	GO:0034341	response to interferon-gamma
0.37	GO:0021986	habenula development
0.35	GO:0036498	IRE1-mediated unfolded protein response

0.47	GO:0043022	ribosome binding
0.34	GO:0005515	protein binding
0.33	GO:0022857	transmembrane transporter activity

0.50	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0005791	rough endoplasmic reticulum
0.35	GO:0030670	phagocytic vesicle membrane
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|Q90YL6|Q90YL6_DANRE
Nr5a2 protein
Search

NR5A2

0.94	Steroidogenic factor 1

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.59	GO:0031016	pancreas development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.56	GO:0030855	epithelial cell differentiation
0.55	GO:0045070	positive regulation of viral genome replication
0.55	GO:0008206	bile acid metabolic process
0.54	GO:0042632	cholesterol homeostasis

0.79	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0035326	enhancer binding
0.52	GO:0003682	chromatin binding
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.50	GO:0005543	phospholipid binding
0.34	GO:0044877	macromolecular complex binding

0.61	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.43	GO:0044446	intracellular organelle part
0.38	GO:0005737	cytoplasm
0.33	GO:0005694	chromosome
0.33	GO:0043233	organelle lumen

tr|Q90YM0|Q90YM0_DANRE
Cell adhesion molecule OCAM
Search

NCAM2

0.95	Cell adhesion molecule OCAM

0.71	GO:0007155	cell adhesion
0.41	GO:0007413	axonal fasciculation
0.40	GO:0001666	response to hypoxia
0.39	GO:0007608	sensory perception of smell

0.48

GO:0042802

identical protein binding

0.49	GO:0016604	nuclear body
0.49	GO:0030424	axon
0.40	GO:0005886	plasma membrane
0.34	GO:0031225	anchored component of membrane
0.30	GO:0016021	integral component of membrane

sp|Q90YM8|CYFP1_DANRE
Cytoplasmic FMR1-interacting protein 1 homolog
Search

CYFIP1

0.93	Cytoplasmic FMR1 interacting protein 1

0.84	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway
0.82	GO:0097484	dendrite extension
0.77	GO:0099563	modification of synaptic structure
0.76	GO:0016601	Rac protein signal transduction
0.75	GO:0007409	axonogenesis
0.74	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation
0.74	GO:0030032	lamellipodium assembly
0.70	GO:0050890	cognition
0.63	GO:0032268	regulation of cellular protein metabolic process
0.61	GO:0034248	regulation of cellular amide metabolic process

0.73	GO:0048365	Rac GTPase binding
0.65	GO:0032403	protein complex binding
0.47	GO:0000340	RNA 7-methylguanosine cap binding
0.41	GO:0003779	actin binding
0.39	GO:0005522	profilin binding

0.74	GO:0031209	SCAR complex
0.73	GO:0048471	perinuclear region of cytoplasm
0.72	GO:0005845	mRNA cap binding complex
0.70	GO:0030027	lamellipodium
0.66	GO:0043005	neuron projection
0.55	GO:0045202	synapse
0.47	GO:0032433	filopodium tip
0.45	GO:0043025	neuronal cell body
0.45	GO:0030054	cell junction
0.45	GO:0030427	site of polarized growth

tr|Q90YX4|Q90YX4_DANRE
Cyclin-dependent kinase inhibitor 1Bb
Search

CDKN1B

0.88	Cyclin-dependent kinase inhibitor 1Bb

0.84	GO:0007050	cell cycle arrest
0.82	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.71	GO:0042127	regulation of cell proliferation
0.58	GO:0007346	regulation of mitotic cell cycle
0.57	GO:1902746	regulation of lens fiber cell differentiation
0.57	GO:1904030	negative regulation of cyclin-dependent protein kinase activity
0.55	GO:0071236	cellular response to antibiotic
0.54	GO:0071285	cellular response to lithium ion
0.54	GO:0048102	autophagic cell death
0.53	GO:0031116	positive regulation of microtubule polymerization

0.85	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.53	GO:0016301	kinase activity
0.52	GO:0030332	cyclin binding
0.52	GO:0019903	protein phosphatase binding
0.50	GO:0019901	protein kinase binding
0.49	GO:0032403	protein complex binding
0.39	GO:0030544	Hsp70 protein binding
0.37	GO:0051087	chaperone binding
0.37	GO:0030295	protein kinase activator activity
0.36	GO:0031625	ubiquitin protein ligase binding

0.61	GO:0005634	nucleus
0.53	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex
0.46	GO:0005737	cytoplasm
0.38	GO:0097708	intracellular vesicle
0.37	GO:0012505	endomembrane system
0.37	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0005576	extracellular region

0.36

GO:0016773

tr|Q90YX8|Q90YX8_DANRE
Iroquois homeobox 7
Search

0.83	Iroquois-class homeodomain protein irx-2

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0048598	embryonic morphogenesis
0.52	GO:0060042	retina morphogenesis in camera-type eye
0.51	GO:0007417	central nervous system development
0.50	GO:0072498	embryonic skeletal joint development
0.49	GO:0048646	anatomical structure formation involved in morphogenesis
0.49	GO:0032330	regulation of chondrocyte differentiation
0.49	GO:0060322	head development

0.65	GO:0043565	sequence-specific DNA binding
0.35	GO:0044212	transcription regulatory region DNA binding
0.34	GO:0004222	metalloendopeptidase activity
0.34	GO:0005509	calcium ion binding
0.33	GO:0008270	zinc ion binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

GO:0004222

tr|Q90YY7|Q90YY7_DANRE
Ceramide synthase 2a
Search

CERS2

0.96	ceramide synthase 2

0.58	GO:0046513	ceramide biosynthetic process
0.40	GO:1900148	negative regulation of Schwann cell migration
0.40	GO:1905045	negative regulation of Schwann cell proliferation involved in axon regeneration

0.59	GO:0050291	sphingosine N-acyltransferase activity
0.53	GO:0003677	DNA binding
0.33	GO:0005515	protein binding

0.58	GO:0005634	nucleus
0.44	GO:0005783	endoplasmic reticulum
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.35	GO:0031967	organelle envelope
0.35	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.59

EC:2.3.1.24

GO:0050291

sp|Q90Z00|FGR1A_DANRE
Fibroblast growth factor receptor 1-A
Search

0.63	Fibroblast growth factor receptor

0.84	GO:0008543	fibroblast growth factor receptor signaling pathway
0.79	GO:0008284	positive regulation of cell proliferation
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.52	GO:2000830	positive regulation of parathyroid hormone secretion
0.52	GO:0021769	orbitofrontal cortex development
0.51	GO:0048378	regulation of lateral mesodermal cell fate specification
0.51	GO:0021847	ventricular zone neuroblast division
0.51	GO:1903465	positive regulation of mitotic cell cycle DNA replication
0.51	GO:1904849	positive regulation of cell chemotaxis to fibroblast growth factor
0.51	GO:0090272	negative regulation of fibroblast growth factor production

0.85	GO:0005007	fibroblast growth factor-activated receptor activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0090722	receptor-receptor interaction
0.50	GO:0017134	fibroblast growth factor binding
0.45	GO:0042803	protein homodimerization activity
0.44	GO:1901681	sulfur compound binding
0.35	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity

0.46	GO:0043235	receptor complex
0.45	GO:0005730	nucleolus
0.39	GO:0005886	plasma membrane
0.36	GO:0031410	cytoplasmic vesicle
0.35	GO:0005829	cytosol
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

sp|Q90Z08|U119B_DANRE
Protein unc-119 homolog B
Search

UNC119B

0.87	Unc-119 lipid binding chaperone B

0.68	GO:0007399	nervous system development
0.63	GO:0060271	cilium assembly
0.62	GO:0042953	lipoprotein transport
0.54	GO:0070121	Kupffer's vesicle development
0.49	GO:0030154	cell differentiation
0.40	GO:0061098	positive regulation of protein tyrosine kinase activity
0.39	GO:0007601	visual perception
0.38	GO:0000281	mitotic cytokinesis
0.36	GO:0016255	attachment of GPI anchor to protein

0.56	GO:0008289	lipid binding
0.36	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding

0.61	GO:0035869	ciliary transition zone
0.38	GO:0045171	intercellular bridge
0.38	GO:0051233	spindle midzone
0.37	GO:0000922	spindle pole
0.37	GO:0005813	centrosome
0.36	GO:0042765	GPI-anchor transamidase complex
0.35	GO:0005829	cytosol

sp|Q90Z10|RL13_DANRE
60S ribosomal protein L13
Search

RPL13

0.68	Ribosomal protein L13

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.41	GO:0051726	regulation of cell cycle
0.35	GO:0097421	liver regeneration
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006508	proteolysis
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.63	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.36	GO:0004222	metalloendopeptidase activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0005515	protein binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.47	GO:0005829	cytosol
0.44	GO:0005730	nucleolus
0.43	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.36

GO:0004222

tr|Q90Z32|Q90Z32_DANRE
Ephrin B2b
Search

0.72	GO:0048013	ephrin receptor signaling pathway
0.52	GO:0016477	cell migration
0.52	GO:0031295	T cell costimulation
0.52	GO:0048699	generation of neurons
0.51	GO:0009653	anatomical structure morphogenesis
0.50	GO:0009888	tissue development
0.50	GO:0048513	animal organ development
0.50	GO:0001568	blood vessel development
0.50	GO:0120036	plasma membrane bounded cell projection organization
0.49	GO:0008284	positive regulation of cell proliferation

0.74	GO:0046875	ephrin receptor binding
0.35	GO:0001618	virus receptor activity
0.33	GO:0016301	kinase activity
0.33	GO:0003777	microtubule motor activity
0.32	GO:0016887	ATPase activity
0.32	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008144	drug binding

0.43	GO:0098857	membrane microdomain
0.42	GO:0005886	plasma membrane
0.38	GO:0005634	nucleus
0.36	GO:0005925	focal adhesion
0.35	GO:0070062	extracellular exosome
0.35	GO:0005737	cytoplasm
0.35	GO:0045202	synapse
0.30	GO:0016021	integral component of membrane

0.32

GO:0016887

tr|Q90Z33|Q90Z33_DANRE
Ephrin B1
Search

0.73	GO:0048013	ephrin receptor signaling pathway
0.59	GO:0031295	T cell costimulation
0.57	GO:0001667	ameboidal-type cell migration
0.55	GO:0048699	generation of neurons
0.55	GO:0008284	positive regulation of cell proliferation
0.55	GO:0009653	anatomical structure morphogenesis
0.55	GO:0009888	tissue development
0.54	GO:0048513	animal organ development
0.52	GO:0120036	plasma membrane bounded cell projection organization
0.52	GO:0048468	cell development

0.75	GO:0046875	ephrin receptor binding
0.34	GO:0016301	kinase activity

0.49	GO:0045121	membrane raft
0.45	GO:0005886	plasma membrane
0.42	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0045202	synapse
0.34	GO:0005925	focal adhesion
0.30	GO:0031224	intrinsic component of membrane

tr|Q90Z34|Q90Z34_DANRE
Sodium/potassium-transporting ATPase subunit beta
Search

0.81	Sodium/potassium-transporting ATPase subunit beta

0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.49	GO:1903288	positive regulation of potassium ion import
0.49	GO:1903275	positive regulation of sodium ion export
0.49	GO:1903276	regulation of sodium ion export across plasma membrane
0.48	GO:0006883	cellular sodium ion homeostasis
0.48	GO:0086009	membrane repolarization
0.48	GO:1903281	positive regulation of calcium:sodium antiporter activity
0.47	GO:1901018	positive regulation of potassium ion transmembrane transporter activity
0.47	GO:0055119	relaxation of cardiac muscle

0.47	GO:0051117	ATPase binding
0.47	GO:0005391	sodium:potassium-exchanging ATPase activity
0.45	GO:0001671	ATPase activator activity
0.45	GO:0008022	protein C-terminus binding
0.44	GO:0031402	sodium ion binding
0.43	GO:0019901	protein kinase binding
0.43	GO:0030955	potassium ion binding
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.85	GO:0005890	sodium:potassium-exchanging ATPase complex
0.46	GO:0014704	intercalated disc
0.45	GO:0042383	sarcolemma
0.45	GO:0016324	apical plasma membrane
0.44	GO:0043209	myelin sheath
0.44	GO:0016323	basolateral plasma membrane
0.38	GO:0005901	caveola
0.35	GO:0005622	intracellular
0.35	GO:0070062	extracellular exosome
0.33	GO:0012505	endomembrane system

0.47

GO:0005391

tr|Q90Z38|Q90Z38_DANRE
RAN-binding protein 1
Search

RANBP1

0.90	Ran-binding protein 1

0.69	GO:0046907	intracellular transport
0.57	GO:0046604	positive regulation of mitotic centrosome separation
0.52	GO:0007051	spindle organization
0.48	GO:0000082	G1/S transition of mitotic cell cycle
0.48	GO:0006606	protein import into nucleus
0.46	GO:0043547	positive regulation of GTPase activity
0.46	GO:0006405	RNA export from nucleus
0.45	GO:0006511	ubiquitin-dependent protein catabolic process
0.39	GO:0072750	cellular response to leptomycin B
0.37	GO:0051592	response to calcium ion

0.47	GO:0008536	Ran GTPase binding
0.46	GO:0005096	GTPase activator activity
0.37	GO:0005092	GDP-dissociation inhibitor activity
0.37	GO:0045296	cadherin binding

0.51	GO:0005813	centrosome
0.44	GO:0005829	cytosol
0.41	GO:0005634	nucleus
0.38	GO:1904115	axon cytoplasm
0.33	GO:0012505	endomembrane system
0.33	GO:0031967	organelle envelope
0.30	GO:0031224	intrinsic component of membrane

tr|Q90Z40|Q90Z40_DANRE
Guanine nucleotide-binding protein subunit gamma
Search

GNG3

0.71	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.43	GO:0008283	cell proliferation
0.41	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.41	GO:0002040	sprouting angiogenesis
0.38	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.37	GO:0071377	cellular response to glucagon stimulus
0.36	GO:0071380	cellular response to prostaglandin E stimulus
0.36	GO:0071870	cellular response to catecholamine stimulus
0.36	GO:0019933	cAMP-mediated signaling
0.35	GO:0007223	Wnt signaling pathway, calcium modulating pathway

0.64	GO:0004871	signal transducer activity
0.50	GO:0031681	G-protein beta-subunit binding
0.40	GO:0031702	type 1 angiotensin receptor binding
0.36	GO:0003924	GTPase activity

0.81	GO:1905360	GTPase complex
0.80	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.65	GO:0098797	plasma membrane protein complex
0.52	GO:0014069	postsynaptic density
0.51	GO:0030425	dendrite
0.51	GO:0044297	cell body
0.38	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

tr|Q90Z68|Q90Z68_DANRE
Iroquois 3 homeobox protein
Search

0.93	Iroquois-class homeodomain protein irx-3

0.58	GO:0048598	embryonic morphogenesis
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0048513	animal organ development
0.53	GO:0035270	endocrine system development
0.51	GO:0072048	renal system pattern specification
0.50	GO:0007379	segment specification
0.50	GO:0009954	proximal/distal pattern formation
0.49	GO:0061333	renal tubule morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.35	GO:0004969	histamine receptor activity
0.35	GO:0003723	RNA binding
0.34	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.33	GO:0044212	transcription regulatory region DNA binding

0.61	GO:0005634	nucleus
0.43	GO:0030424	axon
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q90Z77|Q90Z77_DANRE
HIV-1 Tat interactive protein 2
Search

HTATIP2

0.90	HIV-1 Tat interactive protein 2

0.58	GO:0045765	regulation of angiogenesis
0.54	GO:0051170	nuclear import
0.47	GO:0055114	oxidation-reduction process
0.42	GO:0001525	angiogenesis
0.41	GO:0006915	apoptotic process
0.40	GO:0030154	cell differentiation
0.37	GO:0008213	protein alkylation
0.37	GO:0043067	regulation of programmed cell death
0.36	GO:0043414	macromolecule methylation
0.35	GO:0046777	protein autophosphorylation

0.58	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.57	GO:0051287	NAD binding
0.35	GO:0008168	methyltransferase activity
0.35	GO:0003713	transcription coactivator activity
0.35	GO:0016301	kinase activity
0.34	GO:0005515	protein binding
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0003676	nucleic acid binding

0.56	GO:0005635	nuclear envelope
0.51	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.58

GO:0016620

tr|Q90Z92|Q90Z92_DANRE
Novel immune-type receptor 2b
Search

0.97	Novel immune-type receptor 1m allele 5

0.30

GO:0044425

membrane part

tr|Q90Z98|Q90Z98_DANRE
Bcl-XL-like protein 1
Search

0.97	Anti-apoptotic regulator Bcl-xL

0.74	GO:0042981	regulation of apoptotic process
0.72	GO:0006915	apoptotic process
0.58	GO:0060154	cellular process regulating host cell cycle in response to virus
0.57	GO:0038034	signal transduction in absence of ligand
0.57	GO:0046898	response to cycloheximide
0.56	GO:0052490	negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction
0.56	GO:1903077	negative regulation of protein localization to plasma membrane
0.56	GO:0071312	cellular response to alkaloid
0.55	GO:0071480	cellular response to gamma radiation
0.55	GO:0046902	regulation of mitochondrial membrane permeability

0.58	GO:0051434	BH3 domain binding
0.51	GO:0019901	protein kinase binding
0.51	GO:0042802	identical protein binding
0.51	GO:0046982	protein heterodimerization activity
0.42	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.35	GO:0097371	MDM2/MDM4 family protein binding
0.35	GO:0008134	transcription factor binding
0.34	GO:0030276	clathrin binding
0.34	GO:0032403	protein complex binding
0.34	GO:0051721	protein phosphatase 2A binding

0.57	GO:0097136	Bcl-2 family protein complex
0.52	GO:0005741	mitochondrial outer membrane
0.52	GO:0005813	centrosome
0.48	GO:0005783	endoplasmic reticulum
0.47	GO:0005829	cytosol
0.40	GO:0030672	synaptic vesicle membrane
0.40	GO:0031965	nuclear membrane
0.38	GO:0005759	mitochondrial matrix
0.38	GO:0030054	cell junction
0.35	GO:0005743	mitochondrial inner membrane

tr|Q90ZB2|Q90ZB2_DANRE
Gastrulation brain homeobox 1
Search

0.96	Gastrulation brain homeo box 2

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.53	GO:0021555	midbrain-hindbrain boundary morphogenesis
0.53	GO:0021549	cerebellum development
0.51	GO:0021568	rhombomere 2 development
0.50	GO:0021953	central nervous system neuron differentiation
0.49	GO:0007411	axon guidance
0.49	GO:0021930	cerebellar granule cell precursor proliferation
0.49	GO:0021794	thalamus development

0.63	GO:0043565	sequence-specific DNA binding
0.47	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.46	GO:0001047	core promoter binding
0.46	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.43	GO:0003690	double-stranded DNA binding

0.60

GO:0005634

nucleus

sp|Q90ZE2|ZN703_DANRE
Zinc finger protein 703
Search

ZNF703

0.93	Zinc finger domain-containing protein (Fragment)

0.52	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
0.52	GO:0033601	positive regulation of mammary gland epithelial cell proliferation
0.52	GO:0048513	animal organ development
0.52	GO:0034111	negative regulation of homotypic cell-cell adhesion
0.52	GO:0045892	negative regulation of transcription, DNA-templated
0.51	GO:0071392	cellular response to estradiol stimulus
0.51	GO:0031065	positive regulation of histone deacetylation
0.50	GO:0034333	adherens junction assembly
0.49	GO:0060828	regulation of canonical Wnt signaling pathway
0.49	GO:0007368	determination of left/right symmetry

0.51	GO:0003676	nucleic acid binding
0.47	GO:0070491	repressing transcription factor binding
0.36	GO:0046872	metal ion binding

0.52	GO:0016363	nuclear matrix
0.41	GO:0043234	protein complex
0.38	GO:0005737	cytoplasm

tr|Q90ZE3|Q90ZE3_DANRE
Homeobox transcription factor Meis3
Search

MEIS3

0.89	Myeloid ecotropic viral integration site 3

0.65	GO:1901166	neural crest cell migration involved in autonomic nervous system development
0.63	GO:0031017	exocrine pancreas development
0.62	GO:0048484	enteric nervous system development
0.62	GO:0035066	positive regulation of histone acetylation
0.59	GO:0030902	hindbrain development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:1902680	positive regulation of RNA biosynthetic process

0.55

GO:0003677

DNA binding

0.61	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm

sp|Q90ZE4|PSN2_DANRE
Presenilin-2
Search

PSEN2

0.80	Presenilin

0.81	GO:0007219	Notch signaling pathway
0.76	GO:0042987	amyloid precursor protein catabolic process
0.75	GO:0016485	protein processing
0.56	GO:0006509	membrane protein ectodomain proteolysis
0.54	GO:0035556	intracellular signal transduction
0.52	GO:0050435	amyloid-beta metabolic process
0.48	GO:0007220	Notch receptor processing
0.48	GO:0043085	positive regulation of catalytic activity
0.45	GO:0043066	negative regulation of apoptotic process
0.45	GO:0061053	somite development

