Queries 22001 to 23000

GO:0016787

sp|Q6NY52|THOC5_DANRE
THO complex subunit 5 homolog
Search

THOC5

0.95	THO complex subunit 5

0.82	GO:0046784	viral mRNA export from host cell nucleus
0.82	GO:2000002	negative regulation of DNA damage checkpoint
0.81	GO:0030224	monocyte differentiation
0.78	GO:0032786	positive regulation of DNA-templated transcription, elongation
0.78	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.75	GO:0051028	mRNA transport
0.73	GO:0006405	RNA export from nucleus
0.53	GO:0010467	gene expression
0.49	GO:0060215	primitive hemopoiesis
0.49	GO:0016071	mRNA metabolic process

0.58	GO:0003729	mRNA binding
0.38	GO:0005515	protein binding

0.82	GO:0000445	THO complex part of transcription export complex
0.73	GO:0000784	nuclear chromosome, telomeric region
0.66	GO:0005654	nucleoplasm
0.40	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q6NY62|Q6NY62_DANRE
Forkhead box I2
Search

FOXI1

0.95	Forkhead transcription factor i2

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0042472	inner ear morphogenesis
0.55	GO:0010468	regulation of gene expression
0.50	GO:1902680	positive regulation of RNA biosynthetic process
0.50	GO:0006366	transcription by RNA polymerase II
0.49	GO:0030154	cell differentiation
0.46	GO:0048890	lateral line ganglion development
0.45	GO:0008544	epidermis development
0.44	GO:0060788	ectodermal placode formation

0.63	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.35	GO:0008301	DNA binding, bending

0.60	GO:0005634	nucleus
0.46	GO:0043233	organelle lumen
0.43	GO:0043232	intracellular non-membrane-bounded organelle
0.42	GO:0044446	intracellular organelle part

sp|Q6NY64|2ABD_DANRE
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
Search

PPP2R2D

0.65	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B

0.79	GO:0043666	regulation of phosphoprotein phosphatase activity
0.49	GO:0070262	peptidyl-serine dephosphorylation
0.47	GO:0043278	response to morphine
0.45	GO:0000278	mitotic cell cycle
0.43	GO:0032502	developmental process
0.40	GO:0044770	cell cycle phase transition
0.39	GO:0000280	nuclear division
0.38	GO:0051301	cell division
0.33	GO:0032501	multicellular organismal process

0.80	GO:0019888	protein phosphatase regulator activity
0.48	GO:0004722	protein serine/threonine phosphatase activity
0.37	GO:0048156	tau protein binding
0.36	GO:0051721	protein phosphatase 2A binding
0.35	GO:0032403	protein complex binding
0.35	GO:0008195	phosphatidate phosphatase activity

0.81	GO:0000159	protein phosphatase type 2A complex
0.43	GO:0005829	cytosol
0.35	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:3.1.3.4

GO:0008195

tr|Q6NY65|Q6NY65_DANRE
Regulator of chromosome condensation 1
Search

tr|Q6NY69|Q6NY69_DANRE
Ubiquitin-like 3a
Search

UBL3

0.74	Ubiquitin-like protein 3

0.66	GO:0070062	extracellular exosome
0.56	GO:0005886	plasma membrane
0.43	GO:0005622	intracellular

sp|Q6NY73|L3BPB_DANRE
Galectin-3-binding protein B
Search

0.76	Galectin-3-binding protein B

0.72	GO:0006898	receptor-mediated endocytosis
0.47	GO:0070207	protein homotrimerization
0.46	GO:0034755	iron ion transmembrane transport
0.45	GO:0006879	cellular iron ion homeostasis
0.45	GO:0034605	cellular response to heat
0.41	GO:0007155	cell adhesion
0.35	GO:0006952	defense response
0.34	GO:0002376	immune system process
0.34	GO:0009617	response to bacterium
0.34	GO:1900017	positive regulation of cytokine production involved in inflammatory response

0.81	GO:0005044	scavenger receptor activity
0.51	GO:0070287	ferritin receptor activity
0.34	GO:0035375	zymogen binding
0.34	GO:0070891	lipoteichoic acid binding
0.33	GO:0001530	lipopolysaccharide binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0042802	identical protein binding
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0008233	peptidase activity

0.43	GO:0009986	cell surface
0.42	GO:0031226	intrinsic component of plasma membrane
0.42	GO:0005578	proteinaceous extracellular matrix
0.35	GO:0031982	vesicle
0.35	GO:0072562	blood microparticle
0.34	GO:0043230	extracellular organelle
0.34	GO:0042101	T cell receptor complex
0.34	GO:0001772	immunological synapse
0.33	GO:0019898	extrinsic component of membrane
0.33	GO:0031090	organelle membrane

0.32

GO:0008233

sp|Q6NY74|RFA1_DANRE
Replication protein A 70 kDa DNA-binding subunit
Search

RPA1

0.69	Replication protein A subunit

0.66	GO:0006260	DNA replication
0.65	GO:0006310	DNA recombination
0.65	GO:0006281	DNA repair
0.53	GO:0034502	protein localization to chromosome
0.49	GO:0000723	telomere maintenance
0.43	GO:0007507	heart development
0.37	GO:0048873	homeostasis of number of cells within a tissue
0.36	GO:0001701	in utero embryonic development
0.36	GO:0030097	hemopoiesis
0.36	GO:0008284	positive regulation of cell proliferation

0.55	GO:0003677	DNA binding
0.54	GO:0046872	metal ion binding
0.36	GO:0003682	chromatin binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.49	GO:0030894	replisome
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0043234	protein complex
0.36	GO:0000781	chromosome, telomeric region
0.35	GO:0000793	condensed chromosome

sp|Q6NY77|HOGA1_DANRE
4-hydroxy-2-oxoglutarate aldolase, mitochondrial
Search

HOGA1

0.59	N-acetylneuraminate lyase

0.57	GO:0019470	4-hydroxyproline catabolic process
0.53	GO:0009436	glyoxylate catabolic process
0.52	GO:0042866	pyruvate biosynthetic process
0.52	GO:0033609	oxalate metabolic process
0.33	GO:0015711	organic anion transport
0.32	GO:0055085	transmembrane transport

0.62	GO:0016829	lyase activity
0.49	GO:0042803	protein homodimerization activity
0.33	GO:0008514	organic anion transmembrane transporter activity

0.44	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0005887	integral component of plasma membrane
0.33	GO:0044446	intracellular organelle part

0.62

EC:4

GO:0016829

tr|Q6NY81|Q6NY81_DANRE
EH-domain-containing 1a
Search

EHD1

0.87	EH domain-containing protein 1

0.57	GO:0060271	cilium assembly
0.52	GO:0016197	endosomal transport
0.52	GO:0051050	positive regulation of transport
0.50	GO:2001135	regulation of endocytic recycling
0.50	GO:0010886	positive regulation of cholesterol storage
0.50	GO:1901741	positive regulation of myoblast fusion
0.50	GO:0034383	low-density lipoprotein particle clearance
0.49	GO:0086036	regulation of cardiac muscle cell membrane potential
0.49	GO:0090160	Golgi to lysosome transport
0.49	GO:1903358	regulation of Golgi organization

0.69	GO:0005509	calcium ion binding
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0045296	cadherin binding
0.37	GO:0017137	Rab GTPase binding
0.36	GO:0042802	identical protein binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0008144	drug binding

0.53	GO:0043209	myelin sheath
0.52	GO:0030139	endocytic vesicle
0.52	GO:0020018	ciliary pocket membrane
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0031095	platelet dense tubular network membrane
0.51	GO:0005768	endosome
0.47	GO:0005811	lipid droplet
0.46	GO:0044433	cytoplasmic vesicle part
0.45	GO:0098805	whole membrane
0.42	GO:0005829	cytosol

sp|Q6NY82|UBE2F_DANRE
NEDD8-conjugating enzyme UBE2F
Search

UBE2F

0.80	UBE2F-SCLY readthrough (NMD candidate)

0.50	GO:0045116	protein neddylation
0.45	GO:0016567	protein ubiquitination
0.35	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.34	GO:0043687	post-translational protein modification
0.33	GO:0006886	intracellular protein transport

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0019788	NEDD8 transferase activity
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0061630	ubiquitin protein ligase activity
0.35	GO:0016874	ligase activity
0.34	GO:0008565	protein transporter activity

0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.35

GO:0016874

tr|Q6NY87|Q6NY87_DANRE
Excision repair cross-complementation group 1
Search

ERCC1

0.88	Excision repair cross-complementing rodent repair deficiency, complementation group 1

0.63	GO:0006281	DNA repair
0.62	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.57	GO:1904431	positive regulation of t-circle formation
0.57	GO:0006312	mitotic recombination
0.56	GO:0090737	telomere maintenance via telomere trimming
0.56	GO:0001325	formation of extrachromosomal circular DNA
0.56	GO:1905764	regulation of protection from non-homologous end joining at telomere
0.56	GO:1904506	negative regulation of telomere maintenance in response to DNA damage
0.55	GO:1904354	negative regulation of telomere capping
0.55	GO:0009650	UV protection

0.71	GO:0003684	damaged DNA binding
0.64	GO:0004519	endonuclease activity
0.56	GO:0001094	TFIID-class transcription factor binding
0.53	GO:0008022	protein C-terminus binding
0.51	GO:0003697	single-stranded DNA binding
0.50	GO:0004536	deoxyribonuclease activity
0.49	GO:0019904	protein domain specific binding
0.35	GO:0017025	TBP-class protein binding
0.35	GO:0031593	polyubiquitin modification-dependent protein binding
0.33	GO:0003735	structural constituent of ribosome

0.60	GO:0005634	nucleus
0.52	GO:1990391	DNA repair complex
0.51	GO:0000781	chromosome, telomeric region
0.49	GO:0000428	DNA-directed RNA polymerase complex
0.49	GO:0005667	transcription factor complex
0.47	GO:0070013	intracellular organelle lumen
0.47	GO:0005829	cytosol
0.34	GO:0035861	site of double-strand break
0.33	GO:0005840	ribosome

0.33

EC:3.6.1.15

GO:0017111

sp|Q6NY88|CHMP3_DANRE
Charged multivesicular body protein 3
Search

CHMP3

0.83	Charged multivesicular body protein 3

0.78	GO:0007034	vacuolar transport
0.43	GO:2000641	regulation of early endosome to late endosome transport
0.43	GO:1902188	positive regulation of viral release from host cell
0.42	GO:1902187	negative regulation of viral release from host cell
0.42	GO:0000920	cell separation after cytokinesis
0.42	GO:0051291	protein heterooligomerization
0.42	GO:0010824	regulation of centrosome duplication
0.41	GO:0090174	organelle membrane fusion
0.41	GO:0032509	endosome transport via multivesicular body sorting pathway
0.40	GO:0039702	viral budding via host ESCRT complex

0.43	GO:1990381	ubiquitin-specific protease binding
0.42	GO:0031210	phosphatidylcholine binding
0.40	GO:0042803	protein homodimerization activity
0.36	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.33	GO:0016874	ligase activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0016787	hydrolase activity

0.44	GO:0005770	late endosome
0.44	GO:0010008	endosome membrane
0.41	GO:0036452	ESCRT complex
0.39	GO:0005829	cytosol
0.37	GO:0098796	membrane protein complex
0.36	GO:0030496	midbody
0.36	GO:0070062	extracellular exosome
0.36	GO:0005769	early endosome
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

GO:0016874

sp|Q6NY89|LSG1_DANRE
Large subunit GTPase 1 homolog
Search

LSG1

0.90	Large subunit GTPase

0.52	GO:0051168	nuclear export
0.43	GO:0042254	ribosome biogenesis
0.38	GO:0015031	protein transport
0.32	GO:0006518	peptide metabolic process
0.32	GO:0043604	amide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:1901566	organonitrogen compound biosynthetic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.64	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0003924	GTPase activity
0.33	GO:0003735	structural constituent of ribosome

0.57	GO:0015030	Cajal body
0.50	GO:0005783	endoplasmic reticulum
0.49	GO:0005829	cytosol
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

tr|Q6NY93|Q6NY93_DANRE
Fucosidase, alpha-L- 1, tissue, tandem duplicate 1
Search

FUCA1

0.89	Tissue alpha-L-fucosidase

0.79	GO:0006004	fucose metabolic process
0.55	GO:0016139	glycoside catabolic process
0.36	GO:2000535	regulation of entry of bacterium into host cell
0.36	GO:0019377	glycolipid catabolic process
0.35	GO:0009617	response to bacterium
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0006027	glycosaminoglycan catabolic process

0.80	GO:0004560	alpha-L-fucosidase activity
0.33	GO:0030246	carbohydrate binding
0.32	GO:0003676	nucleic acid binding

0.39	GO:0005764	lysosome
0.37	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:0034774	secretory granule lumen
0.35	GO:0005775	vacuolar lumen
0.30	GO:0016020	membrane

0.80

EC:3.2.1.51

GO:0004560

sp|Q6NY98|MCE1_DANRE
mRNA-capping enzyme
Search

RNGTT

0.86	mRNA-capping enzyme

0.83	GO:0098507	polynucleotide 5' dephosphorylation
0.75	GO:0006370	7-methylguanosine mRNA capping
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.34	GO:0006366	transcription by RNA polymerase II
0.33	GO:0007018	microtubule-based movement
0.33	GO:0016032	viral process

0.84	GO:0004484	mRNA guanylyltransferase activity
0.83	GO:0004651	polynucleotide 5'-phosphatase activity
0.78	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.60	GO:0032550	purine ribonucleoside binding
0.60	GO:0019001	guanyl nucleotide binding
0.58	GO:0050355	triphosphatase activity
0.50	GO:0032555	purine ribonucleotide binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0016459	myosin complex
0.30	GO:0031224	intrinsic component of membrane

0.84	EC:2.7.7.50	GO:0004484
0.58	KEGG:R00138	GO:0050355

sp|Q6NYA0|SRS1B_DANRE
Serine/arginine-rich splicing factor 1B
Search

SRSF1

0.94	Serine and arginine rich splicing factor 1

0.52	GO:0000395	mRNA 5'-splice site recognition
0.52	GO:0000380	alternative mRNA splicing, via spliceosome
0.51	GO:0060048	cardiac muscle contraction
0.48	GO:0001701	in utero embryonic development
0.38	GO:0097421	liver regeneration
0.38	GO:0033120	positive regulation of RNA splicing
0.38	GO:0048709	oligodendrocyte differentiation
0.37	GO:0051028	mRNA transport
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus

0.59	GO:0003723	RNA binding
0.54	GO:0050733	RS domain binding
0.53	GO:0044547	DNA topoisomerase binding
0.38	GO:0043422	protein kinase B binding

0.51	GO:0035145	exon-exon junction complex
0.51	GO:0016607	nuclear speck
0.49	GO:0071013	catalytic step 2 spliceosome
0.36	GO:0070062	extracellular exosome
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q6NYA1|Q6NYA1_DANRE
Heterogeneous nuclear ribonucleoprotein A/Bb
Search

HNRNPAB

0.96	Heterogeneous nuclear ribonucleoprotein A/Bb

0.39	GO:0001837	epithelial to mesenchymal transition
0.38	GO:1904580	regulation of intracellular mRNA localization
0.37	GO:0045893	positive regulation of transcription, DNA-templated
0.37	GO:0000122	negative regulation of transcription by RNA polymerase II
0.37	GO:0071230	cellular response to amino acid stimulus
0.32	GO:0006351	transcription, DNA-templated

0.59	GO:0003723	RNA binding
0.36	GO:0005515	protein binding
0.36	GO:1990837	sequence-specific double-stranded DNA binding
0.35	GO:0044877	macromolecular complex binding
0.35	GO:0003700	DNA binding transcription factor activity

0.62	GO:0019013	viral nucleocapsid
0.56	GO:0030529	intracellular ribonucleoprotein complex
0.45	GO:0005654	nucleoplasm
0.38	GO:0090575	RNA polymerase II transcription factor complex
0.37	GO:0120111	neuron projection cytoplasm
0.36	GO:0030425	dendrite
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q6NYB4|MB211_DANRE
Putative nucleotidyltransferase MAB21L1
Search

MAB21L1

0.96	Mab-21 like 1

0.81	GO:0043010	camera-type eye development
0.79	GO:0008284	positive regulation of cell proliferation
0.42	GO:0010172	embryonic body morphogenesis

0.61	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm

sp|Q6NYD1|ROMO1_DANRE
Reactive oxygen species modulator 1
Search

ROMO1

0.97	Reactive oxygen species modulator 1

0.54	GO:2000379	positive regulation of reactive oxygen species metabolic process
0.54	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.54	GO:0001302	replicative cell aging
0.52	GO:0050830	defense response to Gram-positive bacterium
0.52	GO:0050829	defense response to Gram-negative bacterium
0.51	GO:0051715	cytolysis in other organism
0.51	GO:0008284	positive regulation of cell proliferation
0.50	GO:0034614	cellular response to reactive oxygen species
0.42	GO:1903146	regulation of autophagy of mitochondrion

0.43	GO:0005739	mitochondrion
0.37	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

tr|Q6NYD2|Q6NYD2_DANRE
Sideroflexin
Search

SFXN2

0.81	Sideroflexin

0.60	GO:0034220	ion transmembrane transport
0.36	GO:0055072	iron ion homeostasis

0.60

GO:0015075

ion transmembrane transporter activity

0.59	GO:0031966	mitochondrial membrane
0.43	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q6NYD4|MAK16_DANRE
Protein MAK16 homolog
Search

0.10	Putative rna-binding nuclear protein mak16 (Fragment)

0.48	GO:0000470	maturation of LSU-rRNA
0.48	GO:0000460	maturation of 5.8S rRNA
0.34	GO:0007275	multicellular organism development

0.34	GO:0003723	RNA binding
0.33	GO:0008270	zinc ion binding

0.69	GO:0005730	nucleolus
0.48	GO:0030687	preribosome, large subunit precursor
0.35	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q6NYD7|OCAD1_DANRE
OCIA domain-containing protein 1
Search

OCIAD1

0.93	OCIA domain-containing protein 1

0.77

GO:2000736

regulation of stem cell differentiation

0.38

GO:0005515

protein binding

0.72	GO:0005768	endosome
0.55	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

tr|Q6NYD8|Q6NYD8_DANRE
ADP-ribosylation factor 2
Search

ARF1

0.77	ADP-ribosylation factor 1

0.54	GO:1990386	mitotic cleavage furrow ingression
0.49	GO:0098586	cellular response to virus
0.49	GO:0016192	vesicle-mediated transport
0.48	GO:0006878	cellular copper ion homeostasis
0.41	GO:0060292	long term synaptic depression
0.41	GO:0097061	dendritic spine organization
0.40	GO:0002090	regulation of receptor internalization
0.40	GO:1903337	positive regulation of vacuolar transport
0.40	GO:0015031	protein transport
0.40	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation

0.66	GO:0005525	GTP binding
0.47	GO:0019904	protein domain specific binding
0.46	GO:0046982	protein heterodimerization activity
0.43	GO:0000287	magnesium ion binding
0.40	GO:1990583	phospholipase D activator activity
0.38	GO:0019003	GDP binding
0.34	GO:0003924	GTPase activity
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0005102	receptor binding
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.52	GO:0005794	Golgi apparatus
0.48	GO:0030017	sarcomere
0.48	GO:0031252	cell leading edge
0.44	GO:0005829	cytosol
0.41	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0043234	protein complex
0.40	GO:0070062	extracellular exosome
0.39	GO:0014069	postsynaptic density
0.38	GO:0045211	postsynaptic membrane
0.38	GO:0043005	neuron projection

0.33

GO:0003755

tr|Q6NYE1|Q6NYE1_DANRE
Fibrinogen beta chain
Search

FGB

0.73	Fibrinogen B-beta subunit

0.83	GO:0030168	platelet activation
0.76	GO:0051258	protein polymerization
0.61	GO:0072378	blood coagulation, fibrin clot formation
0.60	GO:0007165	signal transduction
0.59	GO:0043152	induction of bacterial agglutination
0.58	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.58	GO:0042730	fibrinolysis
0.57	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.57	GO:0045907	positive regulation of vasoconstriction
0.57	GO:2000352	negative regulation of endothelial cell apoptotic process

0.79	GO:0030674	protein binding, bridging
0.71	GO:0005102	receptor binding
0.53	GO:0050839	cell adhesion molecule binding
0.52	GO:0051087	chaperone binding
0.45	GO:0005198	structural molecule activity
0.32	GO:0046872	metal ion binding

0.85	GO:0005577	fibrinogen complex
0.57	GO:0031091	platelet alpha granule
0.54	GO:0009897	external side of plasma membrane
0.52	GO:0005938	cell cortex
0.49	GO:0005783	endoplasmic reticulum
0.40	GO:0072562	blood microparticle
0.36	GO:0070062	extracellular exosome
0.35	GO:0034774	secretory granule lumen

sp|Q6NYE2|RCC2_DANRE
Protein RCC2 homolog
Search

0.82	GO:0072356	chromosome passenger complex localization to kinetochore
0.78	GO:0048041	focal adhesion assembly
0.77	GO:0034260	negative regulation of GTPase activity
0.77	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading
0.77	GO:0051895	negative regulation of focal adhesion assembly
0.77	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore
0.76	GO:0010762	regulation of fibroblast migration
0.76	GO:1900027	regulation of ruffle assembly
0.75	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
0.73	GO:0090630	activation of GTPase activity

0.76	GO:0048365	Rac GTPase binding
0.69	GO:0019901	protein kinase binding
0.67	GO:0019904	protein domain specific binding
0.65	GO:0008017	microtubule binding
0.36	GO:0003723	RNA binding
0.35	GO:0003677	DNA binding

0.76	GO:0034506	chromosome, centromeric core domain
0.74	GO:1990023	mitotic spindle midzone
0.73	GO:0031901	early endosome membrane
0.72	GO:0030496	midbody
0.56	GO:0005634	nucleus
0.50	GO:0005886	plasma membrane
0.41	GO:0031974	membrane-enclosed lumen
0.39	GO:0005874	microtubule
0.36	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|Q6NYE3|Q6NYE3_DANRE
Phosphoglucomutase 2
Search

PGM2

0.89	Phosphoglucomutase 2

0.60	GO:0005975	carbohydrate metabolic process
0.40	GO:0044281	small molecule metabolic process
0.37	GO:0046386	deoxyribose phosphate catabolic process
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0006112	energy reserve metabolic process
0.34	GO:0051156	glucose 6-phosphate metabolic process
0.34	GO:0019682	glyceraldehyde-3-phosphate metabolic process
0.33	GO:0072524	pyridine-containing compound metabolic process
0.33	GO:0006733	oxidoreduction coenzyme metabolic process
0.33	GO:0009057	macromolecule catabolic process

0.74	GO:0016868	intramolecular transferase activity, phosphotransferases
0.63	GO:0000287	magnesium ion binding
0.33	GO:0005515	protein binding

0.43	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.30	GO:0031224	intrinsic component of membrane

0.74

EC:5.4.2

GO:0016868

sp|Q6NYE4|ALKMO_DANRE
Alkylglycerol monooxygenase
Search

AGMO

0.93	LOW QUALITY PROTEIN: alkylglycerol monooxygenase

0.62	GO:0008610	lipid biosynthetic process
0.56	GO:0046485	ether lipid metabolic process
0.51	GO:0055114	oxidation-reduction process
0.50	GO:0006643	membrane lipid metabolic process
0.35	GO:0006641	triglyceride metabolic process
0.32	GO:0044249	cellular biosynthetic process

0.62	GO:0004497	monooxygenase activity
0.60	GO:0005506	iron ion binding
0.49	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

0.49	GO:0005783	endoplasmic reticulum
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.49

EC:1.14

GO:0016705

sp|Q6NYE7|TM192_DANRE
Transmembrane protein 192
Search

TMEM192

0.90	Transmembrane protein 192

0.42

GO:0042803

protein homodimerization activity

0.48	GO:0005765	lysosomal membrane
0.48	GO:0005770	late endosome
0.43	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005654	nucleoplasm
0.38	GO:0070062	extracellular exosome
0.36	GO:0005794	Golgi apparatus
0.36	GO:0005783	endoplasmic reticulum
0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q6NYF0|LACB2_DANRE
Endoribonuclease LACTB2
Search

LACTB2

0.94	Lactamase beta 2

0.68	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.44	GO:0017001	antibiotic catabolic process
0.37	GO:0046777	protein autophosphorylation

0.76	GO:0003727	single-stranded RNA binding
0.68	GO:0004521	endoribonuclease activity
0.62	GO:0008270	zinc ion binding
0.44	GO:0008800	beta-lactamase activity
0.37	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.36	GO:0005515	protein binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.72

GO:0005759

mitochondrial matrix

0.44

EC:3.5.2.6

GO:0008800

sp|Q6NYF1|YIPF4_DANRE
Protein YIPF4
Search

tr|Q6NYF7|Q6NYF7_DANRE
ATP synthase-coupling factor 6, mitochondrial
Search

ATP5J

0.95	Mitochondrial ATP synthase-coupling factor 6

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.35	GO:0021762	substantia nigra development
0.34	GO:0050829	defense response to Gram-negative bacterium

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.36	GO:0016887	ATPase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0046872	metal ion binding

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.30	GO:0016021	integral component of membrane

0.36

GO:0016887

tr|Q6NYG0|Q6NYG0_DANRE
Purine nucleoside phosphorylase
Search

0.46	Purine nucleoside phosphorylase

0.66	GO:0009116	nucleoside metabolic process
0.45	GO:0034418	urate biosynthetic process
0.44	GO:0070970	interleukin-2 secretion
0.43	GO:0046638	positive regulation of alpha-beta T cell differentiation
0.43	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway
0.43	GO:0042102	positive regulation of T cell proliferation
0.42	GO:0072526	pyridine-containing compound catabolic process
0.41	GO:1901658	glycosyl compound catabolic process
0.41	GO:0072523	purine-containing compound catabolic process
0.40	GO:0006955	immune response

0.78	GO:0004731	purine-nucleoside phosphorylase activity
0.45	GO:0002060	purine nucleobase binding
0.42	GO:0042301	phosphate ion binding
0.39	GO:0001882	nucleoside binding
0.36	GO:0008144	drug binding

0.39	GO:0005829	cytosol
0.33	GO:0005856	cytoskeleton

0.78

EC:2.4.2.1

GO:0004731

sp|Q6NYG4|CYYR1_DANRE
Cysteine and tyrosine-rich protein 1
Search

CYYR1

0.97	Cysteine and tyrosine-rich protein 1

0.30

GO:0044425

membrane part

sp|Q6NYG6|TDRD3_DANRE
Tudor domain-containing protein 3
Search

TDRD3

0.94	Tudor domain-containing protein 3

0.64	GO:0006397	mRNA processing
0.45	GO:2001141	regulation of RNA biosynthetic process
0.43	GO:0016569	covalent chromatin modification

0.60	GO:0035064	methylated histone binding
0.58	GO:0003713	transcription coactivator activity
0.56	GO:0003682	chromatin binding
0.55	GO:0003723	RNA binding

0.62	GO:0035145	exon-exon junction complex
0.51	GO:0005794	Golgi apparatus
0.50	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol

sp|Q6NYG8|DPYD_DANRE
Dihydropyrimidine dehydrogenase [NADP(+)]
Search

DPYD

0.89	Dihydropyrimidine dehydrogenase [NADP(+)]

0.86	GO:0019483	beta-alanine biosynthetic process
0.59	GO:0006214	thymidine catabolic process
0.57	GO:0006206	pyrimidine nucleobase metabolic process
0.52	GO:0055114	oxidation-reduction process
0.51	GO:0046113	nucleobase catabolic process
0.49	GO:0072523	purine-containing compound catabolic process
0.49	GO:0046112	nucleobase biosynthetic process
0.48	GO:0006144	purine nucleobase metabolic process
0.48	GO:0042737	drug catabolic process
0.48	GO:0072528	pyrimidine-containing compound biosynthetic process

0.85	GO:0017113	dihydropyrimidine dehydrogenase (NADP+) activity
0.66	GO:0051539	4 iron, 4 sulfur cluster binding
0.52	GO:0004152	dihydroorotate dehydrogenase activity
0.49	GO:0042803	protein homodimerization activity
0.36	GO:0050661	NADP binding
0.36	GO:0002058	uracil binding
0.35	GO:0046872	metal ion binding
0.35	GO:0050660	flavin adenine dinucleotide binding
0.35	GO:0004159	dihydrouracil dehydrogenase (NAD+) activity
0.33	GO:0010181	FMN binding

0.49	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.85	EC:1.3.1.2	GO:0017113
0.52	KEGG:R01868	GO:0004152

tr|Q6NYG9|Q6NYG9_DANRE
Interferon regulatory factor 2-binding protein-like
Search

0.77	Interferon regulatory factor 2 binding protein like

0.57	GO:0000122	negative regulation of transcription by RNA polymerase II
0.55	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0046543	development of secondary female sexual characteristics
0.39	GO:0006351	transcription, DNA-templated

0.45	GO:0046872	metal ion binding
0.38	GO:0003714	transcription corepressor activity
0.33	GO:0016874	ligase activity

0.57	GO:0005654	nucleoplasm
0.35	GO:0005615	extracellular space
0.34	GO:0005737	cytoplasm

0.33

GO:0016874

tr|Q6NYH0|Q6NYH0_DANRE
Dual specificity protein phosphatase
Search

DUSP7

0.72	Dual specificity protein phosphatase

0.84	GO:0000188	inactivation of MAPK activity
0.71	GO:0006470	protein dephosphorylation
0.43	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.41	GO:0042663	regulation of endodermal cell fate specification
0.41	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway
0.40	GO:0060420	regulation of heart growth
0.40	GO:0043065	positive regulation of apoptotic process
0.40	GO:0051409	response to nitrosative stress
0.40	GO:0009953	dorsal/ventral pattern formation
0.35	GO:0016310	phosphorylation

0.84	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.67	GO:0004725	protein tyrosine phosphatase activity
0.35	GO:0016301	kinase activity
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0005515	protein binding

0.45	GO:0005829	cytosol
0.33	GO:0005654	nucleoplasm
0.33	GO:0005840	ribosome

0.84

GO:0017017

sp|Q6NYH1|IF122_DANRE
Intraflagellar transport protein 122 homolog
Search

IFT122

0.96	Intraflagellar transport protein 122

0.51	GO:0035721	intraciliary retrograde transport
0.50	GO:0061512	protein localization to cilium
0.50	GO:0045879	negative regulation of smoothened signaling pathway
0.49	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway
0.49	GO:0035720	intraciliary anterograde transport
0.49	GO:0060971	embryonic heart tube left/right pattern formation
0.49	GO:0010172	embryonic body morphogenesis
0.49	GO:0007227	signal transduction downstream of smoothened
0.49	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.48	GO:0021513	spinal cord dorsal/ventral patterning

0.77	GO:0031514	motile cilium
0.50	GO:0030991	intraciliary transport particle A
0.47	GO:0097546	ciliary base
0.47	GO:0032391	photoreceptor connecting cilium
0.46	GO:0036064	ciliary basal body
0.42	GO:0005654	nucleoplasm
0.41	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q6NYI0|HERP2_DANRE
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein
Search

HERPUD2

0.89	Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein-like

0.46	GO:0006986	response to unfolded protein
0.44	GO:0007283	spermatogenesis

0.30

GO:0044425

membrane part

tr|Q6NYJ1|Q6NYJ1_DANRE
LIM and SH3 protein 1
Search

LASP1

0.94	LIM zinc-binding domain-containing Nebulette

0.36	GO:0006811	ion transport
0.35	GO:0072359	circulatory system development
0.35	GO:0048646	anatomical structure formation involved in morphogenesis
0.34	GO:0055085	transmembrane transport
0.34	GO:0055002	striated muscle cell development
0.34	GO:0031032	actomyosin structure organization
0.34	GO:0014706	striated muscle tissue development
0.34	GO:0009967	positive regulation of signal transduction
0.33	GO:0007015	actin filament organization
0.33	GO:0032989	cellular component morphogenesis

0.52	GO:0046872	metal ion binding
0.51	GO:0045296	cadherin binding
0.50	GO:0051015	actin filament binding
0.35	GO:0015075	ion transmembrane transporter activity
0.34	GO:0031005	filamin binding
0.34	GO:0005070	SH3/SH2 adaptor activity
0.34	GO:0005523	tropomyosin binding
0.33	GO:0003700	DNA binding transcription factor activity

0.51	GO:0005925	focal adhesion
0.40	GO:0005938	cell cortex
0.39	GO:0005856	cytoskeleton
0.37	GO:0070062	extracellular exosome
0.35	GO:0044446	intracellular organelle part
0.34	GO:0030018	Z disc
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|Q6NYJ2|Q6NYJ2_DANRE
Suppressor of cytokine signaling 3b
Search

SOCS3

0.97	Suppressor of cytokine signaling 3

0.84	GO:0007259	JAK-STAT cascade
0.76	GO:0043066	negative regulation of apoptotic process
0.66	GO:0016567	protein ubiquitination
0.58	GO:0046426	negative regulation of JAK-STAT cascade
0.54	GO:0046627	negative regulation of insulin receptor signaling pathway
0.50	GO:0071345	cellular response to cytokine stimulus
0.50	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation
0.50	GO:0042509	regulation of tyrosine phosphorylation of STAT protein
0.50	GO:0032102	negative regulation of response to external stimulus
0.50	GO:0060708	spongiotrophoblast differentiation

0.50	GO:0001784	phosphotyrosine residue binding
0.46	GO:0004860	protein kinase inhibitor activity
0.46	GO:0008269	JAK pathway signal transduction adaptor activity
0.45	GO:0005159	insulin-like growth factor receptor binding
0.32	GO:0003924	GTPase activity
0.32	GO:0005525	GTP binding

0.45

GO:0005622

intracellular

sp|Q6NYJ3|TE2IP_DANRE
Telomeric repeat-binding factor 2-interacting protein 1
Search

0.10	Telomeric repeat-binding factor 2-interacting protein 1

0.57	GO:0070198	protein localization to chromosome, telomeric region
0.57	GO:0031848	protection from non-homologous end joining at telomere
0.55	GO:0032205	negative regulation of telomere maintenance
0.55	GO:1901224	positive regulation of NIK/NF-kappaB signaling
0.55	GO:1901985	positive regulation of protein acetylation
0.55	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.54	GO:0048239	negative regulation of DNA recombination at telomere
0.51	GO:0010569	regulation of double-strand break repair via homologous recombination
0.51	GO:0010833	telomere maintenance via telomere lengthening
0.50	GO:0001933	negative regulation of protein phosphorylation

0.57	GO:0098505	G-rich strand telomeric DNA binding
0.54	GO:0019902	phosphatase binding
0.35	GO:0003743	translation initiation factor activity

0.57	GO:0070187	shelterin complex
0.54	GO:0030870	Mre11 complex
0.51	GO:0016604	nuclear body
0.47	GO:0005829	cytosol
0.45	GO:0005635	nuclear envelope

tr|Q6NYJ5|Q6NYJ5_DANRE
Synaptotagmin binding, cytoplasmic RNA interacting protein, like
Search

SYNCRIP

0.83	Synaptotagmin binding, cytoplasmic RNA interacting protein, like

0.67	GO:0070934	CRD-mediated mRNA stabilization
0.63	GO:0071346	cellular response to interferon-gamma
0.57	GO:0017148	negative regulation of translation

0.59	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.67	GO:0097452	GAIT complex
0.66	GO:0070937	CRD-mediated mRNA stability complex
0.62	GO:0071204	histone pre-mRNA 3'end processing complex
0.60	GO:0071013	catalytic step 2 spliceosome

tr|Q6NYJ8|Q6NYJ8_DANRE
MOB kinase activator 1A
Search

MOB1A

0.78	Deoxycytidine kinase

0.60	GO:0035329	hippo signaling
0.55	GO:0031952	regulation of protein autophosphorylation
0.51	GO:0016310	phosphorylation
0.51	GO:0042327	positive regulation of phosphorylation
0.43	GO:0001756	somitogenesis
0.42	GO:0008283	cell proliferation
0.42	GO:0007417	central nervous system development
0.34	GO:0098656	anion transmembrane transport
0.34	GO:0015698	inorganic anion transport

0.53	GO:0019209	kinase activator activity
0.53	GO:0016301	kinase activity
0.51	GO:0019900	kinase binding
0.35	GO:0046872	metal ion binding
0.35	GO:0005452	inorganic anion exchanger activity

0.53	GO:0005730	nucleolus
0.51	GO:0005829	cytosol
0.39	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

tr|Q6NYK0|Q6NYK0_DANRE
Tescalcin a
Search

0.97	Calcineurin B ous protein 3

0.48	GO:0032417	positive regulation of sodium:proton antiporter activity
0.48	GO:0030854	positive regulation of granulocyte differentiation
0.47	GO:0071300	cellular response to retinoic acid
0.45	GO:0072659	protein localization to plasma membrane
0.44	GO:0050821	protein stabilization
0.44	GO:0045654	positive regulation of megakaryocyte differentiation
0.43	GO:0033628	regulation of cell adhesion mediated by integrin
0.42	GO:0051604	protein maturation
0.41	GO:0008285	negative regulation of cell proliferation
0.40	GO:0045893	positive regulation of transcription, DNA-templated

0.70	GO:0005509	calcium ion binding
0.40	GO:0004860	protein kinase inhibitor activity
0.40	GO:0019212	phosphatase inhibitor activity
0.38	GO:0042803	protein homodimerization activity
0.36	GO:0000287	magnesium ion binding
0.33	GO:0003677	DNA binding

0.45	GO:0030027	lamellipodium
0.40	GO:0032587	ruffle membrane
0.39	GO:0005634	nucleus
0.39	GO:0005829	cytosol

tr|Q6NYK1|Q6NYK1_DANRE
Deoxyhypusine synthase
Search

DHPS

0.63	Deoxyhypusine synthase

0.78	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine
0.54	GO:0042102	positive regulation of T cell proliferation
0.52	GO:0042593	glucose homeostasis
0.51	GO:0008216	spermidine metabolic process
0.45	GO:0031017	exocrine pancreas development
0.45	GO:0003323	type B pancreatic cell development
0.39	GO:0006598	polyamine catabolic process
0.39	GO:0051289	protein homotetramerization
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0009059	macromolecule biosynthetic process

0.61	GO:0034038	deoxyhypusine synthase activity
0.49	GO:0042802	identical protein binding
0.32	GO:0016787	hydrolase activity

0.36

GO:0005737

cytoplasm

0.61

EC:2.5.1.46

GO:0034038

tr|Q6NYK2|Q6NYK2_DANRE
Retinal outer segment membrane protein 1a
Search

PRPH2

0.96	Retinal outer segment membrane protein 1

0.78	GO:0007601	visual perception
0.52	GO:0060041	retina development in camera-type eye
0.44	GO:0007166	cell surface receptor signaling pathway
0.39	GO:0007155	cell adhesion
0.35	GO:1903525	regulation of membrane tubulation
0.35	GO:0009645	response to low light intensity stimulus
0.34	GO:0051289	protein homotetramerization
0.34	GO:0051258	protein polymerization

0.34

GO:0005515

protein binding

0.53	GO:0001750	photoreceptor outer segment
0.42	GO:0005887	integral component of plasma membrane
0.34	GO:0055037	recycling endosome
0.34	GO:0005795	Golgi stack
0.33	GO:0005783	endoplasmic reticulum
0.32	GO:0043234	protein complex

sp|Q6NYK3|SPRE2_DANRE
Sprouty-related, EVH1 domain-containing protein 2
Search

SPRED2

0.96	Sprouty-related, EVH1 domain-containing protein 2 isoform a

0.68	GO:0007275	multicellular organism development
0.68	GO:0009966	regulation of signal transduction
0.51	GO:0090311	regulation of protein deacetylation
0.51	GO:2001022	positive regulation of response to DNA damage stimulus
0.50	GO:0010801	negative regulation of peptidyl-threonine phosphorylation
0.49	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.47	GO:0023056	positive regulation of signaling
0.47	GO:0010647	positive regulation of cell communication
0.46	GO:0023057	negative regulation of signaling
0.46	GO:0010648	negative regulation of cell communication

0.53	GO:0005173	stem cell factor receptor binding
0.50	GO:0030291	protein serine/threonine kinase inhibitor activity
0.49	GO:0019901	protein kinase binding

0.47	GO:0031410	cytoplasmic vesicle
0.40	GO:0005886	plasma membrane
0.40	GO:0012506	vesicle membrane
0.39	GO:0098805	whole membrane
0.39	GO:0098588	bounding membrane of organelle
0.38	GO:0012505	endomembrane system
0.36	GO:0044446	intracellular organelle part
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q6NYK8|MARH5_DANRE
E3 ubiquitin-protein ligase MARCH5
Search

MARCH5

0.85	Membrane associated ring-CH-type finger 5

0.64	GO:0090141	positive regulation of mitochondrial fission
0.63	GO:0090344	negative regulation of cell aging
0.61	GO:0051865	protein autoubiquitination
0.59	GO:0000209	protein polyubiquitination
0.58	GO:0070585	protein localization to mitochondrion

0.63	GO:0008270	zinc ion binding
0.55	GO:0051020	GTPase binding
0.55	GO:0004842	ubiquitin-protein transferase activity

0.57	GO:0005741	mitochondrial outer membrane
0.54	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.55

GO:0004842

tr|Q6NYL2|Q6NYL2_DANRE
Eukaryotic translation initiation factor 4E binding protein 2
Search

EIF4EBP2

0.93	Eukaryotic translation initiation factor 4E-binding protein 2

0.82	GO:0045947	negative regulation of translational initiation
0.61	GO:0006413	translational initiation
0.51	GO:0031929	TOR signaling
0.50	GO:0008286	insulin receptor signaling pathway
0.49	GO:0035176	social behavior
0.48	GO:0007613	memory
0.48	GO:0019933	cAMP-mediated signaling
0.48	GO:0048167	regulation of synaptic plasticity
0.43	GO:0000082	G1/S transition of mitotic cell cycle
0.42	GO:0045931	positive regulation of mitotic cell cycle

0.86	GO:0008190	eukaryotic initiation factor 4E binding
0.61	GO:0003743	translation initiation factor activity
0.53	GO:0030371	translation repressor activity
0.35	GO:0051721	protein phosphatase 2A binding

0.41	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.33	GO:0043234	protein complex

sp|Q6NYL3|ECHP_DANRE
Peroxisomal bifunctional enzyme
Search

EHHADH

0.75	Peroxisomal bifunctional enzyme

0.69	GO:0006631	fatty acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.44	GO:0044242	cellular lipid catabolic process
0.43	GO:0030258	lipid modification
0.43	GO:0072329	monocarboxylic acid catabolic process
0.43	GO:0006475	internal protein amino acid acetylation

0.76	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
0.55	GO:0070403	NAD+ binding
0.44	GO:0004165	dodecenoyl-CoA delta-isomerase activity
0.43	GO:0004300	enoyl-CoA hydratase activity
0.39	GO:0005102	receptor binding
0.38	GO:0019899	enzyme binding
0.38	GO:0016508	long-chain-enoyl-CoA hydratase activity

0.44	GO:0005777	peroxisome
0.37	GO:0031907	microbody lumen
0.36	GO:0005739	mitochondrion
0.35	GO:0005829	cytosol

0.76

EC:1.1.1.35

GO:0003857

sp|Q6NYL5|ALAT2_DANRE
Alanine aminotransferase 2-like
Search

0.72	Mitochondrial alanine aminotransferase

0.50	GO:0006103	2-oxoglutarate metabolic process
0.49	GO:0042851	L-alanine metabolic process
0.49	GO:0009058	biosynthetic process
0.39	GO:0009080	pyruvate family amino acid catabolic process

0.67	GO:0030170	pyridoxal phosphate binding
0.63	GO:0008483	transaminase activity

0.41	GO:0005739	mitochondrion
0.36	GO:0005615	extracellular space
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part

0.63

EC:2.6.1

GO:0008483

tr|Q6NYL7|Q6NYL7_DANRE
Zgc:77517
Search

KRT18

0.92	'Keratin, type I cytoskeletal 18'

0.43	GO:0043000	Golgi to plasma membrane CFTR protein transport
0.42	GO:0045104	intermediate filament cytoskeleton organization
0.40	GO:0097284	hepatocyte apoptotic process
0.39	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.39	GO:0097191	extrinsic apoptotic signaling pathway
0.39	GO:0043066	negative regulation of apoptotic process
0.39	GO:0098609	cell-cell adhesion
0.35	GO:0050708	regulation of protein secretion
0.35	GO:0031424	keratinization
0.35	GO:0009267	cellular response to starvation

0.62	GO:0005198	structural molecule activity
0.41	GO:0098641	cadherin binding involved in cell-cell adhesion
0.41	GO:0097110	scaffold protein binding
0.33	GO:0003723	RNA binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0003677	DNA binding

0.79	GO:0005882	intermediate filament
0.41	GO:0034451	centriolar satellite
0.40	GO:0005913	cell-cell adherens junction
0.39	GO:0005829	cytosol
0.34	GO:0071944	cell periphery
0.34	GO:0070062	extracellular exosome
0.33	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005730	nucleolus
0.30	GO:0016020	membrane

sp|Q6NYM1|KLH21_DANRE
Kelch-like protein 21
Search

KLHL21

0.97	Kelch like family member 21

0.85	GO:0035853	chromosome passenger complex localization to spindle midzone
0.74	GO:0032465	regulation of cytokinesis
0.73	GO:0016567	protein ubiquitination
0.46	GO:0051301	cell division
0.46	GO:0007049	cell cycle
0.42	GO:0006511	ubiquitin-dependent protein catabolic process
0.39	GO:0043687	post-translational protein modification
0.33	GO:0006281	DNA repair
0.33	GO:0032259	methylation
0.32	GO:0016310	phosphorylation

0.74	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0003908	methylated-DNA-[protein]-cysteine S-methyltransferase activity
0.33	GO:0016301	kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.85	GO:0005827	polar microtubule
0.83	GO:0031463	Cul3-RING ubiquitin ligase complex
0.38	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.34	EC:2.1.1.63	GO:0003908
0.74	KEGG:R03876	GO:0004842

tr|Q6NYN3|Q6NYN3_DANRE
Importin 7
Search

IPO7

0.90

Importin

0.69	GO:0006886	intracellular protein transport
0.54	GO:0006606	protein import into nucleus
0.50	GO:0045087	innate immune response
0.40	GO:0007165	signal transduction
0.35	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity
0.34	GO:0060964	regulation of gene silencing by miRNA
0.33	GO:0016032	viral process

0.79	GO:0008536	Ran GTPase binding
0.53	GO:0046332	SMAD binding
0.51	GO:0042393	histone binding
0.43	GO:0008565	protein transporter activity
0.34	GO:0030695	GTPase regulator activity
0.32	GO:0003676	nucleic acid binding

0.57	GO:0005634	nucleus
0.48	GO:0005829	cytosol
0.46	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.42	GO:0012505	endomembrane system
0.40	GO:0031975	envelope
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q6NYN7|S22A6_DANRE
Solute carrier family 22 member 6
Search

0.80	Solute carrier family 22 (organic anion transporter), member 6, like

0.54	GO:0097254	renal tubular secretion
0.54	GO:0015742	alpha-ketoglutarate transport
0.53	GO:0055085	transmembrane transport
0.49	GO:0043252	sodium-independent organic anion transport
0.47	GO:0015698	inorganic anion transport
0.45	GO:0015747	urate transport
0.38	GO:0031427	response to methotrexate
0.36	GO:0051260	protein homooligomerization
0.33	GO:0008643	carbohydrate transport

0.54	GO:0022857	transmembrane transporter activity
0.37	GO:0031404	chloride ion binding
0.36	GO:0042803	protein homodimerization activity

0.50	GO:0016323	basolateral plasma membrane
0.46	GO:0005887	integral component of plasma membrane
0.37	GO:0005901	caveola
0.37	GO:0070062	extracellular exosome
0.34	GO:0043234	protein complex

sp|Q6NYP0|TM208_DANRE
Transmembrane protein 208
Search

TMEM208

0.47	LOW QUALITY PROTEIN: transmembrane protein 208

0.51	GO:0006624	vacuolar protein processing
0.40	GO:0006914	autophagy

0.46	GO:0005773	vacuole
0.39	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q6NYP8|N6MT2_DANRE
Protein-lysine N-methyltransferase n6amt2
Search

EEF1AKMT1

0.97	N-6 adenine-specific DNA methyltransferase 2

0.70

GO:0018022

peptidyl-lysine methylation

0.70	GO:0016279	protein-lysine N-methyltransferase activity
0.50	GO:0003676	nucleic acid binding
0.32	GO:0046872	metal ion binding

0.46	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome

0.70

GO:0016279

tr|Q6NYQ2|Q6NYQ2_DANRE
Germ cell-less homolog 1 (Drosophila)
Search

GMCL1

0.97	Germ cell-less, spermatogenesis associated 1

0.50	GO:1903506	regulation of nucleic acid-templated transcription
0.50	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.50	GO:0010468	regulation of gene expression
0.42	GO:0007283	spermatogenesis
0.40	GO:0030154	cell differentiation
0.40	GO:0007275	multicellular organism development
0.37	GO:0016567	protein ubiquitination
0.35	GO:0008380	RNA splicing

0.68

GO:0042802

identical protein binding

0.72	GO:0016363	nuclear matrix
0.65	GO:0005635	nuclear envelope
0.58	GO:0000151	ubiquitin ligase complex
0.30	GO:0031224	intrinsic component of membrane

tr|Q6NYQ7|Q6NYQ7_DANRE
Nicotinamide nucleotide transhydrogenase
Search

NNT

0.70	Nicotinamide nucleotide transhydrogenase

0.61	GO:0015992	proton transport
0.52	GO:0055114	oxidation-reduction process
0.48	GO:0072593	reactive oxygen species metabolic process
0.44	GO:0006739	NADP metabolic process
0.33	GO:0006101	citrate metabolic process
0.33	GO:0098662	inorganic cation transmembrane transport
0.33	GO:0006091	generation of precursor metabolites and energy

0.78	GO:0008746	NAD(P)+ transhydrogenase activity
0.48	GO:0050661	NADP binding
0.42	GO:0051287	NAD binding
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.44	GO:0005739	mitochondrion
0.40	GO:0019866	organelle inner membrane
0.33	GO:0070469	respiratory chain
0.30	GO:0016021	integral component of membrane

0.78	EC:1.6.1	GO:0008746
0.78	KEGG:R00112	GO:0008746

tr|Q6NYQ9|Q6NYQ9_DANRE
Polr3f protein
Search

POLR3F

0.76	DNA-directed RNA polymerase III subunit RPC6

0.78	GO:0006383	transcription by RNA polymerase III
0.58	GO:0032728	positive regulation of interferon-beta production
0.55	GO:0045089	positive regulation of innate immune response
0.44	GO:0060041	retina development in camera-type eye
0.37	GO:0045087	innate immune response
0.37	GO:0051607	defense response to virus
0.35	GO:0006359	regulation of transcription by RNA polymerase III

0.68	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.51	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.79	GO:0005666	DNA-directed RNA polymerase III complex
0.33	GO:0005829	cytosol

0.68

EC:2.7.7.6

GO:0003899

tr|Q6NYR0|Q6NYR0_DANRE
Serine hydroxymethyltransferase
Search

SHMT1

0.48	Serine hydroxymethyltransferase, cytosolic

0.76	GO:0019264	glycine biosynthetic process from serine
0.75	GO:0051289	protein homotetramerization
0.73	GO:0035999	tetrahydrofolate interconversion
0.68	GO:1904481	response to tetrahydrofolate
0.67	GO:0006565	L-serine catabolic process
0.62	GO:1990830	cellular response to leukemia inhibitory factor
0.60	GO:0071229	cellular response to acid chemical
0.59	GO:0071417	cellular response to organonitrogen compound
0.58	GO:0006231	dTMP biosynthetic process
0.58	GO:0046655	folic acid metabolic process

0.77	GO:0004372	glycine hydroxymethyltransferase activity
0.67	GO:0070905	serine binding
0.66	GO:0030170	pyridoxal phosphate binding
0.65	GO:0000900	translation repressor activity, nucleic acid binding
0.60	GO:0048027	mRNA 5'-UTR binding
0.56	GO:0042803	protein homodimerization activity
0.51	GO:0008732	L-allo-threonine aldolase activity
0.50	GO:0008168	methyltransferase activity

0.61	GO:0005829	cytosol
0.48	GO:0005634	nucleus
0.48	GO:0005739	mitochondrion
0.47	GO:0070062	extracellular exosome

0.77

EC:2.1.2.1

GO:0004372

sp|Q6NYR8|NPL_DANRE
N-acetylneuraminate lyase
Search

NPL

0.64	N-acetylneuraminate pyruvate lyase

0.43	GO:0019262	N-acetylneuraminate catabolic process
0.43	GO:0005975	carbohydrate metabolic process
0.36	GO:0000002	mitochondrial genome maintenance
0.36	GO:0000723	telomere maintenance
0.35	GO:0032392	DNA geometric change
0.34	GO:0006310	DNA recombination
0.34	GO:0006281	DNA repair

0.62	GO:0016829	lyase activity
0.49	GO:0042802	identical protein binding
0.36	GO:0043141	ATP-dependent 5'-3' DNA helicase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003676	nucleic acid binding

0.42	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus

0.62

EC:4

GO:0016829

tr|Q6NYS3|Q6NYS3_DANRE
Cullin 1a
Search

CUL1

0.81

cullin-1

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.52	GO:0006513	protein monoubiquitination
0.50	GO:0008283	cell proliferation
0.49	GO:0006915	apoptotic process
0.49	GO:0009887	animal organ morphogenesis
0.49	GO:0010498	proteasomal protein catabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0010265	SCF complex assembly
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway

0.79	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0061630	ubiquitin protein ligase activity

0.74	GO:0031461	cullin-RING ubiquitin ligase complex
0.55	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex
0.35	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|Q6NYS4|Q6NYS4_DANRE
Phosphatidylethanolamine binding protein
Search

PEBP1

0.63	Phosphatidylethanolamine-binding protein 1

0.54	GO:0010951	negative regulation of endopeptidase activity
0.51	GO:0060409	positive regulation of acetylcholine metabolic process
0.51	GO:0048240	sperm capacitation
0.49	GO:0051412	response to corticosterone
0.49	GO:0010243	response to organonitrogen compound
0.48	GO:0043950	positive regulation of cAMP-mediated signaling
0.48	GO:0051602	response to electrical stimulus
0.48	GO:0042755	eating behavior
0.48	GO:0002026	regulation of the force of heart contraction
0.48	GO:0014823	response to activity

0.69	GO:0019901	protein kinase binding
0.55	GO:0004867	serine-type endopeptidase inhibitor activity
0.52	GO:0008289	lipid binding
0.44	GO:0032559	adenyl ribonucleotide binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0005102	receptor binding
0.39	GO:0019210	kinase inhibitor activity
0.37	GO:0003723	RNA binding

0.49	GO:0043209	myelin sheath
0.47	GO:0043679	axon terminus
0.46	GO:0009986	cell surface
0.46	GO:0005791	rough endoplasmic reticulum
0.46	GO:0008021	synaptic vesicle
0.46	GO:0043025	neuronal cell body
0.45	GO:0045177	apical part of cell
0.45	GO:0005615	extracellular space
0.44	GO:0005741	mitochondrial outer membrane
0.43	GO:1903561	extracellular vesicle

sp|Q6NYS8|OST48_DANRE
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Search

DDOST

0.78	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

0.85	GO:0018279	protein N-linked glycosylation via asparagine
0.52	GO:0042110	T cell activation
0.50	GO:0034097	response to cytokine
0.38	GO:0006334	nucleosome assembly
0.37	GO:0007018	microtubule-based movement
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0070828	heterochromatin organization
0.34	GO:0034389	lipid particle organization
0.34	GO:0007030	Golgi organization
0.32	GO:0006355	regulation of transcription, DNA-templated

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.37	GO:0003777	microtubule motor activity
0.37	GO:0008017	microtubule binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0003677	DNA binding
0.34	GO:0003682	chromatin binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.42	GO:0043234	protein complex
0.41	GO:1990234	transferase complex
0.37	GO:0000786	nucleosome
0.35	GO:0035577	azurophil granule membrane
0.35	GO:0005634	nucleus
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016757

sp|Q6NYT1|MED8_DANRE
Mediator of RNA polymerase II transcription subunit 8
Search

MED8

0.96	Mediator of RNA polymerase II transcription subunit 8

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.38	GO:0016567	protein ubiquitination

0.78	GO:0001104	RNA polymerase II transcription cofactor activity
0.34	GO:0005515	protein binding

0.77	GO:0016592	mediator complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q6NYT3|IER5L_DANRE
Immediate early response gene 5-like protein
Search

IER5L

0.94	Immediate early response 5 like

0.80	GO:1900036	positive regulation of cellular response to heat
0.69	GO:0034605	cellular response to heat
0.66	GO:0042127	regulation of cell proliferation
0.65	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0006351	transcription, DNA-templated

0.64

GO:0042802

identical protein binding

0.69	GO:0000159	protein phosphatase type 2A complex
0.54	GO:0005634	nucleus
0.45	GO:0005737	cytoplasm

tr|Q6NYT8|Q6NYT8_DANRE
Lysyl oxidase
Search

LOX

0.87	Lysyl oxidase a

0.53	GO:0048251	elastic fiber assembly
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0035904	aorta development
0.52	GO:0030199	collagen fibril organization
0.52	GO:0048513	animal organ development
0.51	GO:0048514	blood vessel morphogenesis
0.50	GO:0060541	respiratory system development
0.49	GO:0035295	tube development
0.46	GO:0061448	connective tissue development
0.45	GO:0001501	skeletal system development

0.77	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
0.72	GO:0005507	copper ion binding
0.42	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0035091	phosphatidylinositol binding
0.34	GO:0005515	protein binding

0.49	GO:0005581	collagen trimer
0.48	GO:0005578	proteinaceous extracellular matrix
0.48	GO:0005615	extracellular space
0.36	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.77

EC:1.4.3

GO:0016641

sp|Q6NYU2|HELZ_DANRE
Probable helicase with zinc finger domain
Search

HELZ

0.85	Helicase with zinc finger

0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:2001141	regulation of RNA biosynthetic process
0.35	GO:0010468	regulation of gene expression

0.57	GO:0004386	helicase activity
0.52	GO:0046872	metal ion binding
0.36	GO:0003700	DNA binding transcription factor activity
0.36	GO:0003676	nucleic acid binding
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q6NYU3|NDF6A_DANRE
Neurogenic differentiation factor 6-A
Search

NEUROD6

0.92	Neurogenic differentiation factor

0.74	GO:0007399	nervous system development
0.67	GO:0030154	cell differentiation
0.57	GO:0006355	regulation of transcription, DNA-templated
0.56	GO:0060322	head development
0.55	GO:0006366	transcription by RNA polymerase II
0.54	GO:0048513	animal organ development
0.53	GO:1903508	positive regulation of nucleic acid-templated transcription
0.53	GO:0010628	positive regulation of gene expression
0.52	GO:0060730	regulation of intestinal epithelial structure maintenance
0.51	GO:2000675	negative regulation of type B pancreatic cell apoptotic process

0.68	GO:0046983	protein dimerization activity
0.58	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0001105	RNA polymerase II transcription coactivator activity
0.50	GO:0001102	RNA polymerase II activating transcription factor binding
0.46	GO:0003682	chromatin binding
0.33	GO:0005509	calcium ion binding

0.57	GO:0005634	nucleus
0.46	GO:0005667	transcription factor complex
0.40	GO:0044446	intracellular organelle part
0.37	GO:0005737	cytoplasm
0.34	GO:0070013	intracellular organelle lumen

tr|Q6NYU5|Q6NYU5_DANRE
Gap junction protein
Search

0.58	Gap junction protein (Fragment)

0.60	GO:0007154	cell communication
0.46	GO:0050908	detection of light stimulus involved in visual perception
0.45	GO:0007416	synapse assembly
0.43	GO:0007276	gamete generation
0.39	GO:0055085	transmembrane transport

0.50	GO:0005243	gap junction channel activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.83	GO:0005922	connexin complex
0.30	GO:0016021	integral component of membrane

sp|Q6NYU6|MIDN_DANRE
Midnolin
Search

MIDN

0.88

Midnolin

0.54	GO:0033132	negative regulation of glucokinase activity
0.52	GO:0046676	negative regulation of insulin secretion

0.48	GO:0019900	kinase binding
0.35	GO:0003723	RNA binding

0.71	GO:0005730	nucleolus
0.67	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q6NYU7|UPP_DANRE
Uracil phosphoribosyltransferase homolog
Search

UPRT

0.44	Adenine phosphoribosyltransferase

0.66	GO:0009116	nucleoside metabolic process
0.46	GO:0008655	pyrimidine-containing compound salvage
0.44	GO:0006206	pyrimidine nucleobase metabolic process
0.44	GO:0009174	pyrimidine ribonucleoside monophosphate biosynthetic process
0.44	GO:0009218	pyrimidine ribonucleotide metabolic process
0.43	GO:0006221	pyrimidine nucleotide biosynthetic process
0.43	GO:1901659	glycosyl compound biosynthetic process
0.42	GO:0009260	ribonucleotide biosynthetic process
0.37	GO:0007595	lactation
0.37	GO:0007565	female pregnancy

0.54	GO:0016757	transferase activity, transferring glycosyl groups
0.47	GO:0004849	uridine kinase activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.54

GO:0016757

tr|Q6NYU8|Q6NYU8_DANRE
Heterogeneous nuclear ribonucleoprotein A/B
Search

HNRNPAB

0.96	Heterogeneous nuclear ribonucleoprotein A/Bb

0.38	GO:0001837	epithelial to mesenchymal transition
0.36	GO:1904580	regulation of intracellular mRNA localization
0.36	GO:0045893	positive regulation of transcription, DNA-templated
0.36	GO:0000122	negative regulation of transcription by RNA polymerase II
0.36	GO:0071230	cellular response to amino acid stimulus
0.32	GO:0006351	transcription, DNA-templated

0.59	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.35	GO:0043565	sequence-specific DNA binding
0.35	GO:0003700	DNA binding transcription factor activity
0.35	GO:0003690	double-stranded DNA binding
0.35	GO:0044877	macromolecular complex binding

0.62	GO:0019013	viral nucleocapsid
0.56	GO:0030529	intracellular ribonucleoprotein complex
0.45	GO:0005654	nucleoplasm
0.37	GO:0090575	RNA polymerase II transcription factor complex
0.36	GO:0120111	neuron projection cytoplasm
0.35	GO:0030425	dendrite
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

tr|Q6NYV1|Q6NYV1_DANRE
Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 3
Search

PSMD3

0.90	26S proteasome non-ATPase regulatory subunit 3

0.75	GO:0042176	regulation of protein catabolic process
0.67	GO:0050790	regulation of catalytic activity
0.48	GO:0008345	larval locomotory behavior
0.47	GO:0071599	otic vesicle development
0.45	GO:0007420	brain development
0.45	GO:0006511	ubiquitin-dependent protein catabolic process
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation

0.68	GO:0030234	enzyme regulator activity
0.35	GO:0005515	protein binding
0.33	GO:0030545	receptor regulator activity

0.71	GO:1905369	endopeptidase complex
0.58	GO:0043234	protein complex
0.44	GO:0005622	intracellular
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.35	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

tr|Q6NYV3|Q6NYV3_DANRE
H1 histone family, member 0
Search

H1F0

0.97	H1 histone family, member 0 like 1

0.78	GO:0006334	nucleosome assembly
0.38	GO:0030261	chromosome condensation
0.35	GO:0000122	negative regulation of transcription by RNA polymerase II
0.35	GO:0098532	histone H3-K27 trimethylation
0.35	GO:0006567	threonine catabolic process
0.35	GO:0080182	histone H3-K4 trimethylation
0.35	GO:0016584	nucleosome positioning
0.34	GO:0006309	apoptotic DNA fragmentation
0.34	GO:0071169	establishment of protein localization to chromatin
0.34	GO:0051574	positive regulation of histone H3-K9 methylation

0.55	GO:0003677	DNA binding
0.47	GO:0003682	chromatin binding
0.35	GO:0008890	glycine C-acetyltransferase activity
0.34	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.34	GO:0032564	dATP binding
0.34	GO:0070279	vitamin B6 binding
0.33	GO:0016874	ligase activity
0.33	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity
0.33	GO:0050662	coenzyme binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.49	GO:0000791	euchromatin
0.45	GO:0015629	actin cytoskeleton
0.44	GO:0005794	Golgi apparatus
0.43	GO:0070013	intracellular organelle lumen
0.36	GO:0000792	heterochromatin
0.33	GO:0035327	transcriptionally active chromatin
0.33	GO:0070062	extracellular exosome
0.32	GO:0000776	kinetochore

0.35	EC:2.3.1.29	GO:0008890
0.35	KEGG:R00371	GO:0008890

sp|Q6NYV5|SP30L_DANRE
Histone deacetylase complex subunit SAP30L
Search

0.92	histone deacetylase complex subunit SAP30

0.62	GO:0009888	tissue development
0.61	GO:0048513	animal organ development
0.61	GO:0000122	negative regulation of transcription by RNA polymerase II
0.61	GO:0016575	histone deacetylation
0.58	GO:0061061	muscle structure development
0.54	GO:0007368	determination of left/right symmetry
0.53	GO:0030154	cell differentiation
0.52	GO:0035239	tube morphogenesis
0.52	GO:0048598	embryonic morphogenesis
0.52	GO:0072359	circulatory system development

0.73	GO:0044378	non-sequence-specific DNA binding, bending
0.70	GO:0010314	phosphatidylinositol-5-phosphate binding
0.66	GO:0031491	nucleosome binding
0.64	GO:0003712	transcription cofactor activity
0.64	GO:0042393	histone binding
0.61	GO:0004407	histone deacetylase activity
0.53	GO:0008270	zinc ion binding
0.48	GO:0070273	phosphatidylinositol-4-phosphate binding
0.48	GO:0032266	phosphatidylinositol-3-phosphate binding
0.33	GO:0016740	transferase activity

0.70	GO:0000118	histone deacetylase complex
0.60	GO:0005730	nucleolus
0.35	GO:0000790	nuclear chromatin

0.61

GO:0004407

sp|Q6NYV8|LCLT1_DANRE
Lysocardiolipin acyltransferase 1
Search

LCLAT1

0.95	LOW QUALITY PROTEIN: lysocardiolipin acyltransferase 1

0.47	GO:0060217	hemangioblast cell differentiation
0.46	GO:0001885	endothelial cell development
0.39	GO:0016024	CDP-diacylglycerol biosynthetic process
0.35	GO:0035965	cardiolipin acyl-chain remodeling
0.34	GO:0006654	phosphatidic acid biosynthetic process

0.61	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0005515	protein binding

0.48	GO:0005783	endoplasmic reticulum
0.47	GO:0005829	cytosol
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.61

EC:2.3

GO:0016746

sp|Q6NYV9|LEO1_DANRE
RNA polymerase-associated protein LEO1
Search

LEO1

0.87	RNA polymerase-associated protein LEO1

0.80	GO:0006368	transcription elongation from RNA polymerase II promoter
0.74	GO:0016570	histone modification
0.60	GO:0031442	positive regulation of mRNA 3'-end processing
0.58	GO:0048598	embryonic morphogenesis
0.57	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.57	GO:0045638	negative regulation of myeloid cell differentiation
0.56	GO:0009888	tissue development
0.56	GO:0019827	stem cell population maintenance
0.55	GO:0006513	protein monoubiquitination
0.54	GO:0006378	mRNA polyadenylation

0.52	GO:1990269	RNA polymerase II C-terminal domain phosphoserine binding
0.34	GO:0005523	tropomyosin binding

0.81	GO:0016593	Cdc73/Paf1 complex
0.55	GO:0001650	fibrillar center
0.52	GO:0005813	centrosome
0.34	GO:0036338	viral membrane
0.30	GO:0016021	integral component of membrane

tr|Q6NYW2|Q6NYW2_DANRE
Protein phosphatase 1D magnesium-dependent, delta isoform
Search

0.93	Pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial

0.72	GO:0006470	protein dephosphorylation
0.55	GO:0000086	G2/M transition of mitotic cell cycle
0.52	GO:0006342	chromatin silencing
0.51	GO:0009617	response to bacterium
0.49	GO:0006306	DNA methylation
0.38	GO:0009267	cellular response to starvation
0.34	GO:0006367	transcription initiation from RNA polymerase II promoter
0.34	GO:0008285	negative regulation of cell proliferation
0.34	GO:0006468	protein phosphorylation
0.34	GO:0009314	response to radiation

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.56	GO:0051019	mitogen-activated protein kinase binding
0.50	GO:0046872	metal ion binding
0.35	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0003677	DNA binding

0.47	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

0.35

GO:0004674

sp|Q6NYW6|CLAP2_DANRE
CLIP-associating protein 2
Search

CLASP2

0.86	CLIP-associating protein 2

0.71	GO:0010458	exit from mitosis
0.69	GO:0034453	microtubule anchoring
0.68	GO:0031110	regulation of microtubule polymerization or depolymerization
0.67	GO:0007052	mitotic spindle organization
0.67	GO:0007030	Golgi organization
0.67	GO:0031023	microtubule organizing center organization
0.66	GO:0007020	microtubule nucleation
0.63	GO:1903690	negative regulation of wound healing, spreading of epidermal cells
0.63	GO:1904259	regulation of basement membrane assembly involved in embryonic body morphogenesis
0.62	GO:0090091	positive regulation of extracellular matrix disassembly

0.69	GO:0051010	microtubule plus-end binding
0.60	GO:0002162	dystroglycan binding
0.59	GO:1990782	protein tyrosine kinase binding
0.55	GO:0051015	actin filament binding

0.72	GO:0005794	Golgi apparatus
0.69	GO:0032587	ruffle membrane
0.68	GO:0005881	cytoplasmic microtubule
0.66	GO:0072686	mitotic spindle
0.65	GO:0000777	condensed chromosome kinetochore
0.62	GO:0005815	microtubule organizing center
0.62	GO:0005829	cytosol
0.62	GO:0045180	basal cortex
0.61	GO:0030981	cortical microtubule cytoskeleton
0.61	GO:0044295	axonal growth cone

sp|Q6NYX6|CCNF_DANRE
Cyclin-F
Search

CCNF

0.97

Cyclin-F

0.72	GO:0051726	regulation of cell cycle
0.58	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.56	GO:0000320	re-entry into mitotic cell cycle
0.55	GO:0070507	regulation of microtubule cytoskeleton organization
0.55	GO:0051494	negative regulation of cytoskeleton organization
0.53	GO:0001890	placenta development
0.52	GO:0016567	protein ubiquitination
0.39	GO:0051301	cell division
0.35	GO:0043687	post-translational protein modification
0.35	GO:0055085	transmembrane transport

0.37	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0008144	drug binding
0.34	GO:0005515	protein binding
0.33	GO:0017127	cholesterol transporter activity
0.33	GO:0005543	phospholipid binding
0.32	GO:1901681	sulfur compound binding

0.60	GO:0005634	nucleus
0.57	GO:0019005	SCF ubiquitin ligase complex
0.57	GO:0005814	centriole
0.53	GO:0005813	centrosome
0.51	GO:0030054	cell junction
0.34	GO:0005829	cytosol
0.34	GO:0034359	mature chylomicron
0.33	GO:0034363	intermediate-density lipoprotein particle
0.33	GO:0034362	low-density lipoprotein particle
0.33	GO:0031983	vesicle lumen

0.37

GO:0004842

sp|Q6NYX8|PITH1_DANRE
PITH domain-containing protein 1
Search

PITHD1

0.96	PITH domain-containing protein 1

0.57	GO:0006974	cellular response to DNA damage stimulus
0.35	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0006414	translational elongation

0.35	GO:0003746	translation elongation factor activity
0.35	GO:0016787	hydrolase activity
0.34	GO:0003735	structural constituent of ribosome

0.55	GO:0005634	nucleus
0.55	GO:1905369	endopeptidase complex
0.47	GO:0043234	protein complex
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0005840	ribosome
0.34	GO:0044446	intracellular organelle part

0.35

GO:0016787

tr|Q6NYY3|Q6NYY3_DANRE
Potassium channel tetramerization domain-containing 5a
Search

KCTD5

0.91	Potassium channel tetramerisation domain containing 5

0.78	GO:0051260	protein homooligomerization
0.51	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

0.57	GO:0032403	protein complex binding
0.57	GO:0097602	cullin family protein binding
0.51	GO:0042802	identical protein binding

0.54	GO:0031463	Cul3-RING ubiquitin ligase complex
0.49	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q6NYY4|AS1BA_DANRE
Histone chaperone asf1b-A
Search

0.92	Anti-silencing function 1Ba histone chaperone

0.74	GO:0006333	chromatin assembly or disassembly
0.59	GO:0034728	nucleosome organization
0.58	GO:0065004	protein-DNA complex assembly
0.57	GO:0006323	DNA packaging
0.55	GO:0001649	osteoblast differentiation
0.53	GO:0042692	muscle cell differentiation
0.45	GO:0006281	DNA repair
0.45	GO:0016569	covalent chromatin modification
0.39	GO:0032986	protein-DNA complex disassembly
0.38	GO:0006351	transcription, DNA-templated

0.60	GO:0042393	histone binding
0.51	GO:0003682	chromatin binding

0.59	GO:0005634	nucleus
0.54	GO:0000785	chromatin
0.51	GO:0031974	membrane-enclosed lumen
0.47	GO:0043234	protein complex

sp|Q6NYY9|VMP1_DANRE
Vacuole membrane protein 1
Search

VMP1

0.96	Vacuole membrane protein 1

0.54	GO:0034329	cell junction assembly
0.53	GO:0007566	embryo implantation
0.51	GO:0006914	autophagy
0.51	GO:0098609	cell-cell adhesion
0.49	GO:0007030	Golgi organization
0.48	GO:0007029	endoplasmic reticulum organization
0.46	GO:0006887	exocytosis
0.36	GO:0015031	protein transport
0.36	GO:0002790	peptide secretion
0.34	GO:0048268	clathrin coat assembly

0.35	GO:0005515	protein binding
0.34	GO:0005198	structural molecule activity

0.56	GO:0000407	phagophore assembly site
0.51	GO:0005783	endoplasmic reticulum
0.49	GO:0005730	nucleolus
0.43	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.41	GO:0005774	vacuolar membrane
0.40	GO:0005776	autophagosome
0.36	GO:0005886	plasma membrane
0.34	GO:0071439	clathrin complex
0.34	GO:0030130	clathrin coat of trans-Golgi network vesicle
0.34	GO:0005905	clathrin-coated pit

sp|Q6NYZ4|PLA1A_DANRE
Phospholipase A1 member A
Search

PLA1A

0.96	Phospholipase A1 member A

0.58	GO:0006629	lipid metabolic process
0.36	GO:1901575	organic substance catabolic process
0.33	GO:0006575	cellular modified amino acid metabolic process
0.32	GO:0019637	organophosphate metabolic process
0.32	GO:0006796	phosphate-containing compound metabolic process

0.65	GO:0052689	carboxylic ester hydrolase activity
0.46	GO:0004620	phospholipase activity

0.62	GO:0005576	extracellular region
0.51	GO:0002080	acrosomal membrane
0.30	GO:0031224	intrinsic component of membrane

0.65	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.65	KEGG:R00630	GO:0052689

sp|Q6NYZ6|SCM2A_DANRE
Calcium-binding mitochondrial carrier protein SCaMC-2-A
Search

SLC25A25

0.54	Calcium-binding mitochondrial carrier protein SCaMC-2-A

0.55	GO:0055085	transmembrane transport
0.51	GO:0032094	response to food
0.51	GO:0002021	response to dietary excess
0.50	GO:0014823	response to activity
0.50	GO:0060612	adipose tissue development
0.49	GO:0035264	multicellular organism growth
0.48	GO:0043010	camera-type eye development
0.47	GO:0015866	ADP transport
0.46	GO:0015867	ATP transport
0.46	GO:0006816	calcium ion transport

0.70	GO:0005509	calcium ion binding
0.47	GO:0015217	ADP transmembrane transporter activity
0.47	GO:0005347	ATP transmembrane transporter activity

0.61	GO:0031966	mitochondrial membrane
0.61	GO:0019866	organelle inner membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

tr|Q6NZ01|Q6NZ01_DANRE
Bdnf protein
Search

BDNF

0.59	Brain-derived neurotrophic factor

0.76	GO:0010469	regulation of receptor activity
0.48	GO:0071542	dopaminergic neuron differentiation
0.47	GO:0033555	multicellular organismal response to stress
0.45	GO:0007420	brain development
0.37	GO:0043524	negative regulation of neuron apoptotic process
0.36	GO:0045664	regulation of neuron differentiation
0.36	GO:0048812	neuron projection morphogenesis
0.36	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.36	GO:0007267	cell-cell signaling

0.78	GO:0008083	growth factor activity
0.38	GO:0005169	neurotrophin TRKB receptor binding

0.66	GO:0005576	extracellular region
0.36	GO:0031410	cytoplasmic vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|Q6NZ03|FBSP1_DANRE
F-box/SPRY domain-containing protein 1
Search

FBXO45

0.70	F-box/SPRY domain-containing protein 1

0.75	GO:0045886	negative regulation of synaptic growth at neuromuscular junction
0.73	GO:0007274	neuromuscular synaptic transmission
0.73	GO:0016567	protein ubiquitination
0.70	GO:0007399	nervous system development
0.68	GO:0045732	positive regulation of protein catabolic process
0.58	GO:0010629	negative regulation of gene expression
0.56	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.55	GO:0050808	synapse organization
0.54	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.54	GO:0060322	head development

0.44	GO:0005515	protein binding
0.40	GO:0004842	ubiquitin-protein transferase activity

0.74	GO:0019005	SCF ubiquitin ligase complex
0.73	GO:0045495	pole plasm
0.72	GO:0031594	neuromuscular junction
0.69	GO:0030054	cell junction
0.65	GO:0005938	cell cortex
0.57	GO:0014069	postsynaptic density
0.54	GO:0042734	presynaptic membrane
0.54	GO:0005634	nucleus
0.51	GO:0045211	postsynaptic membrane
0.43	GO:0043204	perikaryon

0.40

GO:0004842

sp|Q6NZ04|SIX1B_DANRE
Homeobox protein six1b
Search

SIX1

0.96	SIX homeobox 1

0.74	GO:0072074	kidney mesenchyme development
0.73	GO:0042474	middle ear morphogenesis
0.73	GO:0008283	cell proliferation
0.73	GO:0090189	regulation of branching involved in ureteric bud morphogenesis
0.71	GO:0072088	nephron epithelium morphogenesis
0.71	GO:0001656	metanephros development
0.70	GO:0048701	embryonic cranial skeleton morphogenesis
0.69	GO:0001708	cell fate specification
0.67	GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development
0.67	GO:0030910	olfactory placode formation

0.68	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.66	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0003682	chromatin binding
0.50	GO:0032403	protein complex binding
0.50	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.56	GO:0005667	transcription factor complex
0.51	GO:0070013	intracellular organelle lumen
0.47	GO:0043232	intracellular non-membrane-bounded organelle
0.46	GO:0044446	intracellular organelle part

sp|Q6NZ06|ILF2_DANRE
Interleukin enhancer-binding factor 2 homolog
Search

ILF2

0.96	Interleukin enhancer binding factor 2

0.71	GO:0006955	immune response
0.47	GO:0045893	positive regulation of transcription, DNA-templated
0.41	GO:0006351	transcription, DNA-templated
0.35	GO:0002446	neutrophil mediated immunity
0.35	GO:0043299	leukocyte degranulation
0.35	GO:0042119	neutrophil activation

0.57	GO:0003723	RNA binding
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0016740	transferase activity
0.40	GO:0003677	DNA binding
0.34	GO:0005515	protein binding

0.48	GO:0005730	nucleolus
0.44	GO:0005576	extracellular region
0.42	GO:0030529	intracellular ribonucleoprotein complex
0.36	GO:1904724	tertiary granule lumen
0.36	GO:0035580	specific granule lumen
0.36	GO:1904813	ficolin-1-rich granule lumen
0.30	GO:0031224	intrinsic component of membrane

0.50

GO:0016740

sp|Q6NZ07|NCLN_DANRE
Nicalin-1
Search

NCLN

0.92

Nicalin

0.64	GO:0009966	regulation of signal transduction
0.53	GO:0031648	protein destabilization
0.48	GO:2000381	negative regulation of mesoderm development
0.47	GO:0048484	enteric nervous system development
0.46	GO:0043254	regulation of protein complex assembly
0.44	GO:0051241	negative regulation of multicellular organismal process
0.43	GO:2000026	regulation of multicellular organismal development
0.43	GO:0023057	negative regulation of signaling
0.43	GO:0010648	negative regulation of cell communication
0.42	GO:0048585	negative regulation of response to stimulus

0.35	GO:0004177	aminopeptidase activity
0.34	GO:0003713	transcription coactivator activity
0.33	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.52	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:3.4.11

GO:0004177

sp|Q6NZ09|ADRM1_DANRE
Proteasomal ubiquitin receptor ADRM1
Search

ADRM1

0.90	Adhesion-regulating molecule 1

0.54	GO:0010950	positive regulation of endopeptidase activity
0.52	GO:0043248	proteasome assembly
0.50	GO:0006368	transcription elongation from RNA polymerase II promoter
0.43	GO:0006511	ubiquitin-dependent protein catabolic process
0.37	GO:0060399	positive regulation of growth hormone receptor signaling pathway
0.37	GO:0060009	Sertoli cell development
0.37	GO:0072520	seminiferous tubule development
0.37	GO:0033081	regulation of T cell differentiation in thymus
0.37	GO:0042699	follicle-stimulating hormone signaling pathway
0.37	GO:0060612	adipose tissue development

0.57	GO:0061133	endopeptidase activator activity
0.54	GO:0070628	proteasome binding
0.52	GO:0002020	protease binding
0.45	GO:0043130	ubiquitin binding

0.61	GO:0005634	nucleus
0.50	GO:1905369	endopeptidase complex
0.49	GO:0005737	cytoplasm
0.45	GO:0043233	organelle lumen
0.44	GO:0043234	protein complex
0.41	GO:0044446	intracellular organelle part
0.40	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q6NZ13|NBL1_DANRE
Neuroblastoma suppressor of tumorigenicity 1
Search

NBL1

0.97	Neuroblastoma suppressor of tumorigenicity 1

0.70	GO:0090027	negative regulation of monocyte chemotaxis
0.70	GO:0048263	determination of dorsal identity
0.69	GO:0035582	sequestering of BMP in extracellular matrix
0.62	GO:0045666	positive regulation of neuron differentiation
0.61	GO:0048812	neuron projection morphogenesis
0.60	GO:0010469	regulation of receptor activity
0.47	GO:0048752	semicircular canal morphogenesis
0.46	GO:0038098	sequestering of BMP from receptor via BMP binding
0.42	GO:0035148	tube formation

0.69	GO:0016015	morphogen activity
0.67	GO:0036122	BMP binding
0.43	GO:0042803	protein homodimerization activity
0.42	GO:0005125	cytokine activity

0.65	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q6NZ18|K0907_DANRE
UPF0469 protein KIAA0907 homolog
Search

KHDC4

0.96	KH homology domain-containing protein 4

0.78

GO:0006376

mRNA splice site selection

0.59	GO:0003723	RNA binding
0.50	GO:0005515	protein binding

0.72	GO:0005681	spliceosomal complex
0.48	GO:0019013	viral nucleocapsid
0.47	GO:0005737	cytoplasm

sp|Q6NZ21|RNFT1_DANRE
RING finger and transmembrane domain-containing protein 1
Search

RNFT1

0.97	RING finger and transmembrane domain-containing protein 1

0.39	GO:0016567	protein ubiquitination
0.32	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.31	GO:0098655	cation transmembrane transport

0.35	GO:0046872	metal ion binding
0.35	GO:0016740	transferase activity
0.33	GO:0016874	ligase activity
0.33	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0031624	ubiquitin conjugating enzyme binding
0.31	GO:0008324	cation transmembrane transporter activity

0.38	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0031901	early endosome membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0016740

sp|Q6NZ22|MET14_DANRE
N6-adenosine-methyltransferase subunit METTL14
Search

METTL14

0.97	N6-adenosine-methyltransferase non-catalytic subunit

0.61	GO:0021861	forebrain radial glial cell differentiation
0.61	GO:0032259	methylation
0.59	GO:0061157	mRNA destabilization
0.57	GO:0016556	mRNA modification
0.57	GO:0019827	stem cell population maintenance
0.55	GO:0007283	spermatogenesis
0.53	GO:0000398	mRNA splicing, via spliceosome
0.51	GO:0006402	mRNA catabolic process
0.41	GO:0030237	female sex determination
0.40	GO:0000381	regulation of alternative mRNA splicing, via spliceosome

0.61	GO:0008168	methyltransferase activity
0.53	GO:0003729	mRNA binding
0.47	GO:0140098	catalytic activity, acting on RNA
0.43	GO:1904047	S-adenosyl-L-methionine binding
0.34	GO:0005515	protein binding

0.62	GO:0036396	RNA N6-methyladenosine methyltransferase complex
0.49	GO:0005654	nucleoplasm
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.61

GO:0008168

tr|Q6NZ31|Q6NZ31_DANRE
Cyclin G2
Search

0.73	GO:0051726	regulation of cell cycle
0.34	GO:0051301	cell division
0.34	GO:0007049	cell cycle

0.34	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.33	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.34

EC:2.8.2.8

GO:0015016

tr|Q6NZ32|Q6NZ32_DANRE
Flavin-containing monooxygenase
Search

0.60	Flavin-containing monooxygenase

0.53	GO:0055114	oxidation-reduction process
0.41	GO:0071466	cellular response to xenobiotic stimulus
0.35	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.34	GO:0007165	signal transduction
0.33	GO:0006468	protein phosphorylation
0.32	GO:0016042	lipid catabolic process
0.32	GO:0045454	cell redox homeostasis

0.78	GO:0004499	N,N-dimethylaniline monooxygenase activity
0.70	GO:0050661	NADP binding
0.66	GO:0050660	flavin adenine dinucleotide binding
0.36	GO:0001104	RNA polymerase II transcription cofactor activity
0.34	GO:0005549	odorant binding
0.34	GO:0004984	olfactory receptor activity
0.33	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding

0.36	GO:0016592	mediator complex
0.30	GO:0016020	membrane

0.78

EC:1.14.13.8

GO:0004499

tr|Q6NZ72|Q6NZ72_DANRE
Aquaporin 1a
Search

0.54	Aquaporin FA-CHIP

0.57	GO:0006833	water transport
0.56	GO:0035378	carbon dioxide transmembrane transport
0.55	GO:0085018	maintenance of symbiont-containing vacuole by host
0.54	GO:0072230	metanephric proximal straight tubule development
0.54	GO:0072232	metanephric proximal convoluted tubule segment 2 development
0.54	GO:0072220	metanephric descending thin limb development
0.53	GO:0003091	renal water homeostasis
0.53	GO:0051458	corticotropin secretion
0.53	GO:0021670	lateral ventricle development
0.52	GO:0072239	metanephric glomerulus vasculature development

0.69	GO:0015267	channel activity
0.57	GO:0005372	water transmembrane transporter activity
0.56	GO:0035379	carbon dioxide transmembrane transporter activity
0.50	GO:0046875	ephrin receptor binding
0.49	GO:0008519	ammonium transmembrane transporter activity
0.47	GO:0015079	potassium ion transmembrane transporter activity
0.46	GO:0030184	nitric oxide transmembrane transporter activity
0.44	GO:0015168	glycerol transmembrane transporter activity
0.38	GO:0042802	identical protein binding

0.52	GO:0016323	basolateral plasma membrane
0.52	GO:0020003	symbiont-containing vacuole
0.52	GO:0045178	basal part of cell
0.52	GO:0005903	brush border
0.51	GO:0016324	apical plasma membrane
0.49	GO:0005901	caveola
0.49	GO:0070062	extracellular exosome
0.48	GO:0030424	axon
0.43	GO:0031253	cell projection membrane
0.43	GO:0042383	sarcolemma

tr|Q6NZS2|Q6NZS2_DANRE
Zgc:65895
Search

TSC22D1

0.37	Putative transcriptional regulator

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.37	GO:0006970	response to osmotic stress
0.35	GO:0008284	positive regulation of cell proliferation
0.35	GO:0043065	positive regulation of apoptotic process
0.35	GO:0043066	negative regulation of apoptotic process
0.35	GO:0006351	transcription, DNA-templated
0.33	GO:1902680	positive regulation of RNA biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.34	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.33	GO:0005515	protein binding

0.39	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

sp|Q6NZS4|RTCB_DANRE
tRNA-splicing ligase RtcB homolog
Search

RTCB

0.87	tRNA-splicing ligase RtcB homolog

0.79	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.50	GO:0001890	placenta development
0.49	GO:0001701	in utero embryonic development
0.38	GO:0030969	mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response
0.38	GO:0000378	RNA exon ligation
0.38	GO:0040025	vulval development
0.36	GO:0007281	germ cell development
0.33	GO:0006281	DNA repair

0.84	GO:0003972	RNA ligase (ATP) activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0017166	vinculin binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0046872	metal ion binding
0.35	GO:0008289	lipid binding
0.34	GO:0003676	nucleic acid binding
0.33	GO:0008094	DNA-dependent ATPase activity

0.85	GO:0072669	tRNA-splicing ligase complex
0.46	GO:0005635	nuclear envelope
0.45	GO:0005789	endoplasmic reticulum membrane
0.44	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:6.5.1.3

GO:0003972

sp|Q6NZT2|CDR2L_DANRE
Cerebellar degeneration-related protein 2-like
Search

CDR2L

0.94	Cerebellar degeneration related protein 2 like

0.46	GO:0006415	translational termination
0.38	GO:0006457	protein folding

0.46	GO:0003747	translation release factor activity
0.42	GO:0005515	protein binding

0.44

GO:0005737

cytoplasm

tr|Q6NZT5|Q6NZT5_DANRE
Jun proto-oncogene
Search

JUN

0.93	Transcription factor jun-B

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0046686	response to cadmium ion
0.51	GO:0009612	response to mechanical stimulus
0.51	GO:0035026	leading edge cell differentiation
0.50	GO:0001774	microglial cell activation
0.50	GO:0061029	eyelid development in camera-type eye
0.50	GO:0031953	negative regulation of protein autophosphorylation
0.50	GO:0030224	monocyte differentiation

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.49	GO:0003713	transcription coactivator activity
0.49	GO:0001067	regulatory region nucleic acid binding
0.49	GO:0070412	R-SMAD binding
0.48	GO:0001102	RNA polymerase II activating transcription factor binding
0.46	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0003682	chromatin binding
0.45	GO:0008013	beta-catenin binding
0.45	GO:0005096	GTPase activator activity

0.51	GO:0005667	transcription factor complex
0.48	GO:0005719	nuclear euchromatin
0.47	GO:0017053	transcriptional repressor complex
0.43	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.33	GO:0042025	host cell nucleus
0.33	GO:0032993	protein-DNA complex
0.30	GO:0016020	membrane

sp|Q6NZT6|I2B2A_DANRE
Interferon regulatory factor 2-binding protein 2-A
Search

0.88	Interferon regulatory factor 2-binding protein 2-A

0.58	GO:0000122	negative regulation of transcription by RNA polymerase II
0.56	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:0006351	transcription, DNA-templated
0.42	GO:0046543	development of secondary female sexual characteristics

0.50	GO:0046872	metal ion binding
0.37	GO:0003714	transcription corepressor activity

0.58	GO:0005634	nucleus
0.53	GO:0031974	membrane-enclosed lumen
0.47	GO:0044446	intracellular organelle part
0.38	GO:0005615	extracellular space
0.33	GO:0005737	cytoplasm

tr|Q6NZT9|Q6NZT9_DANRE
Serine/arginine-rich-splicing factor 2b
Search

SRSF2

0.93	Serine and arginine rich splicing factor 2

0.77	GO:0043484	regulation of RNA splicing
0.45	GO:0050684	regulation of mRNA processing
0.41	GO:0033197	response to vitamin E
0.40	GO:0008380	RNA splicing
0.39	GO:0006397	mRNA processing
0.37	GO:0000278	mitotic cell cycle
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0001178	regulation of transcriptional start site selection at RNA polymerase II promoter
0.34	GO:0031123	RNA 3'-end processing

0.59	GO:0003723	RNA binding
0.40	GO:0005080	protein kinase C binding
0.34	GO:0003714	transcription corepressor activity
0.34	GO:0004623	phospholipase A2 activity

0.49	GO:0016607	nuclear speck
0.45	GO:0005681	spliceosomal complex
0.44	GO:0005829	cytosol
0.40	GO:0035061	interchromatin granule
0.37	GO:0016605	PML body
0.36	GO:0070062	extracellular exosome
0.33	GO:0000785	chromatin
0.33	GO:0019013	viral nucleocapsid
0.30	GO:0016020	membrane

0.34

EC:3.1.1.4

GO:0004623

tr|Q6NZU0|Q6NZU0_DANRE
Heat shock protein 4
Search

0.90	Heat shock protein 4

0.53	GO:0045040	protein import into mitochondrial outer membrane
0.52	GO:0051131	chaperone-mediated protein complex assembly
0.34	GO:0043392	negative regulation of DNA binding
0.34	GO:0032092	positive regulation of protein binding
0.34	GO:0045766	positive regulation of angiogenesis
0.34	GO:0006986	response to unfolded protein
0.34	GO:0001822	kidney development
0.34	GO:0043066	negative regulation of apoptotic process
0.34	GO:0009408	response to heat
0.34	GO:0001933	negative regulation of protein phosphorylation

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.33	GO:0044877	macromolecular complex binding
0.32	GO:0046872	metal ion binding

0.51	GO:0070062	extracellular exosome
0.46	GO:0005829	cytosol
0.34	GO:0005811	lipid droplet
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|Q6NZU4|Q6NZU4_DANRE
Iroquois homeobox 4a
Search

0.87	Iroquois homeobox 4

0.64	GO:0048888	neuromast mantle cell differentiation
0.61	GO:0048923	posterior lateral line neuromast hair cell differentiation
0.57	GO:0042461	photoreceptor cell development
0.57	GO:0007507	heart development
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.39	GO:0048561	establishment of animal organ orientation

0.65

GO:0043565

sequence-specific DNA binding

0.61

GO:0005634

nucleus

tr|Q6NZV1|Q6NZV1_DANRE
3-phosphoinositide-dependent protein kinase 1b
Search

PDPK1

0.90	Phosphoinositide-dependent protein kinase-1 beta

0.63	GO:0006468	protein phosphorylation
0.56	GO:1905564	positive regulation of vascular endothelial cell proliferation
0.55	GO:0032148	activation of protein kinase B activity
0.55	GO:0071364	cellular response to epidermal growth factor stimulus
0.55	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.55	GO:0010518	positive regulation of phospholipase activity
0.54	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.54	GO:1903078	positive regulation of protein localization to plasma membrane
0.54	GO:0007173	epidermal growth factor receptor signaling pathway
0.54	GO:0097191	extrinsic apoptotic signaling pathway

0.64	GO:0004672	protein kinase activity
0.56	GO:0016004	phospholipase activator activity
0.56	GO:0043274	phospholipase binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.38	GO:0005158	insulin receptor binding
0.37	GO:0019901	protein kinase binding

0.49	GO:0014069	postsynaptic density
0.46	GO:0042995	cell projection
0.45	GO:0031410	cytoplasmic vesicle
0.41	GO:0005886	plasma membrane
0.38	GO:0043204	perikaryon
0.37	GO:0005925	focal adhesion
0.36	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part

tr|Q6NZV2|Q6NZV2_DANRE
DNA helicase
Search

MCM4

0.44	DNA helicase

0.74	GO:0006270	DNA replication initiation
0.69	GO:0032392	DNA geometric change
0.47	GO:0001878	response to yeast

0.69	GO:0003678	DNA helicase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0003677	DNA binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0070035	purine NTP-dependent helicase activity
0.46	GO:0008094	DNA-dependent ATPase activity
0.43	GO:0003682	chromatin binding

0.78	GO:0042555	MCM complex
0.60	GO:0005634	nucleus
0.45	GO:0031974	membrane-enclosed lumen
0.41	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome
0.30	GO:0016020	membrane

tr|Q6NZV4|Q6NZV4_DANRE
Cysteine and glycine-rich protein 1
Search

CSRP1

0.87	Four and a half LIM domains protein 2

0.42	GO:0031102	neuron projection regeneration
0.42	GO:0060027	convergent extension involved in gastrulation
0.42	GO:0042074	cell migration involved in gastrulation
0.41	GO:0007254	JNK cascade
0.41	GO:0003007	heart morphogenesis
0.40	GO:0016055	Wnt signaling pathway
0.36	GO:0070527	platelet aggregation
0.34	GO:0045445	myoblast differentiation
0.34	GO:0006937	regulation of muscle contraction
0.34	GO:0030036	actin cytoskeleton organization

0.54	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.51	GO:0097517	contractile actin filament bundle
0.51	GO:0042641	actomyosin
0.50	GO:0005925	focal adhesion
0.49	GO:0031252	cell leading edge
0.43	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.33	GO:0099512	supramolecular fiber
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0043234	protein complex

sp|Q6NZW0|C102A_DANRE
Coiled-coil domain-containing protein 102A
Search

CCDC102A

0.94	Coiled-coil domain-containing protein 102A

0.72

GO:0003774

motor activity

0.76

GO:0016459

myosin complex

tr|Q6NZW3|Q6NZW3_DANRE
Cofilin 2 (Muscle)
Search

CFL2

0.96	Cofilin 2 (Muscle)

0.84	GO:0030042	actin filament depolymerization
0.58	GO:0030836	positive regulation of actin filament depolymerization
0.55	GO:0046716	muscle cell cellular homeostasis
0.54	GO:0045214	sarcomere organization
0.53	GO:0007519	skeletal muscle tissue development
0.46	GO:0001842	neural fold formation
0.45	GO:0001755	neural crest cell migration
0.45	GO:0044794	positive regulation by host of viral process
0.44	GO:0061001	regulation of dendritic spine morphogenesis
0.44	GO:0043200	response to amino acid

0.74	GO:0003779	actin binding
0.54	GO:0032403	protein complex binding
0.41	GO:0005102	receptor binding
0.37	GO:0019903	protein phosphatase binding
0.37	GO:1902936	phosphatidylinositol bisphosphate binding
0.34	GO:0046872	metal ion binding

0.74	GO:0015629	actin cytoskeleton
0.53	GO:0030018	Z disc
0.45	GO:0030027	lamellipodium
0.45	GO:0016363	nuclear matrix
0.43	GO:0030863	cortical cytoskeleton
0.42	GO:0005615	extracellular space
0.42	GO:0005911	cell-cell junction
0.40	GO:0032587	ruffle membrane
0.40	GO:0044430	cytoskeletal part
0.38	GO:1903561	extracellular vesicle

sp|Q6NZW8|AR8BA_DANRE
ADP-ribosylation factor-like protein 8B-A
Search

ARL8B

0.92	ADP ribosylation factor like GTPase 8B

0.54	GO:0032418	lysosome localization
0.48	GO:0007059	chromosome segregation
0.37	GO:0051301	cell division
0.37	GO:0007049	cell cycle

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0043014	alpha-tubulin binding
0.52	GO:0048487	beta-tubulin binding
0.33	GO:0003924	GTPase activity

0.53	GO:0005765	lysosomal membrane
0.52	GO:0051233	spindle midzone
0.51	GO:0030496	midbody
0.41	GO:0031902	late endosome membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

tr|Q6NZW9|Q6NZW9_DANRE
Maf protein
Search

0.94	Basic domain leucine zipper transcription factor

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0006351	transcription, DNA-templated
0.52	GO:0048839	inner ear development
0.51	GO:0021598	abducens nerve morphogenesis
0.51	GO:0021572	rhombomere 6 development
0.50	GO:0035283	central nervous system segmentation
0.50	GO:0021571	rhombomere 5 development
0.50	GO:0045647	negative regulation of erythrocyte differentiation

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.46	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0008134	transcription factor binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity
0.33	GO:0003735	structural constituent of ribosome

0.61	GO:0005634	nucleus
0.44	GO:0005667	transcription factor complex
0.36	GO:0005737	cytoplasm
0.34	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0042025	host cell nucleus
0.32	GO:0030529	intracellular ribonucleoprotein complex

tr|Q6NZZ1|Q6NZZ1_DANRE
Zgc:77938
Search

0.40	Alcohol dehydrogenase Class VI

0.64	GO:0006067	ethanol metabolic process
0.53	GO:0055114	oxidation-reduction process
0.40	GO:0018119	peptidyl-cysteine S-nitrosylation
0.40	GO:0003016	respiratory system process
0.40	GO:0045777	positive regulation of blood pressure
0.39	GO:0001523	retinoid metabolic process
0.39	GO:0046292	formaldehyde metabolic process
0.39	GO:0051409	response to nitrosative stress
0.39	GO:0032496	response to lipopolysaccharide
0.39	GO:0051775	response to redox state

0.63	GO:0051903	S-(hydroxymethyl)glutathione dehydrogenase activity
0.63	GO:0008270	zinc ion binding
0.44	GO:0004022	alcohol dehydrogenase (NAD) activity
0.41	GO:0018467	formaldehyde dehydrogenase activity
0.40	GO:0005504	fatty acid binding
0.38	GO:0042803	protein homodimerization activity
0.34	GO:0005044	scavenger receptor activity

0.35	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.63	EC:1.1.1.284	GO:0051903
0.63	KEGG:R06983 KEGG:R07140	GO:0051903

sp|Q6NZZ3|CF120_DANRE
UPF0669 protein C6orf120 homolog
Search

0.63	GO:0006915	apoptotic process
0.49	GO:0043312	neutrophil degranulation
0.40	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.41

GO:0004519

endonuclease activity

0.63	GO:0005576	extracellular region
0.50	GO:0035578	azurophil granule lumen
0.30	GO:0016020	membrane

sp|Q6NZZ4|TM107_DANRE
Transmembrane protein 107
Search

TMEM107

0.54	Transmembrane protein 107 like

0.59	GO:1904491	protein localization to ciliary transition zone
0.57	GO:0021532	neural tube patterning
0.56	GO:0042733	embryonic digit morphogenesis
0.56	GO:1905515	non-motile cilium assembly

0.34

GO:0005515

protein binding

0.57	GO:0036038	MKS complex
0.30	GO:0044425	membrane part

tr|Q6NZZ8|Q6NZZ8_DANRE
Chitinase, acidic.3
Search

0.45	Eosinophil chemotactic cytokine

0.74	GO:0006030	chitin metabolic process
0.60	GO:0005975	carbohydrate metabolic process
0.49	GO:1901072	glucosamine-containing compound catabolic process
0.46	GO:0006026	aminoglycan catabolic process
0.45	GO:0042737	drug catabolic process
0.35	GO:0044245	polysaccharide digestion
0.34	GO:0043312	neutrophil degranulation
0.34	GO:0009617	response to bacterium

0.77	GO:0008061	chitin binding
0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.64	GO:0005576	extracellular region
0.35	GO:1904724	tertiary granule lumen
0.35	GO:0035580	specific granule lumen
0.34	GO:0005764	lysosome
0.30	GO:0016020	membrane

0.66

GO:0004553

sp|Q6NZZ9|RBM22_DANRE
Pre-mRNA-splicing factor RBM22
Search

RBM22

0.93	RNA binding motif protein 22

0.66	GO:0000060	protein import into nucleus, translocation
0.66	GO:0033120	positive regulation of RNA splicing
0.65	GO:0046827	positive regulation of protein export from nucleus
0.64	GO:0042307	positive regulation of protein import into nucleus
0.63	GO:0045292	mRNA cis splicing, via spliceosome
0.62	GO:0035690	cellular response to drug
0.52	GO:0000387	spliceosomal snRNP assembly
0.50	GO:0043009	chordate embryonic development

0.68	GO:0017070	U6 snRNA binding
0.67	GO:0036002	pre-mRNA binding
0.65	GO:0048306	calcium-dependent protein binding
0.54	GO:0046872	metal ion binding

0.68	GO:0071007	U2-type catalytic step 2 spliceosome
0.55	GO:0071006	U2-type catalytic step 1 spliceosome
0.54	GO:0000974	Prp19 complex
0.42	GO:0005737	cytoplasm

tr|Q6P001|Q6P001_DANRE
Dehydrogenase/reductase (SDR family) member 13-like 1
Search

0.74	Retinol dehydrogenase 11

0.39	GO:0055114	oxidation-reduction process
0.36	GO:0042572	retinol metabolic process

0.40	GO:0016491	oxidoreductase activity
0.35	GO:0003723	RNA binding
0.33	GO:0046872	metal ion binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.32	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

0.40

GO:0016491

tr|Q6P005|Q6P005_DANRE
Tescalcin b
Search

TESC

0.97	Calcineurin B ous protein 3

0.50	GO:0032417	positive regulation of sodium:proton antiporter activity
0.49	GO:0030854	positive regulation of granulocyte differentiation
0.48	GO:0071300	cellular response to retinoic acid
0.47	GO:0072659	protein localization to plasma membrane
0.46	GO:0045654	positive regulation of megakaryocyte differentiation
0.46	GO:0050821	protein stabilization
0.45	GO:0033628	regulation of cell adhesion mediated by integrin
0.43	GO:0051604	protein maturation
0.43	GO:0008285	negative regulation of cell proliferation
0.42	GO:0045893	positive regulation of transcription, DNA-templated

0.70	GO:0005509	calcium ion binding
0.43	GO:0019212	phosphatase inhibitor activity
0.41	GO:0042803	protein homodimerization activity
0.41	GO:0004860	protein kinase inhibitor activity
0.39	GO:0000287	magnesium ion binding
0.34	GO:0003677	DNA binding

0.47	GO:0030027	lamellipodium
0.43	GO:0001726	ruffle
0.41	GO:0031256	leading edge membrane
0.41	GO:0031253	cell projection membrane
0.40	GO:0005634	nucleus
0.40	GO:0005829	cytosol

tr|Q6P006|Q6P006_DANRE
Chitinase, acidic.2
Search

0.45	Eosinophil chemotactic cytokine

0.75	GO:0006030	chitin metabolic process
0.60	GO:0005975	carbohydrate metabolic process
0.48	GO:1901072	glucosamine-containing compound catabolic process
0.46	GO:0006026	aminoglycan catabolic process
0.45	GO:0042737	drug catabolic process

0.77	GO:0008061	chitin binding
0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.64	GO:0005576	extracellular region
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.66

GO:0004553

tr|Q6P009|Q6P009_DANRE
D-amino-acid oxidase 3
Search

DAO

0.61	Peroxisomal sarcosine oxidase

0.76	GO:0046416	D-amino acid metabolic process
0.57	GO:0042416	dopamine biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0009080	pyruvate family amino acid catabolic process
0.52	GO:0006562	proline catabolic process
0.52	GO:0046144	D-alanine family amino acid metabolic process
0.50	GO:0009071	serine family amino acid catabolic process
0.48	GO:0042737	drug catabolic process
0.35	GO:0006551	leucine metabolic process
0.32	GO:0034641	cellular nitrogen compound metabolic process