0.73	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving
0.34	GO:0005515	protein binding
0.33	GO:0008324	cation transmembrane transporter activity

0.73	GO:0000139	Golgi membrane
0.71	GO:0005789	endoplasmic reticulum membrane
0.52	GO:0005637	nuclear inner membrane
0.50	GO:0000776	kinetochore
0.50	GO:0005813	centrosome
0.48	GO:0035253	ciliary rootlet
0.48	GO:0043198	dendritic shaft
0.47	GO:0031594	neuromuscular junction
0.47	GO:0005887	integral component of plasma membrane
0.47	GO:0030426	growth cone

0.73

EC:3.4.23

GO:0042500

sp|Q90ZL1|MSGN1_DANRE
Mesogenin-1
Search

MSGN1

0.83	Mesogenin-1

0.61	GO:0001756	somitogenesis
0.58	GO:0007498	mesoderm development
0.58	GO:0006366	transcription by RNA polymerase II
0.57	GO:0007369	gastrulation
0.56	GO:0007379	segment specification
0.56	GO:0045944	positive regulation of transcription by RNA polymerase II
0.55	GO:0048729	tissue morphogenesis
0.55	GO:0009880	embryonic pattern specification
0.51	GO:0009887	animal organ morphogenesis
0.48	GO:0060485	mesenchyme development

0.68	GO:0046983	protein dimerization activity
0.59	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.53	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0003682	chromatin binding
0.43	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.42	GO:0035326	enhancer binding
0.34	GO:0004518	nuclease activity

0.45	GO:0005634	nucleus
0.35	GO:0070062	extracellular exosome

0.34

EC:3.1

GO:0004518

sp|Q90ZL2|LANC1_DANRE
LanC-like protein 1
Search

LANCL1

0.96	LanC lantibiotic synthetase component C-like 1 (Bacterial)

0.50	GO:0007165	signal transduction
0.34	GO:0055114	oxidation-reduction process

0.82	GO:0050750	low-density lipoprotein particle receptor binding
0.82	GO:0043295	glutathione binding
0.75	GO:0017124	SH3 domain binding
0.60	GO:0008270	zinc ion binding
0.37	GO:0004930	G-protein coupled receptor activity
0.37	GO:0003995	acyl-CoA dehydrogenase activity
0.36	GO:0005509	calcium ion binding
0.35	GO:0050660	flavin adenine dinucleotide binding

0.47	GO:0005886	plasma membrane
0.42	GO:0070062	extracellular exosome
0.37	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.37

EC:1.3.99.3

GO:0003995

sp|Q90ZM2|S61A1_DANRE
Protein transport protein Sec61 subunit alpha-like 1
Search

SEC61A1

0.89	transport protein Sec61 subunit alpha

0.65	GO:0015031	protein transport
0.58	GO:0039019	pronephric nephron development
0.51	GO:0007029	endoplasmic reticulum organization
0.51	GO:0072599	establishment of protein localization to endoplasmic reticulum
0.50	GO:0016049	cell growth
0.48	GO:0046907	intracellular transport
0.47	GO:0090150	establishment of protein localization to membrane
0.38	GO:0034341	response to interferon-gamma
0.37	GO:0021986	habenula development
0.35	GO:0036498	IRE1-mediated unfolded protein response

0.47	GO:0043022	ribosome binding
0.34	GO:0005515	protein binding
0.33	GO:0022857	transmembrane transporter activity

0.50	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0005791	rough endoplasmic reticulum
0.35	GO:0030670	phagocytic vesicle membrane
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q90ZY4|SBK1_DANRE
Serine/threonine-protein kinase SBK1
Search

0.96	Serine/threonine-protein kinase SBK1

0.63	GO:0006468	protein phosphorylation
0.47	GO:0018210	peptidyl-threonine modification
0.47	GO:0018209	peptidyl-serine modification
0.34	GO:0007420	brain development
0.34	GO:0007266	Rho protein signal transduction
0.34	GO:0031098	stress-activated protein kinase signaling cascade
0.33	GO:0032147	activation of protein kinase activity
0.33	GO:0043408	regulation of MAPK cascade
0.33	GO:0016477	cell migration
0.33	GO:0007346	regulation of mitotic cell cycle

0.67	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0048365	Rac GTPase binding

0.45	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.67

GO:0004674

sp|Q90ZY6|TLK1B_DANRE
Serine/threonine-protein kinase tousled-like 1-B
Search

TLK1

0.80	Serine/threonine-protein kinase tousled-like 1-like

0.63	GO:0006468	protein phosphorylation
0.41	GO:0001672	regulation of chromatin assembly or disassembly
0.37	GO:0006886	intracellular protein transport
0.37	GO:0016569	covalent chromatin modification
0.36	GO:0035556	intracellular signal transduction
0.36	GO:0007049	cell cycle
0.35	GO:0006974	cellular response to DNA damage stimulus

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.37

GO:0005634

nucleus

tr|Q90ZY9|Q90ZY9_DANRE
Syndecan
Search

SDC2

0.82

Syndecan

0.51	GO:0048814	regulation of dendrite morphogenesis
0.49	GO:0016477	cell migration
0.48	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.48	GO:0070121	Kupffer's vesicle development
0.47	GO:0002040	sprouting angiogenesis
0.46	GO:0048565	digestive tract development
0.45	GO:0048813	dendrite morphogenesis
0.45	GO:0007507	heart development
0.43	GO:0097435	supramolecular fiber organization
0.35	GO:0042060	wound healing

0.53	GO:0030165	PDZ domain binding
0.48	GO:0042802	identical protein binding
0.34	GO:0070053	thrombospondin receptor activity

0.48	GO:0031012	extracellular matrix
0.43	GO:0009986	cell surface
0.36	GO:0005796	Golgi lumen
0.35	GO:0043202	lysosomal lumen
0.34	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0043025	neuronal cell body
0.34	GO:0045202	synapse
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q90ZZ7|Q90ZZ7_DANRE
Aldehyde dehydrogenase
Search

ALDH3B1

0.42	Aldehyde dehydrogenase

0.68	GO:0006081	cellular aldehyde metabolic process
0.52	GO:0055114	oxidation-reduction process
0.40	GO:0034599	cellular response to oxidative stress
0.37	GO:0044248	cellular catabolic process
0.37	GO:1901575	organic substance catabolic process
0.36	GO:0006067	ethanol metabolic process
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0030148	sphingolipid biosynthetic process
0.34	GO:0044282	small molecule catabolic process

0.79	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity
0.41	GO:0004029	aldehyde dehydrogenase (NAD) activity
0.35	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity
0.33	GO:0005515	protein binding

0.39	GO:0005829	cytosol
0.36	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0035579	specific granule membrane
0.30	GO:0016021	integral component of membrane

0.79

EC:1.2.1.5

GO:0004030

tr|Q90ZZ8|Q90ZZ8_DANRE
Aldehyde dehydrogenase
Search

0.44	Fatty aldehyde dehydrogenase

0.67	GO:0006081	cellular aldehyde metabolic process
0.52	GO:0055114	oxidation-reduction process
0.50	GO:0033306	phytol metabolic process
0.47	GO:0007422	peripheral nervous system development
0.46	GO:0008544	epidermis development
0.45	GO:0007417	central nervous system development
0.37	GO:0006714	sesquiterpenoid metabolic process
0.34	GO:0030148	sphingolipid biosynthetic process
0.34	GO:0009062	fatty acid catabolic process
0.34	GO:0000302	response to reactive oxygen species

0.77	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity
0.48	GO:0046577	long-chain-alcohol oxidase activity
0.47	GO:0004029	aldehyde dehydrogenase (NAD) activity
0.37	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity
0.36	GO:0008106	alcohol dehydrogenase (NADP+) activity

0.42	GO:0005783	endoplasmic reticulum
0.38	GO:0031090	organelle membrane
0.38	GO:0044429	mitochondrial part
0.38	GO:0031967	organelle envelope
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0042579	microbody
0.36	GO:0031984	organelle subcompartment
0.36	GO:0070062	extracellular exosome
0.35	GO:0005829	cytosol
0.35	GO:0098805	whole membrane

0.77

EC:1.2.1.5

GO:0004030

sp|Q91392|RARGA_DANRE
Retinoic acid receptor gamma-A
Search

0.86	Peroxisome proliferator-activated receptor gamma

0.85	GO:0048384	retinoic acid receptor signaling pathway
0.79	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0003430	growth plate cartilage chondrocyte growth
0.53	GO:0070384	Harderian gland development
0.53	GO:0060534	trachea cartilage development
0.52	GO:0003406	retinal pigment epithelium development

0.86	GO:0003708	retinoic acid receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.52	GO:0046965	retinoid X receptor binding
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003690	double-stranded DNA binding
0.36	GO:0005503	all-trans retinal binding
0.35	GO:0019841	retinol binding
0.35	GO:0001972	retinoic acid binding

0.61	GO:0005634	nucleus
0.46	GO:0005667	transcription factor complex
0.45	GO:0000785	chromatin
0.44	GO:0070013	intracellular organelle lumen
0.34	GO:0008305	integrin complex
0.34	GO:0005829	cytosol

sp|Q91398|CSK2B_DANRE
Casein kinase II subunit beta
Search

CSNK2B

0.59	Casein kinase II subunit beta

0.76	GO:0045859	regulation of protein kinase activity
0.53	GO:0033211	adiponectin-activated signaling pathway
0.53	GO:0032927	positive regulation of activin receptor signaling pathway
0.53	GO:0061154	endothelial tube morphogenesis
0.52	GO:0043537	negative regulation of blood vessel endothelial cell migration
0.52	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.51	GO:0018107	peptidyl-threonine phosphorylation
0.41	GO:0016055	Wnt signaling pathway
0.38	GO:0097421	liver regeneration
0.38	GO:0033574	response to testosterone

0.79	GO:0019887	protein kinase regulator activity
0.52	GO:0016301	kinase activity
0.48	GO:0003682	chromatin binding
0.48	GO:0019904	protein domain specific binding
0.47	GO:0042802	identical protein binding
0.46	GO:0008134	transcription factor binding
0.46	GO:0005102	receptor binding
0.42	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.41	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0043021	ribonucleoprotein complex binding

0.83	GO:0005956	protein kinase CK2 complex
0.51	GO:0031519	PcG protein complex
0.40	GO:0005886	plasma membrane
0.37	GO:0016363	nuclear matrix
0.37	GO:0005737	cytoplasm
0.36	GO:0005929	cilium
0.36	GO:0000785	chromatin
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0097708	intracellular vesicle

0.42

GO:0016773

sp|Q91428|GATA3_DANRE
Transcription factor GATA-3
Search

GATA3

0.96	Trans-acting T-cell-specific transcription factor GATA-3

0.84	GO:0045582	positive regulation of T cell differentiation
0.60	GO:2000611	positive regulation of thyroid hormone generation
0.59	GO:2000667	positive regulation of interleukin-13 secretion
0.59	GO:2000683	regulation of cellular response to X-ray
0.59	GO:2000664	positive regulation of interleukin-5 secretion
0.58	GO:0033600	negative regulation of mammary gland epithelial cell proliferation
0.58	GO:0060231	mesenchymal to epithelial transition
0.57	GO:0035457	cellular response to interferon-alpha
0.57	GO:2000702	regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
0.57	GO:2000734	negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation

0.76	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.57	GO:0071837	HMG box domain binding
0.54	GO:0005134	interleukin-2 receptor binding
0.54	GO:0001047	core promoter binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0003713	transcription coactivator activity
0.52	GO:0035326	enhancer binding
0.51	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.49	GO:0000785	chromatin
0.47	GO:0070013	intracellular organelle lumen
0.45	GO:0005667	transcription factor complex
0.30	GO:0016021	integral component of membrane

sp|Q91981|OTX2_DANRE
Homeobox protein OTX2
Search

OTX2

0.89	Orthodenticle homeobox 2

0.70	GO:0007275	multicellular organism development
0.62	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.61	GO:0000904	cell morphogenesis involved in differentiation
0.60	GO:0120036	plasma membrane bounded cell projection organization
0.60	GO:0006366	transcription by RNA polymerase II
0.59	GO:0045944	positive regulation of transcription by RNA polymerase II
0.57	GO:0006935	chemotaxis
0.56	GO:0006928	movement of cell or subcellular component
0.55	GO:0006461	protein complex assembly
0.45	GO:2000543	positive regulation of gastrulation

0.64	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0001012	RNA polymerase II regulatory region DNA binding
0.57	GO:0003690	double-stranded DNA binding
0.35	GO:0005515	protein binding

0.65	GO:0030426	growth cone
0.61	GO:0005634	nucleus
0.49	GO:0043234	protein complex

sp|Q91994|OTX1B_DANRE
Homeobox protein OTX1 B
Search

OTX1

0.94	Orthodenticle homeobox 1

0.70	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0060322	head development
0.48	GO:0006366	transcription by RNA polymerase II
0.48	GO:0009653	anatomical structure morphogenesis
0.47	GO:1902680	positive regulation of RNA biosynthetic process
0.38	GO:0060429	epithelium development

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.48	GO:0001067	regulatory region nucleic acid binding

0.61

GO:0005634

nucleus

sp|Q92005|EF1A_DANRE
Elongation factor 1-alpha
Search

0.45	Translation elongation factor EF-1 subunit alpha

0.70	GO:0006414	translational elongation
0.44	GO:0071364	cellular response to epidermal growth factor stimulus
0.35	GO:0090218	positive regulation of lipid kinase activity
0.34	GO:0043065	positive regulation of apoptotic process

0.71	GO:0003746	translation elongation factor activity
0.66	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0019901	protein kinase binding
0.39	GO:0005516	calmodulin binding
0.39	GO:0000049	tRNA binding

0.47	GO:0005737	cytoplasm
0.42	GO:0032587	ruffle membrane
0.41	GO:0043209	myelin sheath
0.40	GO:0005730	nucleolus
0.40	GO:0015629	actin cytoskeleton
0.39	GO:0044430	cytoskeletal part
0.36	GO:0070062	extracellular exosome
0.33	GO:0043234	protein complex

sp|Q92008|SHH_DANRE
Sonic hedgehog protein A
Search

0.73	Sonic hedgehog protein A

0.74	GO:0007267	cell-cell signaling
0.73	GO:0016539	intein-mediated protein splicing
0.69	GO:0007275	multicellular organism development
0.52	GO:0007224	smoothened signaling pathway
0.51	GO:0045880	positive regulation of smoothened signaling pathway
0.51	GO:0033084	regulation of immature T cell proliferation in thymus
0.51	GO:0033089	positive regulation of T cell differentiation in thymus
0.51	GO:0001649	osteoblast differentiation
0.51	GO:0045165	cell fate commitment
0.51	GO:0046639	negative regulation of alpha-beta T cell differentiation

0.59	GO:0008233	peptidase activity
0.52	GO:0005113	patched binding
0.51	GO:0046872	metal ion binding
0.47	GO:0043237	laminin-1 binding
0.43	GO:0005539	glycosaminoglycan binding
0.36	GO:0016015	morphogen activity

0.68	GO:0005615	extracellular space
0.53	GO:0005886	plasma membrane
0.46	GO:0005578	proteinaceous extracellular matrix
0.44	GO:0098857	membrane microdomain
0.42	GO:0009986	cell surface
0.35	GO:0005622	intracellular
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon
0.34	GO:0098793	presynapse

0.59

GO:0008233

sp|Q92047|PIMT_DANRE
Protein-L-isoaspartate(D-aspartate) O-methyltransferase
Search

PCMT1

0.44	L-isoaspartyl protein carboxyl methyltransferase

0.73	GO:0008213	protein alkylation
0.67	GO:0043414	macromolecule methylation
0.35	GO:0010667	negative regulation of cardiac muscle cell apoptotic process
0.35	GO:0045471	response to ethanol
0.35	GO:0071456	cellular response to hypoxia
0.34	GO:0007568	aging
0.34	GO:0046498	S-adenosylhomocysteine metabolic process
0.34	GO:0030091	protein repair
0.34	GO:0046500	S-adenosylmethionine metabolic process

0.79	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity
0.36	GO:0045296	cadherin binding

0.47	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.35	GO:0031526	brush border membrane
0.35	GO:0043204	perikaryon
0.34	GO:0016323	basolateral plasma membrane
0.34	GO:0043005	neuron projection
0.30	GO:0016021	integral component of membrane

0.79

EC:2.1.1.77

GO:0004719

sp|Q92048|WNT2_DANRE
Protein Wnt-2
Search

sp|Q92050|WNT5B_DANRE
Protein Wnt-5b
Search

sp|Q92051|CAHZ_DANRE
Carbonic anhydrase
Search

CA2

0.43	Red blood cell carbonic anhydrase II

0.71	GO:0006730	one-carbon metabolic process
0.56	GO:0015670	carbon dioxide transport
0.51	GO:0044070	regulation of anion transport
0.50	GO:0038166	angiotensin-activated signaling pathway
0.50	GO:2000878	positive regulation of oligopeptide transport
0.50	GO:2001148	regulation of dipeptide transmembrane transport
0.50	GO:0032849	positive regulation of cellular pH reduction
0.49	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.48	GO:0042539	hypotonic salinity response
0.46	GO:0034764	positive regulation of transmembrane transport

0.77	GO:0004089	carbonate dehydratase activity
0.62	GO:0008270	zinc ion binding
0.49	GO:0004064	arylesterase activity
0.34	GO:0005515	protein binding

0.48	GO:0045177	apical part of cell
0.48	GO:0043209	myelin sheath
0.44	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane
0.38	GO:0005902	microvillus
0.37	GO:0030424	axon
0.36	GO:0005615	extracellular space
0.36	GO:0043227	membrane-bounded organelle
0.35	GO:0043230	extracellular organelle
0.34	GO:0043229	intracellular organelle

0.77

EC:4.2.1.1

GO:0004089

sp|Q92052|CXG1_DANRE
Gap junction gamma-1 protein
Search

0.64	Gap junction protein (Fragment)

0.60	GO:0007154	cell communication
0.52	GO:0016264	gap junction assembly
0.50	GO:0061337	cardiac conduction
0.50	GO:0001570	vasculogenesis
0.49	GO:0048738	cardiac muscle tissue development
0.47	GO:0007601	visual perception
0.46	GO:0048468	cell development
0.41	GO:0034220	ion transmembrane transport
0.34	GO:0086002	cardiac muscle cell action potential involved in contraction

0.53	GO:0086077	gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling
0.44	GO:0005216	ion channel activity
0.35	GO:0086020	gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling
0.33	GO:0005515	protein binding

0.83	GO:0005922	connexin complex
0.34	GO:0014704	intercalated disc
0.33	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

tr|Q95HJ4|Q95HJ4_DANRE
Novel protein similar to parts of MHC class II beta chain and MHC class II antigen
Search

0.94	Novel protein similar to parts of MHC class II beta chain and MHC class II antigen

0.75	GO:0019882	antigen processing and presentation
0.73	GO:0006955	immune response

0.75	GO:0042613	MHC class II protein complex
0.34	GO:0070062	extracellular exosome
0.34	GO:0045121	membrane raft
0.33	GO:0009986	cell surface
0.33	GO:0097708	intracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|Q98862|IHH_DANRE
Indian hedgehog B protein
Search

0.76	Sonic hedgehog protein A

0.74	GO:0016539	intein-mediated protein splicing
0.73	GO:0007267	cell-cell signaling
0.69	GO:0007275	multicellular organism development
0.59	GO:0007224	smoothened signaling pathway
0.59	GO:0001649	osteoblast differentiation
0.59	GO:0033084	regulation of immature T cell proliferation in thymus
0.58	GO:0033089	positive regulation of T cell differentiation in thymus
0.58	GO:0046639	negative regulation of alpha-beta T cell differentiation
0.57	GO:0045880	positive regulation of smoothened signaling pathway
0.57	GO:0002053	positive regulation of mesenchymal cell proliferation

0.59	GO:0008233	peptidase activity
0.59	GO:0005113	patched binding
0.52	GO:0046872	metal ion binding
0.49	GO:0043237	laminin-1 binding
0.44	GO:0005539	glycosaminoglycan binding
0.37	GO:0016015	morphogen activity
0.32	GO:0022857	transmembrane transporter activity

0.68	GO:0005615	extracellular space
0.53	GO:0005886	plasma membrane
0.51	GO:0005578	proteinaceous extracellular matrix
0.45	GO:0098857	membrane microdomain
0.44	GO:0009986	cell surface
0.35	GO:0005622	intracellular
0.34	GO:0012505	endomembrane system
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon

0.59

GO:0008233

sp|Q98864|PTC1_DANRE
Protein patched homolog 1
Search

PTCH1

0.93

Patched

0.60	GO:0007165	signal transduction
0.56	GO:0009957	epidermal cell fate specification
0.56	GO:0045879	negative regulation of smoothened signaling pathway
0.55	GO:0021997	neural plate axis specification
0.55	GO:0010157	response to chlorate
0.54	GO:0045606	positive regulation of epidermal cell differentiation
0.54	GO:0071397	cellular response to cholesterol
0.54	GO:0072203	cell proliferation involved in metanephros development
0.54	GO:0010875	positive regulation of cholesterol efflux
0.53	GO:0043616	keratinocyte proliferation

0.86	GO:0008158	hedgehog receptor activity
0.57	GO:0005119	smoothened binding
0.57	GO:0097108	hedgehog family protein binding
0.54	GO:0005113	patched binding
0.51	GO:0015485	cholesterol binding
0.51	GO:0030332	cyclin binding
0.50	GO:0008201	heparin binding
0.47	GO:0032403	protein complex binding
0.33	GO:0008270	zinc ion binding

0.51	GO:0005901	caveola
0.50	GO:0030496	midbody
0.49	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0005929	cilium
0.46	GO:0005794	Golgi apparatus
0.40	GO:0044294	dendritic growth cone
0.39	GO:0044295	axonal growth cone
0.38	GO:0014069	postsynaptic density
0.35	GO:0005634	nucleus
0.34	GO:0030666	endocytic vesicle membrane

tr|Q98865|Q98865_DANRE
Paired box 9
Search

PAX9

0.93	paired box protein Pax-9

0.74	GO:0009887	animal organ morphogenesis
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0042481	regulation of odontogenesis
0.52	GO:0060325	face morphogenesis
0.51	GO:0007492	endoderm development
0.49	GO:0071363	cellular response to growth factor stimulus
0.47	GO:0060022	hard palate development

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0005310	dicarboxylic acid transmembrane transporter activity
0.33	GO:0005249	voltage-gated potassium channel activity
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex
0.33	GO:0005743	mitochondrial inner membrane
0.33	GO:0005887	integral component of plasma membrane

sp|Q98867|THAA_DANRE
Thyroid hormone receptor alpha-A
Search

0.97	Thyroid hormone receptor alpha-A

0.80	GO:0030522	intracellular receptor signaling pathway
0.79	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.41	GO:0045925	positive regulation of female receptivity
0.41	GO:0008050	female courtship behavior
0.40	GO:0002155	regulation of thyroid hormone mediated signaling pathway
0.40	GO:0060509	Type I pneumocyte differentiation

0.85	GO:0004887	thyroid hormone receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.49	GO:0070324	thyroid hormone binding
0.41	GO:0002153	steroid receptor RNA activator RNA binding
0.39	GO:0031490	chromatin DNA binding
0.39	GO:0017025	TBP-class protein binding
0.38	GO:0019904	protein domain specific binding
0.38	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.35	GO:0042025	host cell nucleus
0.33	GO:0019012	virion
0.30	GO:0044425	membrane part

0.34

GO:0004713

tr|Q98871|Q98871_DANRE
Homeodomain protein Nkx2.3
Search

NKX2-3

0.96	LOW QUALITY PROTEIN: homeobox protein Nkx-2.3

0.60	GO:1903779	regulation of cardiac conduction
0.60	GO:0048513	animal organ development
0.58	GO:0060048	cardiac muscle contraction
0.58	GO:0072359	circulatory system development
0.57	GO:0035295	tube development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0009888	tissue development
0.54	GO:0042127	regulation of cell proliferation

0.64	GO:0043565	sequence-specific DNA binding
0.48	GO:0003700	DNA binding transcription factor activity
0.46	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003682	chromatin binding
0.44	GO:0001104	RNA polymerase II transcription cofactor activity
0.44	GO:0003690	double-stranded DNA binding
0.43	GO:0008134	transcription factor binding
0.43	GO:0042803	protein homodimerization activity
0.43	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.44	GO:0005667	transcription factor complex
0.43	GO:0032993	protein-DNA complex
0.39	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|Q98873|Q98873_DANRE
Homeodomain protein Nkx2.7
Search

0.93	Homeobox protein Nkx-2.6

0.72	GO:1903779	regulation of cardiac conduction
0.70	GO:0060048	cardiac muscle contraction
0.70	GO:0007507	heart development
0.61	GO:0060037	pharyngeal system development
0.60	GO:0006357	regulation of transcription by RNA polymerase II
0.60	GO:0014706	striated muscle tissue development
0.60	GO:0035295	tube development
0.59	GO:0051146	striated muscle cell differentiation
0.59	GO:0014855	striated muscle cell proliferation
0.59	GO:0048568	embryonic organ development

0.65	GO:0043565	sequence-specific DNA binding
0.54	GO:0003700	DNA binding transcription factor activity
0.51	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003682	chromatin binding
0.48	GO:0001104	RNA polymerase II transcription cofactor activity
0.47	GO:0003690	double-stranded DNA binding
0.47	GO:0042803	protein homodimerization activity
0.47	GO:0008134	transcription factor binding
0.47	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.48	GO:0005667	transcription factor complex
0.47	GO:0032993	protein-DNA complex
0.41	GO:0044446	intracellular organelle part
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q98874|ERH_DANRE
Enhancer of rudimentary homolog
Search

ERH

0.85	Enhancer of rudimentary homolog

0.84	GO:0045747	positive regulation of Notch signaling pathway
0.69	GO:0006221	pyrimidine nucleotide biosynthetic process
0.66	GO:0007049	cell cycle
0.35	GO:0001649	osteoblast differentiation
0.33	GO:0006213	pyrimidine nucleoside metabolic process

0.51	GO:0008327	methyl-CpG binding
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.51	GO:0034709	methylosome
0.49	GO:0030496	midbody
0.30	GO:0016020	membrane

sp|Q98875|DLX1A_DANRE
Homeobox protein Dlx1a
Search

DLX1

0.97	homeobox protein DLX-1

0.62	GO:1902871	positive regulation of amacrine cell differentiation
0.62	GO:0021893	cerebral cortex GABAergic interneuron fate commitment
0.61	GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment
0.61	GO:0048706	embryonic skeletal system development
0.60	GO:0046533	negative regulation of photoreceptor cell differentiation
0.60	GO:0048715	negative regulation of oligodendrocyte differentiation
0.59	GO:0021544	subpallium development
0.58	GO:0009954	proximal/distal pattern formation
0.58	GO:0009887	animal organ morphogenesis
0.58	GO:0045746	negative regulation of Notch signaling pathway

0.62	GO:0043565	sequence-specific DNA binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0003682	chromatin binding
0.51	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding
0.34	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding

0.60	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q98876|DLX2B_DANRE
Homeobox protein Dlx2b
Search

0.90	Distal-less homeo box 5

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0060166	olfactory pit development
0.51	GO:0097376	interneuron axon guidance
0.50	GO:0021889	olfactory bulb interneuron differentiation
0.49	GO:0001958	endochondral ossification
0.49	GO:0060325	face morphogenesis
0.48	GO:0060021	palate development
0.48	GO:0001649	osteoblast differentiation

0.65	GO:0043565	sequence-specific DNA binding
0.50	GO:0071837	HMG box domain binding
0.47	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.44	GO:0000785	chromatin
0.42	GO:0031974	membrane-enclosed lumen
0.36	GO:0005737	cytoplasm

sp|Q98877|DLX6A_DANRE
Homeobox protein Dlx6a
Search

0.95	homeobox protein DLX-6

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.52	GO:0035107	appendage morphogenesis
0.51	GO:0060322	head development
0.51	GO:0009887	animal organ morphogenesis
0.50	GO:0009790	embryo development
0.49	GO:1902871	positive regulation of amacrine cell differentiation
0.48	GO:0033338	medial fin development
0.48	GO:0048715	negative regulation of oligodendrocyte differentiation

0.62	GO:0043565	sequence-specific DNA binding
0.44	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003682	chromatin binding
0.43	GO:0003690	double-stranded DNA binding
0.34	GO:0008097	5S rRNA binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.33	GO:0005840	ribosome

sp|Q98878|DLX4B_DANRE
Homeobox protein Dlx4b
Search

0.90	Distal-less homeobox 4

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.53	GO:0048706	embryonic skeletal system development
0.50	GO:0021893	cerebral cortex GABAergic interneuron fate commitment
0.50	GO:1902871	positive regulation of amacrine cell differentiation
0.50	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain
0.49	GO:0009887	animal organ morphogenesis
0.49	GO:0048715	negative regulation of oligodendrocyte differentiation
0.49	GO:0046533	negative regulation of photoreceptor cell differentiation

0.63	GO:0043565	sequence-specific DNA binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.46	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0003682	chromatin binding
0.33	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.33	GO:0005515	protein binding

0.60

GO:0005634

nucleus

sp|Q98879|DLX4A_DANRE
Homeobox protein Dlx4a
Search

0.90	Distal-less homeobox 4

0.55	GO:0048706	embryonic skeletal system development
0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0021893	cerebral cortex GABAergic interneuron fate commitment
0.55	GO:1902871	positive regulation of amacrine cell differentiation
0.54	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain
0.53	GO:0048715	negative regulation of oligodendrocyte differentiation
0.53	GO:0046533	negative regulation of photoreceptor cell differentiation
0.52	GO:0021544	subpallium development

0.62	GO:0043565	sequence-specific DNA binding
0.52	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003690	double-stranded DNA binding
0.48	GO:0003682	chromatin binding
0.44	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0005515	protein binding

0.60

GO:0005634

nucleus

sp|Q98880|ACHA_DANRE
Acetylcholine receptor subunit alpha
Search

0.89	Cholinergic receptor nicotinic alpha polypeptide 1

0.80	GO:0060079	excitatory postsynaptic potential
0.64	GO:0007274	neuromuscular synaptic transmission
0.64	GO:0048630	skeletal muscle tissue growth
0.61	GO:0070050	neuron cellular homeostasis
0.61	GO:0003009	skeletal muscle contraction
0.61	GO:0019228	neuronal action potential
0.60	GO:0046716	muscle cell cellular homeostasis
0.60	GO:0034220	ion transmembrane transport
0.59	GO:0007528	neuromuscular junction development
0.59	GO:0050905	neuromuscular process

0.83	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.67	GO:0042166	acetylcholine binding
0.34	GO:0043565	sequence-specific DNA binding

0.79	GO:0045211	postsynaptic membrane
0.75	GO:0030054	cell junction
0.64	GO:0005892	acetylcholine-gated channel complex
0.59	GO:0031594	neuromuscular junction
0.54	GO:0009986	cell surface
0.34	GO:0005634	nucleus

sp|Q98SH9|HXC1A_DANRE
Homeobox protein Hox-C1a
Search

HOXC1A

0.54	Homeodomain protein (Fragment)

0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.48	GO:0048706	embryonic skeletal system development
0.46	GO:0007399	nervous system development
0.46	GO:0019233	sensory perception of pain
0.44	GO:0060876	semicircular canal formation
0.43	GO:0042473	outer ear morphogenesis
0.43	GO:0007634	optokinetic behavior
0.43	GO:0090103	cochlea morphogenesis

0.62	GO:0043565	sequence-specific DNA binding
0.39	GO:0042802	identical protein binding
0.34	GO:0004000	adenosine deaminase activity
0.32	GO:0003700	DNA binding transcription factor activity

0.59	GO:0005634	nucleus
0.41	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part

0.34

EC:3.5.4.4

GO:0004000

sp|Q98SI1|HXA1A_DANRE
Homeobox protein Hox-A1a
Search

HOXA1

0.86	homeobox protein Hox-A1

0.60	GO:0021598	abducens nerve morphogenesis
0.59	GO:0060876	semicircular canal formation
0.58	GO:0042473	outer ear morphogenesis
0.58	GO:0007634	optokinetic behavior
0.58	GO:0021603	cranial nerve formation
0.58	GO:0048702	embryonic neurocranium morphogenesis
0.57	GO:0090103	cochlea morphogenesis
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression

0.64	GO:0043565	sequence-specific DNA binding
0.50	GO:0042802	identical protein binding
0.34	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

sp|Q98SJ5|SIM1A_DANRE
Single-minded homolog 1-A
Search

SIM1

0.97	Single-minded like protein 1

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0035295	tube development
0.52	GO:0072073	kidney epithelium development
0.52	GO:0001823	mesonephros development
0.47	GO:0007399	nervous system development
0.45	GO:0009880	embryonic pattern specification
0.45	GO:0060541	respiratory system development

0.67	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.43	GO:0005667	transcription factor complex
0.40	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q98SP7|BBS2_DANRE
Bardet-Biedl syndrome 2 protein homolog
Search

BBS2

0.96	Bardet-Biedl syndrome 2 protein homolog

0.81	GO:1905515	non-motile cilium assembly
0.59	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway
0.59	GO:0060295	regulation of cilium movement involved in cell motility
0.59	GO:0014824	artery smooth muscle contraction
0.58	GO:0003356	regulation of cilium beat frequency
0.58	GO:0007288	sperm axoneme assembly
0.58	GO:0021756	striatum development
0.58	GO:0040015	negative regulation of multicellular organism growth
0.57	GO:0042311	vasodilation
0.57	GO:1990778	protein localization to cell periphery

0.57

GO:0001103

RNA polymerase II repressing transcription factor binding

0.80	GO:0034464	BBSome
0.74	GO:0060170	ciliary membrane
0.66	GO:0005815	microtubule organizing center
0.56	GO:0032420	stereocilium
0.56	GO:0005902	microvillus
0.55	GO:0031514	motile cilium
0.46	GO:0005737	cytoplasm

sp|Q98SR9|TWS1B_DANRE
Twisted gastrulation protein homolog 1-B
Search

TWSG1

0.97	Twisted gastrulation BMP signaling modulator 1

0.82	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation
0.77	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.76	GO:0030513	positive regulation of BMP signaling pathway
0.75	GO:0045668	negative regulation of osteoblast differentiation
0.74	GO:0007435	salivary gland morphogenesis
0.74	GO:0001707	mesoderm formation
0.74	GO:0030514	negative regulation of BMP signaling pathway
0.74	GO:0001818	negative regulation of cytokine production
0.73	GO:0007179	transforming growth factor beta receptor signaling pathway
0.73	GO:0030509	BMP signaling pathway

0.79

GO:0050431

transforming growth factor beta binding

0.64	GO:0005615	extracellular space
0.41	GO:1903561	extracellular vesicle
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

sp|Q98SV0|SELPB_DANRE
Selenoprotein Pb
Search

0.89	Selenoprotein Pb

0.33	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.33	GO:0018108	peptidyl-tyrosine phosphorylation
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.84	GO:0008430	selenium binding
0.34	GO:0008270	zinc ion binding
0.34	GO:0099600	transmembrane receptor activity
0.34	GO:0046983	protein dimerization activity
0.33	GO:0038023	signaling receptor activity
0.33	GO:0008134	transcription factor binding
0.33	GO:0004713	protein tyrosine kinase activity
0.32	GO:0003723	RNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.38	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.33

GO:0004713

sp|Q98SV1|SELPA_DANRE
Selenoprotein Pa
Search

0.83	Selenoprotein Pa

0.44	GO:0001887	selenium compound metabolic process
0.43	GO:0007626	locomotory behavior
0.43	GO:0007420	brain development
0.42	GO:0009791	post-embryonic development
0.42	GO:0040007	growth
0.42	GO:0019953	sexual reproduction
0.40	GO:0002576	platelet degranulation
0.37	GO:0010269	response to selenium ion
0.37	GO:0006979	response to oxidative stress
0.35	GO:0099132	ATP hydrolysis coupled cation transmembrane transport

0.84	GO:0008430	selenium binding
0.36	GO:0005515	protein binding
0.35	GO:0019829	cation-transporting ATPase activity
0.35	GO:0016151	nickel cation binding
0.34	GO:0015099	nickel cation transmembrane transporter activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0005576	extracellular region
0.41	GO:0031089	platelet dense granule lumen
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q98T96|Q98T96_DANRE
Cytochrome P450
Search

0.90	Cytochrome P450 family 2 subfamily J member 2

0.53	GO:0055114	oxidation-reduction process
0.43	GO:0019373	epoxygenase P450 pathway
0.40	GO:0043651	linoleic acid metabolic process
0.34	GO:0032526	response to retinoic acid
0.34	GO:0045471	response to ethanol
0.34	GO:0032496	response to lipopolysaccharide
0.34	GO:0007584	response to nutrient
0.34	GO:0043434	response to peptide hormone
0.33	GO:0014070	response to organic cyclic compound
0.33	GO:0006468	protein phosphorylation

0.70	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.43	GO:0008395	steroid hydroxylase activity
0.43	GO:0008392	arachidonic acid epoxygenase activity
0.40	GO:0071614	linoleic acid epoxygenase activity
0.35	GO:0019825	oxygen binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.33	GO:0005789	endoplasmic reticulum membrane
0.32	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.70

EC:1.14.14

GO:0016712

tr|Q98TH1|Q98TH1_DANRE
Homeobox protein six2.1
Search

SIX2

0.94	SIX homeobox 2

0.72	GO:0072074	kidney mesenchyme development
0.71	GO:0042474	middle ear morphogenesis
0.71	GO:0090189	regulation of branching involved in ureteric bud morphogenesis
0.69	GO:0008283	cell proliferation
0.69	GO:0072088	nephron epithelium morphogenesis
0.69	GO:0001656	metanephros development
0.68	GO:0048701	embryonic cranial skeleton morphogenesis
0.68	GO:0001708	cell fate specification
0.65	GO:0072038	mesenchymal stem cell maintenance involved in nephron morphogenesis
0.65	GO:0034504	protein localization to nucleus

0.66	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.65	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0032403	protein complex binding
0.54	GO:0008134	transcription factor binding
0.50	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.46	GO:0043233	organelle lumen
0.43	GO:0043232	intracellular non-membrane-bounded organelle
0.42	GO:0044446	intracellular organelle part

sp|Q98TT6|4EB3L_DANRE
Eukaryotic translation initiation factor 4E-binding protein 3-like
Search

0.91	Eukaryotic translation initiation factor 4E binding protein 3

0.82	GO:0045947	negative regulation of translational initiation
0.61	GO:0006413	translational initiation
0.47	GO:0035176	social behavior
0.46	GO:0008286	insulin receptor signaling pathway
0.46	GO:0007613	memory
0.46	GO:0019933	cAMP-mediated signaling
0.46	GO:0048167	regulation of synaptic plasticity
0.45	GO:0031929	TOR signaling
0.39	GO:0014743	regulation of muscle hypertrophy

0.86	GO:0008190	eukaryotic initiation factor 4E binding
0.61	GO:0003743	translation initiation factor activity
0.47	GO:0030371	translation repressor activity

0.36	GO:0005737	cytoplasm
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q98TU0|GDNF_DANRE
Glial cell line-derived neurotrophic factor
Search

GDNF

0.94	Glial cell line-derived neurotrophic factor

0.75	GO:0010469	regulation of receptor activity
0.57	GO:0021784	postganglionic parasympathetic fiber development
0.57	GO:0072107	positive regulation of ureteric bud formation
0.57	GO:0051940	regulation of catecholamine uptake involved in synaptic transmission
0.56	GO:0030432	peristalsis
0.56	GO:0032225	regulation of synaptic transmission, dopaminergic
0.56	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
0.55	GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
0.55	GO:0032770	positive regulation of monooxygenase activity
0.55	GO:0048485	sympathetic nervous system development

0.78	GO:0008083	growth factor activity
0.49	GO:0042803	protein homodimerization activity
0.35	GO:0030116	glial cell-derived neurotrophic factor receptor binding
0.35	GO:0019899	enzyme binding
0.34	GO:0005160	transforming growth factor beta receptor binding
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.34	GO:0043235	receptor complex
0.31	GO:0005622	intracellular
0.30	GO:0016020	membrane

tr|Q98TU2|Q98TU2_DANRE
Eomesa protein
Search

0.97	T-box transcription factor Eomesodermin

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0006355	regulation of transcription, DNA-templated
0.56	GO:0002302	CD8-positive, alpha-beta T cell differentiation involved in immune response
0.54	GO:0045165	cell fate commitment
0.54	GO:0007420	brain development
0.54	GO:0003002	regionalization
0.52	GO:0001706	endoderm formation
0.51	GO:0007498	mesoderm development
0.51	GO:1903508	positive regulation of nucleic acid-templated transcription
0.51	GO:0010628	positive regulation of gene expression

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0001102	RNA polymerase II activating transcription factor binding
0.44	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.42	GO:0003682	chromatin binding
0.35	GO:0019901	protein kinase binding
0.34	GO:0005452	inorganic anion exchanger activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding

0.61	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q98TU3|Q98TU3_DANRE
Adcyap1b protein
Search