0.83	GO:0003884	D-amino-acid oxidase activity
0.73	GO:0071949	FAD binding
0.49	GO:0005102	receptor binding
0.47	GO:0046983	protein dimerization activity
0.35	GO:0015922	aspartate oxidase activity

0.52	GO:0005777	peroxisome
0.52	GO:0031903	microbody membrane
0.51	GO:0005741	mitochondrial outer membrane
0.47	GO:0005829	cytosol
0.35	GO:0031907	microbody lumen
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:1.4.3.3

GO:0003884

sp|Q6P011|EMC4_DANRE
ER membrane protein complex subunit 4
Search

EMC4

0.76	ER membrane protein complex subunit 4

0.49	GO:0034975	protein folding in endoplasmic reticulum
0.38	GO:0006915	apoptotic process
0.36	GO:0006508	proteolysis
0.34	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
0.34	GO:0008217	regulation of blood pressure
0.33	GO:0031929	TOR signaling

0.36	GO:0004252	serine-type endopeptidase activity
0.34	GO:0070006	metalloaminopeptidase activity
0.33	GO:0008270	zinc ion binding

0.56	GO:0072546	ER membrane protein complex
0.33	GO:0031932	TORC2 complex

0.36

GO:0004252

tr|Q6P013|Q6P013_DANRE
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor
Search

TAF12

0.89	transcription initiation factor TFIID subunit 12

0.69	GO:0006352	DNA-templated transcription, initiation
0.59	GO:0006413	translational initiation
0.56	GO:0043966	histone H3 acetylation
0.52	GO:0006366	transcription by RNA polymerase II
0.50	GO:0051091	positive regulation of DNA binding transcription factor activity
0.46	GO:0065004	protein-DNA complex assembly
0.35	GO:1901796	regulation of signal transduction by p53 class mediator
0.34	GO:0006354	DNA-templated transcription, elongation

0.74	GO:0046982	protein heterodimerization activity
0.59	GO:0003743	translation initiation factor activity
0.54	GO:0004402	histone acetyltransferase activity
0.50	GO:0008134	transcription factor binding
0.49	GO:0003713	transcription coactivator activity
0.42	GO:0003700	DNA binding transcription factor activity
0.42	GO:0003677	DNA binding

0.82	GO:0046695	SLIK (SAGA-like) complex
0.80	GO:0000124	SAGA complex
0.80	GO:0005669	transcription factor TFIID complex
0.54	GO:0030914	STAGA complex
0.53	GO:0033276	transcription factor TFTC complex
0.40	GO:0000125	PCAF complex
0.30	GO:0016020	membrane

0.54

GO:0004402

tr|Q6P015|Q6P015_DANRE
Upstream transcription factor 1,-like
Search

0.88	Upstream transcription factor 2, c-fos interacting

0.46	GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose
0.45	GO:0019086	late viral transcription
0.43	GO:0055088	lipid homeostasis
0.43	GO:0009411	response to UV
0.42	GO:0032869	cellular response to insulin stimulus
0.42	GO:0001666	response to hypoxia
0.40	GO:0006366	transcription by RNA polymerase II
0.34	GO:0006265	DNA topological change
0.33	GO:0006006	glucose metabolic process
0.32	GO:0007165	signal transduction

0.68	GO:0046983	protein dimerization activity
0.43	GO:0043425	bHLH transcription factor binding
0.43	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.43	GO:0042826	histone deacetylase binding
0.41	GO:0019901	protein kinase binding
0.41	GO:0042802	identical protein binding
0.38	GO:0043565	sequence-specific DNA binding
0.34	GO:0061505	DNA topoisomerase II activity
0.34	GO:0008094	DNA-dependent ATPase activity
0.33	GO:0003690	double-stranded DNA binding

0.42	GO:0016589	NURF complex
0.42	GO:0048188	Set1C/COMPASS complex
0.40	GO:0005667	transcription factor complex

tr|Q6P016|Q6P016_DANRE
Purine nucleoside phosphorylase
Search

0.47	Purine nucleoside phosphorylase

0.66	GO:0009116	nucleoside metabolic process
0.39	GO:0034418	urate biosynthetic process
0.39	GO:0070970	interleukin-2 secretion
0.39	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway
0.38	GO:0046638	positive regulation of alpha-beta T cell differentiation
0.38	GO:0042102	positive regulation of T cell proliferation
0.38	GO:0072526	pyridine-containing compound catabolic process
0.37	GO:1901658	glycosyl compound catabolic process
0.37	GO:0072523	purine-containing compound catabolic process
0.36	GO:0006955	immune response

0.78	GO:0004731	purine-nucleoside phosphorylase activity
0.39	GO:0002060	purine nucleobase binding
0.37	GO:0042301	phosphate ion binding
0.35	GO:0001882	nucleoside binding
0.34	GO:0008144	drug binding

0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.78

EC:2.4.2.1

GO:0004731

tr|Q6P018|Q6P018_DANRE
Testis-expressed 264a
Search

TEX264

0.97	Testis-expressed protein 264

0.43	GO:0002576	platelet degranulation
0.43	GO:0007186	G-protein coupled receptor signaling pathway

0.43	GO:0004930	G-protein coupled receptor activity
0.41	GO:0004386	helicase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0005515	protein binding

0.46	GO:0070062	extracellular exosome
0.44	GO:0031093	platelet alpha granule lumen
0.38	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q6P021|Q6P021_DANRE
Growth arrest and DNA damage 45 gamma
Search

GADD45G

0.95	Growth arrest and DNA damage-inducible gamma

0.73	GO:0051726	regulation of cell cycle
0.62	GO:0006950	response to stress
0.58	GO:0000185	activation of MAPKKK activity
0.56	GO:1900745	positive regulation of p38MAPK cascade
0.54	GO:0046330	positive regulation of JNK cascade
0.51	GO:0043065	positive regulation of apoptotic process
0.46	GO:0000186	activation of MAPKK activity
0.45	GO:0006469	negative regulation of protein kinase activity
0.40	GO:0051597	response to methylmercury
0.40	GO:0001756	somitogenesis

0.34	GO:0005515	protein binding
0.33	GO:0017056	structural constituent of nuclear pore

0.61	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0012505	endomembrane system
0.32	GO:0031967	organelle envelope
0.32	GO:0043234	protein complex

tr|Q6P023|Q6P023_DANRE
Mitogen-activated protein kinase
Search

MAPK1

0.58	Mitogen-activated protein kinase

0.80	GO:0000165	MAPK cascade
0.55	GO:0019858	cytosine metabolic process
0.54	GO:0060440	trachea formation
0.54	GO:0042473	outer ear morphogenesis
0.54	GO:0061308	cardiac neural crest cell development involved in heart development
0.54	GO:0060020	Bergmann glial cell differentiation
0.54	GO:1903351	cellular response to dopamine
0.54	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.53	GO:0070849	response to epidermal growth factor
0.53	GO:1904355	positive regulation of telomere capping

0.82	GO:0004707	MAP kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0004708	MAP kinase kinase activity
0.52	GO:0001784	phosphotyrosine residue binding
0.51	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.50	GO:0019902	phosphatase binding
0.47	GO:0042802	identical protein binding

0.53	GO:0031143	pseudopodium
0.48	GO:0005901	caveola
0.47	GO:0005829	cytosol
0.46	GO:0005925	focal adhesion
0.46	GO:0005770	late endosome
0.46	GO:0005769	early endosome
0.44	GO:0005634	nucleus
0.44	GO:0005739	mitochondrion
0.43	GO:0005794	Golgi apparatus
0.43	GO:0005856	cytoskeleton

0.82	EC:2.7.11.24	GO:0004707
0.82	KEGG:R00162	GO:0004707

tr|Q6P025|Q6P025_DANRE
Gnb3 protein
Search

GNB3

0.94	Guanine nucleotide-binding protein beta subunit

0.61	GO:0007165	signal transduction
0.35	GO:0065009	regulation of molecular function
0.35	GO:0071377	cellular response to glucagon stimulus
0.33	GO:0006457	protein folding

0.50	GO:0051020	GTPase binding
0.42	GO:0032403	protein complex binding
0.37	GO:0030507	spectrin binding
0.37	GO:0005246	calcium channel regulator activity
0.37	GO:0004871	signal transducer activity
0.36	GO:0003924	GTPase activity

0.50	GO:0030425	dendrite
0.43	GO:0043209	myelin sheath
0.43	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0044297	cell body
0.37	GO:1905360	GTPase complex
0.37	GO:0070062	extracellular exosome
0.36	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.36	GO:0005765	lysosomal membrane
0.36	GO:0005925	focal adhesion
0.35	GO:0043234	protein complex

sp|Q6P026|BAF_DANRE
Barrier-to-autointegration factor
Search

BANF1

0.95	Barrier-to-autointegration factor B

0.50	GO:0045071	negative regulation of viral genome replication
0.35	GO:0075713	establishment of integrated proviral latency
0.35	GO:0015074	DNA integration
0.35	GO:0007077	mitotic nuclear envelope disassembly
0.35	GO:0010951	negative regulation of endopeptidase activity
0.35	GO:0007084	mitotic nuclear envelope reassembly
0.34	GO:0051169	nuclear transport
0.34	GO:0009615	response to virus

0.55	GO:0003677	DNA binding
0.54	GO:0097726	LEM domain binding
0.50	GO:0047485	protein N-terminus binding
0.49	GO:0008022	protein C-terminus binding
0.46	GO:0042803	protein homodimerization activity
0.45	GO:0019899	enzyme binding
0.36	GO:0004869	cysteine-type endopeptidase inhibitor activity

0.44	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.39	GO:0005635	nuclear envelope
0.38	GO:0005694	chromosome
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

tr|Q6P027|Q6P027_DANRE
Cellular retinaldehyde-binding protein b
Search

0.95	Retinaldehyde binding protein 1

0.78	GO:0007601	visual perception
0.62	GO:0007634	optokinetic behavior

0.86

GO:0016918

retinal binding

0.39

GO:0044297

cell body

tr|Q6P031|Q6P031_DANRE
Tetraspanin
Search

CD151

0.59	Tetraspanin

0.50	GO:0042098	T cell proliferation
0.46	GO:0016477	cell migration
0.41	GO:0007166	cell surface receptor signaling pathway

0.49	GO:0005178	integrin binding
0.36	GO:0005509	calcium ion binding

0.48	GO:0005604	basement membrane
0.40	GO:0005887	integral component of plasma membrane

tr|Q6P032|Q6P032_DANRE
MPR46
Search

M6PR

0.91	Cation-dependent Mannose-6-phosphate receptor

0.86	GO:0015761	mannose transport
0.58	GO:0033299	secretion of lysosomal enzymes
0.45	GO:0006622	protein targeting to lysosome
0.35	GO:0008333	endosome to lysosome transport
0.34	GO:0006898	receptor-mediated endocytosis
0.33	GO:0061024	membrane organization
0.33	GO:0007165	signal transduction

0.86	GO:0015578	mannose transmembrane transporter activity
0.85	GO:0005537	mannose binding
0.59	GO:1905394	retromer complex binding
0.42	GO:0019904	protein domain specific binding
0.34	GO:0004888	transmembrane signaling receptor activity

0.77	GO:0000323	lytic vacuole
0.53	GO:0030904	retromer complex
0.52	GO:0005770	late endosome
0.52	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0005802	trans-Golgi network
0.38	GO:0005774	vacuolar membrane
0.35	GO:0030665	clathrin-coated vesicle membrane
0.34	GO:0030133	transport vesicle
0.34	GO:0000139	Golgi membrane
0.33	GO:0005887	integral component of plasma membrane

sp|Q6P036|S2533_DANRE
Solute carrier family 25 member 33
Search

SLC25A33

0.97	Solute carrier family 25 (pyrimidine nucleotide carrier), member 33

0.58	GO:1990519	pyrimidine nucleotide import into mitochondrion
0.56	GO:1990314	cellular response to insulin-like growth factor stimulus
0.54	GO:0002082	regulation of oxidative phosphorylation
0.54	GO:0006390	mitochondrial transcription
0.53	GO:0031930	mitochondria-nucleus signaling pathway
0.53	GO:0051881	regulation of mitochondrial membrane potential
0.53	GO:1903426	regulation of reactive oxygen species biosynthetic process
0.53	GO:0071156	regulation of cell cycle arrest
0.52	GO:0032869	cellular response to insulin stimulus
0.52	GO:0030307	positive regulation of cell growth

0.56

GO:0015218

pyrimidine nucleotide transmembrane transporter activity

0.44	GO:0031967	organelle envelope
0.44	GO:0031090	organelle membrane
0.44	GO:0044429	mitochondrial part
0.35	GO:0012505	endomembrane system
0.35	GO:0044428	nuclear part
0.30	GO:0031224	intrinsic component of membrane

tr|Q6P038|Q6P038_DANRE
High mobility group AT-hook 2
Search

HMGA2

0.96	High mobility group protein HMGI-C

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0090402	oncogene-induced cell senescence
0.53	GO:0035986	senescence-associated heterochromatin focus assembly
0.52	GO:2000774	positive regulation of cellular senescence
0.48	GO:0031052	chromosome breakage
0.48	GO:0035978	histone H2A-S139 phosphorylation
0.48	GO:0003131	mesodermal-endodermal cell signaling
0.47	GO:0042127	regulation of cell proliferation

0.55	GO:0003677	DNA binding
0.48	GO:0035501	MH1 domain binding
0.47	GO:0051575	5'-deoxyribose-5-phosphate lyase activity
0.47	GO:0035500	MH2 domain binding
0.46	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity
0.46	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0070742	C2H2 zinc finger domain binding
0.46	GO:0042975	peroxisome proliferator activated receptor binding
0.45	GO:0046965	retinoid X receptor binding
0.45	GO:0004677	DNA-dependent protein kinase activity

0.72	GO:0000785	chromatin
0.61	GO:0005634	nucleus
0.46	GO:0071141	SMAD protein complex
0.41	GO:0032993	protein-DNA complex
0.41	GO:0070013	intracellular organelle lumen
0.36	GO:0005667	transcription factor complex
0.35	GO:0005925	focal adhesion
0.33	GO:0005829	cytosol

0.46

EC:4.2.99.18

GO:0003906

tr|Q6P041|Q6P041_DANRE
V-type proton ATPase proteolipid subunit
Search

0.61	V-type proton ATPase proteolipid subunit

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.50	GO:0007042	lysosomal lumen acidification
0.50	GO:0030177	positive regulation of Wnt signaling pathway
0.41	GO:0060036	notochord cell vacuolation
0.40	GO:0001878	response to yeast
0.40	GO:0060059	embryonic retina morphogenesis in camera-type eye
0.35	GO:0090383	phagosome acidification
0.35	GO:0033572	transferrin transport
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0008286	insulin receptor signaling pathway

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.48	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0036442	proton-exporting ATPase activity
0.44	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.34	GO:0005245	voltage-gated calcium channel activity
0.34	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.34	GO:0008448	N-acetylglucosamine-6-phosphate deacetylase activity

0.78	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.76	GO:0005774	vacuolar membrane
0.36	GO:0031982	vesicle
0.36	GO:0005925	focal adhesion
0.36	GO:0043230	extracellular organelle
0.35	GO:0005764	lysosome
0.35	GO:0012505	endomembrane system
0.35	GO:0005615	extracellular space
0.34	GO:0048786	presynaptic active zone
0.32	GO:0005886	plasma membrane

0.34

EC:3.5.1.25

GO:0008448

tr|Q6P043|Q6P043_DANRE
Fructose-bisphosphate aldolase
Search

ALDOA

0.54	Fructose-bisphosphate aldolase A

0.71	GO:0006096	glycolytic process
0.49	GO:0030388	fructose 1,6-bisphosphate metabolic process
0.46	GO:0046716	muscle cell cellular homeostasis
0.46	GO:0007339	binding of sperm to zona pellucida
0.45	GO:0006941	striated muscle contraction
0.45	GO:0006000	fructose metabolic process
0.44	GO:0060429	epithelium development
0.44	GO:0001966	thigmotaxis
0.43	GO:0030154	cell differentiation
0.42	GO:0043473	pigmentation

0.79	GO:0004332	fructose-bisphosphate aldolase activity
0.48	GO:0070061	fructose binding
0.45	GO:0008092	cytoskeletal protein binding
0.44	GO:0045296	cadherin binding
0.37	GO:0042802	identical protein binding
0.36	GO:0002020	protease binding
0.35	GO:0061609	fructose-1-phosphate aldolase activity
0.34	GO:0051117	ATPase binding
0.33	GO:0003723	RNA binding

0.47	GO:0061827	sperm head
0.44	GO:0070062	extracellular exosome
0.42	GO:0015629	actin cytoskeleton
0.42	GO:0005829	cytosol
0.40	GO:0031430	M band
0.40	GO:0031674	I band
0.37	GO:0005739	mitochondrion
0.37	GO:0035686	sperm fibrous sheath
0.36	GO:0043209	myelin sheath
0.35	GO:1904724	tertiary granule lumen

0.79

EC:4.1.2.13

GO:0004332

tr|Q6P045|Q6P045_DANRE
Thymidylate synthetase
Search

TYMS

0.46	Thymidylate synthetase

0.76	GO:0006231	dTMP biosynthetic process
0.61	GO:0032259	methylation
0.53	GO:0046683	response to organophosphorus
0.50	GO:0017148	negative regulation of translation
0.49	GO:0035999	tetrahydrofolate interconversion
0.46	GO:0060041	retina development in camera-type eye
0.43	GO:0019088	immortalization of host cell by virus
0.42	GO:0060574	intestinal epithelial cell maturation
0.42	GO:0033189	response to vitamin A
0.42	GO:0051593	response to folic acid

0.77	GO:0004799	thymidylate synthase activity
0.56	GO:1990825	sequence-specific mRNA binding
0.56	GO:0000900	translation repressor activity, nucleic acid binding
0.40	GO:0005542	folic acid binding
0.38	GO:0042803	protein homodimerization activity
0.35	GO:0048037	cofactor binding
0.34	GO:1901265	nucleoside phosphate binding

0.50	GO:0005759	mitochondrial matrix
0.44	GO:0031966	mitochondrial membrane
0.44	GO:0019866	organelle inner membrane
0.44	GO:0005634	nucleus
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.77	EC:2.1.1.45	GO:0004799
0.77	KEGG:R02101	GO:0004799

tr|Q6P0A8|Q6P0A8_DANRE
Nescient helix loop helix 2
Search

NHLH2

0.96	Nescient helix loop helix 2

0.53	GO:0006366	transcription by RNA polymerase II
0.53	GO:0045944	positive regulation of transcription by RNA polymerase II
0.50	GO:0007617	mating behavior
0.49	GO:0042698	ovulation cycle
0.36	GO:0030154	cell differentiation
0.36	GO:0007275	multicellular organism development
0.34	GO:0051091	positive regulation of DNA binding transcription factor activity

0.68	GO:0046983	protein dimerization activity
0.56	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.56	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.50	GO:0001102	RNA polymerase II activating transcription factor binding
0.48	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0000987	proximal promoter sequence-specific DNA binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|Q6P0B1|CELF2_DANRE
CUGBP Elav-like family member 2
Search

CELF2

0.90	CUGBP Elav family member 2

0.49	GO:0006376	mRNA splice site selection
0.35	GO:0000380	alternative mRNA splicing, via spliceosome
0.34	GO:0008016	regulation of heart contraction
0.34	GO:0017148	negative regulation of translation

0.58	GO:0003723	RNA binding
0.35	GO:0000900	translation repressor activity, nucleic acid binding
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.42	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm

tr|Q6P0B3|Q6P0B3_DANRE
Secretory carrier-associated membrane protein
Search

SCAMP1

0.68	Secretory carrier-associated membrane protein 1

0.65	GO:0015031	protein transport
0.48	GO:0006887	exocytosis
0.35	GO:0002283	neutrophil activation involved in immune response
0.35	GO:0002446	neutrophil mediated immunity
0.34	GO:0006892	post-Golgi vesicle-mediated transport
0.34	GO:0006897	endocytosis

0.35	GO:0005515	protein binding
0.32	GO:0003723	RNA binding

0.53	GO:0042589	zymogen granule membrane
0.52	GO:0055038	recycling endosome membrane
0.51	GO:0030672	synaptic vesicle membrane
0.49	GO:0005802	trans-Golgi network
0.36	GO:0030136	clathrin-coated vesicle
0.35	GO:0035579	specific granule membrane
0.35	GO:0043195	terminal bouton
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q6P0C5|Q6P0C5_DANRE
Brix domain containing 1
Search

RPF2

0.87	Brix domain-containing protein 1

0.84	GO:1902570	protein localization to nucleolus
0.78	GO:1901796	regulation of signal transduction by p53 class mediator
0.75	GO:0042273	ribosomal large subunit biogenesis
0.61	GO:0042255	ribosome assembly
0.56	GO:0006364	rRNA processing
0.47	GO:0090307	mitotic spindle assembly
0.40	GO:1902626	assembly of large subunit precursor of preribosome
0.37	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0051301	cell division

0.73	GO:0008097	5S rRNA binding
0.38	GO:0008312	7S RNA binding
0.37	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding

0.73

GO:0005730

nucleolus

sp|Q6P0C6|LHPL2_DANRE
Lipoma HMGIC fusion partner-like 2 protein
Search

LHFPL2

0.97	LHFPL tetraspan subfamily member 2

0.58	GO:1905516	positive regulation of fertilization
0.55	GO:0046546	development of primary male sexual characteristics
0.55	GO:0046545	development of primary female sexual characteristics
0.38	GO:0007338	single fertilization
0.35	GO:0002576	platelet degranulation

0.35	GO:0031092	platelet alpha granule membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q6P0C7|SCAM5_DANRE
Secretory carrier-associated membrane protein 5
Search

SCAMP5

0.68	Secretory carrier-associated membrane protein 5

0.65	GO:0015031	protein transport
0.56	GO:0045956	positive regulation of calcium ion-dependent exocytosis
0.54	GO:0050715	positive regulation of cytokine secretion
0.53	GO:0045806	negative regulation of endocytosis
0.50	GO:0034976	response to endoplasmic reticulum stress
0.41	GO:0006887	exocytosis

0.33	GO:0005515	protein binding
0.30	GO:0003824	catalytic activity

0.55	GO:0055038	recycling endosome membrane
0.53	GO:0032588	trans-Golgi network membrane
0.51	GO:0031201	SNARE complex
0.43	GO:0030672	synaptic vesicle membrane
0.41	GO:0005886	plasma membrane
0.40	GO:0030054	cell junction
0.30	GO:0031224	intrinsic component of membrane

tr|Q6P0C9|Q6P0C9_DANRE
Forkhead box A1
Search

FOXA1

0.95	hepatocyte nuclear factor 3-alpha

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.53	GO:0048729	tissue morphogenesis
0.52	GO:1902691	respiratory basal cell differentiation
0.52	GO:0061144	alveolar secondary septum development
0.52	GO:0060741	prostate gland stromal morphogenesis
0.52	GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development
0.51	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway

0.75	GO:0019904	protein domain specific binding
0.71	GO:0008134	transcription factor binding
0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0044212	transcription regulatory region DNA binding
0.47	GO:0003690	double-stranded DNA binding
0.34	GO:0046332	SMAD binding
0.34	GO:0019900	kinase binding

0.61	GO:0005634	nucleus
0.48	GO:0005902	microvillus
0.45	GO:0070013	intracellular organelle lumen
0.41	GO:0044446	intracellular organelle part
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0030054	cell junction
0.32	GO:0005737	cytoplasm

sp|Q6P0D0|QKIA_DANRE
Protein quaking-A
Search

QKIA

0.96	QKI, KH domain containing RNA binding

0.51	GO:0061158	3'-UTR-mediated mRNA destabilization
0.50	GO:0042759	long-chain fatty acid biosynthetic process
0.49	GO:0001570	vasculogenesis
0.49	GO:0042552	myelination
0.49	GO:0007286	spermatid development
0.48	GO:0042692	muscle cell differentiation
0.45	GO:0010628	positive regulation of gene expression

0.59

GO:0003723

RNA binding

0.41	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm

sp|Q6P0D1|ZNT6_DANRE
Zinc transporter 6
Search

SLC30A6

0.95	Zinc transporter 6-A

0.61	GO:0098655	cation transmembrane transport
0.48	GO:0061088	regulation of sequestering of zinc ion
0.47	GO:0010043	response to zinc ion
0.46	GO:0006829	zinc II ion transport
0.40	GO:0098660	inorganic ion transmembrane transport
0.37	GO:0006895	Golgi to endosome transport
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.61	GO:0008324	cation transmembrane transporter activity
0.39	GO:0015318	inorganic molecular entity transmembrane transporter activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003735	structural constituent of ribosome

0.50	GO:0005794	Golgi apparatus
0.35	GO:0005829	cytosol
0.34	GO:0005739	mitochondrion
0.34	GO:0098588	bounding membrane of organelle
0.33	GO:0031984	organelle subcompartment
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q6P0D5|WBP11_DANRE
WW domain-binding protein 11
Search

WBP11

0.91	WW domain binding protein 11

0.61	GO:0006396	RNA processing
0.58	GO:1903146	regulation of autophagy of mitochondrion
0.57	GO:1903955	positive regulation of protein targeting to mitochondrion
0.46	GO:0043666	regulation of phosphoprotein phosphatase activity
0.43	GO:0016071	mRNA metabolic process
0.37	GO:0016072	rRNA metabolic process
0.37	GO:0042254	ribosome biogenesis

0.59	GO:0050699	WW domain binding
0.47	GO:0019888	protein phosphatase regulator activity
0.35	GO:0005199	structural constituent of cell wall
0.35	GO:0003697	single-stranded DNA binding
0.34	GO:0003723	RNA binding

0.51	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.45	GO:0005681	spliceosomal complex
0.36	GO:0005730	nucleolus

sp|Q6P0D7|MPP7_DANRE
MAGUK p55 subfamily member 7
Search

MPP7

0.95	Membrane palmitoylated protein 7

0.86	GO:0071896	protein localization to adherens junction
0.84	GO:0070830	bicellular tight junction assembly
0.76	GO:0031334	positive regulation of protein complex assembly
0.40	GO:0030010	establishment of cell polarity
0.39	GO:0009967	positive regulation of signal transduction

0.79	GO:0045296	cadherin binding
0.79	GO:0032947	protein complex scaffold activity
0.74	GO:0019904	protein domain specific binding
0.72	GO:0046982	protein heterodimerization activity
0.40	GO:0035591	signaling adaptor activity

0.85	GO:0097025	MPP7-DLG1-LIN7 complex
0.80	GO:0005923	bicellular tight junction
0.68	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q6P0D9|CIAO1_DANRE
Probable cytosolic iron-sulfur protein assembly protein ciao1
Search

CIAO1

0.84	Probable cytosolic iron-sulfur protein assembly protein ciao1-A

0.73	GO:0016226	iron-sulfur cluster assembly
0.55	GO:0007059	chromosome segregation
0.35	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0008284	positive regulation of cell proliferation
0.34	GO:0002098	tRNA wobble uridine modification
0.32	GO:0007186	G-protein coupled receptor signaling pathway

0.33	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0004930	G-protein coupled receptor activity

0.84	GO:0097361	CIA complex
0.68	GO:0071817	MMXD complex
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q6P0E1|SOX2_DANRE
Transcription factor Sox-2
Search

SOX2

0.96	Sex determining region Y-box 2

0.59	GO:0021536	diencephalon development
0.58	GO:0035270	endocrine system development
0.57	GO:0048839	inner ear development
0.57	GO:0001714	endodermal cell fate specification
0.57	GO:0048732	gland development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0001654	eye development
0.56	GO:0009611	response to wounding

0.55	GO:0035198	miRNA binding
0.55	GO:0003677	DNA binding
0.51	GO:0001067	regulatory region nucleic acid binding
0.47	GO:0003700	DNA binding transcription factor activity
0.44	GO:0003682	chromatin binding
0.36	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.47	GO:0005829	cytosol
0.47	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.38	GO:0005667	transcription factor complex

tr|Q6P0E3|Q6P0E3_DANRE
Microspherule protein 1
Search

MCRS1

0.95	Microspherule protein 1

0.58	GO:1904751	positive regulation of protein localization to nucleolus
0.56	GO:0043982	histone H4-K8 acetylation
0.56	GO:0043981	histone H4-K5 acetylation
0.56	GO:0043984	histone H4-K16 acetylation
0.45	GO:0010842	retina layer formation
0.43	GO:0060271	cilium assembly
0.40	GO:0051974	negative regulation of telomerase activity
0.40	GO:1904357	negative regulation of telomere maintenance via telomere lengthening
0.35	GO:0006310	DNA recombination
0.35	GO:0006281	DNA repair

0.84	GO:0002151	G-quadruplex RNA binding
0.57	GO:0034046	poly(G) binding
0.57	GO:0043996	histone acetyltransferase activity (H4-K8 specific)
0.57	GO:0046972	histone acetyltransferase activity (H4-K16 specific)
0.57	GO:0043995	histone acetyltransferase activity (H4-K5 specific)
0.55	GO:0008266	poly(U) RNA binding
0.40	GO:0010521	telomerase inhibitor activity
0.33	GO:0005515	protein binding

0.79	GO:0071339	MLL1 complex
0.76	GO:0031011	Ino80 complex
0.50	GO:0000123	histone acetyltransferase complex
0.49	GO:0005730	nucleolus
0.39	GO:0005844	polysome
0.39	GO:0030425	dendrite
0.39	GO:0043204	perikaryon
0.38	GO:0005737	cytoplasm
0.37	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

sp|Q6P0E5|DDRGK_DANRE
DDRGK domain-containing protein 1
Search

DDRGK1

0.95	DDRGK domain-containing protein 1

0.62	GO:1990564	protein polyufmylation
0.62	GO:1905636	positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding
0.62	GO:1903721	positive regulation of I-kappaB phosphorylation
0.62	GO:1905550	regulation of protein localization to endoplasmic reticulum
0.60	GO:1905050	positive regulation of metallopeptidase activity
0.59	GO:0033146	regulation of intracellular estrogen receptor signaling pathway
0.57	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.57	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.55	GO:0030335	positive regulation of cell migration
0.55	GO:0034976	response to endoplasmic reticulum stress

0.58	GO:0001103	RNA polymerase II repressing transcription factor binding
0.55	GO:0044389	ubiquitin-like protein ligase binding
0.44	GO:0008081	phosphoric diester hydrolase activity
0.33	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0016301	kinase activity
0.32	GO:0003676	nucleic acid binding

0.53	GO:0005783	endoplasmic reticulum
0.51	GO:0005730	nucleolus
0.51	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.49	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.44

EC:3.1.4

GO:0008081

sp|Q6P0E7|AP2E_DANRE
Transcription factor AP-2-epsilon
Search

TFAP2E

0.86	Transcription factor AP-2-epsilon

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:0006366	transcription by RNA polymerase II
0.44	GO:1902680	positive regulation of RNA biosynthetic process
0.43	GO:0042127	regulation of cell proliferation
0.42	GO:0048856	anatomical structure development
0.36	GO:0030318	melanocyte differentiation
0.33	GO:0032501	multicellular organismal process
0.33	GO:0045454	cell redox homeostasis

0.61	GO:0003700	DNA binding transcription factor activity
0.48	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.46	GO:0000987	proximal promoter sequence-specific DNA binding
0.45	GO:0042803	protein homodimerization activity
0.45	GO:0046982	protein heterodimerization activity
0.33	GO:0004148	dihydrolipoyl dehydrogenase activity
0.33	GO:0050660	flavin adenine dinucleotide binding
0.32	GO:0003735	structural constituent of ribosome

0.61	GO:0005634	nucleus
0.33	GO:0022625	cytosolic large ribosomal subunit

0.33

EC:1.8.1.4

GO:0004148

sp|Q6P0E8|PLPP7_DANRE
Inactive phospholipid phosphatase 7
Search

PLPP7

0.94	Inactive phospholipid phosphatase 7

0.68	GO:0010832	negative regulation of myotube differentiation
0.39	GO:0046839	phospholipid dephosphorylation

0.45

GO:0042577

lipid phosphatase activity

0.60	GO:0005635	nuclear envelope
0.42	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q6P0F0|EMC6_DANRE
ER membrane protein complex subunit 6
Search

EMC6

0.66	ER membrane protein complex subunit 6

0.55	GO:0000045	autophagosome assembly
0.48	GO:0034975	protein folding in endoplasmic reticulum

0.35	GO:0003723	RNA binding
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0005515	protein binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.83	GO:0072546	ER membrane protein complex
0.58	GO:0097630	intrinsic component of omegasome membrane
0.50	GO:0031301	integral component of organelle membrane
0.35	GO:0019013	viral nucleocapsid
0.34	GO:0030529	intracellular ribonucleoprotein complex

tr|Q6P0F4|Q6P0F4_DANRE
RNA-binding motif protein 7
Search

RBM7

0.96	RNA-binding motif protein 7

0.53	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.48	GO:0021693	cerebellar Purkinje cell layer structural organization
0.44	GO:0007409	axonogenesis
0.42	GO:0034599	cellular response to oxidative stress
0.36	GO:0051321	meiotic cell cycle
0.34	GO:0008380	RNA splicing
0.34	GO:0006397	mRNA processing
0.34	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.32	GO:0006468	protein phosphorylation

0.59	GO:0003723	RNA binding
0.42	GO:0042803	protein homodimerization activity
0.34	GO:0000175	3'-5'-exoribonuclease activity
0.32	GO:0005524	ATP binding
0.32	GO:0004672	protein kinase activity

0.44	GO:0005634	nucleus
0.43	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.31	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.1.13

GO:0000175

tr|Q6P0F7|Q6P0F7_DANRE
Nuclear receptor coactivator 4
Search

NCOA4

0.97	Nuclear receptor coactivator 4

0.79	GO:0006622	protein targeting to lysosome
0.64	GO:0006879	cellular iron ion homeostasis
0.42	GO:0009725	response to hormone
0.39	GO:0008584	male gonad development
0.39	GO:0030150	protein import into mitochondrial matrix
0.38	GO:0030522	intracellular receptor signaling pathway
0.38	GO:0071396	cellular response to lipid
0.38	GO:0071407	cellular response to organic cyclic compound
0.37	GO:0071495	cellular response to endogenous stimulus
0.37	GO:0045893	positive regulation of transcription, DNA-templated

0.40	GO:0050681	androgen receptor binding
0.38	GO:0003713	transcription coactivator activity
0.37	GO:0004252	serine-type endopeptidase activity
0.34	GO:0004872	receptor activity

0.80	GO:0044754	autolysosome
0.53	GO:0005739	mitochondrion
0.38	GO:0031301	integral component of organelle membrane
0.36	GO:0098796	membrane protein complex
0.36	GO:0019866	organelle inner membrane
0.35	GO:0005634	nucleus
0.35	GO:0005576	extracellular region

0.37

GO:0004252

sp|Q6P0F9|INS1A_DANRE
Insulinoma-associated protein 1a
Search

0.85	Insulinoma-associated protein 1a

0.78	GO:0060221	retinal rod cell differentiation
0.77	GO:0070654	sensory epithelium regeneration
0.76	GO:0043696	dedifferentiation
0.75	GO:0042670	retinal cone cell differentiation
0.65	GO:0060290	transdifferentiation
0.64	GO:0003310	pancreatic A cell differentiation
0.64	GO:0010564	regulation of cell cycle process
0.62	GO:0003309	type B pancreatic cell differentiation
0.61	GO:0045892	negative regulation of transcription, DNA-templated
0.53	GO:0006357	regulation of transcription by RNA polymerase II

0.60	GO:0031490	chromatin DNA binding
0.59	GO:0001047	core promoter binding
0.56	GO:0043565	sequence-specific DNA binding
0.47	GO:0003700	DNA binding transcription factor activity
0.43	GO:0046872	metal ion binding

0.59	GO:0017053	transcriptional repressor complex
0.47	GO:0005634	nucleus

tr|Q6P0G2|Q6P0G2_DANRE
Zgc:77262
Search

0.78	RNA-binding protein lark

0.49	GO:0045804	negative regulation of eclosion
0.48	GO:0008062	eclosion rhythm
0.47	GO:0007303	cytoplasmic transport, nurse cell to oocyte
0.47	GO:2000767	positive regulation of cytoplasmic translation
0.46	GO:0045475	locomotor rhythm
0.45	GO:0042752	regulation of circadian rhythm
0.45	GO:0045995	regulation of embryonic development
0.44	GO:0009792	embryo development ending in birth or egg hatching
0.42	GO:0030036	actin cytoskeleton organization
0.40	GO:0008104	protein localization

0.59	GO:0003723	RNA binding
0.59	GO:0008270	zinc ion binding
0.34	GO:0005199	structural constituent of cell wall
0.33	GO:0003677	DNA binding
0.33	GO:0005102	receptor binding
0.30	GO:0003824	catalytic activity

0.41	GO:0005829	cytosol
0.39	GO:0005634	nucleus
0.33	GO:1902494	catalytic complex
0.33	GO:1990904	ribonucleoprotein complex
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|Q6P0G5|Q6P0G5_DANRE
Tfg protein
Search

TFG

0.97	LOW QUALITY PROTEIN: protein TFG

0.85	GO:0048208	COPII vesicle coating
0.37	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.35	GO:0007165	signal transduction
0.34	GO:0000187	activation of MAPK activity
0.33	GO:0048666	neuron development
0.33	GO:0018108	peptidyl-tyrosine phosphorylation

0.74	GO:0042802	identical protein binding
0.35	GO:0004871	signal transducer activity
0.33	GO:0004713	protein tyrosine kinase activity
0.33	GO:0099600	transmembrane receptor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.74	GO:0000139	Golgi membrane
0.54	GO:0070971	endoplasmic reticulum exit site
0.37	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.7.10

GO:0004713

tr|Q6P0G6|Q6P0G6_DANRE
Myosin, light chain 1, alkali; skeletal, fast
Search

0.91	Fast skeletal muscle myosin light polypeptide 3

0.36	GO:0060047	heart contraction
0.36	GO:0048738	cardiac muscle tissue development
0.35	GO:0003007	heart morphogenesis
0.35	GO:0061061	muscle structure development
0.35	GO:0002026	regulation of the force of heart contraction
0.34	GO:0006942	regulation of striated muscle contraction
0.34	GO:0006941	striated muscle contraction
0.34	GO:0003231	cardiac ventricle development
0.34	GO:0055006	cardiac cell development
0.34	GO:0061817	endoplasmic reticulum-plasma membrane tethering

0.70	GO:0005509	calcium ion binding
0.34	GO:0003785	actin monomer binding
0.34	GO:0008307	structural constituent of muscle

0.36	GO:0016459	myosin complex
0.36	GO:0044449	contractile fiber part
0.36	GO:0030016	myofibril
0.34	GO:0005903	brush border

sp|Q6P0G8|PKHJ1_DANRE
Pleckstrin homology domain-containing family J member 1
Search

PLEKHJ1

0.97	Pleckstrin like proteiny domain-containing family J member 1

0.86	GO:0001881	receptor recycling
0.85	GO:0007032	endosome organization
0.81	GO:0042147	retrograde transport, endosome to Golgi

0.83	GO:0055037	recycling endosome
0.81	GO:0005769	early endosome
0.80	GO:0005802	trans-Golgi network
0.69	GO:0005829	cytosol

tr|Q6P0H4|Q6P0H4_DANRE
Ring finger protein 13
Search

RNF13

0.93	Ring finger protein 13

0.62

GO:0051865

protein autoubiquitination

0.56	GO:0061630	ubiquitin protein ligase activity
0.48	GO:0008270	zinc ion binding

0.60	GO:0031902	late endosome membrane
0.59	GO:0005765	lysosomal membrane
0.56	GO:0005654	nucleoplasm
0.55	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q6P0H6|CSN4_DANRE
COP9 signalosome complex subunit 4
Search

COPS4

0.88	COP9 constitutive photomorphogenic homolog subunit 4

0.47	GO:0000338	protein deneddylation
0.34	GO:0043687	post-translational protein modification
0.34	GO:0000715	nucleotide-excision repair, DNA damage recognition
0.34	GO:0006283	transcription-coupled nucleotide-excision repair

0.47	GO:0019784	NEDD8-specific protease activity
0.35	GO:0005515	protein binding

0.79	GO:0008180	COP9 signalosome
0.43	GO:0008021	synaptic vesicle
0.41	GO:0005829	cytosol
0.41	GO:0030054	cell junction
0.38	GO:0016607	nuclear speck
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|Q6P0H7|CBR4_DANRE
Carbonyl reductase family member 4
Search

CBR4

0.94	Carbonyl reductase 4

0.63	GO:0006633	fatty acid biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.49	GO:0044598	doxorubicin metabolic process
0.49	GO:0044597	daunorubicin metabolic process
0.49	GO:0051290	protein heterotetramerization
0.47	GO:0051289	protein homotetramerization
0.33	GO:0046949	fatty-acyl-CoA biosynthetic process
0.32	GO:0006426	glycyl-tRNA aminoacylation

0.66	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
0.59	GO:0051287	NAD binding
0.51	GO:0047025	3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity
0.49	GO:0008753	NADPH dehydrogenase (quinone) activity
0.46	GO:0003955	NAD(P)H dehydrogenase (quinone) activity
0.45	GO:0102131	3-oxo-glutaryl-[acp] methyl ester reductase activity
0.45	GO:0102132	3-oxo-pimeloyl-[acp] methyl ester reductase activity
0.45	GO:0070402	NADPH binding
0.43	GO:0048038	quinone binding
0.32	GO:0008874	gluconate 5-dehydrogenase activity

0.45	GO:0005759	mitochondrial matrix
0.43	GO:1990204	oxidoreductase complex

0.66	EC:1.1.1.100	GO:0004316
0.49	KEGG:R07359	GO:0008753

tr|Q6P0H8|Q6P0H8_DANRE
Glycerophosphodiester phosphodiesterase 1
Search

GDE1

0.95	Glycerophosphodiester phosphodiesterase 1

0.63	GO:0006629	lipid metabolic process
0.57	GO:0070291	N-acylethanolamine metabolic process
0.42	GO:0019637	organophosphate metabolic process
0.41	GO:0006796	phosphate-containing compound metabolic process
0.35	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0044248	cellular catabolic process
0.33	GO:1901575	organic substance catabolic process

0.78	GO:0008889	glycerophosphodiester phosphodiesterase activity
0.58	GO:0047395	glycerophosphoinositol glycerophosphodiesterase activity
0.53	GO:0004622	lysophospholipase activity
0.34	GO:0046872	metal ion binding

0.38	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.78	EC:3.1.4.46	GO:0008889
0.58	KEGG:R01193	GO:0047395

tr|Q6P0I2|Q6P0I2_DANRE
Proteasome subunit alpha type
Search

0.48	Proteasome endopeptidase complex

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.68	GO:0043632	modification-dependent macromolecule catabolic process
0.37	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.37	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.37	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.37	GO:0038095	Fc-epsilon receptor signaling pathway
0.37	GO:1902036	regulation of hematopoietic stem cell differentiation
0.36	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.36	GO:0070498	interleukin-1-mediated signaling pathway
0.36	GO:0038061	NIK/NF-kappaB signaling

0.77	GO:0004298	threonine-type endopeptidase activity
0.48	GO:0042802	identical protein binding
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0003743	translation initiation factor activity
0.33	GO:0003700	DNA binding transcription factor activity

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.58	GO:0005634	nucleus
0.49	GO:1990111	spermatoproteasome complex
0.49	GO:0098794	postsynapse
0.49	GO:0005737	cytoplasm
0.38	GO:0070062	extracellular exosome
0.36	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0000428	DNA-directed RNA polymerase complex
0.34	GO:0005667	transcription factor complex

0.77

GO:0004298

sp|Q6P0I6|ZN830_DANRE
Zinc finger protein 830
Search

ZNF830

0.75	Coiled-coil domain-containing protein 16

0.58	GO:0048162	multi-layer follicle stage
0.57	GO:0060729	intestinal epithelial structure maintenance
0.56	GO:0001832	blastocyst growth
0.55	GO:0000278	mitotic cell cycle
0.54	GO:0001541	ovarian follicle development
0.54	GO:0048478	replication fork protection
0.54	GO:0000076	DNA replication checkpoint
0.53	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle
0.53	GO:0033260	nuclear DNA replication
0.52	GO:0000077	DNA damage checkpoint

0.57	GO:0008270	zinc ion binding
0.47	GO:0003676	nucleic acid binding
0.35	GO:0004648	O-phospho-L-serine:2-oxoglutarate aminotransferase activity
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0004742	dihydrolipoyllysine-residue acetyltransferase activity
0.33	GO:0005515	protein binding

0.54	GO:0016607	nuclear speck
0.40	GO:0005694	chromosome
0.33	GO:0045254	pyruvate dehydrogenase complex
0.33	GO:0005929	cilium

0.35	EC:2.6.1.52	GO:0004648
0.34	KEGG:R03876	GO:0004842

sp|Q6P0I8|EXOS6_DANRE
Exosome complex component MTR3
Search

EXOSC6

0.82	LOW QUALITY PROTEIN: exosome complex component MTR3

0.58	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing
0.57	GO:0034475	U4 snRNA 3'-end processing
0.57	GO:0045006	DNA deamination
0.57	GO:0071028	nuclear mRNA surveillance
0.57	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
0.56	GO:0031125	rRNA 3'-end processing
0.54	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response
0.54	GO:0045830	positive regulation of isotype switching
0.53	GO:0002312	B cell activation involved in immune response
0.53	GO:0016075	rRNA catabolic process

0.56	GO:0004527	exonuclease activity
0.47	GO:0004540	ribonuclease activity
0.41	GO:0003723	RNA binding
0.38	GO:0009022	tRNA nucleotidyltransferase activity
0.35	GO:0031177	phosphopantetheine binding

0.71	GO:0000178	exosome (RNase complex)
0.51	GO:0005730	nucleolus
0.44	GO:0044444	cytoplasmic part
0.39	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0005654	nucleoplasm

0.38

EC:2.7.7.56

GO:0009022

tr|Q6P0J0|Q6P0J0_DANRE
Protein phosphatase 1, regulatory (inhibitor) subunit 2
Search

PPP1R2

0.92	Protein phosphatase 1 regulatory inhibitor subunit 2

0.77	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.66	GO:0009966	regulation of signal transduction
0.40	GO:0005977	glycogen metabolic process
0.35	GO:0032091	negative regulation of protein binding
0.35	GO:0006470	protein dephosphorylation

0.78	GO:0004864	protein phosphatase inhibitor activity
0.36	GO:0005515	protein binding
0.35	GO:0031409	pigment binding
0.35	GO:0004721	phosphoprotein phosphatase activity

0.46	GO:0000164	protein phosphatase type 1 complex
0.36	GO:0098723	skeletal muscle myofibril
0.35	GO:0043197	dendritic spine
0.35	GO:0030426	growth cone
0.30	GO:0016020	membrane

0.35

EC:3.1.3.16

GO:0004721

sp|Q6P0J3|SP8_DANRE
Transcription factor Sp8
Search

0.96	Sp8 transcription factor b

0.55	GO:0030326	embryonic limb morphogenesis
0.48	GO:0009954	proximal/distal pattern formation
0.47	GO:0009953	dorsal/ventral pattern formation
0.46	GO:0035118	embryonic pectoral fin morphogenesis
0.46	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway
0.45	GO:0006357	regulation of transcription by RNA polymerase II
0.37	GO:0006351	transcription, DNA-templated
0.34	GO:0007480	imaginal disc-derived leg morphogenesis

0.51	GO:0003676	nucleic acid binding
0.46	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.36	GO:0046872	metal ion binding

0.42	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|Q6P0J9|Q6P0J9_DANRE
Phosphatidylinositol glycan anchor biosynthesis, class F
Search

PIGF

0.96	Phosphatidylinositol glycan anchor biosynthesis class F

0.78	GO:0006506	GPI anchor biosynthetic process
0.33	GO:0010466	negative regulation of peptidase activity
0.33	GO:0006606	protein import into nucleus
0.32	GO:0030447	filamentous growth
0.32	GO:0016310	phosphorylation
0.31	GO:1903506	regulation of nucleic acid-templated transcription
0.31	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.31	GO:0010468	regulation of gene expression

0.39	GO:0004307	ethanolaminephosphotransferase activity
0.33	GO:0030414	peptidase inhibitor activity
0.33	GO:0061608	nuclear import signal receptor activity
0.32	GO:0051377	mannose-ethanolamine phosphotransferase activity
0.32	GO:0008565	protein transporter activity
0.32	GO:0016301	kinase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.31	GO:0003700	DNA binding transcription factor activity
0.31	GO:0003677	DNA binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.32	GO:0005576	extracellular region
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.39

EC:2.7.8.1

GO:0004307

tr|Q6P0K1|Q6P0K1_DANRE
Connector enhancer of kinase suppressor of Ras 1
Search

CNKSR1

0.82	Connector enhancer of kinase suppressor of Ras 1

0.56	GO:0009966	regulation of signal transduction
0.51	GO:0007266	Rho protein signal transduction
0.51	GO:0016310	phosphorylation
0.34	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

0.53	GO:0016301	kinase activity
0.49	GO:0030674	protein binding, bridging
0.33	GO:0042802	identical protein binding

0.48	GO:0005938	cell cortex
0.41	GO:0014069	postsynaptic density
0.34	GO:0043025	neuronal cell body
0.34	GO:0070062	extracellular exosome
0.34	GO:0005911	cell-cell junction
0.34	GO:0045211	postsynaptic membrane
0.34	GO:0043005	neuron projection
0.30	GO:0031224	intrinsic component of membrane

tr|Q6P0R4|Q6P0R4_DANRE
Cytidine deaminase
Search

CDA

0.48	Cytidine deaminase

0.78	GO:0009972	cytidine deamination
0.48	GO:0045980	negative regulation of nucleotide metabolic process
0.47	GO:0051289	protein homotetramerization
0.47	GO:0030308	negative regulation of cell growth
0.36	GO:0006217	deoxycytidine catabolic process
0.35	GO:0071217	cellular response to external biotic stimulus
0.35	GO:0046898	response to cycloheximide
0.35	GO:0008655	pyrimidine-containing compound salvage

0.79	GO:0004126	cytidine deaminase activity
0.62	GO:0008270	zinc ion binding
0.44	GO:0042802	identical protein binding
0.42	GO:0046983	protein dimerization activity
0.41	GO:0001882	nucleoside binding

0.40	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.79

EC:3.5.4.5

GO:0004126

sp|Q6P0R8|SHOT1_DANRE
Shootin-1
Search

SHTN1

0.86	Shootin-1 isoform a

0.82	GO:0061163	endoplasmic reticulum polarization
0.81	GO:2001224	positive regulation of neuron migration
0.71	GO:0048812	neuron projection morphogenesis
0.69	GO:2000114	regulation of establishment of cell polarity
0.55	GO:0061573	actin filament bundle retrograde transport
0.54	GO:0032488	Cdc42 protein signal transduction
0.53	GO:0060327	cytoplasmic actin-based contraction involved in cell motility
0.53	GO:0006930	substrate-dependent cell migration, cell extension
0.51	GO:0045773	positive regulation of axon extension
0.51	GO:0038007	netrin-activated signaling pathway

0.74	GO:0019894	kinesin binding
0.72	GO:0045296	cadherin binding
0.57	GO:0003779	actin binding
0.47	GO:0032403	protein complex binding
0.39	GO:0008502	melatonin receptor activity
0.34	GO:0003777	microtubule motor activity
0.34	GO:0008017	microtubule binding
0.34	GO:0043565	sequence-specific DNA binding
0.33	GO:0017022	myosin binding
0.33	GO:0017048	Rho GTPase binding

0.79	GO:0044295	axonal growth cone
0.77	GO:0043204	perikaryon
0.72	GO:0031252	cell leading edge
0.71	GO:0048471	perinuclear region of cytoplasm
0.69	GO:0005875	microtubule associated complex
0.64	GO:0005874	microtubule
0.50	GO:0030175	filopodium
0.36	GO:0005829	cytosol
0.34	GO:0016459	myosin complex
0.33	GO:0005634	nucleus

sp|Q6P0S3|TM45B_DANRE
Transmembrane protein 45B
Search

TMEM45B

0.89	Transmembrane protein 45B isoform B

0.30

GO:0044425

membrane part

tr|Q6P0S4|Q6P0S4_DANRE
V-fos FBJ murine osteosarcoma viral oncogene homolog
Search

FOS

0.95	Proto-oncogene protein c-fos

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.56	GO:0035994	response to muscle stretch
0.56	GO:0045672	positive regulation of osteoclast differentiation
0.55	GO:0071277	cellular response to calcium ion
0.55	GO:0035914	skeletal muscle cell differentiation
0.55	GO:0071276	cellular response to cadmium ion
0.55	GO:0060395	SMAD protein signal transduction
0.53	GO:0007179	transforming growth factor beta receptor signaling pathway
0.50	GO:0006366	transcription by RNA polymerase II
0.50	GO:0034614	cellular response to reactive oxygen species

0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0070412	R-SMAD binding
0.55	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.54	GO:0001102	RNA polymerase II activating transcription factor binding
0.54	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.52	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0003682	chromatin binding
0.50	GO:0046982	protein heterodimerization activity
0.32	GO:0005198	structural molecule activity

0.71	GO:0005667	transcription factor complex
0.48	GO:0032993	protein-DNA complex
0.48	GO:0005654	nucleoplasm
0.40	GO:0005783	endoplasmic reticulum
0.40	GO:0005829	cytosol
0.37	GO:0043005	neuron projection
0.34	GO:0042025	host cell nucleus
0.33	GO:0019028	viral capsid
0.30	GO:0016020	membrane

tr|Q6P0S5|Q6P0S5_DANRE
Alcohol dehydrogenase 8a
Search

0.38	Alcohol dehydrogenase Class VI

0.58	GO:0006067	ethanol metabolic process
0.53	GO:0055114	oxidation-reduction process
0.43	GO:0001523	retinoid metabolic process
0.42	GO:0051775	response to redox state
0.41	GO:0018119	peptidyl-cysteine S-nitrosylation
0.41	GO:0003016	respiratory system process
0.40	GO:0045777	positive regulation of blood pressure
0.40	GO:0046292	formaldehyde metabolic process
0.40	GO:1901700	response to oxygen-containing compound
0.40	GO:0009617	response to bacterium

0.62	GO:0008270	zinc ion binding
0.56	GO:0051903	S-(hydroxymethyl)glutathione dehydrogenase activity
0.48	GO:0004022	alcohol dehydrogenase (NAD) activity
0.44	GO:0018467	formaldehyde dehydrogenase activity
0.43	GO:0005504	fatty acid binding
0.39	GO:0042803	protein homodimerization activity
0.39	GO:0035276	ethanol binding
0.37	GO:0004031	aldehyde oxidase activity
0.37	GO:0019841	retinol binding
0.37	GO:0004745	retinol dehydrogenase activity

0.37	GO:0005829	cytosol
0.36	GO:0005739	mitochondrion
0.36	GO:0005576	extracellular region
0.35	GO:0031982	vesicle
0.34	GO:0005886	plasma membrane
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.56	EC:1.1.1.284	GO:0051903
0.56	KEGG:R06983 KEGG:R07140	GO:0051903

tr|Q6P0T0|Q6P0T0_DANRE
NADH dehydrogenase (Ubiquinone) Fe-S protein 8, (NADH-coenzyme Q reductase)
Search

NDUFS8

0.92	NADH dehydrogenase iron-sulfur protein 8, mitochondrial

0.53	GO:0055114	oxidation-reduction process
0.51	GO:0032981	mitochondrial respiratory chain complex I assembly
0.46	GO:0006979	response to oxidative stress
0.36	GO:0015991	ATP hydrolysis coupled proton transport
0.33	GO:0006119	oxidative phosphorylation

0.67	GO:0051539	4 iron, 4 sulfur cluster binding
0.67	GO:0016651	oxidoreductase activity, acting on NAD(P)H
0.35	GO:0046872	metal ion binding
0.35	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.50	GO:0005747	mitochondrial respiratory chain complex I
0.37	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.34	GO:0044437	vacuolar part
0.34	GO:0005759	mitochondrial matrix
0.30	GO:0016021	integral component of membrane

0.67

EC:1.6

GO:0016651

tr|Q6P0T1|Q6P0T1_DANRE
Zgc:77838
Search

0.71	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.70	GO:0000209	protein polyubiquitination
0.67	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

0.66	GO:0061630	ubiquitin protein ligase activity
0.38	GO:0005515	protein binding
0.37	GO:0016874	ligase activity

0.39	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0016874

sp|Q6P0T2|TAF8_DANRE
Transcription initiation factor TFIID subunit 8
Search

TAF8

0.87	Transcription initiation factor TFIID subunit 8

0.60	GO:0006413	translational initiation
0.55	GO:0051457	maintenance of protein location in nucleus
0.54	GO:0045598	regulation of fat cell differentiation
0.53	GO:0001833	inner cell mass cell proliferation
0.49	GO:0045893	positive regulation of transcription, DNA-templated
0.39	GO:0030154	cell differentiation
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:0006030	chitin metabolic process
0.35	GO:0016073	snRNA metabolic process
0.35	GO:0005975	carbohydrate metabolic process

0.71	GO:0046982	protein heterodimerization activity
0.60	GO:0003743	translation initiation factor activity
0.37	GO:0008061	chitin binding
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.75	GO:0005669	transcription factor TFIID complex
0.51	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0004553

tr|Q6P0T8|Q6P0T8_DANRE
Myozenin 1a
Search

MYOZ1

0.95	Calsarcin 2

0.68

GO:0030239

myofibril assembly

0.87	GO:0051373	FATZ binding
0.73	GO:0031433	telethonin binding
0.60	GO:0003779	actin binding

0.73	GO:0015629	actin cytoskeleton
0.67	GO:0030018	Z disc
0.48	GO:0031143	pseudopodium
0.40	GO:0005634	nucleus

sp|Q6P0U0|NAGA_DANRE
N-acetylglucosamine-6-phosphate deacetylase
Search

AMDHD2

0.55	N-acetylglucosamine-6-phosphate deacetylase

0.76	GO:0006044	N-acetylglucosamine metabolic process
0.55	GO:0005975	carbohydrate metabolic process
0.46	GO:1901072	glucosamine-containing compound catabolic process
0.40	GO:0019262	N-acetylneuraminate catabolic process
0.37	GO:0015991	ATP hydrolysis coupled proton transport
0.34	GO:0006048	UDP-N-acetylglucosamine biosynthetic process

0.78	GO:0008448	N-acetylglucosamine-6-phosphate deacetylase activity
0.52	GO:0046872	metal ion binding
0.35	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0005515	protein binding

0.40	GO:0005634	nucleus
0.37	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.78

EC:3.5.1.25

GO:0008448

sp|Q6P0U3|RSLBB_DANRE
Ras-like protein family member 11B
Search

RASL11B

0.97	RAS like family 11 member B

0.61	GO:0007165	signal transduction
0.55	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.47	GO:0048382	mesendoderm development
0.39	GO:0045943	positive regulation of transcription by RNA polymerase I
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.55	GO:0005160	transforming growth factor beta receptor binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003735	structural constituent of ribosome

0.37	GO:0005730	nucleolus
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

tr|Q6P0U4|Q6P0U4_DANRE
Claudin a
Search

0.65

Claudin a

0.42	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.41	GO:0048856	anatomical structure development
0.41	GO:0045216	cell-cell junction organization
0.40	GO:0051291	protein heterooligomerization
0.40	GO:0033561	regulation of water loss via skin
0.40	GO:0002028	regulation of sodium ion transport
0.39	GO:0034329	cell junction assembly
0.39	GO:0001666	response to hypoxia
0.39	GO:0070293	renal absorption
0.38	GO:0051260	protein homooligomerization

0.62	GO:0005198	structural molecule activity
0.38	GO:0042802	identical protein binding
0.37	GO:0005254	chloride channel activity
0.36	GO:0104005	hijacked molecular function

0.81	GO:0005923	bicellular tight junction
0.56	GO:0005886	plasma membrane
0.35	GO:1990794	basolateral part of cell
0.34	GO:0045177	apical part of cell
0.34	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|Q6P0U6|Q6P0U6_DANRE
DnaJ (Hsp40) homolog, subfamily C, member 3
Search

DNAJC3

0.91	Interferon-induced, double-stranded RNA-activated protein kinase inhibitor (Fragment)

0.85	GO:0036494	positive regulation of translation initiation in response to endoplasmic reticulum stress
0.84	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
0.76	GO:0070417	cellular response to cold
0.73	GO:0006469	negative regulation of protein kinase activity
0.70	GO:0043066	negative regulation of apoptotic process
0.64	GO:0051603	proteolysis involved in cellular protein catabolic process
0.49	GO:0006986	response to unfolded protein
0.42	GO:0016310	phosphorylation
0.42	GO:0035967	cellular response to topologically incorrect protein
0.40	GO:0043312	neutrophil degranulation

0.78	GO:0051787	misfolded protein binding
0.75	GO:0004860	protein kinase inhibitor activity
0.71	GO:0019901	protein kinase binding
0.69	GO:0051087	chaperone binding
0.43	GO:0016301	kinase activity

0.77	GO:0031205	endoplasmic reticulum Sec complex
0.74	GO:0005788	endoplasmic reticulum lumen
0.63	GO:0005829	cytosol
0.51	GO:0005790	smooth endoplasmic reticulum
0.42	GO:0070062	extracellular exosome
0.40	GO:0035578	azurophil granule lumen
0.30	GO:0016021	integral component of membrane

sp|Q6P0U9|NUPL2_DANRE
Nucleoporin-like protein 2
Search

NUPL2

0.89	Nucleoporin like 2

0.61	GO:0006611	protein export from nucleus
0.50	GO:0051028	mRNA transport
0.43	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.43	GO:0000056	ribosomal small subunit export from nucleus
0.42	GO:0000055	ribosomal large subunit export from nucleus
0.42	GO:0006405	RNA export from nucleus
0.39	GO:0007077	mitotic nuclear envelope disassembly
0.38	GO:1900034	regulation of cellular response to heat
0.38	GO:0071431	tRNA-containing ribonucleoprotein complex export from nucleus
0.38	GO:0006110	regulation of glycolytic process

0.62	GO:0005049	nuclear export signal receptor activity
0.50	GO:0046872	metal ion binding
0.42	GO:0005487	structural constituent of nuclear pore
0.38	GO:0004003	ATP-dependent DNA helicase activity
0.36	GO:0003676	nucleic acid binding
0.36	GO:0015288	porin activity
0.36	GO:0043168	anion binding
0.36	GO:0017076	purine nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0008144	drug binding

0.58	GO:0005635	nuclear envelope
0.48	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.44	GO:0043234	protein complex
0.43	GO:0005882	intermediate filament
0.42	GO:0031090	organelle membrane
0.40	GO:0001750	photoreceptor outer segment
0.35	GO:0044216	other organism cell
0.35	GO:0018995	host
0.34	GO:0019867	outer membrane

0.32

GO:0016740

tr|Q6P0V0|Q6P0V0_DANRE
Heterogeneous nuclear ribonucleoprotein H1
Search

0.85	Heterogeneous nuclear ribonucleoprotein H

0.45	GO:0043484	regulation of RNA splicing
0.36	GO:0008380	RNA splicing
0.36	GO:0006397	mRNA processing
0.35	GO:0071495	cellular response to endogenous stimulus
0.34	GO:0071310	cellular response to organic substance
0.34	GO:0071774	response to fibroblast growth factor
0.34	GO:1901652	response to peptide
0.34	GO:1901699	cellular response to nitrogen compound
0.34	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.33	GO:1901701	cellular response to oxygen-containing compound

0.59	GO:0003723	RNA binding
0.35	GO:0005515	protein binding

0.60	GO:0019013	viral nucleocapsid
0.55	GO:0030529	intracellular ribonucleoprotein complex
0.45	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.39	GO:1902494	catalytic complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q6P0V6|RL8_DANRE
60S ribosomal protein L8
Search

RPL8

0.80	Ribosomal protein L8

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.37	GO:1990090	cellular response to nerve growth factor stimulus
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis

0.64	GO:0003735	structural constituent of ribosome
0.54	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.63	GO:0015934	large ribosomal subunit
0.52	GO:0022626	cytosolic ribosome
0.51	GO:0042788	polysomal ribosome
0.36	GO:0005925	focal adhesion
0.30	GO:0016020	membrane

0.32

GO:0016787

tr|Q6P0V8|Q6P0V8_DANRE
Annexin
Search

ANXA5

0.62

Annexin

0.75	GO:0050819	negative regulation of coagulation
0.45	GO:2000145	regulation of cell motility
0.43	GO:0010033	response to organic substance
0.38	GO:0007596	blood coagulation
0.38	GO:0051592	response to calcium ion
0.37	GO:0050709	negative regulation of protein secretion
0.36	GO:0006909	phagocytosis
0.36	GO:0032717	negative regulation of interleukin-8 production
0.36	GO:2000482	regulation of interleukin-8 secretion
0.36	GO:0032088	negative regulation of NF-kappaB transcription factor activity

0.81	GO:0005544	calcium-dependent phospholipid binding
0.69	GO:0005509	calcium ion binding
0.39	GO:0048306	calcium-dependent protein binding
0.39	GO:0008429	phosphatidylethanolamine binding
0.37	GO:0044548	S100 protein binding
0.36	GO:0051059	NF-kappaB binding
0.35	GO:0042802	identical protein binding
0.35	GO:0035374	chondroitin sulfate binding
0.34	GO:0017046	peptide hormone binding
0.34	GO:0030971	receptor tyrosine kinase binding

0.50	GO:0072563	endothelial microparticle
0.46	GO:0009897	external side of plasma membrane
0.39	GO:0031982	vesicle
0.37	GO:0005622	intracellular
0.37	GO:0043230	extracellular organelle
0.37	GO:0012505	endomembrane system
0.36	GO:0030496	midbody
0.35	GO:0044422	organelle part
0.35	GO:0031975	envelope
0.34	GO:0031974	membrane-enclosed lumen

0.34

EC:3.6.3.8

GO:0005388

tr|Q6P0X9|Q6P0X9_DANRE
Origin recognition complex, subunit 5
Search

ORC5

0.91	origin recognition complex subunit 5

0.66	GO:0006260	DNA replication
0.35	GO:0000082	G1/S transition of mitotic cell cycle
0.32	GO:0019441	tryptophan catabolic process to kynurenine

0.48	GO:0003688	DNA replication origin binding
0.34	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0004061	arylformamidase activity

0.82	GO:0000808	origin recognition complex
0.61	GO:0005634	nucleus
0.49	GO:0031974	membrane-enclosed lumen
0.48	GO:0005829	cytosol
0.37	GO:0000781	chromosome, telomeric region
0.30	GO:0031224	intrinsic component of membrane

0.32

EC:3.5.1.9

GO:0004061

tr|Q6P0Z0|Q6P0Z0_DANRE
Lamin L3
Search

LMNA

0.86	Nuclear lamin LIII

0.50	GO:0035105	sterol regulatory element binding protein import into nucleus
0.50	GO:1903243	negative regulation of cardiac muscle hypertrophy in response to stress
0.50	GO:0090342	regulation of cell aging
0.48	GO:0072201	negative regulation of mesenchymal cell proliferation
0.48	GO:0055015	ventricular cardiac muscle cell development
0.48	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.47	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity
0.47	GO:0071456	cellular response to hypoxia
0.47	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.46	GO:0006998	nuclear envelope organization

0.62	GO:0005198	structural molecule activity
0.35	GO:0042802	identical protein binding
0.35	GO:0008157	protein phosphatase 1 binding
0.32	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.79	GO:0005882	intermediate filament
0.53	GO:0005652	nuclear lamina
0.50	GO:0031965	nuclear membrane
0.43	GO:0005654	nucleoplasm
0.36	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0031012	extracellular matrix
0.35	GO:0019866	organelle inner membrane
0.34	GO:0016363	nuclear matrix
0.33	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

tr|Q6P0Z3|Q6P0Z3_DANRE
WW domain-binding protein 1
Search

0.72	WW domain-binding protein 1

0.33	GO:0051301	cell division
0.33	GO:0007049	cell cycle

0.39	GO:0050699	WW domain binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0001883	purine nucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0032549	ribonucleoside binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0031011	Ino80 complex
0.30	GO:0044425	membrane part

tr|Q6P0Z4|Q6P0Z4_DANRE
SRY (sex determining region Y)-box 4a
Search

0.85	SRY-box containing gene 4a

0.44	GO:0061386	closure of optic fissure
0.43	GO:0045879	negative regulation of smoothened signaling pathway
0.43	GO:0031018	endocrine pancreas development
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression

0.55	GO:0003677	DNA binding
0.38	GO:0003700	DNA binding transcription factor activity

0.61

GO:0005634

nucleus

tr|Q6P0Z8|Q6P0Z8_DANRE
Zgc:77375
Search

0.83	Haloacid dehalogenase like hydrolase domain containing 5

0.67	GO:0046474	glycerophospholipid biosynthetic process
0.44	GO:0000350	generation of catalytic spliceosome for second transesterification step

0.60

GO:0005739

mitochondrion

tr|Q6P101|Q6P101_DANRE
Slc35b2 protein
Search

SLC35B2

0.95	Adenosine 3'-phospho 5'-phosphosulfate transporter 1

0.57	GO:0046963	3'-phosphoadenosine 5'-phosphosulfate transport
0.55	GO:1901679	nucleotide transmembrane transport
0.55	GO:0072530	purine-containing compound transmembrane transport
0.47	GO:0098656	anion transmembrane transport
0.46	GO:0031290	retinal ganglion cell axon guidance
0.45	GO:0042476	odontogenesis
0.45	GO:0001649	osteoblast differentiation
0.45	GO:0030166	proteoglycan biosynthetic process
0.45	GO:0051216	cartilage development
0.44	GO:0030198	extracellular matrix organization

0.57	GO:0046964	3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity
0.34	GO:0004871	signal transducer activity

0.49	GO:0005794	Golgi apparatus
0.45	GO:0030176	integral component of endoplasmic reticulum membrane
0.45	GO:0031301	integral component of organelle membrane
0.43	GO:0098588	bounding membrane of organelle

tr|Q6P102|Q6P102_DANRE
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like
Search

0.88	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like

0.51	GO:0090168	Golgi reassembly
0.50	GO:0051683	establishment of Golgi localization
0.49	GO:0006605	protein targeting
0.48	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway
0.48	GO:0051220	cytoplasmic sequestering of protein
0.47	GO:0035308	negative regulation of protein dephosphorylation
0.45	GO:0010941	regulation of cell death
0.44	GO:0043085	positive regulation of catalytic activity
0.39	GO:0051291	protein heterooligomerization
0.38	GO:0055114	oxidation-reduction process

0.77	GO:0019904	protein domain specific binding
0.53	GO:0045296	cadherin binding
0.50	GO:0042802	identical protein binding
0.49	GO:0050815	phosphoserine residue binding
0.49	GO:0019899	enzyme binding
0.48	GO:0044325	ion channel binding
0.44	GO:0008134	transcription factor binding
0.43	GO:0004497	monooxygenase activity
0.39	GO:0008022	protein C-terminus binding
0.38	GO:0003714	transcription corepressor activity

0.46	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0042470	melanosome
0.43	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.41	GO:0005739	mitochondrion
0.38	GO:0017053	transcriptional repressor complex
0.38	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome
0.37	GO:0030659	cytoplasmic vesicle membrane
0.36	GO:0072562	blood microparticle

sp|Q6P104|QKIB_DANRE
Protein quaking-B
Search

QKI

0.95	Quaking homolog, KH domain RNA binding

0.46	GO:0061158	3'-UTR-mediated mRNA destabilization
0.45	GO:0030154	cell differentiation
0.45	GO:0042759	long-chain fatty acid biosynthetic process
0.45	GO:0007275	multicellular organism development
0.45	GO:0051028	mRNA transport
0.44	GO:0008380	RNA splicing
0.44	GO:0007283	spermatogenesis
0.43	GO:0061061	muscle structure development
0.43	GO:0022412	cellular process involved in reproduction in multicellular organism
0.43	GO:0006397	mRNA processing

0.59	GO:0003723	RNA binding
0.46	GO:0017124	SH3 domain binding

0.42	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm

tr|Q6P109|Q6P109_DANRE
Casein kinase 1 epsilon
Search

CSNK1D

0.70	Casein kinase I

0.62	GO:0006468	protein phosphorylation
0.52	GO:2000052	positive regulation of non-canonical Wnt signaling pathway
0.51	GO:0018209	peptidyl-serine modification
0.51	GO:0032922	circadian regulation of gene expression
0.50	GO:0071539	protein localization to centrosome
0.50	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.50	GO:0061512	protein localization to cilium
0.50	GO:1905515	non-motile cilium assembly
0.50	GO:0042752	regulation of circadian rhythm
0.50	GO:0034067	protein localization to Golgi apparatus

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0045296	cadherin binding
0.37	GO:0042277	peptide binding

0.49	GO:0005876	spindle microtubule
0.48	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005813	centrosome
0.45	GO:0005794	Golgi apparatus
0.44	GO:0005634	nucleus
0.39	GO:0005886	plasma membrane
0.37	GO:0043005	neuron projection
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0005829	cytosol
0.34	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment

tr|Q6P111|Q6P111_DANRE
LSM14 homolog A (SCD6, S. cerevisiae)
Search

LSM14A

0.90	LSM14A mRNA processing body assembly factor a

0.74	GO:0033962	cytoplasmic mRNA processing body assembly
0.72	GO:0039529	RIG-I signaling pathway
0.70	GO:0060340	positive regulation of type I interferon-mediated signaling pathway
0.47	GO:0006417	regulation of translation
0.46	GO:0007275	multicellular organism development
0.42	GO:0034249	negative regulation of cellular amide metabolic process
0.41	GO:0032269	negative regulation of cellular protein metabolic process
0.41	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.40	GO:0010629	negative regulation of gene expression
0.37	GO:0098655	cation transmembrane transport

0.62	GO:0003727	single-stranded RNA binding
0.60	GO:0003725	double-stranded RNA binding
0.57	GO:0003690	double-stranded DNA binding
0.46	GO:0017151	DEAD/H-box RNA helicase binding
0.37	GO:0008324	cation transmembrane transporter activity

0.71	GO:0000932	P-body
0.71	GO:0010494	cytoplasmic stress granule
0.58	GO:0005829	cytosol
0.35	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q6P112|RGL1_DANRE
Ral guanine nucleotide dissociation stimulator-like 1
Search

RGL1

0.94	Ral guanine nucleotide dissociation stimulator like 1

0.77	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.34	GO:0019216	regulation of lipid metabolic process

0.86	GO:0008321	Ral guanyl-nucleotide exchange factor activity
0.33	GO:0003723	RNA binding

0.45

GO:0005622

intracellular

tr|Q6P115|Q6P115_DANRE
Nuclear receptor subfamily 2, group F, member 6b
Search

NR2F6

0.88	Estrogen receptor

0.79	GO:0030522	intracellular receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0050965	detection of temperature stimulus involved in sensory perception of pain
0.51	GO:0043153	entrainment of circadian clock by photoperiod
0.47	GO:0048666	neuron development
0.45	GO:0051253	negative regulation of RNA metabolic process

0.82	GO:0004879	nuclear receptor activity
0.79	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.50	GO:0035326	enhancer binding
0.49	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|Q6P116|RCOR2_DANRE
REST corepressor 2
Search

RCOR2

0.91	REST corepressor 2

0.47	GO:0045892	negative regulation of transcription, DNA-templated
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0006351	transcription, DNA-templated

0.54	GO:0003677	DNA binding
0.51	GO:0003714	transcription corepressor activity
0.45	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0019899	enzyme binding
0.44	GO:0008134	transcription factor binding
0.43	GO:0003700	DNA binding transcription factor activity

0.60	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.46	GO:0017053	transcriptional repressor complex
0.34	GO:0000785	chromatin

tr|Q6P117|Q6P117_DANRE
Nuclear receptor subfamily 2, group F, member 6a
Search

NR2F6

0.87	Estrogen receptor

0.79	GO:0030522	intracellular receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0050965	detection of temperature stimulus involved in sensory perception of pain
0.51	GO:0043153	entrainment of circadian clock by photoperiod
0.46	GO:0048666	neuron development
0.44	GO:0051253	negative regulation of RNA metabolic process

0.82	GO:0004879	nuclear receptor activity
0.79	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.49	GO:0035326	enhancer binding
0.48	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

tr|Q6P119|Q6P119_DANRE
Zgc:77225
Search

NDUFB3

0.42	Mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3

0.61	GO:0022900	electron transport chain
0.55	GO:0032981	mitochondrial respiratory chain complex I assembly
0.33	GO:0006119	oxidative phosphorylation
0.33	GO:0045333	cellular respiration

0.34

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.82	GO:0005747	mitochondrial respiratory chain complex I
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.34

GO:0008137

sp|Q6P121|HYCCI_DANRE
Hyccin
Search

FAM126A

0.96	Hyccin isoform B

0.76	GO:0042552	myelination
0.75	GO:0072659	protein localization to plasma membrane
0.68	GO:0046854	phosphatidylinositol phosphorylation
0.35	GO:0007165	signal transduction

0.37	GO:0005515	protein binding
0.36	GO:0004871	signal transducer activity

0.69	GO:0043005	neuron projection
0.63	GO:0005829	cytosol
0.52	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q6P124|Q6P124_DANRE
GTPase activating protein (SH3 domain) binding protein 1
Search

G3BP1

0.82	Ras GTPase-activating protein-binding protein 1

0.59	GO:0034063	stress granule assembly
0.43	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.37	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.36	GO:0007265	Ras protein signal transduction
0.35	GO:0032392	DNA geometric change

0.59	GO:0003723	RNA binding
0.38	GO:0004386	helicase activity
0.38	GO:0004519	endonuclease activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0003677	DNA binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0008186	RNA-dependent ATPase activity
0.35	GO:0005515	protein binding
0.35	GO:0008094	DNA-dependent ATPase activity

0.42	GO:0010494	cytoplasmic stress granule
0.40	GO:0005829	cytosol
0.37	GO:0005634	nucleus
0.36	GO:0005925	focal adhesion
0.36	GO:0005886	plasma membrane

tr|Q6P129|Q6P129_DANRE
RAB18A, member RAS oncogene family
Search

RAB18

0.94	RAB18, member RAS oncogene family

0.62	GO:0034389	lipid particle organization
0.59	GO:0071786	endoplasmic reticulum tubular network organization
0.47	GO:0051170	nuclear import
0.40	GO:0001654	eye development
0.40	GO:0043009	chordate embryonic development
0.37	GO:0007420	brain development

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.57	GO:0071782	endoplasmic reticulum tubular network
0.46	GO:0005794	Golgi apparatus

tr|Q6P131|Q6P131_DANRE
Thioredoxin 2
Search

TXN2

0.38	Mitochondrial thioredoxin

0.75	GO:0006662	glycerol ether metabolic process
0.69	GO:0045454	cell redox homeostasis
0.52	GO:0055114	oxidation-reduction process
0.38	GO:0048678	response to axon injury
0.37	GO:0009749	response to glucose
0.37	GO:0001666	response to hypoxia
0.36	GO:0031669	cellular response to nutrient levels
0.36	GO:0014070	response to organic cyclic compound
0.36	GO:0009725	response to hormone
0.35	GO:0006979	response to oxidative stress

0.71	GO:0015035	protein disulfide oxidoreductase activity
0.36	GO:0033743	peptide-methionine (R)-S-oxide reductase activity
0.36	GO:0008113	peptide-methionine (S)-S-oxide reductase activity
0.36	GO:0032403	protein complex binding
0.33	GO:0098808	mRNA cap binding
0.32	GO:0003743	translation initiation factor activity

0.45	GO:0005730	nucleolus
0.41	GO:0005739	mitochondrion
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.33	GO:0016282	eukaryotic 43S preinitiation complex
0.33	GO:0033290	eukaryotic 48S preinitiation complex
0.32	GO:0005852	eukaryotic translation initiation factor 3 complex

0.36	EC:1.8.4 EC:1.8.4.12	GO:0033743
0.36	KEGG:R07607	GO:0033743

sp|Q6P132|TXB1B_DANRE
Tax1-binding protein 1 homolog B
Search

TAX1BP1

0.92	Tax1 (human T-cell leukemia virus type I) binding protein 1b

0.80	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.54	GO:0006915	apoptotic process
0.43	GO:0043066	negative regulation of apoptotic process
0.39	GO:0010976	positive regulation of neuron projection development
0.35	GO:0032480	negative regulation of type I interferon production
0.35	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway

0.74	GO:0019900	kinase binding
0.42	GO:0046872	metal ion binding
0.40	GO:0043130	ubiquitin binding

0.41	GO:0005615	extracellular space
0.40	GO:1903561	extracellular vesicle
0.37	GO:0005783	endoplasmic reticulum
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q6P135|TMUB1_DANRE
Transmembrane and ubiquitin-like domain-containing protein 1
Search

TMUB2

0.95	Transmembrane and ubiquitin domain-containing protein 1

0.48	GO:0030433	ubiquitin-dependent ERAD pathway
0.32	GO:0090501	RNA phosphodiester bond hydrolysis
0.32	GO:0008033	tRNA processing

0.34	GO:0005515	protein binding
0.32	GO:0004540	ribonuclease activity

0.45	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.37	GO:0055037	recycling endosome
0.37	GO:0045211	postsynaptic membrane
0.36	GO:0005815	microtubule organizing center
0.36	GO:0030054	cell junction
0.36	GO:0005730	nucleolus
0.30	GO:0016021	integral component of membrane

tr|Q6P1S3|Q6P1S3_DANRE
X-prolyl aminopeptidase (Aminopeptidase P) 1, soluble
Search

XPNPEP1

0.89	X-prolyl aminopeptidase

0.59	GO:0006508	proteolysis
0.57	GO:0010815	bradykinin catabolic process

0.75	GO:0070006	metalloaminopeptidase activity
0.53	GO:0046872	metal ion binding
0.49	GO:0042803	protein homodimerization activity

0.47	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome

sp|Q6P268|PDCL3_DANRE
Phosducin-like protein 3
Search

PDCL3

0.93	Phosducin like 3

0.80	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.77	GO:0001938	positive regulation of endothelial cell proliferation
0.75	GO:0045766	positive regulation of angiogenesis
0.74	GO:0050730	regulation of peptidyl-tyrosine phosphorylation
0.62	GO:0006457	protein folding
0.60	GO:0008616	queuosine biosynthetic process
0.51	GO:0001525	angiogenesis
0.49	GO:0006915	apoptotic process
0.40	GO:0016032	viral process

0.81	GO:0043184	vascular endothelial growth factor receptor 2 binding
0.77	GO:0044183	protein binding involved in protein folding
0.64	GO:0008479	queuine tRNA-ribosyltransferase activity
0.35	GO:0051287	NAD binding

0.62	GO:0005829	cytosol
0.56	GO:0005634	nucleus

0.64

EC:2.4.2.29

GO:0008479

tr|Q6P271|Q6P271_DANRE
Sodium/potassium-transporting ATPase subunit alpha
Search

ATP1A3

0.64	Sodium/potassium-transporting ATPase subunit alpha

0.85	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.76	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.55	GO:0007626	locomotory behavior
0.53	GO:0006883	cellular sodium ion homeostasis
0.52	GO:0086036	regulation of cardiac muscle cell membrane potential
0.51	GO:1990535	neuron projection maintenance
0.51	GO:0008542	visual learning
0.51	GO:0140115	export across plasma membrane

0.85	GO:0005391	sodium:potassium-exchanging ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0046872	metal ion binding
0.49	GO:0001540	amyloid-beta binding
0.47	GO:0051087	chaperone binding
0.44	GO:1901681	sulfur compound binding
0.40	GO:1990239	steroid hormone binding

0.51	GO:0042383	sarcolemma
0.51	GO:0005890	sodium:potassium-exchanging ATPase complex
0.50	GO:0043209	myelin sheath
0.47	GO:0043025	neuronal cell body
0.47	GO:0030424	axon
0.45	GO:0005794	Golgi apparatus
0.44	GO:0005783	endoplasmic reticulum
0.41	GO:0005634	nucleus
0.40	GO:0045202	synapse
0.38	GO:0098590	plasma membrane region

0.85

EC:3.6.3.9

GO:0005391

tr|Q6P295|Q6P295_DANRE
Paired related homeobox 1b
Search

PRRX1

0.97	Paired mesoderm homeobox protein 1

0.65	GO:0007275	multicellular organism development
0.57	GO:1904888	cranial skeletal system development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0002053	positive regulation of mesenchymal cell proliferation
0.54	GO:0097150	neuronal stem cell population maintenance
0.54	GO:0045880	positive regulation of smoothened signaling pathway
0.53	GO:0060021	palate development
0.53	GO:0001709	cell fate determination

0.65	GO:0043565	sequence-specific DNA binding
0.55	GO:0071837	HMG box domain binding
0.54	GO:0001105	RNA polymerase II transcription coactivator activity
0.53	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.46	GO:0005829	cytosol
0.45	GO:0031974	membrane-enclosed lumen
0.41	GO:0044446	intracellular organelle part

tr|Q6P296|Q6P296_DANRE
Hexosyltransferase
Search

CHSY1

0.55	Hexosyltransferase

0.57	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process
0.54	GO:0051216	cartilage development
0.52	GO:0030204	chondroitin sulfate metabolic process
0.52	GO:0009887	animal organ morphogenesis
0.52	GO:0030279	negative regulation of ossification
0.51	GO:0045880	positive regulation of smoothened signaling pathway
0.51	GO:0009954	proximal/distal pattern formation
0.50	GO:0060348	bone development
0.50	GO:0051923	sulfation
0.47	GO:0048468	cell development

0.84	GO:0008376	acetylgalactosaminyltransferase activity
0.40	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity
0.35	GO:0008378	galactosyltransferase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0004252	serine-type endopeptidase activity

0.81	GO:0032580	Golgi cisterna membrane
0.44	GO:0005576	extracellular region
0.36	GO:0030176	integral component of endoplasmic reticulum membrane

0.84

GO:0008376

sp|Q6P298|NUBP1_DANRE
Cytosolic Fe-S cluster assembly factor nubp1
Search

NUBP1

0.88	Cytosolic Fe-S cluster assembly factor nubp1-B

0.67	GO:0016226	iron-sulfur cluster assembly
0.55	GO:0072697	protein localization to cell cortex
0.54	GO:0051642	centrosome localization
0.54	GO:0010826	negative regulation of centrosome duplication
0.51	GO:0016049	cell growth
0.49	GO:0006879	cellular iron ion homeostasis
0.37	GO:0030030	cell projection organization
0.36	GO:0002098	tRNA wobble uridine modification

0.61	GO:0051539	4 iron, 4 sulfur cluster binding
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0032555	purine ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0046872	metal ion binding
0.34	GO:0016887	ATPase activity
0.34	GO:0005515	protein binding

0.49	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.39	GO:0005814	centriole
0.38	GO:0005929	cilium
0.37	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.35	GO:1904949	ATPase complex
0.34	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016887

sp|Q6P2A1|PRDM9_DANRE
Histone-lysine N-methyltransferase PRDM9
Search

0.10	Histone-lysine N-methyltransferase PRDM9

0.40	GO:1903506	regulation of nucleic acid-templated transcription
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression
0.38	GO:0032259	methylation
0.36	GO:0006351	transcription, DNA-templated
0.33	GO:0016570	histone modification
0.33	GO:0018205	peptidyl-lysine modification
0.33	GO:0008213	protein alkylation
0.33	GO:0051321	meiotic cell cycle

0.51	GO:0003676	nucleic acid binding
0.40	GO:0046872	metal ion binding
0.38	GO:0008168	methyltransferase activity
0.38	GO:0003700	DNA binding transcription factor activity
0.32	GO:0140096	catalytic activity, acting on a protein

0.39	GO:0005634	nucleus
0.32	GO:0005694	chromosome

0.38

GO:0008168

tr|Q6P2A9|Q6P2A9_DANRE
Far upstream element (FUSE) binding protein 1
Search

FUBP1

0.88	Far upstream element-binding protein 1

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:0010604	positive regulation of macromolecule metabolic process
0.37	GO:0071425	hematopoietic stem cell proliferation
0.36	GO:0017145	stem cell division
0.36	GO:0006366	transcription by RNA polymerase II
0.36	GO:0016049	cell growth
0.35	GO:0045935	positive regulation of nucleobase-containing compound metabolic process
0.35	GO:0031328	positive regulation of cellular biosynthetic process

0.59	GO:0003723	RNA binding
0.37	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.34	GO:0005515	protein binding
0.34	GO:0003697	single-stranded DNA binding

0.44	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

tr|Q6P2B0|Q6P2B0_DANRE
VAMP (vesicle-associated membrane protein)-associated protein B and C
Search

VAPB

0.96	Vesicle-associated membrane protein, associated protein B and C

0.67	GO:0006987	activation of signaling protein activity involved in unfolded protein response
0.65	GO:0045070	positive regulation of viral genome replication
0.63	GO:0006874	cellular calcium ion homeostasis
0.61	GO:0090114	COPII-coated vesicle budding
0.61	GO:0007029	endoplasmic reticulum organization
0.55	GO:0036269	swimming behavior
0.53	GO:0019048	modulation by virus of host morphology or physiology
0.36	GO:0044791	positive regulation by host of viral release from host cell
0.36	GO:0044793	negative regulation by host of viral process
0.36	GO:0044827	modulation by host of viral genome replication

0.67	GO:0033149	FFAT motif binding
0.62	GO:0048487	beta-tubulin binding
0.61	GO:0045296	cadherin binding
0.57	GO:0042803	protein homodimerization activity
0.57	GO:0008017	microtubule binding
0.57	GO:0046982	protein heterodimerization activity
0.54	GO:0019899	enzyme binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.58	GO:0005794	Golgi apparatus
0.54	GO:0098588	bounding membrane of organelle
0.35	GO:0005923	bicellular tight junction
0.35	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0031982	vesicle
0.34	GO:0015630	microtubule cytoskeleton
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q6P2T0|TM38A_DANRE
Trimeric intracellular cation channel type A
Search

TMEM38A

0.97	Transmembrane protein 38A

0.62	GO:0015672	monovalent inorganic cation transport
0.61	GO:0098655	cation transmembrane transport
0.44	GO:0030001	metal ion transport
0.42	GO:0098660	inorganic ion transmembrane transport
0.30	GO:0009987	cellular process

0.74	GO:0005261	cation channel activity
0.46	GO:0015079	potassium ion transmembrane transporter activity
0.46	GO:0022839	ion gated channel activity
0.46	GO:0008381	mechanosensitive ion channel activity

0.30

GO:0031224

intrinsic component of membrane

tr|Q6P2T1|Q6P2T1_DANRE
Small nuclear ribonucleoprotein polypeptide A
Search

SNRPA

0.91	Small nuclear ribonucleoprotein polypeptide A

0.46	GO:0000398	mRNA splicing, via spliceosome
0.39	GO:1900363	regulation of mRNA polyadenylation

0.58	GO:0003723	RNA binding
0.50	GO:0042802	identical protein binding
0.39	GO:1990446	U1 snRNP binding

0.60	GO:0019013	viral nucleocapsid
0.56	GO:0030529	intracellular ribonucleoprotein complex
0.54	GO:0120114	Sm-like protein family complex
0.49	GO:0044428	nuclear part
0.48	GO:0031974	membrane-enclosed lumen
0.30	GO:0016020	membrane

tr|Q6P2T2|Q6P2T2_DANRE
Myozenin 2
Search

MYOZ2

0.95	Calsarcin 1

0.69	GO:0030239	myofibril assembly
0.37	GO:0016579	protein deubiquitination

0.87	GO:0031433	telethonin binding
0.76	GO:0051373	FATZ binding
0.73	GO:0003779	actin binding
0.40	GO:0030346	protein phosphatase 2B binding
0.37	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity

0.83	GO:0030018	Z disc
0.73	GO:0015629	actin cytoskeleton
0.35	GO:0031143	pseudopodium
0.33	GO:0005634	nucleus

0.37

EC:3.4.19.12

GO:0036459

tr|Q6P2T4|Q6P2T4_DANRE
RAD1 homolog (S. pombe)
Search

RAD1

0.92	Cell cycle checkpoint protein RAD1

0.81	GO:0000077	DNA damage checkpoint
0.58	GO:0051598	meiotic recombination checkpoint
0.56	GO:0071479	cellular response to ionizing radiation
0.48	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.43	GO:0006281	DNA repair
0.37	GO:0021762	substantia nigra development
0.35	GO:1901796	regulation of signal transduction by p53 class mediator
0.33	GO:0006260	DNA replication

0.52	GO:0008408	3'-5' exonuclease activity
0.45	GO:0003684	damaged DNA binding
0.39	GO:0008853	exodeoxyribonuclease III activity
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.49	GO:0031974	membrane-enclosed lumen
0.49	GO:0005694	chromosome
0.44	GO:0044446	intracellular organelle part
0.41	GO:0043234	protein complex

0.39

EC:3.1.11.2

GO:0008853

tr|Q6P2T5|Q6P2T5_DANRE
Arp2/3 complex 34 kDa subunit
Search

ARPC2

0.67	Actin-related protein 2/3 complex subunit 2

0.83	GO:0030041	actin filament polymerization
0.81	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.52	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.51	GO:0010592	positive regulation of lamellipodium assembly
0.41	GO:0030866	cortical actin cytoskeleton organization
0.39	GO:0000902	cell morphogenesis
0.39	GO:0030031	cell projection assembly
0.38	GO:0008360	regulation of cell shape
0.36	GO:1905924	regulation of invadopodium assembly
0.36	GO:2000814	positive regulation of barbed-end actin filament capping

0.73	GO:0003779	actin binding
0.50	GO:0005200	structural constituent of cytoskeleton
0.49	GO:0032403	protein complex binding
0.35	GO:0035254	glutamate receptor binding
0.35	GO:0051117	ATPase binding
0.35	GO:0019894	kinesin binding
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0016779	nucleotidyltransferase activity

0.80	GO:0005885	Arp2/3 protein complex
0.54	GO:0036195	muscle cell projection membrane
0.49	GO:0005925	focal adhesion
0.49	GO:0031252	cell leading edge
0.49	GO:0005737	cytoplasm
0.46	GO:0031982	vesicle
0.44	GO:0012505	endomembrane system
0.38	GO:0043005	neuron projection
0.38	GO:0045202	synapse
0.37	GO:0043230	extracellular organelle

0.33

EC:2.7.7

GO:0016779

tr|Q6P2T6|Q6P2T6_DANRE
Cysteine and glycine-rich protein 2
Search

CSRP2

0.90	Cysteine and glycine-rich protein 2

0.38	GO:0032501	multicellular organismal process
0.38	GO:0030154	cell differentiation
0.38	GO:0048856	anatomical structure development
0.36	GO:0034109	homotypic cell-cell adhesion
0.36	GO:0007599	hemostasis
0.35	GO:0042060	wound healing
0.35	GO:0001775	cell activation
0.33	GO:0030036	actin cytoskeleton organization

0.53	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.42	GO:0005925	focal adhesion
0.40	GO:0005634	nucleus
0.40	GO:0097517	contractile actin filament bundle
0.40	GO:0042641	actomyosin
0.39	GO:0031252	cell leading edge
0.35	GO:0070062	extracellular exosome
0.34	GO:0005737	cytoplasm
0.33	GO:0031974	membrane-enclosed lumen

sp|Q6P2T7|CD033_DANRE
UPF0462 protein C4orf33 homolog
Search

0.44	GO:0005515	protein binding
0.37	GO:0046872	metal ion binding

0.30

GO:0044425

membrane part

tr|Q6P2T9|Q6P2T9_DANRE
Tetraspanin
Search

CD63

0.58	Tetraspanin

0.48	GO:0035188	hatching
0.42	GO:0007166	cell surface receptor signaling pathway
0.35	GO:0072659	protein localization to plasma membrane
0.34	GO:0051604	protein maturation
0.33	GO:0046854	phosphatidylinositol phosphorylation
0.32	GO:0006468	protein phosphorylation

0.34	GO:0019899	enzyme binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005887	integral component of plasma membrane
0.35	GO:0097197	tetraspanin-enriched microdomain
0.34	GO:0009986	cell surface

tr|Q6P2U5|Q6P2U5_DANRE
ADP-ribosylation factor 6a
Search

ARF6

0.68	ADP-ribosylation factor

0.56	GO:0035020	regulation of Rac protein signal transduction
0.56	GO:0036010	protein localization to endosome
0.56	GO:0033028	myeloid cell apoptotic process
0.56	GO:0001889	liver development
0.55	GO:0097178	ruffle assembly
0.55	GO:0097284	hepatocyte apoptotic process
0.54	GO:0051489	regulation of filopodium assembly
0.53	GO:0034394	protein localization to cell surface
0.53	GO:0032456	endocytic recycling
0.53	GO:0060998	regulation of dendritic spine development

0.66	GO:0005525	GTP binding
0.56	GO:0031996	thioesterase binding
0.52	GO:0047485	protein N-terminus binding
0.36	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity
0.35	GO:0031681	G-protein beta-subunit binding
0.34	GO:0003924	GTPase activity

0.56	GO:0031527	filopodium membrane
0.56	GO:0090543	Flemming body
0.55	GO:0032154	cleavage furrow
0.55	GO:0055038	recycling endosome membrane
0.53	GO:0001726	ruffle
0.52	GO:0030139	endocytic vesicle
0.51	GO:0043209	myelin sheath
0.50	GO:0005938	cell cortex
0.39	GO:0005769	early endosome
0.38	GO:0005829	cytosol

0.36

EC:2.4.2.31

GO:0003956

tr|Q6P2U7|Q6P2U7_DANRE
Na(+)/H(+) exchange regulatory cofactor NHE-RF
Search

0.85	Na(+)/H(+) exchange regulatory cofactor NHE-RF

0.57	GO:0097291	renal phosphate ion absorption
0.57	GO:0032416	negative regulation of sodium:proton antiporter activity
0.56	GO:0032782	bile acid secretion
0.55	GO:0003096	renal sodium ion transport
0.55	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling
0.55	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway
0.55	GO:0048839	inner ear development
0.55	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway
0.55	GO:0044062	regulation of excretion
0.55	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway

0.81	GO:0032947	protein complex scaffold activity
0.56	GO:0031698	beta-2 adrenergic receptor binding
0.55	GO:0050780	dopamine receptor binding
0.55	GO:0017081	chloride channel regulator activity
0.52	GO:0043621	protein self-association
0.52	GO:0030165	PDZ domain binding
0.52	GO:0019902	phosphatase binding
0.52	GO:0008013	beta-catenin binding
0.51	GO:0070851	growth factor receptor binding
0.40	GO:0045159	myosin II binding

0.62	GO:0012505	endomembrane system
0.54	GO:0097225	sperm midpiece
0.54	GO:0032426	stereocilium tip
0.53	GO:0031526	brush border membrane
0.53	GO:0005902	microvillus
0.51	GO:0016324	apical plasma membrane
0.50	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0030175	filopodium
0.39	GO:0001726	ruffle
0.38	GO:0098857	membrane microdomain

0.33

EC:3.1.3.3

GO:0004647

sp|Q6P2U9|CSN3_DANRE
COP9 signalosome complex subunit 3
Search

COPS3

0.88	COP9 constitutive photomorphogenic subunit 3

0.56	GO:0000338	protein deneddylation
0.51	GO:0001701	in utero embryonic development
0.44	GO:0006511	ubiquitin-dependent protein catabolic process
0.35	GO:0043687	post-translational protein modification
0.34	GO:0000715	nucleotide-excision repair, DNA damage recognition
0.34	GO:0006283	transcription-coupled nucleotide-excision repair
0.34	GO:0009416	response to light stimulus
0.33	GO:0065009	regulation of molecular function
0.33	GO:0007165	signal transduction

0.35	GO:0005515	protein binding
0.33	GO:0098772	molecular function regulator
0.30	GO:0003824	catalytic activity

0.78	GO:0008180	COP9 signalosome
0.49	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol

tr|Q6P2V0|Q6P2V0_DANRE
Zgc:77614
Search

0.41	GO:0016567	protein ubiquitination
0.40	GO:0006397	mRNA processing

0.63	GO:0008270	zinc ion binding
0.42	GO:0003676	nucleic acid binding
0.41	GO:0004842	ubiquitin-protein transferase activity
0.41	GO:0061659	ubiquitin-like protein ligase activity
0.37	GO:0016874	ligase activity

0.61	GO:0005634	nucleus
0.30	GO:0044425	membrane part

0.37	EC:6	GO:0016874
0.41	KEGG:R03876	GO:0004842

tr|Q6P2V4|Q6P2V4_DANRE
Hgd protein
Search

HGD

0.60	LOW QUALITY PROTEIN: homogentisate 1,2-dioxygenase

0.81	GO:1902222	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process
0.78	GO:0006570	tyrosine metabolic process
0.78	GO:0006558	L-phenylalanine metabolic process
0.76	GO:0009074	aromatic amino acid family catabolic process
0.71	GO:0042737	drug catabolic process
0.53	GO:0055114	oxidation-reduction process

0.82	GO:0004411	homogentisate 1,2-dioxygenase activity
0.49	GO:0042802	identical protein binding
0.33	GO:0046872	metal ion binding

0.37	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol

0.82	EC:1.13.11.5	GO:0004411
0.82	KEGG:R02519	GO:0004411

tr|Q6P3G1|Q6P3G1_DANRE
Ceruloplasmin
Search

0.70	Ceruloplasmin

0.78	GO:0006825	copper ion transport
0.76	GO:0006879	cellular iron ion homeostasis
0.53	GO:0055114	oxidation-reduction process

0.81	GO:0004322	ferroxidase activity
0.72	GO:0005507	copper ion binding
0.53	GO:0051087	chaperone binding

0.51	GO:0005615	extracellular space
0.39	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm

0.81

EC:1.16.3.1

GO:0004322

tr|Q6P3G2|Q6P3G2_DANRE
Sorting nexin family member 27
Search

SNX27

0.95	Sorting nexin family member 27 (Predicted)

0.73	GO:0016197	endosomal transport
0.68	GO:0006886	intracellular protein transport
0.60	GO:0007165	signal transduction
0.54	GO:0098876	vesicle-mediated transport to the plasma membrane
0.51	GO:0007041	lysosomal transport
0.36	GO:0001770	establishment of natural killer cell polarity
0.34	GO:0007399	nervous system development
0.33	GO:0042493	response to drug
0.33	GO:0006457	protein folding
0.32	GO:0006950	response to stress

0.82	GO:0032266	phosphatidylinositol-3-phosphate binding
0.35	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0001772	immunological synapse
0.53	GO:0005769	early endosome
0.53	GO:0071203	WASH complex
0.52	GO:0030904	retromer complex
0.47	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol
0.38	GO:0010008	endosome membrane
0.35	GO:0005856	cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

sp|Q6P3G4|CCSAP_DANRE
Centriole, cilia and spindle-associated protein
Search

CCSAP

0.96	Centriole, cilia and spindle-associated protein b

0.60	GO:1990755	mitotic spindle microtubule depolymerization
0.58	GO:0032886	regulation of microtubule-based process
0.57	GO:1902019	regulation of cilium-dependent cell motility
0.56	GO:0007346	regulation of mitotic cell cycle
0.53	GO:0048666	neuron development
0.53	GO:0045995	regulation of embryonic development
0.52	GO:1902115	regulation of organelle assembly
0.52	GO:0061371	determination of heart left/right asymmetry
0.52	GO:0051783	regulation of nuclear division
0.52	GO:0003341	cilium movement

0.50

GO:0008017

microtubule binding

0.69	GO:0005856	cytoskeleton
0.58	GO:0044441	ciliary part
0.54	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.54	GO:0030424	axon
0.49	GO:0099512	supramolecular fiber
0.46	GO:0044446	intracellular organelle part

tr|Q6P3G5|Q6P3G5_DANRE
AMP deaminase
Search

AMPD1

0.74	Adenosine monophosphate deaminase

0.79	GO:0032264	IMP salvage
0.39	GO:0097009	energy homeostasis
0.38	GO:0034101	erythrocyte homeostasis
0.37	GO:0046039	GTP metabolic process
0.37	GO:0046033	AMP metabolic process
0.36	GO:0046031	ADP metabolic process
0.36	GO:0010033	response to organic substance
0.35	GO:0046034	ATP metabolic process

0.84	GO:0003876	AMP deaminase activity
0.49	GO:0046872	metal ion binding
0.38	GO:0032036	myosin heavy chain binding

0.33

GO:0005829

cytosol

0.84

EC:3.5.4.6

GO:0003876

tr|Q6P3G9|Q6P3G9_DANRE
Endoplasmic reticulum protein 44
Search

ERP44

0.96	Thioredoxin domain containing 4 (Endoplasmic reticulum)

0.68	GO:0045454	cell redox homeostasis
0.54	GO:0034976	response to endoplasmic reticulum stress
0.53	GO:0006986	response to unfolded protein
0.49	GO:0009100	glycoprotein metabolic process
0.49	GO:0006457	protein folding
0.46	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling
0.43	GO:0007507	heart development
0.35	GO:0043312	neutrophil degranulation

0.55	GO:0003756	protein disulfide isomerase activity
0.34	GO:0005515	protein binding

0.54	GO:0005788	endoplasmic reticulum lumen
0.53	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.50	GO:0009986	cell surface
0.49	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0035580	specific granule lumen
0.30	GO:0031224	intrinsic component of membrane

0.55

EC:5.3.4.1

GO:0003756

tr|Q6P3H0|Q6P3H0_DANRE
Zinc finger protein 36, C3H type-like 1 like
Search

ZFP36L1

0.97	ZFP36 ring finger protein like 1

0.78	GO:1904582	positive regulation of intracellular mRNA localization
0.78	GO:0061158	3'-UTR-mediated mRNA destabilization
0.77	GO:0097403	cellular response to raffinose
0.77	GO:1902172	regulation of keratinocyte apoptotic process
0.76	GO:1904628	cellular response to phorbol 13-acetate 12-myristate
0.76	GO:0045657	positive regulation of monocyte differentiation
0.76	GO:0045647	negative regulation of erythrocyte differentiation
0.75	GO:0070371	ERK1 and ERK2 cascade
0.75	GO:0003343	septum transversum development
0.74	GO:0071364	cellular response to epidermal growth factor stimulus

0.76	GO:0035925	mRNA 3'-UTR AU-rich region binding
0.74	GO:0071889	14-3-3 protein binding
0.54	GO:0046872	metal ion binding

0.68	GO:0000932	P-body
0.54	GO:0005634	nucleus
0.47	GO:0005829	cytosol

tr|Q6P3H1|Q6P3H1_DANRE
Palmitoyltransferase
Search

0.52	Palmitoyltransferase

0.45	GO:0018231	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine
0.45	GO:0048733	sebaceous gland development
0.44	GO:0018345	protein palmitoylation
0.42	GO:0001942	hair follicle development
0.33	GO:0006420	arginyl-tRNA aminoacylation
0.33	GO:0050999	regulation of nitric-oxide synthase activity
0.32	GO:0055114	oxidation-reduction process

0.79	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.33	GO:0004814	arginine-tRNA ligase activity
0.33	GO:0004792	thiosulfate sulfurtransferase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016491	oxidoreductase activity