0.94	Pituitary adenylate cyclase-activating polypeptide

0.76	GO:0010469	regulation of receptor activity
0.56	GO:0007218	neuropeptide signaling pathway
0.54	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production
0.52	GO:0007399	nervous system development
0.52	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.52	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.52	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.50	GO:0045860	positive regulation of protein kinase activity
0.49	GO:0120036	plasma membrane bounded cell projection organization
0.48	GO:0043547	positive regulation of GTPase activity

0.79	GO:0005179	hormone activity
0.54	GO:0051428	peptide hormone receptor binding
0.41	GO:0005057	signal transducer activity, downstream of receptor
0.40	GO:0031858	pituitary adenylate cyclase-activating polypeptide receptor binding

0.66	GO:0005576	extracellular region
0.38	GO:0043195	terminal bouton
0.36	GO:0005622	intracellular
0.35	GO:0070852	cell body fiber
0.35	GO:0043204	perikaryon
0.30	GO:0031224	intrinsic component of membrane

sp|Q98TW1|NCOA2_DANRE
Nuclear receptor coactivator 2
Search

NCOA2

0.86	Nuclear receptor coactivator 2

0.57	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.46	GO:0048511	rhythmic process
0.45	GO:1904017	cellular response to Thyroglobulin triiodothyronine
0.44	GO:0051254	positive regulation of RNA metabolic process
0.44	GO:0010557	positive regulation of macromolecule biosynthetic process
0.44	GO:0031328	positive regulation of cellular biosynthetic process
0.44	GO:0030522	intracellular receptor signaling pathway

0.85	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.82	GO:0035257	nuclear hormone receptor binding
0.67	GO:0046983	protein dimerization activity
0.44	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
0.44	GO:0017162	aryl hydrocarbon receptor binding
0.41	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.41	GO:0003682	chromatin binding
0.41	GO:0019904	protein domain specific binding

0.61	GO:0005634	nucleus
0.38	GO:0043233	organelle lumen
0.37	GO:0043234	protein complex
0.36	GO:0044446	intracellular organelle part
0.34	GO:0005737	cytoplasm

sp|Q98TZ8|FLOT2_DANRE
Flotillin-2a
Search

FLOT2

0.89	Dehydrogenase/reductase 13

0.84	GO:0044860	protein localization to plasma membrane raft
0.81	GO:1902992	negative regulation of amyloid precursor protein catabolic process
0.79	GO:0045661	regulation of myoblast differentiation
0.77	GO:0001765	membrane raft assembly
0.74	GO:0072659	protein localization to plasma membrane
0.71	GO:0050821	protein stabilization
0.69	GO:1903905	positive regulation of establishment of T cell polarity
0.61	GO:0010629	negative regulation of gene expression
0.52	GO:0007155	cell adhesion
0.48	GO:0034139	regulation of toll-like receptor 3 signaling pathway

0.67	GO:0046982	protein heterodimerization activity
0.55	GO:0035255	ionotropic glutamate receptor binding
0.53	GO:0002020	protease binding

0.83	GO:0016600	flotillin complex
0.81	GO:0002080	acrosomal membrane
0.80	GO:0001931	uropod
0.77	GO:0030139	endocytic vesicle
0.76	GO:0044291	cell-cell contact zone
0.74	GO:0005913	cell-cell adherens junction
0.74	GO:0030027	lamellipodium
0.74	GO:0016323	basolateral plasma membrane
0.72	GO:0030864	cortical actin cytoskeleton
0.71	GO:0005768	endosome

sp|Q98UK4|MAF_DANRE
Transcription factor Maf
Search

0.93	Basic domain leucine zipper transcription factor

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0006351	transcription, DNA-templated
0.52	GO:0048839	inner ear development
0.50	GO:0021572	rhombomere 6 development
0.49	GO:0021598	abducens nerve morphogenesis
0.49	GO:0045595	regulation of cell differentiation
0.49	GO:2000026	regulation of multicellular organismal development
0.49	GO:0035283	central nervous system segmentation

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.43	GO:0008134	transcription factor binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.44	GO:0005667	transcription factor complex
0.36	GO:0005737	cytoplasm
0.34	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome
0.33	GO:0042025	host cell nucleus

sp|Q98UK5|MAFB_DANRE
Transcription factor MafB
Search

0.93	V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:0021572	rhombomere 6 development
0.56	GO:0010468	regulation of gene expression
0.56	GO:0021571	rhombomere 5 development
0.52	GO:0048839	inner ear development
0.51	GO:0021598	abducens nerve morphogenesis
0.51	GO:0045647	negative regulation of erythrocyte differentiation
0.51	GO:1902680	positive regulation of RNA biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0008134	transcription factor binding
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.45	GO:0005667	transcription factor complex
0.35	GO:0005737	cytoplasm
0.34	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome
0.33	GO:0042025	host cell nucleus
0.30	GO:0016020	membrane

sp|Q9DDD7|SX19B_DANRE
Transcription factor Sox-19b
Search

SOX2

0.90	Sex determining region Y-box 2

0.54	GO:2001141	regulation of RNA biosynthetic process
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.51	GO:0021536	diencephalon development
0.50	GO:0001714	endodermal cell fate specification
0.49	GO:0035270	endocrine system development
0.49	GO:0035019	somatic stem cell population maintenance
0.48	GO:0001649	osteoblast differentiation
0.48	GO:0048839	inner ear development
0.48	GO:0050680	negative regulation of epithelial cell proliferation

0.55	GO:0003677	DNA binding
0.49	GO:0035198	miRNA binding
0.46	GO:0001067	regulatory region nucleic acid binding
0.42	GO:0003700	DNA binding transcription factor activity
0.37	GO:0003682	chromatin binding
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.43	GO:0005829	cytosol
0.42	GO:0070013	intracellular organelle lumen
0.39	GO:0044446	intracellular organelle part
0.39	GO:0005667	transcription factor complex

tr|Q9DDE0|Q9DDE0_DANRE
Meis2.1 protein
Search

MEIS2

0.86	Meis homeobox 2

0.67	GO:0110024	positive regulation of cardiac muscle myoblast proliferation
0.63	GO:0008542	visual learning
0.62	GO:0045638	negative regulation of myeloid cell differentiation
0.61	GO:0048513	animal organ development
0.60	GO:0045931	positive regulation of mitotic cell cycle
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0006366	transcription by RNA polymerase II
0.56	GO:0010468	regulation of gene expression
0.55	GO:1902680	positive regulation of RNA biosynthetic process

0.60	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.59	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0003712	transcription cofactor activity
0.54	GO:0008134	transcription factor binding

0.61

GO:0005634

nucleus

sp|Q9DDE3|ACES_DANRE
Acetylcholinesterase
Search

ACHE

0.38	Acetylcholinesterase

0.69	GO:0042135	neurotransmitter catabolic process
0.67	GO:0008291	acetylcholine metabolic process
0.60	GO:0045212	neurotransmitter receptor biosynthetic process
0.60	GO:0042447	hormone catabolic process
0.59	GO:0071405	cellular response to methanol
0.58	GO:0048468	cell development
0.57	GO:0050808	synapse organization
0.57	GO:0048731	system development
0.56	GO:0001975	response to amphetamine
0.56	GO:0001919	regulation of receptor recycling

0.84	GO:0004104	cholinesterase activity
0.57	GO:0042166	acetylcholine binding
0.56	GO:0043236	laminin binding
0.55	GO:0043621	protein self-association
0.54	GO:0005518	collagen binding
0.50	GO:0042803	protein homodimerization activity
0.48	GO:0001540	amyloid-beta binding
0.47	GO:0017171	serine hydrolase activity
0.42	GO:0033265	choline binding

0.69	GO:0045202	synapse
0.67	GO:0030054	cell junction
0.61	GO:0005576	extracellular region
0.54	GO:0031225	anchored component of membrane
0.52	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005886	plasma membrane
0.51	GO:0009986	cell surface
0.49	GO:0005794	Golgi apparatus
0.42	GO:0005788	endoplasmic reticulum lumen
0.42	GO:0005791	rough endoplasmic reticulum

0.84

EC:3.1.1.8

GO:0004104

tr|Q9DDE4|Q9DDE4_DANRE
Somatostatin
Search

0.76	Somatostatin

0.79	GO:0030334	regulation of cell migration
0.75	GO:0010469	regulation of receptor activity
0.75	GO:0007267	cell-cell signaling
0.71	GO:0007166	cell surface receptor signaling pathway

0.79

GO:0005179

hormone activity

0.73

GO:0005615

extracellular space

tr|Q9DDG2|Q9DDG2_DANRE
Midkine b
Search

MDK

0.97	Pleiotrophic factor-alpha-2

0.76	GO:0010469	regulation of receptor activity
0.53	GO:0030421	defecation
0.53	GO:0007399	nervous system development
0.52	GO:0060322	head development
0.52	GO:0007614	short-term memory
0.52	GO:0001662	behavioral fear response
0.51	GO:0009611	response to wounding
0.51	GO:0043524	negative regulation of neuron apoptotic process
0.50	GO:0050795	regulation of behavior
0.50	GO:0048513	animal organ development

0.78	GO:0008083	growth factor activity
0.51	GO:0008201	heparin binding
0.38	GO:0043395	heparan sulfate proteoglycan binding
0.33	GO:0016301	kinase activity

0.42	GO:0005576	extracellular region
0.36	GO:0005794	Golgi apparatus
0.35	GO:0042995	cell projection
0.34	GO:0009986	cell surface
0.30	GO:0016020	membrane

sp|Q9DDJ0|UBC9B_DANRE
SUMO-conjugating enzyme UBC9-B
Search

UBE2I

0.76	SUMO-conjugating enzyme UBC9-B

0.80	GO:0016925	protein sumoylation
0.48	GO:1903755	positive regulation of SUMO transferase activity
0.46	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.45	GO:0000122	negative regulation of transcription by RNA polymerase II
0.44	GO:0007059	chromosome segregation
0.42	GO:0051301	cell division
0.42	GO:0007049	cell cycle
0.38	GO:0060216	definitive hemopoiesis
0.36	GO:0061484	hematopoietic stem cell homeostasis
0.36	GO:0042359	vitamin D metabolic process

0.82	GO:0019789	SUMO transferase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0043398	HLH domain binding
0.48	GO:0071535	RING-like zinc finger domain binding
0.47	GO:0044388	small protein activating enzyme binding
0.46	GO:0061650	ubiquitin-like protein conjugating enzyme activity
0.44	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0061630	ubiquitin protein ligase activity

0.48	GO:1990356	sumoylated E2 ligase complex
0.45	GO:0016605	PML body
0.41	GO:0005829	cytosol
0.41	GO:1990234	transferase complex
0.37	GO:0005635	nuclear envelope
0.36	GO:0000795	synaptonemal complex
0.36	GO:0001650	fibrillar center
0.35	GO:0030425	dendrite
0.35	GO:0045202	synapse

0.35

GO:0016874

sp|Q9DDK4|S1PR1_DANRE
Sphingosine 1-phosphate receptor 1
Search

S1PR1

0.96	Sphingosine 1-phosphate receptor 1

0.84	GO:0003376	sphingosine-1-phosphate signaling pathway
0.58	GO:0003245	cardiac muscle tissue growth involved in heart morphogenesis
0.55	GO:0001955	blood vessel maturation
0.55	GO:0072678	T cell migration
0.55	GO:0045124	regulation of bone resorption
0.54	GO:0061384	heart trabecula morphogenesis
0.54	GO:0030032	lamellipodium assembly
0.53	GO:0030500	regulation of bone mineralization
0.53	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.53	GO:0030595	leukocyte chemotaxis

0.85	GO:0038036	sphingosine-1-phosphate receptor activity
0.52	GO:0001664	G-protein coupled receptor binding
0.39	GO:0046625	sphingolipid binding
0.36	GO:0070915	lysophosphatidic acid receptor activity
0.32	GO:0016491	oxidoreductase activity

0.52	GO:0009897	external side of plasma membrane
0.47	GO:0005654	nucleoplasm
0.46	GO:0031226	intrinsic component of plasma membrane
0.39	GO:0045121	membrane raft
0.38	GO:0005768	endosome
0.34	GO:0098590	plasma membrane region
0.30	GO:0016021	integral component of membrane

0.32

GO:0016491

tr|Q9DDL2|Q9DDL2_DANRE
MALT paracaspase 2
Search

MALT1

0.92	MALT paracaspase 2

0.77	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.67	GO:0001923	B-1 B cell differentiation
0.65	GO:0002726	positive regulation of T cell cytokine production
0.64	GO:0007250	activation of NF-kappaB-inducing kinase activity
0.64	GO:0032743	positive regulation of interleukin-2 production
0.63	GO:0042098	T cell proliferation
0.63	GO:0050856	regulation of T cell receptor signaling pathway
0.63	GO:0050852	T cell receptor signaling pathway
0.61	GO:0006508	proteolysis
0.60	GO:0009620	response to fungus

0.75	GO:0004197	cysteine-type endopeptidase activity
0.62	GO:0002020	protease binding
0.62	GO:0043621	protein self-association
0.61	GO:0019209	kinase activator activity
0.55	GO:0042802	identical protein binding
0.55	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0004871	signal transducer activity

0.66	GO:0032449	CBM complex
0.61	GO:0001650	fibrillar center
0.52	GO:0005829	cytosol

0.75	EC:3.4.22	GO:0004197
0.55	KEGG:R03876	GO:0004842

tr|Q9DDT0|Q9DDT0_DANRE
Ferritin
Search

0.55	Ferritin heavy chain

0.76	GO:0006879	cellular iron ion homeostasis
0.75	GO:0006826	iron ion transport
0.46	GO:0051238	sequestering of metal ion
0.44	GO:0051651	maintenance of location in cell
0.41	GO:0008285	negative regulation of cell proliferation
0.39	GO:0006955	immune response
0.38	GO:0048145	regulation of fibroblast proliferation
0.37	GO:0055114	oxidation-reduction process
0.35	GO:0060547	negative regulation of necrotic cell death
0.35	GO:0002446	neutrophil mediated immunity

0.75	GO:0008199	ferric iron binding
0.45	GO:0016724	oxidoreductase activity, oxidizing metal ions, oxygen as acceptor
0.34	GO:0005515	protein binding

0.39	GO:0044754	autolysosome
0.36	GO:0005739	mitochondrion
0.36	GO:0031982	vesicle
0.36	GO:0043230	extracellular organelle
0.35	GO:0070288	ferritin complex
0.35	GO:0005615	extracellular space
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0005634	nucleus
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005829	cytosol

0.45

EC:1.16.3

GO:0016724

sp|Q9DDT5|SPT5H_DANRE
Transcription elongation factor SPT5
Search

SUPT5H

0.66	Transcription elongation factor SPT5

0.71	GO:0032784	regulation of DNA-templated transcription, elongation
0.67	GO:0006357	regulation of transcription by RNA polymerase II
0.55	GO:0006414	translational elongation
0.55	GO:1900364	negative regulation of mRNA polyadenylation
0.54	GO:0006351	transcription, DNA-templated
0.52	GO:0016239	positive regulation of macroautophagy
0.48	GO:0045893	positive regulation of transcription, DNA-templated
0.47	GO:0045892	negative regulation of transcription, DNA-templated
0.43	GO:0006397	mRNA processing
0.36	GO:1902038	positive regulation of hematopoietic stem cell differentiation

0.56	GO:0003746	translation elongation factor activity
0.48	GO:0046982	protein heterodimerization activity
0.48	GO:0003682	chromatin binding
0.47	GO:0019899	enzyme binding
0.45	GO:0003729	mRNA binding
0.38	GO:0003677	DNA binding

0.57

GO:0032044

DSIF complex

sp|Q9DDU0|HXABA_DANRE
Homeobox protein Hox-A11a
Search

0.85	Homeobox protein Hox-A11

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.51	GO:0060272	embryonic skeletal joint morphogenesis
0.51	GO:0001759	organ induction
0.50	GO:0009954	proximal/distal pattern formation
0.50	GO:0042733	embryonic digit morphogenesis
0.49	GO:0001656	metanephros development
0.48	GO:0009952	anterior/posterior pattern specification
0.45	GO:1902680	positive regulation of RNA biosynthetic process

0.63	GO:0043565	sequence-specific DNA binding
0.45	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.44	GO:0001012	RNA polymerase II regulatory region DNA binding
0.42	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.43	GO:0031974	membrane-enclosed lumen
0.41	GO:0005829	cytosol
0.40	GO:0044446	intracellular organelle part
0.39	GO:0005667	transcription factor complex
0.39	GO:0032993	protein-DNA complex

sp|Q9DDU1|HXABB_DANRE
Homeobox protein Hox-A11b
Search

0.85	homeobox protein Hox-A11

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.44	GO:0060272	embryonic skeletal joint morphogenesis
0.44	GO:0007501	mesodermal cell fate specification
0.44	GO:0032332	positive regulation of chondrocyte differentiation
0.44	GO:0001759	organ induction
0.44	GO:0001658	branching involved in ureteric bud morphogenesis
0.44	GO:0060351	cartilage development involved in endochondral bone morphogenesis
0.44	GO:0035115	embryonic forelimb morphogenesis

0.64

GO:0043565

sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.42	GO:0031974	membrane-enclosed lumen
0.40	GO:0005667	transcription factor complex
0.40	GO:0032993	protein-DNA complex
0.39	GO:0044446	intracellular organelle part

tr|Q9DDU5|Q9DDU5_DANRE
Glutathione S-transferase pi
Search

GSTP1

0.41	Pi-class glutathione S-transferase

0.55	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process
0.55	GO:0071638	negative regulation of monocyte chemotactic protein-1 production
0.54	GO:0043508	negative regulation of JUN kinase activity
0.54	GO:0032691	negative regulation of interleukin-1 beta production
0.54	GO:0043651	linoleic acid metabolic process
0.53	GO:0032720	negative regulation of tumor necrosis factor production
0.52	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.52	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.50	GO:0071466	cellular response to xenobiotic stimulus
0.49	GO:0006749	glutathione metabolic process

0.78	GO:0004364	glutathione transferase activity
0.57	GO:0035730	S-nitrosoglutathione binding
0.51	GO:0035731	dinitrosyl-iron complex binding
0.50	GO:0004602	glutathione peroxidase activity
0.39	GO:0008432	JUN kinase binding
0.38	GO:0043295	glutathione binding
0.37	GO:0019207	kinase regulator activity
0.36	GO:0070026	nitric oxide binding
0.34	GO:0010181	FMN binding
0.34	GO:0008144	drug binding

0.56	GO:0097057	TRAF2-GSTP1 complex
0.46	GO:0005829	cytosol
0.45	GO:0098788	dendritic knob
0.45	GO:0005739	mitochondrion
0.43	GO:0071683	sensory dendrite
0.41	GO:0097014	ciliary plasm
0.41	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen

0.78

EC:2.5.1.18

GO:0004364

sp|Q9DE24|FXC1B_DANRE
Forkhead box C1-B
Search

0.82	Forkhead box protein C2-B

0.59	GO:0014032	neural crest cell development
0.58	GO:1902257	negative regulation of apoptotic process involved in outflow tract morphogenesis
0.58	GO:0072010	glomerular epithelium development
0.57	GO:0003018	vascular process in circulatory system
0.57	GO:0001944	vasculature development
0.57	GO:0043010	camera-type eye development
0.56	GO:0001756	somitogenesis
0.56	GO:0048341	paraxial mesoderm formation
0.56	GO:0008015	blood circulation
0.55	GO:0060038	cardiac muscle cell proliferation

0.62	GO:0043565	sequence-specific DNA binding
0.59	GO:0003700	DNA binding transcription factor activity
0.56	GO:1990841	promoter-specific chromatin binding
0.51	GO:0044212	transcription regulatory region DNA binding
0.50	GO:0031490	chromatin DNA binding
0.46	GO:0042802	identical protein binding
0.45	GO:0001223	transcription coactivator binding
0.43	GO:0008301	DNA binding, bending
0.42	GO:0003713	transcription coactivator activity
0.40	GO:0003690	double-stranded DNA binding

0.59	GO:0005634	nucleus
0.46	GO:0070013	intracellular organelle lumen
0.42	GO:0000792	heterochromatin
0.40	GO:0005829	cytosol

sp|Q9DE25|FXC1A_DANRE
Forkhead box C1-A
Search

0.93	Forkhead box protein C1-A

0.58	GO:0014032	neural crest cell development
0.57	GO:0072010	glomerular epithelium development
0.56	GO:0003018	vascular process in circulatory system
0.56	GO:0043010	camera-type eye development
0.56	GO:0001944	vasculature development
0.56	GO:0001756	somitogenesis
0.56	GO:0008015	blood circulation
0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:1902257	negative regulation of apoptotic process involved in outflow tract morphogenesis

0.63	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.53	GO:1990841	promoter-specific chromatin binding
0.49	GO:0044212	transcription regulatory region DNA binding
0.47	GO:0031490	chromatin DNA binding
0.44	GO:0001223	transcription coactivator binding
0.44	GO:0042802	identical protein binding
0.43	GO:0008301	DNA binding, bending
0.42	GO:0003713	transcription coactivator activity
0.39	GO:0003690	double-stranded DNA binding

0.59	GO:0005634	nucleus
0.44	GO:0070013	intracellular organelle lumen
0.42	GO:0000792	heterochromatin
0.39	GO:0005829	cytosol

tr|Q9DE40|Q9DE40_DANRE
Zic family member 2 (Odd-paired homolog, Drosophila) b
Search

0.66	Zinc finger protein ZIC 2-A

0.55	GO:0007417	central nervous system development
0.55	GO:0060322	head development
0.53	GO:0048513	animal organ development
0.50	GO:0048598	embryonic morphogenesis
0.49	GO:0048385	regulation of retinoic acid receptor signaling pathway
0.48	GO:0048863	stem cell differentiation
0.47	GO:0043009	chordate embryonic development
0.47	GO:1904888	cranial skeletal system development
0.47	GO:0001501	skeletal system development
0.46	GO:0008589	regulation of smoothened signaling pathway

0.50	GO:0003676	nucleic acid binding
0.43	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0003682	chromatin binding
0.35	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.45	GO:0005634	nucleus
0.41	GO:0070013	intracellular organelle lumen
0.38	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9DE49|PGFRA_DANRE
Platelet-derived growth factor receptor alpha
Search

PDGFRA

0.68	Platelet-derived growth factor receptor alpha

0.84	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.65	GO:0006935	chemotaxis
0.64	GO:0007275	multicellular organism development
0.56	GO:0023019	signal transduction involved in regulation of gene expression
0.56	GO:0008210	estrogen metabolic process
0.55	GO:0060325	face morphogenesis
0.55	GO:0060021	palate development
0.55	GO:1904888	cranial skeletal system development
0.54	GO:0022602	ovulation cycle process

0.85	GO:0005017	platelet-derived growth factor-activated receptor activity
0.58	GO:0048407	platelet-derived growth factor binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0038085	vascular endothelial growth factor binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0005161	platelet-derived growth factor receptor binding
0.50	GO:0032403	protein complex binding
0.49	GO:0005021	vascular endothelial growth factor-activated receptor activity

0.54	GO:0005902	microvillus
0.53	GO:0009897	external side of plasma membrane
0.48	GO:0043202	lysosomal lumen
0.44	GO:0030054	cell junction
0.44	GO:0005634	nucleus
0.43	GO:0031226	intrinsic component of plasma membrane
0.43	GO:0031410	cytoplasmic vesicle
0.40	GO:0043234	protein complex
0.37	GO:0005794	Golgi apparatus
0.34	GO:0030424	axon

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

tr|Q9DEG7|Q9DEG7_DANRE
C-terminal-binding protein 1
Search

CTBP1

0.87	C-terminal-binding protein 1

0.53	GO:0055114	oxidation-reduction process
0.51	GO:1903756	regulation of transcription from RNA polymerase II promoter by histone modification
0.50	GO:0090241	negative regulation of histone H4 acetylation
0.49	GO:0031065	positive regulation of histone deacetylation
0.49	GO:0050872	white fat cell differentiation
0.46	GO:0000122	negative regulation of transcription by RNA polymerase II
0.45	GO:0048384	retinoic acid receptor signaling pathway
0.44	GO:0051726	regulation of cell cycle
0.35	GO:0099526	presynapse to nucleus signaling pathway
0.34	GO:0008285	negative regulation of cell proliferation

0.68	GO:0051287	NAD binding
0.66	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.49	GO:0003714	transcription corepressor activity
0.48	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.48	GO:0070491	repressing transcription factor binding
0.46	GO:0001104	RNA polymerase II transcription cofactor activity
0.45	GO:0019904	protein domain specific binding
0.43	GO:0042803	protein homodimerization activity
0.40	GO:0003700	DNA binding transcription factor activity
0.34	GO:0008022	protein C-terminus binding

0.47	GO:0017053	transcriptional repressor complex
0.44	GO:0005667	transcription factor complex
0.43	GO:0005654	nucleoplasm
0.41	GO:0005829	cytosol
0.34	GO:0098793	presynapse

0.66

EC:1.1.1

GO:0016616

tr|Q9DES8|Q9DES8_DANRE
Glycine receptor betaZ subunit (Fragment)
Search

GLRB

0.96	Glycine receptor subunit beta

0.77	GO:0060079	excitatory postsynaptic potential
0.75	GO:1902476	chloride transmembrane transport
0.60	GO:0060012	synaptic transmission, glycinergic
0.59	GO:0097112	gamma-aminobutyric acid receptor clustering
0.58	GO:0060013	righting reflex
0.57	GO:0001964	startle response
0.56	GO:0007628	adult walking behavior
0.56	GO:0007340	acrosome reaction
0.55	GO:0007218	neuropeptide signaling pathway
0.52	GO:0007601	visual perception

0.85	GO:0016934	extracellularly glycine-gated chloride channel activity
0.68	GO:0099600	transmembrane receptor activity
0.63	GO:0038023	signaling receptor activity
0.59	GO:0016594	glycine binding
0.35	GO:0005515	protein binding

0.77	GO:0045211	postsynaptic membrane
0.59	GO:0016935	glycine-gated chloride channel complex
0.59	GO:0098982	GABA-ergic synapse
0.39	GO:0030425	dendrite
0.38	GO:0030054	cell junction
0.35	GO:0043204	perikaryon
0.35	GO:0009897	external side of plasma membrane
0.34	GO:0005783	endoplasmic reticulum

sp|Q9DEX7|FADS2_DANRE
Fatty acid desaturase 2
Search

0.45	Fatty acid desaturase

0.63	GO:0006629	lipid metabolic process
0.52	GO:0055114	oxidation-reduction process
0.41	GO:0072330	monocarboxylic acid biosynthetic process
0.36	GO:0017144	drug metabolic process
0.35	GO:0001889	liver development

0.53	GO:0016491	oxidoreductase activity
0.33	GO:0020037	heme binding
0.32	GO:0046872	metal ion binding

0.37	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005887	integral component of plasma membrane

0.53

GO:0016491

tr|Q9DF30|Q9DF30_DANRE
Gap junction protein
Search

0.60	Gap junction protein (Fragment)

0.60	GO:0007154	cell communication
0.47	GO:0050908	detection of light stimulus involved in visual perception
0.45	GO:0007416	synapse assembly
0.44	GO:0007276	gamete generation
0.39	GO:0055085	transmembrane transport

0.50	GO:0005243	gap junction channel activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.83	GO:0005922	connexin complex
0.30	GO:0016021	integral component of membrane

tr|Q9DF41|Q9DF41_DANRE
BHLH-WRPW transcription factor
Search

HES1

0.85	BHLH-WRPW transcription factor

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0050767	regulation of neurogenesis
0.54	GO:0051961	negative regulation of nervous system development
0.54	GO:0010721	negative regulation of cell development
0.53	GO:0007219	Notch signaling pathway
0.52	GO:0021536	diencephalon development
0.51	GO:0043009	chordate embryonic development

0.68	GO:0046983	protein dimerization activity
0.55	GO:0003677	DNA binding
0.48	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0042826	histone deacetylase binding
0.45	GO:0051087	chaperone binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.45	GO:0042802	identical protein binding
0.39	GO:0008134	transcription factor binding
0.35	GO:0008432	JUN kinase binding
0.34	GO:0004565	beta-galactosidase activity

0.61	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome
0.30	GO:0016020	membrane

0.34

EC:3.2.1.23

GO:0004565

tr|Q9DF53|Q9DF53_DANRE
Sodium channel protein
Search

0.52	Calcium-transporting ATPase

0.77	GO:0035725	sodium ion transmembrane transport
0.76	GO:0034765	regulation of ion transmembrane transport
0.44	GO:0019228	neuronal action potential
0.44	GO:0086010	membrane depolarization during action potential
0.40	GO:0007626	locomotory behavior
0.39	GO:0007638	mechanosensory behavior
0.39	GO:0030537	larval behavior
0.39	GO:0008045	motor neuron axon guidance
0.37	GO:0050905	neuromuscular process
0.36	GO:0030534	adult behavior

0.84	GO:0005248	voltage-gated sodium channel activity
0.73	GO:0022832	voltage-gated channel activity
0.71	GO:0022839	ion gated channel activity
0.71	GO:0008381	mechanosensitive ion channel activity
0.44	GO:0005509	calcium ion binding
0.35	GO:0005388	calcium-transporting ATPase activity
0.35	GO:0031402	sodium ion binding
0.34	GO:0005515	protein binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding

0.84	GO:0001518	voltage-gated sodium channel complex
0.37	GO:0033268	node of Ranvier
0.37	GO:0030018	Z disc
0.36	GO:0043025	neuronal cell body
0.36	GO:0030425	dendrite
0.35	GO:0043194	axon initial segment
0.31	GO:0031410	cytoplasmic vesicle

0.35

EC:3.6.3.8

GO:0005388

tr|Q9DFC7|Q9DFC7_DANRE
Odorant receptor
Search

0.41	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:1903955	positive regulation of protein targeting to mitochondrion

0.76	GO:0004984	olfactory receptor activity
0.63	GO:0004930	G-protein coupled receptor activity
0.34	GO:0005549	odorant binding

0.50	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q9DFC9|Q9DFC9_DANRE
Fibroblast growth factor
Search

0.62	Fibroblast growth factor

0.79	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.58	GO:0001502	cartilage condensation
0.55	GO:0008284	positive regulation of cell proliferation
0.53	GO:0060591	chondroblast differentiation
0.53	GO:2000544	regulation of endothelial cell chemotaxis to fibroblast growth factor
0.52	GO:0010463	mesenchymal cell proliferation
0.51	GO:0060363	cranial suture morphogenesis
0.50	GO:0060561	apoptotic process involved in morphogenesis
0.50	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.81	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0004713	protein tyrosine kinase activity
0.34	GO:0008201	heparin binding

0.64	GO:0005576	extracellular region
0.37	GO:0042383	sarcolemma
0.32	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|Q9DFG8|MKRN2_DANRE
Probable E3 ubiquitin-protein ligase makorin-2
Search

MKRN2

0.97	Makorin ring finger protein 2

0.41	GO:0016567	protein ubiquitination
0.38	GO:0007399	nervous system development
0.38	GO:0030154	cell differentiation
0.37	GO:0043491	protein kinase B signaling
0.37	GO:0014065	phosphatidylinositol 3-kinase signaling
0.36	GO:0009798	axis specification
0.36	GO:0051961	negative regulation of nervous system development
0.36	GO:0010721	negative regulation of cell development
0.36	GO:0009792	embryo development ending in birth or egg hatching
0.35	GO:1990823	response to leukemia inhibitory factor

0.54	GO:0046872	metal ion binding
0.51	GO:0016874	ligase activity
0.37	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0003682	chromatin binding
0.34	GO:0003723	RNA binding
0.34	GO:0000213	tRNA-intron endonuclease activity
0.33	GO:0005515	protein binding

0.37

GO:0005622

intracellular

0.51	EC:6	GO:0016874
0.37	KEGG:R03876	GO:0004842

tr|Q9DFH1|Q9DFH1_DANRE
HMG box transcription factor Sox9b
Search

0.93	SRY sex determining region Y-box 9

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.53	GO:0030916	otic vesicle formation
0.51	GO:0061448	connective tissue development
0.49	GO:0001501	skeletal system development
0.48	GO:0060485	mesenchyme development
0.48	GO:0035107	appendage morphogenesis
0.48	GO:0003170	heart valve development
0.47	GO:0060041	retina development in camera-type eye
0.47	GO:0031018	endocrine pancreas development
0.47	GO:0060788	ectodermal placode formation

0.73	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.55	GO:0003677	DNA binding
0.44	GO:0034236	protein kinase A catalytic subunit binding
0.44	GO:0003682	chromatin binding
0.44	GO:0097157	pre-mRNA intronic binding
0.43	GO:0001067	regulatory region nucleic acid binding
0.42	GO:0008013	beta-catenin binding
0.41	GO:0046982	protein heterodimerization activity
0.38	GO:0004672	protein kinase activity
0.37	GO:0044389	ubiquitin-like protein ligase binding

0.61	GO:0005634	nucleus
0.41	GO:0005667	transcription factor complex
0.39	GO:0070013	intracellular organelle lumen
0.37	GO:0044446	intracellular organelle part
0.35	GO:0005737	cytoplasm

tr|Q9DFH2|Q9DFH2_DANRE
HMG box transcription factor Sox9a
Search

0.93	SRY sex determining region Y-box 9

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.57	GO:0030916	otic vesicle formation
0.55	GO:0060767	epithelial cell proliferation involved in prostate gland development
0.55	GO:2000741	positive regulation of mesenchymal stem cell differentiation
0.55	GO:0060784	regulation of cell proliferation involved in tissue homeostasis
0.55	GO:0051216	cartilage development
0.55	GO:0060516	primary prostatic bud elongation
0.55	GO:2000020	positive regulation of male gonad development
0.54	GO:0072289	metanephric nephron tubule formation
0.54	GO:0019100	male germ-line sex determination

0.73	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.55	GO:0003677	DNA binding
0.52	GO:0003682	chromatin binding
0.51	GO:0034236	protein kinase A catalytic subunit binding
0.51	GO:0097157	pre-mRNA intronic binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.48	GO:0008013	beta-catenin binding
0.45	GO:0046982	protein heterodimerization activity
0.43	GO:0004672	protein kinase activity
0.38	GO:0043425	bHLH transcription factor binding

0.61	GO:0005634	nucleus
0.45	GO:0005667	transcription factor complex
0.43	GO:0070013	intracellular organelle lumen
0.40	GO:0044446	intracellular organelle part
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9DFI0|DMT3B_DANRE
Doublesex- and mab-3-related transcription factor 3b (Fragment)
Search

0.96	Doublesex-and Mab 3-related transcription factor (Fragment)

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0048665	neuron fate specification
0.49	GO:0003002	regionalization
0.49	GO:0007417	central nervous system development
0.48	GO:0060573	cell fate specification involved in pattern specification
0.47	GO:0042487	regulation of odontogenesis of dentin-containing tooth
0.47	GO:0048513	animal organ development
0.47	GO:0019226	transmission of nerve impulse

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0046872	metal ion binding
0.46	GO:0046982	protein heterodimerization activity
0.41	GO:0042803	protein homodimerization activity
0.33	GO:0044212	transcription regulatory region DNA binding
0.33	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|Q9DFS2|Q9DFS2_DANRE
Biklf
Search

0.81	Blood island enriched kruppel like factor

0.52	GO:0030218	erythrocyte differentiation
0.50	GO:0071499	cellular response to laminar fluid shear stress
0.48	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.48	GO:0060509	Type I pneumocyte differentiation
0.48	GO:0045893	positive regulation of transcription, DNA-templated
0.48	GO:0048785	hatching gland development
0.47	GO:0035188	hatching
0.47	GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress
0.46	GO:0061515	myeloid cell development
0.46	GO:0035264	multicellular organism growth

0.51	GO:0003676	nucleic acid binding
0.44	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting
0.34	GO:0005515	protein binding
0.34	GO:1990841	promoter-specific chromatin binding
0.34	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.33	GO:0046872	metal ion binding

0.45	GO:0000790	nuclear chromatin
0.34	GO:0000791	euchromatin
0.33	GO:0044798	nuclear transcription factor complex
0.33	GO:0005654	nucleoplasm
0.32	GO:0005737	cytoplasm

sp|Q9DFS4|STAR3_DANRE
StAR-related lipid transfer protein 3
Search

STARD3

0.94	StAR related lipid transfer domain containing 3

0.72	GO:0030301	cholesterol transport
0.61	GO:0099044	vesicle tethering to endoplasmic reticulum
0.59	GO:0006701	progesterone biosynthetic process
0.35	GO:0008203	cholesterol metabolic process
0.35	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.35	GO:0006839	mitochondrial transport
0.33	GO:0007165	signal transduction

0.73	GO:0017127	cholesterol transporter activity
0.72	GO:0015485	cholesterol binding
0.52	GO:0042803	protein homodimerization activity
0.35	GO:0004864	protein phosphatase inhibitor activity

0.69	GO:0005770	late endosome
0.55	GO:0044232	organelle membrane contact site
0.54	GO:0010008	endosome membrane
0.50	GO:0005789	endoplasmic reticulum membrane
0.44	GO:0005739	mitochondrion
0.35	GO:0005765	lysosomal membrane
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q9DFS6|IF4EA_DANRE
Eukaryotic translation initiation factor 4E-1A
Search

EIF4E

0.79	Eukaryotic translation initiation factor 4ea

0.72	GO:0006413	translational initiation
0.51	GO:0071549	cellular response to dexamethasone stimulus
0.51	GO:0001662	behavioral fear response
0.49	GO:0019827	stem cell population maintenance
0.49	GO:0045665	negative regulation of neuron differentiation
0.47	GO:0000082	G1/S transition of mitotic cell cycle
0.47	GO:0017148	negative regulation of translation
0.46	GO:0045931	positive regulation of mitotic cell cycle
0.38	GO:0030324	lung development
0.35	GO:0010507	negative regulation of autophagy

0.73	GO:0003743	translation initiation factor activity
0.71	GO:0031370	eukaryotic initiation factor 4G binding
0.67	GO:0070491	repressing transcription factor binding
0.57	GO:0019899	enzyme binding
0.49	GO:0000340	RNA 7-methylguanosine cap binding

0.63	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005845	mRNA cap binding complex
0.51	GO:0033391	chromatoid body
0.50	GO:0016281	eukaryotic translation initiation factor 4F complex
0.47	GO:0016442	RISC complex
0.46	GO:0000932	P-body
0.46	GO:0010494	cytoplasmic stress granule
0.43	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus

tr|Q9DFZ0|Q9DFZ0_DANRE
BMP and activin membrane-bound inhibitor homolog
Search

BAMBI

0.97	BMP and activin membrane-bound inhibitor

0.84	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.83	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.57	GO:0035413	positive regulation of catenin import into nucleus
0.56	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.55	GO:0032092	positive regulation of protein binding
0.52	GO:0008284	positive regulation of cell proliferation
0.52	GO:0016477	cell migration
0.50	GO:0045893	positive regulation of transcription, DNA-templated
0.48	GO:0008360	regulation of cell shape
0.39	GO:0030514	negative regulation of BMP signaling pathway

0.56	GO:0005109	frizzled binding
0.35	GO:0005114	type II transforming growth factor beta receptor binding

0.42	GO:0005886	plasma membrane
0.39	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q9DG10|STAR_DANRE
Steroidogenic acute regulatory protein, mitochondrial
Search

STAR

0.93	Steroidogenic acute regulatory protein long form

0.83	GO:0030301	cholesterol transport
0.76	GO:0006694	steroid biosynthetic process
0.59	GO:1904253	positive regulation of bile acid metabolic process
0.58	GO:0070857	regulation of bile acid biosynthetic process
0.58	GO:0008211	glucocorticoid metabolic process
0.57	GO:0010893	positive regulation of steroid biosynthetic process
0.49	GO:0031328	positive regulation of cellular biosynthetic process
0.45	GO:0044255	cellular lipid metabolic process
0.45	GO:0008203	cholesterol metabolic process
0.40	GO:0042747	circadian sleep/wake cycle, REM sleep

0.85	GO:0017127	cholesterol transporter activity
0.82	GO:0015485	cholesterol binding
0.34	GO:0005515	protein binding

0.60	GO:0005739	mitochondrion
0.38	GO:0043025	neuronal cell body
0.37	GO:0031970	organelle envelope lumen
0.37	GO:0043005	neuron projection
0.36	GO:0005829	cytosol
0.35	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

sp|Q9DG12|ARNT2_DANRE
Aryl hydrocarbon receptor nuclear translocator 2
Search

ARNT2

0.96	Aryl hydrocarbon receptor nuclear translocator 2

0.56	GO:0006351	transcription, DNA-templated
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.51	GO:0014070	response to organic cyclic compound
0.50	GO:0009410	response to xenobiotic stimulus
0.50	GO:0001666	response to hypoxia
0.49	GO:0007420	brain development
0.47	GO:0051254	positive regulation of RNA metabolic process
0.46	GO:0010557	positive regulation of macromolecule biosynthetic process

0.66	GO:0046983	protein dimerization activity
0.61	GO:0017162	aryl hydrocarbon receptor binding
0.60	GO:0003700	DNA binding transcription factor activity
0.54	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.50	GO:0001047	core promoter binding
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.34	GO:0070491	repressing transcription factor binding