0.43	GO:0012505	endomembrane system
0.39	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0044444	cytoplasmic part
0.36	GO:0005886	plasma membrane
0.32	GO:0098588	bounding membrane of organelle
0.32	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.79	EC:2.3.1.225	GO:0019706
0.33	KEGG:R01931	GO:0004792

sp|Q6P3H4|PNCB_DANRE
Nicotinate phosphoribosyltransferase
Search

NAPRT

0.46	Nicotinate phosphoribosyltransferase

0.79	GO:0019358	nicotinate nucleotide salvage
0.72	GO:0009435	NAD biosynthetic process
0.48	GO:0006979	response to oxidative stress
0.36	GO:0043312	neutrophil degranulation

0.78	GO:0004516	nicotinate phosphoribosyltransferase activity
0.76	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity
0.34	GO:0004427	inorganic diphosphatase activity
0.34	GO:0005515	protein binding
0.33	GO:0000287	magnesium ion binding

0.47	GO:0005829	cytosol
0.36	GO:0035578	azurophil granule lumen
0.35	GO:0070062	extracellular exosome

0.78	EC:2.4.2.11	GO:0004516
0.78	KEGG:R01724	GO:0004516

sp|Q6P3H7|RBBP4_DANRE
Histone-binding protein RBBP4
Search

RBBP4

0.88	RB binding protein 4, chromatin remodeling factor

0.49	GO:0006335	DNA replication-dependent nucleosome assembly
0.47	GO:0006336	DNA replication-independent nucleosome assembly
0.46	GO:0006338	chromatin remodeling
0.40	GO:0016569	covalent chromatin modification
0.39	GO:0006260	DNA replication
0.38	GO:0007049	cell cycle
0.38	GO:0060416	response to growth hormone
0.37	GO:0006351	transcription, DNA-templated
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.47	GO:0042826	histone deacetylase binding
0.43	GO:0008094	DNA-dependent ATPase activity
0.36	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.36	GO:0031492	nucleosomal DNA binding
0.36	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0004407	histone deacetylase activity
0.34	GO:0042393	histone binding

0.61	GO:0005634	nucleus
0.52	GO:0033186	CAF-1 complex
0.48	GO:0034708	methyltransferase complex
0.46	GO:0017053	transcriptional repressor complex
0.44	GO:0031974	membrane-enclosed lumen
0.43	GO:0000785	chromatin
0.42	GO:0005829	cytosol
0.41	GO:1904949	ATPase complex

0.34

GO:0004407

tr|Q6P3H8|Q6P3H8_DANRE
Rac GTPase-activating protein 1
Search

RACGAP1

0.80	Rac GTPase-activating protein 1

0.62	GO:0035556	intracellular signal transduction
0.58	GO:0000281	mitotic cytokinesis
0.55	GO:0051256	mitotic spindle midzone assembly
0.54	GO:0051988	regulation of attachment of spindle microtubules to kinetochore
0.53	GO:0044837	actomyosin contractile ring organization
0.53	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis
0.53	GO:0007405	neuroblast proliferation
0.53	GO:0032467	positive regulation of cytokinesis
0.51	GO:0045995	regulation of embryonic development
0.51	GO:0043087	regulation of GTPase activity

0.54	GO:0043014	alpha-tubulin binding
0.54	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.53	GO:0048487	beta-tubulin binding
0.52	GO:0043015	gamma-tubulin binding
0.51	GO:0046872	metal ion binding
0.50	GO:0019901	protein kinase binding
0.49	GO:0005096	GTPase activator activity
0.49	GO:0008017	microtubule binding
0.32	GO:0003677	DNA binding

0.56	GO:0097149	centralspindlin complex
0.53	GO:0097610	cell surface furrow
0.53	GO:0051233	spindle midzone
0.52	GO:0030496	midbody
0.52	GO:0032155	cell division site part
0.51	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.47	GO:0005654	nucleoplasm
0.36	GO:0005737	cytoplasm
0.36	GO:0097223	sperm part
0.35	GO:0070062	extracellular exosome

tr|Q6P3H9|Q6P3H9_DANRE
Solute carrier family 3 (amino acid transporter heavy chain), member 2b
Search

SLC3A2

0.91	Neutral and basic amino acid transport protein rBAT

0.60	GO:0005975	carbohydrate metabolic process
0.48	GO:0060142	regulation of syncytium formation by plasma membrane fusion
0.43	GO:0060356	leucine import
0.40	GO:0015827	tryptophan transport
0.38	GO:0043330	response to exogenous dsRNA
0.34	GO:0050900	leukocyte migration
0.34	GO:0016049	cell growth
0.34	GO:1902475	L-alpha-amino acid transmembrane transport
0.34	GO:0035725	sodium ion transmembrane transport
0.34	GO:0006816	calcium ion transport

0.39	GO:0015175	neutral amino acid transmembrane transporter activity
0.37	GO:0045296	cadherin binding
0.36	GO:0003725	double-stranded RNA binding
0.34	GO:0005432	calcium:sodium antiporter activity
0.32	GO:0033942	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity

0.45	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.40	GO:0005886	plasma membrane
0.39	GO:0042470	melanosome
0.38	GO:0045177	apical part of cell
0.36	GO:0009986	cell surface
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.32

EC:3.2.1.141

GO:0033942

tr|Q6P3I0|Q6P3I0_DANRE
HEAT repeat containing 3
Search

HEATR3

0.97	HEAT repeat-containing protein 3

0.76	GO:0006606	protein import into nucleus
0.72	GO:0042273	ribosomal large subunit biogenesis
0.42	GO:0006730	one-carbon metabolic process
0.36	GO:0051090	regulation of DNA binding transcription factor activity

0.68	GO:0051082	unfolded protein binding
0.43	GO:0004089	carbonate dehydratase activity
0.40	GO:0016779	nucleotidyltransferase activity
0.39	GO:0008270	zinc ion binding

0.34

GO:0005634

nucleus

0.43

EC:4.2.1.1

GO:0004089

tr|Q6P3I6|Q6P3I6_DANRE
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
Search

CTDSP2

0.94	Carboxy-terminal domain RNA polymerase II polypeptide A small

0.68	GO:0016311	dephosphorylation
0.54	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.49	GO:0001933	negative regulation of protein phosphorylation
0.43	GO:0036211	protein modification process
0.41	GO:0044267	cellular protein metabolic process
0.41	GO:0030182	neuron differentiation
0.35	GO:0036498	IRE1-mediated unfolded protein response
0.33	GO:0007010	cytoskeleton organization

0.69	GO:0016791	phosphatase activity
0.42	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0051015	actin filament binding
0.34	GO:0046872	metal ion binding

0.35	GO:0005634	nucleus
0.34	GO:0070062	extracellular exosome
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.69

EC:3.1.3 EC:3.1.3.41

GO:0016791

tr|Q6P3I7|Q6P3I7_DANRE
ADP-ribosylation factor-like 4
Search

ARL4A

0.95	ADP-ribosylation factor-like protein 4A

0.51

GO:0050873

brown fat cell differentiation

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0003924	GTPase activity
0.34	GO:0005515	protein binding

0.46	GO:0005730	nucleolus
0.45	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane

tr|Q6P3I8|Q6P3I8_DANRE
Glutaryl-CoA dehydrogenase a
Search

GCDH

0.49	Glutaryl-CoA dehydrogenaseserine-threonine

0.53	GO:0055114	oxidation-reduction process
0.48	GO:0009062	fatty acid catabolic process
0.47	GO:0030258	lipid modification
0.39	GO:0046949	fatty-acyl-CoA biosynthetic process
0.37	GO:0006568	tryptophan metabolic process
0.34	GO:0006554	lysine catabolic process

0.73	GO:0003995	acyl-CoA dehydrogenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.38	GO:0000062	fatty-acyl-CoA binding
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

0.42	GO:0005739	mitochondrion
0.36	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0031090	organelle membrane
0.33	GO:0031975	envelope
0.30	GO:0016021	integral component of membrane

0.73

EC:1.3.99.3

GO:0003995

tr|Q6P3J0|Q6P3J0_DANRE
O-acyltransferase
Search

DGAT1

0.62	Diacylglycerol O-acyltransferase 1

0.80	GO:0019432	triglyceride biosynthetic process
0.53	GO:0034379	very-low-density lipoprotein particle assembly
0.52	GO:0055089	fatty acid homeostasis
0.52	GO:0046339	diacylglycerol metabolic process
0.51	GO:0035336	long-chain fatty-acyl-CoA metabolic process
0.50	GO:0019915	lipid storage
0.45	GO:0001878	response to yeast
0.40	GO:0042572	retinol metabolic process
0.36	GO:1901738	regulation of vitamin A metabolic process
0.35	GO:0044752	response to human chorionic gonadotropin

0.78	GO:0004144	diacylglycerol O-acyltransferase activity
0.53	GO:0003846	2-acylglycerol O-acyltransferase activity
0.42	GO:0050252	retinol O-fatty-acyltransferase activity
0.35	GO:0005504	fatty acid binding
0.35	GO:0019992	diacylglycerol binding
0.33	GO:0005515	protein binding
0.32	GO:0004672	protein kinase activity
0.31	GO:0005524	ATP binding

0.65	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0035579	specific granule membrane
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.78

EC:2.3.1.20

GO:0004144

tr|Q6P3J2|Q6P3J2_DANRE
Rho GDP dissociation inhibitor (GDI) alpha
Search

ARHGDIA

0.92	Rho GDP dissociation inhibitor alpha

0.69	GO:0050790	regulation of catalytic activity
0.50	GO:0071526	semaphorin-plexin signaling pathway
0.49	GO:0007266	Rho protein signal transduction
0.47	GO:0032879	regulation of localization
0.44	GO:2000249	regulation of actin cytoskeleton reorganization
0.42	GO:0040013	negative regulation of locomotion
0.42	GO:0035023	regulation of Rho protein signal transduction
0.41	GO:2000242	negative regulation of reproductive process
0.41	GO:0043901	negative regulation of multi-organism process
0.40	GO:0051093	negative regulation of developmental process

0.85	GO:0005094	Rho GDP-dissociation inhibitor activity
0.42	GO:0048365	Rac GTPase binding
0.38	GO:0005096	GTPase activator activity
0.38	GO:0003924	GTPase activity
0.37	GO:0051879	Hsp90 protein binding
0.37	GO:0005504	fatty acid binding
0.36	GO:0019901	protein kinase binding
0.36	GO:0003723	RNA binding

0.50	GO:0001772	immunological synapse
0.49	GO:0005737	cytoplasm
0.41	GO:0005634	nucleus
0.36	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.33	GO:0005856	cytoskeleton

tr|Q6P3J5|Q6P3J5_DANRE
Eukaryotic translation elongation factor 2
Search

EEF2

0.55	Eukaryotic translation elongation factor 2

0.65	GO:0006414	translational elongation
0.49	GO:0002244	hematopoietic progenitor cell differentiation
0.47	GO:0045727	positive regulation of translation
0.41	GO:0070887	cellular response to chemical stimulus
0.40	GO:0034341	response to interferon-gamma
0.40	GO:0051593	response to folic acid
0.40	GO:0014009	glial cell proliferation
0.39	GO:1990089	response to nerve growth factor
0.39	GO:0002931	response to ischemia
0.39	GO:0003009	skeletal muscle contraction

0.66	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0003746	translation elongation factor activity
0.64	GO:0032561	guanyl ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0045296	cadherin binding
0.47	GO:0019901	protein kinase binding
0.39	GO:0002039	p53 binding
0.38	GO:0008097	5S rRNA binding
0.38	GO:0051015	actin filament binding

0.50	GO:0016235	aggresome
0.48	GO:0005844	polysome
0.44	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane
0.38	GO:0045121	membrane raft
0.37	GO:0005634	nucleus
0.37	GO:0031012	extracellular matrix
0.37	GO:0070062	extracellular exosome
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0034774	secretory granule lumen

tr|Q6P3J6|Q6P3J6_DANRE
Peptidylprolyl isomerase
Search

FKBP8

0.46	Peptidyl-prolyl cis-trans isomerase FKBP8

0.75	GO:0021904	dorsal/ventral neural tube patterning
0.73	GO:0030513	positive regulation of BMP signaling pathway
0.71	GO:0035264	multicellular organism growth
0.71	GO:0001708	cell fate specification
0.70	GO:0007224	smoothened signaling pathway
0.68	GO:0043010	camera-type eye development
0.66	GO:0061077	chaperone-mediated protein folding
0.66	GO:0043066	negative regulation of apoptotic process
0.66	GO:0006915	apoptotic process
0.64	GO:0001933	negative regulation of protein phosphorylation

0.73	GO:0097718	disordered domain specific binding
0.72	GO:0005528	FK506 binding
0.63	GO:0042802	identical protein binding
0.62	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.40	GO:0046872	metal ion binding

0.66	GO:0030176	integral component of endoplasmic reticulum membrane
0.62	GO:0005829	cytosol
0.56	GO:0005739	mitochondrion
0.54	GO:0031967	organelle envelope
0.53	GO:0031090	organelle membrane
0.52	GO:0043234	protein complex

0.62

GO:0003755

tr|Q6P3J7|Q6P3J7_DANRE
EH-domain containing 2
Search

EHD2

0.86	EH domain-containing protein 2

0.72	GO:0032456	endocytic recycling
0.61	GO:0030036	actin cytoskeleton organization
0.60	GO:0072659	protein localization to plasma membrane
0.59	GO:2001137	positive regulation of endocytic recycling
0.57	GO:1901741	positive regulation of myoblast fusion
0.56	GO:0097320	plasma membrane tubulation
0.53	GO:0030865	cortical cytoskeleton organization
0.52	GO:1901387	positive regulation of voltage-gated calcium channel activity
0.52	GO:0086036	regulation of cardiac muscle cell membrane potential
0.51	GO:0090160	Golgi to lysosome transport

0.68	GO:0005509	calcium ion binding
0.65	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0019904	protein domain specific binding
0.50	GO:0042802	identical protein binding
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0008144	drug binding
0.34	GO:0008289	lipid binding

0.62	GO:0055038	recycling endosome membrane
0.58	GO:0048471	perinuclear region of cytoplasm
0.56	GO:0098590	plasma membrane region
0.55	GO:0045171	intercellular bridge
0.53	GO:0045121	membrane raft
0.52	GO:0020016	ciliary pocket
0.52	GO:0005829	cytosol
0.50	GO:0019898	extrinsic component of membrane
0.49	GO:0043209	myelin sheath
0.48	GO:0030139	endocytic vesicle

0.34

GO:0016787

tr|Q6P3J8|Q6P3J8_DANRE
L-threonine dehydrogenase
Search

TDH

0.69	L-threonine dehydrogenase

0.49	GO:0006567	threonine catabolic process
0.39	GO:0055114	oxidation-reduction process
0.37	GO:0006544	glycine metabolic process
0.36	GO:0042737	drug catabolic process

0.60	GO:0050662	coenzyme binding
0.51	GO:0008743	L-threonine 3-dehydrogenase activity
0.47	GO:0042802	identical protein binding

0.42	GO:0005739	mitochondrion
0.32	GO:0019866	organelle inner membrane

0.51	EC:1.1.1.103	GO:0008743
0.51	KEGG:R01465	GO:0008743

tr|Q6P3J9|Q6P3J9_DANRE
Adenosine kinase a
Search

ADK

0.63	Adenosine kinase a

0.74	GO:0006166	purine ribonucleoside salvage
0.73	GO:0006167	AMP biosynthetic process
0.56	GO:0006175	dATP biosynthetic process
0.52	GO:0016310	phosphorylation
0.48	GO:0046086	adenosine biosynthetic process
0.41	GO:0044262	cellular carbohydrate metabolic process
0.37	GO:0032261	purine nucleotide salvage
0.35	GO:0044342	type B pancreatic cell proliferation
0.35	GO:0010613	positive regulation of cardiac muscle hypertrophy
0.35	GO:0032922	circadian regulation of gene expression

0.83	GO:0004001	adenosine kinase activity
0.43	GO:0019200	carbohydrate kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046872	metal ion binding
0.34	GO:0003723	RNA binding

0.47	GO:0005829	cytosol
0.46	GO:0005654	nucleoplasm

0.83

EC:2.7.1.20

GO:0004001

sp|Q6P3K3|FBX9_DANRE
F-box only protein 9
Search

FBXO9

0.94	F-box only protein 9

0.84	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.82	GO:0045444	fat cell differentiation
0.79	GO:0032006	regulation of TOR signaling
0.76	GO:0045087	innate immune response
0.72	GO:0016567	protein ubiquitination
0.40	GO:0043687	post-translational protein modification

0.44	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0003924	GTPase activity
0.37	GO:0032550	purine ribonucleoside binding
0.36	GO:0032561	guanyl ribonucleotide binding
0.36	GO:0005515	protein binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.83	GO:0019005	SCF ubiquitin ligase complex
0.48	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.44

GO:0004842

sp|Q6P3K7|KC1DB_DANRE
Casein kinase I isoform delta-B
Search

CSNK1D

0.75	Casein kinase I

0.62	GO:0006468	protein phosphorylation
0.52	GO:2000052	positive regulation of non-canonical Wnt signaling pathway
0.51	GO:0018209	peptidyl-serine modification
0.51	GO:0032922	circadian regulation of gene expression
0.50	GO:0071539	protein localization to centrosome
0.50	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.50	GO:0061512	protein localization to cilium
0.50	GO:1905515	non-motile cilium assembly
0.50	GO:0042752	regulation of circadian rhythm
0.50	GO:0034067	protein localization to Golgi apparatus

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0045296	cadherin binding
0.37	GO:0042277	peptide binding

0.49	GO:0005876	spindle microtubule
0.48	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005813	centrosome
0.45	GO:0005794	Golgi apparatus
0.43	GO:0005634	nucleus
0.39	GO:0005886	plasma membrane
0.37	GO:0043005	neuron projection
0.35	GO:0098588	bounding membrane of organelle
0.34	GO:0005829	cytosol
0.34	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment

sp|Q6P3L0|MVP_DANRE
Major vault protein
Search

MVP

0.88	major vault protein isoform X2

0.49	GO:0031953	negative regulation of protein autophosphorylation
0.48	GO:0061099	negative regulation of protein tyrosine kinase activity
0.47	GO:0038127	ERBB signaling pathway
0.46	GO:0023051	regulation of signaling
0.41	GO:0031102	neuron projection regeneration
0.39	GO:0001654	eye development
0.39	GO:0007420	brain development

0.47	GO:0019903	protein phosphatase binding
0.45	GO:0019901	protein kinase binding
0.44	GO:0042802	identical protein binding

0.61	GO:0030529	intracellular ribonucleoprotein complex
0.49	GO:0005737	cytoplasm
0.46	GO:0005634	nucleus
0.42	GO:0005856	cytoskeleton

tr|Q6P3L3|Q6P3L3_DANRE
Heat shock protein 5
Search

HSPA5

0.71	Glucose-regulated protein 78

0.53	GO:1903895	negative regulation of IRE1-mediated unfolded protein response
0.53	GO:0090074	negative regulation of protein homodimerization activity
0.50	GO:0035437	maintenance of protein localization in endoplasmic reticulum
0.49	GO:0030335	positive regulation of cell migration
0.48	GO:0021589	cerebellum structural organization
0.48	GO:0006987	activation of signaling protein activity involved in unfolded protein response
0.47	GO:0006983	ER overload response
0.47	GO:0071353	cellular response to interleukin-4
0.46	GO:0021680	cerebellar Purkinje cell layer development
0.46	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0051787	misfolded protein binding
0.45	GO:0045296	cadherin binding
0.44	GO:0019904	protein domain specific binding
0.44	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0016887	ATPase activity
0.43	GO:0043022	ribosome binding

0.52	GO:0005788	endoplasmic reticulum lumen
0.47	GO:0042470	melanosome
0.47	GO:0034663	endoplasmic reticulum chaperone complex
0.45	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.45	GO:0030496	midbody
0.45	GO:0043209	myelin sheath
0.44	GO:0030176	integral component of endoplasmic reticulum membrane
0.44	GO:0008180	COP9 signalosome
0.43	GO:0009986	cell surface
0.42	GO:0005790	smooth endoplasmic reticulum

0.43

GO:0016887

sp|Q6P3L6|DH12A_DANRE
Very-long-chain 3-oxoacyl-CoA reductase-A
Search

HSD17B12

0.71	Very-long-chain 3-oxoacyl-CoA reductase-A

0.49	GO:0055114	oxidation-reduction process
0.49	GO:0010811	positive regulation of cell-substrate adhesion
0.47	GO:0030198	extracellular matrix organization
0.46	GO:0006703	estrogen biosynthetic process
0.41	GO:0006633	fatty acid biosynthetic process
0.35	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.33	GO:0010951	negative regulation of endopeptidase activity
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression

0.50	GO:0016491	oxidoreductase activity
0.50	GO:0001968	fibronectin binding
0.48	GO:0005518	collagen binding
0.48	GO:0008201	heparin binding
0.33	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0050661	NADP binding
0.32	GO:0050660	flavin adenine dinucleotide binding
0.32	GO:0003735	structural constituent of ribosome

0.45	GO:0005578	proteinaceous extracellular matrix
0.41	GO:0005789	endoplasmic reticulum membrane
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.50

GO:0016491

tr|Q6P3L9|Q6P3L9_DANRE
Glutamate dehydrogenase 1
Search

0.44	Glutamate dehydrogenase

0.60	GO:0006520	cellular amino acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0032024	positive regulation of insulin secretion
0.45	GO:0072350	tricarboxylic acid metabolic process
0.40	GO:0043649	dicarboxylic acid catabolic process
0.40	GO:0032094	response to food
0.38	GO:0043650	dicarboxylic acid biosynthetic process
0.38	GO:1901565	organonitrogen compound catabolic process
0.37	GO:0021762	substantia nigra development
0.37	GO:0010044	response to aluminum ion

0.76	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
0.42	GO:0070728	leucine binding
0.39	GO:0043531	ADP binding
0.39	GO:0032550	purine ribonucleoside binding
0.38	GO:0019001	guanyl nucleotide binding
0.37	GO:0070403	NAD+ binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.35	GO:0008144	drug binding

0.48	GO:0005759	mitochondrial matrix
0.41	GO:0031966	mitochondrial membrane
0.41	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.76

EC:1.4.1

GO:0016639

tr|Q6P3M0|Q6P3M0_DANRE
Solute carrier family 30 (Zinc transporter), member 1
Search

SLC30A1

0.78	Zinc transporter 1

0.58	GO:0071584	negative regulation of zinc ion transmembrane import
0.56	GO:0098655	cation transmembrane transport
0.55	GO:0090281	negative regulation of calcium ion import
0.54	GO:0006829	zinc II ion transport
0.54	GO:0006882	cellular zinc ion homeostasis
0.51	GO:0006874	cellular calcium ion homeostasis
0.51	GO:0001701	in utero embryonic development
0.50	GO:0061088	regulation of sequestering of zinc ion
0.49	GO:0010043	response to zinc ion
0.47	GO:0065009	regulation of molecular function

0.59	GO:0019855	calcium channel inhibitor activity
0.56	GO:0008324	cation transmembrane transporter activity
0.41	GO:0015318	inorganic molecular entity transmembrane transporter activity
0.33	GO:0005515	protein binding

0.51	GO:0031965	nuclear membrane
0.50	GO:0005794	Golgi apparatus
0.49	GO:0005783	endoplasmic reticulum
0.43	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q6P402|CEP89_DANRE
Centrosomal protein of 89 kDa
Search

CEP89

0.86	Centrosomal protein of 89 kDa

0.79	GO:0060271	cilium assembly
0.77	GO:0007268	chemical synaptic transmission
0.75	GO:0007005	mitochondrion organization
0.35	GO:0140056	organelle localization by membrane tethering
0.32	GO:0055085	transmembrane transport

0.34	GO:0005515	protein binding
0.32	GO:0022857	transmembrane transporter activity

0.82	GO:0005814	centriole
0.58	GO:0097539	ciliary transition fiber
0.56	GO:0000922	spindle pole
0.56	GO:0097730	non-motile cilium
0.55	GO:0005813	centrosome
0.54	GO:0031514	motile cilium
0.50	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane
0.41	GO:0005758	mitochondrial intermembrane space
0.30	GO:0031224	intrinsic component of membrane

sp|Q6P4P2|LMD2B_DANRE
LMBR1 domain-containing protein 2-B
Search

LMBRD2

0.96	LMBR1 domain-containing protein 2-B

0.30

GO:0008152

metabolic process

0.32

GO:0016758

transferase activity, transferring hexosyl groups

0.30

GO:0044425

membrane part

0.32

GO:0016758

tr|Q6P4P6|Q6P4P6_DANRE
HMP19 protein
Search

HGNC:24955

0.95	Neuronal vesicle trafficking-associated protein 2

0.85	GO:0007212	dopamine receptor signaling pathway
0.83	GO:0048268	clathrin coat assembly
0.48	GO:0016197	endosomal transport
0.41	GO:0099627	neurotransmitter receptor cycle
0.40	GO:1903540	establishment of protein localization to postsynaptic membrane
0.40	GO:0098877	neurotransmitter receptor transport to plasma membrane
0.40	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels
0.40	GO:0042982	amyloid precursor protein metabolic process
0.40	GO:0001881	receptor recycling
0.39	GO:0097120	receptor localization to synapse

0.85	GO:0032051	clathrin light chain binding
0.34	GO:0003730	mRNA 3'-UTR binding
0.34	GO:0045182	translation regulator activity
0.34	GO:0003677	DNA binding

0.50	GO:1990674	Golgi cis cisterna membrane
0.49	GO:0005768	endosome
0.44	GO:0030659	cytoplasmic vesicle membrane
0.43	GO:0098805	whole membrane
0.41	GO:0043202	lysosomal lumen
0.40	GO:0030425	dendrite
0.39	GO:0032588	trans-Golgi network membrane
0.39	GO:0016328	lateral plasma membrane
0.38	GO:0098794	postsynapse
0.38	GO:0097060	synaptic membrane

sp|Q6P4U6|ZNRF1_DANRE
E3 ubiquitin-protein ligase znrf1
Search

ZNRF1

0.83	Zinc and ring finger 1

0.58	GO:0070936	protein K48-linked ubiquitination
0.56	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.41	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.35	GO:0007010	cytoskeleton organization
0.33	GO:0006355	regulation of transcription, DNA-templated
0.32	GO:0055114	oxidation-reduction process

0.57	GO:0061630	ubiquitin protein ligase activity
0.53	GO:0016874	ligase activity
0.37	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding
0.34	GO:0004499	N,N-dimethylaniline monooxygenase activity
0.32	GO:0003676	nucleic acid binding

0.54	GO:0031410	cytoplasmic vesicle
0.49	GO:0012505	endomembrane system
0.49	GO:0005829	cytosol
0.46	GO:0012506	vesicle membrane
0.43	GO:0005764	lysosome
0.40	GO:0098793	presynapse
0.40	GO:0030054	cell junction
0.39	GO:0044446	intracellular organelle part
0.39	GO:0098805	whole membrane
0.39	GO:0098588	bounding membrane of organelle

0.53

GO:0016874

tr|Q6P4U7|Q6P4U7_DANRE
Translocating chain-associated membrane protein
Search

TRAM1

0.91	translocating chain-associated membrane protein 1

0.57	GO:0015031	protein transport
0.35	GO:0090150	establishment of protein localization to membrane
0.34	GO:0046907	intracellular transport
0.34	GO:0072599	establishment of protein localization to endoplasmic reticulum
0.33	GO:0016032	viral process
0.32	GO:0055085	transmembrane transport

0.33	GO:0004872	receptor activity
0.33	GO:0005515	protein binding

0.43	GO:0005783	endoplasmic reticulum
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

tr|Q6P4U8|Q6P4U8_DANRE
Deoxyribonuclease
Search

0.62	Deoxyribonuclease gamma

0.76	GO:0006308	DNA catabolic process
0.54	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.44	GO:0070948	regulation of neutrophil mediated cytotoxicity
0.43	GO:0030262	apoptotic nuclear changes
0.43	GO:0002283	neutrophil activation involved in immune response
0.42	GO:0002673	regulation of acute inflammatory response
0.41	GO:0010623	programmed cell death involved in cell development
0.37	GO:0006898	receptor-mediated endocytosis
0.34	GO:0002088	lens development in camera-type eye
0.34	GO:0060041	retina development in camera-type eye

0.71	GO:0004536	deoxyribonuclease activity
0.56	GO:0004519	endonuclease activity
0.38	GO:0005044	scavenger receptor activity
0.38	GO:0030247	polysaccharide binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0003677	DNA binding

0.40	GO:0005634	nucleus
0.38	GO:0005783	endoplasmic reticulum
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|Q6P4V2|Q6P4V2_DANRE
Amino acid transporter
Search

SLC1A3

0.45	Amino acid transporter

0.58	GO:0140016	D-aspartate import across plasma membrane
0.58	GO:0140009	L-aspartate import across plasma membrane
0.57	GO:0009449	gamma-aminobutyric acid biosynthetic process
0.57	GO:0098712	L-glutamate import across plasma membrane
0.56	GO:0031223	auditory behavior
0.54	GO:0021545	cranial nerve development
0.54	GO:0050885	neuromuscular process controlling balance
0.53	GO:0050806	positive regulation of synaptic transmission
0.52	GO:0007605	sensory perception of sound
0.51	GO:0048667	cell morphogenesis involved in neuron differentiation

0.72	GO:0015293	symporter activity
0.56	GO:0016595	glutamate binding
0.53	GO:0005313	L-glutamate transmembrane transporter activity
0.49	GO:0015081	sodium ion transmembrane transporter activity
0.47	GO:0022853	active ion transmembrane transporter activity
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.52	GO:0043025	neuronal cell body
0.50	GO:0043005	neuron projection
0.49	GO:0009986	cell surface
0.46	GO:0005887	integral component of plasma membrane
0.34	GO:0016323	basolateral plasma membrane
0.34	GO:0098794	postsynapse
0.34	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0019866	organelle inner membrane
0.33	GO:0031966	mitochondrial membrane

tr|Q6P4V3|Q6P4V3_DANRE
Prostaglandin-endoperoxide synthase 2a
Search

PTGS2

0.95	Prostaglandin-endoperoxide synthase 2 (Prostaglandin G/H synthase and cyclooxygenase)

0.86	GO:0019371	cyclooxygenase pathway
0.83	GO:0008217	regulation of blood pressure
0.80	GO:0006954	inflammatory response
0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.58	GO:0071471	cellular response to non-ionic osmotic stress
0.57	GO:0031394	positive regulation of prostaglandin biosynthetic process
0.56	GO:1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
0.56	GO:0031622	positive regulation of fever generation
0.56	GO:0090336	positive regulation of brown fat cell differentiation

0.86	GO:0004666	prostaglandin-endoperoxide synthase activity
0.72	GO:0004601	peroxidase activity
0.63	GO:0020037	heme binding
0.49	GO:0042803	protein homodimerization activity
0.48	GO:0019899	enzyme binding
0.40	GO:0051213	dioxygenase activity
0.36	GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
0.36	GO:0046872	metal ion binding

0.52	GO:0043005	neuron projection
0.49	GO:0005783	endoplasmic reticulum
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0031984	organelle subcompartment
0.38	GO:0097731	9+0 non-motile cilium
0.37	GO:0031090	organelle membrane
0.37	GO:0005901	caveola
0.37	GO:0044441	ciliary part
0.36	GO:0005794	Golgi apparatus
0.34	GO:0043234	protein complex

0.86	EC:1.14.99.1	GO:0004666
0.72	KEGG:R03532	GO:0004601

tr|Q6P4V4|Q6P4V4_DANRE
Catenin, beta like 1
Search

CTNNBL1

0.88	Catenin beta like 1

0.83	GO:0016445	somatic diversification of immunoglobulins
0.74	GO:0043065	positive regulation of apoptotic process
0.46	GO:0006915	apoptotic process
0.43	GO:0008380	RNA splicing
0.42	GO:0006397	mRNA processing
0.34	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0009059	macromolecule biosynthetic process

0.67	GO:0019899	enzyme binding
0.34	GO:0003735	structural constituent of ribosome

0.81	GO:0000974	Prp19 complex
0.75	GO:0005681	spliceosomal complex
0.67	GO:0005654	nucleoplasm
0.34	GO:0005737	cytoplasm
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

tr|Q6P4V6|Q6P4V6_DANRE
DAZ associated protein 2
Search

DAZAP2

0.97	DAZ-associated protein 2

0.37	GO:0006887	exocytosis
0.34	GO:0030036	actin cytoskeleton organization

0.83	GO:0050699	WW domain binding
0.70	GO:0042802	identical protein binding
0.35	GO:0017048	Rho GTPase binding
0.34	GO:0003779	actin binding

0.77	GO:0016607	nuclear speck
0.57	GO:0043234	protein complex
0.40	GO:0005737	cytoplasm
0.37	GO:0099023	tethering complex
0.34	GO:0071944	cell periphery

sp|Q6P5I8|YIPF5_DANRE
Protein YIPF5
Search

0.55	GO:0060628	regulation of ER to Golgi vesicle-mediated transport
0.39	GO:0016192	vesicle-mediated transport
0.38	GO:0015031	protein transport

0.33

GO:0005515

protein binding

0.54	GO:0070971	endoplasmic reticulum exit site
0.51	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.49	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.49	GO:0005794	Golgi apparatus
0.47	GO:0005654	nucleoplasm
0.41	GO:0098827	endoplasmic reticulum subcompartment
0.30	GO:0016021	integral component of membrane

tr|Q6P5J0|Q6P5J0_DANRE
Alpha-amylase
Search

0.42	Alpha-amylase

0.60	GO:0005975	carbohydrate metabolic process
0.38	GO:0071391	cellular response to estrogen stimulus
0.37	GO:0007586	digestion
0.36	GO:1901575	organic substance catabolic process

0.82	GO:0103025	alpha-amylase activity (releasing maltohexaose)
0.81	GO:0004556	alpha-amylase activity
0.53	GO:0043169	cation binding
0.41	GO:0031404	chloride ion binding
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.40	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:3.2.1.1

GO:0004556

tr|Q6P5J5|Q6P5J5_DANRE
Syntaxin 11b, tandem duplicate 1
Search

STX11

0.84	Synaptosomal-associated protein (Fragment)

0.69	GO:0016192	vesicle-mediated transport
0.54	GO:0006886	intracellular protein transport
0.53	GO:0061025	membrane fusion
0.49	GO:0097480	establishment of synaptic vesicle localization
0.49	GO:0099504	synaptic vesicle cycle
0.49	GO:0099643	signal release from synapse
0.49	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.48	GO:0048284	organelle fusion
0.48	GO:0016050	vesicle organization
0.48	GO:0140056	organelle localization by membrane tethering

0.61	GO:0005484	SNAP receptor activity
0.49	GO:0000149	SNARE binding

0.53	GO:0012505	endomembrane system
0.49	GO:0031201	SNARE complex
0.48	GO:0098793	presynapse
0.47	GO:0099503	secretory vesicle
0.44	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q6P5J6|LRC42_DANRE
Leucine-rich repeat-containing protein 42
Search

LRRC42

0.97	Leucine-rich repeat-containing protein 42

0.44

GO:0055114

oxidation-reduction process

0.66

GO:0004800

thyroxine 5'-deiodinase activity

0.66

EC:1.97.1.10

GO:0004800

tr|Q6P5J7|Q6P5J7_DANRE
Chloride intracellular channel 3
Search

0.81	Chloride intracellular channel a

0.76	GO:1902476	chloride transmembrane transport
0.72	GO:0034765	regulation of ion transmembrane transport
0.57	GO:0051726	regulation of cell cycle
0.46	GO:0045669	positive regulation of osteoblast differentiation
0.46	GO:0051881	regulation of mitochondrial membrane potential
0.45	GO:0006749	glutathione metabolic process
0.43	GO:0051284	positive regulation of sequestering of calcium ion
0.43	GO:0050849	negative regulation of calcium-mediated signaling
0.43	GO:0010523	negative regulation of calcium ion transport into cytosol
0.42	GO:0032410	negative regulation of transporter activity

0.76	GO:0005254	chloride channel activity
0.69	GO:0022832	voltage-gated channel activity
0.67	GO:0022839	ion gated channel activity
0.67	GO:0008381	mechanosensitive ion channel activity
0.46	GO:0004364	glutathione transferase activity
0.46	GO:0045296	cadherin binding
0.38	GO:0004602	glutathione peroxidase activity

0.76	GO:0034707	chloride channel complex
0.47	GO:0005737	cytoplasm
0.46	GO:0070062	extracellular exosome
0.44	GO:0005635	nuclear envelope
0.36	GO:0072562	blood microparticle
0.35	GO:0031090	organelle membrane
0.35	GO:0005886	plasma membrane
0.34	GO:0005903	brush border
0.34	GO:0005902	microvillus
0.34	GO:0016363	nuclear matrix

0.46

EC:2.5.1.18

GO:0004364

tr|Q6P5J9|Q6P5J9_DANRE
Snurportin-1
Search

SNUPN

0.93	Snurportin-1 isoform B

0.81	GO:0061015	snRNA import into nucleus
0.76	GO:0006606	protein import into nucleus
0.38	GO:0006370	7-methylguanosine mRNA capping
0.35	GO:0045903	positive regulation of translational fidelity
0.35	GO:0022613	ribonucleoprotein complex biogenesis
0.34	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0071826	ribonucleoprotein complex subunit organization
0.34	GO:0035335	peptidyl-tyrosine dephosphorylation
0.34	GO:0034622	cellular macromolecular complex assembly
0.34	GO:0016072	rRNA metabolic process

0.78	GO:0061608	nuclear import signal receptor activity
0.54	GO:0008565	protein transporter activity
0.48	GO:0003723	RNA binding
0.40	GO:0004484	mRNA guanylyltransferase activity
0.34	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0005515	protein binding

0.56	GO:0005634	nucleus
0.45	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0005846	nuclear cap binding complex
0.35	GO:0012505	endomembrane system
0.35	GO:0030686	90S preribosome
0.34	GO:0043234	protein complex
0.34	GO:0032040	small-subunit processome
0.34	GO:0044446	intracellular organelle part
0.34	GO:0031975	envelope

0.40

EC:2.7.7.50

GO:0004484

tr|Q6P5K1|Q6P5K1_DANRE
ADP-ribosylation factor-like 4a
Search

ARL4A

0.97	ADP ribosylation factor like GTPase 4A

0.56	GO:0050873	brown fat cell differentiation
0.44	GO:0032456	endocytic recycling

0.63	GO:0032550	purine ribonucleoside binding
0.63	GO:0019001	guanyl nucleotide binding
0.52	GO:0032553	ribonucleotide binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0043014	alpha-tubulin binding
0.34	GO:0003924	GTPase activity

0.52	GO:0005730	nucleolus
0.52	GO:0005829	cytosol
0.51	GO:0005654	nucleoplasm
0.45	GO:0005886	plasma membrane

tr|Q6P5K6|Q6P5K6_DANRE
Solute carrier family 25 (Carnitine/acylcarnitine translocase), member 20
Search

SLC25A20

0.80	Carnitine/acylcarnitine translocase

0.51	GO:1902603	carnitine transmembrane transport
0.47	GO:0006839	mitochondrial transport
0.39	GO:1902616	acyl carnitine transmembrane transport
0.35	GO:1902001	fatty acid transmembrane transport
0.35	GO:0032365	intracellular lipid transport
0.34	GO:0015909	long-chain fatty acid transport
0.32	GO:0006518	peptide metabolic process
0.32	GO:0043604	amide biosynthetic process
0.32	GO:0016310	phosphorylation
0.32	GO:0044267	cellular protein metabolic process

0.51	GO:0005476	carnitine:acyl carnitine antiporter activity
0.51	GO:0015226	carnitine transmembrane transporter activity
0.39	GO:0015227	acyl carnitine transmembrane transporter activity
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0016301	kinase activity

0.47	GO:0005829	cytosol
0.46	GO:0031966	mitochondrial membrane
0.46	GO:0019866	organelle inner membrane
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

tr|Q6P5K9|Q6P5K9_DANRE
Zgc:77748
Search

MYADM

0.89	Myeloid-associated differentiation marker

0.51	GO:0090038	negative regulation of protein kinase C signaling
0.51	GO:0034115	negative regulation of heterotypic cell-cell adhesion
0.50	GO:0061028	establishment of endothelial barrier
0.50	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.49	GO:0031579	membrane raft organization
0.48	GO:0072659	protein localization to plasma membrane
0.48	GO:0030837	negative regulation of actin filament polymerization
0.48	GO:0030335	positive regulation of cell migration
0.45	GO:0001933	negative regulation of protein phosphorylation
0.43	GO:0010629	negative regulation of gene expression

0.33	GO:0004697	protein kinase C activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0046872	metal ion binding

0.48	GO:0001726	ruffle
0.48	GO:0030864	cortical actin cytoskeleton
0.47	GO:0045121	membrane raft
0.46	GO:0005911	cell-cell junction
0.39	GO:0005886	plasma membrane
0.35	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.33

EC:2.7.11.13

GO:0004697

tr|Q6P5L0|Q6P5L0_DANRE
ADP-ribosylation factor-like 4D
Search

ARL4D

0.97	ADP-ribosylation factor-like protein 4D

0.36

GO:0009306

protein secretion

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0003924	GTPase activity
0.35	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.41	GO:0031974	membrane-enclosed lumen
0.39	GO:0005886	plasma membrane
0.39	GO:0043228	non-membrane-bounded organelle
0.38	GO:0043227	membrane-bounded organelle
0.38	GO:0044422	organelle part

tr|Q6P5L2|Q6P5L2_DANRE
Diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
Search

DBI

0.62	Diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)

0.44	GO:0036151	phosphatidylcholine acyl-chain remodeling
0.35	GO:0018345	protein palmitoylation
0.35	GO:0050826	response to freezing
0.34	GO:0001666	response to hypoxia
0.34	GO:0035383	thioester metabolic process
0.33	GO:0006869	lipid transport
0.33	GO:0006732	coenzyme metabolic process

0.82	GO:0000062	fatty-acyl-CoA binding
0.39	GO:0046983	protein dimerization activity
0.36	GO:0008289	lipid binding
0.35	GO:0030156	benzodiazepine receptor binding
0.34	GO:0050997	quaternary ammonium group binding
0.34	GO:0070405	ammonium ion binding
0.32	GO:0046872	metal ion binding

0.35	GO:0005794	Golgi apparatus
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0070062	extracellular exosome
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005829	cytosol
0.33	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q6P5L3|RL19_DANRE
60S ribosomal protein L19
Search

RPL19

0.67	Ribosomal protein L19

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.38	GO:0030097	hemopoiesis
0.35	GO:0097421	liver regeneration
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.79	GO:0022625	cytosolic large ribosomal subunit
0.48	GO:0042788	polysomal ribosome
0.36	GO:0005925	focal adhesion
0.33	GO:0019013	viral nucleocapsid
0.30	GO:0016020	membrane

0.32

GO:0016787

tr|Q6P5L5|Q6P5L5_DANRE
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial
Search

NDUFB8

0.94	NADH dehydrogenase 1 beta subcomplex subunit 8, mitochondrial

0.70	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.43	GO:0032981	mitochondrial respiratory chain complex I assembly
0.34	GO:0006626	protein targeting to mitochondrion

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.76	GO:0005747	mitochondrial respiratory chain complex I
0.36	GO:0005783	endoplasmic reticulum
0.34	GO:0005759	mitochondrial matrix
0.30	GO:0016021	integral component of membrane

0.69

GO:0008137

sp|Q6P5L7|ARGLA_DANRE
Arginine and glutamate-rich protein 1-A
Search

ARGLU1

0.97	LOW QUALITY PROTEIN: arginine and glutamate-rich protein 1

0.36	GO:0006351	transcription, DNA-templated
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0048013	ephrin receptor signaling pathway
0.35	GO:0010468	regulation of gene expression
0.32	GO:0055114	oxidation-reduction process

0.77	GO:0045296	cadherin binding
0.35	GO:0046875	ephrin receptor binding
0.34	GO:0004491	methylmalonate-semialdehyde dehydrogenase (acylating) activity
0.32	GO:0046872	metal ion binding

0.67	GO:0005654	nucleoplasm
0.58	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.34

EC:1.2.1.27

GO:0004491

sp|Q6P5L8|HSDL2_DANRE
Hydroxysteroid dehydrogenase-like protein 2
Search

HSDL2

0.90	Hydroxysteroid dehydrogenase protein 2

0.46

GO:0055114

oxidation-reduction process

0.47	GO:0016491	oxidoreductase activity
0.35	GO:0003723	RNA binding

0.72	GO:0042579	microbody
0.55	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.47

GO:0016491

sp|Q6P5M2|WDR61_DANRE
WD repeat-containing protein 61
Search

WDR61

0.92	WD repeat and SOCS box-containing protein 2

0.86	GO:2001162	positive regulation of histone H3-K79 methylation
0.85	GO:0051571	positive regulation of histone H3-K4 methylation
0.85	GO:0080182	histone H3-K4 trimethylation
0.83	GO:0045638	negative regulation of myeloid cell differentiation
0.80	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.45	GO:0016055	Wnt signaling pathway
0.39	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.39	GO:0006351	transcription, DNA-templated
0.37	GO:0016567	protein ubiquitination

0.35

GO:0005515

protein binding

0.85	GO:0055087	Ski complex
0.84	GO:0035327	transcriptionally active chromatin
0.80	GO:0016593	Cdc73/Paf1 complex
0.66	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|Q6P5M3|Q6P5M3_DANRE
Ribosomal protein S9
Search

RPS9

0.45	Ribosomal protein S9 (Predicted)

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.48	GO:0045903	positive regulation of translational fidelity
0.47	GO:0008284	positive regulation of cell proliferation
0.35	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.35	GO:0034660	ncRNA metabolic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.66	GO:0019843	rRNA binding
0.64	GO:0003735	structural constituent of ribosome
0.49	GO:0045182	translation regulator activity
0.36	GO:0000213	tRNA-intron endonuclease activity
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008144	drug binding

0.70	GO:0015935	small ribosomal subunit
0.50	GO:0022626	cytosolic ribosome
0.48	GO:0005730	nucleolus
0.40	GO:0000228	nuclear chromosome
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:3.1.27.9

GO:0000213

tr|Q6P5M5|Q6P5M5_DANRE
Novel protein similar to vertebrate ADP-ribosylation factor 4 (ARF4) (Zgc:77650)
Search

ARF4

0.90	ADP-ribosylation factor 5

0.55	GO:0031584	activation of phospholipase D activity
0.54	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.53	GO:0060996	dendritic spine development
0.53	GO:0045176	apical protein localization
0.53	GO:0061512	protein localization to cilium
0.52	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.51	GO:0006471	protein ADP-ribosylation
0.51	GO:2000377	regulation of reactive oxygen species metabolic process
0.51	GO:0007612	learning
0.49	GO:0043066	negative regulation of apoptotic process

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0005154	epidermal growth factor receptor binding
0.36	GO:0005085	guanyl-nucleotide exchange factor activity
0.35	GO:0017137	Rab GTPase binding
0.34	GO:0003924	GTPase activity

0.52	GO:0032587	ruffle membrane
0.52	GO:0043197	dendritic spine
0.47	GO:0005794	Golgi apparatus
0.45	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0031012	extracellular matrix
0.34	GO:0070382	exocytic vesicle
0.30	GO:0016021	integral component of membrane

tr|Q6P5M7|Q6P5M7_DANRE
ADP-ribosylation factor-like 4Cb
Search

ARL4C

0.97	ADP ribosylation factor like GTPase 4C

0.50	GO:0032456	endocytic recycling
0.44	GO:0050873	brown fat cell differentiation
0.34	GO:0016579	protein deubiquitination
0.33	GO:0006511	ubiquitin-dependent protein catabolic process

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0043014	alpha-tubulin binding
0.34	GO:0003924	GTPase activity
0.34	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.32	GO:0003676	nucleic acid binding

0.48	GO:0005829	cytosol
0.43	GO:0005730	nucleolus
0.42	GO:0005886	plasma membrane
0.42	GO:0005654	nucleoplasm
0.36	GO:0030175	filopodium
0.30	GO:0016021	integral component of membrane

0.34

EC:3.4.19.12

GO:0036459

tr|Q6P5N3|Q6P5N3_DANRE
Krml2.2 protein
Search

MAFB

0.94	V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Bb

0.57	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0021572	rhombomere 6 development
0.55	GO:0021571	rhombomere 5 development
0.54	GO:0021598	abducens nerve morphogenesis
0.53	GO:0045647	negative regulation of erythrocyte differentiation
0.53	GO:0035283	central nervous system segmentation
0.53	GO:0021603	cranial nerve formation

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0008134	transcription factor binding
0.37	GO:0042803	protein homodimerization activity
0.36	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.46	GO:0005667	transcription factor complex
0.33	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm

tr|Q6P603|Q6P603_DANRE
Annexin
Search

0.64

Annexin

0.71	GO:0043086	negative regulation of catalytic activity
0.52	GO:0052362	catabolism by host of symbiont protein
0.52	GO:0044147	negative regulation of development of symbiont involved in interaction with host
0.52	GO:1905597	positive regulation of low-density lipoprotein particle receptor binding
0.52	GO:1905599	positive regulation of low-density lipoprotein receptor activity
0.52	GO:1905581	positive regulation of low-density lipoprotein particle clearance
0.52	GO:1905602	positive regulation of receptor-mediated endocytosis involved in cholesterol transport
0.51	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process
0.51	GO:0036035	osteoclast development
0.51	GO:0052405	negative regulation by host of symbiont molecular function

0.85	GO:0004859	phospholipase inhibitor activity
0.80	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0008092	cytoskeletal protein binding
0.69	GO:0005509	calcium ion binding
0.50	GO:0098641	cadherin binding involved in cell-cell adhesion
0.50	GO:0044548	S100 protein binding
0.49	GO:0048306	calcium-dependent protein binding
0.48	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.48	GO:0002020	protease binding
0.45	GO:0042802	identical protein binding

0.51	GO:1990667	PCSK9-AnxA2 complex
0.48	GO:0005913	cell-cell adherens junction
0.48	GO:0031902	late endosome membrane
0.48	GO:0030496	midbody
0.47	GO:0070062	extracellular exosome
0.47	GO:0005811	lipid droplet
0.47	GO:0005765	lysosomal membrane
0.47	GO:0035749	myelin sheath adaxonal region
0.47	GO:0031012	extracellular matrix
0.47	GO:0098857	membrane microdomain

sp|Q6P606|LYSM4_DANRE
LysM and putative peptidoglycan-binding domain-containing protein 4
Search

LYSMD4

0.82	LysM domain containing 4

0.30

GO:0044425

membrane part

tr|Q6P608|Q6P608_DANRE
Peripheral myelin protein 22a
Search

0.94	Epithelial membrane protein 3

0.49	GO:0016049	cell growth
0.43	GO:0032060	bleb assembly
0.40	GO:0008219	cell death

0.36	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q6P612|Q6P612_DANRE
CCAAT/enhancer binding protein (C/EBP), delta
Search

CEBPD

0.94	CCAAT-enhancer binding protein delta

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0045669	positive regulation of osteoblast differentiation
0.54	GO:0045444	fat cell differentiation
0.51	GO:0048839	inner ear development
0.51	GO:0030097	hemopoiesis
0.50	GO:0006366	transcription by RNA polymerase II
0.49	GO:0051254	positive regulation of RNA metabolic process
0.49	GO:0010557	positive regulation of macromolecule biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.51	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.50	GO:0000987	proximal promoter sequence-specific DNA binding
0.50	GO:0042803	protein homodimerization activity
0.46	GO:0046982	protein heterodimerization activity
0.45	GO:0019900	kinase binding
0.43	GO:0003713	transcription coactivator activity
0.41	GO:0008134	transcription factor binding
0.40	GO:0035035	histone acetyltransferase binding
0.40	GO:0042826	histone deacetylase binding

0.48	GO:0005654	nucleoplasm
0.42	GO:0090575	RNA polymerase II transcription factor complex
0.40	GO:0016363	nuclear matrix
0.39	GO:0000779	condensed chromosome, centromeric region
0.38	GO:0000790	nuclear chromatin
0.35	GO:0005730	nucleolus
0.34	GO:0005737	cytoplasm

tr|Q6P694|Q6P694_DANRE
Non imprinted in Prader-Willi/Angelman syndrome 2 (Human)
Search

NIPA2

0.91	Non-imprinted in Prader-Willi/Angelman syndrome region protein 2

0.77

GO:1903830

magnesium ion transmembrane transport

0.78	GO:0015095	magnesium ion transmembrane transporter activity
0.33	GO:0005515	protein binding

0.50	GO:0005769	early endosome
0.40	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q6P696|Q6P696_DANRE
Lactoylglutathione lyase
Search

GLO1

0.49	Lactoylglutathione lyase

0.54	GO:0030316	osteoclast differentiation
0.51	GO:0043066	negative regulation of apoptotic process
0.47	GO:0006357	regulation of transcription by RNA polymerase II
0.38	GO:0009438	methylglyoxal metabolic process
0.38	GO:0006749	glutathione metabolic process
0.35	GO:0005975	carbohydrate metabolic process
0.34	GO:0042182	ketone catabolic process
0.34	GO:0046185	aldehyde catabolic process
0.34	GO:0006089	lactate metabolic process
0.33	GO:0006090	pyruvate metabolic process

0.80	GO:0004462	lactoylglutathione lyase activity
0.54	GO:0046872	metal ion binding

0.47	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.41	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome

0.80	EC:4.4.1.5	GO:0004462
0.80	KEGG:R02530	GO:0004462

tr|Q6P697|Q6P697_DANRE
Transgelin
Search

TAGLN3

0.82	Transgelin

0.50	GO:0000122	negative regulation of transcription by RNA polymerase II
0.39	GO:0048856	anatomical structure development
0.39	GO:0048869	cellular developmental process
0.36	GO:0030036	actin cytoskeleton organization
0.33	GO:0006508	proteolysis
0.33	GO:0032501	multicellular organismal process

0.74	GO:0051015	actin filament binding
0.36	GO:0045296	cadherin binding
0.34	GO:0004252	serine-type endopeptidase activity

0.52	GO:0043209	myelin sheath
0.43	GO:0005634	nucleus
0.36	GO:0015629	actin cytoskeleton
0.34	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.34

GO:0004252

sp|Q6P698|PLSL_DANRE
Plastin-2
Search

LCP1

0.94	Lymphocyte cytosolic plastin 1

0.55	GO:0071803	positive regulation of podosome assembly
0.55	GO:0010737	protein kinase A signaling
0.54	GO:0051017	actin filament bundle assembly
0.54	GO:0022617	extracellular matrix disassembly
0.54	GO:0002286	T cell activation involved in immune response
0.52	GO:0033157	regulation of intracellular protein transport
0.50	GO:0016477	cell migration
0.49	GO:0051639	actin filament network formation
0.48	GO:0051764	actin crosslink formation
0.41	GO:0048513	animal organ development

0.74	GO:0003779	actin binding
0.69	GO:0005509	calcium ion binding
0.53	GO:0005178	integrin binding
0.48	GO:0051020	GTPase binding
0.48	GO:0042802	identical protein binding
0.35	GO:0004181	metallocarboxypeptidase activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0004386	helicase activity
0.32	GO:0016887	ATPase activity
0.32	GO:0030554	adenyl nucleotide binding

0.55	GO:0032432	actin filament bundle
0.54	GO:0005884	actin filament
0.54	GO:0002102	podosome
0.54	GO:0001891	phagocytic cup
0.53	GO:0042641	actomyosin
0.53	GO:0001726	ruffle
0.53	GO:0030175	filopodium
0.51	GO:0005925	focal adhesion
0.50	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005829	cytosol

0.35

EC:3.4.17

GO:0004181

tr|Q6P6E0|Q6P6E0_DANRE
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g
Search

ATP5L

0.89	ATP synthase subunit gserine-threonine

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.45	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.36	GO:0051568	histone H3-K4 methylation
0.35	GO:0042407	cristae formation
0.34	GO:0006839	mitochondrial transport
0.34	GO:0006511	ubiquitin-dependent protein catabolic process
0.34	GO:0016567	protein ubiquitination
0.33	GO:0046907	intracellular transport
0.33	GO:0021691	cerebellar Purkinje cell layer maturation

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.46	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.45	GO:0019829	cation-transporting ATPase activity
0.36	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.36	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.36	GO:0047624	adenosine-tetraphosphatase activity
0.34	GO:0034450	ubiquitin-ubiquitin ligase activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0003677	DNA binding

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.36	GO:0070062	extracellular exosome
0.36	GO:0071339	MLL1 complex
0.34	GO:0000151	ubiquitin ligase complex
0.33	GO:0030126	COPI vesicle coat
0.32	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.36

EC:3.6.1.14

GO:0047624

tr|Q6P6E4|Q6P6E4_DANRE
LSM4 homolog, U6 small nuclear RNA and mRNA degradation-associated
Search

LSM4

0.91	LSM4 homolog, U6 small nuclear RNA and mRNA degradation-associated

0.78	GO:0000956	nuclear-transcribed mRNA catabolic process
0.75	GO:0000398	mRNA splicing, via spliceosome
0.47	GO:0033962	cytoplasmic mRNA processing body assembly
0.33	GO:0050794	regulation of cellular process
0.33	GO:0023052	signaling
0.33	GO:0007154	cell communication
0.32	GO:0051716	cellular response to stimulus
0.32	GO:0010556	regulation of macromolecule biosynthetic process
0.32	GO:0080090	regulation of primary metabolic process
0.32	GO:0051171	regulation of nitrogen compound metabolic process

0.53	GO:0042731	PH domain binding
0.46	GO:0017070	U6 snRNA binding
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003677	DNA binding

0.57	GO:0030529	intracellular ribonucleoprotein complex
0.44	GO:0005829	cytosol
0.44	GO:0120114	Sm-like protein family complex
0.41	GO:0019013	viral nucleocapsid
0.41	GO:0043234	protein complex
0.41	GO:0044428	nuclear part
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0043005	neuron projection
0.34	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

tr|Q6P6E5|Q6P6E5_DANRE
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7
Search

NDUFB7

0.91	NADH dehydrogenase ubiquinone 1 beta subcomplex subunit 7

0.53	GO:0055114	oxidation-reduction process
0.51	GO:0032981	mitochondrial respiratory chain complex I assembly
0.33	GO:0006119	oxidative phosphorylation

0.69	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005739	mitochondrion
0.50	GO:0045271	respiratory chain complex I
0.49	GO:0031970	organelle envelope lumen
0.45	GO:1990204	oxidoreductase complex
0.42	GO:0019866	organelle inner membrane

0.69

GO:0008137

sp|Q6P6E6|CSN9_DANRE
COP9 signalosome complex subunit 9
Search

0.97	Myeloma overexpressed gene 2 protein homolog

0.79	GO:0034644	cellular response to UV
0.75	GO:0008284	positive regulation of cell proliferation
0.64	GO:2000435	negative regulation of protein neddylation
0.61	GO:0051220	cytoplasmic sequestering of protein
0.41	GO:0060326	cell chemotaxis
0.39	GO:0006955	immune response

0.42	GO:0005515	protein binding
0.42	GO:0031409	pigment binding
0.39	GO:0030545	receptor regulator activity
0.38	GO:0003723	RNA binding

0.76	GO:0008180	COP9 signalosome
0.71	GO:0000790	nuclear chromatin
0.66	GO:0005654	nucleoplasm
0.47	GO:0005737	cytoplasm
0.38	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|Q6P6E8|Q6P6E8_DANRE
ADP-ribosylation factor-like 5C
Search

0.91	ADP ribosylation factor like GTPase 5C

0.54

GO:1903292

protein localization to Golgi membrane

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003779	actin binding

0.45	GO:0005622	intracellular
0.30	GO:0016020	membrane

tr|Q6P6F0|Q6P6F0_DANRE
Ribosomal protein S17
Search

RPS17

0.72	Ribosomal protein S17

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.50	GO:0000028	ribosomal small subunit assembly
0.47	GO:0034101	erythrocyte homeostasis
0.42	GO:0016072	rRNA metabolic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0003730	mRNA 3'-UTR binding
0.34	GO:0045182	translation regulator activity
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.49	GO:0044445	cytosolic part
0.42	GO:0044446	intracellular organelle part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle

0.32

GO:0016787

tr|Q6P6X6|Q6P6X6_DANRE
NOP58 ribonucleoprotein homolog (yeast)
Search

NOP58

0.81	Nucleolar protein 5

0.78	GO:0048254	snoRNA localization
0.54	GO:0000154	rRNA modification
0.38	GO:0016049	cell growth

0.76	GO:0001094	TFIID-class transcription factor binding
0.73	GO:0030515	snoRNA binding
0.73	GO:0051117	ATPase binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.77	GO:0070761	pre-snoRNP complex
0.73	GO:0015030	Cajal body
0.71	GO:0005732	small nucleolar ribonucleoprotein complex
0.71	GO:0001650	fibrillar center
0.59	GO:0005829	cytosol
0.58	GO:0032040	small-subunit processome
0.51	GO:0019013	viral nucleocapsid
0.30	GO:0031224	intrinsic component of membrane

sp|Q6P6X9|NUP53_DANRE
Nucleoporin NUP53
Search

NUP35

0.90	Nucleoporin 35

0.74	GO:0051028	mRNA transport
0.68	GO:0006913	nucleocytoplasmic transport
0.57	GO:0015031	protein transport
0.47	GO:0006999	nuclear pore organization
0.45	GO:0034504	protein localization to nucleus
0.43	GO:0072594	establishment of protein localization to organelle
0.38	GO:2001141	regulation of RNA biosynthetic process
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression
0.37	GO:1990823	response to leukemia inhibitory factor

0.50	GO:0003676	nucleic acid binding
0.45	GO:0005487	structural constituent of nuclear pore
0.43	GO:0005543	phospholipid binding
0.36	GO:0042803	protein homodimerization activity

0.75	GO:0031965	nuclear membrane
0.75	GO:0005643	nuclear pore
0.47	GO:0005654	nucleoplasm
0.41	GO:0005886	plasma membrane
0.37	GO:0005652	nuclear lamina
0.34	GO:0005668	RNA polymerase transcription factor SL1 complex
0.33	GO:0044216	other organism cell
0.33	GO:0018995	host
0.30	GO:0016021	integral component of membrane

sp|Q6P6Y1|K1468_DANRE
LisH domain and HEAT repeat-containing protein KIAA1468 homolog
Search

KIAA1468

0.91	LisH domain and HEAT repeat-containing protein KIAA1468

0.30

GO:0044425

membrane part

tr|Q6P6Y4|Q6P6Y4_DANRE
RAB guanine nucleotide exchange factor (GEF) 1
Search

RABGEF1

0.93	RAB guanine nucleotide exchange factor (GEF) 1

0.41	GO:1900234	regulation of Kit signaling pathway
0.40	GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway
0.40	GO:0043305	negative regulation of mast cell degranulation
0.40	GO:1900165	negative regulation of interleukin-6 secretion
0.40	GO:0048261	negative regulation of receptor-mediated endocytosis
0.39	GO:0002686	negative regulation of leukocyte migration
0.39	GO:0050728	negative regulation of inflammatory response
0.39	GO:0046580	negative regulation of Ras protein signal transduction
0.38	GO:0006612	protein targeting to membrane
0.37	GO:0001933	negative regulation of protein phosphorylation

0.61	GO:0008270	zinc ion binding
0.53	GO:0003677	DNA binding
0.39	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.38	GO:0061630	ubiquitin protein ligase activity

0.40	GO:0005769	early endosome
0.38	GO:0005730	nucleolus
0.37	GO:0005829	cytosol
0.37	GO:0055037	recycling endosome
0.32	GO:0010008	endosome membrane
0.30	GO:0016021	integral component of membrane

sp|Q6P7E4|PDLI7_DANRE
PDZ and LIM domain protein 7
Search

PDLIM7

0.89	PDZ and LIM domain protein 7

0.41	GO:0003294	atrial ventricular junction remodeling
0.40	GO:0043433	negative regulation of DNA binding transcription factor activity
0.40	GO:0003190	atrioventricular valve formation
0.40	GO:0033339	pectoral fin development
0.40	GO:0001503	ossification
0.40	GO:0030036	actin cytoskeleton organization
0.39	GO:0001947	heart looping
0.39	GO:0001756	somitogenesis
0.39	GO:0032880	regulation of protein localization
0.38	GO:0006913	nucleocytoplasmic transport

0.54	GO:0046872	metal ion binding
0.41	GO:0033613	activating transcription factor binding

0.46	GO:0097517	contractile actin filament bundle
0.46	GO:0042641	actomyosin
0.44	GO:0031941	filamentous actin
0.42	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0005913	cell-cell adherens junction
0.42	GO:0001726	ruffle
0.41	GO:0005925	focal adhesion
0.40	GO:0030864	cortical actin cytoskeleton
0.38	GO:0030018	Z disc
0.37	GO:0005634	nucleus

tr|Q6P7X5|Q6P7X5_DANRE
Potassium channel tetramerisation domain containing 10
Search

KCTD10

0.89	Potassium channel tetramerization domain

0.78	GO:0051260	protein homooligomerization
0.60	GO:0006511	ubiquitin-dependent protein catabolic process
0.58	GO:1900125	regulation of hyaluronan biosynthetic process
0.57	GO:0036302	atrioventricular canal development
0.57	GO:0003157	endocardium development
0.57	GO:0033339	pectoral fin development
0.55	GO:0002040	sprouting angiogenesis
0.55	GO:0001947	heart looping
0.54	GO:0043433	negative regulation of DNA binding transcription factor activity
0.51	GO:0000122	negative regulation of transcription by RNA polymerase II

0.68	GO:0005112	Notch binding
0.61	GO:0098811	transcriptional repressor activity, RNA polymerase II activating transcription factor binding
0.41	GO:0017049	GTP-Rho binding
0.38	GO:0042802	identical protein binding
0.38	GO:0004842	ubiquitin-protein transferase activity

0.58	GO:0005654	nucleoplasm
0.56	GO:0005829	cytosol
0.40	GO:0031463	Cul3-RING ubiquitin ligase complex

0.38

GO:0004842

tr|Q6P7Y0|Q6P7Y0_DANRE
Ubiquitin-conjugating enzyme E2, J1
Search

UBE2J1

0.92	Ubiquitin-conjugating enzyme E2 J1 isoform A

0.56	GO:1904153	negative regulation of retrograde protein transport, ER to cytosol
0.56	GO:0042534	regulation of tumor necrosis factor biosynthetic process
0.54	GO:0018279	protein N-linked glycosylation via asparagine
0.53	GO:0007286	spermatid development
0.53	GO:0030433	ubiquitin-dependent ERAD pathway
0.50	GO:0016567	protein ubiquitination

0.55	GO:0061631	ubiquitin conjugating enzyme activity
0.53	GO:0031625	ubiquitin protein ligase binding
0.44	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005737	cytoplasm
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment
0.33	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

sp|Q6P7Y3|PR38B_DANRE
Pre-mRNA-splicing factor 38B
Search

PRPF38B

0.82	Pre-mRNA processing factor 38B

0.54	GO:0008380	RNA splicing
0.52	GO:0006397	mRNA processing

0.40

GO:0003723

RNA binding

0.85

GO:0071011

precatalytic spliceosome

tr|Q6P937|Q6P937_DANRE
Clathrin light chain
Search

CLTA

0.67	Clathrin light chain A

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.50	GO:0048268	clathrin coat assembly
0.44	GO:0098657	import into cell
0.36	GO:0051301	cell division
0.36	GO:0007049	cell cycle
0.36	GO:0032802	low-density lipoprotein particle receptor catabolic process
0.35	GO:0034383	low-density lipoprotein particle clearance
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.34	GO:0007018	microtubule-based movement

0.62	GO:0005198	structural molecule activity
0.57	GO:0032050	clathrin heavy chain binding
0.37	GO:0042277	peptide binding
0.37	GO:0032403	protein complex binding
0.37	GO:0051020	GTPase binding

0.83	GO:0030130	clathrin coat of trans-Golgi network vesicle
0.82	GO:0030132	clathrin coat of coated pit
0.51	GO:0071439	clathrin complex
0.39	GO:0099631	postsynaptic endocytic zone cytoplasmic component
0.38	GO:0030672	synaptic vesicle membrane
0.38	GO:0005819	spindle
0.37	GO:0045334	clathrin-coated endocytic vesicle
0.36	GO:0005802	trans-Golgi network
0.36	GO:0036020	endolysosome membrane
0.35	GO:0030666	endocytic vesicle membrane

tr|Q6P943|Q6P943_DANRE
Signal transducer and activator of transcription
Search

0.72	Signal transducer and activator of transcription

0.60	GO:0007165	signal transduction
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0071346	cellular response to interferon-gamma
0.55	GO:0001937	negative regulation of endothelial cell proliferation
0.55	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.55	GO:0046725	negative regulation by virus of viral protein levels in host cell
0.54	GO:0071357	cellular response to type I interferon

0.64	GO:0004871	signal transducer activity
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.52	GO:0035035	histone acetyltransferase binding
0.51	GO:1990841	promoter-specific chromatin binding
0.51	GO:0070491	repressing transcription factor binding
0.50	GO:0035257	nuclear hormone receptor binding
0.50	GO:0005164	tumor necrosis factor receptor binding
0.49	GO:0045296	cadherin binding
0.49	GO:0042393	histone binding

0.61	GO:0005634	nucleus
0.48	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0070013	intracellular organelle lumen
0.46	GO:0000785	chromatin
0.44	GO:0005829	cytosol
0.41	GO:0043234	protein complex
0.39	GO:0030425	dendrite
0.39	GO:0030424	axon

sp|Q6P949|PHF2_DANRE
Lysine-specific demethylase phf2
Search

PHF2

0.93	PHD finger protein 2

0.68	GO:0061188	negative regulation of chromatin silencing at rDNA
0.67	GO:0033169	histone H3-K9 demethylation
0.37	GO:0035574	histone H4-K20 demethylation
0.37	GO:0070544	histone H3-K36 demethylation
0.37	GO:0071557	histone H3-K27 demethylation
0.36	GO:0045943	positive regulation of transcription by RNA polymerase I
0.36	GO:0000082	G1/S transition of mitotic cell cycle
0.33	GO:0060319	primitive erythrocyte differentiation
0.33	GO:0048703	embryonic viscerocranium morphogenesis
0.33	GO:0043523	regulation of neuron apoptotic process

0.67	GO:0032454	histone demethylase activity (H3-K9 specific)
0.64	GO:0035064	methylated histone binding
0.60	GO:0003713	transcription coactivator activity
0.54	GO:0046872	metal ion binding
0.37	GO:0035575	histone demethylase activity (H4-K20 specific)
0.37	GO:0051864	histone demethylase activity (H3-K36 specific)
0.37	GO:0071558	histone demethylase activity (H3-K27 specific)
0.36	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.60	GO:0000776	kinetochore
0.53	GO:0031974	membrane-enclosed lumen
0.34	GO:0012505	endomembrane system
0.34	GO:0031967	organelle envelope
0.34	GO:0031090	organelle membrane

0.37

EC:1.14.11.27

GO:0051864

sp|Q6P950|PR3CB_DANRE
Protein phosphatase 1 regulatory subunit 3C-B
Search

PPP1R3C

0.86	Protein phosphatase 1 regulatory subunit

0.74	GO:0043666	regulation of phosphoprotein phosphatase activity
0.67	GO:0005977	glycogen metabolic process
0.51	GO:0009250	glucan biosynthetic process
0.47	GO:0005981	regulation of glycogen catabolic process
0.35	GO:0006470	protein dephosphorylation
0.35	GO:0005979	regulation of glycogen biosynthetic process
0.34	GO:0071456	cellular response to hypoxia
0.34	GO:0006605	protein targeting

0.75	GO:0019888	protein phosphatase regulator activity
0.55	GO:0019903	protein phosphatase binding
0.35	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0016746	transferase activity, transferring acyl groups

0.45	GO:0000164	protein phosphatase type 1 complex
0.35	GO:0042587	glycogen granule
0.33	GO:0005829	cytosol
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.35

EC:3.1.3.16

GO:0004721

tr|Q6P951|Q6P951_DANRE
6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3
Search

PFKFB3

0.97	6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3 splice variant 3

0.83	GO:0006003	fructose 2,6-bisphosphate metabolic process
0.83	GO:0006000	fructose metabolic process
0.74	GO:0046835	carbohydrate phosphorylation
0.37	GO:0016311	dephosphorylation
0.36	GO:0007420	brain development
0.36	GO:0006110	regulation of glycolytic process
0.35	GO:0051197	positive regulation of coenzyme metabolic process
0.35	GO:1903580	positive regulation of ATP metabolic process
0.34	GO:0019083	viral transcription
0.34	GO:0045913	positive regulation of carbohydrate metabolic process

0.84	GO:0003873	6-phosphofructo-2-kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity
0.34	GO:0003968	RNA-directed 5'-3' RNA polymerase activity

0.47	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol

0.84	EC:2.7.1.105	GO:0003873
0.84	KEGG:R02732	GO:0003873

tr|Q6P957|Q6P957_DANRE
Stannin
Search

SNN

0.78

Stannin

0.34

GO:0009636

response to toxic substance

0.44	GO:0046872	metal ion binding
0.33	GO:0003677	DNA binding

0.41	GO:0005737	cytoplasm
0.39	GO:0031968	organelle outer membrane
0.35	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0044425	membrane part

sp|Q6P963|GLO2_DANRE
Hydroxyacylglutathione hydrolase, mitochondrial
Search

HAGH

0.47	Mitochondrial hydroxyacylglutathione hydrolase

0.78	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
0.51	GO:0006750	glutathione biosynthetic process
0.35	GO:0019853	L-ascorbic acid biosynthetic process
0.35	GO:0007283	spermatogenesis
0.34	GO:0006090	pyruvate metabolic process

0.78	GO:0004416	hydroxyacylglutathione hydrolase activity
0.36	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.42	GO:0005759	mitochondrial matrix
0.36	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol

0.78

EC:3.1.2.6

GO:0004416

sp|Q6P964|P4R2A_DANRE
Serine/threonine-protein phosphatase 4 regulatory subunit 2-A
Search

PPP4R2

0.93	Serine/threonine-protein phosphatase 4 regulatory subunit 2-A

0.79	GO:0043666	regulation of phosphoprotein phosphatase activity
0.53	GO:0010569	regulation of double-strand break repair via homologous recombination
0.37	GO:0002244	hematopoietic progenitor cell differentiation
0.36	GO:0008380	RNA splicing
0.35	GO:0006397	mRNA processing
0.33	GO:0006464	cellular protein modification process

0.80	GO:0019888	protein phosphatase regulator activity
0.50	GO:0030674	protein binding, bridging
0.34	GO:0016757	transferase activity, transferring glycosyl groups

0.85	GO:0030289	protein phosphatase 4 complex
0.46	GO:0005654	nucleoplasm
0.36	GO:0005815	microtubule organizing center
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016757

tr|Q6P967|Q6P967_DANRE
Guanine nucleotide-binding protein (G protein), alpha-activating activity polypeptide O, b
Search

GNAO1

0.77	Guanine nucleotide binding protein alpha O

0.82	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.52	GO:0007212	dopamine receptor signaling pathway
0.49	GO:0008016	regulation of heart contraction
0.48	GO:0007626	locomotory behavior
0.39	GO:0007417	central nervous system development
0.39	GO:0030182	neuron differentiation
0.38	GO:0120036	plasma membrane bounded cell projection organization
0.38	GO:0035567	non-canonical Wnt signaling pathway
0.38	GO:0048468	cell development
0.38	GO:0043278	response to morphine

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0031821	G-protein coupled serotonin receptor binding
0.48	GO:0031852	mu-type opioid receptor binding
0.48	GO:0051430	corticotropin-releasing hormone receptor 1 binding

0.49	GO:0043209	myelin sheath
0.48	GO:0030425	dendrite
0.48	GO:0044297	cell body
0.46	GO:1905360	GTPase complex
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.41	GO:0098797	plasma membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

tr|Q6P969|Q6P969_DANRE
Elongation factor 1-alpha
Search

0.45	Translation elongation factor EF-1 subunit alpha

0.70	GO:0006414	translational elongation
0.51	GO:0071364	cellular response to epidermal growth factor stimulus
0.35	GO:0010942	positive regulation of cell death
0.35	GO:1904714	regulation of chaperone-mediated autophagy
0.35	GO:1903427	negative regulation of reactive oxygen species biosynthetic process
0.35	GO:1990090	cellular response to nerve growth factor stimulus
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0090218	positive regulation of lipid kinase activity
0.34	GO:0010976	positive regulation of neuron projection development
0.34	GO:0035690	cellular response to drug

0.70	GO:0003746	translation elongation factor activity
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0019901	protein kinase binding
0.46	GO:0005516	calmodulin binding
0.43	GO:0000049	tRNA binding
0.34	GO:0003729	mRNA binding

0.48	GO:0032587	ruffle membrane
0.48	GO:0005737	cytoplasm
0.47	GO:0043209	myelin sheath
0.46	GO:0005730	nucleolus
0.45	GO:0015629	actin cytoskeleton
0.43	GO:0044430	cytoskeletal part
0.37	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0097708	intracellular vesicle

tr|Q6P971|Q6P971_DANRE
Pyrroline-5-carboxylate reductase
Search

0.53	Pyrroline-5-carboxylate reductase

0.75	GO:0006561	proline biosynthetic process
0.58	GO:0017144	drug metabolic process
0.52	GO:0055114	oxidation-reduction process
0.48	GO:1901032	negative regulation of response to reactive oxygen species
0.48	GO:2001039	negative regulation of cellular response to drug
0.48	GO:1903205	regulation of hydrogen peroxide-induced cell death
0.48	GO:1903202	negative regulation of oxidative stress-induced cell death
0.47	GO:0051881	regulation of mitochondrial membrane potential
0.45	GO:0034599	cellular response to oxidative stress
0.41	GO:0007420	brain development

0.78	GO:0004735	pyrroline-5-carboxylate reductase activity
0.44	GO:0042802	identical protein binding
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003677	DNA binding

0.40	GO:0005739	mitochondrion
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0005634	nucleus
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:1.5.1.2

GO:0004735

tr|Q6P972|Q6P972_DANRE
Tubulin alpha chain
Search

0.53	Tubulin alpha chain

0.71	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.44	GO:0071353	cellular response to interleukin-4
0.36	GO:0030705	cytoskeleton-dependent intracellular transport
0.35	GO:0021634	optic nerve formation
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0021782	glial cell development
0.34	GO:0042552	myelination
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0031625	ubiquitin protein ligase binding
0.42	GO:0003725	double-stranded RNA binding
0.36	GO:0019904	protein domain specific binding
0.34	GO:0019901	protein kinase binding
0.34	GO:0046982	protein heterodimerization activity

0.73	GO:0005874	microtubule
0.48	GO:0043209	myelin sheath
0.48	GO:0005737	cytoplasm
0.43	GO:0035770	ribonucleoprotein granule
0.42	GO:0031982	vesicle
0.40	GO:0012505	endomembrane system
0.40	GO:0045121	membrane raft
0.38	GO:0043230	extracellular organelle
0.37	GO:0005615	extracellular space
0.34	GO:0030496	midbody

tr|Q6P976|Q6P976_DANRE
Neurensin 1
Search

NRSN1

0.97	Vesicular membrane protein of 24 kDa

0.74

GO:0007399

nervous system development

0.33

GO:0005515

protein binding

0.77	GO:0030133	transport vesicle
0.56	GO:0030426	growth cone
0.54	GO:0043025	neuronal cell body
0.32	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q6P977|Q6P977_DANRE
RAB42, member RAS oncogene family a
Search

0.95	RAB42, member RAS oncogene family a

0.52	GO:0090383	phagosome acidification
0.52	GO:0090385	phagosome-lysosome fusion
0.46	GO:0010506	regulation of autophagy
0.45	GO:0050808	synapse organization
0.38	GO:0006914	autophagy
0.36	GO:0015031	protein transport

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0031489	myosin V binding
0.33	GO:0004767	sphingomyelin phosphodiesterase activity

0.51	GO:0031982	vesicle
0.51	GO:0005794	Golgi apparatus
0.47	GO:0043005	neuron projection
0.35	GO:0031090	organelle membrane
0.35	GO:0005764	lysosome
0.35	GO:0044446	intracellular organelle part
0.34	GO:0098805	whole membrane
0.34	GO:0005886	plasma membrane
0.33	GO:0005829	cytosol
0.32	GO:0005634	nucleus

0.33	EC:3.1.4.12	GO:0004767
0.33	KEGG:R02541	GO:0004767

tr|Q6P978|Q6P978_DANRE
Elongation of very long chain fatty acids protein 4
Search

ELOVL4

0.55	Elongation of very long chain fatty acids protein 4

0.76	GO:0019367	fatty acid elongation, saturated fatty acid
0.75	GO:0042761	very long-chain fatty acid biosynthetic process
0.74	GO:0034626	fatty acid elongation, polyunsaturated fatty acid
0.73	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.70	GO:0006636	unsaturated fatty acid biosynthetic process
0.49	GO:0034625	fatty acid elongation, monounsaturated fatty acid
0.47	GO:0030148	sphingolipid biosynthetic process
0.34	GO:0009584	detection of visible light

0.82	GO:0102756	very-long-chain 3-ketoacyl-CoA synthase activity
0.82	GO:0102338	3-oxo-lignoceronyl-CoA synthase activity
0.82	GO:0102336	3-oxo-arachidoyl-CoA synthase activity
0.82	GO:0102337	3-oxo-cerotoyl-CoA synthase activity
0.74	GO:0009922	fatty acid elongase activity
0.35	GO:0008020	G-protein coupled photoreceptor activity
0.33	GO:0005515	protein binding

0.63	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.82

EC:2.3.1.199

GO:0102338

tr|Q6P980|Q6P980_DANRE
Superoxide dismutase
Search

SOD2

0.47	Superoxide dismutase

0.76	GO:0071450	cellular response to oxygen radical
0.76	GO:0000303	response to superoxide
0.75	GO:0006801	superoxide metabolic process
0.69	GO:0098869	cellular oxidant detoxification
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0001306	age-dependent response to oxidative stress
0.48	GO:0003070	regulation of systemic arterial blood pressure by neurotransmitter
0.47	GO:0048773	erythrophore differentiation
0.47	GO:0051597	response to methylmercury
0.47	GO:0001780	neutrophil homeostasis

0.77	GO:0004784	superoxide dismutase activity
0.54	GO:0046872	metal ion binding
0.37	GO:0042802	identical protein binding
0.37	GO:0019825	oxygen binding
0.36	GO:0019899	enzyme binding
0.33	GO:0003677	DNA binding

0.43	GO:0043209	myelin sheath
0.42	GO:0005759	mitochondrial matrix
0.38	GO:0031966	mitochondrial membrane
0.38	GO:0019866	organelle inner membrane
0.36	GO:0009295	nucleoid
0.36	GO:0070062	extracellular exosome
0.34	GO:0043232	intracellular non-membrane-bounded organelle

0.77

EC:1.15.1.1

GO:0004784

tr|Q6P9Z2|Q6P9Z2_DANRE
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
Search

DDX23

0.80	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23

0.49	GO:0010501	RNA secondary structure unwinding
0.46	GO:0000375	RNA splicing, via transesterification reactions
0.35	GO:1901385	regulation of voltage-gated calcium channel activity
0.35	GO:0006397	mRNA processing
0.35	GO:0007528	neuromuscular junction development
0.35	GO:0007264	small GTPase mediated signal transduction
0.35	GO:0007268	chemical synaptic transmission
0.35	GO:0070588	calcium ion transmembrane transport
0.34	GO:0022618	ribonucleoprotein complex assembly

0.61	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.46	GO:0008186	RNA-dependent ATPase activity
0.41	GO:0140098	catalytic activity, acting on RNA
0.36	GO:0008331	high voltage-gated calcium channel activity
0.34	GO:0003924	GTPase activity
0.34	GO:0061505	DNA topoisomerase II activity

0.58	GO:0005682	U5 snRNP
0.56	GO:0071013	catalytic step 2 spliceosome
0.52	GO:0005730	nucleolus
0.38	GO:0070062	extracellular exosome
0.37	GO:0005737	cytoplasm
0.35	GO:0005891	voltage-gated calcium channel complex
0.35	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.34	GO:0005654	nucleoplasm

sp|Q6P9Z4|FEM1A_DANRE
Protein fem-1 homolog A
Search

FEM1C

0.96	Fem-1 homolog a (C. elegans)

0.48	GO:0050728	negative regulation of inflammatory response
0.46	GO:0016567	protein ubiquitination
0.40	GO:0043687	post-translational protein modification
0.36	GO:0051438	regulation of ubiquitin-protein transferase activity

0.52	GO:0031867	EP4 subtype prostaglandin E2 receptor binding
0.35	GO:0004842	ubiquitin-protein transferase activity

0.67	GO:0005654	nucleoplasm
0.66	GO:0005829	cytosol

0.35

GO:0004842

sp|Q6PBA2|LS12A_DANRE
Protein LSM12 homolog A
Search

0.45	GO:0070932	histone H3 deacetylation
0.44	GO:0040029	regulation of gene expression, epigenetic
0.41	GO:0006749	glutathione metabolic process
0.38	GO:0006351	transcription, DNA-templated
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.45	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
0.41	GO:0004364	glutathione transferase activity

0.39	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.45

GO:0032041

tr|Q6PBA3|Q6PBA3_DANRE
Transporter
Search

SLC6A19

0.47	Transporter

0.76	GO:0006836	neurotransmitter transport
0.55	GO:0055085	transmembrane transport
0.52	GO:0015804	neutral amino acid transport
0.39	GO:0007584	response to nutrient
0.36	GO:0015803	branched-chain amino acid transport
0.34	GO:0006812	cation transport

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.52	GO:0015175	neutral amino acid transmembrane transporter activity
0.38	GO:0070728	leucine binding
0.34	GO:0005283	sodium:amino acid symporter activity
0.33	GO:0005515	protein binding

0.59	GO:0005887	integral component of plasma membrane
0.53	GO:0031526	brush border membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005737	cytoplasm

sp|Q6PBA8|MNS1_DANRE
Meiosis-specific nuclear structural protein 1
Search

MNS1

0.97	LOW QUALITY PROTEIN: meiosis-specific nuclear structural protein 1

0.78	GO:0070986	left/right axis specification
0.78	GO:0045724	positive regulation of cilium assembly
0.77	GO:0044782	cilium organization
0.70	GO:0007283	spermatogenesis
0.50	GO:0051321	meiotic cell cycle
0.36	GO:0006004	fucose metabolic process
0.34	GO:0032259	methylation
0.33	GO:0042023	DNA endoreduplication
0.33	GO:0010332	response to gamma radiation
0.33	GO:0035264	multicellular organism growth

0.67	GO:0042802	identical protein binding
0.35	GO:0016757	transferase activity, transferring glycosyl groups
0.34	GO:0008168	methyltransferase activity

0.78	GO:0031514	motile cilium
0.73	GO:0097223	sperm part
0.72	GO:0005930	axoneme
0.69	GO:0005882	intermediate filament
0.67	GO:0005635	nuclear envelope
0.33	GO:0033186	CAF-1 complex

0.35

GO:0016757

tr|Q6PBH4|Q6PBH4_DANRE
Dynein, light chain, LC8-type 1
Search

0.81	Dynein cytoplasmic light peptide variant 3

0.72	GO:0007017	microtubule-based process
0.50	GO:2000582	positive regulation of ATP-dependent microtubule motor activity, plus-end-directed
0.49	GO:0030705	cytoskeleton-dependent intracellular transport
0.49	GO:0060271	cilium assembly
0.45	GO:0006928	movement of cell or subcellular component
0.44	GO:1902857	positive regulation of non-motile cilium assembly
0.42	GO:0031503	protein complex localization
0.41	GO:0042326	negative regulation of phosphorylation
0.39	GO:0006886	intracellular protein transport
0.38	GO:0007286	spermatid development

0.52	GO:0045505	dynein intermediate chain binding
0.50	GO:0051959	dynein light intermediate chain binding
0.49	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed
0.44	GO:0008092	cytoskeletal protein binding
0.42	GO:0008022	protein C-terminus binding
0.41	GO:0019904	protein domain specific binding
0.39	GO:0097110	scaffold protein binding
0.39	GO:0042803	protein homodimerization activity
0.38	GO:0030235	nitric-oxide synthase regulator activity
0.37	GO:0046982	protein heterodimerization activity

0.79	GO:0030286	dynein complex
0.47	GO:0005813	centrosome
0.45	GO:0031475	myosin V complex
0.43	GO:0072686	mitotic spindle
0.43	GO:0008180	COP9 signalosome
0.43	GO:0000776	kinetochore
0.42	GO:0005929	cilium
0.39	GO:0005874	microtubule
0.39	GO:0005829	cytosol
0.37	GO:0120038	plasma membrane bounded cell projection part

0.49

EC:3.6.4.4

GO:0008574

sp|Q6PBH5|NDUA4_DANRE
Cytochrome c oxidase subunit NDUFA4
Search

NDUFA4

0.96	Mitochondrial NADH dehydrogenase 1 alpha subcomplex subunit 4

0.44	GO:1902600	hydrogen ion transmembrane transport
0.43	GO:0022900	electron transport chain
0.33	GO:0006119	oxidative phosphorylation
0.33	GO:0009060	aerobic respiration
0.32	GO:0035556	intracellular signal transduction

0.45	GO:0015002	heme-copper terminal oxidase activity
0.45	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.44	GO:0015078	hydrogen ion transmembrane transporter activity
0.43	GO:0009055	electron transfer activity
0.42	GO:0032403	protein complex binding
0.35	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.32	GO:0046872	metal ion binding

0.53	GO:0005751	mitochondrial respiratory chain complex IV
0.43	GO:0005747	mitochondrial respiratory chain complex I
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.45

GO:0016676

tr|Q6PBI0|Q6PBI0_DANRE
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial
Search

SUCLA2

0.70	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

0.70	GO:0006099	tricarboxylic acid cycle
0.39	GO:0006104	succinyl-CoA metabolic process
0.38	GO:0006105	succinate metabolic process
0.35	GO:0006780	uroporphyrinogen III biosynthetic process

0.67	GO:0004775	succinate-CoA ligase (ADP-forming) activity
0.55	GO:0000287	magnesium ion binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.59	GO:0005739	mitochondrion
0.47	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part

0.67	EC:6.2.1.5	GO:0004775
0.67	KEGG:R00405	GO:0004775

sp|Q6PBI2|PDPFB_DANRE
Pancreatic progenitor cell differentiation and proliferation factor B
Search

0.97	Pancreatic progenitor cell differentiation and proliferation factor B

0.71	GO:0030154	cell differentiation
0.69	GO:0007275	multicellular organism development
0.43	GO:0008283	cell proliferation

sp|Q6PBI4|HDA9B_DANRE
Histone deacetylase 9-B
Search

HDAC9

0.49	Histone deacetylase

0.80	GO:0016575	histone deacetylation
0.62	GO:0034983	peptidyl-lysine deacetylation
0.61	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis
0.58	GO:0032869	cellular response to insulin stimulus
0.55	GO:0000122	negative regulation of transcription by RNA polymerase II
0.54	GO:0006351	transcription, DNA-templated
0.49	GO:0040029	regulation of gene expression, epigenetic
0.43	GO:0048742	regulation of skeletal muscle fiber development
0.42	GO:0072359	circulatory system development
0.41	GO:0048513	animal organ development

0.80	GO:0004407	histone deacetylase activity
0.71	GO:0034979	NAD-dependent protein deacetylase activity
0.60	GO:0005080	protein kinase C binding
0.59	GO:0070491	repressing transcription factor binding
0.59	GO:0042826	histone deacetylase binding
0.51	GO:0046872	metal ion binding
0.41	GO:0003714	transcription corepressor activity

0.80	GO:0000118	histone deacetylase complex
0.53	GO:0005667	transcription factor complex
0.42	GO:0005737	cytoplasm
0.41	GO:0035097	histone methyltransferase complex
0.30	GO:0031224	intrinsic component of membrane

0.80

GO:0004407

sp|Q6PBI5|RS25_DANRE
40S ribosomal protein S25
Search

RPS25

0.77	Ribosomal protein S25

0.36	GO:0034198	cellular response to amino acid starvation
0.36	GO:0000028	ribosomal small subunit assembly
0.36	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.35	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.35	GO:0019083	viral transcription
0.35	GO:0006413	translational initiation
0.34	GO:0006364	rRNA processing

0.35	GO:0003723	RNA binding
0.34	GO:0003735	structural constituent of ribosome
0.34	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.44	GO:0005730	nucleolus
0.43	GO:0044445	cytosolic part
0.38	GO:0031012	extracellular matrix
0.38	GO:0070062	extracellular exosome
0.36	GO:0005844	polysome
0.34	GO:0005654	nucleoplasm

tr|Q6PBI6|Q6PBI6_DANRE
6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)
Search

0.59	Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha

0.80	GO:0046146	tetrahydrobiopterin metabolic process
0.80	GO:0034312	diol biosynthetic process
0.72	GO:0042559	pteridine-containing compound biosynthetic process
0.65	GO:0009108	coenzyme biosynthetic process
0.49	GO:0051291	protein heterooligomerization
0.49	GO:0051289	protein homotetramerization
0.44	GO:0045893	positive regulation of transcription, DNA-templated
0.38	GO:0055114	oxidation-reduction process
0.34	GO:0032774	RNA biosynthetic process
0.33	GO:0010467	gene expression

0.81	GO:0008124	4-alpha-hydroxytetrahydrobiopterin dehydratase activity
0.49	GO:0004505	phenylalanine 4-monooxygenase activity
0.36	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.34	GO:0005515	protein binding
0.33	GO:0003677	DNA binding

0.41	GO:0005634	nucleus
0.40	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part

0.81	EC:4.2.1.96	GO:0008124
0.81	KEGG:R04734	GO:0008124

sp|Q6PBI8|TM177_DANRE
Transmembrane protein 177
Search

TMEM177

0.79	Transmembrane protein 177

0.47

GO:0031305

integral component of mitochondrial inner membrane

tr|Q6PBJ0|Q6PBJ0_DANRE
Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, b
Search

ID2

0.97	Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, b

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.57	GO:0061031	endodermal digestive tract morphogenesis
0.56	GO:0045578	negative regulation of B cell differentiation
0.56	GO:0045777	positive regulation of blood pressure
0.56	GO:0048557	embryonic digestive tract morphogenesis
0.56	GO:0045664	regulation of neuron differentiation
0.55	GO:0003166	bundle of His development
0.55	GO:0090398	cellular senescence
0.55	GO:2000178	negative regulation of neural precursor cell proliferation
0.55	GO:0048715	negative regulation of oligodendrocyte differentiation

0.68	GO:0046983	protein dimerization activity
0.54	GO:0044325	ion channel binding
0.46	GO:0003677	DNA binding
0.40	GO:0043425	bHLH transcription factor binding
0.36	GO:0001085	RNA polymerase II transcription factor binding
0.34	GO:1901707	leptomycin B binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0019904	protein domain specific binding

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.43	GO:0043234	protein complex
0.34	GO:0000785	chromatin

tr|Q6PBJ1|Q6PBJ1_DANRE
Peptidylprolyl isomerase
Search

FKBP1B

0.61	Peptidyl-prolyl cis-trans isomerase FKBP1B

0.85	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.85	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity
0.84	GO:0033197	response to vitamin E
0.83	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus
0.83	GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.82	GO:0098870	action potential propagation
0.82	GO:0010459	negative regulation of heart rate
0.81	GO:0051280	negative regulation of release of sequestered calcium ion into cytosol
0.81	GO:0048680	positive regulation of axon regeneration
0.81	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling

0.81	GO:0019855	calcium channel inhibitor activity
0.77	GO:0005528	FK506 binding
0.76	GO:0044325	ion channel binding
0.70	GO:0030551	cyclic nucleotide binding
0.70	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.66	GO:0005102	receptor binding
0.54	GO:0005219	ryanodine-sensitive calcium-release channel activity

0.82	GO:0016529	sarcoplasmic reticulum
0.75	GO:0030018	Z disc
0.72	GO:0034704	calcium channel complex
0.69	GO:0098827	endoplasmic reticulum subcompartment
0.65	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.64	GO:0098588	bounding membrane of organelle
0.46	GO:0005829	cytosol

0.70

GO:0003755

sp|Q6PBJ2|CFA20_DANRE
Cilia- and flagella-associated protein 20
Search

CFAP20

0.89	Transcription factor IIB

0.79	GO:0060296	regulation of cilium beat frequency involved in ciliary motility
0.79	GO:2000253	positive regulation of feeding behavior
0.75	GO:0018095	protein polyglutamylation
0.70	GO:2000147	positive regulation of cell motility
0.69	GO:0060271	cilium assembly
0.39	GO:1901207	regulation of heart looping
0.39	GO:0014807	regulation of somitogenesis
0.38	GO:0065001	specification of axis polarity
0.36	GO:0006468	protein phosphorylation

0.36	GO:0004672	protein kinase activity
0.35	GO:0005515	protein binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003723	RNA binding

0.76	GO:0005929	cilium
0.72	GO:0005814	centriole
0.67	GO:0120038	plasma membrane bounded cell projection part
0.55	GO:0005634	nucleus
0.45	GO:0005874	microtubule
0.37	GO:0070062	extracellular exosome

tr|Q6PBJ3|Q6PBJ3_DANRE
VAMP/synaptobrevin
Search

0.74	Sodium channel epithelial 1 alpha subunit

0.69	GO:0016192	vesicle-mediated transport
0.53	GO:0090174	organelle membrane fusion
0.51	GO:0016050	vesicle organization
0.47	GO:0001921	positive regulation of receptor recycling
0.46	GO:0034446	substrate adhesion-dependent cell spreading
0.46	GO:0061951	establishment of protein localization to plasma membrane
0.46	GO:0071346	cellular response to interferon-gamma
0.46	GO:0032940	secretion by cell
0.45	GO:1903531	negative regulation of secretion by cell
0.45	GO:0043623	cellular protein complex assembly

0.46	GO:0000149	SNARE binding
0.46	GO:0005484	SNAP receptor activity
0.34	GO:0015280	ligand-gated sodium channel activity
0.34	GO:0050699	WW domain binding

0.51	GO:0031201	SNARE complex
0.49	GO:0099503	secretory vesicle
0.48	GO:0009986	cell surface
0.46	GO:0055037	recycling endosome
0.45	GO:0045335	phagocytic vesicle
0.45	GO:0030136	clathrin-coated vesicle
0.44	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0030659	cytoplasmic vesicle membrane
0.42	GO:0005829	cytosol
0.42	GO:0098588	bounding membrane of organelle

tr|Q6PBJ6|Q6PBJ6_DANRE
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6
Search

NDUFB6

0.97	NADH dehydrogenase 1 beta subcomplex subunit 6

0.63	GO:0032981	mitochondrial respiratory chain complex I assembly
0.53	GO:0042775	mitochondrial ATP synthesis coupled electron transport

0.39	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.34	GO:0016874	ligase activity

0.61	GO:0005747	mitochondrial respiratory chain complex I
0.52	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.39

GO:0008137

tr|Q6PBJ7|Q6PBJ7_DANRE
F-box and leucine-rich repeat protein 2
Search

FBXL2

0.87	F-box and leucine-rich repeat protein 2

0.80	GO:0001662	behavioral fear response
0.64	GO:0044830	modulation by host of viral RNA genome replication
0.59	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling
0.58	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.56	GO:0006513	protein monoubiquitination
0.53	GO:0010506	regulation of autophagy
0.39	GO:0000209	protein polyubiquitination
0.39	GO:0043687	post-translational protein modification
0.36	GO:0035556	intracellular signal transduction

0.62	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding
0.58	GO:0019903	protein phosphatase binding
0.55	GO:0004842	ubiquitin-protein transferase activity

0.58	GO:0019005	SCF ubiquitin ligase complex
0.37	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.55

GO:0004842

tr|Q6PBJ8|Q6PBJ8_DANRE
Peptidylprolyl isomerase
Search

0.43	Peptidylprolyl isomerase

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.54	GO:0051279	regulation of release of sequestered calcium ion into cytosol
0.52	GO:0042098	T cell proliferation
0.52	GO:1901019	regulation of calcium ion transmembrane transporter activity
0.52	GO:0050848	regulation of calcium-mediated signaling
0.52	GO:2001257	regulation of cation channel activity
0.51	GO:0051209	release of sequestered calcium ion into cytosol
0.50	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus
0.50	GO:0006936	muscle contraction
0.50	GO:0051284	positive regulation of sequestering of calcium ion

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.54	GO:0005528	FK506 binding
0.51	GO:0044325	ion channel binding
0.50	GO:0019855	calcium channel inhibitor activity
0.44	GO:0005102	receptor binding
0.40	GO:0042803	protein homodimerization activity
0.39	GO:0048185	activin binding
0.39	GO:0004672	protein kinase activity
0.39	GO:0046332	SMAD binding
0.37	GO:0005524	ATP binding

0.54	GO:0016529	sarcoplasmic reticulum
0.49	GO:0030018	Z disc
0.48	GO:0098827	endoplasmic reticulum subcompartment
0.47	GO:0034704	calcium channel complex
0.47	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.46	GO:0098588	bounding membrane of organelle
0.38	GO:0005829	cytosol
0.34	GO:0070062	extracellular exosome
0.34	GO:0031312	extrinsic component of organelle membrane
0.33	GO:0098562	cytoplasmic side of membrane

0.72

GO:0003755

tr|Q6PBJ9|Q6PBJ9_DANRE
Ribosomal protein, large P2
Search

0.78	Renal carcinoma antigen NY-REN-44

0.70	GO:0006414	translational elongation
0.44	GO:0002181	cytoplasmic translation
0.37	GO:0043009	chordate embryonic development
0.36	GO:1904401	cellular response to Thyroid stimulating hormone
0.35	GO:0071320	cellular response to cAMP
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0045727	positive regulation of translation
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription
0.33	GO:0006413	translational initiation

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0043021	ribonucleoprotein complex binding
0.33	GO:0005506	iron ion binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.46	GO:0044445	cytosolic part
0.41	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|Q6PBK1|CCD58_DANRE
Coiled-coil domain-containing protein 58
Search

CCDC58

0.96	Coiled-coil domain-containing protein 58

0.61

GO:0005739

mitochondrion

sp|Q6PBK3|RS28_DANRE
40S ribosomal protein S28
Search

RPS28

0.82	Ribosomal protein S28 pseudogene 9

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.50	GO:0042274	ribosomal small subunit biogenesis
0.47	GO:0016072	rRNA metabolic process
0.45	GO:0042255	ribosome assembly
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.64	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.34	GO:0004815	aspartate-tRNA ligase activity
0.34	GO:0005515	protein binding
0.33	GO:0051539	4 iron, 4 sulfur cluster binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046872	metal ion binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.51	GO:0005844	polysome
0.49	GO:0044445	cytosolic part
0.43	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0005634	nucleus
0.34	GO:0019008	molybdopterin synthase complex
0.33	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:6.1.1.12

GO:0004815

tr|Q6PBK4|Q6PBK4_DANRE
Phosphatidylinositol glycan anchor biosynthesis, class P
Search

PIGP

0.94	Phosphatidylinositol N-acetylglucosaminyltransferase subunit P

0.76	GO:0006506	GPI anchor biosynthetic process
0.48	GO:1904103	regulation of convergent extension involved in gastrulation
0.46	GO:0060028	convergent extension involved in axis elongation
0.44	GO:0046328	regulation of JNK cascade
0.34	GO:0032259	methylation
0.34	GO:0045454	cell redox homeostasis
0.32	GO:0055114	oxidation-reduction process
0.32	GO:0005975	carbohydrate metabolic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.81	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity
0.35	GO:0070569	uridylyltransferase activity
0.34	GO:0004077	biotin-[acetyl-CoA-carboxylase] ligase activity
0.34	GO:0008168	methyltransferase activity
0.33	GO:0004565	beta-galactosidase activity
0.33	GO:0015002	heme-copper terminal oxidase activity
0.32	GO:0003700	DNA binding transcription factor activity

0.50	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
0.30	GO:0016021	integral component of membrane

0.81

EC:2.4.1.198

GO:0017176

sp|Q6PBK8|RPRMB_DANRE
Protein reprimo B
Search

RPRM

0.95	Reprimo like

0.68	GO:0007050	cell cycle arrest
0.63	GO:0007346	regulation of mitotic cell cycle

0.33

GO:0005515

protein binding

0.38	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q6PBL0|TIM16_DANRE
Mitochondrial import inner membrane translocase subunit tim16
Search

0.78	Mitochondrial import inner membrane translocase subunit 16

0.78	GO:0030150	protein import into mitochondrial matrix
0.38	GO:0001503	ossification
0.37	GO:0032780	negative regulation of ATPase activity
0.36	GO:2001234	negative regulation of apoptotic signaling pathway
0.35	GO:1902511	negative regulation of apoptotic DNA fragmentation
0.35	GO:0090199	regulation of release of cytochrome c from mitochondria
0.35	GO:0010823	negative regulation of mitochondrion organization
0.34	GO:0071897	DNA biosynthetic process
0.34	GO:0007030	Golgi organization
0.34	GO:0030010	establishment of cell polarity

0.35	GO:0019904	protein domain specific binding
0.34	GO:0008566	mitochondrial protein-transporting ATPase activity
0.32	GO:0003844	1,4-alpha-glucan branching enzyme activity
0.32	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.31	GO:0016491	oxidoreductase activity
0.31	GO:0043169	cation binding

0.78	GO:0005744	mitochondrial inner membrane presequence translocase complex
0.46	GO:0005794	Golgi apparatus
0.37	GO:0031314	extrinsic component of mitochondrial inner membrane
0.36	GO:0005759	mitochondrial matrix
0.30	GO:0016021	integral component of membrane

0.34

EC:3.6.3.51

GO:0008566

tr|Q6PBL4|Q6PBL4_DANRE
Polymerase (DNA directed), epsilon 3 (p17 subunit)
Search

POLE3

0.95	DNA polymerase epsilon subunit 3

0.53	GO:0043966	histone H3 acetylation
0.38	GO:0071897	DNA biosynthetic process
0.36	GO:0043044	ATP-dependent chromatin remodeling
0.35	GO:0032201	telomere maintenance via semi-conservative replication
0.35	GO:0031055	chromatin remodeling at centromere
0.35	GO:0061641	CENP-A containing chromatin organization
0.35	GO:0071480	cellular response to gamma radiation
0.35	GO:0042766	nucleosome mobilization
0.35	GO:0006336	DNA replication-independent nucleosome assembly
0.35	GO:0034508	centromere complex assembly

0.74	GO:0046982	protein heterodimerization activity
0.39	GO:0003887	DNA-directed DNA polymerase activity
0.35	GO:0003677	DNA binding
0.35	GO:0031491	nucleosome binding
0.34	GO:0004402	histone acetyltransferase activity
0.33	GO:0004386	helicase activity
0.33	GO:0004655	porphobilinogen synthase activity
0.33	GO:0016887	ATPase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.58	GO:0005634	nucleus
0.50	GO:0031248	protein acetyltransferase complex
0.49	GO:0042575	DNA polymerase complex
0.47	GO:0044427	chromosomal part
0.46	GO:0031974	membrane-enclosed lumen
0.43	GO:0043234	protein complex
0.34	GO:1904949	ATPase complex