0.73	GO:0005667	transcription factor complex
0.60	GO:0005634	nucleus
0.54	GO:0034751	aryl hydrocarbon receptor complex
0.48	GO:0005737	cytoplasm
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part

tr|Q9DG41|Q9DG41_DANRE
Hyaluronan synthase 2
Search

HAS2

0.94	Hyaluronan synthase 2

0.86	GO:0030213	hyaluronan biosynthetic process
0.62	GO:0085029	extracellular matrix assembly
0.60	GO:0036302	atrioventricular canal development
0.57	GO:0045226	extracellular polysaccharide biosynthetic process
0.56	GO:1900623	regulation of monocyte aggregation
0.55	GO:0003007	heart morphogenesis
0.55	GO:0036120	cellular response to platelet-derived growth factor stimulus
0.55	GO:0071498	cellular response to fluid shear stress
0.54	GO:0001568	blood vessel development
0.54	GO:0070295	renal water absorption

0.85

GO:0050501

hyaluronan synthase activity

0.64	GO:0005887	integral component of plasma membrane
0.52	GO:0036117	hyaluranon cable
0.40	GO:0005737	cytoplasm

0.85

EC:2.4.1.212

GO:0050501

sp|Q9DGD9|MK08_DANRE
Mitogen-activated protein kinase 8
Search

0.58	Mitogen-activated protein kinase

0.80	GO:0000165	MAPK cascade
0.53	GO:1902595	regulation of DNA replication origin binding
0.52	GO:0090045	positive regulation of deacetylase activity
0.52	GO:0031098	stress-activated protein kinase signaling cascade
0.51	GO:0009612	response to mechanical stimulus
0.51	GO:0031063	regulation of histone deacetylation
0.50	GO:0031281	positive regulation of cyclase activity
0.50	GO:0071276	cellular response to cadmium ion
0.50	GO:0034198	cellular response to amino acid starvation
0.50	GO:0032091	negative regulation of protein binding

0.82	GO:0004707	MAP kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0035033	histone deacetylase regulator activity
0.50	GO:0042826	histone deacetylase binding
0.34	GO:0019894	kinesin binding

0.45	GO:0005622	intracellular
0.43	GO:0043005	neuron projection
0.40	GO:0043227	membrane-bounded organelle
0.36	GO:0036477	somatodendritic compartment
0.36	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0044297	cell body
0.34	GO:0044422	organelle part
0.33	GO:0043234	protein complex
0.33	GO:0043228	non-membrane-bounded organelle

0.82	EC:2.7.11.24	GO:0004707
0.82	KEGG:R00162	GO:0004707

sp|Q9DGE0|MP2K6_DANRE
Dual specificity mitogen-activated protein kinase kinase 6
Search

MAP2K6

0.69	Dual specificity mitogen-activated protein kinase kinase 6

0.63	GO:0006468	protein phosphorylation
0.53	GO:0060048	cardiac muscle contraction
0.53	GO:0032147	activation of protein kinase activity
0.52	GO:0043406	positive regulation of MAP kinase activity
0.48	GO:0031098	stress-activated protein kinase signaling cascade
0.44	GO:0042981	regulation of apoptotic process
0.44	GO:0007346	regulation of mitotic cell cycle
0.41	GO:0072709	cellular response to sorbitol
0.40	GO:0032308	positive regulation of prostaglandin secretion
0.40	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process

0.65	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0019901	protein kinase binding
0.43	GO:0004708	MAP kinase kinase activity
0.36	GO:0004713	protein tyrosine kinase activity
0.36	GO:0042802	identical protein binding

0.45	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.36	GO:0005856	cytoskeleton
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.65

GO:0004674

sp|Q9DGE1|MK14B_DANRE
Mitogen-activated protein kinase 14B
Search

MAPK14

0.58	Mitogen-activated protein kinase

0.79	GO:0000165	MAPK cascade
0.57	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration
0.57	GO:2001184	positive regulation of interleukin-12 secretion
0.56	GO:1901741	positive regulation of myoblast fusion
0.56	GO:0090336	positive regulation of brown fat cell differentiation
0.56	GO:1905050	positive regulation of metallopeptidase activity
0.56	GO:0045663	positive regulation of myoblast differentiation
0.56	GO:0002741	positive regulation of cytokine secretion involved in immune response
0.55	GO:0090400	stress-induced premature senescence
0.55	GO:0071223	cellular response to lipoteichoic acid

0.81	GO:0004707	MAP kinase activity
0.56	GO:0048273	mitogen-activated protein kinase p38 binding
0.56	GO:0051525	NFAT protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.52	GO:0019903	protein phosphatase binding
0.35	GO:0004708	MAP kinase kinase activity
0.34	GO:0008022	protein C-terminus binding

0.51	GO:0016607	nuclear speck
0.50	GO:0000922	spindle pole
0.46	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.30	GO:0044425	membrane part

0.81	EC:2.7.11.24	GO:0004707
0.81	KEGG:R00162	GO:0004707

sp|Q9DGE2|MK14A_DANRE
Mitogen-activated protein kinase 14A
Search

MAPK14

0.58	Mitogen-activated protein kinase

0.79	GO:0000165	MAPK cascade
0.57	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration
0.57	GO:2001184	positive regulation of interleukin-12 secretion
0.57	GO:1901741	positive regulation of myoblast fusion
0.56	GO:0090336	positive regulation of brown fat cell differentiation
0.56	GO:1905050	positive regulation of metallopeptidase activity
0.56	GO:0045663	positive regulation of myoblast differentiation
0.56	GO:0002741	positive regulation of cytokine secretion involved in immune response
0.56	GO:0090400	stress-induced premature senescence
0.56	GO:0071223	cellular response to lipoteichoic acid

0.81	GO:0004707	MAP kinase activity
0.57	GO:0048273	mitogen-activated protein kinase p38 binding
0.57	GO:0051525	NFAT protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.52	GO:0019903	protein phosphatase binding
0.35	GO:0004708	MAP kinase kinase activity
0.34	GO:0008022	protein C-terminus binding

0.51	GO:0016607	nuclear speck
0.51	GO:0000922	spindle pole
0.46	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.30	GO:0044425	membrane part

0.81	EC:2.7.11.24	GO:0004707
0.81	KEGG:R00162	GO:0004707

sp|Q9DGH0|TWS1A_DANRE
Twisted gastrulation protein homolog 1-A
Search

TWSG1

0.97	Twisted gastrulation BMP signaling modulator 1

0.83	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation
0.77	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.76	GO:0030513	positive regulation of BMP signaling pathway
0.76	GO:0045668	negative regulation of osteoblast differentiation
0.75	GO:0007435	salivary gland morphogenesis
0.74	GO:0001707	mesoderm formation
0.74	GO:0030514	negative regulation of BMP signaling pathway
0.74	GO:0001818	negative regulation of cytokine production
0.74	GO:0007179	transforming growth factor beta receptor signaling pathway
0.74	GO:0030509	BMP signaling pathway

0.79

GO:0050431

transforming growth factor beta binding

0.65	GO:0005615	extracellular space
0.41	GO:1903561	extracellular vesicle
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

tr|Q9DGI4|Q9DGI4_DANRE
Sodium/potassium-transporting ATPase subunit beta
Search

0.79	Sodium/potassium-transporting ATPase subunit beta

0.72	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.59	GO:1903288	positive regulation of potassium ion import
0.59	GO:1903278	positive regulation of sodium ion export across plasma membrane
0.58	GO:0006883	cellular sodium ion homeostasis
0.57	GO:0086009	membrane repolarization
0.57	GO:1901018	positive regulation of potassium ion transmembrane transporter activity
0.56	GO:0030007	cellular potassium ion homeostasis
0.55	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.55	GO:0140115	export across plasma membrane

0.56	GO:0051117	ATPase binding
0.55	GO:0005391	sodium:potassium-exchanging ATPase activity
0.54	GO:0001671	ATPase activator activity

0.84	GO:0005890	sodium:potassium-exchanging ATPase complex
0.49	GO:0016324	apical plasma membrane
0.38	GO:0005737	cytoplasm
0.36	GO:0005901	caveola
0.35	GO:0097708	intracellular vesicle
0.35	GO:0070062	extracellular exosome

0.55

GO:0005391

sp|Q9DGJ3|NPC2_DANRE
Epididymal secretory protein E1
Search

NPC2

0.93	NPC intracellular cholesterol transporter 2

0.85	GO:0032367	intracellular cholesterol transport
0.54	GO:0033344	cholesterol efflux
0.51	GO:0042632	cholesterol homeostasis
0.48	GO:0009615	response to virus
0.42	GO:0008203	cholesterol metabolic process
0.35	GO:0046836	glycolipid transport
0.35	GO:0034383	low-density lipoprotein particle clearance
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0019747	regulation of isoprenoid metabolic process
0.34	GO:0015914	phospholipid transport

0.52	GO:0015485	cholesterol binding
0.52	GO:0017127	cholesterol transporter activity
0.46	GO:0019899	enzyme binding

0.49	GO:0005764	lysosome
0.46	GO:0005615	extracellular space
0.39	GO:0005783	endoplasmic reticulum
0.35	GO:0034774	secretory granule lumen
0.35	GO:0005775	vacuolar lumen
0.34	GO:1903561	extracellular vesicle

tr|Q9DGJ4|Q9DGJ4_DANRE
Odc1 protein
Search

ODC1

0.48	Ornithine decarboxylase

0.74	GO:0006596	polyamine biosynthetic process
0.55	GO:0009445	putrescine metabolic process
0.54	GO:0001822	kidney development
0.53	GO:0006591	ornithine metabolic process
0.53	GO:0042176	regulation of protein catabolic process
0.52	GO:0008284	positive regulation of cell proliferation
0.52	GO:0009615	response to virus
0.46	GO:0042462	eye photoreceptor cell development
0.35	GO:1902269	positive regulation of polyamine transmembrane transport
0.35	GO:0006521	regulation of cellular amino acid metabolic process

0.59	GO:0004586	ornithine decarboxylase activity
0.51	GO:0042803	protein homodimerization activity
0.35	GO:0042978	ornithine decarboxylase activator activity

0.48	GO:0005829	cytosol
0.38	GO:0048471	perinuclear region of cytoplasm

0.59	EC:4.1.1.17	GO:0004586
0.59	KEGG:R00670	GO:0004586

sp|Q9DGK4|TCTP_DANRE
Translationally-controlled tumor protein homolog
Search

TPT1

0.75	Translationally-controlled tumor

0.68	GO:2000384	negative regulation of ectoderm development
0.61	GO:0019827	stem cell population maintenance
0.55	GO:0030154	cell differentiation
0.40	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.38	GO:0006874	cellular calcium ion homeostasis
0.38	GO:0009615	response to virus
0.38	GO:0006816	calcium ion transport
0.37	GO:0002181	cytoplasmic translation
0.36	GO:0006457	protein folding
0.36	GO:0034599	cellular response to oxidative stress

0.57	GO:0008017	microtubule binding
0.55	GO:0008134	transcription factor binding
0.54	GO:0005509	calcium ion binding
0.37	GO:0051082	unfolded protein binding
0.35	GO:0003723	RNA binding

0.58	GO:0005615	extracellular space
0.58	GO:0005829	cytosol
0.53	GO:0005654	nucleoplasm
0.50	GO:0045298	tubulin complex
0.48	GO:0005771	multivesicular body
0.38	GO:1903561	extracellular vesicle
0.37	GO:0010494	cytoplasmic stress granule
0.34	GO:0005840	ribosome
0.34	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

tr|Q9DGL3|Q9DGL3_DANRE
Sodium/potassium-transporting ATPase subunit beta
Search

0.79	Sodium/potassium-transporting ATPase subunit beta

0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.57	GO:1903281	positive regulation of calcium:sodium antiporter activity
0.57	GO:1903288	positive regulation of potassium ion import
0.57	GO:1903275	positive regulation of sodium ion export
0.57	GO:1903276	regulation of sodium ion export across plasma membrane
0.56	GO:0006883	cellular sodium ion homeostasis
0.56	GO:0055119	relaxation of cardiac muscle
0.56	GO:0086009	membrane repolarization
0.56	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling

0.55	GO:0005391	sodium:potassium-exchanging ATPase activity
0.54	GO:0051117	ATPase binding
0.53	GO:0008022	protein C-terminus binding
0.52	GO:0001671	ATPase activator activity
0.52	GO:0031402	sodium ion binding
0.50	GO:0019901	protein kinase binding
0.50	GO:0030955	potassium ion binding
0.41	GO:0030554	adenyl nucleotide binding
0.40	GO:0097367	carbohydrate derivative binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding

0.85	GO:0005890	sodium:potassium-exchanging ATPase complex
0.54	GO:0014704	intercalated disc
0.54	GO:0042383	sarcolemma
0.52	GO:0043209	myelin sheath
0.52	GO:0016323	basolateral plasma membrane
0.52	GO:0016324	apical plasma membrane
0.39	GO:0005901	caveola
0.37	GO:0005622	intracellular
0.36	GO:0070062	extracellular exosome

0.55

GO:0005391

tr|Q9DGL6|Q9DGL6_DANRE
Sodium/potassium-transporting ATPase subunit alpha
Search

0.64	Sodium/potassium-transporting ATPase subunit alpha

0.84	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.75	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.72	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.43	GO:0021591	ventricular system development
0.43	GO:0006883	cellular sodium ion homeostasis
0.43	GO:0060974	cell migration involved in heart formation
0.42	GO:0030916	otic vesicle formation
0.42	GO:0030917	midbrain-hindbrain boundary development
0.42	GO:0048840	otolith development

0.85	GO:0005391	sodium:potassium-exchanging ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0046872	metal ion binding
0.39	GO:1990239	steroid hormone binding
0.39	GO:0051087	chaperone binding
0.37	GO:0001540	amyloid-beta binding
0.36	GO:0016791	phosphatase activity

0.45	GO:0042383	sarcolemma
0.41	GO:0005890	sodium:potassium-exchanging ATPase complex
0.40	GO:0043209	myelin sheath
0.40	GO:0016323	basolateral plasma membrane
0.39	GO:0097458	neuron part
0.38	GO:0032279	asymmetric synapse
0.38	GO:0099572	postsynaptic specialization
0.38	GO:0016324	apical plasma membrane
0.37	GO:0044297	cell body
0.36	GO:0120025	plasma membrane bounded cell projection

0.85

GO:0005391

tr|Q9DGM2|Q9DGM2_DANRE
Endothelin receptor B
Search

EDNRB

0.91	Endothelin receptor type B

0.82	GO:0086100	endothelin receptor signaling pathway
0.81	GO:0048484	enteric nervous system development
0.79	GO:0042310	vasoconstriction
0.77	GO:0008217	regulation of blood pressure
0.59	GO:0035645	enteric smooth muscle cell differentiation
0.59	GO:0007497	posterior midgut development
0.58	GO:0050931	pigment cell differentiation
0.58	GO:0014043	negative regulation of neuron maturation
0.57	GO:0048246	macrophage chemotaxis
0.57	GO:0014821	phasic smooth muscle contraction

0.82	GO:0004962	endothelin receptor activity
0.56	GO:0017046	peptide hormone binding
0.40	GO:0031702	type 1 angiotensin receptor binding

0.42	GO:0005886	plasma membrane
0.38	GO:0098857	membrane microdomain
0.38	GO:0031965	nuclear membrane
0.30	GO:0016021	integral component of membrane

tr|Q9DGM8|Q9DGM8_DANRE
Ventral homeobox
Search

0.97	homeobox protein VENTX

0.57	GO:0042663	regulation of endodermal cell fate specification
0.57	GO:0042661	regulation of mesodermal cell fate specification
0.55	GO:0009953	dorsal/ventral pattern formation
0.52	GO:2001141	regulation of RNA biosynthetic process
0.52	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.40	GO:0009653	anatomical structure morphogenesis
0.39	GO:0009790	embryo development
0.39	GO:0009888	tissue development
0.38	GO:0031128	developmental induction

0.58	GO:0043565	sequence-specific DNA binding
0.49	GO:0042803	protein homodimerization activity
0.48	GO:0046982	protein heterodimerization activity
0.37	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.36	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.35	GO:0001012	RNA polymerase II regulatory region DNA binding
0.35	GO:0003682	chromatin binding
0.35	GO:0016301	kinase activity
0.34	GO:0003690	double-stranded DNA binding
0.33	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.35	GO:0036464	cytoplasmic ribonucleoprotein granule
0.34	GO:0005829	cytosol
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

0.33

EC:2.7.7.7

GO:0003887

tr|Q9DGM9|Q9DGM9_DANRE
Homeobox protein Vega2
Search

0.92	Ventral expressed homeobox

0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.49	GO:0042663	regulation of endodermal cell fate specification
0.48	GO:0042661	regulation of mesodermal cell fate specification
0.48	GO:0009953	dorsal/ventral pattern formation
0.42	GO:0048663	neuron fate commitment
0.41	GO:0048513	animal organ development
0.41	GO:0060322	head development
0.41	GO:0007417	central nervous system development

0.63	GO:0043565	sequence-specific DNA binding
0.41	GO:0042803	protein homodimerization activity
0.41	GO:0046982	protein heterodimerization activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.36	GO:0003700	DNA binding transcription factor activity
0.34	GO:0016301	kinase activity

0.61	GO:0005634	nucleus
0.37	GO:0005667	transcription factor complex
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q9I879|Q9I879_DANRE
Aryl hydrocarbon receptor nuclear translocator-like 1a
Search

ARNTL

0.93	Aryl hydrocarbon receptor nuclear translocator like

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0090403	oxidative stress-induced premature senescence
0.56	GO:2001016	positive regulation of skeletal muscle cell differentiation
0.56	GO:2000074	regulation of type B pancreatic cell development
0.56	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway
0.55	GO:0060137	maternal process involved in parturition
0.55	GO:0007623	circadian rhythm

0.68	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0017162	aryl hydrocarbon receptor binding
0.54	GO:0070888	E-box binding
0.53	GO:0043425	bHLH transcription factor binding
0.53	GO:0051879	Hsp90 protein binding
0.52	GO:0070491	repressing transcription factor binding
0.52	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.52	GO:0001047	core promoter binding
0.37	GO:0003682	chromatin binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.55	GO:0033391	chromatoid body
0.46	GO:0043233	organelle lumen
0.43	GO:0044446	intracellular organelle part
0.36	GO:0005694	chromosome
0.33	GO:0005829	cytosol

sp|Q9I8K8|S1PR2_DANRE
Sphingosine 1-phosphate receptor 2
Search

S1PR2

0.96	Sphingosine 1-phosphate receptor 2

0.85	GO:0003376	sphingosine-1-phosphate signaling pathway
0.54	GO:1903142	positive regulation of establishment of endothelial barrier
0.54	GO:0090394	negative regulation of excitatory postsynaptic potential
0.53	GO:0046847	filopodium assembly
0.53	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.51	GO:0031532	actin cytoskeleton reorganization
0.49	GO:0003007	heart morphogenesis
0.49	GO:0035676	anterior lateral line neuromast hair cell development
0.48	GO:0001944	vasculature development
0.48	GO:0035677	posterior lateral line neuromast hair cell development

0.86	GO:0038036	sphingosine-1-phosphate receptor activity
0.53	GO:0001664	G-protein coupled receptor binding
0.51	GO:0005178	integrin binding
0.35	GO:0008289	lipid binding
0.34	GO:0003886	DNA (cytosine-5-)-methyltransferase activity
0.34	GO:0004977	melanocortin receptor activity
0.34	GO:0003682	chromatin binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0003677	DNA binding
0.32	GO:0016491	oxidoreductase activity

0.43	GO:0009897	external side of plasma membrane
0.40	GO:0005654	nucleoplasm
0.39	GO:0031226	intrinsic component of plasma membrane
0.35	GO:0098857	membrane microdomain
0.35	GO:0005768	endosome
0.30	GO:0016021	integral component of membrane

0.34

EC:2.1.1.37

GO:0003886

sp|Q9I8L5|FA10A_DANRE
Fatty acid-binding protein 10-A, liver basic
Search

0.80	Liver-basic fatty acid binding protein b

0.36	GO:0006869	lipid transport
0.35	GO:0043484	regulation of RNA splicing
0.34	GO:0051603	proteolysis involved in cellular protein catabolic process

0.72	GO:0008289	lipid binding
0.51	GO:0032052	bile acid binding
0.35	GO:0043178	alcohol binding
0.34	GO:0070003	threonine-type peptidase activity
0.33	GO:0019842	vitamin binding
0.33	GO:0004175	endopeptidase activity
0.32	GO:0003676	nucleic acid binding

0.36	GO:0005737	cytoplasm
0.34	GO:0005839	proteasome core complex
0.30	GO:0016020	membrane

sp|Q9I8N6|CSF1R_DANRE
Macrophage colony-stimulating factor 1 receptor
Search

0.66	Macrophage colony stimulating factor receptor

0.79	GO:0019221	cytokine-mediated signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.76	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.53	GO:0036006	cellular response to macrophage colony-stimulating factor stimulus
0.52	GO:0090197	positive regulation of chemokine secretion
0.52	GO:0045217	cell-cell junction maintenance
0.52	GO:0030316	osteoclast differentiation
0.51	GO:0031529	ruffle organization
0.51	GO:2000249	regulation of actin cytoskeleton reorganization
0.51	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein

0.84	GO:0019955	cytokine binding
0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0019903	protein phosphatase binding
0.46	GO:0042803	protein homodimerization activity

0.53	GO:1990682	CSF1-CSF1R complex
0.46	GO:0009986	cell surface
0.44	GO:0005654	nucleoplasm
0.40	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.80

EC:2.7.10.1

GO:0004714

tr|Q9I8N9|Q9I8N9_DANRE
Brain-type fatty acid binding protein
Search

FABP7

0.81	Fatty acid-binding protein, retina

0.52	GO:0060134	prepulse inhibition
0.51	GO:0021846	cell proliferation in forebrain
0.47	GO:0022008	neurogenesis
0.37	GO:0061024	membrane organization
0.37	GO:0050673	epithelial cell proliferation
0.37	GO:0042632	cholesterol homeostasis
0.37	GO:2001245	regulation of phosphatidylcholine biosynthetic process
0.37	GO:0055091	phospholipid homeostasis
0.37	GO:0044539	long-chain fatty acid import
0.37	GO:0050727	regulation of inflammatory response

0.72	GO:0008289	lipid binding
0.39	GO:0033293	monocarboxylic acid binding
0.35	GO:0008092	cytoskeletal protein binding
0.34	GO:0008134	transcription factor binding
0.32	GO:0016787	hydrolase activity

0.49	GO:0043025	neuronal cell body
0.47	GO:0005911	cell-cell junction
0.44	GO:0042995	cell projection
0.40	GO:0043209	myelin sheath
0.39	GO:0071944	cell periphery
0.35	GO:0005615	extracellular space
0.34	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.32

GO:0016787

sp|Q9I8P2|PYYA_DANRE
Peptide YY-A
Search

NPY

0.89	Prepro-neuropeptide Y

0.76	GO:0010469	regulation of receptor activity
0.68	GO:0007218	neuropeptide signaling pathway
0.51	GO:0021954	central nervous system neuron development
0.51	GO:0021987	cerebral cortex development
0.50	GO:0008217	regulation of blood pressure
0.49	GO:0032098	regulation of appetite
0.48	GO:0031175	neuron projection development
0.48	GO:0007631	feeding behavior
0.44	GO:0007267	cell-cell signaling
0.41	GO:0032097	positive regulation of response to food

0.79	GO:0005179	hormone activity
0.56	GO:0001664	G-protein coupled receptor binding
0.34	GO:0005246	calcium channel regulator activity
0.33	GO:0004930	G-protein coupled receptor activity

0.66	GO:0005576	extracellular region
0.46	GO:0005794	Golgi apparatus
0.34	GO:0043204	perikaryon
0.34	GO:0043195	terminal bouton
0.34	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016020	membrane

sp|Q9I8P3|NPY_DANRE
Pro-neuropeptide Y
Search

NPY

0.95	Prepro-neuropeptide Y

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0007218	neuropeptide signaling pathway
0.51	GO:0021954	central nervous system neuron development
0.51	GO:0021987	cerebral cortex development
0.51	GO:0008217	regulation of blood pressure
0.49	GO:0031175	neuron projection development
0.47	GO:0032098	regulation of appetite
0.46	GO:0007631	feeding behavior
0.43	GO:0007267	cell-cell signaling
0.41	GO:0032097	positive regulation of response to food

0.79	GO:0005179	hormone activity
0.53	GO:0001664	G-protein coupled receptor binding
0.34	GO:0005246	calcium channel regulator activity
0.33	GO:0004930	G-protein coupled receptor activity

0.66	GO:0005576	extracellular region
0.46	GO:0005794	Golgi apparatus
0.34	GO:0043204	perikaryon
0.34	GO:0043195	terminal bouton
0.34	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016020	membrane

tr|Q9I8U7|Q9I8U7_DANRE
Fast skeletal muscle myosin light polypeptide 3
Search

0.91	Fast skeletal muscle myosin light polypeptide 3

0.35	GO:0060047	heart contraction
0.35	GO:0048738	cardiac muscle tissue development
0.35	GO:0003007	heart morphogenesis
0.35	GO:0061061	muscle structure development
0.34	GO:0002026	regulation of the force of heart contraction
0.34	GO:0055006	cardiac cell development
0.34	GO:0006942	regulation of striated muscle contraction
0.34	GO:0006941	striated muscle contraction
0.34	GO:0061817	endoplasmic reticulum-plasma membrane tethering
0.34	GO:0003231	cardiac ventricle development

0.70	GO:0005509	calcium ion binding
0.34	GO:0003785	actin monomer binding
0.34	GO:0008307	structural constituent of muscle

0.36	GO:0016459	myosin complex
0.35	GO:0044449	contractile fiber part
0.35	GO:0030016	myofibril
0.34	GO:0005903	brush border

tr|Q9I8U8|Q9I8U8_DANRE
Fast skeletal muscle troponin C
Search

TNNC2

0.93	Fast skeletal muscle troponin C

0.55	GO:0006941	striated muscle contraction
0.54	GO:0050881	musculoskeletal movement
0.47	GO:0006937	regulation of muscle contraction
0.46	GO:0014823	response to activity
0.42	GO:0060047	heart contraction
0.38	GO:0003231	cardiac ventricle development
0.35	GO:0030049	muscle filament sliding
0.34	GO:0014883	transition between fast and slow fiber
0.34	GO:1903115	regulation of actin filament-based movement
0.34	GO:0003229	ventricular cardiac muscle tissue development

0.70	GO:0005509	calcium ion binding
0.49	GO:0003779	actin binding
0.48	GO:0048306	calcium-dependent protein binding
0.44	GO:0032403	protein complex binding
0.37	GO:0031014	troponin T binding
0.34	GO:0031013	troponin I binding
0.34	GO:0047617	acyl-CoA hydrolase activity
0.33	GO:0042803	protein homodimerization activity

0.53	GO:0036379	myofilament
0.52	GO:0030017	sarcomere
0.49	GO:0015629	actin cytoskeleton
0.47	GO:0044430	cytoskeletal part
0.43	GO:0043234	protein complex
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.1.2 EC:3.1.2.20

GO:0047617

sp|Q9I8V0|PRV2_DANRE
Parvalbumin-2
Search

0.89	Parvalbumin alpha

0.70

GO:0005509

calcium ion binding

0.42	GO:0043679	axon terminus
0.41	GO:0030425	dendrite
0.41	GO:0030424	axon
0.37	GO:0016528	sarcoplasm

tr|Q9I8V1|Q9I8V1_DANRE
Actin, alpha 1, skeletal muscle
Search

0.59	Fast skeletal muscle alpha-actin

0.55	GO:0072132	mesenchyme morphogenesis
0.52	GO:0090130	tissue migration
0.47	GO:0010628	positive regulation of gene expression
0.46	GO:0030240	skeletal muscle thin filament assembly
0.43	GO:0014706	striated muscle tissue development
0.43	GO:0007517	muscle organ development
0.43	GO:0014904	myotube cell development
0.42	GO:0048747	muscle fiber development
0.42	GO:0007507	heart development
0.38	GO:0033275	actin-myosin filament sliding

0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0017022	myosin binding
0.36	GO:0017056	structural constituent of nuclear pore
0.34	GO:0016887	ATPase activity

0.52	GO:0030175	filopodium
0.52	GO:0030027	lamellipodium
0.51	GO:0044297	cell body
0.45	GO:0005856	cytoskeleton
0.43	GO:0030017	sarcomere
0.42	GO:0036379	myofilament
0.38	GO:0044446	intracellular organelle part
0.35	GO:0072562	blood microparticle
0.34	GO:0070062	extracellular exosome
0.34	GO:0043234	protein complex

0.34

GO:0016887

sp|Q9I8V2|SMAD1_DANRE
Mothers against decapentaplegic homolog 1
Search

SMAD1

0.64	Mothers against decapentaplegic homolog

0.83	GO:0007179	transforming growth factor beta receptor signaling pathway
0.63	GO:0002051	osteoblast fate commitment
0.61	GO:0030509	BMP signaling pathway
0.60	GO:0045669	positive regulation of osteoblast differentiation
0.60	GO:0060395	SMAD protein signal transduction
0.59	GO:0001657	ureteric bud development
0.59	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
0.58	GO:0060348	bone development
0.58	GO:0051216	cartilage development
0.58	GO:0006351	transcription, DNA-templated

0.62	GO:0017151	DEAD/H-box RNA helicase binding
0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0070410	co-SMAD binding
0.51	GO:0070878	primary miRNA binding
0.51	GO:0070411	I-SMAD binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0019901	protein kinase binding
0.46	GO:0046982	protein heterodimerization activity
0.46	GO:0042803	protein homodimerization activity

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.46	GO:0070013	intracellular organelle lumen
0.45	GO:0044446	intracellular organelle part
0.43	GO:0012505	endomembrane system
0.41	GO:0031090	organelle membrane
0.40	GO:0031975	envelope
0.37	GO:0071141	SMAD protein complex
0.30	GO:0016021	integral component of membrane

sp|Q9I8X3|FGFR3_DANRE
Fibroblast growth factor receptor 3
Search

FGFR3

0.66	Fibroblast growth factor receptor

0.82	GO:0008543	fibroblast growth factor receptor signaling pathway
0.78	GO:0008284	positive regulation of cell proliferation
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.54	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
0.54	GO:0010518	positive regulation of phospholipase activity
0.53	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.53	GO:0097191	extrinsic apoptotic signaling pathway
0.52	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.51	GO:0046777	protein autophosphorylation
0.41	GO:0070977	bone maturation

0.85	GO:0005007	fibroblast growth factor-activated receptor activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0017134	fibroblast growth factor binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0042802	identical protein binding
0.40	GO:0004908	interleukin-1 receptor activity
0.37	GO:0008083	growth factor activity
0.35	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity

0.49	GO:0030133	transport vesicle
0.47	GO:0005794	Golgi apparatus
0.46	GO:0005783	endoplasmic reticulum
0.45	GO:0005887	integral component of plasma membrane
0.39	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005764	lysosome
0.39	GO:0009898	cytoplasmic side of plasma membrane
0.39	GO:0009986	cell surface
0.36	GO:0005634	nucleus
0.35	GO:0005925	focal adhesion

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

tr|Q9I903|Q9I903_DANRE
Beta-catenin-interacting protein
Search

CTNNBIP1

0.93	Beta-catenin-interacting protein 1

0.59	GO:0002528	regulation of vascular permeability involved in acute inflammatory response
0.58	GO:0072201	negative regulation of mesenchymal cell proliferation
0.58	GO:0045657	positive regulation of monocyte differentiation
0.58	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter
0.58	GO:0001658	branching involved in ureteric bud morphogenesis
0.56	GO:0045669	positive regulation of osteoblast differentiation
0.56	GO:0048662	negative regulation of smooth muscle cell proliferation
0.55	GO:0030178	negative regulation of Wnt signaling pathway
0.55	GO:0043392	negative regulation of DNA binding
0.55	GO:0009952	anterior/posterior pattern specification

0.84	GO:0008013	beta-catenin binding
0.58	GO:0070016	armadillo repeat domain binding
0.39	GO:0042988	X11-like protein binding
0.38	GO:0001540	amyloid-beta binding
0.38	GO:0019894	kinesin binding
0.37	GO:0005509	calcium ion binding
0.33	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0016301	kinase activity

0.58	GO:0030877	beta-catenin destruction complex
0.49	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.37	GO:0014069	postsynaptic density
0.37	GO:0045211	postsynaptic membrane
0.36	GO:0009986	cell surface
0.36	GO:0005615	extracellular space
0.34	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.34	GO:0070013	intracellular organelle lumen
0.30	GO:0016021	integral component of membrane

sp|Q9I918|GP173_DANRE
Probable G-protein coupled receptor 173
Search

GPR173

0.83	G-protein coupled receptor 173

0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.56	GO:0097211	cellular response to gonadotropin-releasing hormone
0.51	GO:2001223	negative regulation of neuron migration

0.70	GO:0004930	G-protein coupled receptor activity
0.54	GO:0016500	protein-hormone receptor activity

0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q9I919|GPR85_DANRE
Probable G protein-coupled receptor 85
Search

SREB2

0.67	Super conserved receptor expressed in brain 2 (Fragment)

0.67

GO:0007186

G-protein coupled receptor signaling pathway

0.68

GO:0004930

G-protein coupled receptor activity

0.30

GO:0044425

membrane part

tr|Q9I9B7|Q9I9B7_DANRE
Pbx1a homeodomain protein
Search

PBX1

0.88	PBX homeobox 1

0.66	GO:0030325	adrenal gland development
0.65	GO:0048536	spleen development
0.65	GO:0001658	branching involved in ureteric bud morphogenesis
0.65	GO:0009954	proximal/distal pattern formation
0.65	GO:0048538	thymus development
0.65	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
0.64	GO:0035162	embryonic hemopoiesis
0.63	GO:0030326	embryonic limb morphogenesis
0.62	GO:0045665	negative regulation of neuron differentiation
0.62	GO:0048706	embryonic skeletal system development

0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.61	GO:0001012	RNA polymerase II regulatory region DNA binding
0.57	GO:0003690	double-stranded DNA binding
0.57	GO:0046982	protein heterodimerization activity
0.36	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.59	GO:0005667	transcription factor complex
0.54	GO:0031974	membrane-enclosed lumen
0.48	GO:0044446	intracellular organelle part
0.42	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|Q9I9C8|Q9I9C8_DANRE
SRY (sex determining region Y)-box 11a
Search

0.95	SRY-box containing protein 4

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.54	GO:0061386	closure of optic fissure
0.51	GO:0002088	lens development in camera-type eye
0.50	GO:0030182	neuron differentiation
0.50	GO:0007417	central nervous system development
0.49	GO:0072395	signal transduction involved in cell cycle checkpoint
0.48	GO:0060253	negative regulation of glial cell proliferation
0.48	GO:0048468	cell development

0.60	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.47	GO:0001105	RNA polymerase II transcription coactivator activity
0.45	GO:0001067	regulatory region nucleic acid binding
0.42	GO:0008135	translation factor activity, RNA binding
0.37	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.37	GO:0005667	transcription factor complex
0.36	GO:0005737	cytoplasm
0.36	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part

sp|Q9I9E1|FOXH1_DANRE
Forkhead box protein H1
Search

0.88	Forkhead box protein H1

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0006351	transcription, DNA-templated
0.46	GO:0009653	anatomical structure morphogenesis
0.46	GO:0030154	cell differentiation
0.44	GO:0007275	multicellular organism development
0.43	GO:0009888	tissue development
0.42	GO:0051253	negative regulation of RNA metabolic process
0.42	GO:0010558	negative regulation of macromolecule biosynthetic process

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.42	GO:0046332	SMAD binding
0.42	GO:0044212	transcription regulatory region DNA binding
0.40	GO:0003690	double-stranded DNA binding
0.37	GO:0001106	RNA polymerase II transcription corepressor activity
0.36	GO:0008134	transcription factor binding
0.35	GO:0019904	protein domain specific binding
0.34	GO:0051427	hormone receptor binding
0.33	GO:0004842	ubiquitin-protein transferase activity

0.61	GO:0005634	nucleus
0.36	GO:0005667	transcription factor complex
0.34	GO:0071797	LUBAC complex
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome
0.33	GO:0070013	intracellular organelle lumen

0.33

GO:0004842

tr|Q9I9E5|Q9I9E5_DANRE
Small nuclear ribonucleoprotein-associated protein
Search

SNRPB

0.85	Small nuclear ribonucleoprotein-associated proteins B and B'

0.50	GO:0000398	mRNA splicing, via spliceosome
0.44	GO:0022618	ribonucleoprotein complex assembly
0.42	GO:0008213	protein alkylation
0.41	GO:0043414	macromolecule methylation
0.37	GO:0009725	response to hormone
0.35	GO:0008334	histone mRNA metabolic process
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0007420	brain development
0.34	GO:0051170	nuclear import

0.56	GO:0003723	RNA binding
0.35	GO:1990447	U2 snRNP binding
0.35	GO:1990446	U1 snRNP binding
0.34	GO:0005515	protein binding

0.60	GO:0030529	intracellular ribonucleoprotein complex
0.58	GO:0005634	nucleus
0.57	GO:0019013	viral nucleocapsid
0.51	GO:0120114	Sm-like protein family complex
0.49	GO:0034709	methylosome
0.46	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.43	GO:0005829	cytosol
0.40	GO:0043234	protein complex
0.36	GO:0070062	extracellular exosome

tr|Q9I9E8|Q9I9E8_DANRE
E4tf1-60 transcription factor
Search

GABPA

0.97	GA binding protein transcription factor alpha subunit

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0045653	negative regulation of megakaryocyte differentiation
0.56	GO:0010468	regulation of gene expression
0.56	GO:1903351	cellular response to dopamine
0.49	GO:0006366	transcription by RNA polymerase II
0.49	GO:0001701	in utero embryonic development
0.48	GO:1902680	positive regulation of RNA biosynthetic process
0.47	GO:1902679	negative regulation of RNA biosynthetic process
0.43	GO:0030154	cell differentiation

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0033613	activating transcription factor binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003682	chromatin binding
0.48	GO:0046982	protein heterodimerization activity
0.48	GO:0003690	double-stranded DNA binding
0.34	GO:0003713	transcription coactivator activity

0.61	GO:0005634	nucleus
0.48	GO:0000785	chromatin
0.46	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

tr|Q9I9E9|Q9I9E9_DANRE
Eukaryotic translation initiation factor 2, subunit 1 alpha
Search

EIF2S1

0.87	Eukaryotic translation initiation factor 2 subunit alpha

0.72	GO:0006413	translational initiation
0.60	GO:0032057	negative regulation of translational initiation in response to stress
0.56	GO:0034198	cellular response to amino acid starvation
0.55	GO:0034644	cellular response to UV
0.55	GO:1901216	positive regulation of neuron death
0.54	GO:0034976	response to endoplasmic reticulum stress
0.53	GO:0046777	protein autophosphorylation
0.40	GO:2000676	positive regulation of type B pancreatic cell apoptotic process
0.40	GO:0071287	cellular response to manganese ion
0.40	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity

0.73	GO:0003743	translation initiation factor activity
0.52	GO:0043022	ribosome binding
0.36	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.59	GO:0005850	eukaryotic translation initiation factor 2 complex
0.58	GO:0005851	eukaryotic translation initiation factor 2B complex
0.54	GO:0010494	cytoplasmic stress granule
0.48	GO:0043614	multi-eIF complex
0.46	GO:0033290	eukaryotic 48S preinitiation complex
0.44	GO:0005634	nucleus
0.41	GO:0044207	translation initiation ternary complex
0.40	GO:0005840	ribosome
0.40	GO:0097451	glial limiting end-foot
0.36	GO:0070062	extracellular exosome

sp|Q9I9H8|APAF_DANRE
Apoptotic protease-activating factor 1
Search

APAF1

0.95	Apoptotic peptidase activating factor 1

0.76	GO:0097190	apoptotic signaling pathway
0.72	GO:0042981	regulation of apoptotic process
0.60	GO:1903624	regulation of DNA catabolic process
0.58	GO:2001056	positive regulation of cysteine-type endopeptidase activity
0.58	GO:0051402	neuron apoptotic process
0.57	GO:0001843	neural tube closure
0.55	GO:0043068	positive regulation of programmed cell death
0.55	GO:0030900	forebrain development
0.54	GO:0034976	response to endoplasmic reticulum stress
0.53	GO:0006508	proteolysis

0.74	GO:0043531	ADP binding
0.61	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.53	GO:0008233	peptidase activity
0.51	GO:0042802	identical protein binding
0.51	GO:0005524	ATP binding
0.37	GO:0031072	heat shock protein binding

0.84	GO:0043293	apoptosome
0.45	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.36	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen

0.53

GO:0008233

tr|Q9I9I2|Q9I9I2_DANRE
Protein Wnt
Search

sp|Q9I9K7|TBX20_DANRE
T-box transcription factor TBX20
Search

TBX20

0.83	T-box transcription factor TBX20

0.64	GO:0060577	pulmonary vein morphogenesis
0.64	GO:0035922	foramen ovale closure
0.63	GO:0036306	embryonic heart tube elongation
0.63	GO:0001947	heart looping
0.63	GO:0003180	aortic valve morphogenesis
0.63	GO:0003193	pulmonary valve formation
0.62	GO:0021524	visceral motor neuron differentiation
0.62	GO:0048738	cardiac muscle tissue development
0.62	GO:0060413	atrial septum morphogenesis
0.62	GO:0010991	negative regulation of SMAD protein complex assembly