0.39	EC:2.7.7.7	GO:0003887
0.33	KEGG:R00036	GO:0004655

tr|Q6PBL5|Q6PBL5_DANRE
Family with sequence similarity 3, member A
Search

0.10	Family 3, member A protein isoform 1

0.49	GO:0046676	negative regulation of insulin secretion
0.42	GO:1905035	negative regulation of antifungal innate immune response
0.40	GO:0019732	antifungal humoral response
0.40	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.37	GO:0006098	pentose-phosphate shunt
0.37	GO:0006006	glucose metabolic process
0.34	GO:0055114	oxidation-reduction process
0.34	GO:0010469	regulation of receptor activity
0.34	GO:0009062	fatty acid catabolic process
0.34	GO:0030258	lipid modification

0.38	GO:0004345	glucose-6-phosphate dehydrogenase activity
0.36	GO:0050661	NADP binding
0.35	GO:0033791	3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity
0.35	GO:0005125	cytokine activity
0.34	GO:0003997	acyl-CoA oxidase activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.38	GO:0005576	extracellular region
0.34	GO:0042579	microbody
0.34	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

0.38

EC:1.1.1.49

GO:0004345

tr|Q6PBL7|Q6PBL7_DANRE
Transmembrane protein 126A
Search

TMEM126A

0.49	Transmembrane protein 126A

0.46

GO:0021554

optic nerve development

0.39	GO:0005739	mitochondrion
0.35	GO:0019866	organelle inner membrane
0.30	GO:0044425	membrane part

sp|Q6PBM1|GLRX5_DANRE
Glutaredoxin-related protein 5, mitochondrial
Search

GLRX5

0.43	Glutaredoxin

0.69	GO:0045454	cell redox homeostasis
0.61	GO:0022900	electron transport chain
0.47	GO:0009249	protein lipoylation
0.45	GO:0030097	hemopoiesis
0.43	GO:0016226	iron-sulfur cluster assembly
0.32	GO:0044281	small molecule metabolic process

0.72	GO:0015035	protein disulfide oxidoreductase activity
0.65	GO:0051537	2 iron, 2 sulfur cluster binding
0.62	GO:0009055	electron transfer activity
0.51	GO:0046872	metal ion binding
0.35	GO:0004491	methylmalonate-semialdehyde dehydrogenase (acylating) activity
0.33	GO:0005515	protein binding

0.46	GO:0005759	mitochondrial matrix
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.34	GO:0005634	nucleus

0.35

EC:1.2.1.27

GO:0004491

tr|Q6PBM2|Q6PBM2_DANRE
Elongation of very long chain fatty acids protein 4
Search

ELOVL4

0.55	Elongation of very long chain fatty acids protein 4

0.76	GO:0019367	fatty acid elongation, saturated fatty acid
0.75	GO:0042761	very long-chain fatty acid biosynthetic process
0.74	GO:0034626	fatty acid elongation, polyunsaturated fatty acid
0.74	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.70	GO:0006636	unsaturated fatty acid biosynthetic process
0.49	GO:0034625	fatty acid elongation, monounsaturated fatty acid
0.47	GO:0030148	sphingolipid biosynthetic process
0.34	GO:0009584	detection of visible light

0.82	GO:0102756	very-long-chain 3-ketoacyl-CoA synthase activity
0.82	GO:0102338	3-oxo-lignoceronyl-CoA synthase activity
0.82	GO:0102336	3-oxo-arachidoyl-CoA synthase activity
0.82	GO:0102337	3-oxo-cerotoyl-CoA synthase activity
0.74	GO:0009922	fatty acid elongase activity
0.35	GO:0008020	G-protein coupled photoreceptor activity
0.33	GO:0005515	protein binding

0.63	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.82

EC:2.3.1.199

GO:0102338

sp|Q6PBM7|FA76B_DANRE
Protein FAM76B
Search

0.36

GO:0006413

translational initiation

0.36	GO:0003743	translation initiation factor activity
0.35	GO:0005515	protein binding

0.73	GO:0016607	nuclear speck
0.30	GO:0044425	membrane part

sp|Q6PBM8|RBM18_DANRE
Probable RNA-binding protein 18
Search

RBM18

0.94	RNA binding motif protein 18

0.33	GO:0006438	valyl-tRNA aminoacylation
0.33	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.32	GO:0006396	RNA processing

0.59	GO:0003723	RNA binding
0.33	GO:0004832	valine-tRNA ligase activity
0.33	GO:0002161	aminoacyl-tRNA editing activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032553	ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0016021

integral component of membrane

0.33	EC:6.1.1.9	GO:0004832
0.33	KEGG:R03665	GO:0004832

tr|Q6PBN0|Q6PBN0_DANRE
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
Search

NDUFB2

0.41	Mitochondrial NADH dehydrogenase 1 beta subcomplex subunit 2

0.53	GO:0032981	mitochondrial respiratory chain complex I assembly
0.35	GO:0055114	oxidation-reduction process
0.33	GO:0006119	oxidative phosphorylation

0.34

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.82	GO:0005747	mitochondrial respiratory chain complex I
0.30	GO:0016021	integral component of membrane

0.34

GO:0008137

sp|Q6PBN2|AIDA_DANRE
Axin interactor, dorsalization-associated protein
Search

AIDA

0.97	Axin interaction partner and dorsalization antagonist

0.86	GO:0043508	negative regulation of JUN kinase activity
0.81	GO:0043496	regulation of protein homodimerization activity
0.77	GO:0048264	determination of ventral identity
0.66	GO:2000016	negative regulation of determination of dorsal identity
0.47	GO:0035556	intracellular signal transduction
0.45	GO:0030178	negative regulation of Wnt signaling pathway

0.67	GO:0019904	protein domain specific binding
0.65	GO:0035091	phosphatidylinositol binding

0.45	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q6PBN3|Q6PBN3_DANRE
Peripherin 2b (retinal degeneration, slow)
Search

PRPH2

0.97	Retinal degeneration, slow (Retinitis pigmentosa 7)

0.78	GO:0007601	visual perception
0.53	GO:0060041	retina development in camera-type eye
0.44	GO:0007166	cell surface receptor signaling pathway
0.39	GO:0007155	cell adhesion
0.35	GO:1903525	regulation of membrane tubulation
0.35	GO:0009645	response to low light intensity stimulus
0.34	GO:0051289	protein homotetramerization
0.34	GO:0051258	protein polymerization

0.34

GO:0005515

protein binding

0.54	GO:0001750	photoreceptor outer segment
0.42	GO:0005887	integral component of plasma membrane
0.34	GO:0055037	recycling endosome
0.34	GO:0005795	Golgi stack
0.33	GO:0005783	endoplasmic reticulum
0.33	GO:0043234	protein complex

sp|Q6PBN4|CQ10X_DANRE
Coenzyme Q-binding protein COQ10 homolog, mitochondrial
Search

COQ10B

0.92	Coenzyme Q-binding protein COQ10 like protein B, mitochondrial

0.74	GO:0006744	ubiquinone biosynthetic process
0.61	GO:0045333	cellular respiration

0.86

GO:0048039

ubiquinone binding

0.61	GO:0005739	mitochondrion
0.47	GO:0019866	organelle inner membrane

sp|Q6PBN5|AUP1_DANRE
Ancient ubiquitous protein 1
Search

AUP1

0.97	Ancient ubiquitous protein 1

0.56	GO:1903513	endoplasmic reticulum to cytosol transport
0.56	GO:0032527	protein exit from endoplasmic reticulum
0.55	GO:0036503	ERAD pathway
0.44	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.41	GO:0050790	regulation of catalytic activity
0.34	GO:0016579	protein deubiquitination

0.46	GO:0097027	ubiquitin-protein transferase activator activity
0.45	GO:0043130	ubiquitin binding
0.38	GO:0016746	transferase activity, transferring acyl groups
0.34	GO:0004843	thiol-dependent ubiquitin-specific protease activity

0.47	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex
0.44	GO:0030176	integral component of endoplasmic reticulum membrane
0.35	GO:0070062	extracellular exosome

0.38

EC:2.3

GO:0016746

tr|Q6PBN6|Q6PBN6_DANRE
Kinase
Search

IP6K2

0.53

Kinase

0.83	GO:0032958	inositol phosphate biosynthetic process
0.57	GO:0016310	phosphorylation
0.53	GO:0007227	signal transduction downstream of smoothened
0.51	GO:0045880	positive regulation of smoothened signaling pathway
0.36	GO:0030308	negative regulation of cell growth
0.36	GO:0043065	positive regulation of apoptotic process
0.35	GO:0046488	phosphatidylinositol metabolic process
0.35	GO:0030258	lipid modification

0.60	GO:0016301	kinase activity
0.35	GO:0016776	phosphotransferase activity, phosphate group as acceptor

0.36	GO:0001650	fibrillar center
0.35	GO:0030054	cell junction

0.35

EC:2.7.4

GO:0016776

tr|Q6PBN9|Q6PBN9_DANRE
Guanine nucleotide-binding protein subunit gamma
Search

0.71	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.49	GO:0042462	eye photoreceptor cell development
0.47	GO:0007602	phototransduction
0.42	GO:0008104	protein localization
0.39	GO:0010659	cardiac muscle cell apoptotic process
0.37	GO:0071456	cellular response to hypoxia
0.35	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.35	GO:0071377	cellular response to glucagon stimulus
0.34	GO:0071482	cellular response to light stimulus
0.34	GO:0009584	detection of visible light

0.64	GO:0004871	signal transducer activity
0.40	GO:0003924	GTPase activity
0.34	GO:0005515	protein binding
0.34	GO:0003995	acyl-CoA dehydrogenase activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.81	GO:1905360	GTPase complex
0.80	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.66	GO:0098797	plasma membrane protein complex
0.38	GO:0001750	photoreceptor outer segment
0.38	GO:0001917	photoreceptor inner segment
0.36	GO:0060170	ciliary membrane

0.34

EC:1.3.99.3

GO:0003995

tr|Q6PBP0|Q6PBP0_DANRE
Cytochrome c oxidase, subunit VIIc
Search

COX7C

0.95	Cytochrome c oxidase polypeptide VIIc

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.44	GO:0006119	oxidative phosphorylation
0.44	GO:0009060	aerobic respiration

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.52	GO:0005751	mitochondrial respiratory chain complex IV
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016676

tr|Q6PBP2|Q6PBP2_DANRE
X-ray repair complementing defective repair in Chinese hamster cells 4
Search

XRCC4

0.88	X-ray repair-complementing defective repair in Chinese hamster cells 4

0.76	GO:0006302	double-strand break repair
0.65	GO:0006310	DNA recombination
0.62	GO:0051351	positive regulation of ligase activity
0.62	GO:0000726	non-recombinational repair
0.61	GO:0010165	response to X-ray
0.56	GO:0051103	DNA ligation involved in DNA repair
0.39	GO:0002328	pro-B cell differentiation
0.39	GO:1905765	negative regulation of protection from non-homologous end joining at telomere
0.39	GO:0071285	cellular response to lithium ion
0.38	GO:0002208	somatic diversification of immunoglobulins involved in immune response

0.58	GO:0008022	protein C-terminus binding
0.55	GO:0003677	DNA binding
0.53	GO:0042802	identical protein binding
0.39	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity
0.35	GO:0016874	ligase activity

0.63	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex
0.62	GO:0032807	DNA ligase IV complex
0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.39	GO:0070522	ERCC4-ERCC1 complex
0.37	GO:0000784	nuclear chromosome, telomeric region
0.37	GO:0000793	condensed chromosome

0.35

GO:0016874

sp|Q6PBP3|F213A_DANRE
Redox-regulatory protein FAM213A
Search

FAM213A

0.95	selenoprotein U

0.59	GO:0045670	regulation of osteoclast differentiation
0.53	GO:0098869	cellular oxidant detoxification
0.52	GO:0055114	oxidation-reduction process

0.53	GO:0016209	antioxidant activity
0.33	GO:0016491	oxidoreductase activity

0.41	GO:0005737	cytoplasm
0.37	GO:0005576	extracellular region
0.36	GO:0043227	membrane-bounded organelle
0.35	GO:0043229	intracellular organelle
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016491

tr|Q6PBP6|Q6PBP6_DANRE
Coiled-coil-helix-coiled-coil-helix domain containing 10
Search

CHCHD10

0.89	Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

0.61	GO:0007005	mitochondrion organization
0.61	GO:1900037	regulation of cellular response to hypoxia
0.56	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:2000984	negative regulation of ATP citrate synthase activity
0.42	GO:0006091	generation of precursor metabolites and energy
0.42	GO:0006754	ATP biosynthetic process
0.42	GO:0009250	glucan biosynthetic process
0.41	GO:0016310	phosphorylation
0.38	GO:0036211	protein modification process
0.37	GO:0044267	cellular protein metabolic process

0.52	GO:0008134	transcription factor binding
0.50	GO:0043565	sequence-specific DNA binding
0.45	GO:0004689	phosphorylase kinase activity
0.43	GO:0005516	calmodulin binding
0.38	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0005758	mitochondrial intermembrane space
0.54	GO:0005634	nucleus
0.45	GO:0005964	phosphorylase kinase complex
0.30	GO:0016020	membrane

0.45

EC:2.7.11.19

GO:0004689

sp|Q6PBQ2|CHMP7_DANRE
Charged multivesicular body protein 7
Search

CHMP7

0.90	Charged multivesicular body protein 7

0.77	GO:0007034	vacuolar transport
0.60	GO:0010458	exit from mitosis
0.60	GO:0031468	nuclear envelope reassembly
0.58	GO:0071168	protein localization to chromatin
0.57	GO:0000920	cell separation after cytokinesis
0.57	GO:0007080	mitotic metaphase plate congression
0.55	GO:0016197	endosomal transport
0.50	GO:0016192	vesicle-mediated transport
0.49	GO:0015031	protein transport
0.36	GO:1904903	ESCRT III complex disassembly

0.51	GO:0008565	protein transporter activity
0.33	GO:0005515	protein binding
0.33	GO:0003676	nucleic acid binding

0.60	GO:0000815	ESCRT III complex
0.54	GO:0005635	nuclear envelope
0.50	GO:0000785	chromatin
0.49	GO:0005829	cytosol

tr|Q6PBR4|Q6PBR4_DANRE
Guanine nucleotide-binding protein subunit gamma
Search

GNGT2

0.71	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.39	GO:0042462	eye photoreceptor cell development
0.39	GO:0007602	phototransduction
0.36	GO:0008104	protein localization
0.35	GO:0071377	cellular response to glucagon stimulus
0.32	GO:0055114	oxidation-reduction process

0.64	GO:0004871	signal transducer activity
0.43	GO:0003924	GTPase activity
0.33	GO:0003995	acyl-CoA dehydrogenase activity
0.33	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0005515	protein binding

0.81	GO:1905360	GTPase complex
0.80	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.66	GO:0098797	plasma membrane protein complex

0.33

EC:1.3.99.3

GO:0003995

tr|Q6PBR5|Q6PBR5_DANRE
V-type proton ATPase subunit G
Search

ATP6V1G1

0.69	V-type proton ATPase subunit G

0.62	GO:0015992	proton transport
0.55	GO:0055085	transmembrane transport
0.53	GO:0036295	cellular response to increased oxygen levels
0.48	GO:0006879	cellular iron ion homeostasis
0.37	GO:0090383	phagosome acidification
0.36	GO:0033572	transferrin transport
0.36	GO:0008286	insulin receptor signaling pathway
0.36	GO:0016241	regulation of macroautophagy

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.52	GO:0051117	ATPase binding
0.47	GO:0022853	active ion transmembrane transporter activity
0.44	GO:0015078	hydrogen ion transmembrane transporter activity

0.82	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.48	GO:0005765	lysosomal membrane
0.45	GO:0030285	integral component of synaptic vesicle membrane
0.45	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.37	GO:0042470	melanosome
0.36	GO:0070062	extracellular exosome

sp|Q6PBR7|RT63_DANRE
Ribosomal protein 63, mitochondrial
Search

MRPL57

0.96	Mitochondrial ribosomal protein 63

0.38

GO:0006412

translation

0.39

GO:0003735

structural constituent of ribosome

0.79

GO:0005761

mitochondrial ribosome

tr|Q6PBS0|Q6PBS0_DANRE
Required for meiotic nuclear division 5 homolog B
Search

RMND5B

0.97	Required for meiotic nuclear division 5 homolog B

0.63	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.60	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

0.57	GO:0004842	ubiquitin-protein transferase activity
0.50	GO:0046872	metal ion binding

0.68	GO:0034657	GID complex
0.50	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm

0.57

GO:0004842

sp|Q6PBS6|TM258_DANRE
Transmembrane protein 258
Search

TMEM258

0.60	Transmembrane domain-containing protein (Fragment)

0.80

GO:0006487

protein N-linked glycosylation

0.85	GO:0034998	oligosaccharyltransferase I complex
0.30	GO:0031224	intrinsic component of membrane

tr|Q6PBS8|Q6PBS8_DANRE
Chchd2l protein
Search

CHCHD2

0.94	Coiled-coil-helix-coiled-coil-helix domain containing

0.71	GO:1900037	regulation of cellular response to hypoxia
0.65	GO:0045944	positive regulation of transcription by RNA polymerase II
0.61	GO:0007005	mitochondrion organization
0.47	GO:0005978	glycogen biosynthetic process
0.43	GO:0009060	aerobic respiration
0.42	GO:0006468	protein phosphorylation
0.37	GO:0006351	transcription, DNA-templated

0.59	GO:0008134	transcription factor binding
0.57	GO:0043565	sequence-specific DNA binding
0.51	GO:0004689	phosphorylase kinase activity
0.48	GO:0005516	calmodulin binding
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0032947	protein complex scaffold activity

0.68	GO:0005758	mitochondrial intermembrane space
0.56	GO:0005634	nucleus
0.51	GO:0005964	phosphorylase kinase complex
0.30	GO:0031224	intrinsic component of membrane

0.51

EC:2.7.11.19

GO:0004689

tr|Q6PBT1|Q6PBT1_DANRE
40S ribosomal protein S27
Search

0.71	40S ribosomal protein S27

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.48	GO:0000028	ribosomal small subunit assembly
0.47	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.46	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.46	GO:0031571	mitotic G1 DNA damage checkpoint
0.45	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.43	GO:0045727	positive regulation of translation

0.64	GO:0003735	structural constituent of ribosome
0.54	GO:0046872	metal ion binding
0.47	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.47	GO:0008494	translation activator activity
0.35	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.32	GO:0003677	DNA binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.46	GO:0044445	cytosolic part
0.42	GO:0005634	nucleus
0.41	GO:0044446	intracellular organelle part
0.33	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

tr|Q6PBT3|Q6PBT3_DANRE
Fasciculation and elongation protein zeta 1 (Zygin I)
Search

FEZ1

0.97	Fasciculation and elongation protein zeta-1

0.84	GO:1902902	negative regulation of autophagosome assembly
0.64	GO:0007411	axon guidance
0.49	GO:0061880	regulation of anterograde axonal transport of mitochondrion
0.46	GO:0070584	mitochondrion morphogenesis
0.45	GO:0051654	establishment of mitochondrion localization
0.45	GO:0021766	hippocampus development
0.44	GO:0010976	positive regulation of neuron projection development
0.44	GO:0032388	positive regulation of intracellular transport
0.44	GO:0030010	establishment of cell polarity
0.44	GO:0051272	positive regulation of cellular component movement

0.68	GO:0043015	gamma-tubulin binding
0.45	GO:0005080	protein kinase C binding
0.45	GO:0047485	protein N-terminus binding

0.65	GO:0005813	centrosome
0.65	GO:0030424	axon
0.62	GO:0005794	Golgi apparatus
0.45	GO:0030426	growth cone
0.44	GO:0043025	neuronal cell body
0.44	GO:0030425	dendrite
0.42	GO:0005874	microtubule
0.38	GO:0005739	mitochondrion
0.37	GO:0005886	plasma membrane

tr|Q6PBT4|Q6PBT4_DANRE
Dual specificity protein phosphatase
Search

DUSP5

0.72	Dual specificity protein phosphatase

0.85	GO:0000188	inactivation of MAPK activity
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.57	GO:0035970	peptidyl-threonine dephosphorylation
0.50	GO:0001706	endoderm formation
0.44	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.38	GO:0042981	regulation of apoptotic process
0.35	GO:0045906	negative regulation of vasoconstriction
0.34	GO:0000187	activation of MAPK activity
0.34	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.34	GO:0045934	negative regulation of nucleobase-containing compound metabolic process

0.85	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.75	GO:0004725	protein tyrosine phosphatase activity
0.46	GO:0008330	protein tyrosine/threonine phosphatase activity
0.45	GO:1990439	MAP kinase serine/threonine phosphatase activity
0.34	GO:0019838	growth factor binding
0.33	GO:0016301	kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008144	drug binding

0.41	GO:0005634	nucleus
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.35	GO:0005737	cytoplasm
0.33	GO:0005694	chromosome
0.30	GO:0016021	integral component of membrane

0.85

GO:0017017

sp|Q6PBT5|PYRD1_DANRE
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1
Search

PYROXD1

0.95	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1

0.51	GO:0055114	oxidation-reduction process
0.50	GO:0034599	cellular response to oxidative stress

0.52	GO:0016491	oxidoreductase activity
0.33	GO:0005515	protein binding

0.53	GO:0030017	sarcomere
0.44	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.52

GO:0016491

sp|Q6PBT6|GFRP_DANRE
GTP cyclohydrolase 1 feedback regulatory protein
Search

GCHFR

0.97	GTP cyclohydrolase I feedback regulator

0.69	GO:0009890	negative regulation of biosynthetic process
0.42	GO:0043105	negative regulation of GTP cyclohydrolase I activity
0.40	GO:0051291	protein heterooligomerization
0.35	GO:0001505	regulation of neurotransmitter levels
0.35	GO:1903426	regulation of reactive oxygen species biosynthetic process
0.35	GO:1903409	reactive oxygen species biosynthetic process
0.34	GO:2001057	reactive nitrogen species metabolic process
0.33	GO:0051186	cofactor metabolic process
0.33	GO:0017144	drug metabolic process
0.33	GO:0031326	regulation of cellular biosynthetic process

0.47	GO:0016787	hydrolase activity
0.42	GO:0044549	GTP cyclohydrolase binding
0.40	GO:0030742	GTP-dependent protein binding
0.38	GO:0016597	amino acid binding
0.38	GO:0004857	enzyme inhibitor activity

0.55	GO:0042470	melanosome
0.54	GO:0031965	nuclear membrane
0.53	GO:0030425	dendrite
0.48	GO:0005654	nucleoplasm
0.39	GO:0005829	cytosol
0.36	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.47

GO:0016787

sp|Q6PBT7|TIM14_DANRE
Mitochondrial import inner membrane translocase subunit TIM14
Search

DNAJC19

0.88	Mitochondrial import inner membrane translocase subunit 14

0.59	GO:0048806	genitalia development
0.55	GO:0007601	visual perception
0.44	GO:0015031	protein transport
0.40	GO:0072655	establishment of protein localization to mitochondrion
0.40	GO:0006839	mitochondrial transport
0.39	GO:0007005	mitochondrion organization
0.38	GO:0046907	intracellular transport
0.37	GO:0032781	positive regulation of ATPase activity
0.36	GO:0006457	protein folding
0.36	GO:0055085	transmembrane transport

0.42	GO:0008566	mitochondrial protein-transporting ATPase activity
0.37	GO:0001671	ATPase activator activity
0.35	GO:0005515	protein binding
0.35	GO:0008237	metallopeptidase activity
0.34	GO:0008270	zinc ion binding

0.49	GO:0031966	mitochondrial membrane
0.49	GO:0019866	organelle inner membrane
0.46	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.42

EC:3.6.3.51

GO:0008566

sp|Q6PBT8|FGF1_DANRE
Putative fibroblast growth factor 1
Search

FGF1

0.46	Multifunctional fusion protein (Fragment)

0.82	GO:0051781	positive regulation of cell division
0.81	GO:0008543	fibroblast growth factor receptor signaling pathway
0.79	GO:0001525	angiogenesis
0.74	GO:0010469	regulation of receptor activity
0.70	GO:0030154	cell differentiation
0.59	GO:0060681	branch elongation involved in ureteric bud branching
0.58	GO:1901509	regulation of endothelial tube morphogenesis
0.58	GO:0045542	positive regulation of cholesterol biosynthetic process
0.57	GO:2000544	regulation of endothelial cell chemotaxis to fibroblast growth factor
0.56	GO:0032148	activation of protein kinase B activity

0.83	GO:0005104	fibroblast growth factor receptor binding
0.81	GO:0008201	heparin binding
0.76	GO:0008083	growth factor activity
0.55	GO:0044548	S100 protein binding
0.54	GO:0005178	integrin binding
0.35	GO:0030544	Hsp70 protein binding
0.33	GO:0016740	transferase activity

0.74	GO:0005938	cell cortex
0.67	GO:0005829	cytosol
0.65	GO:0005576	extracellular region
0.60	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0044446	intracellular organelle part

0.33

GO:0016740

sp|Q6PBT9|Z385B_DANRE
Zinc finger protein 385B
Search

ZNF385B

0.74	Zinc finger protein 385B

0.55

GO:0072332

intrinsic apoptotic signaling pathway by p53 class mediator

0.62	GO:0008270	zinc ion binding
0.54	GO:0002039	p53 binding
0.50	GO:0003676	nucleic acid binding

0.51	GO:0001650	fibrillar center
0.30	GO:0044425	membrane part

sp|Q6PBU0|F136A_DANRE
Protein FAM136A
Search

0.56	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

tr|Q6PBU2|Q6PBU2_DANRE
Vacuolar protein sorting 37A
Search

VPS37A

0.95	LOW QUALITY PROTEIN: vacuolar protein sorting-associated protein 37A

0.80	GO:0032509	endosome transport via multivesicular body sorting pathway
0.64	GO:0015031	protein transport
0.49	GO:0007626	locomotory behavior
0.38	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
0.36	GO:0036258	multivesicular body assembly
0.35	GO:0016236	macroautophagy
0.35	GO:0039702	viral budding via host ESCRT complex
0.35	GO:0036211	protein modification process
0.35	GO:0075733	intracellular transport of virus

0.34

GO:0005515

protein binding

0.81	GO:0000813	ESCRT I complex
0.38	GO:0005813	centrosome
0.38	GO:0031902	late endosome membrane
0.36	GO:0005654	nucleoplasm
0.36	GO:0005829	cytosol
0.34	GO:0044216	other organism cell
0.34	GO:0018995	host

tr|Q6PBU4|Q6PBU4_DANRE
Eukaryotic translation initiation factor 4E class II 2B
Search

EIF4E2

0.92	Eukaryotic translation initiation factor 4E member 2

0.72	GO:0006413	translational initiation
0.49	GO:0001701	in utero embryonic development
0.46	GO:0017148	negative regulation of translation
0.34	GO:0055114	oxidation-reduction process

0.73	GO:0003743	translation initiation factor activity
0.47	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.35	GO:0005509	calcium ion binding
0.35	GO:0020037	heme binding
0.35	GO:0005506	iron ion binding
0.34	GO:0000339	RNA cap binding

0.50	GO:0005845	mRNA cap binding complex
0.49	GO:0005737	cytoplasm

0.36

EC:1.14

GO:0016705

sp|Q6PBU5|GRT1A_DANRE
Growth hormone-regulated TBC protein 1-A
Search

GRTP1

0.94	Growth hormone-regulated TBC protein 1-A

0.75	GO:0031338	regulation of vesicle fusion
0.75	GO:0090630	activation of GTPase activity
0.62	GO:0006886	intracellular protein transport
0.36	GO:0010469	regulation of receptor activity

0.72	GO:0017137	Rab GTPase binding
0.69	GO:0005096	GTPase activator activity
0.41	GO:0016787	hydrolase activity
0.36	GO:0005179	hormone activity

0.61	GO:0012505	endomembrane system
0.42	GO:0005622	intracellular
0.35	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

0.41

GO:0016787

tr|Q6PBU6|Q6PBU6_DANRE
Synaptotagmin IV
Search

SYT4

0.96	Synaptotagmin IV

0.73	GO:0006887	exocytosis
0.58	GO:0033604	negative regulation of catecholamine secretion
0.56	GO:1903861	positive regulation of dendrite extension
0.52	GO:0017158	regulation of calcium ion-dependent exocytosis
0.51	GO:1905433	negative regulation of retrograde trans-synaptic signaling by neuropeptide
0.51	GO:0048174	negative regulation of short-term neuronal synaptic plasticity
0.50	GO:0007269	neurotransmitter secretion
0.49	GO:0014049	positive regulation of glutamate secretion
0.48	GO:0050709	negative regulation of protein secretion
0.48	GO:0014059	regulation of dopamine secretion

0.50	GO:0005544	calcium-dependent phospholipid binding
0.48	GO:0000149	SNARE binding
0.46	GO:0030276	clathrin binding
0.46	GO:0005509	calcium ion binding
0.39	GO:0042803	protein homodimerization activity
0.38	GO:0048487	beta-tubulin binding
0.38	GO:0031369	translation initiation factor binding
0.38	GO:0001786	phosphatidylserine binding
0.37	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0046982	protein heterodimerization activity

0.50	GO:1990742	microvesicle
0.49	GO:0098793	presynapse
0.49	GO:0097449	astrocyte projection
0.49	GO:0031045	dense core granule
0.46	GO:0043005	neuron projection
0.46	GO:0043025	neuronal cell body
0.45	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0120038	plasma membrane bounded cell projection part
0.43	GO:0005794	Golgi apparatus
0.43	GO:0005886	plasma membrane

sp|Q6PBU7|UQCC2_DANRE
Ubiquinol-cytochrome-c reductase complex assembly factor 2
Search

UQCC2

0.97	Mitochondrial ubiquinol-cytochrome-c reductase complex assembly factor 2

0.83	GO:0017062	respiratory chain complex III assembly
0.83	GO:0097033	mitochondrial respiratory chain complex III biogenesis
0.80	GO:0033108	mitochondrial respiratory chain complex assembly
0.61	GO:0002082	regulation of oxidative phosphorylation
0.60	GO:2001014	regulation of skeletal muscle cell differentiation
0.60	GO:0070131	positive regulation of mitochondrial translation
0.58	GO:0050796	regulation of insulin secretion
0.56	GO:1903364	positive regulation of cellular protein catabolic process
0.40	GO:0032958	inositol phosphate biosynthetic process
0.36	GO:0016310	phosphorylation

0.36	GO:0016301	kinase activity
0.33	GO:0005515	protein binding
0.33	GO:0016776	phosphotransferase activity, phosphate group as acceptor

0.60	GO:0005739	mitochondrion
0.55	GO:0031970	organelle envelope lumen
0.54	GO:0016604	nuclear body
0.53	GO:0009295	nucleoid
0.46	GO:0019866	organelle inner membrane
0.45	GO:0043232	intracellular non-membrane-bounded organelle

0.33

EC:2.7.4

GO:0016776

sp|Q6PBV4|RWDD3_DANRE
RWD domain-containing protein 3
Search

RWDD3

0.97	RWD domain-containing protein 3

0.87	GO:1902073	positive regulation of hypoxia-inducible factor-1alpha signaling pathway
0.85	GO:0033235	positive regulation of protein sumoylation
0.83	GO:0032088	negative regulation of NF-kappaB transcription factor activity

0.36

GO:0005515

protein binding

0.46	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm

sp|Q6PBV6|NHP2_DANRE
H/ACA ribonucleoprotein complex subunit 2-like protein
Search

NHP2

0.87	H/ACA ribonucleoprotein complex subunit 2

0.57	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.51	GO:0031118	rRNA pseudouridine synthesis
0.49	GO:0031120	snRNA pseudouridine synthesis
0.47	GO:0000470	maturation of LSU-rRNA
0.47	GO:0000469	cleavage involved in rRNA processing
0.40	GO:0043043	peptide biosynthetic process
0.39	GO:0044267	cellular protein metabolic process
0.38	GO:0009059	macromolecule biosynthetic process
0.37	GO:0016074	snoRNA metabolic process
0.36	GO:0010833	telomere maintenance via telomere lengthening

0.59	GO:0034513	box H/ACA snoRNA binding
0.57	GO:0070034	telomerase RNA binding
0.37	GO:0034511	U3 snoRNA binding
0.37	GO:0003730	mRNA 3'-UTR binding
0.35	GO:0005515	protein binding

0.69	GO:0005730	nucleolus
0.59	GO:0019013	viral nucleocapsid
0.58	GO:0090661	box H/ACA telomerase RNP complex
0.47	GO:0022625	cytosolic large ribosomal subunit
0.45	GO:1902494	catalytic complex
0.40	GO:0015030	Cajal body
0.38	GO:0000784	nuclear chromosome, telomeric region

tr|Q6PBW3|Q6PBW3_DANRE
Ribosomal protein S14
Search

RPS14

0.62	Ribosomal protein S14

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.54	GO:0030218	erythrocyte differentiation
0.53	GO:0009059	macromolecule biosynthetic process
0.52	GO:0000028	ribosomal small subunit assembly
0.47	GO:0000122	negative regulation of transcription by RNA polymerase II
0.45	GO:0006417	regulation of translation
0.44	GO:0061515	myeloid cell development
0.43	GO:0071695	anatomical structure maturation

0.64	GO:0003735	structural constituent of ribosome
0.51	GO:0048027	mRNA 5'-UTR binding
0.49	GO:0045182	translation regulator activity
0.44	GO:0070181	small ribosomal subunit rRNA binding
0.39	GO:0042289	MHC class II protein binding
0.34	GO:0004683	calmodulin-dependent protein kinase activity
0.34	GO:0005516	calmodulin binding
0.34	GO:0008146	sulfotransferase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.61	GO:0005840	ribosome
0.47	GO:0044445	cytosolic part
0.45	GO:0005730	nucleolus
0.40	GO:0005739	mitochondrion
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.7.11.17

GO:0004683

sp|Q6PBW5|RP65A_DANRE
Retinoid isomerohydrolase
Search

RPE65

0.97	Retinal Mueller cells isomerohydrolase

0.64	GO:0001523	retinoid metabolic process
0.60	GO:1901827	zeaxanthin biosynthetic process
0.60	GO:0034308	primary alcohol metabolic process
0.59	GO:0034754	cellular hormone metabolic process
0.55	GO:0007468	regulation of rhodopsin gene expression
0.55	GO:0050908	detection of light stimulus involved in visual perception
0.54	GO:0071257	cellular response to electrical stimulus
0.54	GO:0001895	retina homeostasis
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0008286	insulin receptor signaling pathway

0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.69	GO:0052885	all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity
0.66	GO:1901612	cardiolipin binding
0.64	GO:0031210	phosphatidylcholine binding
0.64	GO:0001786	phosphatidylserine binding
0.58	GO:0004744	retinal isomerase activity
0.53	GO:0046872	metal ion binding
0.49	GO:0052884	all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity
0.36	GO:0050251	retinol isomerase activity
0.34	GO:0005515	protein binding

0.39	GO:0005783	endoplasmic reticulum
0.37	GO:0005886	plasma membrane
0.37	GO:0044297	cell body
0.37	GO:0031090	organelle membrane
0.33	GO:0005829	cytosol

0.75	EC:1.13.11	GO:0016702
0.69	KEGG:R08388	GO:0052885

tr|Q6PBW8|Q6PBW8_DANRE
Lysophospholipase II
Search

LYPLA2

0.89	Lysophospholipase II

0.67	GO:0002084	protein depalmitoylation
0.47	GO:0042997	negative regulation of Golgi to plasma membrane protein transport

0.67	GO:0008474	palmitoyl-(protein) hydrolase activity
0.59	GO:0045296	cadherin binding
0.46	GO:0052689	carboxylic ester hydrolase activity
0.43	GO:0016298	lipase activity

0.58	GO:0005795	Golgi stack
0.40	GO:0005829	cytosol
0.38	GO:0005739	mitochondrion

0.67	EC:3.1.2.22	GO:0008474
0.46	KEGG:R00630	GO:0052689

tr|Q6PBW9|Q6PBW9_DANRE
Ribulose-phosphate 3-epimerase
Search

RPE

0.42	Ribulose-phosphate 3-epimerase

0.67	GO:0006098	pentose-phosphate shunt
0.60	GO:0005975	carbohydrate metabolic process
0.45	GO:0060271	cilium assembly
0.42	GO:0044282	small molecule catabolic process
0.40	GO:1901575	organic substance catabolic process

0.73	GO:0004750	ribulose-phosphate 3-epimerase activity
0.51	GO:0046872	metal ion binding
0.36	GO:0042803	protein homodimerization activity
0.35	GO:0048029	monosaccharide binding

0.43	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.33	GO:0043231	intracellular membrane-bounded organelle

0.73	EC:5.1.3.1	GO:0004750
0.73	KEGG:R01529	GO:0004750

tr|Q6PBX2|Q6PBX2_DANRE
SAR1a gene homolog 2 (S. cerevisiae)
Search

SAR1B

0.84	Secretion associated Ras related GTPase 1B

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.64	GO:0051668	localization within membrane
0.61	GO:0016050	vesicle organization
0.55	GO:0030299	intestinal cholesterol absorption
0.55	GO:0034622	cellular macromolecular complex assembly
0.54	GO:0061024	membrane organization
0.53	GO:0048703	embryonic viscerocranium morphogenesis
0.52	GO:0035265	organ growth
0.50	GO:0007417	central nervous system development

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0005794	Golgi apparatus
0.70	GO:0005783	endoplasmic reticulum
0.62	GO:0030127	COPII vesicle coat
0.54	GO:0031984	organelle subcompartment

tr|Q6PBX3|Q6PBX3_DANRE
Hairy-related 6
Search

HES1

0.90	LOW QUALITY PROTEIN: transcription factor HES-4

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0006355	regulation of transcription, DNA-templated
0.56	GO:0050767	regulation of neurogenesis
0.56	GO:0007219	Notch signaling pathway
0.56	GO:0021536	diencephalon development
0.54	GO:0009952	anterior/posterior pattern specification
0.54	GO:0043009	chordate embryonic development
0.54	GO:0061106	negative regulation of stomach neuroendocrine cell differentiation
0.54	GO:2000974	negative regulation of pro-B cell differentiation
0.53	GO:0007262	STAT protein import into nucleus

0.68	GO:0046983	protein dimerization activity
0.55	GO:0003677	DNA binding
0.50	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0042826	histone deacetylase binding
0.47	GO:0051087	chaperone binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0042802	identical protein binding
0.40	GO:0008134	transcription factor binding
0.35	GO:0008432	JUN kinase binding
0.34	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome

0.34

EC:3.2.1.23

GO:0004565

sp|Q6PBX5|MTND_DANRE
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase
Search

ADI1

0.74	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase

0.76	GO:0019509	L-methionine salvage from methylthioadenosine
0.52	GO:0055114	oxidation-reduction process
0.35	GO:0051302	regulation of cell division
0.34	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:0010468	regulation of gene expression
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression

0.82	GO:0010309	acireductone dioxygenase [iron(II)-requiring] activity
0.57	GO:0005506	iron ion binding
0.34	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.33	GO:0003676	nucleic acid binding
0.33	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0003700	DNA binding transcription factor activity

0.60	GO:0005634	nucleus
0.48	GO:0005886	plasma membrane
0.48	GO:0005737	cytoplasm
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle

0.82	EC:1.13.11.54	GO:0010309
0.82	KEGG:R07364	GO:0010309

tr|Q6PBX6|Q6PBX6_DANRE
Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
Search

UBE2D3

0.55	Ubiquitin--protein ligase

0.48	GO:0000209	protein polyubiquitination
0.45	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.45	GO:0051865	protein autoubiquitination
0.44	GO:1903955	positive regulation of protein targeting to mitochondrion
0.44	GO:0006513	protein monoubiquitination
0.40	GO:0045676	regulation of R7 cell differentiation
0.40	GO:0048132	female germ-line stem cell asymmetric division
0.40	GO:0016322	neuron remodeling
0.40	GO:0030718	germ-line stem cell population maintenance
0.40	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0061631	ubiquitin conjugating enzyme activity
0.39	GO:0031625	ubiquitin protein ligase binding
0.39	GO:0016874	ligase activity
0.38	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.39	GO:0010008	endosome membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0005886	plasma membrane
0.33	GO:0005654	nucleoplasm
0.33	GO:0000151	ubiquitin ligase complex
0.33	GO:0005829	cytosol
0.32	GO:0043234	protein complex
0.30	GO:0044425	membrane part

0.39

GO:0016874

tr|Q6PBX8|Q6PBX8_DANRE
NADH dehydrogenase (ubiquinone) flavoprotein 2
Search

NDUFV2

0.83	Mitochondrial NADH dehydrogenase flavoprotein 2

0.52	GO:0055114	oxidation-reduction process
0.43	GO:0048738	cardiac muscle tissue development
0.41	GO:0007399	nervous system development
0.40	GO:0006119	oxidative phosphorylation
0.36	GO:0032981	mitochondrial respiratory chain complex I assembly

0.68	GO:0051537	2 iron, 2 sulfur cluster binding
0.53	GO:0016491	oxidoreductase activity
0.52	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.46	GO:0045272	plasma membrane respiratory chain complex I
0.45	GO:0005747	mitochondrial respiratory chain complex I
0.42	GO:0043209	myelin sheath

0.53

GO:0016491

tr|Q6PBX9|Q6PBX9_DANRE
Receptor expression-enhancing protein
Search

REEP5

0.71	Receptor expression-enhancing protein 5

0.39	GO:0050908	detection of light stimulus involved in visual perception
0.34	GO:0032386	regulation of intracellular transport

0.34

GO:0005515

protein binding

0.52	GO:0071782	endoplasmic reticulum tubular network
0.39	GO:0001917	photoreceptor inner segment
0.36	GO:0070062	extracellular exosome
0.35	GO:0044317	rod spherule
0.34	GO:0045177	apical part of cell
0.33	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q6PBY0|Q6PBY0_DANRE
Guanine nucleotide binding protein (G protein), beta 5
Search

GNB5

0.87	guanine nucleotide-binding protein subunit beta-5

0.60	GO:0007165	signal transduction
0.46	GO:1901386	negative regulation of voltage-gated calcium channel activity
0.46	GO:0036269	swimming behavior
0.46	GO:0007634	optokinetic behavior
0.45	GO:0060047	heart contraction
0.40	GO:0043547	positive regulation of GTPase activity
0.36	GO:0006457	protein folding
0.35	GO:0042981	regulation of apoptotic process
0.35	GO:0007018	microtubule-based movement
0.35	GO:0016573	histone acetylation

0.49	GO:0031682	G-protein gamma-subunit binding
0.43	GO:0051087	chaperone binding
0.40	GO:0005096	GTPase activator activity
0.40	GO:0004871	signal transducer activity
0.36	GO:0032794	GTPase activating protein binding
0.35	GO:0051015	actin filament binding
0.35	GO:0003777	microtubule motor activity
0.35	GO:0008017	microtubule binding
0.35	GO:0004402	histone acetyltransferase activity
0.34	GO:0003924	GTPase activity

0.44	GO:0001917	photoreceptor inner segment
0.44	GO:0001750	photoreceptor outer segment
0.43	GO:0043209	myelin sheath
0.39	GO:0005829	cytosol
0.38	GO:0005634	nucleus
0.37	GO:0005886	plasma membrane
0.36	GO:1902773	GTPase activator complex
0.35	GO:1905360	GTPase complex
0.35	GO:0044297	cell body
0.35	GO:0016459	myosin complex

0.35

GO:0004402

sp|Q6PBY1|RS3A_DANRE
40S ribosomal protein S3a
Search

sp|Q6PBY3|EDF1_DANRE
Endothelial differentiation-related factor 1 homolog
Search

EDF1

0.96	Endothelial differentiation-related factor 1 isoform alpha

0.52	GO:0043388	positive regulation of DNA binding
0.42	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:0007275	multicellular organism development
0.37	GO:1902680	positive regulation of RNA biosynthetic process
0.37	GO:0010628	positive regulation of gene expression
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0030154	cell differentiation
0.36	GO:0006351	transcription, DNA-templated
0.34	GO:0003158	endothelium development
0.34	GO:0019216	regulation of lipid metabolic process

0.65	GO:0043565	sequence-specific DNA binding
0.51	GO:0003713	transcription coactivator activity
0.38	GO:0030674	protein binding, bridging
0.38	GO:0005516	calmodulin binding
0.36	GO:0004402	histone acetyltransferase activity
0.34	GO:0008168	methyltransferase activity
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003723	RNA binding

0.49	GO:0005669	transcription factor TFIID complex
0.47	GO:0005730	nucleolus
0.45	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.36

GO:0004402

sp|Q6PBY7|TPC13_DANRE
Trafficking protein particle complex subunit 13
Search

TRAPPC13

0.96	Trafficking protein particle complex subunit 13

0.51

GO:0065009

regulation of molecular function

0.61

GO:0017112

Rab guanyl-nucleotide exchange factor activity

0.52

GO:0005829

cytosol

tr|Q6PBY8|Q6PBY8_DANRE
S-phase kinase-associated protein 1
Search

SKP1

0.92	S-phase kinase-associated protein 1

0.70	GO:0006511	ubiquitin-dependent protein catabolic process
0.53	GO:0016310	phosphorylation
0.44	GO:0010498	proteasomal protein catabolic process
0.42	GO:0016567	protein ubiquitination
0.41	GO:0051457	maintenance of protein location in nucleus
0.39	GO:0016570	histone modification
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0010265	SCF complex assembly
0.36	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.36	GO:0038095	Fc-epsilon receptor signaling pathway

0.55	GO:0016301	kinase activity
0.41	GO:0097602	cullin family protein binding
0.40	GO:0008013	beta-catenin binding
0.39	GO:0019904	protein domain specific binding
0.39	GO:0061630	ubiquitin protein ligase activity
0.37	GO:0004806	triglyceride lipase activity
0.33	GO:0016874	ligase activity

0.50	GO:0031467	Cul7-RING ubiquitin ligase complex
0.48	GO:0019005	SCF ubiquitin ligase complex
0.42	GO:0005829	cytosol
0.41	GO:0005813	centrosome
0.40	GO:0031519	PcG protein complex
0.37	GO:0070062	extracellular exosome
0.36	GO:0005654	nucleoplasm

0.37

EC:3.1.1.3

GO:0004806

tr|Q6PBZ1|Q6PBZ1_DANRE
Ribosomal protein L7a
Search

RPL7A

0.81	Ribosomal protein L7a

0.66	GO:0042254	ribosome biogenesis
0.43	GO:0016072	rRNA metabolic process
0.42	GO:0034470	ncRNA processing
0.40	GO:0043043	peptide biosynthetic process
0.39	GO:0044267	cellular protein metabolic process
0.38	GO:0009059	macromolecule biosynthetic process
0.35	GO:1904401	cellular response to Thyroid stimulating hormone
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription

0.45	GO:0045296	cadherin binding
0.40	GO:0003723	RNA binding
0.33	GO:0003735	structural constituent of ribosome

0.61	GO:0030529	intracellular ribonucleoprotein complex
0.53	GO:0043232	intracellular non-membrane-bounded organelle
0.50	GO:0044444	cytoplasmic part
0.39	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|Q6PBZ5|Q6PBZ5_DANRE
Allograft inflammatory factor 1-like
Search

AIF1L

0.95	Allograft inflammatory factor 1 like

0.53	GO:0071673	positive regulation of smooth muscle cell chemotaxis
0.51	GO:0016601	Rac protein signal transduction
0.51	GO:2000406	positive regulation of T cell migration
0.51	GO:0090026	positive regulation of monocyte chemotaxis
0.51	GO:0071672	negative regulation of smooth muscle cell chemotaxis
0.51	GO:0048661	positive regulation of smooth muscle cell proliferation
0.51	GO:0097178	ruffle assembly
0.50	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.50	GO:0071346	cellular response to interferon-gamma
0.50	GO:0006911	phagocytosis, engulfment

0.76	GO:0051015	actin filament binding
0.67	GO:0005509	calcium ion binding

0.55	GO:0005884	actin filament
0.52	GO:0032587	ruffle membrane
0.51	GO:0001891	phagocytic cup
0.49	GO:0030027	lamellipodium
0.46	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0005925	focal adhesion
0.44	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.39	GO:0043204	perikaryon
0.36	GO:0070062	extracellular exosome

tr|Q6PBZ7|Q6PBZ7_DANRE
Fragile histidine triad gene
Search

FHIT

0.87	Nitrilase and fragile histidine triad fusion protein NitFhit

0.50	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.50	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.41	GO:0006163	purine nucleotide metabolic process
0.36	GO:0015962	diadenosine triphosphate metabolic process
0.36	GO:0034655	nucleobase-containing compound catabolic process
0.36	GO:1901658	glycosyl compound catabolic process
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:0006355	regulation of transcription, DNA-templated
0.35	GO:0006259	DNA metabolic process
0.34	GO:0009116	nucleoside metabolic process

0.52	GO:0047710	bis(5'-adenosyl)-triphosphatase activity
0.47	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0042802	identical protein binding
0.37	GO:0043530	adenosine 5'-monophosphoramidase activity
0.36	GO:0016819	hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides
0.35	GO:1901265	nucleoside phosphate binding
0.34	GO:0036094	small molecule binding
0.34	GO:0017111	nucleoside-triphosphatase activity
0.34	GO:0016151	nickel cation binding
0.33	GO:0016746	transferase activity, transferring acyl groups

0.49	GO:0001650	fibrillar center
0.44	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.52	EC:3.6.1.29	GO:0047710
0.52	KEGG:R00187	GO:0047710

tr|Q6PBZ8|Q6PBZ8_DANRE
Exosc4 protein
Search

EXOSC4

0.73	Exosome component 4

0.74	GO:0071028	nuclear mRNA surveillance
0.73	GO:0045006	DNA deamination
0.71	GO:0071044	histone mRNA catabolic process
0.67	GO:0030307	positive regulation of cell growth
0.65	GO:0000460	maturation of 5.8S rRNA
0.64	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing
0.63	GO:0051607	defense response to virus
0.63	GO:0034475	U4 snRNA 3'-end processing
0.62	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
0.62	GO:0031125	rRNA 3'-end processing

0.69	GO:0017091	AU-rich element binding
0.53	GO:0004527	exonuclease activity
0.38	GO:0004540	ribonuclease activity
0.37	GO:0009022	tRNA nucleotidyltransferase activity
0.37	GO:0005515	protein binding
0.36	GO:0046872	metal ion binding

0.70	GO:0000178	exosome (RNase complex)
0.69	GO:0035327	transcriptionally active chromatin
0.64	GO:0045111	intermediate filament cytoskeleton
0.57	GO:0005829	cytosol
0.55	GO:0005634	nucleus
0.52	GO:0031974	membrane-enclosed lumen
0.38	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.37

EC:2.7.7.56

GO:0009022

tr|Q6PC03|Q6PC03_DANRE
C20orf20 homolog (H. sapiens)
Search

MRGBP

0.90	MRG domain binding protein (Fragment)

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.46	GO:0016573	histone acetylation
0.36	GO:0040008	regulation of growth
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly
0.33	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.33	GO:0006401	RNA catabolic process
0.33	GO:0006397	mRNA processing

0.33	GO:0004535	poly(A)-specific ribonuclease activity
0.33	GO:0005515	protein binding
0.32	GO:0016740	transferase activity
0.32	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.79	GO:0043189	H4/H2A histone acetyltransferase complex
0.40	GO:0043234	protein complex
0.33	GO:0000932	P-body

0.33

EC:3.1.13.4

GO:0004535

tr|Q6PC06|Q6PC06_DANRE
Adenosylhomocysteinase
Search

AHCYL2

0.55	Adenosylhomocysteinase

0.72	GO:0006730	one-carbon metabolic process
0.45	GO:0033353	S-adenosylmethionine cycle
0.40	GO:0009953	dorsal/ventral pattern formation
0.35	GO:0048598	embryonic morphogenesis
0.35	GO:0042045	epithelial fluid transport
0.35	GO:0010765	positive regulation of sodium ion transport
0.35	GO:0038166	angiotensin-activated signaling pathway
0.35	GO:0031440	regulation of mRNA 3'-end processing
0.34	GO:0006611	protein export from nucleus
0.34	GO:0044070	regulation of anion transport

0.80	GO:0004013	adenosylhomocysteinase activity
0.35	GO:0005515	protein binding

0.46	GO:0043005	neuron projection
0.46	GO:0005829	cytosol
0.39	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

0.80

EC:3.3.1.1

GO:0004013

tr|Q6PC07|Q6PC07_DANRE
Purpurin
Search

0.97	Retinol binding protein 4, like

0.86	GO:0034633	retinol transport
0.50	GO:0001654	eye development
0.48	GO:0032526	response to retinoic acid
0.48	GO:0030277	maintenance of gastrointestinal epithelium
0.48	GO:0042572	retinol metabolic process
0.48	GO:0032024	positive regulation of insulin secretion
0.46	GO:0042593	glucose homeostasis
0.43	GO:0019319	hexose biosynthetic process
0.43	GO:0006006	glucose metabolic process
0.37	GO:0060157	urinary bladder development

0.86	GO:0034632	retinol transmembrane transporter activity
0.83	GO:0005501	retinoid binding
0.48	GO:0043178	alcohol binding
0.42	GO:0019842	vitamin binding
0.35	GO:0046982	protein heterodimerization activity

0.45	GO:0005615	extracellular space
0.35	GO:0033165	interphotoreceptor matrix
0.35	GO:1903561	extracellular vesicle
0.34	GO:0043234	protein complex
0.33	GO:0005829	cytosol

tr|Q6PC12|Q6PC12_DANRE
Enolase 1, (Alpha)
Search

ENO1

0.43	Alpha-enolase

0.71	GO:0006096	glycolytic process
0.50	GO:1903297	regulation of hypoxia-induced intrinsic apoptotic signaling pathway
0.50	GO:0010756	positive regulation of plasminogen activation
0.50	GO:0061718	glucose catabolic process to pyruvate
0.50	GO:2001171	positive regulation of ATP biosynthetic process
0.49	GO:0006735	NADH regeneration
0.49	GO:1900038	negative regulation of cellular response to hypoxia
0.48	GO:0045933	positive regulation of muscle contraction
0.48	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.47	GO:0030308	negative regulation of cell growth

0.78	GO:0004634	phosphopyruvate hydratase activity
0.64	GO:0000287	magnesium ion binding
0.48	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0045296	cadherin binding
0.46	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.45	GO:0042803	protein homodimerization activity
0.44	GO:0051020	GTPase binding
0.36	GO:0046982	protein heterodimerization activity
0.35	GO:0003723	RNA binding
0.34	GO:0005212	structural constituent of eye lens

0.77	GO:0000015	phosphopyruvate hydratase complex
0.47	GO:0099738	cell cortex region
0.45	GO:0009986	cell surface
0.39	GO:0005886	plasma membrane
0.37	GO:0043209	myelin sheath
0.36	GO:0019898	extrinsic component of membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0031430	M band
0.34	GO:0030426	growth cone
0.34	GO:0098857	membrane microdomain

0.78

EC:4.2.1.11

GO:0004634

tr|Q6PC13|Q6PC13_DANRE
Prohibitin 2
Search

PHB2

0.88	Prohibitin 2

0.54	GO:0033600	negative regulation of mammary gland epithelial cell proliferation
0.54	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis
0.54	GO:0031536	positive regulation of exit from mitosis
0.54	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway
0.53	GO:0000060	protein import into nucleus, translocation
0.52	GO:1902808	positive regulation of cell cycle G1/S phase transition
0.51	GO:0060744	mammary gland branching involved in thelarche
0.51	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.51	GO:0043433	negative regulation of DNA binding transcription factor activity
0.51	GO:0051091	positive regulation of DNA binding transcription factor activity

0.52	GO:0047485	protein N-terminus binding
0.51	GO:0008022	protein C-terminus binding
0.46	GO:0033218	amide binding
0.35	GO:0030331	estrogen receptor binding

0.53	GO:0016363	nuclear matrix
0.49	GO:0005741	mitochondrial outer membrane
0.48	GO:0009986	cell surface
0.43	GO:0005743	mitochondrial inner membrane
0.42	GO:0043234	protein complex
0.40	GO:0071944	cell periphery
0.38	GO:0030424	axon
0.36	GO:0031982	vesicle
0.36	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space

sp|Q6PC14|RL23_DANRE
60S ribosomal protein L23
Search

RPL23

0.64	Ribosomal protein L23

0.57	GO:0043043	peptide biosynthetic process
0.53	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.47	GO:0072717	cellular response to actinomycin D
0.45	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.45	GO:1901798	positive regulation of signal transduction by p53 class mediator
0.45	GO:1904667	negative regulation of ubiquitin protein ligase activity
0.45	GO:0071157	negative regulation of cell cycle arrest
0.45	GO:0071158	positive regulation of cell cycle arrest

0.61	GO:0003735	structural constituent of ribosome
0.46	GO:1990948	ubiquitin ligase inhibitor activity
0.46	GO:0001223	transcription coactivator binding
0.44	GO:0070180	large ribosomal subunit rRNA binding
0.43	GO:0031625	ubiquitin protein ligase binding

0.58	GO:0005840	ribosome
0.44	GO:0005730	nucleolus
0.42	GO:0044445	cytosolic part
0.40	GO:0005654	nucleoplasm
0.38	GO:0043234	protein complex
0.37	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q6PC19|SSU72_DANRE
RNA polymerase II subunit A C-terminal domain phosphatase SSU72
Search

SSU72

0.86	RNA polymerase II subunit A C-terminal domain phosphatase SSU72

0.68	GO:0006470	protein dephosphorylation
0.66	GO:0006397	mRNA processing
0.48	GO:0043631	RNA polyadenylation
0.47	GO:0031123	RNA 3'-end processing
0.46	GO:0006369	termination of RNA polymerase II transcription
0.45	GO:0006357	regulation of transcription by RNA polymerase II

0.68	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0005515	protein binding

0.58	GO:0005634	nucleus
0.44	GO:0031974	membrane-enclosed lumen
0.41	GO:0005829	cytosol
0.40	GO:0044446	intracellular organelle part
0.39	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.68

EC:3.1.3.16

GO:0004721

tr|Q6PC22|Q6PC22_DANRE
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8
Search

NDUFA8

0.91	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8

0.70	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.57	GO:0032981	mitochondrial respiratory chain complex I assembly

0.51	GO:0032403	protein complex binding
0.33	GO:0008137	NADH dehydrogenase (ubiquinone) activity

0.76	GO:0005747	mitochondrial respiratory chain complex I
0.54	GO:0005758	mitochondrial intermembrane space

0.33

GO:0008137

sp|Q6PC24|YIF1A_DANRE
Protein YIF1A
Search

YIF1A

0.97	Yip1 interacting factor homolog A

0.50

GO:0006888

ER to Golgi vesicle-mediated transport

0.58	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.51	GO:0030173	integral component of Golgi membrane
0.50	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.47	GO:0005789	endoplasmic reticulum membrane

tr|Q6PC28|Q6PC28_DANRE
Secretogranin V
Search

SCG5

0.90	Secretogranin V

0.80	GO:0007218	neuropeptide signaling pathway
0.57	GO:0016486	peptide hormone processing
0.55	GO:0046883	regulation of hormone secretion
0.50	GO:0043086	negative regulation of catalytic activity
0.49	GO:0006886	intracellular protein transport
0.33	GO:0006937	regulation of muscle contraction
0.33	GO:0010952	positive regulation of peptidase activity
0.33	GO:0045861	negative regulation of proteolysis

0.51	GO:0004857	enzyme inhibitor activity
0.50	GO:0051082	unfolded protein binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0016504	peptidase activator activity
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.81	GO:0030141	secretory granule
0.37	GO:0005576	extracellular region
0.36	GO:0031514	motile cilium
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q6PC29|143G1_DANRE
14-3-3 protein gamma-1
Search

YWHAG

0.97	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma

0.51	GO:0048167	regulation of synaptic plasticity
0.50	GO:0045664	regulation of neuron differentiation
0.45	GO:0006605	protein targeting
0.40	GO:0007507	heart development
0.40	GO:0007420	brain development
0.38	GO:0032869	cellular response to insulin stimulus
0.38	GO:0055114	oxidation-reduction process
0.35	GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0006713	glucocorticoid catabolic process

0.77	GO:0019904	protein domain specific binding
0.53	GO:0005159	insulin-like growth factor receptor binding
0.52	GO:0005080	protein kinase C binding
0.47	GO:0042802	identical protein binding
0.42	GO:0004497	monooxygenase activity
0.39	GO:0030971	receptor tyrosine kinase binding
0.36	GO:0003779	actin binding
0.35	GO:0098772	molecular function regulator
0.35	GO:0035259	glucocorticoid receptor binding
0.34	GO:0044325	ion channel binding

0.49	GO:0043209	myelin sheath
0.37	GO:0005622	intracellular
0.37	GO:0031982	vesicle
0.36	GO:0005925	focal adhesion
0.36	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space
0.34	GO:0031090	organelle membrane
0.34	GO:1905369	endopeptidase complex
0.33	GO:0043234	protein complex
0.32	GO:0005886	plasma membrane

0.34

GO:0004298

sp|Q6PC30|CSN5_DANRE
COP9 signalosome complex subunit 5
Search

COPS5

0.85	COP9 constitutive photomorphogenic homolog subunit 5

0.58	GO:1990182	exosomal secretion
0.58	GO:1903894	regulation of IRE1-mediated unfolded protein response
0.58	GO:0006508	proteolysis
0.55	GO:0051091	positive regulation of DNA binding transcription factor activity
0.54	GO:0046328	regulation of JNK cascade
0.53	GO:0043066	negative regulation of apoptotic process
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.50	GO:0051726	regulation of cell cycle
0.49	GO:0070647	protein modification by small protein conjugation or removal
0.36	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c

0.66	GO:0004222	metalloendopeptidase activity
0.60	GO:0035718	macrophage migration inhibitory factor binding
0.52	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.49	GO:0019899	enzyme binding
0.36	GO:0003713	transcription coactivator activity
0.35	GO:0019784	NEDD8-specific protease activity
0.35	GO:0046872	metal ion binding
0.35	GO:0046983	protein dimerization activity
0.34	GO:0003743	translation initiation factor activity

0.76	GO:0008180	COP9 signalosome
0.55	GO:0008021	synaptic vesicle
0.49	GO:0000785	chromatin
0.48	GO:0005829	cytosol
0.48	GO:0005654	nucleoplasm
0.40	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0030054	cell junction
0.34	GO:0005852	eukaryotic translation initiation factor 3 complex
0.34	GO:0005667	transcription factor complex
0.33	GO:0005739	mitochondrion

0.66

GO:0004222

tr|Q6PC33|Q6PC33_DANRE
Calcium/calmodulin-dependent protein kinase IG
Search

CAMK1G

0.97	Calcium/calmodulin-dependent protein kinase IGb

0.63	GO:0006468	protein phosphorylation
0.48	GO:0018210	peptidyl-threonine modification
0.47	GO:0018209	peptidyl-serine modification
0.44	GO:0045475	locomotor rhythm
0.41	GO:0035556	intracellular signal transduction
0.34	GO:0010976	positive regulation of neuron projection development

0.64	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0005516	calmodulin binding

0.56	GO:0005954	calcium- and calmodulin-dependent protein kinase complex
0.45	GO:0012505	endomembrane system
0.40	GO:0005886	plasma membrane
0.36	GO:0043005	neuron projection
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0031984	organelle subcompartment
0.34	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0044444	cytoplasmic part
0.30	GO:0031224	intrinsic component of membrane

0.64

GO:0004674

tr|Q6PC34|Q6PC34_DANRE
Hippocalcin
Search

HPCAL1

0.89	neuron-specific calcium-binding protein hippocalcin

0.49	GO:1901385	regulation of voltage-gated calcium channel activity
0.48	GO:0071277	cellular response to calcium ion
0.47	GO:0048839	inner ear development
0.35	GO:1904010	response to Aroclor 1254
0.35	GO:1901986	response to ketamine
0.35	GO:1904009	cellular response to monosodium glutamate
0.35	GO:1902065	response to L-glutamate
0.35	GO:0031283	negative regulation of guanylate cyclase activity
0.35	GO:0031584	activation of phospholipase D activity
0.35	GO:0071257	cellular response to electrical stimulus

0.70	GO:0005509	calcium ion binding
0.44	GO:0042802	identical protein binding
0.44	GO:0003779	actin binding
0.34	GO:0019900	kinase binding

0.36	GO:0005737	cytoplasm
0.36	GO:0019898	extrinsic component of membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0044327	dendritic spine head
0.35	GO:0032809	neuronal cell body membrane
0.35	GO:0032590	dendrite membrane
0.34	GO:0043204	perikaryon
0.34	GO:0030424	axon

tr|Q6PC36|Q6PC36_DANRE
NECAP endocytosis-associated 1
Search

NECAP1

0.96	NECAP endocytosis-associated protein 1

0.71

GO:0006897

endocytosis

0.57	GO:0030125	clathrin vesicle coat
0.53	GO:0005905	clathrin-coated pit

tr|Q6PC37|Q6PC37_DANRE
Nucleoside diphosphate kinase
Search

0.47	Nucleoside diphosphate kinase B

0.78	GO:0006228	UTP biosynthetic process
0.78	GO:0006183	GTP biosynthetic process
0.75	GO:0046036	CTP metabolic process
0.70	GO:0006165	nucleoside diphosphate phosphorylation
0.46	GO:0050679	positive regulation of epithelial cell proliferation
0.44	GO:0042981	regulation of apoptotic process
0.44	GO:0007595	lactation
0.43	GO:0043388	positive regulation of DNA binding
0.42	GO:0045597	positive regulation of cell differentiation
0.41	GO:0051240	positive regulation of multicellular organismal process

0.79	GO:0004550	nucleoside diphosphate kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.43	GO:0043024	ribosomal small subunit binding
0.40	GO:0042802	identical protein binding
0.40	GO:0019215	intermediate filament binding
0.40	GO:0004536	deoxyribonuclease activity
0.38	GO:0019001	guanyl nucleotide binding

0.47	GO:0001726	ruffle
0.44	GO:0043209	myelin sheath
0.43	GO:0031256	leading edge membrane
0.42	GO:0031253	cell projection membrane
0.42	GO:0030027	lamellipodium
0.40	GO:0005829	cytosol
0.40	GO:0005634	nucleus
0.40	GO:0005925	focal adhesion
0.39	GO:0070062	extracellular exosome
0.39	GO:0005739	mitochondrion

0.79

EC:2.7.4.6

GO:0004550

tr|Q6PC38|Q6PC38_DANRE
Recoverin
Search

RCVRN

0.97	Recoverin a

0.59	GO:0036368	cone photoresponse recovery
0.52	GO:0051924	regulation of calcium ion transport
0.51	GO:0007601	visual perception
0.50	GO:0007602	phototransduction
0.35	GO:0031284	positive regulation of guanylate cyclase activity
0.32	GO:0006468	protein phosphorylation

0.70	GO:0005509	calcium ion binding
0.35	GO:0008048	calcium sensitive guanylate cyclase activator activity
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0004672	protein kinase activity

0.39	GO:0030425	dendrite
0.33	GO:0005829	cytosol

sp|Q6PC40|CD123_DANRE
Cell division cycle protein 123 homolog
Search

CDC123

0.97	Cell division cycle protein 123 homolog

0.67	GO:0007049	cell cycle
0.64	GO:0051301	cell division
0.46	GO:0045786	negative regulation of cell cycle
0.45	GO:0006417	regulation of translation
0.37	GO:1905143	eukaryotic translation initiation factor 2 complex assembly
0.35	GO:0034250	positive regulation of cellular amide metabolic process
0.35	GO:0032270	positive regulation of cellular protein metabolic process
0.35	GO:0010557	positive regulation of macromolecule biosynthetic process
0.35	GO:0031328	positive regulation of cellular biosynthetic process
0.35	GO:0010628	positive regulation of gene expression

0.34	GO:0000287	magnesium ion binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q6PC41|Q6PC41_DANRE
Sap18 protein
Search

SAP18

0.91	histone deacetylase complex subunit SAP18

0.54	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.52	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.50	GO:0043065	positive regulation of apoptotic process
0.45	GO:0008380	RNA splicing
0.43	GO:0006397	mRNA processing
0.40	GO:0006325	chromatin organization
0.40	GO:1903507	negative regulation of nucleic acid-templated transcription
0.40	GO:0006351	transcription, DNA-templated
0.39	GO:0006355	regulation of transcription, DNA-templated
0.39	GO:0045814	negative regulation of gene expression, epigenetic

0.40	GO:0005515	protein binding
0.39	GO:0003714	transcription corepressor activity
0.39	GO:0004407	histone deacetylase activity
0.39	GO:0003723	RNA binding
0.38	GO:0004565	beta-galactosidase activity

0.78	GO:0016604	nuclear body
0.67	GO:0005829	cytosol
0.58	GO:0061574	ASAP complex
0.51	GO:0035145	exon-exon junction complex
0.43	GO:0000118	histone deacetylase complex
0.38	GO:0005667	transcription factor complex
0.30	GO:0031224	intrinsic component of membrane

0.39

GO:0004407

tr|Q6PC43|Q6PC43_DANRE
ADP-ribosylation factor-like 3, like 2
Search

ARL3

0.92	ADP ribosylation factor like GTPase 3

0.53	GO:0042461	photoreceptor cell development
0.52	GO:0000281	mitotic cytokinesis
0.52	GO:0001822	kidney development
0.52	GO:0060271	cilium assembly
0.51	GO:0042073	intraciliary transport
0.51	GO:0007224	smoothened signaling pathway
0.50	GO:0006892	post-Golgi vesicle-mediated transport
0.50	GO:0007264	small GTPase mediated signal transduction
0.47	GO:0048841	regulation of axon extension involved in axon guidance
0.46	GO:0071632	optomotor response

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0008017	microtubule binding
0.46	GO:0003924	GTPase activity
0.34	GO:0046872	metal ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.54	GO:0032391	photoreceptor connecting cilium
0.53	GO:0005881	cytoplasmic microtubule
0.53	GO:0030496	midbody
0.52	GO:0005876	spindle microtubule
0.51	GO:0005813	centrosome
0.50	GO:0036064	ciliary basal body
0.50	GO:0005930	axoneme
0.48	GO:0005794	Golgi apparatus
0.44	GO:0005634	nucleus
0.39	GO:0098588	bounding membrane of organelle

tr|Q6PC44|Q6PC44_DANRE
Calbindin 2, like
Search

CALB2

0.94	Testicular secretory protein Li 8

0.58	GO:0055074	calcium ion homeostasis
0.49	GO:0072027	connecting tubule development
0.49	GO:0072503	cellular divalent inorganic cation homeostasis
0.48	GO:0072221	metanephric distal convoluted tubule development
0.48	GO:0035502	metanephric part of ureteric bud development
0.48	GO:0072205	metanephric collecting duct development
0.48	GO:0007614	short-term memory
0.47	GO:1900271	regulation of long-term synaptic potentiation
0.47	GO:0007616	long-term memory
0.47	GO:0010842	retina layer formation

0.70	GO:0005509	calcium ion binding
0.40	GO:0008270	zinc ion binding
0.39	GO:0005499	vitamin D binding
0.33	GO:0005515	protein binding

0.51	GO:0005829	cytosol
0.50	GO:0043005	neuron projection
0.50	GO:0005921	gap junction
0.49	GO:0045202	synapse
0.46	GO:0120038	plasma membrane bounded cell projection part
0.46	GO:0043025	neuronal cell body
0.44	GO:0005634	nucleus
0.35	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q6PC45|MED30_DANRE
Mediator of RNA polymerase II transcription subunit 30
Search

MED30

0.96	Mediator of RNA polymerase II transcription subunit 30

0.84	GO:0030521	androgen receptor signaling pathway
0.77	GO:0019827	stem cell population maintenance
0.76	GO:0006367	transcription initiation from RNA polymerase II promoter
0.70	GO:0045893	positive regulation of transcription, DNA-templated
0.67	GO:0006357	regulation of transcription by RNA polymerase II
0.43	GO:0016567	protein ubiquitination
0.42	GO:0006882	cellular zinc ion homeostasis
0.41	GO:0071577	zinc II ion transmembrane transport
0.35	GO:0006886	intracellular protein transport

0.85	GO:0046966	thyroid hormone receptor binding
0.75	GO:0001104	RNA polymerase II transcription cofactor activity
0.62	GO:0004872	receptor activity
0.44	GO:0061630	ubiquitin protein ligase activity
0.41	GO:0042809	vitamin D receptor binding
0.41	GO:0005385	zinc ion transmembrane transporter activity
0.40	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.38	GO:0003690	double-stranded DNA binding

0.73	GO:0016592	mediator complex
0.44	GO:0000151	ubiquitin ligase complex
0.30	GO:0031224	intrinsic component of membrane

tr|Q6PC46|Q6PC46_DANRE
Zgc:73111
Search

WDR83OS

0.97	WD repeat domain 83 opposite strand

0.37	GO:0006013	mannose metabolic process
0.34	GO:0006915	apoptotic process
0.34	GO:0042981	regulation of apoptotic process
0.33	GO:0006517	protein deglycosylation
0.33	GO:0006508	proteolysis

0.36	GO:0004559	alpha-mannosidase activity
0.34	GO:0030246	carbohydrate binding
0.34	GO:0004197	cysteine-type endopeptidase activity
0.33	GO:0046872	metal ion binding

0.30

GO:0031224

intrinsic component of membrane

0.36

EC:3.2.1.24

GO:0004559

tr|Q6PC51|Q6PC51_DANRE
Gadd45b protein
Search

GADD45B

0.96	Growth arrest and DNA damage inducible gamma

0.73	GO:0051726	regulation of cell cycle
0.62	GO:0006950	response to stress
0.57	GO:0000185	activation of MAPKKK activity
0.55	GO:1900745	positive regulation of p38MAPK cascade
0.52	GO:0046330	positive regulation of JNK cascade
0.51	GO:0000186	activation of MAPKK activity
0.50	GO:0043065	positive regulation of apoptotic process
0.50	GO:0006469	negative regulation of protein kinase activity
0.45	GO:0001756	somitogenesis
0.44	GO:0051597	response to methylmercury

0.34

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle

tr|Q6PC53|Q6PC53_DANRE
Peptidyl-prolyl cis-trans isomerase
Search

0.49	Peptidyl-prolyl cis-trans isomerase A

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.69	GO:0006457	protein folding
0.39	GO:0010759	positive regulation of macrophage chemotaxis
0.39	GO:0050918	positive chemotaxis
0.38	GO:0060326	cell chemotaxis
0.37	GO:0001666	response to hypoxia

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.39	GO:0042056	chemoattractant activity
0.38	GO:0008009	chemokine activity

0.33	GO:0005829	cytosol
0.33	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.72

GO:0003755

sp|Q6PC54|SN25B_DANRE
Synaptosomal-associated protein 25-B
Search

SNAP25

0.78	Synaptosomal-associated protein 25-B

0.85	GO:1990926	short-term synaptic potentiation
0.84	GO:0099590	neurotransmitter receptor internalization
0.84	GO:0098881	exocytic insertion of neurotransmitter receptor to plasma membrane
0.83	GO:0031915	positive regulation of synaptic plasticity
0.83	GO:0098969	neurotransmitter receptor transport to postsynaptic membrane
0.79	GO:0060291	long-term synaptic potentiation
0.78	GO:0099643	signal release from synapse
0.78	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.78	GO:0007626	locomotory behavior
0.77	GO:0008306	associative learning

0.85	GO:0017075	syntaxin-1 binding
0.57	GO:0005484	SNAP receptor activity

0.86	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
0.80	GO:0031083	BLOC-1 complex
0.78	GO:0042734	presynaptic membrane
0.75	GO:0043209	myelin sheath
0.74	GO:0008021	synaptic vesicle
0.73	GO:0043005	neuron projection
0.72	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.72	GO:0005802	trans-Golgi network
0.72	GO:0036477	somatodendritic compartment
0.72	GO:0048471	perinuclear region of cytoplasm

sp|Q6PC55|GID8_DANRE
Glucose-induced degradation protein 8 homolog
Search

0.95	Glucose-induced degradation protein 8

0.34

GO:0055085

transmembrane transport

0.36

GO:0005515

protein binding

0.73	GO:0030054	cell junction
0.68	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|Q6PC57|Q6PC57_DANRE
Paqr3a protein
Search

PAQR3

0.96	Progestin and adipoQ receptor family member IIIb

0.57	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.55	GO:0034067	protein localization to Golgi apparatus
0.55	GO:0010977	negative regulation of neuron projection development
0.55	GO:0043407	negative regulation of MAP kinase activity
0.34	GO:0000165	MAPK cascade
0.33	GO:0006457	protein folding

0.42	GO:0004872	receptor activity
0.33	GO:0005515	protein binding

0.49	GO:0005794	Golgi apparatus
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

tr|Q6PC58|Q6PC58_DANRE
Ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)
Search

0.96	Ubiquitin-conjugating enzyme E2 D4

0.58	GO:0070936	protein K48-linked ubiquitination
0.55	GO:1902916	positive regulation of protein polyubiquitination
0.49	GO:0035519	protein K29-linked ubiquitination
0.49	GO:0044314	protein K27-linked ubiquitination
0.48	GO:0085020	protein K6-linked ubiquitination
0.48	GO:0006511	ubiquitin-dependent protein catabolic process
0.47	GO:0070979	protein K11-linked ubiquitination
0.47	GO:0070534	protein K63-linked ubiquitination
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0035666	TRIF-dependent toll-like receptor signaling pathway

0.59	GO:0061631	ubiquitin conjugating enzyme activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.33	GO:0016874	ligase activity

0.49	GO:0000151	ubiquitin ligase complex
0.42	GO:0043234	protein complex
0.38	GO:0005737	cytoplasm
0.33	GO:0005654	nucleoplasm

0.33

GO:0016874

sp|Q6PC60|H2B3_DANRE
Histone H2B 3
Search

sp|Q6PC62|SPG21_DANRE
Maspardin
Search

SPG21

0.91	Spastic paraplegia 21, maspardin (Autosomal recessive, Mast syndrome)

0.39

GO:0050851

antigen receptor-mediated signaling pathway

0.76	GO:0042609	CD4 receptor binding
0.35	GO:0016787	hydrolase activity

0.80	GO:0030140	trans-Golgi network transport vesicle
0.67	GO:0005829	cytosol
0.53	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0010008	endosome membrane

0.35

GO:0016787

tr|Q6PC63|Q6PC63_DANRE
Lin-7 homolog A (C. elegans)
Search

LIN7A

0.96	Lin-7 homolog A, crumbs cell polarity complex component

0.82	GO:0099643	signal release from synapse
0.82	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.76	GO:0006836	neurotransmitter transport
0.76	GO:0006887	exocytosis
0.75	GO:0048489	synaptic vesicle transport
0.74	GO:0048839	inner ear development
0.72	GO:0001505	regulation of neurotransmitter levels
0.64	GO:0015031	protein transport
0.63	GO:1903361	protein localization to basolateral plasma membrane
0.61	GO:0045199	maintenance of epithelial cell apical/basal polarity

0.86	GO:0097016	L27 domain binding
0.47	GO:0008092	cytoskeletal protein binding

0.85	GO:0097025	MPP7-DLG1-LIN7 complex
0.83	GO:0016323	basolateral plasma membrane
0.79	GO:0098793	presynapse
0.60	GO:0005911	cell-cell junction
0.44	GO:0005622	intracellular

sp|Q6PC64|ELOV6_DANRE
Elongation of very long chain fatty acids protein 6
Search

ELOVL6

0.55	Elongation of very long chain fatty acids protein 6

0.83	GO:0019367	fatty acid elongation, saturated fatty acid
0.82	GO:0042761	very long-chain fatty acid biosynthetic process
0.72	GO:0034625	fatty acid elongation, monounsaturated fatty acid
0.72	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.68	GO:0006636	unsaturated fatty acid biosynthetic process
0.55	GO:0042759	long-chain fatty acid biosynthetic process
0.49	GO:0034626	fatty acid elongation, polyunsaturated fatty acid
0.47	GO:0030148	sphingolipid biosynthetic process
0.35	GO:0045540	regulation of cholesterol biosynthetic process

0.83	GO:0009922	fatty acid elongase activity
0.82	GO:0102756	very-long-chain 3-ketoacyl-CoA synthase activity
0.82	GO:0102338	3-oxo-lignoceronyl-CoA synthase activity
0.82	GO:0102336	3-oxo-arachidoyl-CoA synthase activity
0.82	GO:0102337	3-oxo-cerotoyl-CoA synthase activity
0.33	GO:0005515	protein binding

0.68	GO:0005783	endoplasmic reticulum
0.62	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.59	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.82

EC:2.3.1.199

GO:0102338

sp|Q6PC69|RL10A_DANRE
60S ribosomal protein L10a
Search

0.53	Ribosomal protein (Fragment)

0.58	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.43	GO:0042273	ribosomal large subunit biogenesis
0.41	GO:0016072	rRNA metabolic process
0.35	GO:0045471	response to ethanol

0.61	GO:0003735	structural constituent of ribosome
0.57	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.67	GO:0015934	large ribosomal subunit
0.49	GO:0022626	cytosolic ribosome
0.48	GO:0042788	polysomal ribosome
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

tr|Q6PC71|Q6PC71_DANRE
Rho family GTPase 3a
Search

RND3

0.97	Rho-related GTP-binding protein RhoE

0.76	GO:0007264	small GTPase mediated signal transduction
0.35	GO:0048672	positive regulation of collateral sprouting
0.34	GO:0030036	actin cytoskeleton organization
0.34	GO:0007155	cell adhesion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0012505	endomembrane system
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q6PC72|Q6PC72_DANRE
Calcium and integrin binding family member 2
Search

CIB2

0.93	DNA-dependent protein kinase catalytic subunit-interacting protein 2

0.67	GO:0007229	integrin-mediated signaling pathway
0.52	GO:0071318	cellular response to ATP
0.49	GO:0045494	photoreceptor cell maintenance
0.49	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.42	GO:0007638	mechanosensory behavior
0.42	GO:0048884	neuromast development
0.41	GO:0043010	camera-type eye development
0.35	GO:0016310	phosphorylation
0.32	GO:0036211	protein modification process
0.32	GO:0044267	cellular protein metabolic process

0.70	GO:0005509	calcium ion binding
0.48	GO:0005178	integrin binding
0.47	GO:0042803	protein homodimerization activity
0.45	GO:0000287	magnesium ion binding
0.35	GO:0016301	kinase activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.53	GO:0032437	cuticular plate
0.50	GO:0032420	stereocilium
0.50	GO:0005927	muscle tendon junction
0.50	GO:0001917	photoreceptor inner segment
0.49	GO:0001750	photoreceptor outer segment
0.49	GO:0042383	sarcolemma
0.49	GO:0031594	neuromuscular junction
0.36	GO:0072562	blood microparticle

0.33

EC:2.7.1

GO:0016773

tr|Q6PC73|Q6PC73_DANRE
Growth factor receptor-bound protein 2
Search

GRB2

0.97	Growth factor receptor-bound protein 2

0.83	GO:0007265	Ras protein signal transduction
0.57	GO:0008286	insulin receptor signaling pathway
0.56	GO:0031623	receptor internalization
0.56	GO:0071479	cellular response to ionizing radiation
0.55	GO:0042770	signal transduction in response to DNA damage
0.55	GO:2000379	positive regulation of reactive oxygen species metabolic process
0.55	GO:0060670	branching involved in labyrinthine layer morphogenesis
0.53	GO:0030838	positive regulation of actin filament polymerization
0.52	GO:0043408	regulation of MAPK cascade
0.51	GO:0009967	positive regulation of signal transduction

0.59	GO:0043560	insulin receptor substrate binding
0.59	GO:0005168	neurotrophin TRKA receptor binding
0.58	GO:0005154	epidermal growth factor receptor binding
0.56	GO:0001784	phosphotyrosine residue binding
0.56	GO:0046875	ephrin receptor binding
0.56	GO:0005070	SH3/SH2 adaptor activity
0.55	GO:0019903	protein phosphatase binding
0.53	GO:0017124	SH3 domain binding
0.52	GO:0019901	protein kinase binding
0.50	GO:0042802	identical protein binding

0.59	GO:0070436	Grb2-EGFR complex
0.54	GO:0008180	COP9 signalosome
0.52	GO:0005768	endosome
0.51	GO:0005911	cell-cell junction
0.51	GO:0012506	vesicle membrane
0.50	GO:0005730	nucleolus
0.49	GO:0005654	nucleoplasm
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.39	GO:0005794	Golgi apparatus
0.36	GO:0070062	extracellular exosome

0.46	EC:2.7.10.2	GO:0004715
0.35	KEGG:R04545	GO:0046934

tr|Q6PC77|Q6PC77_DANRE
ATP synthase subunit d, mitochondrial
Search

ATP5H

0.75	ATP synthase subunit d, mitochondrial

0.68	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.68	GO:0006754	ATP biosynthetic process
0.47	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.34	GO:0042407	cristae formation
0.34	GO:0006839	mitochondrial transport
0.33	GO:0046907	intracellular transport

0.61	GO:0015078	hydrogen ion transmembrane transporter activity
0.48	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.47	GO:0019829	cation-transporting ATPase activity

0.76	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.56	GO:0045265	proton-transporting ATP synthase, stator stalk
0.46	GO:0043209	myelin sheath
0.43	GO:0005654	nucleoplasm
0.36	GO:0070062	extracellular exosome

sp|Q6PC78|RN185_DANRE
E3 ubiquitin-protein ligase RNF185
Search

RNF185

0.97	Ring finger protein 185 (Predicted)

0.51	GO:0030433	ubiquitin-dependent ERAD pathway
0.49	GO:0071712	ER-associated misfolded protein catabolic process
0.47	GO:0051865	protein autoubiquitination
0.47	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.39	GO:0006914	autophagy
0.35	GO:1904380	endoplasmic reticulum mannose trimming
0.35	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.35	GO:0010977	negative regulation of neuron projection development
0.34	GO:0046856	phosphatidylinositol dephosphorylation
0.32	GO:0006468	protein phosphorylation

0.54	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway
0.53	GO:0044390	ubiquitin-like protein conjugating enzyme binding
0.52	GO:0016874	ligase activity
0.36	GO:0046872	metal ion binding
0.35	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0036513	Derlin-1 retrotranslocation complex
0.39	GO:0005741	mitochondrial outer membrane
0.35	GO:0044322	endoplasmic reticulum quality control compartment
0.35	GO:0043198	dendritic shaft
0.35	GO:0030426	growth cone
0.34	GO:0001726	ruffle
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.52

GO:0016874

tr|Q6PC80|Q6PC80_DANRE
Ribosomal protein S5
Search

RPS5

0.45	Palmitoyl-protein thioesterase 2

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.45	GO:0006450	regulation of translational fidelity
0.45	GO:0000028	ribosomal small subunit assembly
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.59	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.70	GO:0015935	small ribosomal subunit
0.49	GO:0022626	cytosolic ribosome
0.38	GO:0000228	nuclear chromosome
0.38	GO:0005730	nucleolus
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0031012	extracellular matrix
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

tr|Q6PC81|Q6PC81_DANRE
Desumoylating isopeptidase 1a
Search

DESI1

0.96	Desumoylating isopeptidase 1

0.44

GO:0006508

proteolysis

0.69	GO:0042802	identical protein binding
0.45	GO:0008233	peptidase activity

0.45	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm

0.45

GO:0008233

tr|Q6PC89|Q6PC89_DANRE
Enolase 1b, (alpha)
Search

0.74	Alpha-enolase

0.71	GO:0006096	glycolytic process
0.46	GO:1903297	regulation of hypoxia-induced intrinsic apoptotic signaling pathway
0.46	GO:0010756	positive regulation of plasminogen activation
0.46	GO:0061718	glucose catabolic process to pyruvate
0.46	GO:2001171	positive regulation of ATP biosynthetic process
0.46	GO:0006735	NADH regeneration
0.46	GO:1900038	negative regulation of cellular response to hypoxia
0.45	GO:0045933	positive regulation of muscle contraction
0.44	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.44	GO:0030308	negative regulation of cell growth

0.78	GO:0004634	phosphopyruvate hydratase activity
0.64	GO:0000287	magnesium ion binding
0.44	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.44	GO:0045296	cadherin binding
0.43	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.42	GO:0042803	protein homodimerization activity
0.42	GO:0051020	GTPase binding
0.37	GO:0046982	protein heterodimerization activity
0.35	GO:0003723	RNA binding
0.35	GO:0005212	structural constituent of eye lens

0.77	GO:0000015	phosphopyruvate hydratase complex
0.44	GO:0099738	cell cortex region
0.42	GO:0009986	cell surface
0.38	GO:0043209	myelin sheath
0.38	GO:0005886	plasma membrane
0.37	GO:0019898	extrinsic component of membrane
0.34	GO:0030426	growth cone
0.34	GO:0070062	extracellular exosome
0.34	GO:0098857	membrane microdomain
0.34	GO:0044456	synapse part

0.78

EC:4.2.1.11

GO:0004634

tr|Q6PC90|Q6PC90_DANRE
40S ribosomal protein S12
Search

RPS12

0.68	40S ribosomal protein S12

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0010243	response to organonitrogen compound
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0032947	protein complex scaffold activity
0.33	GO:0003723	RNA binding
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.33	GO:0003779	actin binding
0.32	GO:0016301	kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.48	GO:0044445	cytosolic part
0.43	GO:0005794	Golgi apparatus
0.42	GO:0044446	intracellular organelle part
0.34	GO:0005923	bicellular tight junction
0.33	GO:0043233	organelle lumen
0.33	GO:0015629	actin cytoskeleton
0.33	GO:0005634	nucleus
0.32	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q6PC91|BT3L4_DANRE
Transcription factor BTF3 homolog 4
Search

BTF3L4

0.78	Transcription factor BTF3

0.57

GO:0034968

histone lysine methylation

0.57	GO:0018024	histone-lysine N-methyltransferase activity
0.56	GO:0003682	chromatin binding
0.44	GO:0005515	protein binding
0.44	GO:0003677	DNA binding
0.43	GO:0046872	metal ion binding

0.47	GO:0005634	nucleus
0.45	GO:0005829	cytosol

0.57

EC:2.1.1.43

GO:0018024

tr|Q6PC92|Q6PC92_DANRE
ADP-ribosylation factor-like 3, like 1
Search

0.93	ADP ribosylation factor like GTPase 3

0.52	GO:0048699	generation of neurons
0.51	GO:0000281	mitotic cytokinesis
0.51	GO:0001822	kidney development
0.51	GO:0060271	cilium assembly
0.50	GO:0042073	intraciliary transport
0.50	GO:0007224	smoothened signaling pathway
0.49	GO:0006892	post-Golgi vesicle-mediated transport
0.49	GO:0007264	small GTPase mediated signal transduction
0.48	GO:0048468	cell development
0.46	GO:0071632	optomotor response

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0008017	microtubule binding
0.45	GO:0003924	GTPase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0016757	transferase activity, transferring glycosyl groups
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.53	GO:0032391	photoreceptor connecting cilium
0.52	GO:0005881	cytoplasmic microtubule
0.52	GO:0030496	midbody
0.51	GO:0005876	spindle microtubule
0.50	GO:0005813	centrosome
0.49	GO:0036064	ciliary basal body
0.49	GO:0005930	axoneme
0.47	GO:0005794	Golgi apparatus
0.43	GO:0005634	nucleus
0.39	GO:0098588	bounding membrane of organelle

0.33

GO:0016757

sp|Q6PC93|NMNA2_DANRE
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2
Search

NMNAT2

0.97	Nicotinamide mononucleotide adenylyltransferase 2

0.51	GO:0019355	nicotinamide nucleotide biosynthetic process from aspartate
0.48	GO:0009435	NAD biosynthetic process
0.37	GO:0009611	response to wounding
0.32	GO:0045454	cell redox homeostasis

0.59	GO:0016779	nucleotidyltransferase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008144	drug binding
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding

0.53	GO:0005770	late endosome
0.53	GO:0005802	trans-Golgi network
0.51	GO:0045202	synapse
0.34	GO:0005739	mitochondrion
0.34	GO:0000139	Golgi membrane
0.33	GO:0030991	intraciliary transport particle A
0.30	GO:0031224	intrinsic component of membrane

0.59

EC:2.7.7

GO:0016779

tr|Q6PC95|Q6PC95_DANRE
Tubulin alpha chain
Search

TUBA4A

0.53	Tubulin alpha chain

0.71	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0002576	platelet degranulation
0.34	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle

0.76	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0019901	protein kinase binding

0.73	GO:0005874	microtubule
0.47	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus

tr|Q6PCA5|Q6PCA5_DANRE
SIX homeobox 3a
Search

SIX3

0.93	SIX homeobox 3

0.79	GO:0001654	eye development
0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.67	GO:0007420	brain development
0.56	GO:0006366	transcription by RNA polymerase II
0.54	GO:0045893	positive regulation of transcription, DNA-templated
0.52	GO:0048562	embryonic organ morphogenesis
0.52	GO:0090596	sensory organ morphogenesis
0.51	GO:0097402	neuroblast migration
0.51	GO:0021631	optic nerve morphogenesis
0.51	GO:1990086	lens fiber cell apoptotic process

0.73	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.55	GO:0003677	DNA binding
0.50	GO:0001222	transcription corepressor binding
0.48	GO:0042826	histone deacetylase binding
0.46	GO:0003713	transcription coactivator activity
0.45	GO:0001067	regulatory region nucleic acid binding
0.38	GO:0005102	receptor binding

0.61

GO:0005634

nucleus

tr|Q6PCR4|Q6PCR4_DANRE
RAN-binding protein 3b
Search

RANBP3

0.92	RAN binding protein 3

0.69	GO:0046907	intracellular transport
0.46	GO:0046604	positive regulation of mitotic centrosome separation
0.44	GO:0000082	G1/S transition of mitotic cell cycle
0.43	GO:0006606	protein import into nucleus
0.43	GO:0007051	spindle organization
0.42	GO:0043547	positive regulation of GTPase activity
0.42	GO:0006405	RNA export from nucleus
0.41	GO:0006511	ubiquitin-dependent protein catabolic process

0.47	GO:0070412	R-SMAD binding
0.43	GO:0008536	Ran GTPase binding
0.42	GO:0005096	GTPase activator activity

0.45	GO:0005622	intracellular
0.41	GO:0031974	membrane-enclosed lumen
0.39	GO:0044422	organelle part
0.39	GO:0043227	membrane-bounded organelle
0.38	GO:0043228	non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

sp|Q6PCR6|ZFR_DANRE
Zinc finger RNA-binding protein
Search

ZFR

0.91	LOW QUALITY PROTEIN: zinc finger RNA-binding protein-like

0.40	GO:0007275	multicellular organism development
0.34	GO:0006955	immune response

0.62	GO:0008270	zinc ion binding
0.50	GO:0003676	nucleic acid binding
0.34	GO:0005515	protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016740	transferase activity

0.38	GO:0005634	nucleus
0.37	GO:0005694	chromosome
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016740

sp|Q6PCR7|EIF3A_DANRE
Eukaryotic translation initiation factor 3 subunit A
Search

EIF3A

0.69	Eukaryotic translation initiation factor 3 subunit A

0.73	GO:0002183	cytoplasmic translational initiation
0.70	GO:0006446	regulation of translational initiation
0.68	GO:0022618	ribonucleoprotein complex assembly
0.56	GO:0075525	viral translational termination-reinitiation
0.55	GO:0075522	IRES-dependent viral translational initiation
0.39	GO:0070373	negative regulation of ERK1 and ERK2 cascade

0.72	GO:0003743	translation initiation factor activity
0.45	GO:0003729	mRNA binding
0.39	GO:0030971	receptor tyrosine kinase binding
0.33	GO:0005198	structural molecule activity

0.76	GO:0005852	eukaryotic translation initiation factor 3 complex
0.71	GO:0016282	eukaryotic 43S preinitiation complex
0.71	GO:0033290	eukaryotic 48S preinitiation complex
0.49	GO:0043614	multi-eIF complex
0.48	GO:0005730	nucleolus
0.46	GO:0005829	cytosol
0.37	GO:0005874	microtubule
0.34	GO:0005815	microtubule organizing center
0.30	GO:0016020	membrane

sp|Q6PCS4|RHG29_DANRE
Rho GTPase-activating protein 29
Search

0.96	Rho GTPase-activating protein 29

0.72	GO:0043547	positive regulation of GTPase activity
0.60	GO:0035556	intracellular signal transduction

0.73	GO:0005096	GTPase activator activity
0.48	GO:0046872	metal ion binding
0.40	GO:0030165	PDZ domain binding

0.44

GO:0005622

intracellular

sp|Q6PCS6|MTFP1_DANRE
Mitochondrial fission process protein 1
Search

MTFP1

0.97	Mitochondrial fission process protein 1

0.77	GO:0000266	mitochondrial fission
0.47	GO:0014850	response to muscle activity
0.44	GO:0006915	apoptotic process
0.37	GO:0007006	mitochondrial membrane organization

0.57	GO:0005739	mitochondrion
0.55	GO:0019866	organelle inner membrane
0.30	GO:0044425	membrane part

tr|Q6PCS7|Q6PCS7_DANRE
Protein kinase, AMP-activated, gamma 1 non-catalytic subunit
Search

PRKAG1

0.96	5'-AMP-activated protein kinase subunit gamma-1

0.55	GO:0016310	phosphorylation
0.50	GO:0010604	positive regulation of macromolecule metabolic process
0.48	GO:0051170	nuclear import
0.45	GO:0006110	regulation of glycolytic process
0.44	GO:0036211	protein modification process
0.43	GO:0010799	regulation of peptidyl-threonine phosphorylation
0.43	GO:0019217	regulation of fatty acid metabolic process
0.42	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.42	GO:0033674	positive regulation of kinase activity
0.42	GO:0044267	cellular protein metabolic process

0.57	GO:0016301	kinase activity
0.53	GO:0019901	protein kinase binding
0.45	GO:0008607	phosphorylase kinase regulator activity
0.44	GO:0008603	cAMP-dependent protein kinase regulator activity
0.44	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.44	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.44	GO:0043531	ADP binding
0.43	GO:0140096	catalytic activity, acting on a protein
0.43	GO:0030295	protein kinase activator activity
0.40	GO:0016208	AMP binding

0.47	GO:0031588	nucleotide-activated protein kinase complex
0.44	GO:0005634	nucleus
0.38	GO:0070013	intracellular organelle lumen
0.38	GO:0034708	methyltransferase complex
0.36	GO:0070062	extracellular exosome
0.36	GO:0044446	intracellular organelle part
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.45

EC:2.7.1

GO:0008607

sp|Q6PD82|TM129_DANRE
E3 ubiquitin-protein ligase TM129
Search

TMEM129

0.95	Transmembrane protein 129

0.71	GO:0016567	protein ubiquitination
0.59	GO:1903513	endoplasmic reticulum to cytosol transport
0.59	GO:0032527	protein exit from endoplasmic reticulum
0.56	GO:0030433	ubiquitin-dependent ERAD pathway

0.75

GO:0061630

ubiquitin protein ligase activity

0.50	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

sp|Q6PD83|BZW1A_DANRE
Basic leucine zipper and W2 domain-containing protein 1-A
Search

BZW1

0.91	Basic leucine zipper and W2 domain-containing protein 1-A

0.44	GO:0006351	transcription, DNA-templated
0.44	GO:2001141	regulation of RNA biosynthetic process
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.37	GO:0022900	electron transport chain

0.76	GO:0045296	cadherin binding
0.40	GO:0051537	2 iron, 2 sulfur cluster binding
0.39	GO:0050660	flavin adenine dinucleotide binding
0.38	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.38	GO:0009055	electron transfer activity
0.37	GO:0003723	RNA binding
0.36	GO:0046872	metal ion binding

0.47	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.38

EC:1.1

GO:0016614

tr|Q6PD99|Q6PD99_DANRE
MARCKS-like 1
Search

0.89	Myristoylated alanine-rich protein kinase C substrate a

0.42	GO:0008284	positive regulation of cell proliferation
0.42	GO:0051764	actin crosslink formation
0.41	GO:0051017	actin filament bundle assembly
0.40	GO:0051260	protein homooligomerization
0.40	GO:0010842	retina layer formation
0.39	GO:0035914	skeletal muscle cell differentiation
0.39	GO:0060541	respiratory system development
0.39	GO:0007420	brain development
0.38	GO:0016310	phosphorylation
0.34	GO:0031584	activation of phospholipase D activity

0.77	GO:0005516	calmodulin binding
0.42	GO:0003779	actin binding
0.42	GO:0005080	protein kinase C binding
0.40	GO:0032403	protein complex binding
0.39	GO:0042802	identical protein binding
0.39	GO:0016301	kinase activity
0.34	GO:0001786	phosphatidylserine binding
0.33	GO:0008995	ribonuclease E activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0016428	tRNA (cytosine-5-)-methyltransferase activity

0.43	GO:0042585	germinal vesicle
0.41	GO:0032432	actin filament bundle
0.40	GO:0005813	centrosome
0.40	GO:0005938	cell cortex
0.38	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.34	GO:0005925	focal adhesion
0.34	GO:0044307	dendritic branch
0.34	GO:0032059	bleb
0.34	GO:0001520	outer dense fiber

0.33

GO:0016428

sp|Q6PE18|P4K2A_DANRE
Phosphatidylinositol 4-kinase type 2-alpha
Search

PI4K2A

0.89	LOW QUALITY PROTEIN: phosphatidylinositol 4-kinase type 2-alpha

0.56	GO:0016310	phosphorylation
0.45	GO:0007032	endosome organization
0.44	GO:0007030	Golgi organization
0.43	GO:0046488	phosphatidylinositol metabolic process
0.43	GO:0030258	lipid modification
0.37	GO:0046474	glycerophospholipid biosynthetic process

0.58	GO:0016301	kinase activity
0.40	GO:0035651	AP-3 adaptor complex binding
0.39	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0044221	host cell synapse
0.47	GO:0072556	other organism presynaptic membrane
0.46	GO:0042734	presynaptic membrane
0.45	GO:0043025	neuronal cell body
0.45	GO:0030425	dendrite
0.44	GO:0005765	lysosomal membrane
0.44	GO:0005802	trans-Golgi network
0.43	GO:0005768	endosome
0.41	GO:0033644	host cell membrane
0.39	GO:0005739	mitochondrion

0.39

EC:2.7.1

GO:0016773

tr|Q6PE21|Q6PE21_DANRE
A kinase (PRKA) anchor protein 17A
Search

AKAP17A

0.96	Splicing factor, arginine/serine-rich 17A

0.74	GO:0043484	regulation of RNA splicing
0.48	GO:0016310	phosphorylation
0.35	GO:0042113	B cell activation
0.35	GO:0008380	RNA splicing
0.34	GO:0006397	mRNA processing
0.34	GO:0032259	methylation
0.34	GO:0007165	signal transduction
0.34	GO:0006606	protein import into nucleus
0.34	GO:0030041	actin filament polymerization
0.33	GO:0034314	Arp2/3 complex-mediated actin nucleation

0.76	GO:0051018	protein kinase A binding
0.49	GO:0016301	kinase activity
0.48	GO:0003723	RNA binding
0.36	GO:0008171	O-methyltransferase activity
0.34	GO:0061608	nuclear import signal receptor activity
0.34	GO:0004930	G-protein coupled receptor activity

0.49	GO:0016607	nuclear speck
0.44	GO:0005829	cytosol
0.35	GO:0005681	spliceosomal complex
0.33	GO:0005885	Arp2/3 protein complex
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0008171

sp|Q6PE25|EF1G_DANRE
Elongation factor 1-gamma
Search

EEF1G

0.71	Eukaryotic translation elongation factor 1 gamma

0.68	GO:0006414	translational elongation
0.48	GO:0009615	response to virus
0.43	GO:0006749	glutathione metabolic process
0.35	GO:0006378	mRNA polyadenylation
0.33	GO:0006351	transcription, DNA-templated
0.32	GO:0032259	methylation

0.69	GO:0003746	translation elongation factor activity
0.50	GO:0045296	cadherin binding
0.44	GO:0004364	glutathione transferase activity
0.35	GO:0050265	RNA uridylyltransferase activity
0.35	GO:0003730	mRNA 3'-UTR binding
0.34	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0008168	methyltransferase activity

0.45	GO:0005783	endoplasmic reticulum
0.40	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.44

EC:2.5.1.18

GO:0004364

tr|Q6PE27|Q6PE27_DANRE
Solute carrier family 13 (Sodium/sulphate symporters), member 1
Search

SLC13A1

0.94	Solute carrier family 13 (sodium-dependent citrate transporter), member 5b

0.72	GO:0006814	sodium ion transport
0.58	GO:0008272	sulfate transport
0.54	GO:0055085	transmembrane transport
0.37	GO:0015746	citrate transport
0.34	GO:0015744	succinate transport

0.59	GO:0015382	sodium:sulfate symporter activity
0.34	GO:0017153	sodium:dicarboxylate symporter activity
0.34	GO:0015141	succinate transmembrane transporter activity
0.34	GO:0015137	citrate transmembrane transporter activity

0.46

GO:0005887

integral component of plasma membrane

tr|Q6PE28|Q6PE28_DANRE
Ras homolog gene family, member Ga
Search

0.89	Rho-related GTP-binding protein RhoG

0.77	GO:0007264	small GTPase mediated signal transduction
0.44	GO:1903078	positive regulation of protein localization to plasma membrane
0.44	GO:0090630	activation of GTPase activity
0.43	GO:1900027	regulation of ruffle assembly
0.43	GO:0060326	cell chemotaxis
0.40	GO:0030036	actin cytoskeleton organization
0.40	GO:0045893	positive regulation of transcription, DNA-templated
0.37	GO:0043312	neutrophil degranulation
0.37	GO:0030168	platelet activation
0.36	GO:0008284	positive regulation of cell proliferation

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.36	GO:0012506	vesicle membrane
0.35	GO:0005886	plasma membrane
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.30	GO:0044425	membrane part

tr|Q6PE30|Q6PE30_DANRE
CCR4-NOT transcription complex, subunit 6
Search

CNOT6

0.90	CCR4-NOT transcription complex subunit 6

0.74	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.61	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly
0.60	GO:2000327	positive regulation of ligand-dependent nuclear receptor transcription coactivator activity
0.58	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.56	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic
0.56	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay
0.56	GO:0008284	positive regulation of cell proliferation
0.46	GO:0061157	mRNA destabilization
0.40	GO:0031047	gene silencing by RNA
0.38	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

0.83	GO:0004535	poly(A)-specific ribonuclease activity
0.35	GO:0003723	RNA binding
0.35	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.58	GO:0030014	CCR4-NOT complex
0.42	GO:0005829	cytosol
0.40	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.83

EC:3.1.13.4

GO:0004535

tr|Q6PE32|Q6PE32_DANRE
GRB2-related adaptor protein 2b
Search

GRAP2

0.81	Sex muscle abnormal protein 5 (inferred by orthology to a C. elegans protein)

0.61	GO:0038083	peptidyl-tyrosine autophosphorylation
0.57	GO:0016477	cell migration
0.57	GO:0045087	innate immune response
0.57	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.56	GO:0042127	regulation of cell proliferation
0.54	GO:0007265	Ras protein signal transduction
0.53	GO:0030154	cell differentiation
0.42	GO:0006886	intracellular protein transport
0.41	GO:1904669	ATP export
0.41	GO:1903319	positive regulation of protein maturation