0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0001105	RNA polymerase II transcription coactivator activity
0.58	GO:0001102	RNA polymerase II activating transcription factor binding
0.55	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q9I9L0|HEY2_DANRE
Hairy/enhancer-of-split related with YRPW motif protein 2
Search

HEY2

0.95	Hairy/enhancer-of-split related with YRPW motif protein 2

0.66	GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
0.63	GO:2000678	negative regulation of transcription regulatory region DNA binding
0.62	GO:0060842	arterial endothelial cell differentiation
0.62	GO:0045746	negative regulation of Notch signaling pathway
0.62	GO:0035912	dorsal aorta morphogenesis
0.62	GO:0007219	Notch signaling pathway
0.61	GO:0061027	umbilical cord development
0.61	GO:0003195	tricuspid valve formation
0.60	GO:0060948	cardiac vascular smooth muscle cell development
0.60	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation

0.68	GO:0046983	protein dimerization activity
0.66	GO:0035939	microsatellite binding
0.58	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding
0.56	GO:0001102	RNA polymerase II activating transcription factor binding
0.55	GO:0042826	histone deacetylase binding
0.55	GO:0000989	transcription factor activity, transcription factor binding
0.51	GO:0042802	identical protein binding
0.34	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.54	GO:0017053	transcriptional repressor complex
0.50	GO:0000785	chromatin
0.48	GO:0070013	intracellular organelle lumen
0.45	GO:1902494	catalytic complex
0.39	GO:0005737	cytoplasm
0.34	GO:0005667	transcription factor complex
0.30	GO:0031224	intrinsic component of membrane

tr|Q9I9N0|Q9I9N0_DANRE
Dap1b
Search

DAPL1

0.85	Death associated protein like 1

0.84	GO:0034198	cellular response to amino acid starvation
0.80	GO:0097190	apoptotic signaling pathway
0.74	GO:0010507	negative regulation of autophagy
0.47	GO:0006914	autophagy
0.46	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.46	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.44	GO:0030154	cell differentiation
0.42	GO:0045892	negative regulation of transcription, DNA-templated
0.38	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.38	GO:0007186	G-protein coupled receptor signaling pathway

0.85	GO:0070513	death domain binding
0.38	GO:0004984	olfactory receptor activity

0.30

GO:0016020

membrane

sp|Q9I9N5|TRADD_DANRE
Tumor necrosis factor receptor type 1-associated DEATH domain protein
Search

TRADD

0.85	Tnfrsf1a-associated via death domain

0.84	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.64	GO:0051798	positive regulation of hair follicle development
0.62	GO:0097191	extrinsic apoptotic signaling pathway
0.54	GO:0043065	positive regulation of apoptotic process

0.64	GO:0004871	signal transducer activity
0.64	GO:0070513	death domain binding
0.58	GO:0060090	molecular adaptor activity
0.57	GO:0019900	kinase binding
0.55	GO:0042802	identical protein binding

0.58	GO:0043235	receptor complex
0.45	GO:0005886	plasma membrane
0.41	GO:0005737	cytoplasm

sp|Q9I9N6|ASC_DANRE
Apoptosis-associated speck-like protein containing a CARD
Search

PYCARD

0.75	PYD and CARD domain containing

0.80	GO:0006954	inflammatory response
0.79	GO:0045087	innate immune response
0.74	GO:0042981	regulation of apoptotic process
0.56	GO:0097194	execution phase of apoptosis
0.55	GO:2001056	positive regulation of cysteine-type endopeptidase activity
0.54	GO:0050727	regulation of inflammatory response
0.53	GO:0043068	positive regulation of programmed cell death

0.61	GO:0032090	Pyrin domain binding
0.57	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis

0.59	GO:0072557	IPAF inflammasome complex
0.59	GO:0097169	AIM2 inflammasome complex
0.59	GO:0072559	NLRP3 inflammasome complex

sp|Q9I9P9|SMAD2_DANRE
Mothers against decapentaplegic homolog 2
Search

SMAD2

0.64	Mothers against decapentaplegic homolog

0.83	GO:0007179	transforming growth factor beta receptor signaling pathway
0.58	GO:1900224	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
0.58	GO:0006351	transcription, DNA-templated
0.58	GO:0007352	zygotic specification of dorsal/ventral axis
0.57	GO:0007182	common-partner SMAD protein phosphorylation
0.57	GO:0038092	nodal signaling pathway
0.57	GO:0007183	SMAD protein complex assembly
0.56	GO:0048340	paraxial mesoderm morphogenesis
0.56	GO:0070723	response to cholesterol
0.56	GO:0048617	embryonic foregut morphogenesis

0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
0.56	GO:0070410	co-SMAD binding
0.56	GO:0070878	primary miRNA binding
0.56	GO:0070411	I-SMAD binding
0.56	GO:0034713	type I transforming growth factor beta receptor binding
0.56	GO:0070412	R-SMAD binding
0.55	GO:0097718	disordered domain specific binding
0.55	GO:0003677	DNA binding
0.54	GO:0033613	activating transcription factor binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.56	GO:0071141	SMAD protein complex
0.49	GO:0005737	cytoplasm
0.48	GO:0000785	chromatin
0.46	GO:0070013	intracellular organelle lumen
0.35	GO:0097708	intracellular vesicle
0.30	GO:0016020	membrane

sp|Q9I9R3|S40A1_DANRE
Solute carrier family 40 member 1
Search

SLC40A1

0.94	Ferroportin

0.78	GO:0034755	iron ion transmembrane transport
0.53	GO:0060345	spleen trabecula formation
0.53	GO:1903414	iron cation export
0.53	GO:0070839	divalent metal ion export
0.52	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron
0.51	GO:0060586	multicellular organismal iron ion homeostasis
0.51	GO:0006879	cellular iron ion homeostasis
0.50	GO:0002260	lymphocyte homeostasis
0.49	GO:0003158	endothelium development
0.49	GO:0140115	export across plasma membrane

0.78	GO:0005381	iron ion transmembrane transporter activity
0.56	GO:0017046	peptide hormone binding
0.47	GO:0072509	divalent inorganic cation transmembrane transporter activity
0.45	GO:0005261	cation channel activity
0.45	GO:0042802	identical protein binding
0.42	GO:0004872	receptor activity

0.53	GO:0016323	basolateral plasma membrane
0.48	GO:0008021	synaptic vesicle
0.47	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.33	GO:0005887	integral component of plasma membrane

tr|Q9IAJ4|Q9IAJ4_DANRE
Mesoderm posterior aa
Search

0.97	BHLH transcription factor Mesp-a

0.63	GO:0001756	somitogenesis
0.59	GO:0009880	embryonic pattern specification
0.59	GO:0007498	mesoderm development
0.58	GO:0007379	segment specification
0.58	GO:0007369	gastrulation
0.56	GO:0048729	tissue morphogenesis
0.55	GO:0006366	transcription by RNA polymerase II
0.55	GO:0007507	heart development
0.55	GO:0045944	positive regulation of transcription by RNA polymerase II
0.53	GO:0009887	animal organ morphogenesis

0.68	GO:0046983	protein dimerization activity
0.58	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.55	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0003682	chromatin binding
0.43	GO:0035326	enhancer binding
0.34	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.32	GO:0004519	endonuclease activity

0.46	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome

sp|Q9IAK8|TBX5A_DANRE
T-box transcription factor TBX5-A
Search

TBX5

0.97	Regeneration blastema forelimb-specific Tbx

0.63	GO:0035108	limb morphogenesis
0.63	GO:0035113	embryonic appendage morphogenesis
0.60	GO:0060039	pericardium development
0.59	GO:0002009	morphogenesis of an epithelium
0.59	GO:0030324	lung development
0.58	GO:0051891	positive regulation of cardioblast differentiation
0.58	GO:0006351	transcription, DNA-templated
0.58	GO:0003181	atrioventricular valve morphogenesis
0.58	GO:0009887	animal organ morphogenesis
0.58	GO:0060044	negative regulation of cardiac muscle cell proliferation

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.51	GO:0008134	transcription factor binding
0.51	GO:0001067	regulatory region nucleic acid binding
0.38	GO:0030274	LIM domain binding
0.37	GO:0097110	scaffold protein binding
0.36	GO:0051087	chaperone binding

0.61	GO:0005634	nucleus
0.49	GO:0032993	protein-DNA complex
0.42	GO:0015629	actin cytoskeleton
0.39	GO:0005737	cytoplasm
0.36	GO:0099513	polymeric cytoskeletal fiber
0.34	GO:0005667	transcription factor complex
0.33	GO:0070013	intracellular organelle lumen
0.30	GO:0016020	membrane

tr|Q9IAT0|Q9IAT0_DANRE
Zic family member 2 (Odd-paired homolog, Drosophila), a
Search

0.96	Zinc finger protein ZIC 2-A

0.55	GO:0007417	central nervous system development
0.55	GO:0060322	head development
0.52	GO:0048513	animal organ development
0.49	GO:0048385	regulation of retinoic acid receptor signaling pathway
0.48	GO:0048598	embryonic morphogenesis
0.47	GO:0048864	stem cell development
0.47	GO:0008589	regulation of smoothened signaling pathway
0.47	GO:1904888	cranial skeletal system development
0.47	GO:0048706	embryonic skeletal system development
0.45	GO:0007389	pattern specification process

0.50	GO:0003676	nucleic acid binding
0.44	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0003682	chromatin binding
0.34	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.46	GO:0005634	nucleus
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm

sp|Q9IAT6|DLLC_DANRE
Delta-like protein C
Search

0.72	Delta-like protein 1

0.76	GO:0021688	cerebellar molecular layer formation
0.76	GO:0097102	endothelial tip cell fate specification
0.76	GO:0060853	Notch signaling pathway involved in arterial endothelial cell fate commitment
0.74	GO:0045608	negative regulation of inner ear auditory receptor cell differentiation
0.74	GO:0021693	cerebellar Purkinje cell layer structural organization
0.74	GO:0048633	positive regulation of skeletal muscle tissue growth
0.74	GO:0048630	skeletal muscle tissue growth
0.74	GO:0046331	lateral inhibition
0.73	GO:0007386	compartment pattern specification
0.73	GO:0002315	marginal zone B cell differentiation

0.73	GO:0030957	Tat protein binding
0.70	GO:0005509	calcium ion binding
0.70	GO:0097110	scaffold protein binding
0.70	GO:0005112	Notch binding

0.66	GO:0016324	apical plasma membrane
0.65	GO:0098857	membrane microdomain
0.64	GO:0005912	adherens junction
0.59	GO:0031410	cytoplasmic vesicle
0.45	GO:0005887	integral component of plasma membrane
0.45	GO:0005576	extracellular region
0.43	GO:0005634	nucleus

sp|Q9IAV3|HHEX_DANRE
Hematopoietically-expressed homeobox protein hhex
Search

HHEX

0.97	Hematopoietically-expressed homeobox protein hhex

0.59	GO:0061011	hepatic duct development
0.59	GO:0060431	primary lung bud formation
0.59	GO:0061017	hepatoblast differentiation
0.59	GO:0061010	gall bladder development
0.58	GO:0022027	interkinetic nuclear migration
0.58	GO:0070365	hepatocyte differentiation
0.58	GO:0090009	primitive streak formation
0.57	GO:0030878	thyroid gland development
0.57	GO:0048853	forebrain morphogenesis
0.57	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway

0.63	GO:0043565	sequence-specific DNA binding
0.57	GO:0071837	HMG box domain binding
0.57	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.56	GO:0008190	eukaryotic initiation factor 4E binding
0.55	GO:0008301	DNA binding, bending
0.55	GO:0070491	repressing transcription factor binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.51	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.49	GO:0032993	protein-DNA complex
0.39	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle

sp|Q9IB61|BLCAP_DANRE
Bladder cancer-associated protein
Search

BLCAP

0.97	Bladder cancer-associated protein (Fragment)

0.55	GO:0030262	apoptotic nuclear changes
0.38	GO:0007049	cell cycle

0.33

GO:0005515

protein binding

0.30

GO:0044425

membrane part

tr|Q9IB77|Q9IB77_DANRE
Anti-proliferative cofactor
Search

BTG2

0.94	Anti-proliferative cofactor

0.79	GO:0008285	negative regulation of cell proliferation
0.52	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.52	GO:2000271	positive regulation of fibroblast apoptotic process
0.52	GO:0021542	dentate gyrus development
0.51	GO:0045603	positive regulation of endothelial cell differentiation
0.51	GO:0045663	positive regulation of myoblast differentiation
0.51	GO:0035914	skeletal muscle cell differentiation
0.50	GO:0008306	associative learning
0.50	GO:0021954	central nervous system neuron development
0.50	GO:2000177	regulation of neural precursor cell proliferation

0.45	GO:0019899	enzyme binding
0.38	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0003712	transcription cofactor activity

0.41	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.35	GO:0070062	extracellular exosome

tr|Q9IB88|Q9IB88_DANRE
VAL-opsin
Search

0.97	Vertebrate ancient long opsin b

0.74	GO:0007602	phototransduction
0.73	GO:0007601	visual perception
0.72	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.51	GO:0009584	detection of visible light
0.48	GO:0016038	absorption of visible light
0.47	GO:0071482	cellular response to light stimulus

0.77	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.49	GO:0043005	neuron projection
0.49	GO:0043204	perikaryon
0.44	GO:0097731	9+0 non-motile cilium
0.43	GO:0044441	ciliary part
0.37	GO:0042599	lamellar body
0.35	GO:0005815	microtubule organizing center
0.34	GO:0030667	secretory granule membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q9IBD0|CELF1_DANRE
CUGBP Elav-like family member 1
Search

0.95	CUG-BP-and ETR-3-like factor 1

0.48	GO:0040018	positive regulation of multicellular organism growth
0.48	GO:0006376	mRNA splice site selection
0.47	GO:0007286	spermatid development
0.39	GO:1990402	embryonic liver development
0.39	GO:0061113	pancreas morphogenesis
0.39	GO:0061031	endodermal digestive tract morphogenesis
0.38	GO:0061014	positive regulation of mRNA catabolic process
0.38	GO:0001889	liver development
0.38	GO:0048588	developmental cell growth
0.38	GO:0007368	determination of left/right symmetry

0.59	GO:0003723	RNA binding
0.47	GO:0031369	translation initiation factor binding
0.34	GO:0000900	translation repressor activity, nucleic acid binding

0.43	GO:0005654	nucleoplasm
0.38	GO:0045495	pole plasm
0.32	GO:1990904	ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q9IBD1|CELF3_DANRE
CUGBP Elav-like family member 3
Search

CELF3

0.92	Trinucleotide repeat containing 4 (Predicted)

0.51	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.50	GO:0030575	nuclear body organization
0.49	GO:0030317	flagellated sperm motility
0.49	GO:0098781	ncRNA transcription
0.48	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.47	GO:0007283	spermatogenesis
0.45	GO:0008380	RNA splicing
0.38	GO:0006397	mRNA processing
0.34	GO:0071625	vocalization behavior
0.33	GO:0001505	regulation of neurotransmitter levels

0.59

GO:0003723

RNA binding

0.47	GO:0016604	nuclear body
0.37	GO:0005737	cytoplasm

tr|Q9IBH3|Q9IBH3_DANRE
F-box and WD repeat domain-containing 4
Search

FBXW4

0.97	F-box and WD repeat domain-containing 4

0.84	GO:0002053	positive regulation of mesenchymal cell proliferation
0.82	GO:0042733	embryonic digit morphogenesis
0.79	GO:0051216	cartilage development
0.66	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.43	GO:0016567	protein ubiquitination
0.42	GO:0016055	Wnt signaling pathway
0.39	GO:0043687	post-translational protein modification

0.43	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0005515	protein binding

0.65	GO:0019005	SCF ubiquitin ligase complex
0.37	GO:0005829	cytosol

0.43

GO:0004842

sp|Q9MIX8|CYB_DANRE
Cytochrome b
Search

CYTB

0.41	Cytochrome b

0.72

GO:0006122

mitochondrial electron transport, ubiquinol to cytochrome c

0.72	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.62	GO:0009055	electron transfer activity
0.54	GO:0046872	metal ion binding

0.71	GO:0045275	respiratory chain complex III
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.72

EC:1.10.2

GO:0016681

sp|Q9MIX9|NU6M_DANRE
NADH-ubiquinone oxidoreductase chain 6
Search

ND6

0.50	NADH-ubiquinone oxidoreductase chain 6

0.53

GO:0055114

oxidation-reduction process

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.34	GO:0070469	respiratory chain
0.34	GO:0031967	organelle envelope
0.34	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|Q9MIY0|NU5M_DANRE
NADH-ubiquinone oxidoreductase chain 5
Search

ND5

0.45	NADH-ubiquinone oxidoreductase chain 5

0.68

GO:0042773

ATP synthesis coupled electron transport

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.61	GO:0070469	respiratory chain
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|Q9MIY1|NU4M_DANRE
NADH-ubiquinone oxidoreductase chain 4
Search

ND4

0.45	NADH-ubiquinone oxidoreductase chain 4

0.74

GO:0006120

mitochondrial electron transport, NADH to ubiquinone

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.34	GO:0070469	respiratory chain
0.34	GO:0031967	organelle envelope
0.34	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|Q9MIY2|NU4LM_DANRE
NADH-ubiquinone oxidoreductase chain 4L
Search

ND4L

0.50	NADH-ubiquinone oxidoreductase chain 4L

0.69

GO:0042773

ATP synthesis coupled electron transport

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.35	GO:0045271	respiratory chain complex I
0.34	GO:1990204	oxidoreductase complex
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0008137

sp|Q9MIY3|NU3M_DANRE
NADH-ubiquinone oxidoreductase chain 3
Search

ND3

0.47	NADH-ubiquinone oxidoreductase chain 3

0.53

GO:0055114

oxidation-reduction process

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.34	GO:0030964	NADH dehydrogenase complex
0.34	GO:0098798	mitochondrial protein complex
0.33	GO:1990204	oxidoreductase complex
0.33	GO:0098796	membrane protein complex
0.33	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|Q9MIY4|COX3_DANRE
Cytochrome c oxidase subunit 3
Search

COX3

0.45	Cytochrome c oxidase subunit 3

0.76	GO:0019646	aerobic electron transport chain
0.63	GO:1902600	hydrogen ion transmembrane transport

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.61	GO:0005739	mitochondrion
0.34	GO:0045277	respiratory chain complex IV
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.65

EC:1.9.3

GO:0016676

sp|Q9MIY5|ATP6_DANRE
ATP synthase subunit a
Search

ATP6

0.42	ATP synthase subunit a

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process

0.63

GO:0015078

hydrogen ion transmembrane transporter activity

0.72	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

sp|Q9MIY6|ATP8_DANRE
ATP synthase protein 8
Search

ATPASE 8

0.48	ATP synthase protein 8

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.69	GO:0006754	ATP biosynthetic process

0.62

GO:0015078

hydrogen ion transmembrane transporter activity

0.77	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.30	GO:0016021	integral component of membrane

sp|Q9MIY7|COX2_DANRE
Cytochrome c oxidase subunit 2
Search

COII

0.43	Cytochrome c oxidase subunit 2

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.33	GO:0006119	oxidative phosphorylation
0.33	GO:0045333	cellular respiration

0.72	GO:0005507	copper ion binding
0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.34	GO:0070069	cytochrome complex
0.34	GO:0098798	mitochondrial protein complex
0.34	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.65

EC:1.9.3

GO:0016676

sp|Q9MIY8|COX1_DANRE
Cytochrome c oxidase subunit 1
Search

COI

0.26	Cytochrome c oxidase subunit 1

0.64	GO:0006119	oxidative phosphorylation
0.64	GO:0009060	aerobic respiration
0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.36	GO:0051597	response to methylmercury
0.35	GO:0046686	response to cadmium ion

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0020037	heme binding
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.63	GO:0005506	iron ion binding
0.62	GO:0009055	electron transfer activity

0.65	GO:0045277	respiratory chain complex IV
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.34	GO:0098798	mitochondrial protein complex
0.30	GO:0016021	integral component of membrane

0.65

EC:1.9.3

GO:0016676

sp|Q9MIY9|NU2M_DANRE
NADH-ubiquinone oxidoreductase chain 2
Search

ND2

0.44	NADH-ubiquinone oxidoreductase chain 2

0.75

GO:0006120

mitochondrial electron transport, NADH to ubiquinone

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|Q9MIZ0|NU1M_DANRE
NADH-ubiquinone oxidoreductase chain 1
Search

ND1

0.47	NADH-ubiquinone oxidoreductase chain 1

0.53	GO:0055114	oxidation-reduction process
0.33	GO:0006091	generation of precursor metabolites and energy

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.34	GO:0045271	respiratory chain complex I
0.34	GO:0098798	mitochondrial protein complex
0.34	GO:1990204	oxidoreductase complex
0.30	GO:0031224	intrinsic component of membrane

0.69