0.58	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.54	GO:0005102	receptor binding
0.40	GO:0043130	ubiquitin binding
0.39	GO:0019904	protein domain specific binding
0.38	GO:0046982	protein heterodimerization activity
0.38	GO:0005070	SH3/SH2 adaptor activity
0.37	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.36	GO:0016746	transferase activity, transferring acyl groups

0.65	GO:0005768	endosome
0.57	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.54	GO:0005634	nucleus
0.39	GO:0044433	cytoplasmic vesicle part
0.36	GO:0043234	protein complex
0.35	GO:0005829	cytosol
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.30	GO:0031224	intrinsic component of membrane

0.58

EC:2.7.10.2

GO:0004715

tr|Q6PE34|Q6PE34_DANRE
Tubulin beta chain
Search

0.49	Tubulin beta chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.48	GO:0031115	negative regulation of microtubule polymerization
0.40	GO:1905792	positive regulation of mechanosensory behavior
0.40	GO:1905789	positive regulation of detection of mechanical stimulus involved in sensory perception of touch
0.39	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch
0.39	GO:0007638	mechanosensory behavior
0.37	GO:0097435	supramolecular fiber organization
0.36	GO:0070925	organelle assembly
0.35	GO:0022402	cell cycle process

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0005509	calcium ion binding
0.37	GO:0042288	MHC class I protein binding
0.35	GO:0031625	ubiquitin protein ligase binding
0.34	GO:0005164	tumor necrosis factor receptor binding

0.73	GO:0005874	microtubule
0.48	GO:0033269	internode region of axon
0.47	GO:0044297	cell body
0.47	GO:0005737	cytoplasm
0.46	GO:0036477	somatodendritic compartment
0.45	GO:0043209	myelin sheath
0.44	GO:0044441	ciliary part
0.36	GO:0005641	nuclear envelope lumen
0.36	GO:0070062	extracellular exosome
0.35	GO:0035770	ribonucleoprotein granule

tr|Q6PE45|Q6PE45_DANRE
RER1 homolog
Search

RER1

0.97	Retention in endoplasmic reticulum sorting receptor 1

0.56	GO:0071340	skeletal muscle acetylcholine-gated channel clustering
0.54	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.53	GO:1903078	positive regulation of protein localization to plasma membrane
0.40	GO:0060271	cilium assembly
0.34	GO:0016558	protein import into peroxisome matrix

0.55

GO:0033130

acetylcholine receptor binding

0.52	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.52	GO:0030173	integral component of Golgi membrane
0.49	GO:0009986	cell surface
0.41	GO:0005886	plasma membrane
0.34	GO:0005777	peroxisome

tr|Q6PEG4|Q6PEG4_DANRE
Elongation factor RNA polymerase II
Search

ELL

0.85	RNA polymerase II elongation factor ELL

0.84	GO:0042795	snRNA transcription by RNA polymerase II
0.80	GO:0006368	transcription elongation from RNA polymerase II promoter
0.62	GO:0006414	translational elongation
0.49	GO:0042796	snRNA transcription by RNA polymerase III
0.49	GO:0001570	vasculogenesis
0.49	GO:0045945	positive regulation of transcription by RNA polymerase III
0.46	GO:0010923	negative regulation of phosphatase activity
0.46	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.45	GO:0001701	in utero embryonic development

0.62	GO:0003746	translation elongation factor activity
0.47	GO:0019902	phosphatase binding

0.79	GO:0008023	transcription elongation factor complex
0.49	GO:0035363	histone locus body
0.48	GO:0015030	Cajal body
0.48	GO:0035327	transcriptionally active chromatin
0.46	GO:0016607	nuclear speck

sp|Q6PEH1|ERD22_DANRE
ER lumen protein-retaining receptor 2
Search

KDELR2

0.67	ER lumen protein-retaining receptor

0.84	GO:0006621	protein retention in ER lumen
0.65	GO:0015031	protein transport
0.38	GO:0016192	vesicle-mediated transport
0.33	GO:0046907	intracellular transport
0.33	GO:0006629	lipid metabolic process

0.84	GO:0046923	ER retention sequence binding
0.33	GO:0003676	nucleic acid binding
0.32	GO:0016787	hydrolase activity

0.71	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0005801	cis-Golgi network
0.36	GO:0070062	extracellular exosome
0.34	GO:0030133	transport vesicle
0.34	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

sp|Q6PEH4|DIEXF_DANRE
Digestive organ expansion factor
Search

DIEXF

0.91	Digestive organ expansion factor

0.48	GO:0090594	inflammatory response to wounding
0.47	GO:0031017	exocrine pancreas development
0.47	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.46	GO:0031648	protein destabilization
0.46	GO:0035265	organ growth
0.46	GO:0048546	digestive tract morphogenesis
0.42	GO:0030163	protein catabolic process

0.49	GO:0034511	U3 snoRNA binding
0.42	GO:0019843	rRNA binding
0.33	GO:0005515	protein binding

0.59	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.46	GO:0032040	small-subunit processome
0.46	GO:0043232	intracellular non-membrane-bounded organelle
0.45	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q6PEH5|UB2V2_DANRE
Ubiquitin-conjugating enzyme E2 variant 2
Search

UBE2V2

0.59	Ubiquitin-conjugating enzyme

0.75	GO:0070534	protein K63-linked ubiquitination
0.74	GO:0006301	postreplication repair
0.66	GO:0000729	DNA double-strand break processing
0.49	GO:0048584	positive regulation of response to stimulus
0.48	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.47	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling
0.46	GO:0048522	positive regulation of cellular process
0.45	GO:0023056	positive regulation of signaling
0.45	GO:0043524	negative regulation of neuron apoptotic process
0.45	GO:0051963	regulation of synapse assembly

0.67	GO:0061631	ubiquitin conjugating enzyme activity
0.61	GO:0031625	ubiquitin protein ligase binding
0.60	GO:0061630	ubiquitin protein ligase activity
0.36	GO:0003678	DNA helicase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0003677	DNA binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0031371	ubiquitin conjugating enzyme complex
0.60	GO:0005654	nucleoplasm
0.47	GO:0000151	ubiquitin ligase complex
0.43	GO:0005737	cytoplasm
0.41	GO:0070062	extracellular exosome
0.38	GO:0042555	MCM complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q6PEH8|MED25_DANRE
Mediator of RNA polymerase II transcription subunit 25
Search

MED25

0.94	Mediator of RNA polymerase II transcription subunit 25

0.84	GO:2001178	positive regulation of mediator complex assembly
0.81	GO:0035563	positive regulation of chromatin binding
0.79	GO:0048147	negative regulation of fibroblast proliferation
0.78	GO:0071158	positive regulation of cell cycle arrest
0.70	GO:0000122	negative regulation of transcription by RNA polymerase II
0.68	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0060021	palate development
0.45	GO:0006351	transcription, DNA-templated

0.81

GO:0046965

retinoid X receptor binding

0.67	GO:0044798	nuclear transcription factor complex
0.63	GO:0005654	nucleoplasm
0.41	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005886	plasma membrane

sp|Q6PEH9|S39AA_DANRE
Zinc transporter ZIP10
Search

SLC39A10

0.72	Zinc transporter ZIP10

0.66	GO:0030001	metal ion transport
0.55	GO:0055085	transmembrane transport
0.47	GO:0006882	cellular zinc ion homeostasis
0.45	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.44	GO:0010043	response to zinc ion
0.43	GO:0072511	divalent inorganic cation transport
0.42	GO:1903615	positive regulation of protein tyrosine phosphatase activity
0.41	GO:0002903	negative regulation of B cell apoptotic process
0.41	GO:0050861	positive regulation of B cell receptor signaling pathway
0.40	GO:0030890	positive regulation of B cell proliferation

0.69	GO:0046873	metal ion transmembrane transporter activity
0.44	GO:0072509	divalent inorganic cation transmembrane transporter activity

0.40

GO:0005887

integral component of plasma membrane

sp|Q6PEI3|PHR4B_DANRE
Phosphatase and actin regulator 4B
Search

0.62	Phosphatase and actin regulator

0.81	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.50	GO:2001045	negative regulation of integrin-mediated signaling pathway
0.50	GO:0061386	closure of optic fissure
0.48	GO:0048484	enteric nervous system development
0.48	GO:0001755	neural crest cell migration
0.47	GO:0001843	neural tube closure
0.47	GO:0007266	Rho protein signal transduction
0.44	GO:0030036	actin cytoskeleton organization
0.43	GO:0051726	regulation of cell cycle
0.43	GO:0043085	positive regulation of catalytic activity

0.82	GO:0004864	protein phosphatase inhibitor activity
0.74	GO:0003779	actin binding
0.61	GO:0008157	protein phosphatase 1 binding
0.49	GO:0072542	protein phosphatase activator activity
0.35	GO:0005199	structural constituent of cell wall

0.46	GO:0030027	lamellipodium
0.35	GO:0005622	intracellular

sp|Q6PEI7|PYRG1_DANRE
CTP synthase 1
Search

CTPS1

0.48	CTP synthase

0.76	GO:0044210	'de novo' CTP biosynthetic process
0.70	GO:0006541	glutamine metabolic process
0.55	GO:0042100	B cell proliferation
0.55	GO:0042098	T cell proliferation
0.35	GO:0015949	nucleobase-containing small molecule interconversion
0.33	GO:0042493	response to drug
0.33	GO:0035556	intracellular signal transduction

0.78	GO:0003883	CTP synthase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0042802	identical protein binding
0.33	GO:0016829	lyase activity

0.35	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.78

EC:6.3.4.2

GO:0003883

tr|Q6PEJ2|Q6PEJ2_DANRE
Adaptor-related protein complex 2, sigma 1 subunit
Search

AP2S1

0.56	AP complex subunit sigma

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.39	GO:0098657	import into cell
0.35	GO:0032802	low-density lipoprotein particle receptor catabolic process
0.35	GO:0034383	low-density lipoprotein particle clearance
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.34	GO:0060071	Wnt signaling pathway, planar cell polarity pathway
0.34	GO:0048013	ephrin receptor signaling pathway
0.34	GO:0048268	clathrin coat assembly
0.34	GO:0030100	regulation of endocytosis

0.71	GO:0008565	protein transporter activity
0.34	GO:0035615	clathrin adaptor activity
0.30	GO:0003824	catalytic activity

0.85	GO:0030122	AP-2 adaptor complex
0.35	GO:0036020	endolysosome membrane
0.34	GO:0008023	transcription elongation factor complex
0.33	GO:0005829	cytosol

tr|Q6PFI8|Q6PFI8_DANRE
Testis-specific protein, Y-linked
Search

0.94	Testis-specific protein, Y-linked

0.79	GO:0006334	nucleosome assembly
0.34	GO:0016573	histone acetylation
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.34	GO:0004402	histone acetyltransferase activity
0.34	GO:0019899	enzyme binding

0.61	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0031248	protein acetyltransferase complex
0.32	GO:0043234	protein complex

0.34

GO:0004402

tr|Q6PFI9|Q6PFI9_DANRE
Zgc:66427
Search

ZNRF1

0.81	Zinc and ring finger 1, E3 ubiquitin protein ligase

0.49	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.47	GO:0016567	protein ubiquitination
0.36	GO:0043043	peptide biosynthetic process
0.35	GO:0010467	gene expression
0.34	GO:0009059	macromolecule biosynthetic process

0.57	GO:0016874	ligase activity
0.48	GO:0061630	ubiquitin protein ligase activity
0.36	GO:0003735	structural constituent of ribosome
0.34	GO:0035091	phosphatidylinositol binding
0.33	GO:0046872	metal ion binding

0.37	GO:0005768	endosome
0.36	GO:0005829	cytosol
0.36	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.57

GO:0016874

tr|Q6PFJ0|Q6PFJ0_DANRE
Ribosomal protein L7-like 1
Search

RPL7L1

0.67	Ribosomal protein L7 like 1

0.51	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.50	GO:0001825	blastocyst formation
0.49	GO:0002181	cytoplasmic translation
0.40	GO:0051726	regulation of cell cycle

0.43	GO:0003735	structural constituent of ribosome
0.42	GO:0003723	RNA binding

0.58	GO:0005840	ribosome
0.47	GO:0044445	cytosolic part
0.45	GO:0005730	nucleolus

sp|Q6PFJ1|NGDN_DANRE
Neuroguidin
Search

NGDN

0.96	Neuroguidin-A

0.63	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.48	GO:0006417	regulation of translation
0.39	GO:0006888	ER to Golgi vesicle-mediated transport
0.37	GO:0006413	translational initiation
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:1903506	regulation of nucleic acid-templated transcription

0.38	GO:0003723	RNA binding
0.36	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.36	GO:0008146	sulfotransferase activity
0.35	GO:0005515	protein binding
0.35	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003677	DNA binding
0.34	GO:0016787	hydrolase activity

0.69	GO:0005730	nucleolus
0.62	GO:0032040	small-subunit processome
0.54	GO:0005739	mitochondrion
0.44	GO:0030175	filopodium
0.43	GO:0030425	dendrite
0.43	GO:0030424	axon
0.42	GO:0000775	chromosome, centromeric region
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:2.7.7.6

GO:0003899

sp|Q6PFJ7|NSMA3_DANRE
Sphingomyelin phosphodiesterase 4
Search

SMPD4

0.93	Sphingomyelin phosphodiesterase 4

0.36	GO:0046513	ceramide biosynthetic process
0.36	GO:0006685	sphingomyelin catabolic process
0.35	GO:0046475	glycerophospholipid catabolic process
0.35	GO:0071356	cellular response to tumor necrosis factor

0.86	GO:0050290	sphingomyelin phosphodiesterase D activity
0.43	GO:0004767	sphingomyelin phosphodiesterase activity
0.34	GO:0046872	metal ion binding

0.38	GO:0098791	Golgi subcompartment
0.37	GO:0005783	endoplasmic reticulum
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0098588	bounding membrane of organelle
0.30	GO:0031224	intrinsic component of membrane

0.86	EC:3.1.4.41	GO:0050290
0.86	KEGG:R02542	GO:0050290

sp|Q6PFJ9|ARI1_DANRE
E3 ubiquitin-protein ligase arih1
Search

ARIH1

0.58	RING-type E3 ubiquitin transferase

0.73	GO:0016567	protein ubiquitination
0.51	GO:0006511	ubiquitin-dependent protein catabolic process
0.48	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.32	GO:0006355	regulation of transcription, DNA-templated

0.73	GO:0004842	ubiquitin-protein transferase activity
0.58	GO:0031624	ubiquitin conjugating enzyme binding
0.53	GO:0046872	metal ion binding
0.51	GO:0016874	ligase activity
0.51	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0061659	ubiquitin-like protein ligase activity
0.33	GO:0008233	peptidase activity
0.33	GO:0017171	serine hydrolase activity
0.33	GO:0044212	transcription regulatory region DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.57	GO:0097413	Lewy body
0.56	GO:0031462	Cul2-RING ubiquitin ligase complex
0.55	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex
0.54	GO:0019005	SCF ubiquitin ligase complex
0.54	GO:0031463	Cul3-RING ubiquitin ligase complex
0.51	GO:0016604	nuclear body
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.51	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

sp|Q6PFK1|ZN598_DANRE
E3 ubiquitin-protein ligase ZNF598
Search

ZNF598

0.93	LOW QUALITY PROTEIN: zinc finger protein 598

0.41	GO:0072344	rescue of stalled ribosome
0.41	GO:0006513	protein monoubiquitination

0.51	GO:0003676	nucleic acid binding
0.40	GO:0061630	ubiquitin protein ligase activity
0.39	GO:0043022	ribosome binding
0.35	GO:0046872	metal ion binding
0.33	GO:0016874	ligase activity
0.33	GO:0005515	protein binding

0.33

GO:0016874

sp|Q6PFL0|MED27_DANRE
Mediator of RNA polymerase II transcription subunit 27
Search

MED27

0.93	Mediator of RNA polymerase II transcription subunit 27-A

0.71	GO:0019827	stem cell population maintenance
0.63	GO:0006357	regulation of transcription by RNA polymerase II
0.59	GO:0046549	retinal cone cell development
0.43	GO:0006351	transcription, DNA-templated
0.41	GO:0016567	protein ubiquitination

0.69	GO:0003713	transcription coactivator activity
0.42	GO:0061630	ubiquitin protein ligase activity
0.37	GO:0005515	protein binding

0.66	GO:0005667	transcription factor complex
0.66	GO:0016592	mediator complex
0.65	GO:0005730	nucleolus
0.61	GO:0005829	cytosol
0.42	GO:0000151	ubiquitin ligase complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q6PFL6|CCD43_DANRE
Coiled-coil domain-containing protein 43
Search

CCDC43

0.96	LOW QUALITY PROTEIN: coiled-coil domain-containing protein 43

0.37

GO:0005515

protein binding

0.67

GO:0005829

cytosol

sp|Q6PFL8|THYN1_DANRE
Thymocyte nuclear protein 1
Search

THYN1

0.94	Thymocyte nuclear protein 1

0.39	GO:0042147	retrograde transport, endosome to Golgi
0.37	GO:0006886	intracellular protein transport

0.37

GO:0008565

protein transporter activity

0.61	GO:0005634	nucleus
0.39	GO:0030904	retromer complex
0.38	GO:0005768	endosome
0.37	GO:0005829	cytosol

sp|Q6PFM0|JMJD6_DANRE
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6
Search

JMJD6

0.92	Arginine demethylase and lysine hydroxylase

0.61	GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine
0.61	GO:0070077	histone arginine demethylation
0.57	GO:0006909	phagocytosis
0.56	GO:0002040	sprouting angiogenesis
0.56	GO:0048024	regulation of mRNA splicing, via spliceosome
0.54	GO:0048821	erythrocyte development
0.54	GO:0033077	T cell differentiation in thymus
0.53	GO:0042116	macrophage activation
0.53	GO:0032259	methylation
0.52	GO:0030324	lung development

0.61	GO:0033749	histone demethylase activity (H4-R3 specific)
0.61	GO:0033746	histone demethylase activity (H3-R2 specific)
0.58	GO:0070815	peptidyl-lysine 5-dioxygenase activity
0.54	GO:0003727	single-stranded RNA binding
0.53	GO:0008168	methyltransferase activity
0.49	GO:0042802	identical protein binding
0.46	GO:0046983	protein dimerization activity
0.45	GO:0004872	receptor activity
0.44	GO:0005506	iron ion binding

0.51	GO:0005730	nucleolus
0.50	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol
0.43	GO:0030529	intracellular ribonucleoprotein complex
0.41	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.53

GO:0008168

sp|Q6PFM1|S20AB_DANRE
Sodium-dependent phosphate transporter 1-B
Search

SLC20A1

0.50	Sodium-dependent phosphate transporter 1-B

0.73	GO:0006817	phosphate ion transport
0.55	GO:0055085	transmembrane transport
0.45	GO:0006814	sodium ion transport
0.36	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.35	GO:0016032	viral process
0.34	GO:0007165	signal transduction
0.33	GO:0051828	entry into other organism involved in symbiotic interaction
0.32	GO:0006796	phosphate-containing compound metabolic process

0.75	GO:0005315	inorganic phosphate transmembrane transporter activity
0.51	GO:0005436	sodium:phosphate symporter activity
0.37	GO:0015370	solute:sodium symporter activity
0.36	GO:0015321	sodium-dependent phosphate transmembrane transporter activity
0.35	GO:0104005	hijacked molecular function
0.34	GO:0004871	signal transducer activity
0.34	GO:0004872	receptor activity
0.34	GO:0008146	sulfotransferase activity

0.43	GO:0005887	integral component of plasma membrane
0.34	GO:0070062	extracellular exosome

0.34

EC:2.8.2

GO:0008146

sp|Q6PFM4|LNPB_DANRE
Protein lunapark-B
Search

0.96	Endoplasmic reticulum junction formation protein lunapark-B

0.57	GO:0071788	endoplasmic reticulum tubular network maintenance
0.56	GO:1903373	positive regulation of endoplasmic reticulum tubular network organization
0.51	GO:0035115	embryonic forelimb morphogenesis
0.51	GO:0032330	regulation of chondrocyte differentiation
0.51	GO:0042733	embryonic digit morphogenesis
0.49	GO:0007596	blood coagulation

0.48	GO:0042802	identical protein binding
0.36	GO:0046872	metal ion binding

0.56	GO:0098826	endoplasmic reticulum tubular network membrane
0.50	GO:0030176	integral component of endoplasmic reticulum membrane
0.45	GO:0005654	nucleoplasm

sp|Q6PFM9|WDR48_DANRE
WD repeat-containing protein 48
Search

WDR48

0.93	WD repeat-containing protein 48

0.85	GO:1902525	regulation of protein monoubiquitination
0.84	GO:0072520	seminiferous tubule development
0.79	GO:0035264	multicellular organism growth
0.78	GO:0050679	positive regulation of epithelial cell proliferation
0.78	GO:0043588	skin development
0.78	GO:0007338	single fertilization
0.77	GO:0048705	skeletal system morphogenesis
0.75	GO:0007283	spermatogenesis
0.75	GO:0048568	embryonic organ development
0.74	GO:0016579	protein deubiquitination

0.39	GO:0016905	myosin heavy chain kinase activity
0.38	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.36	GO:0005515	protein binding

0.59	GO:0005634	nucleus
0.52	GO:0005770	late endosome
0.51	GO:0005764	lysosome
0.36	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part

0.39

EC:2.7.11.7

GO:0016905

sp|Q6PFP3|PDPFA_DANRE
Pancreatic progenitor cell differentiation and proliferation factor A
Search

0.97	Pancreatic progenitor cell differentiation and proliferation factor A

0.70	GO:0030154	cell differentiation
0.68	GO:0007275	multicellular organism development
0.44	GO:0008283	cell proliferation

sp|Q6PFP6|NDOR1_DANRE
NADPH-dependent diflavin oxidoreductase 1
Search

NDOR1

0.76	NADPH-dependent diflavin oxidoreductase 1

0.67	GO:0016226	iron-sulfur cluster assembly
0.56	GO:0036245	cellular response to menadione
0.52	GO:0055114	oxidation-reduction process
0.50	GO:0008219	cell death
0.38	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death
0.38	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.37	GO:0006809	nitric oxide biosynthetic process

0.78	GO:0003958	NADPH-hemoprotein reductase activity
0.69	GO:0010181	FMN binding
0.65	GO:0050661	NADP binding
0.61	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0005515	protein binding

0.68	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0045111	intermediate filament cytoskeleton
0.47	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.35	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.78

EC:1.6.2.4

GO:0003958

sp|Q6PFQ0|KS6A6_DANRE
Ribosomal protein S6 kinase alpha-6
Search

RPS6KA6

0.75	Ribosomal protein S6 kinase alpha-6

0.62	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.43	GO:0006974	cellular response to DNA damage stimulus
0.39	GO:0032269	negative regulation of cellular protein metabolic process
0.39	GO:2000381	negative regulation of mesoderm development
0.39	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.39	GO:0002224	toll-like receptor signaling pathway
0.39	GO:0032496	response to lipopolysaccharide
0.39	GO:0045992	negative regulation of embryonic development
0.38	GO:0043066	negative regulation of apoptotic process

0.69	GO:0004674	protein serine/threonine kinase activity
0.63	GO:0000287	magnesium ion binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.38	GO:0019901	protein kinase binding
0.34	GO:0003743	translation initiation factor activity

0.50	GO:0001650	fibrillar center
0.42	GO:0005739	mitochondrion
0.34	GO:0005829	cytosol
0.34	GO:0005840	ribosome
0.33	GO:0005654	nucleoplasm

0.69

GO:0004674

sp|Q6PFQ2|EIF3C_DANRE
Eukaryotic translation initiation factor 3 subunit C
Search

EIF3C

0.70	Eukaryotic translation initiation factor 3 subunit C

0.76	GO:0001731	formation of translation preinitiation complex
0.74	GO:0006446	regulation of translational initiation
0.39	GO:1902416	positive regulation of mRNA binding
0.37	GO:0045727	positive regulation of translation

0.81	GO:0031369	translation initiation factor binding
0.71	GO:0003743	translation initiation factor activity
0.34	GO:0043022	ribosome binding

0.76	GO:0005852	eukaryotic translation initiation factor 3 complex
0.75	GO:0016282	eukaryotic 43S preinitiation complex
0.75	GO:0033290	eukaryotic 48S preinitiation complex
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|Q6PFQ3|Q6PFQ3_DANRE
Peroxisomal biogenesis factor 13
Search

PEX13

0.95	Peroxisomal biogenesis factor 13

0.84	GO:0016560	protein import into peroxisome matrix, docking
0.59	GO:0060152	microtubule-based peroxisome localization
0.58	GO:0001561	fatty acid alpha-oxidation
0.56	GO:0021795	cerebral cortex cell migration
0.55	GO:0001967	suckling behavior
0.55	GO:0001764	neuron migration
0.54	GO:0007626	locomotory behavior
0.35	GO:0002119	nematode larval development
0.33	GO:0000956	nuclear-transcribed mRNA catabolic process
0.33	GO:0000398	mRNA splicing, via spliceosome

0.35	GO:0000268	peroxisome targeting sequence binding
0.33	GO:0005515	protein binding

0.76	GO:0005777	peroxisome
0.53	GO:0031903	microbody membrane
0.51	GO:0031301	integral component of organelle membrane

tr|Q6PFR9|Q6PFR9_DANRE
Even-skipped homeobox 2
Search

EVX2

0.96	Homeobox even-skipped like protein 1

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0035107	appendage morphogenesis
0.51	GO:0060173	limb development
0.48	GO:0021521	ventral spinal cord interneuron specification
0.45	GO:0009792	embryo development ending in birth or egg hatching
0.43	GO:1902680	positive regulation of RNA biosynthetic process
0.38	GO:0033333	fin development
0.31	GO:0006351	transcription, DNA-templated

0.64	GO:0043565	sequence-specific DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.41	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q6PFS2|PRXD1_DANRE
Prolyl-tRNA synthetase associated domain-containing protein 1
Search

0.95	Prolyl-tRNA synthetase associated domain-containing protein 1

0.73	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.36	GO:0006433	prolyl-tRNA aminoacylation
0.34	GO:0016579	protein deubiquitination

0.73	GO:0002161	aminoacyl-tRNA editing activity
0.53	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.35	GO:0003677	DNA binding
0.34	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.53

EC:6.1

GO:0016875

tr|Q6PFS3|Q6PFS3_DANRE
Voltage-dependent calcium channel gamma subunit
Search

CACNG2

0.47	Multifunctional fusion protein (Fragment)

0.74	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0070588	calcium ion transmembrane transport
0.58	GO:0098953	receptor diffusion trapping
0.58	GO:0098943	neurotransmitter receptor transport, postsynaptic endosome to lysosome
0.57	GO:0099590	neurotransmitter receptor internalization
0.56	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels
0.56	GO:1900449	regulation of glutamate receptor signaling pathway
0.56	GO:0060081	membrane hyperpolarization
0.56	GO:0099601	regulation of neurotransmitter receptor activity
0.56	GO:0019226	transmission of nerve impulse

0.78	GO:0005245	voltage-gated calcium channel activity
0.44	GO:0016247	channel regulator activity
0.37	GO:0003700	DNA binding transcription factor activity
0.36	GO:0003677	DNA binding
0.36	GO:0035255	ionotropic glutamate receptor binding

0.77	GO:0005891	voltage-gated calcium channel complex
0.56	GO:0032281	AMPA glutamate receptor complex
0.56	GO:0099634	postsynaptic specialization membrane
0.51	GO:0036477	somatodendritic compartment
0.37	GO:0005622	intracellular
0.35	GO:0014069	postsynaptic density

tr|Q6PFS4|Q6PFS4_DANRE
MICOS complex subunit MIC60
Search

IMMT

0.71	MICOS complex subunit MIC60

0.53	GO:0051560	mitochondrial calcium ion homeostasis
0.52	GO:0042407	cristae formation

0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.51	GO:0043209	myelin sheath
0.48	GO:0031301	integral component of organelle membrane
0.48	GO:0098798	mitochondrial protein complex
0.43	GO:0098796	membrane protein complex

sp|Q6PFS5|ERD23_DANRE
ER lumen protein-retaining receptor 3
Search

KDELR3

0.66	ER lumen protein-retaining receptor

0.84	GO:0006621	protein retention in ER lumen
0.64	GO:0015031	protein transport
0.39	GO:0016192	vesicle-mediated transport
0.35	GO:0036498	IRE1-mediated unfolded protein response
0.33	GO:0046907	intracellular transport
0.33	GO:0006629	lipid metabolic process

0.84	GO:0046923	ER retention sequence binding
0.32	GO:0003676	nucleic acid binding
0.32	GO:0016787	hydrolase activity

0.71	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0005801	cis-Golgi network
0.35	GO:0031982	vesicle
0.35	GO:0043230	extracellular organelle
0.35	GO:0000139	Golgi membrane
0.35	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

sp|Q6PFS7|ATG3_DANRE
Ubiquitin-like-conjugating enzyme ATG3
Search

ATG3

0.74	Autophagy-related protein 3

0.76	GO:0006914	autophagy
0.65	GO:0015031	protein transport
0.55	GO:0043653	mitochondrial fragmentation involved in apoptotic process
0.55	GO:0050765	negative regulation of phagocytosis
0.53	GO:1902017	regulation of cilium assembly
0.52	GO:0007033	vacuole organization
0.48	GO:0070925	organelle assembly
0.48	GO:0016567	protein ubiquitination
0.45	GO:0061726	mitochondrion disassembly
0.32	GO:0055114	oxidation-reduction process

0.57	GO:0019776	Atg8 ligase activity
0.56	GO:0019777	Atg12 transferase activity
0.47	GO:0019899	enzyme binding
0.32	GO:0005507	copper ion binding
0.32	GO:0016491	oxidoreductase activity

0.55	GO:0000153	cytoplasmic ubiquitin ligase complex
0.47	GO:0005829	cytosol

0.32

GO:0016491

tr|Q6PFS8|Q6PFS8_DANRE
Eukaryotic translation initiation factor 4E-binding protein 1
Search

EIF4EBP2

0.92	Eukaryotic translation initiation factor 4E-binding protein 1

0.82	GO:0045947	negative regulation of translational initiation
0.60	GO:0006413	translational initiation
0.49	GO:0031929	TOR signaling
0.48	GO:0008286	insulin receptor signaling pathway
0.47	GO:0035176	social behavior
0.46	GO:0007613	memory
0.46	GO:0019933	cAMP-mediated signaling
0.46	GO:0048167	regulation of synaptic plasticity
0.41	GO:0000082	G1/S transition of mitotic cell cycle
0.41	GO:0045931	positive regulation of mitotic cell cycle

0.86	GO:0008190	eukaryotic initiation factor 4E binding
0.61	GO:0003743	translation initiation factor activity
0.51	GO:0030371	translation repressor activity
0.36	GO:0051721	protein phosphatase 2A binding

0.39	GO:0005829	cytosol
0.34	GO:0016281	eukaryotic translation initiation factor 4F complex
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|Q6PFT0|Q6PFT0_DANRE
Flotillin 2b
Search

FLOT2

0.89	Dehydrogenase/reductase 13

0.83	GO:0044860	protein localization to plasma membrane raft
0.80	GO:1902992	negative regulation of amyloid precursor protein catabolic process
0.79	GO:0045661	regulation of myoblast differentiation
0.76	GO:0001765	membrane raft assembly
0.73	GO:0072659	protein localization to plasma membrane
0.70	GO:0050821	protein stabilization
0.68	GO:1903905	positive regulation of establishment of T cell polarity
0.61	GO:0010629	negative regulation of gene expression
0.52	GO:0007155	cell adhesion
0.48	GO:0034139	regulation of toll-like receptor 3 signaling pathway

0.66	GO:0046982	protein heterodimerization activity
0.55	GO:0035255	ionotropic glutamate receptor binding
0.53	GO:0002020	protease binding

0.82	GO:0016600	flotillin complex
0.80	GO:0002080	acrosomal membrane
0.79	GO:0001931	uropod
0.76	GO:0030139	endocytic vesicle
0.75	GO:0044291	cell-cell contact zone
0.74	GO:0005913	cell-cell adherens junction
0.73	GO:0030027	lamellipodium
0.73	GO:0016323	basolateral plasma membrane
0.71	GO:0030864	cortical actin cytoskeleton
0.71	GO:0005768	endosome

tr|Q6PFT1|Q6PFT1_DANRE
Fructose-1,6-bisphosphatase 1a
Search

0.49	Acipenser baerii fructose 1,6-bisphosphatase mRNA

0.68	GO:0016311	dephosphorylation
0.60	GO:0005975	carbohydrate metabolic process
0.51	GO:0071286	cellular response to magnesium ion
0.51	GO:0006002	fructose 6-phosphate metabolic process
0.50	GO:0045820	negative regulation of glycolytic process
0.49	GO:0030388	fructose 1,6-bisphosphate metabolic process
0.48	GO:0051289	protein homotetramerization
0.48	GO:0006111	regulation of gluconeogenesis
0.48	GO:0046580	negative regulation of Ras protein signal transduction
0.48	GO:0030308	negative regulation of cell growth

0.79	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity
0.50	GO:0042802	identical protein binding
0.48	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.47	GO:0016208	AMP binding
0.40	GO:0048029	monosaccharide binding
0.39	GO:0046872	metal ion binding
0.35	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity

0.45	GO:0005634	nucleus
0.44	GO:0005829	cytosol
0.43	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part
0.39	GO:0005886	plasma membrane
0.38	GO:0030018	Z disc
0.38	GO:0070062	extracellular exosome
0.37	GO:0030054	cell junction

0.79

EC:3.1.3.11

GO:0042132

sp|Q6PFT6|TMM47_DANRE
Transmembrane protein 47
Search

TMEM47

0.96	Transmembrane protein 47

0.33

GO:0005515

protein binding

0.49	GO:0030054	cell junction
0.41	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q6PFT7|Q6PFT7_DANRE
Coactosin-like 1
Search

COTL1

0.97	Coactosin like F-actin binding protein 1

0.53	GO:0050832	defense response to fungus
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0001755	neural crest cell migration
0.35	GO:0030041	actin filament polymerization

0.74	GO:0003779	actin binding
0.49	GO:0019899	enzyme binding

0.45	GO:0005622	intracellular
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.35	GO:0043228	non-membrane-bounded organelle
0.33	GO:0012505	endomembrane system

sp|Q6PFT9|AB1IP_DANRE
Amyloid beta A4 precursor protein-binding family B member 1-interacting protein
Search

APBB1IP

0.96	Amyloid beta A4 protein-binding family B member 1-interacting protein isoform A

0.61	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
0.60	GO:0007165	signal transduction
0.52	GO:0045785	positive regulation of cell adhesion
0.35	GO:0048675	axon extension

0.35

GO:0005515

protein binding

0.58	GO:0042101	T cell receptor complex
0.49	GO:0005829	cytosol
0.38	GO:0031252	cell leading edge
0.37	GO:0005856	cytoskeleton
0.37	GO:0005925	focal adhesion
0.36	GO:0120025	plasma membrane bounded cell projection
0.34	GO:0016604	nuclear body
0.30	GO:0016021	integral component of membrane

tr|Q6PFU1|Q6PFU1_DANRE
Tetraspanin
Search

CD81

0.59	Tetraspanin

0.55	GO:0043126	regulation of 1-phosphatidylinositol 4-kinase activity
0.53	GO:1904352	positive regulation of protein catabolic process in the vacuole
0.53	GO:0090218	positive regulation of lipid kinase activity
0.52	GO:0071404	cellular response to low-density lipoprotein particle stimulus
0.52	GO:1903727	positive regulation of phospholipid metabolic process
0.51	GO:0061462	protein localization to lysosome
0.51	GO:0000187	activation of MAPK activity
0.51	GO:0030890	positive regulation of B cell proliferation
0.51	GO:0031623	receptor internalization
0.51	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation

0.52	GO:1990459	transferrin receptor binding
0.52	GO:0001618	virus receptor activity

0.51	GO:0001772	immunological synapse
0.49	GO:0016323	basolateral plasma membrane
0.49	GO:0070062	extracellular exosome
0.46	GO:0005887	integral component of plasma membrane

tr|Q6PFV0|Q6PFV0_DANRE
F-box and WD repeat domain-containing 5
Search

FBXW5

0.96	F-box and WD repeat domain-containing 5

0.80	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.79	GO:0010824	regulation of centrosome duplication
0.72	GO:0007088	regulation of mitotic nuclear division
0.69	GO:0016567	protein ubiquitination
0.38	GO:0043687	post-translational protein modification

0.71	GO:0019901	protein kinase binding
0.43	GO:0004842	ubiquitin-protein transferase activity

0.79	GO:0080008	Cul4-RING E3 ubiquitin ligase complex
0.78	GO:0019005	SCF ubiquitin ligase complex
0.47	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.43

GO:0004842

tr|Q6PFV1|Q6PFV1_DANRE
CAMP-regulated phosphoprotein 19a
Search

ENSA

0.89	LOW QUALITY PROTEIN: cAMP-regulated phosphoprotein 19

0.81	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.66	GO:0051301	cell division
0.66	GO:0007049	cell cycle
0.50	GO:0050796	regulation of insulin secretion
0.37	GO:0009749	response to glucose
0.37	GO:0045722	positive regulation of gluconeogenesis
0.35	GO:0046579	positive regulation of Ras protein signal transduction
0.35	GO:0007212	dopamine receptor signaling pathway
0.34	GO:0007584	response to nutrient

0.82	GO:0004864	protein phosphatase inhibitor activity
0.53	GO:0019870	potassium channel inhibitor activity
0.47	GO:0005102	receptor binding
0.43	GO:0051721	protein phosphatase 2A binding
0.34	GO:0019901	protein kinase binding

0.48	GO:0005737	cytoplasm
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q6PG29|SKAP2_DANRE
Src kinase-associated phosphoprotein 2
Search

SKAP2

0.95	Src kinase-associated phosphoprotein 2-A

0.54	GO:0008285	negative regulation of cell proliferation
0.53	GO:0002757	immune response-activating signal transduction
0.51	GO:0016310	phosphorylation
0.49	GO:0009967	positive regulation of signal transduction
0.45	GO:0042113	B cell activation
0.44	GO:0002768	immune response-regulating cell surface receptor signaling pathway
0.43	GO:0072659	protein localization to plasma membrane
0.42	GO:0045785	positive regulation of cell adhesion
0.41	GO:0045944	positive regulation of transcription by RNA polymerase II
0.38	GO:0002250	adaptive immune response

0.53	GO:0005070	SH3/SH2 adaptor activity
0.53	GO:0016301	kinase activity
0.45	GO:0042169	SH2 domain binding
0.44	GO:0019903	protein phosphatase binding
0.42	GO:0019901	protein kinase binding
0.36	GO:0032403	protein complex binding
0.34	GO:0017124	SH3 domain binding

0.51	GO:0005829	cytosol
0.49	GO:0005654	nucleoplasm
0.45	GO:0005886	plasma membrane
0.42	GO:0043235	receptor complex
0.42	GO:0005911	cell-cell junction
0.30	GO:0016021	integral component of membrane

sp|Q6PG31|RNPS1_DANRE
RNA-binding protein with serine-rich domain 1
Search

RNPS1

0.69	RNA-binding protein with serine-rich domain 1-A

0.55	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.53	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.52	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.51	GO:0043065	positive regulation of apoptotic process
0.42	GO:0008380	RNA splicing
0.41	GO:0006397	mRNA processing
0.35	GO:0006369	termination of RNA polymerase II transcription
0.35	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0031123	RNA 3'-end processing
0.34	GO:0051028	mRNA transport

0.57	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.57	GO:0061574	ASAP complex
0.50	GO:0005654	nucleoplasm
0.39	GO:0005737	cytoplasm
0.35	GO:0035145	exon-exon junction complex

sp|Q6PG34|CDKAL_DANRE
Threonylcarbamoyladenosine tRNA methylthiotransferase
Search

CDKAL1

0.92	Threonylcarbamoyladenosine tRNA methylthiotransferase

0.67	GO:0006400	tRNA modification
0.55	GO:1990145	maintenance of translational fidelity
0.36	GO:1990798	pancreas regeneration
0.36	GO:0003323	type B pancreatic cell development
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.32	GO:0055114	oxidation-reduction process

0.67	GO:0051539	4 iron, 4 sulfur cluster binding
0.57	GO:0035598	N6-threonylcarbomyladenosine methylthiotransferase activity
0.44	GO:0061712	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
0.38	GO:0046983	protein dimerization activity
0.36	GO:0003700	DNA binding transcription factor activity
0.35	GO:0046872	metal ion binding
0.35	GO:0003677	DNA binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity

0.51	GO:0005791	rough endoplasmic reticulum
0.39	GO:0005667	transcription factor complex
0.38	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.44

EC:2.8.4.5

GO:0061712

sp|Q6PGU2|MAF1_DANRE
Repressor of RNA polymerase III transcription MAF1 homolog
Search

MAF1

0.80	Repressor of RNA polymerase III transcription MAF1

0.85	GO:0016480	negative regulation of transcription by RNA polymerase III
0.55	GO:0006351	transcription, DNA-templated

0.52	GO:0001031	RNA polymerase III type 2 promoter DNA binding
0.52	GO:0001030	RNA polymerase III type 1 promoter DNA binding
0.52	GO:0001032	RNA polymerase III type 3 promoter DNA binding
0.48	GO:0000994	RNA polymerase III core binding
0.38	GO:0050811	GABA receptor binding

0.58	GO:0005634	nucleus
0.44	GO:0031974	membrane-enclosed lumen
0.41	GO:0043232	intracellular non-membrane-bounded organelle
0.40	GO:0044446	intracellular organelle part
0.38	GO:0060077	inhibitory synapse
0.38	GO:0005737	cytoplasm
0.37	GO:0030425	dendrite
0.37	GO:0030424	axon
0.34	GO:0005886	plasma membrane

sp|Q6PGV1|VA0D1_DANRE
V-type proton ATPase subunit d 1
Search

ATP6V0D1

0.68	V-type proton ATPase subunit

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.54	GO:0036295	cellular response to increased oxygen levels
0.49	GO:0030003	cellular cation homeostasis
0.48	GO:0055072	iron ion homeostasis
0.47	GO:0035675	neuromast hair cell development
0.47	GO:0008057	eye pigment granule organization
0.47	GO:0039022	pronephric duct development
0.47	GO:0003406	retinal pigment epithelium development
0.46	GO:0070986	left/right axis specification
0.46	GO:0045851	pH reduction

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.51	GO:0036442	proton-exporting ATPase activity
0.49	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.42	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.36	GO:0032403	protein complex binding

0.79	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.53	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.52	GO:0005769	early endosome
0.49	GO:0005813	centrosome
0.46	GO:0005765	lysosomal membrane
0.40	GO:0016324	apical plasma membrane
0.38	GO:0043679	axon terminus
0.37	GO:0008021	synaptic vesicle
0.36	GO:0070062	extracellular exosome
0.35	GO:0030670	phagocytic vesicle membrane

sp|Q6PGW3|CJ076_DANRE
UPF0668 protein C10orf76 homolog
Search

0.42

GO:0005515

protein binding

0.30

GO:0044425

membrane part

tr|Q6PGW5|Q6PGW5_DANRE
Family with sequence similarity 84, member A
Search

0.11	Phospholipid-metabolizing enzyme A-C1

0.36

GO:0005515

protein binding

0.53	GO:0005886	plasma membrane
0.47	GO:0005737	cytoplasm

sp|Q6PGX3|LRFN1_DANRE
Leucine-rich repeat and fibronectin type III domain-containing protein 1
Search

LRFN1

0.88	Leucine-rich repeat and fibronectin type III domain-containing protein 1

0.49	GO:0007409	axonogenesis
0.35	GO:0007259	JAK-STAT cascade
0.35	GO:0050778	positive regulation of immune response
0.34	GO:0051607	defense response to virus
0.34	GO:0010469	regulation of receptor activity

0.35	GO:0005125	cytokine activity
0.34	GO:0003779	actin binding

0.49	GO:0009986	cell surface
0.47	GO:0005578	proteinaceous extracellular matrix
0.47	GO:0005615	extracellular space
0.40	GO:0045202	synapse
0.40	GO:0030054	cell junction
0.37	GO:0098590	plasma membrane region
0.37	GO:0097458	neuron part
0.34	GO:0043226	organelle
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

tr|Q6PGX4|Q6PGX4_DANRE
Heat shock cognate 70
Search

0.61	Heat shock cognate protein isoform A

0.52	GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy
0.51	GO:0061738	late endosomal microautophagy
0.51	GO:0072318	clathrin coat disassembly
0.50	GO:0044829	positive regulation by host of viral genome replication
0.49	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.48	GO:0051085	chaperone cofactor-dependent protein refolding
0.47	GO:1902904	negative regulation of supramolecular fiber organization
0.47	GO:0031647	regulation of protein stability
0.46	GO:0042026	protein refolding
0.45	GO:0045892	negative regulation of transcription, DNA-templated

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0055131	C3HC4-type RING finger domain binding
0.49	GO:0001786	phosphatidylserine binding
0.48	GO:0045296	cadherin binding
0.47	GO:0001664	G-protein coupled receptor binding
0.47	GO:0031072	heat shock protein binding
0.47	GO:0031625	ubiquitin protein ligase binding

0.50	GO:0000974	Prp19 complex
0.48	GO:0070062	extracellular exosome
0.47	GO:0043209	myelin sheath
0.47	GO:0005770	late endosome
0.46	GO:0000151	ubiquitin ligase complex
0.44	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.42	GO:0030529	intracellular ribonucleoprotein complex
0.41	GO:0042470	melanosome
0.38	GO:0043202	lysosomal lumen

tr|Q6PGY3|Q6PGY3_DANRE
Solute carrier family 25 (Mitochondrial carrier citrate transporter), member 1
Search

0.48	Tricarboxylate transport protein, mitochondrial

0.52	GO:0006843	mitochondrial citrate transport
0.49	GO:0055085	transmembrane transport
0.42	GO:0010821	regulation of mitochondrion organization
0.38	GO:0048268	clathrin coat assembly
0.36	GO:0006886	intracellular protein transport
0.36	GO:0016192	vesicle-mediated transport
0.36	GO:0046326	positive regulation of glucose import
0.35	GO:0016482	cytosolic transport
0.35	GO:0016197	endosomal transport
0.35	GO:0000278	mitotic cell cycle

0.49	GO:0015137	citrate transmembrane transporter activity
0.39	GO:0032051	clathrin light chain binding
0.35	GO:0005198	structural molecule activity

0.44	GO:0031090	organelle membrane
0.43	GO:0005740	mitochondrial envelope
0.39	GO:0071439	clathrin complex
0.38	GO:0030140	trans-Golgi network transport vesicle
0.38	GO:0030132	clathrin coat of coated pit
0.37	GO:0044433	cytoplasmic vesicle part
0.37	GO:0044431	Golgi apparatus part
0.37	GO:0097443	sorting endosome
0.36	GO:0070062	extracellular exosome
0.35	GO:0005770	late endosome

sp|Q6PGY5|DJC21_DANRE
DnaJ homolog subfamily C member 21
Search

DNAJC21

0.87	DnaJ like protein subfamily C member 21

0.34

GO:0006457

protein folding

0.62	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.33	GO:0005515	protein binding

0.36	GO:0005730	nucleolus
0.33	GO:0005737	cytoplasm
0.33	GO:1990904	ribonucleoprotein complex

sp|Q6PGY6|UFL1_DANRE
E3 UFM1-protein ligase 1
Search

UFL1

0.95	UFM1-specific ligase 1

0.62	GO:0071569	protein ufmylation
0.60	GO:1902065	response to L-glutamate
0.60	GO:0033146	regulation of intracellular estrogen receptor signaling pathway
0.60	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.59	GO:0060252	positive regulation of glial cell proliferation
0.58	GO:0031397	negative regulation of protein ubiquitination
0.57	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
0.55	GO:0034976	response to endoplasmic reticulum stress
0.53	GO:0032880	regulation of protein localization
0.38	GO:0043066	negative regulation of apoptotic process

0.64	GO:0071568	UFM1 transferase activity
0.57	GO:0016874	ligase activity
0.35	GO:0005515	protein binding

0.53	GO:0043005	neuron projection
0.52	GO:0005783	endoplasmic reticulum
0.51	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.49	GO:0031984	organelle subcompartment
0.45	GO:0043234	protein complex
0.38	GO:0005829	cytosol
0.30	GO:0044425	membrane part

0.57

GO:0016874

tr|Q6PGY7|Q6PGY7_DANRE
CDGSH iron sulfur domain 1
Search

CISD1

0.66	CDGSH iron-sulfur domain-containing protein 1

0.47	GO:0043457	regulation of cellular respiration
0.37	GO:0000422	autophagy of mitochondrion
0.37	GO:0010259	multicellular organism aging
0.36	GO:0010506	regulation of autophagy
0.33	GO:0051186	cofactor metabolic process
0.32	GO:0006757	ATP generation from ADP
0.32	GO:0033014	tetrapyrrole biosynthetic process
0.32	GO:0006090	pyruvate metabolic process
0.32	GO:0016192	vesicle-mediated transport
0.32	GO:0016052	carbohydrate catabolic process

0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.47	GO:0042802	identical protein binding
0.35	GO:0046983	protein dimerization activity
0.34	GO:0046872	metal ion binding
0.33	GO:0004853	uroporphyrinogen decarboxylase activity
0.33	GO:0004619	phosphoglycerate mutase activity
0.32	GO:0022857	transmembrane transporter activity

0.56	GO:0043231	intracellular membrane-bounded organelle
0.45	GO:0031968	organelle outer membrane
0.40	GO:0044444	cytoplasmic part
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.35	GO:0070062	extracellular exosome
0.34	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:4.1.1.37

GO:0004853

tr|Q6PGY9|Q6PGY9_DANRE
Ectonucleotide pyrophosphatase/phosphodiesterase 2
Search

ENPP2

0.95	Ectonucleotide pyrophosphatase/phosphodiesterase 2

0.81	GO:0045765	regulation of angiogenesis
0.78	GO:0030334	regulation of cell migration
0.72	GO:0006955	immune response
0.71	GO:0006935	chemotaxis
0.70	GO:0006898	receptor-mediated endocytosis
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.51	GO:0034638	phosphatidylcholine catabolic process
0.51	GO:2000394	positive regulation of lamellipodium morphogenesis
0.48	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.47	GO:2000147	positive regulation of cell motility

0.86	GO:0004528	phosphodiesterase I activity
0.82	GO:0004622	lysophospholipase activity
0.80	GO:0004551	nucleotide diphosphatase activity
0.79	GO:0005044	scavenger receptor activity
0.77	GO:0001871	pattern binding
0.68	GO:0030246	carbohydrate binding
0.53	GO:0046872	metal ion binding
0.50	GO:0003676	nucleic acid binding
0.46	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity
0.34	GO:0008134	transcription factor binding

0.44	GO:0005615	extracellular space
0.35	GO:0005887	integral component of plasma membrane
0.33	GO:0005794	Golgi apparatus

0.86

EC:3.1.4.1

GO:0004528

sp|Q6PGZ0|CEP63_DANRE
Centrosomal protein of 63 kDa
Search

CEP63

0.78	Centrosomal protein of

0.85	GO:0098534	centriole assembly
0.84	GO:0051298	centrosome duplication
0.68	GO:1903251	multi-ciliated epithelial cell differentiation
0.58	GO:0042770	signal transduction in response to DNA damage
0.56	GO:0051225	spindle assembly
0.55	GO:0000077	DNA damage checkpoint
0.49	GO:0051301	cell division
0.42	GO:0051640	organelle localization
0.41	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
0.41	GO:0071539	protein localization to centrosome

0.38

GO:0005515

protein binding

0.76	GO:0005813	centrosome
0.65	GO:0005814	centriole
0.55	GO:0000922	spindle pole
0.38	GO:0098536	deuterosome
0.37	GO:0005829	cytosol

sp|Q6PGZ3|MIPT3_DANRE
TRAF3-interacting protein 1
Search

TRAF3IP1

0.86	TRAF3-interacting protein 1 isoform 2

0.74

GO:0008017

microtubule binding

tr|Q6PGZ7|Q6PGZ7_DANRE
Interferon regulatory factor 6
Search

0.90	Interferon regulatory factor 6

0.57	GO:0006351	transcription, DNA-templated
0.56	GO:0043616	keratinocyte proliferation
0.56	GO:0006357	regulation of transcription by RNA polymerase II
0.55	GO:0060429	epithelium development
0.54	GO:0019221	cytokine-mediated signaling pathway
0.53	GO:0007050	cell cycle arrest
0.53	GO:0043588	skin development
0.53	GO:0051607	defense response to virus
0.53	GO:0008544	epidermis development
0.52	GO:0008285	negative regulation of cell proliferation

0.75	GO:0044212	transcription regulatory region DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.47	GO:0043565	sequence-specific DNA binding
0.41	GO:0042802	identical protein binding

0.60	GO:0005634	nucleus
0.50	GO:0030054	cell junction
0.47	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

tr|Q6PGZ9|Q6PGZ9_DANRE
Ephrin A1a
Search

0.83	GO:0048013	ephrin receptor signaling pathway
0.53	GO:0010771	negative regulation of cell morphogenesis involved in differentiation
0.53	GO:0000904	cell morphogenesis involved in differentiation
0.52	GO:0050730	regulation of peptidyl-tyrosine phosphorylation
0.52	GO:0030182	neuron differentiation
0.52	GO:0050807	regulation of synapse organization
0.51	GO:0050770	regulation of axonogenesis
0.51	GO:1905247	positive regulation of aspartic-type peptidase activity
0.51	GO:0061000	negative regulation of dendritic spine development
0.51	GO:1902959	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

0.85	GO:0046875	ephrin receptor binding
0.46	GO:0005169	neurotrophin TRKB receptor binding
0.45	GO:0045499	chemorepellent activity
0.34	GO:0005170	neurotrophin TRKC receptor binding
0.34	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.34	GO:0005168	neurotrophin TRKA receptor binding
0.34	GO:0005005	transmembrane-ephrin receptor activity
0.33	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
0.32	GO:0008168	methyltransferase activity

0.54	GO:0046658	anchored component of plasma membrane
0.45	GO:0031233	intrinsic component of external side of plasma membrane
0.43	GO:0005604	basement membrane
0.42	GO:0005912	adherens junction
0.35	GO:0005901	caveola
0.35	GO:0070062	extracellular exosome
0.33	GO:0005887	integral component of plasma membrane

0.33

EC:1.14.11

GO:0016706

tr|Q6PH06|Q6PH06_DANRE
V-crk avian sarcoma virus CT10 oncogene homolog-like
Search

CRKL

0.97	CRK like proto-oncogene, adaptor protein (Fragment)

0.77	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.73	GO:0060017	parathyroid gland development
0.69	GO:0009887	animal organ morphogenesis
0.69	GO:0048538	thymus development
0.66	GO:0008284	positive regulation of cell proliferation
0.65	GO:0009952	anterior/posterior pattern specification
0.64	GO:0001568	blood vessel development
0.64	GO:0007507	heart development
0.63	GO:0007520	myoblast fusion
0.57	GO:0048793	pronephros development

0.75	GO:0001784	phosphotyrosine residue binding
0.68	GO:0045296	cadherin binding
0.62	GO:0042802	identical protein binding
0.51	GO:0005070	SH3/SH2 adaptor activity
0.50	GO:0042169	SH2 domain binding
0.49	GO:0046875	ephrin receptor binding
0.48	GO:0043621	protein self-association
0.48	GO:1990782	protein tyrosine kinase binding
0.46	GO:0017124	SH3 domain binding
0.42	GO:0005159	insulin-like growth factor receptor binding

0.59	GO:0005654	nucleoplasm
0.59	GO:0005829	cytosol
0.45	GO:0015629	actin cytoskeleton
0.42	GO:0070062	extracellular exosome
0.40	GO:0098857	membrane microdomain
0.40	GO:0043234	protein complex
0.37	GO:0005768	endosome
0.36	GO:0031463	Cul3-RING ubiquitin ligase complex
0.35	GO:0005886	plasma membrane

sp|Q6PH11|PYM1_DANRE
Partner of Y14 and mago
Search

PYM1

0.94	PYM homolog 1, exon junction complex associated factor

0.85	GO:1903259	exon-exon junction complex disassembly
0.81	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.75	GO:0045727	positive regulation of translation
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0006310	DNA recombination

0.72	GO:0043022	ribosome binding
0.38	GO:0003723	RNA binding
0.36	GO:0005515	protein binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.85	GO:0035145	exon-exon junction complex
0.70	GO:0005730	nucleolus
0.67	GO:0030054	cell junction
0.62	GO:0005829	cytosol
0.51	GO:0005654	nucleoplasm
0.34	GO:0046821	extrachromosomal DNA
0.33	GO:0031226	intrinsic component of plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q6PH17|ATAT_DANRE
Alpha-tubulin N-acetyltransferase 1
Search

ATAT1

0.85	Alpha-tubulin N-acetyltransferase

0.86	GO:0071929	alpha-tubulin acetylation
0.77	GO:0070507	regulation of microtubule cytoskeleton organization
0.72	GO:0048666	neuron development
0.53	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly
0.51	GO:0021542	dentate gyrus development
0.50	GO:0045598	regulation of fat cell differentiation
0.48	GO:0007283	spermatogenesis
0.34	GO:0060271	cilium assembly
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0010467	gene expression

0.86	GO:0019799	tubulin N-acetyltransferase activity
0.55	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
0.42	GO:0050662	coenzyme binding
0.34	GO:0003735	structural constituent of ribosome

0.74	GO:0005925	focal adhesion
0.73	GO:0005874	microtubule
0.73	GO:0005905	clathrin-coated pit
0.72	GO:0030424	axon
0.70	GO:0005819	spindle
0.52	GO:0097427	microtubule bundle
0.46	GO:0005737	cytoplasm
0.39	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:2.3.1.108

GO:0019799

sp|Q6PH18|N2F1B_DANRE
Nuclear receptor subfamily 2 group F member 1-B
Search

0.92	Ovalbumin upstream promoter-transcription factor I

0.80	GO:0030522	intracellular receptor signaling pathway
0.79	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0097659	nucleic acid-templated transcription
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0060838	lymphatic endothelial cell fate commitment
0.54	GO:0010467	gene expression
0.53	GO:0034645	cellular macromolecule biosynthetic process
0.51	GO:0009956	radial pattern formation

0.82	GO:0004879	nuclear receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.51	GO:0001972	retinoic acid binding
0.47	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0042803	protein homodimerization activity
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.43	GO:0003690	double-stranded DNA binding
0.35	GO:0003712	transcription cofactor activity

0.61	GO:0005634	nucleus
0.48	GO:0005829	cytosol
0.48	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q6PH19|GATM_DANRE
Glycine amidinotransferase, mitochondrial
Search

GATM

0.89	LOW QUALITY PROTEIN: glycine amidinotransferase, mitochondrial

0.64	GO:0006601	creatine biosynthetic process
0.61	GO:0014889	muscle atrophy
0.57	GO:0007611	learning or memory
0.50	GO:0007275	multicellular organism development
0.35	GO:0042246	tissue regeneration
0.35	GO:0007584	response to nutrient
0.35	GO:0043434	response to peptide hormone
0.35	GO:0046689	response to mercury ion
0.34	GO:0006979	response to oxidative stress

0.84

GO:0015067

amidinotransferase activity

0.56	GO:0005758	mitochondrial intermembrane space
0.40	GO:0031966	mitochondrial membrane
0.40	GO:0019866	organelle inner membrane
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:2.1.4

GO:0015067

tr|Q6PH25|Q6PH25_DANRE
Vacuolar protein sorting 28 (Yeast)
Search

VPS28

0.85	Vacuolar protein sorting-associated protein 28 homolog

0.80	GO:0032509	endosome transport via multivesicular body sorting pathway
0.79	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
0.78	GO:0045324	late endosome to vacuole transport
0.78	GO:0072666	establishment of protein localization to vacuole
0.65	GO:0006886	intracellular protein transport
0.52	GO:2000395	regulation of ubiquitin-dependent endocytosis
0.49	GO:0031397	negative regulation of protein ubiquitination
0.49	GO:0045807	positive regulation of endocytosis
0.47	GO:0051222	positive regulation of protein transport
0.47	GO:0045732	positive regulation of protein catabolic process

0.48	GO:0043130	ubiquitin binding
0.44	GO:0032403	protein complex binding

0.81	GO:0000813	ESCRT I complex
0.47	GO:0005769	early endosome
0.43	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane
0.37	GO:0031902	late endosome membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0044215	other organism

sp|Q6PH37|ST1S1_DANRE
Cytosolic sulfotransferase 1
Search

0.56	Cytosolic sulfotransferase 1

0.41	GO:0051923	sulfation
0.41	GO:0006805	xenobiotic metabolic process
0.41	GO:0018958	phenol-containing compound metabolic process
0.39	GO:0006068	ethanol catabolic process
0.39	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.38	GO:0042445	hormone metabolic process
0.36	GO:0006575	cellular modified amino acid metabolic process
0.36	GO:0008202	steroid metabolic process
0.34	GO:0009812	flavonoid metabolic process
0.33	GO:0030855	epithelial cell differentiation

0.78

GO:0008146

sulfotransferase activity

0.35	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:2.8.2

GO:0008146

tr|Q6PH45|Q6PH45_DANRE
PRP4 pre-mRNA processing factor 4 homolog (Yeast)
Search

PRPF4

0.95	Pre-mRNA processing factor 4

0.57	GO:0000398	mRNA splicing, via spliceosome
0.56	GO:0060041	retina development in camera-type eye
0.55	GO:0043009	chordate embryonic development

0.66	GO:0030621	U4 snRNA binding
0.64	GO:0017070	U6 snRNA binding

0.83	GO:0071001	U4/U6 snRNP
0.78	GO:0015030	Cajal body
0.76	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.73	GO:0016607	nuclear speck
0.38	GO:0019013	viral nucleocapsid

tr|Q6PH46|Q6PH46_DANRE
T-complex protein 1 subunit delta
Search

CCT4

0.70	T-complex protein 1 subunit delta

0.68	GO:0006457	protein folding
0.57	GO:0090670	RNA localization to Cajal body
0.56	GO:1904869	regulation of protein localization to Cajal body
0.56	GO:1904851	positive regulation of establishment of protein localization to telomere
0.56	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.55	GO:0051973	positive regulation of telomerase activity
0.54	GO:0032212	positive regulation of telomere maintenance via telomerase
0.53	GO:0007339	binding of sperm to zona pellucida
0.53	GO:1900182	positive regulation of protein localization to nucleus
0.51	GO:0050821	protein stabilization

0.71	GO:0051082	unfolded protein binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0044183	protein binding involved in protein folding
0.34	GO:0003723	RNA binding

0.58	GO:0005832	chaperonin-containing T-complex
0.54	GO:0002199	zona pellucida receptor complex
0.51	GO:0005813	centrosome
0.50	GO:0044297	cell body
0.49	GO:0005874	microtubule
0.47	GO:0005654	nucleoplasm
0.40	GO:0042470	melanosome
0.37	GO:0005929	cilium
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|Q6PH52|PCH2_DANRE
Pachytene checkpoint protein 2 homolog
Search

TRIP13

0.94	Pachytene checkpoint protein 2

0.54	GO:0007130	synaptonemal complex assembly
0.54	GO:0007144	female meiosis I
0.53	GO:0001556	oocyte maturation
0.53	GO:0007141	male meiosis I
0.52	GO:0007131	reciprocal meiotic recombination
0.51	GO:0007283	spermatogenesis
0.51	GO:0007094	mitotic spindle assembly checkpoint
0.49	GO:0006302	double-strand break repair
0.34	GO:0006366	transcription by RNA polymerase II
0.33	GO:1903506	regulation of nucleic acid-templated transcription

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0042802	identical protein binding
0.34	GO:0003712	transcription cofactor activity
0.32	GO:0016787	hydrolase activity

0.53	GO:0001673	male germ cell nucleus
0.30	GO:0016020	membrane

0.32

GO:0016787

tr|Q6PH53|Q6PH53_DANRE
Zgc:101121
Search

ZFAND6

0.86	Zinc finger AN1-type containing 6

0.45	GO:0071356	cellular response to tumor necrosis factor
0.45	GO:0010761	fibroblast migration
0.45	GO:0003016	respiratory system process
0.45	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling
0.45	GO:0048745	smooth muscle tissue development
0.44	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.44	GO:0060324	face development
0.44	GO:0043066	negative regulation of apoptotic process
0.43	GO:0048705	skeletal system morphogenesis
0.43	GO:0001701	in utero embryonic development

0.63	GO:0008270	zinc ion binding
0.54	GO:0003677	DNA binding
0.43	GO:0031593	polyubiquitin modification-dependent protein binding

0.34	GO:0005622	intracellular
0.30	GO:0016020	membrane

tr|Q6PH54|Q6PH54_DANRE
Arginase
Search

ARG2

0.57	Mitochondrial arginase-2

0.85	GO:0000050	urea cycle
0.70	GO:0006525	arginine metabolic process
0.59	GO:0071643	regulation of chemokine (C-C motif) ligand 4 production
0.59	GO:1905403	negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process
0.59	GO:1905077	negative regulation of interleukin-17 secretion
0.58	GO:0071641	negative regulation of macrophage inflammatory protein 1 alpha production
0.58	GO:2000666	negative regulation of interleukin-13 secretion
0.58	GO:0071650	negative regulation of chemokine (C-C motif) ligand 5 production
0.58	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation
0.57	GO:1904468	negative regulation of tumor necrosis factor secretion

0.82	GO:0004053	arginase activity
0.54	GO:0046872	metal ion binding
0.35	GO:0050998	nitric-oxide synthase binding
0.34	GO:0003933	GTP cyclohydrolase activity

0.44	GO:0005739	mitochondrion
0.36	GO:0005615	extracellular space
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.82

EC:3.5.3.1

GO:0004053

tr|Q6PH56|Q6PH56_DANRE
Heat shock cognate 70-kd protein, tandem duplicate 3
Search

0.52	Heat shock cognate 70-kd protein, tandem duplicate 3

0.47	GO:0007339	binding of sperm to zona pellucida
0.46	GO:1903955	positive regulation of protein targeting to mitochondrion
0.43	GO:0042026	protein refolding
0.40	GO:0009408	response to heat
0.40	GO:0046686	response to cadmium ion
0.40	GO:0048513	animal organ development
0.38	GO:0001568	blood vessel development
0.38	GO:0002520	immune system development
0.37	GO:0009653	anatomical structure morphogenesis
0.35	GO:0033554	cellular response to stress

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0031625	ubiquitin protein ligase binding
0.44	GO:0031072	heat shock protein binding
0.42	GO:0051082	unfolded protein binding

0.48	GO:0002199	zona pellucida receptor complex
0.45	GO:0044297	cell body
0.45	GO:0008180	COP9 signalosome
0.41	GO:0005829	cytosol
0.35	GO:0072562	blood microparticle
0.34	GO:0043233	organelle lumen
0.33	GO:0044429	mitochondrial part
0.30	GO:0016020	membrane

sp|Q6PH57|GBB1_DANRE
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Search

GNB1

0.91	Guanine nucleotide-binding protein beta subunit

0.61	GO:0007165	signal transduction
0.52	GO:0060041	retina development in camera-type eye
0.51	GO:0050909	sensory perception of taste
0.50	GO:0008283	cell proliferation
0.41	GO:0010659	cardiac muscle cell apoptotic process
0.40	GO:0070208	protein heterotrimerization
0.39	GO:0048920	posterior lateral line neuromast primordium migration
0.39	GO:0071456	cellular response to hypoxia
0.39	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.37	GO:0071380	cellular response to prostaglandin E stimulus

0.50	GO:0032403	protein complex binding
0.48	GO:0051020	GTPase binding
0.46	GO:0003924	GTPase activity
0.41	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity
0.41	GO:0031702	type 1 angiotensin receptor binding
0.40	GO:0030507	spectrin binding
0.38	GO:0004871	signal transducer activity
0.33	GO:0003951	NAD+ kinase activity

0.53	GO:0043209	myelin sheath
0.52	GO:0001750	photoreceptor outer segment
0.52	GO:1905360	GTPase complex
0.51	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.45	GO:0098797	plasma membrane protein complex
0.40	GO:0060170	ciliary membrane
0.40	GO:0001917	photoreceptor inner segment
0.39	GO:0030425	dendrite
0.39	GO:0044297	cell body
0.37	GO:0005765	lysosomal membrane

0.41	EC:3.1.4.39	GO:0047391
0.33	KEGG:R00104	GO:0003951

sp|Q6PH58|TM39A_DANRE
Transmembrane protein 39A
Search

TMEM39A

0.96	Transmembrane protein 39A-A

0.33

GO:0003723

RNA binding

0.30

GO:0044425

membrane part

sp|Q6PH61|S2534_DANRE
Solute carrier family 25 member 34
Search

SLC25A34

0.94	Solute carrier family 25 member 34

0.47	GO:0006839	mitochondrial transport
0.39	GO:0055085	transmembrane transport
0.34	GO:1903527	positive regulation of membrane tubulation
0.34	GO:0032418	lysosome localization
0.34	GO:0007030	Golgi organization
0.33	GO:0032880	regulation of protein localization

0.40	GO:0022857	transmembrane transporter activity
0.34	GO:0019894	kinesin binding

0.46	GO:0005739	mitochondrion
0.42	GO:0019866	organelle inner membrane
0.33	GO:0010008	endosome membrane
0.30	GO:0044425	membrane part

tr|Q6PH62|Q6PH62_DANRE
Cytochrome b-245 light chain
Search

CYBA

0.97	Cytochrome b-245 light chain

0.58	GO:0042554	superoxide anion generation
0.58	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway
0.57	GO:0070257	positive regulation of mucus secretion
0.56	GO:0045730	respiratory burst
0.56	GO:1900426	positive regulation of defense response to bacterium
0.55	GO:0050766	positive regulation of phagocytosis
0.55	GO:1903428	positive regulation of reactive oxygen species biosynthetic process
0.55	GO:0032760	positive regulation of tumor necrosis factor production
0.55	GO:0051279	regulation of release of sequestered calcium ion into cytosol
0.55	GO:0032755	positive regulation of interleukin-6 production

0.62	GO:0020037	heme binding
0.58	GO:0016175	superoxide-generating NADPH oxidase activity
0.52	GO:0017124	SH3 domain binding
0.49	GO:0046982	protein heterodimerization activity
0.49	GO:0046872	metal ion binding
0.44	GO:0009055	electron transfer activity

0.78	GO:0043020	NADPH oxidase complex
0.50	GO:0005768	endosome
0.44	GO:0005739	mitochondrion
0.40	GO:0097038	perinuclear endoplasmic reticulum
0.40	GO:0097517	contractile actin filament bundle
0.40	GO:0042641	actomyosin
0.39	GO:0005925	focal adhesion
0.39	GO:0016324	apical plasma membrane
0.39	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite

0.58

EC:1.6.3

GO:0016175

tr|Q6PH70|Q6PH70_DANRE
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2, like
Search

KDELR2

0.66	ER lumen protein-retaining receptor

0.84	GO:0006621	protein retention in ER lumen
0.65	GO:0015031	protein transport
0.38	GO:0016192	vesicle-mediated transport
0.35	GO:0002369	T cell cytokine production
0.35	GO:0070231	T cell apoptotic process
0.34	GO:0030217	T cell differentiation
0.33	GO:0046907	intracellular transport
0.33	GO:0006629	lipid metabolic process

0.84	GO:0046923	ER retention sequence binding
0.33	GO:0003676	nucleic acid binding
0.32	GO:0016787	hydrolase activity

0.71	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0005801	cis-Golgi network
0.36	GO:0070062	extracellular exosome
0.35	GO:0005794	Golgi apparatus
0.34	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.34	GO:0030133	transport vesicle
0.33	GO:0098588	bounding membrane of organelle
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

tr|Q6PH71|Q6PH71_DANRE
N-acylsphingosine amidohydrolase (acid ceramidase) 1b
Search

ASAH1

0.91	N-acylsphingosine amidohydrolase

0.62	GO:0006629	lipid metabolic process
0.54	GO:0048668	collateral sprouting

0.66

GO:0017040

ceramidase activity

0.78	GO:0005764	lysosome
0.53	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.66

EC:3.5.1.23

GO:0017040

tr|Q6PH73|Q6PH73_DANRE
B-cell translocation gene 1
Search

BTG1

0.96	B-cell translocation protein 1, anti-proliferative

0.74	GO:0008285	negative regulation of cell proliferation
0.53	GO:2000271	positive regulation of fibroblast apoptotic process
0.52	GO:0045603	positive regulation of endothelial cell differentiation
0.51	GO:0045663	positive regulation of myoblast differentiation
0.50	GO:0045766	positive regulation of angiogenesis
0.44	GO:0021542	dentate gyrus development
0.44	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.44	GO:0008213	protein alkylation
0.43	GO:0035914	skeletal muscle cell differentiation
0.43	GO:0008306	associative learning

0.45	GO:0019899	enzyme binding
0.34	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0003712	transcription cofactor activity

0.42	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm

tr|Q6PH75|Q6PH75_DANRE
Cathepsin B
Search

CTSB

0.83	Procathepsin B

0.68	GO:0050790	regulation of catalytic activity
0.61	GO:0006508	proteolysis
0.53	GO:0097067	cellular response to thyroid hormone stimulus
0.53	GO:0030574	collagen catabolic process
0.51	GO:0060429	epithelium development
0.49	GO:0046697	decidualization
0.48	GO:0044257	cellular protein catabolic process
0.46	GO:0030154	cell differentiation
0.45	GO:0031101	fin regeneration
0.44	GO:0051806	entry into cell of other organism involved in symbiotic interaction

0.75	GO:0004197	cysteine-type endopeptidase activity
0.52	GO:0043394	proteoglycan binding
0.51	GO:0005518	collagen binding
0.33	GO:0004252	serine-type endopeptidase activity

0.52	GO:0005764	lysosome
0.49	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0005615	extracellular space
0.47	GO:0005730	nucleolus
0.41	GO:0005739	mitochondrion
0.40	GO:0042470	melanosome
0.35	GO:0031904	endosome lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0005775	vacuolar lumen
0.34	GO:1903561	extracellular vesicle

0.75

EC:3.4.22

GO:0004197

tr|Q6PHC5|Q6PHC5_DANRE
GLI pathogenesis-related 1b
Search

0.81	GLI pathogenesis related 1 like 1

0.61	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

tr|Q6PHC9|Q6PHC9_DANRE
One cut domain family member
Search

ONECUT1

0.79	One cut homeobox 1

0.65	GO:0001889	liver development
0.60	GO:0031018	endocrine pancreas development
0.59	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.59	GO:0001952	regulation of cell-matrix adhesion
0.57	GO:0002064	epithelial cell development
0.57	GO:0030335	positive regulation of cell migration
0.57	GO:0045165	cell fate commitment
0.56	GO:0006351	transcription, DNA-templated
0.56	GO:0060271	cilium assembly
0.56	GO:0045944	positive regulation of transcription by RNA polymerase II

0.59	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.54	GO:0003677	DNA binding
0.53	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0001067	regulatory region nucleic acid binding

0.60	GO:0005634	nucleus
0.45	GO:0015629	actin cytoskeleton
0.43	GO:0043233	organelle lumen
0.40	GO:0044446	intracellular organelle part

tr|Q6PHD4|Q6PHD4_DANRE
La ribonucleoprotein domain family, member 6
Search

LARP6

0.97	La ribonucleoprotein domain family member 6

0.71	GO:0006417	regulation of translation
0.61	GO:0006396	RNA processing
0.57	GO:1902416	positive regulation of mRNA binding
0.56	GO:0010714	positive regulation of collagen metabolic process
0.56	GO:0032965	regulation of collagen biosynthetic process
0.51	GO:0034250	positive regulation of cellular amide metabolic process
0.49	GO:0001756	somitogenesis
0.49	GO:0032270	positive regulation of cellular protein metabolic process
0.48	GO:0010557	positive regulation of macromolecule biosynthetic process
0.48	GO:0031328	positive regulation of cellular biosynthetic process

0.59	GO:0003723	RNA binding
0.54	GO:0017022	myosin binding

0.60	GO:0030529	intracellular ribonucleoprotein complex
0.59	GO:0005634	nucleus
0.49	GO:0019013	viral nucleocapsid
0.32	GO:0005737	cytoplasm

tr|Q6PHD6|Q6PHD6_DANRE
Integrin linked kinase
Search

ILK

0.95	integrin-linked protein kinase

0.72	GO:0007229	integrin-mediated signaling pathway
0.61	GO:0006468	protein phosphorylation
0.60	GO:0034446	substrate adhesion-dependent cell spreading
0.59	GO:0010761	fibroblast migration
0.58	GO:2000178	negative regulation of neural precursor cell proliferation
0.58	GO:0043491	protein kinase B signaling
0.58	GO:0032292	peripheral nervous system axon ensheathment
0.57	GO:0001658	branching involved in ureteric bud morphogenesis
0.57	GO:1901224	positive regulation of NIK/NF-kappaB signaling
0.57	GO:0014044	Schwann cell development

0.62	GO:0004672	protein kinase activity
0.53	GO:0030554	adenyl nucleotide binding
0.53	GO:0019901	protein kinase binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0004871	signal transducer activity
0.39	GO:0005178	integrin binding
0.38	GO:0017124	SH3 domain binding

0.58	GO:0005925	focal adhesion
0.56	GO:0030027	lamellipodium
0.49	GO:0005654	nucleoplasm
0.49	GO:0097517	contractile actin filament bundle
0.49	GO:0042641	actomyosin
0.49	GO:0005829	cytosol
0.45	GO:0030017	sarcomere
0.41	GO:0042383	sarcolemma
0.39	GO:0043034	costamere
0.39	GO:0043198	dendritic shaft

tr|Q6PHD8|Q6PHD8_DANRE
Proliferation-associated 2G4, b
Search

0.73	proliferation-associated protein 2G4

0.38	GO:0045597	positive regulation of cell differentiation
0.38	GO:0043066	negative regulation of apoptotic process
0.37	GO:0045892	negative regulation of transcription, DNA-templated
0.36	GO:0006417	regulation of translation
0.35	GO:0006364	rRNA processing
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0007050	cell cycle arrest
0.34	GO:0008283	cell proliferation
0.34	GO:0006351	transcription, DNA-templated
0.33	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

0.38	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003723	RNA binding
0.34	GO:0003677	DNA binding
0.34	GO:0046872	metal ion binding
0.34	GO:0003735	structural constituent of ribosome
0.33	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0005737	cytoplasm
0.38	GO:0005730	nucleolus
0.36	GO:0070062	extracellular exosome
0.35	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0031983	vesicle lumen
0.34	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.7.10.1

GO:0004714

sp|Q6PHD9|SBP1_DANRE
Selenium-binding protein 1
Search

SELENBP1

0.75	Selenium-binding protein 1

0.39	GO:0015031	protein transport
0.38	GO:0050873	brown fat cell differentiation
0.33	GO:0007165	signal transduction

0.84	GO:0008430	selenium binding
0.33	GO:0005515	protein binding

0.50	GO:0001650	fibrillar center
0.40	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

tr|Q6PHE1|Q6PHE1_DANRE
Lysophosphatidic acid receptor 5a
Search

0.88	Lysophosphatidic acid receptor 5

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0050878	regulation of body fluid levels
0.48	GO:0032501	multicellular organismal process
0.47	GO:0048518	positive regulation of biological process
0.47	GO:0035590	purinergic nucleotide receptor signaling pathway
0.46	GO:0035296	regulation of tube diameter
0.46	GO:0042060	wound healing
0.45	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.45	GO:0051046	regulation of secretion
0.44	GO:0051239	regulation of multicellular organismal process

0.72	GO:0004930	G-protein coupled receptor activity
0.55	GO:0035727	lysophosphatidic acid binding
0.47	GO:0016502	nucleotide receptor activity
0.47	GO:0035586	purinergic receptor activity
0.46	GO:0001653	peptide receptor activity
0.38	GO:0004896	cytokine receptor activity
0.34	GO:0004984	olfactory receptor activity
0.33	GO:0008233	peptidase activity
0.33	GO:0004386	helicase activity
0.32	GO:0030554	adenyl nucleotide binding

0.50	GO:0016604	nuclear body
0.42	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008233

sp|Q6PHE8|CC124_DANRE
Coiled-coil domain-containing protein 124
Search

CCDC124

0.69	Coiled-coil domain-containing protein 124-B

0.44	GO:0051301	cell division
0.44	GO:0007049	cell cycle
0.34	GO:0071804	cellular potassium ion transport
0.33	GO:0098662	inorganic cation transmembrane transport

0.48	GO:0003677	DNA binding
0.36	GO:0003723	RNA binding
0.36	GO:0016286	small conductance calcium-activated potassium channel activity
0.35	GO:0005516	calmodulin binding

0.56	GO:0005829	cytosol
0.52	GO:0005634	nucleus
0.50	GO:0030496	midbody
0.47	GO:0005886	plasma membrane
0.47	GO:0005815	microtubule organizing center
0.30	GO:0031224	intrinsic component of membrane

sp|Q6PHF0|CHM1A_DANRE
Charged multivesicular body protein 1a
Search

CHMP1A

0.97	Charged multivesicular body protein 1a

0.78	GO:0007034	vacuolar transport
0.76	GO:0007076	mitotic chromosome condensation
0.64	GO:0016192	vesicle-mediated transport
0.54	GO:0045014	negative regulation of transcription by glucose
0.54	GO:1901673	regulation of mitotic spindle assembly
0.53	GO:0000920	cell separation after cytokinesis
0.53	GO:0007080	mitotic metaphase plate congression
0.52	GO:0010824	regulation of centrosome duplication
0.51	GO:0006997	nucleus organization
0.50	GO:0016458	gene silencing

0.49	GO:0019904	protein domain specific binding
0.49	GO:0042803	protein homodimerization activity
0.33	GO:0008237	metallopeptidase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0000815	ESCRT III complex
0.78	GO:0016363	nuclear matrix
0.51	GO:0005769	early endosome
0.50	GO:0000794	condensed nuclear chromosome
0.49	GO:0005815	microtubule organizing center
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

tr|Q6PHF1|Q6PHF1_DANRE
Calcium regulated heat stable protein 1
Search

CARHSP1

0.97	Calcium-regulated heat-stable protein 1

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:1903311	regulation of mRNA metabolic process
0.49	GO:0031329	regulation of cellular catabolic process
0.45	GO:0065008	regulation of biological quality
0.34	GO:0019722	calcium-mediated signaling

0.55	GO:0003677	DNA binding
0.54	GO:0003730	mRNA 3'-UTR binding
0.34	GO:0019902	phosphatase binding
0.34	GO:0003950	NAD+ ADP-ribosyltransferase activity

0.52	GO:0043186	P granule
0.52	GO:0000177	cytoplasmic exosome (RNase complex)
0.45	GO:0005829	cytosol
0.37	GO:0000932	P-body
0.36	GO:0070062	extracellular exosome

0.34

EC:2.4.2.30

GO:0003950

sp|Q6PHG2|HEMO_DANRE
Hemopexin
Search

0.94	Warm temperature acclimation protein 65 kDa-1

0.69	GO:0015886	heme transport
0.69	GO:0006879	cellular iron ion homeostasis
0.50	GO:0071391	cellular response to estrogen stimulus
0.39	GO:0007505	adult fat body development
0.39	GO:0007561	imaginal disc eversion
0.38	GO:0097156	fasciculation of motor neuron axon
0.38	GO:0035001	dorsal trunk growth, open tracheal system
0.38	GO:0034769	basement membrane disassembly
0.38	GO:0035159	regulation of tube length, open tracheal system
0.38	GO:0007419	ventral cord development

0.70	GO:0015232	heme transporter activity
0.53	GO:0046872	metal ion binding
0.39	GO:0004222	metalloendopeptidase activity
0.35	GO:0005515	protein binding
0.34	GO:0005044	scavenger receptor activity
0.34	GO:0030247	polysaccharide binding

0.61	GO:0005576	extracellular region
0.37	GO:0030425	dendrite
0.30	GO:0016020	membrane

0.39

GO:0004222

sp|Q6PHG4|LIAS_DANRE
Lipoyl synthase, mitochondrial
Search

LIAS

0.72	Lipoyl synthase, mitochondrial

0.79	GO:0009107	lipoate biosynthetic process
0.75	GO:0009249	protein lipoylation
0.55	GO:0001843	neural tube closure
0.54	GO:0032496	response to lipopolysaccharide
0.53	GO:0006954	inflammatory response
0.49	GO:0006979	response to oxidative stress
0.33	GO:0006260	DNA replication
0.32	GO:0055085	transmembrane transport
0.32	GO:0055114	oxidation-reduction process

0.79	GO:0016992	lipoate synthase activity
0.66	GO:0051539	4 iron, 4 sulfur cluster binding
0.53	GO:0046872	metal ion binding
0.34	GO:0061731	ribonucleoside-diphosphate reductase activity
0.32	GO:0022857	transmembrane transporter activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032553	ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0005739	mitochondrion
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:2.8.1.8

GO:0016992

sp|Q6PHG8|RPA43_DANRE
DNA-directed RNA polymerase I subunit RPA43
Search

TWISTNB

0.97	TWIST neighbor

0.58	GO:0097659	nucleic acid-templated transcription
0.54	GO:0010467	gene expression
0.52	GO:0034645	cellular macromolecule biosynthetic process
0.51	GO:1990823	response to leukemia inhibitory factor
0.48	GO:0071345	cellular response to cytokine stimulus

0.70

GO:0003899

DNA-directed 5'-3' RNA polymerase activity

0.55

GO:0005736

DNA-directed RNA polymerase I complex

0.70

EC:2.7.7.6

GO:0003899

sp|Q6PHH3|PD10A_DANRE
Programmed cell death protein 10-A
Search

PDCD10

0.96	Programmed cell death protein 10-A

0.86	GO:0036481	intrinsic apoptotic signaling pathway in response to hydrogen peroxide
0.86	GO:0090168	Golgi reassembly
0.85	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.85	GO:0051683	establishment of Golgi localization
0.85	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis
0.84	GO:0090505	epiboly involved in wound healing
0.81	GO:0045747	positive regulation of Notch signaling pathway
0.81	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.80	GO:1990830	cellular response to leukemia inhibitory factor
0.80	GO:0032874	positive regulation of stress-activated MAPK cascade

0.81	GO:0047485	protein N-terminus binding
0.75	GO:0019901	protein kinase binding
0.72	GO:0042803	protein homodimerization activity

0.71	GO:0005794	Golgi apparatus
0.66	GO:0005829	cytosol
0.49	GO:0098588	bounding membrane of organelle
0.48	GO:0031984	organelle subcompartment
0.42	GO:0070062	extracellular exosome
0.42	GO:0005886	plasma membrane

tr|Q6PHH5|Q6PHH5_DANRE
Hepatocyte nuclear factor 4, alpha
Search

HNF4A

0.94	Hepatocyte nuclear factor 4 alpha

0.79	GO:0043401	steroid hormone mediated signaling pathway
0.76	GO:0030522	intracellular receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:2000189	positive regulation of cholesterol homeostasis
0.55	GO:0055091	phospholipid homeostasis
0.54	GO:0070328	triglyceride homeostasis
0.53	GO:0010470	regulation of gastrulation

0.80	GO:0003707	steroid hormone receptor activity
0.78	GO:0004879	nuclear receptor activity
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0005504	fatty acid binding
0.53	GO:0001102	RNA polymerase II activating transcription factor binding
0.53	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.51	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.51	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.46	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.38	GO:0005737	cytoplasm

0.35

EC:3.1.2.2

GO:0016290

tr|Q6PHI8|Q6PHI8_DANRE
Tkt protein
Search

TKT

0.43	Transketolase b

0.53	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process
0.48	GO:0040008	regulation of growth
0.36	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.36	GO:0009052	pentose-phosphate shunt, non-oxidative branch
0.35	GO:0005999	xylulose biosynthetic process
0.35	GO:0043085	positive regulation of catalytic activity
0.33	GO:0046390	ribose phosphate biosynthetic process

0.52	GO:0004802	transketolase activity
0.47	GO:0042803	protein homodimerization activity
0.40	GO:0048037	cofactor binding
0.35	GO:0046872	metal ion binding
0.35	GO:0008047	enzyme activator activity
0.34	GO:0048029	monosaccharide binding
0.33	GO:1901681	sulfur compound binding
0.33	GO:0019842	vitamin binding
0.32	GO:0043168	anion binding
0.32	GO:1901363	heterocyclic compound binding

0.50	GO:0043209	myelin sheath
0.49	GO:0016607	nuclear speck
0.36	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.30	GO:0044425	membrane part

0.52

EC:2.2.1.1

GO:0004802

sp|Q6PHI9|RAB4A_DANRE
Ras-related protein Rab-4A
Search

RAB4A

0.97	RAB4A, member RAS oncogene family variant (Fragment)

0.61	GO:0030100	regulation of endocytosis
0.55	GO:0019882	antigen processing and presentation
0.49	GO:0001944	vasculature development
0.49	GO:0015031	protein transport
0.38	GO:0032482	Rab protein signal transduction
0.37	GO:0032781	positive regulation of ATPase activity

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0008565	protein transporter activity
0.38	GO:0035255	ionotropic glutamate receptor binding
0.37	GO:0051117	ATPase binding
0.37	GO:0019905	syntaxin binding
0.37	GO:0001671	ATPase activator activity

0.58	GO:0070062	extracellular exosome
0.57	GO:0005768	endosome
0.57	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0032593	insulin-responsive compartment
0.36	GO:0098794	postsynapse
0.35	GO:0005829	cytosol
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q6PHJ8|Q6PHJ8_DANRE
Myosin, light chain 12, genome duplicate 1
Search

0.94	Myosin regulatory light chain 2, smooth muscle minor

0.47	GO:0008360	regulation of cell shape
0.43	GO:0072659	protein localization to plasma membrane
0.34	GO:0031032	actomyosin structure organization
0.34	GO:0006936	muscle contraction

0.70	GO:0005509	calcium ion binding
0.52	GO:0032036	myosin heavy chain binding
0.44	GO:0035254	glutamate receptor binding
0.35	GO:0030898	actin-dependent ATPase activity
0.34	GO:0051015	actin filament binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0016460	myosin II complex
0.54	GO:0097517	contractile actin filament bundle
0.54	GO:0042641	actomyosin
0.53	GO:0030018	Z disc
0.50	GO:0005903	brush border
0.49	GO:0099738	cell cortex region
0.48	GO:0045177	apical part of cell
0.36	GO:0070062	extracellular exosome
0.35	GO:0097513	myosin II filament
0.33	GO:0005829	cytosol

tr|Q6PHK4|Q6PHK4_DANRE
Serine--pyruvate aminotransferase
Search

0.87	Serine--pyruvate aminotransferase

0.58	GO:0019265	glycine biosynthetic process, by transamination of glyoxylate
0.55	GO:0046724	oxalic acid secretion
0.54	GO:0019448	L-cysteine catabolic process
0.51	GO:0009436	glyoxylate catabolic process
0.49	GO:0007219	Notch signaling pathway
0.49	GO:0042853	L-alanine catabolic process
0.46	GO:0071391	cellular response to estrogen stimulus
0.37	GO:0051591	response to cAMP
0.37	GO:0051384	response to glucocorticoid
0.37	GO:0042866	pyruvate biosynthetic process

0.81	GO:0004760	serine-pyruvate transaminase activity
0.80	GO:0008453	alanine-glyoxylate transaminase activity
0.52	GO:0043621	protein self-association
0.48	GO:0042803	protein homodimerization activity
0.48	GO:0016597	amino acid binding
0.46	GO:0005102	receptor binding
0.44	GO:0070279	vitamin B6 binding
0.42	GO:0050662	coenzyme binding
0.36	GO:0004038	allantoinase activity
0.35	GO:0050897	cobalt ion binding

0.51	GO:0005777	peroxisome
0.51	GO:0031907	microbody lumen
0.38	GO:0005759	mitochondrial matrix
0.30	GO:0031224	intrinsic component of membrane

0.81	EC:2.6.1.51	GO:0004760
0.81	KEGG:R00585	GO:0004760

sp|Q6PHK6|PURB_DANRE
Transcriptional activator protein Pur-beta
Search

PURB

0.94	Transcriptional activator protein Pur-beta-B

0.74	GO:0008283	cell proliferation
0.71	GO:0030154	cell differentiation
0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.49	GO:0042127	regulation of cell proliferation
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.41	GO:0006268	DNA unwinding involved in DNA replication
0.41	GO:0017148	negative regulation of translation
0.39	GO:0007399	nervous system development
0.38	GO:0048522	positive regulation of cellular process
0.37	GO:0006351	transcription, DNA-templated

0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0003677	DNA binding
0.51	GO:0046332	SMAD binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.47	GO:0008134	transcription factor binding
0.45	GO:0003723	RNA binding
0.43	GO:0000900	translation repressor activity, nucleic acid binding
0.33	GO:0015002	heme-copper terminal oxidase activity
0.33	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.52	GO:0005662	DNA replication factor A complex
0.41	GO:0043025	neuronal cell body
0.41	GO:0030425	dendrite
0.35	GO:0005737	cytoplasm
0.33	GO:0031967	organelle envelope
0.33	GO:0000784	nuclear chromosome, telomeric region
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:1.9

GO:0016675

sp|Q6PHL4|NKAI1_DANRE
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1
Search

NKAIN1

0.96	Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

0.45

GO:0002028

regulation of sodium ion transport

0.41

GO:0051117

ATPase binding

0.37	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q6PHV0|Q6PHV0_DANRE
Syntaxin 3A
Search

STX3

0.93	Syntaxin-3

0.86	GO:0016081	synaptic vesicle docking
0.66	GO:0006886	intracellular protein transport
0.65	GO:0061025	membrane fusion
0.52	GO:1903540	establishment of protein localization to postsynaptic membrane
0.52	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels
0.52	GO:2000010	positive regulation of protein localization to cell surface
0.51	GO:0048284	organelle fusion
0.51	GO:0097120	receptor localization to synapse
0.51	GO:0016050	vesicle organization
0.50	GO:1903078	positive regulation of protein localization to plasma membrane

0.77	GO:0005484	SNAP receptor activity
0.46	GO:0000149	SNARE binding
0.40	GO:0050544	arachidonic acid binding
0.34	GO:0008168	methyltransferase activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0003677	DNA binding
0.32	GO:0032555	purine ribonucleotide binding

0.79	GO:0098793	presynapse
0.52	GO:0031201	SNARE complex
0.52	GO:0097470	ribbon synapse
0.52	GO:0042589	zymogen granule membrane
0.52	GO:0070382	exocytic vesicle
0.51	GO:0005766	primary lysosome
0.51	GO:0042581	specific granule
0.50	GO:0042470	melanosome
0.49	GO:0044306	neuron projection terminus
0.49	GO:0016324	apical plasma membrane

0.34

GO:0008168

tr|Q6PHV3|Q6PHV3_DANRE
Stanniocalcin 1
Search

0.97	Stanniocalcin

0.76	GO:0010469	regulation of receptor activity
0.58	GO:0003421	growth plate cartilage axis specification
0.58	GO:1903402	regulation of renal phosphate excretion
0.56	GO:0001886	endothelial cell morphogenesis
0.56	GO:0035988	chondrocyte proliferation
0.56	GO:0055074	calcium ion homeostasis
0.56	GO:0090280	positive regulation of calcium ion import
0.55	GO:0072503	cellular divalent inorganic cation homeostasis
0.55	GO:0086004	regulation of cardiac muscle cell contraction
0.55	GO:0010596	negative regulation of endothelial cell migration

0.79	GO:0005179	hormone activity
0.33	GO:0043565	sequence-specific DNA binding

0.66	GO:0005576	extracellular region
0.44	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.38	GO:0016324	apical plasma membrane
0.34	GO:0097708	intracellular vesicle
0.34	GO:0012505	endomembrane system

tr|Q6PHV5|Q6PHV5_DANRE
Carboxypeptidase A5
Search

CPA1

0.86	Carboxypeptidase A

0.60	GO:0006508	proteolysis
0.34	GO:0044257	cellular protein catabolic process

0.76	GO:0004181	metallocarboxypeptidase activity
0.62	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding

0.50

GO:0005615

extracellular space

0.76

EC:3.4.17

GO:0004181

tr|Q6PHV6|Q6PHV6_DANRE
Serine/threonine kinase 17b (Apoptosis-inducing)
Search

STK17B

0.94	Serine/threonine kinase 17B (apoptosis-inducing)

0.63	GO:0006468	protein phosphorylation
0.60	GO:2000271	positive regulation of fibroblast apoptotic process
0.50	GO:2000377	regulation of reactive oxygen species metabolic process
0.46	GO:0035556	intracellular signal transduction
0.37	GO:0006915	apoptotic process
0.33	GO:0007018	microtubule-based movement

0.66	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003777	microtubule motor activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding

0.48	GO:0016607	nuclear speck
0.40	GO:0005886	plasma membrane
0.36	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.35	GO:0005856	cytoskeleton
0.33	GO:1902494	catalytic complex
0.32	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.66

GO:0004674

tr|Q6PHV8|Q6PHV8_DANRE
RAS, dexamethasone-induced 1
Search

RASD1

0.97	Activator of G-protein signaling 1

0.61	GO:0007165	signal transduction
0.42	GO:0001963	synaptic transmission, dopaminergic
0.40	GO:0007626	locomotory behavior
0.36	GO:0051172	negative regulation of nitrogen compound metabolic process
0.36	GO:0031324	negative regulation of cellular metabolic process
0.36	GO:0010558	negative regulation of macromolecule biosynthetic process
0.36	GO:0010629	negative regulation of gene expression
0.34	GO:0080090	regulation of primary metabolic process
0.34	GO:0043949	regulation of cAMP-mediated signaling
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0031681	G-protein beta-subunit binding
0.34	GO:0043548	phosphatidylinositol 3-kinase binding
0.34	GO:0031624	ubiquitin conjugating enzyme binding

0.52	GO:0016529	sarcoplasmic reticulum
0.37	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005634	nucleus
0.34	GO:0005886	plasma membrane

sp|Q6PHY8|SELTB_DANRE
Selenoprotein T1b
Search

SELENOT

0.96	Selenoprotein T

0.58	GO:0035773	insulin secretion involved in cellular response to glucose stimulus
0.55	GO:0031016	pancreas development
0.48	GO:0045454	cell redox homeostasis
0.43	GO:0060124	positive regulation of growth hormone secretion
0.41	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.40	GO:0098869	cellular oxidant detoxification
0.36	GO:0055114	oxidation-reduction process
0.35	GO:0001514	selenocysteine incorporation
0.32	GO:0035556	intracellular signal transduction

0.43	GO:0004791	thioredoxin-disulfide reductase activity
0.35	GO:0008430	selenium binding
0.33	GO:0005201	extracellular matrix structural constituent

0.49	GO:0005783	endoplasmic reticulum
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.40	GO:0031984	organelle subcompartment
0.33	GO:0005604	basement membrane
0.33	GO:0005581	collagen trimer
0.30	GO:0016021	integral component of membrane

0.43	EC:1.8.1.9	GO:0004791
0.43	KEGG:R02016	GO:0004791

sp|Q6PI20|H33_DANRE
Histone H3.3
Search

0.43	GO:0006334	nucleosome assembly
0.37	GO:0007140	male meiotic nuclear division
0.36	GO:0034724	DNA replication-independent nucleosome organization
0.36	GO:0030307	positive regulation of cell growth

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.45	GO:0031491	nucleosome binding
0.39	GO:0098770	FBXO family protein binding
0.35	GO:0001067	regulatory region nucleic acid binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.37	GO:0005700	polytene chromosome
0.35	GO:0000781	chromosome, telomeric region
0.34	GO:0043233	organelle lumen
0.33	GO:0043234	protein complex

sp|Q6PI52|CALM_DANRE
Calmodulin
Search

0.50	Calmodulin 1 (phosphorylase kinase, delta)

0.41	GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity
0.41	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity
0.40	GO:0005513	detection of calcium ion
0.40	GO:0032516	positive regulation of phosphoprotein phosphatase activity
0.40	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.40	GO:0030819	positive regulation of cAMP biosynthetic process
0.39	GO:0055117	regulation of cardiac muscle contraction
0.39	GO:0002027	regulation of heart rate
0.39	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
0.38	GO:0043388	positive regulation of DNA binding

0.70	GO:0005509	calcium ion binding
0.41	GO:0031997	N-terminal myristoylation domain binding
0.40	GO:0031432	titin binding
0.40	GO:0008179	adenylate cyclase binding
0.40	GO:0072542	protein phosphatase activator activity
0.40	GO:0097718	disordered domain specific binding
0.39	GO:0044325	ion channel binding
0.39	GO:0019855	calcium channel inhibitor activity
0.38	GO:0019901	protein kinase binding
0.36	GO:0016301	kinase activity

0.40	GO:0034703	cation channel complex
0.39	GO:0000922	spindle pole
0.39	GO:0005876	spindle microtubule
0.39	GO:0030017	sarcomere
0.38	GO:0005813	centrosome
0.38	GO:0043209	myelin sheath
0.36	GO:0005887	integral component of plasma membrane
0.35	GO:1902494	catalytic complex
0.35	GO:0043234	protein complex
0.33	GO:0005829	cytosol

tr|Q6PR57|Q6PR57_DANRE
NPY receptor Y7
Search

0.94	Neuropeptide Y receptor type 2

0.79	GO:0007218	neuropeptide signaling pathway
0.49	GO:0003214	cardiac left ventricle morphogenesis
0.48	GO:0003151	outflow tract morphogenesis
0.46	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.41	GO:0007631	feeding behavior
0.40	GO:0007268	chemical synaptic transmission
0.37	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep
0.37	GO:0033603	positive regulation of dopamine secretion
0.37	GO:2000252	negative regulation of feeding behavior
0.37	GO:0051967	negative regulation of synaptic transmission, glutamatergic

0.84	GO:0004983	neuropeptide Y receptor activity
0.49	GO:0042923	neuropeptide binding
0.34	GO:0005246	calcium channel regulator activity
0.33	GO:0005515	protein binding

0.46	GO:0097730	non-motile cilium
0.35	GO:0005886	plasma membrane
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

tr|Q6PSS4|Q6PSS4_DANRE
GABA(A) receptor associated protein
Search

GABARAP

0.97	GABA(A) receptor-associated protein a

0.77	GO:0006914	autophagy
0.51	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors
0.46	GO:0000226	microtubule cytoskeleton organization
0.45	GO:0006995	cellular response to nitrogen starvation
0.45	GO:0061726	mitochondrion disassembly
0.43	GO:0007033	vacuole organization
0.41	GO:0070925	organelle assembly
0.40	GO:0060322	head development
0.40	GO:0007417	central nervous system development
0.39	GO:0048513	animal organ development

0.51	GO:0050811	GABA receptor binding
0.49	GO:0048487	beta-tubulin binding
0.47	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0008017	microtubule binding
0.34	GO:0016791	phosphatase activity
0.32	GO:0046872	metal ion binding

0.52	GO:0000421	autophagosome membrane
0.51	GO:0005790	smooth endoplasmic reticulum
0.51	GO:0097225	sperm midpiece
0.48	GO:0005930	axoneme
0.47	GO:0005764	lysosome
0.46	GO:0005875	microtubule associated complex
0.45	GO:0015629	actin cytoskeleton
0.45	GO:0005794	Golgi apparatus
0.40	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane

0.34

EC:3.1.3 EC:3.1.3.41

GO:0016791

sp|Q6PUF3|DHI1L_DANRE
Hydroxysteroid 11-beta-dehydrogenase 1-like protein
Search

HSD11B1L

0.66	11-beta-hydroxysteroid dehydrogenase long form

0.52	GO:0055114	oxidation-reduction process
0.39	GO:0030324	lung development
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.53	GO:0016491	oxidoreductase activity
0.34	GO:0070403	NAD+ binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0016740	transferase activity

0.44	GO:0005654	nucleoplasm
0.38	GO:0005576	extracellular region
0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.53

GO:0016491

sp|Q6PUR6|GPN2_DANRE
GPN-loop GTPase 2
Search

GPN2

0.92	G patch domain containing 3

0.77	GO:1990022	RNA polymerase III complex localization to nucleus
0.77	GO:0044376	RNA polymerase II complex import to nucleus
0.63	GO:1902182	shoot apical meristem development
0.57	GO:0009658	chloroplast organization
0.57	GO:0009793	embryo development ending in seed dormancy
0.49	GO:0051301	cell division
0.45	GO:0034087	establishment of mitotic sister chromatid cohesion
0.43	GO:0006606	protein import into nucleus

0.59	GO:0003924	GTPase activity
0.48	GO:0032550	purine ribonucleoside binding
0.48	GO:0019001	guanyl nucleotide binding
0.42	GO:0032555	purine ribonucleotide binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003676	nucleic acid binding

0.52	GO:0005874	microtubule
0.44	GO:0005737	cytoplasm

sp|Q6PUR7|SMR8B_DANRE
Smith-Magenis syndrome chromosomal region candidate gene 8-B protein homolog
Search

0.10	Smith-Magenis syndrome chromosomal region candidate gene 8-B protein homolog

0.30	GO:0009987	cellular process
0.30	GO:0031400	negative regulation of protein modification process
0.30	GO:0016239	positive regulation of macroautophagy
0.30	GO:0009967	positive regulation of signal transduction
0.30	GO:0010563	negative regulation of phosphorus metabolic process
0.30	GO:0032006	regulation of TOR signaling
0.30	GO:1902115	regulation of organelle assembly
0.30	GO:1901096	regulation of autophagosome maturation
0.30	GO:0051338	regulation of transferase activity
0.30	GO:0042325	regulation of phosphorylation

0.30	GO:0004860	protein kinase inhibitor activity
0.30	GO:0005515	protein binding

0.30	GO:0043234	protein complex
0.30	GO:1902911	protein kinase complex
0.30	GO:0044464	cell part
0.30	GO:0043227	membrane-bounded organelle

tr|Q6PV84|Q6PV84_DANRE
Zic family member 3 heterotaxy 1 (Odd-paired homolog, Drosophila)
Search

ZIC3

0.97	Zinc finger protein ZIC 3

0.57	GO:0007368	determination of left/right symmetry
0.55	GO:0048513	animal organ development
0.55	GO:0007399	nervous system development
0.55	GO:0009952	anterior/posterior pattern specification
0.52	GO:0009790	embryo development
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.52	GO:0061008	hepaticobiliary system development
0.51	GO:0048565	digestive tract development
0.51	GO:0006366	transcription by RNA polymerase II
0.51	GO:0060562	epithelial tube morphogenesis

0.54	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0031490	chromatin DNA binding
0.36	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding

0.49	GO:0005654	nucleoplasm
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q6PVV8|Q6PVV8_DANRE
SPARC
Search

SPARC

0.96	Secreted protein acidic and rich in cysteine

0.61	GO:0007165	signal transduction
0.56	GO:0001501	skeletal system development
0.54	GO:0001937	negative regulation of endothelial cell proliferation
0.53	GO:0010595	positive regulation of endothelial cell migration
0.53	GO:0016525	negative regulation of angiogenesis
0.52	GO:0043473	pigmentation
0.52	GO:0048513	animal organ development
0.51	GO:0071363	cellular response to growth factor stimulus
0.47	GO:0060037	pharyngeal system development
0.46	GO:0022604	regulation of cell morphogenesis

0.84	GO:0050840	extracellular matrix binding
0.83	GO:0005518	collagen binding
0.70	GO:0005509	calcium ion binding

0.76	GO:0005578	proteinaceous extracellular matrix
0.73	GO:0005615	extracellular space
0.56	GO:0031092	platelet alpha granule membrane
0.53	GO:0016363	nuclear matrix
0.49	GO:0009986	cell surface
0.42	GO:0044420	extracellular matrix component
0.35	GO:0071682	endocytic vesicle lumen
0.35	GO:0031093	platelet alpha granule lumen
0.34	GO:0005739	mitochondrion
0.33	GO:0005886	plasma membrane

tr|Q6PWU7|Q6PWU7_DANRE
Zic family member 6
Search

0.59	Zinc finger protein ZIC

0.54	GO:0007417	central nervous system development
0.52	GO:0048513	animal organ development
0.47	GO:0060322	head development
0.43	GO:0007628	adult walking behavior
0.43	GO:0008589	regulation of smoothened signaling pathway
0.43	GO:0042307	positive regulation of protein import into nucleus
0.42	GO:0007389	pattern specification process
0.42	GO:0045944	positive regulation of transcription by RNA polymerase II
0.42	GO:0006366	transcription by RNA polymerase II
0.39	GO:0009653	anatomical structure morphogenesis

0.51	GO:0003676	nucleic acid binding
0.43	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.41	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.38	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.42	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

tr|Q6Q382|Q6Q382_DANRE
Mitogen-activated protein kinase
Search

NLK

0.58	Mitogen-activated protein kinase

0.77	GO:0000165	MAPK cascade
0.56	GO:0030111	regulation of Wnt signaling pathway
0.54	GO:0018107	peptidyl-threonine phosphorylation
0.53	GO:0042501	serine phosphorylation of STAT protein
0.51	GO:0007179	transforming growth factor beta receptor signaling pathway
0.50	GO:0050821	protein stabilization
0.49	GO:0009968	negative regulation of signal transduction
0.48	GO:0046777	protein autophosphorylation
0.47	GO:0009967	positive regulation of signal transduction
0.47	GO:0007399	nervous system development

0.79	GO:0004707	MAP kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0042169	SH2 domain binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0008134	transcription factor binding
0.42	GO:0000287	magnesium ion binding
0.35	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.33	GO:0016853	isomerase activity

0.44	GO:0005622	intracellular
0.41	GO:0043227	membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.79	EC:2.7.11.24	GO:0004707
0.79	KEGG:R00162	GO:0004707

tr|Q6Q413|Q6Q413_DANRE
Neurofibromin 2b (merlin)
Search

0.78	Neurofibromin 2 (Bilateral acoustic neuroma)

0.54	GO:0014010	Schwann cell proliferation
0.52	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein
0.52	GO:0007398	ectoderm development
0.52	GO:0035330	regulation of hippo signaling
0.52	GO:0070306	lens fiber cell differentiation
0.51	GO:0051496	positive regulation of stress fiber assembly
0.51	GO:0021766	hippocampus development
0.51	GO:0001707	mesoderm formation
0.51	GO:0072091	regulation of stem cell proliferation
0.51	GO:0014013	regulation of gliogenesis

0.71	GO:0008092	cytoskeletal protein binding
0.34	GO:0005178	integrin binding
0.34	GO:0008013	beta-catenin binding
0.34	GO:0019904	protein domain specific binding

0.69	GO:0005856	cytoskeleton
0.51	GO:0097610	cell surface furrow
0.50	GO:0030175	filopodium
0.50	GO:0001726	ruffle
0.50	GO:0030027	lamellipodium
0.49	GO:0032155	cell division site part
0.49	GO:0044297	cell body
0.49	GO:0045177	apical part of cell
0.49	GO:0005769	early endosome
0.48	GO:0005912	adherens junction

sp|Q6Q415|RL36_DANRE
60S ribosomal protein L36
Search

RPL36

0.70	60S ribosomal protein L36 pseudogene

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.43	GO:0007420	brain development
0.42	GO:0051726	regulation of cell cycle
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process

0.63	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.34	GO:0070840	dynein complex binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0008134	transcription factor binding
0.32	GO:0016491	oxidoreductase activity

0.60	GO:0005840	ribosome
0.48	GO:0044445	cytosolic part
0.46	GO:0005844	polysome
0.43	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016491

tr|Q6Q417|Q6Q417_DANRE
Ribosomal protein L7
Search

RPL7

0.71	Ribosomal protein L7

0.42	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.42	GO:0051726	regulation of cell cycle
0.42	GO:0002181	cytoplasmic translation
0.35	GO:0097421	liver regeneration
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.34	GO:0006413	translational initiation

0.40	GO:0003729	mRNA binding
0.40	GO:0042803	protein homodimerization activity
0.38	GO:0003735	structural constituent of ribosome
0.35	GO:0003677	DNA binding
0.34	GO:0008097	5S rRNA binding
0.32	GO:0016787	hydrolase activity

0.57	GO:0005840	ribosome
0.43	GO:0005844	polysome
0.43	GO:0044445	cytosolic part
0.38	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0031672	A band
0.34	GO:0043233	organelle lumen
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.32

GO:0016787

tr|Q6Q419|Q6Q419_DANRE
Ribosomal protein S29
Search

RPS29

0.84	Ribosomal protein S29

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.44	GO:0060218	hematopoietic stem cell differentiation
0.44	GO:0048821	erythrocyte development
0.44	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.44	GO:0001570	vasculogenesis
0.43	GO:0001525	angiogenesis
0.42	GO:0043009	chordate embryonic development

0.64	GO:0003735	structural constituent of ribosome
0.43	GO:0008270	zinc ion binding
0.42	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.48	GO:0044445	cytosolic part
0.46	GO:0005844	polysome
0.45	GO:0044446	intracellular organelle part
0.40	GO:0005791	rough endoplasmic reticulum
0.39	GO:0098562	cytoplasmic side of membrane
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0098588	bounding membrane of organelle
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome

0.32

GO:0016787

tr|Q6Q420|Q6Q420_DANRE
Ribosomal protein S15a
Search

RPS15A

0.74	Ribosomal protein S15a

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.46	GO:0045787	positive regulation of cell cycle
0.46	GO:0008284	positive regulation of cell proliferation
0.45	GO:0009615	response to virus
0.36	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.35	GO:0043009	chordate embryonic development
0.35	GO:0007420	brain development

0.63	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.46	GO:0044445	cytosolic part
0.41	GO:0044446	intracellular organelle part
0.40	GO:0005739	mitochondrion
0.38	GO:0031012	extracellular matrix
0.37	GO:0070062	extracellular exosome
0.34	GO:0043233	organelle lumen
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.32

GO:0016787

tr|Q6Q421|Q6Q421_DANRE
Ribosomal protein S15
Search

RPS15

0.70	Ribosomal protein S15

0.58	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.46	GO:0000028	ribosomal small subunit assembly
0.43	GO:0043009	chordate embryonic development
0.38	GO:0000056	ribosomal small subunit export from nucleus
0.37	GO:0097421	liver regeneration
0.37	GO:0001649	osteoblast differentiation
0.36	GO:0016072	rRNA metabolic process

0.62	GO:0003735	structural constituent of ribosome
0.56	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.67	GO:0015935	small ribosomal subunit
0.44	GO:0022626	cytosolic ribosome
0.36	GO:0005925	focal adhesion
0.36	GO:0005654	nucleoplasm
0.35	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane

tr|Q6Q6F6|Q6Q6F6_DANRE
Estrogen-related receptor alpha
Search

ESRRG

0.90	Estrogen-related nuclear receptor gamma variant 2

0.74	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0048384	retinoic acid receptor signaling pathway
0.55	GO:0006351	transcription, DNA-templated
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:2001141	regulation of RNA biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.48	GO:0051254	positive regulation of RNA metabolic process
0.48	GO:0010557	positive regulation of macromolecule biosynthetic process
0.48	GO:0031328	positive regulation of cellular biosynthetic process
0.41	GO:0051253	negative regulation of RNA metabolic process

0.77	GO:0005496	steroid binding
0.75	GO:0003707	steroid hormone receptor activity
0.61	GO:0043565	sequence-specific DNA binding
0.60	GO:0008270	zinc ion binding
0.58	GO:0003708	retinoic acid receptor activity
0.51	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.45	GO:0019904	protein domain specific binding
0.45	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.58	GO:0005634	nucleus
0.47	GO:0045171	intercellular bridge
0.42	GO:0015630	microtubule cytoskeleton
0.42	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q6Q7X9|KLH31_DANRE
Kelch-like protein 31
Search

KLHL31

0.97	Kelch like family member 31

0.59	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:0006355	regulation of transcription, DNA-templated

0.54

GO:0004842

ubiquitin-protein transferase activity

0.59	GO:0031463	Cul3-RING ubiquitin ligase complex
0.30	GO:0016020	membrane

0.54

GO:0004842

sp|Q6QA33|DH12B_DANRE
Very-long-chain 3-oxoacyl-CoA reductase-B
Search

HSD17B12

0.72	Very-long-chain 3-oxoacyl-CoA reductase-B

0.49	GO:0055114	oxidation-reduction process
0.49	GO:0010811	positive regulation of cell-substrate adhesion
0.47	GO:0030198	extracellular matrix organization
0.45	GO:0008210	estrogen metabolic process
0.42	GO:0006694	steroid biosynthetic process
0.42	GO:0042446	hormone biosynthetic process
0.40	GO:0006633	fatty acid biosynthetic process
0.34	GO:0008209	androgen metabolic process
0.34	GO:0030540	female genitalia development
0.34	GO:0032350	regulation of hormone metabolic process

0.50	GO:0016491	oxidoreductase activity
0.50	GO:0001968	fibronectin binding
0.48	GO:0005518	collagen binding
0.48	GO:0008201	heparin binding
0.32	GO:0003735	structural constituent of ribosome

0.46	GO:0005578	proteinaceous extracellular matrix
0.40	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0045179	apical cortex
0.33	GO:0005739	mitochondrion
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.50

GO:0016491

sp|Q6QB00|HELT_DANRE
Hairy and enhancer of split-related protein helt
Search

HELT

0.97	Helt bHLH transcription factor

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0021858	GABAergic neuron differentiation in basal ganglia
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0001967	suckling behavior
0.53	GO:0035264	multicellular organism growth
0.52	GO:0010259	multicellular organism aging
0.50	GO:0051253	negative regulation of RNA metabolic process
0.50	GO:0007417	central nervous system development

0.68	GO:0046983	protein dimerization activity
0.55	GO:0003677	DNA binding
0.52	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0001067	regulatory region nucleic acid binding
0.48	GO:0042802	identical protein binding
0.34	GO:0008134	transcription factor binding
0.33	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding
0.33	GO:0042826	histone deacetylase binding
0.33	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.33	GO:0000989	transcription factor activity, transcription factor binding

0.61	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.33	GO:0017053	transcriptional repressor complex
0.33	GO:0000785	chromatin
0.32	GO:0070013	intracellular organelle lumen
0.32	GO:1902494	catalytic complex
0.31	GO:0005737	cytoplasm

0.33

EC:1.13.11

GO:0016702

sp|Q6QU75|PITX3_DANRE
Pituitary homeobox 3
Search

0.77	Pituitary homeobox 3

0.69	GO:0007275	multicellular organism development
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0060322	head development
0.51	GO:0003228	atrial cardiac muscle tissue development
0.51	GO:2000288	positive regulation of myoblast proliferation
0.50	GO:0048857	neural nucleus development
0.50	GO:0051145	smooth muscle cell differentiation
0.50	GO:0007520	myoblast fusion

0.64	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.51	GO:0001105	RNA polymerase II transcription coactivator activity
0.51	GO:0001102	RNA polymerase II activating transcription factor binding
0.49	GO:0031490	chromatin DNA binding
0.47	GO:0044212	transcription regulatory region DNA binding
0.46	GO:0003690	double-stranded DNA binding
0.37	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.37	GO:0051219	phosphoprotein binding
0.36	GO:0042803	protein homodimerization activity

0.60	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.37	GO:0005737	cytoplasm
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part

tr|Q6QX43|Q6QX43_DANRE
Glycoprotein hormones alpha chain
Search

CGA

0.93	Glycoprotein hormones alpha chain

0.76	GO:0010469	regulation of receptor activity
0.50	GO:0046884	follicle-stimulating hormone secretion
0.50	GO:0032275	luteinizing hormone secretion
0.49	GO:0006590	thyroid hormone generation
0.48	GO:0030878	thyroid gland development
0.48	GO:0046621	negative regulation of organ growth
0.46	GO:0008406	gonad development
0.46	GO:0048589	developmental growth
0.44	GO:0032870	cellular response to hormone stimulus
0.35	GO:0006702	androgen biosynthetic process

0.79	GO:0005179	hormone activity
0.47	GO:0046982	protein heterodimerization activity
0.34	GO:0008083	growth factor activity

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q6QZN6|DACT1_DANRE
Dapper homolog 1
Search

DACT1

0.97	Dishevelled-binding antagonist of beta-catenin 1

0.85	GO:1904863	regulation of beta-catenin-TCF complex assembly
0.83	GO:0035413	positive regulation of catenin import into nucleus
0.81	GO:0046329	negative regulation of JNK cascade
0.79	GO:0030111	regulation of Wnt signaling pathway
0.78	GO:0032092	positive regulation of protein binding
0.78	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.78	GO:0032091	negative regulation of protein binding
0.76	GO:0021915	neural tube development
0.74	GO:0031333	negative regulation of protein complex assembly
0.74	GO:1903364	positive regulation of cellular protein catabolic process

0.83	GO:0051018	protein kinase A binding
0.82	GO:0008013	beta-catenin binding
0.78	GO:0042826	histone deacetylase binding
0.77	GO:0001085	RNA polymerase II transcription factor binding
0.73	GO:0070097	delta-catenin binding
0.69	GO:0005080	protein kinase C binding

0.82	GO:0030877	beta-catenin destruction complex
0.65	GO:0005654	nucleoplasm
0.40	GO:0045202	synapse
0.40	GO:0030054	cell junction
0.37	GO:0005829	cytosol
0.34	GO:0005739	mitochondrion
0.34	GO:0005770	late endosome
0.32	GO:0005886	plasma membrane

sp|Q6R005|DLG4_DANRE
Disks large homolog 4
Search

DLG4

0.91	Disks large like protein 4

0.75	GO:0097120	receptor localization to synapse
0.74	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.74	GO:0043113	receptor clustering
0.74	GO:2000821	regulation of grooming behavior
0.71	GO:0035641	locomotory exploration behavior
0.71	GO:0071625	vocalization behavior
0.71	GO:0060997	dendritic spine morphogenesis
0.71	GO:0016188	synaptic vesicle maturation
0.71	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.71	GO:0035418	protein localization to synapse

0.82	GO:0035255	ionotropic glutamate receptor binding
0.71	GO:0031812	P2Y1 nucleotide receptor binding
0.69	GO:0097110	scaffold protein binding
0.68	GO:0004385	guanylate kinase activity
0.68	GO:0031697	beta-1 adrenergic receptor binding
0.67	GO:0097109	neuroligin family protein binding
0.67	GO:0031748	D1 dopamine receptor binding
0.67	GO:0008022	protein C-terminus binding
0.65	GO:0033130	acetylcholine receptor binding
0.63	GO:0019900	kinase binding

0.79	GO:0008328	ionotropic glutamate receptor complex
0.76	GO:0014069	postsynaptic density
0.73	GO:0045211	postsynaptic membrane
0.73	GO:0044300	cerebellar mossy fiber
0.72	GO:0044224	juxtaparanode region of axon
0.71	GO:0016323	basolateral plasma membrane
0.70	GO:0060076	excitatory synapse
0.68	GO:0043197	dendritic spine
0.68	GO:0044306	neuron projection terminus
0.66	GO:0030054	cell junction

0.68

EC:2.7.4.8

GO:0004385

sp|Q6R3Q6|BSH_DANRE
Brain-specific homeobox protein homolog
Search

BSX

0.96	Hematopoietically-expressed homeobox protein hhex

0.57	GO:0042755	eating behavior
0.57	GO:0060056	mammary gland involution
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0007626	locomotory behavior
0.50	GO:1902680	positive regulation of RNA biosynthetic process
0.43	GO:0007420	brain development
0.41	GO:0048663	neuron fate commitment
0.36	GO:0006351	transcription, DNA-templated

0.64	GO:0043565	sequence-specific DNA binding
0.45	GO:0003700	DNA binding transcription factor activity
0.36	GO:0001012	RNA polymerase II regulatory region DNA binding
0.35	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding
0.33	GO:0030545	receptor regulator activity

0.61	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q6R5J1|DISP2_DANRE
Protein dispatched homolog 2
Search

DISP1

0.95	Dispatched RND transporter family member 1

0.54	GO:0007225	patched ligand maturation
0.52	GO:0060539	diaphragm development
0.50	GO:0009880	embryonic pattern specification
0.50	GO:0007368	determination of left/right symmetry
0.50	GO:0009953	dorsal/ventral pattern formation
0.43	GO:0042886	amide transport
0.41	GO:0071702	organic substance transport
0.38	GO:0035195	gene silencing by miRNA
0.35	GO:0007224	smoothened signaling pathway
0.35	GO:0070207	protein homotrimerization

0.45	GO:0015197	peptide transporter activity
0.33	GO:0005515	protein binding

0.34	GO:0016323	basolateral plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q6R5J2|DISP1_DANRE
Protein dispatched homolog 1
Search

DISP1

0.97	Dispatched RND transporter family member 1

0.57	GO:0007225	patched ligand maturation
0.54	GO:0060539	diaphragm development
0.52	GO:0009880	embryonic pattern specification
0.52	GO:0007368	determination of left/right symmetry
0.52	GO:0009953	dorsal/ventral pattern formation
0.44	GO:0042886	amide transport
0.43	GO:0071702	organic substance transport
0.37	GO:0007224	smoothened signaling pathway
0.37	GO:0042694	muscle cell fate specification
0.37	GO:0070207	protein homotrimerization

0.47	GO:0015197	peptide transporter activity
0.33	GO:0005515	protein binding

0.36	GO:0016323	basolateral plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q6R8J2|HEG_DANRE
Protein HEG
Search

HEG

0.94	Heart of glass

0.84	GO:0007043	cell-cell junction assembly
0.79	GO:0007507	heart development
0.56	GO:0003017	lymph circulation
0.55	GO:0090271	positive regulation of fibroblast growth factor production
0.54	GO:0048845	venous blood vessel morphogenesis
0.53	GO:0001886	endothelial cell morphogenesis
0.52	GO:0061384	heart trabecula morphogenesis
0.52	GO:0001945	lymph vessel development
0.52	GO:0060415	muscle tissue morphogenesis
0.52	GO:0001570	vasculogenesis

0.68	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.33	GO:0004872	receptor activity
0.32	GO:0004222	metalloendopeptidase activity
0.32	GO:0005201	extracellular matrix structural constituent
0.32	GO:0004713	protein tyrosine kinase activity
0.31	GO:0004871	signal transducer activity
0.31	GO:0003677	DNA binding

0.50	GO:0009897	external side of plasma membrane
0.49	GO:0030054	cell junction
0.38	GO:0005576	extracellular region
0.33	GO:0008305	integrin complex
0.32	GO:0000786	nucleosome
0.31	GO:0005634	nucleus

0.32

GO:0004222

tr|Q6RKB0|Q6RKB0_DANRE
Voltage-dependent L-type calcium channel subunit alpha
Search

CACNA1S

0.73	Voltage-dependent L-type calcium channel subunit alpha

0.77	GO:0034765	regulation of ion transmembrane transport
0.77	GO:0070588	calcium ion transmembrane transport
0.54	GO:0006936	muscle contraction
0.50	GO:0086010	membrane depolarization during action potential
0.41	GO:0071313	cellular response to caffeine
0.38	GO:0070509	calcium ion import
0.38	GO:0002074	extraocular skeletal muscle development
0.38	GO:0043501	skeletal muscle adaptation
0.37	GO:0007520	myoblast fusion
0.37	GO:0048741	skeletal muscle fiber development

0.81	GO:0005245	voltage-gated calcium channel activity
0.53	GO:0005509	calcium ion binding
0.39	GO:0005516	calmodulin binding
0.35	GO:0044325	ion channel binding
0.33	GO:0030506	ankyrin binding
0.33	GO:0051393	alpha-actinin binding
0.31	GO:0016798	hydrolase activity, acting on glycosyl bonds

0.80	GO:0005891	voltage-gated calcium channel complex
0.57	GO:0030315	T-tubule
0.55	GO:0031674	I band
0.37	GO:0016529	sarcoplasmic reticulum
0.34	GO:0005887	integral component of plasma membrane

0.31

EC:3.2

GO:0016798

sp|Q6RVD7|SX21B_DANRE
Transcription factor Sox-21-B
Search

0.92	Transcription factor Sox-21-B

0.50	GO:0048731	system development
0.49	GO:1903506	regulation of nucleic acid-templated transcription
0.49	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.49	GO:0010468	regulation of gene expression
0.45	GO:0060429	epithelium development
0.44	GO:0048863	stem cell differentiation
0.43	GO:0022405	hair cycle process
0.42	GO:0006366	transcription by RNA polymerase II
0.42	GO:0008544	epidermis development
0.42	GO:0072089	stem cell proliferation

0.55	GO:0003677	DNA binding
0.44	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.43	GO:0001067	regulatory region nucleic acid binding

0.61	GO:0005634	nucleus
0.33	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|Q6SJP8|FG17_DANRE
Fibroblast growth factor 17
Search

FGF17

0.62	Fibroblast growth factor

0.82	GO:0008543	fibroblast growth factor receptor signaling pathway
0.75	GO:0010469	regulation of receptor activity
0.50	GO:0008284	positive regulation of cell proliferation
0.49	GO:0007498	mesoderm development
0.48	GO:0030917	midbrain-hindbrain boundary development
0.48	GO:0030916	otic vesicle formation
0.47	GO:0030878	thyroid gland development
0.47	GO:0060037	pharyngeal system development
0.46	GO:0051093	negative regulation of developmental process
0.46	GO:0007492	endoderm development

0.84	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.35	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0004713	protein tyrosine kinase activity

0.65	GO:0005576	extracellular region
0.39	GO:0005764	lysosome
0.30	GO:0031224	intrinsic component of membrane

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

tr|Q6SYZ1|Q6SYZ1_DANRE
Homeodomain protein Hb9
Search

MNX1

0.57	Motor neuron and pancreas homeobox protein 1

0.58	GO:0021520	spinal cord motor neuron cell fate specification
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0031018	endocrine pancreas development
0.52	GO:0035883	enteroendocrine cell differentiation
0.45	GO:0048812	neuron projection morphogenesis
0.40	GO:0061101	neuroendocrine cell differentiation
0.39	GO:0061564	axon development
0.39	GO:0048667	cell morphogenesis involved in neuron differentiation

0.64	GO:0043565	sequence-specific DNA binding
0.39	GO:0003700	DNA binding transcription factor activity
0.33	GO:0008241	peptidyl-dipeptidase activity
0.33	GO:0004180	carboxypeptidase activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0008237	metallopeptidase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.40	GO:0005829	cytosol
0.39	GO:0031974	membrane-enclosed lumen
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

EC:3.4.15

GO:0008241

tr|Q6T937|Q6T937_DANRE
Gremlin
Search

GREM1

0.97	Gremlin 1, DAN family BMP antagonist

0.67	GO:0010469	regulation of receptor activity
0.60	GO:0048263	determination of dorsal identity
0.59	GO:0090291	negative regulation of osteoclast proliferation
0.59	GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis
0.59	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation
0.59	GO:0003257	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
0.59	GO:1900155	negative regulation of bone trabecula formation
0.59	GO:0060676	ureteric bud formation
0.58	GO:1900158	negative regulation of bone mineralization involved in bone maturation
0.58	GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis

0.69	GO:0005125	cytokine activity
0.60	GO:0036122	BMP binding
0.59	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.59	GO:0043184	vascular endothelial growth factor receptor 2 binding
0.52	GO:0042803	protein homodimerization activity
0.41	GO:0008201	heparin binding
0.38	GO:0016015	morphogen activity
0.35	GO:0043395	heparan sulfate proteoglycan binding

0.65	GO:0005615	extracellular space
0.51	GO:0009986	cell surface
0.30	GO:0016020	membrane

sp|Q6T938|FIBP_DANRE
Acidic fibroblast growth factor intracellular-binding protein B
Search

FIBP

0.96	Acidic fibroblast growth factor intracellular-binding protein B

0.38	GO:0070527	platelet aggregation
0.37	GO:0048251	elastic fiber assembly
0.36	GO:0070121	Kupffer's vesicle development
0.35	GO:0060026	convergent extension
0.35	GO:0007368	determination of left/right symmetry
0.35	GO:0060271	cilium assembly
0.35	GO:0008543	fibroblast growth factor receptor signaling pathway
0.34	GO:0006357	regulation of transcription by RNA polymerase II
0.33	GO:0006260	DNA replication

0.85	GO:0017134	fibroblast growth factor binding
0.35	GO:0005509	calcium ion binding
0.33	GO:0003697	single-stranded DNA binding
0.33	GO:0003700	DNA binding transcription factor activity

0.51	GO:0016607	nuclear speck
0.38	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:0012505	endomembrane system
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

tr|Q6TA36|Q6TA36_DANRE
BHLH transcription factor
Search

0.81	BHLH transcription factor

0.55	GO:0006351	transcription, DNA-templated
0.54	GO:0006355	regulation of transcription, DNA-templated
0.47	GO:0007219	Notch signaling pathway
0.47	GO:0035282	segmentation
0.46	GO:0043009	chordate embryonic development
0.46	GO:0007420	brain development
0.45	GO:0060429	epithelium development
0.45	GO:0048646	anatomical structure formation involved in morphogenesis
0.45	GO:0009952	anterior/posterior pattern specification
0.41	GO:2000737	negative regulation of stem cell differentiation

0.68	GO:0046983	protein dimerization activity
0.52	GO:0003677	DNA binding
0.40	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0008134	transcription factor binding
0.34	GO:0001067	regulatory region nucleic acid binding
0.33	GO:0042802	identical protein binding

0.58

GO:0005634

nucleus

tr|Q6TCF5|Q6TCF5_DANRE
Lhb protein
Search

0.96	Gonadotropic hormone LH subunit beta

0.76	GO:0010469	regulation of receptor activity
0.50	GO:2000836	positive regulation of androgen secretion
0.50	GO:2000866	positive regulation of estradiol secretion
0.47	GO:0030728	ovulation
0.46	GO:0001556	oocyte maturation
0.46	GO:0008585	female gonad development
0.45	GO:0007530	sex determination
0.44	GO:0007283	spermatogenesis
0.43	GO:0010628	positive regulation of gene expression
0.39	GO:0009725	response to hormone

0.79	GO:0005179	hormone activity
0.51	GO:0031762	follicle-stimulating hormone receptor binding
0.49	GO:0031775	lutropin-choriogonadotropic hormone receptor binding
0.43	GO:0046982	protein heterodimerization activity

0.66	GO:0005576	extracellular region
0.34	GO:0005796	Golgi lumen
0.33	GO:0031982	vesicle

tr|Q6TCF7|Q6TCF7_DANRE
Follicle stimulating hormone beta-subunit
Search

0.81	Follicle-stimulating hormone beta subunit

0.76	GO:0010469	regulation of receptor activity
0.54	GO:2000836	positive regulation of androgen secretion
0.53	GO:2000866	positive regulation of estradiol secretion
0.46	GO:0008585	female gonad development
0.46	GO:0010628	positive regulation of gene expression
0.45	GO:0007530	sex determination
0.44	GO:0007283	spermatogenesis
0.43	GO:0022412	cellular process involved in reproduction in multicellular organism
0.43	GO:0030728	ovulation
0.42	GO:0071695	anatomical structure maturation

0.79	GO:0005179	hormone activity
0.55	GO:0031762	follicle-stimulating hormone receptor binding
0.49	GO:0031775	lutropin-choriogonadotropic hormone receptor binding
0.43	GO:0046982	protein heterodimerization activity

0.66	GO:0005576	extracellular region
0.34	GO:0005737	cytoplasm

sp|Q6TEL0|MTMR8_DANRE
Myotubularin-related protein 8
Search

MTMR8

0.87	Myotubularin-related protein 8

0.81	GO:0046856	phosphatidylinositol dephosphorylation
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.74	GO:0010506	regulation of autophagy
0.42	GO:0014065	phosphatidylinositol 3-kinase signaling
0.41	GO:0000187	activation of MAPK activity
0.40	GO:0001568	blood vessel development
0.40	GO:0000165	MAPK cascade
0.38	GO:0006661	phosphatidylinositol biosynthetic process
0.37	GO:0031330	negative regulation of cellular catabolic process

0.86	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
0.85	GO:0004438	phosphatidylinositol-3-phosphatase activity
0.75	GO:0004725	protein tyrosine phosphatase activity
0.42	GO:0004708	MAP kinase kinase activity
0.35	GO:0005515	protein binding

0.44	GO:0005635	nuclear envelope
0.36	GO:0005829	cytosol
0.35	GO:0043234	protein complex

0.86

GO:0052629

tr|Q6TEL1|Q6TEL1_DANRE
RAD21 cohesin complex component a
Search

RAD21

0.86	Double-strand-break repair protein rad21

0.58	GO:0045876	positive regulation of sister chromatid cohesion
0.57	GO:0071168	protein localization to chromatin
0.53	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle
0.52	GO:0045841	negative regulation of mitotic metaphase/anaphase transition
0.51	GO:0006357	regulation of transcription by RNA polymerase II
0.50	GO:0051173	positive regulation of nitrogen compound metabolic process
0.50	GO:0010604	positive regulation of macromolecule metabolic process
0.50	GO:0031325	positive regulation of cellular metabolic process
0.49	GO:0007062	sister chromatid cohesion
0.49	GO:0006366	transcription by RNA polymerase II

0.51	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.49	GO:0032403	protein complex binding
0.46	GO:0003682	chromatin binding
0.39	GO:0043565	sequence-specific DNA binding

0.69	GO:0000228	nuclear chromosome
0.57	GO:0008278	cohesin complex
0.55	GO:0016363	nuclear matrix
0.48	GO:0005654	nucleoplasm
0.48	GO:0000785	chromatin
0.38	GO:0000775	chromosome, centromeric region
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|Q6TEL2|Q6TEL2_DANRE
KIAA0669-like protein
Search

0.69	TSC22 domain family member 2

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.41	GO:0006970	response to osmotic stress

0.61

GO:0003700

DNA binding transcription factor activity

0.40	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm

sp|Q6TEL3|C42S1_DANRE
CDC42 small effector protein 1
Search

CDC42SE1

0.96	CDC42 small effector protein 1-B

0.57	GO:0009966	regulation of signal transduction
0.50	GO:0021555	midbrain-hindbrain boundary morphogenesis
0.49	GO:0007165	signal transduction
0.48	GO:0008360	regulation of cell shape
0.47	GO:0006909	phagocytosis
0.38	GO:0034260	negative regulation of GTPase activity
0.37	GO:0080135	regulation of cellular response to stress
0.36	GO:0001933	negative regulation of protein phosphorylation
0.36	GO:0023057	negative regulation of signaling
0.36	GO:0010648	negative regulation of cell communication

0.56	GO:0005198	structural molecule activity
0.38	GO:0005095	GTPase inhibitor activity
0.34	GO:0005515	protein binding

0.55	GO:0005886	plasma membrane
0.48	GO:0005856	cytoskeleton
0.39	GO:0042995	cell projection
0.39	GO:0005737	cytoplasm
0.38	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part

tr|Q6TEM2|Q6TEM2_DANRE
Inhibitor of growth protein
Search

ING3

0.71	Inhibitor of growth protein 3

0.71	GO:0016569	covalent chromatin modification
0.54	GO:0043065	positive regulation of apoptotic process
0.54	GO:0018393	internal peptidyl-lysine acetylation
0.40	GO:0040008	regulation of growth
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression

0.56	GO:0140034	methylation-dependent protein binding
0.55	GO:0004402	histone acetyltransferase activity
0.54	GO:0042393	histone binding
0.52	GO:0046872	metal ion binding

0.82	GO:0000812	Swr1 complex
0.78	GO:0035267	NuA4 histone acetyltransferase complex

0.55

GO:0004402

sp|Q6TEM9|MYLIA_DANRE
E3 ubiquitin-protein ligase MYLIP-A
Search

MYLIP

0.93	Myosin regulatory light chain interacting protein a

0.71	GO:0010989	negative regulation of low-density lipoprotein particle clearance
0.70	GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process
0.67	GO:0010977	negative regulation of neuron projection development
0.66	GO:0031648	protein destabilization
0.65	GO:0042632	cholesterol homeostasis
0.65	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.62	GO:0045732	positive regulation of protein catabolic process
0.53	GO:0030178	negative regulation of Wnt signaling pathway
0.53	GO:0007369	gastrulation
0.52	GO:0031032	actomyosin structure organization

0.62	GO:0061630	ubiquitin protein ligase activity
0.60	GO:0008092	cytoskeletal protein binding
0.50	GO:0005200	structural constituent of cytoskeleton

0.69	GO:0005856	cytoskeleton
0.38	GO:0005737	cytoplasm

sp|Q6TEN1|RAP1B_DANRE
Ras-related protein Rap-1b
Search

RAP1B

0.90	Ras-related protein Rap-1b

0.59	GO:0007165	signal transduction
0.50	GO:0061028	establishment of endothelial barrier
0.50	GO:0071320	cellular response to cAMP
0.49	GO:1901888	regulation of cell junction assembly
0.49	GO:2000301	negative regulation of synaptic vesicle exocytosis
0.46	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.43	GO:2000114	regulation of establishment of cell polarity
0.42	GO:2001214	positive regulation of vasculogenesis
0.41	GO:0008283	cell proliferation
0.41	GO:0030033	microvillus assembly

0.65	GO:0003924	GTPase activity
0.63	GO:0005525	GTP binding
0.46	GO:0019003	GDP binding
0.44	GO:0032403	protein complex binding
0.40	GO:0017034	Rap guanyl-nucleotide exchange factor activity
0.38	GO:0008565	protein transporter activity
0.35	GO:0004708	MAP kinase kinase activity

0.47	GO:0030054	cell junction
0.44	GO:0005829	cytosol
0.44	GO:0005811	lipid droplet
0.42	GO:0070062	extracellular exosome
0.41	GO:0032045	guanyl-nucleotide exchange factor complex
0.40	GO:0043209	myelin sheath
0.39	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005886	plasma membrane
0.39	GO:0043005	neuron projection
0.39	GO:0005770	late endosome

0.35

GO:0004708

tr|Q6TEN5|Q6TEN5_DANRE
SRY (sex determining region Y)-box 7
Search

SOX7

0.91	SRY-box containing gene 7

0.51	GO:0001706	endoderm formation
0.51	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.50	GO:0060828	regulation of canonical Wnt signaling pathway
0.49	GO:0008285	negative regulation of cell proliferation
0.46	GO:0045893	positive regulation of transcription, DNA-templated
0.46	GO:0045892	negative regulation of transcription, DNA-templated
0.45	GO:0006357	regulation of transcription by RNA polymerase II

0.55	GO:0003677	DNA binding
0.51	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.47	GO:0001067	regulatory region nucleic acid binding

0.61	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm

sp|Q6TEN6|WDR91_DANRE
WD repeat-containing protein 91
Search

WDR91

0.96	WD repeat-containing protein 91

0.85	GO:0045022	early endosome to late endosome transport
0.82	GO:0043551	regulation of phosphatidylinositol 3-kinase activity
0.73	GO:1903362	regulation of cellular protein catabolic process
0.45	GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining
0.38	GO:0006511	ubiquitin-dependent protein catabolic process

0.84	GO:0035014	phosphatidylinositol 3-kinase regulator activity
0.34	GO:0005515	protein binding

0.85	GO:0031313	extrinsic component of endosome membrane
0.82	GO:0031901	early endosome membrane
0.80	GO:0031902	late endosome membrane
0.66	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q6TEP1|F91A1_DANRE
Protein FAM91A1
Search

sp|Q6TEQ0|EEPD1_DANRE
Endonuclease/exonuclease/phosphatase family domain-containing protein 1
Search

EEPD1

0.97	Endonuclease/exonuclease/phosphatase family domain-containing protein 1

0.63	GO:0006281	DNA repair
0.56	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.60	GO:0004527	exonuclease activity
0.58	GO:0004519	endonuclease activity
0.53	GO:0003677	DNA binding

0.30

GO:0031224

intrinsic component of membrane

tr|Q6TGI4|Q6TGI4_DANRE
POU domain protein
Search

PIT-1

0.67	Pituitary-specific positive transcription factor 1

0.70	GO:0045944	positive regulation of transcription by RNA polymerase II
0.57	GO:0060133	somatotropin secreting cell development
0.56	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process
0.55	GO:0001708	cell fate specification
0.55	GO:0006351	transcription, DNA-templated
0.54	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.53	GO:0040018	positive regulation of multicellular organism growth
0.53	GO:0030183	B cell differentiation
0.52	GO:0008340	determination of adult lifespan
0.50	GO:0051169	nuclear transport

0.68	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.61	GO:0043565	sequence-specific DNA binding
0.54	GO:0044212	transcription regulatory region DNA binding
0.53	GO:0001105	RNA polymerase II transcription coactivator activity
0.53	GO:0001102	RNA polymerase II activating transcription factor binding
0.52	GO:0003690	double-stranded DNA binding
0.51	GO:0003714	transcription corepressor activity
0.49	GO:0003682	chromatin binding

0.60	GO:0005634	nucleus
0.48	GO:0005667	transcription factor complex

tr|Q6TGR5|Q6TGR5_DANRE
Phosphatase and tensin homolog B
Search

0.81	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

0.85	GO:0051895	negative regulation of focal adhesion assembly
0.84	GO:0051898	negative regulation of protein kinase B signaling
0.80	GO:0030336	negative regulation of cell migration
0.79	GO:0046856	phosphatidylinositol dephosphorylation
0.78	GO:0046855	inositol phosphate dephosphorylation
0.77	GO:0008285	negative regulation of cell proliferation
0.77	GO:0031647	regulation of protein stability
0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.53	GO:0001568	blood vessel development
0.53	GO:0051093	negative regulation of developmental process

0.86	GO:0051800	phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
0.86	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
0.83	GO:0030165	PDZ domain binding
0.79	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.75	GO:0004725	protein tyrosine phosphatase activity
0.63	GO:0000287	magnesium ion binding
0.53	GO:0051717	inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
0.50	GO:1990381	ubiquitin-specific protease binding
0.50	GO:0004438	phosphatidylinositol-3-phosphatase activity
0.50	GO:0042577	lipid phosphatase activity

0.51	GO:0035749	myelin sheath adaxonal region
0.50	GO:0043220	Schmidt-Lanterman incisure
0.47	GO:0016324	apical plasma membrane
0.46	GO:0043005	neuron projection
0.46	GO:0009898	cytoplasmic side of plasma membrane
0.44	GO:0005654	nucleoplasm
0.43	GO:0005829	cytosol
0.37	GO:0036477	somatodendritic compartment
0.37	GO:0045211	postsynaptic membrane
0.37	GO:0120038	plasma membrane bounded cell projection part

0.86

EC:3.1.3.67

GO:0016314

tr|Q6TGS5|Q6TGS5_DANRE
Tubulin alpha chain
Search

0.53	Tubulin alpha chain

0.71	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.34	GO:0030705	cytoskeleton-dependent intracellular transport
0.33	GO:0051301	cell division

0.77	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.73	GO:0005874	microtubule
0.46	GO:0005737	cytoplasm
0.34	GO:0044441	ciliary part
0.34	GO:0031982	vesicle
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q6TGS6|SYYC_DANRE
Tyrosine--tRNA ligase, cytoplasmic
Search

YARS

0.51	Tyrosine--tRNA ligase

0.78	GO:0006437	tyrosyl-tRNA aminoacylation
0.44	GO:0010758	regulation of macrophage chemotaxis
0.43	GO:0050918	positive chemotaxis
0.34	GO:0006915	apoptotic process
0.34	GO:0030154	cell differentiation
0.34	GO:0051716	cellular response to stimulus
0.33	GO:0006950	response to stress
0.33	GO:0023052	signaling
0.33	GO:0007154	cell communication

0.79	GO:0004831	tyrosine-tRNA ligase activity
0.67	GO:0000049	tRNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0042056	chemoattractant activity
0.35	GO:0005153	interleukin-8 receptor binding
0.33	GO:0004871	signal transducer activity
0.32	GO:0046872	metal ion binding

0.52	GO:0016604	nuclear body
0.49	GO:0017102	methionyl glutamyl tRNA synthetase complex
0.49	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
0.47	GO:0005829	cytosol
0.41	GO:0005615	extracellular space

0.79	EC:6.1.1.1	GO:0004831
0.79	KEGG:R02918	GO:0004831

tr|Q6TGS9|Q6TGS9_DANRE
Ubiquitin-like 3
Search

0.81	Ubiquitin-like protein 3

0.66	GO:0070062	extracellular exosome
0.56	GO:0005886	plasma membrane
0.43	GO:0005622	intracellular

tr|Q6TGT3|Q6TGT3_DANRE
Dynein, light chain, Tctex-type 3
Search

DYNLT3

0.89	Dynein light chain Tctex-type 3

0.63	GO:0019060	intracellular transport of viral protein in host cell
0.47	GO:0007346	regulation of mitotic cell cycle
0.46	GO:0051301	cell division
0.46	GO:0007049	cell cycle
0.45	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.45	GO:0050768	negative regulation of neurogenesis
0.45	GO:1905709	negative regulation of membrane permeability
0.45	GO:0030010	establishment of cell polarity
0.45	GO:0035022	positive regulation of Rac protein signal transduction
0.44	GO:0051656	establishment of organelle localization

0.72	GO:0042802	identical protein binding
0.49	GO:0003774	motor activity
0.42	GO:0008022	protein C-terminus binding

0.83	GO:0005868	cytoplasmic dynein complex
0.70	GO:0000776	kinetochore
0.62	GO:0005881	cytoplasmic microtubule
0.57	GO:0099503	secretory vesicle
0.49	GO:0044217	other organism part
0.49	GO:0018995	host
0.47	GO:0005819	spindle
0.47	GO:0000779	condensed chromosome, centromeric region
0.44	GO:0044295	axonal growth cone
0.42	GO:0030027	lamellipodium

tr|Q6TGT7|Q6TGT7_DANRE
SH3-domain GRB2-like 3
Search

SH3GL1

0.83	SH3 domain containing GRB2 like 3, endophilin A3

0.71	GO:0006897	endocytosis
0.52	GO:0072318	clathrin coat disassembly
0.50	GO:0036465	synaptic vesicle recycling
0.49	GO:0099003	vesicle-mediated transport in synapse
0.46	GO:0072554	blood vessel lumenization
0.37	GO:1900242	regulation of synaptic vesicle endocytosis
0.37	GO:0098815	modulation of excitatory postsynaptic potential
0.35	GO:0016055	Wnt signaling pathway

0.50	GO:0042802	identical protein binding
0.49	GO:0045296	cadherin binding
0.39	GO:0008022	protein C-terminus binding
0.39	GO:0008289	lipid binding
0.37	GO:0031697	beta-1 adrenergic receptor binding
0.36	GO:0044325	ion channel binding
0.36	GO:0019902	phosphatase binding
0.36	GO:0017124	SH3 domain binding
0.35	GO:0051020	GTPase binding
0.35	GO:0004888	transmembrane signaling receptor activity

0.49	GO:0005737	cytoplasm
0.46	GO:0045202	synapse
0.40	GO:0002102	podosome
0.40	GO:0097708	intracellular vesicle
0.39	GO:0098805	whole membrane
0.39	GO:0012505	endomembrane system
0.38	GO:0098588	bounding membrane of organelle
0.38	GO:0030054	cell junction
0.37	GO:0042995	cell projection
0.35	GO:0070062	extracellular exosome

tr|Q6TGT9|Q6TGT9_DANRE
Serine/arginine-rich-splicing factor 5a
Search

SRSF5

0.86	Serine and arginine rich splicing factor 5

0.37	GO:0097421	liver regeneration
0.37	GO:0033120	positive regulation of RNA splicing
0.37	GO:0032869	cellular response to insulin stimulus
0.35	GO:0051726	regulation of cell cycle
0.35	GO:0006369	termination of RNA polymerase II transcription
0.35	GO:0006376	mRNA splice site selection
0.35	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0031124	mRNA 3'-end processing
0.34	GO:0051028	mRNA transport
0.34	GO:0006405	RNA export from nucleus

0.57	GO:0003723	RNA binding
0.37	GO:0043422	protein kinase B binding

0.46	GO:0005730	nucleolus
0.44	GO:0005829	cytosol
0.34	GO:0016607	nuclear speck

sp|Q6TGU2|SEH1_DANRE
Nucleoporin seh1
Search

SEH1L

0.86	LOW QUALITY PROTEIN: nucleoporin SEH1

0.84	GO:1904263	positive regulation of TORC1 signaling
0.65	GO:0015031	protein transport
0.55	GO:0051315	attachment of mitotic spindle microtubules to kinetochore
0.55	GO:0002534	cytokine production involved in inflammatory response
0.54	GO:0006999	nuclear pore organization
0.51	GO:0034198	cellular response to amino acid starvation
0.51	GO:0050830	defense response to Gram-positive bacterium
0.50	GO:0034629	cellular protein complex localization
0.41	GO:0051028	mRNA transport
0.39	GO:0051301	cell division

0.80	GO:0017056	structural constituent of nuclear pore
0.36	GO:0019902	phosphatase binding

0.53	GO:0031080	nuclear pore outer ring
0.52	GO:0005765	lysosomal membrane
0.52	GO:0061700	GATOR2 complex
0.51	GO:0000776	kinetochore
0.42	GO:0000779	condensed chromosome, centromeric region
0.36	GO:0000242	pericentriolar material
0.35	GO:0005829	cytosol
0.33	GO:0043657	host cell
0.30	GO:0016021	integral component of membrane

tr|Q6TGV2|Q6TGV2_DANRE
RAB22A, member RAS oncogene family
Search

RAB22A

0.96	Ras-related protein Rab-31

0.57	GO:0097494	regulation of vesicle size
0.53	GO:0007032	endosome organization
0.53	GO:0006897	endocytosis
0.47	GO:0043001	Golgi to plasma membrane protein transport
0.47	GO:0090382	phagosome maturation
0.46	GO:0032869	cellular response to insulin stimulus
0.45	GO:0045055	regulated exocytosis
0.45	GO:0043112	receptor metabolic process
0.34	GO:0002283	neutrophil activation involved in immune response
0.34	GO:0002446	neutrophil mediated immunity

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.33	GO:0015035	protein disulfide oxidoreductase activity

0.58	GO:0045335	phagocytic vesicle
0.58	GO:0005769	early endosome
0.49	GO:0015629	actin cytoskeleton
0.47	GO:0032588	trans-Golgi network membrane
0.41	GO:0005886	plasma membrane
0.40	GO:0030666	endocytic vesicle membrane
0.38	GO:0005770	late endosome
0.37	GO:0010008	endosome membrane
0.37	GO:0001726	ruffle
0.37	GO:0070062	extracellular exosome

tr|Q6TGV5|Q6TGV5_DANRE
Gankyrin
Search

PSMD10

0.85	Ankyrin repeat domain-containing protein 16

0.56	GO:0007253	cytoplasmic sequestering of NF-kappaB
0.55	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.54	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
0.53	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.53	GO:0070682	proteasome regulatory particle assembly
0.53	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.53	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.52	GO:0030307	positive regulation of cell growth
0.52	GO:0043409	negative regulation of MAPK cascade
0.51	GO:0031398	positive regulation of protein ubiquitination

0.48

GO:0008134

transcription factor binding

0.69	GO:1905369	endopeptidase complex
0.57	GO:0043234	protein complex
0.50	GO:0045111	intermediate filament cytoskeleton
0.46	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

tr|Q6TGV6|Q6TGV6_DANRE
Proteasome subunit alpha type
Search

PSMA5

0.48	Proteasome endopeptidase complex

0.76	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0045595	regulation of cell differentiation
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0051005	negative regulation of lipoprotein lipase activity
0.35	GO:0038180	nerve growth factor signaling pathway

0.77	GO:0004298	threonine-type endopeptidase activity
0.35	GO:0030379	neurotensin receptor activity, non-G-protein coupled
0.35	GO:0010465	nerve growth factor receptor activity
0.35	GO:0048406	nerve growth factor binding
0.33	GO:0019899	enzyme binding

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.58	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.35	GO:0012505	endomembrane system
0.35	GO:0031983	vesicle lumen
0.35	GO:0097708	intracellular vesicle
0.34	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0098589	membrane region

0.77

GO:0004298

sp|Q6TGV7|ABRAL_DANRE
Costars family protein ABRACL
Search

ABRACL

0.97	Costars family protein ABRACL

0.65	GO:0031288	sorocarp morphogenesis
0.57	GO:2000145	regulation of cell motility
0.57	GO:0032970	regulation of actin filament-based process

0.64

GO:0031143

pseudopodium

sp|Q6TGW5|OSTF1_DANRE
Osteoclast-stimulating factor 1
Search

OSTF1

0.96	Osteoclast-stimulating factor 1

0.40	GO:0043312	neutrophil degranulation
0.39	GO:0001503	ossification
0.35	GO:0007059	chromosome segregation
0.35	GO:0007165	signal transduction
0.35	GO:0051301	cell division
0.34	GO:0006897	endocytosis

0.75	GO:0017124	SH3 domain binding
0.36	GO:0008017	microtubule binding

0.64	GO:0005576	extracellular region
0.40	GO:1904813	ficolin-1-rich granule lumen
0.40	GO:0034774	secretory granule lumen
0.30	GO:0016020	membrane

tr|Q6TGW9|Q6TGW9_DANRE
Nei endonuclease VIII-like 1
Search

NEIL1

0.92	Nei like DNA glycosylase 1

0.72	GO:0006289	nucleotide-excision repair
0.70	GO:0006284	base-excision repair
0.54	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.52	GO:0032074	negative regulation of nuclease activity
0.47	GO:0006979	response to oxidative stress
0.35	GO:0009223	pyrimidine deoxyribonucleotide catabolic process
0.34	GO:0006304	DNA modification

0.77	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity
0.73	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds
0.73	GO:0003684	damaged DNA binding
0.63	GO:0008270	zinc ion binding
0.56	GO:0004519	endonuclease activity
0.52	GO:0008022	protein C-terminus binding

0.46	GO:0005654	nucleoplasm
0.38	GO:0005737	cytoplasm
0.35	GO:0005815	microtubule organizing center
0.34	GO:0005694	chromosome

0.77

EC:4.2.99.18

GO:0003906

tr|Q6TGX5|Q6TGX5_DANRE
F-box and leucine-rich repeat protein 14a
Search

FBXL14

0.85	F-box and leucine rich repeat protein 14

0.68	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.40	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.38	GO:0000209	protein polyubiquitination
0.38	GO:0043687	post-translational protein modification

0.65	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0005515	protein binding

0.66	GO:0019005	SCF ubiquitin ligase complex
0.44	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0004842

tr|Q6TGX7|Q6TGX7_DANRE
Methyl-CpG binding domain protein 3
Search

0.86	Methyl-CpG binding domain protein 3

0.60	GO:0006346	methylation-dependent chromatin silencing
0.54	GO:0000122	negative regulation of transcription by RNA polymerase II
0.49	GO:0016573	histone acetylation
0.49	GO:0001701	in utero embryonic development
0.48	GO:0009888	tissue development
0.46	GO:0042711	maternal behavior
0.44	GO:0030177	positive regulation of Wnt signaling pathway
0.42	GO:0042127	regulation of cell proliferation
0.41	GO:0043623	cellular protein complex assembly
0.40	GO:0060216	definitive hemopoiesis

0.84	GO:0008327	methyl-CpG binding
0.52	GO:0003682	chromatin binding
0.46	GO:0070742	C2H2 zinc finger domain binding
0.45	GO:0035197	siRNA binding
0.42	GO:0003729	mRNA binding
0.37	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.36	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0044877	macromolecular complex binding
0.35	GO:0003696	satellite DNA binding
0.35	GO:0004407	histone deacetylase activity

0.80	GO:0090545	CHD-type complex
0.78	GO:0090568	nuclear transcriptional repressor complex
0.78	GO:0000118	histone deacetylase complex
0.54	GO:0000792	heterochromatin
0.42	GO:0043234	protein complex
0.40	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.35

GO:0004407

tr|Q6TGY0|Q6TGY0_DANRE
HSPC038 protein
Search

ZNF706

0.97	Zinc finger protein 706

0.86	GO:1902455	negative regulation of stem cell population maintenance
0.69	GO:0045892	negative regulation of transcription, DNA-templated
0.42	GO:0006417	regulation of translation

0.40	GO:0019904	protein domain specific binding
0.37	GO:0046872	metal ion binding

0.59	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|Q6TGY6|Q6TGY6_DANRE
Polyadenylate-binding protein
Search

0.60	Polyadenylate-binding protein (Fragment)

0.46	GO:0048096	chromatin-mediated maintenance of transcription
0.46	GO:0001556	oocyte maturation
0.45	GO:0051647	nucleus localization
0.44	GO:0006378	mRNA polyadenylation
0.37	GO:0061013	regulation of mRNA catabolic process
0.36	GO:0045070	positive regulation of viral genome replication
0.36	GO:1902369	negative regulation of RNA catabolic process
0.35	GO:0061515	myeloid cell development
0.35	GO:0043487	regulation of RNA stability
0.35	GO:1903312	negative regulation of mRNA metabolic process

0.58	GO:0003723	RNA binding
0.36	GO:0005515	protein binding

0.48	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.37	GO:0035770	ribonucleoprotein granule
0.35	GO:0071013	catalytic step 2 spliceosome

sp|Q6TGY8|EMC2_DANRE
ER membrane protein complex subunit 2
Search

EMC2

0.94	ER membrane protein complex subunit 2

0.68

GO:0034975

protein folding in endoplasmic reticulum

0.36

GO:0005515

protein binding

0.83	GO:0072546	ER membrane protein complex
0.57	GO:0005739	mitochondrion
0.45	GO:0005634	nucleus

sp|Q6TGZ4|THA11_DANRE
THAP domain-containing protein 11
Search

THAP11

0.85	THAP domain-containing protein 11

0.55	GO:0000122	negative regulation of transcription by RNA polymerase II
0.38	GO:0006351	transcription, DNA-templated

0.59	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.49	GO:0008270	zinc ion binding
0.34	GO:0005515	protein binding

0.59	GO:0045171	intercellular bridge
0.51	GO:0005654	nucleoplasm
0.34	GO:0005737	cytoplasm

sp|Q6TGZ5|HPPD_DANRE
4-hydroxyphenylpyruvate dioxygenase
Search

HPD

0.59	4-hydroxyphenylpyruvate dioxygenase

0.68	GO:0009072	aromatic amino acid family metabolic process
0.52	GO:0055114	oxidation-reduction process
0.43	GO:1901606	alpha-amino acid catabolic process
0.42	GO:1901361	organic cyclic compound catabolic process
0.42	GO:0019439	aromatic compound catabolic process
0.39	GO:1902221	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process
0.37	GO:0042737	drug catabolic process
0.33	GO:0032392	DNA geometric change
0.33	GO:0006260	DNA replication

0.81	GO:0003868	4-hydroxyphenylpyruvate dioxygenase activity
0.52	GO:0046872	metal ion binding
0.49	GO:0004462	lactoylglutathione lyase activity
0.33	GO:0003678	DNA helicase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0000139	Golgi membrane
0.43	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.81	EC:1.13.11.27	GO:0003868
0.49	KEGG:R02530	GO:0004462

tr|Q6TGZ7|Q6TGZ7_DANRE
HN1 protein
Search

0.97	Hematological and neurological expressed 1 protein isoform 1

0.40	GO:0009264	deoxyribonucleotide catabolic process
0.38	GO:0016311	dephosphorylation

0.40

GO:0008253

5'-nucleotidase activity

0.74	GO:0031965	nuclear membrane
0.68	GO:0005730	nucleolus
0.40	GO:0005829	cytosol
0.37	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.40

EC:3.1.3.5

GO:0008253

sp|Q6TH01|C10_DANRE
Protein C10
Search

0.97	Gene rich cluster, C10 gene

0.85	GO:0036343	psychomotor behavior
0.85	GO:0021678	third ventricle development
0.85	GO:0021540	corpus callosum morphogenesis
0.84	GO:0014819	regulation of skeletal muscle contraction
0.78	GO:0048593	camera-type eye morphogenesis
0.76	GO:0050890	cognition
0.73	GO:0009791	post-embryonic development

0.75	GO:0016607	nuclear speck
0.48	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q6TH03|Q6TH03_DANRE
Guanine nucleotide-binding protein subunit gamma
Search

GNG5

0.71	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.50	GO:0072513	positive regulation of secondary heart field cardioblast proliferation
0.48	GO:2000179	positive regulation of neural precursor cell proliferation
0.37	GO:0071377	cellular response to glucagon stimulus
0.35	GO:0007368	determination of left/right symmetry
0.32	GO:0005975	carbohydrate metabolic process

0.64	GO:0004871	signal transducer activity
0.49	GO:0030165	PDZ domain binding
0.34	GO:0003924	GTPase activity
0.33	GO:0008061	chitin binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.81	GO:1905360	GTPase complex
0.80	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.65	GO:0098797	plasma membrane protein complex
0.40	GO:0031680	G-protein beta/gamma-subunit complex
0.40	GO:0005739	mitochondrion
0.38	GO:0070062	extracellular exosome
0.35	GO:0036064	ciliary basal body
0.34	GO:0005813	centrosome
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004553

tr|Q6TH05|Q6TH05_DANRE
GABA(A) receptor-associated protein-like 2
Search

GABARAPL2

0.97	Gamma-aminobutyric acid receptor-associated protein 2

0.77	GO:0006914	autophagy
0.54	GO:1901799	negative regulation of proteasomal protein catabolic process
0.50	GO:0006995	cellular response to nitrogen starvation
0.49	GO:0061726	mitochondrion disassembly
0.48	GO:0007033	vacuole organization
0.45	GO:0070925	organelle assembly
0.37	GO:0006891	intra-Golgi vesicle-mediated transport
0.36	GO:0032781	positive regulation of ATPase activity
0.36	GO:0015031	protein transport
0.34	GO:0043241	protein complex disassembly

0.51	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0051117	ATPase binding
0.36	GO:0000149	SNARE binding
0.35	GO:0050811	GABA receptor binding
0.35	GO:0048487	beta-tubulin binding
0.34	GO:0030957	Tat protein binding
0.34	GO:0008017	microtubule binding
0.33	GO:0004252	serine-type endopeptidase activity

0.58	GO:0000421	autophagosome membrane
0.49	GO:0000139	Golgi membrane
0.44	GO:0005829	cytosol
0.37	GO:0031410	cytoplasmic vesicle
0.33	GO:0012506	vesicle membrane
0.33	GO:0005874	microtubule
0.33	GO:0005783	endoplasmic reticulum
0.32	GO:0005739	mitochondrion

0.33

GO:0004252

tr|Q6TH07|Q6TH07_DANRE
Flotillin 1
Search

FLOT1

0.91	Novel flotillin

0.84	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin
0.84	GO:0060355	positive regulation of cell adhesion molecule production
0.83	GO:0032226	positive regulation of synaptic transmission, dopaminergic
0.83	GO:0070528	protein kinase C signaling
0.83	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway
0.82	GO:1903044	protein localization to membrane raft
0.82	GO:1901741	positive regulation of myoblast fusion
0.82	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.81	GO:0071360	cellular response to exogenous dsRNA
0.81	GO:0048643	positive regulation of skeletal muscle tissue development

0.77	GO:0002020	protease binding
0.68	GO:0046982	protein heterodimerization activity
0.52	GO:0035255	ionotropic glutamate receptor binding

0.82	GO:0016600	flotillin complex
0.81	GO:0001931	uropod
0.79	GO:0034451	centriolar satellite
0.77	GO:0044291	cell-cell contact zone
0.76	GO:0042383	sarcolemma
0.76	GO:0005913	cell-cell adherens junction
0.75	GO:0030027	lamellipodium
0.75	GO:0016323	basolateral plasma membrane
0.73	GO:0008180	COP9 signalosome
0.73	GO:0030864	cortical actin cytoskeleton

tr|Q6TH11|Q6TH11_DANRE
F-box only protein 25
Search

FBXO25

0.97	F-box only protein 25

0.49	GO:0016567	protein ubiquitination
0.44	GO:0014877	response to muscle inactivity involved in regulation of muscle adaptation
0.43	GO:0071549	cellular response to dexamethasone stimulus

0.45	GO:0003779	actin binding
0.38	GO:0004842	ubiquitin-protein transferase activity

0.61	GO:0005634	nucleus
0.54	GO:0019005	SCF ubiquitin ligase complex
0.42	GO:0031974	membrane-enclosed lumen
0.42	GO:0030018	Z disc
0.39	GO:0044446	intracellular organelle part
0.39	GO:0005829	cytosol

0.38

GO:0004842

tr|Q6TH14|Q6TH14_DANRE
Enolase 1, (Alpha)
Search

ENO3

0.89	Beta-enolase 3 transcript variant 1

0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0046496	nicotinamide nucleotide metabolic process
0.38	GO:0043403	skeletal muscle tissue regeneration
0.37	GO:0007568	aging
0.35	GO:0042493	response to drug
0.35	GO:0021762	substantia nigra development
0.34	GO:0006887	exocytosis
0.34	GO:0019319	hexose biosynthetic process

0.78	GO:0004634	phosphopyruvate hydratase activity
0.64	GO:0000287	magnesium ion binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0046982	protein heterodimerization activity

0.77	GO:0000015	phosphopyruvate hydratase complex
0.41	GO:0001917	photoreceptor inner segment
0.41	GO:0043204	perikaryon
0.41	GO:0005886	plasma membrane
0.40	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome
0.34	GO:0000145	exocyst
0.30	GO:0016021	integral component of membrane

0.78

EC:4.2.1.11

GO:0004634

sp|Q6TH15|EIF3D_DANRE
Eukaryotic translation initiation factor 3 subunit D
Search

EIF3D

0.73	Eukaryotic translation initiation factor 3 subunit D

0.81	GO:0002191	cap-dependent translational initiation
0.72	GO:0001731	formation of translation preinitiation complex
0.71	GO:0006446	regulation of translational initiation
0.58	GO:0075525	viral translational termination-reinitiation
0.58	GO:1902416	positive regulation of mRNA binding
0.57	GO:0075522	IRES-dependent viral translational initiation
0.56	GO:0001732	formation of cytoplasmic translation initiation complex
0.51	GO:0045727	positive regulation of translation
0.34	GO:0043044	ATP-dependent chromatin remodeling
0.33	GO:0006414	translational elongation

0.81	GO:0098808	mRNA cap binding
0.72	GO:0003743	translation initiation factor activity
0.34	GO:0042393	histone binding
0.34	GO:0003746	translation elongation factor activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0016887	ATPase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.77	GO:0005852	eukaryotic translation initiation factor 3 complex
0.72	GO:0016282	eukaryotic 43S preinitiation complex
0.72	GO:0033290	eukaryotic 48S preinitiation complex
0.35	GO:0016514	SWI/SNF complex
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.33

GO:0016887

tr|Q6TH20|Q6TH20_DANRE
Developmentally regulated GTP binding protein 2
Search

DRG2

0.97	Developmentally regulated GTP-binding protein 2

0.66	GO:0001883	purine nucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.65	GO:0032549	ribonucleoside binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0005654	nucleoplasm
0.55	GO:0005829	cytosol
0.50	GO:0005739	mitochondrion

tr|Q6TH21|Q6TH21_DANRE
DiGeorge syndrome critical region gene 6
Search

DGCR6

0.97	DiGeorge syndrome critical region gene 6

0.51	GO:0032501	multicellular organismal process
0.48	GO:0007155	cell adhesion
0.48	GO:0009653	anatomical structure morphogenesis
0.46	GO:0009593	detection of chemical stimulus
0.44	GO:0007186	G-protein coupled receptor signaling pathway

0.46	GO:0004984	olfactory receptor activity
0.45	GO:0004930	G-protein coupled receptor activity
0.44	GO:0005515	protein binding

0.50	GO:0005578	proteinaceous extracellular matrix
0.49	GO:0005634	nucleus
0.39	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q6TH22|DDI2_DANRE
Protein DDI1 homolog 2
Search

DDI2

0.94	DNA-damage inducible protein 2

0.61	GO:0006508	proteolysis
0.51	GO:0051604	protein maturation

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.56	GO:0043130	ubiquitin binding
0.52	GO:0042802	identical protein binding

0.49	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol

tr|Q6TH32|Q6TH32_DANRE
Cofilin 1
Search

CFL2

0.93	Cofilin 2 (muscle)

0.84	GO:0030042	actin filament depolymerization
0.56	GO:0030836	positive regulation of actin filament depolymerization
0.54	GO:0046716	muscle cell cellular homeostasis
0.54	GO:0045214	sarcomere organization
0.53	GO:0009888	tissue development
0.53	GO:0060538	skeletal muscle organ development
0.44	GO:0070586	cell-cell adhesion involved in gastrulation
0.42	GO:0001702	gastrulation with mouth forming second
0.42	GO:0044794	positive regulation by host of viral process
0.42	GO:0061371	determination of heart left/right asymmetry

0.74	GO:0003779	actin binding
0.52	GO:0032403	protein complex binding
0.38	GO:0005102	receptor binding
0.34	GO:0035091	phosphatidylinositol binding
0.34	GO:0019903	protein phosphatase binding
0.34	GO:0046872	metal ion binding
0.32	GO:0016787	hydrolase activity

0.74	GO:0015629	actin cytoskeleton
0.53	GO:0030018	Z disc
0.41	GO:0016363	nuclear matrix
0.40	GO:0030027	lamellipodium
0.40	GO:0030863	cortical cytoskeleton
0.39	GO:0005615	extracellular space
0.39	GO:0005911	cell-cell junction
0.38	GO:0044430	cytoskeletal part
0.38	GO:1903561	extracellular vesicle
0.36	GO:0032587	ruffle membrane

0.32

GO:0016787

tr|Q6TH37|Q6TH37_DANRE
Chromobox homolog 8
Search

CBX8

0.94	Chromobox protein 8

0.44	GO:0002244	hematopoietic progenitor cell differentiation
0.44	GO:0000122	negative regulation of transcription by RNA polymerase II
0.36	GO:0016569	covalent chromatin modification
0.34	GO:0006351	transcription, DNA-templated

0.44	GO:0003727	single-stranded RNA binding
0.40	GO:0019904	protein domain specific binding

0.61	GO:0005634	nucleus
0.45	GO:0000792	heterochromatin
0.42	GO:0030175	filopodium
0.42	GO:0030426	growth cone
0.41	GO:0043025	neuronal cell body
0.41	GO:0030425	dendrite
0.40	GO:0009898	cytoplasmic side of plasma membrane
0.39	GO:0043234	protein complex
0.38	GO:0005829	cytosol
0.34	GO:0031974	membrane-enclosed lumen

tr|Q6TH39|Q6TH39_DANRE
Chromosome 2 open reading frame 6
Search

0.80	Deoxycytidine kinase

0.59	GO:0035329	hippo signaling
0.56	GO:0031952	regulation of protein autophosphorylation
0.51	GO:0042327	positive regulation of phosphorylation
0.51	GO:0016310	phosphorylation
0.41	GO:0001756	somitogenesis
0.40	GO:0008283	cell proliferation
0.40	GO:0007417	central nervous system development

0.54	GO:0019209	kinase activator activity
0.53	GO:0016301	kinase activity
0.51	GO:0019900	kinase binding
0.35	GO:0046872	metal ion binding

0.52	GO:0005730	nucleolus
0.50	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome

sp|Q6TH47|STBPA_DANRE
STAM-binding protein-like A
Search

STAMBP

0.94	STAM binding protein a

0.71	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling
0.66	GO:0046580	negative regulation of Ras protein signal transduction
0.64	GO:0000281	mitotic cytokinesis
0.62	GO:0016579	protein deubiquitination
0.59	GO:0043524	negative regulation of neuron apoptotic process
0.40	GO:0035335	peptidyl-tyrosine dephosphorylation
0.39	GO:0006915	apoptotic process
0.38	GO:0006955	immune response
0.38	GO:0007259	JAK-STAT cascade
0.37	GO:0008284	positive regulation of cell proliferation

0.63	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.61	GO:0019904	protein domain specific binding
0.45	GO:0008237	metallopeptidase activity
0.40	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.40	GO:0004725	protein tyrosine phosphatase activity
0.39	GO:0046872	metal ion binding
0.38	GO:0061578	Lys63-specific deubiquitinase activity
0.37	GO:0004888	transmembrane signaling receptor activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding

0.68	GO:0032154	cleavage furrow
0.57	GO:0005654	nucleoplasm
0.57	GO:0005829	cytosol
0.47	GO:0005886	plasma membrane
0.41	GO:0005768	endosome
0.40	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.40

GO:0008138

sp|Q6TLE4|MMGT1_DANRE
Membrane magnesium transporter 1
Search

MMGT1

0.97	LOW QUALITY PROTEIN: membrane magnesium transporter 1

0.44	GO:1903830	magnesium ion transmembrane transport
0.39	GO:0006824	cobalt ion transport
0.39	GO:0006825	copper ion transport
0.37	GO:1903874	ferrous iron transmembrane transport
0.37	GO:0071421	manganese ion transmembrane transport
0.37	GO:0035444	nickel cation transmembrane transport
0.33	GO:0072383	plus-end-directed vesicle transport along microtubule
0.33	GO:0044837	actomyosin contractile ring organization
0.33	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis
0.32	GO:0009058	biosynthetic process

0.44	GO:0015095	magnesium ion transmembrane transporter activity
0.40	GO:0015087	cobalt ion transmembrane transporter activity
0.37	GO:0015093	ferrous iron transmembrane transporter activity
0.37	GO:0005384	manganese ion transmembrane transporter activity
0.37	GO:0005375	copper ion transmembrane transporter activity
0.37	GO:0015099	nickel cation transmembrane transporter activity
0.33	GO:0016740	transferase activity
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.32	GO:0032559	adenyl ribonucleotide binding

0.57	GO:0072546	ER membrane protein complex
0.50	GO:0005769	early endosome
0.47	GO:0005794	Golgi apparatus
0.42	GO:0010008	endosome membrane
0.40	GO:0005886	plasma membrane

0.33

GO:0016740

sp|Q6TLE6|CRCM1_DANRE
Calcium release-activated calcium channel protein 1
Search

ORAI1

0.93	LOW QUALITY PROTEIN: calcium release-activated calcium channel protein 1

0.60	GO:0002115	store-operated calcium entry
0.53	GO:0070509	calcium ion import
0.51	GO:0061180	mammary gland epithelium development
0.47	GO:0070588	calcium ion transmembrane transport
0.41	GO:0051928	positive regulation of calcium ion transport
0.41	GO:0002250	adaptive immune response
0.35	GO:0045214	sarcomere organization

0.52	GO:0015279	store-operated calcium channel activity
0.37	GO:0005516	calmodulin binding
0.36	GO:0042802	identical protein binding

0.52	GO:0016323	basolateral plasma membrane
0.45	GO:0005829	cytosol
0.42	GO:0043234	protein complex
0.37	GO:0005887	integral component of plasma membrane
0.36	GO:0005776	autophagosome
0.35	GO:0031410	cytoplasmic vesicle
0.35	GO:0030426	growth cone

tr|Q6TLF1|Q6TLF1_DANRE
WD repeat and FYVE domain containing 2
Search

WDFY2

0.96	WD repeat and FYVE domain-containing protein 2

0.55	GO:0045600	positive regulation of fat cell differentiation
0.51	GO:0001934	positive regulation of protein phosphorylation
0.49	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway
0.49	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway

0.53	GO:0046872	metal ion binding
0.46	GO:0005545	1-phosphatidylinositol binding
0.35	GO:0005515	protein binding

0.57	GO:0005769	early endosome
0.42	GO:0005829	cytosol
0.40	GO:0005634	nucleus

sp|Q6TLF6|RGN_DANRE
Regucalcin
Search

RGN

0.84	Epididymis secretory protein Li 41

0.68	GO:0050790	regulation of catalytic activity
0.60	GO:0019853	L-ascorbic acid biosynthetic process
0.44	GO:0050848	regulation of calcium-mediated signaling
0.43	GO:0006874	cellular calcium ion homeostasis
0.41	GO:0044093	positive regulation of molecular function
0.40	GO:1903625	negative regulation of DNA catabolic process
0.40	GO:1901318	negative regulation of flagellated sperm motility
0.40	GO:1903011	negative regulation of bone development
0.40	GO:0045019	negative regulation of nitric oxide biosynthetic process
0.39	GO:0010867	positive regulation of triglyceride biosynthetic process

0.70	GO:0030234	enzyme regulator activity
0.69	GO:0005509	calcium ion binding
0.60	GO:0004341	gluconolactonase activity
0.46	GO:0008270	zinc ion binding
0.36	GO:0008081	phosphoric diester hydrolase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.45	GO:0005634	nucleus
0.42	GO:0005576	extracellular region
0.39	GO:0005737	cytoplasm

0.60

EC:3.1.1.17

GO:0004341

tr|Q6TLG1|Q6TLG1_DANRE
Novel protein containing a membrane-associating domain (Wu:fc22a07)
Search

0.80	Synaptophysin

0.34

GO:0048168

regulation of neuronal synaptic plasticity

0.82	GO:0008021	synaptic vesicle
0.40	GO:0099501	exocytic vesicle membrane
0.39	GO:0031301	integral component of organelle membrane
0.36	GO:0030141	secretory granule
0.34	GO:0042470	melanosome

tr|Q6TLG8|Q6TLG8_DANRE
Ribosomal protein S3
Search

RPS3

0.60	Ribosomal protein S3

0.59	GO:0006518	peptide metabolic process
0.58	GO:0043604	amide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.53	GO:0061481	response to TNF agonist
0.53	GO:1901566	organonitrogen compound biosynthetic process
0.53	GO:0010467	gene expression
0.52	GO:1905051	regulation of base-excision repair
0.52	GO:1902546	positive regulation of DNA N-glycosylase activity
0.52	GO:2001272	positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
0.51	GO:0009059	macromolecule biosynthetic process

0.62	GO:0003735	structural constituent of ribosome
0.58	GO:0003723	RNA binding
0.53	GO:0032358	oxidized pyrimidine DNA binding
0.51	GO:0032357	oxidized purine DNA binding
0.51	GO:0097100	supercoiled DNA binding
0.50	GO:0051879	Hsp90 protein binding
0.50	GO:0030544	Hsp70 protein binding
0.49	GO:0044390	ubiquitin-like protein conjugating enzyme binding
0.49	GO:0051018	protein kinase A binding
0.49	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity

0.68	GO:0015935	small ribosomal subunit
0.51	GO:0071159	NF-kappaB complex
0.49	GO:0032587	ruffle membrane
0.48	GO:0005844	polysome
0.48	GO:0005819	spindle
0.48	GO:0022626	cytosolic ribosome
0.47	GO:0005730	nucleolus
0.46	GO:0005759	mitochondrial matrix
0.44	GO:0005783	endoplasmic reticulum
0.42	GO:0031966	mitochondrial membrane

0.49

EC:4.2.99.18

GO:0003906

sp|Q6TLH3|CUED2_DANRE
CUE domain-containing protein 2
Search

CUEDC2

0.97	CUE domain-containing protein 2-A

0.79	GO:0010936	negative regulation of macrophage cytokine production
0.78	GO:1900016	negative regulation of cytokine production involved in inflammatory response

0.69	GO:0031965	nuclear membrane
0.62	GO:0005654	nucleoplasm
0.60	GO:0005829	cytosol

tr|Q6TLH8|Q6TLH8_DANRE
Putative uncharacterized protein
Search

0.66	GO:0065009	regulation of molecular function
0.59	GO:0061564	axon development
0.57	GO:0034063	stress granule assembly
0.57	GO:2000785	regulation of autophagosome assembly
0.56	GO:1990138	neuron projection extension
0.56	GO:0016239	positive regulation of macroautophagy
0.55	GO:1903432	regulation of TORC1 signaling
0.54	GO:0006914	autophagy
0.53	GO:0048667	cell morphogenesis involved in neuron differentiation
0.53	GO:0110053	regulation of actin filament organization

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.54	GO:0017137	Rab GTPase binding

0.58	GO:0044295	axonal growth cone
0.58	GO:0005776	autophagosome
0.57	GO:0032045	guanyl-nucleotide exchange factor complex
0.56	GO:0044304	main axon
0.56	GO:1990316	Atg1/ULK1 kinase complex
0.54	GO:0000932	P-body
0.54	GO:0010494	cytoplasmic stress granule
0.53	GO:0005768	endosome
0.53	GO:0005764	lysosome
0.50	GO:0005615	extracellular space

tr|Q6TLH9|Q6TLH9_DANRE
Z2610510D14Rik
Search

ZMAT2

0.93	Zinc finger matrin-type protein 2

0.45	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0006427	histidyl-tRNA aminoacylation

0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.36	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.36	GO:0140101	catalytic activity, acting on a tRNA
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:6.1

GO:0016875

sp|Q6TNP8|VP26A_DANRE
Vacuolar protein sorting-associated protein 26A
Search

VPS26A

0.94	Vacuolar protein sorting-associated protein 26A

0.61	GO:0007165	signal transduction
0.54	GO:1990126	retrograde transport, endosome to plasma membrane
0.53	GO:0042147	retrograde transport, endosome to Golgi
0.43	GO:0006886	intracellular protein transport
0.34	GO:0016241	regulation of macroautophagy
0.34	GO:0198738	cell-cell signaling by wnt
0.33	GO:0071346	cellular response to interferon-gamma

0.43	GO:0008565	protein transporter activity
0.34	GO:0005515	protein binding
0.34	GO:0004386	helicase activity

0.55	GO:0097422	tubular endosome
0.54	GO:0030904	retromer complex
0.52	GO:0005769	early endosome
0.51	GO:0010008	endosome membrane
0.50	GO:0005764	lysosome
0.48	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.33	GO:0045335	phagocytic vesicle
0.33	GO:0005770	late endosome
0.30	GO:0031224	intrinsic component of membrane

tr|Q6TNP9|Q6TNP9_DANRE
Tubulin alpha chain
Search

0.53	Tubulin alpha chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.42	GO:0007094	mitotic spindle assembly checkpoint

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0005874	microtubule
0.46	GO:0005737	cytoplasm

tr|Q6TNR0|Q6TNR0_DANRE
Ribonuclease
Search

RNASEH2A

0.55	Ribonuclease

0.70	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.52	GO:0006298	mismatch repair
0.51	GO:0006401	RNA catabolic process
0.49	GO:0033567	DNA replication, Okazaki fragment processing
0.36	GO:0045005	DNA-dependent DNA replication maintenance of fidelity
0.35	GO:0007010	cytoskeleton organization
0.34	GO:0006468	protein phosphorylation
0.34	GO:0035556	intracellular signal transduction

0.74	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.59	GO:0003723	RNA binding
0.35	GO:0046872	metal ion binding
0.35	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.57	GO:0032299	ribonuclease H2 complex
0.47	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol

0.74

EC:3.1.26.4

GO:0004523

sp|Q6TNR1|RHPN2_DANRE
Rhophilin-2
Search

RHPN2

0.61	Rhophilin Rho GTPase binding protein 2

0.59

GO:0007165

signal transduction

0.40	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005829	cytosol

tr|Q6TNS1|Q6TNS1_DANRE
Par-6 family cell polarity regulator gamma b
Search

PARD6B

0.96	Partitioning defective 6 like protein beta

0.80	GO:0007163	establishment or maintenance of cell polarity
0.71	GO:0007043	cell-cell junction assembly
0.47	GO:0048696	regulation of collateral sprouting in absence of injury
0.47	GO:0035844	cloaca development
0.46	GO:0045176	apical protein localization
0.46	GO:0048793	pronephros development
0.45	GO:0006461	protein complex assembly
0.45	GO:0021510	spinal cord development
0.45	GO:0001841	neural tube formation
0.45	GO:0035050	embryonic heart tube development

0.34

GO:0005515

protein binding

0.55	GO:0016324	apical plasma membrane
0.50	GO:0005923	bicellular tight junction
0.48	GO:0005938	cell cortex
0.46	GO:0032154	cleavage furrow
0.45	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.34	GO:0043234	protein complex

sp|Q6TNS2|PK1IP_DANRE
p21-activated protein kinase-interacting protein 1-like
Search

PAK1IP1

0.85	WD repeat-containing protein 41

0.59	GO:1901796	regulation of signal transduction by p53 class mediator
0.55	GO:0060021	palate development
0.55	GO:0042273	ribosomal large subunit biogenesis
0.53	GO:0008283	cell proliferation
0.52	GO:0016310	phosphorylation
0.40	GO:0009968	negative regulation of signal transduction
0.34	GO:0006364	rRNA processing

0.54	GO:0016301	kinase activity
0.34	GO:0005515	protein binding

0.51	GO:0005730	nucleolus
0.30	GO:0044425	membrane part

sp|Q6TNS7|RABL3_DANRE
Rab-like protein 3
Search

RABL3

0.46	Homogentisate 1,2-dioxygenase

0.44	GO:1902222	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process
0.43	GO:0006570	tyrosine metabolic process
0.43	GO:0006558	L-phenylalanine metabolic process
0.43	GO:0009074	aromatic amino acid family catabolic process
0.41	GO:0042737	drug catabolic process
0.36	GO:0055114	oxidation-reduction process

0.64	GO:0001883	purine nucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.64	GO:0032549	ribonucleoside binding
0.60	GO:0003924	GTPase activity
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0004411	homogentisate 1,2-dioxygenase activity
0.39	GO:0042802	identical protein binding

0.44	EC:1.13.11.5	GO:0004411
0.44	KEGG:R02519	GO:0004411

sp|Q6TNT2|ANR46_DANRE
Ankyrin repeat domain-containing protein 46
Search

ANKRD46

0.97	Ankyrin repeat domain-containing protein 46

0.35	GO:0006886	intracellular protein transport
0.31	GO:0006629	lipid metabolic process

0.36	GO:0035091	phosphatidylinositol binding
0.32	GO:0043531	ADP binding

0.32	GO:0005622	intracellular
0.30	GO:0016020	membrane

tr|Q6TNT8|Q6TNT8_DANRE
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
Search

GNAI2

0.85	Guanine nucleotide binding protein alpha inhibiting 2

0.82	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.52	GO:0007212	dopamine receptor signaling pathway
0.52	GO:0016239	positive regulation of macroautophagy
0.48	GO:0046039	GTP metabolic process
0.48	GO:0051301	cell division
0.44	GO:0001973	adenosine receptor signaling pathway
0.44	GO:0007214	gamma-aminobutyric acid signaling pathway
0.43	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.42	GO:0008283	cell proliferation
0.38	GO:0007049	cell cycle

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.64	GO:0004871	signal transducer activity
0.52	GO:0019003	GDP binding
0.49	GO:0001664	G-protein coupled receptor binding
0.38	GO:0032794	GTPase activating protein binding
0.36	GO:0019904	protein domain specific binding
0.36	GO:0046872	metal ion binding

0.56	GO:0030496	midbody
0.54	GO:0005813	centrosome
0.49	GO:1905360	GTPase complex
0.49	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.48	GO:0031981	nuclear lumen
0.47	GO:0000139	Golgi membrane
0.47	GO:0005789	endoplasmic reticulum membrane
0.44	GO:0098797	plasma membrane protein complex
0.42	GO:0030425	dendrite
0.42	GO:0044297	cell body

tr|Q6TNT9|Q6TNT9_DANRE
Rab GDP dissociation inhibitor
Search

GDI2

0.68	Rab GDP dissociation inhibitor beta

0.76	GO:0007264	small GTPase mediated signal transduction
0.75	GO:0043547	positive regulation of GTPase activity
0.65	GO:0015031	protein transport
0.48	GO:0090315	negative regulation of protein targeting to membrane
0.40	GO:0050771	negative regulation of axonogenesis
0.38	GO:0045773	positive regulation of axon extension
0.37	GO:0051592	response to calcium ion
0.36	GO:0016192	vesicle-mediated transport
0.35	GO:0051056	regulation of small GTPase mediated signal transduction
0.35	GO:0002283	neutrophil activation involved in immune response

0.85	GO:0005093	Rab GDP-dissociation inhibitor activity
0.76	GO:0005096	GTPase activator activity
0.39	GO:0031267	small GTPase binding
0.33	GO:0003723	RNA binding

0.51	GO:0043209	myelin sheath
0.49	GO:0005737	cytoplasm
0.44	GO:0030496	midbody
0.43	GO:0012505	endomembrane system
0.39	GO:0043227	membrane-bounded organelle
0.38	GO:0043229	intracellular organelle
0.37	GO:0043230	extracellular organelle
0.37	GO:0043025	neuronal cell body
0.37	GO:0030424	axon
0.36	GO:0005615	extracellular space

sp|Q6TNU3|INT10_DANRE
Integrator complex subunit 10
Search

INTS10

0.95	Integrator complex subunit 10

0.83	GO:0016180	snRNA processing
0.35	GO:0042795	snRNA transcription by RNA polymerase II

0.33

GO:0005515

protein binding

0.84	GO:0032039	integrator complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q6TNU4|FEN1A_DANRE
Flap endonuclease 1
Search

FEN1

0.64	Flap endonuclease 1-B

0.81	GO:0043137	DNA replication, removal of RNA primer
0.69	GO:0006284	base-excision repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.56	GO:0045876	positive regulation of sister chromatid cohesion
0.38	GO:0007613	memory
0.36	GO:0030262	apoptotic nuclear changes
0.35	GO:0032201	telomere maintenance via semi-conservative replication
0.35	GO:0006308	DNA catabolic process
0.35	GO:0060041	retina development in camera-type eye
0.35	GO:0009650	UV protection

0.79	GO:0048256	flap endonuclease activity
0.74	GO:0008409	5'-3' exonuclease activity
0.72	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters
0.61	GO:0000287	magnesium ion binding
0.55	GO:0003677	DNA binding
0.49	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.35	GO:0030145	manganese ion binding
0.35	GO:0008309	double-stranded DNA exodeoxyribonuclease activity
0.33	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity

0.71	GO:0005730	nucleolus
0.68	GO:0005654	nucleoplasm
0.60	GO:0005739	mitochondrion
0.52	GO:0000784	nuclear chromosome, telomeric region
0.43	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.72

EC:3.1.21

GO:0016888

tr|Q6TNU6|Q6TNU6_DANRE
Dihydrolipoyl dehydrogenase
Search

0.47	Dihydrolipoyl dehydrogenase

0.68	GO:0045454	cell redox homeostasis
0.59	GO:0022900	electron transport chain
0.58	GO:0018335	protein succinylation
0.54	GO:0048240	sperm capacitation
0.51	GO:0007369	gastrulation
0.51	GO:0006086	acetyl-CoA biosynthetic process from pyruvate
0.49	GO:0042391	regulation of membrane potential
0.44	GO:0060047	heart contraction
0.44	GO:0006119	oxidative phosphorylation
0.43	GO:0045333	cellular respiration

0.77	GO:0004148	dihydrolipoyl dehydrogenase activity
0.65	GO:0050660	flavin adenine dinucleotide binding
0.61	GO:0009055	electron transfer activity
0.55	GO:0034604	pyruvate dehydrogenase (NAD+) activity
0.41	GO:0043544	lipoamide binding
0.36	GO:0051287	NAD binding
0.33	GO:0005515	protein binding

0.55	GO:0043159	acrosomal matrix
0.52	GO:0045252	oxoglutarate dehydrogenase complex
0.51	GO:0043209	myelin sheath
0.51	GO:0045254	pyruvate dehydrogenase complex
0.50	GO:0005929	cilium
0.47	GO:0031974	membrane-enclosed lumen
0.45	GO:0044428	nuclear part
0.44	GO:0005739	mitochondrion

0.77	EC:1.8.1.4	GO:0004148
0.55	KEGG:R00209	GO:0034604

tr|Q6TNV0|Q6TNV0_DANRE
Cytochrome c oxidase subunit IV isoform 1
Search

COX4I1

0.56	Mitochondrial cytochrome c oxidase subunit IV

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.46	GO:0001666	response to hypoxia
0.39	GO:0006119	oxidative phosphorylation
0.39	GO:0009060	aerobic respiration
0.34	GO:0007584	response to nutrient
0.34	GO:0050829	defense response to Gram-negative bacterium
0.34	GO:0036294	cellular response to decreased oxygen levels
0.33	GO:0006955	immune response
0.33	GO:0007017	microtubule-based process

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity
0.34	GO:0001530	lipopolysaccharide binding
0.34	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0003924	GTPase activity
0.33	GO:0005515	protein binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding

0.49	GO:0005751	mitochondrial respiratory chain complex IV
0.40	GO:0005634	nucleus
0.34	GO:0070062	extracellular exosome
0.33	GO:0005874	microtubule
0.30	GO:0016021	integral component of membrane

0.65

GO:0016676

tr|Q6TNW3|Q6TNW3_DANRE
ATP-binding cassette, sub-family E (OABP), member 1
Search

ABCE1

0.94	ATP-binding cassette sub-family E member 1

0.54	GO:0060702	negative regulation of endoribonuclease activity
0.46	GO:0000054	ribosomal subunit export from nucleus
0.43	GO:0006415	translational termination
0.43	GO:0006413	translational initiation
0.34	GO:0015716	organic phosphonate transport
0.34	GO:0060338	regulation of type I interferon-mediated signaling pathway
0.34	GO:0015748	organophosphate ester transport
0.34	GO:0099133	ATP hydrolysis coupled anion transmembrane transport
0.33	GO:0016032	viral process

0.58	GO:0016887	ATPase activity
0.54	GO:0060698	endoribonuclease inhibitor activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0043024	ribosomal small subunit binding
0.40	GO:0005506	iron ion binding
0.34	GO:0015604	organic phosphonate transmembrane transporter activity
0.34	GO:0015605	organophosphate ester transmembrane transporter activity
0.33	GO:0051539	4 iron, 4 sulfur cluster binding

0.47	GO:0005829	cytosol
0.44	GO:0005852	eukaryotic translation initiation factor 3 complex
0.43	GO:0005739	mitochondrion
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.58

GO:0016887

sp|Q6TV19|DICER_DANRE
Endoribonuclease Dicer
Search

DICER1

0.93	LOW QUALITY PROTEIN: endoribonuclease Dicer

0.76	GO:0031047	gene silencing by RNA
0.68	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.64	GO:0036404	conversion of ds siRNA to ss siRNA
0.60	GO:0016441	posttranscriptional gene silencing
0.56	GO:0017148	negative regulation of translation
0.54	GO:0022618	ribonucleoprotein complex assembly
0.51	GO:0006309	apoptotic DNA fragmentation
0.49	GO:0034470	ncRNA processing
0.41	GO:0014040	positive regulation of Schwann cell differentiation
0.41	GO:0032290	peripheral nervous system myelin formation

0.75	GO:0004525	ribonuclease III activity
0.61	GO:0035197	siRNA binding
0.58	GO:0070883	pre-miRNA binding
0.54	GO:0019904	protein domain specific binding
0.54	GO:0003725	double-stranded RNA binding
0.52	GO:0030554	adenyl nucleotide binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0008144	drug binding
0.51	GO:0004530	deoxyribonuclease I activity

0.63	GO:0070578	RISC-loading complex
0.62	GO:0035068	micro-ribonucleoprotein complex
0.57	GO:0070062	extracellular exosome
0.50	GO:0016442	RISC complex
0.41	GO:0005634	nucleus
0.39	GO:0030426	growth cone
0.39	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.38	GO:0030425	dendrite
0.38	GO:0030424	axon
0.38	GO:0034507	chromosome, centromeric outer repeat region

0.75

EC:3.1.26.3

GO:0004525

tr|Q6U1J7|Q6U1J7_DANRE
Brain-type fatty acid-binding protein b
Search

FABP7

0.81	Brain-type fatty acid-binding protein b

0.52	GO:0060134	prepulse inhibition
0.51	GO:0021846	cell proliferation in forebrain
0.47	GO:0022008	neurogenesis
0.39	GO:0061024	membrane organization
0.39	GO:2001245	regulation of phosphatidylcholine biosynthetic process
0.38	GO:0055091	phospholipid homeostasis
0.38	GO:0044539	long-chain fatty acid import
0.38	GO:0046320	regulation of fatty acid oxidation
0.38	GO:0042632	cholesterol homeostasis
0.37	GO:0050673	epithelial cell proliferation

0.72	GO:0008289	lipid binding
0.42	GO:0033293	monocarboxylic acid binding
0.40	GO:0043178	alcohol binding
0.36	GO:0008092	cytoskeletal protein binding
0.34	GO:0008134	transcription factor binding
0.33	GO:0097159	organic cyclic compound binding
0.33	GO:0016787	hydrolase activity

0.49	GO:0043025	neuronal cell body
0.47	GO:0005911	cell-cell junction
0.44	GO:0042995	cell projection
0.43	GO:0043209	myelin sheath
0.39	GO:0071944	cell periphery
0.36	GO:0005615	extracellular space
0.34	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.34	GO:0005759	mitochondrial matrix
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016787

sp|Q6UFS5|ZN503_DANRE
Zinc finger protein 503
Search

ZNF503

0.86	Zinc finger protein 503

0.44	GO:0048596	embryonic camera-type eye morphogenesis
0.43	GO:0030902	hindbrain development
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.51	GO:0003676	nucleic acid binding
0.32	GO:0046872	metal ion binding

0.38

GO:0005634

nucleus

tr|Q6V7J8|Q6V7J8_DANRE
Arylalkylamine N-acetyltransferase
Search

0.82	Retinal arylalkylamine N-acetyltransferase

0.54	GO:0030187	melatonin biosynthetic process
0.52	GO:0007623	circadian rhythm
0.48	GO:0071320	cellular response to cAMP
0.46	GO:0006474	N-terminal protein amino acid acetylation
0.45	GO:0009416	response to light stimulus
0.42	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep
0.38	GO:0051412	response to corticosterone
0.37	GO:0034695	response to prostaglandin E
0.37	GO:0010043	response to zinc ion
0.37	GO:0051592	response to calcium ion

0.68	GO:0008080	N-acetyltransferase activity
0.37	GO:0071889	14-3-3 protein binding

0.46	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0005829	cytosol

0.68

GO:0008080

tr|Q6V9B5|Q6V9B5_DANRE
Chemokine (C-X-C motif) ligand 12b (Stromal cell-derived factor 1)
Search

0.97	Chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.68	GO:0006952	defense response
0.66	GO:0021730	trigeminal sensory nucleus development
0.65	GO:0097535	lymphoid lineage cell migration into thymus
0.64	GO:0050930	induction of positive chemotaxis
0.63	GO:0031290	retinal ganglion cell axon guidance
0.62	GO:0042074	cell migration involved in gastrulation
0.62	GO:0050918	positive chemotaxis
0.61	GO:0001764	neuron migration

0.84	GO:0008009	chemokine activity
0.63	GO:0042056	chemoattractant activity
0.48	GO:0045236	CXCR chemokine receptor binding

0.66	GO:0005576	extracellular region
0.44	GO:0009897	external side of plasma membrane

tr|Q6V9Y8|Q6V9Y8_DANRE
Glypican 3 (Fragment)
Search

GPC3

0.96	Intestinal protein OCI-5 (Fragment)

0.70	GO:0009966	regulation of signal transduction
0.55	GO:0061209	cell proliferation involved in mesonephros development
0.55	GO:0072180	mesonephric duct morphogenesis
0.55	GO:0072203	cell proliferation involved in metanephros development
0.54	GO:0048598	embryonic morphogenesis
0.54	GO:0010463	mesenchymal cell proliferation
0.53	GO:0030282	bone mineralization
0.53	GO:0030316	osteoclast differentiation
0.53	GO:0046326	positive regulation of glucose import
0.53	GO:0035137	hindlimb morphogenesis

0.77	GO:0043395	heparan sulfate proteoglycan binding
0.57	GO:0060422	peptidyl-dipeptidase inhibitor activity
0.32	GO:0003735	structural constituent of ribosome

0.83	GO:0046658	anchored component of plasma membrane
0.76	GO:0005578	proteinaceous extracellular matrix
0.50	GO:0005764	lysosome
0.39	GO:0005796	Golgi lumen
0.38	GO:0005615	extracellular space
0.36	GO:0005775	vacuolar lumen
0.36	GO:1903561	extracellular vesicle
0.36	GO:0005887	integral component of plasma membrane
0.34	GO:0005788	endoplasmic reticulum lumen
0.32	GO:0005840	ribosome

sp|Q6VEU3|PNO1_DANRE
RNA-binding protein PNO1
Search

PNO1

0.96	Partner of NOB1 homolog

0.59

GO:0003723

RNA binding

0.61

GO:0005730

nucleolus

sp|Q6VN46|MYG_DANRE
Myoglobin
Search

0.86

Myoglobin

0.79	GO:0015671	oxygen transport
0.45	GO:0014823	response to activity
0.44	GO:0001570	vasculogenesis
0.44	GO:0048565	digestive tract development
0.44	GO:0001666	response to hypoxia

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.54	GO:0046872	metal ion binding

sp|Q6VNZ9|MYF6_DANRE
Myogenic factor 6
Search

MYF6

0.86	Myogenic regulatory factor 4

0.81	GO:0007517	muscle organ development
0.59	GO:0014706	striated muscle tissue development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0001756	somitogenesis
0.52	GO:0006366	transcription by RNA polymerase II
0.51	GO:0048729	tissue morphogenesis
0.51	GO:0048743	positive regulation of skeletal muscle fiber development
0.51	GO:0051254	positive regulation of RNA metabolic process

0.68	GO:0046983	protein dimerization activity
0.55	GO:0003677	DNA binding
0.54	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.48	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0003682	chromatin binding
0.33	GO:0004725	protein tyrosine phosphatase activity

0.61	GO:0005634	nucleus
0.36	GO:0005667	transcription factor complex
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0032993	protein-DNA complex
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.1.3.48

GO:0004725

tr|Q6VUB8|Q6VUB8_DANRE
Zic family member 5 (Odd-paired homolog, Drosophila)
Search

ZIC5

0.88	Zinc finger protein Ap-Zic

0.57	GO:0061351	neural precursor cell proliferation
0.55	GO:0007420	brain development
0.53	GO:0001841	neural tube formation
0.52	GO:0060070	canonical Wnt signaling pathway
0.50	GO:0050767	regulation of neurogenesis
0.49	GO:0042127	regulation of cell proliferation
0.40	GO:0060059	embryonic retina morphogenesis in camera-type eye
0.40	GO:0014029	neural crest formation
0.38	GO:0042307	positive regulation of protein import into nucleus
0.37	GO:0045893	positive regulation of transcription, DNA-templated

0.50	GO:0003676	nucleic acid binding
0.36	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0046872	metal ion binding

0.38	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm

tr|Q6W4T8|Q6W4T8_DANRE
Hairy-related 11
Search

0.10	transcription factor HES-4-B-like

0.64	GO:0000122	negative regulation of transcription by RNA polymerase II
0.63	GO:0007219	Notch signaling pathway
0.55	GO:0009952	anterior/posterior pattern specification
0.54	GO:0006351	transcription, DNA-templated
0.54	GO:0043009	chordate embryonic development
0.53	GO:0060429	epithelium development
0.52	GO:0048511	rhythmic process
0.51	GO:0048731	system development
0.51	GO:2000026	regulation of multicellular organismal development
0.49	GO:0035282	segmentation

0.68	GO:0046983	protein dimerization activity
0.54	GO:0003677	DNA binding
0.50	GO:0001067	regulatory region nucleic acid binding
0.49	GO:0043426	MRF binding
0.47	GO:0001102	RNA polymerase II activating transcription factor binding
0.46	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.46	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.46	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.46	GO:0003714	transcription corepressor activity
0.45	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.41	GO:0043233	organelle lumen
0.38	GO:0044446	intracellular organelle part
0.36	GO:0005667	transcription factor complex
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.35

EC:1.13.11

GO:0016702

tr|Q6W6P1|Q6W6P1_DANRE
Cellular retinol-binding protein type 1
Search

0.95	Cellular retinol-binding protein type 1

0.72	GO:0006776	vitamin A metabolic process
0.71	GO:0002138	retinoic acid biosynthetic process
0.51	GO:0033189	response to vitamin A
0.50	GO:0030852	regulation of granulocyte differentiation
0.49	GO:0042572	retinol metabolic process
0.38	GO:0055088	lipid homeostasis
0.34	GO:0006958	complement activation, classical pathway
0.33	GO:0006796	phosphate-containing compound metabolic process
0.33	GO:0006508	proteolysis
0.32	GO:0072525	pyridine-containing compound biosynthetic process

0.72	GO:0008289	lipid binding
0.50	GO:0019842	vitamin binding
0.40	GO:0043178	alcohol binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0005829	cytosol
0.48	GO:0005811	lipid droplet
0.44	GO:0005654	nucleoplasm
0.38	GO:0044297	cell body

0.33

GO:0004252

sp|Q6W990|HXADA_DANRE
Homeobox protein Hox-A13a
Search

HOXA13

0.97	LOW QUALITY PROTEIN: homeobox protein Hox-A13

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.44	GO:1902679	negative regulation of RNA biosynthetic process
0.39	GO:0007275	multicellular organism development
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:2001055	positive regulation of mesenchymal cell apoptotic process
0.35	GO:0060847	endothelial cell fate specification
0.35	GO:0001886	endothelial cell morphogenesis
0.35	GO:0033574	response to testosterone

0.62	GO:0043565	sequence-specific DNA binding
0.45	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0035326	enhancer binding
0.34	GO:0001012	RNA polymerase II regulatory region DNA binding
0.33	GO:0003690	double-stranded DNA binding

0.60

GO:0005634

nucleus

tr|Q6W9E1|Q6W9E1_DANRE
BHLH transcription factor FIG alpha
Search

FIGLA

0.84	Factor in the germline alpha

0.42

GO:0008585

female gonad development

0.68

GO:0046983

protein dimerization activity

tr|Q6WFZ4|Q6WFZ4_DANRE
Metaxin 2
Search

MTX2

0.90

Metaxin 2

0.78	GO:0006626	protein targeting to mitochondrion
0.34	GO:0032781	positive regulation of ATPase activity
0.34	GO:0097428	protein maturation by iron-sulfur cluster transfer
0.34	GO:0051259	protein oligomerization

0.35	GO:0001671	ATPase activator activity
0.34	GO:0051087	chaperone binding
0.32	GO:0003723	RNA binding

0.77	GO:0005741	mitochondrial outer membrane
0.49	GO:0005730	nucleolus
0.30	GO:0016021	integral component of membrane

tr|Q6WQ24|Q6WQ24_DANRE
Parathyroid hormone 1b
Search

0.81	Parathyroid hormone ligand type-1

0.77	GO:0046326	positive regulation of glucose import
0.76	GO:0055074	calcium ion homeostasis
0.76	GO:0010469	regulation of receptor activity
0.75	GO:0072503	cellular divalent inorganic cation homeostasis
0.70	GO:0006875	cellular metal ion homeostasis
0.50	GO:0090290	positive regulation of osteoclast proliferation
0.50	GO:0071866	negative regulation of apoptotic process in bone marrow
0.49	GO:0071864	positive regulation of cell proliferation in bone marrow
0.49	GO:0060732	positive regulation of inositol phosphate biosynthetic process
0.49	GO:0045725	positive regulation of glycogen biosynthetic process

0.79	GO:0005179	hormone activity
0.60	GO:0031856	parathyroid hormone receptor binding
0.49	GO:0051428	peptide hormone receptor binding
0.47	GO:0047485	protein N-terminus binding
0.47	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

0.66	GO:0005576	extracellular region
0.35	GO:0005622	intracellular

tr|Q6XFR2|Q6XFR2_DANRE
Glycophorin C
Search

GYPC

0.97	Glycophorin C (Gerbich blood group)

0.66	GO:0071205	protein localization to juxtaparanode region of axon
0.43	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.42	GO:0008037	cell recognition
0.41	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.39	GO:0042297	vocal learning
0.39	GO:0071625	vocalization behavior
0.39	GO:0071109	superior temporal gyrus development
0.38	GO:0035176	social behavior
0.38	GO:0021761	limbic system development
0.38	GO:0021794	thalamus development

0.41	GO:0050839	cell adhesion molecule binding
0.40	GO:0042803	protein homodimerization activity
0.40	GO:0005102	receptor binding
0.38	GO:0004872	receptor activity
0.36	GO:0019899	enzyme binding
0.34	GO:0005509	calcium ion binding

0.47	GO:0030863	cortical cytoskeleton
0.42	GO:0005913	cell-cell adherens junction
0.40	GO:0005887	integral component of plasma membrane
0.39	GO:0030673	axolemma
0.37	GO:0005769	early endosome
0.37	GO:0034705	potassium channel complex
0.37	GO:0009986	cell surface
0.37	GO:0019897	extrinsic component of plasma membrane
0.36	GO:0005794	Golgi apparatus
0.36	GO:0033010	paranodal junction

tr|Q6XG62|Q6XG62_DANRE
Protein S100
Search

0.92	Ictacalcin

0.70	GO:0005509	calcium ion binding
0.58	GO:0046914	transition metal ion binding

0.30

GO:0005623

cell

tr|Q6XNL8|Q6XNL8_DANRE
Actin
Search

0.60	Fast skeletal muscle alpha-actin

0.58	GO:0090131	mesenchyme migration
0.51	GO:0030240	skeletal muscle thin filament assembly
0.50	GO:0010628	positive regulation of gene expression
0.48	GO:0048741	skeletal muscle fiber development
0.42	GO:0007507	heart development
0.39	GO:0033275	actin-myosin filament sliding
0.37	GO:0060415	muscle tissue morphogenesis
0.37	GO:0060047	heart contraction
0.37	GO:0043503	skeletal muscle fiber adaptation
0.37	GO:0010226	response to lithium ion

0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0017022	myosin binding
0.37	GO:0017056	structural constituent of nuclear pore
0.35	GO:0031013	troponin I binding
0.35	GO:0031432	titin binding
0.35	GO:0048306	calcium-dependent protein binding
0.35	GO:0005523	tropomyosin binding
0.34	GO:0003785	actin monomer binding

0.55	GO:0030175	filopodium
0.55	GO:0030027	lamellipodium
0.54	GO:0044297	cell body
0.49	GO:0042641	actomyosin
0.48	GO:0005884	actin filament
0.48	GO:0097517	contractile actin filament bundle
0.48	GO:0030017	sarcomere
0.47	GO:0036379	myofilament
0.36	GO:0072562	blood microparticle
0.36	GO:0070062	extracellular exosome

0.34

GO:0016887

tr|Q6XQJ0|Q6XQJ0_DANRE
Renin
Search

REN

0.97

Pro-renin

0.61	GO:0006508	proteolysis
0.53	GO:0002002	regulation of angiotensin levels in blood
0.52	GO:0002018	renin-angiotensin regulation of aldosterone production
0.51	GO:0042756	drinking behavior
0.49	GO:0001823	mesonephros development
0.49	GO:0008584	male gonad development
0.48	GO:0042445	hormone metabolic process
0.48	GO:0048469	cell maturation
0.47	GO:0051604	protein maturation
0.47	GO:0043408	regulation of MAPK cascade

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.45	GO:0005102	receptor binding

0.47	GO:0045177	apical part of cell
0.46	GO:0005615	extracellular space
0.43	GO:0005764	lysosome
0.36	GO:0042470	melanosome
0.30	GO:0016020	membrane

tr|Q6XZH1|Q6XZH1_DANRE
POU domain protein
Search

0.52	POU domain, class 4, transcription factor 3

0.65	GO:0007605	sensory perception of sound
0.63	GO:0048513	animal organ development
0.60	GO:0050885	neuromuscular process controlling balance
0.60	GO:0031290	retinal ganglion cell axon guidance
0.59	GO:0048675	axon extension
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0006355	regulation of transcription, DNA-templated
0.54	GO:0009888	tissue development
0.54	GO:0021562	vestibulocochlear nerve development
0.53	GO:1902870	negative regulation of amacrine cell differentiation

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0003690	double-stranded DNA binding
0.50	GO:1990841	promoter-specific chromatin binding
0.50	GO:0003714	transcription corepressor activity
0.38	GO:0003713	transcription coactivator activity
0.38	GO:0035326	enhancer binding
0.37	GO:0051020	GTPase binding
0.37	GO:0003697	single-stranded DNA binding

0.61	GO:0005634	nucleus
0.50	GO:0070013	intracellular organelle lumen
0.45	GO:0044446	intracellular organelle part
0.40	GO:0005737	cytoplasm
0.37	GO:0043005	neuron projection
0.36	GO:0005694	chromosome
0.34	GO:0005667	transcription factor complex
0.33	GO:0005886	plasma membrane

sp|Q6YBR5|NGF_DANRE
Nerve growth factor
Search

NGF

0.70	Nerve growth factor beta polypeptide

0.76	GO:0010469	regulation of receptor activity
0.44	GO:0048812	neuron projection morphogenesis
0.43	GO:0043524	negative regulation of neuron apoptotic process
0.42	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors
0.42	GO:0045664	regulation of neuron differentiation
0.41	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.41	GO:0010951	negative regulation of endopeptidase activity
0.41	GO:0007267	cell-cell signaling
0.39	GO:0010628	positive regulation of gene expression
0.34	GO:0007422	peripheral nervous system development

0.78	GO:0008083	growth factor activity
0.48	GO:0005163	nerve growth factor receptor binding
0.43	GO:0008191	metalloendopeptidase inhibitor activity
0.34	GO:0090729	toxin activity

0.40	GO:0005576	extracellular region
0.40	GO:0031410	cytoplasmic vesicle
0.30	GO:0031224	intrinsic component of membrane

tr|Q6YBS2|Q6YBS2_DANRE
Adenylyl cyclase-associated protein
Search

CAP1

0.74	Adenylyl cyclase-associated protein 1

0.71	GO:0007010	cytoskeleton organization
0.70	GO:0030029	actin filament-based process
0.55	GO:0001667	ameboidal-type cell migration
0.52	GO:0009653	anatomical structure morphogenesis
0.49	GO:0048869	cellular developmental process
0.49	GO:0045761	regulation of adenylate cyclase activity
0.47	GO:0007163	establishment or maintenance of cell polarity
0.46	GO:0061053	somite development
0.46	GO:0006898	receptor-mediated endocytosis
0.46	GO:0035282	segmentation

0.74	GO:0003779	actin binding
0.50	GO:0008179	adenylate cyclase binding
0.41	GO:0042802	identical protein binding
0.33	GO:0003735	structural constituent of ribosome

0.53	GO:0030864	cortical actin cytoskeleton
0.46	GO:0005615	extracellular space
0.43	GO:0014069	postsynaptic density
0.36	GO:0005925	focal adhesion
0.36	GO:1903561	extracellular vesicle
0.35	GO:0035578	azurophil granule lumen
0.35	GO:0005886	plasma membrane
0.33	GO:0015934	large ribosomal subunit
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|Q6YI49|Q6YI49_DANRE
Ubiquitin carboxyl-terminal hydrolase
Search

UCHL1

0.57	Ubiquitin carboxyl-terminal hydrolase

0.76	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.53	GO:0007412	axon target recognition
0.53	GO:0019896	axonal transport of mitochondrion
0.52	GO:0042755	eating behavior
0.52	GO:0002931	response to ischemia
0.52	GO:0007628	adult walking behavior
0.51	GO:0048747	muscle fiber development
0.51	GO:0043407	negative regulation of MAP kinase activity
0.51	GO:0050905	neuromuscular process

0.79	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.61	GO:0016874	ligase activity
0.54	GO:0031694	alpha-2A adrenergic receptor binding
0.50	GO:0043130	ubiquitin binding
0.49	GO:0031625	ubiquitin protein ligase binding
0.48	GO:0008242	omega peptidase activity
0.47	GO:0004197	cysteine-type endopeptidase activity

0.51	GO:1904115	axon cytoplasm
0.50	GO:0044306	neuron projection terminus
0.50	GO:0043209	myelin sheath
0.49	GO:0043025	neuronal cell body
0.46	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.39	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0070062	extracellular exosome

0.61

GO:0016874

tr|Q6YI96|Q6YI96_DANRE
BarH-class homeodomain transcription factor
Search

BARHL2

0.97	BarH-class homeodomain transcription factor

0.59	GO:0001764	neuron migration
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0006366	transcription by RNA polymerase II
0.56	GO:0010468	regulation of gene expression
0.55	GO:1902680	positive regulation of RNA biosynthetic process
0.54	GO:0030516	regulation of axon extension
0.54	GO:0001709	cell fate determination
0.51	GO:0034250	positive regulation of cellular amide metabolic process
0.50	GO:0030182	neuron differentiation

0.64	GO:0043565	sequence-specific DNA binding
0.59	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.57	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|Q6YLH7|Q6YLH7_DANRE
Caveolin
Search

CAV3

0.84

Caveolin

0.85	GO:0070836	caveola assembly
0.78	GO:0046716	muscle cell cellular homeostasis
0.65	GO:0023051	regulation of signaling
0.58	GO:0051001	negative regulation of nitric-oxide synthase activity
0.58	GO:0007520	myoblast fusion
0.57	GO:1900826	negative regulation of membrane depolarization during cardiac muscle cell action potential
0.57	GO:0060299	negative regulation of sarcomere organization
0.57	GO:0031623	receptor internalization
0.56	GO:0060306	regulation of membrane repolarization
0.56	GO:0014706	striated muscle tissue development

0.77	GO:0044325	ion channel binding
0.74	GO:0032947	protein complex scaffold activity
0.56	GO:0071253	connexin binding
0.54	GO:0099106	ion channel regulator activity
0.54	GO:0043014	alpha-tubulin binding
0.53	GO:0017080	sodium channel regulator activity
0.52	GO:0008022	protein C-terminus binding
0.48	GO:0032403	protein complex binding
0.46	GO:0050998	nitric-oxide synthase binding
0.44	GO:0016248	channel inhibitor activity

0.84	GO:0005901	caveola
0.74	GO:0000139	Golgi membrane
0.57	GO:0042383	sarcolemma
0.52	GO:0016010	dystrophin-associated glycoprotein complex
0.49	GO:0005783	endoplasmic reticulum
0.42	GO:0031982	vesicle
0.41	GO:0030054	cell junction
0.40	GO:0097223	sperm part
0.40	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005929	cilium

tr|Q6YLH9|Q6YLH9_DANRE
Caveolin
Search

CAV1

0.82

Caveolin

0.85	GO:0070836	caveola assembly
0.63	GO:0031623	receptor internalization
0.61	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
0.61	GO:0051001	negative regulation of nitric-oxide synthase activity
0.60	GO:0046716	muscle cell cellular homeostasis
0.60	GO:0098901	regulation of cardiac muscle cell action potential
0.59	GO:0060306	regulation of membrane repolarization
0.59	GO:0031295	T cell costimulation
0.59	GO:0086004	regulation of cardiac muscle cell contraction
0.59	GO:0014706	striated muscle tissue development

0.66	GO:0044325	ion channel binding
0.63	GO:0032947	protein complex scaffold activity
0.57	GO:0099106	ion channel regulator activity
0.56	GO:0050998	nitric-oxide synthase binding
0.52	GO:0048365	Rac GTPase binding
0.52	GO:0051117	ATPase binding
0.52	GO:0016248	channel inhibitor activity
0.51	GO:0016504	peptidase activator activity
0.50	GO:0030674	protein binding, bridging
0.49	GO:0019901	protein kinase binding

0.84	GO:0005901	caveola
0.74	GO:0000139	Golgi membrane
0.53	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex
0.53	GO:0002080	acrosomal membrane
0.53	GO:0005768	endosome
0.51	GO:0005925	focal adhesion
0.50	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0030315	T-tubule
0.48	GO:0005929	cilium
0.48	GO:0005938	cell cortex

tr|Q6YLV7|Q6YLV7_DANRE
Krueppel-like factor 15
Search

0.87	Kruppel like factor 15

0.54	GO:0003299	muscle hypertrophy in response to stress
0.53	GO:0014887	cardiac muscle adaptation
0.53	GO:2000757	negative regulation of peptidyl-lysine acetylation
0.53	GO:0003300	cardiac muscle hypertrophy
0.53	GO:0072112	glomerular visceral epithelial cell differentiation
0.51	GO:0010001	glial cell differentiation
0.50	GO:0015758	glucose transport
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II
0.37	GO:1901653	cellular response to peptide
0.34	GO:0006366	transcription by RNA polymerase II

0.51	GO:0003676	nucleic acid binding
0.42	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding

0.43	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|Q6YMR2|Q6YMR2_DANRE
MCG1346-like protein
Search

PHF5A

0.93	PHD finger-like domain-containing protein 5A-like

0.74	GO:0000398	mRNA splicing, via spliceosome
0.45	GO:0045893	positive regulation of transcription, DNA-templated
0.39	GO:0006351	transcription, DNA-templated

0.41	GO:0003700	DNA binding transcription factor activity
0.39	GO:0003723	RNA binding
0.38	GO:0003677	DNA binding
0.37	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding

0.84	GO:0005689	U12-type spliceosomal complex
0.81	GO:0005686	U2 snRNP
0.76	GO:0016363	nuclear matrix
0.72	GO:0016607	nuclear speck
0.70	GO:0071011	precatalytic spliceosome
0.67	GO:0071013	catalytic step 2 spliceosome
0.41	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

tr|Q6ZM12|Q6ZM12_DANRE
Novel beta globin
Search

0.73	Hemoglobin cathodic subunit beta

0.79	GO:0015671	oxygen transport
0.37	GO:0030097	hemopoiesis
0.36	GO:0034101	erythrocyte homeostasis
0.36	GO:0010999	regulation of eIF2 alpha phosphorylation by heme
0.35	GO:0048468	cell development
0.35	GO:0098869	cellular oxidant detoxification
0.34	GO:0070293	renal absorption
0.34	GO:0045646	regulation of erythrocyte differentiation
0.34	GO:0070527	platelet aggregation
0.34	GO:0045639	positive regulation of myeloid cell differentiation

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.38	GO:0031720	haptoglobin binding
0.37	GO:0030492	hemoglobin binding
0.35	GO:0004601	peroxidase activity

0.83	GO:0005833	hemoglobin complex
0.37	GO:0031838	haptoglobin-hemoglobin complex
0.35	GO:0043209	myelin sheath
0.35	GO:0005615	extracellular space
0.34	GO:1903561	extracellular vesicle

0.35	EC:1.11.1.7	GO:0004601
0.35	KEGG:R03532	GO:0004601

tr|Q6ZM13|Q6ZM13_DANRE
Novel alpha globin
Search

0.71	Hemoglobin embryonic subunit alpha

0.79	GO:0015671	oxygen transport
0.35	GO:0030097	hemopoiesis
0.34	GO:0001666	response to hypoxia
0.34	GO:0034101	erythrocyte homeostasis
0.34	GO:0071695	anatomical structure maturation
0.34	GO:0048469	cell maturation
0.33	GO:0000122	negative regulation of transcription by RNA polymerase II

0.79	GO:0019825	oxygen binding
0.79	GO:0005344	oxygen carrier activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding

0.83	GO:0005833	hemoglobin complex
0.30	GO:0016020	membrane

tr|Q6ZM17|Q6ZM17_DANRE
Novel protein similar to zebrafish hemoglobin alpha-adult 1 (Hbaa1)
Search

0.69	Hemoglobin embryonic subunit alpha

0.79	GO:0015671	oxygen transport
0.35	GO:0001666	response to hypoxia
0.34	GO:0030097	hemopoiesis

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding

0.82	GO:0005833	hemoglobin complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q6ZM19|IF6_DANRE
Eukaryotic translation initiation factor 6
Search

EIF6

0.68	Eukaryotic translation initiation factor 6

0.79	GO:0042256	mature ribosome assembly
0.72	GO:0042273	ribosomal large subunit biogenesis
0.71	GO:0006413	translational initiation
0.62	GO:0000054	ribosomal subunit export from nucleus
0.56	GO:0045652	regulation of megakaryocyte differentiation
0.55	GO:0006110	regulation of glycolytic process
0.53	GO:0042304	regulation of fatty acid biosynthetic process
0.53	GO:0032868	response to insulin
0.53	GO:2000377	regulation of reactive oxygen species metabolic process
0.50	GO:0045727	positive regulation of translation

0.74	GO:0043023	ribosomal large subunit binding
0.74	GO:0043022	ribosome binding
0.72	GO:0003743	translation initiation factor activity
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.70	GO:0005730	nucleolus
0.56	GO:0005638	lamin filament
0.47	GO:0005737	cytoplasm
0.45	GO:0030687	preribosome, large subunit precursor
0.38	GO:0005654	nucleoplasm
0.36	GO:0070062	extracellular exosome

0.32

GO:0016787

tr|Q6ZM22|Q6ZM22_DANRE
Zinc finger CCCH-type containing 10
Search

ZC3H10

0.84	zinc finger CCCH domain-containing protein 10

0.55	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA
0.30	GO:0008152	metabolic process

0.54	GO:0035198	miRNA binding
0.53	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.32	GO:0050110	mucinaminylserine mucinaminidase activity
0.32	GO:0033926	glycopeptide alpha-N-acetylgalactosaminidase activity
0.32	GO:0030246	carbohydrate binding

0.34	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm

0.32	EC:3.2.1.97	GO:0050110
0.32	KEGG:R04527	GO:0050110

tr|Q6ZM23|Q6ZM23_DANRE
Cytochrome c oxidase subunit VIc
Search

COX6C

0.96	Cytochrome c oxidase polypeptide VIc

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.34	GO:0006119	oxidative phosphorylation
0.34	GO:0009060	aerobic respiration

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.48	GO:0031966	mitochondrial membrane
0.48	GO:0019866	organelle inner membrane
0.38	GO:0045277	respiratory chain complex IV
0.35	GO:0098798	mitochondrial protein complex
0.30	GO:0016021	integral component of membrane

0.65

EC:1.9

GO:0016675

tr|Q6ZM24|Q6ZM24_DANRE
Translocase of outer mitochondrial membrane 34
Search

TOMM34

0.94	Translocase of outer mitochondrial membrane 34

0.79

GO:0006626

protein targeting to mitochondrion

0.78

GO:0031072

heat shock protein binding

0.78	GO:0005741	mitochondrial outer membrane
0.70	GO:0005654	nucleoplasm
0.69	GO:0005829	cytosol

sp|Q6ZM28|HRG1B_DANRE
Heme transporter hrg1-B
Search

SLC48A1

0.97	Heme transporter hrg1-B

0.77	GO:0015886	heme transport
0.45	GO:0048821	erythrocyte development

0.77	GO:0015232	heme transporter activity
0.45	GO:0020037	heme binding
0.33	GO:0005515	protein binding

0.55	GO:0005765	lysosomal membrane
0.53	GO:0010008	endosome membrane
0.41	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q6ZM32|Q6ZM32_DANRE
ADP-ribosylation factor-like 8
Search

ARL5B

0.95	ADP ribosylation factor like GTPase 5B

0.60	GO:1903292	protein localization to Golgi membrane
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003779	actin binding
0.33	GO:0003735	structural constituent of ribosome

0.45	GO:0005622	intracellular
0.32	GO:1990904	ribonucleoprotein complex
0.32	GO:0043228	non-membrane-bounded organelle
0.30	GO:0016020	membrane

tr|Q6ZM33|Q6ZM33_DANRE
Histamine receptor H3
Search

HRH3

0.91	Histamine H3 receptor long form

0.70	GO:0001505	regulation of neurotransmitter levels
0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.49	GO:0007194	negative regulation of adenylate cyclase activity
0.47	GO:0014050	negative regulation of glutamate secretion
0.46	GO:0014063	negative regulation of serotonin secretion
0.46	GO:0014061	regulation of norepinephrine secretion
0.43	GO:0050890	cognition
0.36	GO:0014053	negative regulation of gamma-aminobutyric acid secretion
0.36	GO:0042756	drinking behavior
0.35	GO:0042755	eating behavior

0.85	GO:0004969	histamine receptor activity
0.32	GO:0008144	drug binding

0.36	GO:0097458	neuron part
0.35	GO:0043209	myelin sheath
0.35	GO:0005886	plasma membrane
0.34	GO:0044456	synapse part
0.34	GO:0120025	plasma membrane bounded cell projection
0.30	GO:0016021	integral component of membrane

tr|Q6ZM34|Q6ZM34_DANRE
Vacuolar protein sorting 35 homolog (S. cerevisiae)
Search

VPS35

0.73	Vacuolar protein sorting-associated protein 35

0.78	GO:0042147	retrograde transport, endosome to Golgi
0.64	GO:0015031	protein transport
0.59	GO:1903336	negative regulation of vacuolar transport
0.59	GO:1902822	regulation of late endosome to lysosome transport
0.58	GO:0099074	mitochondrion to lysosome transport
0.58	GO:0060161	positive regulation of dopamine receptor signaling pathway
0.57	GO:1902950	regulation of dendritic spine maintenance
0.57	GO:0043653	mitochondrial fragmentation involved in apoptotic process
0.57	GO:2000331	regulation of terminal button organization
0.56	GO:0045056	transcytosis

0.58	GO:0031748	D1 dopamine receptor binding
0.43	GO:0008565	protein transporter activity
0.34	GO:0004672	protein kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008144	drug binding

0.82	GO:0030906	retromer, cargo-selective complex
0.67	GO:0005829	cytosol
0.58	GO:0099073	mitochondrion-derived vesicle
0.57	GO:0097422	tubular endosome
0.52	GO:0005769	early endosome
0.52	GO:0005764	lysosome
0.51	GO:0010008	endosome membrane
0.49	GO:0014069	postsynaptic density
0.48	GO:0043025	neuronal cell body
0.48	GO:0048471	perinuclear region of cytoplasm

tr|Q6ZM36|Q6ZM36_DANRE
Origin recognition complex, subunit 6
Search

ORC6

0.95	Origin recognition complex subunit 6

0.66	GO:0006260	DNA replication
0.58	GO:0051782	negative regulation of cell division
0.36	GO:0009555	pollen development
0.35	GO:0000082	G1/S transition of mitotic cell cycle

0.54	GO:0003677	DNA binding
0.34	GO:0005515	protein binding

0.84	GO:0005664	nuclear origin of replication recognition complex
0.58	GO:0001650	fibrillar center
0.34	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

tr|Q6ZM39|Q6ZM39_DANRE
Ladybird homeobox 1a
Search

LBX1

0.97	Ladybird homeobox 1 transcription factor

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0021519	spinal cord association neuron specification
0.56	GO:0010468	regulation of gene expression
0.54	GO:0048664	neuron fate determination
0.53	GO:0021522	spinal cord motor neuron differentiation
0.52	GO:0001947	heart looping
0.51	GO:0045665	negative regulation of neuron differentiation
0.50	GO:0008285	negative regulation of cell proliferation
0.46	GO:0061061	muscle structure development

0.64	GO:0043565	sequence-specific DNA binding
0.43	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.30	GO:0016021	integral component of membrane

tr|Q6ZM49|Q6ZM49_DANRE
CTTNBP2 N-terminal-like b
Search

CTTNBP2NL

0.91	Coiled-coil domain-containing protein 88B

0.82	GO:0032410	negative regulation of transporter activity
0.81	GO:0034763	negative regulation of transmembrane transport
0.70	GO:0006470	protein dephosphorylation

0.84

GO:0051721

protein phosphatase 2A binding

0.71	GO:0015629	actin cytoskeleton
0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q6ZM51|FICD_DANRE
Adenosine monophosphate-protein transferase FICD
Search

FICD

0.90	FIC domain containing

0.71	GO:1903894	regulation of IRE1-mediated unfolded protein response
0.69	GO:0018117	protein adenylylation
0.63	GO:0034976	response to endoplasmic reticulum stress

0.69	GO:0070733	protein adenylyltransferase activity
0.69	GO:0030544	Hsp70 protein binding
0.61	GO:0051087	chaperone binding
0.60	GO:0042803	protein homodimerization activity
0.47	GO:0032559	adenyl ribonucleotide binding
0.46	GO:0008144	drug binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding

0.62

GO:0030176

integral component of endoplasmic reticulum membrane

tr|Q6ZM61|Q6ZM61_DANRE
Ube2g1 protein
Search

0.93	Ubiquitin-conjugating enzyme E2G 1

0.47	GO:0000209	protein polyubiquitination
0.44	GO:0044257	cellular protein catabolic process
0.40	GO:0043632	modification-dependent macromolecule catabolic process
0.37	GO:0006508	proteolysis

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0031625	ubiquitin protein ligase binding
0.44	GO:0004842	ubiquitin-protein transferase activity
0.44	GO:0061650	ubiquitin-like protein conjugating enzyme activity
0.41	GO:0061659	ubiquitin-like protein ligase activity

0.35

GO:0005737

cytoplasm

0.44

GO:0004842

tr|Q6ZM62|Q6ZM62_DANRE
Actin-related protein 2/3 complex subunit 3
Search

ARPC3

0.73	Actin-related protein 2/3 complex subunit 3

0.80	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.38	GO:1990090	cellular response to nerve growth factor stimulus
0.35	GO:0070358	actin polymerization-dependent cell motility
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.35	GO:0048013	ephrin receptor signaling pathway
0.33	GO:0061024	membrane organization

0.68	GO:0003779	actin binding
0.48	GO:0005200	structural constituent of cytoskeleton
0.47	GO:0032403	protein complex binding

0.79	GO:0005885	Arp2/3 protein complex
0.51	GO:0030027	lamellipodium
0.46	GO:0005737	cytoplasm
0.40	GO:0061850	growth cone leading edge
0.38	GO:0031941	filamentous actin
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|Q6ZM63|GPN3_DANRE
GPN-loop GTPase 3
Search

GPN3

0.88	GPN-loop GTPase 3

0.71	GO:1990022	RNA polymerase III complex localization to nucleus
0.70	GO:0044376	RNA polymerase II complex import to nucleus
0.44	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.35	GO:0006338	chromatin remodeling

0.55	GO:0003924	GTPase activity
0.44	GO:0032550	purine ribonucleoside binding
0.44	GO:0019001	guanyl nucleotide binding
0.41	GO:0032555	purine ribonucleotide binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0030554	adenyl nucleotide binding
0.36	GO:0008144	drug binding
0.35	GO:0005515	protein binding

0.54	GO:0043234	protein complex
0.42	GO:0015629	actin cytoskeleton
0.41	GO:0044430	cytoskeletal part
0.35	GO:0000228	nuclear chromosome
0.30	GO:0016020	membrane

tr|Q6ZM67|Q6ZM67_DANRE
Glutamate receptor, ionotropic, N-methyl D-aspartate 1b
Search

GRIN1

0.92	Glutamate ionotropic receptor NMDA type subunit 1

0.80	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.60	GO:0034220	ion transmembrane transport
0.56	GO:0018964	propylene metabolic process
0.55	GO:0021586	pons maturation
0.55	GO:1905429	response to glycine
0.55	GO:0001661	conditioned taste aversion
0.54	GO:0060134	prepulse inhibition
0.54	GO:0043278	response to morphine
0.54	GO:0008355	olfactory learning

0.82	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.56	GO:0016594	glycine binding
0.54	GO:0016595	glutamate binding
0.54	GO:0099094	ligand-gated cation channel activity
0.52	GO:0022843	voltage-gated cation channel activity
0.51	GO:0005262	calcium channel activity
0.51	GO:1904315	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
0.49	GO:0005516	calmodulin binding
0.47	GO:0005102	receptor binding

0.79	GO:0045211	postsynaptic membrane
0.75	GO:0030054	cell junction
0.57	GO:0017146	NMDA selective glutamate receptor complex
0.52	GO:0043197	dendritic spine
0.52	GO:0014069	postsynaptic density
0.51	GO:0008021	synaptic vesicle
0.48	GO:0009986	cell surface
0.46	GO:0005783	endoplasmic reticulum
0.41	GO:0044422	organelle part
0.38	GO:0043083	synaptic cleft

tr|Q6ZM69|Q6ZM69_DANRE
Ectonucleoside triphosphate diphosphohydrolase 2a, tandem duplicate 2 (Fragment)
Search

ENTPD2

0.92	Ectonucleoside triphosphate diphosphohydrolase 2 b

0.53	GO:0009137	purine nucleoside diphosphate catabolic process
0.53	GO:0009191	ribonucleoside diphosphate catabolic process
0.50	GO:0030168	platelet activation
0.45	GO:0007186	G-protein coupled receptor signaling pathway
0.45	GO:0009179	purine ribonucleoside diphosphate metabolic process
0.43	GO:0045471	response to ethanol
0.42	GO:0071405	cellular response to methanol
0.42	GO:0046688	response to copper ion
0.35	GO:0034656	nucleobase-containing small molecule catabolic process
0.35	GO:0035457	cellular response to interferon-alpha

0.51	GO:0016787	hydrolase activity
0.35	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.51	GO:0005605	basal lamina
0.39	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0044297	cell body
0.34	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0009986	cell surface
0.33	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.51

GO:0016787

tr|Q6ZM71|Q6ZM71_DANRE
Arrestin domain containing 1a
Search

ARRDC1

0.91	Arrestin domain-containing protein 1

0.60	GO:0007165	signal transduction
0.54	GO:0140112	extracellular vesicle biogenesis
0.53	GO:0006858	extracellular transport
0.52	GO:0045746	negative regulation of Notch signaling pathway
0.47	GO:0006511	ubiquitin-dependent protein catabolic process
0.47	GO:0016567	protein ubiquitination
0.44	GO:0015031	protein transport
0.37	GO:0045892	negative regulation of transcription, DNA-templated
0.33	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination
0.33	GO:0051666	actin cortical patch localization

0.55	GO:1990756	protein binding, bridging involved in substrate recognition for ubiquitination
0.55	GO:1990763	arrestin family protein binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0042802	identical protein binding
0.33	GO:0003779	actin binding
0.32	GO:0004930	G-protein coupled receptor activity
0.32	GO:0003682	chromatin binding
0.32	GO:0050660	flavin adenine dinucleotide binding
0.32	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors

0.50	GO:1903561	extracellular vesicle
0.47	GO:0031410	cytoplasmic vesicle
0.40	GO:0005886	plasma membrane
0.35	GO:0005634	nucleus
0.35	GO:0005615	extracellular space
0.32	GO:0030479	actin cortical patch
0.32	GO:0034708	methyltransferase complex
0.32	GO:1905369	endopeptidase complex
0.32	GO:0043234	protein complex
0.32	GO:0043233	organelle lumen

0.32

EC:1.1

GO:0016614

tr|Q6ZM78|Q6ZM78_DANRE
Splicing factor 3B subunit 10
Search

SF3B5

0.92	splicing factor 3B subunit 5

0.75	GO:0000398	mRNA splicing, via spliceosome
0.42	GO:0007283	spermatogenesis
0.35	GO:0038003	opioid receptor signaling pathway
0.34	GO:0007218	neuropeptide signaling pathway

0.35	GO:0004979	beta-endorphin receptor activity
0.34	GO:0003723	RNA binding

0.56	GO:0005689	U12-type spliceosomal complex
0.47	GO:0071011	precatalytic spliceosome
0.47	GO:0005654	nucleoplasm
0.46	GO:0005686	U2 snRNP
0.30	GO:0031224	intrinsic component of membrane

tr|Q6ZM82|Q6ZM82_DANRE
Component of oligomeric golgi complex 2
Search

COG2

0.92	Component of oligomeric golgi complex 2

0.80	GO:0007030	Golgi organization
0.64	GO:0015031	protein transport
0.54	GO:0006891	intra-Golgi vesicle-mediated transport
0.34	GO:0006888	ER to Golgi vesicle-mediated transport

0.49	GO:0008565	protein transporter activity
0.37	GO:0032403	protein complex binding

0.55	GO:0017119	Golgi transport complex
0.52	GO:0005795	Golgi stack
0.36	GO:0005829	cytosol
0.35	GO:0000139	Golgi membrane
0.34	GO:0005802	trans-Golgi network
0.30	GO:0016021	integral component of membrane

tr|Q6ZM83|Q6ZM83_DANRE
PiggyBac transposable element-derived 5
Search

PGBD5

0.97	PiggyBac transposable element-derived protein 5

0.63	GO:0032196	transposition
0.57	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.59

GO:0004519

endonuclease activity

0.55	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|Q6ZM84|Q6ZM84_DANRE
Regulator of G-protein-signaling 9b
Search

RGS9

0.94	Regulator of G-protein signaling 9

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.61	GO:0035556	intracellular signal transduction
0.44	GO:0043547	positive regulation of GTPase activity
0.39	GO:0007601	visual perception
0.38	GO:0043627	response to estrogen
0.38	GO:0009968	negative regulation of signal transduction
0.38	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.36	GO:0007399	nervous system development
0.33	GO:0006457	protein folding

0.63	GO:0004871	signal transducer activity
0.44	GO:0005096	GTPase activator activity
0.36	GO:0032403	protein complex binding

0.80	GO:1905360	GTPase complex
0.79	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.65	GO:0098797	plasma membrane protein complex
0.52	GO:0001917	photoreceptor inner segment
0.52	GO:0001750	photoreceptor outer segment
0.36	GO:0060170	ciliary membrane
0.36	GO:0005737	cytoplasm
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q6ZM86|GRD2I_DANRE
Delphilin
Search

GRID2IP

0.89	Glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, a

0.79	GO:0060292	long term synaptic depression
0.43	GO:2001141	regulation of RNA biosynthetic process
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.42	GO:0010468	regulation of gene expression
0.42	GO:0007216	G-protein coupled glutamate receptor signaling pathway
0.39	GO:0055085	transmembrane transport
0.39	GO:0030036	actin cytoskeleton organization

0.40	GO:0022857	transmembrane transporter activity
0.37	GO:0005515	protein binding

0.75	GO:0043197	dendritic spine
0.45	GO:0005634	nucleus
0.42	GO:0045211	postsynaptic membrane
0.41	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

sp|Q6ZM89|RH42A_DANRE
Rho GTPase-activating protein 42
Search

ARHGAP42

0.96	Rho GTPase-activating protein 42

0.73	GO:0043547	positive regulation of GTPase activity
0.59	GO:0007165	signal transduction
0.55	GO:1904694	negative regulation of vascular smooth muscle contraction
0.53	GO:0003085	negative regulation of systemic arterial blood pressure
0.53	GO:0035024	negative regulation of Rho protein signal transduction

0.73

GO:0005096

GTPase activator activity

0.30

GO:0016021

integral component of membrane

tr|Q6ZM98|Q6ZM98_DANRE
Guanylate cyclase activating protein 4
Search

GUCA1C

0.96	Guanylate cyclase activating protein 4

0.72	GO:0031284	positive regulation of guanylate cyclase activity
0.59	GO:0007601	visual perception
0.35	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.34	GO:0006468	protein phosphorylation
0.33	GO:0007165	signal transduction
0.32	GO:0055114	oxidation-reduction process

0.73	GO:0008048	calcium sensitive guanylate cyclase activator activity
0.70	GO:0005509	calcium ion binding
0.34	GO:0004672	protein kinase activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0016174	NAD(P)H oxidase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0001750	photoreceptor outer segment
0.34	GO:0060170	ciliary membrane
0.30	GO:0016021	integral component of membrane

0.34

EC:1.6.3.1

GO:0016174

sp|Q701R2|SIAT2_DANRE
Beta-galactoside alpha-2,6-sialyltransferase 2
Search

ST6GAL2

0.97	Beta-galactosidase alpha-2,6 sialyltransferase

0.83	GO:0097503	sialylation
0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.60	GO:0006464	cellular protein modification process
0.50	GO:0009311	oligosaccharide metabolic process
0.34	GO:0006054	N-acetylneuraminate metabolic process
0.34	GO:0040007	growth
0.34	GO:0007275	multicellular organism development

0.83

GO:0008373

sialyltransferase activity

0.47	GO:0005794	Golgi apparatus
0.44	GO:0098588	bounding membrane of organelle
0.43	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:2.4.99

GO:0008373

sp|Q708S3|ASI4B_DANRE
Acid-sensing ion channel 4
Search

ASIC4

0.96	Amiloride-sensitive cation channel 4 b

0.74	GO:0035725	sodium ion transmembrane transport
0.43	GO:0003026	regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback
0.43	GO:0050915	sensory perception of sour taste
0.41	GO:0035418	protein localization to synapse
0.41	GO:0009268	response to pH
0.41	GO:0050974	detection of mechanical stimulus involved in sensory perception
0.41	GO:0051965	positive regulation of synapse assembly
0.40	GO:0019229	regulation of vasoconstriction
0.40	GO:0007605	sensory perception of sound
0.39	GO:0007602	phototransduction

0.78	GO:0005272	sodium channel activity
0.52	GO:0099094	ligand-gated cation channel activity
0.33	GO:0005515	protein binding

0.40	GO:0043197	dendritic spine
0.40	GO:0005887	integral component of plasma membrane
0.40	GO:0043025	neuronal cell body
0.38	GO:0045177	apical part of cell

sp|Q708S4|ASI4A_DANRE
Acid-sensing ion channel 4
Search

ASIC4

0.97	Amiloride-sensitive cation channel 4 b

0.75	GO:0035725	sodium ion transmembrane transport
0.37	GO:0070207	protein homotrimerization
0.37	GO:0071467	cellular response to pH
0.36	GO:0050915	sensory perception of sour taste
0.36	GO:0046929	negative regulation of neurotransmitter secretion
0.36	GO:0010447	response to acidic pH
0.35	GO:0008306	associative learning
0.35	GO:0007613	memory
0.35	GO:0042391	regulation of membrane potential
0.35	GO:0070588	calcium ion transmembrane transport

0.79	GO:0005272	sodium channel activity
0.51	GO:0099094	ligand-gated cation channel activity
0.33	GO:0005515	protein binding

0.39	GO:0045177	apical part of cell
0.39	GO:0005887	integral component of plasma membrane
0.35	GO:0009986	cell surface
0.35	GO:0045202	synapse
0.34	GO:0005794	Golgi apparatus
0.34	GO:0043198	dendritic shaft
0.34	GO:0044309	neuron spine

sp|Q708S5|ASIC2_DANRE
Acid-sensing ion channel 2
Search

ASIC2

0.90	Amiloride-sensitive sodium channel subunit alpha

0.76	GO:0035725	sodium ion transmembrane transport
0.58	GO:0050915	sensory perception of sour taste
0.53	GO:0010447	response to acidic pH
0.51	GO:0003026	regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback
0.50	GO:0042391	regulation of membrane potential
0.49	GO:0051049	regulation of transport
0.48	GO:0035418	protein localization to synapse
0.48	GO:0050974	detection of mechanical stimulus involved in sensory perception
0.47	GO:0071467	cellular response to pH
0.47	GO:0051965	positive regulation of synapse assembly

0.80	GO:0005272	sodium channel activity
0.74	GO:0099094	ligand-gated cation channel activity
0.37	GO:0005515	protein binding

0.49	GO:0045202	synapse
0.47	GO:0044309	neuron spine
0.46	GO:0043025	neuronal cell body
0.46	GO:0005887	integral component of plasma membrane
0.46	GO:0030425	dendrite
0.42	GO:0005794	Golgi apparatus
0.34	GO:0009986	cell surface

sp|Q708S6|ASI1C_DANRE
Acid-sensing ion channel 1C
Search

ASIC1

0.87	Amiloride-sensitive sodium channel subunit beta

0.77	GO:0035725	sodium ion transmembrane transport
0.53	GO:0050915	sensory perception of sour taste
0.52	GO:0046929	negative regulation of neurotransmitter secretion
0.51	GO:0071467	cellular response to pH
0.50	GO:0010447	response to acidic pH
0.50	GO:0008306	associative learning
0.49	GO:0007613	memory
0.47	GO:0042391	regulation of membrane potential
0.47	GO:0070588	calcium ion transmembrane transport
0.42	GO:0070207	protein homotrimerization

0.84	GO:0015280	ligand-gated sodium channel activity
0.35	GO:0005515	protein binding
0.34	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity
0.33	GO:0051287	NAD binding

0.47	GO:0005887	integral component of plasma membrane
0.46	GO:0045202	synapse
0.45	GO:0005794	Golgi apparatus
0.36	GO:0009986	cell surface
0.35	GO:0097458	neuron part
0.34	GO:0016514	SWI/SNF complex
0.34	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0009331	glycerol-3-phosphate dehydrogenase complex

0.34	EC:1.1.1.8 EC:1.1.1.94	GO:0004367
0.34	KEGG:R00842	GO:0004367

sp|Q708S7|ASI1A_DANRE
Acid-sensing ion channel 1A
Search

ASIC1

0.88	Amiloride-sensitive sodium channel subunit beta

0.77	GO:0035725	sodium ion transmembrane transport
0.53	GO:0050915	sensory perception of sour taste
0.52	GO:0071467	cellular response to pH
0.52	GO:0046929	negative regulation of neurotransmitter secretion
0.50	GO:0010447	response to acidic pH
0.50	GO:0008306	associative learning
0.49	GO:0007613	memory
0.47	GO:0042391	regulation of membrane potential
0.47	GO:0070588	calcium ion transmembrane transport
0.43	GO:0070207	protein homotrimerization

0.85	GO:0015280	ligand-gated sodium channel activity
0.35	GO:0005515	protein binding
0.34	GO:0005248	voltage-gated sodium channel activity
0.34	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity
0.33	GO:0051287	NAD binding

0.47	GO:0005887	integral component of plasma membrane
0.46	GO:0045202	synapse
0.45	GO:0005794	Golgi apparatus
0.36	GO:0009986	cell surface
0.35	GO:0097458	neuron part
0.34	GO:0016514	SWI/SNF complex
0.34	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0009331	glycerol-3-phosphate dehydrogenase complex

0.34	EC:1.1.1.8 EC:1.1.1.94	GO:0004367
0.34	KEGG:R00842	GO:0004367

sp|Q708S8|ASI1B_DANRE
Acid-sensing ion channel 1B
Search

0.86	Amiloride-sensitive sodium channel subunit beta

0.77	GO:0035725	sodium ion transmembrane transport
0.52	GO:0050915	sensory perception of sour taste
0.51	GO:0046929	negative regulation of neurotransmitter secretion
0.50	GO:0071467	cellular response to pH
0.49	GO:0010447	response to acidic pH
0.49	GO:0008306	associative learning
0.48	GO:0007613	memory
0.46	GO:0042391	regulation of membrane potential
0.46	GO:0070588	calcium ion transmembrane transport
0.42	GO:0070207	protein homotrimerization

0.85	GO:0015280	ligand-gated sodium channel activity
0.34	GO:0005248	voltage-gated sodium channel activity
0.34	GO:0005515	protein binding

0.47	GO:0005887	integral component of plasma membrane
0.45	GO:0045202	synapse
0.44	GO:0005794	Golgi apparatus
0.36	GO:0009986	cell surface
0.34	GO:0043198	dendritic shaft
0.34	GO:0044309	neuron spine

tr|Q70X92|Q70X92_DANRE
Ankyrin repeat and SOCS box containing protein a
Search

0.76	Ankyrin repeat and SOCS box containing protein a

0.67	GO:0016567	protein ubiquitination
0.58	GO:0007221	positive regulation of transcription of Notch receptor target
0.57	GO:0035556	intracellular signal transduction
0.56	GO:0045747	positive regulation of Notch signaling pathway
0.40	GO:0045732	positive regulation of protein catabolic process
0.36	GO:0009116	nucleoside metabolic process
0.35	GO:0006468	protein phosphorylation
0.35	GO:0070682	proteasome regulatory particle assembly
0.34	GO:0006508	proteolysis
0.33	GO:0034765	regulation of ion transmembrane transport

0.37	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.37	GO:0019899	enzyme binding
0.36	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0004672	protein kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0043168	anion binding
0.34	GO:0008144	drug binding
0.34	GO:0005216	ion channel activity
0.34	GO:0005509	calcium ion binding
0.33	GO:0003950	NAD+ ADP-ribosyltransferase activity

0.43	GO:0005622	intracellular
0.35	GO:1902494	catalytic complex
0.34	GO:0043227	membrane-bounded organelle
0.33	GO:0043234	protein complex
0.32	GO:0043228	non-membrane-bounded organelle
0.32	GO:0044422	organelle part
0.30	GO:0016020	membrane

0.37	EC:2.3.1.225	GO:0019706
0.36	KEGG:R03876	GO:0004842

tr|Q70ZY9|Q70ZY9_DANRE
HIC1 protein
Search

HIC1

0.93	Hypermethylated in cancer 1

0.76	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.70	GO:0000122	negative regulation of transcription by RNA polymerase II
0.39	GO:0030178	negative regulation of Wnt signaling pathway
0.39	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator
0.37	GO:0007275	multicellular organism development
0.37	GO:0016055	Wnt signaling pathway
0.35	GO:0006351	transcription, DNA-templated

0.56	GO:0003700	DNA binding transcription factor activity
0.51	GO:0003676	nucleic acid binding
0.39	GO:0042826	histone deacetylase binding
0.37	GO:0046872	metal ion binding
0.34	GO:0008022	protein C-terminus binding

0.43	GO:0005622	intracellular
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0043227	membrane-bounded organelle
0.35	GO:0044422	organelle part
0.34	GO:0043228	non-membrane-bounded organelle

tr|Q71E60|Q71E60_DANRE
AMPA receptor subunit GluR3B
Search

GRIA3

0.95	Glutamate ionotropic receptor AMPA type subunit 3

0.79	GO:0060079	excitatory postsynaptic potential
0.76	GO:0035235	ionotropic glutamate receptor signaling pathway
0.60	GO:0034220	ion transmembrane transport
0.35	GO:0060992	response to fungicide
0.35	GO:0010226	response to lithium ion
0.35	GO:0001919	regulation of receptor recycling

0.81	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.54	GO:0099094	ligand-gated cation channel activity
0.36	GO:0001540	amyloid-beta binding
0.35	GO:0030165	PDZ domain binding

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.56	GO:0032281	AMPA glutamate receptor complex
0.35	GO:0043083	synaptic cleft
0.35	GO:0043198	dendritic shaft
0.35	GO:0043204	perikaryon
0.35	GO:0043195	terminal bouton
0.35	GO:0043197	dendritic spine
0.34	GO:0030666	endocytic vesicle membrane
0.34	GO:0014069	postsynaptic density

sp|Q71MM5|DMRT1_DANRE
Doublesex- and mab-3-related transcription factor 1
Search

DMRT1

0.91	DM domain-containing transcription factor

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0002176	male germ cell proliferation
0.48	GO:0030238	male sex determination
0.48	GO:0008584	male gonad development
0.47	GO:2000020	positive regulation of male gonad development
0.47	GO:1900107	regulation of nodal signaling pathway
0.47	GO:0060903	positive regulation of meiosis I
0.46	GO:0008354	germ cell migration

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0046872	metal ion binding
0.43	GO:0001012	RNA polymerase II regulatory region DNA binding
0.43	GO:0003682	chromatin binding
0.43	GO:0042803	protein homodimerization activity
0.42	GO:0046982	protein heterodimerization activity
0.42	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

sp|Q71N41|GAMT_DANRE
Guanidinoacetate N-methyltransferase
Search

GAMT

0.97	Guanidinoacetate N-methyltransferase A

0.77	GO:0006601	creatine biosynthetic process
0.61	GO:0032259	methylation
0.52	GO:0040014	regulation of multicellular organism growth
0.50	GO:0007283	spermatogenesis
0.49	GO:0009887	animal organ morphogenesis
0.45	GO:0046498	S-adenosylhomocysteine metabolic process
0.45	GO:0046500	S-adenosylmethionine metabolic process
0.36	GO:1990402	embryonic liver development
0.35	GO:0006936	muscle contraction

0.84	GO:0030731	guanidinoacetate N-methyltransferase activity
0.34	GO:0042803	protein homodimerization activity

0.40	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.36	GO:0005737	cytoplasm
0.35	GO:0005902	microvillus
0.30	GO:0016020	membrane

0.84	EC:2.1.1.2	GO:0030731
0.84	KEGG:R01883	GO:0030731

sp|Q71PD7|H2AV_DANRE
Histone H2A.V
Search

sp|Q71SG7|GCNT4_DANRE
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4
Search

GCNT4

0.97	Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4

0.57	GO:0060993	kidney morphogenesis
0.55	GO:0002121	inter-male aggressive behavior
0.54	GO:0048729	tissue morphogenesis
0.53	GO:0042403	thyroid hormone metabolic process
0.50	GO:0002426	immunoglobulin production in mucosal tissue
0.49	GO:0048872	homeostasis of number of cells
0.48	GO:0050892	intestinal absorption
0.39	GO:0006486	protein glycosylation
0.34	GO:0036438	maintenance of lens transparency
0.34	GO:0034116	positive regulation of heterotypic cell-cell adhesion

0.77	GO:0008375	acetylglucosaminyltransferase activity
0.48	GO:0140103	catalytic activity, acting on a glycoprotein

0.38	GO:0000139	Golgi membrane
0.35	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.77

GO:0008375

tr|Q75XT1|Q75XT1_DANRE
Acetylcholine receptor delta subunit
Search

CHRND

0.92	Cholinergic receptor nicotinic delta subunit

0.79	GO:0060079	excitatory postsynaptic potential
0.71	GO:0048630	skeletal muscle tissue growth
0.68	GO:0050881	musculoskeletal movement
0.60	GO:0034220	ion transmembrane transport
0.56	GO:0007271	synaptic transmission, cholinergic
0.55	GO:0035094	response to nicotine
0.55	GO:0007274	neuromuscular synaptic transmission
0.48	GO:0030239	myofibril assembly
0.44	GO:0006812	cation transport
0.38	GO:0006941	striated muscle contraction

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.71	GO:0042166	acetylcholine binding
0.70	GO:0004888	transmembrane signaling receptor activity

0.78	GO:0045211	postsynaptic membrane
0.73	GO:0030054	cell junction
0.73	GO:0005892	acetylcholine-gated channel complex
0.56	GO:0005654	nucleoplasm
0.55	GO:0005829	cytosol

sp|Q76LC6|RBM24_DANRE
RNA-binding protein 24
Search

RBM24

0.88	RNA binding motif protein 24

0.62	GO:0051153	regulation of striated muscle cell differentiation
0.55	GO:0043488	regulation of mRNA stability
0.48	GO:0003228	atrial cardiac muscle tissue development
0.47	GO:0048702	embryonic neurocranium morphogenesis
0.46	GO:0001947	heart looping
0.46	GO:0001756	somitogenesis
0.46	GO:0043484	regulation of RNA splicing
0.45	GO:0007519	skeletal muscle tissue development
0.45	GO:0110020	regulation of actomyosin structure organization
0.44	GO:0072358	cardiovascular system development

0.59	GO:0003723	RNA binding
0.33	GO:0003779	actin binding

0.47	GO:0005829	cytosol
0.46	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|Q789K9|Q789K9_DANRE
Ubiquitin-conjugating enzyme E2A (RAD6 homolog)
Search

UBE2A

0.61	Ubiquitin-conjugating enzyme

0.56	GO:0070979	protein K11-linked ubiquitination
0.56	GO:0033522	histone H2A ubiquitination
0.55	GO:0070936	protein K48-linked ubiquitination
0.55	GO:0051865	protein autoubiquitination
0.53	GO:0009411	response to UV
0.51	GO:0001701	in utero embryonic development
0.49	GO:0060135	maternal process involved in female pregnancy
0.49	GO:0008284	positive regulation of cell proliferation
0.48	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.46	GO:0006281	DNA repair

0.56	GO:0061631	ubiquitin conjugating enzyme activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0043130	ubiquitin binding

0.58	GO:0033503	HULC complex
0.55	GO:0001741	XY body
0.51	GO:0000790	nuclear chromatin
0.40	GO:0005657	replication fork
0.37	GO:0005737	cytoplasm
0.33	GO:0005654	nucleoplasm
0.33	GO:0005886	plasma membrane

tr|Q78AM8|Q78AM8_DANRE
SI:bY184L24.2.1 (Transcription factor spi1)
Search

0.97	Spleen focus forming virus (SFFV) proviral integration oncogene spi1

0.61	GO:0030225	macrophage differentiation
0.60	GO:0030851	granulocyte differentiation
0.60	GO:0045646	regulation of erythrocyte differentiation
0.58	GO:0030218	erythrocyte differentiation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0044027	hypermethylation of CpG island
0.55	GO:0045347	negative regulation of MHC class II biosynthetic process
0.54	GO:0090241	negative regulation of histone H4 acetylation

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0051525	NFAT protein binding
0.51	GO:0035326	enhancer binding
0.51	GO:0001047	core promoter binding
0.50	GO:0001085	RNA polymerase II transcription factor binding
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003690	double-stranded DNA binding
0.34	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.46	GO:0000785	chromatin
0.45	GO:0070013	intracellular organelle lumen
0.34	GO:0005667	transcription factor complex
0.30	GO:0031224	intrinsic component of membrane

tr|Q78AP9|Q78AP9_DANRE
ADP-ribosylation factor 3b
Search

ARF3

0.80	ADP ribosylation factor 3

0.53	GO:1990386	mitotic cleavage furrow ingression
0.50	GO:0016192	vesicle-mediated transport
0.49	GO:0098586	cellular response to virus
0.47	GO:0006878	cellular copper ion homeostasis
0.41	GO:0060292	long term synaptic depression
0.41	GO:0097061	dendritic spine organization
0.41	GO:0002090	regulation of receptor internalization
0.41	GO:1903337	positive regulation of vacuolar transport
0.40	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation
0.40	GO:1902822	regulation of late endosome to lysosome transport

0.64	GO:0005525	GTP binding
0.46	GO:0019904	protein domain specific binding
0.45	GO:0046982	protein heterodimerization activity
0.42	GO:0000287	magnesium ion binding
0.41	GO:1990583	phospholipase D activator activity
0.39	GO:0019003	GDP binding
0.34	GO:0003924	GTPase activity
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0003723	RNA binding

0.51	GO:0005794	Golgi apparatus
0.48	GO:0030017	sarcomere
0.47	GO:0031252	cell leading edge
0.43	GO:0005829	cytosol
0.42	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0043234	protein complex
0.39	GO:0014069	postsynaptic density
0.39	GO:0031982	vesicle
0.39	GO:0045211	postsynaptic membrane
0.38	GO:0043005	neuron projection

tr|Q7SX58|Q7SX58_DANRE
Coronin
Search

CORO1A

0.69

Coronin

0.68	GO:0001845	phagolysosome assembly
0.65	GO:0030595	leukocyte chemotaxis
0.64	GO:0030036	actin cytoskeleton organization
0.57	GO:0061502	early endosome to recycling endosome transport
0.57	GO:0032796	uropod organization
0.56	GO:0038180	nerve growth factor signaling pathway
0.56	GO:0043320	natural killer cell degranulation
0.55	GO:0031339	negative regulation of vesicle fusion
0.55	GO:0071353	cellular response to interleukin-4
0.54	GO:0048873	homeostasis of number of cells within a tissue

0.73	GO:0051015	actin filament binding
0.55	GO:0032036	myosin heavy chain binding
0.54	GO:0043548	phosphatidylinositol 3-kinase binding
0.53	GO:0003785	actin monomer binding
0.52	GO:0008022	protein C-terminus binding
0.49	GO:0042803	protein homodimerization activity
0.40	GO:0048365	Rac GTPase binding
0.34	GO:0008289	lipid binding
0.34	GO:0003723	RNA binding

0.64	GO:0015629	actin cytoskeleton
0.54	GO:0001891	phagocytic cup
0.54	GO:0001772	immunological synapse
0.53	GO:0030027	lamellipodium
0.52	GO:0045335	phagocytic vesicle
0.51	GO:0005769	early endosome
0.51	GO:0030424	axon
0.51	GO:0030863	cortical cytoskeleton
0.49	GO:0005911	cell-cell junction
0.47	GO:0099513	polymeric cytoskeletal fiber

tr|Q7SX66|Q7SX66_DANRE
Fibroblast growth factor
Search

FGF18

0.62	Fibroblast growth factor

0.75	GO:0010469	regulation of receptor activity
0.74	GO:0008543	fibroblast growth factor receptor signaling pathway
0.55	GO:1904849	positive regulation of cell chemotaxis to fibroblast growth factor
0.55	GO:0001957	intramembranous ossification
0.54	GO:2000544	regulation of endothelial cell chemotaxis to fibroblast growth factor
0.54	GO:0035295	tube development
0.54	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
0.54	GO:0072359	circulatory system development
0.54	GO:2001028	positive regulation of endothelial cell chemotaxis
0.54	GO:0009887	animal organ morphogenesis

0.78	GO:0008083	growth factor activity
0.76	GO:0005104	fibroblast growth factor receptor binding
0.35	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0004713	protein tyrosine kinase activity
0.32	GO:0003676	nucleic acid binding

0.60	GO:0005576	extracellular region
0.47	GO:0005730	nucleolus
0.34	GO:0005764	lysosome

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

tr|Q7SX76|Q7SX76_DANRE
FGF receptor-like protein 1a
Search

FGFRL1

0.95	Fibroblast growth factor receptor like 1

0.52	GO:0001501	skeletal system development
0.51	GO:0008543	fibroblast growth factor receptor signaling pathway
0.50	GO:0060412	ventricular septum morphogenesis
0.50	GO:0003179	heart valve morphogenesis
0.50	GO:0060539	diaphragm development
0.48	GO:0051260	protein homooligomerization
0.48	GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules
0.48	GO:0008285	negative regulation of cell proliferation
0.44	GO:0021592	fourth ventricle development
0.44	GO:0021678	third ventricle development

0.52	GO:0005007	fibroblast growth factor-activated receptor activity
0.50	GO:0008201	heparin binding
0.50	GO:0017134	fibroblast growth factor binding
0.36	GO:0001571	non-tyrosine kinase fibroblast growth factor receptor activity
0.32	GO:0003676	nucleic acid binding

0.51	GO:0044291	cell-cell contact zone
0.48	GO:0030133	transport vesicle
0.46	GO:0005794	Golgi apparatus
0.40	GO:0005886	plasma membrane
0.34	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.33	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

tr|Q7SX78|Q7SX78_DANRE
Sizzled
Search

0.76	Secreted frizzled-related protein 5

0.68	GO:0007275	multicellular organism development
0.65	GO:0016055	Wnt signaling pathway
0.55	GO:0061185	negative regulation of dermatome development
0.55	GO:2000041	negative regulation of planar cell polarity pathway involved in axis elongation
0.55	GO:0042662	negative regulation of mesodermal cell fate specification
0.54	GO:0071481	cellular response to X-ray
0.54	GO:2000035	regulation of stem cell division
0.54	GO:0035413	positive regulation of catenin import into nucleus
0.54	GO:0043508	negative regulation of JUN kinase activity
0.53	GO:0010667	negative regulation of cardiac muscle cell apoptotic process

0.54	GO:0017147	Wnt-protein binding
0.53	GO:0061133	endopeptidase activator activity
0.48	GO:0048018	receptor ligand activity
0.45	GO:0042813	Wnt-activated receptor activity
0.42	GO:0004930	G-protein coupled receptor activity
0.36	GO:0001968	fibronectin binding
0.36	GO:0005178	integrin binding

0.56	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|Q7SX85|SESD1_DANRE
SEC14 domain and spectrin repeat-containing protein 1
Search

SESTD1

0.97	LOW QUALITY PROTEIN: SEC14 domain and spectrin repeat-containing protein 1

0.85	GO:1904878	negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
0.56	GO:0048514	blood vessel morphogenesis

0.81	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.81	GO:0010314	phosphatidylinositol-5-phosphate binding
0.81	GO:0070300	phosphatidic acid binding
0.78	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.78	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.76	GO:0070273	phosphatidylinositol-4-phosphate binding
0.76	GO:0032266	phosphatidylinositol-3-phosphate binding
0.43	GO:0031210	phosphatidylcholine binding
0.43	GO:0001786	phosphatidylserine binding
0.42	GO:0005545	1-phosphatidylinositol binding

0.74	GO:0034704	calcium channel complex
0.72	GO:0045111	intermediate filament cytoskeleton

tr|Q7SX89|Q7SX89_DANRE
SPRY domain-containing 7b
Search

SPRYD7

0.97	SPRY domain-containing protein 7

0.45

GO:0005515

protein binding

0.30

GO:0044425

membrane part

tr|Q7SX91|Q7SX91_DANRE
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
Search

RRS1

0.71	Ribosome biogenesis regulatory protein homolog

0.67	GO:0042254	ribosome biogenesis
0.55	GO:1902570	protein localization to nucleolus
0.53	GO:1901796	regulation of signal transduction by p53 class mediator
0.53	GO:0007080	mitotic metaphase plate congression
0.48	GO:0033750	ribosome localization
0.48	GO:0022618	ribonucleoprotein complex assembly
0.48	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus
0.47	GO:0070925	organelle assembly
0.44	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.43	GO:0002244	hematopoietic progenitor cell differentiation

0.50	GO:0008097	5S rRNA binding
0.34	GO:0005515	protein binding
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.49	GO:0000793	condensed chromosome
0.48	GO:0031974	membrane-enclosed lumen
0.47	GO:0030687	preribosome, large subunit precursor
0.43	GO:0044446	intracellular organelle part
0.40	GO:0005783	endoplasmic reticulum

0.32

GO:0016491

tr|Q7SX92|Q7SX92_DANRE
Beta-synuclein
Search

SNCB

0.91	Gamma-synuclein

0.67	GO:0014059	regulation of dopamine secretion
0.59	GO:0042417	dopamine metabolic process
0.57	GO:0043524	negative regulation of neuron apoptotic process
0.56	GO:0050808	synapse organization
0.54	GO:0007268	chemical synaptic transmission
0.51	GO:0051945	negative regulation of catecholamine uptake involved in synaptic transmission
0.51	GO:0051621	regulation of norepinephrine uptake
0.51	GO:1903284	positive regulation of glutathione peroxidase activity
0.51	GO:1903285	positive regulation of hydrogen peroxide catabolic process
0.51	GO:1904715	negative regulation of chaperone-mediated autophagy

0.60	GO:1903136	cuprous ion binding
0.50	GO:0005509	calcium ion binding
0.50	GO:0048156	tau protein binding
0.49	GO:0050544	arachidonic acid binding
0.49	GO:0043014	alpha-tubulin binding
0.48	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.48	GO:0030544	Hsp70 protein binding
0.48	GO:0019894	kinesin binding
0.47	GO:0070840	dynein complex binding
0.47	GO:0051219	phosphoprotein binding

0.57	GO:0016234	inclusion body
0.54	GO:0045202	synapse
0.50	GO:0031092	platelet alpha granule membrane
0.48	GO:0030426	growth cone
0.47	GO:0043025	neuronal cell body
0.46	GO:0030424	axon
0.46	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0005739	mitochondrion
0.45	GO:0005615	extracellular space
0.45	GO:0005829	cytosol

0.38

GO:0016491

tr|Q7SX94|Q7SX94_DANRE
Prefoldin subunit 6
Search

PFDN6

0.93	HLA class II region expressed gene KE2

0.69	GO:0006457	protein folding
0.55	GO:0051131	chaperone-mediated protein complex assembly
0.41	GO:0043622	cortical microtubule organization
0.33	GO:0034765	regulation of ion transmembrane transport
0.33	GO:0071805	potassium ion transmembrane transport
0.30	GO:0008152	metabolic process

0.71	GO:0051082	unfolded protein binding
0.52	GO:0051087	chaperone binding
0.33	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.33	GO:0005249	voltage-gated potassium channel activity
0.33	GO:0005509	calcium ion binding

0.80	GO:0016272	prefoldin complex
0.38	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.33	EC:3.2.1.113	GO:0004571
0.33	KEGG:R05982 KEGG:R06722	GO:0004571

sp|Q7SX95|MAD3_DANRE
Max dimerization protein 3
Search

MXD3

0.90	Max dimerization protein 3

0.48	GO:0000122	negative regulation of transcription by RNA polymerase II
0.37	GO:0006351	transcription, DNA-templated
0.34	GO:0008285	negative regulation of cell proliferation

0.67	GO:0046983	protein dimerization activity
0.50	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.48	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.37	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0000987	proximal promoter sequence-specific DNA binding
0.34	GO:0003714	transcription corepressor activity

0.46	GO:0090575	RNA polymerase II transcription factor complex
0.36	GO:0000790	nuclear chromatin
0.36	GO:0005654	nucleoplasm
0.36	GO:0005829	cytosol
0.34	GO:0005739	mitochondrion

sp|Q7SX99|FUMH_DANRE
Fumarate hydratase, mitochondrial
Search

0.44	Argininosuccinate lyase

0.78	GO:0006106	fumarate metabolic process
0.70	GO:0006099	tricarboxylic acid cycle
0.51	GO:0048873	homeostasis of number of cells within a tissue
0.46	GO:0006108	malate metabolic process
0.34	GO:0022900	electron transport chain
0.34	GO:0007034	vacuolar transport

0.79	GO:0004333	fumarate hydratase activity
0.36	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.35	GO:0050660	flavin adenine dinucleotide binding
0.34	GO:0005515	protein binding

0.77	GO:0045239	tricarboxylic acid cycle enzyme complex
0.45	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.34	GO:0019866	organelle inner membrane
0.33	GO:0031974	membrane-enclosed lumen

0.79	EC:4.2.1.2	GO:0004333
0.79	KEGG:R01082	GO:0004333

tr|Q7SXA1|Q7SXA1_DANRE
Ribosomal protein L26
Search

RPL26

0.84	Ribosomal protein L26

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.55	GO:1902167	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.54	GO:1904803	regulation of translation involved in cellular response to UV
0.54	GO:1902164	positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.54	GO:0010467	gene expression
0.53	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
0.53	GO:0009059	macromolecule biosynthetic process
0.51	GO:0071480	cellular response to gamma radiation
0.51	GO:0042273	ribosomal large subunit biogenesis

0.64	GO:0003735	structural constituent of ribosome
0.49	GO:0048027	mRNA 5'-UTR binding
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding

0.71	GO:0015934	large ribosomal subunit
0.52	GO:0022626	cytosolic ribosome
0.46	GO:0005730	nucleolus
0.45	GO:0005654	nucleoplasm
0.37	GO:0070062	extracellular exosome
0.34	GO:0043195	terminal bouton
0.30	GO:0031224	intrinsic component of membrane

tr|Q7SXA3|Q7SXA3_DANRE
Ribosomal protein S27a
Search

RPS27A

0.66	Epididymis luminal protein 112

0.60	GO:0006518	peptide metabolic process
0.59	GO:0043604	amide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:1901566	organonitrogen compound biosynthetic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.36	GO:0006301	postreplication repair
0.36	GO:0007623	circadian rhythm
0.35	GO:0035635	entry of bacterium into host cell
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition

0.64	GO:0003735	structural constituent of ribosome
0.36	GO:0046872	metal ion binding
0.34	GO:0031386	protein tag
0.33	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.50	GO:0043209	myelin sheath
0.46	GO:0044445	cytosolic part
0.41	GO:0044446	intracellular organelle part
0.37	GO:0005634	nucleus
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0070062	extracellular exosome
0.34	GO:0030139	endocytic vesicle
0.34	GO:0012506	vesicle membrane
0.34	GO:0005768	endosome

sp|Q7SXA9|MUS81_DANRE
Crossover junction endonuclease MUS81
Search

MUS81

0.73	MUS81 structure-specific endonuclease subunit

0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.50	GO:0072429	response to intra-S DNA damage checkpoint signaling
0.49	GO:0000712	resolution of meiotic recombination intermediates
0.49	GO:0031573	intra-S DNA damage checkpoint
0.48	GO:0044818	mitotic G2/M transition checkpoint
0.48	GO:0031572	G2 DNA damage checkpoint
0.47	GO:0000727	double-strand break repair via break-induced replication
0.47	GO:0031297	replication fork processing
0.46	GO:0006308	DNA catabolic process
0.37	GO:0006468	protein phosphorylation

0.64	GO:0004518	nuclease activity
0.55	GO:0003677	DNA binding
0.43	GO:0140097	catalytic activity, acting on DNA
0.37	GO:0004672	protein kinase activity
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0043168	anion binding
0.35	GO:0008144	drug binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.46	GO:0048476	Holliday junction resolvase complex
0.40	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.64

EC:3.1

GO:0004518

sp|Q7SXB3|P3IP1_DANRE
Phosphoinositide-3-kinase-interacting protein 1
Search

PIK3IP1

0.97	Phosphoinositide-3-kinase-interacting protein 1

0.62	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity
0.59	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling
0.49	GO:0016310	phosphorylation
0.37	GO:0048903	anterior lateral line neuromast hair cell differentiation
0.36	GO:0031639	plasminogen activation
0.36	GO:0048916	posterior lateral line development
0.36	GO:0001889	liver development
0.35	GO:0001525	angiogenesis
0.34	GO:0006898	receptor-mediated endocytosis
0.33	GO:0007166	cell surface receptor signaling pathway

0.60	GO:0036313	phosphatidylinositol 3-kinase catalytic subunit binding
0.51	GO:0016301	kinase activity
0.37	GO:0004252	serine-type endopeptidase activity
0.35	GO:0005044	scavenger receptor activity
0.32	GO:0004888	transmembrane signaling receptor activity
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0030554	adenyl nucleotide binding
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005576	extracellular region
0.36	GO:0005886	plasma membrane
0.35	GO:0031982	vesicle
0.33	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

0.37

GO:0004252

sp|Q7SXB5|PF23B_DANRE
PHD finger protein 23B
Search

0.86	PHD finger protein 23

0.48	GO:1901097	negative regulation of autophagosome maturation
0.47	GO:1902902	negative regulation of autophagosome assembly
0.47	GO:0007076	mitotic chromosome condensation
0.45	GO:0031398	positive regulation of protein ubiquitination
0.41	GO:0006914	autophagy

0.53	GO:0046872	metal ion binding
0.45	GO:0003682	chromatin binding

0.42	GO:0005634	nucleus
0.36	GO:0043233	organelle lumen
0.35	GO:0005737	cytoplasm
0.35	GO:0044446	intracellular organelle part

sp|Q7SXB7|MFD4A_DANRE
Major facilitator superfamily domain-containing protein 4A
Search

MFSD4A

0.96	LOW QUALITY PROTEIN: major facilitator superfamily domain-containing protein 4

0.48	GO:0055085	transmembrane transport
0.48	GO:0015758	glucose transport

0.48

GO:0005355

glucose transmembrane transporter activity

0.30

GO:0044425

membrane part

sp|Q7SXC6|SLAIL_DANRE
SLAIN motif-containing protein-like
Search

0.86	SLAIN motif-containing protein 2

0.40

GO:0005515

protein binding

0.47	GO:0005856	cytoskeleton
0.38	GO:0005737	cytoplasm

tr|Q7SXD1|Q7SXD1_DANRE
TraB domain containing
Search

TRABD

0.92	TraB domain-containing

0.48

GO:0006811

ion transport

0.65	GO:0005921	gap junction
0.46	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q7SXE4|GOGA5_DANRE
Golgin subfamily A member 5
Search

GOLGA5

0.94	Golgi autoantigen, golgin subfamily a, 5

0.80	GO:0007030	Golgi organization
0.51	GO:0048193	Golgi vesicle transport

0.51	GO:0017137	Rab GTPase binding
0.50	GO:0042803	protein homodimerization activity
0.34	GO:0030674	protein binding, bridging

0.52	GO:0031985	Golgi cisterna
0.52	GO:0005801	cis-Golgi network
0.50	GO:0000139	Golgi membrane
0.35	GO:0031410	cytoplasmic vesicle
0.34	GO:0012506	vesicle membrane
0.34	GO:0098805	whole membrane
0.30	GO:0044425	membrane part

tr|Q7SXE9|Q7SXE9_DANRE
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11
Search

NDUFA11

0.41	NADH dehydrogenase

0.45	GO:0032981	mitochondrial respiratory chain complex I assembly
0.37	GO:0055114	oxidation-reduction process
0.34	GO:0006119	oxidative phosphorylation
0.33	GO:0055085	transmembrane transport

0.36	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.33	GO:0022857	transmembrane transporter activity

0.53	GO:0005747	mitochondrial respiratory chain complex I
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0008137

sp|Q7SXF1|DHCR7_DANRE
7-dehydrocholesterol reductase
Search

DHCR7

0.93	7-dehydrocholesterol reductase large variant

0.57	GO:0006695	cholesterol biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.50	GO:0035264	multicellular organism growth
0.50	GO:0016132	brassinosteroid biosynthetic process
0.50	GO:0030324	lung development
0.48	GO:0001568	blood vessel development
0.48	GO:0009791	post-embryonic development
0.47	GO:0042127	regulation of cell proliferation
0.45	GO:0030154	cell differentiation
0.40	GO:0045540	regulation of cholesterol biosynthetic process

0.73	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
0.51	GO:0009918	sterol delta7 reductase activity
0.39	GO:0050661	NADP binding

0.54	GO:0005640	nuclear outer membrane
0.50	GO:0005783	endoplasmic reticulum
0.46	GO:0005829	cytosol
0.43	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.73

EC:1.3.1

GO:0016628

sp|Q7SXF2|UBL5_DANRE
Ubiquitin-like protein 5
Search

UBL5

0.90	Ubiquitin protein 5

0.67	GO:1903955	positive regulation of protein targeting to mitochondrion
0.62	GO:0034126	positive regulation of MyD88-dependent toll-like receptor signaling pathway
0.60	GO:0000398	mRNA splicing, via spliceosome
0.50	GO:0036211	protein modification process
0.47	GO:0044267	cellular protein metabolic process
0.39	GO:0000753	cell morphogenesis involved in conjugation with cellular fusion

0.66	GO:0031386	protein tag
0.38	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.35	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding

0.50	GO:0005634	nucleus
0.46	GO:0005737	cytoplasm
0.38	GO:0005937	mating projection

0.38

GO:0003755

sp|Q7SXF6|CREL2_DANRE
Cysteine-rich with EGF-like domain protein 2
Search

CRELD2

0.78	Cysteine rich with EGF like domains 2

0.34

GO:0006468

protein phosphorylation

0.69	GO:0005509	calcium ion binding
0.34	GO:0004672	protein kinase activity
0.33	GO:0005515	protein binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005615	extracellular space
0.49	GO:0005783	endoplasmic reticulum
0.48	GO:0005794	Golgi apparatus
0.30	GO:0044425	membrane part

sp|Q7SXG4|SAE2_DANRE
SUMO-activating enzyme subunit 2
Search

UBA2

0.93	Ubiquitin like modifier activating enzyme 2

0.81	GO:0016925	protein sumoylation
0.34	GO:0043085	positive regulation of catalytic activity

0.85	GO:0019948	SUMO activating enzyme activity
0.71	GO:0016881	acid-amino acid ligase activity
0.56	GO:0044388	small protein activating enzyme binding
0.54	GO:0032183	SUMO binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0044390	ubiquitin-like protein conjugating enzyme binding
0.53	GO:0046872	metal ion binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0046982	protein heterodimerization activity

0.57	GO:0031510	SUMO activating enzyme complex
0.46	GO:0005654	nucleoplasm
0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.71

EC:6.3.2

GO:0016881

tr|Q7SXH5|Q7SXH5_DANRE
Ubiquitin-conjugating enzyme E2D 1a
Search

0.92	Ubiquitin-conjugating enzyme E2 D4

0.58	GO:0070936	protein K48-linked ubiquitination
0.54	GO:1902916	positive regulation of protein polyubiquitination
0.48	GO:0035519	protein K29-linked ubiquitination
0.48	GO:0044314	protein K27-linked ubiquitination
0.48	GO:0085020	protein K6-linked ubiquitination
0.47	GO:0006511	ubiquitin-dependent protein catabolic process
0.47	GO:0070979	protein K11-linked ubiquitination
0.47	GO:0070534	protein K63-linked ubiquitination
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0035666	TRIF-dependent toll-like receptor signaling pathway

0.58	GO:0061631	ubiquitin conjugating enzyme activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0016874	ligase activity

0.48	GO:0000151	ubiquitin ligase complex
0.42	GO:0043234	protein complex
0.37	GO:0005737	cytoplasm
0.33	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.33

GO:0004222

tr|Q7SXI1|Q7SXI1_DANRE
Cox7a2l protein
Search

0.97	Cytochrome c oxidase subunit VIIa polypeptide 2 like

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.36	GO:0097250	mitochondrial respiratory chain supercomplex assembly
0.35	GO:0002082	regulation of oxidative phosphorylation
0.33	GO:0006119	oxidative phosphorylation
0.33	GO:0009060	aerobic respiration

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.79	GO:0005746	mitochondrial respiratory chain
0.47	GO:0005730	nucleolus
0.36	GO:0097249	mitochondrial respiratory chain supercomplex
0.30	GO:0016021	integral component of membrane

0.65

GO:0016676

tr|Q7SXI4|Q7SXI4_DANRE
Zinc finger, AN1-type domain 2A
Search

ZFAND2B

0.92	Zinc finger AN1-type containing 2B

0.53	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation
0.39	GO:0071243	cellular response to arsenic-containing substance
0.38	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process

0.62	GO:0008270	zinc ion binding
0.34	GO:0005515	protein binding

0.36	GO:0005622	intracellular
0.36	GO:1905369	endopeptidase complex
0.35	GO:0012505	endomembrane system
0.34	GO:0043234	protein complex
0.34	GO:0043227	membrane-bounded organelle

sp|Q7SXI6|NDL1A_DANRE
Nuclear distribution protein nudE-like 1-A
Search

NDEL1

0.93	NudE neurodevelopment protein 1 like 1

0.86	GO:0060052	neurofilament cytoskeleton organization
0.86	GO:0007100	mitotic centrosome separation
0.85	GO:2000574	regulation of microtubule motor activity
0.74	GO:0007399	nervous system development
0.55	GO:1900029	positive regulation of ruffle assembly
0.54	GO:0051642	centrosome localization
0.54	GO:0047496	vesicle transport along microtubule
0.53	GO:0032418	lysosome localization
0.52	GO:0008090	retrograde axonal transport
0.51	GO:0001833	inner cell mass cell proliferation

0.51	GO:0043014	alpha-tubulin binding
0.50	GO:0048487	beta-tubulin binding
0.49	GO:0008017	microtubule binding
0.47	GO:0042802	identical protein binding
0.39	GO:0070012	oligopeptidase activity
0.36	GO:0032403	protein complex binding
0.34	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.53	GO:0060053	neurofilament cytoskeleton
0.52	GO:0043203	axon hillock
0.52	GO:0000776	kinetochore
0.50	GO:1904115	axon cytoplasm
0.50	GO:0005813	centrosome
0.50	GO:0005875	microtubule associated complex
0.49	GO:0008021	synaptic vesicle
0.48	GO:0031252	cell leading edge
0.42	GO:0005819	spindle
0.41	GO:0005874	microtubule

0.34

EC:2.7.10.1

GO:0004714

sp|Q7SXK5|HUTI_DANRE
Probable imidazolonepropionase
Search

AMDHD1

0.96	Amidohydrolase domain containing 1

0.78	GO:0043606	formamide metabolic process
0.78	GO:0006548	histidine catabolic process
0.74	GO:0006536	glutamate metabolic process
0.39	GO:0015942	formate metabolic process
0.37	GO:0000387	spliceosomal snRNP assembly

0.75	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
0.35	GO:0046872	metal ion binding

0.49	GO:0005737	cytoplasm
0.36	GO:0005681	spliceosomal complex

0.75

EC:3.5.2

GO:0016812

sp|Q7SXL3|TBP_DANRE
TATA-box-binding protein
Search

TBP

0.62	TATA-binding protein 1

0.69	GO:0006352	DNA-templated transcription, initiation
0.53	GO:0006366	transcription by RNA polymerase II
0.52	GO:0006359	regulation of transcription by RNA polymerase III
0.51	GO:0006383	transcription by RNA polymerase III
0.46	GO:0065004	protein-DNA complex assembly
0.45	GO:0007369	gastrulation
0.43	GO:0006402	mRNA catabolic process
0.38	GO:0009792	embryo development ending in birth or egg hatching
0.37	GO:0007283	spermatogenesis
0.36	GO:0045893	positive regulation of transcription, DNA-templated

0.56	GO:0001034	RNA polymerase III transcription factor activity, sequence-specific DNA binding
0.55	GO:0003677	DNA binding
0.52	GO:0001093	TFIIB-class transcription factor binding
0.51	GO:0017162	aryl hydrocarbon receptor binding
0.50	GO:0001129	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly
0.50	GO:0001103	RNA polymerase II repressing transcription factor binding
0.46	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0019899	enzyme binding

0.51	GO:0001940	male pronucleus
0.51	GO:0001939	female pronucleus
0.51	GO:0005669	transcription factor TFIID complex
0.50	GO:0097550	transcriptional preinitiation complex
0.49	GO:0005719	nuclear euchromatin
0.48	GO:0005672	transcription factor TFIIA complex
0.37	GO:0005737	cytoplasm
0.35	GO:0000120	RNA polymerase I transcription factor complex

sp|Q7SXL7|FL2D_DANRE
Pre-mRNA-splicing regulator WTAP
Search

WTAP

0.95	Pre-mRNA-splicing regulator WTAP

0.84	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.80	GO:0080009	mRNA methylation
0.43	GO:0042981	regulation of apoptotic process
0.38	GO:0008380	RNA splicing
0.37	GO:0006397	mRNA processing
0.37	GO:0007049	cell cycle
0.34	GO:0000226	microtubule cytoskeleton organization
0.33	GO:0007275	multicellular organism development

0.35	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.55	GO:0036396	RNA N6-methyladenosine methyltransferase complex
0.46	GO:0031974	membrane-enclosed lumen
0.45	GO:0012505	endomembrane system
0.43	GO:0031967	organelle envelope
0.43	GO:0031090	organelle membrane
0.33	GO:0015630	microtubule cytoskeleton
0.30	GO:0016021	integral component of membrane

0.35

GO:0016747

sp|Q7SXM0|HDAC8_DANRE
Histone deacetylase 8
Search

HDAC8

0.51	Histone deacetylase

0.78	GO:0016575	histone deacetylation
0.59	GO:0071922	regulation of cohesin loading
0.55	GO:0031397	negative regulation of protein ubiquitination
0.55	GO:0032204	regulation of telomere maintenance
0.52	GO:0031647	regulation of protein stability
0.52	GO:0007062	sister chromatid cohesion
0.50	GO:0006351	transcription, DNA-templated
0.49	GO:1903506	regulation of nucleic acid-templated transcription
0.49	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.49	GO:0010468	regulation of gene expression

0.79	GO:0004407	histone deacetylase activity
0.66	GO:0034979	NAD-dependent protein deacetylase activity
0.56	GO:0051879	Hsp90 protein binding
0.56	GO:0030544	Hsp70 protein binding
0.52	GO:0046872	metal ion binding
0.37	GO:0003682	chromatin binding
0.36	GO:0008134	transcription factor binding

0.54	GO:0005634	nucleus
0.42	GO:0005886	plasma membrane
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0005737	cytoplasm
0.34	GO:1902494	catalytic complex
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome
0.30	GO:0016021	integral component of membrane

0.79

GO:0004407

tr|Q7SXM1|Q7SXM1_DANRE
Cytochrome c oxidase subunit
Search

0.74	Cytochrome c oxidase subunit

0.49	GO:0033617	mitochondrial respiratory chain complex IV assembly
0.42	GO:1902600	hydrogen ion transmembrane transport
0.41	GO:0022900	electron transport chain
0.35	GO:0021762	substantia nigra development
0.34	GO:0034968	histone lysine methylation
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression
0.33	GO:0006119	oxidative phosphorylation
0.33	GO:0009060	aerobic respiration

0.43	GO:0015002	heme-copper terminal oxidase activity
0.43	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.42	GO:0015078	hydrogen ion transmembrane transporter activity
0.41	GO:0009055	electron transfer activity
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0018024	histone-lysine N-methyltransferase activity
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0008270	zinc ion binding

0.61	GO:0005739	mitochondrion
0.49	GO:0031970	organelle envelope lumen
0.46	GO:0045277	respiratory chain complex IV
0.45	GO:0019866	organelle inner membrane
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.43

GO:0016676

sp|Q7SXM7|PRP31_DANRE
U4/U6 small nuclear ribonucleoprotein Prp31
Search

PRPF31

0.93	Pre-mRNA processing factor 31

0.85	GO:0000244	spliceosomal tri-snRNP complex assembly
0.60	GO:0071166	ribonucleoprotein complex localization
0.54	GO:0060041	retina development in camera-type eye
0.39	GO:0048254	snoRNA localization

0.69	GO:0030622	U4atac snRNA binding
0.69	GO:0070990	snRNP binding
0.67	GO:0030621	U4 snRNA binding

0.81	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.68	GO:0005687	U4 snRNP
0.64	GO:0015030	Cajal body
0.62	GO:0071339	MLL1 complex
0.61	GO:0016607	nuclear speck
0.57	GO:0005690	U4atac snRNP
0.54	GO:0071011	precatalytic spliceosome
0.38	GO:0019013	viral nucleocapsid
0.30	GO:0031224	intrinsic component of membrane

tr|Q7SXN2|Q7SXN2_DANRE
Heterogeneous nuclear ribonucleoprotein D-like
Search

HNRNPDL

0.93	Heterogeneous nuclear ribonucleoprotein D like

0.41	GO:1905663	positive regulation of telomerase RNA reverse transcriptase activity
0.41	GO:0097167	circadian regulation of translation
0.40	GO:1904355	positive regulation of telomere capping
0.39	GO:0043488	regulation of mRNA stability
0.39	GO:0042752	regulation of circadian rhythm
0.38	GO:0045727	positive regulation of translation
0.37	GO:0006351	transcription, DNA-templated
0.36	GO:2001141	regulation of RNA biosynthetic process
0.36	GO:0035722	interleukin-12-mediated signaling pathway
0.34	GO:0016071	mRNA metabolic process

0.57	GO:0003723	RNA binding
0.39	GO:0042162	telomeric DNA binding
0.37	GO:0003697	single-stranded DNA binding
0.37	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.62	GO:0019013	viral nucleocapsid
0.55	GO:0030529	intracellular ribonucleoprotein complex
0.48	GO:0005654	nucleoplasm
0.37	GO:0070062	extracellular exosome
0.35	GO:0005737	cytoplasm

sp|Q7SXN4|CPEB4_DANRE
Cytoplasmic polyadenylation element-binding protein 4
Search

CPEB4

0.93	Cytoplasmatic polyadenylation element binding protein 4

0.72	GO:0006417	regulation of translation
0.52	GO:0002931	response to ischemia
0.51	GO:0071230	cellular response to amino acid stimulus
0.42	GO:0034249	negative regulation of cellular amide metabolic process
0.40	GO:0032269	negative regulation of cellular protein metabolic process
0.40	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.40	GO:0042149	cellular response to glucose starvation
0.40	GO:0036294	cellular response to decreased oxygen levels
0.40	GO:0043524	negative regulation of neuron apoptotic process
0.39	GO:0010629	negative regulation of gene expression

0.83	GO:0003730	mRNA 3'-UTR binding
0.83	GO:0045182	translation regulator activity
0.41	GO:0043022	ribosome binding
0.40	GO:0008135	translation factor activity, RNA binding
0.33	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.50	GO:0014069	postsynaptic density
0.49	GO:0030425	dendrite
0.45	GO:0005783	endoplasmic reticulum
0.45	GO:1990124	messenger ribonucleoprotein complex
0.42	GO:0005634	nucleus
0.39	GO:0044309	neuron spine
0.39	GO:0030426	growth cone
0.38	GO:0030424	axon
0.38	GO:0045211	postsynaptic membrane
0.38	GO:0048471	perinuclear region of cytoplasm

sp|Q7SXN5|DNM1L_DANRE
Dynamin-1-like protein
Search

DNM1L

0.85	Dynamin 1 like

0.84	GO:0000266	mitochondrial fission
0.83	GO:0016559	peroxisome fission
0.48	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission
0.47	GO:0070266	necroptotic process
0.46	GO:1900063	regulation of peroxisome organization
0.46	GO:0043653	mitochondrial fragmentation involved in apoptotic process
0.45	GO:0001836	release of cytochrome c from mitochondria
0.45	GO:0090141	positive regulation of mitochondrial fission
0.45	GO:0090200	positive regulation of release of cytochrome c from mitochondria
0.45	GO:0070584	mitochondrion morphogenesis

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.45	GO:0030742	GTP-dependent protein binding
0.44	GO:0042803	protein homodimerization activity
0.43	GO:0017137	Rab GTPase binding
0.43	GO:0031625	ubiquitin protein ligase binding
0.41	GO:0008017	microtubule binding
0.37	GO:0051433	BH2 domain binding
0.36	GO:0008289	lipid binding
0.35	GO:0030276	clathrin binding

0.46	GO:0099073	mitochondrion-derived vesicle
0.43	GO:0005903	brush border
0.43	GO:0005741	mitochondrial outer membrane
0.43	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0005777	peroxisome
0.42	GO:0005829	cytosol
0.41	GO:0005794	Golgi apparatus
0.41	GO:0005874	microtubule
0.40	GO:0005783	endoplasmic reticulum
0.38	GO:0030672	synaptic vesicle membrane

tr|Q7SXN6|Q7SXN6_DANRE
Proteasome subunit alpha type
Search

PSMA6

0.51	Proteasome subunit alpha type

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.68	GO:0043632	modification-dependent macromolecule catabolic process
0.50	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.40	GO:0071346	cellular response to interferon-gamma
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation

0.77	GO:0004298	threonine-type endopeptidase activity
0.52	GO:0051059	NF-kappaB binding
0.41	GO:0003723	RNA binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.58	GO:0005634	nucleus
0.50	GO:0005844	polysome
0.49	GO:0000932	P-body
0.45	GO:0070013	intracellular organelle lumen
0.41	GO:0044446	intracellular organelle part
0.37	GO:0030017	sarcomere
0.36	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.77

GO:0004298

sp|Q7SXP0|S22BB_DANRE
Vesicle-trafficking protein SEC22b-B
Search

SEC22B

0.93	SEC22 homolog B, vesicle trafficking protein b

0.67	GO:0016192	vesicle-mediated transport
0.55	GO:1902902	negative regulation of autophagosome assembly
0.51	GO:0045732	positive regulation of protein catabolic process
0.47	GO:0090174	organelle membrane fusion
0.46	GO:0016050	vesicle organization
0.43	GO:0032940	secretion by cell
0.43	GO:0046907	intracellular transport
0.38	GO:0015031	protein transport
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.34	GO:0051650	establishment of vesicle localization

0.47	GO:0000149	SNARE binding
0.47	GO:0005484	SNAP receptor activity

0.54	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.51	GO:0012507	ER to Golgi transport vesicle membrane
0.48	GO:0005789	endoplasmic reticulum membrane
0.48	GO:0005794	Golgi apparatus
0.47	GO:0031201	SNARE complex
0.43	GO:0042470	melanosome
0.35	GO:0030670	phagocytic vesicle membrane
0.34	GO:0070382	exocytic vesicle
0.30	GO:0016021	integral component of membrane

sp|Q7SXP2|ULA1_DANRE
NEDD8-activating enzyme E1 regulatory subunit
Search

NAE1

0.73	NEDD8-activating enzyme E1 regulatory subunit

0.82	GO:0045116	protein neddylation
0.53	GO:0051402	neuron apoptotic process
0.53	GO:0033314	mitotic DNA replication checkpoint
0.52	GO:0043523	regulation of neuron apoptotic process
0.34	GO:0043687	post-translational protein modification
0.33	GO:0007018	microtubule-based movement
0.33	GO:0007165	signal transduction

0.83	GO:0019781	NEDD8 activating enzyme activity
0.50	GO:0031625	ubiquitin protein ligase binding
0.48	GO:0046982	protein heterodimerization activity
0.33	GO:0003777	microtubule motor activity

0.36	GO:0005737	cytoplasm
0.34	GO:0005886	plasma membrane
0.34	GO:0005868	cytoplasmic dynein complex
0.30	GO:0016021	integral component of membrane

sp|Q7SXP4|SRS1A_DANRE
Serine/arginine-rich splicing factor 1A
Search

SRSF1

0.94	Serine and arginine rich splicing factor 1

0.52	GO:0000395	mRNA 5'-splice site recognition
0.52	GO:0000380	alternative mRNA splicing, via spliceosome
0.51	GO:0060048	cardiac muscle contraction
0.48	GO:0001701	in utero embryonic development
0.39	GO:0097421	liver regeneration
0.38	GO:0033120	positive regulation of RNA splicing
0.38	GO:0048709	oligodendrocyte differentiation
0.38	GO:0051028	mRNA transport
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus

0.59	GO:0003723	RNA binding
0.54	GO:0050733	RS domain binding
0.54	GO:0044547	DNA topoisomerase binding
0.39	GO:0043422	protein kinase B binding

0.51	GO:0016607	nuclear speck
0.51	GO:0035145	exon-exon junction complex
0.50	GO:0071013	catalytic step 2 spliceosome
0.36	GO:0070062	extracellular exosome
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q7SXP8|GMPAB_DANRE
Mannose-1-phosphate guanyltransferase alpha-B
Search

GMPPA

0.84	GDP-mannose pyrophosphorylase Ab

0.49

GO:0009058

biosynthetic process

0.63

GO:0016779

nucleotidyltransferase activity

0.63

EC:2.7.7

GO:0016779

sp|Q7SXR1|TRBP2_DANRE
RISC-loading complex subunit tarbp2
Search

TARBP2

0.97	RISC-loading complex subunit tarbp2

0.85	GO:0035280	miRNA loading onto RISC involved in gene silencing by miRNA
0.85	GO:0031054	pre-miRNA processing
0.84	GO:0030422	production of siRNA involved in RNA interference
0.81	GO:0030423	targeting of mRNA for destruction involved in RNA interference
0.78	GO:0046782	regulation of viral transcription
0.58	GO:0050689	negative regulation of defense response to virus by host
0.56	GO:0035087	siRNA loading onto RISC involved in RNA interference
0.55	GO:0045070	positive regulation of viral genome replication
0.53	GO:0035264	multicellular organism growth
0.53	GO:0007338	single fertilization

0.85	GO:0035197	siRNA binding
0.78	GO:0035198	miRNA binding
0.74	GO:0003725	double-stranded RNA binding
0.68	GO:0042803	protein homodimerization activity
0.54	GO:0047485	protein N-terminus binding
0.53	GO:0070883	pre-miRNA binding
0.48	GO:0019899	enzyme binding
0.35	GO:0036002	pre-mRNA binding

0.82	GO:0016442	RISC complex
0.60	GO:0048471	perinuclear region of cytoplasm
0.59	GO:0070578	RISC-loading complex
0.58	GO:0035068	micro-ribonucleoprotein complex
0.51	GO:0016604	nuclear body
0.33	GO:0005829	cytosol

tr|Q7SXR2|Q7SXR2_DANRE
DnaJ (Hsp40) homolog, subfamily B, member 12
Search

DNAJB12

0.86	LOW QUALITY PROTEIN: dnaJ homolog subfamily B member 12

0.40	GO:0051085	chaperone cofactor-dependent protein refolding
0.39	GO:0071218	cellular response to misfolded protein
0.39	GO:0036503	ERAD pathway
0.38	GO:0043623	cellular protein complex assembly
0.34	GO:0032259	methylation

0.38	GO:0030544	Hsp70 protein binding
0.34	GO:0008168	methyltransferase activity
0.33	GO:0003676	nucleic acid binding

0.38	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0031965	nuclear membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0008168

sp|Q7SXR3|MAEA_DANRE
Macrophage erythroblast attacher
Search

MAEA

0.91	Macrophage erythroblast attacher

0.85	GO:0045721	negative regulation of gluconeogenesis
0.55	GO:0048821	erythrocyte development
0.54	GO:0043353	enucleate erythrocyte differentiation
0.54	GO:0033033	negative regulation of myeloid cell apoptotic process
0.48	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.47	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.47	GO:0007155	cell adhesion
0.46	GO:0007010	cytoskeleton organization
0.46	GO:0071695	anatomical structure maturation
0.45	GO:0048469	cell maturation

0.50	GO:0003779	actin binding
0.45	GO:0004842	ubiquitin-protein transferase activity

0.55	GO:0016363	nuclear matrix
0.52	GO:0005826	actomyosin contractile ring
0.51	GO:0034657	GID complex
0.49	GO:0005819	spindle
0.47	GO:0005654	nucleoplasm
0.45	GO:0005887	integral component of plasma membrane

0.45

GO:0004842

tr|Q7SXR6|Q7SXR6_DANRE
Secretory carrier-associated membrane protein
Search

SCAMP2

0.68	Secretory carrier-associated membrane protein 2

0.65	GO:0015031	protein transport
0.35	GO:0016192	vesicle-mediated transport
0.35	GO:0098657	import into cell
0.34	GO:0046907	intracellular transport
0.34	GO:0034613	cellular protein localization

0.35	GO:0008565	protein transporter activity
0.35	GO:0005515	protein binding

0.55	GO:0032588	trans-Golgi network membrane
0.55	GO:0055038	recycling endosome membrane
0.39	GO:0030133	transport vesicle
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q7SXS7|SETD3_DANRE
Histone-lysine N-methyltransferase setd3
Search

SETD3

0.52	Histone-lysine N-methyltransferase

0.85	GO:0010452	histone H3-K36 methylation
0.85	GO:0018027	peptidyl-lysine dimethylation
0.85	GO:0018026	peptidyl-lysine monomethylation
0.85	GO:0018023	peptidyl-lysine trimethylation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0051568	histone H3-K4 methylation
0.55	GO:0051149	positive regulation of muscle cell differentiation
0.53	GO:1902680	positive regulation of RNA biosynthetic process
0.52	GO:0010628	positive regulation of gene expression
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.85	GO:0046975	histone methyltransferase activity (H3-K36 specific)
0.79	GO:0003713	transcription coactivator activity
0.57	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.55	GO:0001102	RNA polymerase II activating transcription factor binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0000790	nuclear chromatin
0.34	GO:0005654	nucleoplasm

sp|Q7SXS8|HPF1_DANRE
Histone PARylation factor 1
Search

HPF1

0.97	Histone PARylation factor 1

0.87	GO:0018312	peptidyl-serine ADP-ribosylation
0.87	GO:0010835	regulation of protein ADP-ribosylation
0.65	GO:0006974	cellular response to DNA damage stimulus

0.79

GO:0042393

histone binding

0.60

GO:0005634

nucleus

tr|Q7SXT1|Q7SXT1_DANRE
Tartrate-resistant acid phosphatase type 5
Search

ACP5

0.95	Tartrate-resistant acid phosphatase type 5

0.66	GO:0016311	dephosphorylation
0.50	GO:0032929	negative regulation of superoxide anion generation
0.50	GO:0045019	negative regulation of nitric oxide biosynthetic process
0.49	GO:0032691	negative regulation of interleukin-1 beta production
0.49	GO:0032695	negative regulation of interleukin-12 production
0.49	GO:0045453	bone resorption
0.48	GO:0032720	negative regulation of tumor necrosis factor production
0.48	GO:0060349	bone morphogenesis
0.48	GO:0050728	negative regulation of inflammatory response
0.48	GO:0050830	defense response to Gram-positive bacterium

0.75	GO:0003993	acid phosphatase activity
0.51	GO:0008198	ferrous iron binding
0.50	GO:0008199	ferric iron binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003723	RNA binding
0.32	GO:0003677	DNA binding
0.32	GO:0004602	glutathione peroxidase activity

0.46	GO:0005764	lysosome
0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.75

EC:3.1.3.2

GO:0003993

tr|Q7SXT2|Q7SXT2_DANRE
Tetraspanin
Search

TSPAN7

0.59	Tetraspanin

0.44	GO:0007166	cell surface receptor signaling pathway
0.33	GO:0016032	viral process
0.32	GO:0006520	cellular amino acid metabolic process

0.34	GO:0005509	calcium ion binding
0.33	GO:0016743	carboxyl- or carbamoyltransferase activity
0.33	GO:0016597	amino acid binding

0.42	GO:0005887	integral component of plasma membrane
0.34	GO:0005576	extracellular region

0.33

EC:2.1.3

GO:0016743

tr|Q7SXT6|Q7SXT6_DANRE
Musashi RNA-binding protein 2b
Search

0.90	RNA-binding protein Musashi

0.43	GO:0021772	olfactory bulb development
0.38	GO:0048864	stem cell development

0.59

GO:0003723

RNA binding

0.38	GO:0019013	viral nucleocapsid
0.38	GO:0005844	polysome
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q7SXT7|ZC21A_DANRE
Zinc finger C2HC domain-containing protein 1A
Search

ZC2HC1A

0.97	Zinc finger C2HC domain-containing protein 1A isoform B

0.40	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.40	GO:0006099	tricarboxylic acid cycle
0.38	GO:0006886	intracellular protein transport
0.38	GO:0016192	vesicle-mediated transport
0.38	GO:0022900	electron transport chain

0.52	GO:0046872	metal ion binding
0.42	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.42	GO:0005515	protein binding
0.41	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.39	GO:0050660	flavin adenine dinucleotide binding

0.39	GO:0030117	membrane coat
0.37	GO:0031966	mitochondrial membrane
0.37	GO:0019866	organelle inner membrane

0.42	EC:1.3.5.1	GO:0008177
0.42	KEGG:R02164	GO:0008177

sp|Q7SXU0|EI3JA_DANRE
Eukaryotic translation initiation factor 3 subunit J-A
Search

EIF3J

0.73	Eukaryotic translation initiation factor 3 subunit J-A

0.71	GO:0006413	translational initiation
0.68	GO:0002181	cytoplasmic translation
0.67	GO:0006446	regulation of translational initiation
0.64	GO:0022618	ribonucleoprotein complex assembly
0.34	GO:0016311	dephosphorylation
0.33	GO:1903507	negative regulation of nucleic acid-templated transcription

0.72	GO:0003743	translation initiation factor activity
0.34	GO:0016791	phosphatase activity
0.34	GO:0003714	transcription corepressor activity
0.33	GO:0005515	protein binding

0.77	GO:0005852	eukaryotic translation initiation factor 3 complex
0.68	GO:0016282	eukaryotic 43S preinitiation complex
0.68	GO:0033290	eukaryotic 48S preinitiation complex
0.45	GO:0005829	cytosol

0.34

EC:3.1.3 EC:3.1.3.41

GO:0016791

tr|Q7SXU7|Q7SXU7_DANRE
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
Search

DDX39B

0.86	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B

0.77	GO:0046784	viral mRNA export from host cell nucleus
0.76	GO:2000002	negative regulation of DNA damage checkpoint
0.73	GO:0010501	RNA secondary structure unwinding
0.71	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.70	GO:0000245	spliceosomal complex assembly
0.69	GO:0032786	positive regulation of DNA-templated transcription, elongation
0.68	GO:0051028	mRNA transport
0.67	GO:0006405	RNA export from nucleus
0.43	GO:0006974	cellular response to DNA damage stimulus

0.77	GO:0043008	ATP-dependent protein binding
0.76	GO:0030621	U4 snRNA binding
0.73	GO:0017070	U6 snRNA binding
0.69	GO:0004004	ATP-dependent RNA helicase activity
0.63	GO:0042802	identical protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.75	GO:0005687	U4 snRNP
0.72	GO:0000346	transcription export complex
0.71	GO:0005688	U6 snRNP
0.68	GO:0016607	nuclear speck
0.67	GO:0005681	spliceosomal complex
0.47	GO:0005730	nucleolus
0.45	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q7SXV1|TBC23_DANRE
TBC1 domain family member 23
Search

TBC1D23

0.95	TBC1 domain family member 23 isoform A

0.86	GO:1990403	embryonic brain development
0.81	GO:0032755	positive regulation of interleukin-6 production
0.80	GO:0032680	regulation of tumor necrosis factor production
0.77	GO:0050727	regulation of inflammatory response
0.76	GO:0042147	retrograde transport, endosome to Golgi
0.75	GO:0007420	brain development
0.74	GO:0031175	neuron projection development
0.33	GO:0006807	nitrogen compound metabolic process

0.38

GO:0005515

protein binding

0.79	GO:0071203	WASH complex
0.76	GO:0005802	trans-Golgi network
0.65	GO:0005829	cytosol

sp|Q7SXV2|AEBP2_DANRE
Zinc finger protein AEBP2
Search

AEBP2

0.96	AE binding protein 2

0.52

GO:0000122

negative regulation of transcription by RNA polymerase II

0.55	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0003714	transcription corepressor activity
0.53	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.56

GO:0035098

ESC/E(Z) complex

sp|Q7SXV9|CALUB_DANRE
Calumenin-B
Search

CALU

0.92	Calumenin-B

0.35	GO:0048731	system development
0.35	GO:0048678	response to axon injury
0.34	GO:0031099	regeneration
0.34	GO:0043687	post-translational protein modification
0.34	GO:0001701	in utero embryonic development
0.34	GO:0014070	response to organic cyclic compound
0.34	GO:0120036	plasma membrane bounded cell projection organization
0.34	GO:0048468	cell development
0.33	GO:0043086	negative regulation of catalytic activity
0.33	GO:0033554	cellular response to stress

0.70	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.34	GO:0004857	enzyme inhibitor activity

0.50	GO:0005783	endoplasmic reticulum
0.45	GO:0042470	melanosome
0.45	GO:0016528	sarcoplasm
0.42	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.42	GO:0005794	Golgi apparatus
0.41	GO:0031984	organelle subcompartment
0.40	GO:0043233	organelle lumen
0.40	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|Q7SXW0|S2539_DANRE
Solute carrier family 25 member 39
Search

0.88	Solute carrier family 25 member 39 isoform A

0.52	GO:0055085	transmembrane transport
0.44	GO:0006839	mitochondrial transport
0.36	GO:0006828	manganese ion transport
0.35	GO:0006783	heme biosynthetic process

0.38	GO:0022857	transmembrane transporter activity
0.36	GO:0016530	metallochaperone activity

0.43	GO:0005739	mitochondrion
0.40	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

tr|Q7SXW1|Q7SXW1_DANRE
Tropomyosin 4b
Search

0.79	Cytoskeletal tropomyosin

0.70	GO:0006936	muscle contraction
0.64	GO:0097435	supramolecular fiber organization
0.64	GO:0030036	actin cytoskeleton organization
0.54	GO:0060047	heart contraction
0.54	GO:0055013	cardiac muscle cell development
0.52	GO:0010927	cellular component assembly involved in morphogenesis
0.47	GO:0070925	organelle assembly
0.41	GO:0033275	actin-myosin filament sliding
0.40	GO:0001649	osteoblast differentiation
0.39	GO:0061515	myeloid cell development

0.69	GO:0008307	structural constituent of muscle
0.63	GO:0051015	actin filament binding
0.46	GO:0042803	protein homodimerization activity
0.45	GO:0046982	protein heterodimerization activity
0.38	GO:0046872	metal ion binding
0.36	GO:0003924	GTPase activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0005884	actin filament
0.72	GO:0005862	muscle thin filament tropomyosin
0.68	GO:0097517	contractile actin filament bundle
0.67	GO:0042641	actomyosin
0.63	GO:0002102	podosome
0.58	GO:0030863	cortical cytoskeleton
0.39	GO:0005925	focal adhesion
0.39	GO:0070062	extracellular exosome
0.37	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q7SXW2|ZGPAT_DANRE
Zinc finger CCCH-type with G patch domain-containing protein
Search

ZGPAT

0.94	Zinc finger CCCH-type and G-patch domain containing

0.57	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity
0.50	GO:0045892	negative regulation of transcription, DNA-templated
0.46	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0006351	transcription, DNA-templated
0.36	GO:0050852	T cell receptor signaling pathway
0.35	GO:0050853	B cell receptor signaling pathway

0.52	GO:0046872	metal ion binding
0.51	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0003676	nucleic acid binding
0.34	GO:0005515	protein binding

0.45	GO:0005634	nucleus
0.40	GO:0005886	plasma membrane

sp|Q7SXW3|LRC40_DANRE
Leucine-rich repeat-containing protein 40
Search

LRRC40

0.89	Leucine-rich repeat-containing protein 40

0.61

GO:0007165

signal transduction

0.56

GO:0005886

plasma membrane

sp|Q7SXW4|EMC3_DANRE
ER membrane protein complex subunit 3
Search

EMC3

0.73	ER membrane protein complex subunit 3

0.49	GO:0034975	protein folding in endoplasmic reticulum
0.45	GO:0045494	photoreceptor cell maintenance
0.44	GO:0060041	retina development in camera-type eye

0.56	GO:0072546	ER membrane protein complex
0.44	GO:0030140	trans-Golgi network transport vesicle
0.41	GO:0005794	Golgi apparatus

sp|Q7SXW6|ARP2A_DANRE
Actin-related protein 2-A
Search

ACTR2

0.85	Actin-related protein 2 isoform a

0.81	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.54	GO:0016344	meiotic chromosome movement towards spindle pole
0.52	GO:0033206	meiotic cytokinesis
0.51	GO:0071346	cellular response to interferon-gamma
0.51	GO:0008356	asymmetric cell division
0.51	GO:0051653	spindle localization
0.50	GO:0060271	cilium assembly
0.49	GO:0016482	cytosolic transport
0.49	GO:0007163	establishment or maintenance of cell polarity
0.40	GO:0035984	cellular response to trichostatin A

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0003779	actin binding
0.49	GO:0005200	structural constituent of cytoskeleton
0.48	GO:0032403	protein complex binding

0.80	GO:0005885	Arp2/3 protein complex
0.53	GO:0030478	actin cap
0.45	GO:0005829	cytosol
0.41	GO:0061825	podosome core
0.40	GO:0042995	cell projection
0.38	GO:0014069	postsynaptic density
0.38	GO:0031252	cell leading edge
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen

tr|Q7SXX4|Q7SXX4_DANRE
Hippocalcin-like 1
Search

HPCAL1

0.83	Hippocalcin-like protein 1

0.69	GO:0005509	calcium ion binding
0.36	GO:0005515	protein binding

0.37	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|Q7SXX7|MB12A_DANRE
Multivesicular body subunit 12A
Search

MVB12A

0.97	Multivesicular body subunit 12A

0.58	GO:0019075	virus maturation
0.56	GO:0042058	regulation of epidermal growth factor receptor signaling pathway
0.54	GO:1903772	regulation of viral budding via host ESCRT complex
0.53	GO:0048524	positive regulation of viral process
0.38	GO:0015031	protein transport
0.36	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
0.35	GO:0036258	multivesicular body assembly
0.35	GO:0016197	endosomal transport
0.35	GO:0075733	intracellular transport of virus
0.34	GO:0016236	macroautophagy

0.50	GO:0043130	ubiquitin binding
0.50	GO:0008289	lipid binding
0.41	GO:0017124	SH3 domain binding
0.34	GO:0015245	fatty acid transmembrane transporter activity
0.34	GO:0031957	very long-chain fatty acid-CoA ligase activity
0.33	GO:0004467	long-chain fatty acid-CoA ligase activity
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003677	DNA binding

0.83	GO:0000813	ESCRT I complex
0.49	GO:0005813	centrosome
0.48	GO:0005829	cytosol
0.47	GO:0005770	late endosome
0.47	GO:0005794	Golgi apparatus
0.46	GO:0005654	nucleoplasm
0.43	GO:0005769	early endosome
0.37	GO:0070062	extracellular exosome
0.37	GO:0005886	plasma membrane
0.35	GO:0000444	MIS12/MIND type complex

0.33

EC:6.2.1.3

GO:0004467

sp|Q7SXY4|DC2L1_DANRE
Cytoplasmic dynein 2 light intermediate chain 1
Search

DYNC2LI1

0.96	Cytoplasmic dynein 2 light intermediate chain 1

0.85	GO:0035735	intraciliary transport involved in cilium assembly
0.81	GO:1902017	regulation of cilium assembly
0.79	GO:0007368	determination of left/right symmetry
0.68	GO:0035721	intraciliary retrograde transport

0.85	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed
0.69	GO:0045504	dynein heavy chain binding

0.82	GO:0005868	cytoplasmic dynein complex
0.82	GO:0036064	ciliary basal body
0.81	GO:0005930	axoneme
0.79	GO:0035869	ciliary transition zone
0.79	GO:0030990	intraciliary transport particle
0.76	GO:0045177	apical part of cell
0.75	GO:0031514	motile cilium
0.74	GO:0005813	centrosome
0.48	GO:0005874	microtubule
0.41	GO:0097730	non-motile cilium

0.85

EC:3.6.4.5

GO:0008569

sp|Q7SXZ1|PIGB_DANRE
GPI mannosyltransferase 3
Search

PIGB

0.58	Mannosyltransferase

0.53	GO:0006506	GPI anchor biosynthetic process
0.53	GO:0097502	mannosylation
0.32	GO:0006281	DNA repair

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0008094	DNA-dependent ATPase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016757

sp|Q7SY06|HACD3_DANRE
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase
Search

HACD3

0.70	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase

0.70	GO:0006633	fatty acid biosynthetic process
0.57	GO:0046726	positive regulation by virus of viral protein levels in host cell
0.56	GO:0000038	very long-chain fatty acid metabolic process
0.55	GO:0045070	positive regulation of viral genome replication
0.54	GO:0007254	JNK cascade
0.54	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.53	GO:0007266	Rho protein signal transduction
0.47	GO:0030148	sphingolipid biosynthetic process
0.35	GO:0016601	Rac protein signal transduction
0.35	GO:0043507	positive regulation of JUN kinase activity

0.85	GO:0102158	very-long-chain 3-hydroxyacyl-CoA dehydratase activity
0.85	GO:0102343	3-hydroxy-arachidoyl-CoA dehydratase activity
0.85	GO:0102345	3-hydroxy-lignoceroyl-CoA dehydratase activity
0.85	GO:0102344	3-hydroxy-behenoyl-CoA dehydratase activity
0.59	GO:0018812	3-hydroxyacyl-CoA dehydratase activity
0.48	GO:0019899	enzyme binding
0.34	GO:0005096	GTPase activator activity

0.72	GO:0005789	endoplasmic reticulum membrane
0.52	GO:0031965	nuclear membrane
0.47	GO:0005829	cytosol
0.44	GO:0005739	mitochondrion
0.36	GO:0005925	focal adhesion
0.30	GO:0016021	integral component of membrane

0.85

EC:4.2.1.134

GO:0102343

sp|Q7SY07|EIF1A_DANRE
Probable RNA-binding protein EIF1AD
Search

EIF1AD

0.96	Eukaryotic translation initiation factor 1A domain containing

0.71	GO:0006413	translational initiation
0.34	GO:0007020	microtubule nucleation

0.72	GO:0003743	translation initiation factor activity
0.34	GO:0043015	gamma-tubulin binding

0.42	GO:0005634	nucleus
0.34	GO:0000922	spindle pole
0.33	GO:0005815	microtubule organizing center

tr|Q7SY08|Q7SY08_DANRE
Transmembrane protein 110
Search

TMEM110

0.61	store-operated calcium entry regulator STIMATE

0.52	GO:0035988	chondrocyte proliferation
0.50	GO:0002062	chondrocyte differentiation
0.50	GO:0042246	tissue regeneration
0.39	GO:0051533	positive regulation of NFAT protein import into nucleus
0.39	GO:0032237	activation of store-operated calcium channel activity
0.39	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.36	GO:1902730	positive regulation of proteoglycan biosynthetic process
0.36	GO:1902732	positive regulation of chondrocyte proliferation
0.35	GO:0032332	positive regulation of chondrocyte differentiation
0.34	GO:0010628	positive regulation of gene expression

0.38	GO:0005246	calcium channel regulator activity
0.33	GO:0005515	protein binding

0.42	GO:0005634	nucleus
0.38	GO:0032541	cortical endoplasmic reticulum
0.36	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

sp|Q7SY09|AGRL4_DANRE
Adhesion G protein-coupled receptor L4
Search

ADGRL4

0.87	EGF, latrophilin and seven transmembrane domain containing 1 precursor

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0060317	cardiac epithelial to mesenchymal transition

0.72	GO:0004930	G-protein coupled receptor activity
0.64	GO:0005509	calcium ion binding
0.49	GO:0030246	carbohydrate binding
0.35	GO:0046983	protein dimerization activity
0.34	GO:0016524	latrotoxin receptor activity

0.35	GO:0031410	cytoplasmic vesicle
0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q7SY10|T161B_DANRE
Transmembrane protein 161B
Search

TMEM161B

0.78	LOW QUALITY PROTEIN: transmembrane protein 161B

0.33

GO:0015074

DNA integration

0.32

GO:0003676

nucleic acid binding

0.30

GO:0031224

intrinsic component of membrane

sp|Q7SY21|TADA3_DANRE
Transcriptional adapter 3
Search

TADA3

0.84	Transcriptional adapter 3-B

0.80	GO:0090043	regulation of tubulin deacetylation
0.78	GO:0043966	histone H3 acetylation
0.77	GO:0031063	regulation of histone deacetylation
0.70	GO:0031647	regulation of protein stability
0.68	GO:0043967	histone H4 acetylation
0.66	GO:0000278	mitotic cell cycle
0.65	GO:0001932	regulation of protein phosphorylation
0.64	GO:0045893	positive regulation of transcription, DNA-templated
0.59	GO:0006357	regulation of transcription by RNA polymerase II
0.52	GO:0006351	transcription, DNA-templated

0.77	GO:0016922	ligand-dependent nuclear receptor binding
0.75	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.74	GO:0004402	histone acetyltransferase activity
0.67	GO:0019904	protein domain specific binding
0.42	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.39	GO:0003700	DNA binding transcription factor activity

0.79	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.77	GO:0030914	STAGA complex
0.76	GO:0033276	transcription factor TFTC complex
0.71	GO:0072686	mitotic spindle
0.65	GO:0000124	SAGA complex

0.74

GO:0004402

sp|Q7SY23|AL4A1_DANRE
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
Search

ALDH4A1

0.59	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

0.78	GO:0010133	proline catabolic process to glutamate
0.53	GO:0055114	oxidation-reduction process
0.40	GO:0007005	mitochondrion organization
0.36	GO:0019470	4-hydroxyproline catabolic process
0.34	GO:0046487	glyoxylate metabolic process
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0006091	generation of precursor metabolites and energy

0.79	GO:0003842	1-pyrroline-5-carboxylate dehydrogenase activity
0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.46	GO:0042802	identical protein binding
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0009055	electron transfer activity

0.43	GO:0005739	mitochondrion
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:1.5.1.12

GO:0003842

sp|Q7SY24|KPCB_DANRE
Protein kinase C beta type
Search

PRKCB

0.92	Protein kinase C beta type

0.63	GO:0006468	protein phosphorylation
0.61	GO:0035556	intracellular signal transduction
0.55	GO:0050853	B cell receptor signaling pathway
0.54	GO:0050861	positive regulation of B cell receptor signaling pathway
0.54	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
0.54	GO:0018210	peptidyl-threonine modification
0.53	GO:0010829	negative regulation of glucose transport
0.53	GO:0042113	B cell activation
0.52	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.52	GO:0045766	positive regulation of angiogenesis

0.82	GO:0004697	protein kinase C activity
0.61	GO:0008270	zinc ion binding
0.58	GO:0035403	histone kinase activity (H3-T6 specific)
0.55	GO:0050681	androgen receptor binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0005080	protein kinase C binding

0.46	GO:0005829	cytosol
0.46	GO:0005654	nucleoplasm
0.41	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0005903	brush border
0.34	GO:0005813	centrosome
0.34	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0044425	membrane part

0.82

EC:2.7.11.13

GO:0004697

sp|Q7SY29|G6PT3_DANRE
Glucose-6-phosphate exchanger SLC37A2
Search

SLC37A2

0.95	Solute carrier family 37 (Glycerol-3-phosphate transporter), member 2

0.67	GO:0015760	glucose-6-phosphate transport
0.58	GO:0035435	phosphate ion transmembrane transport

0.69

GO:0061513

glucose 6-phosphate:inorganic phosphate antiporter activity

0.59	GO:0030176	integral component of endoplasmic reticulum membrane
0.42	GO:0070062	extracellular exosome

sp|Q7SY31|TM206_DANRE
Transmembrane protein 206
Search

TMEM206

0.97	Transmembrane protein 206

0.46	GO:0009986	cell surface
0.30	GO:0044425	membrane part

tr|Q7SY32|Q7SY32_DANRE
Phospholipid phosphatase-related 2a
Search

0.94	Lipid phosphate phosphatase-related protein type 5

0.45	GO:0046839	phospholipid dephosphorylation
0.41	GO:0006644	phospholipid metabolic process
0.39	GO:0007399	nervous system development
0.39	GO:0007165	signal transduction
0.38	GO:0051491	positive regulation of filopodium assembly
0.37	GO:0010720	positive regulation of cell development
0.37	GO:0051962	positive regulation of nervous system development
0.36	GO:0030154	cell differentiation

0.47	GO:0042577	lipid phosphatase activity
0.47	GO:0008195	phosphatidate phosphatase activity
0.32	GO:0003677	DNA binding

0.41	GO:0005887	integral component of plasma membrane
0.34	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part

0.47

EC:3.1.3.4

GO:0008195

tr|Q7SY45|Q7SY45_DANRE
Vesicle transport through interaction with t-SNAREs 1B
Search

VTI1B

0.96	Vesicle transport through interaction with t-SNAREsB

0.68	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.49	GO:0061025	membrane fusion
0.48	GO:0072666	establishment of protein localization to vacuole
0.47	GO:0048284	organelle fusion
0.47	GO:0016482	cytosolic transport
0.46	GO:0016050	vesicle organization
0.46	GO:0007034	vacuolar transport
0.46	GO:0016197	endosomal transport
0.46	GO:1903076	regulation of protein localization to plasma membrane

0.56	GO:0005484	SNAP receptor activity
0.51	GO:0000149	SNARE binding
0.48	GO:0019869	chloride channel inhibitor activity
0.35	GO:0052650	NADP-retinol dehydrogenase activity
0.32	GO:0015631	tubulin binding

0.53	GO:0005794	Golgi apparatus
0.51	GO:0031902	late endosome membrane
0.48	GO:0031201	SNARE complex
0.47	GO:0055038	recycling endosome membrane
0.47	GO:0012507	ER to Golgi transport vesicle membrane
0.47	GO:0031901	early endosome membrane
0.46	GO:0005765	lysosomal membrane
0.45	GO:0005829	cytosol
0.44	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005789	endoplasmic reticulum membrane

0.35	EC:1.1.1.300	GO:0052650
0.35	KEGG:R08379	GO:0052650

sp|Q7SY48|HEAT1_DANRE
HEAT repeat-containing protein 1
Search

HEATR1

0.96	HEAT repeat-containing protein 1

0.84	GO:0045943	positive regulation of transcription by RNA polymerase I
0.82	GO:2000234	positive regulation of rRNA processing
0.63	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.44	GO:0043487	regulation of RNA stability
0.43	GO:0043066	negative regulation of apoptotic process
0.40	GO:0006351	transcription, DNA-templated

0.64	GO:0030515	snoRNA binding
0.36	GO:0005515	protein binding

0.76	GO:0044452	nucleolar part
0.64	GO:0030686	90S preribosome
0.62	GO:0032040	small-subunit processome
0.56	GO:0005739	mitochondrion
0.49	GO:0043234	protein complex
0.37	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

sp|Q7SY49|CAMKV_DANRE
CaM kinase-like vesicle-associated protein
Search

CAMKV

0.97	CaM kinase like vesicle associated

0.62	GO:0006468	protein phosphorylation
0.49	GO:0018210	peptidyl-threonine modification
0.48	GO:0018209	peptidyl-serine modification
0.42	GO:0035556	intracellular signal transduction

0.62	GO:0004672	protein kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0005516	calmodulin binding

0.40	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0005886	plasma membrane

sp|Q7SY52|STK10_DANRE
Serine/threonine-protein kinase 10
Search

STK10

0.73	Serine/threonine-protein kinase 10

0.63	GO:0006468	protein phosphorylation
0.49	GO:2000401	regulation of lymphocyte migration
0.45	GO:0031098	stress-activated protein kinase signaling cascade
0.44	GO:0032147	activation of protein kinase activity
0.43	GO:0071593	lymphocyte aggregation
0.43	GO:0007346	regulation of mitotic cell cycle
0.43	GO:0042981	regulation of apoptotic process
0.37	GO:0007049	cell cycle
0.32	GO:0043312	neutrophil degranulation

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0042803	protein homodimerization activity

0.38	GO:0005886	plasma membrane
0.36	GO:0005737	cytoplasm
0.33	GO:0070062	extracellular exosome
0.32	GO:0012506	vesicle membrane
0.32	GO:0097708	intracellular vesicle
0.32	GO:0098805	whole membrane
0.32	GO:0098588	bounding membrane of organelle
0.32	GO:0012505	endomembrane system
0.31	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.70

GO:0004674

sp|Q7SY53|T23OB_DANRE
Tryptophan 2,3-dioxygenase B
Search

TDO2

0.63	Tryptophan 2,3-dioxygenase B

0.78	GO:0019441	tryptophan catabolic process to kynurenine
0.57	GO:0051289	protein homotetramerization
0.54	GO:0019442	tryptophan catabolic process to acetyl-CoA
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0033060	ocellus pigmentation
0.51	GO:0006726	eye pigment biosynthetic process
0.46	GO:0044550	secondary metabolite biosynthetic process
0.39	GO:0018130	heterocycle biosynthetic process
0.39	GO:1901362	organic cyclic compound biosynthetic process
0.39	GO:0019438	aromatic compound biosynthetic process

0.83	GO:0004833	tryptophan 2,3-dioxygenase activity
0.63	GO:0020037	heme binding
0.54	GO:0046872	metal ion binding
0.51	GO:0042802	identical protein binding
0.38	GO:0019825	oxygen binding
0.38	GO:0016597	amino acid binding
0.37	GO:0008234	cysteine-type peptidase activity

0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.83

EC:1.13.11.11

GO:0004833

sp|Q7SY54|AT2L1_DANRE
Ethanolamine-phosphate phospho-lyase
Search

ETNPPL

0.58	Ethanolamine-phosphate phospho-lyase

0.45	GO:0035162	embryonic hemopoiesis
0.34	GO:0006646	phosphatidylethanolamine biosynthetic process

0.69	GO:0008483	transaminase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.51	GO:0016829	lyase activity
0.44	GO:0042802	identical protein binding

0.40	GO:0005739	mitochondrion
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:2.6.1

GO:0008483

tr|Q7SY56|Q7SY56_DANRE
Ras-related associated with diabetes
Search

RRAD

0.92	GTP binding protein overexpressed in skeletal muscle

0.86	GO:1901841	regulation of high voltage-gated calcium channel activity
0.83	GO:1901386	negative regulation of voltage-gated calcium channel activity
0.61	GO:0007165	signal transduction
0.46	GO:0051310	metaphase plate congression
0.43	GO:0000278	mitotic cell cycle
0.40	GO:0051276	chromosome organization
0.34	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0005246	calcium channel regulator activity
0.40	GO:0000287	magnesium ion binding
0.35	GO:0005516	calmodulin binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0005509	calcium ion binding

0.45	GO:0051233	spindle midzone
0.45	GO:0030496	midbody
0.44	GO:0072686	mitotic spindle
0.43	GO:0009898	cytoplasmic side of plasma membrane
0.39	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|Q7SY59|Q7SY59_DANRE
RAP2B, member of RAS oncogene family
Search

RAP2B

0.96	RAP2B, member of RAS oncogene family

0.64	GO:0032486	Rap protein signal transduction
0.63	GO:0031954	positive regulation of protein autophosphorylation
0.59	GO:0030336	negative regulation of cell migration
0.57	GO:0061097	regulation of protein tyrosine kinase activity
0.53	GO:0070527	platelet aggregation
0.51	GO:0090557	establishment of endothelial intestinal barrier
0.47	GO:0030033	microvillus assembly
0.44	GO:0048814	regulation of dendrite morphogenesis
0.44	GO:0046328	regulation of JNK cascade
0.43	GO:0072659	protein localization to plasma membrane

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0019904	protein domain specific binding
0.46	GO:0003713	transcription coactivator activity
0.38	GO:0000287	magnesium ion binding

0.62	GO:0055038	recycling endosome membrane
0.58	GO:0044291	cell-cell contact zone
0.56	GO:0005923	bicellular tight junction
0.52	GO:0005829	cytosol
0.51	GO:0070062	extracellular exosome
0.50	GO:0045121	membrane raft
0.44	GO:0005886	plasma membrane
0.38	GO:0030496	midbody
0.36	GO:0070821	tertiary granule membrane
0.35	GO:0035579	specific granule membrane

sp|Q7SYB3|RYBPA_DANRE
RING1 and YY1-binding protein A
Search

0.97	RING1 and YY1-binding protein A

0.54	GO:0035518	histone H2A monoubiquitination
0.54	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.50	GO:0043065	positive regulation of apoptotic process
0.50	GO:0000122	negative regulation of transcription by RNA polymerase II
0.49	GO:0006915	apoptotic process
0.48	GO:0045893	positive regulation of transcription, DNA-templated
0.41	GO:0006351	transcription, DNA-templated

0.52	GO:0046872	metal ion binding
0.51	GO:0003714	transcription corepressor activity
0.44	GO:0003677	DNA binding

0.52	GO:0031519	PcG protein complex
0.46	GO:0005654	nucleoplasm
0.38	GO:0005737	cytoplasm

sp|Q7SYB5|DEFI6_DANRE
Differentially expressed in FDCP 6 homolog
Search

DEF6

0.93	Differentially expressed in FDCP 6

0.80	GO:0060027	convergent extension involved in gastrulation
0.79	GO:0042074	cell migration involved in gastrulation

0.44

GO:0005515

protein binding

0.53	GO:0030175	filopodium
0.51	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.46	GO:0005856	cytoskeleton
0.44	GO:0005911	cell-cell junction
0.41	GO:0005886	plasma membrane

tr|Q7SYB8|Q7SYB8_DANRE
Glycogen [starch] synthase
Search

GYS1

0.69	Glycogen [starch] synthase, muscle

0.77	GO:0005978	glycogen biosynthetic process
0.48	GO:0007507	heart development
0.36	GO:0009749	response to glucose
0.35	GO:0090664	response to high population density
0.34	GO:0032868	response to insulin

0.80	GO:0004373	glycogen (starch) synthase activity
0.48	GO:0019901	protein kinase binding
0.39	GO:0061547	glycogen synthase activity, transferring glucose-1-phosphate
0.37	GO:0005536	glucose binding
0.34	GO:0009011	starch synthase activity

0.50	GO:0016234	inclusion body
0.37	GO:0005737	cytoplasm
0.34	GO:0099512	supramolecular fiber
0.34	GO:0015629	actin cytoskeleton
0.33	GO:0044430	cytoskeletal part
0.32	GO:0071944	cell periphery
0.30	GO:0016020	membrane

0.80

EC:2.4.1.11

GO:0004373

sp|Q7SYC7|T185L_DANRE
Transmembrane protein 185-like
Search

TMEM185A

0.50	Transmembrane protein 185B

0.30

GO:0044425

membrane part

sp|Q7SYC9|CTL2_DANRE
Choline transporter-like protein 2
Search

SLC44A2

0.93	Solute carrier family 44 (choline transporter), member 2

0.36	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0006656	phosphatidylcholine biosynthetic process
0.34	GO:0015871	choline transport
0.34	GO:0007165	signal transduction
0.32	GO:0055085	transmembrane transport

0.34	GO:0015220	choline transmembrane transporter activity
0.34	GO:0004871	signal transducer activity
0.34	GO:0003725	double-stranded RNA binding
0.33	GO:0005515	protein binding

0.36	GO:0005765	lysosomal membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0035579	specific granule membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q7SYD0|Q7SYD0_DANRE
Carbonyl reductase 1
Search

CBR1

0.77	20-beta-hydroxysteroid dehydrogenase subtype I

0.52	GO:0055114	oxidation-reduction process
0.46	GO:0042373	vitamin K metabolic process
0.42	GO:0050890	cognition
0.42	GO:0030855	epithelial cell differentiation
0.39	GO:0042376	phylloquinone catabolic process
0.38	GO:0017144	drug metabolic process
0.36	GO:0006692	prostanoid metabolic process
0.35	GO:1901523	icosanoid catabolic process
0.35	GO:0001542	ovulation from ovarian follicle
0.35	GO:0033574	response to testosterone

0.53	GO:0016491	oxidoreductase activity
0.41	GO:0070402	NADPH binding
0.33	GO:0005515	protein binding

0.39	GO:0005829	cytosol
0.39	GO:0005654	nucleoplasm
0.36	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.34	GO:0005902	microvillus
0.32	GO:0005886	plasma membrane

0.53

GO:0016491

sp|Q7SYD5|SC31A_DANRE
Protein transport protein Sec31A
Search

SEC31A

0.92	SEC31 homolog A, COPII coat complex component

0.83	GO:0090110	cargo loading into COPII-coated vesicle
0.79	GO:0051592	response to calcium ion
0.47	GO:0001889	liver development
0.47	GO:0055123	digestive system development
0.46	GO:0007029	endoplasmic reticulum organization
0.46	GO:0015031	protein transport

0.80

GO:0048306

calcium-dependent protein binding

0.81	GO:0070971	endoplasmic reticulum exit site
0.77	GO:0030127	COPII vesicle coat
0.74	GO:0048471	perinuclear region of cytoplasm
0.69	GO:0000139	Golgi membrane
0.65	GO:0005829	cytosol
0.48	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0005768	endosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q7SYD9|INT6_DANRE
Integrator complex subunit 6
Search

0.84	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

sp|Q7SYE0|ATG13_DANRE
Autophagy-related protein 13
Search

ATG13

0.73	Autophagy-related protein 13

0.77	GO:0006914	autophagy
0.50	GO:0098780	response to mitochondrial depolarisation
0.49	GO:1903955	positive regulation of protein targeting to mitochondrion
0.49	GO:0061726	mitochondrion disassembly
0.48	GO:0007033	vacuole organization
0.45	GO:0070925	organelle assembly
0.35	GO:0016241	regulation of macroautophagy

0.48

GO:0019901

protein kinase binding

0.85	GO:1990316	Atg1/ULK1 kinase complex
0.49	GO:0000407	phagophore assembly site
0.44	GO:0005829	cytosol
0.41	GO:0005739	mitochondrion
0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q7SYH6|Q7SYH6_DANRE
Pah
Search

PAH

0.63	Phenylalanine hydroxylase

0.78	GO:0006559	L-phenylalanine catabolic process
0.53	GO:0055114	oxidation-reduction process
0.46	GO:0071391	cellular response to estrogen stimulus
0.35	GO:0042423	catecholamine biosynthetic process
0.34	GO:0018126	protein hydroxylation
0.34	GO:0006726	eye pigment biosynthetic process
0.34	GO:0007616	long-term memory
0.34	GO:0046146	tetrahydrobiopterin metabolic process
0.34	GO:0006571	tyrosine biosynthetic process
0.34	GO:0042136	neurotransmitter biosynthetic process

0.83	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
0.63	GO:0005506	iron ion binding
0.34	GO:0016597	amino acid binding
0.34	GO:0042803	protein homodimerization activity
0.33	GO:0004252	serine-type endopeptidase activity
0.32	GO:0048037	cofactor binding

0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol

0.83

EC:1.14.16

GO:0016714

sp|Q7SYI5|C1GTB_DANRE
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-B
Search

0.85	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-B

0.75	GO:0016266	O-glycan processing
0.51	GO:0060576	intestinal epithelial cell development
0.51	GO:0001525	angiogenesis
0.49	GO:0001822	kidney development

0.79	GO:0016263	glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity
0.44	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.33	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

0.79

EC:2.4.1.122

GO:0016263

tr|Q7SYI9|Q7SYI9_DANRE
Zgc:66475
Search

0.52	Deoxyribodipyrimidine photo-lyase

0.64	GO:0006281	DNA repair
0.39	GO:0009650	UV protection
0.36	GO:0018298	protein-chromophore linkage
0.33	GO:0006364	rRNA processing
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.84	GO:0003904	deoxyribodipyrimidine photo-lyase activity
0.36	GO:0071949	FAD binding
0.34	GO:0008408	3'-5' exonuclease activity
0.33	GO:0003677	DNA binding

0.30

GO:0031224

intrinsic component of membrane

0.84

EC:4.1.99.3

GO:0003904

tr|Q7SYJ3|Q7SYJ3_DANRE
Zgc:66442
Search

ZBTB14

0.97	Zinc finger and BTB domain-containing protein 14

0.54	GO:0060976	coronary vasculature development
0.54	GO:0003170	heart valve development
0.53	GO:0003279	cardiac septum development
0.50	GO:0045892	negative regulation of transcription, DNA-templated
0.47	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0007016	cytoskeletal anchoring at plasma membrane
0.36	GO:0030866	cortical actin cytoskeleton organization
0.35	GO:0001558	regulation of cell growth
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:0016567	protein ubiquitination

0.53	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0046872	metal ion binding
0.35	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0005515	protein binding
0.33	GO:0005198	structural molecule activity
0.33	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding

0.55	GO:0016235	aggresome
0.49	GO:0005730	nucleolus
0.48	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.36	GO:0031463	Cul3-RING ubiquitin ligase complex
0.35	GO:0005911	cell-cell junction
0.34	GO:0005856	cytoskeleton
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0004842

tr|Q7SYJ6|Q7SYJ6_DANRE
Cytochrome P450, family 11, subfamily A, polypeptide 1
Search

0.93	Cholesterol side-chain cleavage enzyme, mitochondrial

0.83	GO:0006700	C21-steroid hormone biosynthetic process
0.75	GO:0008203	cholesterol metabolic process
0.53	GO:0055114	oxidation-reduction process
0.48	GO:0034650	cortisol metabolic process
0.45	GO:0032341	aldosterone metabolic process
0.45	GO:0006705	mineralocorticoid biosynthetic process
0.43	GO:0090504	epiboly
0.43	GO:0031116	positive regulation of microtubule polymerization
0.43	GO:0006704	glucocorticoid biosynthetic process
0.42	GO:0035865	cellular response to potassium ion

0.81	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.48	GO:0004507	steroid 11-beta-monooxygenase activity
0.43	GO:0047783	corticosterone 18-monooxygenase activity
0.33	GO:0004743	pyruvate kinase activity
0.33	GO:0030955	potassium ion binding
0.32	GO:0000287	magnesium ion binding
0.32	GO:0016301	kinase activity

0.57	GO:0005739	mitochondrion
0.57	GO:0031967	organelle envelope
0.56	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:1.14.15.6

GO:0008386

sp|Q7SYJ9|SPAG7_DANRE
Sperm-associated antigen 7 homolog
Search

SPAG7

0.97	Sperm-associated antigen 7

0.51

GO:0003676

nucleic acid binding

0.49	GO:0005634	nucleus
0.30	GO:0044425	membrane part

sp|Q7SYK0|CHID1_DANRE
Chitinase domain-containing protein 1
Search

CHID1

0.93	Chitinase domain-containing protein 1

0.59	GO:0005975	carbohydrate metabolic process
0.50	GO:1900016	negative regulation of cytokine production involved in inflammatory response
0.47	GO:0006032	chitin catabolic process
0.45	GO:0006954	inflammatory response
0.39	GO:0045087	innate immune response
0.35	GO:0002576	platelet degranulation

0.75	GO:0008061	chitin binding
0.49	GO:0070492	oligosaccharide binding
0.47	GO:0004568	chitinase activity
0.33	GO:0005515	protein binding

0.49	GO:0005764	lysosome
0.47	GO:0005770	late endosome
0.47	GO:0005802	trans-Golgi network
0.45	GO:0005576	extracellular region
0.35	GO:0005775	vacuolar lumen
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.47

EC:3.2.1.14

GO:0004568

sp|Q7SYK1|TGT_DANRE
Queuine tRNA-ribosyltransferase catalytic subunit 1
Search

QTRT1

0.46	Queuine tRNA-ribosyltransferase

0.76	GO:0101030	tRNA-guanine transglycosylation
0.36	GO:0006813	potassium ion transport
0.34	GO:0008616	queuosine biosynthetic process

0.77	GO:0008479	queuine tRNA-ribosyltransferase activity
0.50	GO:0046872	metal ion binding
0.49	GO:0042803	protein homodimerization activity
0.49	GO:0046982	protein heterodimerization activity

0.63	GO:0005741	mitochondrial outer membrane
0.42	GO:0005634	nucleus
0.42	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.77

EC:2.4.2.29

GO:0008479

tr|Q7SYK5|Q7SYK5_DANRE
Integral membrane protein 2Cb
Search

0.97	Integral membrane protein 2Cb

0.53	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway
0.52	GO:0010977	negative regulation of neuron projection development
0.49	GO:0030182	neuron differentiation
0.47	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process

0.54	GO:0001540	amyloid-beta binding
0.40	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.51	GO:0005764	lysosome
0.50	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0005794	Golgi apparatus
0.44	GO:0070062	extracellular exosome
0.41	GO:0005886	plasma membrane
0.40	GO:0098852	lytic vacuole membrane
0.30	GO:0016021	integral component of membrane

tr|Q7SYK7|Q7SYK7_DANRE
Aspartate aminotransferase
Search

GOT2

0.49	Aspartate aminotransferase

0.60	GO:0006520	cellular amino acid metabolic process
0.52	GO:0043649	dicarboxylic acid catabolic process
0.51	GO:0045471	response to ethanol
0.49	GO:0015908	fatty acid transport
0.49	GO:0009058	biosynthetic process
0.48	GO:0006103	2-oxoglutarate metabolic process
0.46	GO:1901565	organonitrogen compound catabolic process
0.46	GO:0006107	oxaloacetate metabolic process
0.45	GO:0006106	fumarate metabolic process
0.41	GO:0042537	benzene-containing compound metabolic process

0.81	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity
0.78	GO:0070546	L-phenylalanine aminotransferase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.44	GO:0016212	kynurenine-oxoglutarate transaminase activity
0.37	GO:0042803	protein homodimerization activity
0.36	GO:0016597	amino acid binding
0.36	GO:0005543	phospholipid binding
0.36	GO:0019899	enzyme binding
0.36	GO:0047578	4-hydroxyglutamate transaminase activity
0.34	GO:0090729	toxin activity

0.46	GO:0043209	myelin sheath
0.44	GO:0005739	mitochondrion
0.40	GO:0005886	plasma membrane
0.40	GO:0019866	organelle inner membrane
0.40	GO:0070013	intracellular organelle lumen
0.38	GO:0043204	perikaryon
0.37	GO:0009986	cell surface
0.36	GO:0070062	extracellular exosome
0.34	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.81	EC:2.6.1.1	GO:0004069
0.81	KEGG:R00355	GO:0004069

sp|Q7SYL1|AR2BP_DANRE
ADP-ribosylation factor-like protein 2-binding protein
Search

ARL2BP

0.96	Binder of Arl Two

0.85	GO:0051457	maintenance of protein location in nucleus
0.85	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.56	GO:2001141	regulation of RNA biosynthetic process
0.40	GO:0050790	regulation of catalytic activity
0.40	GO:0050796	regulation of insulin secretion
0.36	GO:0007165	signal transduction

0.77	GO:0003713	transcription coactivator activity
0.42	GO:0030695	GTPase regulator activity
0.39	GO:0005515	protein binding
0.38	GO:0008047	enzyme activator activity

0.80	GO:0030496	midbody
0.79	GO:0005758	mitochondrial intermembrane space
0.76	GO:0005815	microtubule organizing center
0.61	GO:0005634	nucleus
0.56	GO:0005929	cilium
0.55	GO:0005819	spindle
0.38	GO:0005759	mitochondrial matrix
0.37	GO:0005829	cytosol

sp|Q7SYL3|SIAH2_DANRE
E3 ubiquitin-protein ligase Siah2
Search

SIAH2

0.56	E3 ubiquitin-protein ligase

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.73	GO:0016567	protein ubiquitination
0.70	GO:0007275	multicellular organism development
0.52	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.52	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.52	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.38	GO:0031396	regulation of protein ubiquitination
0.37	GO:0006915	apoptotic process
0.36	GO:0007049	cell cycle
0.36	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway

0.63	GO:0008270	zinc ion binding
0.52	GO:0016874	ligase activity
0.39	GO:0031624	ubiquitin conjugating enzyme binding
0.38	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0008022	protein C-terminus binding
0.35	GO:0061659	ubiquitin-like protein ligase activity
0.35	GO:0042802	identical protein binding
0.34	GO:0003714	transcription corepressor activity

0.61	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.45	GO:0031974	membrane-enclosed lumen
0.41	GO:0044446	intracellular organelle part
0.38	GO:0043025	neuronal cell body
0.38	GO:0005769	early endosome
0.38	GO:0043005	neuron projection
0.36	GO:0030877	beta-catenin destruction complex

0.52	EC:6	GO:0016874
0.38	KEGG:R03876	GO:0004842

sp|Q7SYM0|UCK2A_DANRE
Uridine-cytidine kinase 2-A
Search

UCK2

0.87	Uridine-cytidine kinase

0.85	GO:0006238	CMP salvage
0.77	GO:0044206	UMP salvage
0.68	GO:0044211	CTP salvage
0.57	GO:0016310	phosphorylation
0.44	GO:0006206	pyrimidine nucleobase metabolic process
0.35	GO:0048678	response to axon injury
0.35	GO:0007631	feeding behavior
0.35	GO:0071453	cellular response to oxygen levels
0.34	GO:0016579	protein deubiquitination

0.76	GO:0019206	nucleoside kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.43	GO:0005829	cytosol
0.32	GO:0043231	intracellular membrane-bounded organelle

tr|Q7SYM1|Q7SYM1_DANRE
Forkhead box K1
Search

FOXK1

0.83	Winged helix/forkhead transcription factor FoxK

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0051254	positive regulation of RNA metabolic process
0.48	GO:0010557	positive regulation of macromolecule biosynthetic process
0.48	GO:0031328	positive regulation of cellular biosynthetic process
0.46	GO:0030154	cell differentiation
0.46	GO:0009653	anatomical structure morphogenesis
0.43	GO:0051253	negative regulation of RNA metabolic process
0.43	GO:0010558	negative regulation of macromolecule biosynthetic process

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.40	GO:0000287	magnesium ion binding
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.38	GO:0044599	AP-5 adaptor complex
0.33	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q7SYN4|5NT3_DANRE
Cytosolic 5'-nucleotidase 3
Search

NT5C3A

0.47	Cytosolic 5'-nucleotidase 3

0.68	GO:0016311	dephosphorylation
0.57	GO:0009117	nucleotide metabolic process
0.49	GO:0051607	defense response to virus
0.38	GO:0046085	adenosine metabolic process
0.34	GO:0046135	pyrimidine nucleoside catabolic process

0.79	GO:0008253	5'-nucleotidase activity
0.64	GO:0000287	magnesium ion binding
0.51	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.35	GO:0000215	tRNA 2'-phosphotransferase activity

0.49	GO:0005737	cytoplasm
0.45	GO:0012505	endomembrane system
0.40	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0034464	BBSome
0.30	GO:0016020	membrane

0.79

EC:3.1.3.5

GO:0008253

sp|Q7SYN5|RXRBA_DANRE
Retinoic acid receptor RXR-beta-A
Search

0.90	Retinoic acid receptor RXR-beta-A

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.44	GO:0030522	intracellular receptor signaling pathway
0.41	GO:0051254	positive regulation of RNA metabolic process
0.41	GO:0010557	positive regulation of macromolecule biosynthetic process
0.41	GO:0031328	positive regulation of cellular biosynthetic process
0.37	GO:0060038	cardiac muscle cell proliferation

0.80	GO:0003707	steroid hormone receptor activity
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.43	GO:0001012	RNA polymerase II regulatory region DNA binding
0.41	GO:0003690	double-stranded DNA binding
0.36	GO:0035326	enhancer binding
0.36	GO:0003713	transcription coactivator activity
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

tr|Q7SZ49|Q7SZ49_DANRE
Short chain dehydrogenase/reductase family 16C, member 5
Search

SDR16C5

0.92	LOW QUALITY PROTEIN: epidermal retinol dehydrogenase 2

0.47	GO:0055114	oxidation-reduction process
0.39	GO:0043616	keratinocyte proliferation
0.39	GO:0042574	retinal metabolic process
0.39	GO:0031065	positive regulation of histone deacetylation
0.39	GO:0035067	negative regulation of histone acetylation
0.38	GO:0042572	retinol metabolic process
0.37	GO:0000122	negative regulation of transcription by RNA polymerase II

0.48	GO:0016491	oxidoreductase activity
0.38	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.38	GO:0033613	activating transcription factor binding

0.38	GO:0017053	transcriptional repressor complex
0.36	GO:0000785	chromatin
0.36	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0005811	lipid droplet
0.35	GO:0005634	nucleus
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.48

GO:0016491

sp|Q7SZ56|TM218_DANRE
Transmembrane protein 218
Search

TMEM218

0.97	Transmembrane protein 218

0.34

GO:0005515

protein binding

0.44	GO:0005929	cilium
0.30	GO:0044425	membrane part

sp|Q7SZ59|RASLC_DANRE
Ras-like protein family member 12
Search

RASL12

0.97	Ras-like protein family member 12-like

0.60	GO:0007165	signal transduction
0.33	GO:0045762	positive regulation of adenylate cyclase activity
0.33	GO:0097271	protein localization to bud neck
0.33	GO:0001302	replicative cell aging
0.32	GO:0042147	retrograde transport, endosome to Golgi

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.32	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q7SZ61|Q7SZ61_DANRE
G protein pathway suppressor 2
Search

GPS2

0.97	G protein pathway suppressor 2

0.85	GO:0046329	negative regulation of JNK cascade
0.79	GO:0045599	negative regulation of fat cell differentiation
0.78	GO:0000122	negative regulation of transcription by RNA polymerase II
0.42	GO:0034260	negative regulation of GTPase activity
0.42	GO:0007254	JNK cascade
0.41	GO:0000188	inactivation of MAPK activity

0.82	GO:0030332	cyclin binding
0.81	GO:0003714	transcription corepressor activity
0.43	GO:0005095	GTPase inhibitor activity
0.34	GO:0005509	calcium ion binding
0.33	GO:0004674	protein serine/threonine kinase activity

0.81	GO:0017053	transcriptional repressor complex
0.57	GO:0005634	nucleus
0.38	GO:0070013	intracellular organelle lumen
0.36	GO:0044446	intracellular organelle part

0.33

GO:0004674

sp|Q7SZC2|XPO2_DANRE
Exportin-2
Search

CSE1L

0.90	Putative nuclear export receptor cse1/cas importin beta superfamily

0.69	GO:0006886	intracellular protein transport
0.48	GO:0006611	protein export from nucleus
0.47	GO:0006606	protein import into nucleus
0.46	GO:0007589	body fluid secretion
0.36	GO:0032012	regulation of ARF protein signal transduction
0.34	GO:0065009	regulation of molecular function
0.34	GO:0008283	cell proliferation
0.34	GO:0006915	apoptotic process

0.78	GO:0008536	Ran GTPase binding
0.49	GO:0005049	nuclear export signal receptor activity
0.36	GO:0005086	ARF guanyl-nucleotide exchange factor activity

0.59	GO:0005634	nucleus
0.48	GO:0005829	cytosol
0.46	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.42	GO:0012505	endomembrane system
0.40	GO:0031975	envelope
0.36	GO:0070062	extracellular exosome
0.35	GO:0009925	basal plasma membrane
0.35	GO:0016328	lateral plasma membrane
0.35	GO:0016324	apical plasma membrane

sp|Q7SZC5|NDC1_DANRE
Nucleoporin NDC1
Search

NDC1

0.90	NDC1 transmembrane nucleoporin

0.58	GO:0006999	nuclear pore organization
0.57	GO:0031081	nuclear pore distribution
0.56	GO:0046931	pore complex assembly
0.54	GO:0007129	synapsis
0.52	GO:0007283	spermatogenesis
0.51	GO:0070632	establishment of spindle pole body localization
0.51	GO:0071789	spindle pole body localization to nuclear envelope
0.49	GO:0030474	spindle pole body duplication
0.49	GO:0043623	cellular protein complex assembly
0.40	GO:0051028	mRNA transport

0.55

GO:0017056

structural constituent of nuclear pore

0.54	GO:0005643	nuclear pore
0.54	GO:0031965	nuclear membrane
0.50	GO:0015629	actin cytoskeleton
0.47	GO:0005816	spindle pole body
0.42	GO:0005886	plasma membrane
0.38	GO:0005737	cytoplasm
0.33	GO:0044215	other organism
0.30	GO:0031224	intrinsic component of membrane

tr|Q7SZC7|Q7SZC7_DANRE
Progesterone receptor membrane component 2
Search

PGRMC2

0.91	membrane-associated progesterone receptor component 2

0.47	GO:1903538	regulation of meiotic cell cycle process involved in oocyte maturation
0.34	GO:0043401	steroid hormone mediated signaling pathway

0.43	GO:0020037	heme binding
0.39	GO:0005496	steroid binding
0.35	GO:0003707	steroid hormone receptor activity
0.34	GO:0005515	protein binding

0.49	GO:0005635	nuclear envelope
0.35	GO:0030868	smooth endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q7SZE3|L2GL2_DANRE
Lethal(2) giant larvae protein homolog 2
Search

LLGL2

0.87	LLGL2, scribble cell polarity complex component

0.69	GO:0032878	regulation of establishment or maintenance of cell polarity
0.63	GO:0017157	regulation of exocytosis
0.61	GO:0050708	regulation of protein secretion
0.59	GO:0043547	positive regulation of GTPase activity
0.53	GO:0030866	cortical actin cytoskeleton organization
0.47	GO:0006461	protein complex assembly
0.46	GO:0016332	establishment or maintenance of polarity of embryonic epithelium
0.45	GO:0048513	animal organ development
0.44	GO:0048916	posterior lateral line development
0.44	GO:0035264	multicellular organism growth

0.76	GO:0030165	PDZ domain binding
0.64	GO:0019905	syntaxin binding
0.62	GO:0017137	Rab GTPase binding
0.59	GO:0005096	GTPase activator activity
0.51	GO:0019901	protein kinase binding

0.61	GO:0005829	cytosol
0.52	GO:0030864	cortical actin cytoskeleton
0.51	GO:0043231	intracellular membrane-bounded organelle
0.46	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q7SZE5|SC23A_DANRE
Protein transport protein Sec23A
Search

SEC23A

0.97	Sec23 homolog A, COPII coat complex component

0.81	GO:0090114	COPII-coated vesicle budding
0.69	GO:0006886	intracellular protein transport
0.64	GO:0035459	cargo loading into vesicle
0.61	GO:0051668	localization within membrane
0.56	GO:0048702	embryonic neurocranium morphogenesis
0.53	GO:0035138	pectoral fin morphogenesis
0.53	GO:0051216	cartilage development
0.42	GO:0048821	erythrocyte development

0.63

GO:0008270

zinc ion binding

0.80	GO:0030127	COPII vesicle coat
0.73	GO:0000139	Golgi membrane
0.63	GO:0070971	endoplasmic reticulum exit site
0.61	GO:0048471	perinuclear region of cytoplasm
0.56	GO:0019898	extrinsic component of membrane
0.52	GO:0005829	cytosol

sp|Q7SZE8|TP8L1_DANRE
Tumor necrosis factor alpha-induced protein 8-like protein 1
Search

TNFAIP8L1

0.91	Tumor necrosis factor alpha-induced protein 8

0.71	GO:0042981	regulation of apoptotic process
0.41	GO:0032007	negative regulation of TOR signaling
0.40	GO:2000117	negative regulation of cysteine-type endopeptidase activity
0.39	GO:0043068	positive regulation of programmed cell death
0.39	GO:0043069	negative regulation of programmed cell death
0.38	GO:0006915	apoptotic process
0.35	GO:0032611	interleukin-1 beta production
0.35	GO:0050830	defense response to Gram-positive bacterium

0.40	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.33	GO:0005515	protein binding

0.36	GO:0005654	nucleoplasm
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q7SZF1|CE022_DANRE
UPF0489 protein C5orf22 homolog
Search

0.46	GO:0005515	protein binding
0.39	GO:0004386	helicase activity
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0003676	nucleic acid binding

0.30

GO:0031224

intrinsic component of membrane

tr|Q7SZF3|Q7SZF3_DANRE
Dual specificity protein phosphatase
Search

0.71	Dual specificity protein phosphatase

0.84	GO:0000188	inactivation of MAPK activity
0.73	GO:0035335	peptidyl-tyrosine dephosphorylation
0.53	GO:0001706	endoderm formation
0.51	GO:0035970	peptidyl-threonine dephosphorylation
0.49	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.45	GO:0060795	cell fate commitment involved in formation of primary germ layer
0.45	GO:0001708	cell fate specification
0.40	GO:0042981	regulation of apoptotic process
0.38	GO:0033574	response to testosterone
0.38	GO:0071850	mitotic cell cycle arrest

0.84	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.52	GO:0008330	protein tyrosine/threonine phosphatase activity
0.50	GO:1990439	MAP kinase serine/threonine phosphatase activity
0.37	GO:0019838	growth factor binding

0.43	GO:0005634	nucleus
0.41	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part
0.35	GO:0005737	cytoplasm

0.84

GO:0017017

sp|Q7SZK7|OFD1_DANRE
Oral-facial-digital syndrome 1 protein homolog
Search

OFD1

0.80	Oral-facial-digital syndrome 1

0.76	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry
0.66	GO:0060027	convergent extension involved in gastrulation
0.64	GO:0061371	determination of heart left/right asymmetry
0.64	GO:0030030	cell projection organization
0.55	GO:0007099	centriole replication
0.55	GO:0090307	mitotic spindle assembly
0.52	GO:2000314	negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
0.48	GO:0010172	embryonic body morphogenesis
0.48	GO:0000086	G2/M transition of mitotic cell cycle
0.47	GO:0001578	microtubule bundle formation

0.58	GO:0042802	identical protein binding
0.56	GO:0043014	alpha-tubulin binding
0.53	GO:0043015	gamma-tubulin binding

0.77	GO:0036064	ciliary basal body
0.76	GO:0005814	centriole
0.72	GO:0005813	centrosome
0.54	GO:0005634	nucleus
0.42	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q7SZN2|RN170_DANRE
E3 ubiquitin-protein ligase RNF170
Search

RNF170

0.92	Ring finger protein 170

0.39	GO:0016567	protein ubiquitination
0.35	GO:0043009	chordate embryonic development

0.53	GO:0046872	metal ion binding
0.50	GO:0016874	ligase activity
0.35	GO:0016740	transferase activity
0.33	GO:0005515	protein binding

0.39	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.50

GO:0016874

tr|Q7SZN7|Q7SZN7_DANRE
Enah/Vasp-like a
Search

EVL

0.85	Ena-vasodilator stimulated phosphoprotein

0.79	GO:0051289	protein homotetramerization
0.78	GO:0008154	actin polymerization or depolymerization
0.73	GO:0045010	actin nucleation
0.52	GO:1900028	negative regulation of ruffle assembly
0.50	GO:0051496	positive regulation of stress fiber assembly
0.50	GO:0010633	negative regulation of epithelial cell migration
0.49	GO:0071346	cellular response to interferon-gamma
0.37	GO:0007411	axon guidance
0.35	GO:0030048	actin filament-based movement
0.35	GO:0030168	platelet activation

0.75	GO:0017124	SH3 domain binding
0.69	GO:0003779	actin binding
0.52	GO:0005522	profilin binding

0.65	GO:0005856	cytoskeleton
0.51	GO:0042995	cell projection
0.49	GO:0005925	focal adhesion
0.49	GO:0045335	phagocytic vesicle
0.48	GO:0031252	cell leading edge
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q7SZP2|CA052_DANRE
UPF0690 protein C1orf52 homolog
Search

0.40	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.38	GO:0006915	apoptotic process
0.38	GO:0042981	regulation of apoptotic process

0.38

GO:0003723

RNA binding

0.59

GO:0005634

nucleus

tr|Q7SZP4|Q7SZP4_DANRE
Zgc:65851
Search

0.81	Internexin neuronal intermediate filament protein alpha

0.72	GO:0007399	nervous system development
0.64	GO:0120036	plasma membrane bounded cell projection organization
0.63	GO:0048468	cell development
0.49	GO:0033693	neurofilament bundle assembly
0.49	GO:1902513	regulation of organelle transport along microtubule
0.46	GO:1990823	response to leukemia inhibitory factor
0.46	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.44	GO:0071345	cellular response to cytokine stimulus
0.43	GO:0000226	microtubule cytoskeleton organization
0.36	GO:0006334	nucleosome assembly

0.62	GO:0005198	structural molecule activity
0.44	GO:0019901	protein kinase binding
0.35	GO:0005219	ryanodine-sensitive calcium-release channel activity
0.35	GO:0030674	protein binding, bridging
0.34	GO:0019894	kinesin binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0070840	dynein complex binding
0.34	GO:0015643	toxic substance binding
0.33	GO:0003677	DNA binding
0.33	GO:0008017	microtubule binding

0.84	GO:0005883	neurofilament
0.49	GO:0097418	neurofibrillary tangle
0.46	GO:0043209	myelin sheath
0.45	GO:0014069	postsynaptic density
0.44	GO:0030424	axon
0.39	GO:0005739	mitochondrion
0.37	GO:0031965	nuclear membrane
0.37	GO:0036464	cytoplasmic ribonucleoprotein granule
0.36	GO:0005654	nucleoplasm
0.36	GO:0000786	nucleosome

tr|Q7SZP8|Q7SZP8_DANRE
Transducer of ERBB2, 1b
Search

TOB1

0.96	Transducer of ERBB2, 1

0.79	GO:0008285	negative regulation of cell proliferation
0.58	GO:0060212	negative regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.56	GO:0007184	SMAD protein import into nucleus
0.55	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.54	GO:0030278	regulation of ossification
0.53	GO:0030514	negative regulation of BMP signaling pathway
0.52	GO:0045596	negative regulation of cell differentiation
0.52	GO:0051241	negative regulation of multicellular organismal process
0.50	GO:0017148	negative regulation of translation
0.50	GO:1903507	negative regulation of nucleic acid-templated transcription

0.54	GO:0003714	transcription corepressor activity
0.54	GO:0030971	receptor tyrosine kinase binding
0.53	GO:0046332	SMAD binding
0.42	GO:0042809	vitamin D receptor binding
0.34	GO:0005070	SH3/SH2 adaptor activity

0.52	GO:0030014	CCR4-NOT complex
0.42	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm

sp|Q7SZP9|APJA_DANRE
Apelin receptor A
Search

0.97	Apelin receptor A

0.67	GO:0007186	G-protein coupled receptor signaling pathway
0.60	GO:0048514	blood vessel morphogenesis
0.60	GO:1904325	positive regulation of inhibitory G-protein coupled receptor phosphorylation
0.60	GO:0007507	heart development
0.58	GO:0043951	negative regulation of cAMP-mediated signaling
0.57	GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.57	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.56	GO:1900107	regulation of nodal signaling pathway
0.55	GO:0030154	cell differentiation
0.55	GO:0007369	gastrulation

0.68	GO:0004930	G-protein coupled receptor activity
0.46	GO:0001653	peptide receptor activity
0.34	GO:0042277	peptide binding

0.42	GO:0005886	plasma membrane
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q7SZQ0|MBOA7_DANRE
Lysophospholipid acyltransferase 7
Search

MBOAT7

0.97	Membrane bound O-acyltransferase domain containing 7

0.55	GO:0021819	layer formation in cerebral cortex
0.54	GO:0021591	ventricular system development
0.48	GO:0046488	phosphatidylinositol metabolic process
0.38	GO:0008654	phospholipid biosynthetic process

0.57	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0005515	protein binding

0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.57

EC:2.3

GO:0016746

tr|Q7SZQ2|Q7SZQ2_DANRE
Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
Search

ID2

0.97	Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.56	GO:0061031	endodermal digestive tract morphogenesis
0.55	GO:0045664	regulation of neuron differentiation
0.55	GO:0045777	positive regulation of blood pressure
0.55	GO:0045578	negative regulation of B cell differentiation
0.55	GO:0048557	embryonic digestive tract morphogenesis
0.55	GO:0003166	bundle of His development
0.54	GO:0090398	cellular senescence
0.54	GO:2000178	negative regulation of neural precursor cell proliferation
0.54	GO:0071158	positive regulation of cell cycle arrest

0.68	GO:0046983	protein dimerization activity
0.53	GO:0044325	ion channel binding
0.46	GO:0003677	DNA binding
0.40	GO:0043425	bHLH transcription factor binding
0.38	GO:1901707	leptomycin B binding
0.36	GO:0019904	protein domain specific binding
0.35	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.42	GO:0043234	protein complex
0.34	GO:0000785	chromatin

sp|Q7SZQ4|MFFB_DANRE
Mitochondrial fission factor homolog B
Search

MFF

0.89	Mitochondrial fission factor

0.45	GO:0090141	positive regulation of mitochondrial fission
0.45	GO:0000266	mitochondrial fission
0.45	GO:0090314	positive regulation of protein targeting to membrane
0.41	GO:0008053	mitochondrial fusion
0.38	GO:1900063	regulation of peroxisome organization
0.38	GO:1900244	positive regulation of synaptic vesicle endocytosis
0.38	GO:0010666	positive regulation of cardiac muscle cell apoptotic process
0.38	GO:0043653	mitochondrial fragmentation involved in apoptotic process
0.37	GO:0001836	release of cytochrome c from mitochondria
0.37	GO:0090200	positive regulation of release of cytochrome c from mitochondria

0.42	GO:0042803	protein homodimerization activity
0.37	GO:0032296	double-stranded RNA-specific ribonuclease activity
0.37	GO:0005201	extracellular matrix structural constituent
0.36	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters
0.36	GO:0032403	protein complex binding
0.36	GO:0051020	GTPase binding

0.43	GO:0005741	mitochondrial outer membrane
0.43	GO:0005777	peroxisome
0.41	GO:0008021	synaptic vesicle
0.39	GO:0030054	cell junction
0.38	GO:0032592	integral component of mitochondrial membrane
0.37	GO:0099501	exocytic vesicle membrane
0.37	GO:0005604	basement membrane
0.36	GO:0005581	collagen trimer

0.36

EC:3.1.26

GO:0016891

sp|Q7SZQ7|SURF4_DANRE
Surfeit locus protein 4
Search

SURF4

0.96	Surfeit gene 4, like

0.49	GO:0007030	Golgi organization
0.47	GO:0010638	positive regulation of organelle organization
0.38	GO:0034498	early endosome to Golgi transport
0.37	GO:0032527	protein exit from endoplasmic reticulum
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER

0.34	GO:0005515	protein binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.51	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.39	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0000139	Golgi membrane
0.35	GO:0035577	azurophil granule membrane
0.34	GO:0030133	transport vesicle
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|Q7SZQ8|Q7SZQ8_DANRE
Prostaglandin E synthase 3 (Cytosolic)
Search

PTGES3

0.95	Cytosolic prostaglandin E synthase

0.73	GO:0046457	prostanoid biosynthetic process
0.72	GO:0006693	prostaglandin metabolic process
0.72	GO:1905323	telomerase holoenzyme complex assembly
0.68	GO:0051973	positive regulation of telomerase activity
0.68	GO:0007004	telomere maintenance via telomerase
0.68	GO:0060430	lung saccule development
0.67	GO:0042921	glucocorticoid receptor signaling pathway
0.63	GO:0043588	skin development
0.60	GO:0008283	cell proliferation
0.58	GO:0005978	glycogen biosynthetic process

0.69	GO:0070182	DNA polymerase binding
0.62	GO:0050220	prostaglandin-E synthase activity
0.49	GO:0003720	telomerase activity
0.47	GO:0051879	Hsp90 protein binding
0.44	GO:0051082	unfolded protein binding
0.44	GO:0002039	p53 binding
0.41	GO:0033142	progesterone receptor binding
0.40	GO:0003896	DNA primase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0030554	adenyl nucleotide binding

0.58	GO:0005654	nucleoplasm
0.58	GO:0005829	cytosol
0.50	GO:0005697	telomerase holoenzyme complex
0.43	GO:0005884	actin filament
0.43	GO:0070062	extracellular exosome
0.43	GO:0043025	neuronal cell body
0.42	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0043005	neuron projection
0.40	GO:0043234	protein complex
0.39	GO:0000781	chromosome, telomeric region

0.62	EC:5.3.99.3	GO:0050220
0.62	KEGG:R02265	GO:0050220

tr|Q7SZR0|Q7SZR0_DANRE
Ddc protein
Search

DDC

0.74	aromatic-L-amino-acid decarboxylase

0.60	GO:0006520	cellular amino acid metabolic process
0.47	GO:0009636	response to toxic substance
0.43	GO:0042416	dopamine biosynthetic process
0.42	GO:0007420	brain development
0.42	GO:0033076	isoquinoline alkaloid metabolic process
0.41	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle
0.41	GO:0052314	phytoalexin metabolic process
0.41	GO:0042427	serotonin biosynthetic process
0.41	GO:0071312	cellular response to alkaloid
0.40	GO:0010259	multicellular organism aging

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.48	GO:0019899	enzyme binding
0.38	GO:0019904	protein domain specific binding
0.38	GO:0016597	amino acid binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0008021	synaptic vesicle
0.39	GO:0043025	neuronal cell body
0.39	GO:0030424	axon
0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.68

EC:4.1.1

GO:0016831

tr|Q7SZR1|Q7SZR1_DANRE
Transducer of ERBB2, 1a
Search

TOB1

0.97	Transducer of ERBB2, 1

0.79	GO:0008285	negative regulation of cell proliferation
0.58	GO:0060212	negative regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.56	GO:0007184	SMAD protein import into nucleus
0.55	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.54	GO:0045668	negative regulation of osteoblast differentiation
0.53	GO:0030514	negative regulation of BMP signaling pathway
0.50	GO:0017148	negative regulation of translation
0.49	GO:0030509	BMP signaling pathway
0.49	GO:1903507	negative regulation of nucleic acid-templated transcription
0.42	GO:0060070	canonical Wnt signaling pathway

0.54	GO:0030971	receptor tyrosine kinase binding
0.53	GO:0003714	transcription corepressor activity
0.53	GO:0046332	SMAD binding
0.35	GO:0042809	vitamin D receptor binding
0.34	GO:0005070	SH3/SH2 adaptor activity

0.52	GO:0030014	CCR4-NOT complex
0.41	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm

tr|Q7SZR4|Q7SZR4_DANRE
Phosphoglycerate mutase
Search

PGAM1

0.49	Phosphoglycerate mutase

0.69	GO:0006757	ATP generation from ADP
0.67	GO:0006090	pyruvate metabolic process
0.66	GO:0016052	carbohydrate catabolic process
0.66	GO:0019362	pyridine nucleotide metabolic process
0.53	GO:0043456	regulation of pentose-phosphate shunt
0.45	GO:0019319	hexose biosynthetic process
0.44	GO:0006006	glucose metabolic process
0.42	GO:0045730	respiratory burst
0.42	GO:0006110	regulation of glycolytic process
0.37	GO:0006941	striated muscle contraction

0.80	GO:0004082	bisphosphoglycerate mutase activity
0.76	GO:0004619	phosphoglycerate mutase activity
0.40	GO:0019901	protein kinase binding
0.35	GO:0016787	hydrolase activity
0.32	GO:0048037	cofactor binding

0.46	GO:0043209	myelin sheath
0.44	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.35	GO:0097228	sperm principal piece
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.80

EC:5.4.2.4

GO:0004082

sp|Q7SZR5|SUMO1_DANRE
Small ubiquitin-related modifier 1
Search

SUMO1

0.76	Small ubiquitin-related modifier

0.79	GO:0016925	protein sumoylation
0.51	GO:1902260	negative regulation of delayed rectifier potassium channel activity
0.51	GO:0045759	negative regulation of action potential
0.51	GO:0071276	cellular response to cadmium ion
0.51	GO:0090204	protein localization to nuclear pore
0.50	GO:0030578	PML body organization
0.50	GO:1901896	positive regulation of calcium-transporting ATPase activity
0.49	GO:0060021	palate development
0.49	GO:0086004	regulation of cardiac muscle cell contraction
0.48	GO:0034605	cellular response to heat

0.61	GO:0008134	transcription factor binding
0.49	GO:0015459	potassium channel regulator activity
0.49	GO:0044388	small protein activating enzyme binding
0.48	GO:0031386	protein tag
0.47	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0008022	protein C-terminus binding
0.47	GO:0051427	hormone receptor binding
0.46	GO:0030674	protein binding, bridging
0.37	GO:0019789	SUMO transferase activity
0.33	GO:0003723	RNA binding

0.59	GO:0005634	nucleus
0.48	GO:0035770	ribonucleoprotein granule
0.46	GO:0001741	XY body
0.46	GO:0008076	voltage-gated potassium channel complex
0.43	GO:0070013	intracellular organelle lumen
0.43	GO:0012505	endomembrane system
0.41	GO:0031967	organelle envelope
0.41	GO:0031090	organelle membrane
0.40	GO:1902494	catalytic complex
0.38	GO:0000792	heterochromatin

0.32

GO:0016491

tr|Q7SZS0|Q7SZS0_DANRE
Serine/arginine-rich-splicing factor 10b
Search

SRSF10

0.92	FUS-interacting serine-arginine-rich protein 1

0.82	GO:0043484	regulation of RNA splicing
0.58	GO:0050684	regulation of mRNA processing
0.55	GO:0006376	mRNA splice site selection
0.47	GO:1903312	negative regulation of mRNA metabolic process
0.47	GO:0016482	cytosolic transport
0.46	GO:0045292	mRNA cis splicing, via spliceosome
0.44	GO:0010629	negative regulation of gene expression
0.36	GO:0000244	spliceosomal tri-snRNP complex assembly
0.36	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.35	GO:0051028	mRNA transport

0.58	GO:0003723	RNA binding
0.37	GO:0050733	RS domain binding
0.36	GO:0051082	unfolded protein binding

0.47	GO:0016607	nuclear speck
0.43	GO:0005829	cytosol
0.34	GO:0043679	axon terminus
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite

sp|Q7SZS1|SX21A_DANRE
Transcription factor Sox-21-A
Search

0.88	Transcription factor Sox-21-A

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.49	GO:0007275	multicellular organism development
0.47	GO:0030154	cell differentiation
0.47	GO:0009649	entrainment of circadian clock
0.44	GO:0030334	regulation of cell migration
0.44	GO:0007601	visual perception
0.44	GO:0042303	molting cycle
0.44	GO:0051960	regulation of nervous system development

0.55	GO:0003677	DNA binding
0.48	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.46	GO:0003682	chromatin binding
0.43	GO:0046982	protein heterodimerization activity
0.41	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0008013	beta-catenin binding

0.61	GO:0005634	nucleus
0.43	GO:0005667	transcription factor complex
0.38	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.34

EC:1.3.1.74

GO:0032440

tr|Q7SZW4|Q7SZW4_DANRE
SRY (sex determining region Y)-box 12
Search

0.84	SRY (Sex determining region Y)-box 4

0.59	GO:0061386	closure of optic fissure
0.57	GO:0045879	negative regulation of smoothened signaling pathway
0.46	GO:2001141	regulation of RNA biosynthetic process
0.46	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:0031018	endocrine pancreas development
0.45	GO:0010468	regulation of gene expression
0.41	GO:0002328	pro-B cell differentiation
0.41	GO:0003357	noradrenergic neuron differentiation
0.41	GO:0014009	glial cell proliferation
0.41	GO:0046826	negative regulation of protein export from nucleus

0.55	GO:0003677	DNA binding
0.48	GO:0003700	DNA binding transcription factor activity
0.40	GO:0001105	RNA polymerase II transcription coactivator activity
0.38	GO:0001067	regulatory region nucleic acid binding

0.61	GO:0005634	nucleus
0.36	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

tr|Q7SZW5|Q7SZW5_DANRE
Purine nucleoside phosphorylase
Search

0.47	Purine nucleoside phosphorylase

0.65	GO:0009116	nucleoside metabolic process
0.49	GO:0034418	urate biosynthetic process
0.48	GO:0070970	interleukin-2 secretion
0.48	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway
0.47	GO:0046638	positive regulation of alpha-beta T cell differentiation
0.46	GO:0042102	positive regulation of T cell proliferation
0.46	GO:0072526	pyridine-containing compound catabolic process
0.45	GO:1901658	glycosyl compound catabolic process
0.45	GO:0072523	purine-containing compound catabolic process
0.43	GO:0006955	immune response

0.76	GO:0004731	purine-nucleoside phosphorylase activity
0.49	GO:0002060	purine nucleobase binding
0.44	GO:0042301	phosphate ion binding
0.40	GO:0001882	nucleoside binding
0.37	GO:0008144	drug binding
0.36	GO:0047724	inosine nucleosidase activity
0.36	GO:0070635	nicotinamide riboside hydrolase activity

0.42	GO:0005829	cytosol
0.36	GO:0005856	cytoskeleton
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.34	GO:0005634	nucleus

0.76

EC:2.4.2.1

GO:0004731

tr|Q7SZW6|Q7SZW6_DANRE
Si:dkey-76p14.2 (Fragment)
Search

0.75	GO:0000278	mitotic cell cycle
0.67	GO:0051301	cell division

0.73	GO:0120103	centriolar subdistal appendage
0.64	GO:0005813	centrosome
0.57	GO:0005829	cytosol

tr|Q7SZW7|Q7SZW7_DANRE
Serine incorporator 1
Search

SERINC1

0.90	Tumor differentially expressed 2

0.84	GO:0006658	phosphatidylserine metabolic process
0.79	GO:0006665	sphingolipid metabolic process
0.50	GO:0015825	L-serine transport
0.42	GO:0009597	detection of virus
0.42	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.40	GO:1904219	positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity
0.40	GO:1904222	positive regulation of serine C-palmitoyltransferase activity
0.40	GO:0045087	innate immune response
0.39	GO:0051607	defense response to virus
0.37	GO:0044091	membrane biogenesis

0.50	GO:0015194	L-serine transmembrane transporter activity
0.38	GO:0030674	protein binding, bridging
0.36	GO:0019899	enzyme binding

0.69	GO:0005789	endoplasmic reticulum membrane
0.42	GO:0005886	plasma membrane
0.38	GO:0005794	Golgi apparatus
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

tr|Q7SZW8|Q7SZW8_DANRE
Heat shock transcription factor 2
Search

HSF2

0.96	LOW QUALITY PROTEIN: heat shock factor protein 2

0.65	GO:0006357	regulation of transcription by RNA polymerase II
0.49	GO:0006366	transcription by RNA polymerase II
0.49	GO:0045893	positive regulation of transcription, DNA-templated
0.48	GO:0007283	spermatogenesis
0.45	GO:0002088	lens development in camera-type eye
0.43	GO:0009408	response to heat
0.37	GO:0070207	protein homotrimerization
0.36	GO:1900365	positive regulation of mRNA polyadenylation
0.36	GO:0051457	maintenance of protein location in nucleus
0.36	GO:0043497	regulation of protein heterodimerization activity

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.47	GO:0042803	protein homodimerization activity
0.36	GO:0032183	SUMO binding
0.36	GO:1990841	promoter-specific chromatin binding
0.35	GO:0043621	protein self-association
0.35	GO:0031490	chromatin DNA binding

0.61	GO:0005634	nucleus
0.47	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.37	GO:0005737	cytoplasm
0.35	GO:0035770	ribonucleoprotein granule
0.34	GO:0015630	microtubule cytoskeleton
0.34	GO:0005694	chromosome
0.33	GO:0043234	protein complex

tr|Q7SZX9|Q7SZX9_DANRE
FLJ10613-like
Search

GNL3L

0.49	G protein nucleolar 3 like

0.48	GO:1904816	positive regulation of protein localization to chromosome, telomeric region
0.47	GO:0033233	regulation of protein sumoylation
0.47	GO:0042254	ribosome biogenesis
0.46	GO:0032204	regulation of telomere maintenance
0.44	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II
0.43	GO:0017145	stem cell division
0.43	GO:0016072	rRNA metabolic process
0.43	GO:0019827	stem cell population maintenance
0.43	GO:0032846	positive regulation of homeostatic process
0.42	GO:2001252	positive regulation of chromosome organization

0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0003924	GTPase activity
0.42	GO:0048027	mRNA 5'-UTR binding
0.34	GO:0005515	protein binding

0.47	GO:0005730	nucleolus
0.42	GO:0016604	nuclear body
0.40	GO:0005697	telomerase holoenzyme complex
0.37	GO:0005829	cytosol
0.34	GO:0005615	extracellular space
0.34	GO:0030687	preribosome, large subunit precursor
0.34	GO:0055044	symplast
0.33	GO:0005911	cell-cell junction
0.30	GO:0031224	intrinsic component of membrane

tr|Q7SZY5|Q7SZY5_DANRE
RIMS-binding protein 2 (Fragment)
Search

0.64	RIMS binding protein 2

0.78

GO:0010923

negative regulation of phosphatase activity

0.43	GO:0045202	synapse
0.42	GO:0030054	cell junction
0.37	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q7SZY8|Q7SZY8_DANRE
Glyoxylate reductase/hydroxypyruvate reductase a
Search

GRHPR

0.89	Glyoxylate and hydroxypyruvate reductase

0.55	GO:0007588	excretion
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0046487	glyoxylate metabolic process
0.49	GO:0051259	protein oligomerization
0.36	GO:0043648	dicarboxylic acid metabolic process
0.33	GO:0000103	sulfate assimilation
0.33	GO:0001522	pseudouridine synthesis
0.33	GO:0042254	ribosome biogenesis
0.32	GO:0016310	phosphorylation

0.68	GO:0051287	NAD binding
0.66	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.51	GO:0070402	NADPH binding
0.50	GO:0042803	protein homodimerization activity
0.37	GO:0043177	organic acid binding
0.33	GO:0004020	adenylylsulfate kinase activity
0.33	GO:0004781	sulfate adenylyltransferase (ATP) activity
0.32	GO:0005524	ATP binding

0.44	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.35	GO:0031907	microbody lumen
0.34	GO:0044439	peroxisomal part
0.34	GO:0031429	box H/ACA snoRNP complex

0.66

EC:1.1.1

GO:0016616

tr|Q7SZZ0|Q7SZZ0_DANRE
Novel protein
Search

tr|Q7SZZ2|Q7SZZ2_DANRE
Si:ch211-237l4.6
Search

tr|Q7SZZ5|Q7SZZ5_DANRE
Vesicle-associated membrane protein 2
Search

VAMP2

0.92	Chain A, Neuronal Synaptic Fusion Complex

0.69	GO:0016192	vesicle-mediated transport
0.55	GO:0061951	establishment of protein localization to plasma membrane
0.54	GO:0090174	organelle membrane fusion
0.53	GO:0016050	vesicle organization
0.52	GO:1903530	regulation of secretion by cell
0.51	GO:0001921	positive regulation of receptor recycling
0.51	GO:0032940	secretion by cell
0.50	GO:0034446	substrate adhesion-dependent cell spreading
0.50	GO:0071310	cellular response to organic substance
0.49	GO:1903540	establishment of protein localization to postsynaptic membrane

0.53	GO:0000149	SNARE binding
0.48	GO:0005484	SNAP receptor activity
0.45	GO:0005516	calmodulin binding
0.44	GO:0005543	phospholipid binding
0.39	GO:0008022	protein C-terminus binding
0.38	GO:0048306	calcium-dependent protein binding
0.37	GO:0044325	ion channel binding
0.37	GO:0017022	myosin binding
0.36	GO:0032403	protein complex binding
0.36	GO:0042802	identical protein binding

0.58	GO:0031201	SNARE complex
0.54	GO:0030141	secretory granule
0.52	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0055037	recycling endosome
0.48	GO:0045335	phagocytic vesicle
0.48	GO:0030672	synaptic vesicle membrane
0.48	GO:0030136	clathrin-coated vesicle
0.47	GO:0009986	cell surface
0.45	GO:0005802	trans-Golgi network
0.45	GO:0000322	storage vacuole

0.34

EC:1.13.11

GO:0016702

tr|Q7SZZ6|Q7SZZ6_DANRE
Actinodin3
Search

0.57	DNA polymerase III subunits gamma and tau domain-containing protein

0.65

GO:0007018

microtubule-based movement

0.42

GO:0008080

N-acetyltransferase activity

0.73

GO:0005868

cytoplasmic dynein complex

0.42

GO:0008080

tr|Q7SZZ7|Q7SZZ7_DANRE
Adaptor-related protein complex 4, mu 1 subunit
Search

AP4M1

0.97	LOW QUALITY PROTEIN: AP-4 complex subunit mu-1

0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.53	GO:0061462	protein localization to lysosome
0.52	GO:0007041	lysosomal transport
0.51	GO:0072666	establishment of protein localization to vacuole
0.50	GO:0016482	cytosolic transport
0.49	GO:0016197	endosomal transport
0.41	GO:1903361	protein localization to basolateral plasma membrane
0.34	GO:0015976	carbon utilization
0.33	GO:0043547	positive regulation of GTPase activity

0.49	GO:0019904	protein domain specific binding
0.34	GO:0004089	carbonate dehydratase activity
0.33	GO:0005096	GTPase activator activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.32	GO:0008289	lipid binding
0.32	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0005216	ion channel activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding

0.79	GO:0030131	clathrin adaptor complex
0.54	GO:0030124	AP-4 adaptor complex
0.51	GO:0005802	trans-Golgi network
0.46	GO:0005829	cytosol
0.39	GO:0005769	early endosome
0.36	GO:0070062	extracellular exosome
0.35	GO:0031904	endosome lumen
0.35	GO:0051285	cell cortex of cell tip
0.34	GO:0005905	clathrin-coated pit
0.34	GO:0098588	bounding membrane of organelle

0.34

EC:4.2.1.1

GO:0004089

sp|Q7T005|RFIP3_DANRE
Rab11 family-interacting protein 3
Search

0.55	Rab11 family-interacting protein 3

0.83	GO:0032456	endocytic recycling
0.71	GO:0000910	cytokinesis
0.51	GO:0032465	regulation of cytokinesis
0.41	GO:0070164	negative regulation of adiponectin secretion
0.40	GO:0048592	eye morphogenesis
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.85	GO:0030306	ADP-ribosylation factor binding
0.80	GO:0017137	Rab GTPase binding
0.52	GO:0005509	calcium ion binding
0.50	GO:0042803	protein homodimerization activity
0.40	GO:0051959	dynein light intermediate chain binding
0.35	GO:0003700	DNA binding transcription factor activity

0.54	GO:0032154	cleavage furrow
0.53	GO:0030496	midbody
0.53	GO:0055037	recycling endosome
0.50	GO:0005813	centrosome
0.49	GO:0010008	endosome membrane
0.40	GO:0045171	intercellular bridge
0.37	GO:0030139	endocytic vesicle
0.37	GO:0005654	nucleoplasm

sp|Q7T006|TELO2_DANRE
Telomere length regulation protein TEL2 homolog
Search

TELO2

0.96	Telomere maintenance 2

0.85	GO:1904515	positive regulation of TORC2 signaling
0.78	GO:1904263	positive regulation of TORC1 signaling
0.74	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.74	GO:0050821	protein stabilization

0.81	GO:0051879	Hsp90 protein binding
0.73	GO:0019901	protein kinase binding
0.71	GO:0032947	protein complex scaffold activity
0.70	GO:0032403	protein complex binding

0.77	GO:0031931	TORC1 complex
0.76	GO:0031932	TORC2 complex
0.75	GO:0034399	nuclear periphery
0.73	GO:0016604	nuclear body
0.64	GO:0005829	cytosol
0.47	GO:0000781	chromosome, telomeric region
0.30	GO:0031224	intrinsic component of membrane

tr|Q7T009|Q7T009_DANRE
DCTP pyrophosphatase 1
Search

DCTPP1

0.96	dCTP pyrophosphatase 1

0.78	GO:0009143	nucleoside triphosphate catabolic process
0.51	GO:0046065	dCTP metabolic process
0.49	GO:0009223	pyrimidine deoxyribonucleotide catabolic process
0.48	GO:0042262	DNA protection
0.46	GO:0051289	protein homotetramerization
0.35	GO:0046075	dTTP metabolic process

0.75	GO:0047429	nucleoside-triphosphate diphosphatase activity
0.50	GO:0032556	pyrimidine deoxyribonucleotide binding
0.49	GO:0046872	metal ion binding
0.44	GO:0042802	identical protein binding
0.32	GO:0003723	RNA binding

0.42	GO:0005829	cytosol
0.40	GO:0005634	nucleus
0.40	GO:0005739	mitochondrion

0.75

EC:3.6.1.19

GO:0047429

sp|Q7T010|GATB_DANRE
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial
Search

GATB

0.72	Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial

0.74	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation
0.71	GO:0032543	mitochondrial translation
0.34	GO:0006425	glutaminyl-tRNA aminoacylation

0.71	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor
0.58	GO:0140101	catalytic activity, acting on a tRNA
0.50	GO:0032559	adenyl ribonucleotide binding
0.49	GO:0008144	drug binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0016740	transferase activity
0.33	GO:0008135	translation factor activity, RNA binding

0.69	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex
0.55	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.71

EC:6.3.5

GO:0016884

tr|Q7T011|Q7T011_DANRE
Transforming growth factor, alpha
Search

0.97	LOW QUALITY PROTEIN: protransforming growth factor alpha

0.56	GO:0007173	epidermal growth factor receptor signaling pathway
0.53	GO:0072574	hepatocyte proliferation
0.53	GO:0008284	positive regulation of cell proliferation
0.53	GO:0001934	positive regulation of protein phosphorylation
0.51	GO:0050730	regulation of peptidyl-tyrosine phosphorylation
0.51	GO:0061377	mammary gland lobule development
0.49	GO:0001525	angiogenesis
0.48	GO:0043405	regulation of MAP kinase activity
0.47	GO:0033674	positive regulation of kinase activity
0.47	GO:1902533	positive regulation of intracellular signal transduction

0.57	GO:0005154	epidermal growth factor receptor binding
0.47	GO:0008083	growth factor activity
0.33	GO:0017154	semaphorin receptor activity
0.33	GO:0005089	Rho guanyl-nucleotide exchange factor activity

0.46	GO:0005615	extracellular space
0.43	GO:0005887	integral component of plasma membrane
0.37	GO:0016323	basolateral plasma membrane
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0009986	cell surface
0.36	GO:0031410	cytoplasmic vesicle
0.35	GO:0005634	nucleus
0.35	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.34	GO:0012506	vesicle membrane
0.34	GO:0000139	Golgi membrane

sp|Q7T012|HDHD3_DANRE
Haloacid dehalogenase-like hydrolase domain-containing protein 3
Search

HDHD3

0.94	Haloacid dehalogenase like hydrolase domain containing 3

0.36

GO:0016311

dephosphorylation

0.51	GO:0016787	hydrolase activity
0.34	GO:0005515	protein binding

0.45

GO:0005739

mitochondrion

0.51

GO:0016787

sp|Q7T019|DZIP1_DANRE
Zinc finger protein Dzip1
Search

DZIP1

0.73	Zinc finger protein Dzip1

0.48	GO:2000223	regulation of BMP signaling pathway involved in heart jogging
0.47	GO:0021984	adenohypophysis development
0.47	GO:0031290	retinal ganglion cell axon guidance
0.46	GO:0006607	NLS-bearing protein import into nucleus
0.46	GO:0001947	heart looping
0.46	GO:0008589	regulation of smoothened signaling pathway
0.46	GO:0035082	axoneme assembly
0.44	GO:0001568	blood vessel development
0.35	GO:0032880	regulation of protein localization
0.34	GO:0097359	UDP-glucosylation

0.51	GO:0003676	nucleic acid binding
0.38	GO:0046872	metal ion binding
0.34	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity
0.32	GO:0005515	protein binding

0.47	GO:0036064	ciliary basal body
0.47	GO:0005814	centriole
0.45	GO:0097730	non-motile cilium
0.39	GO:0005634	nucleus
0.33	GO:0097539	ciliary transition fiber
0.32	GO:0005829	cytosol
0.32	GO:0043233	organelle lumen
0.30	GO:0016020	membrane

0.34

GO:0003980

sp|Q7T047|CX32_DANRE
Gap junction Cx32.2 protein
Search

0.60	Gap junction protein (Fragment)

0.60	GO:0007154	cell communication
0.57	GO:0007601	visual perception
0.46	GO:0072359	circulatory system development
0.44	GO:0055085	transmembrane transport
0.42	GO:0048050	post-embryonic eye morphogenesis
0.42	GO:0031444	slow-twitch skeletal muscle fiber contraction
0.41	GO:0060415	muscle tissue morphogenesis
0.41	GO:0008016	regulation of heart contraction
0.40	GO:0014706	striated muscle tissue development
0.34	GO:0048265	response to pain

0.63	GO:0005243	gap junction channel activity
0.33	GO:0005515	protein binding

0.83	GO:0005922	connexin complex
0.34	GO:0005887	integral component of plasma membrane

sp|Q7T070|RHBG_DANRE
Ammonium transporter Rh type B
Search

RHBG

0.83	Rhesus blood group-associated glycoprotein b

0.77	GO:0072488	ammonium transmembrane transport
0.61	GO:0070634	transepithelial ammonium transport
0.51	GO:0048878	chemical homeostasis
0.47	GO:0015695	organic cation transport
0.45	GO:0019725	cellular homeostasis
0.34	GO:0015837	amine transport
0.34	GO:0015840	urea transport
0.34	GO:0030855	epithelial cell differentiation

0.77	GO:0008519	ammonium transmembrane transporter activity
0.59	GO:0030506	ankyrin binding
0.46	GO:0042802	identical protein binding

0.58	GO:0016323	basolateral plasma membrane
0.52	GO:0016324	apical plasma membrane
0.50	GO:0005887	integral component of plasma membrane
0.49	GO:0014731	spectrin-associated cytoskeleton
0.45	GO:0046658	anchored component of plasma membrane
0.44	GO:0031410	cytoplasmic vesicle
0.43	GO:0012506	vesicle membrane
0.38	GO:0044446	intracellular organelle part
0.35	GO:0016327	apicolateral plasma membrane
0.34	GO:0070062	extracellular exosome

tr|Q7T0K2|Q7T0K2_DANRE
Baculoviral IAP repeat-containing 2
Search

BIRC2

0.88	Inhibitor of apoptosis protein (Fragment)

0.74	GO:0042981	regulation of apoptotic process
0.41	GO:0060546	negative regulation of necroptotic process
0.41	GO:0097340	inhibition of cysteine-type endopeptidase activity
0.40	GO:0034121	regulation of toll-like receptor signaling pathway
0.40	GO:0090307	mitotic spindle assembly
0.39	GO:0006915	apoptotic process
0.38	GO:0016567	protein ubiquitination

0.41	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.38	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0046872	metal ion binding

0.36	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm

0.38

GO:0004842

tr|Q7T0K5|Q7T0K5_DANRE
Mage
Search

0.85	Magphinin delta

0.59	GO:0030308	negative regulation of cell growth
0.57	GO:0072711	cellular response to hydroxyurea
0.54	GO:0034644	cellular response to UV
0.54	GO:0031398	positive regulation of protein ubiquitination
0.49	GO:0070534	protein K63-linked ubiquitination
0.47	GO:0042147	retrograde transport, endosome to Golgi
0.47	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.45	GO:0006281	DNA repair
0.44	GO:0051127	positive regulation of actin nucleation
0.44	GO:0042752	regulation of circadian rhythm

0.48	GO:0005515	protein binding
0.44	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0003723	RNA binding

0.52	GO:0030915	Smc5-Smc6 complex
0.50	GO:0005634	nucleus
0.47	GO:0030904	retromer complex
0.45	GO:0005768	endosome
0.43	GO:0005829	cytosol
0.41	GO:0000781	chromosome, telomeric region
0.38	GO:0043233	organelle lumen
0.36	GO:0005887	integral component of plasma membrane

0.44

GO:0004842

tr|Q7T119|Q7T119_DANRE
Galectin
Search

0.61

Galectin

0.39	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.38	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation
0.38	GO:2001181	positive regulation of interleukin-10 secretion
0.38	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity
0.38	GO:0043301	negative regulation of leukocyte degranulation
0.38	GO:0045591	positive regulation of regulatory T cell differentiation
0.38	GO:1902713	regulation of interferon-gamma secretion
0.38	GO:0070241	positive regulation of activated T cell autonomous cell death
0.38	GO:2001190	positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
0.38	GO:2000778	positive regulation of interleukin-6 secretion

0.70	GO:0030246	carbohydrate binding
0.36	GO:0004672	protein kinase activity
0.35	GO:0019899	enzyme binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008144	drug binding
0.34	GO:0046872	metal ion binding
0.34	GO:0043539	protein serine/threonine kinase activator activity
0.33	GO:0005102	receptor binding

0.38	GO:0005829	cytosol
0.38	GO:0005615	extracellular space
0.35	GO:0005634	nucleus
0.34	GO:1903561	extracellular vesicle
0.32	GO:0019028	viral capsid
0.30	GO:0016021	integral component of membrane

0.34

EC:1.97.1

GO:0051353

tr|Q7T133|Q7T133_DANRE
Novel protein
Search

PCP4L1

0.97	Brain-specific polypeptide PEP-19

0.40	GO:0050982	detection of mechanical stimulus
0.39	GO:0007339	binding of sperm to zona pellucida
0.38	GO:0070588	calcium ion transmembrane transport
0.37	GO:0040008	regulation of growth
0.36	GO:0006468	protein phosphorylation

0.74	GO:0005516	calmodulin binding
0.39	GO:0005262	calcium channel activity
0.36	GO:0004672	protein kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

sp|Q7T141|PI15A_DANRE
Peptidase inhibitor 15-A
Search

PI15

0.97	Peptidase inhibitor 15-A

0.46	GO:0060325	face morphogenesis
0.43	GO:0030198	extracellular matrix organization
0.40	GO:0007275	multicellular organism development
0.38	GO:0010466	negative regulation of peptidase activity
0.36	GO:0060021	palate development
0.36	GO:1904888	cranial skeletal system development
0.36	GO:0061448	connective tissue development
0.36	GO:0048729	tissue morphogenesis
0.34	GO:0043312	neutrophil degranulation
0.33	GO:0006508	proteolysis

0.43	GO:0008201	heparin binding
0.38	GO:0030414	peptidase inhibitor activity
0.33	GO:0008233	peptidase activity

0.65	GO:0005576	extracellular region
0.41	GO:0030133	transport vesicle
0.34	GO:1904813	ficolin-1-rich granule lumen
0.34	GO:0034774	secretory granule lumen
0.30	GO:0016020	membrane

0.33

GO:0008233

tr|Q7T162|Q7T162_DANRE
F-box and leucine-rich repeat protein 3a
Search

FBXL3

0.95	F-box and leucine-rich repeat protein 3

0.86	GO:0043153	entrainment of circadian clock by photoperiod
0.85	GO:0031648	protein destabilization
0.84	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.73	GO:0016567	protein ubiquitination

0.74

GO:0004842

ubiquitin-protein transferase activity

0.83	GO:0019005	SCF ubiquitin ligase complex
0.77	GO:0016604	nuclear body
0.68	GO:0005829	cytosol

0.74

GO:0004842

sp|Q7T163|KDIS_DANRE
Kinase D-interacting substrate of 220 kDa
Search

0.80	Kinase D-interacting substrate of

0.53	GO:0016310	phosphorylation
0.48	GO:0048813	dendrite morphogenesis
0.46	GO:0038180	nerve growth factor signaling pathway
0.44	GO:0001701	in utero embryonic development
0.42	GO:0045859	regulation of protein kinase activity
0.36	GO:0010976	positive regulation of neuron projection development
0.34	GO:0043410	positive regulation of MAPK cascade
0.34	GO:0033674	positive regulation of kinase activity

0.55	GO:0016301	kinase activity
0.44	GO:0030165	PDZ domain binding
0.43	GO:0019887	protein kinase regulator activity
0.34	GO:0019901	protein kinase binding

0.38	GO:0005770	late endosome
0.35	GO:0010008	endosome membrane
0.35	GO:0005829	cytosol
0.34	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

tr|Q7T168|Q7T168_DANRE
Ankyrin repeat domain 33ba (Fragment)
Search

ANKRD33B

0.96	ankyrin repeat domain-containing protein 33B

0.76	GO:2000678	negative regulation of transcription regulatory region DNA binding
0.75	GO:0035914	skeletal muscle cell differentiation
0.68	GO:0000122	negative regulation of transcription by RNA polymerase II

0.45

GO:0003677

DNA binding

0.61	GO:0005829	cytosol
0.55	GO:0005634	nucleus

tr|Q7T171|Q7T171_DANRE
Si:rp71-1f1.5
Search

0.31	N-hydroxyarylamine O-acetyltransferase

0.33	GO:0030150	protein import into mitochondrial matrix
0.30	GO:0008152	metabolic process

0.67	GO:0016407	acetyltransferase activity
0.41	GO:0016410	N-acyltransferase activity
0.37	GO:0008374	O-acyltransferase activity

0.33	GO:0005744	mitochondrial inner membrane presequence translocase complex
0.30	GO:0031224	intrinsic component of membrane

0.67

GO:0016407

tr|Q7T172|Q7T172_DANRE
Si:rp71-1f1.4
Search

0.27	N-hydroxyarylamine O-acetyltransferase

0.33	GO:0030150	protein import into mitochondrial matrix
0.30	GO:0008152	metabolic process

0.67	GO:0016407	acetyltransferase activity
0.42	GO:0016410	N-acyltransferase activity
0.38	GO:0008374	O-acyltransferase activity

0.33	GO:0005744	mitochondrial inner membrane presequence translocase complex
0.30	GO:0031224	intrinsic component of membrane

0.67

GO:0016407

tr|Q7T174|Q7T174_DANRE
Spermidine/spermine N1-acetyl transferase 1
Search

SAT1

0.96	Diamine acetyltransferase 1

0.53	GO:0001525	angiogenesis
0.50	GO:0032918	spermidine acetylation
0.50	GO:0046208	spermine catabolic process
0.48	GO:0042127	regulation of cell proliferation
0.42	GO:0009447	putrescine catabolic process
0.37	GO:0032919	spermine acetylation
0.34	GO:0006596	polyamine biosynthetic process

0.85	GO:0004145	diamine N-acetyltransferase activity
0.51	GO:0019809	spermidine binding
0.49	GO:0042802	identical protein binding

0.41	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:2.3.1.57

GO:0004145

tr|Q7T177|Q7T177_DANRE
Zinc finger protein 668
Search

0.49	Zinc finger protein 668

0.45	GO:1903506	regulation of nucleic acid-templated transcription
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:0010468	regulation of gene expression
0.44	GO:1902679	negative regulation of RNA biosynthetic process
0.34	GO:0006351	transcription, DNA-templated
0.33	GO:0006260	DNA replication
0.32	GO:0055114	oxidation-reduction process
0.32	GO:0032259	methylation

0.51	GO:0003676	nucleic acid binding
0.47	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.41	GO:0046872	metal ion binding
0.32	GO:0008168	methyltransferase activity

0.37	GO:0005622	intracellular
0.36	GO:0043227	membrane-bounded organelle

0.32

GO:0008168

tr|Q7T181|Q7T181_DANRE
Inhibitor of growth protein
Search

ING5

0.70	Inhibitor of growth protein 5

0.78	GO:0008285	negative regulation of cell proliferation
0.78	GO:0016573	histone acetylation
0.67	GO:0043065	positive regulation of apoptotic process
0.49	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.47	GO:0045926	negative regulation of growth
0.47	GO:0007050	cell cycle arrest
0.45	GO:0006915	apoptotic process
0.43	GO:2001233	regulation of apoptotic signaling pathway
0.43	GO:0045892	negative regulation of transcription, DNA-templated
0.42	GO:0006260	DNA replication

0.69	GO:0140034	methylation-dependent protein binding
0.66	GO:0042393	histone binding
0.53	GO:0046872	metal ion binding
0.46	GO:0003713	transcription coactivator activity
0.42	GO:0003682	chromatin binding
0.33	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors

0.70	GO:0070776	MOZ/MORF histone acetyltransferase complex
0.45	GO:0045111	intermediate filament cytoskeleton
0.42	GO:0005829	cytosol

0.33

EC:1.1

GO:0016614

tr|Q7T1A1|Q7T1A1_DANRE
Dopamine D2c receptor
Search

DRD2

0.93	Dopamine receptor type 2

0.85	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway
0.61	GO:0051967	negative regulation of synaptic transmission, glutamatergic
0.60	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway
0.60	GO:0048148	behavioral response to cocaine
0.59	GO:0014059	regulation of dopamine secretion
0.59	GO:0048149	behavioral response to ethanol
0.58	GO:0051944	positive regulation of catecholamine uptake involved in synaptic transmission
0.58	GO:1900166	regulation of glial cell-derived neurotrophic factor secretion
0.58	GO:0060160	negative regulation of dopamine receptor signaling pathway
0.58	GO:0035815	positive regulation of renal sodium excretion

0.85	GO:0004952	dopamine neurotransmitter receptor activity
0.60	GO:0035240	dopamine binding
0.49	GO:0042802	identical protein binding
0.48	GO:0004935	adrenergic receptor activity
0.39	GO:0035255	ionotropic glutamate receptor binding
0.37	GO:0046982	protein heterodimerization activity
0.35	GO:0015459	potassium channel regulator activity

0.66	GO:0005887	integral component of plasma membrane
0.54	GO:0060170	ciliary membrane
0.53	GO:0097458	neuron part
0.53	GO:0097730	non-motile cilium
0.49	GO:0099501	exocytic vesicle membrane
0.45	GO:0044456	synapse part
0.39	GO:0016328	lateral plasma membrane
0.39	GO:0036126	sperm flagellum
0.38	GO:0001669	acrosomal vesicle
0.38	GO:0032279	asymmetric synapse

tr|Q7T1B0|Q7T1B0_DANRE
Embryonic globin beta e2
Search

0.74	Embryonic beta-type globin

0.79	GO:0015671	oxygen transport
0.35	GO:0030097	hemopoiesis
0.34	GO:0001666	response to hypoxia

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding

0.82

GO:0005833

hemoglobin complex

tr|Q7T1D7|Q7T1D7_DANRE
Dimethylaniline monooxygenase [N-oxide-forming]
Search

FMO5

0.62	Flavin-containing monooxygenase

0.52	GO:0055114	oxidation-reduction process
0.37	GO:0072592	oxygen metabolic process
0.35	GO:0006805	xenobiotic metabolic process
0.35	GO:0009404	toxin metabolic process
0.34	GO:0006739	NADP metabolic process
0.34	GO:0006308	DNA catabolic process
0.33	GO:0042737	drug catabolic process
0.33	GO:0006082	organic acid metabolic process

0.77	GO:0004499	N,N-dimethylaniline monooxygenase activity
0.69	GO:0050661	NADP binding
0.65	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0004536	deoxyribonuclease activity

0.44	GO:0005783	endoplasmic reticulum
0.43	GO:0005829	cytosol
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.36	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.77

EC:1.14.13.8

GO:0004499

tr|Q7T1D8|Q7T1D8_DANRE
Phb
Search

PHB

0.85	Mitochondrial prohibitin

0.54	GO:0045917	positive regulation of complement activation
0.53	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway
0.53	GO:0050847	progesterone receptor signaling pathway
0.53	GO:0010944	negative regulation of transcription by competitive promoter binding
0.53	GO:0060766	negative regulation of androgen receptor signaling pathway
0.52	GO:0071354	cellular response to interleukin-6
0.52	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
0.51	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.50	GO:0042177	negative regulation of protein catabolic process
0.50	GO:0030308	negative regulation of cell growth

0.55	GO:0001850	complement component C3a binding
0.54	GO:0001851	complement component C3b binding
0.54	GO:0031871	proteinase activated receptor binding
0.51	GO:0042826	histone deacetylase binding
0.50	GO:0008022	protein C-terminus binding
0.47	GO:0044212	transcription regulatory region DNA binding
0.46	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding

0.49	GO:0043209	myelin sheath
0.49	GO:0005769	early endosome
0.49	GO:0009986	cell surface
0.45	GO:0005654	nucleoplasm
0.44	GO:0005887	integral component of plasma membrane
0.43	GO:0031966	mitochondrial membrane
0.43	GO:0019866	organelle inner membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:0031312	extrinsic component of organelle membrane
0.35	GO:0031968	organelle outer membrane

sp|Q7T1H5|DND1_DANRE
Dead end protein 1
Search

0.91	S dead end protein mRNA

0.56	GO:0060965	negative regulation of gene silencing by miRNA
0.50	GO:0007281	germ cell development
0.47	GO:0008354	germ cell migration
0.47	GO:0048255	mRNA stabilization
0.46	GO:0060047	heart contraction
0.45	GO:0007275	multicellular organism development
0.44	GO:2000145	regulation of cell motility

0.59	GO:0003723	RNA binding
0.35	GO:0005515	protein binding

0.47	GO:0043073	germ cell nucleus
0.46	GO:0043186	P granule

tr|Q7T1J9|Q7T1J9_DANRE
Ribosomal protein S10
Search

RPS10

0.70	Ribosomal protein S10

0.56	GO:0000028	ribosomal small subunit assembly
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.35	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.34	GO:0006413	translational initiation
0.34	GO:0006364	rRNA processing

0.46	GO:0003735	structural constituent of ribosome
0.44	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.34	GO:0016787	hydrolase activity
0.34	GO:0005509	calcium ion binding

0.59	GO:0005840	ribosome
0.53	GO:0044445	cytosolic part
0.46	GO:0005730	nucleolus
0.37	GO:0031012	extracellular matrix
0.37	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome
0.34	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.34

GO:0016787

tr|Q7T1K0|Q7T1K0_DANRE
Ribosomal protein L17
Search

RPL17

0.70	W-linked ribosomal protein L17

0.59	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.36	GO:1990928	response to amino acid starvation
0.35	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.35	GO:0034198	cellular response to amino acid starvation
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.62	GO:0003735	structural constituent of ribosome
0.35	GO:0070180	large ribosomal subunit rRNA binding
0.34	GO:0005515	protein binding

0.69	GO:0015934	large ribosomal subunit
0.36	GO:0022626	cytosolic ribosome
0.35	GO:0031672	A band
0.35	GO:0005844	polysome
0.34	GO:0005634	nucleus

tr|Q7T1K1|Q7T1K1_DANRE
TRAF4 protein
Search

TRAF4

0.96	TNF receptor-associated factor 4

0.84	GO:0007250	activation of NF-kappaB-inducing kinase activity
0.81	GO:0046330	positive regulation of JNK cascade
0.72	GO:0042981	regulation of apoptotic process
0.58	GO:0090073	positive regulation of protein homodimerization activity
0.56	GO:0007585	respiratory gaseous exchange
0.55	GO:0030323	respiratory tube development
0.36	GO:0006915	apoptotic process
0.36	GO:0036211	protein modification process
0.35	GO:0044267	cellular protein metabolic process
0.34	GO:0016310	phosphorylation

0.62	GO:0008270	zinc ion binding
0.57	GO:0031996	thioesterase binding
0.56	GO:0050699	WW domain binding
0.54	GO:0005164	tumor necrosis factor receptor binding
0.52	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0019901	protein kinase binding
0.50	GO:0042802	identical protein binding
0.36	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0003676	nucleic acid binding
0.35	GO:0004672	protein kinase activity

0.44	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.37	GO:0005923	bicellular tight junction
0.35	GO:0005856	cytoskeleton
0.33	GO:0005886	plasma membrane
0.32	GO:0030529	intracellular ribonucleoprotein complex

0.36

GO:0004842

tr|Q7T1K2|Q7T1K2_DANRE
TRAF4 protein
Search

TRAF4

0.96	TNF receptor-associated factor 4

0.84	GO:0007250	activation of NF-kappaB-inducing kinase activity
0.80	GO:0046330	positive regulation of JNK cascade
0.72	GO:0042981	regulation of apoptotic process
0.59	GO:0090073	positive regulation of protein homodimerization activity
0.58	GO:0007585	respiratory gaseous exchange
0.56	GO:0030323	respiratory tube development
0.37	GO:0006915	apoptotic process

0.62	GO:0008270	zinc ion binding
0.59	GO:0031996	thioesterase binding
0.58	GO:0050699	WW domain binding
0.55	GO:0005164	tumor necrosis factor receptor binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0019901	protein kinase binding
0.51	GO:0042802	identical protein binding
0.33	GO:0003677	DNA binding
0.32	GO:0016740	transferase activity

0.45	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.37	GO:0005923	bicellular tight junction
0.35	GO:0005856	cytoskeleton
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.32

GO:0016740

tr|Q7T1S3|Q7T1S3_DANRE
Transcription factor YY1
Search

0.89	transcriptional repressor protein YY1

0.44	GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II
0.44	GO:0032688	negative regulation of interferon-beta production
0.44	GO:0048513	animal organ development
0.44	GO:0010225	response to UV-C
0.43	GO:0010628	positive regulation of gene expression
0.43	GO:0034644	cellular response to UV
0.42	GO:0009952	anterior/posterior pattern specification
0.42	GO:0007283	spermatogenesis
0.41	GO:0000724	double-strand break repair via homologous recombination
0.41	GO:0060322	head development

0.51	GO:0003676	nucleic acid binding
0.43	GO:0046332	SMAD binding
0.43	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0042826	histone deacetylase binding
0.33	GO:0003714	transcription corepressor activity
0.32	GO:0003713	transcription coactivator activity
0.32	GO:0003682	chromatin binding
0.32	GO:0046872	metal ion binding

0.42	GO:0031519	PcG protein complex
0.41	GO:0031011	Ino80 complex
0.40	GO:0005667	transcription factor complex
0.34	GO:0016363	nuclear matrix
0.33	GO:0005654	nucleoplasm
0.32	GO:0005737	cytoplasm

tr|Q7T289|Q7T289_DANRE
Amino-terminal enhancer of split
Search

AES

0.97	Amino-terminal enhancer of split

0.66	GO:2000210	positive regulation of anoikis
0.61	GO:0070555	response to interleukin-1
0.61	GO:0032091	negative regulation of protein binding
0.60	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.57	GO:0000122	negative regulation of transcription by RNA polymerase II
0.55	GO:0001501	skeletal system development
0.55	GO:0060761	negative regulation of response to cytokine stimulus
0.54	GO:0040008	regulation of growth
0.51	GO:0031668	cellular response to extracellular stimulus
0.44	GO:0016055	Wnt signaling pathway

0.59	GO:0003714	transcription corepressor activity
0.38	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.41	GO:0005925	focal adhesion
0.40	GO:0043233	organelle lumen
0.38	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

sp|Q7T291|ADPRM_DANRE
Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
Search

ADPRM

0.96	Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase

0.36	GO:0034656	nucleobase-containing small molecule catabolic process
0.34	GO:0006468	protein phosphorylation

0.50	GO:0016787	hydrolase activity
0.36	GO:0046872	metal ion binding
0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003677	DNA binding

0.34	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.50

GO:0016787

sp|Q7T292|MFRN2_DANRE
Mitoferrin-2
Search

SLC25A28

0.92	Solute carrier family 25 (mitochondrial iron transporter), member 28

0.55	GO:0048250	mitochondrial iron ion transport
0.50	GO:0034755	iron ion transmembrane transport
0.46	GO:0055072	iron ion homeostasis
0.43	GO:0043249	erythrocyte maturation
0.42	GO:0035162	embryonic hemopoiesis
0.36	GO:0015684	ferrous iron transport

0.50	GO:0005381	iron ion transmembrane transporter activity
0.36	GO:0072509	divalent inorganic cation transmembrane transporter activity

0.46	GO:0005739	mitochondrion
0.42	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q7T293|SDE2_DANRE
Protein SDE2 homolog
Search

SDE2

0.94	Replication stress response regulator SDE2

0.57	GO:0051301	cell division
0.57	GO:0007049	cell cycle
0.56	GO:0006260	DNA replication
0.38	GO:0006508	proteolysis

0.48	GO:0003677	DNA binding
0.39	GO:0008233	peptidase activity

0.60

GO:0005634

nucleus

0.39

GO:0008233

tr|Q7T295|Q7T295_DANRE
Tyrosylprotein sulfotransferase 2
Search

TPST2

0.97	Tyrosylprotein sulfotransferase 2

0.84	GO:0006478	peptidyl-tyrosine sulfation
0.37	GO:0060468	prevention of polyspermy
0.36	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization
0.35	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process

0.84	GO:0008476	protein-tyrosine sulfotransferase activity
0.49	GO:0042803	protein homodimerization activity
0.32	GO:0003676	nucleic acid binding

0.48	GO:0012505	endomembrane system
0.43	GO:0043231	intracellular membrane-bounded organelle
0.42	GO:0044444	cytoplasmic part
0.40	GO:0098588	bounding membrane of organelle
0.40	GO:0031984	organelle subcompartment
0.38	GO:0031301	integral component of organelle membrane
0.36	GO:0070062	extracellular exosome

0.84

EC:2.8.2.20

GO:0008476

sp|Q7T297|F172A_DANRE
Protein FAM172A
Search

sp|Q7T2A3|DDA1_DANRE
DET1- and DDB1-associated protein 1
Search

DDA1

0.97	Placenta cross-immune reaction antigen 1 (Fragment)

0.84	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
0.34	GO:0043687	post-translational protein modification
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.37	GO:0016874	ligase activity
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0005515	protein binding

0.52	GO:0080008	Cul4-RING E3 ubiquitin ligase complex
0.33	GO:0005654	nucleoplasm
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.37